WorldWideScience

Sample records for ten years experience

  1. Choledochal cysts: our ten year experience.

    LENUS (Irish Health Repository)

    Cianci, F

    2012-04-01

    We present our experience in the management of choledochal cysts from 1999 to 2009. A retrospective review of all charts with a diagnosis of choledochal cysts in our institution in this ten-year period. Data was collated using Excel. A total of 17 patients were diagnosed with choledochal cyst: 9 females and 8 males. The average age at diagnosis was 28 months (range from 0 to 9 years). The most common presenting symptoms were obstructive jaundice 6 (35%) and abdominal pain and vomiting 4 (23%). Ultrasound (US) was the initial diagnostic test in all cases with 4 patients requiring further investigations. All patients underwent Roux-en-Y Hepaticojejunostomy. The average length of stay was 11 days. Patients were followed up with Liver Function Tests (LFTS) and US 4-6 weeks post-operatively. Three patients developed complications including post-op collection, high drain output requiring blood transfusion and adhesive bowel obstruction. Our overall experience with choledochal cyst patients has been a positive one with effective management and low complication rates.

  2. Ten years of the project Chain Experiment

    Science.gov (United States)

    Susman, Katarina; Ziherl, Saša; Bajc, Jurij

    2017-05-01

    In this paper the project Chain Experiment is presented. It can be viewed as a competition or as a popularization activity for science, technology, and physics in particular. We present the basic idea of a toppling-domino-like chain of contraptions that are operated one after another, and each demonstrates different physical phenomena. The evolution into its current form with three different types of activities is briefly described. The emphasis of the paper is on the impact of the project on physics education. The ways in which physics students, physics teachers, and participating pupils profit from the different project activities are presented in detail.

  3. Ten years of extensive green roof experience in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Grau, U.; Siemsen, M. [Humboldt Univ., Berlin (Germany). Inst. for Agrarian and Urban Ecological Projects; Gomez, G.N. [Chapingo Autonomous Univ., Chapingo (Mexico)

    2005-07-01

    This paper described the installation of an extensive green roof in Mexico City as part of a collaboration between a German and a Mexican university. While the plants used in the project were indigenous to Mexico, most of the materials and green roof technologies came from Germany. The aim of the project was to create an extensive green roof system on a low maintenance basis without additional irrigation, and to determine the limits of growth and development of the vegetation. The project was conducted on 4 identical adjacent flat roofs. After a layer of filter cloth was installed to avoid damage to the waterproof membrane, a drainage layer of expanded clay was installed with different thicknesses on each of the 4 roofs. The growing medium was composed of Mexican volcanic material, a mineral material from Germany, and organic material consisting of coco fibers and sugarcane residues. Eight different substrate mixtures were tested. After several years it became clear that it was possible to implement an extensive green roof under extreme climatic conditions. However, it was observed that some plant specimens only survived in certain areas of the roof. The roofs underwent a complete renovation, and surviving specimens were salvaged. Vulnerable areas where leakage occurred were detected near air conditioning units and perimeter areas. Overheating of the areas led to distortion and contraction of the membrane, which led to its failure. All perimeter areas were covered by a zinc sheet to avoid direct solar radiation on the unprotected membrane. The selected plant material required supplemental irrigation during the first 2 months. No further additional watering was given. Ten months later, the vegetation was well established and had covered the surface density. One of the roofs was instrumented to measure a series of factors such as precipitation, stormwater runoff, temperature underneath a roof membrane. It was concluded that some plant species are capable of surviving

  4. [Acute pyelonephritis treated under "home hospitalization." Ten years' experience].

    Science.gov (United States)

    Regalado, José; Mendoza, Humberto; Aizpuru, Felipe; Altuna, Elena; Gómez, Montserrat; Cía, Juan M

    2006-12-01

    We present the experience of the Vitoria-Gasteiz Hospital at Home Unit in the treatment of acute pyelonephritis, including an analysis of potential predictors of failure. A total of 369 episodes of acute pyelonephritis without septic shock or renoureteral obstruction are described. After initiating intravenous antibiotic therapy in the hospital emergency department, all patients were referred to the HH. We analyzed the characteristics of the cases and the relationship between several clinical factors and failure of HH care, defined as the need to readmit the patient to conventional hospitalization. During the study period, 280 women and 89 men (age 16-88 years) met the inclusion criteria. Mean length of HH stay was 5 days and duration of intravenous therapy was 3 days. Sixteen of the 369 cases (4%) had to be readmitted to the hospital because of hypotension, vomiting, pain, fever, or signs of obstruction on ultrasound or because they requested it (four patients). Patients who were readmitted had a higher maximum temperature (mean 39.4 vs. 38.7 degrees C; p = 0.006) than those who remained at the HH. There were no differences between the groups with respect to the other clinical variables studied. The evolution of all 16 hospitalized patients was favorable; only one required a urological intervention. Hospital at home care was an effective alternative for managing acute pyelonephritis without shock in 96% of cases referred by the emergency department, and obviated conventional hospital admission, which is usually indicated for this disease.

  5. Ten-year experience of insulin treatment in gestational diabetes.

    Science.gov (United States)

    Berne, C; Wibell, L; Lindmark, G

    1985-01-01

    Between 1975-1984, 119 women with gestational diabetes (GDM) were treated with insulin in Uppsala, representing a mean yearly incidence of 4.5/1,000 pregnancies. Women with GDM were older and more obese than the general pregnant population. Insulin treatment was instituted during a 5-7 day stay in hospital. The mean total daily dose of insulin prepartum, when fasting blood glucose had been normalized, was 53 (SD +/- 25) units (34 +/- 15 units of rapid-acting and 20 +/- 11 units of medium-acting insulin), divided into two doses daily. Mean duration of treatment was 6.4 weeks. The perinatal mortality was 0.8%, compared with 7.4% in previous pregnancies in the same women. The perinatal morbidity was generally mild and included hypoglycaemia (10.9%), hyperbilirubinaemia requiring treatment (2.5%), shoulder dystocia (2.5%) and one case of mild respiratory distress syndrome. The rate of macrosomia was reduced in the present pregnancies compared with previous ones in the women with GDM, but not abolished completely, probably because of too short a duration of improved metabolic control. Spontaneous delivery was favoured and the rate of Caesarean section was 13.5%. Thus, treatment with high doses of insulin in an unselected group of women with GDM is feasible. Normal perinatal mortality, reduced macrosomia, and no gross perinatal morbidity was found in the infants. Though the extent to which insulin treatment per se contributed to the favourable outcome is difficult to assess, it is suggested that the case for a high level of ambition for metabolic normalization in GDM should be a subject of further study.

  6. Radiosurgery as treatment for acoustic neuroma. Ten years' experience.

    Science.gov (United States)

    Llópez Carratalá, Ignacio; Escorihuela García, Vicente; Orts Alborch, Miguel; de Paula Vernetta, Carlos; Marco Algarra, Jaime

    2014-01-01

    The acoustic neuroma is a benign tumour that usually affects the vestibular portion of the vestibulocochlear nerve. It represents 8% of all intracranial tumours and 80% of those arising at the cerebellopontine angle. There are 3 treatment options: microsurgery (the technique of choice), radiosurgery and observation. The objective of the study was to evaluate the results and side effects obtained using radiosurgery as treatment for acoustic neuroma. We performed a review of all patients treated with radiosurgery (Gamma Knife and linear accelerator) at doses of 1200-1300 cGy for unilateral acoustic neuroma in our hospital from January 1999 until January 2010. In all patients we evaluated the overall state, tumour growth control rate (tumour smaller or remaining the same size), the involvement of v and vii cranial nerves and central nervous system disorders. We also assessed follow-up time and changes in hearing thresholds after radiosurgery. From a total of 35 patients studied, with a mean age of 58.29 years and lacking statistically significant differences in gender, the tumour growth control rate was over 90%. The main reason for visit (65.71%) was unilateral and progressive hearing loss. After treatment, 34.28% of patients had hearing loss. The involvement of the cranial nerves (v-vii) was transitory in 100% of cases. Gamma Knife radiosurgery was administered in 82.85% of patients. Although microsurgery is the treatment of choice for acoustic neuroma, we consider radiosurgery as a valid alternative in selected patients (elderly, comorbidity, small tumour size and sensorineural hearing loss, among others). Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial. All rights reserved.

  7. Affordances: Ten Years On

    Science.gov (United States)

    Brown, Jill P.; Stillman, Gloria

    2014-01-01

    Ten years ago the construct, affordance, was rising in prominence in scholarly literature. A proliferation of different uses and meanings was evident. Beginning with its origin in the work of Gibson, we traced its development and use in various scholarly fields. This paper revisits our original question with respect to its utility in mathematics…

  8. Ten year experience with antiretroviral treatment in Cambodia: Trends in patient characteristics and treatment outcomes.

    Directory of Open Access Journals (Sweden)

    Phirum Lay

    particularly high in the first few program years. A lower risk was observed among individuals starting ART during the 2006-2008 period. Factors independently associated with an increased risk of treatment failure included ART-experience, NVP-based ART and a baseline CD4 count below 200 cells/μL.Overall program outcomes were fair, and generally compare well to other reports from the region. Despite gradually earlier initiation of ART over the ten year period, ART is still initiated at too low CD4 count levels, warranting increased efforts for early HIV diagnosis and enrolment/retention into HIV care. Tailored strategies for poor prognostic groups (older age, male, low BMI should be designed and evaluated.

  9. Ten year experience with antiretroviral treatment in Cambodia: Trends in patient characteristics and treatment outcomes.

    Science.gov (United States)

    Lay, Phirum; An, Sokkab; Soeung, Sunpiseth; Srey, Pich Sovannary; Thai, Sopheak; Lynen, Lutgarde; Griensven, Johan van

    2017-01-01

    particularly high in the first few program years. A lower risk was observed among individuals starting ART during the 2006-2008 period. Factors independently associated with an increased risk of treatment failure included ART-experience, NVP-based ART and a baseline CD4 count below 200 cells/μL. Overall program outcomes were fair, and generally compare well to other reports from the region. Despite gradually earlier initiation of ART over the ten year period, ART is still initiated at too low CD4 count levels, warranting increased efforts for early HIV diagnosis and enrolment/retention into HIV care. Tailored strategies for poor prognostic groups (older age, male, low BMI) should be designed and evaluated.

  10. Oral mucosal lesions in children from 0 to 12 years old: ten years' experience.

    Science.gov (United States)

    Majorana, Alessandra; Bardellini, Elena; Flocchini, Pierangela; Amadori, Francesca; Conti, Giulio; Campus, Guglielmo

    2010-07-01

    The exact prevalence of oral lesions in childhood is not well known. We sought to define the prevalence of oral mucosal lesions in a large group of children. A retrospective cross-sectional study was performed using clinical charts from January 1997 to December 2007. Data collected included age, gender, and pathologic diagnosis. In total, 10,128 children (0-12 years old) were enrolled. Clinical diagnostic criteria proposed by the World Health Organization were followed. The frequency of children presenting oral mucosal lesions was 28.9%, and no differences related to gender were observed. The most frequent lesions recorded were oral candidiasis (28.4%), geographic tongue and other tongue lesions (18.5%), traumatic lesions (17.8%), recurrent aphthous ulcerations (14.8%), herpes simplex virus type 1 infections (9.3%), and erythema multiforme (0.9%). Children suffering from chronic diseases had a higher frequency of oral lesions compared with healthy children (chi-square: P oral disorders are associated with underlying medical conditions. Copyright (c) 2010 Mosby, Inc. All rights reserved.

  11. Global public-private health partnerships: lessons learned from ten years of experience and evaluation.

    Science.gov (United States)

    Buse, Kent; Tanaka, Sonja

    2011-08-01

    Global Health Partnerships (GHPs) have contributed significantly to improved global health outcomes as well as the manner in which global health is governed. Yet in a context of an increasingly complex global health landscape, resource scarcity and a shift from disease-specific to systems strengthening approaches, it is important to continually enhance and apply our understanding of how to improve GHP performance. The authors reviewed and synthesised findings from eight independent evaluations of GHPs as well as research projects conducted by the authors over the past several years, the most recent of which involved semi-structured discussions with 20 'partnership pioneers'. This paper presents the major drivers of the GHP trend, briefly reviews the significant contributions of GHPs to global health and sets out common findings from evaluations of these global health governance instruments. The paper answers the question of how to improve GHP performance with reference to a series of lessons emerging from the past ten years of experience. These lessons cover the following areas: • Value-added and niche orientation • Adequate resourcing of secretariats • Management practices • Governance practices • Ensuring divergent interests are met • Systems strengthening • Continuous self-improvement. These and other critical reflections inform the 'what's next' agenda for GHP development. © 2011 FDI World Dental Federation.

  12. Ten Years of Chandra

    Science.gov (United States)

    Weisskopf, Martin C.

    2009-01-01

    We celebrated the 10-th anniversary of the Launch of the Chandra X-ray Observatory on July 13, 2009. During these 10 years data from this Great Observatory have had a profound impact on 21st century astrophysics. With its unrivaled capability to produce sub-arcsecond images, the Observatory has enabled astronomers to make new discoveries in topics as diverse as comets and cosmology. We shall review some of the highlights, discuss the current status, and future plans.

  13. Implantable cardioverter defibrillator therapy: ten years experience in a medical center.

    Science.gov (United States)

    Chen, Tien-En; Wang, Chun-Chieh; Chang, Shang-Hung; Yeh, San-Jou; Wu, Delon

    2008-01-01

    An implantable cardioverter defibrillator (ICD) is the therapy of choice for survivors of life-threatening ventricular tachyarrhythmias or sudden cardiac death. To date there is little data concerning the clinical features and outcome of ICD therapy among Taiwanese. This study identifies factors related to the outcome of ICD therapy over a ten-year period at this institution. Forty-nine ICDs were implanted in 46 patients between August 1996 and January 2006. The mean follow-up duration was 32 +/- 21 months. Patient data, primary cardiac diagnosis, presenting cardiac arrhythmia, echocardiographic parameters, hemodynamic indexes, electrophysiologic findings, and follow-up observations were analyzed. The findings were compared to those of the Taiwan ICD Multicenter Registry (TIMR) Study and major secondary prevention ICD trials in the literature. The patients in this study were comparable to those of TIMR but were younger and had better left ventricular ejection fractions (LVEF) than those in Western countries. Furthermore, higher mortality on follow-up was observed in patients with any of the following: LVEF or = 55 mm, a left ventricular end diastolic dimension > or = 75 mm, an end systolic dimension > or = 60 mm, triple vessel disease, a prior anterior myocardial infarction, and amiodarone or diuretic therapy. Patients with structural heart disease other than ischemic heart disease or dilated cardiomyopathy had higher event recurrence rates. Left ventricular function is a major determinant affecting the outcome in ICD recipients. Aggressive treatment for heart failure is warranted in these patients.

  14. [Home parenteral nutrition in patients with advanced cancer: experience of a single centre over ten years].

    Science.gov (United States)

    Moreno Villares, J M; Gomis Muñoz, P; Valero Zanuy, Ma A; León Sanz, M

    2004-01-01

    The use of Home Parenteral Nutrition (HPN) in patients with advanced cancer without the possibility of curative treatment continues to be a controversial subject entailing a considerable emotional burden. Nonetheless, this group of patients constitutes the main indication for HPN in many programmes. To present the characteristics of a series of patients included on an HPN programme over the last ten years. Retrospective study of the case histories of the 11 patients who received HPN over this period. The demographic and clinical details were noted along with their complications and evolution for comparison with those of a control group of patients with benign disease receiving HPN over the same period. For the comparisons, Student's t test and the chi-squared test were used as and when indicated. Results were considered statistically significant if p < 0.05. Eleven patients received HPN, nine of them because of an irresoluble intestinal obstruction and two because of a high flow fistula. The mean age at the start of HPN was 50.8 +/- 12.7 years versus 37.3 +/- 17.2 years for the group with benign disease (p < 0.05). The mean duration of HPN was 71.05 +/- 217 days in the first group, notably less than the second (387.15 +/- 995.85; p < 0.05), with a range between 5 and 760 days. The patients received the infusion through a previously implanted subcutaneous reservoir (n = 9) and on two occasions, electively, through a tunnelled catheter. The infection rate was higher in the group with cancer (0.34 episodes per patient and 1,000 days on HPN) than in the group with benign disease (0.08 episodes; p < 0.05). HPN was suspended in only one of the patients more than 5 days prior to death due to clinical deterioration. Two patients required admission due to a complication associated with the technique. In both cases, a fungal infection of the blood made it necessary to withdraw the catheter. The quality of life, measured by means of an activity scale, was similar at the start

  15. Ten years of clinical experience with biosimilar human growth hormone: a review of safety data.

    Science.gov (United States)

    Borrás Pérez, Maria Victoria; Kriström, Berit; Romer, Tomasz; Walczak, Mieczyslaw; Höbel, Nadja; Zabransky, Markus

    2017-01-01

    Safety concerns for recombinant human growth hormone (rhGH) treatments include impact on cancer risk, impact on glucose homeostasis, and the formation of antibodies to endogenous/exogenous GH. Omnitrope(®) (biosimilar rhGH) was approved by the European Medicines Agency in 2006, with approval granted on the basis of comparable quality, safety, and efficacy to the reference medicine (Genotropin(®)). Additional concerns that may exist in relation to biosimilar rhGH include safety in indications granted on the basis of extrapolation and the impact of changing to biosimilar rhGH from other rhGH treatments. A substantial data set is available to fully understand the safety profile of biosimilar rhGH, which includes data from its clinical development studies and 10 years of post-approval experience. As of June 2016, 106,941,419 patient days (292,790 patient-years) experience has been gathered for biosimilar rhGH. Based on the available data, there have been no unexpected or unique adverse events related to biosimilar rhGH treatment. There is no increased risk of cancer, adverse glucose homeostasis, or immunogenic response with biosimilar rhGH compared with the reference medicine and other rhGH products. The immunogenicity of biosimilar rhGH is also similar to that of the reference and other rhGH products. Physicians should be reassured that rhGH products have a good safety record when used for approved indications and at recommended doses, and that the safety profile of biosimilar rhGH is in keeping with that of other rhGH products.

  16. Ten years' clinical experience with biosimilar human growth hormone: a review of efficacy data.

    Science.gov (United States)

    López-Siguero, Juan Pedro; Pfäffle, Roland; Chanson, Philippe; Szalecki, Mieczyslaw; Höbel, Nadja; Zabransky, Markus

    2017-01-01

    In 2006, the European Medicines Agency (EMA) approved Omnitrope(®) as a biosimilar recombinant human growth hormone (rhGH), on the basis of comparable quality, safety, and efficacy to the reference medicine (Genotropin(®), Pfizer). Data continue to be collected on the long-term efficacy of biosimilar rhGH from several on-going postapproval studies. Particular topics of interest include efficacy in indications granted on the basis of extrapolation, and whether efficacy of growth hormone treatment is affected when patients are changed to biosimilar rhGH from other rhGH products. Data from clinical development studies and 10 years of postapproval experience affirm the clinical efficacy and effectiveness of biosimilar rhGH across all approved indications. In addition, the decade of experience with biosimilar rhGH since it was approved in Europe confirms the scientific validity of the biosimilar pathway and the approval process. Concerns about clinical effect in extrapolated indications, and also about the impact of changing from other rhGH preparations, have been alleviated. Biosimilar rhGH is an effective treatment option for children who require therapy with rhGH.

  17. Ten year experience of bioabsorbable mesh support in pectus excavatum repair.

    Science.gov (United States)

    Luzzi, L; Voltolini, L; Zacharias, J; Campione, A; Ghiribelli, C; Di Bisceglie, M; Gotti, G

    2004-12-01

    We reviewed 10 years experience in the treatment of this deformity using a retro-sternal bioabsorbable mesh in place of a metallic device to lift and stabilise the sternum. Moreover, the mesh supports the thoracic and upper abdominal wall reconstruction. From January 1990 to December 2000, in our Thoracic Surgery Unit, 65 patients with PE were assessed for surgical repair, mean age 16+/- 3.5 years, fronto sagittal thoracic index (FSTI) 0.21, ranging from 0.15-0.33. Twenty-three of them underwent surgical correction after initial assessment, 22 were deferred and sent to physiotherapy. At a subsequent assessment, five of the patients sent to physiotherapy were deemed to require surgery. Of the 28 patients who underwent surgery, 2 (10%) presented a mild recurrence of PE after 1 year (0.300.34), meanwhile all other patients maintained a FSTI>0.34. For all patients the improvement in FSTI was statistically significant, p = 0.001. Patients satisfaction after 24 months was thus shared: excellent 18 patients (65%), good seven patients (25%), fair one patient (3.5%) and poor two patients (7%). No major complications were observed in preoperative period. Patients mobilisation was soon achieved thanks to the postoperative pain control and the absence of retro-sternal metallic support. The introduction of bioabsorbable mesh in the Robicsek technique is a safe procedure related to a high percentage of success. The high tolerance of the material reduces the inflammatory reaction. Moreover, the procedure prevents patients from having complications caused by retro-sternal device dislodgment, avoiding a second intervention for device reposition and reducing the postoperative chest pain achieving an early patient mobilisation. In the end a complete reconstruction of the upper abdomen wall has been produced.

  18. Cord Blood Banking and Transplantation in China: A Ten Years Experience of a Single Public Bank.

    Science.gov (United States)

    Liu, Jinhui; He, Ji; Chen, Shu; Qin, Fei; Wang, Fang; Xu, Gang; Zhu, Faming; Lv, Hangjun; Yan, Lixing

    2012-02-01

    BACKGROUND: Umbilical cord blood (UCB) has successfully used for transplantation to treat hematologic malignancies and genetic diseases. Herein, we describe the experience generated in a single public UCB bank at Zhejiang Province in China. METHODS: Good manufacturing practice and standard operating procedures were used to address donor selection as well as UCB collection, processing, and cryopreservation. Total nucleated cells (TNCs), cellular viability, CD34+ cells, and colony-forming units were determined, and infectious diseases screening test, sterility test, and HLA typing for UCB units were done. RESULTS: Only 18.51% of all collected UCB units met storage criteria, and 7,056 UCB units were cryopreserved in 10 years. The volume of UCB units was 95.0 ± 22.0 ml. The number of TNCs before and after processing was 13.32 ± 3.63 × 10(8) and 10.63 ± 2.80 × 10(8), respectively, and the recovery rate was 80.71 ± 11.26%. 0.4344 ± 0.1874% of the TNCs were CD34+ cells. The CFU-GM was 32.1 ± 28.0 colonies per 1 × 10(5) nucleated cells. Based mainly on HLA and nucleated cell content, 26 UCB units were released for transplantation. CONCLUSIONS: A public UCB bank was successfully established in China; collection and processing of UCB units should be optimized in order to gain maximum volume and cell count.

  19. Ten years' clinical experience with biosimilar human growth hormone: a review of efficacy data

    Directory of Open Access Journals (Sweden)

    López-Siguero JP

    2017-05-01

    Full Text Available Juan Pedro López-Siguero,1 Roland Pfäffle,2 Philippe Chanson,3 Mieczyslaw Szalecki,4,5 Nadja Höbel,6 Markus Zabransky6 1Servicio de Endocrinología Pediátrica, Hospital Materno-Infantil, Hospital Regional Universitario de Málaga, Spain; 2University Children’s Hospital Leipzig, Germany; 3Department of Endocrinology and Reproductive Diseases, Hôpital de Bicêtre, Hôpitaux Universitaires Paris-Sud, Assistance Publique-Hôpitaux de Paris and University Paris-Sud, Le Kremlin-Bicêtre, France; 4Clinic of Endocrinology and Diabetology, Children’s Memorial Health Institute, Warsaw, Poland; 5Faculty of Medicine and Health Sciences UJK, Kielce, Poland; 6Sandoz Biopharmaceuticals, Hexal AG, Holzkirchen, Germany Abstract: In 2006, the European Medicines Agency (EMA approved Omnitrope® as a biosimilar recombinant human growth hormone (rhGH, on the basis of comparable quality, safety, and efficacy to the reference medicine (Genotropin®, Pfizer. Data continue to be collected on the long-term efficacy of biosimilar rhGH from several on-going postapproval studies. Particular topics of interest include efficacy in indications granted on the basis of extrapolation, and whether efficacy of growth hormone treatment is affected when patients are changed to biosimilar rhGH from other rhGH products. Data from clinical development studies and 10 years of postapproval experience affirm the clinical efficacy and effectiveness of biosimilar rhGH across all approved indications. In addition, the decade of experience with biosimilar rhGH since it was approved in Europe confirms the scientific validity of the biosimilar pathway and the approval process. Concerns about clinical effect in extrapolated indications, and also about the impact of changing from other rhGH preparations, have been alleviated. Biosimilar rhGH is an effective treatment option for children who require therapy with rhGH. Keywords: recombinant human growth hormone, Omnitrope®, biosimilar

  20. Ten years of experience in combining ecology and navigation on Dutch waterways

    NARCIS (Netherlands)

    Boeters, R.E.A.M.; Havinga, H.; Litjens, G.; Verheij, H.J.

    1997-01-01

    In this paper we will discuss the experience gained in the Netherlands with the multifunctional management of waterways. We will especially go into how the functions of rivers and canals for navigation and nature are combined. For this we will briefly go back to the national paper for Seville 1994,

  1. The Fundacion Universidad Empresa of Madrid, Ten Years of Experience in University-Industry Relations.

    Science.gov (United States)

    Saenz de Miera, Antonio

    1983-01-01

    The first 10 years of Spain's leading organization designed to promote the establishment of relationships between universities and industry are discussed. Its activities in scientific and technical research projects and funding, continuing education programs, and coordination of employment opportunities are outlined. (MSE)

  2. A ten-year experience of physical Intimate partner violence (IPV) in a French forensic unit.

    Science.gov (United States)

    Savall, Frédéric; Lechevalier, Agathe; Hérin, Fabrice; Vergnault, Marion; Telmon, Norbert; Bartoli, Christophe

    2017-02-01

    Forensic units have a central role to play in healthy public policy, by the collection and management of violence. This study aims to describe the characteristics of physical Intimate Partner Violence (IPV) against men reported over 10 years in the forensic unit of Toulouse (France) and to compare them with the characteristics of physical IPV against women over the same period. All the medico-legal reports of male victims over 18 years of age between 2005 and 2014 were analyzed. Female victims over 18 years of age in the same period were randomized by year in order to study a similar number of individuals. We analyzed 712 forensic reports of male victims and 865 forensic reports of female victims. Repeated consultation concerned 20.5% of women and 7.5% of men (p IPV against women was more frequent than against men, while physical IPV against men seemed to be more severe than against women. The distribution of alleged manners of attack and injuries were consistent with previous studies. However, the mechanisms of the origin of the process of violence are difficult to apprehend in such a dyadic context. The findings should be interpreted with caution, but they provide original and substantial material, which can be useful in recognizing victims and in developing preventive strategies. With this aim, forensic units have a central role to play in the collection of violence and in individualized management. In France, this subject has not been extensively studied and future research is needed to emphasize the characteristics of IPV in order to better understand the phenomenon and to create and assess public policies in order to prevent it. Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  3. Ten-year experience with the Swenson procedure in Nigerian children with Hirschsprung′s disease

    Directory of Open Access Journals (Sweden)

    Sowande Oludayo

    2011-01-01

    Full Text Available Background: Hirschsprung′s disease (HD is a common cause of intestinal obstruction in children. Definitive treatments consist of excision of the aganglionic segment and anastomosing the normal colon to the anal remnant. The outcome of this approach in Nigerian children is not known. The aim of this study was to analyze the short to mid-term outcome of children who have undergone the Swenson Procedure (SPT as a treatment of HD over a period of 10 years. Patients and Methods: The clinical data of biopsy-proven cases of HD managed at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria, between 1998 and 2007 were reviewed. Results: There were 33 children 28 were males and five were females (M 5.6: F = 1. The median age at presentation was eight months (range three days to 11 years. Eighteen (54.5% patients had primary pull-through without colostomy while 15 (45.5% patients had a two-staged operation. The operation was carried out at a median age of 14 months with a range of seven weeks to 11 years, four months. Twenty-one (64% of the patients were older than one year at the time of surgery. The level of aganglionosis was in the recto-sigmoid area in 30 (91% patients. The commonest post-SPT complication was intestinal obstruction from adhesions. Bowel opening varied from once daily to eight times daily, median thrice daily. Conclusion: The Swenson′s Procedure is an effective procedure in the treatment of HD in children in Ile Ife, Nigeria.

  4. Tracheostomy in children: a ten-year experience from a tertiary center in southern Brazil.

    Science.gov (United States)

    Schweiger, Cláudia; Manica, Denise; Becker, Carolina Fischer; Abreu, Larissa Santos Perez; Manzini, Michelle; Sekine, Leo; Kuhl, Gabriel

    2016-08-24

    Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications. To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities, complications and decannulation rates. Retrospective study concerning patients under 18 years of age undergoing tracheostomy in a tertiary health care center, from January 2006 to November 2015. One hundred and twenty-three children required a tracheostomy after ENT evaluation during the study period. A proportion of 63% was male, and 56% was under one year of age. Glossoptosis was the most common indication (30%), followed by subglottic stenosis (16%) and pharyngomalacia (11%). The mortality rate was 31%. By the end of this review, 35 children (28.4%) had been decannulated, and the fewer the number of comorbidities, the greater the decannulation rate (0.77±0.84 vs. 1.7±1.00 comorbidities; p<0.001). Tracheostomy in children is a relatively frequent procedure at our hospital. The most common indications are glossoptosis and subglottic stenosis. A high mortality rate was found, potentially substantiated by the high number of critical care patients with chronic neurological conditions in this cohort. Our decannulation rate is slightly below other series, probably because of the greater amount of patients with comorbidities. Copyright © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  5. Ten years' experience with an external quality control program for semen analysis.

    Science.gov (United States)

    Mallidis, Con; Cooper, Trevor G; Hellenkemper, Barbara; Lablans, Martin; Uckert, Frank; Nieschlag, Eberhard

    2012-09-01

    To gauge the performance of laboratories and impact of the German semen analysis external quality control program (QuaDeGA) over its first 10 years. Retrospective analysis of QuaDeGA's twice yearly distribution of fixed semen samples and electronic material documenting sperm motility. Ranking of each participant's responses was determined according to their relation to a "target window." Multicenter. PAITENT(S): Healthy donors. None. Laboratory performance, World Health Organization (WHO) adherence. Over 19 runs, there was a steady increase of participants (280 laboratories), the largest group being private urologic practices. Although use of WHO-recommended Neubauer chamber (from 33% to 55%) and diluent (from 11% to 32%) increased, the opposite occurred with morphology staining protocols (from 41% to 19%). Overall, <8% of laboratories truly followed WHO guidelines. Median-based comparisons, replacing reference laboratories, resulted in a merging of performance rankings regardless of the protocols used. Adherence to WHO recommendations is low, with the majority of laboratories using methods expressly opposed by the guidelines. Participation in QuaDeGA was found to improve the performance of the laboratories involved in the program. However, the use of median-based ranking, while decreasing the extent of variance between laboratories, brings into question the significance of the rankings. Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  6. A Ten-Year Reflection

    Science.gov (United States)

    Phillip, Cyndi

    2016-01-01

    Five initiatives launched during Cyndi Phillip's term as American Association of School Librarians (AASL) President (2006-2007) continue to have an impact on school librarians ten years later. They include the rewriting of AASL's learning standards, introduction of the SKILLS Act, the presentation of the Crystal Apple Award to Scholastic Library…

  7. Barrett's esophagus: Ten years of experience at a tertiary care hospital center in Mexico.

    Science.gov (United States)

    Valdovinos-Andraca, F; Bernal-Méndez, A R; Barreto-Zúñiga, R; Briseño-García, D; Martínez-Lozano, J A; Romano-Munive, A F; Elizondo-Rivera, J; Téllez-Ávila, F I

    2017-05-24

    The prevalence of Barrett's esophagus has been calculated at between 1.3 and 1.6%. There is little information with respect to this in Mexico. To determine the frequency and characteristics of Barrett's esophagus in patients that underwent endoscopy at a national referral center, within a 10-year time frame. The databases of the pathology and gastrointestinal endoscopy departments of the Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" were analyzed, covering the period of January 2002 to December 2012. Patients with a histologic diagnosis of Barrett's esophagus were included. The variables of age, sex, the presence of dysplasia/esophageal adenocarcinoma, Barrett's esophagus length, and follow-up were analyzed. Of 43,639 upper gastrointestinal endoscopies performed, 420 revealed Barrett's esophagus, corresponding to a frequency of 9.6 patients for every 1,000 endoscopies. Of those patients, 66.9% (n=281) were men, mean patient age±SD was 57.2±15.3 years, 223 patients (53%) presented with long-segment Barrett's esophagus, and 197 (47%) with short-segment Barrett's esophagus. Dysplasia was not present in 339 patients (80.7%). Eighty-one (19.3%) patients had some grade of dysplasia or cancer: 48/420 (11.42%) presented with low-grade dysplasia, 20/420 (4.76%) with high-grade dysplasia, and 13/420 (3.1%) were diagnosed with esophageal cancer arising from Barrett's esophagus. Mean follow-up time was 5.6 years. The frequency of Barrett's esophagus was 9.6 cases for every 1,000 upper gastrointestinal endoscopies performed. Dysplasia was not documented in the majority of the patients with Barrett's esophagus and they had no histopathologic changes during follow-up. A total of 19.3% of the patients presented with dysplasia or cancer. Copyright © 2017 Asociación Mexicana de Gastroenterología. Publicado por Masson Doyma México S.A. All rights reserved.

  8. Ten years of measurements from the Atmospheric Chemistry Experiment Satellite Mission

    Science.gov (United States)

    Walker, Kaley; McElroy, C. Thomas; Bernath, Peter F.; Boone, Chris

    Recently, the Canadian-led Atmospheric Chemistry Experiment (ACE) satellite mission has completed a decade of measurements from orbit. This Canadian-led scientific satellite uses infrared and UV-visible spectroscopy to investigate the chemistry and dynamics of the Earth's atmosphere. The primary instrument on-board, the ACE Fourier Transform Spectrometer (ACE-FTS) is a high-resolution (0.02 cm (-1) ) FTS operating between 750 and 4400 cm (-1) . It also contains two filtered imagers (0.525 and 1.02 microns) to measure atmospheric extinction due to clouds and aerosols. The second instrument is a dual UV-visible-NIR spectrophotometer called ACE-MAESTRO (Measurements of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation) which extends the ACE wavelength coverage to the 280-1030 nm spectral region. The ACE instruments make solar occultation measurements from which altitude profiles of atmospheric trace gas species, temperature and pressure are retrieved. The 650 km altitude, 74 degree circular orbit provides global measurement coverage with a focus on the Arctic and Antarctic regions. These results are being used for studies relating to ozone depletion, climate-chemistry coupling and air pollution. As well, the decade long time series has been used to investigate trends in atmospheric constituents. This presentation will give an overview of the mission status and will provide a survey of the scientific results obtained from ACE.

  9. The Ross Procedure in Patients among the Pediatric Population, Post Ten Years of Experience

    Directory of Open Access Journals (Sweden)

    Andrey A. Ivanov

    2013-09-01

    Full Text Available The aim of the study was to analyze the results of the surgical treatment in pediatric patients who had undergone the Ross procedure.Material and Methods: The study involved 114 patients between 12 days to 18 years in age. The early and late (up to 5 years results of the treatment were studied. The examination included echocardiography, catheterization of the cardiac chambers and angiocardiography. The case distribution of patients based on diagnosis was as follows: isolated aortic valve stenosis (IAVS in 38 (33.3% patients, aortic valve insufficiency (AVI in 33 (28.9%, and combined heart defects in 56 patients (49.1%.Results: The death rate was 6.14% during the early postoperative period and 1.14% in the late postoperative period; the actuarial survival in the long-term was 98.86%. The complication rate was 51.5%. The most frequent complication was pericarditis (25.6%, whereas cardiac and respiratory failure occurred in 7.6% of the cases and cardiac arrhythmias in 6.1% of the cases. The average time spent in the intensive care unit was 3.48 ± 2.90 days; the hospitalization period on average was 24.70±10.87 days. After surgery, there was a tendency of the echocardiographic parameters to move toward normalization. The frequency of reoperation in the late period was 23.7%, the main reason for which being the conduit dysfunction in the position of the pulmonary artery (PA.Conclusion: The clinical efficacy of the Ross procedure in the treatment of aortic valve malformations in the pediatric group was confirmed. However, in some cases, the need to perform repeated operations due to the increase in the ring size and an increase in the neo-aortic insufficiency during the somatic growth process.

  10. Ten-year single-centre experience with type II endoleaks: Intervention versus observation.

    Science.gov (United States)

    Haq, Ikram-Ul; Kelay, Arun; Davis, Meryl; Brookes, Jocelyn; Mastracci, Tara M; Constantinou, Jason

    2017-08-01

    Our objective was to determine the relative merits of intervention or observation of type II endoleaks (T2Ls). A retrospective analysis was performed on 386 infra-renal endovascular aneurysm repair (IR-EVAR) patients from 2006 to 2015. Annual surveillance imaging of patients undergoing EVAR at our centre were analysed, and all endoleaks were subjected to a multidisciplinary team meeting for consideration and treatment. In the 10-year time frame, 386 patients (79.5±8.7 years) underwent an IR-EVAR. Eighty-one patients (21.0%) developed a T2L and intervention was undertaken in 28 (34.6%): 17 (60.7%) were treated via a transarterial approach (TA) and 11 (39.3%) using the translumbar approach (TL). Fifty-three patients (65.4%) with T2Ls were managed conservatively. Patients who received T2L treatment had a greater proportion of recurrent T2Ls than patients who were conservatively managed ( p=0.032). T2Ls associated with aneurysmal growth were more resistant to treatment than those where there was no change or a decrease in aneurysm size during follow-up (0.033). There was no significant difference in the TA and TL approach with respect to endoleak repair success ( p=0.525). Treatment of a T2L did not confer a survival advantage compared to conservative management ( p=0.449) nor did the choice of either the TA or TL approach ( p=0.148). Our study suggests the development of a T2L associated with aneurysm growth may represent an aggressive phenotype that is resistant to treatment. However, this did not lead to an increased risk of mortality over follow-up. Neither a transarterial nor a translumbar approach to treating a T2L conferred superiority.

  11. Extranodal marginal zone non Hodgkin's lymphoma of the lung: A ten-year experience

    Directory of Open Access Journals (Sweden)

    Milošević Violeta

    2011-01-01

    Full Text Available Background/Aim. Bronchus-associated lymphoid tissue (BALT lymphoma is a rare subtype of low grade marginal zone B cell lymphoma representing 10% of all MALT lymphomas. The purpose of this study was to analyze the outcome of this group of patients comparing prognostic parameters and therapy modalities. Methods. A total of eight patients with BALT lymphoma had diagnosed between January 1998 - April 2008 at the Institute of Hematology, Clinical Center of Serbia, Belgrade, and they were included in this retrospective analysis. Results. Male/female ratio was 2/6, the median age was 64 years (range 37-67 years. Six patients had nonspecific respiratory symptoms and all of them had B symptoms. The patients were seronegative for HIV, HCV and HBsAg. Three patients had Sjogren's syndrome, rheumatoid arthritis and pulmonary tuberculosis, respectively. Seven patients were diagnosed by transbronchial biopsy and an open lung biopsy was done in one patient. Patohistological findings revealed lymphoma of marginal zone B cell lymphoma: CD20+/CD10-/CD5-/CyclinD1- /CD23-/IgM- with Ki-67+<20% of all cells. According to the Ferraro staging system, five patients had localized disease (CS I-IIE and three had stage IVE; bulky tumor mass had 3 patients. All patients had Eastern Cooperative Oncology Group (ECOG performance status (PS 0 or 1. Five patients received monochemotherapy with chlorambucil and 3 were treated with CHOP regimen (cyclophosphamide, doxorubicin, vincristine and prednisone. A complete response (CR was achieved in 5 patients and a partial response (PR in 3 of them, treated with chlorambucil monotherapy and CHOP regimen. All patients were alive during a median follow-up period of 49 months (range 6- 110 months. Three patients relapsed after monochemotherapy into the other extranodal localization. They were treated with CHOP regimen and remained in stable PR. Conclusion. BALT lymphoma tends to be localised disease at the time of diagnosis, responds well

  12. Ten-year experiences of the tuberculosis control programme in the southern region of Ethiopia.

    Science.gov (United States)

    Yassin, M A; Datiko, D G; Shargie, E B

    2006-10-01

    The tuberculosis control programme, southern region of Ethiopia. To assess the impact of the expansion of the DOTS strategy on tuberculosis (TB) case finding and treatment outcome. Reports of TB patients treated since the introduction of DOTS in the region were reviewed. Patients were diagnosed and treated according to World Health Organization (WHO) recommendations. Case notification and treatment outcome reports were compiled quarterly at district level and submitted to the regional programme. Of 136,572 cases registered between 1995 and 2004, 47% were smear-positive, 25% were smear-negative and 28% had extra-pulmonary tuberculosis (EPTB). In 2004, 94% of the health institutions were covered by DOTS. Between 1995 and 2004, the smear-positive case notification rate increased from 45 to 143 per 100,000 population, the case detection rate from 22% to 45%, and the treatment success rate from 53% to 85%. The default and failure rates decreased from 26% to 6% and from 7% to 1%, respectively. There was a steady increase in the treatment success rate with the decentralisation of DOTS. Although 94% coverage was achieved after 10 years, the stepwise scale-up was important in securing resources and dealing with challenges. The programme achieved 85% treatment success; however, with the current low case detection rate (45%), the 70% WHO target seems unachievable in the absence of alternative case-finding mechanisms.

  13. Gender, internet experience, Internet identification, and internet anxiety: a ten-year followup.

    Science.gov (United States)

    Joiner, Richard; Gavin, Jeff; Brosnan, Mark; Cromby, John; Gregory, Helen; Guiller, Jane; Maras, Pam; Moon, Amy

    2012-07-01

    In 2002, we found gender differences in the use of the Internet. Since then, however, the Internet has changed considerably. We therefore conducted a follow-up study in 2012. The study involved 501 students (389 females and 100 males, 12 participants unspecified gender) and we measured Internet use, Internet anxiety, and Internet identification. We found that males had a greater breadth of Internet use; they used the Internet more for games and entertainment than females. The differentiation between males and females in terms of Internet use is evident, and in some ways is even more distinct than 10 years ago. In our previous research we had found no gender differences in the use of the Internet for communication, whereas in the current study we have found that females use the Internet for communication than males and were using social network sites more than males. We also found, consistent with our previous study, that Internet identification and Internet anxiety were related to Internet use.

  14. External genitalia gunshot wounds: a ten-year experience with fifty-six cases.

    Science.gov (United States)

    Brandes, S B; Buckman, R F; Chelsky, M J; Hanno, P M

    1995-08-01

    To determine the appropriate methods for the diagnosis and management of gunshot injuries to the external genitalia. Retrospective analysis. Fifty-six patients with gunshot wounds (GSWs) to the external genitalia were seen over the last 10 years. All patients underwent physical examination, radiographic staging, and surgical exploration, according to protocol. There were 25 testicular, 19 scrotal soft tissue, 14 penile, 4 epididymal, 4 urethral, 4 vasal, and 3 superficial scrotal skin injuries. When possible, all injuries, except for the vasal and 1 urethral injury, were primarily repaired with excellent long-term results. Orchiectomy was required in half of testes struck by gunshots. Associated injuries with single GSWs were mostly to the proximity soft tissue and were amenable to conservative management. Major associated injuries were present in patients with multiple GSWs. In the absence of a suspected major associated injury, genital GSWs required only two diagnostic studies, a retrograde urethrogram for suspected urethral injury and a routine abdominal radiograph. Gunshot injuries to the penis or perineum, blood at the penile meatus, or gross hematuria were highly suggestive of urethral injury. Successful management of genital GSWs is dependent upon prompt surgical exploration, conservative debridement, and primary repair.

  15. Acute health problems in African refugees: ten years' experience in a Swiss emergency department.

    Science.gov (United States)

    Pfortmueller, Carmen A; Graf, Fabienne; Tabbara, Malek; Tabarra, Malek; Lindner, Gregor; Zimmermann, Heinz; Exadaktylos, Aristomenis K

    2012-09-01

    Over the last two decades, the total number of applications from Africans for asylum in the countries of the European Union has increased from 578,000 to more than 2.9 million. About 20 % (7,196/36,100) of the asylum seekers in Switzerland originate from Africa. The disease profile of African asylum seekers is remarkably different from that of the native population in the country of application. We have therefore conducted an analysis of African asylum seekers presenting themselves to our emergency department. In a retrospective analysis, the central patient registry database was searched for patients originating from Africa admitted from 1 January 2000 to 30 November 2011 and labelled as "Asylbewerber" (asylum seeker) or "Flüchtling" (refugee). Three thousand six hundred and seventy-five African asylum seekers were admitted to our emergency department between 2000 and 2010. Thirty-four percent (n = 1,247) were female and 66 % (n = 2,426) male. Eighty percent (n = 1,940) of the men and 70 % (n = 823) of the women were younger than 40 years. Most of our patients originated from Algeria (n = 612). Forty-five percent (n = 1,628) of all patients presented with internal medical problems, 40 % (n = 1,487) with injuries. 3.5 % (n = 130) of all patients presented with psychiatric problems. Admission for psychiatric problems increased steadily from 2 % (n = 4) in 2001 to 10 % (n = 35) in 2011. The causes of presentation are manifold, including internal medical problems and injuries. Admissions for psychiatric problems are increasing. Establishing simple screening scores for somatization should be a key priority in providing more focused treatment in emergency departments.

  16. Ten Thousand Years of Solitude

    Energy Technology Data Exchange (ETDEWEB)

    Benford, G. (Los Alamos National Lab., NM (USA) California Univ., Irvine, CA (USA). Dept. of Physics); Kirkwood, C.W. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA). Coll. of Business Administration); Harry, O. (Los Alamos National Lab., NM (USA)); Pasqualetti, M.J. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA))

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs.

  17. Lessons from the Institute for New Heads (INH) Class of 2006: Ten Headships--134 Years of Hard-Earned Experience

    Science.gov (United States)

    Raphel, Annette; Huber, John; Chandler, Carolyn; Vorenberg, Amy; Jones-Wilkins, Andy; Devey, Mark A.; Holford, Josie; Craig, Ian; Elam, Julie

    2016-01-01

    Ten years ago in July 2006, 64 mostly starry-eyed men and women attended the NAIS Institute for New Heads (INH) in order to learn the ropes of headship. These newly minted heads were filled with enthusiasm, commitment, and passion, along with humility and a bit of healthy trepidation. One core group connected under the careful guidance of…

  18. [Transrectal ultrasound-guided prostatic biopsy: contribution of an ultrasound diagnostic unit after ten years of experience].

    Science.gov (United States)

    Rodríguez-Patrón Rodríguez, Rafael; Mayayo Dehesa, Teodoro; García González, Ricardo; Arias Fúnez, Fernándo; Lennie Zuccarino, Alberto; Sanz Mayayo, Enrique

    2006-05-01

    Although transrectal ultrasound-guided (TRUS) prostatic biopsy is the procedure of choice for the diagnosis of prostate cancer (PC), neither the ideal number of cores nor the number of repeated biopsies, nor the required diagnostic yield have been established. After our experience of ten years with TRUS biopsy we perform a review of the technique and its indications. PSA, ultrasound features, and pathologic data of 6000 patients undergoing modified sextant TRUS biopsy between 1994 to December 2002 were collected. 222 patients undergoing ten-core TRUS biopsy were included in an experimental group to study the role of the extended biopsy. The contribution of the extra cores to the diagnostic yield in the experimental group was studied to determine the effectiveness of the extended biopsy, using as a control group 552 patients undergoing sextant TRUS biopsy during 2002. Both groups were comparable for the study variables at the start of the study. The incidence of PC in the first biopsy in the group of 6000 patients was 39.1% (2345/6000). Patients with PSA between 4 and 10 ng/ml have an incidence of PC greater than 50% among prostates smaller than 20 cc, diminishing down to 8.9% in those greater than 50 cc. The percentage of PC among patients with negative digital rectal examination (DRE), normal TRUS, and PSA below 4 ng/ml was 16.7%. The diagnostic yield for PSA density lower than 0.11 ng/ml/cc was lower than 8%. The free/total PSA ratio shows a 13.7% incidence of PC with values higher than 0.24. Multivariate logistic regression analysis showed that the only non-significant parameter was free/total PSA. Sixty (27.15%) patients of the extended TRUS biopsy group had PC. Only 2.25% of the 221 patients benefited from the augmented number of biopsies. There were no significant differences in the figures of prostate cancer between groups. Only PSA and volume where significant in the multivariate logistic regression analysis; number of samples, PSA density and age lacked of

  19. The Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Project: Overview and results from ten years of ACE operations

    Science.gov (United States)

    Walker, Kaley; Strong, Kimberly

    2014-05-01

    As of February 2014, the Canadian-led Atmospheric Chemistry Experiment (ACE) satellite mission has been making measurements of the Earth's atmosphere for ten years. As ACE operations have extended beyond the initial two-year mission, there is a continuing need to validate the trace gas data products from the ACE-Fourier Transform Spectrometer (ACE-FTS) and the Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation (ACE-MAESTRO) instruments. Ground-based measurements provide critical data for the validation of satellite retrievals of trace gases and for the assessment of long-term stability of these measurements. In particular, validation comparisons are needed for ACE during Arctic springtime to understand better the measurements of species involved in stratospheric ozone chemistry. To this end, eleven Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Campaigns have been conducted during the spring period (February - April in 2004 - 2014) at the Polar Environment Atmospheric Research Laboratory (PEARL) in Eureka, Nunavut (80°N, 86°W). This period coincides with the most chemically active time of year in the Arctic, as well as a significant number of satellite overpasses. A suite of as many as 12 ground-based instruments, as well as frequent balloon-borne ozonesonde and radiosonde launches, have been used in each campaign. These instruments include: a ground-based version of the ACE-FTS (PARIS - Portable Atmospheric Research Interferometric Spectrometer), a terrestrial version of the ACE-MAESTRO, a SunPhotoSpectrometer, two zenith-viewing UV-visible grating spectrometers, a Bomem DA8 Fourier transform spectrometer, a Bruker 125HR Fourier transform spectrometer, a Systeme d'Analyse par Observations Zenithales (SAOZ) instrument, and several Brewer spectrophotometers. In the past several years, these results have been used to validate the measurements by the ACE-FTS and ACE-MAESTRO instruments on SCISAT as well

  20. Problem-based learning outcomes: ten years of experience at the University of Missouri-Columbia School of Medicine.

    Science.gov (United States)

    Hoffman, Kimberly; Hosokawa, Michael; Blake, Robert; Headrick, Linda; Johnson, Gina

    2006-07-01

    To add to a previous publication from the University of Missouri-Columbia School of Medicine (UMCSOM) on students' improvement in United States Medical Licensing Examination (USMLE) Step 1 and Step 2 scores after the implementation of a problem-based learning (PBL) curriculum by studying the performance of ten PBL class cohorts at the UMCSOM. Characteristics of graduating classes matriculating in both traditional and PBL curricula, 1993-2006, were compared for Medical College Admission Test component scores, undergraduate grade point averages, performance on the USMLE Step 1 and Step 2 exams, faculty contact hours, and residency directors' evaluations of UMCSOM graduates' performance in the first year of residency. Mean scores of six of the ten comparisons for USMLE Step 1 and six of nine comparisons for USMLE Step 2 are significantly higher (p academically advantaged students, increased time on task, or reduced class size. Gains in performance continue into residency, as evidenced by program directors' perceptions of superior performance of UMCSOM PBL graduates. The PBL curricular changes implemented with the graduating class of 1997 resulted in higher performances on USMLEs and improved evaluations from residency program directors. These changes better prepare graduates with knowledge and skills needed to practice within a complex health care system. Outcomes reported here support the investment of financial and human resources in our PBL curriculum.

  1. Ten years' of experience in patient education of families with a child/adolescent suffering from cystic fibrosis

    DEFF Research Database (Denmark)

    Bregnballe, Vibeke

    2007-01-01

    of six lessons of 3−4 hours every second month in one year. For the 5-year-olds it is three lessons of three hours in three successive months. For the parents with newly diagnosed children we have meetings three times a year. The CF school is rooted in practice and experiences. Two books have been made...... – one for the 10-year-olds and one for the 14-year-olds. The books are in Danish. The CF school is changed and developed continually to meet the needs of patients and relatives. Results: All patients attached to the CF Centre West in Denmark and born in 1985 or later have been or will be given the offer...

  2. Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Ayman A Al-Talib

    2016-01-01

    Full Text Available Objectives: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. Materials and Methods: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient′s age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation. Data was entered and analyzed using Excel; frequency distribution for categorical variables and descriptive statistics for continuous variables were computed. Results: Of a total of 25,000 deliveries in ten years, 22 cases of complete molar pregnancy were encountered: 0.9 cases of molar pregnancy per 1000 pregnancies. Majority of patients (63.7% were older than 35 years, and were nulliparous (45.5%. The commonest symptom was vaginal bleeding (86.4% followed by hyperemesis gravidarum (41.0%; Hyperthyroidism was seen in 1 patient (4.5%. Ovarian enlargement by theca-lutin cyst was seen in 3 patients (13.6%. The majority of patients (63.6% had normal BhCG within 9 weeks (63 days after suction curettage. The majority of the cases followed a benign course. Conclusion: Aged older than 35 years seems a risk factor and vaginal bleeding is the commonest presenting symptom. Early booking of pregnant women to antenatal care clinics and routine first trimester ultrasound made diagnosis easier and earlier before complications appear.

  3. [Ten years experience with the first approved biosimilar recombinant human growth hormone drug in normal clinical practice].

    Science.gov (United States)

    López-Siguero, Juan Pedro; Palla García, Margarida; Martínez Busto, Elena; Rebollo, Francisco José; Pombo, Manuel

    2017-06-28

    Recombinant human growth hormone (rhGH) is the first biosimilar drug approved by the European Medicines Agency in 2006, using the biosimilar registration process. It was authorised for the treatment of growth hormone deficiency, and growth disorders associated with Turner's syndrome, chronic renal failure, Prader-Willi syndrome, and growth disorders in children/adolescents born small for gestational age, and replacement therapy in adults with pronounced growth hormone deficiency. This review is focused on the scientific evidence published about this drug in the last ten years, including the clinical trials on which the approval of the regulatory authority is based, and the most relevant studies evaluating the clinical impact of the drug in clinical practice. The equivalence between biosimilar and original product has been confirmed in the clinical trials published by Romer et al. and López-Siguero et al. Furthermore, studies carried out in real-life conditions confirm its long-term efficacy and safety, as well as the absence of clinical impact by switching treatment from the original to the biosimilar product. The number of patients receiving this medication has continuously increased since its approval. Its equivalence with the original product has been verified. Preliminary data from the post-authorisation PATRO study confirm the efficacy and safety of the biosimilar product in comparison with data from clinical trials. However, final results must be evaluated at the end of the study, which will provide additional information about the long-term efficacy and safety of the biosimilar drug. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  4. The Ten Most Beautiful Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, George [The New York Times

    2010-10-20

    "Science in the 21st century has become industrialized. The experiments so often celebrated in the newspapers - sequencing the genome, proving the existence of the top quark, discovering a new planet by analyzing the wobble of a distant start - cost millions of dollars. They generate terabytes of data to be analyzed by supercomputers, calculating factories that spew out so much heat that they are equipped with cooling stacks and consume the energy of a small town. The experiments are carried out by research teams that have grown to the size of small corporations. But until very recently the most earth-shaking science came from individual pairs of hands. From a single mind confronting the unknown. The great experiments that mark the edges of our understanding were most often performed by one or two scientists and usually on a tabletop. Computation, if there was any, was carried out on paper or later with a slide rule. These experiments were designed and conducted with such straightforward elegance that they deserve to be called beautiful." (excerpt from the slide presentation accompanying the video)

  5. Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia

    Directory of Open Access Journals (Sweden)

    Allen Henrietta

    2011-08-01

    Full Text Available Abstract Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combination therapy (ACT and others are already facing parasites resistant to artemisinins. In this context, there is a crucial need to improve both access to and targeting of ACT through greater availability of good quality ACT and parasitological diagnosis. This is an issue of increasing urgency notably in the private commercial sector, which, in many countries, plays an important role in the provision of malaria treatment. The Affordable Medicines Facility for malaria (AMFm is a recent initiative that aims to increase the provision of affordable ACT in public, private and NGO sectors through a manufacturer-level subsidy. However, to date, there is little documented experience in the programmatic implementation of subsidized ACT in the private sector. Cambodia is in the unique position of having more than 10 years of experience not only in implementing subsidized ACT, but also rapid diagnostic tests (RDT as part of a nationwide social marketing programme. The programme includes behaviour change communication and the training of private providers as well as the sale and distribution of Malarine, the recommended ACT, and Malacheck, the RDT. This paper describes and evaluates this experience by drawing on the results of household and provider surveys conducted since the start of the programme. The available evidence suggests that providers' and consumers' awareness of Malarine increased rapidly, but that of Malacheck much less so. In addition, improvements in ACT and RDT availability and uptake were relatively slow, particularly in more remote areas. The lack of standardization in the survey methods and the gaps in the data highlight the importance of establishing a clear system for monitoring and evaluation for similar initiatives

  6. Ten years of clinical trial registration in a resource-limited setting: Experience of the Sri Lanka clinical trials registry.

    Science.gov (United States)

    Ranawaka, Udaya K; de Abrew, Ashwini; Wimalachandra, Manu; Samaranayake, Nithushi; Goonaratna, Colvin

    2018-02-01

    We describe our experience of the first 10 years at the Sri Lanka Clinical Trials Registry (SLCTR). We analyzed all trial records of the SLCTR over the study period. We collected information regarding trial characteristics and completeness of data entry in the SLCTR data set. During the study period, 210 trials (63% of all applications) were registered with the SLCTR. The number of registered trials showed an increasing trend over the years. All trial registrations had complete entries for all the data fields studied. Only 17.6% of the trials were registered retrospectively. All the registered trials were interventional studies, and the majority (87.6%) were randomized controlled trials. A significant proportion of trials (28.6%) were on noncommunicable diseases, and 12.4% were on pregnancy and its outcomes. Several trials (9.5%) were international collaborative studies. A majority of the Principal Investigators (70.9%) were affiliated to a university. Most of the studies (41.9%) were self-funded by the investigators. Details of ethics review committee approval were available for 96.7% of registered trials. Over a third of the registered trials (37.1%) had completed recruitment at the time of analysis. A majority of the trials (72.8%) had updated trial data since registration. There is a steady increase in the number of trials registered at the SLCTR. Complete entries for all the data fields were seen in all trial registrations. The SLCTR has made a positive contribution to the emergence of a healthy clinical research environment in Sri Lanka. © 2018 Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd.

  7. [Peer review procedures in pathology - more than ten years of experience in the free state of Saxony].

    Science.gov (United States)

    Eberlein-Gonska, Maria; Baretton, Gustavo; Habeck, Jörg-Olaf

    2012-01-01

    The positive experiences regarding peer review practice go back to the 1990s and can be traced in the position paper of the German Medical Association concerning quality assurance in the field of pathology. This evolved into the initiative of pathologists in Saxony to implement the peer review practice within the remit of their State Medical Association. Since the 14(th) of May 1999 various institutes as well as medical group practices in pathology and cytology have joined forces to undertake voluntary inter-institutional quality control measures. The aim was to improve the process and especially the outcome quality by reviewing each other's quality (analysing samples) on the basis of defined criteria. A positive review outcome report, which will have to be unanimously agreed upon by all participants, will lead to a positive recommendation for a certificate issued by the Medical Association of Saxony. Between 1999 and 2011 a total of 56 peer review proceedings took place. The potentials for improvement concern the problem of "kitchen pathology" still being used in the context of macroscopic description, the quality of microscopic description including the use of correct nomenclature, the quality of tumour classification and immune histological investigations. Statements concerning the advantage of the peer review method in particular refer to the integration of resident pathologists. Due to the long period of implementation of the peer review system und the small number of proceedings, it is not possible to come to a clear conclusion about the improvement or deterioration of quality. During a period of more than 10 years three peer review proceedings were not successful. In this situation, it is appropriate to ask the question of how restrictive peer reviews should be. The three most important aspects for the pathologists in Saxony are: self-determination, learning from each other, and a commitment to quality improvement. So this method set an example of how a

  8. Ten-year experiences with Tracheostomy at a University teaching hospital in Northwestern Tanzania: A retrospective review of 214 cases

    Directory of Open Access Journals (Sweden)

    Gilyoma Japhet M

    2011-11-01

    Full Text Available Abstract Background Tracheostomy remains a very important life saving surgical procedure worldwide and particularly in our environment where patients present late in upper airway obstruction. Little work has been done on this subject in our environment and therefore it was necessary to conduct this study to describe our own experiences with tracheostomy, outlining the common indications and outcome of tracheostomized patients in our setting and compare our results with those from other centers in the world. Methods This was a 10-year retrospective study which was conducted at Bugando Medical Centre from January 2001 to December 2010. Data were retrieved from patients' files kept in the Medical record department and analyzed using SPSS computer software version 15.0. Ethical approval to conduct the study was obtained from relevant authority before the commencement of the study. Results A total of 214 patients were studied. The male to female ratio was 3.1: 1. The majority of patients were in the 3rd decade of life. The most common indication for tracheostomy was upper airway obstruction secondary to traumatic causes in 55.1% of patients, followed by upper airway obstruction due to neoplastic causes in 39.3% of cases. The majority of tracheostomies (80.4% were performed as an emergency. Transverse skin crease incision was employed in all the cases. Post-tracheostomy complication rate was 21.5%. Complication rate was significantly higher in emergency tracheostomy than in electives (P Conclusion Upper airway obstruction secondary to trauma and laryngeal tumors still remains the most common indication for tracheostomy in our centre and tracheostomy is still a life saving procedure in the surgical management of airway despite complications which are seen more commonly in paediatric patients. Most of tracheostomy related complications can be avoided by meticulous attention to the details of the technique and postoperative tracheostomy care by skilled

  9. Acinar cell cystadenoma of the pancreas: A retrospective analysis of ten-year experience from a single academic institution.

    Science.gov (United States)

    Wang, Gang; Ji, Liang; Qu, Feng-Zhi; Li, Le; Cao, Cheng-Liang; Li, Zong-Bei; Zhu, Hong; Sun, Bei

    2016-01-01

    Acinar cell cystadenoma (ACA), also referred to as "acinar cystic transformation", is a rare and newly recognized cystic lesion of the pancreas displaying apparent acinar cell differentiation with benign outcomes. We summarized our experience with the diagnosis, clinicopathologic feature, treatment and prognosis of ACA to provide a reference for the disposal of this uncommon condition. We retrospectively analyzed the clinical data from eight patients with ACA treated in our hospital between March, 2005 and January, 2015. Among eight patients, five of whom were female and the age at diagnosis ranged from 33 to 67 years (mean, 49.8 y). The most commonly clinical symptom was abdominal pain. Eight lesions were unifocal and either unilocular (n = 5) or multilocular (n = 3) with average size of 10.5 cm (range, 5.1-19.7 cm). All the patients were treated surgically and a definite diagnosis of ACA was obtained by the histopathological, histochemical and immunohistochemical tests. The length of stay range was from 11 to 17 days and there were no perioperative deaths. At a median follow-up of 57.3 months, all the patients were alive and there was no evidence of recurrence, distant metastasis or malignant transformation. Appropriately preoperative differential diagnosis of ACA remains challenging and the final result is usually gained by the histopathology and immunohistochemistry. Although the origin of ACA is still contradictory, surgery is actively advocated as the most effective method for relieving the symptoms and preventing the tumor from local extension or malignant transformation so as to obtain an optimal long-term survival. Copyright © 2016 IAP and EPC. Published by Elsevier B.V. All rights reserved.

  10. Ten-year single-center experience of the ketogenic diet: factors influencing efficacy, tolerability, and compliance.

    Science.gov (United States)

    Wibisono, Cinthya; Rowe, Natalie; Beavis, Erin; Kepreotes, Helen; Mackie, Fiona E; Lawson, John A; Cardamone, Michael

    2015-04-01

    To evaluate the efficacy, tolerability, and compliance of 3 ketogenic diets, the classical ketogenic diet, medium-chain triglyceride (MCT), and modified Atkins diet. A single-center, retrospective study of 48 children with intractable epilepsy receiving ketogenic diets from 2003 to 2012. Patient demographics, epilepsy history, nutritional management, and side effects were collated. Compliance and tolerability were assessed by recording reasons for diet modification and cessation. The value of potassium citrate supplementation for preventing nephrolithiasis was reviewed. Median age at ketogenic diet initiation was 3.8 years (IQR: 2.3-7 years). The majority had intractable epilepsy, and 33 of the 48 children (69%) had epileptic encephalopathies. Three (6%) patients became seizure free, 35 (73%) reported Diet duration or ketogenic diet type did not predict reduction in seizures (P = .381; P = .272). Constipation (n = 31, 65%) was very common. Food refusal (n = 3, 6%) and poor parental compliance (n = 5, 10%) were common reasons cited for cessation. There were lower rates of side effects for modified Atkins diet. Diet cessation was greatest for MCT; however, 3 patients on MCT ceased therapy because adequate seizure control was achieved. Nephrolithiasis was reported in 1 patient before potassium citrate was used and 2 patients noncompliant with potassium citrate supplementation developed hypercalciuria. The 3 ketogenic diets were comparably effective in seizure control and generally well-tolerated. Potassium citrate supplementation is an effective prophylactic supplement for the prevention of nephrolithiasis. Crown Copyright © 2015. Published by Elsevier Inc. All rights reserved.

  11. [Systematic EDP-supported acquisition of follow-up data of keratoplasty patients--report on ten years' experience].

    Science.gov (United States)

    Böhringer, Daniel; Reinhard, Thomas; Sundmacher, Rainer

    2003-04-01

    Influencing factors on medium-term and long-term clear graft survival following penetrating keratoplasty are mostly basically known but their quantitative importance and interaction are far less well established. Due to abundance and complex interaction of influencing factors, comprehensive collection of pre- and postoperative data is imperative. Furthermore, application of stringent quality control as addressed in the German transplantation law established in 1997 is only possible if comprehensive data are available within a database system. All data from corneas preserved at the Lions cornea bank NRW as well as donor and follow-up data are entered into a custom-relational database system. This system implements management of data concerning the waiting list, the donors, organ culture as well as surgical and follow-up data. In order to demonstrate analysis of these data, 5-year graft survival with respect to preoperative risk assessment is analysed. Data of 1710 donors and 3333 recipients have been entered into the system so far. Clear graft survival 5 years after normal risk keratoplasty is 85 %, whereas prognosis of high-risk cases is significantly worse (history of ocular herpes simplex virus keratitis: 80 %, increased risk of graft rejection as the only risk factor: 65 %, glaucoma: 45 %, limbal stem cell insufficiency: 30 %; p < 0.05; log-rank test). The database system has proved indispensable for documentation, quality control and research. The implementation of this system is possible at any cornea bank. A common relational database system for cornea banks would of the banks as well as multicentre keratoplasty studies.

  12. Ten years experience of directly observed treatment short-course (dots) therapy for tuberculosis in Addis Ababa, Ethiopia.

    Science.gov (United States)

    Woldeyohannes, Desalegn; Kebede, Nigatu; Erku, Woldaregay; Tadesse, Zerihun

    2011-07-01

    Tuberculosis (TB) is still the leading cause of death worldwide accounting for 2.5% of the global burden of disease and 25% of all avoidable deaths in developing countries. The aim of the study was to evaluate the impact of the Directly Observed Treatment-Short course (DOTS) programme in Addis Ababa, Ethiopia from 1998-2007. Institutional-based retrospective study was employed Reports using world health organization (WHO) format for TB case finding and treatment outcome from all Sub-cities of the city to the Federal Ministry of Health were collected Between the years (1998-2007), 133,340 patients with all form of TB were registered. Of these, 40,929 (31%) were AFB + ve Pulmonary TB (PTB+ve), 48,491 (36%) were AFB-ve Pulmonary TB (PTB-ve), and 43,920 (33%) were Extra Pulmonary TB (EPTB) cases. The trend of case detection rate (CDR) for new smear positive pulmonary TB cases has increased from 73% in 1998 to its peak 113% in 2000 and then it decreased to 68% in 2007. The treatment success rate (TSR) has value with an average and standard deviation of 80% and 3.2, respectively from 1999 to 2007. It is possible to achieve the recommended WHO target (70% CDR & 85% TSR) as can be seen how closely these targets were approached (68% & 81%, respectively) in the city in 2007; However, this requires seeking alternative case finding mechanisms.

  13. Directly Observed Treatment Short-course (DOTS) for tuberculosis control program in Gambella Regional State, Ethiopia: ten years experience.

    Science.gov (United States)

    Sisay, Solomon; Mengistu, Belete; Erku, Woldaregay; Woldeyohannes, Desalegn

    2014-01-20

    Tuberculosis is still the leading cause of illness in the world which accounted for 2.5% of the global burden of disease, and 25% of all avoidable deaths in developing countries. The aim of study was to assess impact of DOTS strategy on tuberculosis case finding and treatment outcome in Gambella Regional State, Ethiopia from 2003 up to 2012 and from 2002 up to 2011, respectively. Health facility-based retrospective study was conducted. Data were collected and reported in quarterly basis using WHO reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in all zones of the region to Federal Ministry of Health. A total of 10024 all form of TB cases had been registered between the periods from 2003 up to 2012. Of them, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760(27.5%) had extra-pulmonary TB. Case detection rate of smear-positive pulmonary TB had increased from 31.7% to 46.5% from the total TB cases and treatment success rate increased from 13% to 92% with average mean value of being 40.9% (SD = 0.1) and 55.7% (SD = 0.28), respectively for the specified year periods. Moreover, the average values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. It is possible to achieve the recommended WHO target which is 70% of CDR for smear-positive pulmonary TB, and 85% of TSR as it was already been fulfilled the targets for treatments more than 85% from 2009 up to 2011 in the region. However, it requires strong efforts to enhance case detection rate of 40.9% for smear-positive pulmonary TB through implementing alternative case finding strategies.

  14. Directly Observed Treatment Short-course (DOTS) for tuberculosis control program in Gambella Regional State, Ethiopia: ten years experience

    Science.gov (United States)

    2014-01-01

    Background Tuberculosis is still the leading cause of illness in the world which accounted for 2.5% of the global burden of disease, and 25% of all avoidable deaths in developing countries. The aim of study was to assess impact of DOTS strategy on tuberculosis case finding and treatment outcome in Gambella Regional State, Ethiopia from 2003 up to 2012 and from 2002 up to 2011, respectively. Methods Health facility-based retrospective study was conducted. Data were collected and reported in quarterly basis using WHO reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in all zones of the region to Federal Ministry of Health. Results A total of 10024 all form of TB cases had been registered between the periods from 2003 up to 2012. Of them, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760(27.5%) had extra-pulmonary TB. Case detection rate of smear-positive pulmonary TB had increased from 31.7% to 46.5% from the total TB cases and treatment success rate increased from 13% to 92% with average mean value of being 40.9% (SD = 0.1) and 55.7% (SD = 0.28), respectively for the specified year periods. Moreover, the average values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. Conclusion It is possible to achieve the recommended WHO target which is 70% of CDR for smear-positive pulmonary TB, and 85% of TSR as it was already been fulfilled the targets for treatments more than 85% from 2009 up to 2011 in the region. However, it requires strong efforts to enhance case detection rate of 40.9% for smear-positive pulmonary TB through implementing alternative case finding strategies. PMID:24444379

  15. Ten-year urban forestry action plan

    Science.gov (United States)

    J.W." Jerry" Van Sambeek

    2017-01-01

    The Ten-year Urban Forestry Action Plan: 2016-2026 was published in September, 2015 (see http://www.urbanforestry.subr.edu/FinalActionPlan_Complete_11_17_15.pdf). This 260 page heavily illustrated document was prepared by the National Urban and Community Forestry Advisory Council (NUCFAC) under leadership and funding from the USDA Forest Service. The Plan's...

  16. Czech, Slovak science ten years after split

    CERN Multimedia

    2003-01-01

    Ten years after the split of Czechoslovakia Czech and Slovak science are facing the same difficulties: shortage of money for research, poor salaries, obsolete equipment and brain drain, especially of the young, according to a feature in the Daily Lidove Noviny (1 page).

  17. Advancing the education in molecular diagnostics: the IFCC-Initiative "Clinical Molecular Biology Curriculum" (C-CMBC); a ten-year experience.

    Science.gov (United States)

    Lianidou, Evi; Ahmad-Nejad, Parviz; Ferreira-Gonzalez, Andrea; Izuhara, Kenji; Cremonesi, Laura; Schroeder, Maria-Eugenia; Richter, Karin; Ferrari, Maurizio; Neumaier, Michael

    2014-09-25

    Molecular techniques are becoming commonplace in the diagnostic laboratory. Their applications influence all major phases of laboratory medicine including predisposition/genetic risk, primary diagnosis, therapy stratification and prognosis. Readily available laboratory hardware and wetware (i.e. consumables and reagents) foster rapid dissemination to countries that are just establishing molecular testing programs. Appropriate skill levels extending beyond the technical procedure are required for analytical and diagnostic proficiency that is mandatory in molecular genetic testing. An international committee (C-CMBC) of the International Federation for Clinical Chemistry (IFCC) was established to disseminate skills in molecular genetic testing in member countries embarking on the respective techniques. We report the ten-year experience with different teaching and workshop formats for beginners in molecular diagnostics. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. The influencing factors in the business environment of the Visegrád Group in the last ten years and their comparison to Russia's experience

    Directory of Open Access Journals (Sweden)

    Ilya Igorevich Bolotov

    2015-09-01

    Full Text Available Objective examination of development of the business environment in the Central and Eastern European Visegraacuted Group Czech Republic Slovak Republic Poland and Hungary in the last ten years 2004ndash2014 by determining its influencing factors and comparison of the results with the experience of the Russian Federation. Methods approximation of the business environment with the help of five businessentity oriented indicators and analysis of relationship between them and their influencing factors i.e. areas of competitiveness in the definition of the Heritage Foundation based on correlation analysis time series cointegration model and a specific panel cointegration model. Research results the characteristic feature of the business environment in the Visegraacuted Group was adapting to integration into regional and global value chains. The main influencing factors of these changes were fiscal trade and investment freedoms to a lesser extent ndash freedom from corruption as well as membership in the European Union. The development in the Russian Federation was focused on concentration of business activities improving all indicators of the business environment and being caused by third factors. Scientific novelty first major complex study on the business environment in the Visegraacuted Group and in Russia published in the Russian Federation. Practical value better insight in the development of the business environment in the Central and Eastern European economies and in Russia which can be used in macroeconomic policies of the Russian Federation. nbsp

  19. BIFoR FACE: A ten-year Free-Air Carbon Dioxide Enrichment (FACE) Experiment in Old Growth Deciduous English Woodland

    Science.gov (United States)

    Thomas, R. M.; MacKenzie, A. R.; Ellsworth, D.; Hemming, D.; Crous, K.; Pope, F.; Blaen, P.; Poynter, A.; Hamilton, L.; Blenkhorn, D.; Jarvis-Rouse, F.

    2015-12-01

    The Birmingham Institute of Forest research (BIFoR) will perform fundamental physical, biological, ecological, social and cultural research of direct relevance to forested landscapes worldwide. A core platform for BIFoR to study the ten-year response of a mature temperate deciduous forest ecosystem to against a large step-change in atmospheric [CO2] is the BIFoR Free-Air Carbon Dioxide Enrichment (FACE) experiment. BIFoR FACE is being established in Mill Haft, a mature (~150 year-old) oak (Quercus robur) and hazel (Corylus avellana) coppice-with-standards woodland in central England. The facility will enable elevated CO2 (eCO2) treatments to be introduced in 30 m diameter rings (3 treatment and 6 control plots), commencing in spring 2016. Under eCO2 conditions primary research questions will investigate carbon uptake and storage, corresponding nutrient limitations, and biodiversity and ecosystem responses. As well as describing the facility and experimental design, we present baseline data collected throughout 2015, prior to fumigation. These data include: biophysical tree properties; atmospheric CO2/H2O fluxes; airborne and ground laser scatterometry; leaf area index; geophysical survey data; phenology camera derivatives; soil and water chemical and physical properties; and invertebrate surveys. Data from an intensive campaign conducted during august 2015 are also shown, including in- and above- canopy characterisation of biogenic VOCs using a Proton Transfer Reaction Mass Spectrometer, aerosol loading including bioaerosols, and enhanced atmospheric chemistry. Further campaign results are presented from leaf level photosynthetic carbon-dioxide response curve (A/Ci) performed at different canopy heights on oak trees, and on the dominant understory species - hazel and sycamore (Acer pseudoplatinus) across the site. BIFoR FACE is an exciting new international facility for forest science - ideas for collaborations are encouraged. Please see http

  20. Romania: Ten Years of EU Membership

    Directory of Open Access Journals (Sweden)

    Gábor Hunya

    2017-06-01

    Full Text Available By joining the European Union as of 1st of January 2007, Romania made use of a window of opportunity which may not have been open later. In the ten years that followed, advantages and challenges of the membership have in part been overshadowed by the impact of the global financial crisis. The country went through a boom-bust-boom economic cycle. The swing from overheating to depression and back again to overheating has been amplified by pro-cyclical economic policy. Romania has been a selective policy taker in the EU often delaying fiscal and legal actions resulting in lost benefits. By reviewing the current political uncertainties in Europe, the conclusion emerges that more effective governance and more active foreign policy is necessary under the current Europe-wide orientation loss. The country may need to develop a mobilising strategy and policy beyond the direct benefits provided by the EU, one that also contributes to the success of the European integration.

  1. The first ten years of Swift supernovae

    Science.gov (United States)

    Brown, Peter J.; Roming, Peter W. A.; Milne, Peter A.

    2015-09-01

    The Swift Gamma Ray Burst Explorer has proven to be an incredible platform for studying the multiwavelength properties of supernova explosions. In its first ten years, Swift has observed over three hundred supernovae. The ultraviolet observations reveal a complex diversity of behavior across supernova types and classes. Even amongst the standard candle type Ia supernovae, ultraviolet observations reveal distinct groups. When the UVOT data is combined with higher redshift optical data, the relative populations of these groups appear to change with redshift. Among core-collapse supernovae, Swift discovered the shock breakout of two supernovae and the Swift data show a diversity in the cooling phase of the shock breakout of supernovae discovered from the ground and promptly followed up with Swift. Swift observations have resulted in an incredible dataset of UV and X-ray data for comparison with high-redshift supernova observations and theoretical models. Swift's supernova program has the potential to dramatically improve our understanding of stellar life and death as well as the history of our universe.

  2. Ten years for the public Web

    CERN Multimedia

    2003-01-01

    Ten years ago, CERN issued a statement declaring that a little known piece of software called the World Wide Web was in the public domain. Nowadays, the Web is an indispensable part of modern communications. The idea for the Web goes back to March 1989 when CERN Computer scientist Tim Berners-Lee wrote a proposal for a 'Distributed Information Management System' for the high-energy physics community. The Web was originaly conceived and developed to meet the demand for information sharing between scientists working all over the world. There were many obstacles in the 1980s to the effective exchange of information. There was, for example a great variety of computer and network systems, with hardly any common features. The main purpose of the web was to allow scientists to access information from any source in a consistent and simple way. By Christmas 1990, Berners-Lee's idea had become the World Wide Web, with its first server and browser running at CERN. Through 1991, the Web spread to other particle physics ...

  3. Epidemiological Study of RRT-Treated ESRD in Nanjing - A Ten-Year Experience in Nearly Three Million Insurance Covered Population.

    Directory of Open Access Journals (Sweden)

    Yu-Chen Han

    Full Text Available The growing burden of end-stage renal disease (ESRD has been a great challenge to the health care system of China. However, the exact epidemiological data for ESRD in China remain unclear. We aimed to investigate the epidemiology of ESRD treated by renal replacement therapy (RRT in Nanjing based on analysing ten-year data of Nanjing three million insurance covered population.Using the electronic registry system of Urban Employee Basic Medical Insurance (UEBMI, we included all subjects insured by UEBMI in Nanjing from 2005 to 2014 and identified subjects who developed ESRD and started RRT in this cohort.The UEBMI population in Nanjing increased from 1,301,882 in 2005 to 2,921,065 in 2014, among which a total of 5,840 subjects developed ESRD and received RRT. Over the 10-year period, the adjusted incidence rates of RRT in the UEBMI cohort gradually decreased from 289.3pmp in 2005 to 218.8pmp in 2014. However, the adjusted prevalence rate increased steadily from 891.7pmp in 2005 to 1,228.6pmp in 2014. The adjusted annual mortality rate decreased from 138.4 per 1000 patient-years in 2005 to 97.8 per 1000 patient-years in 2014. The long-term survival rate fluctuated over the past decade, with the 1-year survival rate ranging from 85.1% to 91.7%, the 3-year survival rate from 69.9% to 78.3% and the 5-year survival rate from 58% to 65.4%.Nanjing is facing an increasing burden of ESRD with its improvement of medical reform. The ten-year complete registry data on RRT in urban employees in Nanjing provided a unique opportunity to understand the real threat of ESRD confronting China during its process of health care transition.

  4. Epidemiological Study of RRT-Treated ESRD in Nanjing - A Ten-Year Experience in Nearly Three Million Insurance Covered Population.

    Science.gov (United States)

    Han, Yu-Chen; Huang, Han-Ming; Sun, Ling; Tan, Chao-Ming; Gao, Min; Liu, Hong; Tang, Ri-Ning; Wang, Yan-Li; Wang, Bei; Ma, Kun-Ling; Liu, Bi-Cheng

    2016-01-01

    The growing burden of end-stage renal disease (ESRD) has been a great challenge to the health care system of China. However, the exact epidemiological data for ESRD in China remain unclear. We aimed to investigate the epidemiology of ESRD treated by renal replacement therapy (RRT) in Nanjing based on analysing ten-year data of Nanjing three million insurance covered population. Using the electronic registry system of Urban Employee Basic Medical Insurance (UEBMI), we included all subjects insured by UEBMI in Nanjing from 2005 to 2014 and identified subjects who developed ESRD and started RRT in this cohort. The UEBMI population in Nanjing increased from 1,301,882 in 2005 to 2,921,065 in 2014, among which a total of 5,840 subjects developed ESRD and received RRT. Over the 10-year period, the adjusted incidence rates of RRT in the UEBMI cohort gradually decreased from 289.3pmp in 2005 to 218.8pmp in 2014. However, the adjusted prevalence rate increased steadily from 891.7pmp in 2005 to 1,228.6pmp in 2014. The adjusted annual mortality rate decreased from 138.4 per 1000 patient-years in 2005 to 97.8 per 1000 patient-years in 2014. The long-term survival rate fluctuated over the past decade, with the 1-year survival rate ranging from 85.1% to 91.7%, the 3-year survival rate from 69.9% to 78.3% and the 5-year survival rate from 58% to 65.4%. Nanjing is facing an increasing burden of ESRD with its improvement of medical reform. The ten-year complete registry data on RRT in urban employees in Nanjing provided a unique opportunity to understand the real threat of ESRD confronting China during its process of health care transition.

  5. Ten years of SLR production in Argentina

    Science.gov (United States)

    Pacheco, A.; Podestá, R.; Yin, Z.; Liu, W.; Actis, E.; Adarvez, S.; Quinteros, J.; Podestá, F.

    2017-07-01

    SLR technique is a proved astro-geodetic art with a significant power to contribute to Earth and Space Sciences. Therefore, scientific applications of SLR System are able to perform multiple tasks in the fields of Astrometry, Geodesy and Geophysics. The results we show here were obtained from satellite observations made at SLR 7406 Station of Observatorio Astronómico Félix Aguilar (OAFA) in San Juan, Argentina. The telescope was installed early on 2006, in concordance with an International Cooperation Agreement between Universidad Nacional de San Juan, Argentina and Chinese Academy of Sciences. In this abstract we show the current research being done with ILRS 7406 station: Length of day (LOD) and Angular velocity of Earth Rotation, calculated weekly; Pole Motion. ILRS7406 is daily surveying Pole coordinates x and y; Tracking SLR to GNSS constellations. SLR System contributes to the adjustment and validation of satellite GALILEO, GPS, GLONASS, and BEIDOU orbits. Our station is nowadays member of the new ITRF 2014 frame, and these past years has been one of the 3 highest producing SLR Stations on the ILRS net, composed of about 40 stations distributed all around the world. The obtained results during this first 10 years of experience are useful to enhance the traditional collaboration between OAFA and international services such as ILRS, IERS and NASA.

  6. Ten years of CR physics with PAMELA

    Science.gov (United States)

    Galper, A.; Spillantini, P.

    2017-09-01

    The satellite borne Pamela instrument is dedicated to the precise and high statistics study of CR fluxes on a four decades energy range. Pamela experiment is the last step of the "Russian-Italian Mission" (RIM) program established in 1992 between several Italian and Russian institutes and with the participation of Sweden and Germany. Designed as a cosmic ray observatory at 1 AU, it extensive program is made possible thanks to the outstanding performance of the instrument, the low energy threshold, the quasi-polar orbit and the 10 years duration of the observation. The physics program pays particular attention to the study of particles and antiparticles fluxes and includes search for dark matter, primordial antimatter, new matter in the Universe, study of cosmic-ray propagation, solar physics and solar modulation, and terrestrial magnetosphere. Very important is the discovery of the anomalous increase of the positron flux at energies higher that 50 GeV (the so called "Pamela anomaly"), and the abrupt spectral hardening of H and He, challenging the current paradigm of cosmic-ray acceleration and propagation in the Galaxy.

  7. VOICE PROSTHESES – TEN YEARS AFTER

    Directory of Open Access Journals (Sweden)

    Igor Fajdiga

    2002-12-01

    Full Text Available Since the introduction of tracheoesophageal puncture method by Bloom and Singer in 1980, the success of restoring vocal communication in laryngectomees has improved significantly. At the University Department of Otorhinolaringology and Cervicofacial Surgery in Ljubljana, the method has been used since 1993. We have performed 76 secondary tracheoesophageal punctures in patients with no objective contraindications and with an interest for this method. The success rate was 92%. With regard to our 10-years experience, we wanted to (re define present and future role of tracheoesophageal voice/speech in the alaryngeal voice rehabilitation. To compare both alaryngeal speech modes, 32 patients using tracheoesophageal speech and 35 patients using esophageal speech were included into the study. In both groups the patients were established speakers. The complications that occurred in the patients with voice prostheses are presented. Most of them required only replacement of prostheses for their solution.The tracheoesophageal puncture and voice prosthesis insertion is a reliable and fast way of restoring good voice and speech after laryngectomy. In spite of some objective disadvantage in comparison to esophageal speech – like the use of hand, need for regular maintenance, and relying to medical service, its good characteristics should rank it immediately after a good esophageal speech. This means that tracheoesophageal voice prostheses should be offered to all patients, which are not able to learn a good esophageal voice in short time, to avoid a frustrating time with no vocal communication. After tracheoesophageal puncture and voice prosthesis insertion, the patient should still get a possibility to learn esophageal speech if he wants to avoid the drawbacks of the tracheoesophageal speech.

  8. The Consulting Teacher Program: Ten Years Later.

    Science.gov (United States)

    Perelman, Phyllis F.; And Others

    A program designed to train learning specialists called consulting teachers who, in turn, train classroom teachers to educate handicapped children in the regular classroom setting is described. Consulting teacher trainees are selected on the basis of teaching experience, leadership capability, academic promise, and commitment to special education.…

  9. An update in varicose vein pathology after ten years of endovenous laser therapy (EVLT) with a 980 nm diode laser: clinical experience of a single center.

    Science.gov (United States)

    Scarpelli, Pietro; Maggipinto, Annamaria; Leopardi, Marco; Di Marco, Evelina; Disabato, Angelo; Boschetti, Michelangelo; Sbenaglia, Giorgio; Spartera, Carlo; Ventura, Marco

    2013-12-30

    To show our experience in the surgical treatment of superficial vein insufficiency of the lower limbs. Since 2002 we have performed 659 procedures of endovascular laser therapy (EVLT) (group A) in the treatment of chronic venous insufficiency of the great saphenous vein using a 980 nm diode laser. A closely matched group of 100 patients (50 Group A, 50 Group B) with homogeneous clinical findings (CEAP classification) was controlled with a mean follow-up of 18 months in our more recent experience (3 years). Most patients operated on in this period were lost to follow-up. The Final results showed that EVLT can be used only in a specific selected group of cases based on anatomy and hemodynamics and while 980 nm EVLT could not be selected as the best treatment for this pathology, it could be placed side by side with conventional therapy. In our one year's more recent experience, we observed an increased number of patients treated with conventional therapy. The development of new laser tools (new wavelengths and continuous radial laser) and the improvement of clinical follow up may lead us to a more correct application of EVLT in the absence of randomized trials because of widespread clinical findings and poor pathological follow-up of this approach to superficial venous insufficiency.

  10. The Columbine Tragedy Ten Years Later

    Science.gov (United States)

    Hammond, Jane

    2009-01-01

    Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

  11. TEN YEARS OF "CONDENSED MATTER PHYSICS"

    OpenAIRE

    Editors

    2003-01-01

    This year the journal "Condensed Matter Physics" celebrates its tenth anniversary. It was founded in 1993 by the Institute for Condensed Matter Physics of the National Academy of Sciences of Ukraine for the purpose of publishing the regular and review papers in the field of statistical mechanics and condensed matter theory.

  12. Ovarian Kaleidoscope database: ten years and beyond.

    Science.gov (United States)

    Hsueh, Aaron J; Rauch, Rami

    2012-06-01

    Ovarian Kaleidoscope database (OKdb) is an online, searchable, public database containing text-based and DNA microarray data to facilitate research by ovarian researchers. Using key words and predetermined categories, users can search ovarian gene information based on gene function, cell type of expression, cellular localization, hormonal regulation, mutant phenotypes, chromosomal location, ligand-receptor relationship, and other criteria, either alone or in combination. For individual genes, users can access more than 10 extensive DNA microarray datasets to interrogate gene expression patterns in a development-specific and cell type-specific manner. All ligand and receptor genes expressed in the ovary are matched to facilitate investigation of paracrine/autocrine signaling. More than 3500 ovarian genes in the database are matched to 185 gene pathways in the Kyoto Encyclopedia of Genes and Genomes to allow for elucidation of gene interactions and relationships. In addition to >400 genes with infertility or subfertility phenotypes when mutated in mice or humans, the OKdb also lists ~50 and ~40 genes associated with polycystic ovarian syndrome and primary ovarian insufficiency, respectively. The expanding OKdb is updated weekly and allows submission of new genes by ovarian researchers to allow instant access to DNA microarray datasets for newly submitted genes. The present database is a virtual community for ovarian researchers and allows users to instantaneously provide their comments for individual gene pages based on an automated Web-discussion system. In the coming years, we will continue to add new features to serve the ovarian research community.

  13. Virgin galactic the first ten years

    CERN Document Server

    Seedhouse, Erik

    2015-01-01

    Thirty years ago when Sir Richard Branson called up Boeing and asked if they had a spare 747, few would have predicted the brash entrepreneur would so radically transform the placid business of air travel. But today, Branson flies airlines on six continents, employs hundreds of jets and, in 2014, was predicting that his spaceship company – Virgin Galactic – would soon open the space frontier to commercial astronauts, payload specialists, scientists and space tourists. With more than 600 seats sold at $250,000 each, what started off as a dream to send people just for the excitement to look back and marvel at Earth, was on the cusp of finally being turned into a business. Then, on October 21, 2014, tragedy struck. SpaceShipTwo was on its most ambitious test flight to date. Seconds after firing its engine, Virgin Galactic’s spaceship was breaking through the sound barrier. In just the three seconds that it took for the vehicle to climb from Mach 0.94 to Mach 1.02, co-pilot Mike Alsbury made what many close...

  14. Beijing--ten years after Mao.

    Science.gov (United States)

    1987-03-01

    10 years after Mao's death, Beijing is a different place; the average resident has more money to spend in a considerably freer marketplace, but still not a lot by Western standards. Clearly the biggest advertisers in China over the longest period, the Japanese sell more consumer products in China than any other country. The 1982 Chinese census placed the population of the municipality of Beijing at 9,230,687 people. Due mainly to the extensive development of heavy industry in Beijing and the creation of over 1 million jobs in this sector between 1949 and 1979, Beijing's population jumped to 8.7 million by 1979. Beijing's population will continue to grow despite its 1 child policy and drastically reduced fertility rates. A 1981 survey polling 8000 Beijing women found that the average age of 1st marriage and 1st childbirth is gradually rising while the interval between marriage and 1st childbirth is gradually rising while the interval between marriage and 1st birth is shortening. China's 1982 census indicates that 26% of city dwellers are under age 15, 21.6% between the ages of 15 and 24, 47.7% are between the ages of 25 and 64, and 4.7% 65 or over. As the burden shifts from supporting the dependent old, China will need to revamp its policies to alleviate the stress placed on Chinese families and to increase financial aid the elderly. In 1982, Beijing households averaged 3.9 persons per household, slightly lower than the 4.1. persons per urban household 1982 national figure. Demographic sources for China are listed and critiqued.

  15. Epidemiological analysis of tuberculosis in Ethiopia: A ten-year ...

    African Journals Online (AJOL)

    A time-series study design was applied to analyze the ten-year trends of Tuberculosis in Ethiopia. Data on ten-key indicators for the period of 2000-2009 was obtained from the Ministry of Health public documents. Five stratifying variables were used to analyze the trends in the key TB indicators. The data on the indicators ...

  16. [Description of assessment processes at the Medical School of the Pontificia Universidad Católica de Chile: a ten year experience].

    Science.gov (United States)

    Sánchez D, Ignacio; Riquelme P, Arnoldo; Moreno B, Rodrigo; Salas I, Sofía; Pertuzé R, Julio; García C, Patricia

    2010-08-01

    Globalization of health care seems to be irreversible and beyond cultural differences and local realities; consequently, medical education needs to have a common set of core principles or standards that may be applied worldwide. The aim of participating in assessment processes is to guarantee that medical education takes place in a sufficiently rich environment to promote extensive academic purposes. The Medical School of the Pontificia Universidad Católica de Chile (PUC) participated in three assessment processes that included three stages: internal assessment, external assessment, and accreditation judgment. Two of these assessments were voluntarily carried out following the standards set by the Liaison Committee on Medical Education-LCME, and they took place in 1997 and 2007. The other assessment was based on standards set by the Chilean accrediting organism, the National Committee for Undergraduate Program Accreditation (Comité Nacional de Acreditación de Pregrado-CNAP) and took place in the year 2001. In all three experiences, internal assessment was the most enriching stage, stimulating refections among students and teachers in order to recognize areas of strengths and weaknesses. External assessment processes, especially those based on international standards, are very important for the institutional and program development of Medical Schools. The PUC Medical School on its whole learnt how to carry out an assessment process and was able to improve several weaknesses without pressure, moving from quality assurance to quality enhancement. The present paper analyzes the major challenges involved in an external assessment process.

  17. Ten years of clinical experience in the use of fixed-pressure versus programmable valves: a retrospective study of 159 patients.

    Science.gov (United States)

    Mpakopoulou, Maria; Brotis, Alexandros G; Gatos, Haralampos; Paterakis, Konstantinos; Fountas, Kostas N

    2012-01-01

    The aim of this study was to present our 10-year experience with the use of fixed-pressure and programmable valves in the treatment of adult patients requiring cerebrospinal fluid (CSF) diversion. Patients (n = 159; 89 male and 70 female) suffering from hydrocephalus of various causes underwent CSF shunt implantation. Forty fixed-pressure and 119 programmable valves were initially implanted. The observed revision rate was 40% in patients with fixed-pressure valves. In 20% of these patients, a revision due to valve mechanism malfunction was undertaken, and the initial valve was replaced with a programmable one. The revision rate in the adjustable-pressure valve subgroup was 20%. The infection rate for the fixed-pressure and programmable valve subgroups were 3%, and 1.7%, respectively. Similarly, subdural fluid collections were noticed in 17% and 4% of patients with fixed-pressure valves and programmable valves, respectively. The revision and over-drainage rates were significantly lower when using programmable valves, and thus, this type of valve is preferred whenever CSF has to be diverted.

  18. Managing mountain hardwoods - a ten-year appraisal

    Science.gov (United States)

    George R., Jr. Trimble

    1961-01-01

    Ten years ago - in 1949 - four 5-acre plots were established on the Fernow Experimental Forest near Parsons, West Virginia, to show the effects upon mountain hardwoods of each of four management treatments.

  19. Using the Movie Awakenings (1990 to Evaluate Learningin the Biology Degree Program at the UniversitatPompeu Fabra. Ten Years of Experience

    Directory of Open Access Journals (Sweden)

    Jorge PÉREZ SÁNCHEZ

    2017-03-01

    Full Text Available This paper narrates the experience of using the movie Awakenings (1990 as an important basis for final assessment in a beginner’s course for biology students at the Universitat Pompeu Fabra. From the results obtained, both the evaluation of the course and the use of the film have been positive, supporting the use of commercial movies in university education.

  20. Allogeneic hematopoietic stem cells transplantation in acute leukemia: ten years of experience in the Hospital das Clínicas - UFMG

    OpenAIRE

    Lamego, Rosana M.; Clementino, Nelma C. D.; Costa, Ângela L. B.; Oliveira, Marçal J. M.; Bittencourt, Henrique

    2010-01-01

    As leucemias agudas são doenças com alta morbimortalidade para as quais o transplante alogênico de medula óssea é uma opção terapêutica eficaz. Neste artigo, relatamos a experiência de um centro brasileiro com pacientes apresentando leucemia aguda que receberam um enxerto de medula óssea ou células-tronco periféricas de um doador familiar HLA idêntico no período de julho de 1995 a dezembro de 2005. Foi realizado um estudo de coorte retrospectivo, analisando dados de 125 pacientes com mediana ...

  1. Ten years' experience of Directly Observed Treatment Short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program.

    Science.gov (United States)

    Sisay, Solomon; Mengistu, Belete; Erku, Woldargay; Woldeyohannes, Desalegne

    2016-12-01

    World Health Organization (WHO) declared tuberculosis (TB) as a global public health emergency and recommended DOTS as a standard strategy for controlling the disease. TB is one of the major causes of infectious diseases in the world, and 25% of all avoidable deaths in developing countries. About a third of the world's population is estimated to be infected with tubercle bacilli, and hence at risk of developing active disease. The objective of the study was, therefore, to evaluate the impact of DOTS strategy on smear-positive pulmonary tuberculosis case finding and their treatment outcomes in Gambella Regional State, Ethiopia. A retrospective health facility-based descriptive study was employed. Quarterly data were collected by using WHO structured reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in the region. A total of 10,024 TB cases (all forms) were registered and reported between the periods from 2003 up to 2012. Out of these, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760 (27.5%) had extra-pulmonary TB. An average case detection rate (CDR)(1) of 40.9% (SD=0.1) and treatment success rate (TSR)(2) of 55.7% (SD=0.28) for smear-positive pulmonary TB including other forms of TB were reported for the specified years period. Additionally, the average mean values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. The recommended TSR set by WHO was achieved as it was already been fulfilled more than 85% from 2009 up to 2011 in the region and the reported CDR was far below (40.9%) for smear-positive pulmonary TB including other forms of TB from the target. Therefore, extensive efforts should be established to maintain the achieved TSR and to increase the low level of CDR for all forms of TB cases through implementing alternative case finding strategies. Copyright © 2016.

  2. Closer to zero: Reflections on ten years of ART rollout

    African Journals Online (AJOL)

    To reflect upon ten years of antiretroviral therapy. (ART) rollout, one really should set the clock back a little further to see the massive impact of ART on our lives – for clinicians and patients alike. My own journey with HIV began in 1999 when, as a young doctor, I decided to venture into private practice with a local general ...

  3. A ten-year histopathological study of generalised lymphadenopathy ...

    African Journals Online (AJOL)

    2010-07-31

    Jul 31, 2010 ... Original Research: A ten-year histopathological study of generalised lymphadenopathy in India. 267. Vol 53 No 3. S Afr Fam Pract 2011. Introduction. The body contains approximately 600 lymph nodes, but only those in the submandibular, axillary and inguinal regions may be palpable in healthy people.

  4. Ten-year-olds' reflections on their life in preschool

    DEFF Research Database (Denmark)

    Broström, Stig

    2016-01-01

    What do children think of their time in preschool? In the present study, twelve ten-year-old children collected data from their classmates. The children tend to remember their friends, and reflect on what games they played and with whom. Only about one in three respondents even mentioned the day...

  5. Ten years into the marshes – Hapalemur alaotrensis conservation ...

    African Journals Online (AJOL)

    This article describes the approach that Madagascar Wildlife Conservation has been implementing during the past ten years at Lake Alaotra, discussing the plan of action and challenges for environmental education, ecotourism and alternative livelihoods. Les problèmes de gestion des ressources naturelles impliquent ...

  6. Changes in users' Web search performance after ten years ...

    African Journals Online (AJOL)

    The changes in users' Web search performance using search engines over ten years was investigated in this study. Matched data obtained from samples in 2000 and 2010 were used for the comparative analysis. The patterns of Web search engine use suggested a dominance in using a particular search engine. Statistical ...

  7. Ten Years after Columbine: The Tragedy of Youth Deepens

    Science.gov (United States)

    Giroux, Henry A.

    2009-01-01

    For young people it just gets worse. Ten years after the Columbine tragedy, the debate over school safety has clearly shown that educators, parents, politicians, and the mainstream media have created the conditions in which young people have increasingly become the victims of adult mistreatment, indifference, neglect, even violence. The tragic…

  8. The African Association for Lexicography: After Ten Years

    OpenAIRE

    Mariëtta Alberts

    2011-01-01

    ABSTRACT: This year it has been ten years since the establishment of AFRILEX. After an expla-nation of what led to its forming, this article gives a short overview of its composition and activi-ties.


    Keywords: AFRICAN ASSOCIATION FOR LEXICOGRAPHY (AFRILEX), AFRICAN LAN-GUAGES ASSOCIATION OF SOUTH AFRICA (ALASA), BUREAU OF THE WOORDEBOEK VAN DIE AFRIKAANSE TAAL (WAT), DICTIONARY OF SOUTH AFRICAN ENGLISH (DSAE), LINGUISTIC ASSOCIATION OF SOUTHERN AFRICA (L...

  9. The origin of the future ten questions for the next ten years

    CERN Document Server

    Gribbin, John

    2006-01-01

    How did the universe begin? Where do galaxies come from? How do stars and planets form? Where do the material particles we are made of come from? How did life begin? Today we have only provisional answers to such questions. But scientific progress will improve these answers dramatically over the next ten years, predicts John Gribbin in this riveting book. He focuses on what we know—or think we know—about ten controversial, unanswered issues in the physical sciences and explains how current cutting-edge research may yield solutions in the very near future. With his trademark facility for engaging readers with or without a scientific background, the author explores ideas concerning the creation of the universe, the possibility of other forms of life, and the fate of the expanding cosmos. He examines “theories of everything,” including grand unified theories and string theory, and he discusses the Big Bang theory, the origin of structure and patterns of matter in the galaxies, and dark mass and dark ene...

  10. Clinical experience with TENS and TENS combined with nitrous oxide-oxygen. Report of 371 patients.

    OpenAIRE

    Quarnstrom, F. C.; Milgrom, P.

    1989-01-01

    Transcutaneous electrical nerve stimulation (TENS) alone or TENS combined with nitrous oxide-oxygen (N2O) was administered for restorative dentistry without local anesthesia to 371 adult patients. A total of 55% of TENS alone and 84% of TENS/N2O visits were rated successful. A total of 53% of TENS alone and 82% of TENS/N2O patients reported slight or no pain. In multivariable analyses, pain reports were related to the anesthesia technique and patient fear and unrelated to sex, race, age, toot...

  11. The next ten years in neonatology: new directions in research

    Directory of Open Access Journals (Sweden)

    Vassilios Fanos

    2014-06-01

    Full Text Available This paper is a prelude to proceedings of the 10th International Workshop on Neonatology to be held in Cagliari, Italy from October 21st to 25th, 2014. These proceedings will be a significant milestone, highlighting the new frontiers of perinatal and neonatal research. Over the five days of this meeting, we aim to (1 examine the roots of the new directions in perinatal and neonatal research; (2 predict the trajectories of advancement in medical technologies, research, clinical care and teaching that will be the future of perinatology and neonatology. The discussion will be in four sections:back to the future: the placenta and perinatal programming;paradigm shift: the revolution of metabolomics in perinatalogy and neonatology;brave new world: the microbiome and microbiomics from perinatal to adult life;new inhabitants on the planet earth: adults who were born with extremely low birth weight. Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiou

  12. Ten Years of Support for Basic Scientific Research by CONACYT

    Directory of Open Access Journals (Sweden)

    Luis Humberto Fabila Castillo

    2014-01-01

    Full Text Available This paper reviews the results of ten years of support for basic scientific research by the CONACYT. The paper identifies the strongest areas of knowledge in basic science in Mexico and concludes that the institutions where basic science is done are mainly public higher education institutions, followed by also public research centers, while private institutions of higher education and companies carry out almost no research in basic science. Findings show that research on basic science in state universities has grown impressively in recent years, reaching the level of the institutions of higher education of the Federal District. Finally, the implications of these findings as well as the public policies through which support has been granted are discussed.

  13. Eight to ten years follow-up after carotid endarterectomy

    DEFF Research Database (Denmark)

    Knudsen Rathenborg, Lisbet; Sillesen, H; Schroeder, T

    1990-01-01

    Follow-up information was obtained on 185 patients who consecutively underwent carotid endarterectomy eight to ten years previously. Doppler ultrasound examination was performed in 59 patients who were still alive and living within 100 miles of the hospital. Using lifetable analysis, the annual...... of restenosis and the development of symptoms, perhaps with the exception of internal carotid artery occlusion, which is not an accepted indication for carotid endarterectomy. Together with recent data from the literature, these observations challenge the indication for reoperative carotid surgery....... rate of focal strokes was estimated to be 2% and 1.5% on the operated and the contralateral, non-operated carotid artery, respectively. Doppler examination revealed 48% re-stenoses, including 14% occlusion and 15% greater than 50% stenosis. However, there was no association between the occurrence...

  14. Foothills Model Forest: a ten-year review

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, R.

    2002-04-01

    The first ten years of the Foothills Model Forest, established in 1992, is reviewed. The model forest has been established to develop sustainable forest management within the broader concept of sustainable development and integrated resource management. The project focuses on issues such as wildlife habits and habitats; biodiversity monitoring; natural disturbance trends and patterns; and socio-economic studies. In Phase One of the Canadian Model Forest Network the Foothills Model Forest focused primarily on conducting world class research to advance the concept of sustainable forest management. Phase Two was devoted to communicating the results of that research, with a strong emphasis on generating baseline awareness of the concept of sustainable forest management and creating public awareness of the project's mandate in Alberta. Work during the next five years is expected to focus on demonstration and implementation of research results to forest managers and practitioners and others with a stake in the continued sustainability of Alberta's forests. The Sustainable Forest Management project shares a common objective with the Alberta Chamber of Resources' Integrated Landscape Management project; both projects recognise that reducing the industrial footprint is key to sustainable development. The emphasis on demonstration and implementation in the third phase of the Foothills Model Forest is expected to ensure continued sustainability of forests, ecosystems, communities and resources, with full recognition of the fact that the goal of sustainable development can be achieved only by full cooperation and integrated action of all stakeholders.

  15. Ten years of integrated care for the older in France

    Directory of Open Access Journals (Sweden)

    Dominique Somme

    2011-12-01

    Full Text Available Background: This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population.Policies: Over the last ten years, the French health care system has been principally influenced by two competing linkage models that failed to integrate social and health care services: local information and coordination centers, governed by the social field, and the gerontological health networks governed by the health field. In response to this fragmentation, Homes for the Integration and Autonomy for Alzheimer patients (MAIAs is currently being implemented at experimental sites in the French national Alzheimer plan, using an evidence-based model of integrated care. In addition, the state's reforms recently created regional health agencies (ARSs by merging seven strategic institutions to manage the overall delivery of care.Conclusion: The French health care system is moving from a linkage-based model to a more integrated care system. We draw some early lessons from these changes, including the importance of national leadership and governance and a change management strategy that uses both top-down and bottom-up approaches to implement these reforms.

  16. Ten years of integrated care for the older in France

    Directory of Open Access Journals (Sweden)

    Dominique Somme

    2011-12-01

    Full Text Available Background: This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Policies: Over the last ten years, the French health care system has been principally influenced by two competing linkage models that failed to integrate social and health care services: local information and coordination centers, governed by the social field, and the gerontological health networks governed by the health field. In response to this fragmentation, Homes for the Integration and Autonomy for Alzheimer patients (MAIAs is currently being implemented at experimental sites in the French national Alzheimer plan, using an evidence-based model of integrated care. In addition, the state's reforms recently created regional health agencies (ARSs by merging seven strategic institutions to manage the overall delivery of care. Conclusion: The French health care system is moving from a linkage-based model to a more integrated care system. We draw some early lessons from these changes, including the importance of national leadership and governance and a change management strategy that uses both top-down and bottom-up approaches to implement these reforms.

  17. [TEN YEARS OF OPIOID CONSUMPTION BY CHILDREN (2001-2010)].

    Science.gov (United States)

    Freud, Tamar; Sherf, Michael; Battat, Erez; Vardy, Daniel; Shvartzman, Pesach

    2015-09-01

    Opioids are considered a cornerstone in the treatment of pain. They are rarely used in almost half of the countries of the world, especially in children. The aim of this study was to assess opioid use over a ten-year study period from 2001-2010, among children 0-18 years old who are members of Clalit Health Services (CHS), the largest HMO in Israel Data on the purchase of opioids, authorized for use in Israel, was obtained from the computerized databases of CHS. In addition, the patient's demographic details and cancer morbidity were also extracted. The data was analyzed after all the doses of all opioids consumed (fentanyl patch, oxycodone, methadone, hydromorphone, oral transmucosal fentanyl) were converted into oral morphine equivalents (OME). In all, 1,098 children purchased at least one opioid prescription during the study period. Of them, 27.3% had a diagnosis of cancer and 55.5% were female. A 42% decrease in total annual OME (mg) purchased, from 209,443 mg to 122,048 mg, was observed from 2001 to 2010. There was no specific pattern or trend in the annual number of pediatric and adolescent patients who purchased at least one opioid drug during the study period. In 86.5% of the cases, children with a non-cancer cause of pain purchased opioids for only one month. There is a low and inconsistent rate of opioid consumption among pediatric and adolescent members of the CHS. Further study is needed to explore the reasons for this low opioid consumption rate in this population group.

  18. Programa de oxigenoterapia domiciliar para crianças egressas de uma unidade neonatal: relato da experiência de dez anos Home oxygen therapy program for infants after neonatal unit discharge: report of a ten-year experience

    Directory of Open Access Journals (Sweden)

    Elaine Aparecida L. Garcia

    2010-09-01

    Full Text Available OBJETIVO: Descrever os resultados do programa de oxigenoterapia domiciliar, com uso de concentrador de oxigênio, utilizado por crianças egressas de uma unidade neonatal ao longo de seus primeiros dez anos. MÉTODOS: Estudo de corte transversal com componente analítico para avaliar o programa de oxigenoterapia domiciliar de uma unidade neonatal de um hospital público universitário do interior do Estado de São Paulo durante o período de novembro de 1996 a dezembro de 2006. RESULTADOS: Foram identificadas 160 crianças com indicação de oxigenoterapia domiciliar, das quais 63,3% apresentavam displasia broncopulmonar. Em média, 3,0% de todos os pacientes internados e 8,6% dos recém-nascidos com peso inferior a 1500g ao nascer receberam alta em oxigenoterapia. A duração média do uso de O2 no domicílio foi de 42,3±54,0 dias. Na comparação das características demográficas da população e do tempo de uso de O2 domiciliar, não se observaram diferenças significativas entre os anos. Não houve correlação entre o tempo de ventilação mecânica e a duração da terapia domiciliar. Houve necessidade de cuidados especiais, além do uso de O2 e medicações, em 22,3% dos casos. Nos primeiros dois anos de vida, a taxa de morbidade e de mortalidade foram, respectivamente, 40,1 e 14,1%. CONCLUSÕES: O uso de oxigênio domiciliar, com sistema de concentrador de oxigênio, é uma alternativa terapêutica factível em nosso meio, merecendo mais atenção dos profissionais de saúde e maior investimento das instituições de saúde. São necessários mais estudos nacionais para se aprimorar a qualidade do atendimento e a segurança destes programas para a população neonatal.OBJECTIVE: To describe the results of a home oxygen therapy program consisting of the use oxygen concentrator by children discharged from a neonatal unit during their first 10 years of the program. METHODS: Cross-sectional analytical study with data collection from

  19. Pierre Bourdieu, dez anos depois Pierre Bourdieu, ten years after

    Directory of Open Access Journals (Sweden)

    Cristina Carta Cardoso de Medeiros

    2013-03-01

    Full Text Available O presente texto procura discutir o legado deixado pelo sociólogo francês Pierre Bourdieu. Dez anos após sua morte, tem-se discutido, em nível internacional, a relevância deste autor, um dos mais influentes e citados teóricos do mundo. Para a identificação desta influência no Brasil, mais especificamente no campo educacional brasileiro, pesquisou-se nas teses e dissertações encontradas no banco de dados da CAPES, que referenciavam Bourdieu, de que forma estaria se dando a apropriação de seu quadro teórico de análise para construção de conhecimento no referido campo. Concluiu-se que o número de produções defendidas nos Programas de Pós-Graduação em Educação no Brasil, de 1965 a 2010, cresce de forma exponencial, demonstrando o quão profícua a utilização da teoria sociológica de Bourdieu tem se mostrado para explicar a realidade da Educação no Brasil na contemporaneidade. Encerra-se o artigo com uma reflexão sobre a consideração do status de Bourdieu como um clássico da Sociologia que, paradoxalmente, se mostra mais atual e vivo do que qualquer outro autor quando se trata de aplicar seu princípio maior, a saber, analisar o mundo social e suas lógicas, desvelando as formas de dominação e as misérias sociais.This paper's intent is to discuss the legacy left by the French sociologist Pierre Bourdieu. Ten years after his death, it has been discussed at an international level the relevance of this author, one of the most cited and influential theorists in the world. To identify such influence in Brazil, more specifically in the Brazilian educational field, we investigated theses and dissertations found in CAPES database, which referenced Bourdieu, to identify how those works use his theoretical framework of analysis for construction of knowledge in that field. It was concluded that the number of productions held in post-graduate programs in education in Brazil, from 1965 to 2010, grows exponentially

  20. Ten Years after College: Comparing the Employment Experiences of 1992-93 Bachelor's Degree Recipients with Academic and Career-Oriented Majors. Postsecondary Education Descriptive Analysis Report. NCES 2008-155

    Science.gov (United States)

    Choy, Susan P.; Bradburn, Ellen M.

    2008-01-01

    This report examines college graduates' work experiences in the first 10 years after they graduated. It describes their labor force status, employment stability and intensity, occupations and industries, salaries and benefits, and perceptions about their jobs. The report focuses on differences across undergraduate majors, comparing the…

  1. Ten years of multidisciplinary mental health guidelines in the Netherlands.

    Science.gov (United States)

    Franx, Gerdien; Niesink, Peter; Swinkels, Jan; Burgers, Jako; Wensing, Michel; Grol, Richard

    2011-08-01

    From 1999 until 2009 the National Steering Group for Multidisciplinary Guideline Development in Mental Health led a national guideline programme in the Netherlands. Ten service user and carer groups and 30 professional organizations were involved. Within the programme 13 practice guidelines and a range of other deliverables, such as patient versions, checklists and implementation materials, were produced. Lessons learned included the methodology of developing guidelines, service user and carer involvement, and the dissemination and implementation of the guidelines. There are important future challenges such as following a strict and transparent methodology, adhering to process management, improving integration of the service user and professional perspectives, and bridging the gap between guideline and practice.

  2. The Last Ten Years in the Bristish Education System

    OpenAIRE

    Rodriguez Rico, Juan Antonio

    2016-01-01

    Después de la Segunda Guerra mundial, Gran Bretaña se encontró con una escasez de trabajadores cualificados sin precedente. El problema más importante era como animar a la población más joven a continuar su educación ya que cada uno de ellos era una pieza imprescindible en la reconstrucción nacional y en la imagen internacional del país. La discriminación racial y la filosofía de Charles Darwin ayudó a elaborar la idea que el británico blanco tenía la superioridad económica , moral e inte...

  3. Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival

    Science.gov (United States)

    ... Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival For some women with breast cancer , taking adjuvant ... Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival was originally published by the National Cancer Institute.” ...

  4. TESTICULAR TUMORS IN PORT HARCOURT (A ten-year review)

    African Journals Online (AJOL)

    testicular tumors.12 '. RESULTS. A'total of twelve testicular tumours were reviewed. The yOungest patient was 3 years old while the oldest was. 48 years old. I. Table 1 ... 66.7% preschool age group and drivers had 16.7% each. Table I : Age distribution of; patients with testicular tumours. Age group Number Percent in years.

  5. Ten-year retrospective: OPEC and the world oil market

    Energy Technology Data Exchange (ETDEWEB)

    Gately, D.

    1984-09-01

    This paper reviews the main events in the world oil market since 1973 and some major explanations as to what happened and why (Section I). Then there is a discussion of some projections for the next two decades and of some implications of various theories about OPEC's decisionmaking process (Section II). Section III summarizes what we have learned about modeling OPEC and the world oil market. This includes: the dominant theoretical approach based on the wealth-maximization model of Harold Hotelling (1931); the simulation approach most common in the applied literature, which envisages target-capacity-utilization pricing by OPEC; and the difficult problem of modeling price behavior during disruptions. Finally, Section IV discusses some important unresolved issues, both theoretical and empirical. A variety of contributions to the literature are considered, but the discussion pays special attention to two important recent works. One is the book OPEC Behavior and World Oil Prices (1982) (EAPA 9:3899) edited by James Griffin and David Teece, an important collection of papers on OPEC and world oil, prepared for a 1981 conference at the University of Houston. The other is the 1980 to 1981 world oil study by the Energy Modeling Forum of Stanford Univesity, which involved ten prominent models of the world oil market. 31 references.

  6. Ten-year growth of planted slash pine after thinnings

    Science.gov (United States)

    Hans G. Enghardt; W.F. Mann

    1972-01-01

    volume growth of slash pine between ages 17 and 27 years was directly related to residual basal area per acre after thinning. Diameter growth was inversely related to stand density, and very heavy cutting was required to attain a rate of 3 inches in 10 years.

  7. The future of the Dutch public library: ten years on

    NARCIS (Netherlands)

    Frank Huysmans; Carlien Hillebrink

    2008-01-01

    The public library is the biggest cultural institution in the Netherlands, with around 4 million members and 130 million items lent each year. Inspite of this, the library is under pressure: membership numbers and borrowings have been declining steadily for several years. In the last six

  8. Five to ten MA experiments using flat plate explosive generators

    Energy Technology Data Exchange (ETDEWEB)

    Caird, R. S.; Fowler, C. M.; King, J. C. (James Carrel); Oona, H. (Henn); Tasker, D. G. (Douglas G.); Goforth, J. H. (James H.)

    2001-01-01

    High explosive pulsed power (HEPP) techniques can address a wide range of pulsed power needs. The basis for HEPP techniques is the use of high explosives to reduce the inductance of a current-carrying circuit, thus multiplying the current due to magnetic flux conservation. For the past twenty years at Los Alamos, our high energy density physics (HEDP) program has followed a path leading to more sophisticated and higher current (and often power) systems. Twenty years ago, we had the capability of conducting tests at 10, or even 30 MA, with no power conditioning and low inductance loads. The time scale of the experiment was the time it took to compress the flux explosively, and our fastest generator with high current capability was a plate generator. The operating time of the generator is less than 15 {micro}s, and flux loading requires either an additional {approx}60 {micro}s or a reduced-efficiency inductive coupling scheme. We could also deliver shortened pulses to select loads by completing our generator circuit, initially, with a relatively high inductance circuit element, then switching in a lower inductance with 2-3 {micro}s left of the generator pulse. Figure 1 shows the results of such a test. The test was conducted in 1974 to investigate our capability to drive plasma z-pinch experiments for the production of soft x-rays, and was a pulsed power success. However, our understanding of vacuum power flow issues was not mature enough at that time to design a functioning plasma z-pinch load. There was a renewed need for such a system in 1980, and at that time we began assembling a complete set of techniques required for success. We first fielded a baseline test using a simplified version of the HEPP system that generated the Figure 1 data. Subsequent tests followed a 'bite size' philosophy. That is, we first designed a complete system for a level of complexity at which we believed success could be achieved. We conducted tests of that system, and once it

  9. Odontogenic Mixoma in a Ten-Year-Old Patient.

    Science.gov (United States)

    Triana, Ennya Lieseth Leonel; Melo-Uribe, Mario; Castro-Núñez, Jaime

    2016-10-01

    Odontogenic myxomas are benign, rarely seen intraosseous tumors arising from the embryonic connective tissue associated to tooth formation. The authors present the case of a 10-year-old patient affected by this entity.

  10. Ten-year survival of patients with oesophageal squamous cell ...

    African Journals Online (AJOL)

    oesophageal junction ... after treatment of cancer. Reports of actual 10-year survivors of oesophageal squamous cell carcinoma (SCC) are rare, and demographic .... nodes, number of resected lymph nodes, adjuvant treatment and length of survival.

  11. Prevalence of loneliness over ten years among the oldest old.

    Science.gov (United States)

    Nyqvist, Fredrica; Cattan, Mima; Conradsson, Mia; Näsman, Marina; Gustafsson, Yngve

    2017-06-01

    This study examined the prevalence of loneliness among the oldest old within a 10-year period and studied the influence of various sociodemographic, social and health characteristics on loneliness. The study used population-based data from the Umeå85+/GErontological Regional DAtabase-study (GERDA) for the years 2000-2002, 2005-2007 and 2010-2012 including 85-year-old, 90-year-old and ⩾95-year-old participants. A final sample of 304 participants in 2000-2002, 329 participants in 2005-2007 and 401 participants in 2010-2012 was included in the analyses. Although the level of loneliness was already high in 2000-2002 (49.3% reported frequent loneliness), the results showed limited changes in loneliness during the 10-year study period. Loneliness was closely related to living alone, depressive symptoms and living in institutional settings. Although societal changes such as solitary living and growing urbanization suggest a changing trend in loneliness, we found that the prevalence of loneliness was relatively stable in this study. Nevertheless, loneliness is common among the oldest old and a focus on social issues related to living arrangements and on depressive symptoms is important in understanding loneliness.

  12. Ten year neurocognitive trajectories in first-episode psychosis

    DEFF Research Database (Denmark)

    Simonsen, Erik; Barder, Helene E.; Sundet, Kjetil

    2013-01-01

    Memory for patients with psychotic relapse in the first year[F-(4,F- (38)) = 5.8, p = 0.001, eta(2) = 0.40]. Conclusions: Main findings are long-term stability in neurocognitive functioning in FEP patients, with the exception of verbal memory in patients with psychotic relapse or non-remission early......Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant subgroups even more so. We report 10 year...... longitudinal neurocognitive development in a sample of FEP patients, and explore whether the trajectories of cognitive course are related to presence of relapse to psychosis, especially within the first year, with a focus on the course of verbal memory. Method: Forty-three FEP subjects (51% male, 28 +/- 9...

  13. Beijing--ten years after Mao: country profile.

    Science.gov (United States)

    Rusoff, D

    1987-03-01

    An examination of demographic trends in Beijing--China's capital and the center of its political and cultural life--can yield important information on future consumer trends for the country as a whole. Age and income are the most influential demographic characteristics in determining what people will buy. As a result of economic reforms under Deng Xiaoping, per capita income available for living expenses in urban China almost doubled between 1978 and 1984, from 316 to 608 yuan. By the year 2000, the purchase of commodities in urban staff and worker households is projected to account for 88% of total expenditures, with noncommodity expenditures accounting for the remaining 12%. The average age of 1st marriage and 1st childbirth is gradually rising, while the interval between marriage and 1st birth is decreasing. The fertility rate in Beijing was 1.6 births/woman in 1981 and 91% of all births in 1983 were 1st births. Despite its one-child policy and drastically reduced fertility rates, Beijing's population will continue to grow until the large numbers of young people born during the high fertility period of the 1950s and 1960s pass out of their childbearing years. Given a life expectancy of 78 years for men and 80 years for women and an average of 1.5 births/woman, the proportion of those over age 65 years in China is projected to stand at 29% by 2040. This trend toward demographic aging suggests a need to revamp social policies to alleviate the stress placed on Chinese families and increase financial aid to the elderly. There have been proposals to adopt a norm that would allow couples 2 children spaced 8-10 years apart. The average household size in Beijing in 1982 was 3.9 persons, with 2.3 jobholders/household. Between 1981 and 1984, the percentage of urban households having annual per capita incomes above 600 yuan rose from 18% to 49%.

  14. Chandra: Ten Years of Amazing Science with a Great Observatory

    Science.gov (United States)

    Weisskopf, Martin C.

    2009-01-01

    We review briefly review the history of the development of the Chandra X-Ray Observatory, highlighting certain details that many attendees of this Conference might not be aware of. We then present a selection of scientific highlights of the first 10 years of this remarkable and unique mission.

  15. NHS litigation in bariatric surgery over a ten year period.

    Science.gov (United States)

    Ratnasingham, Kumaran; Knight, James; Liu, Mamie; Karatsai, Eleni; Humadi, Samer; Irukulla, Shashi

    2017-04-01

    Negligence claims in the UK NHS has increased over the last 30 years. The aim of this present study was determine the number of claims and the cost of litigation in Bariatric Surgery and compare it to similar other specialties. Data was received from NHS Litigation Authority (NHSLA) in response to Freedom of Information data request. There was a total of 7 claims, of which 4 were successful. The total pay out sum was £210,000 in 10 years. This is a very low amount compared to other surgical specialties. This low level of litigation probably indicates that the current bariatric surgical services in the NHS are delivering safe care with good patient satisfaction. This needs to be carefully considered prior to changing the payment tariffs for bariatric surgery. Copyright © 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  16. 1959 - 1969 Ten years in the life of a machine

    CERN Multimedia

    1969-01-01

    Operation and development of the PS have brought a dramatic improvement in its capabilities. This article describes the years of getting to know the machine and of developing its potential, picking out some major landmarks on the way. The article was put together with the help of P.H. Standley (PS Division Head), C.S. Taylor (Linac), G. Plass, W. Richter (Mam Ring), M. Georgijevic (Power Supply), J.H.B. Madsen (Operation), and G.L. Munday (Experimental Areas).

  17. Inflammatory dentigerous cyst in a ten-year-old child

    OpenAIRE

    Kumar, Rakesh; Singh, Rajeev K.; Pandey, Ramesh K.; Mohammad, Shadab; Ram, Hari

    2012-01-01

    Dentigerous cyst may be developmental or inflammatory in origin. The latter is found only in mixed dentition with a low frequency. Treatment of inflammatory type of dentigerous cyst in children should be done with the aim of saving developing permanent teeth which should not be sacrificed as far as possible. This is a case report of a large inflammatory dentigerous cyst in a 10-year-old female patient treated conservatively by marsupialization method saving all teeth (mandibular permanent lef...

  18. The Gestational Trophoblastic Diseases: A Ten Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Razieh Mohammadjafari

    2010-01-01

    Full Text Available Background: Gestational trophoblastic disease (GTD defines a heterogenenous group ofinterrelated lesions that arise from the trophoblastic epithelium of the placenta. There are severalhistologically distinct types of GTD: hydatiform mole (complete or partial, persistant/invasivegestational trophoblastic neoplasia (GTN, choriocarcinoma and placenta site trophoblastictumors. The aim of this study was to determine the frequency and risk factors of GTD amongwomen admitted to Imam Khomeini Hospital in Ahvaz, Iran.Materials and Methods: This was a cross-sectional study conducted at Imam KhomeiniHospital in Ahvaz, Iran. All hospital records related to GTD (132 from 1996 until 2006 werereviewed. Demographic and histo-pathologic characteristics were extracted. Chi-square andFisher-exact tests were used to analyze all variables. P ≤ 0.05 was considered statisticallysignificant. SPSS, version 11 was used for statistical analysis.Results: The mean age of patients was 27.6 years. Most patients who presented with GTDwere of ages 18-35 years (71.3%. There was no relationship between age and hydatiformmole during the reproductive years. There were 28 (18.9% patients over the age 40, of which18 (15.90% of these had a complete hydatiform mole. Within this group, 9 (6.8% changedto a persistent mole. There was a significant relationship between age over 40 and completemole (p<0.02. The percentage of patients with blood groups A and O was the same (37.9%.There was a significant relationship between blood groups (O+ and A+ and complete mole(p<0.05.Conclusion: The most common age range for hydatiform mole was 18-35 years. Women overthe age of 40 had a more complete hydatiform mole, which is similar to the other countries.Age and blood group are two risk factors for hydatiform mole.

  19. Poland in the European Union.Ten Years of Membership

    OpenAIRE

    Katarzyna Kolodziejczyk

    2016-01-01

    Twelve years have passed since the Polish entry into the European Union. For Poland the date of 1 May 2004 is the culmination of a transformation process launched at the end of the Cold War in 1989. One of the priorities of Polish foreign policy, the expansion of the political, economic and cultural relations with Western Europe and the United States has been met. This approach has been described as ‘the return to Europe’. Membership in the European Union changed the Polish economy and the ne...

  20. Ten-year survival rate for cantilevered fixed partial dentures.

    Science.gov (United States)

    Anderson, James D

    2005-01-01

    PubMed (1966-April 2004) provided the primary data source along with the bibliographies from identified articles and reviews. A manual search of two relevant journals (Clinical Implant Dentistry and Related Research, Clinical Oral Implants Research, International Journal of Oral & Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, International Journal of Prosthodontics, Journal of Clinical Periodontology, Journal of Periodontology and Journal of Prosthetic Dentistry published; published 2001-2003) provided a further source of data. Because there were no randomised controlled trials (RCT) that compared fixed partial dentures (FPD) with and without cantilever extensions, other studies were selected if they met the following criteria: were published in the English language; were prospective and retrospective cohort studies; had a mean follow-up of >5 years; included patients who were clinically examined at follow-up; and reported details on suprastructures and described at least one-third of reconstructions as FPD. Two independent reviewers screened articles for inclusion. Disagreements were resolved by discussion and agreement determined by kappa. Two reviewers extracted data on the survival and success of the reconstructions and on biological and technical complications. Failure and complication rates were calculated by dividing the number of events by the total exposure time. Three prospective and 10 retrospective cohort studies incorporating 700 patients and 816 FPD were included. The mean number of cantilever extensions ranged from 1.1 to 6.0. Meta-analyses gave an estimated survival, after 10 years, of 81.8% [95% confidence interval (CI), 78.2-84.9] and a proportion success of 63% (95% CI, 54.7-70.2). Considering biological complications using Poisson model analyses, the estimated rate of FPD lost because of caries after 10 years was 3.1% (95%CI, 1.0-8.8) and that for loss of vitality was 32.6% (95% CI, 13.9-64.9). The rate

  1. Inflammatory dentigerous cyst in a ten-year-old child.

    Science.gov (United States)

    Kumar, Rakesh; Singh, Rajeev K; Pandey, Ramesh K; Mohammad, Shadab; Ram, Hari

    2012-01-01

    Dentigerous cyst may be developmental or inflammatory in origin. The latter is found only in mixed dentition with a low frequency. Treatment of inflammatory type of dentigerous cyst in children should be done with the aim of saving developing permanent teeth which should not be sacrificed as far as possible. This is a case report of a large inflammatory dentigerous cyst in a 10-year-old female patient treated conservatively by marsupialization method saving all teeth (mandibular permanent left canine, first and second premolars) in relation to the cyst.

  2. Methadone-related deaths. A ten year overview.

    Science.gov (United States)

    Vignali, Claudia; Stramesi, Cristiana; Morini, Luca; Pozzi, Fulvia; Groppi, Angelo

    2015-12-01

    Over the last 10 years we have registered in our district (about 500,000 inhabitants) 36 cases of fatal methadone poisoning, involving both patients on treatment and naive subjects: this is a significant increase of deaths due to methadone use, misuse or abuse compared with previous years. Twenty-four patients (66.7%) were on methadone maintenance programs for heroin detoxification, while 12 (33.3%) were taking the drug without a medical prescription. The average blood concentration of methadone in patients undergoing a maintenance program was 1.06 mg/L (0.21-3.37 mg/L), against 0.79 mg/L (0.2-3.15 mg/L) in those taking the non-prescribed drug. Since 111 heroin-related deaths were recorded in our district in the same period, the fact that there appear to be many methadone deaths (about a third of heroin-related deaths) cannot be overlooked. The aim of this work is to understand the possible reasons for such a large number of methadone-related deaths. On this subject, we have noticed that risks associated with methadone intake are often underestimated by clinicians prescribing the drug: sometimes methadone is prescribed without taking into account patient's tolerance to opiates, and a large number of subjects enrolled in methadone maintenance programs in Italy, have also been given take-home doses, thus increasing the risk of abuse and diversion. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. Otological Findings Ten Years after Myringotomy with Tympanostomy Tube Insertion

    Directory of Open Access Journals (Sweden)

    Ali Goljanian Tabrizi

    2011-01-01

    Full Text Available Introduction: To study the long-term complications of tympanostomy tube insertion in young children 10 years after surgery.   Materials and Methods: In September 2011, the medical records of all patients who had undergone myringotomy with tympanostomy tube insertion between February 2000 and March 2001 at the two general hospitals of Isfahan University of Medical Sciences were studied. Of the 98 patients who fulfilled the inclusion criteria, 82 patients agreed to participate and were enrolled in the study. The complications of the operation were evaluated in these patients.   Results: Of the 164 ears that were operated on, myringosclerosis was found in 17.1%, atrophy of the tympanic membrane in 1.2%, permanent perforation of the tympanic membrane in 0.6% and tympanic membrane atelectasis in 0.6%. None of the patients developed cholesteatoma as a complication of tympanostomy tube insertion.   Conclusion:  Considering the low risk of serious complications after 10 years, tympanostomy tube insertion is a safe and effective treatment option in the treatment of otitis media with effusion.

  4. Ten-year publication trends in dermatology in mainland China.

    Science.gov (United States)

    Xin, Shujun; Mauro, Jacqueline A; Mauro, Theodora M; Elias, Peter M; Man, Mao-Qiang

    2014-10-01

    China has been experiencing huge changes in all aspects, including dermatologic research, since its reform in 1978. However, it is not known how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines. In the present study, we analyzed publication trends from dermatology departments in mainland China from 2002 to 2011. All publication data were obtained from www.pubmed.com. Only papers published from dermatology departments in mainland China were used for analysis. The number of publications increased 10-fold over this 10-year period. A total of 1231 articles were published in English in 251 journals between 2002 and 2011. A total of 129 journals published only one paper from dermatology departments in mainland China. Over 60% of articles were original research, and 21.7% were case reports. Among these 251 journals, foremost was the Journal of Clinical Experimental Dermatology, which published 5.9% of all papers from mainland China; 2.7% of papers were published in the Journal of Investigative Dermatology. The number of publications positively correlated with the changes in gross domestic product per capita during the study period. These results suggest that the number of publications in the dermatology field has increased markedly in mainland China over the last 10 years. This dramatic increase in publications could be attributed, at least partially, to the significant improvement in economic conditions in mainland China. © 2013 The International Society of Dermatology.

  5. Ten-Year Course of Borderline Personality Disorder

    Science.gov (United States)

    Gunderson, John G.; Stout, Robert L.; McGlashan, Thomas H.; Shea, M. Tracie; Morey, Leslie C.; Grilo, Carlos M.; Zanarini, Mary C.; Yen, Shirley; Markowitz, John C.; Sanislow, Charles; Ansell, Emily; Pinto, Anthony; Skodol, Andrew E.

    2011-01-01

    Context Borderline personality disorder (BPD) is traditionally considered chronic and intractable. Objective To compare the course of BPD’s psychopathology and social function with that of other personality disorders and with major depressive disorder (MDD) over 10 years. Design A collaborative study of treatment-seeking, 18-to 45-year-old patients followed up with standardized, reliable, and repeated measures of diagnostic remission and relapse and of both global social functioning and subtypes of social functioning. Setting Nineteen clinical settings (hospital and outpatient) in 4 northeastern US cities. Participants Three study groups, including 175 patients with BPD, 312 with cluster C personality disorders, and 95 with MDD but no personality disorder. Main Outcome Measures The Diagnostic Interview for DSM-IV Personality Disorders and its follow-along version (the Diagnostic Interview for DSM-IV Personality Disorders–Follow-Along Version) were used to diagnose personality disorders and assess changes in them. The Structured Clinical Interview for DSM-IV Axis I Disorders and the Longitudinal Interval Follow-up Evaluation were used to diagnose MDD and assess changes in MDD and in social function. Results Eighty-five percent of patients with BPD remitted. Remission of BPD was slower than for MDD (Ppersonality disorders (Ppersonality disorders (P=.008). All BPD criteria declined at similar rates. Social function scores showed severe impairment with only modest albeit statistically significant improvement; patients with BPD remained persistently more dysfunctional than the other 2 groups (Pdisorder. PMID:21464343

  6. Ten Years Back, Five Years Forward: The Data Seal of Approval

    OpenAIRE

    Ingrid Dillo; Lisa de Leeuw

    2015-01-01

    If we want to share data, the long-term storage of those data in a trustworthy digital archive is an essential condition. Trust is the basis of storing and sharing data. That trust must be present in the various stakeholders involved. Certification of digital archives can make an important contribution to the confidence of these stakeholders in the digital archives.Ten years ago DANS was assigned the task of developing a Seal of Approval for digital data to ensure that archived data can still...

  7. Poland in the European Union.Ten Years of Membership

    Directory of Open Access Journals (Sweden)

    Katarzyna Kolodziejczyk

    2016-01-01

    Full Text Available Twelve years have passed since the Polish entry into the European Union. For Poland the date of 1 May 2004 is the culmination of a transformation process launched at the end of the Cold War in 1989. One of the priorities of Polish foreign policy, the expansion of the political, economic and cultural relations with Western Europe and the United States has been met. This approach has been described as ‘the return to Europe’. Membership in the European Union changed the Polish economy and the new politics opened up new opportunities for businesses and citizens. The aim of the article is to analyze the balance of the Polish membership in the European Union in the economic, financial, political and social dimensions.

  8. Minimal intervention dentistry procedures: a ten year retrospective study.

    Science.gov (United States)

    Freitas, Mfl; Santos, Jm; Fuks, A; Bezerra, Acb; Azevedo, Tdpl

    2014-01-01

    Minimal Intervention Dentistry (MID) is an effective treatment approach with increasing acceptance among dental professionals. This study aimed to evaluate the MID impact on Dentistry by analyzing procedures performed on patients treated at a Pediatric Dentistry Graduate Program clinic which implemented MID. The number of procedures including sealants, modified atraumatic restorative treatment (mART), resin crowns, direct pulp capping, pulpotomy, pulpectomy, and deciduous/ permanent extractions from 333 pediatric patients treated between the years 2001 to 2003 and 2008 to 2010 in Distrito Federal, Brazil were analyzed. Statistical analysis involved chi-square and G Williams tests. 783 procedures were analyzed and demonstrated that there was a significant reduction of sealant placement in the last triennium when compared to the first one (ppulpectomy (p=0.0002). Based on the results, MID represented a positive impact on the intervention on caries lesions in patients, mainly reflected by the significant reduction in the number of direct pulp capping, pulpotomy and pulpectomy.

  9. Purpose in life predicts allostatic load ten years later.

    Science.gov (United States)

    Zilioli, Samuele; Slatcher, Richard B; Ong, Anthony D; Gruenewald, Tara L

    2015-11-01

    Living a purposeful life is associated with better mental and physical health, including longevity. Accumulating evidence shows that these associations might be explained by the association between life purpose and regulation of physiological systems involved in the stress response. The aim of this study was to investigate the prospective associations between life purpose and allostatic load over a 10-year period. Analyses were conducted using data from the Midlife in the United States (MIDUS) survey. Assessment of life purpose, psychological covariates and demographics were obtained at baseline, while biomarkers of allostatic load were assessed at the 10-year follow-up. We found that greater life purpose predicted lower levels of allostatic load at follow-up, even when controlling for other aspects of psychological well-being potentially associated with allostatic load. Further, life purpose was also a strong predictor of individual differences in self-health locus of control-i.e., beliefs about how much influence individuals can exert on their own health-which, in turn, partially mediated the association between purpose and allostatic load. Although life purpose was also negatively linked to other-health locus of control-i.e., the extent to which individuals believe their health is controlled by others/chance-this association did not mediate the impact of life purpose on allostatic load. The current study provides the first empirical evidence for the long-term physiological correlates of life purpose and supports the hypothesis that self-health locus of control acts as one proximal psychological mechanism through which life purpose may be linked to positive biological outcomes. Copyright © 2015. Published by Elsevier Inc.

  10. The Catholic School under Scrutiny: Ten Years of Research in Italy (1998-2008)

    Science.gov (United States)

    Malizia, Guglielmo; Cicatelli, Sergio

    2011-01-01

    This book delineates the evolution of the Study Centre for Catholic Schools (CSSC) in its first ten years of existence since its foundation in 1998 by the Italian Bishops' Conference. The volume is divided into three main sections. The first outlines the context and the activity of the CSSC during ten years: the role, the functions, the tasks and…

  11. [After ten years of AIDS, a vision emanating from feminism].

    Science.gov (United States)

    Liguori, A L

    1991-01-01

    AIDS and the economic crisis in Mexico are threatening the epidemiologic transition in which infectious diseases ceased to be the only major cause of death and chronic degenerative diseases began to account for a growing proportion of deaths. Many factors combined to produce the sexual, gay, and women's liberation movements beginning in the 1970s. At the beginning of the feminist movement, women proposed different kinds of interpersonal relations both between women and with men. Women together realized their rights to control their own bodies, to sexual enjoyment, to abortion, and to free themselves of feelings of shame and guilt. The weight of moral pressures was lessened and the personal desires of the woman assumed a greater role in selection of sexual partners. Conservative forces grew stronger in the 1980s, and the proliferation of sexually transmitted diseases began to imperil the sexual revolution. But these setbacks were minor compared to AIDS. Now, 10 years after its appearance, it is clear that AIDS is not limited to homosexual men. The number of cases in Mexico increased from none 10 years ago to some 10,000 estimated cases reported and unreported today. 1/6 of the cases are in women. Many women and heterosexuals felt immune from AIDS in the beginning, and some still do, but many more have become aware of the danger. Women now fear contracting AIDS, but they also fear confronting their partners to suggest that they use condoms. Denial may play a role, but deeply rooted cultural factors that women may recognize but fee powerless to change may also be at play. Many women over 30 have difficulty taking the initiative in sexual matters. They are embarrassed to buy condoms and even more embarrassed to propose their use. They imagine that men will consider them "loose" if they carry condoms. Mexican women are poorly prepared to tell their men explicitly what they want sexually, and Mexican men are also poorly equipped to ask what women want, accustomed as they

  12. US-Hungarian Relations Ten Years After 1956

    Directory of Open Access Journals (Sweden)

    Tibor Glant

    2016-10-01

    Full Text Available 1966, the tenth anniversary of the 1956 Revolution, was a key year in US–Hungarian relations. Diplomatic relations were raised from the lowest to the highest level, but suspicion and tension remained. Neither side knew what to expect from the other on account of the anniversary, the Vietnam War, economic and cultural negotiations, and the fate of Cardinal Mindszenty. A traditional diplomatic historical approach is supplemented here with cultural materials to present the full scale of contacts ranging from high political issues to the visit of Hollywood movie star Kirk Douglas in Budapest. First Secretary of the Legation for Press and Cultural Affairs Edward Alexander receives special attention, because he played a crucial role in the events of 1966. As press secretary, he helped calm Hungarian fears over what American journalists might report about the anniversary, while as cultural affairs officer he worked on documenting and expanding American cultural presence in Hungary. In the latter capacity, he opened the USIA Library at the Legation, fraternized with blacklisted painters of the Zuglói Kör [‘Zugló Circle’], monitored the Hungarian stage production of My Fair Lady, and reported on the publication of American literature in Hungarian.

  13. Ten years of integrated care for the older in France.

    Science.gov (United States)

    Somme, Dominique; de Stampa, Matthieu

    2011-01-01

    This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Over the last 10 years, the French health care system has been principally influenced by two competing linkage models that failed to integrate social and health care services: local information and coordination centers, governed by the social field, and the gerontological health networks governed by the health field. In response to this fragmentation, Homes for the Integration and Autonomy for Alzheimer patients (MAIAs) is currently being implemented at experimental sites in the French national Alzheimer plan, using an evidence-based model of integrated care. In addition, the state's reforms recently created regional health agencies (ARSs) by merging seven strategic institutions to manage the overall delivery of care. The French health care system is moving from a linkage-based model to a more integrated care system. We draw some early lessons from these changes, including the importance of national leadership and governance and a change management strategy that uses both top-down and bottom-up approaches to implement these reforms.

  14. Stakeholder perceptions of a school food policy ten years on.

    Science.gov (United States)

    Pettigrew, Simone; Talati, Zenobia; Sauzier, Megan; Ferguson, Amanda

    2018-01-24

    To assess (i) the extent to which stakeholders have accepted and implemented a Healthy Food and Drink Policy for schools a decade after its introduction and (ii) any resulting implications for canteen profitability. Online survey distributed via electronic newsletter to school principals. Western Australian public schools. Principals, teachers, canteen managers, and parents and citizens committee presidents (n 307). Large majorities of respondents reported that the policy has made the foods and drinks provided in schools healthier (85 %) and that the policy constitutes a good opportunity to teach children about healthy eating (90 %). Only small proportions of respondents felt it had been difficult to implement the policy in their schools (13 %) or that the policy fails to accommodate parents' rights to choose the foods consumed by their children (16 %). Most of the policy outcomes assessed in both the initial post-implementation evaluation (2008) and the 10-year follow-up evaluation (2016) demonstrated significant improvement over time. The study results indicate that comprehensive school food policies can favourably influence the foods and drinks provided on school premises and can be highly acceptable to key stakeholders, without adversely affecting profitability. The results are encouraging for policy makers in other jurisdictions considering the implementation of similar policies.

  15. Stevens Johnson syndrome in Pakistan: a ten-year survey.

    Science.gov (United States)

    Ahmed, Y I; Azeem, S; Khan, O; Majid, T H; Ahmed, D; Amin, A; Mahmood, A; Hameed, K

    2004-06-01

    A pre-tested questionnaire-based, retrospective study to highlight the causative factors, mode of presentation, complications and outcome of patients with Stevens Johnson syndrome. Aga Khan University Hospital over a 10 year period. All case records with a diagnosis of Steven Johnson Syndrome in the period 1990 to 2000 were retrospectively reviewed. Data was retrieved on a comprehensive questionnaire. The demographic variatbles and drugs taken within the previous 21 days were noted. Date analysis was done by Epi-Info Version 6.0. Of the 101 studied patient files, the most common offender was found to be the Penicillins as a group and Sulfadoxine-Pyrimethamine (Fansidar) when considering all drugs individually. Most common complications included electrolyte disturbances (13.9%) and congestive heart failure (6.9%). Mortality rate was high at 10.1%. SJS was found to be a rare condition but having a mortality rate of 10.1%. As it can be induced by a large number of drugs, caution should be practiced while prescribing.

  16. Permitting of Landfill Bioreactor Operations: Ten Years after ...

    Science.gov (United States)

    Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Outer Loop Landfill in Kentucky). In March 2014, there were about 40 bioreactor projects reported, including 30 active RD&D projects in 11 approved states and one project on tribal lands. Wisconsin features the largest number of projects at 13, due primarily to the fact that landfill owners in the state must either eliminate landfill disposal of biodegradable materials or to achieve the complete stabilization of deposited organic waste at MSW landfills within 40 years after closure. Most landfill operators have selected a bioreactor approach to attempt to achieve the latter goal. In summary, only 16 of 50 (32%) states have currently adopted the Rule, meaning that development of RD&D permitting procedures that are consistent with EPA’s requirements has generally not occurred. The predominant single reason cited for not adopting the Rule was lack of interest amongst landfill facilities in the state. Subtitle D and its state derivatives already allow leachate recirculation over prescriptive (i.e., minimum technology) liner systems, which is often the primary goal of site operators seeking to control leachate treatment costs. Other reasons related to concerns over increased time, cost

  17. Ten years at war: comprehensive analysis of amputation trends.

    Science.gov (United States)

    Krueger, Chad A; Wenke, Joseph C; Ficke, James R

    2012-12-01

    While multiple studies have examined amputations that have occurred during the current conflicts in Iraq and Afghanistan, none of these studies have provided an overarching characterization of all of these injuries. A retrospective study of all major extremity amputations sustained by US Service Members from January 2001 through July 30, 2011, was performed. Data obtained from these amputees included amputation level(s), mechanism of injury, time to amputation, Injury Severity Score (ISS), age, rank, number of trauma admissions, and number of troops deployed. There were 1,221 amputees who met inclusion criteria. These amputees sustained a total of 1,631 amputations. The number of amputations performed each year has increased dramatically in 2010 (196) and the first half of 2011 (160) from 2008 (105) and 2009 (94). The number of amputations performed per every 100 traumatic admissions (3.5-14) and the number of amputations per 100,000 deployed troops (2-14) has also increased in 2010 and the first half of 2011. Most amputations occurred at the transtibial (683, 41.8%) and transfemoral (564, 34.5%) levels. Thirty percent of the amputees (366) sustained multiple amputations, and 14% of all amputations (228) performed involved the upper extremity. There were 127 amputees (10%) who underwent their amputation more than 90 days after the date of injury. The number of amputations occurring during the current Iraqi and Afghanistan conflicts has increased in 2010 and the first half of 2011. Most amputations involve the lower extremities, and there is a much higher percentage of amputees who have sustained multiple amputations during current operations than previous conflicts. Epidemiologic study, level IV.

  18. Exploiting ten years of MERIS data over Land Surfaces

    Science.gov (United States)

    Gobron, Nadine

    2012-07-01

    that contains a detailed enough description of the terrestrial biosphere, it has been exploited for exploratory and diagnostic assessments of the biosphere through machine learning technique (Jung et al, 2010) and data assimilation technique (Kaminski at al, 2011). In this latter, the simultaneous assimilation of FAPAR and Carbon fluxes provides parameter estimates and uncertainty ranges that are consistent with the observational information. This works quantifies for the first time how MERIS products improve the accuracy of the current and future (net and gross) carbon flux estimates (within and beyond the assimilation period). Finally, the exploitation of MERIS data over land surfaces since 10 years has creating new area of research for the use of earth observation and is going towards new challenges for assessing the state of the global climate system.

  19. Ten-year follow-up of an anatomical hydroxyapatite-coated total hip prosthesis

    OpenAIRE

    Canales Cortés, V.; Panisello Sebastiá, J. J.; Herrera Rodríguez, A.; Peguero Bona, A.; Martínez Martín, A.; Herrero Barcos, L.; García-Dihinx, L.

    2006-01-01

    We report our results after ten year follow-up of 107 consecutive ABG-I hip prostheses implanted between June 1990 and December 1992: Only 84 prostheses were still in the study after ten years, but only six patients had undergone surgical revision. We can consider our clinical outcomes as excellent, with a whole-implant survival rate greater than 96%, a mean Merle D’Aubigne and Postel score increasing from 7.97 before operation to 16.17 at ten year follow-up, and a personal subjective assessm...

  20. Ten Years Back, Five Years Forward: The Data Seal of Approval

    Directory of Open Access Journals (Sweden)

    Ingrid Dillo

    2015-02-01

    Full Text Available If we want to share data, the long-term storage of those data in a trustworthy digital archive is an essential condition. Trust is the basis of storing and sharing data. That trust must be present in the various stakeholders involved. Certification of digital archives can make an important contribution to the confidence of these stakeholders in the digital archives.Ten years ago DANS was assigned the task of developing a Seal of Approval for digital data to ensure that archived data can still be found, understood and used in the future. In 2009 this Data Seal of Approval (DSA was transferred to an international body, the DSA Board, which has managed and further developed the guidelines and the peer review process ever since.The objectives of the DSA are to safeguard data, ensure high quality and guide reliable management of data for the future without requiring implementation of new standards, regulations or heavy investments. The DSA contains 16 guidelines for applying and verifying quality aspects concerning the creation, storage, use and reuse of digital data.Based on feedback from data archives that applied for a DSA and different case studies we have gained some insight into the benefits of DSA. Still, the impact of having the Seal is not easy to measure. Seal holders usually refer to qualitative benefits in the form of increased awareness of the value of their repositories to their communities, funders and publishers.Ten years down the line we can safely state that the Data Seal of Approval has proven its added value. If we try to look five years into the future, what can we expect? There are different developments: a growing interest in DSA among European research infrastructures, the collaboration between DSA and the ISCU World Data System under the umbrella of the RDA (Research Data Alliance and the European Commission is showing a growing interest in certification services.The success of DSA also provides the challenge to further

  1. Field experiments on seed dispersal by wind in ten umbelliferous species (Apiaceae)

    NARCIS (Netherlands)

    Jongejans, E.; Telenius, A.

    2001-01-01

    This report presents data from experiments on seed dispersal by wind for ten species of the family Apiaceae. Seed shadows were obtained in the field under natural conditions, using wind speeds between four and ten m/s. The flight of individual seeds was followed by eye, and seed shadows were

  2. Preliminary ten year results from a randomised single centre mass screening trial for abdominal aortic aneurysm

    DEFF Research Database (Denmark)

    Lindholt, Jes S.; Juul, Svend; Fasting, Helge

    2006-01-01

    analysis of the ten-year mortality from AAA, based upon population-based data until 2002 (7 years) and incomplete hospital-based information on deaths until 2005 (10 years). METHODS AND MATERIAL: In 1994 we started a randomised screening trial of 12,639 64-73 year-old males; 6,306 were controls, and 6...

  3. EXPERIENCIA DE AMIGDALECTOMIA EN LA FUNDACIÓN HOSPITAL DE LA MISERICORDIA DURANTE LOS &UOacute;LTIMOS DIEZ AÑOS Tonsillectomy experience in the Foundation “Hospital de la Misericordia Bogota” during the past ten years

    Directory of Open Access Journals (Sweden)

    Gilberto Eduardo Marrugo-Pardo

    2009-01-01

    procedure in Pediatric Otorhinolaryngology. This procedure is indicated for hypertrophied tonsils that causes airway obstruction, recurrent acute bacterial tonsillitis, asymmetric tonsils and peritonsillar abscess. It is an effective procedure and with little morbimorbidity. The most common complications are pain, bleeding, delay oral intake and velopharyngeal insufficiency. Objetive. To revise the experience during the last 10 years of tonsillectomy in Fundacion Hospital de La Misericordia. Materials and methods. Retrospective study, serie of cases, includes all patients who had tonsillectomy from May 2000 to February of 2009 in Fundacion Hospital de La Misericordia. The results were analyzed with the program SPSS16.0. Results. 149 patients were included in the analysis. Tonsillectomy was indicated for hypertrophied tonsils that causes airway obstruction in 45 percent of patients, recurrent tonsillitis and hypetrophied tonsils in 27,5 percent, recurrent tonsillitis in 11,4 percent, and asymmetric tonsils 6,7 percent. The technique performed in all patients was extracapsular tonsillectomy, using monopolar electrocautery in 97 percent and cold knife in 3 percent. The most common complications were pain in 41 percent, followed by otalgy 12,7 percent and bleeding 4 percent of the patients. The histological examination reported in most of them reactive follicular hyperplasia, except a case of Burkitt lymphoma whose indication was significant tonsillar asymmetry. Clinical improvement was seen in 96 percent of the patients. Conclusions. Tonsillectomy is a cost-effective and safe procedure. Under certain indications referred in this paper, tonsillectomy improves quality of life and good clinical course

  4. Early Predictors of Ten-Year Course in First-Episode Psychosis

    DEFF Research Database (Denmark)

    Friis, Svein; Melle, Ingrid; Johannessen, Jan Olav

    2016-01-01

    OBJECTIVE: Identifying patients at risk of poor outcome at an early stage of illness can aid in treatment planning. This study sought to create a best-fit statistical model of known baseline and early-course risk factors to predict time in psychosis during a ten-year follow-up period after a first...... psychotic episode. METHODS: Between 1997 and 2000, 301 patients with DSM-IV nonorganic, nonaffective first-episode psychosis were recruited consecutively from catchment area-based sectors in Norway and Denmark. Specialized mental health personnel evaluated patients at baseline, three months, and one, two......, five, and ten years (N=186 at ten years). Time in psychosis was defined as time with scores ≥4 on any of the Positive and Negative Syndrome Scale items P1, P3, P5, P6, and G9. Evaluations were retrospective, based on clinical interviews and all available clinical information. During the first two years...

  5. Randomized Trial of Treatment for Children with Sexual Behavior Problems: Ten-Year Follow-Up

    Science.gov (United States)

    Carpentier, Melissa Y.; Silovsky, Jane F.; Chaffin, Mark

    2006-01-01

    This study prospectively follows 135 children 5-12 years of age with sexual behavior problems from a randomized trial comparing a 12-session group cognitive-behavioral therapy (CBT) with group play therapy and follows 156 general clinic children with nonsexual behavior problems. Ten-year follow-up data on future juvenile and adult arrests and…

  6. Changing Course: Ten Years of Tracking Online Education in the United States

    Science.gov (United States)

    Allen, I. Elaine; Seaman, Jeff

    2013-01-01

    "Changing Course: Ten Years of Tracking Online Education" in the United States is the tenth annual report on the state of online learning in U.S. higher education. The survey is designed, administered and analyzed by the Babson Survey Research Group. Data collection is conducted in partnership with the College Board. This year's study, like those…

  7. Ten Years of Observatory Science from Saanich Inlet on the VENUS Cabled Ocean Observatory

    Science.gov (United States)

    Dewey, R. K.; Tunnicliffe, V.; Macoun, P.; Round, A.

    2016-02-01

    The Saanich Inlet array of the VENUS cabled ocean observatory, maintained and operated by Ocean Networks Canada, was installed in February 2006, and in 2016 will have supported ten years of comprehensive interactive science. Representing the first in the present generation of cabled observing technologies, this coastal array has provided continuous high power and broadband communications to a variety of instrument platforms, hundreds of sensors, and enabled dozens of short, medium, and long-term studies. Saanich Inlet is a protected fjord with limited tidal action, resulting in an extremely productive environment, with strong seasonal chemical variations driven by episodic deep water renewal events and oxygen reduction processes. The breadth of the research has included microbial and benthic community dynamics, biogeochemical cycles, forensics, quantifying inter-annual variations, benthic-pelagic coupling, sensor testing, plankton dynamics, and bio-turbulence. Observatory measurements include core water properties (CTD & O2) and water-column echo-sounder records, as well as experiment-oriented deployments utilizing cameras, Gliders, Dopplers, hydrophones, and a variety of biogeochemical sensors. With a recently installed Buoy Profiler System for monitoring the entire water column, community plans continue with a dedicated Redox experiment through the 2016-17 seasons. Highlights from the dozens of research papers and theses will be presented to demonstrate the achievements enabled by a comprehensive coastal cabled observing system.

  8. Ten Years in the Academic Integrity Trenches: Experiences and Issues

    Science.gov (United States)

    Atkinson, Doug; Nau, S. Zaung; Symons, Christine

    2016-01-01

    In 2016, our university launched its Academic Integrity Program (AIP) in order to promote and protect academic integrity. All commencing students must complete this online AIP within 14 days of starting their course. Satisfactory completion of this module with a test score of 80% is required before students can access their course materials.…

  9. Interventions and outcomes infetal hydrops - a ten year experience

    LENUS (Irish Health Repository)

    O'Sullivan, C

    2011-02-01

    Institute of Obstetricians & Gynaecologists, RCPI Four Provinces Meeting, Junior Obstetrics & Gynaecology Society Annual Scientific Meeting, Royal Academy of Medicine in Ireland Dublin Maternity Hospitals Reports Meeting, Nov 2010

  10. DITTY - a computer program for calculating population dose integrated over ten thousand years

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.

    1986-03-01

    The computer program DITTY (Dose Integrated Over Ten Thousand Years) was developed to determine the collective dose from long term nuclear waste disposal sites resulting from the ground-water pathways. DITTY estimates the time integral of collective dose over a ten-thousand-year period for time-variant radionuclide releases to surface waters, wells, or the atmosphere. This document includes the following information on DITTY: a description of the mathematical models, program designs, data file requirements, input preparation, output interpretations, sample problems, and program-generated diagnostic messages.

  11. Enamel microabrasion: 10 years experience.

    Science.gov (United States)

    Croll, T P

    1995-01-01

    Enamel microabrasion was developed in the mid 1980's as a method of eliminating enamel discolouration defects and improving the appearance of teeth. Ten years after the method was developed, much has been learned about the best technique, long term results of treatment and microscopic changes to the enamel surface that have distinguishable clinical implications. In addition, certain patients can benefit from combined enamel microabrasion/tooth bleaching therapy that yields the most attractive cosmetic results. This article reviews the current status of enamel microabrasion one decade after its introduction to the profession. The latest treatment protocol is presented and photographic case histories document results of treatment. Clinical observations made over ten years are discussed.

  12. The Aethereal Network on Chip after Ten Years: Goals, Evolution, Lessons, and Future

    NARCIS (Netherlands)

    Goossens, Kees; Hansson, A.

    2010-01-01

    The goals for the Æthereal network on silicon, as it was then called, were set in 2000 and its concepts were defined early 2001. Ten years on, what has been achieved? Did we meet the goals, and what is left of the concepts? In this paper we answer those questions, and evaluate different

  13. Theory-Based Evaluation: Reflections Ten Years On. Theory-Based Evaluation: Past, Present, and Future

    Science.gov (United States)

    Rogers, Patricia J.; Weiss, Carol H.

    2007-01-01

    This chapter begins with a brief introduction by Rogers, in which she highlights the continued salience of Carol Weiss's decade-old questions about theory-based evaluation. Theory-based evaluation has developed significantly since Carol Weiss's chapter was first published ten years ago. In 1997 Weiss pointed to theory-based evaluation being mostly…

  14. Quality of Life in South Africa--The First Ten Years of Democracy

    Science.gov (United States)

    Moller, Valerie

    2007-01-01

    South Africa celebrated ten years of democracy in 2004. This special issue of "Social Indicators Research" ("SIR") reviews developments that have impacted on the quality of life of ordinary South Africans during the transition period. The issue updates an earlier volume of "SIR" (Volume 41) published in 1997 and as a…

  15. Educational Virtual Environments: A Ten-Year Review of Empirical Research (1999-2009)

    Science.gov (United States)

    Mikropoulos, Tassos A.; Natsis, Antonis

    2011-01-01

    This study is a ten-year critical review of empirical research on the educational applications of Virtual Reality (VR). Results show that although the majority of the 53 reviewed articles refer to science and mathematics, researchers from social sciences also seem to appreciate the educational value of VR and incorporate their learning goals in…

  16. Acute lower abdominal pain caused by adnexal torsion in a ten-year-old girl

    DEFF Research Database (Denmark)

    Steinthorsdottir, Kristin Julia; Hansen, Lars Folmer; Bisgaard, Thue

    2014-01-01

    A ten-year-old girl presented with four days of lower abdominal pain. A diagnostic laparoscopy on the suspicion of acute appendicitis revealed left-sided adnexal torsion. The cyanotic ovary was detorsed and recovered. At three-month follow-up there were no clinical or ultrasonic signs of pathology...

  17. Ten years after the Jali Commission Assessing the state of South ...

    African Journals Online (AJOL)

    Ten years have lapsed since the Jali Commission's final report became publicly available, and it is therefore an opportune time to assess the state of South Africa's prison system. The Jali Commission was appointed when it became clear that the state had lost control of the Department of Correctional Services (DCS).

  18. Ten-year mortality review in a pioneer psychiatric hospital in West ...

    African Journals Online (AJOL)

    Objective: To determine the mortality among admitted patients in the study centre, a pioneer psychiatric facility in the West African sub-region. Design: A detailed retrospective study of the records of all deaths among the inpatients during the ten-year period of January, 1991 to December, 2000. Setting: Psychiatric Hospital ...

  19. Survival and vigour of ultra-dry seeds after ten years of hermetic storage

    NARCIS (Netherlands)

    Hong, T.D.; Ellis, R.H.; Astley, D.; Pinnegar, A.E.; Groot, S.P.C.; Kraak, H.L.

    2005-01-01

    Seeds of carrot, groundnut, lettuce, oilseed rape and onion were stored hermetically in laminated aluminium foil packets in four environments (dry or ultra-dry moisture contents combined factorially with temperatures of 20 degrees C or -20 degrees C), replicated at several sites. After ten years'

  20. Ten Years of bored tunnels in the Netherlands : Part I: Geotechnical issues

    NARCIS (Netherlands)

    Bakker, K.J.; Bezuijen, A.

    2008-01-01

    Ten years have passed since in 1997 for the first time construction of bored tunnels in the Netherlands soft soil was undertaken. Before that date essentially only immersed tunnels and cut-and-cover tunnels were constructed in the Netherlands. The first two bored tunnels were Pilot Projects, the 2nd

  1. Mechanical birth injuries in the Niger Delta: a ten-year review (1989 ...

    African Journals Online (AJOL)

    Mechanical birth injuries in the Niger Delta: a ten-year review (1989-1998). Cosmos E Enyindah, Alice R Nte. Abstract. Context: Birth traumas associated with poor obstetric services contribute significantly not only to the high perinatal morbidity and mortality, but also to long-term sequelae in the survivors in many developing ...

  2. Transverse patella fracture in a ten year old boy: case report ...

    African Journals Online (AJOL)

    Patella fractures are rare in children. Transverse fractures in particular are an uncommon pattern. We report a case of a transverse patella fracture in a ten year old boy. He presented with inability to actively extend his left knee, two months after a fall. On evaluation he was found to have a transverse fracture of his left patella.

  3. Careers as Viewed by Five and Ten Year Graduates of Home Economics and Journalism Programs.

    Science.gov (United States)

    Crumley, Wilma; Sailor, Patricia

    This study examined the reactions of women who chose a traditional career (home economics) and women who chose a nontraditional career (journalism) five and ten years after graduation. The study included 171 home economics graduates and 75 journalism graduates. Of these, 36 were males and 210 females. Sixty-eight graduated in 1965 and 178 in 1969.…

  4. Mathematical Skills in Undergraduate Students. A Ten-Year Survey of a Plant Physiology Course

    Science.gov (United States)

    Llamas, A.; Vila, F.; Sanz, A.

    2012-01-01

    In the health and life sciences and many other scientific disciplines, problem solving depends on mathematical skills. However, significant deficiencies are commonly found in this regard in undergraduate students. In an attempt to understand the underlying causes, and to improve students' performances, this article describes a ten-year survey…

  5. Historical Evolution of Instructional Technology in Teacher Education Programs: A Ten-Year Update

    Science.gov (United States)

    Betrus, Anthony

    2012-01-01

    The content and emphasis of the introductory technology courses for undergraduate preservice teachers has historically been examined, with the earliest study conducted by Stracke in 1932. In an attempt to identify trends in the course DeKieffer conducted a series of studies over ten year intervals, in 1947, 1957, 1967, and 1977. In 2000 the first…

  6. The AES total ankle arthroplasty analysis of failures and survivorship at ten years.

    Science.gov (United States)

    Di Iorio, Alexandre; Viste, Anthony; Fessy, Michel Henry; Besse, Jean Luc

    2017-09-04

    AES mobile-bearing total ankle replacement was developed from the Buechel Pappas model. It was withdrawn in 2009, after identification of a higher than expected complication rate. The purpose of the current study was to analyse clinical outcomes, failures and survival of the initial series of 50 AES published in 2009. In this single-centre continuous prospective study (2003-2006), 50 AES prostheses were included. Pre-operative osteoarthritis was mainly post-traumatic (50%) and secondary to instability (36%). All patients were assessed with clinical and radiographic follow-up at six months, one year, two years and every two to three years thereafter. A CT-scan was systematically performed before procedure, and at two years, five years and ten years. At last follow-up, all patients with TAR had a functional (SF 36, AOFAS) and clinical assessment. All complications or surgical events were analysed. The mean follow-up was ten ± two years (range, 9-13). The mean AOFAS score was 75 points (range, 26-100). The mean SF 36 score was 69 points (range, 35-97). There was a significant deterioration in AOFAS score at five years and at last follow-up (p < 0.05). Fifteen TARs underwent reoperation for cyst curettage-graft because of development of periprosthetic lesions. Six of them ended up with prosthesis removal-arthrodesis. At the last follow-up, 14 TARs were removed for arthrodesis. Of the 30 prostheses seen at last follow-up, four are awaiting prosthesis removal-arthrodesis and one for cyst curettage-graft. The ten year survivorships free of any prosthesis removal or arthrodesis and free of any reoperation were 68% (95% CI, 55-85) and 57% (95% CI, 44-74), respectively. Our data suggested a high rate of reoperation. Overall ten year survival was lower than with other designs, particularly due to cyst lesions. Level IV, prospective case series.

  7. Adolescent cancer patients' perspectives on their educational experiences: Ten case studies

    Science.gov (United States)

    Searle, Nancy Smith

    The goal of this study was to explore the educational experiences of adolescent cancer patients in treatment for cancer and enrolled in hospital, homebound, or community schools. The incidence of students who have or had cancer is becoming more prevalent in schools today because of increases in the population, the incidence rate of cancer, and the survival rate of cancer. The number of students surviving cancer has increased over 41% in the past ten years and underscores the importance of assuring an excellent education to children and adolescents with cancer so that they may enjoy a good quality of life as long-term survivors. This study explored the educational experiences of students who were adolescent cancer patients and identified educational and psychosocial issues important to their success. The goal of this research effort was to provide educators and medical staff with a deeper understanding of the unique psychoeducational needs of this population and to provide a foundation for developing ideas for improving the educational programs and support available to students who continue their middle and high school education while undergoing treatment for cancer. Participants included ten cancer patient whose mean age at onset of disease was 13.8 +/- 1.7 years, and mean age at interview was 15.2 +/- 1.8 years. The researcher conducted individual, in-depth, ethnographic interviews of students, and one parent and one teacher of each student. Case studies of the students included extensive dialogue of each of the contributing participants. An analysis of the case studies was conducted by coding emerging themes so that topics could be fully explored and compared between individuals, groups of individuals, and educational settings to identify the meaning that these students placed on the educational and psychosocial issues that they voiced as important. Advantages and disadvantages of each educational situation, homebound, hospital school, and community school, were

  8. Do Estrogens improve bone mass in osteoporotic women over ten years of menopause

    Directory of Open Access Journals (Sweden)

    Vera Lucia Szejnfeld

    Full Text Available A retrospective analysis of 24 patients with established osteoporosis and with ten or more years of menopause treated with conjugated estrogen, progesterone and calcium followed for one year has been performed. Treated women received 0.625 mg/day of conjugated estrogen from day 1 to 25, 5 mg/day of medroxiprogesterone from day 13 to 25, of each cycle, plus calcium (500 - 1000 mg/day, during one year (12 cycles. As control group was used 18 age-matched that received only calcium (500 a 1000 mg/day. All patients had at least two dual-photon spine and proximal femur (neck, Ward's triangle and trocanter densities measurements performed 12 months apart. Estrogen treatment was associated with increased bone mineral density at spine and trocanter. Control group did not present any statistically change after one year in any site studied. We concluded that women with ten or more years of menopause and established osteoporosis treated with replacement hormonal therapy and calcium results in improvement of bone mineral density. These data support that women with ten or more years of menopause respond to estrogen replacement therapy with absolute increments in bone density similar to those seen in younger women, in the early menopause.

  9. [Competent and diverse. Portrayal of older adults in Dutch television commercials ten years later].

    Science.gov (United States)

    van Selm, M; Westerhof, G J; de Vos, B

    2007-05-01

    The present study replicates our study of older adults' portrayal in Dutch television commercials conducted in 1993. The central question is whether older adults are being portrayed more visibly in Dutch television commercials and whether this portrayal has become more diverse compared to ten years ago. Based on a list of descriptions of all commercials broadcasted by public television channels in 2003 (N= 4767) 117 commercials featuring older adults were selected. By means of a quantitative content analysis it was examined whether and how older men and women are portrayed. It was concluded that although older adults are not more prevalent compared to ten years ago, their portrayal is more diverse with respect to their roles and the advertised products. Older adults were portrayed as more competent and less age-stereotypical in television commercials.

  10. A prospective ten-year follow-up of patients with chronic urticaria.

    Science.gov (United States)

    Dionigi, P C L; Menezes, M C S; Forte, W C N

    2016-01-01

    Chronic urticaria can be the initial clinical presentation of a number of different diseases. The objective of the present study was to report the associated diseases during a ten-year clinical-laboratory follow-up in patients with an initial diagnosis of chronic spontaneous urticaria (CSU) of unknown cause. A prospective, longitudinal cohort study with a ten-year clinical-laboratory follow-up was conducted. Patients with a history of urticarial plaques of over six weeks presenting as the only clinical symptom were selected. Individuals with other clinical conditions, urticaria of known causes or chronic physical urticaria were excluded. The following tests were initially performed: haemogram, urine type I, stool parasite exam and sedimentation rate. The following exams were ordered during follow-up: PPD; urine culture; serology tests; antithyroid and antinuclear antibodies, rheumatoid factor, lupus anticoagulant; thyroid hormones; serum immunoglobulin; paranasal sinus and thorax radiographs; testing for BK and Helicobacter pylori; and prick tests. Infections were diagnosed in 29% of patients (syphilis, parasitosis, H. pylori, urinary infection, tuberculosis, hepatitis B and C); autoimmune diseases in 21% (thyroiditis, rheumatoid arthritis and antiphospholipid antibody syndrome); primary immunodeficiencies in 4% (IgA and IgG2 deficiencies); and chronic myeloid leukaemia in 1%. At ten-years of follow-up, the urticaria diagnosis was CSU of unknown cause in 45% of the cases. This ten-year clinical-laboratory follow-up of 100 individuals with chronic urticaria as the initial diagnosis revealed the presence of associated diseases in over half of the cases. The most prevalent diseases were infections and autoimmune diseases besides primary immunodeficiencies and blood diseases. Copyright © 2016 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.

  11. Ten Years of Monitoring 3C 273 with XMM–Newton Liu Liu ...

    Indian Academy of Sciences (India)

    Abstract. We present ten years optical/UV/X-ray observations of 3C. 273 performed using XMM–Newton between 2000 and 2009. The short- time scale variability behaviour of the soft and hard X-ray light curves may suggest different origins of the soft/hard X-ray emissions. We fit well the 0.2–10 keV X-ray spectrum with a ...

  12. Ten Years of Monitoring 3C 273 with XMM–Newton

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... We present ten years optical/UV/X-ray observations of 3C 273 performed using XMM–Newton between 2000 and 2009. The short-time scale variability behaviour of the soft and hard X-ray light curves may suggest different origins of the soft/hard X-ray emissions. We fit well the 0.2–10 keV X-ray spectrum ...

  13. Compromises in orchestra pit design: A ten-year trench war in The Royal Theatre, Copenhagen

    DEFF Research Database (Denmark)

    Gade, Anders Christian; Mortensen, Bo

    1998-01-01

    years this new flexibility caused a formal battle between the orchestra, the singers, and management, because each group had different interests as to how the pit should be configured for each new production. In the 1990s, increased concern about the musicians' hearing and the increase in the popularity...... of opera finally opened the way for a new renovation of the pit, which solved most of the problems. The paper describes the many lessons learned during the ten-year period in which the authors were involved with the case as acoustic consultants. Questions of how pit configuration influences mutual hearing...

  14. Moving Upstream and Going Local: The Responsibility to Protect Ten Years Later

    Directory of Open Access Journals (Sweden)

    Bridget Moix

    2015-10-01

    Full Text Available Ten years ago the international community pledged to protect civilians from genocide, ethnic cleansing, war crimes, and crimes against humanity by endorsing the responsibility to protect (R2P doctrine. Yet today, horrific violence against civilians continues in places like Syria, Iraq, and South Sudan. This article examines some of the progress and gaps in the international community’s efforts to better protect civilians against mass violence over the past decade. It proposes two emerging directions for advancing the R2P agenda in the coming years: 1 greater focus on upstream prevention, and 2 increased support for locally-led peacebuilding and prevention actors and capacities.

  15. Idaho National Laboratory 2013-2022 Ten-Year Site Plan

    Energy Technology Data Exchange (ETDEWEB)

    Calvin Ozaki; Sheryl L. Morton; Elizabeth A. Connell; William T. Buyers; Craig L. Jacobson; Charles T. Mullen; Christopher P. Ischay; Ernest L. Fossum; Robert D. Logan

    2011-06-01

    The Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of transforming the laboratory to meet Department of Energy (DOE) national nuclear research and development (R&D) goals, as outlined in DOE strategic plans. The plan links R&D mission goals and INL core capabilities with infrastructure requirements (single- and multi-program), establishs the 10-year end-state vision for INL complexes, and identifies and prioritizes infrastructure needs and capability gaps. The TYSP serves as the basis for documenting and justifying infrastructure investments proposed as part of the FY 2013 budget formulation process.

  16. Ten years of democracy: attitudes and identity among some South African school children

    Directory of Open Access Journals (Sweden)

    Charlyn Dyers

    2011-08-01

    Full Text Available Ten years into South Africa’s democracy, how do school children feel about themselves as part of specific groups, and what is the role of language in their socio-cultural identities? This paper looks at the ways in which two groups of fourteen-year-old Xhosa-speaking and mixed-race ‘Coloured’ South African secondary school learners in a new housing area near Cape Town negotiate their identities through language in a context of rapid social change. It analyses their beliefs and attitudes about the languages and speech communities to which they are exposed.

  17. Creative Climate: A global ten-year communications, research and learning project about environmental change

    Science.gov (United States)

    Brandon, M. A.; Smith, J.

    2010-12-01

    The next ten years have been described by influential science and policy figures as ‘the most important in human history’. Many believe that the actions taken will decide whether we catastrophically change the atmosphere and eradicate our fellow species or find an alternative, less-damaging development path. But communications and public engagement initiatives have tended to focus on near term impacts or debates - whether they emphasise hazards, or trumpet ‘solutions’. There are signs of diminishing returns on communications and public engagement efforts, and serious obstacles to engaging around 40% of publics in e.g. the US and the UK. The Creative Climate web project takes a new approach, inviting people to see humanity’s intellectual and practical journey with these issues as an inspiring, dynamic and unfolding story. We are inviting people to join us in building a huge living archive of experiences and ideas that respond to these issues. The website will collect thoughts and stories from doorstep to workplace, from lab to garden; from international conference to community meeting - from all over the world. The body of diaries lie at the core of the project, but these are supplemented by the offer of free online learning resources and broadcast-quality audio and video materials. The project is experimental in terms of its scope, its approach to environmental communications and debate and in its use of media. It works with formal partners, including the BBC, yet also makes the most of the opportunities for user generated content to create a rich multimedia resource that can support research, learning and engagement. The design of the project is informed by environmental social science and communications research, and by an awareness of the unfolding potential of Internet based communications to support social change. It is also intended that the Creative Climate platform will develop so as to serve researchers by offering an open resource of qualitative

  18. A ten year audit of maternal mortality: Millennium development still a distant goal

    Directory of Open Access Journals (Sweden)

    Anshuja Singla

    2017-01-01

    Full Text Available Objective: To assess various causes of maternal mortality over a ten year period Design: Retrospective audit of hospital case records Setting: Tertiary care hospital Population: Pregnant women who expired in the premises of GTB Hospital. Materials and Methods: A retrospective audit of case records of maternal deaths was conducted for a ten year period (January 2005 to December 2014. Results: There were a total of 647 maternal deaths out of 1,16,641 live births. Sixty-eight percent (n = 445 of women were aged 21-30 years, while 10.5% (n = 68 were <20 years of age. The most common direct causes of maternal mortality were preeclampsia/eclampsia in 24.4% (n = 158, obstetric hemorrhage in 19.1% (n = 124 and puerperal sepsis in 14.5% (n = 94. With regards to indirect causes, anemia accounted for 15.3% (n = 99 mortality. There was only 1 (0.1% mortality because of HIV/AIDS. Other notable causes of maternal mortality were infective hepatitis in 7.1% (n = 46. Tuberculosis, that is a disease of tropical countries, accounted for 3.0% (n = 20 of the total deaths. Conclusion: High maternal mortality in GTB hospital can be due to it being a tertiary hospital with referrals from all neighbouring states. Accessible antenatal care can help prevent these maternal deaths. Female education can be of immense help in dealing with the problem and improving the utilization of public health facilities.

  19. Comparison of the refractive error changes among young children in ten years interval

    Directory of Open Access Journals (Sweden)

    Hai-Yan Li

    2013-07-01

    Full Text Available AIM: To compare the optometric examination results of myopic young children between those diagnosed in the period from 1998 to 2000 and those diagnosed in the period from 2008 to 2010; and to find out the causes of myopia and factors that worsen the condition, and suggest methods of its prevention and treatment.METHODS: This study was a retrospective case study. We randomly selected sample from out-patient department register of cases and divided them into two main groups, ‘ten year before group'(TYBG(1998/2000 year casesand ‘ten years later group'(2008/2010 year cases(TYLG. Each group was further subdivided into three sub-groups by age: under-six years old children group(CG, seven-twelve years old primary-school group(PSGand thirteen-eighteen years old middle-school group(MSG. The optometric examination results were statistically analyzed.RESULTS: The difference of the mean dioptre between the TYBG and TYLG was strongly statistically significant, also forward-lead trend of age when children suffered from myopia was found(P0.01. There was a significant increase of dioptre among PSG and MSG in TYLG compared to TYBG(PCONCLUSION: Our study shows that the age of getting myopia was forward lead, the dioptre increases by 1.00 degree and the prevalence of myopia is increasing gradually. This situation may due to the modern life style and changes of living standard of the population. Therefore, prevention of myopia should concentrate more on younger children at kindergarten and primary school stage students.

  20. Spontaneous Mediastinitis in a Ten-year-old Girl: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Kyung Eun; Kim, Ji Hong; Yoon, Choon Sik [Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of); Lee, Mi Jung; Kim, Myung Joon [Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of)

    2011-01-15

    Acute suppurative mediastinitis is an uncommon, life threatening condition with a mortality rate of up to 40%. It is mainly caused by esophageal perforation or post-operative complications, and acute mediastinitis not caused by trauma or surgery is rare. To the best of our knowledge, no cases of spontaneous mediastinal abscess in children have been reported in the English medical literature. We report here on a case of an acute mediastinal abscess in a ten-year-old girl and there was no demonstrable clinical or radiologic etiology for infection

  1. Plant and equipment division laboratory services series: a ten-year building-maintenance cost history

    Energy Technology Data Exchange (ETDEWEB)

    Keesee, H.F.

    1976-09-01

    Maintaining a multifacility national laboratory in a safe, reliable condition is a complex management responsibility in terms of budgets, costs, and proper utilization of personnel and material resources. Increasing wage rates and material costs, combined with decreased budgets and aging facilities, create unusual challenges to maintenance managers. A ten-year history of building-maintenance costs, a brief description of the maintenance program, analyses of personnel requirements, cost increase indexes, unit costs, cost controls, procedures, and a brief discussion of alterations and improvements are presented.

  2. Colorectal carcinoma in a ten-year-old girl: A case report

    Directory of Open Access Journals (Sweden)

    Sarbani Chattopadhyay

    2012-01-01

    Full Text Available Colorectal carcinoma is very rare in childhood. In this case report, we depict a ten-year-old girl who presented with features of intestinal obstruction which turned out to be due to poorly differentiated mucin secreting adenocarcinoma of descending colon. Only increased awareness of this malignancy in this age-group and a high index of suspicion can help when a child complains of persistent pain of abdomen, altered bowel habits or rectal bleeding, and may provide diagnosis at an earlier stage, thereby improving the prognosis.

  3. Ten years of forensic odontology: a report from the Department of Forensic Odontology, Stockholm, Sweden.

    Science.gov (United States)

    Teivens, A; Mornstad, H

    1992-12-01

    The practical activities of the Department of Forensic Odontology at the National Board for Forensic Medicine in Stockholm, Sweden, have been reviewed over a ten year period (1980-1989). The number of cases has increased from 72 in 1980 to 278 in 1989, and a total of 1402 tasks have been carried out. Seventy-five per cent of the cases have concerned identification of single individuals, 14% have involved the National Register of Missing Persons with the remaining cases being age determination (34), bite marks (27), oral examination after criminal assault (69), examination of skeletal remains, dentures, restorative materials (33) and written reports to be presented at court (159).

  4. Ten Years of GWOT, the Failure of Democratization, and the Fallacy of

    Directory of Open Access Journals (Sweden)

    David Oakley

    2012-01-01

    Full Text Available October 7, 2011, marked a decade since the United States invaded Afghanistan and initiated the Global War on Terrorism (GWOT. While most ten-year anniversary gifts involve aluminum, tin, or diamonds, the greatest gift U.S. policymakers can present American citizens is a reconsideration of the logic that guides America's counterterrorism strategy. Although the United States has successfully averted large-scale domestic terrorist attacks, its inability to grasp the nature of the enemy has cost it dearly in wasted resources and, more importantly, lost lives. Two of the most consistent and glaring policy flaws revolve around the concepts of filling "ungoverned spaces" and installing democracy by force.

  5. Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

    DEFF Research Database (Denmark)

    Ten Velden Hegelstad, Wenche; Haahr, Ulrik; Larsen, Tor K

    2013-01-01

    Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years.......Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years....

  6. Idaho National Laboratory 2015-2023 Ten-Year Site Plan

    Energy Technology Data Exchange (ETDEWEB)

    Sheryl Morton; Elizabeth Connell; Bill Buyers; John Reisenauer; Rob Logan; Chris Ischay; Ernest Fossum; Paul Contreras; Joel Zarret; Steve Hill; Jon Tillo

    2013-09-01

    This Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of sustaining the INL infrastructure to meet the Department of Energy Office of Nuclear Energy (DOE-NE) mission: to promote nuclear power as a resource capable of making major contributions in meeting the nation’s energy supply, environmental and energy security needs. This TYSP provides the strategy for INL to accomplish its mission by: (1) linking R&D mission goals to core capabilities and infrastructure requirements; (2) establishing a ten-year end-state vision for INL facility complexes; (3) identifying and prioritizing infrastructure needs and capability gaps; (4) establishing maintenance and repair strategies that allow for sustainment of mission-critical (MC) facilities; and (5) applying sustainability principles to each decision and action. The TYSP serves as the infrastructure-planning baseline for INL; and, though budget formulation documents are informed by the TYSP, it is not itself a budget document.

  7. Floridi’s “Open Problems in Philosophy of Information”, Ten Years Later

    Directory of Open Access Journals (Sweden)

    Gordana Dodig Crnkovic

    2011-05-01

    Full Text Available In his article Open Problems in the Philosophy of Information [1] Luciano Floridi presented a Philosophy of Information research program in the form of eighteen open problems, covering the following fundamental areas: Information definition, information semantics, intelligence/cognition, informational universe/nature and values/ethics. We revisit Floridi’s program, highlighting some of the major advances, commenting on unsolved problems and rendering the new landscape of the Philosophy of Information (PI emerging at present. As we analyze the progress of PI we try to situate Floridi’s program in the context of scientific and technological development that have been made last ten years. We emphasize that Philosophy of Information is a huge and vibrant research field, with its origins dating before Open Problems, and its domains extending even outside their scope. In this paper, we have been able only to sketch some of the developments during the past ten years. Our hope is that, even if fragmentary, this review may serve as a contribution to the effort of understanding the present state of the art and the paths of development of Philosophy of Information as seen through the lens of Open Problems.

  8. Ten years of telerehabilitation: A literature overview of technologies and clinical applications.

    Science.gov (United States)

    Rogante, Marco; Grigioni, Mauro; Cordella, Daniele; Giacomozzi, Claudia

    2010-01-01

    This paper aims at delivering a structured overview of telerehabilitation literature by analysing the entire set of articles under the search terms "telerehabilitation" or "tele-rehabilitation" to portray "state of the art" ten years after the publication of the first scientific article on the topic. A structured study has been conducted by considering all those articles containing the word "telerehabilitation" or "tele-rehabilitation". Medline, Embase, Cochrane, UK Centre for Reviews and Dissemination, Canadian Agency for Drugs and Technologies in Health databases have been interrogated for articles between 1998 and 2008. 146 scientific articles were found. 56 articles focus on patient treatment, 23 are reviews, 3 are to be considered as both patient treatment papers and reviews, 53 are either technical reports, system descriptions or analyses of new approaches; 8 are general discussion on telerehabilitation. The present paper draw the scenario of the first ten years of telerehabilitation, focussing on clinical applications and technologies. Basically, it confirms the lack of comprehensive studies providing evidence for supporting decision and policy-makers in adopting telerehabilitation technologies in the clinical practice. An overall lack of standardisation in the used terminology also results from the analysis of keywords, which is typical of quite recent fields of application.

  9. Ten-year results of phototherapeutic keratectomy on recurrent corneal erosions

    Directory of Open Access Journals (Sweden)

    Belquiz Rodrigues do Amaral Nassaralla

    2012-02-01

    Full Text Available PURPOSE: To determine the ten-year visual results and outcomes of excimer laser phototherapeutic keratectomy (PTK for recurrent corneal erosions. METHODS: Twenty-six eyes of 23 patients with recurrent corneal erosions were treated by PTK from 1996 to 2000 at the Goiania Eye Institute, Brazil. All eyes had failed to respond to conventional therapy. Data regarding preoperative and postoperative best-spectacle-corrected visual acuity (BSCVA, spherical equivalent (SE, symptomatic relief, incidence of recurrence, and complications arising from the laser treatment were analyzed. The mean duration of symptoms prior to PTK was 18 months (range, 8 to 36 months. The corneal epithelium was debrided, and laser ablation was performed to a depth of 5 micron with an ablation zone of 7 to 9 mm, using the Technolas 217C Plano Scan excimer laser. Mean postoperative follow-up was 12 years (range, 10 to 14 years. RESULTS: At the last follow-up visit, 15 eyes (57.69% were symptomsfree. Five eyes (19.2% had occasional mild symptoms of irritation and photophobia upon awakening. Recurrence of painful corneal erosions occurred in six eyes (23.07%, which required a PTK retreatment. Twenty-four eyes had a preserved or improved BCVA, while 2 eyes showed deterioration of 1 line on Snellen test. Eleven eyes (42.3% had no change in SE, and the others (57.69% had a change of less than +/-0.75 diopters (D. There were no major complications during the follow-up period. CONCLUSION: Ten-year data show that PTK is a safe, fast, effective and minimal invasive choice of treatment for recurrent corneal erosions in patients who do not respond to conventional treatments.

  10. Dez anos de experiência com cirurgia micrográfica pelo método de Munique: relato de 93 casos operados A ten-year experience with the Munich method of micrographic surgery: a report of 93 operated cases

    Directory of Open Access Journals (Sweden)

    Luis Fernando Figueiredo Kopke

    2005-12-01

    Full Text Available FUNDAMENTOS: A cirurgia de Mohs é um dos métodos mais eficazes de tratamento dos carcinomas basocelulares. A expansão de seus conceitos possibilitou o surgimento de outros métodos de checagem de margens cirúrgicas igualmente eficazes. O método de Munique é um exemplo disso. OBJETIVOS: Avaliar a eficácia da cirurgia micrográfica pelo método de Munique em um estudo de coorte com 10 anos de duração. MÉTODOS: 93 pacientes com 96 tumores cutâneos foram tratados com cirurgia micrográfica pelo método de Munique, participando de um protocolo de acompanhamento, no período de maio de 1994 a julho de 2004. RESULTADOS: 61,4% dos tumores eram recidivados; 42,3% eram recidivados mais de uma vez; 53% eram do tipo esclerodermiforme. A média do maior diâmetro dos tumores foi de 1,58cm e do menor 1,10cm. Em 95% dos casos se obteve a extirpação total do tumor, com até três estágios. A localização mais comum foi a nasal (46,3%, seguida da periocular (18,9% e da frontal (11,5%. Perdeu-se o contato apenas com dois pacientes. Dos 96 tumores operados, apenas 11 têm tempo de seguimento inferior a dois anos. 56 pacientes foram seguidos por pelo menos cinco anos, e 45 (47,3%, por mais de seis anos. Apenas um caso de recidiva foi verificado, tendo ocorrido no sexto ano de observação. CONCLUSÃO: O método de Munique é um método eficiente de cirurgia micrográfica, tanto quanto o método de Mohs. Este trabalho fornece mais um indício de que o conceito de cirurgia micrográfica deve ser ampliado para cirurgia microscopicamente controlada, e não ficar ligado estritamente ao termo cirurgia de Mohs.BACKGROUND: Mohs surgery is one of the most effective treatments for basal cell carcinomas. The expansion of its concepts enabled developing other equally effective methods to check surgical margins, and the Munich method is an example. OBJECTIVES: To evaluate the effectiveness of the Munich method of micrographic surgery in a ten-year cohort study

  11. Ten Years, Twenty Issues, and Two Hundred Papers of Numeracy: Toward International Reach and Transdisciplinary Utility

    Directory of Open Access Journals (Sweden)

    H.L. Vacher

    2017-07-01

    Full Text Available This issue completes the first ten years of Numeracy. The purpose of this introductory editorial is to review what has happened to the journal in those ten years. In the twenty issues, Numeracy’s output has been 201 papers counting the one or two editorials per issue. More than 50% of the papers are full, peer-reviewed articles, including 13 papers in two theme collections. The others are peer-reviewed notes and perspectives, editor-reviewed book reviews (15% of the total, and a column by contributing co-editor, Dorothy Wallace. The current issue marks an upswing in the number of notes, and our first discussion/reply. The number of papers per year has been increasing (e.g., 66% more in the last three years than in the first three years. The download rate has increased from about 5,000 in the first two years to 5,000 in about 40 days now. The editorial goes on to document two main outcomes. First, the journal is gaining an international reach: more than half the downloads occur outside the United States now, and the number of contributions from outside the United States has increased from 4 in the first five years to 15 in the second five years. Second, the across-the-curriculum nature of quantitative literacy is coming to the fore. The transdisciplinarity of QL is strikingly evident in this issue, which is discussed in some detail, especially how it conforms to the mission of the Association of American Colleges and Universities. The editorial ends with some results from a small ad hoc study of Google Scholar Citation Profiles. The question was, of the profiles that used “numeracy” or “quantitative literacy” as keywords, what other keywords did those profiles use, and what were the source countries? The results show that (1 QL is very much an American term, (2 there is, metaphorically, a vast and interesting numeracy ecosystem out there for Numeracy to engage and serve, and (3 as we become more global, the transdisciplinary relevance

  12. Introduction to "Tsunami Science: Ten Years After the 2004 Indian Ocean Tsunami. Volume I"

    Science.gov (United States)

    Rabinovich, Alexander B.; Geist, Eric L.; Fritz, Hermann M.; Borrero, Jose C.

    2015-03-01

    Twenty-two papers on the study of tsunamis are included in Volume I of the PAGEOPH topical issue "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami." Eight papers examine various aspects of past events with an emphasis on case and regional studies. Five papers are on tsunami warning and forecast, including the improvement of existing tsunami warning systems and the development of new warning systems in the northeast Atlantic and Mediterranean region. Three more papers present the results of analytical studies and discuss benchmark problems. Four papers report the impacts of tsunamis, including the detailed calculation of inundation onshore and into rivers and probabilistic analysis for engineering purposes. The final two papers relate to important investigations of the source and tsunami generation. Overall, the volume not only addresses the pivotal 2004 Indian Ocean (Sumatra) and 2011 Japan (Tohoku) tsunamis, but also examines the tsunami hazard posed to other critical coasts in the world.

  13. Introduction to "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami. Volume II."

    Science.gov (United States)

    Rabinovich, Alexander B.; Geist, Eric L.; Fritz, Hermann M.; Borrero, Jose C.

    2015-12-01

    Twenty papers on the study of tsunamis and respective tsunamigenic earthquakes are included in Volume II of the PAGEOPH topical issue "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami". The papers presented in this second of two special volumes of Pure and Applied Geophysics reflect the state of tsunami science during this time, including five papers devoted to new findings specifically in the Indian Ocean. Two papers compile results from global observations and eight papers cover Pacific Ocean studies, focusing mainly on the 2011 Tohoku earthquake and tsunami. Remaining papers in this volume describe studies in the Atlantic Ocean and Mediterranean Sea and tsunami source studies. Overall, the volume not only addresses the pivotal 2004 Indian Ocean and 2011 Tohoku tsunamis, but also examines the tsunami hazard posed to other critical coasts in the world.

  14. A ten-year search for synchronous cells: obstacles, solutions and practical applications

    Directory of Open Access Journals (Sweden)

    Charles Edward Helmstetter

    2015-03-01

    Full Text Available My effort to use synchronously dividing cultures to examine the Escherichia coli cell cycle involved a ten-year struggle with failure after failure punctuated by a few gratifying successes, especially at the end. In this essay, I recount my personal journey in this obsessive experimental pursuit. That narrative is followed by a description of a simplified version of the baby machine, a technique that was developed to obtain minimally disturbed, synchronously growing E. coli cells. Subsequent studies with this methodology led to an understanding of the basic properties of the relationship between chromosome replication and cell division. Accordingly, I end this reminiscence with a simple, fool-proof graphical strategy for deducing the pattern of chromosome replication during the division cycle of cells growing at any rate.

  15. The State of the Art Ten Years After a State of the Art

    DEFF Research Database (Denmark)

    Sturm, Bob L.

    2014-01-01

    A decade has passed since the first review of research on a ``flagship application" of music information retrieval (MIR): the problem of music genre recognition (MGR). During this time, about 500 works addressing MGR have been published, and at least 10 campaigns have been run to evaluate MGR sys......, the problems of validity in evaluation also affect research in music emotion recognition and autotagging. We conclude by discussing the implications of our work for MGR and MIR in the next ten years.......A decade has passed since the first review of research on a ``flagship application" of music information retrieval (MIR): the problem of music genre recognition (MGR). During this time, about 500 works addressing MGR have been published, and at least 10 campaigns have been run to evaluate MGR...

  16. The church and society in South Africa celebrating first ten years of democracy (1994-2004

    Directory of Open Access Journals (Sweden)

    R T H Dolamo

    2005-10-01

    Full Text Available In this article, colonialism, slavery, racism and apartheid are singled out as scourges that have afflicted South Africans for over three-and-half centuries in respect of the first four scourge, and for four-and-half decades in respect of apartheid.� Against this backdrop, the struggles of the people of South Africa against these scourges are portrayed and analysed.� With the attainment of freedom and democracy in 1994, the� ANC led government enacted pieces of legislation whose aim was to deepen and broaden democracy, thereby transforming the society beyond recognition of how it was before 1994. Celebrating the first ten years of freedom and democracy, the people of South Africa are taking stock of what has been achieved and not achieved and bracing themselves for the challenges that are facing them into the second decade.

  17. Idaho National Laboratory Ten-Year Site Plan Project Description Document

    Energy Technology Data Exchange (ETDEWEB)

    Not Listed

    2012-03-01

    This document describes the currently active and proposed infrastructure projects listed in Appendix B of the Idaho National Laboratory 2013-2022 Ten Year Site Plan (DOE/ID-11449). It was produced in accordance with Contract Data Requirements List I.06. The projects delineated in this document support infrastructure needs at INL's Research and Education Campus, Materials and Fuels Complex, Advanced Test Reactor Complex and the greater site-wide area. The projects provide critical infrastructure needed to meet current and future INL opereational and research needs. Execution of these projects will restore, rebuild, and revitalize INL's physical infrastructure; enhance program execution, and make a significant contribution toward reducing complex-wide deferred maintenance.

  18. A Ten Year Analysis of Fatal Peripheral Vascular Injuries Autopsy Study

    Directory of Open Access Journals (Sweden)

    Salim Tuncer

    2016-04-01

    Full Text Available Aim: Peripheral vascular injuries are usually associated with fatal injuries. Early diagnosis and intervention are so vital for improving a favorable outcome for traumatic vascular injuries. As a preventable cause of death, we aimed to evaluate peripheral vascular injuries in overall deaths in ten year period, 2003-2012. Material and Method: A retrospective evaluation was made of 2845 death cases which had post-mortem examination and autopsy from the 10-year period of 2003-2012 in Eskisehir, Turkey. The mean age of the cases included in the study was 32.5±7.9 years with the highest rate of cases occurring in the 30-39 years age group. Males constituted 89.2% of the victims. The most frequent manner of death was homicide 83.8%.The femoral artery was the most commonly injured vessel 29 cases (78.4%. In this study it was identified that, 33 patients (89.3% died before any medical intervention could be performed. Discussion: Our study shows that, peripheral vascular injuries most commonly caused by sharp objects. The injuries have a low mortality rate when early intervention is made. Autopsies are conducted is very important to explain not only the cause of death but also the treatment process, which would clear the cases of any potential malpractice or negligence claims.

  19. [Ten years of human papilloma virus vaccination. From dermatology to oncology via the infectious diseases department].

    Science.gov (United States)

    Moraga-Llop, Fernando A

    2018-02-07

    Human papilloma virus (HPV) was first identified in dermatology, and it was subsequently demonstrated that is was required for the development of uterine cervical cancer and other tumours, after a persistent infection by any of its oncogenic genotypes. Ten years ago, the most common infections and cancers associated with HPV could be prevented by immunisation with 2vaccines, one bivalent, and another tetravalent, and having just marketed a nonavalent one. During the period 2007-2008, the HPV vaccine was included in the Autonomous Communities vaccination calendar, and it is the second vaccine, after that of Hepatitis B, that prevents cancer. In these 10 years that these vaccines have been available the knowledge has progressed and there have been significant advances in vaccination strategies, as well as in the indications and recommendations. These include, lowering the age in the vaccination schedule, prescribing of 2doses at 9 years and at 13-14 years, systematic vaccination of the male in some countries, immunisation of the woman after adolescence, implementation of vaccination programmes in developed countries, prevention of other cancers, recommendations for vaccinations for populations at high risk of HPV infection, scientific evidence on the impact and effectiveness of vaccination, and confirmation of the safety of these vaccines, with more than 270 million doses administered, as has already been observed in clinical trials. The role of health professionals is essential to achieve and maintain high vaccine coverage. Copyright © 2018. Publicado por Elsevier España, S.L.U.

  20. Green Tea as an Agricultural Based Health Promoting Food: The Past Five to Ten Years

    Directory of Open Access Journals (Sweden)

    Qin-Yin Shi

    2012-12-01

    Full Text Available The consumption of tea originated in ancient China over 4000 years ago and is currently the second most popular beverage in the world after water. Tea is an aromatic beverage prepared by pouring hot water over cured leaves of the Camellia sinensis plant. The link between tea intake, most notably green tea, and health has resulted in intense research on the components responsible for preventing the onset of several chronic diseases, including atherosclerosis, cancer, obesity and diabetes. In particular, the high levels of chemically diverse phenols (e.g., phenolic acids, flavonoids present in tea exhibit potent protective properties against many of these diseases. Although health related research on green tea and its predominant phenol (catechins has been on-going for decades, major advances have occurred in the last 5–10 years. Therefore, this review focuses on seminal studies reported primarily within the last five years but not extending past ten years on the link between health and green tea with an emphasis on the catechins.

  1. Medical School Attrition-Beyond the Statistics A Ten Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Maher Bridget M

    2013-01-01

    Full Text Available Abstract Background Medical school attrition is important - securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001–2011 and to study the personal effects of dropout on individual students. Methods The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. Results Overall attrition rate was 5.7% (45/779 in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR = 5.70, 95% Confidence Intervals 2.65 to 12.27;p  Absenteeism was documented in 30% of students, academic difficulty in 55.7%, social isolation in 20%, and psychological morbidity in 40% (higher than other studies. Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. Conclusions While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All

  2. Prognostic factors in children with acute lymphoblastic leukemia: a ten year study

    Directory of Open Access Journals (Sweden)

    Oloomi yazdi Z.

    2008-06-01

    Full Text Available Background: Acute lymphoblastic leukemia (ALL is the most common cancer in the pediatric population. With modern treatments, the chance of the complete recovery is nearly 100%. The most important prognostic factors are appropriate treatment protocol and determination of patient risk factors based on clinical, morphological, immunological and cytological characteristics. In this study we reviewed frequency of these factors, like as age, gender, the primary white blood cell number, sub- group on the base of FAB classification, immunophenotype and the clinical progress. Methods: In this retrospective study, we reviewed 877 pediatric patients with the diagnosis of ALL between the years of 1994 and 2004. In these patients the age, gender, primary WBC count, sub-group based on the FAB classification, immunophenotype and the clinical progress in 177 patient with acute lymphoblastic leukemia at Imam Khomeini Hospital between the years of 1994 to 2004 were determined. Results: Of these patients, 1.6% was younger than one year, 24.8% more than ten years old and 73.6% were between the ages of one and ten years; 63.8% were male. WBC counts were above 50,000/ul in 28.8% of the patients. FAB classifications included L1 in 80.2%, L2 in 17.5% and L3 in 2.3% of the patients. Immunophenotypes included pre-B cell in 63.8%, early pre-B cell in 23.1%, T cell in 12.3% and mature B cell in 0.8% of the patients. Marker CD10+ was detected in 88.1% of the B cell cases. In this study group, 74% of the patients recovered, 16.3% died and 16.5% relapsed.Conclusions: The prevalence of FAB-L1 and pre-B cell cases in this study is greater than a previous study, while the prevalence of FAB-L2 and early pre-B cell cases is less than that of the previous study.

  3. A ten-year study of depressive symptoms in Serbian medical students.

    Science.gov (United States)

    Ristić-Ignjatović, Dragana; Hinić, Darko; Jakovljević, Mihajlo; Fountoulakis, Kostas; Siepera, Marianna; Rancić, Nemanja

    2013-06-01

    The main objective of this study was to examine the rate of three dimensions of depressive symptoms in medical student population in Serbia, and to find out whether this rate had changed over the period often years. This cross-sectional study included 615 medical students (F = 61% and M = 39%), mean age = 23.60 (SD = 1.541), who were tested in five non-consecutive surveys between 2002 and 2012. Depressive symptoms were measured by the Beck Depression Inventory (BDI). The mean BDI score for the entire sample was 6.26 +/- 6.175. There was no significant difference in total BDI score among the values obtained during the ten years of testing. The greatest portion of the examined sample (77.24%) had no signs of depressive symptoms, and there was no difference in symptom intensity between medical students and other educational profiles. Similar to previous results, females had higher scores on all depressive dimensions except for one tested year, whereas a weak correlation was found between BDI scores and student age (r = 0.104; p = 0.010). Since there are still discrepancies among studies that do (not) report that medical students have typical depressive symptoms, potential explanations for the mentioned discrepancies may be found in individual characteristics of the members of the student population. Our suggestions for future studies are that they should include the stress factor, stress coping strategies, estimated life satisfaction, and the impact of these factors on the potential mental disorders.

  4. Management of orbital cellulitis and subperiosteal orbital abscess in pediatric patients: A ten-year review.

    Science.gov (United States)

    Sciarretta, Vittorio; Demattè, Marco; Farneti, Paolo; Fornaciari, Martina; Corsini, Ilaria; Piccin, Ottavio; Saggese, Domenico; Fernandez, Ignacio Javier

    2017-05-01

    Pediatric periorbital cellulitis represents a common disease complicating a nasal infection. A ten-year retrospective review of fifty-seven children admitted to our institution with the diagnosis of periorbital cellulitis as a complication of sinus infections was carried out. The age varied from one month to eleven years (mean 3.9 years). Thirty-five were males (62%), while twenty-two were females (38%). Nine out of fifty-seven (15.8%) presented exophthalmos associated with eyelid erythema and edema, while the rest suffered mainly from eyelid erythema and edema. Twenty-two patients complaining of exophthalmos or not responding to medical therapy within 48 h were assessed with a computed tomography scan (38.6%). A subperiosteal orbital abscess was detected in nine cases and these patients underwent surgical drainage (15,8%). Recurrence of orbital infection occurred in three cases (5.3%). Medical management is the main treatment for both preseptal and postseptal orbital cellulitis. Nevertheless, there is no universally accepted guideline for the treatment of subperiosteal abscesses and each case should be treated accordingly. Urgent surgical drainage should be considered in cases not responding to adequate medical management, or those cases presenting visual deterioration. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Ten Years On, the Kimberley Process Certification Scheme and Zimbabwe's Marange and "Conflict Diamonds": Lessons to be learnt

    OpenAIRE

    Nazreen Shaik-Peremanov

    2014-01-01

    TEN YEARS ON, THE KIMBERLEY PROCESS CERTIFICATION SCHEME AND ZIMBABWE’S MARANGE AND "CONFLICT DIAMONDS": LESSONS TO BE LEARNT N Shaik-Peremanov* SUMMARY Remove by editor - Prof Christa Rautenbach email:

  6. More than skin deep. Ten year follow-up of delayed cutaneous adverse drug reactions (CADR).

    Science.gov (United States)

    Graudins, Linda Velta; Ly, Jenny; Trubiano, Jason; Aung, Ar Kar

    2016-10-01

    To determine the gaps in practice regarding appropriate ADR documentation and risk communication for patients diagnosed with severe cutaneous adverse drug reactions (CADR). This was a retrospective observational cohort study conducted using hospital coding and databases to identify inpatients diagnosed with CADR from January 2004 to August 2014. Hospital discharge summaries, ADR reports and pharmacy dispensing records were reviewed for ADR documentation. Patients still living in Australia and who did not opt out of being contacted were invited to be surveyed by telephone to determine their understanding of recommendations, re-exposure rates and long-term effects. Of 85 patients identified, median age was 59 (IQR 44-72) years and 47.1% were male. The most common diagnosis was TENS (49.4%). Ten patients (11.8%) died as inpatients. Of the 81 patients with a drug-related causality, 47 (58%) had appropriate documentation in all three required medical record platforms. Of the 56 eligible patients, 38 (67.9%) were surveyed; 13% had no information provided upon discharge and 26.3% patients had a mismatch in knowledge of implicated medications. No surveyed patient had a relapse of CADR, but 23.7% had a subsequent unrelated allergic reaction. Thirteen patients (34.2%) reported long-term effects. We found gaps in the accuracy of ADR documentation and communication of risk at discharge, which indicated risks to patient safety. Electronic systems are being developed to improve documentation. Written information about CADR is being provided at discharge to improve patient understanding and knowledge. © 2016 The British Pharmacological Society.

  7. Eventos adversos associados à exsanguíneotransfusão na doença hemolítica perinatal: experiência de dez anos Adverse events related to exchange transfusion in newborn infants with hemolytic disease: ten years of experience

    Directory of Open Access Journals (Sweden)

    Cynthia Amaral M. Sá

    2009-06-01

    Full Text Available OBJETIVO:Determinar a incidência dos eventos adversos atribuíveis à exsanguíneotransfusão ocorridos em uma Unidade de Terapia Intensiva Neonatal (UTIN e sua associação com a gravidade clínica do paciente. MÉTODOS: Foram incluídos no estudo todos os recém-nascidos internados com diagnóstico de doença hemolítica perinatal por aloimunização Rh em uma unidade neonatal no período de dez anos. Os pacientes foram separados em dois grupos de acordo com o quadro clínico anterior à exsanguíneotransfusão e calculou-se o risco relativo para cada evento adverso entre os grupos. RESULTADOS: 300 recém-nascidos foram internados com diagnóstico de anemia hemolítica por aloimunização Rh durante o período do estudo. Desses, 143 foram submetidos a 207 exsanguíneotransfusões, sendo que 93 (65% realizaram apenas um procedimento. A principal indicação da exsanguíneotransfusão foi a velocidade de hemólise (57%. A incidência de eventos adversos foi 22,7% e a mortalidade associada ao procedimento ocorreu em 0,7% dos pacientes. Os eventos adversos, em sua maioria, foram assintomáticos e o mais comum foi a plaquetopenia. Os pacientes do Grupo 2, que apresentarem icterícia associada a outros agravos clínicos antes do procedimento, tiveram um risco 2,1 vezes maior de apresentar eventos adversos graves (RR: 2,1; IC 95%: 1,3-3,4. Houve apenas um óbito relacionado ao procedimento no período. CONCLUSÕES: Apesar de a exsanguíneotransfusão ser um procedimento frequentemente utilizado em casos de hiperbilirrubinemia grave, é alta a incidência de eventos adversos a ela relacionada, principalmente se a condição clínica do paciente for instável antes do procedimento.OBJECTIVE:To determine the incidence of adverse events associated with exchange-transfusions performed during the past ten years and to evaluate if there is association between the severity of patient's clinical condition before the procedure and the incidence of adverse

  8. Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU

    Science.gov (United States)

    Slater, T. F.; Slater, S. J.

    2013-12-01

    For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational

  9. A Vision for the Next Ten Years for Integrated Ocean Observing Data

    Science.gov (United States)

    Willis, Z. S.

    2012-12-01

    Ocean observing has come a long way since the Ocean Sciences Decadal Committee met over a decade ago. Since then, our use of the ocean and coast and their vast resources has increased substantially - with increased shipping, fishing, offshore energy development and recreational boating. That increased use has also spearheaded advances in observing systems. Cutting-edge autonomous and remotely operated vehicles scour the surface and travel to depths collecting essential biogeochemical data for better managing our marine resources. Satellites enable the global mapping of practically every physical ocean variable imaginable. A nationally-integrated coastal network of high-frequency radars lines the borders of the U.S. feeding critical navigation, response, and environmental information continuously. Federal, academic, and industry communities have joined in unique partnerships at regional, national, and global levels to address common challenges to monitoring our ocean. The 2002 Workshop, Building Consensus: Toward an Integrated and Sustained Ocean Observing System laid the framework for the current United States Integrated Ocean Observing System (U.S. IOOS). Ten years later, U.S. IOOS has moved from concept to reality, though much work remains to meet the nation's ocean observing needs. Today, new research and technologies, evolving users and user requirements, economic and funding challenges, and diverse institutional mandates all influence the future growth and implementation of U.S. IOOS. In light of this new environment, the Interagency Ocean Observation Committee (IOOC) will host the 2012 Integrated Ocean Observing System Summit in November 2012, providing a forum to develop a comprehensive ocean observing vision for the next decade, utilizing the knowledge and expertise gained by the IOOS-wide community over the past ten years. This effort to bring together ocean observing stakeholders at the regional, national, and global levels to address these challenges

  10. Ten Years of Using Presentations at a Student Conference as a Final Assessment

    Science.gov (United States)

    Lund, Nick

    2013-01-01

    The final assessment for all psychology courses in the department of interdisciplinary studies, MMU Cheshire programmes, in the past 10 years has been a presentation of project work at an undergraduate conference. It is argued that this acts as an "authentic" assessment method which helps prepare students for future experiences. Alumni…

  11. Highlighting ten years of physics education research in the upper division

    Science.gov (United States)

    Ambrose, Bradley

    2015-04-01

    The field of Physics Education Research (PER) has for over thirty years provided insights into student thinking and guided the development and assessment of reformed teaching strategies and practices in introductory physics courses. In the last decade or so, researchers have expanded the domain of such investigations to upper-division courses where undergraduate majors study more advanced content and begin to see themselves as future physicists. The upcoming Focused Collection on Upper Division PER brings together work from researchers active in these new frontiers of PER. In this presentation we provide an overview of the studies in this collection, which offer to the PER and greater physics education communities: new insights about the thinking, behavior, and beliefs of students in the upper division; new tools to innovate instruction, assess student learning, and evaluate teaching effectiveness; and groundbreaking studies of identity development and ``thinking like a physicist'' among physics majors. In this session we also recognize the ten-year anniversary of Physical Review Special Topics: Physics Education Research, an occasion that we will celebrate with an informal reception immediately following the conclusion of this invited session.

  12. Scientometric analysis of published papers in global ophthalmology in the past ten years.

    Science.gov (United States)

    Yu, Zheng-Lu; Hu, Xin-Yue; Wang, Ying-Na; Ma, Zheng

    2017-01-01

    To investigate the published papers of ophthalmology in past ten years and explore the development of ophthalmology. The data of this study retrieved from Science Citation Index Expanded and downloaded online in November 2017, including all the papers with publication year from 2007-2016 were analyzed. The papers were based on the Web of Science category and the journals were based on the Journal Citation Report category. The number of ophthalmology papers increased from 7450 to 9089 during 2007 to 2017. The average rate increased 2.2% annually. USA accounts for one thirds of the total and two thirds of the highly cited papers. In Asia, China, Japan and South Korea were in Top 10 by the number of ophthalmology papers. UK, Germany, Japan and Australia also had great impact in global ophthalmology. The hot spots included endothelial growth factor, optical coherence tomography and open-angle glaucoma. USA is in the leading position in global ophthalmology. Part of Asian countries play an important role in the development of ophthalmology, but the impact needs to be improved.

  13. Ten-year rank-order stability of personality traits and disorders in a clinical sample.

    Science.gov (United States)

    Hopwood, Christopher J; Morey, Leslie C; Donnellan, M Brent; Samuel, Douglas B; Grilo, Carlos M; McGlashan, Thomas H; Shea, M Tracie; Zanarini, Mary C; Gunderson, John G; Skodol, Andrew E

    2013-06-01

    This study compares the 10-year retest stability of normal traits, pathological traits, and personality disorder dimensions in a clinical sample. Ten-year rank-order stability estimates for the Revised NEO Personality Inventory, Schedule for Nonadaptive and Adaptive Personality, and Diagnostic Interview for DSM-IV Personality Disorders were evaluated before and after correcting for test-retest dependability and internal consistency in a clinical sample (N = 266). Dependability-corrected stability estimates were generally in the range of.60-.90 for traits and.25-.65 for personality disorders. The relatively lower stability of personality disorder symptoms may indicate important differences between pathological behaviors and relatively more stable self-attributed traits and imply that a full understanding of personality and personality pathology needs to take both traits and symptoms into account. The five-factor theory distinction between basic tendencies and characteristic adaptations provides a theoretical framework for the separation of traits and disorders in terms of stability in which traits reflect basic tendencies that are stable and pervasive across situations, whereas personality disorder symptoms reflect characteristic maladaptations that are a function of both basic tendencies and environmental dynamics. © 2012 Wiley Periodicals, Inc.

  14. Naive (commonsense) geography and geobrowser usability after ten years of Google Earth

    Science.gov (United States)

    Hamerlinck, J. D.

    2016-04-01

    In 1995, the concept of ‘naive geography’ was formally introduced as an area of cognitive geographic information science representing ‘the body of knowledge that people have about the surrounding geographic world’ and reflecting ‘the way people think and reason about geographic space and time, both consciously and subconsciously’. The need to incorporate such commonsense knowledge and reasoning into design of geospatial technologies was identified but faced challenges in formalizing these relationships and processes in software implementation. Ten years later, the Google Earth geobrowser was released, marking the beginning of a new era of open access to, and application of, geographic data and information in society. Fast-forward to today, and the opportunity presents itself to take stock of twenty years of naive geography and a decade of the ubiquitous virtual globe. This paper introduces an ongoing research effort to explore the integration of naive (or commonsense) geography concepts in the Google Earth geobrowser virtual globe and their possible impact on Google Earth's usability, utility, and usefulness. A multi-phase methodology is described, combining usability reviews and usability testing with use-case scenarios involving the U.S.-Canadian Yellowstone to Yukon Initiative. Initial progress on a usability review combining cognitive walkthroughs and heuristics evaluation is presented.

  15. Prevalence of oral squamous cell carcinoma cases for ten years in Qazvin province (2003-13

    Directory of Open Access Journals (Sweden)

    F. Keshani

    2017-06-01

    Full Text Available Background: Human cancers comprise a large group of diseases that despite modern methods of diagnosis and advanced treatment techniques its mortality rate is high. Considering the role of environmental and cultural factors in the prevalence of oral cancer, epidemiological studies have a great importance. Objective: The aim of this research was to determine the prevalence of oral squamous cell carcinoma (OSCC in the province of Qazvin in a period of ten years. Methods: In this descriptive - analytical study, the documents of 88 patients with OSCC that were recorded by the Qazvin Cancer Registry Center during 2003-13, were used. Demographic data including age, sex and location of lesions were extracted from patient records. Data analysis were performed using chi-square, t-test and fisher exact test. Findings: Among the 88 patients, the average age was 64.3±17.7. The male to female ratio was 1 to 1.37 and the most involved area was tongue with 39 cases (63.9%, and the lowest was upper lip with 1 case (1.6%. The most of the patients were in the age between 70-80 years old. Conclusions: Pattern of OSCC in this study was similar to the other studies but the number of females and the mean age of patient had increased. Also, the mean age of patients was increased in eight decades and the most involved area tongue was reported.

  16. Epidemiology, management and survival outcomes of primary cutaneous melanoma: a ten-year overview.

    Science.gov (United States)

    Aubuchon, M M F; Bolt, L J J; Janssen-Heijnen, M L G; Verleisdonk-Bolhaar, S T H P; van Marion, A; van Berlo, C L H

    2017-02-01

    Malignant melanoma (MM) is the most aggressive type of skin cancer, accounting for 90% of all the skin cancer mortality. The objective of this study was providing an overview of current patient- and tumour characteristics, treatment strategies, complications and survival in patients with MM over the past ten years. Hereby, an up-to-date view of every day clinical practice is obtained. Files of patients treated for primary cutaneous melanoma (n = 686) in the VieCuri Medical Centre in the Netherlands between January 2002 and December 2013 were retrospectively reviewed. Relevant patient features, tumour characteristics, and (surgical) outcomes were evaluated. The majority of all the patients presented thin tumours (59.1% stage 1A/in situ melanoma). Men showed more ulceration (17.7% vs. 8.4%, p < .01) and a significantly higher Breslow thickness than women (1.2 mm vs. 0.9 mm, p < .01). 14.6% (40/273) underwent sentinel lymph node biopsy (SLNB); 10/40 (25%) showed nodal metastasis, 50 patients (7.3%) developed distant metastases (M: 10.6%, F: 5%, p < .01). One-, 5- and 10- year disease specific survival rates were 96%, 86% and 84%, respectively. Median survival for stage 4 MM was 3 months. Extensive surgery was uncommon (n = 3). Patients generally presented with thin melanomas. Lymph node disease and distant metastases remained infrequently observed during following years, and general 1- and 5-year overall disease-specific survival rates exceeded 85%. Small numbers of rescue surgery and palliative medical treatment warrant further centralisation and investigation.

  17. Ten years of RELEA: achievements and challenges for astronomy education development

    Science.gov (United States)

    Bretones, Paulo Sergio; Jafelice, Luiz Carlos; Horvath, Jorge Ernesto

    2015-08-01

    When an area of education, and more particularly the research within this area, is aimed to development, a basic requirement is the existence of a regular publication that accounts for the scientific production in that area. This study aims to analyze 10 years of Latin-American Journal of Astronomy Education (RELEA). Publishing policies of the RELEA and their context are discussed in relation to submission, refereeing and publication. The 75 articles published in 18 editions are analyzed and classified by: year of publication, edition, the authors' institutions, school level, study focus and content. The results present trends and shortcomings of the production. A comparison with the number of articles published in other Brazilian journals of education and an analysis of the international scene in relation to other type publications along these ten years is made. Given that this journal is now consolidated, its future prospects in the international landscape are further considered. The challenges related to article submission are discussed: how to increase their number, the submission of Latin American countries, and how to bring in the issues and subjects not addressed until now. It is also considered the possibility of encouraging graduate studies, new lines of research in astronomy education, and dissemination of material in schools and universities for teachers and students. Finally, future possibilities are discussed given the IAU development programs. For example, more article submission from Portuguese-speaking countries with the support of Regional Nodes and Language Expertise Centers, and opportunities for volunteer IAU members and global projects for the development of astronomy education.

  18. Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

    DEFF Research Database (Denmark)

    Simonsen, Erik; ten Velden Hegelstad, Wenche; Haahr, Ulrik Helt

    2013-01-01

    years, 50% of patients were in symptomatic remission. Non-remission was predicted by positive symptoms at inclusion and during the first year of treatment. Of individual symptoms only hallucinations were significantly predictive of ten-year non-remission. Early symptom differences were not reflected...

  19. Organisation and Management of a Complete Bachelor Degree Offered Online at the University of Milan for Ten Years

    Science.gov (United States)

    Milani, Manuela; Papini, Sabrina; Scaccia, Daniela; Scarabottolo, Nello

    2014-01-01

    This paper is aimed at presenting some reflections on organisation and management of SSRI online: an e-learning initiative started at the University of Milan (Italy) in the academic year 2004/05 and offered to students over the last ten years. The initiative consisted in implementing the online version of an already existing three-year bachelor…

  20. Infecção por Chlamydia trachomatis no período neonatal: aspectos clínicos e laboratoriais. Experiência de uma década: 1987-1998 Chlamydia trachomatis infection in neonatal period. Clinical and Laboratorial aspects. Experience of ten years: 1987-1998

    Directory of Open Access Journals (Sweden)

    F.A.C. Vaz

    1999-12-01

    sorológico se mostraram importantes como métodos auxiliares do diagnóstico.Chlamydia trachomatis infection is adquired by the newborn infant during the delivery, 25 to 50 % of them may develop conjunctivitis and 10 to 20 % pneumonia. BACKGROUND: To verify the incidence of ocular infection by C. trachomatis in the newborn infants with conjunctivitis. To observe the association between ocular infection and intersticial pneumonia.-Study the epidemiological aspects and laboratorial methods of criterial diagnosis. CASUISTICS AND METHODS: We studied the newborn infants admitted in the intensive neonatal care with diagnostic of conjunctivitis and/or interstitial pneumonia during the period of ten years. The diagnostic methods were direct exam of etiologic agent in conjunctival material, X ray chest and serologic test by imunofluorescence method for IgG and IgM antibodies. RESULTS: We studied the clinical characteristics of 20 newborns infants with chlamydial trachomatis infection: 15 (75% were terms newborns and 5 (25% pre-terms. We observed the predominance of infection in females (60%; pneumonia was observed in 15/20 (75% and 12 of them had both: conjunctivitis and pneumonia. we did not observe significant association among type of delivery, age of the mother, number of partner and infection. Leukorrhea was present em 50% of the mothers The serologic test was positive in 100% of the newborn with pneumonia and none with conjunctivitis alone,and the direct exam in conjuntival material was positive in newborns with conjunctivitis. The incidence of C. trachomatis in the newborns admitted in this period with conjunctivitis were 17/100 (17%. CONCLUSION: Chlamydia trachomatis is an important pathogenical agent and the research of it is essential in newborn infants with conjunctivitis and/or interstitial pneumonia even there were not risk factors for sexually transmitted diseases. The direct exam of conjunctival material and serologic test are very important to diagnosis.

  1. Transplante alogênico de células-tronco hematopoéticas em leucemias agudas: a experiência de dez anos do Hospital das Clínicas da UFMG Allogeneic hematopoietic stem cells transplantation in acute leukemia: ten years of experience in the Hospital das Clínicas - UFMG

    Directory of Open Access Journals (Sweden)

    Rosana M. Lamego

    2010-01-01

    Full Text Available As leucemias agudas são doenças com alta morbimortalidade para as quais o transplante alogênico de medula óssea é uma opção terapêutica eficaz. Neste artigo, relatamos a experiência de um centro brasileiro com pacientes apresentando leucemia aguda que receberam um enxerto de medula óssea ou células-tronco periféricas de um doador familiar HLA idêntico no período de julho de 1995 a dezembro de 2005. Foi realizado um estudo de coorte retrospectivo, analisando dados de 125 pacientes com mediana de idade de 28,7 anos. Oitenta e um pacientes (64,8% apresentavam leucemia mieloide aguda; 38 (30,4%, leucemia linfoide aguda; e seis (4,8%, leucemia bifenotípica. Trinta e dois pacientes encontravam-se em primeira remissão completa, 23 em segunda remissão e 70 com doença avançada (refratários, recidivados ou além da segunda remissão. A sobrevida global estimada em 10 anos foi de 22,9%. Em relação à situação clínica do paciente no momento do transplante, a sobrevida global em dez anos foi de 56,3% para pacientes em primeira remissão, 38% para os pacientes em segunda remissão, e 3,7% para os pacientes com doença avançada. Considerando-se os pacientes transplantados em primeira e segunda remissão, a evolução foi semelhante aos dados disponíveis na literatura. Entretanto, os resultados dos pacientes transplantados em fase avançada foram ruins, devendo-se discutir o papel do transplante para este grupo.Acute leukemias are a group of diseases with high morbimortality. Allogeneic bone marrow transplantation is an efficacious therapeutic option for their treatment. We report the experience of a Brazilian center in respect to acute leukemia patients who received a bone marrow or peripheral blood allograft from a HLA-matched sibling from July 1995 to December 2005. Data were retrospectively collected. The median age of the 125 patients included in the study was 28.7 years. Eighty-one patients presented with acute myeloid leukemia

  2. Ten years of iPSC: clinical potential and advances in vitro hematopoietic differentiation.

    Science.gov (United States)

    Paes, Bárbara Cristina Martins Fernandes; Moço, Pablo Diego; Pereira, Cristiano Gonçalves; Porto, Geciane Silveira; de Sousa Russo, Elisa Maria; Reis, Luiza Cunha Junqueira; Covas, Dimas Tadeu; Picanço-Castro, Virginia

    2017-06-01

    Ten years have passed since the first publication announcing the generation of induced pluripotent stem cells (iPSCs). Issues related to ethics, immune rejection, and cell availability seemed to be solved following this breakthrough. The development of iPSC technology allows advances in in vitro cell differentiation for cell therapy purpose and other clinical applications. This review provides a perspective on the iPSC potential for cell therapies, particularly for hematological applications. We discuss the advances in in vitro hematopoietic differentiation, the possibilities to employ iPSC in hematology studies, and their potential clinical application in hematologic diseases. The generation of red blood cells and functional T cells and the genome editing technology applied to mutation correction are also covered. We highlight some of the requirements and obstacles to be overcome before translating these cells from research to the clinic, for instance, iPSC variability, genotoxicity, the differentiation process, and engraftment. Also, we evaluate the patent landscape and compile the clinical trials in the field of pluripotent stem cells. Currently, we know much more about iPSC than in 2006, but there are still challenges that must be solved. A greater understanding of molecular mechanisms underlying the generation of hematopoietic stem cells is necessary to produce suitable and transplantable hematopoietic stem progenitor cells from iPSC.

  3. Ten years of ozone research at DLR; Ergebnisse aus zehn Jahren Ozonforschung im DLR

    Energy Technology Data Exchange (ETDEWEB)

    Dameris, M.; Schumann, U. [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Wessling (Germany). Inst. fuer Physik der Atmosphaere

    2000-02-01

    After ten years of ozone research, depletion of stratospheric ozone over the Antarctic and Arctic regions and also over Europe is still not fully understood although its progress can be predicted by models. The state of the art was presented in the report 'Scientific Assessment of Ozone Depletion: 1998' of the World Meteorological Organisation. There is also a national documentation '10 Jahre Deutsche Ozonforschung 1989 bis 1999', to which DLR scientists made significant contributions. Some of their projects and findings are presented here. Research will be stimulated by the 2001 start of the ENVISAT satellite of the ESA. [German] Nach zehn Jahren Ozonforschung ist die Abnahme der Ozonschicht in der Stratosphaere nicht nur ueber der Antarktis (Ozonloch), sondern auch ueber der Arktis und Europa ein Faktum, das man heute weitgehend, wenn auch immer noch nicht vollstaendig versteht und dessen weitere Entwicklung man mit Modellen berechnen kann. Der Stand des Wissens wurde in einem umfassenden Bericht 'Scientific Assessment of Ozone Depletion: 1998' unter Federfuehrung der World Meteorological Organisation zusammengestellt. National gibt es eine Dokumentation '10 Jahre Deutsche Ozonforschung 1989 bis 1999'. Wissenschaftler des DLR haben zu den Erkenntnissen mit zahlreichen Publikationen wesentlich beigetragen. Einige der Projekte und Ergebnisse werden hier vorgestellt. Mit dem fuer 2001 geplanten Start des Umweltsatelliten ENVISAT der ESA erhaelt das Thema neue Aktualitaet. (orig.)

  4. Modeling the Office of Science Ten Year Facilities Plan: The PERI Architecture Tiger Team

    Energy Technology Data Exchange (ETDEWEB)

    de Supinski, Bronis R.; Alam, Sadaf; Bailey, David H.; Carrington, Laura; Daley, Chris; Dubey, Anshu; Gamblin, Todd; Gunter, Dan; Hovland, Paul D.; Jagode, Heike; Karavanic, Karen; Marin, Gabriel; Mellor-Crummey, John; Moore, Shirley; Norris, Boyana; Oliker, Leonid; Olschanowsky, Catherine; Roth, Philip C.; Schulz, Martin; Shende, Sameer; Snavely, Allan; Spear, Wyatt; Tikir, Mustafa; Vetter, Jeff; Worley, Pat; Wright, Nicholas

    2009-06-26

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort optimizing key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfill our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  5. [The ten-year retrospect of nutrition and health status of pregnant women in China].

    Science.gov (United States)

    Dong, C X; Yin, S A

    2018-01-06

    Improvement of the nutrition and health status of pregnant women should be one of the top priority strategies of improving the physical fitness of next generation and reserve of talented person for national sustainable development. This paper reviews the nutrition and health status of pregnant women in China over the recent ten years and discusses the underlying factors and changing trends. The most popular nutrition-related problem is dietary imbalance, and many micronutrient intakes are lower than the recommended dietary intakes or adequate intakes, and some of nutrient intakes are still at a very low level for a long time such as vitamin D and calcium. The nutrition-related health problems are mainly anemia, vitamin D and vitamin A deficiencies; iodine intake is not in optimal state with a large proportion of inadequate and individual cases facing excessive intake risk. Overweight and obesity, pregnancy complications such as gastrocnemius muscle spasms, pregnancy hypertensive disorders and gestational diabetes were prevalent among pregnant women. We should address both malnutrition and nutrition imbalance in the same time in order to improve the nutrition and health status of pregnant women, by developing and implementing relevant laws and regulations, giving higher attention to pregnant women with advanced age, which in turns prevent a variety of micronutrient deficiencies, reduce adverse pregnant outcomes, and improve nutrition and health status of maternal and child.

  6. Ten years after "Worrying trends in econophysics": developments and current challenges

    Science.gov (United States)

    Ormerod, Paul

    2016-12-01

    Econophysics has made a number of important additions to scientific knowledge. Yet it continues to lack influence with both economists and policy makers. Ten years ago, I and three other economists sympathetic to econophysics wrote a paper on worrying trends within the discipline. For example, its lack of awareness of the economics literature, and shortfalls in the use of statistical analysis. These continue to be obstacles to wider acceptance by economists. Like all agents, policy makers respond to incentives, and economists understand this very well. Much of the econophysics community appears to think that simply doing good science is sufficient to have the work recognised, rather than relating to the motivations and incentives of policy makers. Nevertheless, econophysics now has three major opportunities to advance knowledge in areas where policy makers perceive weaknesses in what they are presented with by economists. All can benefit from the analysis of Big Data. The first is a core model of agent behaviour which is more relevant to cyber society than the rational agent model of economics. Second, extending our understanding of the business cycle, primarily by incorporating the importance of networks into models. Third, devising proper measures of output in cyber society.

  7. [Thinking about academic development of acupuncture and moxibustion in recent ten years].

    Science.gov (United States)

    Wen, Bi-ling; Jia, Chun-sheng; Liu, Wei-hong; Yang, Yong-qing; Wang, Ling-ling; Yang, Hua-yuan; Wu, Xiao-dong; Shen, Xue-yong; Xu, Ping; Zhao, Jing-shen; Liu, Jun-ling; Cheng, Kai; Zhu, Wen-zeng

    2009-12-01

    Through combing the academic development of acupuncture in recent ten years, objectively reflects the real development status of acupuncture subject on these aspects sucl as basis, clinic, equipment, teaching and standardization, etc., shows the scientific and technological achievements and the highlights of the acupuncture academic development, analyzes the bottleneck and dilemma of the acupuncture academic development. It is indicated that there are several problems existed in acupuncture researche at present, such as the scale and the input of the acupuncture theory research are not enough, the basic research and clinical application is disjointed, the correlation between the acupoints and viscera need more systematic and further researches, the design level of clinical research on acupoints' main indications should be improved. From now on we should follow the inherent rule of the traditional theory of Chinese medicine and the way of integrated thinking, explore the new rule of acupuncture academic development, in order to fit the new historical period, and comprehensively promote the sustainable and coordinated development of acupuncture science.

  8. Ten-year operational dust forecasting - Recent model development and future plans

    Energy Technology Data Exchange (ETDEWEB)

    Kallos, G; Spyrou, C; Astitha, M; Mitsakou, C; Solomos, S; Kushta, J; Pytharoulis, I; Katsafados, P; Mavromatidis, E; Papantoniou, N; Vlastou, G [University of Athens, School of Physics, Atmospheric Modeling and Weather Forecasting Group - UOA/AM and WFG, University Campus, Bldg. PHYS-V, Athens 15784 (Greece)], E-mail: kallos@mg.uoa.gr

    2009-03-01

    The Sahara desert is one of the major sources of mineral dust on Earth, producing up to 2x10{sup 8} t yr-{sup 1}. A combined effort has been devoted during the last ten years at the University of Athens (UOA) from the Atmospheric Modeling and Weather Forecasting Group (AM and WFG) to the development of an analysis and forecasting tool that will provide early warning of Saharan dust outbreaks. The developed tool is the SKIRON limited-area forecasting system, based on the Eta limited area modeling system with embedded algorithms describing the dust cycle. A new version of the model is currently available, with extra features like eight-size particle bins, radiative transfer corrections, new dust source identification and utilization of rocky soil characterization and incorporation of more accurate deposition schemes. The new version of SKIRON modeling system is coupled with the photochemical model CAMx in order to study processes like the shading effect of dust particles on photochemical processes and the production of second and third generation of aerosols. Moreover, another new development in the AM and WFG is based on the RAMS model, with the incorporation of processes like dust and sea-salt production, gas and aqueous phase chemistry and particle formation. In this study, the major characteristics of the developed (and under development) modeling systems are presented, as well as the spatiotemporal distribution of the transported dust amounts, the interaction with anthropogenically-produced particles and the potential implications on radiative transfer.

  9. Dinosaurs in decline tens of millions of years before their final extinction

    Science.gov (United States)

    Sakamoto, Manabu; Benton, Michael J.

    2016-05-01

    Whether dinosaurs were in a long-term decline or whether they were reigning strong right up to their final disappearance at the Cretaceous-Paleogene (K-Pg) mass extinction event 66 Mya has been debated for decades with no clear resolution. The dispute has continued unresolved because of a lack of statistical rigor and appropriate evolutionary framework. Here, for the first time to our knowledge, we apply a Bayesian phylogenetic approach to model the evolutionary dynamics of speciation and extinction through time in Mesozoic dinosaurs, properly taking account of previously ignored statistical violations. We find overwhelming support for a long-term decline across all dinosaurs and within all three dinosaurian subclades (Ornithischia, Sauropodomorpha, and Theropoda), where speciation rate slowed down through time and was ultimately exceeded by extinction rate tens of millions of years before the K-Pg boundary. The only exceptions to this general pattern are the morphologically specialized herbivores, the Hadrosauriformes and Ceratopsidae, which show rapid species proliferations throughout the Late Cretaceous instead. Our results highlight that, despite some heterogeneity in speciation dynamics, dinosaurs showed a marked reduction in their ability to replace extinct species with new ones, making them vulnerable to extinction and unable to respond quickly to and recover from the final catastrophic event.

  10. Review suggests high survival rates for veneers at five and ten years.

    Science.gov (United States)

    Watt, Eileen; Conway, David I

    2013-03-01

    The Cochrane Library, Medline, Embase, and Web of Knowledge databases were searched and the Evidence-Based Dentistry, International Journal of Prosthodontics, Journal of Prosthetic Dentistry, Journal of Adhesive Dentistry, Journal of Esthetic and Restorative Dentistry, and Journal of Oral Rehabilitation were hand searched. Clinical trials registers, conference proceedings and academic colleagues were contacted to identify unpublished data, abstracts and other gray literature. There were no language limits. Article identification, screening, and eligibility and inclusion assessments were completed independently by two reviewers. Prospective and retrospective cohort and controlled trials assessing the outcome of feldspathic porcelain veneers in more than 15 patients were included. Some veneers in each study had to be in situ for five years. Veneers placed using unusual techniques, such as with no enamel preparation or excessive incisal edge lengthening, were excluded. Estimated cumulative survival and standard error for each study were assessed and used for meta-, sensitivity and post hoc analyses. The I(2) statistic and the Cochran Q test and its associated P value were used to evaluate statistical heterogeneity, with a random-effects meta-analysis used when the P value for heterogeneity was less than 0.1. Heterogeneity, publication patterns and small study biases were explored. Eleven studies were included with six (four prospective and two retrospective cohorts) contributing to the meta-analysis. The estimated cumulative survival for feldspathic porcelain veneers was 95.7% (95% confidence interval [CI]: 92.9% to 98.4%) at five years and ranged from 64% to 95% at ten years across three studies. A post hoc meta-analysis indicated that the 10-year best estimate may approach 95.6% (95% CI: 93.8% to 97.5%). High levels of statistical heterogeneity were found. When bonded to enamel substrate, feldspathic porcelain veneers have a very high 10-year survival rate that may

  11. Food items in the food intake of children aged seven to ten years.

    Science.gov (United States)

    Hinnig, Patrícia de Fragas; Hinnigi, Patrícia de Fragas; Bergamaschi, Denise Pimentel; Bergamaschi, Denise Pimental

    2012-06-01

    To describe the most representative food items regarding the total intake of energy, carbohydrates, proteins and lipids in children with ages between 7 and 10 years. A list was prepared with all food intake and quantities, and the diet composition in relation to energy and macronutrients was calculated. The list was based on information provided by a 3-day-Food Diary completed by 85 schoolchildren ranging from seven to ten years old and enrolled in a public school in São Paulo, Brazil. After dividing the food into 129 items, we calculated the percentage in which each item contributed to diet nutrient intake and identified those which contributed to up to 95% of the total intake of calories and selected nutrients. The items "White rice, Greek rice, rice with vegetables" and "Brown, black and white beans, lentils" contributed significantly to the total intake of energy and carbohydrates. The item "Whole milk, powdered milk" had a significant participation in the total intake of lipids, protein and energy. We emphasize the importance of carbohydrates and energy intake from sugar-sweetened beverages (sodas and processed juices) in the total diet intake of the children. the contribution of rice in the total food intake of energy and carbohydrates; of beans in energy, carbohydrates and proteins; of milk and meat in energy, protein and lipids; and bread in energy and carbohydrates is noticeable. The participation of sugar-sweetened beverage in the total intake in energy and carbohydrates and of candies in the total intake of lipids is also evident.

  12. Analysis of ten year return period floods in west african rivers

    Science.gov (United States)

    Nka Nnomo, Bernadette; Oudin, Ludovic; Paturel, Jean Emmanuel; Karambiri, Harouna; Ribstein, Pierre

    2014-05-01

    In West Africa, flood and flow are usually determined by using methods advocated by the FAO (1996) and developed by ORSTOM and CIEH researchers in the 1960s. However, the 1970s, 1980s, 1990s decades were characterized by very low precipitation amounts, leading to low stream flows in river basins, except in the Sahelian region where the impact of human activities led to a substantial increase of floods in some catchments. More recently, studies pointed out an increase in the frequency of intense rainfall events and an increase of flood events. Consequently, the reliability of conventional methods for flood estimation is questionable. In this work, we analyzed the trends of the ten-year return period rainfall and stream flow events for several catchments in the Sahelian and Sudanian regions. We used eleven tributaries of large river basins (Niger, Nakambe, Senegal, Gambia) for which daily rainfall and flow data were collected from national hydrological services of four countries over West Africa (Burkina Faso, Mali, Niger, Senegal). The conjoint use of rainfall and flow data allowed us to analyze the possible causality link between the two variables. Mann-Kendall, Pettitt and Hubert tests were used to detect trends and abrupt change points in the annual maximum time series.The quantification of change was assessed by computing 10-year return period rain and flow values on sliding sub periods in the long-term maxima time series with the GEV distribution. Trend tests on annual maximum flows time series showed mixed results depending on the location of the catchments: generally speaking, a decrease is observed for Sudanian catchments and an increase is observed for Sahelian catchments. On a period of 50 years (1950 - 2010) we pointed out an increase of 72% of the mean value of flood 10-year return period for a station like Kakassi in the sahelian region, with respect to the period before the detected disruption; while for a soudanian catchment like Fadougou, the average

  13. [Bilateral Congenital Multiple Pigmented Vitreous Cysts in a Three-year-old Girl: Ten Years Follow up].

    Science.gov (United States)

    Štěpánková, J; Hósová, M; Dotřelová, D

    2017-01-01

    The authors present a case report of a three-year-old female patient with bilateral multiple anterior vitreous cysts. During examination for intermittent esotropia of the right eye was diagnosed not only hypermetropia, astigmatism and anisometropia, but also pigmented changes in peripheral retrolental space of both eyes. Clinical examination under general anaesthesia revealed bilateral multiple pigmented immobile vitreous cysts. There were five almost spherical, translucent, but slightly pigmented cysts on its cover on the right eye and four similar on the left, but visible only with dilated pupils. A dilating of pupils was slow and required more mydriatics than in similar aged children. Follow up period is ten years now. Occlusion therapy of amblyopia was performed to nine years of age. Treatment of refractive error and esotropia with correction for hypermetropia, astigmatism and anisometropia continues. Best corrected visual acuity in thirteen-year-old girl is 1,0 in both eyes without any visual disturbances described by patient. Corrected visual acuity in each eye is 1,0, right eye with +3,5 D sph., -3,5D cyl., axis 175°, left eye with +7,5 D sph., -3,0 D cyl., axis 35°. Patient is otherwise healthy and without any mental deficit. Position of all cysts remains unchanged and stabile during the follow up period (with recommendation to avoid hits to the head for all time, mainly in sports). Formation and slow progression of partial cortical cataract in the area of contact of the lens and one cyst in inferonasal quadrant of the lens on the right eye is monitored. A lamellar retinal extrafoveal defect of posterior pole of the right eye was found by OCT imaging.Key words: vitreous cyst, idiopathic, congenital, bilateral, multiple, pigmented, immobile, hypermetropia, astigmatism, anisometropia, esotropia, cortical cataract, retinal lamellar extrafoveal defect, OCT.

  14. Urine Iodine Status of 8-10-Year Old School Children in Yazd Province during Ten Years (2007-2016

    Directory of Open Access Journals (Sweden)

    Yousof Naghiaee

    2017-08-01

    Full Text Available Background: Iodine is an essential element for growth and development and its inadequate intake leads to insufficient production of thyroid hormone. In developed countries iodine deficiency (ID is one of the reformable factors. So, this study determined urinary iodine (UI status of 8-10-year old school children in Yazd province during 2007 to 2016. Methods: This cross-sectional and descriptive study was conducted on 2236 students who were randomly selected from urban and rural regions with equal proportion of gender. Questionnaires were administered to gather the required descriptive data and then morning samples of urine were collected. Iodine concentration was determined with titration and acidic digestion. Data were analyzed through SPSS software. Results: During the study period, the percentage of students with UI of lower than 2 µg/dL, was zero and only 2.37 % of them had a UI level in the range of 2-4.90 µg/dL. Median of UI was 18.40 ± 7.70 µg/dL level of UI in normal range showed noticeable increase from 2013 to 2016. Level of normal UI in ten years was 79.02%. Conclusions: According to the results of this study, Yazd province was considered "IDD free" similar to some other provinces. Also, level of UI more than 30 µg/dL was decreased. It is clear that this approaches need continuous evaluation such as annual evaluation of UI in 8-10 years old students at province level and every five years evaluation at national level.

  15. Mechatronics methodology: 15 years of experience

    Directory of Open Access Journals (Sweden)

    Efren Gorrostieta

    2015-09-01

    Full Text Available This article presents a methodology to teach students to develop mechatronic projects. It was taught in higher education schools, in different universities in Mexico, in courses such as: Robotics, Control Systems, Mechatronic Systems, Artificial Intelligence, etc. The intention of this methodology is not only to achieve the integration of different subjects but also to accomplish synergy between them so that the final result may be the best possible in quality, time and robustness. Since its introduction into the educational area, this methodology was evaluated and modified for approximately five years, were substantial characteristics were adopted. For the next ten years, only minor alterations were carried out. Fifteen years of experience have proven that the methodology is useful not only for training but also for real projects. In this article, we first explain the methodology and its main characteristics, as well as a brief history of its teaching in different educational programs. Then, we present two cases were the methodology was successfully applied. The first project consisted in the design, construction and evaluation of a mobile robotic manipulator which aims to be used as an explosives ordnance device. In the second case, we document the results of a project assignment for robotics tasks carried out by students which were formerly taught with the methodology.

  16. Keeping Up with the Reality Show: A Ten-Years-Later Review of Surviving Teaching on the Internet

    Directory of Open Access Journals (Sweden)

    M. Louise Ripley

    2013-08-01

    Full Text Available A dozen years ago, I set out to teach my first Internet course at York University, a large urban Canadian university with 55,000+ students who are mainly commuters. Two years later I wrote an article titled, "Survivor!: When the Next Reality Show is You Teaching Your First Internet Course", in which I argued that there are ten major things you should not do when teaching on the Internet. Now ten years later, in this paper I revisit those recommendations to see if they still hold true, and to see if we need to add any new ones.

  17. Family religion and psychopathology in children of depressed mothers: ten-year follow-up.

    Science.gov (United States)

    Jacobs, Martha; Miller, Lisa; Wickramaratne, Priya; Gameroff, Marc; Weissman, Myrna M

    2012-02-01

    Previously we found that transmission of religion from mother to adult offspring as measured by correlations on ratings of personal importance of religion and frequency of attendance at religious services was hindered by maternal depression. Concordance of denomination, a measure indicating successful transmission of denomination within a mother and offspring pair, was associated with a 71% decreased risk of major depressive disorder (MDD) in offspring. This study attempts to replicate the findings in a younger generation of mothers who were the original offspring or spouse of the original offspring in the previous study, and their offspring. Mothers (N=45) and offspring (N=78) were assessed for MDD and anxiety using semi-structured clinical interviews (The Diagnostic Schedule for Affective Disorders and Schizophrenia Modified for the Anxiety Disorders) at two points across a ten-year interval. Religiosity was assessed by report of personal spirituality, frequency of attendance at religious services, and religious denomination Results partially replicate previous findings that maternal depression hinders the transmission of importance but not attendance or denomination to offspring. Concordance of denomination is protective, decreasing by 91% the likelihood of childhood anxiety or depression, independent of maternal depression. Limitations include small sample size that represents few denominations, limited assessments of religiosity, and inability to control for the possible confound of a close relationship between mother and offspring in our analyses. Family agreement and practice of religious denomination may be a robust protective source from MDD or anxiety for youth, independent of the effects of maternal depression. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

    Science.gov (United States)

    Kim, S.-H.; Afanador, R.; Barnhart, D. L.; Crofford, M.; Degraff, B. D.; Doleans, M.; Galambos, J.; Gold, S. W.; Howell, M. P.; Mammosser, J.; McMahan, C. J.; Neustadt, T. S.; Peters, C.; Saunders, J. W.; Strong, W. H.; Vandygriff, D. J.; Vandygriff, D. M.

    2017-04-01

    The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenance activities for cryomodules are introduced.

  19. Ten years of a model of aesthetic appreciation and aesthetic judgments : The aesthetic episode - Developments and challenges in empirical aesthetics.

    Science.gov (United States)

    Leder, Helmut; Nadal, Marcos

    2014-11-01

    About a decade ago, psychology of the arts started to gain momentum owing to a number of drives: technological progress improved the conditions under which art could be studied in the laboratory, neuroscience discovered the arts as an area of interest, and new theories offered a more comprehensive look at aesthetic experiences. Ten years ago, Leder, Belke, Oeberst, and Augustin (2004) proposed a descriptive information-processing model of the components that integrate an aesthetic episode. This theory offered explanations for modern art's large number of individualized styles, innovativeness, and for the diverse aesthetic experiences it can stimulate. In addition, it described how information is processed over the time course of an aesthetic episode, within and over perceptual, cognitive and emotional components. Here, we review the current state of the model, and its relation to the major topics in empirical aesthetics today, including the nature of aesthetic emotions, the role of context, and the neural and evolutionary foundations of art and aesthetics. © 2014 The British Psychological Society.

  20. Survival of the Scandinavian total ankle replacement (STAR): results of ten to nineteen years follow-up.

    Science.gov (United States)

    Frigg, Arno; Germann, Ursula; Huber, Martin; Horisberger, Monika

    2017-07-26

    The purpose of this study was to evaluate survival and clinical outcome of the Scandinavian total ankle replacement (STAR) prosthesis after a minimum of ten years up to a maximum of 19 years. Fifty STAR prostheses in 46 patients with end stage ankle osteoarthritis operated between 1996 and 2006 by the same surgeon (MH) were included. Minimal follow-up was ten years (median 14.6 years, 95% confidence interval [CI] 12.9-16.4). Clinical (Kofoed score) and radiological assessments were taken before the operation and at one, ten (+2), and 16 (±3) years after implantation. The primary endpoint was defined as exchange of the whole prosthesis or conversion to arthrodesis (def. 1), exchange of at least one metallic component (def. 2), or exchange of any component including the inlay (due to breakage or wear) (def. 3). Survival was estimated according to Kaplan-Meier. Further reoperations related to STAR were also recorded. The ten year survival rate was (def. 1) 94% (CI 82-98%), (def. 2) 90% (CI, 77-96%), and (def. 3) 78% (CI 64-87%). The 19-year survival rate was (def. 1) 91% (CI 78-97%), (def. 2) 75% (CI 53-88%), and (def. 3) 55% (CI 34-71%). Considering any re-operations related to STAR, 52% (26/50) of prostheses were affected by re-operations. Mean pre-operative Kofoed score was 49, which improved to 84 after one year (n = 50), to 90 after ten years (n = 46), and to 89 after 16 years (n = 28). The survival rate for def. 1 and 2 was high. However, re-operations occurred in 52% of all STAR prosthesis. Retrospective cohort study, evidence Level 4.

  1. Ten-year variability in fluxes, meteorology, and environmental conditions at a Colorado subalpine forest site

    Science.gov (United States)

    Burns, S. P.; Turnipseed, A.; Bowling, D. R.; Hu, J.; Monson, R. K.

    2009-12-01

    Changing meteorological and environmental conditions affect fluxes; model analysis has shown that environmental variability directly accounts for about half the interannual variability in net ecosystem exchange (NEE) of CO2 whereas the other 50% is due to biotic responses to these changing variables (Richardson et al. 2007). In our study, ten years (1998-2008) of turbulent flux measurements of heat, water vapor, and CO2 at the Niwot Ridge AmeriFlux site (Monson et al. 2002) are examined with respect to meteorological conditions (atmospheric temperature, stability, precipitation, and cloudiness) as well as changes in environmental conditions, such as snow depth and soil moisture. The typical yearly cycle and an estimate of the magnitude of year-to-year variability in the diurnal fluxes and other variables for a high-elevation subalpine forest ecosystem are presented. Wintertime ecosystem respiration has an average 30-min NEE of 0.62 μmol m-2 s-1 with an interannual range between 0.5-1 μmol m-2 s-1. Uptake of CO2 in late summer has an average NEE of -0.71 μmol m-2 s-1 with an interannual range between -0.1 to -1.5 μmol m-2 s-1. Previous studies at the Niwot Ridge AmeriFlux site have described the importance of photosynthetic photon flux density (PPFD) (Monson et al. 2002) and also growing season length (Hu et al. 2009) on NEE. Water isotope ratios analyzed by Hu et al. (2009) have shown that trees at the site primarily rely on water from snowmelt to sustain them throughout the summer; combining this result with the SIPNET model, Hu et al. conclude that there is a limited connection between summer precipitation and the cumulative annual gross primary production (GPP). We have tested this conclusion more explicitly by examining the response of NEE to specific precipitation events and the effect of extended dry periods on the diel cycle of the fluxes, CO2 mole fraction, sap flow, and other meteorological and soil variables. Additionally, we examine the connection

  2. The Ten Most Important Reading Research Studies Published during the Last 25 Years.

    Science.gov (United States)

    Peterson, Gordon

    The ten reading research studies published since 1955 and deemed by the author "most important" in terms of quality, originality, and applicability to elementary reading instruction are described in this report. Discussed are studies on reading approaches by Russell Stauffer and by Neville Bennett; a study on reading readiness by Audrey…

  3. Campylobacter antimicrobial resistance in Peru: a ten-year observational study

    Directory of Open Access Journals (Sweden)

    Pollett Simon

    2012-08-01

    Full Text Available Abstract Background Campylobacter jejuni and Campylobacter coli are food-borne pathogens of great importance and feature prominently in the etiology of developing world enteritis and travellers’ diarrhoea. Increasing antimicrobial resistant Campylobacter prevalence has been described globally, yet data from Peru is limited. Our objective was to describe the prevalence trends of fluoroquinolone and macrolide-resistant C. jejuni and C. coli stool isolates from three regions in Peru over a ten-year period. Methods Surveillance for enteric pathogens was conducted in Lima, Iquitos and Cusco between 2001 and 2010. Campylobacter stool isolates were tested for susceptibilities to ciprofloxacin, azithromycin and erythromycin. Susceptibilities were reviewed for 4652 isolates from Lima ( n = 3419, Iquitos ( n = 625 and Cusco ( n = 608. Results Comparing the study periods of 2001-2005 and 2006-2010, prevalence of ciprofloxacin-resistant C. jejuni isolates rose in the study areas of Lima (73.1% to 89.8%, p p C. coli rates also increased in Lima (48.1% to 87.4%, p p = 0.005. Small but significant increases in azithromycin-resistant and erythromycin-resistant C. jejuni prevalence were noted in Iquitos (2.2% to 14.9%, p p = 0.002, and erythromycin-resistant C. coli rates increased in Lima (0.0% to 5.3%, p = 0.038. The prevalence of C. jejuni isolates resistant to both ciprofloxacin and azithromycin increased in Iquitos (0.3% to 14.9%, p C. jejuni isolates resistant to both ciprofloxacin and erythromycin rose in Iquitos (0.0% to 14.9%, p C. coli prevalence increased in Lima (0.0% to 5.3%, p = 0.034. Conclusions These results have implications for the empirical management of enterocolitis in Peru. Ongoing surveillance is essential to guide appropriate antimicrobial use in this setting. Local epidemiological studies to explore the relationship between increasing antimicrobial resistance and agricultural or human antibiotic

  4. [Good agricultural practice (GAP) of Chinese materia medica (CMM) for ten years: achievements, problems and proposals].

    Science.gov (United States)

    Guo, Lan-Ping; Zhang, Yan; Zhu, Shou-Dong; Wang, Gui-Hua; Wang, Xiu; Zhang, Xiao-Bo; Chen, Mei-Lan; He, Ya-Li; Han, Bang-Xing; Chen, Nai-Fu; Huang, Lu-Qi

    2014-04-01

    This paper aims to summarize the achievements during the implementation process of good agricultural practice (GAP) in Chinese Materia Medica (CMM), and on basis of analyzing the existing problems of GAP, to propose further implementation of GAP in TCM growing. Since the launch of GAP in CMM growing ten years ago, it has acquired great achievements, including: (1) The promulgation of a series of measures for the administration of the GAP approval in the CMM growing; (2) The expanded planting area of CMM; (3) The increased awareness of standardized CMM growing among farmers and enterprises; (4) The establishment of GAP implementation bases for CMM growing; (5) The improvement of theory and methodology for CMM growing; (6) The development of a large group of experts and scholars in GAP approval for CMM production. The problems existing in the production include: (1) A deep understanding of GAP and its certification is still needed; (2) The distribution of the certification base is not reasonable; (3) The geo-economics effect and the backward farming practices are thought to be the bottlenecks in the standardization of CMM growing and the scale production of CMM; (4) Low comparative effectiveness limits the development of the GAP; (5) The base of breeding improved variety is blank; (6) The immature of the cultivation technique lead to the risk of production process; (7) The degradation of soil microbial and the continuous cropping obstacle restrict the sustainable development of the GAP base. To further promote the health and orderly GAP in the CMM growing, the authors propose: (1) To change the mode of production; (2) To establish a sound standard system so as to ensure quality products for fair prices; (3) To fully consider the geo-economic culture and vigorously promote the definite cultivating of traditional Chinese medicinal materials; (4) To strengthen the transformation and generalization of basic researches and achievements, in order to provide technical

  5. Transplante alogênico de células-tronco hematopoéticas em leucemias agudas: a experiência de dez anos do Hospital das Clínicas da UFMG Allogeneic hematopoietic stem cells transplantation in acute leukemia: ten years of experience in the Hospital das Clínicas - UFMG

    OpenAIRE

    Rosana M. Lamego; Nelma C. D. Clementino; Costa,Ângela L. B.; Marçal J. M. Oliveira; Henrique Bittencourt

    2010-01-01

    As leucemias agudas são doenças com alta morbimortalidade para as quais o transplante alogênico de medula óssea é uma opção terapêutica eficaz. Neste artigo, relatamos a experiência de um centro brasileiro com pacientes apresentando leucemia aguda que receberam um enxerto de medula óssea ou células-tronco periféricas de um doador familiar HLA idêntico no período de julho de 1995 a dezembro de 2005. Foi realizado um estudo de coorte retrospectivo, analisando dados de 125 pacientes com mediana ...

  6. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

    Science.gov (United States)

    May, Margaret T.; Vehreschild, Janne; Obel, Niels; Gill, Michael John; Crane, Heidi; Boesecke, Christoph; Samji, Hasina; Grabar, Sophie; Cazanave, Charles; Cavassini, Matthias; Shepherd, Leah; d’Arminio Monforte, Antonella; Smit, Colette; Saag, Michael; Lampe, Fiona; Hernando, Vicky; Montero, Marta; Zangerle, Robert; Justice, Amy C.; Sterling, Timothy; Miro, Jose; Ingle, Suzanne; Sterne, Jonathan A. C.

    2016-01-01

    Objectives To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996–1999 and survived for more than ten years. Methods We used data from 18 European and North American HIV cohort studies contributing to the Antiretroviral Therapy Cohort Collaboration. We followed up patients from ten years after start of combination antiretroviral therapy. We estimated overall and cause-specific mortality rate ratios for age, sex, transmission through injection drug use, AIDS, CD4 count and HIV-1 RNA. Results During 50,593 person years 656/13,011 (5%) patients died. Older age, male sex, injecting drug use transmission, AIDS, and low CD4 count and detectable viral replication ten years after starting combination antiretroviral therapy were associated with higher subsequent mortality. CD4 count at ART start did not predict mortality in models adjusted for patient characteristics ten years after start of antiretroviral therapy. The most frequent causes of death (among 340 classified) were non-AIDS cancer, AIDS, cardiovascular, and liver-related disease. Older age was strongly associated with cardiovascular mortality, injecting drug use transmission with non-AIDS infection and liver-related mortality, and low CD4 and detectable viral replication ten years after starting antiretroviral therapy with AIDS mortality. Five-year mortality risk was <5% in 60% of all patients, and in 30% of those aged over 60 years. Conclusions Viral replication, lower CD4 count, prior AIDS, and transmission via injecting drug use continue to predict higher all-cause and AIDS-related mortality in patients treated with combination antiretroviral therapy for over a decade. Deaths from AIDS and non-AIDS infection are less frequent than deaths from other non-AIDS causes. PMID:27525413

  7. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy.

    Directory of Open Access Journals (Sweden)

    Adam Trickey

    Full Text Available To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996-1999 and survived for more than ten years.We used data from 18 European and North American HIV cohort studies contributing to the Antiretroviral Therapy Cohort Collaboration. We followed up patients from ten years after start of combination antiretroviral therapy. We estimated overall and cause-specific mortality rate ratios for age, sex, transmission through injection drug use, AIDS, CD4 count and HIV-1 RNA.During 50,593 person years 656/13,011 (5% patients died. Older age, male sex, injecting drug use transmission, AIDS, and low CD4 count and detectable viral replication ten years after starting combination antiretroviral therapy were associated with higher subsequent mortality. CD4 count at ART start did not predict mortality in models adjusted for patient characteristics ten years after start of antiretroviral therapy. The most frequent causes of death (among 340 classified were non-AIDS cancer, AIDS, cardiovascular, and liver-related disease. Older age was strongly associated with cardiovascular mortality, injecting drug use transmission with non-AIDS infection and liver-related mortality, and low CD4 and detectable viral replication ten years after starting antiretroviral therapy with AIDS mortality. Five-year mortality risk was <5% in 60% of all patients, and in 30% of those aged over 60 years.Viral replication, lower CD4 count, prior AIDS, and transmission via injecting drug use continue to predict higher all-cause and AIDS-related mortality in patients treated with combination antiretroviral therapy for over a decade. Deaths from AIDS and non-AIDS infection are less frequent than deaths from other non-AIDS causes.

  8. Experiences of the first year as father.

    Science.gov (United States)

    Premberg, Asa; Hellström, Anna-Lena; Berg, Marie

    2008-03-01

    The importance of fathers' participation for development of the child and the well-being of the family is recognized from earlier research. In Sweden, legislation allows fathers to share the parental leave equally with the mother even so fathers only use a small of their paid leave. The aim of the study was to explore experiences of the first year as a father. A phenomenological life world approach was used. Ethical approval was obtained. Ten men, recruited by a purposive sample, were interviewed 12-14 months after the delivery of their first child. The data collection was performed during June and August 2004 in the south-west area of Sweden. The essence of the experiences of the first year as father was to place the baby in the centre without giving up one's own person. The child provided warmth and happiness in the family and men experienced a deeper relationship to their partner. The contact between father and child was facilitated by engagement and time spent alone with the child. The major constituents identified from the findings were 'To be overwhelmed', 'To master the new situation' and 'To get a new completeness in life'. To master fatherhood maintenance of integrity and possibility to develop an independent relationship with the child is important. Fathers are invited to participate in postnatal childbirth education but the activities address women's needs and it is doubtful if the fathers benefit from participation. Though fathers entered the delivery room some decades ago, as a support to the woman, health personnel of today must be aware of fathers' own needs and the impact gender aspects have on their professional support.

  9. A quantitative study of TWiki at CERN after ten years of use

    CERN Document Server

    Jones, Peter L

    2016-01-01

    The European Organization for Nuclear Research known as CERN [1], is the home of the Large Hadron Collider (LHC) [2] where physicists are recreating conditions close to those at the origin of the Universe. Although the LHC is based at CERN over 10,000 scientists and engineers from over 100 countries and hundreds of universities and laboratories collaborate on this project. TWiki [3] is an online collaboration platform and was introduced at CERN at the request of the LHC experiments, ALICE, ATLAS, CMS and LHCb have all used TWiki since its introduction. By analyzing the TWiki website statistics from 2006 until April 2016 this paper presents a quantitative study of how TWiki has been put into practice. The results will give a general picture of who is using the system and how this has evolved over the years.

  10. Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study

    Directory of Open Access Journals (Sweden)

    van den Berg Bellis

    2012-09-01

    Full Text Available Abstract Background Disaster experiences have been associated with higher prevalence rates of (mental health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD. Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1, eighteen months (wave 2 and four years post-disaster (wave 3. Ten years post-disaster (wave 4 the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score and some disaster-related experiences (such as house destroyed, injured, confusion were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and

  11. Dez anos de experiência com a substituição da valva aórtica com homoenxertos valvares aórticos implantados pela técnica da substituição total da raiz Ten years experience of aortic valve replacement with aortic homograft root replacement

    Directory of Open Access Journals (Sweden)

    Francisco Costa

    2006-06-01

    áximo variando entre 3 a 47 mmHg (média de 14,5 mmHg, sendo que apenas dois pacientes apresentavam gradiente superior a 40mmHg. Insuficiência valvar moderada foi encontrada em quatro pacientes. CONCLUSÕES: Os resultados imediatos e tardios com a substituição da valva aórtica por homoenxerto valvar criopreservado foram excelentes, com boa capacidade funcional e baixa morbi-mortalidade tardia. O único fator de risco para a degeneração tecidual primária foi a idade do paciente menor que 20 anos. Homoenxertos aórticos representam uma excelente opção para pacientes com idade acima de 40-50 anos, especialmente naqueles com contra-indicação ou que não desejem fazer o uso de anticoagulantes.OBJECTIVE: To evaluate the imediate and late results of 10 years of aortic valve root replacement with aortic homografts and to identify possible risk factors related with homograft primary tissue failure. METHODS: Between May 1995 and January 2006, 282 patients with a mean age of 52.8±16.6 years were submitted to aortic valve root replacement with an aortic homografts. The most prevalent etiologies were calcified bicuspid aortic valves and senile degeneration, corresponding to 49% of the cases. Forty-seven patients were reoperations and acute bacterial endocarditis were present in 26. Associated procedures were necessary in 113 patients. The homograft was implanted as a root replacement in all. Follow-up time varied between 1 and 129 months (mean= 41±25 months. RESULTS: Early overall mortality was 7%, with only 2.6% for cases of aortic valve replacement in isolation. Of the 262 patients discharged from hospital, it was possible to obtain clinical and echocardiographic evaluations in 209. Fifty-one patients (20% were lost in the follow-up. There were 17 late deaths between the 2nd and 81st postoperative months, which resulted in an actuarial survival rate of 90% and 80.1% at 5 and 10 years respectively. There were eight thromboembolic events (four early and four late, for a

  12. Estuarine River Data for the Ten Thousand Islands Area, Florida, Water Year 2005

    Science.gov (United States)

    Byrne, Michael J.; Patino, Eduardo

    2008-01-01

    The U.S. Geological Survey collected stream discharge, stage, salinity, and water-temperature data near the mouths of 11 tributaries flowing into the Ten Thousand Islands area of Florida from October 2004 to June 2005. Maximum positive discharge from Barron River and Faka Union River was 6,000 and 3,200 ft3/s, respectively; no other tributary exceeded 2,600 ft3/s. Salinity variation was greatest at Barron River and Faka Union River, ranging from 2 to 37 ppt, and from 3 to 34 ppt, respectively. Salinity maximums were greatest at Wood River and Little Wood River, each exceeding 40 ppt. All data were collected prior to the commencement of the Picayune Strand Restoration Project, which is designed to establish a more natural flow regime to the tributaries of the Ten Thousand Islands area.

  13. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

    DEFF Research Database (Denmark)

    Trickey, Adam; May, Margaret T; Vehreschild, Jorg-Janne

    2016-01-01

    OBJECTIVES: To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996-1999 and survived for more than ten years. METHODS: We used data from 18 European and North American HIV cohort studies contributing to the Antiretro...

  14. Dying from cancer or other chronic diseases in the Netherlands: ten-year trends derived from death certificate data.

    NARCIS (Netherlands)

    Velden, L.F.J. van der; Francke, A.L.; Hingstman, L.; Willems, D.L.

    2009-01-01

    BACKGROUND: For the further development of palliative care, it is relevant to gain insight into trends in non-acute mortality. The aim of this article is twofold: (a) to provide insight into ten-year trends in the characteristics of patients who died from cancer or other chronic diseases in the

  15. Dying from cancer or other chronic diseases in the Netherlands: ten-year trends derived from death certificate data

    NARCIS (Netherlands)

    van der Velden, Lud Fj; Francke, Anneke L.; Hingstman, Lammert; Willems, Dick L.

    2009-01-01

    ABSTRACT: BACKGROUND: For the further development of palliative care, it is relevant to gain insight into trends in non-acute mortality. The aim of this article is twofold: (a) to provide insight into ten-year trends in the characteristics of patients who died from cancer or other chronic diseases

  16. 78 FR 57573 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Science.gov (United States)

    2013-09-19

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Aspen AGENCY: Environmental Protection Agency (EPA). ACTION...

  17. 78 FR 56185 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-09-12

    ... From the Federal Register Online via the Government Publishing Office ] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Fort Collins AGENCY: Environmental Protection Agency...

  18. 78 FR 46861 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-08-02

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Greeley AGENCY: Environmental Protection Agency (EPA...

  19. 78 FR 41342 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Science.gov (United States)

    2013-07-10

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Ca on City AGENCY: Environmental Protection Agency (EPA...

  20. 78 FR 46552 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-08-01

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Colorado Springs AGENCY: Environmental Protection...

  1. Ten years of sustainability evaluation using the MESMIS framework: Lessons learned from its application in 28 Latin American case studies

    NARCIS (Netherlands)

    Speelman, E.N.; López Ridaura, S.; Aliana-Colomer, N.; Astier, M.; Masera, O.

    2007-01-01

    This paper focuses on sustainability evaluation and, more specifically, it describes and analyses the Indicator-based Framework for Evaluation of Natural Resource Management Systems (MESMIS, its Spanish acronym), ten years after its development. This framework fulfilled a pioneering role by

  2. Minimum ten-year follow-up of acetabular fracture fixation from the Irish tertiary referral centre.

    LENUS (Irish Health Repository)

    Magill, Paul

    2012-04-01

    Successful outcome from acetabular fracture fixation is multi-factorial. Long-term results are not frequently reported. Pooling such data from high output centres will help progress acetabular fixation. This paper presents the first ten-year data from the Irish tertiary referral centre.

  3. Ten Years On, the Kimberley Process Certification Scheme and Zimbabwe's Marange and "Conflict Diamonds": Lessons to be learnt

    Directory of Open Access Journals (Sweden)

    Nazreen Shaik-Peremanov

    2014-04-01

    Full Text Available TEN YEARS ON, THE KIMBERLEY PROCESS CERTIFICATION SCHEME AND ZIMBABWE’S MARANGE AND "CONFLICT DIAMONDS": LESSONS TO BE LEARNT N Shaik-Peremanov* SUMMARY Remove by editor - Prof Christa Rautenbach email: Christa.Rautenbach@nwu.ac.za

  4. High satisfaction rate ten years after bilateral prophylactic mastectomy - a longitudinal study.

    Science.gov (United States)

    Wasteson, E; Sandelin, K; Brandberg, Y; Wickman, M; Arver, B

    2011-07-01

    Women from families with an increased risk for breast/ovarian cancer have undergone bilateral prophylactic mastectomy (BPM) since the early 1990s at the Karolinska University Hospital in Sweden. Perceptions of BPM as reported by the first women who underwent the procedure have previously been evaluated on a short-term basis (1-3 years). The present study aims to evaluate the long-term (10 years) physical and psychological consequences of BPM in the same cohort of women. Some of the very first women to undergo BPM participated in the present interview study (n= 13). The semi-structured interviews focused on the women's long-term experiences related to BPM and immediate breast reconstruction. Overall, the women were satisfied with their decision to undergo BPM and perceived a negligible remaining risk of getting breast cancer. For most women, the operation had not resulted in changes in family life or lifestyle (n= 8), although some described that the relationship with their spouse was affected (8/13), either in a negative (n= 5) or positive (n= 3) way. The cosmetic results were mainly positive (n= 10). Recurrent counselling and support during the whole process of decision, treatment and follow up is recommended. © 2010 Blackwell Publishing Ltd.

  5. Evaluación del Programa de Intercambio de Jeringuillas en el Centro Penitenciario de Pereiro de Aguiar (Ourense: diez años de experiencia Evaluation of needle exchange program at Pereiro de Aguiar prison (Ourense, Spain: ten years of experience

    Directory of Open Access Journals (Sweden)

    V. Ferrer-Castro

    2012-06-01

    Full Text Available Objetivos: Evaluar la eficacia de un programa de intercambio de jeringuillas (PIJ en una prisión para reducir la prevalencia de infecciones asociadas al uso de drogas intravenosas, y conocer la aceptación del programa por internos y funcionarios del centro penitenciario. Material y métodos: Estudio observacional con cortes transversales al inicio, 6 y 12 meses y 10 años de desarrollo del programa. Se realizaron entrevistas a los usuarios del programa y encuestas a muestras accidentales de funcionarios en los distintos cortes, y a una muestra aleatoria de internos a los 10 años. Se registraron diariamente los indicadores de actividad del programa, y se valoró la prevalencia de infección por VIH, hepatitis B y C al inicio y a los 10 años. Para el análisis estadístico utilizamos la prueba ji-cuadrado con la corrección de Yates en caso necesario. Resultados: Durante estos diez años se suministraron 15.962 jeringuillas a 429 usuarios (media de 20,2 usuarios/mes, recuperándose 11.327 (70,9%. La prevalencia de infección por VIH pasó del 21% en 1999 al 8,5% en 2009, la de VHC del 40% al 26,1% (pObjectives: To evaluate the effectiveness of NEPs in prison to reduce the prevalence of infections associated with intravenous drug use and to know more about acceptance of the program by inmates and staff. Material and methods: cross-sectional observational study at baseline, 6 and 12 months and 10 years of program development. Interviews were conducted with program users, as well as random sample surveys of officials at the various cuts, and a random sample of inmates from the centre after10 years. Activity indicators of the program were recorded continuously, and the prevalence of HIV, HBV and HCV at baseline and after 10 years was evaluated. For the statistical analysis, the chi-square test was used with the Yates correction when necessary. Results: In ten years we have supplied a total of 15,962 syringes to 429 users, (average 20.2 users

  6. Renal Cell Carcinoma with venous neoplastic thrombosis: A ten years review

    Directory of Open Access Journals (Sweden)

    Giacomo Maria Pirola

    2013-12-01

    Full Text Available Purpose: To review the 10-year experience of our urological unit in the surgical management of renal cell carcinoma (RCC with neoplastic tumor thrombosis focusing on postoperative survival. Materials and Methods: We underwent a retrospective analysis of the patients treated for this pathology during the last decade 2002-2012, stratifying them by tumor thrombus level and histological subtype. Kaplan-Meyer curves were used to assess survival. Results: Overall, 67 patients underwent surgery for RCC with neoplastic tumoral thrombosis in the period under review. 60 were clear cell RCC, 4 were urothelial papillary tumors of the renal pelvis and 3 were rare histotypes, as a nefroblastoma, a spinocellular tumor of the renal pelvis and an unclassifiable renal carcinoma. Thrombus level was I in 40 cases, II in 17, III in 2 and IV in 8 patients. We report the main postoperative complications and our survival data, with mean follow up of 36 months. Tumor stage is the most important variable in predicting survival. Patients with N0M0 disease had 70% survival at 36 months, instead of 20% for those with primitive metastatic tumor. Conclusion: Our survival results fit with the main reports in literature and our surgical management was completely in keeping with international guidelines. We did not observe relevany post-operative complications, except of hemorrhagic ones that occurred in 6 patients (9% of total and were always successfully managed. Eighteen patients (26.87% of total underwent caval filter positioning, without evidence of complications during its positioning or removal. Life expectancy was particularly low for the cases of RCC without clear cell histotype (7 cases in our series, 10.4% of total that always was less than one year from surgery.

  7. LECA refurbishment project or how to get ready for the next ten years

    Energy Technology Data Exchange (ETDEWEB)

    Boussard, Francois; Bois, Dominique; Blanc, Jean Yves

    2005-01-01

    Around 1995, CEA decided a strategy for its hot laboratories: Closing LAMA - Grenoble and LHA - Saclay, after RM2 - Fontenay-aux-Roses. Refurbishing and gathering irradiated material studies in LECI - Saclay. Refurbishing LECA - Cadarache for irradiated fuel examinations. Reprocessing pilot experiments being located in Atalante - Marcoule. Started up in 1964, LECA has got an exploitation license up to August 2005. In 2001, safety authorities agreed to extend it up to 2015, provided an extensive refurbishment is undertaken which includes civil engineering works to achieve the building earthquake resistance, based on 3D-computations and withstanding maximum historically likely earthquake, improving confinement by decontaminating, adding steel boxes inside cells, changing ventilation system and creating a mobile upper cell on the cell roof, changing power supplies, shielded glasses and most manipulators, improving travelling crane, fire protection, radioactivity monitoring and alarms, installing a new device for characterizing and evacuating wastes, decreasing the fissile mass stored inside the facility (source term). Most of the work should be ended by the end of 2005. Afterwards five cells, which do not withstand earthquake, will be deconstructed within 3 years. By mid 2004, 60 % of tasks are completed and all contracts are awarded. The total final cost is 97 M Euro, 80% of which regarding the only LECA refurbishment. (Author)

  8. Ross operation: 16-year experience.

    Science.gov (United States)

    Elkins, Ronald C; Thompson, David M; Lane, Mary M; Elkins, C Craig; Peyton, Marvin D

    2008-09-01

    We performed a review of a consecutive series of 487 patients undergoing the Ross operation to identify surgical techniques and clinical parameters that affect outcome. We performed a prospective review of consecutive patients from August 1986 through June 2002 and follow-up through August 2004. Patient age was 2 days to 62 years (median, 24 years), and 197 patients were less than 18 years of age. The Ross operation was performed as a scalloped subcoronary implant in 26 patients, an inclusion cylinder in 54 patients, root replacement in 392 patients, and root-Konno procedure in 15 patients. Clinical follow-up in 96% and echocardiographic evaluation in 77% were performed within 2 years of closure. Actuarial survival was 82% +/- 6% at 16 years, and hospital mortality was 3.9%. Freedom from autograft failure (autograft reoperation and valve-related death) was 74% +/- 5%. Male sex and primary diagnosis of aortic insufficiency (no prior aortic stenosis) were significantly associated with autograft failure by means of multivariate analysis. Freedom from autograft valve replacement was 80% +/- 5%. Freedom from endocarditis was 95% +/- 2%. One late thromboembolic episode occurred. Freedom from allograft reoperation or reintervention was 82% +/- 4%. Freedom from all valve-related events was 63% +/- 6%. In children survival was 84% +/- 8%, and freedom from autograft valve failure was 83% +/- 6%. The Ross operation provides excellent survival in adults and children willing to accept a risk of reoperation. Male sex and a primary diagnosis of aortic insufficiency had a negative effect on late results.

  9. Clinical diagnosis of syphilis: a ten-year retrospective analysis in a South Australian urban sexual health clinic.

    Science.gov (United States)

    Forrest, C E; Ward, A

    2016-12-01

    National notifications for infectious syphilis in Australia have increased in recent years. Outside of sexual health clinics, junior clinicians seldom encounter this disease in its infectious stage (primary, secondary and early latent). With such a variable clinical presentation, textbook teaching is no substitute for real-life experience. The importance of accurate classification and staging of disease is relevant to the risk of transmission and determines treatment duration. In this article, the authors review the clinical presentation of syphilis over ten years in an urban sexual health clinic with a focus on the clinical presentation and diagnosis of infectious syphilis, in particular secondary syphilis, compared with that outlined in the Australian National Notifiable Diseases Surveillance System guidelines. This retrospective review of all patients diagnosed with syphilis at an urban sexual health clinic showed that between 2005 and 2015, 226 cases of syphilis were diagnosed. Documentation of impression of clinical staging of disease was present in 46% of the cases. Seventeen of these cases were recorded as secondary syphilis. The criteria used by clinicians to diagnose the secondary syphilis cases were consistent with criteria defined by the Australian National Notifiable Diseases Surveillance System. All cases of secondary syphilis had at least one cutaneous manifestation of disease. The demographic of the cohort of syphilis cases was consistent with that recorded in the literature. This review showed that the clinician's diagnosis of secondary syphilis in this service is consistent with the National Notifiable Diseases Surveillance System guidelines. Continuing education of junior medical staff is important to facilitate diagnosis and improve documentation of clinical staging, minimise disease transmission and ensure appropriate treatment. © The Author(s) 2016.

  10. A Ten Year Study of Salary Differential by Sex through a Regression Methodology.

    Science.gov (United States)

    Williams, John Delane; And Others

    A 10-year study of salary differential by sex was undertaken at the University of North Dakota using a multiple regression methodology, with rank, discipline, degree, years in department, years in current rank, and sex as predictors. The sex variable evidenced lower salaries for women when controlling for the other variables throughout the study…

  11. What do you want to be in ten years? - Advising meteorology students in the post-Twister era

    Science.gov (United States)

    Snow, J. T.; Hempe, M.

    2012-12-01

    "What do you want to be in ten years?' This is a question we ask our students, freshmen and transfer, when they first arrive in the College student services center. Often the answer is "I don't know. I just want to be in meteorology." This response leads to a discussion of career opportunities in meteorology and related fields, including what might be called faux-careers, such as professional storm chasing and weather tour operations. (Students often have been misled by what they have seen in television shows.) Many students arrive on our doorstep with their heart set on a degree in meteorology, but lack knowledge of what the field is about or how challenging a meteorology degree program really is. We find ourselves spending a great deal of time convincing students that they need to explore the real opportunities in meteorology and related fields, which are many. Fortunately, because of the concentration of University and federal weather organizations in the National Weather Center and private sector weather companies in adjacent buildings, we are able to show concrete examples of real careers by means of tours, job shadowing, and introductions to alumni employed in these organizations. Also, as the students' progress in their studies, they discover the many opportunities for undergraduate employment, research experiences, and internships in these same organizations, through which they gain an appreciation for what constitutes a real career in modern meteorology. Further, many of today's careers in meteorology require a broad, global perspective. Unfortunately, many meteorology students have not traveled widely, but again have only seen what the media provides about distant lands and peoples. Accordingly, we encourage our undergraduate students to take advantage of our unique opportunities for overseas experiences in meteorology. Through arrangements with the met programs at the University of Reading (England), Monash University (Australia), and University of

  12. Ten-Year Follow-Up of Desarthrodesis of the Knee Joint 41 Years after Original Arthrodesis for a Bone Tumor

    OpenAIRE

    Ahmed Hamed Kassem Abdelaal; Norio Yamamoto; Katsuhiro Hayashi; Akihiko Takeuchi; Shinji Miwa; Hiroyuki Inatani; Hiroyuki Tsuchiya

    2015-01-01

    Introduction. The main indication for knee arthrodesis in tumor surgery is a tumor that requires an extensive resection in which the joint surface cannot be preserved. We report a patient that had knee desarthrodesis 41 years after giant cell tumor resection followed by a knee arthrodesis. This is the longest reported follow-up after desarthrodesis and conversion to total knee arthroplasty (TKA), almost ten years. Case Report. A 71-year-old man with a distal femoral giant cell tumor had under...

  13. Investigation of sea level around the island of Gavdos from ten years of TOPEX/POSEIDON satellite altimetry data

    Directory of Open Access Journals (Sweden)

    A.C. BANKS

    2004-05-01

    Full Text Available The European Union project ‘GAVDOS’ (MERTIKAS & PAVLIS, 1999 has been designed to lead to the establishment of a calibration and sea level monitoring site for the JASON-1 and ENVISAT satellites as well as the GLObal Sea level monitoring System (GLOSS. Within the context of this project, nearly ten years of TOPEX/POSEIDON satellite altimetry data (cycle 1 to 364 from the vicinity of the Gavdos Island (Crete, Greece have been processed and analysed. The results presented here are from the application of a method that incorporates the calculation of a corrected sea surface height from the altimetry data, along-track and cross-track data interpolation because of orbital drift, near coastal error filtering, and the use of a new geoid for the area. This method was applied in order to create ten year time series of sea level and associated parameters for the area around Gavdos island. The results reveal the pattern of sea level and local seasonal cycle around Gavdos over the last ten years.

  14. Ten years of invasion: Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) in Britain

    Science.gov (United States)

    Roy, Helen E; Brown, Peter M J

    2015-01-01

    1. Harmonia axyridis was first recorded in Britain in 2004. Two subsequent earlier records were received from 2003. 2. The UK Ladybird Survey, a citizen science initiative involving online recording, was launched in 2005 to encourage people across Britain to track the spread of H. axyridis. Tens of thousands of people have provided records of H. axyridis and other species of ladybirds, creating an invaluable dataset for large-scale and long-term research. Declines in the distribution of seven (of eight assessed) native species of ladybird have been demonstrated, and correlated with the arrival of H. axyridis, using the records collated through the UK Ladybird Survey. 3. Experimental research and field surveys have also contributed to our understanding of the ecology of H. axyridis and particularly the process of invasion. Harmonia axyridis arrived in Britain through dispersal and introduction events from regions in which it was deliberately released as a biological control agent. The rapid spread of this species has been attributed to its high natural dispersal capability by means of both flight and anthropogenic transport. A number of factors have contributed to the successful establishment and indeed dominance of this polymorphic species within aphidophagous guilds, including high reproductive capacity, intra-guild predation, eurytopic nature, high resistance to natural enemies within the invaded range, and potentially phenotypic plasticity. 4. The global invasion by H. axyridis and subsequent research on this species has contributed to the general understanding of biological invasions. PMID:26435571

  15. RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies

    Directory of Open Access Journals (Sweden)

    Zhang Haiyu

    2007-12-01

    Full Text Available Abstract Background The development of protocols for RNA extraction from paraffin-embedded samples facilitates gene expression studies on archival samples with known clinical outcome. Older samples are particularly valuable because they are associated with longer clinical follow up. RNA extracted from formalin-fixed paraffin-embedded (FFPE tissue is problematic due to chemical modifications and continued degradation over time. We compared quantity and quality of RNA extracted by four different protocols from 14 ten year old and 14 recently archived (three to ten months old FFPE breast cancer tissues. Using three spin column purification-based protocols and one magnetic bead-based protocol, total RNA was extracted in triplicate, generating 336 RNA extraction experiments. RNA fragment size was assayed by reverse transcription-polymerase chain reaction (RT-PCR for the housekeeping gene glucose-6-phosphate dehydrogenase (G6PD, testing primer sets designed to target RNA fragment sizes of 67 bp, 151 bp, and 242 bp. Results Biologically useful RNA (minimum RNA integrity number, RIN, 1.4 was extracted in at least one of three attempts of each protocol in 86–100% of older and 100% of recently archived ("months old" samples. Short RNA fragments up to 151 bp were assayable by RT-PCR for G6PD in all ten year old and months old tissues tested, but none of the ten year old and only 43% of months old samples showed amplification if the targeted fragment was 242 bp. Conclusion All protocols extracted RNA from ten year old FFPE samples with a minimum RIN of 1.4. Gene expression of G6PD could be measured in all samples, old and recent, using RT-PCR primers designed for RNA fragments up to 151 bp. RNA quality from ten year old FFPE samples was similar to that extracted from months old samples, but quantity and success rate were generally higher for the months old group. We preferred the magnetic bead-based protocol because of its speed and higher quantity of

  16. Ten Years’ Experience with an E-Learning Lecture Series on Cancer Biology and Pharmacology

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2013-01-01

    Full Text Available In life sciences, the internet is an indispensable medium for research, but has not yet realized its full potential for teaching. The concept of e-learning has been developed over the past decades for undergraduate, graduate and postgraduate programs. We set up an e-learning lecture on cancer biology and pharmacology that was first offered in 2003 to students of Molecular Biotechnology at the University of Heidelberg and to students of Pharmacy at the University of Mainz, Germany. The present paper recapitulates the first decade of experiences with this e-learning lecture from both the students’ and the teachers’ perspectives. A total of 317 students during the past 10 years participated in a survey. In general, the students enjoyed the possibilities that self-controlled learning offers. E-learning interested them as a novel educational method. They felt quite comfortable listening to the material despite the interdisciplinary nature of the lectures, which included molecular biological, pharmacological and medical aspects of cancer biology and pharmacology. This lecture was the first e-learning experience for the majority of students, and their impressions were generally positive. The students not only indicated that they would like to continue with e-learning, but also would recommend e-learning to other students. Remarkably, the majority of students would like to see more e-learning offered in their present curricula. They indicated interest in mixed forms of traditional learning and e-learning (“blended learning”, although it is recognized that face-to-face contact between teachers and students is critical. Overall, many students would consider e-learning for further and continuing education after graduation.

  17. U.S. Dental School Applicants and Enrollees: A Ten Year Perspective.

    Science.gov (United States)

    Weaver, Richard G.; Haden, N. Karl; Valachovic, Richard W.

    2000-01-01

    Uses data from the annual American Dental Education Association survey of applicants and enrollees to assess trends over the past 10 years, including the decline in applications beginning in 1998 after several years of increases. Also provides information on quality of applicants, gender, and race/ethnicity. Discusses reasons for the application…

  18. Ten years of Nature Reviews Neuroscience: insights from the highly cited

    NARCIS (Netherlands)

    Luo, L.; Rodriguez, E.; Jerbi, K.; Lachaux, J.P.; Martinerie, J.; Corbetta, M.; Shulman, G.L.; Piomelli, D.; Turrigiano, G.G.; Nelson, S.B.; Joëls, M.; de Kloet, E.R.; Holsboer, F.; Amodio, D.M.; Frith, C.D.; Block, M.L.; Zecca, L.; Hong, J.S.; Dantzer, R.; Kelley, K.W.; Craig, A.D.

    2010-01-01

    To celebrate the first 10 years of Nature Reviews Neuroscience, we invited the authors of the most cited article of each year to look back on the state of their field of research at the time of publication and the impact their article has had, and to discuss the questions that might be answered in

  19. Giant vesical calculus in a ten year-old boy - a case report | Saleh ...

    African Journals Online (AJOL)

    This is a case of longstanding urinary tract symptoms in a 10 year old boy in which multi-modality imaging revealed multiple radio-opaque calculi including a giant vesical calculus. He had surgical removal of the stone with no post-op complications. Keywords: Giant, Vesical Calculus, 10 years old ...

  20. Ten-year literature review of global endometrial ablation with the NovaSure® device

    Directory of Open Access Journals (Sweden)

    Gimpelson RJ

    2014-03-01

    Full Text Available Richard J Gimpelson Mercy Clinic, Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Mercy Hospital St Louis, St Louis, MO, USA Abstract: This review examines the peer-reviewed literature describing prospective studies that report amenorrhea rates, patient satisfaction, and surgical reintervention rates following the NovaSure® endometrial ablation procedure. A search of the English-language literature published from 2000 to 2011 was conducted using PubMed. Ten prospective studies, six single-arm NovaSure trials, and four randomized controlled trials comparing the NovaSure procedure with other global endometrial ablation modalities met the inclusion criteria and were reviewed. The follow-up periods ranged from 6 to 60 months. Amenorrhea rates for the NovaSure procedure ranged from 30.0% to 75.0%. Patients who reported being satisfied with the NovaSure procedure ranged from 85.0% to 94.0%. In randomized controlled trials with other global endometrial ablation modalities, amenorrhea rates at 12 months with the NovaSure procedure ranged from 43.0% to 56.0%, while other modalities ranged from 8% to 24%. In addition, this manuscript reviews the following: the NovaSure technology; use of the NovaSure procedure in the office setting; intraoperative and postoperative pain; effects on premenstrual syndrome (PMS; dysmenorrhea; special circumstances, including presence of uterine disease, history of cesarean delivery, coagulopathy, or use of anticoagulant medication; post-procedure uterine cavity assessment and cancer risk; contraception and pregnancy; and safety. Keywords: abnormal uterine bleeding, menorrhagia, endometrial ablation, NovaSure®

  1. Review of ten-years presence of Aedes albopictus in Spain 2004-2014: known distribution and public health concerns.

    Science.gov (United States)

    Collantes, Francisco; Delacour, Sarah; Alarcón-Elbal, Pedro María; Ruiz-Arrondo, Ignacio; Delgado, Juan Antonio; Torrell-Sorio, Antonio; Bengoa, Mikel; Eritja, Roger; Miranda, Miguel Ángel; Molina, Ricardo; Lucientes, Javier

    2015-12-23

    Ten years have gone by since the Asian tiger mosquito Aedes albopictus was recorded for the first time in Spain. In this paper, all relevant published information about this vector in Spain for the period 2004-2014 is reviewed. The known distribution for 2014 is provided, including all historical records (published and unpublished data) and the results from samplings of the last year. The consequences on public health about the presence of the Asian tiger mosquito in Spain are also highlighted. Further, legal aspects and control plans related to the management and diseases transmitted by this invasive vector species are also discussed.

  2. A ten year Bluebird Trail study at Necedah National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report provides results from a bluebird and tree swallow monitoring study conducted at Necedah National Wildlife Refuge. For the years 1985-1994, nest boxes...

  3. Ten-year climatology of potassium number density at 54° N, 12° E

    Science.gov (United States)

    Lautenbach, J.; Höffner, J.; Lübken, F.-J.; Kopp, M.; Gerding, M.

    2017-09-01

    In the years from 2002 to 2012 potassium densities observations were performed in the mesopause region at Kühlungsborn using a potassium Doppler lidar. The 10-year diurnal data set comprises 5090 h of potassium number densities at 741 days with 25.2% under full daylight conditions. Potassium number densities show a clear semi-annual variation with two broad maxima reoccurring every year. The first maximum occurs in summer and lasts for about 4 months (May-August) with number densities up to 60 atoms/cc. The second maximum is observed from early December to late February with densities up to 30 atoms/cc. Both the peak density and the column density are higher at solstices than at equinoxes. The large data set shows little variation of the mean layer over the 10 years.

  4. A Ten-Year Review of Ovarian Cancer in Enugu, South East Nigeria ...

    African Journals Online (AJOL)

    2000-01-01

    year period at the University of Nigeria Teaching Hospital, Enugu. Methods: A retrospective review of cases of histologically diagnosed primary ovarian cancers from January 1, 2000 to. December 31, 2009. Results: Out of 20,227 gynaecological ...

  5. Ten years of democracy: Translating policy into practice in mathematics and science education

    Directory of Open Access Journals (Sweden)

    Kgabo Masehela

    2005-10-01

    Full Text Available This paper provides a 10-year (1994 – 2004 review of the state of mathematics and physical science education (SME in South Africa with respect to participation and performance, and its relationship with policy implementation.

  6. The ten-thousand year fever: rethinking human and wild primate malarias

    National Research Council Canada - National Science Library

    Cormier, Loretta A

    2011-01-01

    "Malaria is one of the oldest recorded diseases in human history, and its 10,000-year relationship to primates can teach us why it will be one of the most serious threats to humanity in the 21st century...

  7. Ten Years of Forest Cover Change in the Sierra Nevada Detected Using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher S.

    2014-01-01

    A detailed geographic record of recent vegetation regrowth and disturbance patterns in forests of the Sierra Nevada remains a gap that can be filled with remote sensing data. Landsat (TM) imagery was analyzed to detect 10 years of recent changes (between 2000 and 2009) in forest vegetation cover for areas burned by wildfires between years of 1995 to 1999 in the region. Results confirmed the prevalence of regrowing forest vegetation during the period 2000 and 2009 over 17% of the combined burned areas.

  8. Tetanus in a Rural Setting of South-Western Nigeria: a Ten-Year ...

    African Journals Online (AJOL)

    We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level) in Owo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14-70 years (mean 33.25 years, SD ±16.76). The overall case fatality rate (CFR), 32.91%, did was not significantly different in the two ...

  9. Selection and mortality: a ten-year follow-up of income decile mortality in Norway.

    Science.gov (United States)

    Hofoss, Dag; Dahl, Espen; Elstad, Jon Ivar; Cvancarova, Milada

    2013-08-01

    There is universal agreement that higher mortality goes with lower income. Opinions differ on causality: the association may reflect the damaging effect of poverty on health and survival chances. Conversely, it may reflect selection/reverse causation: low income indicates health problems, and from health problems follow a higher risk of dying. We studied all deaths in Norway (111,504) during the 10-year period 1994-2003 among persons aged 25-66 years in 1993 (2,261,076). For each year, age-standardized mortality rates were calculated for each 1993 income decile for men and women separately. Income was calculated as family size-adjusted income after taxes but including cash welfare transfers. If the selection theory was correct, one would expect to see the excess mortality in the lower income fractiles decline as the bad risks, over-represented among the poorer, died away. Large income decile variations in mortality remained at the end of the 10-year period: after 10 years, the age-standardized mortality rate for men and women was still much higher in the lower income deciles. As the excess mortality in the poorer income deciles was not much reduced during the 10-year period, excess mortality among persons in bad health in the lower income deciles does not explain the income inequality in mortality in our data set.

  10. Ten years after the genocide: trauma confrontation and posttraumatic stress in Rwandan adolescents.

    Science.gov (United States)

    Schaal, Susanne; Elbert, Thomas

    2006-02-01

    A decade after the 1994 Rwandan genocide, we interviewed a total of 68 Rwandan orphans about their war experiences and posttraumatic stress disorder (PTSD) symptoms. The two samples comprised youth living either in a child-headed household (CHH) or in an orphanage. All had been exposed to extreme levels of violence and 41% had witnessed the murder of their own mother or father. Of the sample, 44% had PTSD. PTSD vulnerability was greater for youth who at the time of the study lived in CHH than those in an orphanage; it was also higher in those aged 8 to 13 during the outbreak of the genocide than those aged 3 to 7 at the time. Furthermore, a significant relationship was found between the number of traumatic experiences and subsequent stress responses.

  11. Ten years research activities in Earth observation at the Cyprus University of Technology

    Science.gov (United States)

    Hadjimitsis, Diofantos G.; Themistocleous, Kyriacos; Agapiou, Athos; Mamouri, Rodanthi; Nisantzi, Argyro; Papoutsa, Christiana; Tzouvaras, Marios; Neoclous, Kyriacos; Mettas, Christodoulos; Michaelides, Silas

    2017-09-01

    This paper presents the achievements for the last 10 years of the Remote Sensing and Geo-Environment Laboratory of the Cyprus University of Technology in the Earth observation through the ERATOSTHENES Research Centre. Over the past 10 years, the Centre has secured competitive research funding from various sources, such as the European Commission, the Cyprus Research Promotion Foundation, as well as industrial partners, having participated either as a coordinator or as a partner in more than 60 research projects. The research activities of the Centre encompass remote sensing and GIS applications in the fields of Cultural Heritage, Agriculture, Water Resource Management, Environment, Infrastructure, Marine Spatial Planning, Atmospheric, Air Pollution and Coastal Applications, Natural Resource Management and Hazard Assessment. The aim of this paper is to map the existing activities and identify the future trends and goals of the Eratosthenes Research Centre for the next 15 years.

  12. Ten years of tuberculosis intervention in Greenland – has it prevented cases of childhood tuberculosis?

    Directory of Open Access Journals (Sweden)

    Emilie Birch

    2014-07-01

    Full Text Available Background: The incidence of tuberculosis (TB disease in Greenland doubled in the 1990s. To combat the increase, national TB interventions were initiated in 2000 and strengthened in 2007. Objective: To determine whether the effect of interventions could be detected, we estimated the TB disease risk among children≤15 years before and after interventions were implemented. Design: For a study cohort, we recruited all children ≤15 years of age included in the Greenlandic Civil Registration System (CRS from 1990 to 2010. The CRS identifier was used to link cohort participants with TB cases identified based on the Greenlandic National TB registry. Bacille Calmette Guerin (BCG vaccination status was identified through year of birth, as BCG was offered to newborns born either before 1991 or after 1996. Years with interventions were defined as 2000–2006 (primary interventions and 2007–2010 (intensified interventions. Risk of TB was estimated using Poisson regression. Results: The study included 35,858 children, of whom 209 had TB disease. The TB disease incidence decreased after interventions were implemented (2007–2010: IRR [incidence rate ratios] 0.62, 95% CI: 0.39–0.95, p=0.03, compared with the 1995–1999 period. The TB disease risk was inversely associated with BCG vaccination (IRR: 0.54, 95% CI: 0.41–0.72, p<0.001. Conclusions: Years with national TB interventions in Greenland, including neonate BCG vaccination, are associated with a lower TB disease incidence among children ≤15 years of age.

  13. A ten-year study of measles admissions in a Nigerian Teaching ...

    African Journals Online (AJOL)

    Background: Measles remains a major cause of childhood morbidity and mortality in Nigeria despite the availability of safe and effective vaccines. The last report on measles from our center was about 15 years ago. A review of the current status is necessary in order to strengthen interventional strategies. Objectives: To ...

  14. Achieving Collective Impact: Reflections on Ten Years of the University of Georgia Archway Partnership

    Science.gov (United States)

    Garber, Mel; Adams, Katherine R.

    2017-01-01

    Collective impact is a model for achieving tangible change and improvement in communities through a series of well-defined parameters of collaboration. This article provides a 10-year reflection on the University of Georgia Archway Partnership, a university-community collaboration, in the context of the parameters of collective impact. Emphasis is…

  15. A ten-year study of prostate cancer specimens at Ahmadu Bello ...

    African Journals Online (AJOL)

    Objective: To analyze the pattern of distribution of prostate cancer among men in Zaria, Northern Nigeria. Patients and methods: This is a 10-year retrospective histopathological analysis of all prostate cancer cases diagnosed between January 1991 and December 2000 in the Department of Pathology, Ahmadu Bello ...

  16. Moving forward: a review of North-West University's first ten years

    NARCIS (Netherlands)

    van Vught, Franciscus A.; Cloete, Nico; Meek, Lynn; Pityana, Barney; Rasmussen, Torben Kornbech; Singh, Mala; Bunting, Ian

    2014-01-01

    This independent report commissioned by North West University (NWU) contradicts the university's recently published claim that it has bridged its racial divisions and addressed historical inequalities. According to the 10-year review, “Present management structures and practices are not fully

  17. What have we learned from ten years of trajectory research in low back pain?

    DEFF Research Database (Denmark)

    Kongsted, Alice; Kent, Peter; Axén, Iben

    2016-01-01

    Background: Non-specific low back pain (LBP) is often categorised as acute, subacute or chronic by focusing on the duration of the current episode. However, more than twenty years ago this concept was challenged by a recognition that LBP is often an episodic condition. This episodic nature also m...

  18. Alternatives to Custody: A Ten-Year Review of a Community-Based Program in Britain.

    Science.gov (United States)

    Stevens, Barbara Christine

    1996-01-01

    Describes the development of a community forensic psychology service during its first 10 years of service. Service emphasizes cooperation among psychologists, probation officers, and others in establishing alternatives to custody for sex offenders, shoplifters, drug and alcohol abusers, and young criminals. Discusses theoretical orientation of the…

  19. Progression of eye lesions in leprosy: ten-year follow-up study in The Netherlands

    NARCIS (Netherlands)

    Hogeweg, M.; Faber, W. R.

    1991-01-01

    Forty-eight leprosy patients in The Netherlands were re-examined 10 years after initial examination. Forty-six of these patients had received a course of multidrug therapy (MDT), according to the World Health Organization recommendation, at the time of their initial examination. Two patients had

  20. A Ten-Year Follow-Up Study of Deaf-Blind Children.

    Science.gov (United States)

    Curtis, W. Scott; Donlon, Edward T.

    1984-01-01

    A 10-year followup of 49 deaf-blind children provided indirect comparisons of classifications of mental retardation, hearing loss, visual loss, and major communication mode. Results suggested problems with the methodology and indicated the need for new instruments to analyze current functioning as it relates to past evaluation data. (CL)

  1. Ten years of RELEA: Achievements and challenges for astronomy education development

    Science.gov (United States)

    Bretones, P. S.; Jafelice, L. C.; Horvath, J. E.

    2016-10-01

    When an area of education, and more particularly the research within this area, is aimed to development, one of the basic requirements is the existence of a regular publication that accounts for the scientific production in that area. This study aims to analyze 10 years of Latin-American Journal of Astronomy Education (RELEA) [http://www.relea.ufscar.br/].

  2. Ten-Year Trends in Physical Dating Violence Victimization?among?US?Adolescent?Females

    Science.gov (United States)

    Howard, Donna E.; Debnam, Katrina J.; Wang, Min Q.

    2013-01-01

    Background: The study provides 10-year trend data on the psychosocial correlates of physical dating violence (PDV) victimization among females who participated in the national Youth Risk Behavior Surveys of US high school students between 1999 and 2009. Methods: The dependent variable was PDV. Independent variables included 4 dimensions: violence,…

  3. Colorectal cancer in Mauritius: facts and figures -‐ A ten year ...

    African Journals Online (AJOL)

    Among the various types of cancers in Mauritius, colorectal cancer has evolved as 1st in male and 3rd in female in 2008 (National Cancer Action Plan 2010 MOH & QL, Mauritius). Colorectal cancer is one of the leading causes of death worldwide. A retrospective study of 10 years (2001-‐2010) has been carried out using ...

  4. Functional and Anatomic Consequences of Diabetic Pregnancy on Memory in Ten-Year-Old Children.

    Science.gov (United States)

    Jabès, Adeline; Thomas, Kathleen M; Langworthy, Sara; Georgieff, Michael K; Nelson, Charles A

    2015-09-01

    Pregnancies complicated by diabetes mellitus impair offspring memory functions during infancy and early childhood. The purpose of this study was to investigate the long-term consequences of such pregnancies on memory and memory-related brain regions in 10-year-old children. Nineteen children of diabetic mothers (CDMs) and 35 children of nondiabetic mothers participated in this 10-year follow-up study. Memory performance was assessed using a continuous recognition memory task during which children made old/new judgments in response to pictures of concrete and abstract objects presented after different lags or delays. In addition, the volume of the hippocampal formation (HF) was measured using high-resolution structural images. At 10 years of age, recognition memory performance of CDMs did not differ from children of nondiabetic mothers. Similarly, the volume of the HF did not differ between groups. However, the size of the HF in CDMs predicted the time those children needed to provide accurate responses in the continuous recognition memory task. CDMs do not show memory impairments by 10 years of age, despite evidence for such impairments early in life. However, subtle differences in underlying neural processes may still be present. These results have important implications for long-term cognitive development of CDMs.

  5. [A ten-year clinical study of cracked teeth restored with glass ceramic crowns].

    Science.gov (United States)

    Luo, X P; Yuan, Y; Shi, Y J; Qian, D D

    2016-10-09

    Objective: To evaluate the clinic performance of high strength glass ceramic crowns for the painful cracked teeth during a 10-year observation period. Methods: Forty-two posterior teeth from 36 patients were diagnosed as having a crack, biting painful and sensitivity to cold were selected in the Department of Prosthodontic, Institute and Hospital of Stomatology, Nanjing University Medical School. The lost-wax hot pressed glass ceramic crowns were bonded on the minimally invasive prepared teeth by modern adhesive technology. Patients were interviewed and went through clinic examination after one week, one month, and every six months. Results: The effectiveness of 42 glass ceramic crowns for cracked teeth was evaluated for a mean observation time over 10-year. At the first week, 29(81%) patients were free of pain, three still had sensitivity to cold and chewing pain, three still had sensitivity to cold, one had painful to cold and hot. After one month, two patients still had chewing pain, and one tooth needed endodontic treatment after six months. In 10 years, 2(5%) all ceramic crowns were broken, the other 40 restorations kept good clinical performances with a 10-year survival rate of 95%. Conclusions: The high strength glass ceramic crowns are very effective and successful in treating the cracked teeth and then keep the good mastication function and appearance.

  6. Ten-year prevalence of mental disorders in patients presenting with chronic pain in secondary care

    DEFF Research Database (Denmark)

    Søndergård, S; Vaegter, H B; Erlangsen, A

    2018-01-01

    BACKGROUND: Prevalence rates of mental disorders in patients with chronic pain vary and may be overestimated when assessed by screening instruments only. Objectives were to estimate the 10-year prevalence of different mental disorders diagnosed by psychiatrists in patients with chronic pain compa...

  7. Self-Report Stability of Adolescent Cigarette Use across Ten Years of Panel Study Data

    Science.gov (United States)

    Shillington, Audrey M.; Reed, Mark B.; Clapp, John D.

    2010-01-01

    This study is the first to examine adolescent cigarette report stability over 10 years. Six waves of data were utilized from the National Longitudinal Survey of Youth. This study examined internal/logical consistency and external consistency. Report stability was higher for lifetime use reports than the age of onset reports. Wave-by-wave…

  8. Ten Years after the Spellings Commission: From Accountability to Internal Improvement

    Science.gov (United States)

    Liu, Ou Lydia

    2017-01-01

    Student learning outcomes assessment has been increasingly used in U.S. higher education institutions over the last 10 years, partly fueled by the recommendation from the Spellings Commission that institutions need to demonstrate more direct evidence of student learning. To respond to the Commission's call, various accountability initiatives have…

  9. The Gifted Disadvantaged. A Ten Year Longitudinal Study of Compensatory Education in Israel.

    Science.gov (United States)

    Smilansky, Moshe; Nevo, David

    This book reports on compensatory education in Israel and presents results of a 10-year evaluation of the Boarding School Fostering Program, a secondary school project in the education of culturally disadvantaged gifted students. The book is divided into two parts. Part One, "General Orientation to Compensatory Education in Israel," is…

  10. The Development of Writing Habitus: A Ten-Year Case Study of a Young Writer

    Science.gov (United States)

    Compton-Lilly, Catherine

    2014-01-01

    Peter, an African American writer from a low-income community, is followed across a 10-year period as he progresses from first grade through high school. Drawing on writing samples and interviews, the author identifies a set of interrelated dispositions that contribute to his development of "habitus" as a writer. This article considers…

  11. Oregon’s forest resources, 2001–2010: ten-year Forest Inventory and Analysis report

    Science.gov (United States)

    Sheel Bansal; Leslie Brodie; Sharon Stanton; Karen Waddell; Marin Palmer; Glenn Christensen; Olaf Kuegler; John Chase; Joel Thompson; Sarah Jovan; Andrew Gray; Morgan Todd

    2017-01-01

    This report highlights key findings from a comprehensive vegetation survey of all forested land across the state of Oregon. A total of 5,180 forested field plots in Oregon were visited by Forest Inventory and Analysis (FIA) crews over a 10-year period from 2001 to 2010. Oregon has 30 million acres of forest, covering nearly half the state. The structure and composition...

  12. Emotional states in self and others as motives for helping in ten-year-old children

    NARCIS (Netherlands)

    Meerum Terwogt, M.

    2002-01-01

    The participants were 140 children aged 10 years who were asked to imagine themselves as the protagonist in a helping scenario. The first part of the scenario describes an event which is designed to create a happy, angry or emotionally neutral mood state in the protagonist. In the second part the

  13. Ten Years of Change in Sierran Stringer Meadows: An Evaluation of Range Condition Models

    Science.gov (United States)

    Barbara H. Allen

    1989-01-01

    Grazed Sierra Nevada stringer meadow systems were sampled on Blodgett Forest Research Station in northern California between 1977 and 1987 to determine cattle use, and to examine changes in production and species composition over time. Utilization of meadow species averaged 61 percent over the 10 years, but use increased to more than 80 percent utilization after 1985....

  14. Ten Years after the Danish Muhammad Cartoon News Stories: Terror and Radicalization as Predictable Media Events

    DEFF Research Database (Denmark)

    Hervik, Peter

    2018-01-01

    In the tenth year after Danish daily Jyllands-Posten published twelve cartoons, the Muhammad Cartoons, this media event—and the hegemonic understanding behind it—continues to be a discursive reference point for new controversies around national borders and racial boundaries. Then, since late 2010...

  15. Developing Leadership in a Multitype Library Consortium: Ten Years of SEFLIN Sun Seekers

    Science.gov (United States)

    Curry, Elizabeth A.; Smithee, Jeannette

    2009-01-01

    The Southeast Florida Library and Information Network (SEFLIN) has presented the Sun Seeker Leadership Institute biennially since 1997. SEFLIN, a multitype library consortium headquartered in Boca Raton, Florida, was one of the first groups to sponsor a library leadership institute held as a monthly series of events over the period of a year. One…

  16. What have we learnt from the last ten years of ART?

    African Journals Online (AJOL)

    The state programme giving free antiretrovirals. (ARVs) started on 1 April 2004 in several large centres across South Africa. For many of us, it seemed unimaginable, after years of running. HIV battles with President Thabo Mbeki and his odious Minister of Health, 'Manto' Tshabalala-Msimang, on everything from the cause of ...

  17. Geophagia In A Ten-Year-Old African Female With HIV Infection And ...

    African Journals Online (AJOL)

    A very unusual case of geophagia in a 10 year old female patient, with a history of HIV and tuberculosis is reported. While the real prevalence and the pathogenesis of pica are unknown, the associated factors described in this case presentation are multiple. Association between geophagia and HIV or tuberculosis has not ...

  18. Corneal Graft Rejection Ten Years after Penetrating Keratoplasty in the Cornea Donor Study

    Science.gov (United States)

    Dunn, Steven P.; Gal, Robin L.; Kollman, Craig; Raghinaru, Dan; Dontchev, Mariya; Blanton, Christopher L.; Holland, Edward J; Lass, Jonathan H.; Kenyon, Kenneth R.; Mannis, Mark J; Mian, Shahzad I.; Rapuano, Christopher J.; Stark, Walter J.; Beck, Roy W.

    2015-01-01

    Purpose To assess the effect of donor and recipient factors on corneal allograft rejection and evaluate whether a rejection event was associated with graft failure. Methods 1,090 subjects undergoing penetrating keratoplasty for a moderate risk condition (principally Fuchs’ dystrophy or pseudophakic corneal edema) were followed for up to 12 years. Associations of baseline recipient and donor factors with the occurrence of a rejection event were assessed in univariate and multivariate proportional hazards models. Results Among 651 eyes with a surviving graft at 5 years, the 10-year graft failure (± 99% CI) rates were 12% ± 4% among eyes with no rejection events in the first 5 years, 17% ± 12% in eyes with at least one probable, but no definite rejection event, and 22% ± 20% in eyes with at least one definite rejection event. The only baseline factor significantly associated with a higher risk of definite graft rejection was a preoperative history of glaucoma, particularly when prior glaucoma surgery had been performed and glaucoma medications were being used at time of transplant (10-year incidence 35% ± 23% compared with 14% ± 4% in eyes with no history of glaucoma/intraocular pressure treatment, p=0.008). Conclusion Those patients who experienced a definite rejection event frequently went on to graft failure raising important questions as to how we might change acute and long-term corneal graft management. Multivariate analysis indicated that the prior use of glaucoma medications and glaucoma filtering surgery was a significant risk factor related to a definite rejection event. PMID:25119961

  19. Ten-year transient luminous events and Earth observations of FORMOSAT-2

    Science.gov (United States)

    Chern, Rock Jeng-Shing; Lin, Shin-Fa; Wu, An-Ming

    2015-07-01

    The purpose of this paper is to summarize the enormous contributions of FS2 (FORMOSAT-2 or Formosa satellite #2) in both Earth and transient luminous events (TLEs) observations in 10 years. As a small satellite operated for 10 years (20 May 2004 to 20 May 2014) in orbit, FS2 keeps its two unique characteristics: (1) to orbit 14 revolutions around the Earth per day with daily revisit capability, and (2) to provide the capabilities of Earth observation in sunlight time and TLEs observation in eclipsed time every day. It carries two payloads: the remote sensing instrument (RSI) for Earth imaging in satellite's day time and the imager of sprites and upper atmospheric lightning instrument (ISUAL) for scientific observations in satellite's night time, respectively. Daily revisit capability provides changes of events on Earth in either short time (several days) or long term (several years). Examples include: Indian Ocean earthquake and tsunami (December 2004), disintegration of Wilkins Ice Shelf in Antarctica region (2006-2014, long term), Sichuan earthquake (May 2008), Tohoku earthquake and tsunami (March 2011), polar regions (2006-2014, long term), etc. In the TLEs observation, ISUAL had recorded more than 35,000 events in 10 years with 73.93% elves, 6.54% red sprites, 5.81% halos, 13.42% blue jets and 0.30% gigantic jets. Major contributions of FS2 in this specific scientific area are presented. In particular, current and future research topics on TLEs are discussed. Also, major contributions of FS2's RSI to the United Nations Institute for Training and Research (UNITAR) Operational Satellite Applications Programme (UNOSAT) and Group of Earth Observation System of Systems (GEOSS) are summarized. This paper also addresses briefly the health status of FS2 after working 10 years in orbit.

  20. Ten-Year Changes in Healthy Eating Attitudes in the SUN Cohort.

    Science.gov (United States)

    Andrade, Lucia; Zazpe, Itziar; Santiago, Susana; Carlos, Silvia; Bes-Rastrollo, Maira; Martínez-González, Miguel-Angel

    2017-07-01

    The objective of this study was to assess the within-subject longitudinal changes in self-perceived healthy eating attitudes after 10 years of follow-up and to identify predictors of long-term changes in a middle-aged adult cohort. Four thousand five hundred seventy-two participants completed a validated food frequency questionnaire (FFQ) at baseline and after 10 years of follow-up. The FFQ was expanded with a brief 10-item questionnaire about eating attitudes with 2 possible answers: yes or no. A baseline score and a 10-year score were calculated with these 10 items (range from 0 to 10). Participants were categorized into 3 groups according to this score. Linear and logistic regressions were used to examine changes at follow-up and associations between baseline characteristics and improvement in the score. After 10 years of follow-up, a statistically significant favorable change (p < 0.001) was achieved in all questions about eating attitudes, particularly in these items: "Do you try to eat less sweets and pastries?" (12%), "Do you try to eat less meat?" (11.1%), and "Do you try to reduce your fat intake?" (10%). Being female (odds ratio [OR] = 1.19, 95% confidence interval [CI], 1.02-1.39), being 35-50 or ≥ 50 years old (OR = 1.24, 95% CI, 1.07-1.44 and OR = 1.74, 95% CI, 1.38-2.18, respectively), a high level of physical activity (OR for third vs first tertile = 1.20, 95% CI, 1.02-1.41), and a higher Mediterranean diet score (OR for second and third tertiles = 1.18, 95% CI, 1.01-1.37 and OR = 1.26, 95% CI, 1.04-1.52, respectively) were associated with a higher probability of improving the eating attitudes score, while a low body mass index (BMI; OR = 0.71, 95% CI, 0.51-1.00) and snacking between meals (OR = 0.84, 95% CI, 0.73-0.97) were associated with a lower probability of improving their score. The eating attitudes of the participants in the Seguimiento Universidad de Navarra (SUN) cohort became more favorable after 10 years of follow-up. Certain

  1. Ten-year outcomes of monomorphic ventricular tachycardia catheter ablation in repaired tetralogy of Fallot.

    Science.gov (United States)

    Laredo, Mikaël; Frank, Robert; Waintraub, Xavier; Gandjbakhch, Estelle; Iserin, Laurence; Hascoët, Sebastien; Himbert, Caroline; Gallais, Yves; Hidden-Lucet, Françoise; Duthoit, Guillaume

    2017-05-01

    Monomorphic ventricular tachycardia (MVT) is common in adults with repaired tetralogy of Fallot (TOF), and is associated with sudden cardiac death. Management of MVT is not defined, and results of catheter ablation (CA) are limited. To evaluate long-term outcomes of MVT CA in repaired TOF. Thirty-four patients (mean age 32±10.3 years; 59% male) with repaired TOF underwent CA for symptomatic MVT between 1990 and 2012 in our centre; direct-current ablation (DCA) was used in 6%, radiofrequency followed by DCA in 29% and radiofrequency alone in 65%. Right ventricular (RV) dysfunction was present in 35% and left ventricular (LV) dysfunction in 21%. Mean numbers of clinical and induced MVTs were 1 and 2, respectively. Mean VT rate was 225±95bpm. Ablation targeted a single site (range 1-2), which was RV outflow tract in 85%. Primary success, defined as ventricular tachycardia (VT) termination during CA and final non-inducibility, was obtained in 82%. Seven patients (21%) required redo ablation in the first 3 months (before 2004; DCA). No death related to CA occurred. Mean follow-up time was 9.5±5.2 years. Antiarrhythmic therapy was discontinued in 71%. There were two cases of sudden cardiac death and four VT recurrences. Freedom from death and arrhythmia recurrence was 94% at 5 years, 81% at 10 years and 70% at 20 years. Global survival was 91% at 20 years. Baseline LV ejection fraction<60% was significantly associated with ventricular arrhythmia recurrence (hazard ratio 16.4, 95% confidence interval 1.8-147; P=0.01). CA can safely address macroreentrant MVT in repaired TOF patients with an acceptable long-term rate of recurrence in this high-risk population. Anatomical classification of isthmuses with electroanatomical mapping provides reproducible endpoints for CA. Attention should be given to LV systolic function in risk assessment and selection of candidates for implantable cardioverter-defibrillator. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. Tetanus in a Rural Setting of South-Western Nigeria: A Ten-Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    O Adekanle

    2009-01-01

    Full Text Available We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level inOwo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14-70 years(mean 33.25 years, SD ±16.76. The overall case fatality rate (CFR, 32.91%, did was not significantlydifferent in the two hospitals. CFR for men was 32.10% and for women 35.29%. The main factorindicative of bad prognosis was a short hospitalization period. It was observed that 30.38% of ourpatients were discharged against medical advice (DAMA, that financial constraint was the underlyingproblem in 50% of cases, and that the trend of DAMA occurred at the two study sites. This DAMAphenomenon could pose a great danger to the eradication of this vaccine preventable disease in ruralareas.

  3. Rapidly growing cystic vestibular schwannoma with sudden onset facial palsy, ten years after subtotal excision.

    Science.gov (United States)

    Dandinarasaiah, Manjunath; Grinblat, Golda; Prasad, Sampath Chandra; Taibah, Abdelkader; Sanna, Mario

    2017-07-19

    An elderly male patient diagnosed with a right-sided cystic vestibular schwannoma (CVS) at our center underwent a translabyrinthine approach with a subtotal excision to preserve the facial nerve (FN). The tumor grew slowly for the first 9 years but in the subsequent 2 years grew rapidly, with the patient developing a FN paralysis. Using the previous approach, a second surgery was done and the tumor was excised, leaving behind a sheath of tumor on the facial and lower cranial nerves. This case demonstrates that CVSs show unpredictable growth patterns and need to be followed up for a longer period of time. Laryngoscope, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  4. Clinical characteristics and outcomes of critically ill obstetric patients: a ten-year review

    OpenAIRE

    Aldawood, Abdulaziz

    2011-01-01

    BACKGROUND AND OBJECTIVES: Pregnancy and delivery can involve complications that necessitate admission to critical care facilities. The objective of our study was to assess the incidence, indications, and outcomes of obstetric patients requiring admission to an intensive care unit (ICU) in a tertiary care hospital, in Saudi Arabia. DESIGN AND SETTING: Retrospective cohort study of consecutive obstetric admissions to the ICU at the King Abdulaziz Medical City over a 10-year period. PATIENTS AN...

  5. 436 Ten Years Follow up of Japanese Survey on Immediate Type Food Allergy

    OpenAIRE

    Imai, Takanori; Sugizaki, Chizuko; Ebisawa, Motohiro

    2012-01-01

    Background The food labeling system for food allergens was introduced from April 2002 in Japan. To confirm the effectiveness of the system, we regularly conduct a nationwide food allergy survey every 3 years. Methods The survey was conducted in cooperation with over 1000 volunteer doctors in Japan at 2001+2002, 2005 and 2008. We have sent questionnaires to contributing doctors every 3 months based on the previous survey system, and contributing doctors were asked to report immediate type food...

  6. Ten Years Risk Prediction of a Major Cardiovascular Event in a Rural Block in Tamil Nadu

    Directory of Open Access Journals (Sweden)

    Logaraj Muthunarayanan

    2015-01-01

    Full Text Available Background: India has a high burden of cardiovascular diseases (CVDs. High-risk interventions can be initiated only when individuals at high-risk have been identified. Objectives: The objective was to estimate the prevalence and the sociodemographic pattern of cardiovascular risk factors and to predict the 10 years risk of fatal and nonfatal major cardiovascular events in a rural population in Tamil Nadu. Materials and Methods: A cross-sectional study was conducted among 30 villages of a rural block in Tamil Nadu from March 2012 to February 2013 in the age group of 40-79 years attending our fixed mobile clinics using structured interview schedule and subsequently, the World Health Organization/International Society of Hypertension (WHO/ISH risk charts were used to predict the 10 years absolute risk of fatal or nonfatal cardiovascular event. Results: A total of 482 individuals were studied of which 68.3% were women and 31.7% were men. Prevalence of overweight, diabetes, and systolic hypertension was found to be 60%, 22.8%, and 34.6%, respectively. A majority (79.9% of the study population had 10 years cardiovascular risk of <10% while only 2.5% had a risk of more than 40%. As the age advances, the proportion of participants with high-risk also increased and this trend was statistically significant (P = 0.001. Conclusion: Less than 10% of the population had a high-risk of CVD based on WHO/ISH risk score. These charts help identify the high-risk groups in the population in resource-scarce setting and thus an appropriate action can be taken.

  7. Tumors of the liver; a ten year study in Children Medical Center

    Directory of Open Access Journals (Sweden)

    Farahmand F

    2007-06-01

    Full Text Available Background: The aim of this study was to review the frequency, histopathology and outcome in children with tumors of the liver. Methods: Included in this retrospective/descriptive study were 30 children treated for liver tumors from 1375-1384 (ca. 1996-2005, at Children’s Hospital Medical Center, Tehran, Iran. We included the clinical, radiologic, and pathologic data of our patients, focusing on the frequency, etiology and outcome. Results: Patient ages ranged from three months to 12 years (median 3.8 years, with 18 males (60% and 12 females (40%. Of these, 17 patients had hepatoblastoma (55.66%, including 13 males and four females, with an age range of six months to five years. Four cases (13.33% had neuroblastoma. Hepatocellular carcinoma (HCC was found in three cases (10%, all of whom were carriers of hepatitis B. Two cases (6.66% were diagnosed with mesenchymal hamartoma, two cases (6.66% with hemangioendothelioma and two cases (6.66% with rhabdomyosarcoma and leiomyosarcoma of the biliary tract. Abdominal swelling and hepatomegaly were seen in all of patients. Jaundice was observed in two cases. Serum alpha-fetoprotein levels greater than 500 ng/ml were seen in 17 cases (56.66%. All patients were receiving specific treatment. The three-year survival rate was 65% for hepatoblastoma and 2% for HCC Conclusion: With the introduction of specific treatment, the survival rate for children with tumors of the liver has significantly increased. Further improvement can be achieved using diagnostic biopsy for hepatoblastoma, although it may result in complications, and preoperative chemotherapy followed by complete surgical excision (per International Society of Pediatric Oncology guidelines, yielding an outstanding survival rate of 80%.

  8. Ten-year audit of Lichtenstein hernioplasty under local anaesthesia performed by surgical residents

    Directory of Open Access Journals (Sweden)

    Paajanen Hannu

    2010-08-01

    Full Text Available Abstract Background To analyse in a prospective trial the long-term results of Lichtenstein hernioplasty performed by surgical trainees. Methods Training of tension-free Lichtenstein hernia operation was started in our ambulatory unit as an outpatient procedure under local anaesthesia in 1996. After performing 36 teaching operations together with residents and their supervising specialist, 281 patients were operated during 1996-2000 either by one senior consultant (n = 141 or by 12 surgical trainees (n = 140. After 10 years, 247 (88% patients were available for the long-term assessment. Results After one month postoperatively, the rate of wound infections (consultant 1.1%, residents 0.7% and hematomas (consultant 1.1%, residents 3.0% were low and not related to surgeon's training level (ns. Only 6 (2.1% clinically evident recurrences were found after 10 years: two after specialist repair and four after trainee repair (ns. Although one third of the patients reported some discomfort after 3 and 10 years, 93-95% of the patients were very satisfied with the operation, with no statistical difference between the surgeons. Conclusion Ambulatory open mesh repair under local anaesthesia was a safe operation and the long-term results were acceptable among the patients operated by surgical trainees.

  9. Ten-year audit of Lichtenstein hernioplasty under local anaesthesia performed by surgical residents.

    Science.gov (United States)

    Paajanen, Hannu; Varjo, Riitta

    2010-08-04

    To analyse in a prospective trial the long-term results of Lichtenstein hernioplasty performed by surgical trainees. Training of tension-free Lichtenstein hernia operation was started in our ambulatory unit as an outpatient procedure under local anaesthesia in 1996. After performing 36 teaching operations together with residents and their supervising specialist, 281 patients were operated during 1996-2000 either by one senior consultant (n = 141) or by 12 surgical trainees (n = 140). After 10 years, 247 (88%) patients were available for the long-term assessment. After one month postoperatively, the rate of wound infections (consultant 1.1%, residents 0.7%) and hematomas (consultant 1.1%, residents 3.0%) were low and not related to surgeon's training level (ns). Only 6 (2.1%) clinically evident recurrences were found after 10 years: two after specialist repair and four after trainee repair (ns). Although one third of the patients reported some discomfort after 3 and 10 years, 93-95% of the patients were very satisfied with the operation, with no statistical difference between the surgeons. Ambulatory open mesh repair under local anaesthesia was a safe operation and the long-term results were acceptable among the patients operated by surgical trainees.

  10. SPIN-UP Ten Years Later: What's Still Solid and What's New

    Science.gov (United States)

    Howes, Ruth

    2010-02-01

    Seven years ago, the SPIN-UP Report produced by the National Task Force on Undergraduate Physics identified several key characteristics of undergraduate physics programs that were thriving amid a general decline in the numbers of physics majors. Since that time, the number of physics majors graduating has increased each year. Nevertheless, the rate of growth has slowed in the last several years, and many departments are threatened in the current financial crisis because of low undergraduate enrollments. All undergraduate programs face challenges of the growing use of computation in physics, the pressure from administrators and funding agencies to participate in interdisciplinary work, the lack of gender and ethnic diversity in physics, and changes in students' math preparation as well as the standard issues of large service enrollments and scarcity of resources. Therefore, this is an appropriate time to revisit the conclusions of the SPIN-UP report and consider its recommendations and new ideas to continue the growth of robust undergraduate physics programs. )

  11. Ten years of the Immune Tolerance Network: an integrated clinical research organization.

    Science.gov (United States)

    Bluestone, Jeffrey A; Krensky, Alan M; Turka, Laurence A; Rotrosen, Daniel; Matthews, Jeffrey B

    2010-02-17

    The U.S. National Institutes of Health Roadmap and the U.S. Food and Drug Administration's Critical Path Initiative have endorsed the establishment of large academic clinical research networks as part of the solution to the growing divide between increased R&D spending and the lagging number of new drugs making it to market. Clearly, the role of these networks as translational science incubators that complement industry-sponsored programs is laudable and much-needed. However, the path to success for such organizations is less clear. Here, drawing on the experiences of the Immune Tolerance Network, a multidisciplinary clinical research network founded in 1999, we discuss some of the barriers inherent in developing such consortia and offer firsthand insight into the planning, resources, and organizational infrastructure required for a successful research program.

  12. An overview of ten years of student research and JDSO publications

    Science.gov (United States)

    Freed, Rachel; Fitzgerald, Michael; Genet, Russell; Davidson, Brendan

    2017-06-01

    The astronomy research seminar, initially designed and taught by Russell Genet at Cuesta College over the past decade, has resulted in over 100 published student research papers in the Journal of Double Star Observations along with dozens of other papers and conference presentations. While the seminar began at a single community college it has now spread to include students from dozens of institutions and instructors, reaching students from middle school through graduate school. The seminar has integrated the large community-of-practice of amateur and professional astronomers, educators, students, and hardware and software engineers while providing an important experience for student researchers. In this paper, we provide an overview analysis of 109 publications authored by 320 individual students involved in the astronomy research seminar over the last decade.

  13. An Overview of Ten Years of Student Research and JDSO Publications (Abstract)

    Science.gov (United States)

    Freed, R.; Fitzgerald, M.; Genet, R.; Davidson, B.

    2017-12-01

    (Abstract only) The astronomy research seminar, initially designed and taught by Russell Genet at Cuesta College over the past decade, has resulted in over 100 published student research papers in the Journal of Double Star Observations along with dozens of other papers and conference presentations. While the seminar began at a single community college, it has now spread to include students from dozens of institutions and instructors, reaching students from middle school through graduate school. The seminar has integrated the large community-of-practice of amateur and professional astronomers, educators, students, and hardware and software engineers while providing an important experience for student researchers. In this paper, we provide an overview analysis of 109 publications authored by 320 individual students involved in the astronomy research seminar over the last decade.

  14. Educational virtual environments: A ten-year review of empirical research (1999-2009)

    DEFF Research Database (Denmark)

    Mikropoulos, Tassos; Natsis, Antonios

    2011-01-01

    value of VR and incorporate their learning goals in Educational Virtual Environments (EVEs). Although VR supports multisensory interaction channels, visual representations predominate. Few are the studies that incorporate intuitive interactivity, indicating a research trend in this direction. Few...... are the settings that use immersive EVEs reporting positive results on users’ attitudes and learning outcomes, indicating that there is a need for further research on the capabilities of such systems. Features of VR that contribute to learning such as first order experiences, natural semantics, size, transduction......, reification, autonomy and presence are exploited according to the educational context and content. Presence seems to play an important role in learning and it is a subject needing further and intensive studies. Constructivism seems to be the theoretical model the majority of the EVEs are based on. The studies...

  15. Childhood diabetes mellitus in sokoto, north-western Nigeria: A ten year review

    Directory of Open Access Journals (Sweden)

    Omoshalewa Ugege

    2013-01-01

    Full Text Available Background : There is paucity of literature on childhood diabetes mellitus (DM from developing countries, especially North-Western Nigeria. We describe the clinical presentation and outcome of childhood DM as seen in Usmanu Danfodiyo University Teaching Hospital (UDUTH Sokoto, Nigeria. Materials and Methods : This was a 10-year retrospective review of case files of children aged 15 years and below with childhood DM seen between September 1 st 2001 and August 31 st 2011. The age, gender, presenting features, complications, laboratory features, and outcome of the patients were extracted and analyzed. Results: Eight out of the 23,931 children admitted during the study period were diagnosed with type 1 (T1 DM, giving a case prevalence rate of 0.33/1000 (3/10 000. The male-to-female ratio was 1:1. The mean age at presentation was 11.8 ± 3.1 years. The mean duration of symptoms before presentation was 6 ± 4.9 weeks (range 1.2-12 weeks. The most prevalent symptoms were polyuria and weight loss, 7 (87.5% each, polydipsia, 6 (75%, polyphagia, 5 (62.5%, and weakness, 4 (50%. Five (62.5% patients presented with diabetes ketoacidosis (DKA. The mean random blood sugar (RBS was 22.6 ± 12.01 (range 13-49.5 mmol/L. Five (62.5% patients were discharged while three (37.2% left against medical advice. Four (80% of the discharges were lost to follow up. Conclusion: Childhood DM is relatively uncommon in UDUTH, Sokoto. There is a high frequency of DKA, late presentation, and default to follow up. We recommend increased awareness campaigns and health education on childhood DM.

  16. Ten-year incidence of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi-seropositive former blood donors.

    Science.gov (United States)

    Sabino, Ester C; Ribeiro, Antonio L; Salemi, Vera M C; Di Lorenzo Oliveira, Claudia; Antunes, Andre P; Menezes, Marcia M; Ianni, Barbara M; Nastari, Luciano; Fernandes, Fabio; Patavino, Giuseppina M; Sachdev, Vandana; Capuani, Ligia; de Almeida-Neto, Cesar; Carrick, Danielle M; Wright, David; Kavounis, Katherine; Goncalez, Thelma T; Carneiro-Proietti, Anna Barbara; Custer, Brian; Busch, Michael P; Murphy, Edward L

    2013-03-12

    Very few studies have measured disease penetrance and prognostic factors of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi-infected persons. We performed a retrospective cohort study among initially healthy blood donors with an index T cruzi-seropositive donation and age-, sex-, and period-matched seronegatives in 1996 to 2002 in the Brazilian cities of São Paulo and Montes Claros. In 2008 to 2010, all subjects underwent medical history, physical examination, ECGs, and echocardiograms. ECG and echocardiogram results were classified by blinded core laboratories, and records with abnormal results were reviewed by a blinded panel of 3 cardiologists who adjudicated the outcome of Chagas cardiomyopathy. Associations with Chagas cardiomyopathy were tested with multivariate logistic regression. Mean follow-up time between index donation and outcome assessment was 10.5 years for the seropositives and 11.1 years for the seronegatives. Among 499 T cruzi seropositives, 120 (24%) had definite Chagas cardiomyopathy, and among 488 T cruzi seronegatives, 24 (5%) had cardiomyopathy, for an incidence difference of 1.85 per 100 person-years attributable to T cruzi infection. Of the 120 seropositives classified as having Chagas cardiomyopathy, only 31 (26%) presented with ejection fraction <50%, and only 11 (9%) were classified as New York Heart Association class II or higher. Chagas cardiomyopathy was associated (P<0.01) with male sex, a history of abnormal ECG, and the presence of an S3 heart sound. There is a substantial annual incidence of Chagas cardiomyopathy among initially asymptomatic T cruzi-seropositive blood donors, although disease was mild at diagnosis.

  17. Ten-Year Incidence of Chagas Cardiomyopathy Among Asymptomatic Trypanosoma cruzi–Seropositive Former Blood Donors

    Science.gov (United States)

    Sabino, Ester C.; Ribeiro, Antonio L.; Salemi, Vera M.C.; Di Lorenzo Oliveira, Claudio; Antunes, Andre P.; Menezes, Marcia M.; Ianni, Barbara M.; Nastari, Luciano; Fernandes, Fabio; Patavino, Giuseppina M.; Sachdev, Vandana; Capuani, Ligia; de Almeida-Neto, Cesar; Carrick, Danielle M.; Wright, David; Kavounis, Katherine; Goncalez, Thelma T.; Carneiro-Proietti, Anna Barbara; Custer, Brian; Busch, Michael P.; Murphy, Edward L.

    2013-01-01

    Background Very few studies have measured disease penetrance and prognostic factors of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi–infected persons. Methods and Results We performed a retrospective cohort study among initially healthy blood donors with an index T cruzi–seropositive donation and age-, sex-, and period-matched seronegatives in 1996 to 2002 in the Brazilian cities of São Paulo and Montes Claros. In 2008 to 2010, all subjects underwent medical history, physical examination, ECGs, and echocardiograms. ECG and echocardiogram results were classified by blinded core laboratories, and records with abnormal results were reviewed by a blinded panel of 3 cardiologists who adjudicated the outcome of Chagas cardiomyopathy. Associations with Chagas cardiomyopathy were tested with multivariate logistic regression. Mean follow-up time between index donation and outcome assessment was 10.5 years for the seropositives and 11.1 years for the seronegatives. Among 499 T cruzi seropositives, 120 (24%) had definite Chagas cardiomyopathy, and among 488 T cruzi seronegatives, 24 (5%) had cardiomyopathy, for an incidence difference of 1.85 per 100 person-years attributable to T cruzi infection. Of the 120 seropositives classified as having Chagas cardiomyopathy, only 31 (26%) presented with ejection fraction <50%, and only 11 (9%) were classified as New York Heart Association class II or higher. Chagas cardiomyopathy was associated (P<0.01) with male sex, a history of abnormal ECG, and the presence of an S3 heart sound. Conclusions There is a substantial annual incidence of Chagas cardiomyopathy among initially asymptomatic T cruzi–seropositive blood donors, although disease was mild at diagnosis. PMID:23393012

  18. Ten-year survival and success rate of implant-prosthodontic treatment

    Directory of Open Access Journals (Sweden)

    Nataša Ihan Hren

    2013-12-01

    Full Text Available Introduction: Implant-prosthodontic treatment for restoring a single missing tooth, partial edentulism and complete edentulism is a predictive and successful method in terms of both the survival rate of implants and the different parameters which determine the success rate of the treatment. The purpose of this study was to evaluate the 10-year survival and success rates of dental implants, analyze the causes of early and late complications, and assess the type and number of prosthodontic complications.Patients and methods: In 51 patients, 113 titanium dental implants were inserted by one surgeon using a two-stage surgical protocol. The prosthodontic treatment included fixed or removable treatment options. Implant survival and success were evaluated 10 years after the completion of prosthodontic treatment. The evaluation comprised history, clinical examination with assessment of success parameters (prosthesis functionality, peri-implant tissue status, and x-ray assessment of bone loss.Results: Two implants were lost before and two 10 years after the prosthodontic treatment. The survival rate of implants was 96.4 % on the average, 100 % in the lower jaw, and 92.5 % in the upper jaw. Peri-implantitis was diagnosed in 4.5 % of all implants. The success rate was thus 95.5 %. Technical complications occurred in 2.8 % of fixed prostheses and 19 % of removable prostheses.Conclusion: The long-term survival and success rates of dental implants are high. Proper implant prosthodontic treatment planning is crucial to achieving high survival and success rates of implant treatment. Bone quality has to be taken into account when implant treatment is performed. Peri-implantitis is rarely observed, and prosthodontic complications are uncommon. On completion of the surgical and prosthetic phases of treatment, patients must be followed at regular intervals to ensure timely management of complications.

  19. Academic achievement in children ten to 12 years after Haemophilus influenzae meningitis.

    Science.gov (United States)

    Feldman, H M; Michaels, R H

    1988-03-01

    Academic achievement by 23 children 10 to 12 years after treatment of Haemophilus influenzae meningitis was assessed using individually administered standardized tests, review of school transcripts, and parent and teacher questionnaires. The children's performance was compared with (1) their own performance in a previous study 6 to 8 years after the illness; (2) the performance of 23 similarly aged siblings in the previous study, a comparison which served to age match subjects and sibling controls; and (3) the performance of 11 of those similarly aged siblings retested in the current study. Subjects scored in the average range on all measures. Scores were comparable to results 4 years previous in four of six academic measures, with minor deterioration in reading single words and decoding nonsense words. There were no differences between subjects in the current study and control subjects from the previous study, except in decoding nonsense words, and no differences between subjects and control subjects in the current study, except in paragraph reading accuracy. Scholastic grade point averages and scores on parent and teacher behavior problem-rating scales showed no group differences. Subjects used more school-based remedial services, although the trend did not achieve statistical significance. Parents reported spending more time with subjects than with control subjects helping with homework. These findings suggest that children who have recovered from meningitis due to H influenzae can maintain scores and grades comparable to their siblings as they progress to middle school. Their academic success may involve more school and family support to compensate for the mild differences in intelligence quotient and neuropsychologic testing found in the previous study.

  20. Ten-year epidemiology of chemical burns in western Zhejiang Province, China.

    Science.gov (United States)

    Ye, Chunjiang; Wang, Xingang; Zhang, Yuanhai; Ni, Liangfang; Jiang, Ruiming; Liu, Liping; Han, Chunmao

    2016-05-01

    Chemical burns occur frequently in western Zhejiang Province. This study documents the epidemiology of chemical burns in the region using burn data from a local specialized hospital. Results from this analysis will assist in the planning of prevention strategies for high-risk occupations and groups. A 10-year retrospective analysis was conducted for all patients with chemical burns admitted to the Department of Burn and Plastic Surgery from January 2004 to December 2013. Information obtained for each patient included demographics (gender, age, occupation and education), location of the burn, cause of the burn, and categories of chemicals. Data regarding the season of admittance, prehospital treatment, wound site/size (area, region, and depth), accompanying injuries, operations, length of hospital stay and mortality were also assessed. A total of 690 patients (619 males, 71 females; average age: 30.6±12.4 years) were admitted to the department for chemical burns. Over the 10-year period, the incidence of chemical burns showed an increasing tendency. Chemical burns occurred most frequently in patients aged 20-59 years (94.79%). Most of the chemical burns were work-related, primarily in private enterprises (47.97%) and state-owned enterprises (24.93%). Operations (68.99%) and machine problems (17.26%) were the main causes of chemical burns in the workplace. With regard to burns caused by chemicals, most were caused by acids (72.01%), with hydrofluoric acid and sulphuric acid causing 51.45%. Most chemical burns occurred in the summer and autumn seasons (61.02%). The burn size was burns covering >40% TBSA. The most common burn sites were the upper extremities (31.57%), lower extremities (19.86%), and head and neck (28.83%). Most patients (581 (84.20%)) received water washing treatment on site immediately after exposure. The most common accompanying injuries included inhalation injury, ocular burns and digestive tract injury. The average hospital stay was 17.0±23

  1. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    Science.gov (United States)

    Pearson, Scott F; Giovanini, Jack; Jones, Jay E; Kroll, Andrew J

    2015-01-01

    Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years) and long-term (~10 years) avian community responses (occupancy and abundance) to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m) forested buffers on each side of the stream, and sites with wider (~30 m) and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74%) relative to the controls (29%). We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals) for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29%) and Wide buffers (short-term: 21%; long-term 93%) relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that range from

  2. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    Directory of Open Access Journals (Sweden)

    Scott F Pearson

    Full Text Available Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years and long-term (~10 years avian community responses (occupancy and abundance to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m forested buffers on each side of the stream, and sites with wider (~30 m and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74% relative to the controls (29%. We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29% and Wide buffers (short-term: 21%; long-term 93% relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that

  3. Ten years of flight service with DC-10 composite rudders - A backward glance

    Science.gov (United States)

    Hawley, Arthur V.

    1986-01-01

    Carbon-epoxy upper aft rudders have been successfully evaluated on the DC-10 during 10 years of airline flight service. They have flown for more than 320,000 flight hours, with 36,000 flight hours flown by a single rudder. The rudder box is of thin-skin buckled construction and is cocured out-of-autoclave as a one-piece assembly. Weight saving can exceed the rudder weight if full advantage is taken of removing balance weight from the forward rudder.

  4. Trends in types of dermatology books available over the last ten years.

    Science.gov (United States)

    Aquino, Lisa L; Wu, Jashin J

    2009-06-15

    Shifts in interest toward cosmetic and surgical dermatology and away from medical and academic dermatology have been observed in recent years. We hypothesized that this trend would be evident in the types of books available for purchase from a major medical textbook supplier. Books published from 1998-2008 were categorized by type and statistical testing was performed to determine if this trend has been reflected in books published. The percentage of medical dermatology books decreased over time, whereas the percentage of cosmetic and surgical dermatology books increased over time.

  5. Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

    Science.gov (United States)

    Milad, Mohammed R.; Quirk, Gregory J.

    2016-01-01

    The psychology of extinction has been studied for decades. Approximately 10 years ago, however, there began a concerted effort to understand the neural circuits of extinction of fear conditioning, in both animals and humans. Progress during this period has been facilitated by an unusual degree of coordination between rodent and human researchers examining fear extinction. This successful research program could serve as a model for translational research in other areas of behavioral neuroscience. Here we review the major advances and highlight new approaches to understanding and exploiting fear extinction. PMID:22129456

  6. Ten Years of MISR Observations from Terra: Looking Back, Ahead, and in Between

    Science.gov (United States)

    Diner, David J.; Ackerman, Thomas P.; Braverman, Amy J.; Bruegge, Carol J.; Chopping, Mark J.; Clothiaux, Eugene E.; Davies, Roger; Di Girolamo, Larry; Kahn, Ralph A.; Knyazikhin, Yuri; hide

    2010-01-01

    The Multi-angle Imaging SpectroRadiometer (MISR) instrument has been collecting global Earth data from NASA's Terra satellite since February 2000. With its nine along-track view angles, four visible/near-infrared spectral bands, intrinsic spatial resolution of 275 m, and stable radiometric and geometric calibration, no instrument that combines MISR's attributes has previously flown in space. The more than 10-year (and counting) MISR data record provides unprecedented opportunities for characterizing long-term trends in aerosol, cloud, and surface properties, and includes 3-D textural information conventionally thought to be accessible only to active sensors.

  7. Ten-year epidemiological study of chemical burns in Jinshan, Shanghai, PR China.

    Science.gov (United States)

    Li, Wei; Wu, Xiaofeng; Gao, Chengjin

    2013-11-01

    The epidemiological pattern of chemical burns varies widely in different areas of the world. To analyse effective preventive approaches, an insight into the pattern of injury is desirable. However, our data are only limited to Shanghai area, China. A 10-year retrospective review includes all patients with chemical burns admitted to the Department of Burn and Plastic Surgery from January 2001 to December 2010; those who were admitted to the ophthalmologic department or other departments were excluded. The data collected included age, gender, injury pattern, patient workplaces, aetiological agents, incidence by month and year, burn size, burn depth and site, time for immediate irrigation, length of hospital stay and outcome. A total of 615 patients admitted to our department for in-hospital treatment of chemical burn injury were included in the study. The mean age was 32.1±12.3 years with a range of 2-66 years. A total of 562 cases (91.4%) were male and 53 cases (8.6%) female. The mean total burn surface area (TBSA) was 30.3±24.7% with a mean full-thickness burn area of 17.5±23.8%. Most chemical burns took place in summer and fall. The majority of chemical burns were work related (93.0%); among them accidents that happened in private factories were predominant (70.8%). Although caustic soda was the leading cause of all chemical burns (15.8%), acid burn was the most common (45.2%). The extremities were the most frequent areas of injuries, followed by head and neck. Most cases had none (30.4%) or insufficient (61.1%) immediate irrigation after injury. In all patients, 47 cases had inhalation injuries, 94 cases accompanying ophthalmologic burns, 51 cases accompanying other associated injuries and 67 cases chemical toxicity. A total of 212 cases (34.5%) underwent early total or tangential excision and skin or skin flap grafting in the first week after injury. The mean length of hospital stay was 44.1±24.7 days. Sixteen cases died of respiratory failure, sepsis or

  8. Clinical accuracy ratings of MMPI approaches for adolescents: adding ten years and the MMPI-A.

    Science.gov (United States)

    Janus, M D; Tolbert, H; Calestro, K; Toepfer, S

    1996-10-01

    Ehrenworth and Archer (1985) examined the relative merits of adolescent Minnesota Multiphasic Personality Inventory (MMPI) profiles utilizing either adult or adolescent scoring norms (Marks & Briggs, 1972). Eleven years later, the MMPI-A has been introduced into clinical use. It has been suggested that in these early years of the MMPI-A, clinicians plot both MMPI-A norms and Marks and Briggs (1972) norms to derive a clinical interpretation of a given profile, especially when code type interpretation is used (Archer, 1992). This study partially replicates the work of Ehrenworth and Archer (1985) by exploring the relation between code types generated with different norms (MMPI-A [Marks & Briggs, 1972] and adult K-corrected) in a sample of 134 adolescent psychiatric inpatients (77 female, 57 male). Code type narratives were blindly rated by members of the adolescent inpatient treatment staff. Although mean scores for the MMPI-A were significantly lower than those produced by the other two sets of norms, the use of the MMPI-A did not result in a clinical disadvantage. Both sets of adolescent norms (the Marks & Briggs and the MMPI-A) produced higher accuracy ratings than did the use of adult K-corrected norms but did not differ from each other. Gender differences were found on all three sets of norms, with female adolescent psychiatric inpatients scoring higher than male inpatients, particularly on Scales 1, 2, and 3.

  9. Systemic lupus erythematosus pregnancies: ten-year data from a single centre in Malaysia.

    Science.gov (United States)

    Teh, C L; Wan, S A; Cheong, Y K; Ling, G R

    2016-08-13

    We performed a retrospective study of all systemic lupus erythematosus (SLE) pregnancies during a 10-year period (2006-2015) to describe the clinical features, maternal and foetal outcomes in our centre. There were 115 pregnancies in 86 women with SLE. Our patients had a mean age of 29.1 years (SD 5.80) and a mean disease duration of 44.63 months (SD 41.17). Fifteen patients had antiphospholipid syndrome (APS). Our patients had complicated pregnancies: 26.1% had SLE flares, 13.9% had pre-eclampsia and 45.1% needed caesarean sections. There were 23.3% foetal losses and 25% preterm deliveries in our patients. There was a higher rate of unplanned pregnancies and lupus flare among pregnancies with active SLE at conception. Pregnancies in lupus nephritis have higher incidence of lupus flares during pregnancy but similar maternal and foetal outcomes compared to those without nephritis. The prognostic indicators for adverse foetal outcome in our patients were flare of SLE (HR 4.08 [CI 95% 1.65-10.13, p < 0.01]) and APS (HR 3.07 [CI 95% 1.12-8.42, p < 0.05]) and the prognostic indicator for adverse maternal outcome was hypertension (HR 3.58 [CI 95% 1.30-9.90, p < 0.05]). Lupus pregnancies in our centre remained as high-risk pregnancies with significant maternal and foetal complications. © The Author(s) 2016.

  10. Ego-resiliency development from late adolescence to emerging adulthood: A ten-year longitudinal study.

    Science.gov (United States)

    Alessandri, Guido; Eisenberg, Nancy; Vecchione, Michele; Caprara, Gian Vittorio; Milioni, Michela

    2016-07-01

    This study examined the development of ego-resiliency from late adolescence to emerging adulthood, using a 10-year cohort-sequential design. Participants were 335 Italian adolescents (173 females and 162 males), living, at the time of the study, in Genzano, a small city near to Rome. Latent growth curve analyses indicated that the developmental trajectory of ego-resiliency from 15 to 25 years is adequately described by a piecewise model that included separate growth profiles corresponding to different developmental stages. Essentially, ego-resiliency remained remarkably stable until the end of high school, and then encountered a phase of relative increase. Moreover, the trajectory of ego-resiliency from ages 15 to 19 was predicted by self-efficacy beliefs in managing negative emotions, and the trajectory from age 19 to 25 was predicted by experienced familial support and self-efficacy beliefs in expressing positive emotions at age 15. Experienced stressful life events also accounted for individuals' deviation from the typical ego-resiliency trajectory. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  11. How to identify randomized controlled trials in MEDLINE: ten years on*

    Science.gov (United States)

    Glanville, Julie M.; Lefebvre, Carol; Miles, Jeremy N. V.; Camosso-Stefinovic, Janette

    2006-01-01

    Objective: The researchers sought to assess whether the widely used 1994 Cochrane Highly Sensitive Search Strategy (HSSS) for randomized controlled trials (RCTs) in MEDLINE could be improved in terms of sensitivity, precision, or parsimony. Methods: A gold standard of 1,347 RCT records and a comparison group of 2,400 non-trials were randomly selected from MEDLINE. Terms occurring in at least 1% of RCT records were identified. Fifty percent of the RCT and comparison group records were randomly selected, and the ability of the terms to discriminate RCTs from non-trial records was determined using logistic regression. The best performing combinations of terms were tested on the remaining records and in MEDLINE. Results: The best discriminating term was “Clinical Trial” (Publication Type). In years where the Cochrane assessment of MEDLINE records had taken place, the strategies identified few additional unindexed records of trials. In years where Cochrane assessment has yet to take place, “Randomized Controlled Trial” (Publication Type) proved highly sensitive and precise. Adding six more search terms identified further, unindexed trials at reasonable levels of precision and with sensitivity almost equal to the Cochrane HSSS. Conclusions: Most reports of RCTs in MEDLINE can now be identified easily using “Randomized Controlled Trial” (Publication Type). More sensitive searches can be achieved by a brief strategy, the Centre for Reviews and Dissemination/Cochrane Highly Sensitive Search Strategy (2005 revision). PMID:16636704

  12. [Ten-years records of organic arsenic (diphenylarsinic acid) poisoning: epidemiology, clinical feature, metabolism, and toxicity].

    Science.gov (United States)

    Ishi, Kazuhiro; Tamaoka, Akira

    2015-01-01

    We report here the symptoms of diphenylarsinic acid (DPAA) poisoning recorded over 10 years since the DPAA contamination of the potable well water was first detected in the Kamisu City, Ibaraki Prefecture, in 2003. The poisoning symptoms associated with the cerebellum and brainstem included nystagmus, tremors, myoclonus, and cerebellar ataxia as well as the symptoms associated with the temporal and occipital lobes such as memory impairment, sleep disorder, and visual disturbance. Some of the affected children exhibited mental retardation. Moreover, reduced blood flow and reduced glucose metabolism in the cerebella, brainstem, and temporal and occipital lobes persisted for several years among the DPAA-exposed persons. Based on the animal studies for DPAA intoxication, the target organs for the DPAA toxicity were determined to be the central nervous system (CNS), liver, and biliary system. In particular, DPAA tends to persist in the brain for a long time, resulting in long-term impacts on the brain. The cerebral blood flow and brain glucose metabolism, which can be measured by positron emission tomography (PET) and single photon emission computed tomography (SPECT), respectively, are useful objective clinical markers to determine the effect of DPAA on CNS. We believe that continuous monitoring of the DPAA-exposed people may promote the effect of carcinogen and accelerate brain aging.

  13. Ten Year Incidence of High Energy Geriatric Trauma at a Level 1 Trauma Center.

    Science.gov (United States)

    Lowe, Jason A; Pearson, Jeffrey; Leslie, Michael; Griffin, Russell

    2017-10-14

    To examine the characteristics of high-energy geriatric trauma over time. Retrospective chart review SETTING:: Level 1 trauma Center PATIENTS:: Demographic, injury, and clinical characteristics were compared between 34,017 geriatric and non-geriatric high energy trauma patients from 2005-2014 using t-test, chi-square analysis and negative binomial regression for annual trend in injuries. High-energy geriatric trauma comprised 11.2% of all trauma activations. High-energy geriatric patients nearly doubled from the study period of 2005-2014 to previous 10 years (p=0.0004). Compared to non-geriatric patients, geriatric high-energy traumas were twice as likely to be due to fall from height (pgeriatric patients (OR 4.76, 95% CI 4.00-5.67), and high-energy mechanisms (OR 4.71, 95% CI 3.90-5.68) compared to low-energy mechanisms (OR 3.00, 95% CI 2.48-3.62). The number of geriatric high-energy traumas has doubled over 10 years. Geriatric patients are sicker on presentation, based upon ISS score, and high-energy geriatrics have a four-fold increase in mortality. Level III.

  14. [Ten years of emergency attendances for cocaine-users in Spain].

    Science.gov (United States)

    Galicia, Miguel; Nogué, Santiago; Burillo-Putze, Guillermo

    2014-10-07

    Cocaine is the second most consumed illegal drug in the western world, following cannabis. Since 1998, it is also the drug that more attendances generate in different emergency devices, and it is responsible for more of 60% of the emergencies directly related to drug consumption. This work reviews the main Spanish scientific articles published in the last 10 years, in which different factors related to the use of this drug have been analyzed in relation to the use of emergency by cocaine users. A total of 8,795 patients were included (interval 57-1,755), with an average age of 32.64 years (SD 3.02), and an average percentage of positives to cocaine of 54.78% (SD 47.03); there were 7 works with 100% of subjects being positive to cocaine. Males predominated with an average of 78.69% (SD 12). They presented cardiovascular symptoms in 30% cases (SD 22.7), neurological symptoms in 11.6% cases (SD 4.28) and psychiatric symptoms in 49.32% cases (SD 23.87). There was a multiple consumption in 49.02% of patients (interval 4.3-76.2), fundamentally associated with alcohol (57.78%, SD 6.18) and cannabis (21.56%, SD 10.72). Two hundred and forty-six patients (2.8%) needed admission and 8 died (0.09%). Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  15. The Last Ten Years of Advancements in Plant-Derived Recombinant Vaccines against Hepatitis B

    Directory of Open Access Journals (Sweden)

    Young Hee Joung

    2016-10-01

    Full Text Available Disease prevention through vaccination is considered to be the greatest contribution to public health over the past century. Every year more than 100 million children are vaccinated with the standard World Health Organization (WHO-recommended vaccines including hepatitis B (HepB. HepB is the most serious type of liver infection caused by the hepatitis B virus (HBV, however, it can be prevented by currently available recombinant vaccine, which has an excellent record of safety and effectiveness. To date, recombinant vaccines are produced in many systems of bacteria, yeast, insect, and mammalian and plant cells. Among these platforms, the use of plant cells has received considerable attention in terms of intrinsic safety, scalability, and appropriate modification of target proteins. Research groups worldwide have attempted to develop more efficacious plant-derived vaccines for over 30 diseases, most frequently HepB and influenza. More inspiring, approximately 12 plant-made antigens have already been tested in clinical trials, with successful outcomes. In this study, the latest information from the last 10 years on plant-derived antigens, especially hepatitis B surface antigen, approaches are reviewed and breakthroughs regarding the weak points are also discussed.

  16. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    Science.gov (United States)

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2012-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gender, age, and race) predicted the shape of the trajectories and likelihood of class membership. As hypothesized, membership in the chronic harassment classes was linked to future problematic drinking, even after controlling for previous drinking. PMID:21745045

  17. Epidemiology of Cervical Spine Injuries in High School Athletes Over a Ten-Year Period.

    Science.gov (United States)

    Meron, Adele; McMullen, Christopher; Laker, Scott R; Currie, Dustin; Comstock, R Dawn

    2017-09-12

    More than 7 million athletes participate in high school (HS) sports annually, with both the benefits of physical activity and risks of injury. Although catastrophic cervical spine injuries have been studied, limited data are available that characterize less-severe cervical spine injuries in HS athletes. To describe and compare cervical spine injury rates and patterns among U.S. HS athletes across 24 sports over a 10-year period. Descriptive epidemiology study. National sample of high schools participating in the High School Reporting Information Online injury surveillance system. Athletes from participating schools injured in a school sanctioned practice, competition, or performance during the 2005-2006 through 2014-2015 academic years. Cervical spine injury data captured by the High School Reporting Information Online system during the 10-year study period were examined. Cervical spine injury was defined as any injury to the cervical spinal cord, bones, nerves, or supporting structures of the cervical spine including muscles, ligaments, and tendons. Cervical spine injury rates, diagnoses, mechanisms, and severities. During the study period, 1080 cervical spine injuries were reported during 35,581,036 athlete exposures for an injury rate of 3.04 per 100,000 athlete exposures. Injury rates were highest in football (10.10), wrestling (7.42), and girls' gymnastics (4.95). Muscle injuries were most common (63.1%), followed by nerve injuries (20.5%). A larger proportion of football injuries were nerve injuries compared with all other sports (injury proportion ratio 3.31; confidence interval 2.33-4.72), whereas in boys' ice hockey fractures represented a greater proportion of injuries compared with all other sports (injury proportion ratio 7.64; confidence interval 2.10-27.83). Overall, the most common mechanisms of injury were contact with another player (70.7%) and contact with playing surface (16.1%). Cervical spine injury rates and patterns vary by sport and gender

  18. Ten years of the Three Gorges Dam: a call for policy overhaul

    Science.gov (United States)

    Yang, Xiankun; Lu, X. X.

    2013-12-01

    The Three Gorges Dam (TGD), the world’s largest source of ‘clean’ hydroelectric power (Shen and Xie 2004), has entered its tenth year after the first turbine went into operation in June 2003. The dam, with a generating capacity 20 times that of the United States’ Hoover Dam, has been hailed as a crucial part of a solution to China’s energy crisis. Despite great benefits, however, major concerns have been voiced over the disastrous environmental and social consequences of this massive engineering project (Stone 2011). In this paper, we review the benefits and impacts learned from the controversial megadam over the past decade and discuss perspective quests on policy overhaul for future environmental protection.

  19. Ten-year Pollution Characteristics of Particulate-associated Polycyclic Aromatic Hydrocarbons in Beijing, China

    Science.gov (United States)

    Zhu, Xianlei; Deng, Changjiang; Biandan, Luobu; Fu, Xianqiang; Mu, Xilong

    2015-04-01

    Polycyclic aromatic hydrocarbons (PAHs) are well-known air pollutants of health concern. However, they are not listed as routinely measured pollutants in China, in spite of benzo[a]pyrene (BaP) being included in the National Ambient Air Quality Standard (NAAQS). Thus, very limited continuous measurements are available for PAHs, which would hinder the understanding of long-term pollution characteristics of PAHs in context of rapid development of economy and intensive urbanization in China. To investigate annual variation and its causes of airborne particulate-associated PAHs, a total of 18 PAHs (including 16 USEPA priority species) in PM10 and PM2.5 were measured in Beijing, the capital and one of megacities of China, for a decade (from the year of 2004 to 2013) with meteorological data simultaneously recorded. The long-term measurements of PAHs showed significant annual and seasonal variations for the total concentration of PAHs (ΣPAH18) and individual PAH species. The ΣPAH18 in PM10 was highest in 2010 and lowest in 2006. Likewise, the ΣPAH18 in PM2.5 reached the highest level in 2010 and dropped to the lowest level in 2005. The annual concentration varied insignificantly for 2- and 3-ring PAHs, were relatively high in the year of 2004, 2007 and 2010 for 4-ring PAHs, and increased gradually with year for 5- to 7-ring PAHs, the markers of motor vehicle emission. As for seasonal variation, the concentrations in winter (heating period) was higher than those in summer, while concentrations in spring and autumn ranked in the middle. As for BaP, one of criteria pollutants, its concentration exceeded NAAQS of China in winter. Source apportionment by factor analysis suggested the contributions of coal combustion, vehicle emissions, fugitive dust and straw burning. Especially, the great contributions of coal combustion and vehicle emission were also supported by diagnostic ratios. The backward trajectories showed air mass crossing polluted cities and transporting in low

  20. [Lengthening technique of the ulna in Kienboeck's disease. Results after ten years].

    Science.gov (United States)

    Roullet, J; Walch, G

    1982-01-01

    The writers had re-examined several patients who had an operation for Kienböck disease before 1970. All had had an elongation of ulna through the same technique and no other operation for pseudarthrosis had been necessary. Eight patients were able to be examined 14.7 years after their operation (on an average). The analytical functional results were evaluated following Michon's criteria. The best results had been obtained as far as pain and strenght of the wrist were concerned, yet those obtained on mobility proved disappointing. X-Rays showed a lunatum keeping its shape 6 times out of 8 and an almost constant development of arthrosis. The use of the technique is questioned in the treatment of Kienböck disease.

  1. Ten years of Integrated Pest Management (IPM at the Kunsthistorisches Museum in Wien

    Directory of Open Access Journals (Sweden)

    Pascal Querner

    2011-08-01

    Full Text Available The Kunsthistorisches Museum Wien is one of the largest fine arts collections worldwide, comprising the Kunsthistorisches Museum, the Austrian Theater Museum, the Museum of Ethnology, all placed in Vienna, and Schloß Ambras in Tirol. We present results from up to 10 years of insect pest monitoring in different collections and the implementation of an Integrated Pest Management (IPM concept. The Kunsthistorisches Museum was the first museum in Vienna to introduce such a concept. We also present specific insect pest problems such as a biscuit beetle (Stegobium paniceum infestation of paintings lined with starch paste backings (linings or the webbing clothes moth (Tineola bisselliella infestation at the Museum of Carriages, both repeatedly occurring problems in the museum. With the help of the insect pest monitoring programs, these and other problems were found and the infested objects treated, usually with anoxia (nitrogen.

  2. Ten years of infliximab (remicade) in clinical practice: the story from bench to bedside.

    Science.gov (United States)

    Cornillie, Freddy

    2009-11-25

    Infliximab was first introduced in Europe in 1999 for Crohn's disease. During the following decade major progress was made in the understanding of the pathophysiology of inflammatory bowel diseases and treatment with infliximab. Today, treatment algorithms with anti-TNF and optimization of anti-TNF use in daily clinical practice are important research topics in Crohn's disease and ulcerative colitis. TNF blockade has also changed the rheumatology practice during the last 10 years. Earlier treatment, combination with disease modifying anti-rheumatic drugs, and identification of risk factors of poor prognosis are hot research topics today. The introduction of infliximab (among other biological therapies) has thus changed the way how inflammatory bowel diseases and rheumatoid conditions are treated. More importantly, infliximab has offered significant improvement of the quality of life of many patients. In addition, we currently collect data indicating that infliximab is changing the natural course of these inflammatory diseases.

  3. Ten years of unitization in Brazil; Dez anos de unitizacoes no Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Bonolo, Daniel Dellamora; Almeida, Mateus Passeri de [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The unitization concept, as used by the oil industry, was established in Brazil through Art 27 of the Law 9.478/97, also known as the Petroleum Law, and the first process was initiated in 2002. Within these 10 years, four processes were started and finalized, approved by ANP. These processes were developed in a maturing regulatory environment, which was improved in 2010. This article deals with the peculiarities of these processes, putting in context the regulatory framework and doubts at the time. We also verse about the regulatory scene after 2010, pointing out the main enhancements made. It is concluded that, although essential, an elaborated regulation is not the only important factor for the success of a unitization agreement, but also the agreement between parties, which has been encouraged by ANP.(author)

  4. A disturbed child's use of a public event: Cotard's syndrome in a ten-year-old.

    Science.gov (United States)

    Allen, J R; Pfefferbaum, B; Hammond, D; Speed, L

    2000-01-01

    Public events can be incorporated into the mental life and life narratives of children with psychiatric illnesses. A 10-year-old boy who was not in Oklahoma City at the time of the 1995 bombing of the Murrah Federal Building and who knew no one directly impacted, claimed that he himself was dead, then that his grandfather, and finally that a peer and the peer's family had been killed in the blast. This is the first known reported case of Cotard's syndrome, the delusion of being dead, in a prepubescent child. The article also explores the relationships between this boy's symptoms, transference phenomena, real life events, themes of loss, abandonment, neglect, and death, and his fabricated stories.

  5. Ten Years of Vegetation Change in Northern California Marshlands Detected using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher

    2013-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology was applied to detected changes in perennial vegetation cover at marshland sites in Northern California reported to have undergone restoration between 1999 and 2009. Results showed extensive contiguous areas of restored marshland plant cover at 10 of the 14 sites selected. Gains in either woody shrub cover and/or from recovery of herbaceous cover that remains productive and evergreen on a year-round basis could be mapped out from the image results. However, LEDAPS may not be highly sensitive changes in wetlands that have been restored mainly with seasonal herbaceous cover (e.g., vernal pools), due to the ephemeral nature of the plant greenness signal. Based on this evaluation, the LEDAPS methodology would be capable of fulfilling a pressing need for consistent, continual, low-cost monitoring of changes in marshland ecosystems of the Pacific Flyway.

  6. [A bibliometrics study of literature on medical image processing for the past ten years].

    Science.gov (United States)

    Chen, Wei; Wang, Yanbin; Ouyang, Zhaolian; Guo, Wenjiao; Chi, Hui

    2014-02-01

    We searched and retrieved literature on the topic of medical image processing published on SCI journals in the past 10 years. We then imported the retrieved literature into TDA for data cleanup before data analysis and pro cessing by EXCLE and UCINET to generate tables and figures that could indicate disciplinary correlation and research hotspots from the perspective of bibliometrics. The results indicated that people in Europe and USA were leading researchers on medical image processing with close international cooperation. Many disciplines contributed to the fast development of medical image processing with intense interdisciplinary researches. The papers that we found show recent research hotspots of the algorithm, system, model, image and segmentation in the field of medical image processing. Cluster analysis on key words of high frequency demonstrated complicated clustering relationship.

  7. Ten years of tuberculosis intervention in Greenland - has it prevented cases of childhood tuberculosis?

    DEFF Research Database (Denmark)

    Birch, Emilie; Andersson, Mikael; Koch, Anders

    2014-01-01

    -2010 (intensified interventions). Risk of TB was estimated using Poisson regression. RESULTS: The study included 35,858 children, of whom 209 had TB disease. The TB disease incidence decreased after interventions were implemented (2007-2010: IRR [incidence rate ratios] 0.62, 95% CI: 0.39-0.95, p=0.03, compared...... with the 1995-1999 period). The TB disease risk was inversely associated with BCG vaccination (IRR: 0.54, 95% CI: 0.41-0.72, pdisease incidence among children ≤15 years......BACKGROUND: The incidence of tuberculosis (TB) disease in Greenland doubled in the 1990s. To combat the increase, national TB interventions were initiated in 2000 and strengthened in 2007. OBJECTIVE: To determine whether the effect of interventions could be detected, we estimated the TB disease...

  8. Pediatric oral burns: a ten-year review of patient characteristics, etiologies and treatment outcomes.

    Science.gov (United States)

    Cowan, Douglas; Ho, Brian; Sykes, Kevin J; Wei, Julie L

    2013-08-01

    To summarize etiologies and treatments of pediatric oropharyngeal burns. Retrospective summary of 75 patients treated from January 1999 to January 2009. Tertiary Children's Hospital. Data collected included demographics, etiology of burn, site of injury, medical and/or surgical treatments, need for endoscopy, duration of hospitalization, and complications. 75 patients were treated with 50 being males (66%). Mean age was 4.3 years (median 2.7 years). The five most common causes were chemical (34.6%), electrical (12.3%), hot liquids (12.3%), food (12.3%) and battery ingestion (9.9%). Ingestion of hair products made up nearly 1/3 of the chemical causes (9/28) and alone made up 12% of the burns in our study. Main sites of injury included buccal mucosa (77.3%), lips (56%), tongue (48%), and palate (22.7%). One-third of the patients' required PICU/Burn unit admissions, 1/3 were admitted to floor, and 1/3 were discharged home from the ED. Average duration of hospitalization was 5 days. Of those admitted, 30% received antibiotics and only 8% received systemic steroids. Patients were made NPO on the first day of admission in 33.3% of patients and allowed to resume normal diet after surgical consultation. Only 9/75 (12%) patients required intubation. Otolaryngology consultation was obtained in 10.7% of cases. Only 18% of all patients required surgical intervention with debridement being most common (>60%). In this group, 20% received esophagogastroduodenoscopies due to ingestion of alkali substance. Complications occurred in less than 6% of all cases. Ingestion of chemicals, including hair dye/relaxer products, as well as overheated liquids and foods, are leading causes of oropharyngeal burns treated at our Children's Hospital Emergency Department over the past decade. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  9. A ten years (2000–2009 surveillance of resistant Enterobacteriaceae in Zhejiang Province, China

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    Rong Zhang

    2012-03-01

    Full Text Available Objective: In Zhejiang Province, there are several highly developed cities near the coast and several relatively under-developed mountain areas. Analysis of the composition of bacteria isolated from patients as well as their antibiotic resistance profile from various areas of this province, and tracing of such data year-by-year, will help to delineate the bacterial resistance profile of these areas and to understand how the stage of socio-economical development impacts on the composition of clinical micro-flora and their resistance profile. Methods: In order to investigate variation in resistance rates and isolation rates of Enterobacteriaceae, from 2000 to 2009 in Zhejiang Province, China, Enterobacteriaceae isolated from 15 hospitals located in different regions of the province were surveyed. Results: The total numbers of the Enterobacteriaceae isolated increased more than 20-fold from 2000 to 2009. Among the Enterobacteriaceae, Escherichia coli and Klebsiella pneumoniae were the dominant isolates. The percentage of E. coli and K. pneumoniae that produced detectable extended-spectrum ?-lactamases (ESBLs increased from 2000 to 2007, and then declined slightly in 2008 and 2009. The percentages of K. pneumoniae and E. coli that were resistant to ceftazidime increased sharply from 2000 to 2009. There were remarkable increases in the carbapenem resistant rates during the decade, but they were much higher for the isolates from the developed cities than from the rural areas. In 2002, carbapenem-resistant E. coli was first found in Hangzhou, one of the highly developed cities in Zhejiang Province. By 2009, carbapenem-resistant bacteria were found for all species of Enterobacteriaceae surveyed in almost all areas of the province, although they were more frequently identified in developed areas than in rural areas. Conclusion: Much restrictive actions have to be taken in terms of rational use of antibiotics and nosocomial control to prevent the further

  10. Ten-year quality control of a semiautomated procedure of cord blood unit volume reduction.

    Science.gov (United States)

    Lecchi, Lucilla; Perego, Lucia; Garcea, Filomena; Ratti, Ilaria; Brasca, Manuela; Dotti, Deborah; Cimoni, Silvia; Pezzali, Ilaria; Celeste, Teresa; Giovanelli, Silvia; Butti, Barbara; De Fazio, Nicola; Lopa, Raffaella; Rebulla, Paolo

    2009-03-01

    Volume reduction of cord blood units decreases the cost of cryogenic storage. This study reports the analysis of a 10-year quality control program of a semiautomated cord blood volume reduction procedure. Cord blood was collected in a plastic bag containing 29 mL citrate-phosphate-dextrose, centrifuged at 2124 x g for 12 minutes, and processed with a semiautomated device. The procedure was aimed at removing most red blood cells and plasma and concentrating hematopoietic progenitors in the buffy coat (BC), thus reducing the unit volume and saving cryogenic space. Finally, the BC was cryopreserved with an equal volume of 20 percent dimethyl sulfoxide. Total nucleated cells (TNCs) were counted before and after processing in the 4311 units banked from 1998 through 2007, whereas CD34+ cells and colony-forming units-granulocyte-macrophage (CFU-GM) were counted in 420 random units from 2001 through 2007. Mean postvolume reduction annual recoveries of TNCs, CD34+ cells, and CFU-GM ranged from 82.8 +/- 12.3 (standard deviation) to 91.4 +/- 6.4 percent, from 87.8 +/- 14.1 to 95.2 +/- 23.8 percent, and from 101.5 +/- 51.4 to 117.8 +/- 59.5 percent, respectively. Very strong correlations were found (r > 0.87) between postprocessing versus preprocessing TNCs, CD34+ cells, and CFU-GM; a moderate correlation between initial TNC count and unit's volume (r = 0.51); and no correlation between TNC percentage of recovery in the BC and initial unit's volume. The latter data indicate that most TNCs concentrate in the BC. The semiautomated procedure of cord blood unit volume reduction used in this study provides high and stable cellular recoveries during several years of routine cord blood banking.

  11. Ten year trend analysis of malaria prevalence in Kola Diba, North Gondar, Northwest Ethiopia

    Directory of Open Access Journals (Sweden)

    Alemu Abebe

    2012-08-01

    Full Text Available Abstract Background Malaria is caused by protozoan parasites of the genus Plasmodium. It is one of the leading causes of illness and death in the world. It is a major public health problem in Ethiopia. Over the past years, the disease has been consistently reported as the first leading cause of outpatient visits, hospitalization and death in health facilities across the country. Methods A retrospective study was conducted to determine the prevalence of malaria from peripheral blood smear examinations from the Kola Diba Health Center of Ethiopia. The case notes of all malaria cases reported between 2002–2011 were carefully reviewed and analyzed. Additionally, any malaria intervention activities that had been taken to control malaria were collected using a well-prepared checklist from the study area. Results Within the last decade (2002–2011 a total of 59, 208 blood films were requested for malaria diagnosis in Kola Diba health center and 23,473 (39.6% microscopically confirmed malaria cases were reported in the town with a fluctuating trend. Regarding the identified plasmodium species, Plasmodium falciparum and Plasmodium vivax accounted for 75% and 25% of malaria morbidity, respectively. Malaria was reported in all age groups and both sexes, but the 15–44 year age group and males were more affected. Despite the apparent fluctuation of malaria trends in the area, the highest peak of malaria cases was reported during spring seasons. Conclusion Comparatively, after the introduction of the current malaria control strategies, the morbidity and mortality by malaria is decreasing but malaria is still a major health problem and the deadly species P. falciparium is predominant. Therefore, control activities should be continued in a strengthened manner in the study area considering both P. falciparium and P. vivax.

  12. Ten Year Follow-Up of Gap Balanced, Rotating Platform Total Knee Arthroplasty in Patients Under 60 Years of Age.

    Science.gov (United States)

    Lee, Jason H; Barnett, Steven L; Patel, Jay J; Nassif, Nader A; Cummings, Dennis J; Gorab, Robert S

    2016-01-01

    68 patients (91 primary total knee arthroplasties) were evaluated at a mean 10-year, minimum 5 year follow up in patients younger than sixty years of age utilizing the gap balanced, rotating platform design. Follow up assessment included implant survivorship, adverse events, x-rays, Knee Society rating system and clinical evaluation. Three revisions were performed with only one for aseptic loosening at 45 months. Two manipulations were performed in the early postoperative period. Survivorship of the rotating platform, gap balanced knee was 96.7% using surgical revision for any reason and 98.9% using aseptic loosening as endpoints. The rotating platform design using the gap balancing technique in young patients had excellent survivorship at 10-year mean follow up. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Frequency of upper extremity nerve entrapment syndromes in surgically operated patients: a ten-year study

    Directory of Open Access Journals (Sweden)

    Farzan M

    2009-12-01

    Full Text Available "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Nerve entrapment neuropathies are relatively frequent in the upper limb. Significant costs related to resultant disability and treatment, and also simultaneous occurrence of some of these syndromes can result in alteration in the treatment approach. The aim of this study was to evaluate the frequency of these syndromes, the rate of concurrence of carpal tunnel syndrome as the most prevalent syndrome with others, related risk factors, and accordance of clinical and electrophysiological findings."n"nMethods: In a retrospective study, data of the 170 affected patients to these syndromes operated during a period of 10 years in a referral center were searched using recorded documents. Information about patient's gender, age, occupation and associated co-morbidities, clinical and surgical findings and their accordance to the EMG-NCV findings, and also concurrence of these syndromes were assessed."n"nResults: Patients' range of age was 10-91 year (mean: 48.09 year and 74.5% of them were female. In this study carpal tunnel and cubital tunnel syndrome were the most frequent (81.7% and 15.8% respectively. In 23.5% of patients with carpal tunnel syndrome, electrophysiological findings were negative but there

  14. First Year Experience Course: Insights from the First Two Years

    Science.gov (United States)

    Erickson, Sheri L.; Stone, Mary F.

    2012-01-01

    Retention rates of students in a business school Freshman Year Experience (FYE) course were compared to overall University retention rates for two successive years. Slightly higher retention was experienced by the business FYE students than for the University overall. Student responses to exit survey questions were compared to retention activity…

  15. Unemployment in TB patients - ten-year observation at regional center of pulmonology in Bydgoszcz, Poland.

    Science.gov (United States)

    Przybylski, Grzegorz; Dabrowska, Anita; Pilaczyńska-Cemel, Marta; Krawiecka, Dorota

    2014-11-02

    Tuberculosis (TB) affects the poorest of the poor and is an example of a disease that can contribute to the "disease-poverty trap". The variable epidemiological situation is associated with social risk factors, such as unemployment, which may favor the occurrence of this disease. The aim of this study was to analyze unemployment as a factor that can influence the incidence and course of the disease. We analyzed TB patients with confirmed status of employment or unemployment admitted to the Regional Center of Pulmonology in Bydgoszcz in during the years 2001 to 2010. Out of 1130 patients, 604 were unemployed and the other confirmed their employment. The unemployed patients were mostly single men over age 40, with a low level of education, and living in a city. We observed that the proportions of smokers and alcohol abusers were significantly higher among the unemployed patients. The advanced radiological lesions, smear-positive pulmonary TB, and extra-pulmonary sites were diagnosed significantly more often in this group. The rate of death in the course of hospitalization was significantly higher in the group of unemployed patients. Unemployment among TB patients is a serious problem. We found that more advanced radiological lesions were associated with more frequent treatment interruptions and a higher rate of death in the course of hospitalization. Increased efforts are needed to reduce and eliminate the problem of unemployment among patients with TB. This may, indirectly, contribute to a decrease in notifications of TB cases and improve treatment outcomes.

  16. A Ten-Year Molecular Survey on Parvoviruses Infecting Carnivores in Bulgaria.

    Science.gov (United States)

    Filipov, C; Desario, C; Patouchas, O; Eftimov, P; Gruichev, G; Manov, V; Filipov, G; Buonavoglia, C; Decaro, N

    2016-08-01

    Parvoviruses represent the most important infectious agents that are responsible for severe to fatal disease in carnivores. This study reports the results of a 10-year molecular survey conducted on carnivores in Bulgaria (n = 344), including 262 dogs and 19 cats with gastroenteritis, and 57 hunted wild carnivores. Real-time polymerase chain reaction (qPCR), followed by virus characterization by minor groove binder (MGB) probe assays, detected 216 parvovirus positive dogs with a predominance of canine parvovirus type 2a (CPV-2a, 79.17%) over CPV-2b (18.52%) and CPV-2c (2.31%). Rottweilers and German shepherds were the most frequent breeds among CPV-positive pedigree dogs (n = 96). Eighteen cats were found to shed parvoviruses in their faeces, with most strains being characterized as FPLV (n = 17), although a single specimen tested positive for CPV-2a. Only two wild carnivores were parvovirus positive, a wolf (Canis lupus) and a red fox (Vulpes vulpes), both being infected by CPV-2a strains. © 2014 Blackwell Verlag GmbH.

  17. Biosolids Effects in Chihuahuan Desert Rangelands: A Ten-Year Study

    Directory of Open Access Journals (Sweden)

    David B. Wester

    2011-01-01

    Full Text Available Arid and semiarid rangelands are suitable for responsible biosolids application. Topical application is critical to avoid soil and vegetation disturbance. Surface-applied biosolids have long-lasting effects in these ecosystems. We conducted a 10-year research program investigating effects of biosolids applied at rates from 0 to 90 dry Mg ha−1 on soil water infiltration; runoff and leachate water quality; soil erosion; forage production and quality; seedling establishment; plant physiological responses; nitrogen dynamics; biosolids decomposition; and grazing animal behavior and management. Biosolids increased soil water infiltration and reduced erosion. Effects on soil water quality were observed only at the highest application rates. Biosolids increased soil nitrate-nitrogen. Biosolids increased forage production and improved forage quality. Biosolids increased leaf area of grasses; photosynthetic rates were not necessarily increased by biosolids. Biosolids effects on plant establishment are expected only under moderately favorable conditions. Over an 82-mo exposure period, total organic carbon, nitrogen, and total and available phosphorus decreased and inorganic matter increased. Grazing animals spent more time grazing, ruminating, and resting in biosolids-treated areas; positive effects on average daily gain were observed during periods of higher rainfall. Our results suggest that annual biosolids application rates of up to 18 Mg ha−1 are appropriate for desert rangelands.

  18. Precipitation Climatology over Mediterranean Basin from Ten Years of TRMM Measurements

    Science.gov (United States)

    Mehta, Amita V.; Yang, Song

    2008-01-01

    Climatological features of mesoscale rain activities over the Mediterranean region between 5 W-40 E and 28 N-48 N are examined using the Tropical Rainfall Measuring Mission (TRMM) 3B42 and 2A25 rain products. The 3B42 rainrates at 3-hourly, 0.25 deg x 0.25 deg spatial resolution for the last 10 years (January 1998 to July 2007) are used to form and analyze the 5-day mean and monthly mean climatology of rainfall. Results show considerable regional and seasonal differences of rainfall over the Mediterranean Region. The maximum rainfall (3-5 mm/day) occurs over the mountain regions of Europe, while the minimum rainfall is observed over North Africa (approximately 0.5 mm/day). The main rainy season over the Mediterranean Sea extends from October to March, with maximum rainfall occurring during November-December. Over the Mediterranean Sea, an average rainrate of approximately 1-2 mm/day is observed, but during the rainy season there is 20% larger rainfall over the western Mediterranean Sea than that over the eastern Mediterranean Sea. During the rainy season, mesoscale rain systems generally propagate from west to east and from north to south over the Mediterranean region, likely to be associated with Mediterranean cyclonic disturbances resulting from interactions among large-scale circulation, orography, and land-sea temperature contrast.

  19. Ten years of transcriptomics in wild populations: what have we learned about their ecology and evolution?

    Science.gov (United States)

    Alvarez, Mariano; Schrey, Aaron W; Richards, Christina L

    2015-02-01

    Molecular ecology has moved beyond the use of a relatively small number of markers, often noncoding, and it is now possible to use whole-genome measures of gene expression with microarrays and RNAseq (i.e. transcriptomics) to capture molecular response to environmental challenges. While transcriptome studies are shedding light on the mechanistic basis of traits as complex as personality or physiological response to catastrophic events, these approaches are still challenging because of the required technical expertise, difficulties with analysis and cost. Still, we found that in the last 10 years, 575 studies used microarrays or RNAseq in ecology. These studies broadly address three questions that reflect the progression of the field: (i) How much variation in gene expression is there and how is it structured? (ii) How do environmental stimuli affect gene expression? (iii) How does gene expression affect phenotype? We discuss technical aspects of RNAseq and microarray technology, and a framework that leverages the advantages of both. Further, we highlight future directions of research, particularly related to moving beyond correlation and the development of additional annotation resources. Measuring gene expression across an array of taxa in ecological settings promises to enrich our understanding of ecology and genome function. © 2015 John Wiley & Sons Ltd.

  20. Incidence of Symptomatic Congenital Toxoplasmosis During Ten Years in a Brazilian Hospital.

    Science.gov (United States)

    Bischoff, Adrianne Rahde; Friedrich, Luciana; Cattan, Jacobo Melamed; Uberti, Flávio Antonio de Freitas

    2016-12-01

    Population seroprevalence and rates of mother-to-child transmission are important in determining the incidence of congenital toxoplasmosis. (CT) Mother-to-child transmission depends on the timing of acute maternal infection and treatment during pregnancy. The incidence of CT varies widely across geographic regions, ranging from 1 to 10 cases per 10,000 live births. The incidence of symptomatic disease varies from 0.15 to 0.34 cases per 10,000. This is a review of patients treated at a pediatric CT clinic at a university hospital in the south of Brazil, from 2004 to 2014. The annual incidence of CT varied from 0 to 14 cases per 10,000 live births, with a mean incidence of 6 cases per 10,000 during the 10 years studied (CI 95%: 3.02-8.91). The incidence of symptomatic CT varied from 0 to 9 cases per 10,000 live births, with a mean incidence of 5 per 10,000 (CI 95%: 2.44-6.94). There were 5 (14.3%) asymptomatic cases. The main findings were retinochoroiditis (54%), intracranial calcifications (37.5%) and altered cerebrospinal fluid (37.5%). The incidence of CT and the rate of symptomatic cases were in accordance with the previous data from other studies in Brazil, being significantly higher than in previous North American and European studies.

  1. Reassessing "Jacob's case": a serial killer re-examined after ten years.

    Science.gov (United States)

    Kalian, M; Birger, M; Witztum, E

    2004-01-01

    The current study re-examines an exceptional case of a serial killer incarcerated since a decade ago. "Jacob" is the first serial killer apprehended in Israel. His known actions were committed during the eighties of the last century, and continued for eleven years. The victims were elderly individuals, including both his parents. Shortly after incarceration he became overtly schizophrenic and underwent five hospitalisations. The case is re-examined in view of changes, both in the perpetrator's diagnosis and criminal legislation. Was Jacob doomed to become a serial killer, or could his fate be avoided through early professional intervention? Were the killings presenting symptoms of a psychotic or pre-psychotic phase? Should he be eligible for a retrial? What would have been his position with the current law in view of the new 300A(a) clause ("Reduced Punishment") of the Israeli Criminal Code? Could he ever be released back to the community? These are some of the questions to be addressed.

  2. Durability of Pultruded GFRP through Ten-Year Outdoor Exposure Test

    Directory of Open Access Journals (Sweden)

    Itaru Nishizaki

    2015-11-01

    Full Text Available Pultrusion is an easy molding method of fiber-reinforced polymer (FRP to obtain a long composite material with a uniform cross-section at relatively low cost. In some cases, pultruded FRPs are now used in bridges and deck projects. Since the application of pultruded FRP as a structural material is increasing, a study on the durability of pultruded FRP under outdoor conditions is necessary in terms of safety. Some studies have shown that pultruded glass fiber-reinforced polymer (GFRP exhibits a slight reduction in mechanical properties during outdoor exposure. Since pultruded GFRP consists of multi-layers, the change of mechanical properties in each layer is important to understand. In this study, an outdoor exposure test on pultruded GFRP for 10 years was conducted with three types of pultruded GFRP, which have different laminate systems, including surface-coated specimens of each type. Changes of strength and elastic modulus due to outdoor exposure were discussed with a focus on the contribution of each layer based on the rule of mixtures.

  3. Ten years of Italian historiography of psychology: a field in progress.

    Science.gov (United States)

    Ceccarelli, Glauco; Cimino, Guido; Foschi, Renato

    2010-08-01

    This article briefly outlines a picture of the activities and research conducted in Italy on the history of psychology during the last 10 years, focusing its attention on institutions, scholars, conferences, archives, journals, and so forth. At the dawn of the 21st century, the tradition of historical-psychological studies that developed in the last quarter of the 20th century has led to a renewed situation in teaching organization and research, with the emergence of several groups, especially at the universities of Rome "Sapienza", Bari, Milan-Bicocca, and Urbino, and of a second generation of young historians increasingly engaged on an international level. After a general survey conducted with historiometric method on the principal areas of research cultivated and on the themes dealt with, we mention a change that has occurred in the historiographical approach, a transition from a historiography addressed prevalently to the "history of ideas" to one that, pursuing the approach of a new and critical "multifactorial" history, proves to be more attentive to the social and institutional history, in correspondence with established international trends.

  4. Ten Years of Land Cover Change on the California Coast Detected using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher S.

    2013-01-01

    Landsat satellite imagery was analyzed to generate a detailed record of 10 years of vegetation disturbance and regrowth for Pacific coastal areas of Marin and San Francisco Counties. The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology, a transformation of Tasseled-Cap data space, was applied to detected changes in perennial coastal shrubland, woodland, and forest cover from 1999 to 2009. Results showed several principal points of interest, within which extensive contiguous areas of similar LEDAPS vegetation change (either disturbed or restored) were detected. Regrowth areas were delineated as burned forest areas in the Point Reyes National Seashore (PRNS) from the 1995 Vision Fire. LEDAPS-detected disturbance patterns on Inverness Ridge, PRNS in areas observed with dieback of tanoak and bay laurel trees was consistent with defoliation by sudden oak death (Phytophthora ramorum). LEDAPS regrowth pixels were detected over much of the predominantly grassland/herbaceous cover of the Olema Valley ranchland near PRNS. Extensive restoration of perennial vegetation cover on Crissy Field, Baker Beach and Lobos Creek dunes in San Francisco was identified. Based on these examples, the LEDAPS methodology will be capable of fulfilling much of the need for continual, low-cost monitoring of emerging changes to coastal ecosystems.

  5. Ten years of maintaining and expanding a microbial genome and metagenome analysis system.

    Science.gov (United States)

    Markowitz, Victor M; Chen, I-Min A; Chu, Ken; Pati, Amrita; Ivanova, Natalia N; Kyrpides, Nikos C

    2015-11-01

    Launched in March 2005, the Integrated Microbial Genomes (IMG) system is a comprehensive data management system that supports multidimensional comparative analysis of genomic data. At the core of the IMG system is a data warehouse that contains genome and metagenome datasets sequenced at the Joint Genome Institute or provided by scientific users, as well as public genome datasets available at the National Center for Biotechnology Information Genbank sequence data archive. Genomes and metagenome datasets are processed using IMG's microbial genome and metagenome sequence data processing pipelines and are integrated into the data warehouse using IMG's data integration toolkits. Microbial genome and metagenome application specific data marts and user interfaces provide access to different subsets of IMG's data and analysis toolkits. This review article revisits IMG's original aims, highlights key milestones reached by the system during the past 10 years, and discusses the main challenges faced by a rapidly expanding system, in particular the complexity of maintaining such a system in an academic setting with limited budgets and computing and data management infrastructure. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Ten-Year Longitudinal Trajectories of Older Adults’ Basic and Everyday Cognitive Abilities

    Science.gov (United States)

    Yam, Anna; Gross, Alden; Prindle, John; Marsiske, Michael

    2014-01-01

    Objective To examine the longitudinal trajectories of everyday cognition and longitudinal associations with basic (i.e., laboratory and experimentally measured) cognitive abilities, including verbal memory, inductive reasoning, visual processing speed, and vocabulary. Method Participants were healthy older adults drawn from the no-treatment control group (N = 698) of the ACTIVE randomized trial, and were assessed at baseline and 1, 2, 3, 5, and 10 years later. Analyses were conducted using latent growth models. Results Modeling revealed an overall inverted “U” shape (quadratic) trajectory across cognitive domains. Among basic cognitive predictors, level and slope in reasoning demonstrated the closest association to level and slope of everyday cognition, and accounted for most of the individual differences in linear gain in everyday cognition. Conclusions Everyday cognition is not buffered against decline, and is most closely related to inductive reasoning in healthy older adults. To establish the clinical utility of everyday cognitive measures, future research should examine these associations in samples with more cognitive impairment. PMID:24885451

  7. Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator.

    Science.gov (United States)

    Salinas, Maria; López-Garrigós, Maite; Flores, Emilio; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2015-01-01

    Preanalytical control and monitoring continue to be an important issue for clinical laboratory professionals. The aim of the study was to evaluate a monitoring system of preanalytical errors regarding not suitable samples for analysis, based on different indicators; to compare such indicators in different phlebotomy centres; and finally to evaluate a single synthetic preanalytical indicator that may be included in the balanced scorecard management system (BSC). We collected individual and global preanalytical errors in haematology, coagulation, chemistry, and urine samples analysis. We also analyzed a synthetic indicator that represents the sum of all types of preanalytical errors, expressed in a sigma level. We studied the evolution of those indicators over time and compared indicator results by way of the comparison of proportions and Chi-square. There was a decrease in the number of errors along the years (P<0.001). This pattern was confirmed in primary care patients, inpatients and outpatients. In blood samples, fewer errors occurred in outpatients, followed by inpatients. We present a practical and effective methodology to monitor unsuitable sample preanalytical errors. The synthetic indicator results summarize overall preanalytical sample errors, and can be used as part of BSC management system.

  8. A Ten-Year Investigation on Ozone and It Precursors at Kemaman, Terengganu, Malaysia

    Directory of Open Access Journals (Sweden)

    Marzuki Ismail

    2016-01-01

    Full Text Available 10 years of continuous monitoring data (2000-2010 from Air Quality Division, Malaysian Department of Environment are used to investigate the relationships between ambient levels of ozone (O3, nitric oxide (NO and nitrogen dioxide (NO2 as a function of NOx, in Kemaman, Malaysia, wherewith the dominant sources of ozone precursors are industrial activities and road traffic. In addition, variation of oxidant OX (O3 and NO2 concentration with NOx was also examined. The analyses established a weak linear relationship between O3 and NOx, signifying that Kemaman area is not NOx sensitive but possibly VOC-sensitive area. The level of [OX] is influenced byNOx-independent and NOx-dependent contributions. The former is due to regional background O3 concentration while the latter correlates to the local level of primary pollution. The measured concentrations of the pollutants varied as a function of time. The analyses also show that the diurnal cycle of ground level ozone concentration has a mid-day peak while lower concentration occurs at night time.

  9. Ten years of anti-HPV vaccinations: what do we know?

    Directory of Open Access Journals (Sweden)

    Robert Jach

    2016-11-01

    Full Text Available Human papillomavirus (HPV is one of the most important carcinogens in humans. Vaccines against HPV are now considered the first anti-cancer vaccinations. Since 2007, in many developed countries, there have been recommendations present for preventive vaccines against HPV. At present, the degree of implementation of these recommendations depends on a number of country-specific factors such as the health care system organization or the ways of funding. HPV vaccines are primarily to prevent the development of cervical cancer and other genital cancers. Therefore, only their long-term effectiveness can be measured, when a correspondingly large cohort of vaccinated teenagers reaches the age of the greatest incidence of these cancers. However, great care should be taken in assessing the results of vaccinations due to the possibility of misinterpretation and possible erroneous data. Undoubtedly, teenagers are the target population of HPV vaccines. However, vaccinating young sexually active women is also justified from an individual point of view. A 9-valent vaccine has been registered in the USA and in Europe – including Poland – as one of the three preventive vaccines. It is recommended to vaccinate women between 13 and 26 and men between 13 and 21, previously unvaccinated. It is also recommended to vaccinate men aged 26 years or less who have sexual relations with other men and people with reduced immunity, including HIV-positive people who have not been vaccinated previously.

  10. Ten Year Analysis of Tropopause-Overshooting Convection Using GridRad Data

    Science.gov (United States)

    Cooney, John W.; Bowman, Kenneth P.; Homeyer, Cameron R.; Fenske, Tyler M.

    2018-01-01

    Convection that penetrates the tropopause (overshooting convection) rapidly transports air from the lower troposphere to the lower stratosphere, potentially mixing air between the two layers. This exchange of air can have a substantial impact on the composition, radiation, and chemistry of the upper troposphere and lower stratosphere (UTLS). In order to improve our understanding of the role convection plays in the transport of trace gases across the tropopause, this study presents a 10 year analysis of overshooting convection for the eastern two thirds of the contiguous United States for March through August of 2004 to 2013 based on radar observations. Echo top altitudes are estimated at hourly intervals using high-resolution, three-dimensional, gridded, radar reflectivity fields created by merging observations from available radars in the National Oceanic and Atmospheric Administration Next Generation Weather Radar (NEXRAD) network. Overshooting convection is identified by comparing echo top altitudes with tropopause altitudes derived from the ERA-Interim reanalysis. It is found that overshooting convection is most common in the central United States, with a weak secondary maximum along the southeast coast. The maximum number of overshooting events occur consistently between 2200 and 0200 UTC. Most overshooting events occur in May, June, and July when convection is deepest and the tropopause altitude is relatively low. Approximately 45% of the analyzed overshooting events (those with echo tops at least 1 km above the tropopause) have echo tops extending above the 380 K level into the stratospheric overworld.

  11. Visual disability rates in a ten-year cohort of patients with anterior visual pathway meningiomas.

    Science.gov (United States)

    Bor-Shavit, Elite; Hammel, Naama; Nahum, Yoav; Rappaport, Zvi Harry; Stiebel-Kalish, Hadas

    2015-01-01

    To examine the visual outcome of anterior visual pathway meningioma (AVPM) patients followed for at least one year. Data were collected on demographics, clinical course and management. Visual disability was classified at the first and last examination as follows: I--no visual disability; II--mild visual defect in one eye; III--mild visual defect in both eyes; IV--loss of driver's license; V--legally blind. Eight-one AVPM patients had their tumor originate in the clinoid process in 23 (28%), sphenoid-wing area in 18 (22%), cavernous sinus in 15 (19%), tuberculum sellae in 8 (10%), and mixed in 17 (21%). On last examination, 46 patients (57%) had good visual acuity in one or both eyes (Class I or II) and 17 (21%) were mildly affected in both eyes. The rate of Class IV disability was 16%, and Class V disability was 6%. Attention needs to be addressed to the considerable proportion of patients with AVPM (22% in this study) who may lose their driver's license or become legally blind. Occupational therapists should play an important role in the multidisciplinary management of those patients to help them adapt to their new physical and social situation. Anterior visual pathway meningiomas (AVPMs) are commonly not life-threatening but they can lead to profound visual disability, especially when the tumor originates in the tuberculum sellae and cavernous sinus. Particular attention should be paid to visual acuity and visual field deficits, as these can profoundly affect the patient's quality of life including ability to drive and activities of daily living. The interdisciplinary management of patients with AVPM should include the neurosurgeon, neuro-ophthalmologist and occupational therapist. Also, early intervention by the occupational therapist can help patients adapt to their current physical and social situation and return to everyday tasks more rapidly.

  12. Ten Years of Equine-related Injuries: Severity and Implications for Emergency Physicians.

    Science.gov (United States)

    Davidson, Scott B; Blostein, Paul A; Schrotenboer, Andrew; Sloffer, Chris A; VandenBerg, Sheri L

    2015-11-01

    The size, speed, and unpredictable nature of horses present a significant risk for injury in all equine-related activities. We sought to examine the mechanism, severity, frequency, body regions affected, surgical requirements, rehabilitation needs, safety equipment utilization, and outcomes of equine-related injured patients. Records of inpatients who sustained an equine-related injury from 2002-2011 with International Classification of Diseases, Ninth Revision codes E828 and E906 were retrospectively reviewed for pertinent data. Ninety patients, 70% female, age (mean ± SD) 37.3 ± 19.4 years, length of stay 3.7 ± 4.5 days, Injury Severity Score 12.9 ± 8.4. Predominant mechanism of injury was fall from horse (46.7%). The chest (23%) was most frequently injured, followed by brain/head (21.5%). Thirty patients (33%) required 57 surgical procedures. Twenty percent of patients required occupational therapy and 33.3% required physical therapy while hospitalized. Only 3% required rehabilitation, with 90% discharged directly home. Safety equipment was not used in 91.9% of patients. One patient sustained a cord injury. Six patients expired, all from extensive head injuries. The majority of equine-related injuries occur while pursuing recreational activities and are due to falls. Our patients experienced more severe injuries to the trunk and head and required more surgical intervention for pelvic, facial, and brain injuries than previously reported. Failure to use safety equipment contributes to the risk of severe injury. Education and injury prevention is essential. The need for complex surgical intervention by multiple specialties supports transfer to Level I trauma centers. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Henoch-Schönlein purpura outcome in children: A ten-year clinical study

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    Spasojević-Dimitrijeva Brankica

    2011-01-01

    Full Text Available Introduction. Henoch-Schönlein purpura (HSP is the most common vasculitis of childhood. It is characterized by symptoms including nonthrombocytopenic purpura, abdominal pain, haematuria/proteinuria, and arthralgia/arthritis. The pleiomorphism of clinical signs in HSP could be confused with other conditions or other vasculitis forms. Objective. Evaluation of HSP clinical presentation, the onset and severity of renal manifestation in affected children and their outcome. Methods. A retrospective study of 49 patients diagnosed with HSP was conducted from September 1999 to September 2009. Children with severe renal manifestations (nephrotic range proteinuria, with or without nephrotic or nephritic syndrome have undergone kidney biopsy. Results. Twenty-five patients developed renal manifestations after onset of the disease. In our study child’s older age was a risk factor for association with HSP nephritis. Six of the patients required kidney biopsy. They were successfully treated with various immunosuppressive protocols, as well as three of nine patients with nephrotic range proteinuria. Two patients developed most severe form of HSP nephritis, nephrotic-nephritic syndrome with histology grade IIIb/IVb. During the study period (average follow-up 6 years, all patients had a normal global renal function with mild proteinuria in only two cases. The prognosis of renal involvement was better than reports from other patient series. Conclusion. Long-term morbidity of HSP is predominantly attributed to renal involvement. During the study period, no patient had renal insufficiency or end stage renal disease after various combinations of immunosuppressive treatment. It is recommended that patients with HSP nephritis are followed for longer periods of time with a regular measurement of renal function and proteinuria.

  14. Ten-year trends in overweight and obesity in the adult Portuguese population, 1995 to 2005

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    Ravasco Paula

    2011-10-01

    Full Text Available Abstract Background There is little information regarding the trends in body mass index (BMI and obesity in the overall Portuguese population, namely if these trends are similar according to educational level. In this study, we assessed the trends in the prevalence of overweight and obesity in the Portuguese population, overall and by educational level. Methods Cross-sectional national health interview surveys conducted in 1995-6 (n = 38,504, 1998-9 (n = 38,688 and 2005-6 (n = 25,348. Data were derived from the population and housing census of 1991 and two geographically-based strata were defined. The sampling unit was the house, and all subjects living in the sampling unit were surveyed. Height and weight were self-reported; the effects of gender, age group and educational level were also assessed by self-reported structured questionnaires. Bivariate comparisons were performed using Chi-square or analysis of variance (ANOVA. Trends in BMI levels were assessed by linear regression analysis, while trends in the prevalence of obesity were assessed by logistic regression. Results Mean (±standard deviation BMI increased from 25.2 ± 4.0 in 1995-6 to 25.7 ± 4.5 kg/m2 in 2005-6. Prevalence of overweight remained stable (36.1% in 1995-6 and 36.4% in 2005 while prevalence of obesity increased (11.5% in 1995-6 and 15.1% in 2005-6. Similar findings were observed according to age group. Mean age-adjusted BMI increase (expressed in kg/m2/year and 95% confidence interval was 0.073 (0.062, 0.084, 0.016 (0.000, 0.031 and 0.073 (0.049, 0.098 in men with primary, secondary and university levels, respectively; the corresponding values in women were 0.085 (0.073, 0.097, 0.052 (0.035, 0.069 and 0.062 (0.038, 0.084. Relative to 1995-6, obesity rates increased by 48%, 41% and 59% in men and by 40%, 75% and 177% in women with primary, secondary and university levels, respectively. The corresponding values for overweight were 6%, 1% and 23% in men and 5%, 7% and 65

  15. Rheumatic symptoms in childhood leukaemia and lymphoma-a ten-year retrospective study.

    Science.gov (United States)

    Zombori, Luca; Kovacs, Gabor; Csoka, Monika; Derfalvi, Beata

    2013-01-01

    The initial symptoms of childhood leukaemia and lymphoma are often similar to those of juvenile idiopathic arthritis (JIA). In our study, we analyzed the frequency and characteristics of musculoskeletal complaints as the initial presenting symptoms of newly diagnosed leukaemia and lymphoma patients in the past 10 years in our clinic. Using the Hungarian Tumour Register, we performed a retrospective analysis of the medical records of 166 new leukaemia and 95 new lymphoma pediatric patients treated from 1999 to 2009 at the 2nd. Dept. of Paediatrics of the Semmelweis University in Budapest. Twenty percent of the leukaemic (33 children) and 2% of the lymphoma patients (2 children) had musculoskeletal symptoms at first presentation. Two-thirds of both groups of patients had other general symptoms like fever and/or fatigue. The hip was the most frequently affected joint (7/33) in the leukaemic patients. Twenty-four percent of all the children had been previously evaluated by an orthopaedist; 12% had visited another rheumatologist prior to diagnosis. Imaging had been done in an unexpectedly low number of patients prior to referral to our unit (radiographs: 16 or 48%, ultrasound: 5 patients or 15%). Radiographs of the affected joints were abnormal in only one case (1/16, 6%). The joint ultrasound was abnormal in only three children of 5 studied (3/5, 60%). Anaemia (26/32, 6%), thrombocytopenia (78%) and LDH elevation (3-4 times the normal count) were frequent in the leukaemic patients. Half of the cases had a normal leukocyte count. The lymphoma group had similar results. Two patients of the leukaemia group received steroid treatment before the final diagnosis. Severe pain out of proportion to physical findings is another clue. Haematologic malignancies must be excluded before initiation of therapy for childhood arthritis among children presenting with musculoskeletal signs and symptoms, particularly in atypical cases. Malignancies are to be suspected when pain is

  16. Ten years of Aeolus II - 3 MW; 10 Jahre Aeolus II - 3 MW

    Energy Technology Data Exchange (ETDEWEB)

    Wendt, H.; Knuenz, D. [Aeolus-Betriebsgesellschaft mbH, Ottersberg (Germany)

    2004-07-01

    On 15 October 1992, PreussenElektra commissioned the 3 MW Aeolus II wind power plant in Jade wind park near Wilhelmshaven. The plant was developed and produced in a joined venture of Kvaerner Turbin AG, Sweden, and Messerschmidt Boelkow Blohm, MBB, Germany, and funded by the EC WEGA II programme through the German state of Niedersachsen, The BMFT, and PreussenElektra. Two institutes, FFA Sweden and Deutsches Windenergie-Institut (DEWI) cooperated in the project. After 8 years of operation, the prototype plant was sold by E.ON (formerly PreussenElektra) to Aeolus Betriebsgesellschaft mbH, Ottersberg, in May 2000. Measurements were made by DEWI from January 1994 through June 1995, with the following results: The technical availability in the first half of 1995 was 91.8 percent. This is excellent in view of the fact that the plant is a prototype in an unusual size. The power coefficient curve can compete with those of the 500-600 kW category, except for the fact that the system shuts off already at a wind speed of 20 m/s. (orig.) [German] Am 15. Oktober 1992 nahm die PreussenElektra im Jade Windpark bei Wilhelmshaven die 3 MW Windkraftanlage Aeolus II in Betrieb. Eine Kooperation zwischen der Kvaerner Turbin AG aus Schweden und der Messerschmidt Boelkow Blohm, MBB, Deutschland, uebernahm Entwicklung und Produktion der Anlage. Finanziert wurde der Prototyp durch die EG im Rahmen des WEGA II Programms, durch das Land Niedersachsen, das Bundesministerium fuer Forschung und Technologie, BMFT, und der PreussenElektra. Am Projekt beteiligt waren die Institute FFA Schweden und das Deutsches Windenergie-Institut (DEWI). Nach 8 Betriebsjahren wurde der Prototyp im Mai 2000 von der E.ON (vorm. PreussenElektra) an die Aeolus Betriebsgesellschaft mbH in Ottersberg verkauft. Vom 01.01.1994 bis zum 30.6.1995 wurde die Anlage durch das DEWI vermessen. Das DEWI bewertet die Anlage im August 1995 nach Abschluss der Vermessung wie folgt: Fuer das erste Halbjahr 1995 ergibt sich eine

  17. Pre-natal diagnosis of thalassaemia in Sri Lanka: A ten year review.

    Science.gov (United States)

    Nanayakkara, Kalinga Khemal; Rodrigo, Undugodage Ganganath; Perera, Kuda Liyanage Nandika; Nanayakkara, Chinthani Deepthi

    2017-10-01

    Thalassaemia is the commonest monogenic disease in Sri Lanka, affecting over 3500 children and half-a-million thalassaemia carriers. This is a review of 82 amniocenteses performed from 2006 to 2016, in the largest prenatal diagnoses study for thalassaemia carried out in Sri Lanka. Amniocenteses were performed between 11 and 12 weeks of ultrasonically confirmed gestation, on mothers with previous thalassaemia major children pregnant for the second time and nulliparous thalassaemia trait women married to trait partners. The Consultant Radiologist, using local analgesia, under ultrasound cover, performed these as an outpatient procedure, at the Teaching Hospital Kandy & Suwasevana Hospital Kandy. The amniotic fluid was analysed by the team of Senior Geneticists, at the Genetech Molecular Diagnostics and School of Gene Technology, Colombo, via the polymerase-chain-reaction based ARMS (Amplification Refractory Mutation Systems) assay. The genetic results indicated the presence of 21% thalassaemia major foetuses, 53% thalassaemia traits and 26% foetuses without thalassaemia mutations. The predominance of the IVS1-5(G-C) mutation in the Sri Lankan population is exemplified, with a low prevalence of HbE thalassaemia. Impact statement Thalassaemia is the commonest monogenic disease in Sri Lanka affecting over 3500 children and half-a-million thalassaemia carriers. Although pre-natal diagnosis by amniocentesis was practised universally for many years, this could not be performed in Sri Lanka as genetic diagnostic facilities were not available until 2005. Therefore, parents with a thalassaemia major child limited their families to one child, by choice or by termination. The results of this study point to a 21% probability of thalassaemia major in the next child, giving the parents a guarded optimism to conceive another child without thalassaemia disease. With siblings being the highest HLA compatibility for Bone Marrow Transplant, that is now being established in Sri Lanka

  18. Peer-review and editorial process of the Ethiopian Medical Journal: ten years assessment of the status of submitted manuscripts.

    Science.gov (United States)

    Enquselassie, Fikre

    2013-04-01

    The Ethiopian Medical Journal (EMJ) is a peer-reviewed journal, now 50 years old. Many medical journals, including EMJ, follow a peer review system that has evolved from the 18th century process for reviewing submitted manuscripts. However, not much is known about peer review and editorial processes by many authors who submit manuscripts to the EMJ. To describe procedures related to EMJ peer-review and editorial decision making and asses the status of manuscripts submitted to the journal in the ten year period between 2001 and 2010. All the minutes of the editorial board meetings of the ten years period 2001-2010 and relevant documents were reviewed. The minutes have details including date of submission, dates to and from reviewers, date of decision, number of assigned peer reviewers and comments given by reviewers for each submitted manuscript. The length of time took in the processes and the decision made (accepted or rejected) for each submitted manuscript was calculated from the dates. All submitted manuscripts passed through three stages: internal per-review by an editorial board member, external peer review by selected reviewers and final editing stage by an assigned editorial member. A total of 615 manuscripts were submitted to EMJ in the ten years period 2001-2010. Five hundred and one (82.7%) manuscripts were accepted for publication by peer reviewers, while 74 (12.2%) were rejected and 31 (5.1%) were withdrawn. Acceptance was lowest among original articles (81.3%) followed by teaching or review articles (84.3%) and case reports (89.3%). Thirty-two (8.4%) manuscripts were accepted within 6 months following submission and 50% were accepted within in one year of submission. About 6% of manuscripts were delayed for more than two years with a maximum delay of 43 months. Even though, there is a decline trend on the delay of processing manuscripts, EMJ has long to go in order to improve the quality of the journal and shorten the slow peer review process

  19. The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament

    Directory of Open Access Journals (Sweden)

    Patt Thomas W

    2008-06-01

    Full Text Available Abstract Objective The objective of this study was to evaluate the incidence of radiographic osteoarthritis in the operated knee in comparison with the contralateral knee ten years after a bone-tendon bone patellar autograft ACL-reconstruction and to evaluate to which level patients regain activity ten years after reconstruction. Methods Fifty-three patients with ACL instability were operated arthroscopically using the central third of the patellar tendon as a bone-tendon-bone autograft. At a minimum of 10 year follow up 28/44 patients matched the inclusion criteria and could be reached for follow-up. Evaluation included a patient satisfaction evaluation using a Visual Analog Scale, physical examination (International Knee Documentation Committee score, Tegner score, Lysholm score, KT-1000 stabilometry and a radiological evaluation (Kellgren and Fairbanks classification. Results The patients' satisfaction, at a mean of 10,3 year follow-up, measured with a VAS score (0–10 was high with a mean of 8.5 (range 4 to 10. The KT 1000 arthrometer laxity measurements revealed in 55% of the patients an A rating (1–2 mm, in 29% a B rating (3–5 mm and in 16% a C rating (6–10 mm. According to the Tegner score 54% of the patients were able to perform at the same activity level as pre-operatively. The mean pre-operative Tegner score was 6.8 and the mean post-operative Tegner score was 6.0 at final follow up. The Lysholm score showed satisfactory results with a mean of 91 points (range 56 to 100. According to the Kellgren and Fairbank classifications, there is a significant difference (p Conclusion The patellar BTB ACL reconstruction does not prevent the occurrence of radiological OA after 10 years but does help the patient to regain the pre-operative level of activity.

  20. Ten-year echo/doppler determination of the benefits of aerobic exercise after the age of 65 years.

    Science.gov (United States)

    Muster, Alexander J; Kim, Hyunggun; Kane, Bonnie; McPherson, David D

    2010-01-01

    As the human lifespan becomes progressively extended, potential health-related effects of intense aerobic exercise after age 65 need evaluation. This study evaluates the cardiovascular (CV), pulmonary, and metabolic effects of competitive distance running on age-related deterioration in men between 69 (+/-3) and 77 (+/-2) years (mean +/- SD). Twelve elderly competitive distance runners (ER) underwent oxygen consumption and echo/Doppler treadmill stress testing (Balke protocol) for up to 10 years. Twelve age-matched sedentary controls (SC) with no history of CV disease were similarly tested and the results compared for the initial three series of the study. CV data clearly separated the ER from SC. At entry, resting and maximal heart rate, systolic/diastolic blood pressure, peak oxygen consumption (VO(2max)), and E/A ratio of mitral inflow were better in the ER (P aerobic exercise were demonstrated in the ER when compared to SC. Importantly, data collected in ER over 10 years confirm the benefit of intensive exercise for slowing several negative effects of aging. However, the normative drop of exercise capacity in the seventh and eighth decades reduces the potential athleticism plays in prevention of CV events.

  1. Trace element contamination in the Guadalquivir River Estuary ten years after the Aznalcóllar mine spill.

    Science.gov (United States)

    Tornero, Victoria; Arias, Alberto M; Blasco, Julián

    2014-09-15

    Sediments, clams Scrobicularia plana and worms Hediste diversicolor from the Guadalquivir estuary were collected ten years after the Aznalcóllar mine spill and analyzed for metals. Significant seasonal and spatial effects were detected for most elements, so data from different sampling periods and locations were treated separately. Overall, the most polluted sites were found upstream, although Zn and Cu tended to accumulate at the estuary mouth. A significant decline of Zn in sediments and clams was observed compared to levels reported following the spill, so the estuarine ecosystem has recovered. However, the concentrations of some elements in S. plana were still higher than those of heavily contaminated regions. In this mollusk, Pb and As levels were higher in 2008 than in previous years, suggesting a new source entering into the estuary. Metals in sediments presented low bioavailability for biota, so other sources must account for the concentrations observed in these species. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Socioeconomic position and ten-year survival and virologic outcomes in a Ugandan HIV cohort receiving antiretroviral therapy.

    Directory of Open Access Journals (Sweden)

    Andrew G Flynn

    Full Text Available Lifelong ART is essential to reducing HIV mortality and ending the epidemic, however the interplay between socioeconomic position and long-term outcomes of HIV-infected persons receiving antiretroviral therapy (ART in sub-Saharan Africa is unknown. Furthering the understanding of factors related to long-term ART outcomes in this important region will aid the successful scale-up of ART programs. We enrolled 559 HIV-infected Ugandan adults starting ART in 2004-2005 at the Infectious Diseases Institute in Kampala, Uganda and followed them for 10 years. We documented baseline employment status, regular household income, education level, housing description, physical ability, and CD4 count. Viral load was measured every six months. Proportional hazard regression tested for associations between baseline characteristics and 1 mortality, 2 virologic failure, and 3 mortality or virologic failure as a composite outcome. Over ten years 23% (n = 127 of participants died, 6% (n = 31 were lost-to-follow-up and 23% (107/472 experienced virologic treatment failure. In Kaplan-Meier analysis we observed an association between employment and mortality, with the highest cumulative probability of death occurring in unemployed individuals. In univariate analysis unemployment and disease severity were associated with mortality, but in multivariable analysis the only association with mortality was disease severity. We observed an association between higher household income and an increased incidence of both virologic failure and the combined outcome, and an association between self-employment and lower incidence of virologic failure and the combined outcome when compared to unemployment. Formal education level and housing status were unrelated to outcomes. It is feasible to achieve good ten-year survival, retention-in-care, and viral suppression in a socioeconomically diverse population in a resource-limited setting. Unemployment appears to be related to adverse 10

  3. Multifocal osteonecrosis related to corticosteroid: ten years later, risk of progression and observation of subsequent new osteonecroses.

    Science.gov (United States)

    Flouzat-Lachaniette, Charles-Henri; Roubineau, François; Heyberger, Clemence; Bouthors, Charlie; Hernigou, Philippe

    2016-04-01

    No study has reported the risk of other site osteonecroses after the diagnosis of multifocal osteonecrosis related to corticosteroids in patients who continue this corticosteroid treatment. An analysis of the time-course to other sites of osteonecrosis, as well as the effects of underlying corticosteroid risk factor on the evolution of asymptomatic lesions at the time of diagnosis, is presented. Two hundred patients were followed prospectively every year during a minimum ten years with a radiograph if a joint became symptomatic. In absence of evidence of osteonecrosis on radiographs of a symptomatic or non-symptomatic joint (hips, shoulders, knees, ankles), patients had an MRI performed at the most recent follow up. The average duration of follow-up after inclusion of the patient in the study was 15 years (range 10-20). Of the 200 patients followed for an average of 15 years (minimum 10 years, maximum 20 years), 35 patients developed new osteonecrosis lesions during the period of study. Asymptomatic lesions became symptomatic and a high number of collapse was observed resulting in 258 arthroplasties (187 hips, 51 shoulders, 20 knees) at the most recent follow up. The continuation of peak doses (>200 mg) of corticosteroids predicted (p = 0.04) occurrence of new lesions and the continuation of corticosteroids without peak dose was a risk for quicker progression to collapse.

  4. Learning from lawsuits: Ten-years of NHS litigation authority claims against 11 surgical specialities in England.

    Science.gov (United States)

    Ford, Kathryn E; Cooper, Lilli R L

    2016-05-06

    Medico-legal claims are a drain on NHS resources and promote defencive practice. The litigious burden of surgery in England has not been previously described. This paper describes trends over ten years of claims made against the NHS across 11 surgical specialities. Data were requested for all claims received by the NHS Litigation Authority (NHSLA) from 2004 to 2014. Surgical specialities included cardiothoracic, general, neurosurgery, obstetric, oral and maxillofacial (OMFS), orthopaedic, otorhinolaryngology, paediatric, plastic, urology and vascular surgery. A literature review of peer-reviewed publications was performed with search terms 'NHSLA' and 'Surgery'. The NHS paid out approximately £1.5 billion across 11 surgical specialities from 2004 to 2014. Orthopaedic, obstetric and general surgery received the largest number of claims per year, and paediatric surgery the least. The mean time from registration of claim with the NHSLA to settlement was 25.5 months (range 17.8 months-35 months). Neurosurgery was responsible for the highest average amount paid per claim, and OMFS the lowest. Failure/delay in treatment and/or diagnosis and failure to warn/adequately consent were the three leading types of claim. 806 never events were successfully claimed for during the ten-year period. Sharing information and good practice should be a priority for surgical professionals. Lessons learnt from medico-legal claims are transferrable in strategic planning. This pan-speciality report has demonstrated considerable burden on the NHS and should promote improvement in practice on an individual level in addition to providing systems based recommendations to NHS and international organisations. Copyright © 2016 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  5. Advanced HIV Disease at Enrolment in HIV Care: Trends and Associated Factors over a Ten Year Period in Cambodia.

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    Reaksmey Pe

    Full Text Available Early HIV diagnosis and enrolment in care is needed to achieve early antiretroviral treatment (ART initiation. Studies on HIV disease stage at enrolment in care from Asian countries are limited. We evaluated trends in and factors associated with late HIV disease presentation over a ten-year period in the largest ART center in Cambodia.We conducted a retrospective analysis of program data including all ARV-naïve adults (> 18 years old enrolling into HIV care from March 2003-December 2013 in a non-governmental hospital in Phnom Penh, Cambodia. We calculated the proportion presenting with advanced stage HIV disease (WHO clinical stage IV or CD4 cell count <100 cells/μL and the probability of ART initiation by six months after enrolment. Factors associated with late presentation were determined using multivariate logistic regression.From 2003-2013, a total of 5642 HIV-infected patients enrolled in HIV care. The proportion of late presenters decreased from 67% in 2003 to 44% in 2009 and 41% in 2013; a temporary increase to 52% occurred in 2011 coinciding with logistical/budgetary constraints at the national program level. Median CD4 counts increased from 32 cells/μL (IQR 11-127 in 2003 to 239 cells/μL (IQR 63-291 in 2013. Older age and male sex were associated with late presentation across the ten-year period. The probability of ART initiation by six months after enrolment increased from 22.6% in 2003-2006 to 79.9% in 2011-2013.Although a gradual improvement was observed over time, a large proportion of patients still enroll late, particularly older or male patients. Interventions to achieve early HIV testing and efficient linkage to care are warranted.

  6. The statistical analysis of failure of a MEVATRON77 DX67 linear accelerator over a ten year period

    CERN Document Server

    Aoyama, H; Tahara, S; Uno, H; Kadohisa, S; Azuma, Y; Nakagiri, Y; Hiraki, Y

    2003-01-01

    A linear accelerator (linac) takes a leading role in radiation therapy. A linac consists of complicated main parts and systems and it is required that highly accurate operational procedures should be maintained. Operational failure occurs for various reasons. In this report, the failure occurrences of one linac over a ten year period were recorded and analyzed. The subject model was a MEVATRON77 DX67 (Siemens, Inc). The failure rate for each system, the form classification of the contents of failure, the operation situation at the time of failure, and the average performance life of the main parts were totaled. Moreover, the relation between the number of therapies that patients received (operating efficiency) and the failure rate within that number and the relation between environment (temperature and humidity) and the failure rate attributed to other systems were analyzed. In this report, irradiation interruption was also included with situations where treatment was unable to begin in total for the number o...

  7. Ten Years Evidence-Based High-Tech Acupuncture—A Short Review of Peripherally Measured Effects

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    Gerhard Litscher

    2009-01-01

    Full Text Available Since 1997, the Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine of Graz Medical University has been dealing with the demystification of acupuncture and examining, using non-invasive methods, how different stimulation modalities (manual needle acupuncture, laserneedle acupuncture and electro acupuncture affect peripheral and central functions. Laser is also an important instrument for acupuncture. One only needs to mention the treatment of children or of patients with needle phobia. The laserneedle acupuncture, which was examined scientifically for the first time in Graz, represents a new painless acupuncture method for which up to ten laserneedles are glued to the skin, but not stuck into it. This first part of the short review article summarizes some of the peripherally measured effects of acupuncture obtained at the Medical University of Graz within the last 10 years.

  8. Ten-year follow-up of giant basilar aneurysm treated by sole stenting technique: a case report.

    Science.gov (United States)

    Zenteno, Marco; Gómez, Camilo R; Santos-Franco, Ja; Vinuela, Fernando; Aburto-Murrieta, Y; Lee, Angel

    2010-02-22

    The sole stenting technique has emerged as a new tool for the management of intracranial aneurysms. However, several concerns have emerged about the long-term behavior of intracranial stents, particularly their safety and efficacy. We present the first case of an intracranial aneurysm intentionally treated with the sole stenting technique. After ten years of clinical and imaging follow-up, the lesion has healed and no intrastent stenosis is observed.Several issues concerning this technique are discussed. For instance, the modification of the angle and intra-aneurysmal thrombosis may account as positive effects; negative outcomes include in-stent thrombosis or stenosis. This case report, involving a long clinical and imaging follow-up, provides an example of the effectiveness, safety, durability and simplicity of the sole stenting technique in the management of intracranial aneurysms.

  9. Ten-year follow-up of giant basilar aneurysm treated by sole stenting technique: a case report

    Directory of Open Access Journals (Sweden)

    Lee Angel

    2010-02-01

    Full Text Available Abstract Introduction The sole stenting technique has emerged as a new tool for the management of intracranial aneurysms. However, several concerns have emerged about the long-term behavior of intracranial stents, particularly their safety and efficacy. Case presentation We present the first case of an intracranial aneurysm intentionally treated with the sole stenting technique. After ten years of clinical and imaging follow-up, the lesion has healed and no intrastent stenosis is observed. Several issues concerning this technique are discussed. For instance, the modification of the angle and intra-aneurysmal thrombosis may account as positive effects; negative outcomes include in-stent thrombosis or stenosis. Conclusions This case report, involving a long clinical and imaging follow-up, provides an example of the effectiveness, safety, durability and simplicity of the sole stenting technique in the management of intracranial aneurysms.

  10. Rotationplasty type BI versus type BIIIa in children under the age of ten years. Should the knee be preserved?

    Science.gov (United States)

    Hardes, J; Gosheger, G; Vachtsevanos, L; Hoffmann, C; Ahrens, H; Winkelmann, W

    2005-03-01

    Type BI rotationplasty is currently indicated for children with tumours of the proximal femur whereas type BIIIa rotationplasty is reserved for those in which the entire femur has to be removed. Our aim was to compare these two types of rotationplasty and determine whether the knee should be preserved in children with tumours of the proximal femur. We compared the post-operative complications, oncological outcome, range of movement, Enneking score and radiographs of six children, who had undergone type BI rotationplasty with those of 12 who had undergone type BIIIa rotationplasty. Patients with type BI rotationplasty had a mean Enneking score of 21.6 compared with 24.4 in those with type BIIIa rotationplasty, and worse mean results in all of the parameters investigated. We conclude that type BI rotationplasty has a worse functional outcome and more complications than type BIIIa rotationplasty in children under the age of ten years.

  11. Vaccine Adverse Events Reported during the First Ten Years (1998–2008 after Introduction in the State of Rondonia, Brazil

    Directory of Open Access Journals (Sweden)

    Mônica P. L. Cunha

    2013-01-01

    Full Text Available Despite good safety records, vaccines given to young children can cause adverse events. We investigated the reported adverse events following immunization (AEFI of vaccines given to children of less than seven years of age during the first ten years (1998 to 2008 in the state of Rondonia, Brazil. We worked with the events related to BCG (Bacillus Calmett-Guérin, HB (hepatitis B, DTwP/Hib (diphtheria-tetanus-pertussis+Hemophillus influenza b, DTP (diphtheria-tetanus-pertussis, MMR (mumps, measles, rubella, and YF (yellow fever vaccines because they were part of the recommended scheme. The number of doses of vaccines given was 3,231,567 with an average of AEFI of 57.2/year during the studied period. DTwP/Hib was responsible for 298 (57.8%, DTP 114 (22.9%, HB 31 (6%, MMR 28 (5.4%, BCG 24 (4.7%, and YF 20 (3.9% of the reported AEFI. The combination of the AEFI for DTwP/Hib vaccines showed the highest number of systemic (61.4% and local events (33.8%. Young children (≤1-year old were more susceptible to AEFI occurring in the 6 hours (54.2% following vaccine uptake. This study suggests significant differences in reactogenicity of vaccines and that despite limitations of the AEFI Brazilian registry system we cannot ignore underreporting and should use the system to expand our understanding of adverse events and effects.

  12. [Disturbances of thyroid function in adult population of the city of Cracow followed up for ten years observation].

    Science.gov (United States)

    Buziak-Bereza, Monika; Gołkowski, Filip; Szybiński, Zbigniew

    2005-01-01

    The aim of the study was to define disturbances of thyroid function in adult population of the city of Cracow followed up for ten years. The analysis included the results obtained from 891 individuals, 571 females and 320 males aged 18-78 years examined prior to and after implementation of the obligatory model of iodine prophylaxis (years 1989-1990 and 1998-1999). After the exclusion of patients diagnosed earlier as having hyperthyroidism or hypothyroidism, the mean TSH level in the years 1998-1999 was significantly higher as compared to data obtained between 1989 and 1990 (1.44 microj/ml vs. 1.30 microj/ml) in the examined population. Our 10 years observation revealed an insignificant increase in frequency of hyperthyroidism only among females (1.6% vs. 0.9%) which did not indicate a clear, endemic in character increase at the population level. In the present investigations, hypothyroidism was demonstrated to occur more frequently as compared to the 1989-90 study (2.1% vs. 1.4% among females and 0.3% vs. 0% in males). Both differences were not statistically significant. As seen from the present results, over the investigated 10-year period, in the Cracow population, there occurred a clear, statistically significant (p<0.001) increase of the percentage of individuals with an elevated TPO antibody titter (3.8% vs. 11.8%). In our investigation no correlation was observed between anti-TPO antibodies and ioduria levels. The results reveal no statistically significant increase in incidence of hyperthyroidism and hypothyroidism after implementation of the obligatory model of iodine prophylaxis. The future studies are needed to clarify the mechanisms involved in increase of anti-TPO autoantibodies and verify its possible temporary nature.

  13. Helicobacter pylori (H pylori infection in Greece: the changing prevalence during a ten-year period and its antigenic profile

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    Katsilambros Nicolaos

    2002-05-01

    Full Text Available Abstract Background To evaluate changes in H pylori infection prevalence in Greece during a ten-year period, and to examine its antigenic profile. Methods Three groups of patients were studied. Group O-87: Banked serum samples of 200 consecutive adult outpatients, from the Hepato-Gastroenterology clinic of a teaching hospital at Athens, collected in 1987. Group O-97: Serum samples of 201 similarly selected outpatients from the same Unit, collected in 1997. Group BD-97: Serum samples of 120 consecutive blood donors from the same hospital, collected in 1997. H pylori IgG antibody seroprevalence was studied by a quantitative ELISA. Antigenic profile was studied by western-blot IgG assay, in 62 IgG positive patients of O-97 and BD-97. Results were analyzed by conventional statistics and multivariate regression analysis. Results The H pylori seroprevalence increased with age in the three tested groups. In O-97, seroprevalence did not differ from that, in BD-97. On the contrary, there was a significant decrease in seropositivity between O-87 and O-97 (59.5% vs 49.2%, p = 0.039. Multiple regression analysis showed that age over 35 years (OR:3.45, 95% CI:1.59–7.49, p = 0.002 and year of patients' selection – that is 1987 or 1997 – (OR:1.73, 95% CI:1.14–2.65 for 1987, p = 0.010, were independent risk factors of H pylori infection. The seroprevalence of CagA+ and VacA+ strains was 77.4% and 58.5%, respectively, and type I(CagA+/VacA+ strains were significantly more common than type II(CagA-/VacA- strains (59.7% vs 22.6%, p Conclusions During a ten-year period, we found a significant decrease of H pylori infection in Greece and our data support the birth cohort phenomenon as an explanation for the age-dependent increase of H pylori infection. The prevalence of CagA and/or VacA positive strains is relatively high, in a country with low incidence of gastric cancer.

  14. Fifteen years experience: Egyptian metabolic lab

    African Journals Online (AJOL)

    Ekram M. Fateen

    2014-08-20

    Aug 20, 2014 ... to avoid the birth of other affected children in subsequent pregnan- cies. Also, carrier detection among family members will help proper counseling and avoid birth of further affected children. Historically, the .... This study represents fif- teen years experience of biochemical diagnosis for the inherited.

  15. [Etiological aspects of acute gastroenteritis--a ten-year review (1.01. 2001-31.12.2010)].

    Science.gov (United States)

    Luca, Cătălina Mihaela; Nemescu, Roxana; Teodor, Andra; Fântânaru, Rodica; Petrovici, Cristina Mirela; Dorobăţ, Carmen

    2011-01-01

    Acute gastroentritis is one of the most common diseases in humans, and continues to be a significant cause of morbidity worldwide. To determine the bacterial pathogens associated with gastroenteritis in patients admitted to the Iasi Infectious Diseases Hospital in the last ten years. A total of 40481 stool samples were examined using conventional methods. Bacteria were found in 7.36% of cases, and parasites in 9.64%; 83% of the cases were viral, micotic, or disbiotic. The bacterial etiology was dominated by Salmonella spp. (58.34%), Shigella spp. (27.08%), Yersinia enterocolitica 03 (8.53%), Campylobacter spp. (1.31%), other bacterial pathogens (EPEC, Aeromonas hydrophilla/caviae/sobria, Plesiomonas shigelloides, Bacillus cereus, Staphylococcus aureus, etc) being detected in 3.74% of the cases. Of the Salmonella species, group B (51.99%) followed by group D (45.23%) were most common. Shigella sonnei and Shigella flexneri were found in almost the same proportion (49.45% and 49.70%, respectively); Shigella boydii was isolated in only 0.85% of cases. The trend of gastroenteritis caused by bacterial pathogens is decreasing: from 355 cases in 2001 to 105 cases in 2010; three peaks have been recorded in 2002, 2005 (when Salmonella typhi was isolated in a patient), and 2008 (469, 409, and 252 cases, respectively). Bacterial gastroenteritis affected both sexes almost equally (122 males and 118 females). The most affected age groups were: 0 - 4 years, 15 - 24 years, 5 - 14 years and 25 - 39 years. Laboratory investigations are essential in determining the etiology of gastroenteritis. Its unpredictable incidence justifies the human and material efforts aimed at controlling the spread of potentially epidemic acute gastroenteritis.

  16. The Elon Gap Experience: A Transformative First-Year Experience

    Science.gov (United States)

    Morrison, Stephen T.; Burr, Katherine H.; Waters, Rexford A.; Hall, Eric E.

    2016-01-01

    The Elon Gap Experience (EGE) was conceived out of Elon University's most recent strategic plan, the Elon Commitment (Elon University, 2009). One theme calls for "strategic and innovative pathways in undergraduate and graduate education," specifically "to launch a service program as part of a gap-year program" (Elon University,…

  17. Total phosphorus, zinc, copper, and manganese concentrations in cecil soil through ten years of poultry litter application

    Science.gov (United States)

    Poultry litter (PL) is an inexpensive and effective source of plant nutrients. However, over application could result in phosphorus and heavy metal accumulation in soils. A field experiment evaluating PL application to a Cecil soil used for cotton and corn production has been maintained for 10 years...

  18. Influence of marital status on testosterone levels-A ten year follow-up of 1113 men

    DEFF Research Database (Denmark)

    Holmboe, Stine A; Priskorn, Lærke; Jørgensen, Niels

    2017-01-01

    Based on a large population of 1113 men aged 30-60 at baseline (mean: 44.1 years, standard deviation: 10.5), we investigated whether intra-individual changes in testosterone (T) and related reproductive hormones during a ten year period were dependent of marital status at baseline and follow...... in testosterone was observed. However, independent of age and lifestyle, we observed that men who went from unmarried to married (n=81) during the study period experienced an accelerated age-related decline in testosterone (-6.6nmol/L) whereas men who went from married to unmarried (n=67) experienced...... an attenuated age-related decline (-2.3nmol/L). Men who were either married or unmarried at both time points (n=167, n=798, respectively) had a testosterone decline in between (-3.7nmol/L and -4.6nmol/L, respectively). Changes in T/LH ratio did not differ according to marital status indicating that the lowered...

  19. Land evaluation suitability for settlement based on soil permeability, topography and geology ten years after tsunami in Banda Aceh, Indonesia

    Directory of Open Access Journals (Sweden)

    Muhammad Rusdi

    2015-12-01

    Full Text Available Years after the tragedy of the tsunami in Banda Aceh researchers are still saddled with the problem of water permeability, slope and geology suitability for settlements. Social and ecological vulnerability to disasters and outcomes of Oceanic earthquakes causing tsunamis remain an indelible phobia to potential residents at the western coast of Sumatra upto the northern part of Indonesia. Ten years after the disaster, this study evaluates the topography of the area to determine the level of suitability of the area for human habitat. This article examines the concept of land suitability evaluation and its potential as a tool of determining appropriateness of a settlement. The focus of the study centered on the application of geographic information systems GIS in handling spatial data permeability, slope and geology of the land in accordance with the FAO land suitability standard. To ensure that the application works, it requires geospatial analysis compiled based on the permeability, slope and geology that can be observed and measured for the residential requirements. Results showed that almost all the cities within Banda Aceh are suitable for residency (Ordos.

  20. Ten-Year Monitored Natural Recovery of Lead-Contaminated Mine Tailing in Klity Creek, Kanchanaburi Province, Thailand.

    Science.gov (United States)

    Phenrat, Tanapon; Otwong, Ashijya; Chantharit, Aphichart; Lowry, Gregory V

    2016-10-01

    Klity Creek has become Thailand's first official remediation ordered by the court in 2013, 15 years after the spill of lead (Pb)-contaminated mine tailing into the creek. The Pollution Control Department (PCD) decided to restore the creek through monitored natural recovery (MNR) since 2006 but has not been successful. Interestingly, the most recent remediation plan in 2015 will still apply MNR to five out of the seven portions of the creek, despite no scientific feasibility evaluation of using MNR to restore the creek. This study qualitatively and quantitatively evaluated the feasibility of using MNR to clean up the creek in order to protect the Klity children from excess Pb exposure. We analyzed the physical and chemical transformation of Pb contaminated sediment in the creek and developed a remedial action goal and cleanup level using the Integrated Exposure Uptake Biokinetic model (IEUBK). We empirically determined the natural recovery (NR) potentials and rates using 10 years of data monitoring the water and sediment samples from eight monitoring stations (KC1 to KC8). Klity Creek has NR potential for water except at KC2, which is closest to the spill and the other improperly managed Pb sources. However, the creek has no NR potential for sediment except at the KC8 location (NR rate = 11.1 ± 3.0 × 10-3 month-1) farthest from the spill. The MNR method is not suitable to use as the sole remedial approach for Klity Creek (KC2 to KC7). Although MNR is applicable at KC8, it may require up to 377 ± 76 years to restore the sediment to the background Pb concentration. Phenrat T, Otwong A, Chantharit A, Lowry GV. 2016. Ten-year monitored natural recovery of lead-contaminated mine tailing in Klity Creek, Kanchanaburi Province, Thailand. Environ Health Perspect 124:1511-1520; http://dx.doi.org/10.1289/EHP215.

  1. Who requests their sperm donor's identity? The first ten years of information releases to adults with open-identity donors.

    Science.gov (United States)

    Scheib, Joanna E; Ruby, Alice; Benward, Jean

    2017-02-01

    To report findings from 10 years of requests from adults eligible to obtain their open-identity sperm donor's information. Analysis of archived family and donor data. Semistructured interviews at information releases. Not applicable. A total of 85 DI adults requesting 43 donor identities; program data on 256 DI families. None. We identified [1] demographic predictors of requesting donor identities, [2] information release timing and length, and [3] request motives. Just >35% of eligible DI adults requested their donor's identity. Adults ranged from 18-27 years, requesting at median age 18 years. More women than men requested. Proportionally fewer adults requested when they had heterosexual-couple parents, and proportionally more when they had one rather than two parents. In interviews, the common theme was wanting to know more about the donor, especially about shared characteristics. Most adults planned to contact their donor. More than 94% of adults had donors who were open to contact; adults expressed modest expectations about this contact. In 2001, the first adults became eligible to obtain their open-identity sperm donor's information. Ten years of identity requests at one program indicates that information about one's donor is important to a significant proportion of these DI adults. Most requested their donor's identity soon after becoming eligible, suggesting some urgency to wanting the information. Interview data highlighted the role of donor information in helping adults better understand themselves and their ancestry. Findings hold important implications for practice and policy. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  2. Decreased Opioid Utilization and Cost at One Year in Chronic Low Back Pain Patients Treated with Transcutaneous Electric Nerve Stimulation (TENS).

    Science.gov (United States)

    Pivec, Robert; Minshall, Michael E; Mistry, Jaydev B; Chughtai, Morad; Elmallah, Randa K; Mont, Michael A

    2015-11-01

    Chronic low back pain (CLBP) may be treated without opioids through the use of transcutaneous electrical nerve stimulation (TENS). However, no study has evaluated its clinical effect and economic impact as measured by opioid utilization and costs. The purpose of this study was to evaluate patients who were given TENS for CLBP compared to a matched group without TENS at one-year follow-up, to determine differences between opioid consumption. Opioid utilization and costs in patients who did and did not receive TENS were extracted from a Medicare supplemental administrative claims database. Patients were selected if they had at least two ICD-9-CM coded claims for low back pain in a three-month period and were then propensity score matched at a 1:1 ratio between patients who received TENS and those who did not. There were 22,913 patients in each group who had a minimum follow-up of one year. There were no significant demographic or comorbidity differences with the exception that TENS patients had more episodes of back pain. Significantly fewer patients in the TENS group required opioids at final follow-up (57.7 vs. 60.3%). TENS patients also had significantly fewer annual per-patient opioid costs compared to non-TENS patients ($169 vs. $192). There were significantly lower event rates in TENS patients compared to non-TENS patients when measured by opioid utilization (characterized by frequency of prescription refills) (3.82 vs. 4.08, respectively) or pharmacy utilization (31.67 vs. 32.25). The TENS group also demonstrated a significantly lower cost of these utilization events ($44 vs. $49) and avoided more opioid events (20.4 events fewer per 100 patients annually). Treatment of CLBP with TENS demonstrated significantly fewer patients requiring opioids, fewer events where a patient required an opioid prescription, and lower per-patient costs. Since TENS is both non-invasive and a non-narcotic, it may potentially allow physicians to be more aggressive in treating CLBP

  3. Ten-Year Trends (1999-2010) of Adherence to the Mediterranean Diet among the Balearic Islands' Adult Population.

    Science.gov (United States)

    Bibiloni, Maria Del Mar; González, Mónica; Julibert, Alicia; Llompart, Isabel; Pons, Antoni; Tur, Josep A

    2017-07-14

    The aim of this work was to assess ten-year trends (1999-2010) of adherence to the Mediterranean dietary pattern (MDP) among the Balearic Islands' adult population. Two independent cross-sectional dietary surveys (1999-2000, n = 1200 and 2009-2010 n = 1388, including participants aged 16-65 years) were carried out in the Balearic Islands, Spain. Dietary habits were assessed by means of two 24 h diet recalls and a validated semi-quantitative food-frequency questionnaire that covers 145 food items. Adherence to the MDP was defined according to a score constructed considering the consumption of nine MDP characteristic components: high monounsaturated fatty acids:saturated fatty acids (MUFA:SFA) ratio, moderate ethanol consumption, high legumes, cereals and roots, fruits, vegetables, and fish consumption, and low consumption of meat and milk. Socio-economic status, education level, lifestyle factors and health status were also assessed. Adherence to the MDP was 43.1% (SD 5.8) in 1999-2000 and 44.6% (SD 8.3) in 2009-2010. Higher age was directly associated with higher adherence to the MDP, and this association was stronger in males than in females. Young generations and smokers showed the lowest adherence to MDP, whereas people with higher educational and socio-economic level, and who were physically active showed the highest adherence. According to the place of birth, the increase in the percentage of the adherence to the MDP was observed to be smaller among the Balearic Island's natives than among people born abroad. In 2009-2010, individuals in the MDP's fourth quartile were more likely to be older (aged 46-65 years), and were less likely to have a low occupational level, to have a light physical activity level and to be smoker than in 1999-2000. The adherence to the MDP has been stabilized and slightly recovered among the Balearic Islands' adult population in the last decade.

  4. Ten-year blood pressure trajectories, cardiovascular mortality, and life years lost in 2 extinction cohorts: the Minnesota Business and Professional Men Study and the Zutphen Study.

    Science.gov (United States)

    Tielemans, Susanne M A J; Geleijnse, Johanna M; Menotti, Alessandro; Boshuizen, Hendriek C; Soedamah-Muthu, Sabita S; Jacobs, David R; Blackburn, Henry; Kromhout, Daan

    2015-03-09

    Blood pressure (BP) trajectories derived from measurements repeated over years have low measurement error and may improve cardiovascular disease prediction compared to single, average, and usual BP (single BP adjusted for regression dilution). We characterized 10-year BP trajectories and examined their association with cardiovascular mortality, all-cause mortality, and life years lost. Data from 2 prospective and nearly extinct cohorts of middle-aged men—the Minnesota Business and Professional Men Study (n=261) and the Zutphen Study (n=632)—were used. BP was measured annually during 1947-1957 in Minnesota and 1960-1970 in Zutphen. BP trajectories were identified by latent mixture modeling. Cox proportional hazards and linear regression models examined BP trajectories with cardiovascular mortality, all-cause mortality, and life years lost. Associations were adjusted for age, serum cholesterol, smoking, and diabetes mellitus. Mean initial age was about 50 years in both cohorts. After 10 years of BP measurements, men were followed until death on average 20 years later. All Minnesota men and 98% of Zutphen men died. Four BP trajectories were identified, in which mean systolic BP increased by 5 to 49 mm Hg in Minnesota and 5 to 20 mm Hg in Zutphen between age 50 and 60. The third systolic BP trajectories were associated with 2 to 4 times higher cardiovascular mortality risk, 2 times higher all-cause mortality risk, and 4 to 8 life years lost, compared to the first trajectory. Ten-year BP trajectories were the strongest predictors, among different BP measures, of cardiovascular mortality, all-cause mortality, and life years lost in Minnesota. However, average BP was the strongest predictor in Zutphen. © 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  5. Fifteen years experience: Egyptian metabolic lab

    Directory of Open Access Journals (Sweden)

    Ekram M. Fateen

    2014-10-01

    Conclusion: This study illustrates the experience of the reference metabolic lab in Egypt over 15 years. The lab began metabolic disorder screening by using simple diagnostic techniques like thin layer chromatography and colored tests in urine which by time updated and upgraded the methods to diagnose a wide range of disorders. This study shows the most common diagnosed inherited inborn errors of metabolism among the Egyptian population.

  6. Malaria in pregnancy; facts from the parasitology laboratory: a ten-year study in Abuja, North Central Nigeria

    Directory of Open Access Journals (Sweden)

    Ibecheozor, N.K.O

    2014-09-01

    Full Text Available Malaria, which is transmitted by female Anopheles mosquitoes, is the major cause of mortality among the pregnant women in the sub-Saharan Africa. A ten year study of malaria in pregnancy was carried out in Abuja, North Central Nigeria. Thick and thin blood films were stained with the Giemsa methodology. Of the 16760 pregnant women blood samples, 4571 (27.3% were positive for malaria parasites caused by Plasmodium falciparum. Of the 4571 positive cases, 75 (1.7% had parasite density of >5000 parasites/µl of blood; 148 (3.2% had between 500-5000 parasites/µl of blood; 520 (11.4% had between 50 - 500 parasites/µl of blood; while 3828 (83.7% had between 5-50 parasites/µl of blood. With the current estimate of over 4500 deaths of pregnant women in Nigeria due to malaria annually, we must make deliberate efforts to stop these unacceptable and painful losses. The continued use of malaria rapid diagnostic tests (M-RDTs methodologies should be discontinued because of its negative implications. Therefore, the microscopic laboratory diagnostic component should be included in ANC at all level of health care facility.

  7. Ten years water and energy surface balance from the CNR-ISAC micrometeorological station in Salento peninsula (southern Italy)

    Science.gov (United States)

    Martano, P.; Elefante, C.; Grasso, F.

    2015-06-01

    Data of surface-atmosphere energy and water transfer from a ten years (2003-2013) period of activity of the ISAC-Lecce micrometeorological station (isac.cnr.it"target="_blank">http://www.basesperimentale.le.isac.cnr.it) have been analyzed: to the authors' knowledge this is the first decadal data set of surface-atmosphere transfer in Salento peninsula. The surface energy budget shows a tendency to a positive bias possibly due to several reasons that require more investigations. Some suitable indices related to the surface water balance, such as the precipitation intensity, the aridity index and the ground water infiltration fraction have been calculated. Possible trends of these annual averages in the decadal period are considered, also taking into account the statistical uncertainty associated to measurement errors and missing data. The results indicate a significant increasing in the precipitation intensity together with an experimental evidence of increasing of the ground water infiltration in the measurement area, that is in agreement with recent estimations for the whole Salento peninsula. On the other hand, recent studies show that seawater intrusion and salinization of the deep underground aquifer keep increasing in the same period.

  8. Prehospital trauma care reduces mortality. Ten-year results from a time-cohort and trauma audit study in Iraq

    Directory of Open Access Journals (Sweden)

    Murad Mudhafar K

    2012-02-01

    Full Text Available Abstract Background Blunt implementation of Western trauma system models is not feasible in low-resource communities with long prehospital transit times. The aims of the study were to evaluate to which extent a low-cost prehospital trauma system reduces trauma deaths where prehospital transit times are long, and to identify specific life support interventions that contributed to survival. Methods In the study period from 1997 to 2006, 2,788 patients injured by land mines, war, and traffic accidents were managed by a chain-of-survival trauma system where non-graduate paramedics were the key care providers. The study was conducted with a time-period cohort design. Results 37% of the study patients had serious injuries with Injury Severity Score ≥ 9. The mean prehospital transport time was 2.5 hours (95% CI 1.9 - 3.2. During the ten-year study period trauma mortality was reduced from 17% (95% CI 15 -19 to 4% (95% CI 3.5 - 5, survival especially improving in major trauma victims. In most patients with airway problems, in chest injured, and in patients with external hemorrhage, simple life support measures were sufficient to improve physiological severity indicators. Conclusion In case of long prehospital transit times simple life support measures by paramedics and lay first responders reduce trauma mortality in major injuries. Delegating life-saving skills to paramedics and lay people is a key factor for efficient prehospital trauma systems in low-resource communities.

  9. The Ten Years Survey on Clinical and Epidemiologic Features of Guillain-Barre Syndrome in Sina Hospital, Hamadan, Iran

    Directory of Open Access Journals (Sweden)

    Sh. Mazaheri

    2007-07-01

    Full Text Available Introduction & Objective: Since the elimination of poliomyelitis from Iran, Guillain–Barre Syndrome (GBS has been the leading cause of acute flaccid paralysis. There are a few studies concerning clinical and epidemiologic features of Guillain-Barré syndrome in our country, therefore we evaluated ten years clinical and epidemiologic features of GBS in Sina hospital, Hamadan, Iran.Materials & Methods: In a retrospective descriptive study, we reviewed 80 records of patients with GBS who were hospitalized in Sina Hospital (Hamadan, Iran during 1993-2003. Because of incomplete data we excluded 29 patients from the study. We evaluated clinical and epidemiologic features, risk factors, lab data and management protocols. Complete remission defined as complete improved patient four weeks after the GBS treatment and partial remission as the continuation of the symptom after that time. All the data extracted manually and analyzed with SPSS software.Results: From 51 patients, 36 (70.59% were men and 15 (29.41% women, with a proportion of 2.4 men to 1 woman. The age ranged from 3 to 85 years. The highest frequency was observed in patients aged 11 to 20 (35.28%. 13 patients were student, 11 were house keeper, 11 were farmer, 7 were worker. 29 patients (56.84% had risk factors like respiratory and gastrointestinal track infection, surgery and fever before the disease onset. Complete and partial remission occurred in 17 and 28 patients respectively and 5 patients did not improve. Management failure occurred in 3 (8.83%, 2 (22.23% and 5 (62.5% patients who underwent IVIG, plasmapheresis and corticosteroids respectively.Conclusion: Our data was not similar to other studies in term of male to female proportion, age distribution and management protocols, therefore geographical pattern of the disease should be concerned for better patients’ management.

  10. Dying from cancer or other chronic diseases in the Netherlands: ten-year trends derived from death certificate data

    Directory of Open Access Journals (Sweden)

    Hingstman Lammert

    2009-02-01

    Full Text Available Abstract Background For the further development of palliative care, it is relevant to gain insight into trends in non-acute mortality. The aim of this article is twofold: (a to provide insight into ten-year trends in the characteristics of patients who died from cancer or other chronic diseases in the Netherlands; (b to show how national death statistics, derived from physicians' death certificates, can be used in this type of investigations. Methods Secondary analysis of data from 1996 to 2006 on the "primary" or "underlying" cause of death from official death certificates filled out by physicians and additional data from 2003 to 2006 on the place of death from these certificates. Results Of the 135,000 people who died in the Netherlands in 2006, 77,000 (or 57% died from a chronic disease. Cancer was the most frequent cause of death (40,000. Stroke accounted for 10,000 deaths, dementia for 8,000 deaths and COPD and heart failure each accounted for 6,000 deaths. Compared to 1996, the number of people who died from chronic diseases has risen by 6%. Of all non-acute deaths, almost three quarters were at least 70 years old when they died. Almost one third of the people died at home (31%, 28% in a hospital, 25% in a nursing home and 16% somewhere else. Conclusion Further investments to facilitate dying at home are desirable. Death certificate data proved to be useful to describe and monitor trends in non-acute deaths. Advantages of the use of death certificate data concern the reliability of the data, the opportunities for selection on the basis of the ICD-10, and the availability and low cost price of the data.

  11. Competition in Retail Electricity Markets : An Assessment of Ten Years Dutch Experience

    NARCIS (Netherlands)

    Mulder, M.; Willems, Bert

    2016-01-01

    This paper examines a decade of retail competition in the Dutch electricity market and discusses market structure, regulation, and market performance. We find a proliferation of product variety, in particular by the introduction of quality-differentiated green-energy products. Product innovation

  12. Ten years experience of isotopic breath test with special reference to Helicobacter pylori detection

    Energy Technology Data Exchange (ETDEWEB)

    Verhas, M.; Tricht, L.Van; Verschaeren, A.; Delmotte, E.; Martin, P

    1997-12-31

    The use of the carbon 14 urea breath test by comparison with culture for campylobacter of gastric endoscopic biopsies is studied in 91 patients. They were divided into 2 groups. The first group consisted of 53 patients examined by gastric endoscopy and carbon 14 urea breath test. In this population, gastric biopsies were taken at different regions of the stomach and duodenum. The breath test was performed within 3 hours after endoscopy. The second group consisted of 38 asymptomatic patients whom 23 were parent of children with campylobacter positive gastritis. For the whole population, neither antibiotic therapy nor bismuth medication was administrated within the 15 days before the realization of the test. Results were expressed in % of injected dose/mmole of CO{sub 2} after correction of endogenous production of CO{sub 2}. In conclusion, carbon 14 urea breath test is a reliable noninvasive test for detection and follow-up of gastritis caused by a widespread microorganism. Also, the precision of both tests, {sup 14} C-UBT and {sup 13} C-UBT, are compared simultaneously in 84 adults patients. The results were expressed as % of administered dose expired in 30 minutes. A better precision is observed with the {sup 13} C-UBT

  13. Correlation between flow cytometry and histologic findings: ten year experience in the investigation of lymphoproliferative diseases

    OpenAIRE

    Bezerra, Alanna Mara Pinheiro Sobreira; Pasqualin, Denise da Cunha; Guerra, João Carlos de Campos; Colombini, Marjorie Paris; Velloso, Elvira Deolinda Rodrigues Pereira; Silveira, Paulo Augusto Achucarro; Mangueira, Cristovão Luis Pitangueira; Kanayama, Ruth Hissae; Nozawa, Sonia Tsukasa; Correia, Rodolfo; Apelle, Ana Carolina; Pereira, Welbert de Oliveira; Garcia, Rodrigo Gobbo; Bacal, Nydia Strachman

    2011-01-01

    Objective: To demonstrate the advantages of correlating flow cytometry immunophenotyping with the pathology/ immunohistochemistry of lymph nodes or nodules in the diagnosis of lymphoproliferative diseases. Methods: A retrospective study was carried out of 157 biopsy or fine-needle aspiration lymph nodes/ nodule specimens taken from 142 patients, from 1999 and 2009. The specimens were simultaneously studied with fow cytometry and pathology at Hospital Israelita Albert Einstein. The specimens ...

  14. Ten Years' Experience with an E-Learning Lecture Series on Cancer Biology and Pharmacology

    Science.gov (United States)

    Efferth, Thomas

    2013-01-01

    In life sciences, the internet is an indispensable medium for research, but has not yet realized its full potential for teaching. The concept of e-learning has been developed over the past decades for undergraduate, graduate and postgraduate programs. We set up an e-learning lecture on cancer biology and pharmacology that was first offered in 2003…

  15. PARTIAL OCULOCUTANEOUS ALBINISM AND IMMUNODEFICIENCY SYNDROMES: TEN YEARS EXPERIENCE FROM A SINGLE CENTER IN TURKEY.

    Science.gov (United States)

    Patiroglu, T; Akar, H H; Unal, E; Chiang, S C; Schlums, H; Tesi, B; Ozkars, M Y; Karakukcu, M

    2016-01-01

    Partial oculocutaneous albinism and immunodeficiency (OCA-ID) diseases are autosomal recessive syndromes characterized by partial hypopigmentation and recurrent infections. Moreover, some OCA-ID syndromes confer susceptibility to develop a life-threatening hyperinflammatory condition called hemophagocytic lymphohistiocytosis (HLH). We investigated the genetic, clinical and immunological characteristics of 20 OCA patients. Herein, we present the clinical and immunological characteristics of 20 OCA patients who referred to the Department of Pediatric Immunology, Erciyes University Medical Faculty in Kayseri, Turkey between 2004 and 2014. Of the 20 OCA patients, 7 fulfilled diagnostic criteria for HLH, 9 showed defective functions of CD8 T cells and natural killer cells, and 8 received a definitive molecular diagnosis. Among the patients, we also report a patient diagnosed with two different genetic defects, in TYR and JAK3 genes, causing, respectively, OCA and ID. Our results illustrate the variability of clinical presentations and disease severity in OCA-ID patients, with consequent challenges in diagnosing and treating these patients.

  16. Ten Years Experience In Geo-Databases For Linear Facilities Risk Assessment (Lfra)

    Science.gov (United States)

    Oboni, F.

    2003-04-01

    Keywords: geo-environmental, database, ISO14000, management, decision-making, risk, pipelines, roads, railroads, loss control, SAR, hazard identification ABSTRACT: During the past decades, characterized by the development of the Risk Management (RM) culture, a variety of different RM models have been proposed by governmental agencies in various parts of the world. The most structured models appear to have originated in the field of environmental RM. These models are briefly reviewed in the first section of the paper focusing the attention on the difference between Hazard Management and Risk Management and the need to use databases in order to allow retrieval of specific information and effective updating. The core of the paper reviews a number of different RM approaches, based on extensions of geo-databases, specifically developed for linear facilities (LF) in transportation corridors since the early 90s in Switzerland, Italy, Canada, the US and South America. The applications are compared in terms of methodology, capabilities and resources necessary to their implementation. The paper then focuses the attention on the level of detail that applications and related data have to attain. Common pitfalls related to decision making based on hazards rather than on risks are discussed. The paper focuses the last sections on the description of the next generation of linear facility RA application, including examples of results and discussion of future methodological research. It is shown that geo-databases should be linked to loss control and accident reports in order to maximize their benefits. The links between RA and ISO 14000 (environmental management code) are explicitly considered.

  17. Ten years of experience with transgastric necrosectomy for walled-off necrosis in acute pancreatitis

    DEFF Research Database (Denmark)

    Busse, Malene Just; Ainsworth, Alan Patrick

    2015-01-01

    (52%), negative in 15 patients (30%); and in nine patients, no information on this was available. In all, 22 patients (44%) had one or more incidents (i.e. abdominal compartment syndrome, bleeding, new abscess, pleural effusion or delayed gastric emptying) where additional invasive therapy was needed...

  18. Reflections on ten years of using economics games and experiments in teaching

    National Research Council Canada - National Science Library

    Guest, Jonathan

    2015-01-01

    .... Some factors are discussed that might deter tutors from employing them. Unsurprisingly, one of these is the additional cost, which might make the use of online games seem more attractive, given the way...

  19. [Out-of-hospital delivery. Experience of ten years in Jalisco, Mexico].

    Science.gov (United States)

    Avalos-Huízar, Luis Manuel; de la Torre-Gutiérrez, Martha; López-Gallo, Laura; García-Hernández, Héctor; Rodríguez-Medina, David; Martínez-Verónica, Ricardo; Herrera-García, Gloria; Gutiérrez-Padilla, José Alfonso

    2010-08-01

    Birth without medical assistance, or outs hospitals is defined as one that occurs without the optimal medical and health care conditions for mother and son pairing. Frequency of this phenomenon is not known in Mexico. To observe clinical outcomes, morbidity, mortality, epidemiological and geographical patterns. A retrospective study including newborns of mothers who have had deliveries without medical assistance in accidental conditions, admitted to Unidad de Cuidados Intensivos Neonatales Externos, Hospital Civil de Guadalajara Fray Antonio Alcalde (Mexico). From January 2000 to December 2009. In 4,762 (100%) neonatal records evaluated, 582 (12%) were newborns birth for deliveries out of hospital. 314 (54%) female and 268 (46%) male, first mother's gravidity 195 (33%) and second o more gravidity 387 (68%) were registered. The Hospital stay average was 3-day. Discharge diagnoses: healthy 463 (79%), neonatal sepsis 16 (4%), respiratory distress 35 (6%), jaundice 33 (6%), pneumonia 12 (2%), metabolic disorders 13 (3%), other diagnoses 10 (2%). Place of births: 366 Guadalajara metropolitan area (63%), state of Jalisco, 180 (31%) other states of the Mexican Republic 36 (6%). Lambed at home 117 (20%), 52 bath home (9%), toilet bowl 29 (5%), car 128 (22%), road 58 (10%), hospital admission 104 (18%), Ambulance 42 (7%) Other 52 (9%). In our study we observed that 79% of the newborns were healthy. They are the third leading cause of admission to Neonatal Intensive Care Unit External. The most common neonatal complications were solved without consequence. No neonatal mortality cases were founded.

  20. Parotidectomy using the Harmonic scalpel: ten years of experience at a rural academic health center.

    Science.gov (United States)

    Polacco, Marc A; Pintea, Andrew M; Gosselin, Benoit J; Paydarfar, Joseph A

    2017-05-11

    Parotidectomy is one of the most commonly performed procedures by otorhinolaryngologists. Traditionally dissection is performed with a combination of a steel scalpel and bipolar cautery; however, starting in the early 2000s, the Harmonic scalpel has provided an alternative method for dissection and hemostasis. The purpose of this study is to compare operative time, blood loss, complications, and cost between the Harmonic scalpel and steel scalpel plus bipolar cautery for superficial and total parotidectomy. Retrospective cohort of patients who underwent superficial or total parotidectomy with the Harmonic or cold steel between 2000 and 2015. Across 255 patients, comparison between operative time, blood loss, complications, and cost was performed. Superficial parotidectomy was performed on 120 patients with the Harmonic and 54 with steel scalpel. Total parotidectomy was performed on 59 patients using the Harmonic and 22 patients with cold steel. For superficial parotidectomy, the Harmonic reduced operative time (216 ± 42 vs. 234 ± 54 min, p = 0.03) and decreased blood loss (28 ± 19 vs. 76 ± 52 mls, p Harmonic decreased operative time (240 ± 42 vs. 288 ± 78 min, p = 0.01) and reduced blood loss (38 ± 21 mls vs. 85 ± 55 mls, p Harmonic use was associated with surgical cost reduction secondary to reduced operative times. The Harmonic scalpel decreases blood loss and operating time for superficial and total parotidectomy. Shorter operative times may decrease the overall cost of parotidectomy.

  1. Pituitary Magnetic Resonance Imaging for Sellar and Parasellar Masses: Ten-Year Experience in 2598 Patients

    Science.gov (United States)

    Famini, Pouyan; Maya, Marcel M.

    2011-01-01

    Context: Sellar and parasellar masses present with overlapping clinical and radiological features ranging from asymptomatic incidental presentations and hormonal effects to compressive local mass effects. Pituitary masses are diagnosed with increased frequency with magnetic resonance imaging (MRI) advancements and availability, but indications and diagnostic outcomes of MRI screening for sellar lesions are not defined. Although pituitary adenomas are the most frequently encountered sellar mass lesions, other etiologies should be considered in the differential diagnosis of a sellar mass. Setting: The study was conducted at a tertiary pituitary center. Patients: This study was a retrospective review of 2598 subjects undergoing at least one pituitary MRI scan from 1999 to 2009. Main Outcome Measure: Prevalence and diagnosis of specific sellar and parasellar masses as screened by pituitary MRI. Results: The most common indications for pituitary imaging, excluding known mass follow-up, were for evaluation of hyperprolactinemia or hypogonadism. A normal pituitary gland was reported in 47% of subjects undergoing pituitary MRI. The most common pituitary adenomas initially identified by MRI included prolactinoma (40%), nonfunctioning adenoma (37%), and GH adenoma (13%). Nonadenomatous sellar masses accounted for 18% of visible lesions, of which the most common were Rathke's cleft cyst (19%), craniopharyngioma (15%), and meningioma (15%). Metastases accounted for 5% of nonpituitary lesions and breast cancer was the most common primary source. Conclusions: Half of all pituitary MRI scans performed in a large patient population yielded no visible lesion. Nonadenomatous pituitary lesions should be considered in the diagnosis of sellar masses observed on MRI, and a high clinical suspicion is required to exclude the presence of a nonfunctioning pituitary adenoma. PMID:21470998

  2. Immediate thoracotomy for penetrating injuries: Ten years' experience at a Dutch level I trauma center

    NARCIS (Netherlands)

    O.J.F. van Waes (Oscar); P.A. van Riet (Priscilla); E.M.M. van Lieshout (Esther); D. den Hartog (Dennis)

    2012-01-01

    textabstractBackground: An emergency department thoracotomy (EDT) or an emergency thoracotomy (ET) in the operating theater are both beneficial in selected patients following thoracic penetrating injuries. Since outcome-descriptive European studies are lacking, the aim of this retrospective study

  3. Microbiologic Data in Acute Cholecystitis: Ten Years' Experience from Bile Cultures Obtained during Percutaneous Cholecystostomy.

    Science.gov (United States)

    Nitzan, Orna; Brodsky, Yuri; Edelstein, Hana; Hershko, Dan; Saliba, Walid; Keness, Yoram; Peretz, Avi; Chazan, Bibiana

    2017-04-01

    The aim of the study was to describe the microbiology and susceptibility patterns in acute cholecystitis by examining bile culture results from patients who underwent percutaneous cholecystostomy and examine concordance with empiric treatment. A total of 124 patients with acute cholecystitis underwent percutaneous cholecystostomy between 2003 and 2012 at Emek Medical Center, Israel. Data on bile and blood culture results, isolate susceptibility, and clinical outcomes were retrieved from patient files. Bile cultures obtained from 116 patients were positive in 70 (60.3%) patients. Blood cultures obtained from 77 patients were positive in 23 (31.1%). Escherichia coli was the most common isolate in 28.6% of bile cultures and 43.5% of blood cultures. The concordance between empiric treatment coverage and culture isolate susceptibility was 67.6%. In most discordant cases, the isolates were Enterobacter spp. (40.9%) and Enterococcus spp. (31.8%). Overall, the in-hospital mortality rate was 7%: 2% in patients with concordant treatment compared with 14% in patients with discordant treatment (p = 0.09). Empiric antibiotic regimens were adequate in only two-thirds of patients. There might be a trend for poorer outcome in patients treated with inadequate antibiotic agents, emphasizing the importance of tailoring antibiotic treatment.

  4. Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients.

    Science.gov (United States)

    Famini, Pouyan; Maya, Marcel M; Melmed, Shlomo

    2011-06-01

    Sellar and parasellar masses present with overlapping clinical and radiological features ranging from asymptomatic incidental presentations and hormonal effects to compressive local mass effects. Pituitary masses are diagnosed with increased frequency with magnetic resonance imaging (MRI) advancements and availability, but indications and diagnostic outcomes of MRI screening for sellar lesions are not defined. Although pituitary adenomas are the most frequently encountered sellar mass lesions, other etiologies should be considered in the differential diagnosis of a sellar mass. The study was conducted at a tertiary pituitary center. This study was a retrospective review of 2598 subjects undergoing at least one pituitary MRI scan from 1999 to 2009. Prevalence and diagnosis of specific sellar and parasellar masses as screened by pituitary MRI. The most common indications for pituitary imaging, excluding known mass follow-up, were for evaluation of hyperprolactinemia or hypogonadism. A normal pituitary gland was reported in 47% of subjects undergoing pituitary MRI. The most common pituitary adenomas initially identified by MRI included prolactinoma (40%), nonfunctioning adenoma (37%), and GH adenoma (13%). Nonadenomatous sellar masses accounted for 18% of visible lesions, of which the most common were Rathke's cleft cyst (19%), craniopharyngioma (15%), and meningioma (15%). Metastases accounted for 5% of nonpituitary lesions and breast cancer was the most common primary source. Half of all pituitary MRI scans performed in a large patient population yielded no visible lesion. Nonadenomatous pituitary lesions should be considered in the diagnosis of sellar masses observed on MRI, and a high clinical suspicion is required to exclude the presence of a nonfunctioning pituitary adenoma.

  5. Esophageal Atresia with Tracheoesophageal Fistula: Ten Years of Experience in an Institute

    Directory of Open Access Journals (Sweden)

    Chia-Feng Yang

    2006-07-01

    Conclusion: The survival rate of the patients with EA/TEF is influenced mainly by associated life-threatening anomalies. TMS combined with a history of dying spell may be the major fatal complication.

  6. Constructed wetlands for tannery wastewater treatment in Portugal: ten years of experience.

    Science.gov (United States)

    Calheiros, Cristina S C; Rangel, António O S S; Castro, Paula M L

    2014-01-01

    Wastewaters from tannery industry are complex in composition and providing adequate treatment can be difficult. Constructed wetlands (CW) are regarded as an alternative treatment to the conventional biological systems, as a developing cost-effective and environmentally friendly phytoremediation technology. The present review compiles and integrates information on CWs technology for the needs of the tannery sector. The following issues arise as crucial for the implementation of such systems, namely i) an accurate wastewater characterization and an effective pretreatment before reaching the CW, ii) choosing the plants species better adapted to the imposed conditions, iii) substrate selection and iv) range of organic loadings applied. The examples practiced in Portugal give indication that horizontal subsurface flow systems, with expanded clay media, are a suitable option to be considered when dealing with high organic loading tannery wastewater (up to c.a. 3800 kgCODha(-1)d(-1)), being resilient to a wide range of hydraulic variations. Plants such as Phragmites and Typha have shown to be adequate for tannery wastewater depuration, with Arundo donax proving resilient to high salinity wastewaters. The flexibility of implementation allows the CW to be adapted to different sites with different configurations, being suitable as main secondary or tertiary treatment stage.

  7. Bilateral Facial Paralysis: A 13-Year Experience.

    Science.gov (United States)

    Gaudin, Robert A; Jowett, Nathan; Banks, Caroline A; Knox, Christopher J; Hadlock, Tessa A

    2016-10-01

    Bilateral facial palsy is a rare clinical entity caused by myriad disparate conditions requiring different treatment paradigms. Lyme disease, Guillain-Barré syndrome, and leukemia are several examples. In this article, the authors describe the cause, the initial diagnostic approach, and the management of long-term sequelae of bilateral paralysis that has evolved in the authors' center over the past 13 years. A chart review was performed to identify all patients diagnosed with bilateral paralysis at the authors' center between January of 2002 and January of 2015. Demographics, signs and symptoms, diagnosis, initial medical treatment, interventions for facial reanimation, and outcomes were reviewed. Of the 2471 patients seen at the authors' center, 68 patients (3 percent) with bilateral facial paralysis were identified. Ten patients (15 percent) presented with bilateral facial paralysis caused by Lyme disease, nine (13 percent) with Möbius syndrome, nine (13 percent) with neurofibromatosis type 2, five (7 percent) with bilateral facial palsy caused by brain tumor, four (6 percent) with Melkersson-Rosenthal syndrome, three (4 percent) with bilateral temporal bone fractures, two (3 percent) with Guillain-Barré syndrome, one (2 percent) with central nervous system lymphoma, one (2 percent) with human immunodeficiency virus infection, and 24 (35 percent) with presumed Bell palsy. Treatment included pharmacologic therapy, physical therapy, chemodenervation, and surgical interventions. Bilateral facial palsy is a rare medical condition, and treatment often requires a multidisciplinary approach. The authors outline diagnostic and therapeutic algorithms of a tertiary care center to provide clinicians with a systematic approach to managing these complicated patients.

  8. Ten-Year Trends (1999–2010) of Adherence to the Mediterranean Diet among the Balearic Islands’ Adult Population

    Science.gov (United States)

    Bibiloni, Maria del Mar; González, Mónica; Julibert, Alicia; Llompart, Isabel

    2017-01-01

    The aim of this work was to assess ten-year trends (1999–2010) of adherence to the Mediterranean dietary pattern (MDP) among the Balearic Islands’ adult population. Two independent cross-sectional dietary surveys (1999–2000, n = 1200 and 2009–2010 n = 1388, including participants aged 16–65 years) were carried out in the Balearic Islands, Spain. Dietary habits were assessed by means of two 24 h diet recalls and a validated semi-quantitative food-frequency questionnaire that covers 145 food items. Adherence to the MDP was defined according to a score constructed considering the consumption of nine MDP characteristic components: high monounsaturated fatty acids:saturated fatty acids (MUFA:SFA) ratio, moderate ethanol consumption, high legumes, cereals and roots, fruits, vegetables, and fish consumption, and low consumption of meat and milk. Socio-economic status, education level, lifestyle factors and health status were also assessed. Adherence to the MDP was 43.1% (SD 5.8) in 1999–2000 and 44.6% (SD 8.3) in 2009–2010. Higher age was directly associated with higher adherence to the MDP, and this association was stronger in males than in females. Young generations and smokers showed the lowest adherence to MDP, whereas people with higher educational and socio-economic level, and who were physically active showed the highest adherence. According to the place of birth, the increase in the percentage of the adherence to the MDP was observed to be smaller among the Balearic Island’s natives than among people born abroad. In 2009–2010, individuals in the MDP’s fourth quartile were more likely to be older (aged 46–65 years), and were less likely to have a low occupational level, to have a light physical activity level and to be smoker than in 1999–2000. The adherence to the MDP has been stabilized and slightly recovered among the Balearic Islands’ adult population in the last decade. PMID:28708083

  9. Increasing trends of diabetes mellitus and body weight: a ten year observation at gondar university teaching referral hospital, northwest ethiopia.

    Science.gov (United States)

    Abebe, Solomon Mekonnen; Berhane, Yemane; Worku, Alemayehu; Alemu, Shitay

    2013-01-01

    Diabetes mellitus is becoming one of the major causes of premature adult mortality in developing countries. However, there is a very little documentation of the morbidity trend in such countries. To assess the ten-year trend of diabetes mellitus at Gondar University Teaching Referral Hospital, northwest Ethiopia. A hospital-based retrospective record review was done at the main referral hospital in northwest Ethiopia. Data were obtained from medical records of all registered diabetic patients in the Diabetic Follow up Clinic between 2000 and 2009. An Extended Mantel-Haenzel chi-square test for the linear trend was used to examine the trend over time. Out of the total 354,524 patients who visited the Outpatient Department of the hospital during the study period, 1553 (4.4/1000) were diabetes patients, of which 50.1% was type 1 and 49.9% type 2 diabetes mellitus. The average increase in the proportion of both Type 1 and Type 2 diabetes mellitus cases between 2000 and 2009 was 125%. The mean (±SD) age for Type 1 diabetes mellitus was 29.1 (±12), and 53.5 (±12) for Type 2 diabetes. Overall 42.5% of the diabetes mellitus patients were female and 31.7% were rural residents. The mean body mass index for both type of diabetes mellitus increased from 15.9 to 18.3 kg for type 1 and from 23.8 to 24.6 for type 2 between 2000 and 2009, respectively. The number of diabetes mellitus cases seen at Gondar Referral Hospital is rising steadily. A comprehensive diabetes prevention, treatment, and care program is needed to improve the quality of life of the increasing diabetes mellitus cases in Ethiopia.

  10. Monitoring of Pb exposure in waterfowl ten years after a mine spill through the use of noninvasive sampling.

    Directory of Open Access Journals (Sweden)

    Monica Martinez-Haro

    Full Text Available Lead exposure in waterfowl was studied using noninvasive fecal sampling in the Guadalquivir Marshes in Spain, an area affected by the 1998 Aznalcóllar mine disaster. Feces of greylag geese (Anser anser, n = 191 and purple gallinule (Porphyrio porphyrio, n = 91 were collected from three different impacted sites (Entremuros, Caracoles and Cerro de los Ánsares during the winters of 2004 to 2008. Lead and aluminium (an indicator of sediment ingestion and Pb isotope signatures (to discriminate between sources of Pb exposure were analyzed in freeze-dried, acid digested samples. The concentrations of fecal porphyrins and biliverdin were determined as noninvasive biomarkers to study Pb exposure effects. Results showed a decrease in Pb exposure over time in wintering greylag geese. In contrast, for purple gallinule resident in the Entremuros a clear trend was not evident. For both species, sediment ingestion appeared to be the main source of exposure to Pb. In the Entremuros, some samples from purple gallinule were detected with higher Pb levels than expected for simple soil ingestion, and these had Pb isotopic profiles compatible with mining sludge or Pb shot. Whilst fecal Pb isotopic profiles were effective in differentiating between samples from sites with different levels and sources of pollution, the combined use of element ratios (such as Pb/Al and other non-traditional stable isotope signatures may also prove worthwhile. Overall, the fecal Pb levels detected were below those described in feces for waterfowl from other uncontaminated areas(<10 µg/g d.w.. Despite this, for both species fecal Pb levels were positively correlated with porphyrin excretion, and for purple gallinule, with the coproporphyrin III/I ratio, suggesting some subtle effects on heme synthesis in birds. Ten years after the mine spill, Pb contamination in birds by this pollution source was still detectable and subtlethal effects may persist.

  11. Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile--updated 2013.

    Science.gov (United States)

    Kishi, Reiko; Kobayashi, Sachiko; Ikeno, Tamiko; Araki, Atsuko; Miyashita, Chihiro; Itoh, Sachiko; Sasaki, Seiko; Okada, Emiko; Kobayashi, Sumitaka; Kashino, Ikuko; Itoh, Kumiko; Nakajima, Sonomi

    2013-11-01

    The Hokkaido Study on Environment and Children's Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infectious diseases and neurodevelopmental disorders and perform longitudinal observations of the children's physical development to clarify the causal relationship between these outcomes and environmental chemicals; third, to identify individuals genetically susceptible to environmental chemicals; finally, to identify the additive effects of various environmental factors in our daily life, such as secondhand smoke exposure or low folate intake during early pregnancy. In this paper, we introduce our recent progress in the Hokkaido study with a cohort profile updated in 2013. For the last ten years, we followed pregnant women and their offspring, measuring various environmental chemicals, i.e., PCB, OH-PCB and dioxins, PFCs (Perfluorinated Compounds), Organochlorine pesticides, Phthalates, bisphenol A and mercury. We discovered that the concentration of toxic equivalents (TEQ) of dioxin and other specific congeners of PCDF or PCDD have effects on birth weight, infants' neurodevelopment and immune function. There were significant gender differences in these effects; our results suggest that male infants have more susceptibility to those chemical exposures than female infants. Interestingly, we found maternal genetic polymorphisms in AHR, CYP1A1 or GSTs that significantly modified the dioxin concentrations in maternal blood, suggesting different dioxin accumulations in the bodies of individuals with these genotypes, which would lead to different dioxin exposure levels. These genetic

  12. A ten-year global record of absorbing aerosols above clouds from OMI's near-UV observations

    Science.gov (United States)

    Jethva, Hiren; Torrres, Omar; Ahn, Changwoo

    2016-05-01

    Aerosol-cloud interaction continues to be one of the leading uncertain components of climate models, primarily due to the lack of an adequate knowledge of the complex microphysical and radiative processes associated with the aerosolcloud system. The situations when aerosols and clouds are found in the same atmospheric column, for instance, when light-absorbing aerosols such as biomass burning generated carbonaceous particles or wind-blown dust overlay low-level cloud decks, are commonly found over several regional of the world. Contrary to the cloud-free scenario over dark surface, for which aerosols are known to produce a net cooling effect (negative radiative forcing) on climate, the overlapping situation of absorbing aerosols over cloud can potentially exert a significant level of atmospheric absorption and produces a positive radiative forcing at top-of-atmosphere. The magnitude of direct radiative effects of aerosols above cloud depends directly on the aerosol loading, microphysical-optical properties of the aerosol layer and the underlying cloud deck, and geometric cloud fraction. We help in addressing this problem by introducing a novel product of optical depth of absorbing aerosols above clouds retrieved from near-UV observations made by the Ozone Monitoring Instrument (OMI) on board NASA's Aura platform. The presence of absorbing aerosols above cloud reduces the upwelling radiation reflected by cloud and produces a strong `color ratio' effect in the near-UV region, which can be unambiguously detected in the OMI measurements. Physically based on this effect, the OMACA algorithm retrieves the optical depths of aerosols and clouds simultaneously under a prescribed state of atmosphere. The algorithm architecture and results from a ten-year global record including global climatology of frequency of occurrence and above-cloud aerosol optical depth, and a discussion on related future field campaigns are presented.

  13. Ten-year hemoglobin A1c trajectories and outcomes in type 2 diabetes mellitus: The Diabetes & Aging Study.

    Science.gov (United States)

    Laiteerapong, Neda; Karter, Andrew J; Moffet, Howard H; Cooper, Jennifer M; Gibbons, Robert D; Liu, Jennifer Y; Gao, Yue; Huang, Elbert S

    2017-01-01

    To classify trajectories of long term HbA1c values in patients after diagnosis of type 2 diabetes and examine each trajectory's associations with subsequent microvascular and macrovascular events and mortality. A longitudinal follow-up of 28,016 patients newly diagnosed with type 2 diabetes was conducted. Latent growth mixture modeling was used to identify ten-year HbA1c trajectories. Cox proportional hazards models were used to assess how HbA1c trajectories were associated with events (microvascular and macrovascular) and mortality. We identified 5 HbA1c trajectories: "low stable" (82.5%), "moderate increasing late" (5.1%), "high decreasing early" (4.9%), "moderate peaking late" (4.1%) and "moderate peaking early" (3.3%). After adjusting for average HbA1c, compared to the low stable trajectory, all non-stable trajectories were associated with higher incidences of microvascular events (hazard ratio (HR) range, 1.28 (95% CI, 1.08-1.53) (high decreasing early) to 1.45 (95% CI, 1.20-1.75) (moderate peaking early)). The high decreasing early trajectory was associated with an increased mortality risk (HR, 1.27 (95% CI, 1.03-1.58)). Trajectories were not associated with macrovascular events. Non-stable HbA1c trajectories were associated with greater risk of microvascular events and mortality. These findings suggest a potential benefit of early diabetes detection, prioritizing good glycemic control, and maintaining control over time. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. A Ten-Year Global Record of Absorbing Aerosols Above Clouds from OMI's Near-UV Observations

    Science.gov (United States)

    Jethva, Hiren; Torres, Omar; Ahn, Changwoo

    2016-01-01

    Aerosol-cloud interaction continues to be one of the leading uncertain components of climate models, primarily due to the lack of an adequate knowledge of the complex microphysical and radiative processes associated with the aerosol-cloud system. The situations when aerosols and clouds are found in the same atmospheric column, for instance, when light-absorbing aerosols such as biomass burning generated carbonaceous particles or wind-blown dust overlay low-level cloud decks, are commonly found over several regional of the world. Contrary to the cloud-free scenario over dark surface, for which aerosols are known to produce a net cooling effect (negative radiative forcing) on climate, the overlapping situation of absorbing aerosols over cloud can potentially exert a significant level of atmospheric absorption and produces a positive radiative forcing at top-of-atmosphere. The magnitude of direct radiative effects of aerosols above cloud depends directly on the aerosol loading, microphysical-optical properties of the aerosol layer and the underlying cloud deck, and geometric cloud fraction. We help in addressing this problem by introducing a novel product of optical depth of absorbing aerosols above clouds retrieved from near-UV observations made by the Ozone Monitoring Instrument (OMI) on board NASA's Aura platform. The presence of absorbing aerosols above cloud reduces the upwelling radiation reflected by cloud and produces a strong 'color ratio' effect in the near-UV region, which can be unambiguously detected in the OMI measurements. Physically based on this effect, the OMACA algorithm retrieves the optical depths of aerosols and clouds simultaneously under a prescribed state of atmosphere. The algorithm architecture and results from a ten-year global record including global climatology of frequency of occurrence and above-cloud aerosol optical depth, and a discussion on related future field campaigns are presented.

  15. Monitoring of Pb Exposure in Waterfowl Ten Years after a Mine Spill through the Use of Noninvasive Sampling

    Science.gov (United States)

    Martinez-Haro, Monica; Taggart, Mark A.; Lefranc, Hugues; Martín-Doimeadiós, Rosa C.; Green, Andy J.; Mateo, Rafael

    2013-01-01

    Lead exposure in waterfowl was studied using noninvasive fecal sampling in the Guadalquivir Marshes in Spain, an area affected by the 1998 Aznalcóllar mine disaster. Feces of greylag geese (Anser anser, n = 191) and purple gallinule (Porphyrio porphyrio, n = 91) were collected from three different impacted sites (Entremuros, Caracoles and Cerro de los Ánsares) during the winters of 2004 to 2008. Lead and aluminium (an indicator of sediment ingestion) and Pb isotope signatures (to discriminate between sources of Pb exposure) were analyzed in freeze-dried, acid digested samples. The concentrations of fecal porphyrins and biliverdin were determined as noninvasive biomarkers to study Pb exposure effects. Results showed a decrease in Pb exposure over time in wintering greylag geese. In contrast, for purple gallinule resident in the Entremuros a clear trend was not evident. For both species, sediment ingestion appeared to be the main source of exposure to Pb. In the Entremuros, some samples from purple gallinule were detected with higher Pb levels than expected for simple soil ingestion, and these had Pb isotopic profiles compatible with mining sludge or Pb shot. Whilst fecal Pb isotopic profiles were effective in differentiating between samples from sites with different levels and sources of pollution, the combined use of element ratios (such as Pb/Al) and other non-traditional stable isotope signatures may also prove worthwhile. Overall, the fecal Pb levels detected were below those described in feces for waterfowl from other uncontaminated areas(Pb levels were positively correlated with porphyrin excretion, and for purple gallinule, with the coproporphyrin III/I ratio, suggesting some subtle effects on heme synthesis in birds. Ten years after the mine spill, Pb contamination in birds by this pollution source was still detectable and subtlethal effects may persist. PMID:23437364

  16. First year clinical tutorials: students' learning experience.

    Science.gov (United States)

    Burgess, Annette; Oates, Kim; Goulston, Kerry; Mellis, Craig

    2014-01-01

    Bedside teaching lies at the heart of medical education. The learning environment afforded to students during clinical tutorials contributes substantially to their knowledge, thinking, and learning. Situated cognition theory posits that the depth and breadth of the students' learning experience is dependent upon the attitude of the clinical teacher, the structure of the tutorial, and the understanding of tutorial and learning objectives. This theory provides a useful framework to conceptualize how students' experience within their clinical tutorials impacts their knowledge, thinking, and learning. The study was conducted with one cohort (n=301) of students who had completed year 1 of the medical program at Sydney Medical School in 2013. All students were asked to complete a three-part questionnaire regarding their perceptions of their clinical tutor's attributes, the consistency of the tutor, and the best features of the tutorials and need for improvement. Both quantitative and qualitative data were collected and analyzed using descriptive statistics. The response rate to the questionnaire was 88% (265/301). Students perceived that their tutors displayed good communication skills and enthusiasm, encouraged their learning, and were empathetic toward patients. Fifty-two percent of students reported having the same communications tutor for the entire year, and 28% reported having the same physical examination tutor for the entire year. Students would like increased patient contact, greater structure within their tutorials, and greater alignment of teaching with the curriculum. Situated cognition theory provides a valuable lens to view students' experience of learning within the clinical environment. Our findings demonstrate students' appreciation of clinical tutors as role models, the need for consistency in feedback, the importance of structure within tutorials, and the need for tutors to have an understanding of the curriculum and learning objectives for each

  17. Ten-Year Follow-Up of Desarthrodesis of the Knee Joint 41 Years after Original Arthrodesis for a Bone Tumor

    Directory of Open Access Journals (Sweden)

    Ahmed Hamed Kassem Abdelaal

    2015-01-01

    Full Text Available Introduction. The main indication for knee arthrodesis in tumor surgery is a tumor that requires an extensive resection in which the joint surface cannot be preserved. We report a patient that had knee desarthrodesis 41 years after giant cell tumor resection followed by a knee arthrodesis. This is the longest reported follow-up after desarthrodesis and conversion to total knee arthroplasty (TKA, almost ten years. Case Report. A 71-year-old man with a distal femoral giant cell tumor had undergone a resection of the distal femur and knee arthrodesis using Kuntscher nail in 1962. In July 2003 he experienced gradually increasing pain of his left knee. We performed a desarthrodesis and conversion to TKA in 2005. The postoperative period passed uneventfully as his pain and gait improved, with gradually increasing range of motion (ROM and no infection. He now walks independently, with no brace or contractures. Conclusion. Desarthrodesis of the knee joint and conversion to TKA are a difficult surgical choice with a high complication risk. However, our patient’s life style has improved, he has no pain, and he can ascend and descend stairs more easily. The surgeon has to be very meticulous in selecting a patient for knee arthrodesis and counseling them to realize that their expectations may not be achievable.

  18. Ten-Year Follow-Up of Desarthrodesis of the Knee Joint 41 Years after Original Arthrodesis for a Bone Tumor.

    Science.gov (United States)

    Kassem Abdelaal, Ahmed Hamed; Yamamoto, Norio; Hayashi, Katsuhiro; Takeuchi, Akihiko; Miwa, Shinji; Inatani, Hiroyuki; Tsuchiya, Hiroyuki

    2015-01-01

    Introduction. The main indication for knee arthrodesis in tumor surgery is a tumor that requires an extensive resection in which the joint surface cannot be preserved. We report a patient that had knee desarthrodesis 41 years after giant cell tumor resection followed by a knee arthrodesis. This is the longest reported follow-up after desarthrodesis and conversion to total knee arthroplasty (TKA), almost ten years. Case Report. A 71-year-old man with a distal femoral giant cell tumor had undergone a resection of the distal femur and knee arthrodesis using Kuntscher nail in 1962. In July 2003 he experienced gradually increasing pain of his left knee. We performed a desarthrodesis and conversion to TKA in 2005. The postoperative period passed uneventfully as his pain and gait improved, with gradually increasing range of motion (ROM) and no infection. He now walks independently, with no brace or contractures. Conclusion. Desarthrodesis of the knee joint and conversion to TKA are a difficult surgical choice with a high complication risk. However, our patient's life style has improved, he has no pain, and he can ascend and descend stairs more easily. The surgeon has to be very meticulous in selecting a patient for knee arthrodesis and counseling them to realize that their expectations may not be achievable.

  19. Ten Years HIV Free: An Interview with “The Berlin Patient,” Timothy Ray Brown

    Directory of Open Access Journals (Sweden)

    Michael M. Lederman

    2017-11-01

    Full Text Available It was just about 10 years ago that Timothy Ray Brown was cured of HIV infection by receiving bone marrow stem cell transplantations from an HLA matched donor who also was homozygous for the CCR5 delta 32 mutation that renders immune cells resistant to infection by most HIV viruses. During an October 2017 visit to Cleveland to help launch a number of clinical trials targeting the Cure, Timothy sat down with Pathogens and Immunity editor Michael Lederman and community activist Earl Pike to talk about his experiences.

  20. Ten years of health workforce planning in the Netherlands: a tentative evaluation of GP planning as an example

    Directory of Open Access Journals (Sweden)

    Van Greuningen Malou

    2012-08-01

    Full Text Available Abstract Introduction In many countries, health-care labour markets are constantly being challenged by an alternation of shortage and oversupply. Avoiding these cyclic variations is a major challenge. In the Netherlands, a workforce planning model has been used in health care for ten years. Case description Since 1970, the Dutch government has explored different approaches to determine the inflow in medical schools. In 2000, a simulation model for health workforce planning was developed to estimate the required and available capacity of health professionals in the Netherlands. In this paper, this model is explained, using the Dutch general practitioners as an example. After the different steps in the model are clarified, it is shown how elements can be added to arrive at different versions of the model, or ‘scenarios’. A comparison is made of the results of different scenarios for different years. In addition, the subsequent stakeholder decision-making process is considered. Discussion and evaluation Discussion of this paper shows that workforce planning in the Netherlands is a complex modelling task, which is sensitive to different developments influencing the balance between supply and demand. It seems plausible that workforce planning has resulted in a balance between supply and demand of general practitioners. Still, it remains important that the modelling process is accepted by the different stakeholders. Besides calculating the balance between supply and demand, there needs to be an agreement between the stakeholders to implement the advised training inflow. The Dutch simulation model was evaluated using six criteria to be met by models suitable for policy objectives. This model meets these criteria, as it is a comprehensive and parsimonious model that can include all relevant factors. Conclusion Over the last decade, health workforce planning in the Netherlands has become an accepted instrument for calculating the required supply of

  1. Final year students' experiences of the Bachelor of Midwifery course.

    Science.gov (United States)

    Carolan-Olah, Mary; Kruger, Gina; Walter, Ruby; Mazzarino, Melissa

    2014-05-01

    : the aim of the study was to explore the experiences of final year Bachelor of Midwifery students. earlier research indicates that midwifery students experience a number of difficulties and concerns during their studentship. These difficulties can lead to a lack of confidence and poorer integration and socialisation into the profession. Ultimately, poorer integration may lead to dissatisfaction and attrition from the profession. a qualitative approach, informed by interpretative phenomenological analysis (IPA), was used in this study. Ten completing Bachelor of Midwifery students participated in in-depth interviews and reflected on their experiences over their three year course. Data were subjected to IPA analytic steps as proposed by Smith and Osborn (2008). demographics revealed that participants were generally aged more than 35 years and worked 16 hours or less per week. Most had two or more children and lived with a spouse/partner. Four main themes emerged from the analysis: (1) a challenging start; (2) coming to terms with course requirements; (3) developing strategies; and (4) overall satisfaction with the course. Participants generally considered that their individual strengths and determination helped them to negotiate the many challenges they encountered during the course. this study indicates that students undergo a process of adjustment as they travel through the Bachelor of Midwifery course. The most critical transition phase appears to occur in the first year and students may require additional supports to assist their socialisation into both the university and their course. Particular needs identified include return to study skills for mature-aged students and counselling and support group needs generally. The provision of such supports may assist with the retention of students within the course and may contribute to overall student satisfaction. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Factors associated with severe malaria among children below ten years in Mutasa and Nyanga districts, Zimbabwe, 2014-2015.

    Science.gov (United States)

    Mutsigiri-Murewanhema, Faith; Mafaune, Patron Trish; Shambira, Gerald; Juru, Tsitsi; Bangure, Donewell; Mungati, More; Gombe, Notion Tafara; Tshimanga, Mufuta

    2017-01-01

    Severe malaria is a rare life threatening illness. Only a small proportion of patients with clinical malaria progress to this medical emergency. On reviewing 61 malaria death investigation forms submitted to the provincial office in 2014, 22(36%) were children below ten years who succumbed to severe malaria. Mutasa and Nyanga Districts reported 73% of these deaths. This study was conducted to determine factors associated with severe malaria so as to come up with evidence based interventions to prevent severe malaria and associated mortality. A 1:2 unmatched case control study was conducted. A case was defined as a child 10 years and below, who was admitted at Hauna (Mutasa) or Nyanga District Hospitals between September 2014 and May 2015 with a primary diagnosis of severe malaria. Controls were children of similar age with uncomplicated malaria. Permission to conduct the study was sought and granted by the Medical Research Council of Zimbabwe (Approval number B/874), Joint Research Ethics Committee, Health Studies Office and the Manicaland Directorate Institutional Review Board. Written informed consent was sought from all caregivers of enrolled children. Interviewer administered questionnaires were used to ascertain exposures. A total of 52 cases and 104 controls were enrolled into the study. The median age of cases was 4 years (Q1=3, Q3=9) and 6 years for controls (Q1=3, Q3=8). The Case Fatality Rate among cases was 28.8%. The independent risk factors for severe malaria were; distance >10km to the nearest health facility [Adjusted Odds Ratio (aOR)=14.35, 95% CI=1.30, 158.81], duration of symptoms before seeking medical care >2 days [aOR=9.03, 95% CI=2.21, 36.93], having comorbidities [aOR=5.38, 95% CI=1.90, 15.19], staying in a house under construction [aOR=4.51, 95%CI=1.80, 11.32] and duration of illness before receiving antimalarial medicines >24 hours [aOR=3.82, 95% CI=1.44, 10.12]. Owning at least one ITN in the household [aOR=0.32, 95% CI=0.11, 0.95] and

  3. Ten years′ experience with adjuvant intravesical immunotherapy in management of superficial transitional cell carcinoma of urinary bladder - a review

    Directory of Open Access Journals (Sweden)

    N K Mohanty

    2001-01-01

    The author reviews his experience of 10 years in man-agement of these malignancies with intravesical immu-notherapy and concludes that a low dose BCG (60mg with Interferon α-2b (5 million IU has shown to be very effective in reducing tumor recurrences, prolonging dis-ease-progression-free interval with a very low toxicity in such patients. To achieve this a periodic maintenance dose therapy is absolutely necessary.

  4. First year clinical tutorials: students’ learning experience

    Directory of Open Access Journals (Sweden)

    Burgess A

    2014-11-01

    Full Text Available Annette Burgess,1 Kim Oates,2 Kerry Goulston,2 Craig Mellis1 1Central Clinical School, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; 2Sydney Medical School, The University of Sydney, Sydney, NSW, Australia Background: Bedside teaching lies at the heart of medical education. The learning environment afforded to students during clinical tutorials contributes substantially to their knowledge, thinking, and learning. Situated cognition theory posits that the depth and breadth of the students' learning experience is dependent upon the attitude of the clinical teacher, the structure of the tutorial, and the understanding of tutorial and learning objectives. This theory provides a useful framework to conceptualize how students' experience within their clinical tutorials impacts their knowledge, thinking, and learning. Methods: The study was conducted with one cohort (n=301 of students who had completed year 1 of the medical program at Sydney Medical School in 2013. All students were asked to complete a three-part questionnaire regarding their perceptions of their clinical tutor's attributes, the consistency of the tutor, and the best features of the tutorials and need for improvement. Both quantitative and qualitative data were collected and analyzed using descriptive statistics. Results: The response rate to the questionnaire was 88% (265/301. Students perceived that their tutors displayed good communication skills and enthusiasm, encouraged their learning, and were empathetic toward patients. Fifty-two percent of students reported having the same communications tutor for the entire year, and 28% reported having the same physical examination tutor for the entire year. Students would like increased patient contact, greater structure within their tutorials, and greater alignment of teaching with the curriculum. Conclusion: Situated cognition theory provides a valuable lens to view students' experience of learning within the

  5. [Bilateral renal agenesis: a 10-year experience].

    Science.gov (United States)

    Viñals, F; Sepúlveda, W H; Klaasen, R; Ciuffardi, I; Donetch, G

    1992-01-01

    Bilateral renal agenesis (BRA) is an uniformly lethal malformation occurring in 0.1-0.3/1000 births. This condition is associated with severe oligohydramnios, intrauterine growth retardation (IUGR), extra-renal anomalies, and malpresentation. The aim of this study was to present our experience with 10 cases of BRA seen in a 10-year period. In only one case the prenatal diagnosis was made. Therefore, the clinician was faced with a high-risk pregnancy: 70% of cases presented with malpresentation, oligohydramnios, and severe IUGR. This explain the high rate of cesarean section (40%) and the neonatal intensive care offered to these neonates. The principal methods to improve the prenatal diagnosis of this condition are discussed.

  6. Is severe early childhood caries predictive of caries and fluorosis in permanent teeth? Ten-year follow-up

    Directory of Open Access Journals (Sweden)

    Danila Lorena NUNES-DOS-SANTOS

    2017-05-01

    Full Text Available Abstract Introduction Severe early childhood caries is defined as the presence of any sign of decay in children younger than three years. Objective This retrospective longitudinal observational study investigated caries and fluorosis in children with S-ECC from a city with fluoridated water. Material and method We included children under the age of three years who followed a maternal and child dental care program between the years of 1997 and 2003. The children were divided into 2 groups: group 1 (S-ECC and group 2 (no caries. Guardians were contacted by telephone or mail. Caregivers completed questionnaire on socio-demographic and behavioral variables. The clinical dental examinations were performed in a dental clinic to assess caries experience and dental fluorosis. Multiple linear regression was used to determine factors associated with DMFT, and multivariate analysis by multiple logistic regression was used to determine the possible independent factors associated with the occurrence of fluorosis. Result The sample consisted of 126 patients aged 8-12 years, of whom 52.4% were male. The presence of S-ECC increased the DMFT by an average of 0.84 (p = 0.02. Both the frequency of tooth brushing and the use of standard toothpaste were protective factors from the development of caries in the permanent dentition (p <0.05. Parents who reported that their children refused to brush their teeth had 70% less chance of developing fluorosis (p = 0.02. Conclusion The presence of S-ECC was a risk factor for the development of caries in the permanent dentition, but not for the development of fluorosis.

  7. Students' Constitutional Right to a Sound Basic Education: New York State's Unfinished Agenda. Part 1. A Roadmap to Constitutional Compliance Ten Years after "CFE v. State"

    Science.gov (United States)

    Rebell, Michael A.; Wolff, Jessica R.

    2016-01-01

    Ten years have passed since New York's highest court ruled in the landmark school-funding and educational-rights case, "Campaign for Fiscal Equity (CFE) v. State of New York," that the state was violating students' constitutional right to the "opportunity for a sound basic education" and ordered significant reforms of the…

  8. The ten-year course of depression in primary care and long-term effects of psychoeducation, psychiatric consultation and cognitive behavioral therapy

    NARCIS (Netherlands)

    Conradi, Henk Jan; Bos, Elisabeth H; Kamphuis, Jan H; de Jonge, Peter

    BACKGROUND: While the majority of depressed patients are treated in primary care, long-term follow-up data on the naturalistic course of depression and treatment effectiveness in this setting are scarce. This study examined the ten-year course of depression in primary care patients who had

  9. Let Book Joy Begin @ Your Library[R]!: Ten Years of El Dia de los Ninos/El Dia de los Libros

    Science.gov (United States)

    Roy, Loriene

    2007-01-01

    Ten years ago, in 1996, poet and children's book author, Pat Mora began celebrating "book joy" by founding a children's book and reading day, El Dia de los Ninos/El Dia de los Libros or Children's Day/Book Day. Dia is modeled on National Children's Day Celebrations in Mexico held since 1925 when it was launched in conjunction with a…

  10. The Impact of Oral Training on Argumentative Texts Produced by Ten- and Eleven-Year-Old Children: Exploring the Relation between Narration and Argumentation.

    Science.gov (United States)

    Auriac-Peyronnet, Emmanuele

    2001-01-01

    Presents the results of a study that trained ten and eleven year old children to improve their argumentative abilities. Explores whether didactic sequence with oral exercises and co-operative oral debate affected the children. Explains that the children were required to produce three argumentative texts before and after each training phase. (CMK)

  11. Foreign bodies in upper gastrointestinal tract and urgent endoscopic interventions – review of a ten-year period

    Directory of Open Access Journals (Sweden)

    Pavel Skok

    2005-07-01

    Full Text Available Background: Foreign bodies in the upper digestive tube are rarely the cause of an urgent condition in gastroenterology. They usually enter the digestive tube during nutrition or by mistake. However, certain groups of the population such as convicts or psychiatric patients tend to swallow them intentionally. The authors aim was to assess the percentage of patients in which urgent endoscopic investigation revealed true foreign bodies in the upper digestive tube, to evaluate the success of endoscopic procedures and the resolution of eventual complications.Patients and methods: The study includes patients in which urgent endoscopic investigations of the upper digestive tract were performed in a 10-year period (1 January 1994 to 31 December 2003.Results: Altogether 6416 patients were investigated, mean age 59.3 years, SD ± 17.2 years, range 1–106 years, 2452 females and 3964 males. In 51 patients, 0.8% of all subjects, foreign bodies were detected in the esophagus or stomach. In these patients a total of 65 endoscopic investigations were performed, in 94% the foreign bodies were removed endoscopically (48/51 patients, in three cases the endoscopic procedures were not successful. Among the foreign bodies removed were various metal or plastic objects: coins, keys, screws, hooks, batteries, razor blades, needles, parts of kitchen, toilet or writing utensils, lighters, buttons, toys, a toothbrush as well as impacted pieces of bone. In the patients with successful endoscopic removal of the objects, no significant complications were noted. In 3 patients (3/48, 6.3% only mild hemorrhages from the region of the esophagogastric junction were observed.Conclusions: The technological development of endoscopic instruments made it possible to carry out different therapeutic procedures. The method has proved successful in removing foreign bodies from the upper digestive tube. Various factors affect the success of the procedure, the more important being adequate

  12. Ten-year follow-up study of three alternative bearing surfaces used in total hip arthroplasty in young patients: a prospective randomised controlled trial.

    Science.gov (United States)

    Atrey, A; Ward, S E; Khoshbin, A; Hussain, N; Bogoch, E; Schemitsch, E H; Waddell, J P

    2017-12-01

    We present the ten-year data of a cohort of patients, aged between 18 and 65 years (mean age 52.7 years; 19 to 64), who underwent total hip arthroplasty. Patients were randomised to be treated with a cobalt-chrome (CoCr) femoral head with an ultra-high molecular weight polyethylene (UHMWPE), highly cross-linked polyethylene (XLPE) or ceramic-on-ceramic (CoC) bearing surface. A total of 102 hips (91 patients) were randomised into the three groups. At ten years, 97 hips were available for radiological and functional follow-up. Two hips (two patients) had been revised (one with deep infection and one for periprosthetic fracture) and three were lost to follow-up. Radiological analysis was performed using a validated digital assessment programme to give linear, directional and volumetric wear of the two polyethylene groups. There was a significantly reduced rate of steady-state linear wear with XLPE (0.07 mm/yr) compared with UHMWPE (0.37 mm/yr) (p = 0.001). Volumetric wear was also significantly reduced in the XLPE group (29.29 mm 3 /yr) compared with the UHMWPE group (100.75mm 3 /yr) (p = 0.0001). There were six patients with UHMWPE who had non-progressive osteolysis and none in the XLPE group. All three bearing groups had significant improvements in 12-item short form health survey scores, Western Ontario and McMaster Universities Osteoarthritis Index score and Harris Hip Score. However, the improvement in HSS was significantly less in the UHMWPE group (p = 0.0188) than in the other two groups. At ten years, the rates of volumetric and linear wear in the XLPE group remain low and predominantly below the estimated threshold for osteolysis (1 mm/yr). The rate of linear wear in the XLPE group was three times less than in the UHMWPE group at five-year follow-up and five times less at ten years. The rate of volumetric wear was also three times less in the XLPE group at ten years. While CoC also performs well, XLPE at ten years remains a safe and excellent bearing option

  13. Childhood and adult tuberculosis in a rural hospital in Southeast Ethiopia: a ten-year retrospective study.

    Science.gov (United States)

    Ramos, Jose Manuel; Reyes, Francisco; Tesfamariam, Abraham

    2010-04-27

    Many DOTS experiences in developing countries have been reported. However, experience in a rural hospital and information on the differences between children and adults are limited. We described the epidemiology and treatment outcome of adult and childhood tuberculosis (TB) cases, and identified risk factors associated with defaulting and dying during TB treatment in a rural hospital over a 10-year period (1998 to 2007). Retrospective data collection using TB registers and treatment cards in a rural private mission hospital. Information was collected on number of cases, type of TB and treatment outcomes using standardised definitions. 2225 patients were registered, 46.3% of whom were children. A total of 646 patients had smear-positive pulmonary TB (PTB), [132 (20.4%) children]; 816 had smear-negative PTB [556 (68.2%) children], and 763 extra-PTB (EPTB) [341 (44.8%) children]. The percentage of treatment defaulters was higher in paediatric (13.9%) than in adult patients (9.3%) (p = 0.001). The default rate declined from 16.8% to 3.5%, and was independently positively associated with TB meningitis (AOR: 2.8; 95% CI: 1.2-6.6) and negatively associated with smear-positive PTB (AOR: 0.6; 95% CI: 0.4-0.8). The mortality rate was 5.3% and the greatest mortality was associated with adult TB (AOR: 1.7; 95% CI: 1.1-2.5), TB meningitis (AOR: 3.6; 95% CI:1.2-10.9), and HIV infection (AOR: 4.3; 95% CI: 1.9-9.4). Decreased mortality was associated with TB lymphadenitis (AOR: 0.24; 95% CI: 0.11-0.57). (1) The registration of TB cases can be useful to understand the epidemiology of TB in local health facilities. (2) The defaulter and mortality rate of childhood TB is different to that of adult TB. (3) The rate of defaulting from treatment has declined over time.

  14. Childhood and adult tuberculosis in a rural hospital in Southeast Ethiopia: a ten-year retrospective study

    Directory of Open Access Journals (Sweden)

    Ramos Jose

    2010-04-01

    Full Text Available Abstract Background Many DOTS experiences in developing countries have been reported. However, experience in a rural hospital and information on the differences between children and adults are limited. We described the epidemiology and treatment outcome of adult and childhood tuberculosis (TB cases, and identified risk factors associated with defaulting and dying during TB treatment in a rural hospital over a 10-year period (1998 to 2007. Methods Retrospective data collection using TB registers and treatment cards in a rural private mission hospital. Information was collected on number of cases, type of TB and treatment outcomes using standardised definitions. Results 2225 patients were registered, 46.3% of whom were children. A total of 646 patients had smear-positive pulmonary TB (PTB, [132 (20.4% children]; 816 had smear-negative PTB [556 (68.2% children], and 763 extra-PTB (EPTB [341 (44.8% children]. The percentage of treatment defaulters was higher in paediatric (13.9% than in adult patients (9.3% (p = 0.001. The default rate declined from 16.8% to 3.5%, and was independently positively associated with TB meningitis (AOR: 2.8; 95% CI: 1.2-6.6 and negatively associated with smear-positive PTB (AOR: 0.6; 95% CI: 0.4-0.8. The mortality rate was 5.3% and the greatest mortality was associated with adult TB (AOR: 1.7; 95% CI: 1.1-2.5, TB meningitis (AOR: 3.6; 95% CI:1.2-10.9, and HIV infection (AOR: 4.3; 95% CI: 1.9-9.4. Decreased mortality was associated with TB lymphadenitis (AOR: 0.24; 95% CI: 0.11-0.57. Conclusion (1 The registration of TB cases can be useful to understand the epidemiology of TB in local health facilities. (2 The defaulter and mortality rate of childhood TB is different to that of adult TB. (3 The rate of defaulting from treatment has declined over time.

  15. Pulmonary aspergilloma: A 15 years experience in Dar es Salaam ...

    African Journals Online (AJOL)

    There is a paucity of literature on the prevalence and surgical treatment of pulmonary aspergilloma in African countries. This was a retrospective review of cases managed at the Thoracic Surgical Unit of Muhimbili National Hospital, Dar es Salaam, Tanzania, over a 15-year period from June 1986 to May 2000. Ten patients ...

  16. Women and Educational Journalism: A Ten-year Perspective and Comparisons with Journals from Two Related Fields.

    Science.gov (United States)

    White, Arden

    Women's experiences on the editorial boards of and as authors for education journals are examined and compared with their experiences in counseling and development journals and psychology journals. In all cases, women are found to be underrepresented. After a productivity comparison between men and women, and an analysis of women's editorial board…

  17. Electronic medical record in cardiology: a 10-year Italian experience

    Directory of Open Access Journals (Sweden)

    Clara Carpeggiani

    2015-08-01

    Full Text Available SummaryObjectives:the aim of this study was to report a ten years experience in the electronic medical record (EMR use. An estimated 80% of healthcare transactions are still paper-based.Methods:an EMR system was built at the end of 1998 in an Italian tertiary care center to achieve total integration among different human and instrumental sources, eliminating paper-based medical records. Physicians and nurses who used EMR system reported their opinions. In particular the hospital activity supported electronically, regarding 4,911 adult patients hospitalized in the 2004- 2008 period, was examined.Results:the final EMR product integrated multimedia document (text, images, signals. EMR presented for the most part advantages and was well adopted by the personnel. Appropriateness evaluation was also possible for some procedures. Some disadvantages were encountered, such as start-up costs, long time required to learn how to use the tool, little to no standardization between systems and the EMR technology.Conclusion:the EMR is a strategic goal for clinical system integration to allow a better health care quality. The advantages of the EMR overcome the disadvantages, yielding a positive return on investment to health care organization.

  18. The present state and future prospects of occupational therapy using technical aids : From an analysis of Japanese Occupational Therapy Society journals for the last ten years.

    OpenAIRE

    笹田, 哲; 宮前, 珠子

    2014-01-01

    The present state of occupational therapy using technical aids was assessed by examining journals of the Japanese Occupational Therapy Society for the last ten years. The findings were that occupational therapists offered not only bathing aids and excretion aids, but also locomotion and communication aids. Technical aids manufactured by occupational therapists accounted for a little over 50% of the total number. Of the technical aids which the journals had deemed effective, in 70% of cases pl...

  19. Porous tantalum uncemented acetabular components in revision total hip arthroplasty: a minimum ten-year clinical, radiological and quality of life outcome study.

    Science.gov (United States)

    Konan, S; Duncan, C P; Masri, B A; Garbuz, D S

    2016-06-01

    Reconstruction of the acetabulum after failed total hip arthroplasty (THA) can be a surgical challenge in the presence of severe bone loss. We report the long-term survival of a porous tantalum revision acetabular component, its radiological appearance and quality of life outcomes. We reviewed the results of 46 patients who had undergone revision of a failed acetabular component with a Paprosky II or III bone defect and reconstruction with a hemispherical, tantalum acetabular component, supplementary screws and a cemented polyethylene liner. After a minimum follow-up of ten years (ten to 12), the survivorship of the porous tantalum acetabular component was 96%, with further revision of the acetabular component as the end point. The ten-year survivorship, with hip revision for any reason as the end point, was 92%. We noted excellent pain relief (mean Western Ontario and McMaster Universities Arthritis Index (WOMAC) score pain 92.6, (40 to 100)) and good functional outcomes (mean WOMAC function 90.3 (30.9 to 100), mean University of California Los Angeles activity scale 5 (2 to 10)) and generic quality of life measures (mean Short Form-12 (SF-12) physical component 48.3 (18.1 to 56.8), mean SF-12 mental component 56.7 (32.9 to 70.3)). Patient satisfaction with pain relief, function and return to recreational activities were excellent. Uncemented acetabular reconstruction using a tantalum acetabular component gives excellent clinical and quality of life outcomes at a minimum follow-up of ten years. Cite this article: Bone Joint J 2016;98-B:767-71. ©2016 The British Editorial Society of Bone & Joint Surgery.

  20. Long-term effects of a ten-year osteoporosis intervention program in a Swedish population—A cross-sectional study

    Directory of Open Access Journals (Sweden)

    Ann-Charlotte Grahn Kronhed

    2017-03-01

    Full Text Available The aim of the study was to explore long-term effects seven years after the completion of a ten-year community-based osteoporosis intervention program in Vadstena, Sweden. The association between calcaneal bone mineral density and several life style factors, and the impact of risk factors for sustaining a fracture after the age of 50 were also studied. Previous participants in the intervention group, and matched subjects were invited to calcaneal bone mass measurement by a portable device including the dual X-ray and laser (DXL technology by Calscan, and to complete a questionnaire in 2006. A total of 417 persons (63% of those invited in the intervention (I group, and 120 persons (47% of those invited in the control (C group participated. Mean age was 63 years (37–94 years. There was somewhat more knowledge of osteoporosis in the I-group (M = 18 than in the C-group (M = 17 (p −2.5. The long-term effects of a ten-year, community-based, osteoporosis intervention program on knowledge and behavior were modest seven years after its completion.

  1. Ten ways to design for disgust, sadness, and other enjoyments : A design approach to enrich product experiences with negative emotions

    NARCIS (Netherlands)

    Fokkinga, S.F.; Desmet, P.M.A.

    2013-01-01

    This paper demonstrates how designers can enrich user experiences by purposefully involving negative emotions in user-product interaction. This approach is derived from a framework of rich experience, which explains how and under what circumstances negative emotions make a product experience richer

  2. Prevalence of dental anxiety and fear among five to ten year old children: a behaviour based cross sectional study.

    Science.gov (United States)

    Chhabra, N; Chhabra, A; Walia, G

    2012-03-01

    Dental anxiety and fear pose a considerable challenge for the practice of clinical dentistry as these are problematic entities in the management of child patients and present a potential barrier to the utilization of oral health care services. The aim of this study was to estimate the prevalence of dental anxiety and fear among the 5-10 years aged Indian child population. A total of 523 children aged 5-10 years and their parents, visiting Krishna Dental College, Ghaziabad, India were finally recruited in this study. Dental Fear/anxiety distribution in the children was studied using the Indian parent's version of the Dental Subscale of the Children's Fear Survey Schedule (CFSS-DS). Total fear scores were calculated separately for boys and girls and at different age levels. The collected data was statistically analyzed using a SPSS statistical program. The estimated prevalence of dental anxiety among 5 to 10 year old children in the study population was 6.3%. The overall median CFSS-DS score was 23 and the overall mean value of CFSS-DS score was 24. The prevalence of dental anxiety in children aged 5 years was 7.9%, 7.1% for 6 years old, 6.6% in 7 years old, 6.5% in 8 years old, 6.3% for 9 year old children and 5.8% in children aged 10 years. No statistically significant gender differences were found in the dental anxiety scores. The most fear provoking situations were the sight of injections, the drilling procedures by the dentist, touch of a stranger and noise of drilling by the dentist. The results of this study indicate the need for preventive health education and intervention programmes in India to prevent and reduce dental anxiety/fear and to promote children's oral health.

  3. Temporal consistency between gross primary production and solar-induced chlorophyll fluorescence in the ten most populous megacity areas over years.

    Science.gov (United States)

    Cui, Yaoping; Xiao, Xiangming; Zhang, Yao; Dong, Jinwei; Qin, Yuanwei; Doughty, Russell B; Zhang, Geli; Wang, Jie; Wu, Xiaocui; Qin, Yaochen; Zhou, Shenghui; Joiner, Joanna; Moore, Berrien

    2017-11-02

    The gross primary production (GPP) of vegetation in urban areas plays an important role in the study of urban ecology. It is difficult however, to accurately estimate GPP in urban areas, mostly due to the complexity of impervious land surfaces, buildings, vegetation, and management. Recently, we used the Vegetation Photosynthesis Model (VPM), climate data, and satellite images to estimate the GPP of terrestrial ecosystems including urban areas. Here, we report VPM-based GPP (GPPvpm) estimates for the world's ten most populous megacities during 2000-2014. The seasonal dynamics of GPPvpm during 2007-2014 in the ten megacities track well that of the solar-induced chlorophyll fluorescence (SIF) data from GOME-2 at 0.5° × 0.5° resolution. Annual GPPvpm during 2000-2014 also shows substantial variation among the ten megacities, and year-to-year trends show increases, no change, and decreases. Urban expansion and vegetation collectively impact GPP variations in these megacities. The results of this study demonstrate the potential of a satellite-based vegetation photosynthesis model for diagnostic studies of GPP and the terrestrial carbon cycle in urban areas.

  4. Ten years on from the national service framework for long-term conditions: how far have we come?

    Science.gov (United States)

    Mendes, Aysha

    2015-03-01

    Aysha Mendes investigates whether the Department of Health's blueprint for improving care of long-term conditions in the UK has been successful amid the large-scale changes occurring in the NHS over recent years.

  5. [Ten-year incidence of fatal and non-fatal myocardial infarction in the elderly population of Madrid].

    Science.gov (United States)

    Novella, Blanca; Alonso, Margarita; Rodriguez-Salvanés, Francisco; Susi, Rosario; Reviriego, Blanca; Escalante, Luisa; Suárez, Carmen; Gabriel, Rafael

    2008-11-01

    To determine the incidence of and mortality due to myocardial infarction and coronary heart disease in the elderly population of Madrid, Spain. The study involved a population-based cohort of 1297 individuals aged over 64 years without cardiovascular disease who were recruited in 1995. All cases of fatal and non-fatal myocardial infarction recorded up until December 2004 were investigated and classified using WHO-MONICA (World Health Organization-Multinational MONItoring of trends and determinants in CArdiovascular disease) criteria. Men had a significantly higher cumulative incidence of ischemic events (P< .001) and sudden death (P< .001), and a non-significantly higher risk of myocardial infarction (6.30%; 95% confidence interval [CI], 4.33%-8.76%) than women (4.90%; 95% CI, 3.54%-6.70%; P=.181). While the risk of myocardial infarction increased with age (P< .05), gender differences tended to narrow. The incidence was higher in men (889/100 000 person-years) than women (610/100,000 person-years; P< .001) and increased with age (P< .01). This increase was progressive in women but not in men. The mortality rate was also higher in men (472/100,000 person-years; 95% CI, 248-697) than women (328/100,000 person-years; 95% CI, 188-469; P< .001), and was six times higher in the 385-year-old age group than in those aged 65-74 years (P< .001). The incidence of fatal and non-fatal myocardial infarction was very high in the elderly population of Madrid. Both incidence and mortality rates increased dramatically with age after 64 years. Rates were higher in men than women at all ages, though gender differences decreased with age.

  6. Ten-Year Summary and Evaluation of Operations and Performance of the Utica Aquifer and North Lake Basin Wetlands Restoration Project, 2004-2014

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, Lorraine M. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-11-01

    This document reviews the performance of the groundwater (and wetlands) restoration program implemented by the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) at the former CCC/USDA grain storage facility in Utica, Nebraska, during the first ten years of this initiative (2004-2014). The results of the program for the first five-year period of operation were previously discussed in detail (Argonne 2011). The present report focuses on treatment system operational data and regulatory compliance monitoring results for the site during the second five-year period of operation (2010-2014), together with the results of (1) ongoing monitoring and (2) targeted groundwater sampling for volatile organic compounds (VOCs) analyses conducted at Utica in 2015 (following completion of the tenth year of systems operation), to assess the 10-year progress of the Utica remediation effort.

  7. A review of the activities of the IAG working group on geomorphosites over the last ten years

    Science.gov (United States)

    Reynard, Emmanuel; Coratza, Paola

    2013-04-01

    During the last two decades a renewed interest emerged in the scientific community for geoheritage, geoconservation and geotourism research. This was the reason for the International Association of Geomorphologists (IAG) for creating a specific working group on geomorphosites in 2001, with the aim to improve knowledge and scientific research on the definition, assessment, cartography, promotion and conservation of geomorphological heritage. The working group is chaired by the two authors, experiences were shared during several workshops and international conferences, and results were collected in several special publications (http://www.geomorph.org/wg/wggs.html). Several intensive courses for Master and PhD students were also organized and a book was published, dedicated particularly to Master and PhD students working on geomorphosite issues (Reynard et al., 2009). This contribution proposes a review of the working group activities since 2001 that focused on four main domains: (1) Definition and conceptualization. Geomorphosites are a type of geosite that is portions of the geosphere that present a particular importance for the comprehension of the Earth's history. Geomorphosites have to be considered as the result of human valuation. Conceptualization related to the value of geomorphosites is still in course. Nevertheless, three groups of values can be demonstrated: the scientific value (that is the interest of sites for Earth history and for the history and epistemology of geomorphology), several additional values (aesthetic, ecological, and cultural in a broad sense), and use and management values, that can be divided in three groups (educational value, economic value, including the tourist value, and protection). The scientific and additional value can be considered as intrinsic values, whereas the management and use value are to be related to extrinsic or societal values. (2) Assessment. Several methods, based on the measurement of specific features of

  8. Ten years of the Tiger: Aedes albopictus presence in Australia since its discovery in the Torres Strait in 2005

    Directory of Open Access Journals (Sweden)

    Andrew F. van den Hurk

    2016-12-01

    Full Text Available The “Asian tiger mosquito”, Aedes albopictus, is highly invasive, an aggressive biter and a major arbovirus vector. It is not currently present on mainland Australia despite being intercepted on numerous occasions at international ports and infesting the Torres Strait of Australia since at least 2004. In the current paper, we describe the invasion and current status of Ae. albopictus in the Torres Strait, as well as research conducted to assess the threat of this species becoming established in arbovirus transmission cycles on the Australian mainland. Genetic analysis of the invading population demonstrated that the Indonesian region was the likely origin of the invasion and not Papua New Guinea (PNG as initially suspected. There was also intermixing between Torres Strait, PNG and Indonesian populations, indicating that the species could be re-introduced into the Torres Strait compromising any successful eradication programme. Vector competence experiments with endemic and exotic viruses revealed that Ae. albopictus from the Torres Strait are efficient alphavirus vectors, but less efficient flavivirus vectors. Ae. albopictus obtains blood meals from a range of vertebrate hosts (including humans, indicating that it could play a role in both zoonotic and human-mosquito arbovirus transmission cycles in Australia. Predictive models coupled with climate tolerance experiments suggest that a Torres Strait strain of Ae. albopictus could colonise southern Australia by overwintering in the egg stage before proliferating in the warmer months. Cohabitation experiments demonstrated that the presence of Aedes notoscriptus larvae in containers would not prevent the establishment of Ae. albopictus. Evidence from these studies, coupled with global experience suggests that we need to be prepared for the imminent invasion of Australia by Ae. albopictus by thoroughly understanding its biology and being willing to embrace emerging control technologies.

  9. Free Recall Episodic Memory Performance Predicts Dementia Ten Years prior to Clinical Diagnosis: Findings from the Betula Longitudinal Study

    Directory of Open Access Journals (Sweden)

    Carl-Johan Boraxbekk

    2015-05-01

    Full Text Available Background/Aims: Early dementia diagnosis is a considerable challenge. The present study examined the predictive value of cognitive performance for a future clinical diagnosis of late-onset Alzheimer's disease or vascular dementia in a random population sample. Methods: Cognitive performance was retrospectively compared between three groups of participants from the Betula longitudinal cohort. Group 1 developed dementia 11-22 years after baseline testing (n = 111 and group 2 after 1-10 years (n = 280; group 3 showed no deterioration towards dementia during the study period (n = 2,855. Multinomial logistic regression analysis was used to investigate the predictive value of tests reflecting episodic memory performance, semantic memory performance, visuospatial ability, and prospective memory performance. Results: Age- and education-corrected performance on two free recall episodic memory tests significantly predicted dementia 10 years prior to clinical diagnosis. Free recall performance also predicted dementia 11-22 years prior to diagnosis when controlling for education, but not when age was added to the model. Conclusion: The present results support the suggestion that two free recall-based tests of episodic memory function may be useful for detecting individuals at risk of developing dementia 10 years prior to clinical diagnosis.

  10. Free Recall Episodic Memory Performance Predicts Dementia Ten Years prior to Clinical Diagnosis: Findings from the Betula Longitudinal Study.

    Science.gov (United States)

    Boraxbekk, Carl-Johan; Lundquist, Anders; Nordin, Annelie; Nyberg, Lars; Nilsson, Lars-Göran; Adolfsson, Rolf

    2015-01-01

    Early dementia diagnosis is a considerable challenge. The present study examined the predictive value of cognitive performance for a future clinical diagnosis of late-onset Alzheimer's disease or vascular dementia in a random population sample. Cognitive performance was retrospectively compared between three groups of participants from the Betula longitudinal cohort. Group 1 developed dementia 11-22 years after baseline testing (n = 111) and group 2 after 1-10 years (n = 280); group 3 showed no deterioration towards dementia during the study period (n = 2,855). Multinomial logistic regression analysis was used to investigate the predictive value of tests reflecting episodic memory performance, semantic memory performance, visuospatial ability, and prospective memory performance. Age- and education-corrected performance on two free recall episodic memory tests significantly predicted dementia 10 years prior to clinical diagnosis. Free recall performance also predicted dementia 11-22 years prior to diagnosis when controlling for education, but not when age was added to the model. The present results support the suggestion that two free recall-based tests of episodic memory function may be useful for detecting individuals at risk of developing dementia 10 years prior to clinical diagnosis.

  11. Teaching Hospital, Kaduna: A 2-Year Experience

    African Journals Online (AJOL)

    Intraoperative Deaths 23. Lau G. Perioperative deaths in. Singapore: a forensic perspective in a study of 132 cases. Annals of. Academy of Medicine, Singapore. 1994; 23: 351-357. Beebe D S, Urban M, Belani К G. Anaesthetic management of bone marrow transplant recipients less than two years of age. Paeditr. Anaesth.

  12. Ten-year absolute fracture risk and hip bone strength in Canadian women with systemic lupus erythematosus.

    Science.gov (United States)

    Lee, Jennifer J Y; Aghdassi, Elaheh; Cheung, Angela M; Morrison, Stacey; Cymet, Anne; Peeva, Valentina; Neville, Carolyn; Hewitt, Sara; DaCosta, Deborah; Pineau, Christian; Pope, Janet; Fortin, Paul R

    2012-07-01

    Women with systemic lupus erythematosus (SLE) are at risk of osteoporosis (OP) and fractures because of SLE or its treatments. We aimed to determine in women with SLE (1) the prevalence of low bone mass (LBM) in those 50 years of age; (2) the 10-year absolute fracture risk in those > 40 years of age using the Canadian Fracture Risk Assessment Tool (FRAX); (3) bone quality using hip structural analysis (HSA); and (4) the associations between HSA and age, SLE duration, and corticosteroid exposure. Women without prior OP fractures were eligible. Bone mineral densities at the hip, spine, and femoral neck were determined using dual-energy x-ray absorptiometry. OP was determined using World Health Organization definitions for participants aged ≥ 50 years (32.8%), and LBM was defined as Z-scores ≤ -2.0 for those aged fracture (FRAX-Major) and hip fracture (FRAX-Hip) were calculated. FRAX-Major ≥ 20% or Hip ≥ 3% was considered high risk. HSA was done in a subgroup (n = 81) of patients. The study group was 271 women. Mean (SD) age was 43.8 (13.1) years and SLE duration was 11.6 (10.4) years. OP was diagnosed in 14.6% and LBM in 8.8%. FRAX-Major ≥ 20% was seen in 9 patients (5.3%), of whom 6 were taking OP medications. FRAX-Hip ≥ 3% occurred in 16 patients (9.4%), of whom 9 were taking OP medications. Buckling ratio at the left hip narrow neck was positively correlated with FRAX-Major, FRAX-Hip, SLE duration, and duration of corticosteroid use. LBM is prevalent in women with SLE who are fractures while HSA can assess bone structure noninvasively.

  13. Ten Years Of Subsidence Monitoring With SAR Interferometry And Its Contribution To Risk Management In Aguascalientes, Mexico

    Science.gov (United States)

    Esquivel, Ruben; Castaneda, Laura; Taud, Hind; Lira, Jorge

    2013-12-01

    A Study involving GPS and differential SAR interferometry (DInSAR) monitoring is developed to investigate a subsidence phenomenon in Aguascalientes valley and to obtain displacement models concerned with risk management applications and geodetic purposes. DInSAR study with archived Envisat data allows accumulated displacement mapping yearly, and recent TerraSAR-X data implementation provides a more accurate estimation of displacements, which is used for developing models to correct geodetic positions. The maximum subsidence rate calculated is 15 cm/year with a decreasing rate throughout time in some areas.

  14. Deaths from injury and poisoning of children in Liverpool: a ten-year survey 1978-1987.

    Science.gov (United States)

    Armstrong, A M; Robson, W J

    1992-05-01

    Deaths of children in Liverpool under 16 years of age from injury and poisoning were examined for the period 1978-1987: 174 deaths occurred during the 10-year period. The commonest causes of death were road traffic accidents: 103 cases (60%). Of these 87 were of pedestrians struck by vehicles. Many of these children were very young and were unsupervised, or poorly supervised by other children. Drivers of vehicles were largely responsible for the accidents in 20 cases. The ability of children to cope in various traffic situations is discussed and responsibilities of parents and drivers are considered in relation to matters of accident prevention.

  15. Incorporating gender perspective in small environmental projects. The experience of El Almanario in ten indigenous communities in Guatemala

    Directory of Open Access Journals (Sweden)

    BONI ARISTIZÁBAL, Alejandra

    2012-06-01

    Full Text Available The Almanario is a project management methodology created by Small Grants Programme in Guatemalawhich operates following United Nations Global Environment Fund premises. The main goal of ourresearch is to show the results of fourth compulsory gender measures included in the Almanario approachin ten indigenous communities in Western Guatemala. The research reveals women participation has beenincreased and had allowed them to manage project resources. Two measures (the Promotora role and mixedAdvisory Board are preliminary steps to visualize women leadership but more time is needed in orderto consolidate and increase women participation. Nursemaids are perceived by women as a good measureto increase participation and really appropriate in a patriarchal context. Gender and self-esteem trainingshave increased women self-esteem and awareness on women rights.

  16. Ten-Year Secular Trends in Youth Violence: Results from the Philadelphia Youth Risk Behavior Survey 2003-2013

    Science.gov (United States)

    Pool, Andrew C.; Patterson, Freda; Luna, Ingrid Y.; Hohl, Bernadette; Bauer, Katherine W.

    2017-01-01

    Background: Youth violence reduction is a public health priority, yet few studies have examined secular trends in violence among urban youth, who may be particularly vulnerable to numerous forms of violence. This study examines 10-year secular trends in the prevalence of violence-related behaviors among Philadelphia high school students. Methods:…

  17. Ten Years of "Latin-American Journal of Astronomy Education" RELEA: Achievements and Challenges for International Astronomy Education Development

    Science.gov (United States)

    Bretones, Paulo S.; Jafelice, Luiz C.; Horvath, Jorge E.

    2016-01-01

    This study reviews 10 years of "Latin-American Journal of Astronomy Education" (RELEA), showing that the journal has become a valuable resource for publishing and highlights its pathway as scholarly journal. Furthermore, it is also a call to astronomy education specialists to consolidate their efforts considering similar journals…

  18. Acacia saligna’s soil legacy effects persist up to ten years after clearing: Implications for ecological restoration

    Czech Academy of Sciences Publication Activity Database

    Nsikani, M. M.; Novoa, Ana; van Wilgen, B. W.; Keet, J.-H.; Gaertner, M.

    2017-01-01

    Roč. 42, č. 8 (2017), s. 880-889 ISSN 1442-9985 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : ecological impact * enzyme activities * invader control * restoration Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 1.708, year: 2016

  19. Ten years of percutaneous coronary intervention in a low-volume military treatment facility: a quality improvement project.

    Science.gov (United States)

    Fentanes, Emilio; Wisenbaugh, Thomas W

    2013-09-01

    The quality assurance of a percutaneous coronary intervention (PCI) program is particularly important when the volume of procedures is low in the center. Determine predictors of the 30-day and long-term incidence of stent thrombosis, myocardial infarction, and death from any cause for all PCIs performed at Tripler Army Medical Center from January 2002 to June 2012. 929 PCIs were performed in 795 patients, resulting in an average PCI volume of 88 per year. Follow-up data were obtained for 99.8% of the patients at 30 days and for 83% at 3 years. 18 deaths occurred during the first 30 days after PCI, with an observed morality rate of 2.26%. Multivariate logistic regression identified independent predictors of death at 30 days: stent thrombosis (OR 96), acute myocardial infarction, hemodynamic instability (OR 47), emergent (OR 17) or salvage (OR 28) PCI, and the need for preprocedural balloon pumping (OR 27). The long-term survival Kaplan-Meier estimates were 94% at 1 year and 90.4% at 3 years. The 30-day mortality was similar to the expected mortality based on the risk factors in the New York State Registry model, and long-term survival was comparable with that reported in large registries. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

  20. Ten-year trajectories of stressors and resources at work : Cumulative and chronic effects on health and well-being

    NARCIS (Netherlands)

    Igic, Ivana; Keller, Anita C.; Elfering, Achim; Tschan, Franziska; Kälin, Wolfgang; Semmer, Norbert K.

    2017-01-01

    Employing 5 waves of measurement over a period of 10 years, we explored the effects of exposure to constellations of conditions at work on physical and psychological strain, estimating the history of exposure over time. Specifically, we first tested if the 4 constellations postulated by the job