WorldWideScience

Sample records for teha seda mida

  1. Mida vähem, seda parem / Kaia Lehari

    Index Scriptorium Estoniae

    Lehari, Kaia, 1944-

    1998-01-01

    Funktsionalismist, teisenemistest aastail 1920-1960. Esindajaid : W. Gropius, L. Mies van der Rohe, Le Corbusier. Modernismist. Konstruktivismist (arhitektid vennad Vesninid, disainerid A. Rodtshenko, E. Lissitsky, V. Tatlin) ja ratsionaalse esteetika suunast (arhitektid N. A. Ladovski, K. Melnikov) Venemaal. Koolidest Bauhaus Saksamaal ja Vhutemas-Vhutein Venemaal. Bauhausi stiilist, mida pärast II Maailmasõda internatsionaalseks stiiliks nimetama hakati. Funktsionalismi näiteid Eestist: O. Siinmaa, E. Habermanni, H. Johansoni tööd

  2. Mida teha varemetega? / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2002-01-01

    1. ja 2. IV Tallinnas toimunud rahvusvahelise konverentsi "Varemed. Vahemerest Läänemereni" teisest konverentsipäevast, mis keskendus varemetele Tallinnas (Jaani seek, Rotermanni kvartal, Harju tänav, tselluloosikombinaat). Tiina-Mall Kreemi eestvedamisel Väliskunsti muuseumi korraldatud noortenäitusest "Elu varemete keskel"

  3. MIDAS

    International Nuclear Information System (INIS)

    Sjo, T.; Andersson, E.B.; Kornfeldt, H.

    1988-01-01

    The increasing importance of advanced and reliable in-service inspection of major reactor components has led to the development of a new tool for underwater inspections - MIDAS. This is a remotely operated vehicle carrying a TV camera and an eddy current probe, thus giving the inspector the freedom to easily maneuver into selected inspection areas. The combination of visual inspection with the possibility of EC evaluation of indications gives a high degree of confidence in the overall inspection results

  4. Improvisation Theatre Performance as Maintaining and Breaking Cultural Model Narratives. Artiklis uuritakse, kuidas improvisatsiooniteater ja seda žanri harrastavad trupid kannavad edasi teatud tüüpi kultuurilisi narratiive, mida samas mõjutavad reaalsed

    Directory of Open Access Journals (Sweden)

    Reetta Jokinen

    2012-04-01

    Full Text Available Artiklis uuritakse, kuidas improvisatsiooniteater ja seda žanri harrastavad trupid kannavad edasi teatud tüüpi kultuurilisi narratiive, mida samas mõjutavad reaalsed sündmused nii etenduse ruumis kui väljaspool seda. Lähemalt analüüsitakse üht Jyväskyläs tegutseva Improvisatsiooniteatri Joo etendust, selles loodud tegelasi ning nende kaudu esitatavaid kultuurilisi narratiive, milles segunevad erinevad sotsiaalsed, ajaloolised ja müütilised teemad. Kuigi improvisatsiooniteatri ajaloo, meetodite ja eesmärkide kohta on avaldatud palju praktilise kallakuga käsiraamatuid, on seda valdkonda siiski vähe uuritud. Mis tegelikult juhtub, kui inimesed improviseerivad? Teine küsimuste ring on seotud improviseeritud loo temaatika ja dünaamikaga. Improteatri etendus on koht, kus mängitakse simultaanselt läbi mitmeid erinevaid narratiive, kusjuures igal hetkel on iga süžee puhul õhus mitmeid erinevaid arenguvõimalusi, millest mõned on aktuaalsemad kui teised. Need narratiivid võivad ka üksteist kommenteerida või osutada teistele tekstidele, näiteks isegi mõnele nii triviaalsele asjale nagu varem aset leidnud vestlusele. Tekste interpreteeritakse alati suhtes ümbritseva kultuurilise kontekstiga, teiste tekstide ja diskursustega. Artiklis vaadeldakse, kuidas etendajate tehtud valikud kinnistavad või küsitlevad erinevaid kultuurispetsiifilisi stereotüüpseid narratiive, kuidas neid narratiive saaks uutest vaatepunktidest interpreteerida ning kuidas need peegeldavad suhteid trupis. Improetenduses toimuvat ei käsitleta juhuslike sündmustena, vaid kompleksse mõjutuste kogumina, kus etenduse kultuuriline ja esteetiline väljund sõltuvad paljus proovimeetodist, trupi dünaamikast, etendajate unikaalsetest isiklikest narratiividest ja tegeliku elu sündmustest ning laiemast kultuurikontekstist. Improetenduse puhul ei ole kuigi lihtne eristada ühe etendaja valikuid või etenduse pöördepunkte, sest kogu protsess põhineb t

  5. Mida teha naabri haukuva koeraga / Tõnis Kõiv

    Index Scriptorium Estoniae

    Kõiv, Tõnis, 1970-

    2008-01-01

    Naabri õiguste rikkumisest ning olmemüra tekitamisest. Ilmunud ka Põhjarannik 10. mai 2008, lk. 2 ; Meie Maa 12. mai 2008, lk. 2 ; Valgamaalane 13. mai 2008, lk. 2 ; Koit 15. mai 2008, lk. 6 ; Pärnu Postimees 16. mai 2008, lk. 15 ; Vali Uudised 16. mai 2008, lk. 2 ; Hiiu Leht 20. mai 2008, lk. 2 ; Virumaa Teataja 30. mai 2008, lk. 11 ; Lõunaleht 17. juuli 2008, lk. 2

  6. Telli seda - ei tea mida / Ike Volkov

    Index Scriptorium Estoniae

    Volkov, Ike, 1951-

    2011-01-01

    Olukorrast Tallinna linnaplaneerimises ja linnaehituses. Ametnike vastutusest, ametiasutuste kompetentsusest, töö efektiivsusest, kehtivate seadustega ja ettekirjutustega arvestamisest, probleemidest hangetega

  7. Mida teha "paadami ilaga"? : poliitiline kunst / Marco Laimre

    Index Scriptorium Estoniae

    Laimre, Marco, 1968-

    2006-01-01

    Näitus "Kapital (see veab meid alt)" Tallinna Kunstihoones kuni 19. II. Kuraator Simon Sheikh (NIFCA), osalejad loetletud. Oliver Ressleri, Fia-Stina Sandlundi, Maria Eichhorni (sünd. 1962) töödest, võrdlus eesti kunstisündmustega

  8. Mida teha järjepideva rahvastikuarengu nimel / Kalev Katus

    Index Scriptorium Estoniae

    Katus, Kalev, 1955-2008

    2007-01-01

    Rahvastikuteadlane annab ülevaate Eesti rahvastiku sündimustasemest kui rahvastikuprotsesse enim mõjutanud tegurist, analüüsib erinevate meetmete, sh rahakesksete meetmete mõju sündimusele ja pakub välja abinõud, mis aitavad tõsta sündimuse taastetasemele. Lisatud diagramm ja graafikud

  9. Mida usud, seda lõikad / Mart Raudsaar

    Index Scriptorium Estoniae

    Raudsaar, Mart, 1973-

    2003-01-01

    Autori sõnul on ka keskpäraste töötajatega erakordsete tulemuste saavutamine võimalik: tööandjal tuleb oma ootustest vihjete abil teada anda ning inimesed reageerivad neile oma käitumist vastavalt kohandades

  10. Teeksin kõike seda, mida teen / Viivi Eksta

    Index Scriptorium Estoniae

    Eksta, Viivi

    2000-01-01

    TÜ pedagoogika osakonna juhataja, Eesti Akadeemilise Pedagoogika Seltsi ja selle Tartu osakonna esinaine, Ühiskondliku Pedagoogika Uurimise Instituudi isiksuse arengu sektsiooni juhataja ja Perekasvatuse Instituudi eestvedaja dotsent Inger Kraav

  11. Osta seda, mida teised ei taha / Villu Zirnask

    Index Scriptorium Estoniae

    Zirnask, Villu, 1966-

    2005-01-01

    Investeerimisfondide analüüsiga tegelev firma Morningstar soovitab investoritel kasutada investeerimisstrateegiat, mis seisneb ebapopulaarsete investeerimisfondide osakute ostmises. Lisa: Kõige ebapopulaarsemad investeerimissektorid USA-s aastatel 1994-2004 (investeerimisfondide rahavoogude alusel)

  12. Tanel Toom: teen seda, mida armastan / intervjueerinud Kaarel Kressa

    Index Scriptorium Estoniae

    Toom, Tanel, 1982-

    2011-01-01

    Eesti režissöör Tanel Toom oma lühifilmist "Pihtimus", mis kandideeris parima lühifilmi kategoorias Oscarile, oma filmidest ja tulevikuplaanidest, lemmikutest tänavuste Oscari-nominentide hulgas, Oscarile kandideerimise tähtsusest

  13. Mida tohib ja mida ei tohi teha teadlane / Toivo Maimets ; intervjueerinud Raivo Juurak

    Index Scriptorium Estoniae

    Maimets, Toivo, 1957-

    2009-01-01

    Intervjuu Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituudi direktori, UNESCO rahvusvahelise bioeetika komitee aseesimehe professori Toivo Maimetsaga. Samas ka Oxfordi ülikooli professorist Richard Dawkinist

  14. MIDAS documentation

    International Nuclear Information System (INIS)

    Seeman, S.E.

    1981-09-01

    MIDAS, the Master Information and Data Acquisition System, is a computerized system being implemented on FFTF to control the work released to the plant. The purpose of this system is to demonstrate the safety enhancement provided for LMFBRs when the operator has instant recall to the status of all work released to the plant, the interrelationships between functional equipment groups in the plant, and the relationships of equipment to safety functions

  15. PyMidas: Interface from Python to Midas

    Science.gov (United States)

    Maisala, Sami; Oittinen, Tero

    2014-01-01

    PyMidas is an interface between Python and MIDAS, the major ESO legacy general purpose data processing system. PyMidas allows a user to exploit both the rich legacy of MIDAS software and the power of Python scripting in a unified interactive environment. PyMidas also allows the usage of other Python-based astronomical analysis systems such as PyRAF.

  16. Midas heeft gelijk.

    NARCIS (Netherlands)

    dr. Lars B. Borghouts

    2006-01-01

    Het boek "Lichamelijke Oefening" van Midas Dekkers heeft heel wat stof doen opwaaien de afgelopen maanden. Dit artikel is een uitgebreide analyse van het boek, en of de ophef die het heeft veroorzaakt terecht is.

  17. Mida teha tumeda minevikuga? / Bruno Groppo ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Groppo, Bruno

    2005-01-01

    Autor keskendub küsimusele, kuidas trauma üle elanud ühiskond peaks oma minevikust üle saama, kui tingimused riigis normaliseeruvad, ning käsitleb lähemalt sellega seonduvalt olukorda Argentinas, Tšiilis, Venemaal

  18. Mida teha, et lapsed koolist ei puuduks? / Triin Tomingas, Hille Hinsberg, Sirje Ess...[jt

    Index Scriptorium Estoniae

    2011-01-01

    Küsimusele vastavad lapsevanemad Triin Tomingas ja Hille Hinsberg, Saaremaa ühisgümnaasiumi algklasside õppealajuhataja Sirje Ess, Tallinna Pelgulinna gümnaasiumi direktor Tõnu Piibur, MTÜ Ellu psühholoog-koolitaja Tiia Lister

  19. Mida teha kutsekoolides, et lõpetajad oleksid sama edukad nagu Jamie Oliver? / Rita Siilivask

    Index Scriptorium Estoniae

    Siilivask, Rita

    2016-01-01

    Eesti, Sloveenia ja Poola kutsehariduse asjatundjate õppevisiidist Inglismaale, mis toimus programmi Erasmus+ kutsehariduse strateegilise partnerluse projektis „European Solutions in Quality Assurance - ESQA”

  20. Mida teha Lätiga? / Mari Kooskora ; kommenteerinud Marta Piigli, Endel Hango

    Index Scriptorium Estoniae

    Kooskora, Mari, 1969-

    2009-01-01

    Juhtimisülesanne, kus rahvusvahelises ettevõttes töötav regiooni direktor peab lahendama oma alluvuses olevas tütarettevõttes tekkinud vastuolud. Lahendust otsivad Vendor Eesti OÜ turundusjuht Marta Piigli ja SELF II koolitaja Endel Hango

  1. MiDAS

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Saunders, Aaron Marc; Albertsen, Mads

    2015-01-01

    The Microbial Database for Activated Sludge (MiDAS) field guide is a freely available online resource linking the identity of abundant and process critical microorganisms in activated sludge wastewater treatment systems to available data related to their functional importance. Phenotypic properties...... of some of these genera are described, but most are known only from sequence data. The MiDAS taxonomy is a manual curation of the SILVA taxonomy that proposes a name for all genus-level taxa observed to be abundant by large-scale 16 S rRNA gene amplicon sequencing of full-scale activated sludge...... communities. The taxonomy can be used to classify unknown sequences, and the online MiDAS field guide links the identity to the available information about their morphology, diversity, physiology and distribution. The use of a common taxonomy across the field will provide a solid foundation for the study...

  2. MIDAS Website. Revised

    Science.gov (United States)

    Goodman, Allen; Shively, R. Joy (Technical Monitor)

    1997-01-01

    MIDAS, Man-machine Integration Design and Analysis System, is a unique combination of software tools aimed at reducing design cycle time, supporting quantitative predictions of human-system effectiveness and improving the design of crew stations and their associated operating procedures. This project is supported jointly by the US Army and NASA.

  3. Titles of Midas

    Directory of Open Access Journals (Sweden)

    G. L. Huxley

    2001-09-01

    Full Text Available The Phrygian inscription on the tomb at Yazılıkaya (8th century gives Midas the titles wanax and lawagtas, paralled in Mycenaean, and there were strong connections between his dynasty and Greek Aeolis.

  4. Historia y leyendas de la seda China : la ruta de la seda

    Directory of Open Access Journals (Sweden)

    Esteban Llagostera Cuenca

    2008-01-01

    Full Text Available En la legendaria China, el cultivo del gusano de seda y la industria de la seda, así como las rutas comerciales con los países occidentales, se estableció desde el año 2460 a.C. hasta el siglo XIV, según una leyenda china. Su cultivo, fue uno de los secretos mejor guardados en la Historia (su divulgación se castigaba con la pena de muerte. La Ruta de la Seda, desde China hasta la costa de Siria, representó un gran itinerario comercial, así como un importante intercambio cultural.In legendary China, the grow of silkworm and the silk industry, as well as the trading route with western countries, was established from 2460 B.C. to XIV century, according to a Chinese legend. It was one of the best kept secrets in History (punished with death. The Silk Road from China to the coast of Syria, meant an important cultural exchange and a great commercial route.

  5. MiDAS

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca

    A deep understanding of the microbial communities and dynamics in wastewater treatment systems is a powerful tool for process optimization and design (Rittmann et al., 2006). With the advent of amplicon sequencing of the 16S rRNA gene, the diversity within the microbial communities can now...... web platform about the microbes in activated sludge and their associated ADs. The MiDAS taxonomy proposes putative names for each genus-level-taxon that can be used as a common vocabulary for all researchers in the field....

  6. The SEDA computer code and its utilization for Angra 1

    International Nuclear Information System (INIS)

    Fernandes Filho, T.L.

    1988-11-01

    The implementation of SEDA 2.0 computer code, developed at Ezeiza Atomic Center, Argentine for Angra 1 reactor is described. The SEDA code gives an estimate for radiological consequences of nuclear accidents with release of radiactive materials for the environment. This code is now available for an IBM PC-XT. The computer environment, the files used, data, the programining structure and the models used are presented. The input data and results for two sample case are described. (author) [pt

  7. The MIDAS Instrument Design and Characterization

    Science.gov (United States)

    Honniball, C. I.; Wright, R.; Lucey, P. G.

    2016-10-01

    The Miniaturized Infrared detector of Atmospheric Species (MIDAS) utilizes an uncooled microbolometer coupled with a Sagnac interferometer. MIDAS will be used to detect and quantify atmospheric constituents for a variety of science applications.

  8. 76 FR 13445 - Lycoming Valley Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority

    Science.gov (United States)

    2011-03-11

    ... Railroad Company-Operation Exemption--SEDA--COG Joint Rail Authority Lycoming Valley Railroad Company (LVRR... milepost 0.4 in Muncy, Lycoming County, Pa. The line is owned or leased by SEDA-COG Joint Rail Authority (SEDA-COG). LVRR states that the line it proposes to operate is an extension of its existing line of...

  9. 76 FR 13446 - Juniata Valley Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority

    Science.gov (United States)

    2011-03-11

    ... Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority Juniata Valley Railroad Company (JVRR... milepost 2.0 in Lewistown, Mifflin County, Pa. The line is owned or leased by SEDA-COG Joint Rail Authority (SEDA-COG). JVRR states that the line it proposes to operate is an extension of its existing line of...

  10. 76 FR 13445 - North Shore Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority

    Science.gov (United States)

    2011-03-11

    ... Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority North Shore Railroad Company (NSRR), a... milepost 2.0 in Berwick, Columbia County, Pa. The line is leased by SEDA-COG Joint Rail Authority (SEDA- COG). NSRR states that the line it proposes to operate is an extension of its existing line of...

  11. Mida teha, et kirikukäsiraamat meie kirikut ei lõhuks? / Thomas-Andreas Põder

    Index Scriptorium Estoniae

    Põder, Thomas-Andreas, 1976-

    2009-01-01

    Kirikukäsiraamatu esialgse redaktsiooni esitlus oli meie kirikuelus kahemõtteline sündmus: raamatu trükist ilmumine ja asjaosaliste tänamine oli rõõmustav, selle esitlemine lõpuleviidud tööna kurvastav

  12. MIDAS Has the Golden Touch!

    Science.gov (United States)

    Yamashita, Irene

    1995-01-01

    Several CD-ROM products are being developed in Hawaii as part of MIDAS (Multimedia Industry for the Development of Academic Software), which helps promote technology in the classroom. The article examines how technology provides opportunities for students to develop higher thinking and problem-solving skills. (SM)

  13. Mida ootab lapsevanem? / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2009-01-01

    Eesti koostöö kogu programmijuht Mati Salundi ja Tallinna Ülikooli sotsiaaltöö instituudi dotsent Anne Tiko viisid möödunud kevadel läbi uuringu, kus selgitasid, mida ootavad 1. klassi astuvate laste vanemad lasteaialt, koolilt, õpetajalt, kohalikult omavalitsuselt. Uuringu tulemusi kommenteerisid vestlusringis Mati Salundi, Lastevanemate Liidu koolitusjuht Kristiine Vahtramäe ja uuringu retsensent, Tallinna Ülikooli kasvatusteaduse instituudi professor Marika Veisson

  14. Õpingud välismaal - mida kaugemal, seda kallimad / Lana Stille, Agnes Absalon ; vahendaja Nelli Pello

    Index Scriptorium Estoniae

    Stille, Lana

    2006-01-01

    Õppemaksudest USA-s, Itaalias, Suurbritannias, Hollandis ja Soomes. Kommenteerivad Sean Patrick Williams Iowa Ülikoolist (USA), Thomas Mark Carey Leedsi Ülikoolist (Suurbritannia), Alies Hoitsma Windwshwimi Kristlikust Kõrgkoolist (Holland) ja Antti Tiainen Jyväskylä Ülikoolist (Soome)

  15. MIDAS [Master Information and Data Acquisition System

    International Nuclear Information System (INIS)

    Ball, D.L.

    1986-01-01

    The Master Information and Data Acquisition System (MIDAS) is a computerized work control system that provides 24-hour, real-time access to plant equipment information and work package status. It is used in the 400 Area of the Department of Energy (DOE) Hanford Site in Richland, Washington. MIDAS was originally created to aid in the release and control of work at the Fast Flux Test Facility (FFTF), which is operated by the Westinghouse Hanford Company for the DOE. After MIDAS performed that function at FFTF successfully for over two years, its role was expanded to provide similar functions for other facilities supporting the LMR mission. Through its ability to provide online, accurate information on plant components, safety criteria, and work package status, MIDAS reinforces Operations functions and the control and authorization of maintenance activities in the FFTF plant and in other related facilities. Thus, MIDAS enhances the operational safety, as well as the planning and scheduling process for these facilities. MIDAS consists of three parts: The Plant Tracking System (PTS), the Work Control Log (WCL), and the MIDAS Component Indices

  16. 76 FR 13446 - Nittany Bald and Eagle Railroad Company-Operation Exemption-SEDA-COG Joint Rail Authority

    Science.gov (United States)

    2011-03-11

    ... Eagle Railroad Company-Operation Exemption-SEDA- COG Joint Rail Authority Nittany Bald and Eagle... 0.0 and milepost 1.8 in Castanea, Clinton County, Pa. The line is owned or leased by SEDA-COG Joint Rail Authority (SEDA-COG). N&BE states that the line it proposes to operate is an extension of its...

  17. MODELING HUMAN RELIABILITY ANALYSIS USING MIDAS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Donald D. Dudenhoeffer; Bruce P. Hallbert; Brian F. Gore

    2006-05-01

    This paper summarizes an emerging collaboration between Idaho National Laboratory and NASA Ames Research Center regarding the utilization of high-fidelity MIDAS simulations for modeling control room crew performance at nuclear power plants. The key envisioned uses for MIDAS-based control room simulations are: (i) the estimation of human error with novel control room equipment and configurations, (ii) the investigative determination of risk significance in recreating past event scenarios involving control room operating crews, and (iii) the certification of novel staffing levels in control rooms. It is proposed that MIDAS serves as a key component for the effective modeling of risk in next generation control rooms.

  18. H-Seda: Partial Packet Recovery with Heterogeneous Block Sizes for Wireless Sensor Networks

    KAUST Repository

    Meer, Ammar M.

    2012-12-08

    Wireless sensor networks (WSN) have been largely used in various applications due to its ease of deployment and scalability. The throughput of such networks, however, suffers from high bit error rates mainly because of medium characteristics. Maximizing bandwidth utilization while maintaining low frame error rate has been an interesting problem. Frame fragmentation into small blocks with dedicated error detection codes per block can reduce the unnecessary retransmission of the correctly received blocks. The optimal block size, however, varies based on the wireless channel conditions. In addition, blocks within a frame can have different optimal sizes based on the variations on interference patterns. This thesis studies two dynamic partial packet recovery approaches experimentally over several interference intensities with various transmission-power levels. It also proposes a dynamic data link layer protocol: Hybrid Seda (H-Seda). H-Seda effectively addresses the challenges associated with dynamic partitioning of blocks while taking the observed error patterns into consideration. The design of H-Seda is discussed in details and compared to other previous approaches, namely Seda+ and Seda. The implementation of H-Seda shows substantial enhancements over fixed-size partial packet recovery protocols, achieving up to 2.5x improvement in throughput when the channel condition is noisy, while delay experienced decreases to only 14 % of the delay observed in Seda. On average, it shows 35% gain in goodput across all channel conditions used in our experiments. This significant improvement is due to the selective nature of H-Seda which minimizes retransmission overhead by selecting the appropriate number of blocks in each data frame. Additionally, H-Seda successfully reduces block overhead by 50% through removing block number field reaching to better performance when channel conditions are identical.

  19. SEDA: A software package for the Statistical Earthquake Data Analysis

    Science.gov (United States)

    Lombardi, A. M.

    2017-03-01

    In this paper, the first version of the software SEDA (SEDAv1.0), designed to help seismologists statistically analyze earthquake data, is presented. The package consists of a user-friendly Matlab-based interface, which allows the user to easily interact with the application, and a computational core of Fortran codes, to guarantee the maximum speed. The primary factor driving the development of SEDA is to guarantee the research reproducibility, which is a growing movement among scientists and highly recommended by the most important scientific journals. SEDAv1.0 is mainly devoted to produce accurate and fast outputs. Less care has been taken for the graphic appeal, which will be improved in the future. The main part of SEDAv1.0 is devoted to the ETAS modeling. SEDAv1.0 contains a set of consistent tools on ETAS, allowing the estimation of parameters, the testing of model on data, the simulation of catalogs, the identification of sequences and forecasts calculation. The peculiarities of routines inside SEDAv1.0 are discussed in this paper. More specific details on the software are presented in the manual accompanying the program package.

  20. Superconductivity in Spain. Midas program

    International Nuclear Information System (INIS)

    Yndurain, F.

    1996-01-01

    The different activities in the field of applied superconductivity carried out in Spain under the auspices of the MIDAS program are reported. Applications using both low- and high-temperature superconductors are considered. In the low temperature superconductors case, the design and construction of a 1 mega joule SMES (Superconducting Magnetic Energy Storage) unit, as well as the fabrication of voltage and resistance standards, are reviewed. Developments involving the design and fabrication of an inductive current fault limited and mono- and multi-filamentary wires and tapes using high-temperature superconductors are discussed. Finally, the prospects for the application of superconductivity technology to electric power systems for the electric utilities is considered. (author)

  1. "Beverly Hills 90210" : kes mida teeb / Tiina Lepiste

    Index Scriptorium Estoniae

    Lepiste, Tiina

    2003-01-01

    Aaron Spellingu produtseeritud ja 2000. aastal lõpetatud menuseriaalis "Beverly Hills 90210" osalenud näitlejate edaspidisest elust seoses plaaniga teha täispikk mängufilm "10 Year High School Reunion"

  2. Microwave detection of air showers with MIDAS

    Energy Technology Data Exchange (ETDEWEB)

    Facal San Luis, P., E-mail: facal@kicp.uchicago.edu [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Alekotte, I. [Centro Atomico Bariloche and Instituto Balseiro (CNEA-UNCuyo-CONICET), 8400 San Carlos de Bariloche, Rio Negro (Argentina); Alvarez, J. [Universidad de Santiago de Compostela, Departamento de Fisica de Particulas, Campus Sur, E-15782 Santiago de Compostela (Spain); Berlin, A. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Bertou, X. [Centro Atomico Bariloche and Instituto Balseiro (CNEA-UNCuyo-CONICET), 8400 San Carlos de Bariloche, Rio Negro (Argentina); Bogdan, M.; Bohacova, M. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Bonifazi, C. [Univ. Federal do Rio de Janeiro (UFRJ), Instituto de Fisica, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Carvalho, W.R. [Universidad de Santiago de Compostela, Departamento de Fisica de Particulas, Campus Sur, E-15782 Santiago de Compostela (Spain); Mello Neto, J.R.T. de [Univ. Federal do Rio de Janeiro (UFRJ), Instituto de Fisica, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; Rouille d& #x27; Orfeuil, B. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); and others

    2012-01-11

    MIDAS (MIcrowave Detector of Air Showers) is a prototype of a microwave telescope to detect extensive air showers: it images a 20{sup Degree-Sign } Multiplication-Sign 10{sup Degree-Sign} region of the sky with a 4.5 m parabolic reflector and 53 feeds in the focal plane. It has been commissioned in March 2010 and is currently taking data. We present the design, performance and first results of MIDAS.

  3. Microwave detection of air showers with MIDAS

    International Nuclear Information System (INIS)

    Facal San Luis, P.; Alekotte, I.; Alvarez, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; Rouille d’Orfeuil, B.

    2012-01-01

    MIDAS (MIcrowave Detector of Air Showers) is a prototype of a microwave telescope to detect extensive air showers: it images a 20 ° ×10 ° region of the sky with a 4.5 m parabolic reflector and 53 feeds in the focal plane. It has been commissioned in March 2010 and is currently taking data. We present the design, performance and first results of MIDAS.

  4. Measures of uncertainty, importance and sensitivity of the SEDA code

    International Nuclear Information System (INIS)

    Baron, J.; Caruso, A.; Vinate, H.

    1996-01-01

    The purpose of this work is the estimation of the uncertainty on the results of the SEDA code (Sistema de Evaluacion de Dosis en Accidentes) in accordance with the input data and its parameters. The SEDA code has been developed by the Comision Nacional de Energia Atomica for the estimation of doses during emergencies in the vicinity of Atucha and Embalse, nuclear power plants. The user should feed the code with meteorological data, source terms and accident data (timing involved, release height, thermal content of the release, etc.) It is designed to be used during the emergency, and to bring fast results that enable to make decisions. The uncertainty in the results of the SEDA code is quantified in the present paper. This uncertainty is associated both with the data the user inputs to the code, and with the uncertain parameters of the code own models. The used method consisted in the statistical characterization of the parameters and variables, assigning them adequate probability distributions. These distributions have been sampled with the Latin Hypercube Sampling method, which is a stratified multi-variable Monte-Carlo technique. The code has been performed for each of the samples and finally, a result sample has been obtained. These results have been characterized from the statistical point of view (obtaining their mean, most probable value, distribution shape, etc.) for several distances from the source. Finally, the Partial Correlation Coefficients and Standard Regression Coefficients techniques have been used to obtain the relative importance of each input variable, and the Sensitivity of the code to its variations. The measures of Importance and Sensitivity have been obtained for several distances from the source and various cases of atmospheric stability, making comparisons possible. This paper allowed to confide in the results of the code, and the association of their uncertainty to them, as a way to know the limits in which the results can vary in a real

  5. The MIDAS Touch: Mixed Data Sampling Regression Models

    OpenAIRE

    Ghysels, Eric; Santa-Clara, Pedro; Valkanov, Rossen

    2004-01-01

    We introduce Mixed Data Sampling (henceforth MIDAS) regression models. The regressions involve time series data sampled at different frequencies. Technically speaking MIDAS models specify conditional expectations as a distributed lag of regressors recorded at some higher sampling frequencies. We examine the asymptotic properties of MIDAS regression estimation and compare it with traditional distributed lag models. MIDAS regressions have wide applicability in macroeconomics and �nance.

  6. MWIR hyperspectral imaging with the MIDAS instrument

    Science.gov (United States)

    Honniball, Casey I.; Wright, Rob; Lucey, Paul G.

    2017-02-01

    Hyperspectral imaging (HSI) in the Mid-Wave InfraRed (MWIR, 3-5 microns) can provide information on a variety of science applications from determining the chemical composition of lava lakes on Jupiter's moon Io, to investigating the amount of carbon liberated into the Earth's atmosphere during a wildfire. The limited signal available in the MWIR presents technical challenges to achieving high signal-to-noise ratios, and therefore it is typically necessary to cryogenically cool MWIR instruments. With recent improvements in microbolometer technology and emerging interferometric techniques, we have shown that uncooled microbolometers coupled with a Sagnac interferometer can achieve high signal-to-noise ratios for long-wave infrared HSI. To explore if this technique can be applied to the MWIR, this project, with funding from NASA, has built the Miniaturized Infrared Detector of Atmospheric Species (MIDAS). Standard characterization tests are used to compare MIDAS against a cryogenically cooled photon detector to evaluate the MIDAS instruments' ability to quantify gas concentrations. Atmospheric radiative transfer codes are in development to explore the limitations of MIDAS and identify the range of science objectives that MIDAS will most likely excel at. We will simulate science applications with gas cells filled with varying gas concentrations and varying source temperatures to verify our results from lab characterization and our atmospheric modeling code.

  7. A restructuring proposal for MIDAS

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2000-01-01

    In order to develop a template for the MIDAS computer code, current data saving and transferring methods used in MELCOR are addressed first, and then a restructured module for the SPR package has been developed to be applied to MELCOR. The current MELCOR code ensures a fixed-size storage for four different data types, and manages the input-dependent data size by storing the data on the stacked packages. It uses pointer to identify the variables between the packages. This technique causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90, however, make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to a restructured module development for the SPR package. An efficient memory treatment and an easy understanding of the code are the benefit from this developed module. The validation of the template has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. The template for the SPR package hints the extension of the template to the entire code. It is expected that the template will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  8. MIDAS - ESO's new image processing system

    Science.gov (United States)

    Banse, K.; Crane, P.; Grosbol, P.; Middleburg, F.; Ounnas, C.; Ponz, D.; Waldthausen, H.

    1983-03-01

    The Munich Image Data Analysis System (MIDAS) is an image processing system whose heart is a pair of VAX 11/780 computers linked together via DECnet. One of these computers, VAX-A, is equipped with 3.5 Mbytes of memory, 1.2 Gbytes of disk storage, and two tape drives with 800/1600 bpi density. The other computer, VAX-B, has 4.0 Mbytes of memory, 688 Mbytes of disk storage, and one tape drive with 1600/6250 bpi density. MIDAS is a command-driven system geared toward the interactive user. The type and number of parameters in a command depends on the unique parameter invoked. MIDAS is a highly modular system that provides building blocks for the undertaking of more sophisticated applications. Presently, 175 commands are available. These include the modification of the color-lookup table interactively, to enhance various image features, and the interactive extraction of subimages.

  9. MIDAS: an effective tool for work management

    International Nuclear Information System (INIS)

    Ball, D.L.; Billings, M.P.; McCargar, S.B.; Talbot, M.D.; Topping, C.F.

    1985-01-01

    The computerized Master Information Data Acquisition System (MIDAS) is used to control work at facilities that support the Liquid Metal Reactor (LMR) program on the Hanford Site at Richland, Washington. Functions of this software system are to: track authorized maintenance activities, enhance operational safety, track schedule, manpower, and material constraints during work preparation, provide a management tool for quality measurement techniques, and provide an overall repository for technical and safety-related information on components at the Hanford Site 400 Area facilities. This paper describes MIDAS and how it is used as a work management tool. 1 fig

  10. A New Python Library for Spectroscopic Analysis with MIDAS Style

    Science.gov (United States)

    Song, Y.; Luo, A.; Zhao, Y.

    2013-10-01

    The ESO MIDAS is a system for astronomers to analyze data which many astronomers are using. Python is a high level script language and there are many applications for astronomical data process. We are releasing a new Python library which realizes some MIDAS commands in Python. People can use it to write a MIDAS style Python code. We call it PydasLib. It is a Python library based on ESO MIDAS functions, which is easily used by astronomers who are familiar with the usage of MIDAS.

  11. Suppurative peritonitis by Klebsiella pneumoniae in captive gold-handed tamarin (Saguinus midas midas).

    Science.gov (United States)

    Guerra, Maria F L; Teixeira, Rodrigo H F; Ribeiro, Vanessa L; Cunha, Marcos P V; Oliveira, Maria G X; Davies, Yamê M; Silva, Ketrin C; Silva, Ana P S; Lincopan, Nilton; Moreno, Andrea M; Knöbl, Terezinha

    2016-02-01

    This report describes an outbreak of suppurative peritonitis caused by Klebsiella pneumoniae in an adult female of captive golden-handed tamarin (Saguinus midas midas). Two virulent and multidrug-resistant strains were isolated and classified through MLST as ST60 and ST1263. The microbiological diagnosis works as a support tool for preventive measures. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Cointegrating MiDaS Regressions and a MiDaS Test

    OpenAIRE

    J. Isaac Miller

    2011-01-01

    This paper introduces cointegrating mixed data sampling (CoMiDaS) regressions, generalizing nonlinear MiDaS regressions in the extant literature. Under a linear mixed-frequency data-generating process, MiDaS regressions provide a parsimoniously parameterized nonlinear alternative when the linear forecasting model is over-parameterized and may be infeasible. In spite of potential correlation of the error term both serially and with the regressors, I find that nonlinear least squares consistent...

  13. Poliitikud tõrjuvad väiteid, et Euroopa Liit tahab Eestist kakskeelset riiki teha / Kristjan Roos

    Index Scriptorium Estoniae

    Roos, Kristjan, 1978-

    2005-01-01

    USA geopoliitilise alalüüsi keskuse Axis Information and Analysis Euroopas tegutseva analüütiku Simon Araloffi sõnul tahab EL Eestist kakskeelset riiki teha. Eesti poliitikud selle väitega ei nõustu

  14. Modeling human reliability analysis using MIDAS

    International Nuclear Information System (INIS)

    Boring, R. L.

    2006-01-01

    This paper documents current efforts to infuse human reliability analysis (HRA) into human performance simulation. The Idaho National Laboratory is teamed with NASA Ames Research Center to bridge the SPAR-H HRA method with NASA's Man-machine Integration Design and Analysis System (MIDAS) for use in simulating and modeling the human contribution to risk in nuclear power plant control room operations. It is anticipated that the union of MIDAS and SPAR-H will pave the path for cost-effective, timely, and valid simulated control room operators for studying current and next generation control room configurations. This paper highlights considerations for creating the dynamic HRA framework necessary for simulation, including event dependency and granularity. This paper also highlights how the SPAR-H performance shaping factors can be modeled in MIDAS across static, dynamic, and initiator conditions common to control room scenarios. This paper concludes with a discussion of the relationship of the workload factors currently in MIDAS and the performance shaping factors in SPAR-H. (authors)

  15. Yet another look at MIDAS regression

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans)

    2016-01-01

    textabstractA MIDAS regression involves a dependent variable observed at a low frequency and independent variables observed at a higher frequency. This paper relates a true high frequency data generating process, where also the dependent variable is observed (hypothetically) at the high frequency,

  16. Microwave detection of air showers with MIDAS

    Czech Academy of Sciences Publication Activity Database

    Facal San Luis, P.; Alekotte, I.; Alvarez, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Boháčová, Martina; Bonifazi, C.; Carvalho, W.R.; de Mello Neto, J.R.T.; Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; d´Orfeuil, B.R.; Santos, E.M.; Wayne, S.; Williams, C.; Zas, E.

    2012-01-01

    Roč. 662, Sup. 1 (2012), "S118"-"S123" ISSN 0168-9002 R&D Projects: GA MŠk(CZ) LA08016 Institutional research plan: CEZ:AV0Z10100502 Keywords : MIDAS (Microwave Detector of Air Showers) * extensive air showers Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.142, year: 2012

  17. 1) Mis teile praeguses eesti kirjanduses ei meeldi? 2) Mida tuleks teha, et asi läheks nii, nagu teile meeldib? : [küsitlus

    Index Scriptorium Estoniae

    2002-01-01

    Vastavad : Vaapo Vaher, Elo Lindsalu, Olev Remsu, Jüri Ehlvest, François Serpent, Sven Kivisildnik, Linnar Priimägi, Aino Pervik, Mati Unt, Contra, Fagira D. Morti, Aapo Ilves, Aarne Ruben, Juku-Kalle Raid

  18. Molecular Isotopic Distribution Analysis (MIDAs) with adjustable mass accuracy.

    Science.gov (United States)

    Alves, Gelio; Ogurtsov, Aleksey Y; Yu, Yi-Kuo

    2014-01-01

    In this paper, we present Molecular Isotopic Distribution Analysis (MIDAs), a new software tool designed to compute molecular isotopic distributions with adjustable accuracies. MIDAs offers two algorithms, one polynomial-based and one Fourier-transform-based, both of which compute molecular isotopic distributions accurately and efficiently. The polynomial-based algorithm contains few novel aspects, whereas the Fourier-transform-based algorithm consists mainly of improvements to other existing Fourier-transform-based algorithms. We have benchmarked the performance of the two algorithms implemented in MIDAs with that of eight software packages (BRAIN, Emass, Mercury, Mercury5, NeutronCluster, Qmass, JFC, IC) using a consensus set of benchmark molecules. Under the proposed evaluation criteria, MIDAs's algorithms, JFC, and Emass compute with comparable accuracy the coarse-grained (low-resolution) isotopic distributions and are more accurate than the other software packages. For fine-grained isotopic distributions, we compared IC, MIDAs's polynomial algorithm, and MIDAs's Fourier transform algorithm. Among the three, IC and MIDAs's polynomial algorithm compute isotopic distributions that better resemble their corresponding exact fine-grained (high-resolution) isotopic distributions. MIDAs can be accessed freely through a user-friendly web-interface at http://www.ncbi.nlm.nih.gov/CBBresearch/Yu/midas/index.html.

  19. MIDAS: Regionally linear multivariate discriminative statistical mapping.

    Science.gov (United States)

    Varol, Erdem; Sotiras, Aristeidis; Davatzikos, Christos

    2018-07-01

    Statistical parametric maps formed via voxel-wise mass-univariate tests, such as the general linear model, are commonly used to test hypotheses about regionally specific effects in neuroimaging cross-sectional studies where each subject is represented by a single image. Despite being informative, these techniques remain limited as they ignore multivariate relationships in the data. Most importantly, the commonly employed local Gaussian smoothing, which is important for accounting for registration errors and making the data follow Gaussian distributions, is usually chosen in an ad hoc fashion. Thus, it is often suboptimal for the task of detecting group differences and correlations with non-imaging variables. Information mapping techniques, such as searchlight, which use pattern classifiers to exploit multivariate information and obtain more powerful statistical maps, have become increasingly popular in recent years. However, existing methods may lead to important interpretation errors in practice (i.e., misidentifying a cluster as informative, or failing to detect truly informative voxels), while often being computationally expensive. To address these issues, we introduce a novel efficient multivariate statistical framework for cross-sectional studies, termed MIDAS, seeking highly sensitive and specific voxel-wise brain maps, while leveraging the power of regional discriminant analysis. In MIDAS, locally linear discriminative learning is applied to estimate the pattern that best discriminates between two groups, or predicts a variable of interest. This pattern is equivalent to local filtering by an optimal kernel whose coefficients are the weights of the linear discriminant. By composing information from all neighborhoods that contain a given voxel, MIDAS produces a statistic that collectively reflects the contribution of the voxel to the regional classifiers as well as the discriminative power of the classifiers. Critically, MIDAS efficiently assesses the

  20. Assessing the ecosystem effects of the abalone Haliotis midae from ...

    African Journals Online (AJOL)

    Assessing the ecosystem effects of the abalone Haliotis midae from its diet and foraging ... midae is commercially exploited and seriously threatened by overfishing. ... of the ecosystem because of associated changes in community structure. ... of this previously abundant herbivore on the south-west coast of South Africa, we ...

  1. Catherine Austin Fitts: kõike ei tohi teha kasumi nimel / Catherine Austin Fitts ; intervjueerinud Külli-Riin Tigasson

    Index Scriptorium Estoniae

    Austin Fitts, Catherine

    2009-01-01

    Firma Solari Inc juht peab praegu toimuvas süüdlaseks seda, et pangad ja valitsused vaatasid ohtudest mööda; lasti kasvada kinnisvaramullil. Ta kutsuks inimesi üles omavahelisele raharinglusele, jättes kulukad vahendajad kõrvale

  2. Shaping the manufacturing industry performance: MIDAS approach

    International Nuclear Information System (INIS)

    Turhan, Ibrahim M.; Sensoy, Ahmet; Hacihasanoglu, Erk

    2015-01-01

    We aim to find out whether the exchange rate (against US dollar) or the interest rate (in local currency) is a better variable in predicting the capacity utilization rate of manufacturing industry (CUR) of Turkey after the 2008 global financial crisis. In that manner, we implement dynamic mixed data sampling (MIDAS) regression model to forecast monthly changes in CUR by using daily changes in the exchange rate and the interest rate separately. The results show that exchange rate has a better forecast performance suggesting that it is a stronger determinant in shaping the manufacturing industry

  3. MIDAS/PK code development using point kinetics model

    International Nuclear Information System (INIS)

    Song, Y. M.; Park, S. H.

    1999-01-01

    In this study, a MIDAS/PK code has been developed for analyzing the ATWS (Anticipated Transients Without Scram) which can be one of severe accident initiating events. The MIDAS is an integrated computer code based on the MELCOR code to develop a severe accident risk reduction strategy by Korea Atomic Energy Research Institute. In the mean time, the Chexal-Layman correlation in the current MELCOR, which was developed under a BWR condition, is appeared to be inappropriate for a PWR. So as to provide ATWS analysis capability to the MIDAS code, a point kinetics module, PKINETIC, has first been developed as a stand-alone code whose reference model was selected from the current accident analysis codes. In the next step, the MIDAS/PK code has been developed via coupling PKINETIC with the MIDAS code by inter-connecting several thermal hydraulic parameters between the two codes. Since the major concern in the ATWS analysis is the primary peak pressure during the early few minutes into the accident, the peak pressure from the PKINETIC module and the MIDAS/PK are compared with the RETRAN calculations showing a good agreement between them. The MIDAS/PK code is considered to be valuable for analyzing the plant response during ATWS deterministically, especially for the early domestic Westinghouse plants which rely on the operator procedure instead of an AMSAC (ATWS Mitigating System Actuation Circuitry) against ATWS. This capability of ATWS analysis is also important from the view point of accident management and mitigation

  4. O PAPEL DA ÁFRICA NA NOVA ROTA DA SEDA MARÍTIMA

    Directory of Open Access Journals (Sweden)

    Diego Pautasso

    2017-01-01

    Full Text Available O objetivo do presente artigo é analisar o lugar da África na construção da Nova Rota da Seda Marítima. Este é justamente um dos vetores do ambicioso projeto chinês de integração da Ásia, Europa e África, lançada em 2013 sob título de Iniciativa OBOR (One Belt, One Road. Na medida que os desafios da reconstrução nacional são superados, a China torna-se mais assertiva e dá forma à sua estratégia de inserção mundial. Nesse sentido, a Nova Rota da Seda agrega os objetivos centrais da diplomacia da China para o século XXI, reservando à África a condição de trampolim para que o projeto se torne global.

  5. Entramados de la seda en México durante el siglo XIX y principios del XX

    OpenAIRE

    García Corzo, Rebeca Vanesa

    2016-01-01

    El objetivo de la investigación es realizar un panorama general del desarrollo de la industria de la seda en México durante el siglo XIX y principios del XX desde una perspectiva CTS a través de la secuencia de proyectos efímeros que constituyó el proceso. La hipótesis defendida es que aunque los grandes proyectos fueron efímeros la iniciativa para la puesta en práctica de la industria de la seda no fue abandonada porque se consiguió mantener el apoyo de la sociedad de la época. Esto se logró...

  6. The Steady State Calculation for SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2010-01-01

    KAERI is developing a new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. Before the severe accident sequences are estimated, it is prerequisite that MIDAS code predicts the steady state conditions properly. But MIDAS code does not include the heat transfer model for the helical tube. Therefore, the heat transfer models for the helical tube from TASS/SMR-S were implemented into MIDAS code. To estimate the validity of the implemented heat transfer correlations for the helical tube and the input data, the steady state was recalculated with MIDAS/SMR based on design level 2 and compared with the design values

  7. Maa, mis on ja mida ei ole / Õnne Kepp

    Index Scriptorium Estoniae

    Kepp, Õnne

    2006-01-01

    Gustav Suitsu 1913. aastal ilmunud luulekogust "Tuulemaa". Tuulemaa kujundit kasutatakse Eestimaa sünonüümina, ühtaegu nii reaalse maana kui ka irreaalse paigana, mida ei eksisteeri, mida pole olemas

  8. Development of GUI systems for the MIDAS code

    International Nuclear Information System (INIS)

    Kim, K.R.; Park, S.H.; Kim, D.H.

    2004-01-01

    MIDAS is being developed at KAERI based on MELCOR as an integrated severe accident analysis code with existing model modification and new model addition. MIDAS was restructured to avoid the pointer based variable referencing style of MELCOR, and enhanced the memory effectiveness using the dynamic allocation method of Fortran 90. This paper describes recent activities of developing the GUI environments for MIDAS code at KAERI. Up to now, we have developed the four PC-based subsystems, which are IEDIT, IPLOT, SATS and HyperKAMG. IEDIT is an input management system that can read MELCOR input files and display its information in the Window panels. Users can modify each item in the panel and the input file will be modified according to that changes. IPLOT is a simple plotting system that can draw MIDAS plot variables trend graphs. SATS is developed as a severe accident training simulator that can display nuclear plant behavior graphically. Moreover SATS provides several controllable pumps and valves which appeared in the severe accidence. Together with SATS and the online severe accident guidance HyperKAMG, combined properly, severe accident mitigation scenarios could be presented graphically and dramatically without any change of MELCOR inputs. GUI development as a part of a severe accident management program package, MIDAS. (author)

  9. Mokken scaling of the Myocardial Infarction Dimensional Assessment Scale (MIDAS).

    Science.gov (United States)

    Thompson, David R; Watson, Roger

    2011-02-01

    The purpose of this study was to examine the hierarchical and cumulative nature of the 35 items of the Myocardial Infarction Dimensional Assessment Scale (MIDAS), a disease-specific health-related quality of life measure. Data from 668 participants who completed the MIDAS were analysed using the Mokken Scaling Procedure, which is a computer program that searches polychotomous data for hierarchical and cumulative scales on the basis of a range of diagnostic criteria. Fourteen MIDAS items were retained in a Mokken scale and these items included physical activity, insecurity, emotional reaction and dependency items but excluded items related to diet, medication or side-effects. Item difficulty, in item response theory terms, ran from physical activity items (low difficulty) to insecurity, suggesting that the most severe quality of life effect of myocardial infarction is loneliness and isolation. Items from the MIDAS form a strong and reliable Mokken scale, which provides new insight into the relationship between items in the MIDAS and the measurement of quality of life after myocardial infarction. © 2010 Blackwell Publishing Ltd.

  10. MIDAS questionnaire modification for a new MIDAS junior questionnaire: a clinical experience at the Neurological Institute "C. Besta".

    Science.gov (United States)

    Grazzi, L

    2004-10-01

    During the last decade researchers have begun to employ standardised methodologies to investigate the global impact of primary headaches. Disease-specific instruments have been developed to measure headache-related disability. The MIDAS questionnaire, which is the most extensively studied of these instruments, was designed to assess the overall impact of headaches over the 3 months before compilation. The MIDAS questionnaire is an optimal tool to assess headache-related disability in adults in relation to patients' daily activities. Primary headaches are a recurrent problem for children and adolescents. Forty percent of children have experienced headaches by the age of 7 years increasing to 75% by the age of 15. In a recent report we determined the suitability of the MIDAS questionnaire in its original form for assessing disability in children and adolescents suffering from different kinds of headache. This was the first step of a line of research aimed to develop a new MIDAS questionnaire adapted for young patients. In this second study the aims were: (1) to produce a new version of the MIDAS questionnaire specific for young patients suffering from different forms of headache; (2) to assess the reliability of this new instrument; (3) to assess its sensitivity to treatment intervention.

  11. Applications of MIDAS regression in analysing trends in water quality

    Science.gov (United States)

    Penev, Spiridon; Leonte, Daniela; Lazarov, Zdravetz; Mann, Rob A.

    2014-04-01

    We discuss novel statistical methods in analysing trends in water quality. Such analysis uses complex data sets of different classes of variables, including water quality, hydrological and meteorological. We analyse the effect of rainfall and flow on trends in water quality utilising a flexible model called Mixed Data Sampling (MIDAS). This model arises because of the mixed frequency in the data collection. Typically, water quality variables are sampled fortnightly, whereas the rain data is sampled daily. The advantage of using MIDAS regression is in the flexible and parsimonious modelling of the influence of the rain and flow on trends in water quality variables. We discuss the model and its implementation on a data set from the Shoalhaven Supply System and Catchments in the state of New South Wales, Australia. Information criteria indicate that MIDAS modelling improves upon simplistic approaches that do not utilise the mixed data sampling nature of the data.

  12. La Nueva Ruta de la Seda y la diplomacia internacional de negocios

    Directory of Open Access Journals (Sweden)

    Daniel Lemus Delgado

    2017-12-01

    Full Text Available En el presente trabajo se analiza la diplomacia internacional de negocios en el contexto de la Nueva Ruta de la Seda, la iniciativa geoeconómica más importante del gobierno chino. Se parte del supuesto teórico de la Interdependencia Compleja de Kohane y Nye, para señalar la magnitud de los obstáculos que se deberán solventar. Asimismo, se plantea como mecanismo complementario la participación directa de actores no estatales en la resolución de los conflictos y se sugiere que las empresas chinas con una participación en los proyectos de la Nueva Ruta de la Seda intervengan directamente en defensa de sus propios intereses comerciales, sin depender de su gobierno o de la diplomacia tradicional. Se debe recurrir a la diplomacia internacional de negocios para acercar las posiciones de las partes involucradas y aumentar las probabilidades de éxito del proyecto.

  13. "Ei maksa seda isatamist väga üle ka pingutada". Lapsevanemate isapuhkusest loobumise diskursused / Marion Pajumets

    Index Scriptorium Estoniae

    Pajumets, Marion

    2007-01-01

    Lapsehoolduspuhkusest ning 2008. aasta jaanuaris rakenduvast vanemahüvitise seaduse muudatusest, mis pikendab hüvitise maksmise perioodi nelja kuu võrra ja lubab isadel seda võtta juba laste 70 päevaseks saades. Uurimus isapuhkuse kasutamisest. Tabel

  14. Development of MIDAS/SMR Input Deck for SMART

    International Nuclear Information System (INIS)

    Cho, S. W.; Oh, H. K.; Lee, J. M.; Lee, J. H.; Yoo, K. J.; Kwun, S. K.; Hur, H.

    2010-01-01

    The objective of this study is to develop MIDAS/SMR code basic input deck for the severe accidents by simulating the steady state for the SMART plant. SMART plant is an integrated reactor developed by KAERI. For the assessment of reactor safety and severe accident management strategy, it is necessary to simulate severe accidents using the MIDAS/SMR code which is being developed by KAERI. The input deck of the MIDAS/SMR code for the SMART plant is prepared to simulate severe accident sequences for the users who are not familiar with the code. A steady state is obtained and the results are compared with design values. The input deck will be improved through the simulation of the DBAs and severe accidents. The base input deck of the MIDAS/SMR code can be used to simulate severe accident scenarios after improvement. Source terms and hydrogen generation can be analyzed through the simulation of the severe accident. The information gained from analyses of severe accidents is expected to be helpful to develop the severe accident management strategy

  15. MIDAS: A Modular DNA Assembly System for Synthetic Biology.

    Science.gov (United States)

    van Dolleweerd, Craig J; Kessans, Sarah A; Van de Bittner, Kyle C; Bustamante, Leyla Y; Bundela, Rudranuj; Scott, Barry; Nicholson, Matthew J; Parker, Emily J

    2018-04-20

    A modular and hierarchical DNA assembly platform for synthetic biology based on Golden Gate (Type IIS restriction enzyme) cloning is described. This enabling technology, termed MIDAS (for Modular Idempotent DNA Assembly System), can be used to precisely assemble multiple DNA fragments in a single reaction using a standardized assembly design. It can be used to build genes from libraries of sequence-verified, reusable parts and to assemble multiple genes in a single vector, with full user control over gene order and orientation, as well as control of the direction of growth (polarity) of the multigene assembly, a feature that allows genes to be nested between other genes or genetic elements. We describe the detailed design and use of MIDAS, exemplified by the reconstruction, in the filamentous fungus Penicillium paxilli, of the metabolic pathway for production of paspaline and paxilline, key intermediates in the biosynthesis of a range of indole diterpenes-a class of secondary metabolites produced by several species of filamentous fungi. MIDAS was used to efficiently assemble a 25.2 kb plasmid from 21 different modules (seven genes, each composed of three basic parts). By using a parts library-based system for construction of complex assemblies, and a unique set of vectors, MIDAS can provide a flexible route to assembling tailored combinations of genes and other genetic elements, thereby supporting synthetic biology applications in a wide range of expression hosts.

  16. Mida tegi Moskva linnavalitsuse lennuk Tallinnas? / Lauri Birkan

    Index Scriptorium Estoniae

    Birkan, Lauri

    2009-01-01

    9. oktoobril 2009 maandus Tallinna lennuväljale lennuk registriga VQ-BBS, küljel kiri Airline of the Moscow Government. Vastust küsimusele, mida tegi Moskva linnavalitsuse lennuk Tallinnas, ei saanud autor ei Tallinna lennujaamast, linnavalitsusest ega ka välisministeeriumist

  17. HIT-6 and MIDAS as measures of headache disability in a headache referral population.

    Science.gov (United States)

    Sauro, Khara M; Rose, Marianne S; Becker, Werner J; Christie, Suzanne N; Giammarco, Rose; Mackie, Gordon F; Eloff, Arnoldas G; Gawel, Marek J

    2010-03-01

    The objective of this study was to compare the headache impact test (HIT-6) and the migraine disability assessment scale (MIDAS) as clinical measures of headache-related disability. The degree of headache-related disability is an important factor in treatment planning. Many quality of life and headache disability measures exist but it is unclear which of the available disability measures is the most helpful in planning and measuring headache management. We compared HIT-6 and MIDAS scores from 798 patients from the Canadian Headache Outpatient Registry and Database (CHORD). Correlation and regression analyses were used to examine the relationships between the HIT-6 and MIDAS total scores, headache frequency and intensity, and Beck Depression Inventory (BDI-II) scores. A positive correlation was found between HIT-6 and MIDAS scores (r = 0.52). The BDI-II scores correlated equally with the HIT-6 and the MIDAS (r = 0.42). There was a non-monotonic relationship between headache frequency and the MIDAS, and a non-linear monotonic relationship between headache frequency and the HIT-6 (r = 0.24). The correlation was higher between the intensity and the HIT-6 scores (r = 0.46), than MIDAS (r = 0.26) scores. Seventy-nine percent of patients fell into the most severe HIT-6 disability category, compared with the 57% of patients that fell into the most severe MIDAS disability category. Significantly more patients were placed in a more severe category with the HIT-6 than with the MIDAS (McNemar chi-square = 191 on 6 d.f., P MIDAS appear to measure headache-related disability in a similar fashion. However, some important differences may exist. Headache intensity appears to influence HIT-6 score more than the MIDAS, whereas the MIDAS was influenced more by headache frequency. Using the HIT-6 and MIDAS together may give a more accurate assessment of a patient's headache-related disability.

  18. Kui seda mammit seal jalus ei oleks... / Indrek Pajo, Heiti Riisberg, Jaana Liigand... [jt.

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele, mida peaks noor keskjuht juhtimise osas tegema kui tunneb pärast paarikuist töötamist üha rohkem, et mõned tema alluvad, kes on temast oluliselt vanemad, töötavad talle vastu, vastavad endine Cleaner Ehitus vanemobjektijuht Indrek Pajo, Trigon Kapital pensioni- ja aktsiafondide eest hoolitsev Heiti Riisberg, konsultatsioonifirma Arikano omanik ja juht Jaana Liigand, Pharmadule OÜ personali- ja büroojuht Helen Neeve, Saku Õlletehase brändide Rock ja Carlsberg juht Karin Golubev ning Kaamos Kinnisvara juht Priit Uustulnd

  19. A MARS and MIDAS Linked Accident Simulation for Large LOCA in APR1400

    International Nuclear Information System (INIS)

    Choi, Young; Kim, K. R.; Kim, D. H.; Chung, B. D.

    2006-01-01

    A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. The objectives of this paper are to explain how to identify the MAR-MIDAS linked calculation outlines and the technical problems, including the MARS data transfer method, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables

  20. Development of the GUI environments of MIDAS code for convenient input and output processing

    International Nuclear Information System (INIS)

    Kim, K. L.; Kim, D. H.

    2003-01-01

    MIDAS is being developed at KAERI as an integrated Severe Accident Analysis Code with easy model modification and addition by restructuring the data transfer scheme. In this paper, the input file management system, IEDIT and graphic simulation system, SATS, are presented as MIDAS input and output GUI systems. These two systems would form the basis of the MIDAS GUI system for input and output processing, and they are expected to be useful tools for severe accidents analysis and simulation

  1. Scientific applications and numerical algorithms on the midas multiprocessor system

    International Nuclear Information System (INIS)

    Logan, D.; Maples, C.

    1986-01-01

    The MIDAS multiprocessor system is a multi-level, hierarchial structure designed at the Advanced Computer Architecture Laboratory of the University of California's Lawrence Berkeley Laboratory. A two-stage, 11-processor system has been operational for over a year and is currently undergoing expansion. It has been employed to investigate the performance of different methods of decomposing various problems and algorithms into a multiprocessor environment. The results of such tests on a variety of applications such as scientific data analysis, Monte Carlo calculations, and image processing, are discussed. Often such decompositions involve investigating the parallel structure of fundamental algorithms. Several basic algorithms dealing with random number generation, matrix diagonalization, fast Fourier transforms, and finite element methods in solving partial differential equations are also discussed. The performance and projected extensibilities of these decompositions on the MIDAS system are reported

  2. Operating system considerations in the multiprocessor MIDAS environment

    International Nuclear Information System (INIS)

    Weaver, D.; Maples, C.; Meng, J.; Rathbun, W.

    1983-01-01

    The operating system for MIDAS provides interfaces for custom hardware, debugging facilities, and run time support. The MIDAS architecture uses various specialized hardware devices for controlling the multiple processors and to achieve high I/O throughput. The operating system interfaces with the custom hardware for diagnostics, problem setup, and loading the processors with user code. After the code is loaded, a debugging facility may be used to examine or modify the program in any of the processors, or all the processors simultaneously. During execution of the code, the operating system monitors the processors for exceptional conditions, detects hardware failures, and gathers statistics on performance. This performance information includes histograms depicting instruction execution frequency and analysis of data flow

  3. Nutritional value of silk flower hay for lambs Valor nutritional do feno de flor-de-seda para cordeiros

    Directory of Open Access Journals (Sweden)

    Aderbal Marcos de Azevêdo Silva

    2010-12-01

    Full Text Available It was evaluated four levels of silk flower (Calotropis procera S.W. hay (SFH as a substitute of sorghum (Sorghum bicolor hay (SBH in diet for lambs. Nutritional value of silk-flower hay was determined based on aparent digestibility and on metabolic, productive and economical performance of Santa Inês lambs. It was used twenty-four castrated males at 15.72 ± 1.92 kg body weight randomly distributed in four diets with silk-fklower and sorghum hay ratios (100:0, 66:33, 33:66, 0:100, and supplemented with a concentrate mixture based on 50% roughage:50% concentrate (weight/weight. Increase in the levels of silk-flower hay in the diet reduced weight gain and nutrient intake and it increased feed conversion and digestibility coeficients of all the nutrients. Nitrogen balance was similar in all levels of silk-flower hay, although there was a tendency of reduction in nitrogen retention at levels 66% and 100% of silk-flower hay. At the levels 0 and 33% of silk-flower hay in the diet, dry matter ingestion (170 and 180 g/day, daily average weight gain (84 and 89 g/kg0.75and feed conversion (4.99 and 5.02 were satisfactory. Silk-flower hay can represent up to 16.5% of the total food ingestion or 33% of the roughage in diet for lambs.Avaliaram-se quatro níveis de feno de flor-de-seda (Calotropis procera S.W. em substituição ao feno de sorgo (Sorghum bicolor na dieta de cordeiros. O valor nutricional do feno de flor-de-seda foi determinado com base na digestibilidade aparente e no desempenho metabólico, produtivo e econômico de cordeiros Santa Inês. Utilizaram-se 24 machos castrados com peso corporal de 15,72 kg ± 1,92 kg distribuídos aleatoriamente em quatro dietas com relações entre feno de flor-de-seda e de sorgo (100:0, 66:33, 33:66 e 0:100 e suplementadas com uma mistura concentrada à base de 50% de volumos e 50% de concentrado (peso/peso. O aumento nos níveis de feno de flor-de-seda na dieta diminuiu o ganho de peso e a ingestão de

  4. Mida tegi peaminister Ansip 20 aastat tagasi? / Tarmo Vahter

    Index Scriptorium Estoniae

    Vahter, Tarmo, 1970-

    2007-01-01

    Endine Tartu KEK-i juhataja Jaak Kalm ja Tartu linna täitevkomitee aseesimees Robert Närska 1988. a. 2. veebruari meeleavaldusest ja selle laialiajamisest Tartus. Andrus Ansipi väidetavast kommentaarist meeleavalduse laialiajamisel. Peaminister Andrus Ansipi vastuseid küsimustele, miks EKP Tartu rajoonikomitee ei valinud teda 1988. a. rajoonikomitee II sekretäriks; kus ta viibis 2. veebruaril 1988. Lisa: Mida näitavad dokumendid

  5. Ilves : mida põrgut teeb Venemaa G8-s?

    Index Scriptorium Estoniae

    2007-01-01

    President Toomas Hendrik Ilves viibis Prahas 4. ja 5. juunil 2007 toimunud konverentsil "Demokraatia ja julgeolek", kus ta seadis kahtluse alla selle, kas Euroopat rakettidega ähvardava Venemaa koht on ikka G8-s ja Euroopa Nõukogus. Ilmunud ka: Eesti Elu 8. juuni 2007, lk. 1,4, pealk.: Mida teeb Venemaa G8-s?, ingl. k. lk. 9, pealk.: Ilves: what is Russia doing in the G8? Vabariigi President töövisiidil Prahasse 4.-6.06.2007

  6. Operation and maintenance manual for data acquisition system of MIDAS

    International Nuclear Information System (INIS)

    Lee, D. Y.; Park, W. M.; Kim, J. T.; Euh, D. J.

    2001-09-01

    This report describes an operation and maintenance manual of the data acquisition system and the data processing system for the DVI performance evaluation facility, MIDAS. The data acquisition system is implemented with VXI based system of Kinetic Systems TM , and the data processing PC. This report presents the configuration method and operation procedure for the operator. The modification procedure and method for functional extension and performance modification are also included for the future demand

  7. Microwave detection of air showers with the MIDAS experiment

    International Nuclear Information System (INIS)

    Privitera, Paolo; Alekotte, I.; Alvarez-Muniz, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Facal San Luis, P.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Reyes, L.C.; Rouille d'Orfeuil, B.; Santos, E.M.; Wayne, S.; Williams, C.

    2011-01-01

    Microwave emission from Extensive Air Showers could provide a novel technique for ultra-high energy cosmic rays detection over large area and with 100% duty cycle. We describe the design, performance and first results of the MIDAS (MIcrowave Detection of Air Showers) detector, a 4.5 m parabolic dish with 53 feeds in its focal plane, currently installed at the University of Chicago.

  8. MIDA - Optimizing control room performance through multi-modal design

    International Nuclear Information System (INIS)

    Ronan, A. M.

    2006-01-01

    Multi-modal interfaces can support the integration of humans with information processing systems and computational devices to maximize the unique qualities that comprise a complex system. In a dynamic environment, such as a nuclear power plant control room, multi-modal interfaces, if designed correctly, can provide complementary interaction between the human operator and the system which can improve overall performance while reducing human error. Developing such interfaces can be difficult for a designer without explicit knowledge of Human Factors Engineering principles. The Multi-modal Interface Design Advisor (MIDA) was developed as a support tool for system designers and developers. It provides design recommendations based upon a combination of Human Factors principles, a knowledge base of historical research, and current interface technologies. MIDA's primary objective is to optimize available multi-modal technologies within a human computer interface in order to balance operator workload with efficient operator performance. The purpose of this paper is to demonstrate MIDA and illustrate its value as a design evaluation tool within the nuclear power industry. (authors)

  9. Compass cues used by a nocturnal bull ant, Myrmecia midas.

    Science.gov (United States)

    Freas, Cody A; Narendra, Ajay; Cheng, Ken

    2017-05-01

    Ants use both terrestrial landmarks and celestial cues to navigate to and from their nest location. These cues persist even as light levels drop during the twilight/night. Here, we determined the compass cues used by a nocturnal bull ant, Myrmecia midas , in which the majority of individuals begin foraging during the evening twilight period. Myrmecia midas foragers with vectors of ≤5   m when displaced to unfamiliar locations did not follow the home vector, but instead showed random heading directions. Foragers with larger home vectors (≥10   m) oriented towards the fictive nest, indicating a possible increase in cue strength with vector length. When the ants were displaced locally to create a conflict between the home direction indicated by the path integrator and terrestrial landmarks, foragers oriented using landmark information exclusively and ignored any accumulated home vector regardless of vector length. When the visual landmarks at the local displacement site were blocked, foragers were unable to orient to the nest direction and their heading directions were randomly distributed. Myrmecia midas ants typically nest at the base of the tree and some individuals forage on the same tree. Foragers collected on the nest tree during evening twilight were unable to orient towards the nest after small lateral displacements away from the nest. This suggests the possibility of high tree fidelity and an inability to extrapolate landmark compass cues from information collected on the tree and at the nest site to close displacement sites. © 2017. Published by The Company of Biologists Ltd.

  10. CACTÁCEAS NATIVAS ASSOCIADAS A FENOS DE FLOR DE SEDA E SABIÁ NA ALIMENTAÇÃO DE BORREGOS

    Directory of Open Access Journals (Sweden)

    JOSÉ GERALDO MEDEIROS DA SILVA

    2010-01-01

    Full Text Available The objective of this study was to evaluate the utilization effects of two native cacti named mandacaru (Cereus jamacaru DC. and xiquexique [Pilosocereus gounellei (A. Weber ex K. Schum. Bly ex Rowl.] associated with sabiá (Mimosa caesalpiniifolia Benth. and flor de seda (Calotropis procera (Ait. R.Br. about the nutrient intake, daily weight gain, and feed conversion in sheep feedlot. Twenty Morada Nova male hair sheep with an average weight of 15.40, were allocated in a randomized block design, with four treatments and five replicates. The experimental treatments consisted of four diets (30% native cacti + 30% shrub hay + 40% concentrate, on dry matter basis: T1- xiquexique + sabiá hay; T2- xiquexique + flor de seda hay; T3- mandacaru + sabiá hay e T4- mandacaru + flor-de-seda hay. The concentrate consisted of 100.0% algaroba (Prosopis juliflora (Sw DC pods. No significant difference was observed for daily weight gain which averaged 88.77 g, and also for voluntary intakes of dry matter, organic matter, ether extract, total carbohydrates, nonfiber carbohydrates, total digestible nutrients and digestible energy in relation to g/day, %BW and g/kg0.75. Significant differences were observed for intake of water in g/day.

  11. Transcriptomics of morphological color change in polychromatic Midas cichlids.

    Science.gov (United States)

    Henning, Frederico; Jones, Julia C; Franchini, Paolo; Meyer, Axel

    2013-03-13

    Animal pigmentation has received much attention in evolutionary biology research due to its strong implications for adaptation and speciation. However, apart from a few cases the genetic changes associated with these evolutionary processes remain largely unknown. The Midas cichlid fish from Central America are an ideal model system for investigating pigmentation traits that may also play a role in speciation. Most Midas cichlids maintain their melanophores and exhibit a grayish (normal) color pattern throughout their lives. A minority of individuals, however, undergo color change and exhibit a distinctive gold or even white coloration in adulthood. The ontogenetic color change in the Midas cichlids may also shed light on the molecular mechanisms underlying pigmentation disorders in humans. Here we use next-generation sequencing (Illumina) RNAseq analyses to compare skin transcriptome-wide expression levels in three distinct stages of color transformation in Midas cichlids. cDNA libraries of scale tissue, for six biological replicates of each group, were generated and sequenced using Illumina technology. Using a combination of three differential expression (DE) analyses we identified 46 candidate genes that showed DE between the color morphs. We find evidence for two key DE patterns: a) genes involved in melanosomal pathways are up-regulated in normally pigmented fish; and b) immediate early and inflammatory response genes were up-regulated in transitional fish, a response that parallels some human skin disorders such as melanoma formation and psoriasis. One of the DE genes segregates with the gold phenotype in a genetic cross and might be associated with incipient speciation in this highly "species-rich" lineage of cichlids. Using transcriptomic analyses we successfully identified key expression differences between different color morphs of Midas cichlid fish. These differentially expressed genes have important implications for our understanding of the molecular

  12. MIDAS: a database-searching algorithm for metabolite identification in metabolomics.

    Science.gov (United States)

    Wang, Yingfeng; Kora, Guruprasad; Bowen, Benjamin P; Pan, Chongle

    2014-10-07

    A database searching approach can be used for metabolite identification in metabolomics by matching measured tandem mass spectra (MS/MS) against the predicted fragments of metabolites in a database. Here, we present the open-source MIDAS algorithm (Metabolite Identification via Database Searching). To evaluate a metabolite-spectrum match (MSM), MIDAS first enumerates possible fragments from a metabolite by systematic bond dissociation, then calculates the plausibility of the fragments based on their fragmentation pathways, and finally scores the MSM to assess how well the experimental MS/MS spectrum from collision-induced dissociation (CID) is explained by the metabolite's predicted CID MS/MS spectrum. MIDAS was designed to search high-resolution tandem mass spectra acquired on time-of-flight or Orbitrap mass spectrometer against a metabolite database in an automated and high-throughput manner. The accuracy of metabolite identification by MIDAS was benchmarked using four sets of standard tandem mass spectra from MassBank. On average, for 77% of original spectra and 84% of composite spectra, MIDAS correctly ranked the true compounds as the first MSMs out of all MetaCyc metabolites as decoys. MIDAS correctly identified 46% more original spectra and 59% more composite spectra at the first MSMs than an existing database-searching algorithm, MetFrag. MIDAS was showcased by searching a published real-world measurement of a metabolome from Synechococcus sp. PCC 7002 against the MetaCyc metabolite database. MIDAS identified many metabolites missed in the previous study. MIDAS identifications should be considered only as candidate metabolites, which need to be confirmed using standard compounds. To facilitate manual validation, MIDAS provides annotated spectra for MSMs and labels observed mass spectral peaks with predicted fragments. The database searching and manual validation can be performed online at http://midas.omicsbio.org.

  13. SeDA: A software package for the statistical analysis of the instrument drift

    International Nuclear Information System (INIS)

    Lee, H. J.; Jang, S. C.; Lim, T. J.

    2006-01-01

    The setpoints for safety-related equipment are affected by many sources of an uncertainty. ANSI/ISA-S67.04.01-2000 [1] and ISA-RP6 7.04.02-2000 [2] suggested the statistical approaches for ensuring that the safety-related instrument setpoints were established and maintained within the technical specification limits [3]. However, Jang et al. [4] indicated that the preceding methodologies for a setpoint drift analysis might be insufficient to manage a setpoint drift on an instrumentation device and proposed new statistical analysis procedures for the management of a setpoint drift, based on the plant specific as-found/as-left data. Although IHPA (Instrument History Performance Analysis) is a widely known commercial software package to analyze an instrument setpoint drift, several steps in the new procedure cannot be performed by using it because it is based on the statistical approaches suggested in the ANSI/ISA-S67.04.01 -2000 [1] and ISA-RP67.04.02-2000 [2], In this paper we present a software package (SeDA: Setpoint Drift Analysis) that implements new methodologies, and which is easy to use, as it is accompanied by powerful graphical tools. (authors)

  14. A preliminary psychometric evaluation of Music in Dementia Assessment Scales (MiDAS).

    Science.gov (United States)

    McDermott, Orii; Orgeta, Vasiliki; Ridder, Hanne Mette; Orrell, Martin

    2014-06-01

    Music in Dementia Assessment Scales (MiDAS), an observational outcome measure for music therapy with people with moderate to severe dementia, was developed from qualitative data of focus groups and interviews. Expert and peer consultations were conducted at each stage of the scale development to maximize its content validity. This study aimed to evaluate the psychometric properties of MiDAS. Care home residents with dementia attended weekly group music therapy for up to ten sessions. Music therapists and care home staff were requested to complete weekly MiDAS ratings. The Quality of Life Scale (QoL-AD) was completed at three time-points. A total of 629 (staff = 306, therapist = 323) MiDAS forms were completed. The statistical analysis revealed that MiDAS has high therapist inter-rater reliability, low staff inter-rater reliability, adequate staff test-retest reliability, adequate concurrent validity, and good construct validity. High factor loadings between the five MiDAS Visual Analogue Scale (VAS) items, levels of Interest, Response, Initiation, Involvement, and Enjoyment, were found. This study indicates that MiDAS has good psychometric properties despite the small sample size. Future research with a larger sample size could provide a more in-depth psychometric evaluation, including further exploration of the underlying factors. MiDAS provides a measure of engagement with musical experience and offers insight into who is likely to benefit on other outcomes such as quality of life or reduction in psychiatric symptoms.

  15. Beyond topography - enhanced imaging of cometary dust with the MIDAS AFM

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.

    2013-09-01

    The MIDAS atomic force microscope (AFM) onboard the Rosetta spacecraft is primarily designed to return the 3D shape and structure of cometary dust particles collected at comet 67P/Churyumov-Gerasimenko [1]. Commercial AFMs have, however, been further developed to measure many other sample properties. The possibilities to make such measurements with MIDAS are explored here.

  16. Nimetage mõned suuremad nõmedused, mida üks ülemus teha saab? / Kairi Ütsmüts, Allan Rosenberg, Katriin Jüriska ... [jt.

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele vastavad Swedbank Eesti infotehnoloogia projektijuht Kairi Ütsmüts, Aspiro Eesti müügijuht Allan Rosenberg, Uuskasutuskeskuse tegevjuht Katriin Jüriska, Tele2 toote- ja turundusjuht Reilika Ilp, GrabCAD'i omanik ja insener Indrek Narusk ning turismifirma Estfly omanik Vahur Mäe

  17. The Activities and Attitudes of Armenian-Georgian Troops which Affected the Course of Kösedağ War

    Directory of Open Access Journals (Sweden)

    Mehmet ÖZMENLİ

    2014-12-01

    Full Text Available The events which occurred during the course of the War of Kösedağ at which the Seljuk Empire of Turkey met the armies under the command of the Mongolian Baycu Noyan are one of the major happenings to be examined in terms of their consequences, ever recorded in Turkish History. Prior to the war, the Seljuks of Turkey were traumatized because of internal rebellions. The Mongol Army gained an easy victory because of the incorrect decisions made Sultan Gıyaseddin Kaykhusraw II from the beginning of the war and of the negative roles of those involved in the war. Anatolia, which was like paradise and whose inhabitants experienced a kind of idyllic bliss and happiness under the administration of The Seljuks, was invaded by the Mongolian army, which advanced facing no resistance and caused mischief on the earth. The sources concerned indicate that the relationship between the Turks, the Armenians and the Georgians coincided with the entrance of the Seljuks into Anatolia. The Armenians, who lived under oppression and tyranny under the administration of the Byzantine Empire, met and viewed the Seljucks as their liberators. However, the Christians during the Crusades provoked and instigated both the Armenians and sometimes the Georgians against the Turks. The Armenians, who captured the Çukurova Region with the help of the Crusaders, established a barony here. During the reign of Alaeddin Keykubâd and İzzeddin Keykavus, the Sultans of the Seljuks of Turkey, the Seljuks made the Armenians subjected to them, but the Armenians did not keep their promise during the war of Kösedağ in 1243. The study focuses on the effects of the course of Armenian and Georgian forces, which played a role in the War of Kösedağ, upon the course of the war. The study also deals, in brief, with the role the statesmen of the Seljuks played in the defeat. Different historical sources written in such various languages as Arabic, Syrian, Armenian, Persian and Georgian on the

  18. The European Southern Observatory-MIDAS table file system

    Science.gov (United States)

    Peron, M.; Grosbol, P.

    1992-01-01

    The new and substantially upgraded version of the Table File System in MIDAS is presented as a scientific database system. MIDAS applications for performing database operations on tables are discussed, for instance, the exchange of the data to and from the TFS, the selection of objects, the uncertainty joins across tables, and the graphical representation of data. This upgraded version of the TFS is a full implementation of the binary table extension of the FITS format; in addition, it also supports arrays of strings. Different storage strategies for optimal access of very large data sets are implemented and are addressed in detail. As a simple relational database, the TFS may be used for the management of personal data files. This opens the way to intelligent pipeline processing of large amounts of data. One of the key features of the Table File System is to provide also an extensive set of tools for the analysis of the final results of a reduction process. Column operations using standard and special mathematical functions as well as statistical distributions can be carried out; commands for linear regression and model fitting using nonlinear least square methods and user-defined functions are available. Finally, statistical tests of hypothesis and multivariate methods can also operate on tables.

  19. A restructuring of CF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2004-01-01

    CF package, which evaluates user-specified 'control functions' and applies them to define or control various aspects of computation, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and modernized data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the CF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory, difficulty is more over because its data is location information of other package's data due to characteristics of CF package. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the CF package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The verification has been done by comparing the results of the modified code with those from the existing code. As the trends are similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  20. A restructuring of RN1 package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Kim, K. R.

    2003-01-01

    RN1 package, which is one of two fission product-related packages in MELCOR, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and modernized data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the RN1 package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN1 package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The verification has been done by comparing the results of the modified code with those from the existing code. As the trends are similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  1. MIDAS: Lessons learned from the first spaceborne atomic force microscope

    Science.gov (United States)

    Bentley, Mark Stephen; Arends, Herman; Butler, Bart; Gavira, Jose; Jeszenszky, Harald; Mannel, Thurid; Romstedt, Jens; Schmied, Roland; Torkar, Klaus

    2016-08-01

    The Micro-Imaging Dust Analysis System (MIDAS) atomic force microscope (AFM) onboard the Rosetta orbiter was the first such instrument launched into space in 2004. Designed only a few years after the technique was invented, MIDAS is currently orbiting comet 67P Churyumov-Gerasimenko and producing the highest resolution 3D images of cometary dust ever made in situ. After more than a year of continuous operation much experience has been gained with this novel instrument. Coupled with operations of the Flight Spare and advances in terrestrial AFM a set of "lessons learned" has been produced, cumulating in recommendations for future spaceborne atomic force microscopes. The majority of the design could be reused as-is, or with incremental upgrades to include more modern components (e.g. the processor). Key additional recommendations are to incorporate an optical microscope to aid the search for particles and image registration, to include a variety of cantilevers (with different spring constants) and a variety of tip geometries.

  2. A restructuring of COR package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The COR package, which calculates the thermal response of the core and the lower plenum internal structures and models the relocation of the core and lower plenum structural materials, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To do this, the data transferring methods of the current MELCOR code are modified and adopted into the COR package. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as well as a waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which leads to an efficient memory treatment and an easy understanding of the code. Restructuring of the COR package addressed in this paper includes a module development, subroutine modification. The verification has been done by comparing the results of the modified code with those of the existing code. As the trends are similar to each other, it implies that the same approach could be extended to the entire code package. It is expected that the code restructuring will accelerated the code's domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  3. A restructuring of RN2 package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.

    2003-01-01

    RN2 package, which is one of two fission product-related package in MELCOR, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the RN2 package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN2 package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The validation has been done by comparing the results of the modified code with those from the existing code. As the trends are the similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  4. Reliability and Validity of the Greek Migraine Disability Assessment (MIDAS) Questionnaire.

    Science.gov (United States)

    Oikonomidi, Theodora; Vikelis, Michail; Artemiadis, Artemios; Chrousos, George P; Darviri, Christina

    2018-03-01

    The Migraine Disability Assessment (MIDAS) Questionnaire is a reliable and valid instrument for migraine-related disability. Such a tool is needed to quantify migraine-related disability in the Greek population. This validation study aims to assess the test-retest reliability, internal consistency, item discriminant and convergent validity of the Greek translation of the MIDAS. Adults diagnosed with migraine completed the MIDAS Questionnaire on two occasions 3 weeks apart to assess reliability, and completed the RAND-36 to assess validity. Participants (n = 152) had a median MIDAS score of 24 and mostly severe disability (58% were grade IV). The test-retest reliability analysis (N = 59) revealed excellent reliability for the total score. Internal consistency was α = 0.71 for initial and α = 0.82 for retest completion. For item discriminant validity, the correlations between each question and the total score were significant, with high correlations for questions 2-5 (range 0.67 ≤ r ≤ 0.79; p MIDAS score tended to have better wellbeing. Psychometric properties are comparable with those of other published validation studies of the MIDAS and the original. Findings on question 1 show that missing work/school days may be closely related with increased affect issues. The Greek version of the MIDAS Questionnaire has good reliability and validity. This study allowed for cross-cultural comparability of research findings.

  5. Reliability and validity of migraine disability assessment questionnaire-Thai version (Thai-MIDAS).

    Science.gov (United States)

    Seethong, Piman; Nimmannit, Akarin; Chaisewikul, Rungsan; Prayoonwiwat, Naraporn; Chotinaiwattarakul, Wattanachai

    2013-02-01

    To assess the validity and test-retest reliability of a Thai translation of the Migraine Disability Assessment (MIDAS) Questionnaire in Thai patients with migraine. Migraineurs from the Headache Clinic in Siriraj Hospital were recruited and asked to complete a 13-weeks diary and answered the Thai-MIDAS at once. Some participants were asked to provide the 2nd Thai-MIDAS in the next 2 weeks for test-retest reliability. Ninety-three patients had completed the 13-weeks diaries. Age range was 18-58 years with mean 37.69 +/- 9.60 years. All 5 items and the total score of Thai-MIDAS were moderately correlated with data from 13-weeks diary (Spearman's correlation coefficient = 0.32-0.62). The test-retest reliability of the total score of Thai-MIDAS in 30 patients demonstrated a highly reliable degree of intraclass correlation (ICC = 0.76, 95% CI 0.49-0.88). The present study reveals that the Thai-MIDAS has satisfactory validity and reliability in comparison with the original English MIDAS version.

  6. Como a poliamida substituiu a seda: uma história da descoberta da poliamida 66

    Directory of Open Access Journals (Sweden)

    Roberto Filippini Fantoni

    2012-01-01

    Full Text Available Existem muitas substâncias que fizeram a história do século XX e contribuíram para os grandes desenvolvimentos queaconteceram durante esse longo período. Muitas destas substâncias foram descobertas por acidente ("serendipity" a caminho de pesquisa diferente e existem muitos casos de que nós poderíamos mencionar em especial na área de produtos químicos e polímeros. Mas não foi exatamente assim na história do nylon que estamos para contar, porque nesse caso foi o desejo de encontrar uma alternativa para a seda, o impulso para obter um substituto daquela fibra natural maravilhosa que só a natureza é capaz de sintetizar através de sínteses tanto difícil quanto precisas e rápidas e com métodos ainda a considerar se não inatingíveis certamente ainda não alcançados. O autor desse texto, deve ao polímero do qual vamos falar a história da própria vida científico-tecnológica e, por consequência, encontra-se em uma situação psicológica que o levará a empregar demasiada ênfase, mas pelo menos com conhecimento de causa. Podemos desculpar os excessos e a extensão do texto, incomum para esta revista. Muitas das informações históricas foram encontradas na internet; outra importante fonte informativa foi um livro intitulado "Os botões de Napoleão" que fala de 17 moléculas que mudaram o mundo e o nylon é uma dessas. Esperamos que os leitores sintam-se agradavelmente envolvidos por esta história.

  7. Iniciativa municipal para la fundación de una fábrica de seda : Guadalajara (1631-1641

    Directory of Open Access Journals (Sweden)

    Ángel Mejía Asensio

    1995-01-01

    Full Text Available A pesar del evidente deseo de la ciudad de Guadaiajara de crear una fábrica de seda que posibilitara el aumento de su población, en progresiva disminución desde fines del siglo xvi, hay que decir que fue un total fracaso, aunque, en un principio, el tiempo en que debió funcionar esta fábrica (1631-1633, se alcanzó uno de los objetivos previstos: la llegada de nuevos habitantes a la ciudad. La causa principal de este fracaso la encontramos en el incumplimiento del contrato por parte de los sederos portugueses que convirtieron esta fábrica de seda en jabonería. Ni siquiera el posterior funcionamiento de la fábrica de jabón sirvió para aliviar los problemas a los que se enfrentaba Guadaiajara: su escasa población, viendo cómo se marchaban sus recientes convecinos, y el alto precio que pagaba por el encabezamiento de sus alcabalas. Aunque hay que reconocer que el funcionamiento de la jabonería vino a paliar la falta de este producto en la zona, al mismo tiempo que se obtenía un abaratamiento importante del mismo.

  8. Accuracy Potential and Applications of MIDAS Aerial Oblique Camera System

    Science.gov (United States)

    Madani, M.

    2012-07-01

    Airborne oblique cameras such as Fairchild T-3A were initially used for military reconnaissance in 30s. A modern professional digital oblique camera such as MIDAS (Multi-camera Integrated Digital Acquisition System) is used to generate lifelike three dimensional to the users for visualizations, GIS applications, architectural modeling, city modeling, games, simulators, etc. Oblique imagery provide the best vantage for accessing and reviewing changes to the local government tax base, property valuation assessment, buying & selling of residential/commercial for better decisions in a more timely manner. Oblique imagery is also used for infrastructure monitoring making sure safe operations of transportation, utilities, and facilities. Sanborn Mapping Company acquired one MIDAS from TrackAir in 2011. This system consists of four tilted (45 degrees) cameras and one vertical camera connected to a dedicated data acquisition computer system. The 5 digital cameras are based on the Canon EOS 1DS Mark3 with Zeiss lenses. The CCD size is 5,616 by 3,744 (21 MPixels) with the pixel size of 6.4 microns. Multiple flights using different camera configurations (nadir/oblique (28 mm/50 mm) and (50 mm/50 mm)) were flown over downtown Colorado Springs, Colorado. Boresight fights for 28 mm nadir camera were flown at 600 m and 1,200 m and for 50 mm nadir camera at 750 m and 1500 m. Cameras were calibrated by using a 3D cage and multiple convergent images utilizing Australis model. In this paper, the MIDAS system is described, a number of real data sets collected during the aforementioned flights are presented together with their associated flight configurations, data processing workflow, system calibration and quality control workflows are highlighted and the achievable accuracy is presented in some detail. This study revealed that the expected accuracy of about 1 to 1.5 GSD (Ground Sample Distance) for planimetry and about 2 to 2.5 GSD for vertical can be achieved. Remaining systematic

  9. ACCURACY POTENTIAL AND APPLICATIONS OF MIDAS AERIAL OBLIQUE CAMERA SYSTEM

    Directory of Open Access Journals (Sweden)

    M. Madani

    2012-07-01

    Full Text Available Airborne oblique cameras such as Fairchild T-3A were initially used for military reconnaissance in 30s. A modern professional digital oblique camera such as MIDAS (Multi-camera Integrated Digital Acquisition System is used to generate lifelike three dimensional to the users for visualizations, GIS applications, architectural modeling, city modeling, games, simulators, etc. Oblique imagery provide the best vantage for accessing and reviewing changes to the local government tax base, property valuation assessment, buying & selling of residential/commercial for better decisions in a more timely manner. Oblique imagery is also used for infrastructure monitoring making sure safe operations of transportation, utilities, and facilities. Sanborn Mapping Company acquired one MIDAS from TrackAir in 2011. This system consists of four tilted (45 degrees cameras and one vertical camera connected to a dedicated data acquisition computer system. The 5 digital cameras are based on the Canon EOS 1DS Mark3 with Zeiss lenses. The CCD size is 5,616 by 3,744 (21 MPixels with the pixel size of 6.4 microns. Multiple flights using different camera configurations (nadir/oblique (28 mm/50 mm and (50 mm/50 mm were flown over downtown Colorado Springs, Colorado. Boresight fights for 28 mm nadir camera were flown at 600 m and 1,200 m and for 50 mm nadir camera at 750 m and 1500 m. Cameras were calibrated by using a 3D cage and multiple convergent images utilizing Australis model. In this paper, the MIDAS system is described, a number of real data sets collected during the aforementioned flights are presented together with their associated flight configurations, data processing workflow, system calibration and quality control workflows are highlighted and the achievable accuracy is presented in some detail. This study revealed that the expected accuracy of about 1 to 1.5 GSD (Ground Sample Distance for planimetry and about 2 to 2.5 GSD for vertical can be achieved. Remaining

  10. Abiks algajatele anarhistidele / Ants Juske

    Index Scriptorium Estoniae

    Juske, Ants, 1956-2016

    2000-01-01

    Moskvas kirjastuselt "Gileia" 1999. a. ilmunud Aleksandr Breneri ja Barbara Schurzi raamatust "Mida teha? 54 tehnoloogiat kultuuriliseks vastupanuks võimusuhetele hilises kapitalismis". Vastupanu Eestis

  11. ANTONIO DE MONTSERRAT – LA RUTA DE LA SEDA Y LOS CAMINOS SECRETOS DEL TANTRA

    Directory of Open Access Journals (Sweden)

    Oscar R. Gómez

    2016-01-01

    Full Text Available En este artículo se presenta la biografía de Antonio de Monserrat con el objeto de insertar en el pensamiento crítico budista a quien se considera el primer occidental iniciado en la filosofía tántrica e impulsor de ésta en Occidente a través de la Compañía de Jesús. Para ello, primero se hace un recorrido histórico que pone en foco cómo el budismo es desplazado de la India y se refugia entre las poblaciones de Asia central como la etnia Uigur en la actual Turquestán, cómo es adoptado por los emperadores chinos y se expande a lo largo de toda la Ruta de la Seda. La combinación del budismo indio con influencias occidentales (grecobudismo dio origen a diversas escuelas budistas en Asia Central y en China. Luego se caracteriza en forma sintética la versión esotérica que adquiere el budismo (el tantra y que se consolida en el siglo VIII en el Tíbet como budismo vajrayana (tántrico. Ésta es la forma de budismo que toman los gobernantes, que promueve la igualdad completa de personas y género, la idea del sujeto como una construcción de la cultura y la noción de deidades metafóricas —útiles para modelar el carácter de las personas pero de absoluta inexistencia— además del postulado budista de verdad relativa. Esta visión no teísta —o transteísta, como Gómez la prefiere llamar— se reflejaba en la total tolerancia religiosa del imperio Chino, Uigur y Mongol, que garantizaba la seguridad y el libre intercambio por la Ruta de la Seda. Es esta visión de sujetos no divididos en castas ni diferenciados por sangre lo que maravilla a de Montserrat al decir que los tibetanos “no tienen reyes entre sí” e inflama la avidez de quienes viajaron especialmente (a partir de los escritos de éste a iniciarse en el budismo tántrico tibetano como los jesuitas Antonio de Andrade y Juan de Brito. El tercer apartado se dedica de lleno a la biografía de Antonio de Monserrat y a precisar su contacto con el tantra. Abstract This

  12. Oh seda Eesti elu! : väljavõte Eesti Ekspressi kõige kummalisematest uudistest aastal 2002 : Rahvusraamatukogu ostis 1000 dollari eest tasuta raamatu

    Index Scriptorium Estoniae

    2003-01-01

    RR tellis USA firmalt Rector Press raamatu "Estonian Companies Handbook 2001", selgus, et tegemist on AS Connectuse kirjastatava eestikeelse kataloogiga "KOMPASS Eesti TOP Firmad 2001", mida oleks võinud saada tasuta

  13. A revision of the Anthaxia (Anthaxia) midas Kiesenwetter, 1857 species-group (Coleoptera: Buprestidae: Anthaxiini).

    Science.gov (United States)

    Baiocchi, Daniele; Magnani, Gianluca

    2018-01-10

    The Anthaxia (Anthaxia) midas Kiesenwetter, 1857 species-group is defined and revised. A new species from Turkey, A. (A.) cebecii sp. nov., is described and compared to its most similar species. A. midas oberthuri Schaefer, 1938 is elevated to the rank of species, and a lectotype is designated. A. (A.) spathuligera Obenberger, 1924 and A. (A.) midas muelleri Obenberger, 1925 are reconfirmed synonyms of A. midas Kiesenwetter, 1857.All species of the new species-group are illustrated, including the hitherto unknown male of A. (A.) patsyae Baiocchi, 2008, all type specimens and original data labels. In addition to diagnostic characters, informations on the distribution, biology and taxonomic position of each species are also presented, together with a short definition of the new species-group, and a key to its species.

  14. Utilizing a multiprocessor architecture - The performance of MIDAS

    International Nuclear Information System (INIS)

    Maples, C.; Logan, D.; Meng, J.; Rathbun, W.; Weaver, D.

    1983-01-01

    The MIDAS architecture organizes multiple CPUs into clusters called distributed subsystems. Each subsystem consists of an array of processors controlled by a supervisory CPU. The multiprocessor array is composed of commercial CPUs (with floating point hardware) and specialized processing elements. Interprocessor communication within the array may occur either through switched memory modules or common shared memory. The architecture permits multiple processors to be focused on single problems. A distributed subsystem has been constructed and tested. It currently consists of a supervisor CPU; 16 blocks of independently switchable memory; 9 general purpose, VAX-class CPUs; and 2 specialized pipelined processors to handle I/O. Results on a variety of problems indicate that the subsystem performs 8 to 15 times faster than a standard computer with an identical CPU. The difference in performance represents the effect of differing CPU and I/O requirements

  15. Responsiveness of migraine-ACT and MIDAS questionnaires for assessing migraine therapy.

    Science.gov (United States)

    García, María Luisa; Baos, Vicente; Láinez, Miguel; Pascual, Julio; López-Gil, Arturo

    2008-10-01

    Migraine is frequently undertreated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple and reliable tool to identify patients requiring a change in current acute migraine treatment. To investigate the responsiveness of the Migraine-ACT tool, and compare it with that of the Migraine Disability Assessment (MIDAS) questionnaire, for patients with migraine at 1100 primary care sites in Spain. Patients eligible for this open-label, 2-visit prospective study reported migraine for >1 year and >or=1 migraine attack per month and were new to the clinic or on follow-up care for MIDAS questionnaires were administered, and patient satisfaction with treatment was recorded, at baseline and at 3 months. A total of 3272 patients, 78% female, were enrolled, and 2877 (88%) returned for the 3-month visit. Investigators changed baseline migraine treatment for 72% of returning patients; 85% and 80% of these patients had improved Migraine-ACT and MIDAS scores at 3 months, respectively. Patients who reported being completely or very satisfied with migraine treatment numbered 492 (15%) at baseline and 1406 (49%) at 3 months. Migraine-ACT and MIDAS score agreement for improvement at 3 months was poor (kappa = 0.339). Both the mean MIDAS score and the distribution of Migraine-ACT scores improved over the course of 3 months; however, Migraine-ACT scores were significantly (P MIDAS scores. The area under the curve in the receiver-operating characteristic analysis was significantly (P MIDAS (0.70) questionnaire. These results suggest that the Migraine-ACT questionnaire can be used more reliably than the MIDAS questionnaire for detecting improvements in treatment of new and follow-up patients with migraine.

  16. [The psychometric properties of the Turkish version of Myocardial Infarction Dimensional Assessment Scale (MIDAS)].

    Science.gov (United States)

    Yılmaz, Emel; Eser, Erhan; Şekuri, Cevad; Kültürsay, Hakan

    2011-08-01

    The purpose of this study was to describe the psychometric properties of the Myocardial Infarction Dimensional Assessment Scale (MIDAS). This is a methodological cultural adaptation study. The MIDAS consists of 35-items covering seven domains: physical activity, insecurity, emotional reaction, dependency, diet, concerns over medication, and side effects which are rated on a five-point Likert scale from 1: never to 5:always. The highest score of MIDAS is 100.Quality of life (QOL) decreases as the score of scale increases. Overall 185 myocardial infarction (MI) patients were enrolled in this study. Cronbach alpha was used for the reliability analysis. The criterion validity, structural validity, and sensitivity analysis approach was used for validity analysis. New York Heart Association (NYHA) and the Canadian Cardiovascular Society Functional Classifications (CCSFC) for testing the criterion validity; SF-36 for construct validity testing of the Turkish version of the MIDAS were used. The range of Cronbach alpha values is 0.79-0.90 for seven domains of the scale. No problematic items were observed for the entire scale. Medication related domains of the MIDAS showed considerable floor effects (35.7%-22.7%). Confirmatory Factor analysis indicators [Comparative Fit Index (CFI) =0.95 and Root Mean Square Error of Approximation (RMSEA) =0.075] supported the construct validity of MIDAS. Convergent validity of the MIDAS was confirmed with correlation of SF-36 scale where appropriate. Criterion validity results was also satisfactory by comparing different stages of the NYHA and the CCSFC (pMIDAS is a reliable and valid instrument.

  17. Cometary dust at the nanometre scale - the MIDAS view after perihelion

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.; Schmied, R.; Mannel, T.

    2015-10-01

    The MIDAS instrument on-board the Rosetta orbiter [1] is a unique combination of a dust collection and handling system and a high resolution Atomic Force Microscope (AFM). By building three-dimensional images of the dust particle topography with nano- to micrometre resolution, MIDAS addresses a range of fundamental questions in Solar System and cometary sciences. The greatest number of particles is expected to be collected around perihelion and the initial results of imaging these will be presented.

  18. Ionospheric tomography over South Africa: Comparison of MIDAS and ionosondes measurements

    Science.gov (United States)

    Giday, Nigussie M.; Katamzi, Zama T.; McKinnell, Lee-Anne

    2016-01-01

    This paper aims to show the results of an ionospheric tomography algorithm called Multi-Instrument Data Analysis System (MIDAS) over the South African region. Recorded data from a network of 49-53 Global Positioning System (GPS) receivers over the South African region was used as input for the inversion. The inversion was made for April, July, October and December representing the four distinct seasons (Autumn, Winter, Spring and Summer respectively) of the year 2012. MIDAS reconstructions were validated by comparing maximum electron density of the F2 layer (NmF2) and peak height (hmF2) values predicted by MIDAS to those derived from three South African ionosonde measurements. The diurnal and seasonal trends of the MIDAS NmF2 values were in good agreement with the respective NmF2 values derived from the ionosondes. In addition, good agreement was found between the two measurements with minimum and maximum coefficients of determination (r2) between 0.84 and 0.96 in all the stations and validation days. The seasonal trend of the NmF2 values over the South Africa region has been reproduced using this inversion which was in good agreement with the ionosonde measurements. Moreover, a comparison of the International Reference Ionosphere (IRI-2012) model NmF2 values with the respective ionosonde derived NmF2 values showed to have higher deviation than a similar comparison between the MIDAS reconstruction and the ionosonde measurements. However, the monthly averaged hmF2 values derived from IRI 2012 model showed better agreement than the respective MIDAS reconstructed hmF2 values compared with the ionosonde derived hmF2 values.The performance of the MIDAS reconstruction was observed to deteriorate with increased geomagnetic conditions. MIDAS reconstructed electron density were slightly elevated during three storm periods studied (24 April, 15 July and 8 October) which was in good agreement with the ionosonde measurements.

  19. Microbleed detection using automated segmentation (MIDAS): a new method applicable to standard clinical MR images.

    Science.gov (United States)

    Seghier, Mohamed L; Kolanko, Magdalena A; Leff, Alexander P; Jäger, Hans R; Gregoire, Simone M; Werring, David J

    2011-03-23

    Cerebral microbleeds, visible on gradient-recalled echo (GRE) T2* MRI, have generated increasing interest as an imaging marker of small vessel diseases, with relevance for intracerebral bleeding risk or brain dysfunction. Manual rating methods have limited reliability and are time-consuming. We developed a new method for microbleed detection using automated segmentation (MIDAS) and compared it with a validated visual rating system. In thirty consecutive stroke service patients, standard GRE T2* images were acquired and manually rated for microbleeds by a trained observer. After spatially normalizing each patient's GRE T2* images into a standard stereotaxic space, the automated microbleed detection algorithm (MIDAS) identified cerebral microbleeds by explicitly incorporating an "extra" tissue class for abnormal voxels within a unified segmentation-normalization model. The agreement between manual and automated methods was assessed using the intraclass correlation coefficient (ICC) and Kappa statistic. We found that MIDAS had generally moderate to good agreement with the manual reference method for the presence of lobar microbleeds (Kappa = 0.43, improved to 0.65 after manual exclusion of obvious artefacts). Agreement for the number of microbleeds was very good for lobar regions: (ICC = 0.71, improved to ICC = 0.87). MIDAS successfully detected all patients with multiple (≥2) lobar microbleeds. MIDAS can identify microbleeds on standard MR datasets, and with an additional rapid editing step shows good agreement with a validated visual rating system. MIDAS may be useful in screening for multiple lobar microbleeds.

  20. Aluminum (III) and gallium (III) complexes with methyliminodiacetic acid: Crystal structures of Cat[M(Mida)2] (Cat+=Na, K, NH4; M3+=Al, Ga) and Me4N[Ga(Mida)2]·H2O

    International Nuclear Information System (INIS)

    Ilyukhin, A.B.; Petrosyants, S.P.; Milovanov, S.V.; Malyarik, M.A.

    1997-01-01

    The bis chelate complexes Cat[M(Mida) 2 ] and Me 4 N[Ga(Mida) 2 ]·H 2 O are synthesized from aqueous solutions M(NO 3 ) 3 -2H 2 Mida-CatOH (M 3+ =Al, Ga; Cat + =Na, K, NH 4 ) and Ga(OH) 3 -2H 2 Mida-Me 4 NOH. The crystal structures of the isostructural compounds Cat[M(Mida) 2 ] (Cat=Na, M=Al; Cat=K, M=Al; Cat=Na, M=Ga) and Me 4 N[Ga(Mida) 2 ]·H 2 O are determined by X-ray structure analysis. According to the X-ray powder diffraction analysis, all the six compounds Cat[M(Mida) 2 ] (Cat=Na, K, NH 4 ; M=Al, Ga) are isostructural. The octahedral anion in Cat[M(Mida) 2 ] and Me 4 N[Ga(Mida) 2 ]·H 2 O exhibits a trans(N)- fac configuration

  1. Sedação com sufentanil e clonidina em pacientes submetidos a cateterismo cardíaco

    Directory of Open Access Journals (Sweden)

    Anita Perpetua Carvalho Rocha

    2011-03-01

    Full Text Available FUNDAMENTO: A sedação para a realização de cateterismo cardíaco tem sido alvo de preocupação. Benzodiazepínicos, agonistas alfa-2 adrenérgicos e opioides são utilizados para esse fim, entretanto, cada um destes medicamentos possui vantagens e desvantagens. OBJETIVO: Avaliar a eficácia do sufentanil e da clonidina como sedativos em pacientes submetidos a cateterismo cardíaco, observando o impacto dos mesmos sobre os parâmetros hemodinâmicos e respiratórios, a presença de efeitos colaterais, além da satisfação do paciente e do hemodinamicista com o exame. MÉTODOS: Trata-se de um ensaio clínico prospectivo, duplo-cego, randomizado e controlado, que envolveu 60 pacientes que receberam 0,1 µg/kg de sufentanil ou 0,5 µg/kg de clonidina antes da realização do cateterismo cardíaco. O escore de sedação segundo a escala de Ramsay, a necessidade de utilização de midazolam, os efeitos colaterais, os parâmetros hemodinâmicos e respiratórios foram registrados, sendo os dados analisados em 06 diferentes momentos. RESULTADOS: O comportamento da pressão arterial, da frequência cardíaca e da frequência respiratória foi semelhante nos dois grupos, entretanto, no momento 2, os pacientes do grupo sufentanil (Grupo S apresentaram menor escore de sedação segundo a escala de Ramsay, e a saturação periférica da oxihemoglobina foi menor que o grupo clonidina (Grupo C no momento 6. Os pacientes do Grupo S apresentaram maior incidência de náusea e vômito pós-operatório que os pacientes do Grupo C. A satisfação dos pacientes foi maior no grupo clonidina. Os hemodinamicistas mostraram-se satisfeitos nos dois grupos. CONCLUSÃO: O sufentanil e a clonidina foram efetivos como sedativos em pacientes submetidos a cateterismo cardíaco.

  2. Measurement result of the neutron monitor onboard the Space Environment Data Acquisition Equipment - Attached Payload (SEDA-AP)

    Science.gov (United States)

    Koga, K.; Muraki, Y.; Shibata, S.; Yamamoto, T.; Matsumoto, H.; Okudaira, O.; Kawano, H.; Yumoto, K.

    2013-12-01

    To support future space activities, it is crucial to acquire space environmental data related to the space-radiation degradation of space parts and materials, and spacecraft anomalies. Such data are useful for spacecraft design and manned space activity. SEDA-AP was mounted on 'Kibo' of the ISS (International Space Station) to measure the space environment at a 400-kilometer altitude. Neutrons are very harmful radiation, with electrical neutrality that makes them strongly permeable. SEDA-AP measures the energy of neutrons from thermal to 100 MeV in real time using a Bonner Ball Detector (BBND) and a Scintillation Fiber Detector (FIB). BBND detects neutrons using He-3 counters, which have high sensitivity to thermal neutrons. Neutron energy is derived using the relative response function of polyethylene moderators of 6 different thicknesses. FIB measures the tracks of recoil protons caused by neutrons within a cubic arrayed sensor of 512 scintillation fibers. The charged particles are excluded using an anti-scintillator which surrounds the cube sensor, and the neutron energy is obtained from the track length of a recoil proton. There are three sources of neutrons in space; 1. Albedo Neutrons Produced by reactions of galactic cosmic rays or radiation belt particles with the atmosphere 2. Local Neutrons Produced by the reactions of galactic cosmic rays or radiation belt particles with spacecraft 3. Solar Neutrons Produced by accelerated particles in solar flares An accurate energy spectrum of the solar neutrons includes important information on high-energy particle generation mechanism in a solar flare, because neutrons are unaffected by interplanetary magnetic fields. These data will become useful to forecast solar energetic particles in future. Some candidate events involving solar neutrons were found as a result of analyzing data of the solar flare of M>2 since September 2009. Moreover, it is important to measure albedo neutrons, since protons generated by neutron

  3. Sedação com propofol e alfentanil para litotripsia extracorpórea por ondas de choque

    Directory of Open Access Journals (Sweden)

    José Roberto Nociti

    2002-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Este estudo não-comparativo tem por objetivo pesquisar as doses adequadas de propofol e alfentanil em sedação para litotripsia extracorpórea por ondas de choque (LEOC bem como o tempo necessário para a alta hospitalar. MÉTODO: Foram observados 24 pacientes consecutivos de ambos os sexos submetidos a LEOC em regime ambulatorial, com estado físico ASA I ou II, sob sedação por via venosa com propofol na dose inicial de 1 mg.kg-1, seguida de infusão contínua com velocidade variável, e alfentanil na dose inicial de 15 µg.kg-1, seguida de bolus adicionais de 5 µg.kg-1 conforme as necessidades clínicas. Monitorização de SpO2, PAS, PAD e FC por método não-invasivo e alta hospitalar conforme critérios propostos por Kortilla para pacientes ambulatoriais. RESULTADOS: A duração média dos procedimentos foi de 46,8 ± 12,8 minutos. As doses totais médias de propofol e de alfentanil foram respectivamente de 59,0 ± 17,9 µg.kg-1.min-1 e 0,38 ± 0,14 µg.kg-1.min-1. Alta hospitalar em até 60 minutos em 58,3% dos casos; de 61 a 90 minutos em 20,9%; de 91 a 120 minutos em 12,5%; e acima de 120 minutos em 8,3%. Ocorreu dessaturação do sangue arterial (SpO2 £ 85% em pelo menos uma ocasião em 45,8% dos pacientes, com rápida recuperação após fornecimento de oxigênio a 100%. CONCLUSÕES: A sedação com propofol e alfentanil nas doses relatadas para LEOC constitui método prático, efetivo e seguro desde que adotadas medidas para monitorização e atendimento a complicações cardiorrespiratórias que podem ocorrer no curso do procedimento.

  4. El complejo manufacturero de la Real Fábrica de Sedas de Talavera de la Reina (1785

    Directory of Open Access Journals (Sweden)

    Luis Francisco Peñalver Ramos

    1996-01-01

    Full Text Available La «Real Fábrica de Tejidos de Seda, Plata y Oro» de Talavera de la Reina se fundó a mediados del siglo xviii bajo los auspicios del rey Fernando VI y teniendo como promotor principal a su Secretario de Estado, José de Carvajal y Lancaster. Su creación constituye un exponente más de la política económica de los Borbones españoles, iniciada por Felipe V tras la Guerra de Sucesión mediante un programa de reformas económicas con el fin de alcanzar una balanza comercial favorable para nuestra nación, y evitar de esta forma la dependencia del exterior, especialmente de Francia e Inglaterra. Para lograr llevar a cabo este proyecto era necesario una puesta al día de la industria, y entre otros sectores, del textil.

  5. Content Validity and Reliability of Multiple Intelligences Developmental Assessment Scales (MIDAS Translated into Persian

    Directory of Open Access Journals (Sweden)

    Mahnaz Saeidi

    2012-11-01

    Full Text Available This study aimed to translate MIDAS questionnaire from English into Persian and determine its content validity and reliability. MIDAS was translated and validated on a sample (N = 110 of Iranian adult population. The participants were both male and female with the age range of 17-57. They were at different educational levels and from different ethnic groups in Iran. A translating team, consisting of five members, bilingual in English and Persian and familiar with multiple intelligences (MI theory and practice, were involved in translating and determining content validity, which included the processes of forward translation, back-translation, review, final proof-reading, and testing. The statistical analyses of inter-scale correlation were performed using the Cronbach's alpha coefficient. In an intra-class correlation, the Cronbach's alpha was high for all of the questions. Translation and content validity of MIDAS questionnaire was completed by a proper process leading to high reliability and validity. The results suggest that Persian MIDAS (P-MIDAS could serve as a valid and reliable instrument for measuring Iranian adults MIs.

  6. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez-Muñiz, J. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Amaral Soares, E. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Berlin, A.; Bogdan, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Boháčová, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Institute of Physics of the Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-182 21 Praha 8 (Czech Republic); Bonifazi, C. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Carvalho, W.R. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Mello Neto, J.R.T. de [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Facal San Luis, P., E-mail: facal@kicp.uchicago.edu [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); and others

    2013-08-11

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique.

  7. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    International Nuclear Information System (INIS)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Facal San Luis, P.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.

    2013-01-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique

  8. Polarized light use in the nocturnal bull ant, Myrmecia midas.

    Science.gov (United States)

    Freas, Cody A; Narendra, Ajay; Lemesle, Corentin; Cheng, Ken

    2017-08-01

    Solitary foraging ants have a navigational toolkit, which includes the use of both terrestrial and celestial visual cues, allowing individuals to successfully pilot between food sources and their nest. One such celestial cue is the polarization pattern in the overhead sky. Here, we explore the use of polarized light during outbound and inbound journeys and with different home vectors in the nocturnal bull ant, Myrmecia midas . We tested foragers on both portions of the foraging trip by rotating the overhead polarization pattern by ±45°. Both outbound and inbound foragers responded to the polarized light change, but the extent to which they responded to the rotation varied. Outbound ants, both close to and further from the nest, compensated for the change in the overhead e-vector by about half of the manipulation, suggesting that outbound ants choose a compromise heading between the celestial and terrestrial compass cues. However, ants returning home compensated for the change in the e-vector by about half of the manipulation when the remaining home vector was short (1-2 m) and by more than half of the manipulation when the remaining vector was long (more than 4 m). We report these findings and discuss why weighting on polarization cues change in different contexts.

  9. A restructuring of TF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2002-01-01

    TF package which defines some interpolation and extrapolation condition through user defined table has been restructured in MIDAS computer code. To do this, data transferring methods of current MELCOR code are modified and adopted into TF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of TF package addressed in this paper does module development and subroutine modification, and treats MELGEN which is making restart file as well as MELCOR which is processing calculation. The validation has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. It hints that the similar approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  10. Topografia do cone medular do sauim (Saguinus midas Topography of the medullary cone in sauim (Saguinus midas

    Directory of Open Access Journals (Sweden)

    Danielli Martinelli Martins

    2013-06-01

    Full Text Available Primata endêmico do Brasil, especificamente da floresta Amazônica, o Sauim alimentam-se de pequenos vertebrados, invertebrados, exudatos, flores, néctar, folhas e fungos, cuja morfologia é pouco conhecida. Assim, objetivou-se estabelecer parâmetros morfométricos e topográficos do cone medular dessa espécie, que sirvam de base para a prática das anestesias epidurais. Para tanto, foram avaliados quatro exemplares, provenientes da Universidade Federal Rural da Amazônia (UFRA. O Saguinus midas apresentou sete vértebras lombares e três vértebras sacrais. Após a dissecação do cone medular, registrou-se os aspectos anatômicos de interesse, enfatizando seu início (base e seu término (ápice, que, após mensuração, revelou base em nível de L4 e ápice em S2, com comprimento médio de 5,38cm, o que leva a sugerir a região lombosacral como sendo a mais adequada para o desenvolvimento da prática de anestesias epidurais.Primate endemic to Brazil, specifically in the Amazon rainforest, the Sauim feed on small vertebrates, invertebrates, exudates, flowers, nectar, leaves and fungi whose morphology is poorly known. Thus, the objective was to establish morphometric parameters and topographical conus of this species, as a basis for the practice of epidural anesthesia. For this purpose, four samples were evaluated, from the Universidade Federal Rural da Amazônia (UFRA. The Saguinus midas had seven lumbar vertebrae and three sacral vertebrae. After dissection of the conus, we recorded the anatomy of interest, emphasizing its beginning (base and its end (apex, revealed that after measuring the level of base peak in L4 and S2, with an average length of 5.38cm, which leads us to suggest the lumbosacral region as the most suitable for the development of the practice of epidural anesthesia.

  11. A Multi-Cultural Comparison of the Factor Structure of the MIDAS for Adults/College Students.

    Science.gov (United States)

    Jones, James A.

    The Multiple Intelligences Developmental Assessment Scales (MIDAS) instrument was developed to measure eight constructs of intelligence. The 119-item MIDAS provides scores for 26 subscales in addition to the 8 major scales. Using the 26 subscales, a factor structure was developed on half of a U.S. sample of college students (n=834), while the…

  12. MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

    DEFF Research Database (Denmark)

    Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

    this information in MiDAS field guide (www.midasfieldguide.org). MiDAS taxonomy gives a solid foundation for the study of microbial ecology of the wastewater treatment processes. The online MiDAS field guide links the identity of genera that are important for the wastewater treatment process to details about...... guide to the microbes of activated sludge by comparing microbial community composition in 32 WWTPs located worldwide. This will facilitate a better understanding of the ecology of the ecosystem of activated sludge. Reference: McIlroy et al. MiDAS: the field guide to the microbes of activated sludge...... on a survey of 25 full-scale Danish wastewater treatment plants over 6 years and using MiDAS taxonomy, we have collected more than 150 key organisms in activated sludge wastewater treatment systems, linked their identity with available information on their function and distribution and included...

  13. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Science.gov (United States)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W. R.; de Mello Neto, J. R. T.; Facal San Luis, P.; Genat, J. F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.; Ramos de Castro, A.; Reyes, L. C.; Richardson, M.; Rouille d'Orfeuil, B.; Santos, E. M.; Wayne, S.; Williams, C.; Zas, E.; Zhou, J.

    2013-08-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4-4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope - to validate the telescope design, and to demonstrate a large detector duty cycle - were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory.

  14. Simulation of the condensation experiment for the SG primary of SMART with MIDAS/SMR

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cho, Seong Won [Korea Radiation Technology Institute Co., Daejeon (Korea, Republic of)

    2012-05-15

    SMART is new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. MIDAS/SMR V1.0.3 code has been used for estimating the severe accident from SMART. SMART has the SG tube with helical shape that is different from that of PWR. MIDAS code has the condensation model for the both sides of surfaces from the various kinds of geometry. But it does not have the condensation model for the helical type of tube. In this study, the condensation experiment for the outer surface of the SG tube in SMART that was performed by Po-Hang university was simulated with MIDAS/SMR under the assumption of straight pipe. The simulation results showed well predictions of the amount of heat removal from the SG tube primary side and thermal hydraulic parameters

  15. The Virtual Midas Touch: Helping Behavior After a Mediated Social Touch.

    Science.gov (United States)

    Haans, A; Usselsteijn, W A

    2009-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply with a request. In this paper, we investigate whether this Midas touch phenomenon would also occur under mediated conditions (i.e., touching via an arm strap equipped with electromechanical actuators). Helping behavior was more frequently endorsed in the touch, compared to the no-touch condition, but this difference was not found to be statistically significant. However, a meta-analytical comparison with published research demonstrated that the strength of the virtual Midas touch is of the same magnitude as that of the Midas touch in unmediated situations. The present experiment, thus, provides empirical evidence that touch-like qualities can be attributed to electromechanical stimulation. This is important for the field of mediated social touch of which the design rationale is based on the assumption that mediated touch by means of tactile feedback technologies is processed in ways similar to real physical contact.

  16. Simulation of the condensation experiment for the SG primary of SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2012-01-01

    SMART is new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. MIDAS/SMR V1.0.3 code has been used for estimating the severe accident from SMART. SMART has the SG tube with helical shape that is different from that of PWR. MIDAS code has the condensation model for the both sides of surfaces from the various kinds of geometry. But it does not have the condensation model for the helical type of tube. In this study, the condensation experiment for the outer surface of the SG tube in SMART that was performed by Po-Hang university was simulated with MIDAS/SMR under the assumption of straight pipe. The simulation results showed well predictions of the amount of heat removal from the SG tube primary side and thermal hydraulic parameters

  17. MIDAS, prototype Multivariate Interactive Digital Analysis System, phase 1. Volume 3: Wiring diagrams

    Science.gov (United States)

    Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.

    1974-01-01

    The Midas System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughput. The hardware and software generated in Phase I of the overall program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 2 x 100,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. The MIDAS construction and wiring diagrams are given.

  18. MIDAS, prototype Multivariate Interactive Digital Analysis System, Phase 1. Volume 2: Diagnostic system

    Science.gov (United States)

    Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.

    1974-01-01

    The MIDAS System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughout. The hardware and software generated in Phase I of the over-all program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating 2 x 105 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. Diagnostic programs used to test MIDAS' operations are presented.

  19. Rapid and Parallel Adaptive Evolution of the Visual System of Neotropical Midas Cichlid Fishes.

    Science.gov (United States)

    Torres-Dowdall, Julián; Pierotti, Michele E R; Härer, Andreas; Karagic, Nidal; Woltering, Joost M; Henning, Frederico; Elmer, Kathryn R; Meyer, Axel

    2017-10-01

    Midas cichlid fish are a Central American species flock containing 13 described species that has been dated to only a few thousand years old, a historical timescale infrequently associated with speciation. Their radiation involved the colonization of several clear water crater lakes from two turbid great lakes. Therefore, Midas cichlids have been subjected to widely varying photic conditions during their radiation. Being a primary signal relay for information from the environment to the organism, the visual system is under continuing selective pressure and a prime organ system for accumulating adaptive changes during speciation, particularly in the case of dramatic shifts in photic conditions. Here, we characterize the full visual system of Midas cichlids at organismal and genetic levels, to determine what types of adaptive changes evolved within the short time span of their radiation. We show that Midas cichlids have a diverse visual system with unexpectedly high intra- and interspecific variation in color vision sensitivity and lens transmittance. Midas cichlid populations in the clear crater lakes have convergently evolved visual sensitivities shifted toward shorter wavelengths compared with the ancestral populations from the turbid great lakes. This divergence in sensitivity is driven by changes in chromophore usage, differential opsin expression, opsin coexpression, and to a lesser degree by opsin coding sequence variation. The visual system of Midas cichlids has the evolutionary capacity to rapidly integrate multiple adaptations to changing light environments. Our data may indicate that, in early stages of divergence, changes in opsin regulation could precede changes in opsin coding sequence evolution. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. MIDAS robust trend estimator for accurate GPS station velocities without step detection

    Science.gov (United States)

    Blewitt, Geoffrey; Kreemer, Corné; Hammond, William C.; Gazeaux, Julien

    2016-03-01

    Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and heteroscedasticity. Developed here, Median Interannual Difference Adjusted for Skewness (MIDAS) is a variant of the Theil-Sen median trend estimator, for which the ordinary version is the median of slopes vij = (xj-xi)/(tj-ti) computed between all data pairs i > j. For normally distributed data, Theil-Sen and least squares trend estimates are statistically identical, but unlike least squares, Theil-Sen is resistant to undetected data problems. To mitigate both seasonality and step discontinuities, MIDAS selects data pairs separated by 1 year. This condition is relaxed for time series with gaps so that all data are used. Slopes from data pairs spanning a step function produce one-sided outliers that can bias the median. To reduce bias, MIDAS removes outliers and recomputes the median. MIDAS also computes a robust and realistic estimate of trend uncertainty. Statistical tests using GPS data in the rigid North American plate interior show ±0.23 mm/yr root-mean-square (RMS) accuracy in horizontal velocity. In blind tests using synthetic data, MIDAS velocities have an RMS accuracy of ±0.33 mm/yr horizontal, ±1.1 mm/yr up, with a 5th percentile range smaller than all 20 automatic estimators tested. Considering its general nature, MIDAS has the potential for broader application in the geosciences.

  1. A preliminary psychometric evaluation of Music in Dementia Assessment Scales (MiDAS)

    DEFF Research Database (Denmark)

    McDermott, Orii; Orgeta, Vasiliki; Ridder, Hanne Mette Ochsner

    2014-01-01

    despite the small sample size. Future research with a larger sample size could provide a more in-depth psychometric evaluation, including further exploration of the underlying factors. MiDAS provides a measure of engagement with musical experience and offers insight into who is likely to benefit on other......Background: Music in Dementia Assessment Scales (MiDAS), an observational outcome measure for music therapy with people with moderate to severe dementia, was developed from qualitative data of focus groups and interviews. Expert and peer consultations were conducted at each stage of the scale...

  2. Importance of the macroeconomic variables for variance prediction: A GARCH-MIDAS approach

    DEFF Research Database (Denmark)

    Asgharian, Hossein; Hou, Ai Jun; Javed, Farrukh

    2013-01-01

    This paper aims to examine the role of macroeconomic variables in forecasting the return volatility of the US stock market. We apply the GARCH-MIDAS (Mixed Data Sampling) model to examine whether information contained in macroeconomic variables can help to predict short-term and long-term compone......This paper aims to examine the role of macroeconomic variables in forecasting the return volatility of the US stock market. We apply the GARCH-MIDAS (Mixed Data Sampling) model to examine whether information contained in macroeconomic variables can help to predict short-term and long...

  3. How MIDAS improved our understanding of micrometre-sized cometary dust

    Science.gov (United States)

    Mannel, T.; Bentley, M. S.; Boakes, P.; Jeszenszky, H.; Levasseur-Regourd, A. C.; Schmied, R.; Torkar, K.

    2017-09-01

    The MIDAS atomic force microscope on the Rosetta orbiter was an instrument developed to investigate, for the first time, the morphology of nearly unaltered cometary dust. It acquired the 3D topography of about 1 - 50 µm sized dust particles with resolutions down to a few nanometres. These images showed the agglomerate character of the dust and confirmed that the smallest subunit sizes were less than 100 nm. MIDAS acquired the first direct proof of a fractal dust particle, opening a new approach to investigate the history of our early Solar System and of comets.

  4. Simulation of the VISTA SG heat transfer experiment using MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2011-01-01

    As the SMART plant was designed with the helical type tubes in the steam generators, the heat transfer model in that geometry has been implemented in the TASS/SMR-S code and used for the safety analysis. The same correlation was implemented in the MIDAS/SMR, which is being used for the severe accident analyses, to model heat transfer at the steam generators. In this study, the VISTA SG experiment with the helical steam generator tube was simulated with MIDAS/SMR to compare the heat transfer rates through the helical tube

  5. Translation, cross-cultural adaptation and reliability of the German version of the migraine disability assessment (MIDAS) questionnaire.

    Science.gov (United States)

    Benz, Thomas; Lehmann, Susanne; Gantenbein, Andreas R; Sandor, Peter S; Stewart, Walter F; Elfering, Achim; Aeschlimann, André G; Angst, Felix

    2018-03-09

    The Migraine Disability Assessment (MIDAS) is a brief questionnaire and measures headache-related disability. This study aimed to translate and cross-culturally adapt the original English version of the MIDAS to German and to test its reliability. The standardized translation process followed international guidelines. The pre-final version was tested for clarity and comprehensibility by 34 headache sufferers. Test-retest reliability of the final version was quantified by 36 headache patients completing the MIDAS twice with an interval of 48 h. Reliability was determined by intraclass correlation coefficients and internal consistency by Cronbach's α. All steps of the translation process were followed, documented and approved by the developer of the MIDAS. The expert committee discussed in detail the complex phrasing of the questions that refer to one to another, especially exclusion of headache-days from one item to the next. The German version contains more active verb sentences and prefers the perfect to the imperfect tense. The MIDAS scales intraclass correlation coefficients ranged from 0.884 to 0.994 and was 0.991 (95% CI: 0.982-0.995) for the MIDAS total score. Cronbach's α for the MIDAS as a whole was 0.69 at test and 0.67 at retest. The translation process was challenged by the comprehensibility of the questionnaire. The German version of the MIDAS is a highly reliable instrument for assessing headache related disability with moderate internal consistency. Provided validity testing of the German MIDAS is successful, it can be recommended for use in clinical practice as well as in research.

  6. Man-Machine Integrated Design and Analysis System (MIDAS): Functional Overview

    Science.gov (United States)

    Corker, Kevin; Neukom, Christian

    1998-01-01

    Included in the series of screen print-outs illustrates the structure and function of the Man-Machine Integrated Design and Analysis System (MIDAS). Views into the use of the system and editors are featured. The use-case in this set of graphs includes the development of a simulation scenario.

  7. [Mida väärtustada ja arendada koolis...] / Maria Tiro

    Index Scriptorium Estoniae

    Tiro, Maria

    2009-01-01

    Mida väärtustada ja arendada koolis ajal, mil Eesti paljudes paikades õpilaste arv väheneb ning inimesed koonduvad linnade ümbrusesse? Rae valla näite põhjal Jüri Gümnaasiumi direktor Maria Tiro

  8. Default probabilities, CDS premiums and downgrades : A probit-MIDAS analysis

    NARCIS (Netherlands)

    Freitag, L.

    2014-01-01

    This paper examines the relationship between sovereign credit default swaps (CDS) and sovereign rating changes of European countries. To this aim, a new estimator is introduced which merges mixed data sampling (MIDAS) with probit regression. Simulations show that the estimator has good properties in

  9. Sensitivity analysis of MIDAS tests using SPACE code. Effect of nodalization

    International Nuclear Information System (INIS)

    Eom, Shin; Oh, Seung-Jong; Diab, Aya

    2018-01-01

    The nodalization sensitivity analysis for the ECCS (Emergency Core Cooling System) bypass phe�nomena was performed using the SPACE (Safety and Performance Analysis CodE) thermal hydraulic analysis computer code. The results of MIDAS (Multi-�dimensional Investigation in Downcomer Annulus Simulation) test were used. The MIDAS test was conducted by the KAERI (Korea Atomic Energy Research Institute) for the performance evaluation of the ECC (Emergency Core Cooling) bypass phenomenon in the DVI (Direct Vessel Injection) system. The main aim of this study is to examine the sensitivity of the SPACE code results to the number of thermal hydraulic channels used to model the annulus region in the MIDAS experiment. The numerical model involves three nodalization cases (4, 6, and 12 channels) and the result show that the effect of nodalization on the bypass fraction for the high steam flow rate MIDAS tests is minimal. For computational efficiency, a 4 channel representation is recommended for the SPACE code nodalization. For the low steam flow rate tests, the SPACE code over-�predicts the bypass fraction irrespective of the nodalization finesse. The over-�prediction at low steam flow may be attributed to the difficulty to accurately represent the flow regime in the vicinity of the broken cold leg.

  10. A virtual Midas touch? : touch, compliance, and confederate bias in mediated communication

    NARCIS (Netherlands)

    Haans, A.; Bruijn, de R.; IJsselsteijn, W.A.

    2014-01-01

    A brief touch to the shoulder or upper arm increases people’s helping behavior and willingness to comply with requests. In this manuscript, we investigate whether this well-known Midas touch effect is also operative in mediated interactions where the touch act is replaced by electromechanical

  11. The virtual midas touch : helping behavior after a mediated social touch

    NARCIS (Netherlands)

    Haans, A.; IJsselsteijn, W.A.

    2009-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply with a request. In this paper, we investigate whether this Midas touch phenomenon would also occur under mediated conditions (i.e., touching via an arm strap equipped with electromechanical actuators).

  12. MIDAS: a practical Bayesian design for platform trials with molecularly targeted agents.

    Science.gov (United States)

    Yuan, Ying; Guo, Beibei; Munsell, Mark; Lu, Karen; Jazaeri, Amir

    2016-09-30

    Recent success of immunotherapy and other targeted therapies in cancer treatment has led to an unprecedented surge in the number of novel therapeutic agents that need to be evaluated in clinical trials. Traditional phase II clinical trial designs were developed for evaluating one candidate treatment at a time and thus not efficient for this task. We propose a Bayesian phase II platform design, the multi-candidate iterative design with adaptive selection (MIDAS), which allows investigators to continuously screen a large number of candidate agents in an efficient and seamless fashion. MIDAS consists of one control arm, which contains a standard therapy as the control, and several experimental arms, which contain the experimental agents. Patients are adaptively randomized to the control and experimental agents based on their estimated efficacy. During the trial, we adaptively drop inefficacious or overly toxic agents and 'graduate' the promising agents from the trial to the next stage of development. Whenever an experimental agent graduates or is dropped, the corresponding arm opens immediately for testing the next available new agent. Simulation studies show that MIDAS substantially outperforms the conventional approach. The proposed design yields a significantly higher probability for identifying the promising agents and dropping the futile agents. In addition, MIDAS requires only one master protocol, which streamlines trial conduct and substantially decreases the overhead burden. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  13. The virtual Midas touch : helping behavior after a mediated social touch

    NARCIS (Netherlands)

    Haans, A.; IJsselsteijn, W.A.; Graus, M.P.; Salminen, J.A.

    2008-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply to a request. In this paper, we investigate whether this Midas Touch effect would also occur under mediated conditions (i.e., a text messaging system and an arm strap equipped with vibrotactile

  14. MiDAS: the field guide to the microbes of activated sludge.

    Science.gov (United States)

    McIlroy, Simon Jon; Saunders, Aaron Marc; Albertsen, Mads; Nierychlo, Marta; McIlroy, Bianca; Hansen, Aviaja Anna; Karst, Søren Michael; Nielsen, Jeppe Lund; Nielsen, Per Halkjær

    2015-01-01

    The Microbial Database for Activated Sludge (MiDAS) field guide is a freely available online resource linking the identity of abundant and process critical microorganisms in activated sludge wastewater treatment systems to available data related to their functional importance. Phenotypic properties of some of these genera are described, but most are known only from sequence data. The MiDAS taxonomy is a manual curation of the SILVA taxonomy that proposes a name for all genus-level taxa observed to be abundant by large-scale 16 S rRNA gene amplicon sequencing of full-scale activated sludge communities. The taxonomy can be used to classify unknown sequences, and the online MiDAS field guide links the identity to the available information about their morphology, diversity, physiology and distribution. The use of a common taxonomy across the field will provide a solid foundation for the study of microbial ecology of the activated sludge process and related treatment processes. The online MiDAS field guide is a collaborative workspace intended to facilitate a better understanding of the ecology of activated sludge and related treatment processes--knowledge that will be an invaluable resource for the optimal design and operation of these systems. © The Author(s) 2015. Published by Oxford University Press.

  15. Sensitivity analysis of MIDAS tests using SPACE code. Effect of nodalization

    Energy Technology Data Exchange (ETDEWEB)

    Eom, Shin; Oh, Seung-Jong; Diab, Aya [KEPCO International Nuclear Graduate School (KINGS), Ulsan (Korea, Republic of). Dept. of NPP Engineering

    2018-02-15

    The nodalization sensitivity analysis for the ECCS (Emergency Core Cooling System) bypass phe�nomena was performed using the SPACE (Safety and Performance Analysis CodE) thermal hydraulic analysis computer code. The results of MIDAS (Multi-�dimensional Investigation in Downcomer Annulus Simulation) test were used. The MIDAS test was conducted by the KAERI (Korea Atomic Energy Research Institute) for the performance evaluation of the ECC (Emergency Core Cooling) bypass phenomenon in the DVI (Direct Vessel Injection) system. The main aim of this study is to examine the sensitivity of the SPACE code results to the number of thermal hydraulic channels used to model the annulus region in the MIDAS experiment. The numerical model involves three nodalization cases (4, 6, and 12 channels) and the result show that the effect of nodalization on the bypass fraction for the high steam flow rate MIDAS tests is minimal. For computational efficiency, a 4 channel representation is recommended for the SPACE code nodalization. For the low steam flow rate tests, the SPACE code over-�predicts the bypass fraction irrespective of the nodalization finesse. The over-�prediction at low steam flow may be attributed to the difficulty to accurately represent the flow regime in the vicinity of the broken cold leg.

  16. Adaptive phenotypic plasticity in the Midas cichlid fish pharyngeal jaw and its relevance in adaptive radiation

    Directory of Open Access Journals (Sweden)

    Salzburger Walter

    2011-04-01

    Full Text Available Abstract Background Phenotypic evolution and its role in the diversification of organisms is a central topic in evolutionary biology. A neglected factor during the modern evolutionary synthesis, adaptive phenotypic plasticity, more recently attracted the attention of many evolutionary biologists and is now recognized as an important ingredient in both population persistence and diversification. The traits and directions in which an ancestral source population displays phenotypic plasticity might partly determine the trajectories in morphospace, which are accessible for an adaptive radiation, starting from the colonization of a novel environment. In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations. The Midas Cichlid (Amphilophus spp. in Nicaragua has radiated in parallel in several crater-lakes seeded by populations originating from the Nicaraguan Great Lakes. Here, we tested phenotypic plasticity in the pharyngeal jaw of Midas Cichlids. The pharyngeal jaw apparatus of cichlids, a second set of jaws functionally decoupled from the oral ones, is known to mediate ecological specialization and often differs strongly between sister-species. Results We performed a common garden experiment raising three groups of Midas cichlids on food differing in hardness and calcium content. Analyzing the lower pharyngeal jaw-bones we find significant differences between diet groups qualitatively resembling the differences found between specialized species. Observed differences in pharyngeal jaw expression between groups were attributable to the diet's mechanical resistance, whereas surplus calcium in the diet was not found to be of importance. Conclusions The pharyngeal jaw apparatus of Midas Cichlids can be expressed plastically if stimulated mechanically during feeding. Since this trait is commonly differentiated - among

  17. Adaptive phenotypic plasticity in the Midas cichlid fish pharyngeal jaw and its relevance in adaptive radiation.

    Science.gov (United States)

    Muschick, Moritz; Barluenga, Marta; Salzburger, Walter; Meyer, Axel

    2011-04-30

    Phenotypic evolution and its role in the diversification of organisms is a central topic in evolutionary biology. A neglected factor during the modern evolutionary synthesis, adaptive phenotypic plasticity, more recently attracted the attention of many evolutionary biologists and is now recognized as an important ingredient in both population persistence and diversification. The traits and directions in which an ancestral source population displays phenotypic plasticity might partly determine the trajectories in morphospace, which are accessible for an adaptive radiation, starting from the colonization of a novel environment. In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations. The Midas Cichlid (Amphilophus spp.) in Nicaragua has radiated in parallel in several crater-lakes seeded by populations originating from the Nicaraguan Great Lakes. Here, we tested phenotypic plasticity in the pharyngeal jaw of Midas Cichlids. The pharyngeal jaw apparatus of cichlids, a second set of jaws functionally decoupled from the oral ones, is known to mediate ecological specialization and often differs strongly between sister-species. We performed a common garden experiment raising three groups of Midas cichlids on food differing in hardness and calcium content. Analyzing the lower pharyngeal jaw-bones we find significant differences between diet groups qualitatively resembling the differences found between specialized species. Observed differences in pharyngeal jaw expression between groups were attributable to the diet's mechanical resistance, whereas surplus calcium in the diet was not found to be of importance. The pharyngeal jaw apparatus of Midas Cichlids can be expressed plastically if stimulated mechanically during feeding. Since this trait is commonly differentiated--among other traits--between Midas Cichlid species, its plasticity

  18. The structure of cometary dust - first results from the MIDAS Atomic Force Microscope onboard Rosetta

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Romstedt, J.

    2014-12-01

    A decade after launch the European Space Agency's Rosetta spacecraft has finally arrived at comet 67P/Churyumov-Gerasimenko. Unlike previous cometary missions, Rosetta is not a flyby, limited to taking a snapshot of the comet at a single heliocentric distance. Instead, Rosetta intercepted the comet prior to the onset of major activity and will chart its evolution during its perihelion passage and beyond. Such a unique mission requires a unique payload; as well as the more typical remote sensing instruments, Rosetta also carries sensors to sample in situ the gas and dust environment. One of these instruments is MIDAS, an atomic force microscope designed to collect dust and image it in three dimensions with nanometre resolution. Equipped with an array of sharp tips, four of which are magnetised to allow magnetic force microscopy, MIDAS exposes targets to the incident flux after which they are moved to the microscope for analysis. As well as extending coverage of the dust size distribution down to the finest particles, MIDAS has the unique capability to determine the shape of pristine particles - to determine, for example, if they are compact or fluffy, and to look for features which may be diagnostic of their formation environment or evolution. The magnetic mode lets MIDAS probe samples for magnetic material and to map its location if present. Having been operating almost continuously after hibernation imaging empty targets before exposure, the first exposures were performed when Rosetta entered 30 km bound orbits. The first MIDAS images and analyses of collected dust grains are presented here.

  19. MIDAS: Mining differentially activated subpaths of KEGG pathways from multi-class RNA-seq data.

    Science.gov (United States)

    Lee, Sangseon; Park, Youngjune; Kim, Sun

    2017-07-15

    Pathway based analysis of high throughput transcriptome data is a widely used approach to investigate biological mechanisms. Since a pathway consists of multiple functions, the recent approach is to determine condition specific sub-pathways or subpaths. However, there are several challenges. First, few existing methods utilize explicit gene expression information from RNA-seq. More importantly, subpath activity is usually an average of statistical scores, e.g., correlations, of edges in a candidate subpath, which fails to reflect gene expression quantity information. In addition, none of existing methods can handle multiple phenotypes. To address these technical problems, we designed and implemented an algorithm, MIDAS, that determines condition specific subpaths, each of which has different activities across multiple phenotypes. MIDAS utilizes gene expression quantity information fully and the network centrality information to determine condition specific subpaths. To test performance of our tool, we used TCGA breast cancer RNA-seq gene expression profiles with five molecular subtypes. 36 differentially activate subpaths were determined. The utility of our method, MIDAS, was demonstrated in four ways. All 36 subpaths are well supported by the literature information. Subsequently, we showed that these subpaths had a good discriminant power for five cancer subtype classification and also had a prognostic power in terms of survival analysis. Finally, in a performance comparison of MIDAS to a recent subpath prediction method, PATHOME, our method identified more subpaths and much more genes that are well supported by the literature information. http://biohealth.snu.ac.kr/software/MIDAS/. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  20. Detection and localisation of the abalone probiotic Vibrio midae SY9 and its extracellular protease, VmproA, within the digestive tract of the South African abalone, Haliotis midae.

    Directory of Open Access Journals (Sweden)

    Robert J Huddy

    Full Text Available Probiotics have been widely reported to increase the growth rate of commercially important fish and shellfish by enhancing the digestion of ingested feed through the production of extracellular enzymes such as proteases and alginases. In order to investigate this further, the objective of this study was to localise the bacterial probiont Vibrio midae SY9 and one of the extracellular proteases it produces in the digestive tract of the South African abalone Haliotis midae. This was accomplished by inserting a promotorless gfp gene into the chromosome of the bacterium which was incorporated in an artificial, fishmeal-based abalone feed. In situ histological comparison of abalone fed either a basal diet or the basal diet supplemented with V. midae SY9::Tn10.52 using a cocktail of DNA probes to the gfp gene localised the probiont to the crop/stomach and intestinal regions of the H. midae digestive tract. Generally, the ingested probiotic bacterium occurred in association with feed and particulate matter within the crop/stomach and intestinal regions, as well as adhered to the wall of the crop/stomach. Histological immunohistochemical examination using polyclonal anti-VmproA antibodies localised an extracellular protease produced by V. midae SY9 to the H. midae crop/stomach and intestine where it appeared to be associated with feed and/or other particulate matter in the abalone gut. Thus the data suggests that V. midae SY9 colonises and/or adheres to the mucous lining of the abalone gut. Furthermore, the close association observed between the bacterium, its extracellular protease and ingested feed particles supports the theory that V. midae SY9 elevates in situ digestive enzyme levels and thus enhances feed digestion in farmed abalone.

  1. Detection and localisation of the abalone probiotic Vibrio midae SY9 and its extracellular protease, VmproA, within the digestive tract of the South African abalone, Haliotis midae.

    Science.gov (United States)

    Huddy, Robert J; Coyne, Vernon E

    2014-01-01

    Probiotics have been widely reported to increase the growth rate of commercially important fish and shellfish by enhancing the digestion of ingested feed through the production of extracellular enzymes such as proteases and alginases. In order to investigate this further, the objective of this study was to localise the bacterial probiont Vibrio midae SY9 and one of the extracellular proteases it produces in the digestive tract of the South African abalone Haliotis midae. This was accomplished by inserting a promotorless gfp gene into the chromosome of the bacterium which was incorporated in an artificial, fishmeal-based abalone feed. In situ histological comparison of abalone fed either a basal diet or the basal diet supplemented with V. midae SY9::Tn10.52 using a cocktail of DNA probes to the gfp gene localised the probiont to the crop/stomach and intestinal regions of the H. midae digestive tract. Generally, the ingested probiotic bacterium occurred in association with feed and particulate matter within the crop/stomach and intestinal regions, as well as adhered to the wall of the crop/stomach. Histological immunohistochemical examination using polyclonal anti-VmproA antibodies localised an extracellular protease produced by V. midae SY9 to the H. midae crop/stomach and intestine where it appeared to be associated with feed and/or other particulate matter in the abalone gut. Thus the data suggests that V. midae SY9 colonises and/or adheres to the mucous lining of the abalone gut. Furthermore, the close association observed between the bacterium, its extracellular protease and ingested feed particles supports the theory that V. midae SY9 elevates in situ digestive enzyme levels and thus enhances feed digestion in farmed abalone.

  2. Zapatero tõrjus Bushi üleskutse jääda Iraaki / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2004-01-01

    Hispaania tulevane peaminister Jose Luis Zapatero kavatseb väed Iraagist ära tuua, hoolimata USA presidendi George W. Bushi üleskutsest seda mitte teha. Avalikkuse negatiivsest arvamusest USA suhtes

  3. Las pank tuleb kiiresti kliendi juurde / Vallo Toomet

    Index Scriptorium Estoniae

    Toomet, Vallo, 1960-

    2005-01-01

    Autor on seisukohal, et pank võiks ise otsida klienti, kellele teha laenupakkumine, ning selgitab, kuidas seda ideed ellu viia. Sama süsteem võiks kehtida ka innovatsioonis, riskiprojektide puhul ja ettevõtluses

  4. Kahest halvast variandist parem / Ravil Khair Al-Din

    Index Scriptorium Estoniae

    Al-Din, Ravil Khair

    2007-01-01

    USA presidendi George W. Bushi uuest Iraagi-strateegiast ja selle kriitikast USA demokraatide poolt. Autor on seisukohal, et kui USA tahab vastutada oma seniste tegude eest Iraagis, siis saab ta seda teha vaid Iraagist lahkumata

  5. Efeito residual da jitirana, flor-de-seda e mata-pasto no cultivo da rúcula em sucessão a beterraba

    Directory of Open Access Journals (Sweden)

    Alany Moisa Bezerra Almeida

    2015-05-01

    Full Text Available O efeito residual da adubação anterior em cultivos subsequente é de suma importância, uma vez que a fertilização do solo em uma atividade tão intensa, como a olericultura, aumentaria o custo de produção sempre que fosse implantada uma nova cultura. Este trabalho foi conduzido na Fazenda Experimental Rafael Fernandes, localizada no distrito de Alagoinha, zona rural de Mossoró-RN, no período de novembro a dezembro de 2011. Objetivou-se avaliar o efeito residual da jitirana, flor-de-seda e mata-pasto no cultivo da rúcula em sucessão a beterraba. A beterraba foi plantada em parcelas de 1,2 x 1,2 m e adubado com espécies espontâneas, nas quantidades: 0,6; 1,2; 1,8; 2,4 e 3,0 kg m-2 de canteiro. Após a retirada da beterraba, semearam-se sementes de rúcula nas parcelas referente aos tratamentos acima citados. O delineamento experimental foi em blocos casualizados com três repetições, no esquema fatorial 5 x 3, sendo cinco quantidades e três tipos de adubos verdes (jitirana; flor-de-seda e mata-pasto. A cultivar de rúcula plantada foi a Cultivada. As características avaliadas foram: altura e número de folhas por planta, massa fresca, número de molho de rúcula e massa seca. Houve interação dos fatores estudados para massa fresca de rúcula e número de molhos. O efeito residual na quantidade de 3,0 kg m-2 de canteiro contribuiu para a massa fresca de rúcula da ordem de 762; 684 e 713 g m-2 de canteiro, equivalente a 6,0; 5,0 e 5,0 molhos de rúcula para jitirana, flor-de-seda e mata-pasto, respectivamente. Jitirana, flor-de-seda e mata-pasto são espécies promissoras para ser utilizadas como adubo verde na produção de hortaliças.

  6. Comparison of validity and reliability of the Migraine disability assessment (MIDAS) versus headache impact test (HIT) in an Iranian population.

    Science.gov (United States)

    Ghorbani, Abbas; Chitsaz, Ahmad

    2011-01-01

    Migraine is one of the most common headaches that affect 11% or more adult population. Recently, researchers have designed two questionnaires, namely Headache Impact Test (HIT) and Migraine Disability Assessment (MIDAS), with the aim of improving migraine care. These two tests provide a standard measurement about migraine's effects on people's life style that divide patients into 4 groups (grades) based on headaches intensity. The aim of this study was to compare the validity and reliability of these two tests. This study was designed as a multicenter, descriptive study to compare validity and reliability of Persian version of MIDAS and HIT questionnaires in 240 males and females with a migraine diagnosis according to criteria for headache and facial pain of the International Headache Society (IHS). The patients were enrolled in the study from 3 neurology clinics in Isfahan, Iran, between July 2004 and January 2005 and were evaluated at baseline (visit 1) and 4 weeks later (visit 2). According to our study, there was a high correlation between two tests (r = 0.94). This decreased their MIDAS grade in comparison to their grade HIT questionnaire. These findings demonstrated that Persian version of HIT have the same validity and reliability as MIDAS. Replying to HIT questionnaire was easier than MIDAS for Iranian patients. Physicians can reliably use the Persian translation of both MIDAS and HIT questionnaires to define the severity of illness and its treatment strategy as a self-administered report by migraine patients. However, we recommend HIT for its simplicity in headache clinics.

  7. Dansk oversættelse af MiDAS, et redskab til assessment af musikterapi for personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Lykkegaard, Chris; McDermott, Orii

    2018-01-01

    DAS explored which procedures is used for outcome measure translation and cultural adaptation, and based on this recommended a ten-step procedure. We applied this procedure in order to translate MiDAS and hereby develop the Danish MiDAS-DK. The Danish MiDAS version has been tested by more than 20 professionals......) musikterapeuten umiddelbart efter sessionen for at vurdere forandringer i selve sessionen. Der har været stor interesse for at anvende MiDAS i flere Europæiske lande, herunder Danmark. Derfor undersøgte udviklerne af MiDAS hvilke procedurer der anvendes til oversættelse og kulturel tilpasning af...... assessmentredskaber, og anbefalede på den baggrund en ti-trins procedure. Vi anvendte denne procedure til oversættelsen af MiDAS og således udviklingen af den danske MiDAS-DK. Den danske version af MiDAS er afprøvet af mere end 20 fagpersoner på baggrund af 296 udfyldte MiDAS-skemaer. Målet med artiklen er...

  8. MIDAS, prototype Multivariate Interactive Digital Analysis System, phase 1. Volume 1: System description

    Science.gov (United States)

    Kriegler, F. J.

    1974-01-01

    The MIDAS System is described as a third-generation fast multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turnaround time and significant gains in throughput. The hardware and software are described. The system contains a mini-computer to control the various high-speed processing elements in the data path, and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 200,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation.

  9. MIDAS and HIT-6 French translation: reliability and correlation between tests.

    Science.gov (United States)

    Magnoux, E; Freeman, M A; Zlotnik, G

    2008-01-01

    The aim was to evaluate the test-retest reliability of the French translation of the Migraine Disability Assessment (MIDAS) and Headache Impact Test (HIT)-6 questionnaires as applied to episodic and chronic headaches and to assess the correlation between these two questionnaires. The MIDAS and HIT-6 questionnaires, which assess the degree of migraine-related functional disability, are widely used in headache treatment clinics. The French translation has not been checked for test-retest reliability. MIDAS involves recall, over the previous 3 months, of the number of days with functional disability with regard to work and to home and social life. HIT-6 involves a more subjective and general assessment of headache-related disability over the previous 4 weeks. We expect that there may be greater impact recall bias for chronic headaches than for episodic headaches and considered it important to be able to determine if the reliability of these questionnaires is equally good for these two patient populations. Given that both questionnaires have the same objective, that of assessing headache impact, it was thought useful to determine if their results might show a correlation and if they could thus be used interchangeably. The study was approved by an external ethics committee. The subjects were patients who regularly visit the Clinique de la Migraine de Montréal, which specializes in the treatment of headaches. The MIDAS and HIT-6 questionnaires were completed by the patients during their regular visit. Twelve days later, the same questionnaires were mailed with a prepaid return envelope. Sixty-five patients were required in both the episodic and chronic headache groups, assuming an 80% questionnaire return rate. One hundred and eighty-five patients were enrolled, and 143 completed the study, 75 with episodic headaches and 68 with chronic headaches. The questionnaire return rate was 78.9%. On average, questionnaires were completed a second time 21 days after the first

  10. MIDAS - an atomic force microscope for in-situ imaging of cometary dust particles

    International Nuclear Information System (INIS)

    Fehringer, H.M.; Ruedenauer, F.G.; Steiger, W.

    1997-02-01

    Comets are interesting bodies, since they are considered to consist of matter remaining in essentially unchanged chemistry from the presolar nebula. Investigation of cometary matter therefore permits to draw conclusion s with respect to the composition of presolar matter. The atomic force microscope MIDAS will be the first instrument to analyze, within ESA's ROSETTA-mission priestine cometary matter in the form of dust particles emitted by comet WIRTANEN during its perihelion in 2013. Within this project, a dust model has been developed, permitting estimation of dust collection times required for statistically significant imaging of cometary particles. The dynamics of dust collection has been developed and experimental dust collection surfaces have been produced making use of modem nanostructuring techniques. Mechanical properties of 3-dimensional piezo-control elements, which are an essential part of the MIDAS microscope, have been determined. (author)

  11. MIDAS: Software for the detection and analysis of lunar impact flashes

    Science.gov (United States)

    Madiedo, José M.; Ortiz, José L.; Morales, Nicolás; Cabrera-Caño, Jesús

    2015-06-01

    Since 2009 we are running a project to identify flashes produced by the impact of meteoroids on the surface of the Moon. For this purpose we are employing small telescopes and high-sensitivity CCD video cameras. To automatically identify these events a software package called MIDAS was developed and tested. This package can also perform the photometric analysis of these flashes and estimate the value of the luminous efficiency. Besides, we have implemented in MIDAS a new method to establish which is the likely source of the meteoroids (known meteoroid stream or sporadic background). The main features of this computer program are analyzed here, and some examples of lunar impact events are presented.

  12. Anterior segment developmental anomalies in a 33-week-old fetus with MIDAS syndrome.

    Science.gov (United States)

    Herwig, Martina C; Loeffler, Karin U; Gembruch, Ulrich; Kuchelmeister, Klaus; Müller, Annette M

    2014-01-01

    We report anterior segment abnormalities in both eyes of a 33-week-old fetus endorsing the diagnosis of MIDAS (microphthalmia, dermal aplasia, and sclerocornea) syndrome. After abortion, the fetus was examined by a standard pediatric autopsy that included macroscopic and microscopic examination of both eyes. Postmortem findings included craniofacial stigmata (such as hypertelorism, a flat nose and low-set ears) and an agenesis of the corpus callosum. Array comparative genomic hybridization revealed a deletion of the short arm of the X chromosome (region Xp22.2 to p22.32). Ophthalmopathologic examination of the eyes revealed microphthalmia with anterior segment developmental anomalies, in particular sclerocornea and Peters' anomaly, respectively. General pathology findings plus the ocular findings allowed the diagnosis of MIDAS syndrome. A discussion of differential diagnoses is provided. This case report indicates that ophthalmopathologic investigation of fetal eyes can be of great value for the further classification of syndromes.

  13. Jansen-MIDAS: A multi-level photomicrograph segmentation software based on isotropic undecimated wavelets.

    Science.gov (United States)

    de Siqueira, Alexandre Fioravante; Cabrera, Flávio Camargo; Nakasuga, Wagner Massayuki; Pagamisse, Aylton; Job, Aldo Eloizo

    2018-01-01

    Image segmentation, the process of separating the elements within a picture, is frequently used for obtaining information from photomicrographs. Segmentation methods should be used with reservations, since incorrect results can mislead when interpreting regions of interest (ROI). This decreases the success rate of extra procedures. Multi-Level Starlet Segmentation (MLSS) and Multi-Level Starlet Optimal Segmentation (MLSOS) were developed to be an alternative for general segmentation tools. These methods gave rise to Jansen-MIDAS, an open-source software. A scientist can use it to obtain several segmentations of hers/his photomicrographs. It is a reliable alternative to process different types of photomicrographs: previous versions of Jansen-MIDAS were used to segment ROI in photomicrographs of two different materials, with an accuracy superior to 89%. © 2017 Wiley Periodicals, Inc.

  14. MIDAS (Migraine Disability Assessment: a valuable tool for work-site identification of migraine in workers in Brazil

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    Full Text Available CONTEXT: MIDAS was developed as a fast and efficient method for identification of migraine in need of medical evaluation and treatment. It was necessary to translate MIDAS, originally written in English, so as to apply it in Brazil and make it usable by individuals from a variety of social-economic-cultural backgrounds. OBJECTIVE: To translate and to apply MIDAS in Brazil. SETTING: Assessment of a sample of workers regularly employed by an oil refinery. SETTING: Refinaria Presidente Bernardes, Cubatão, São Paulo, Brazil. PARTICIPANTS: 404 workers of the company who correctly answered a questionnaire for the identification and evaluation of headache. When the individual considered it to be pertinent to his own needs, there was the option to answer MIDAS as well. METHODS: MIDAS, originally written in English, was translated into Brazilian Portuguese by a neurologist and by a translator specializing in medical texts. The final version of the translation was obtained when, for ten patients to whom it was applied, the text seemed clear and the results were consistent over three sessions. MAIN MEASUREMENTS: Prevalence and types of primary headaches, evaluation of MIDAS as a tool for identification of more severe cases. RESULTS: From the total of 419 questionnaires given to the employees, 404 were returned correctly completed. From these, 160 persons were identified as presenting headaches, 44 of whom considered it worthwhile answering MIDAS. Nine of these individuals who answered MIDAS were identified as severe cases of migraine due to disability caused by the condition. An interview on a later date confirmed these results. Three were cases of chronic daily headache (transformed migraine and six were cases of migraine. CONCLUSIONS: MIDAS translated to Brazilian Portuguese was a useful tool for identifying severe cases of migraine and of transformed migraine in a working environment. The workers did not consider MIDAS to be difficult to answer. Their

  15. MIDAS. An algorithm for the extraction of modal information from experimentally determined transfer functions

    International Nuclear Information System (INIS)

    Durrans, R.F.

    1978-12-01

    In order to design reactor structures to withstand the large flow and acoustic forces present it is necessary to know something of their dynamic properties. In many cases these properties cannot be predicted theoretically and it is necessary to determine them experimentally. The algorithm MIDAS (Modal Identification for the Dynamic Analysis of Structures) which has been developed at B.N.L. for extracting these structural properties from experimental data is described. (author)

  16. Construction simulation analysis of 120m continuous rigid frame bridge based on Midas Civil

    Science.gov (United States)

    Shi, Jing-xian; Ran, Zhi-hong

    2018-03-01

    In this paper, a three-dimensional finite element model of a continuous rigid frame bridge with a main span of 120m is established by the simulation and analysis of Midas Civil software. The deflection and stress of the main beam in each construction stage of continuous beam bridge are simulated and analyzed, which provides a reliable technical guarantee for the safe construction of the bridge.

  17. The nature of (sub-)micrometre cometary dust particles detected with MIDAS

    Science.gov (United States)

    Mannel, T.; Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.; Schmied, R.

    2015-10-01

    The MIDAS Atomic Force Microscope (AFM) onboard Rosetta collects dust particles and produces three-dimensional images with nano- to micrometre resolution. To date, several tens of particles have been detected, allowing determination of their properties at the smallest scale. The key features will be presented, including the particle size, their fragile character, and their morphology. These findings will be compared with the results of other Rosetta dust experiments.

  18. MIDAS phase II. A program for the modal analysis of structures

    International Nuclear Information System (INIS)

    Durrans, R.F.

    1980-10-01

    The application of Modal Analysis to the experimental characterisation of structures is described. A program MIDAS (Modal Identification for the Dynamic Analysis of Structures) has been developed at B.N.L. to perform this function and this report presents a full description of its use. The structures within the coolant circuits of nuclear reactors must be designed to withstand large flow and acoustic forces. (U.K.)

  19. Transcriptome characterization of the South African abalone Haliotis midae using sequencing-by-synthesis

    Directory of Open Access Journals (Sweden)

    Roodt-Wilding Rouvay

    2011-03-01

    Full Text Available Abstract Background Worldwide, the genus Haliotis is represented by 56 extant species and several of these are commercially cultured. Among the six abalone species found in South Africa, Haliotis midae is the only aquacultured species. Despite its economic importance, genomic sequence resources for H. midae, and for abalone in general, are still scarce. Next generation sequencing technologies provide a fast and efficient tool to generate large sequence collections that can be used to characterize the transcriptome and identify expressed genes associated with economically important traits like growth and disease resistance. Results More than 25 million short reads generated by the Illumina Genome Analyzer were de novo assembled in 22,761 contigs with an average size of 260 bp. With a stringent E-value threshold of 10-10, 3,841 contigs (16.8% had a BLAST homologous match against the Genbank non-redundant (NR protein database. Most of these sequences were annotated using the gene ontology (GO and eukaryotic orthologous groups of proteins (KOG databases and assigned to various functional categories. According to annotation results, many gene families involved in immune response were identified. Thousands of simple sequence repeats (SSR and single nucleotide polymorphisms (SNP were detected. Setting stringent parameters to ensure a high probability of amplification, 420 primer pairs in 181 contigs containing SSR loci were designed. Conclusion This data represents the most comprehensive genomic resource for the South African abalone H. midae to date. The amount of assembled sequences demonstrated the utility of the Illumina sequencing technology in the transcriptome characterization of a non-model species. It allowed the development of several markers and the identification of promising candidate genes for future studies on population and functional genomics in H. midae and in other abalone species.

  20. Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1.

    Science.gov (United States)

    Valdramidou, Dimitra; Humphries, Martin J; Mould, A Paul

    2008-11-21

    Integrin-ligand interactions are regulated in a complex manner by divalent cations, and previous studies have identified ligand-competent, stimulatory, and inhibitory cation-binding sites. In collagen-binding integrins, such as alpha2beta1, ligand recognition takes place exclusively at the alpha subunit I domain. However, activation of the alphaI domain depends on its interaction with a structurally similar domain in the beta subunit known as the I-like or betaI domain. The top face of the betaI domain contains three cation-binding sites: the metal-ion dependent adhesion site (MIDAS), the ADMIDAS (adjacent to MIDAS), and LIMBS (ligand-associated metal-binding site). The role of these sites in controlling ligand binding to the alphaI domain has yet to be elucidated. Mutation of the MIDAS or LIMBS completely blocked collagen binding to alpha2beta1; in contrast mutation of the ADMIDAS reduced ligand recognition but this effect could be overcome by the activating monoclonal antibody TS2/16. Hence, the MIDAS and LIMBS appear to be essential for the interaction between alphaI and betaI, whereas occupancy of the ADMIDAS has an allosteric effect on the conformation of betaI. An activating mutation in the alpha2 I domain partially restored ligand binding to the MIDAS and LIMBS mutants. Analysis of the effects of Ca(2+), Mg(2+), and Mn(2+) on ligand binding to these mutants showed that the MIDAS is a ligand-competent site through which Mn(2+) stimulates ligand binding, whereas the LIMBS is a stimulatory Ca(2+)-binding site, occupancy of which increases the affinity of Mg(2+) for the MIDAS.

  1. Cometary dust at the smallest scale - latest results of the MIDAS Atomic Force Microscope onboard Rosetta

    Science.gov (United States)

    Bentley, Mark; Torkar, Klaus; Jeszenszky, Harald; Romstedt, Jens; Schmied, Roland; Mannel, Thurid

    2015-04-01

    The MIDAS instrument onboard the Rosetta orbit is a unique combination of a dust collection and handling system and a high resolution Atomic Force Microscope (AFM). By building three-dimensional images of the dust particle topography, MIDAS addresses a range of fundamental questions in Solar System and cometary science. The first few months of dust collection and scanning revealed a deficit of smaller (micron and below) particles but eventually several 10 µm-class grains were discovered. In fact these were unexpectedly large and close to the limit of what is observable with MIDAS. As a result the sharp tip used by the AFM struck the particles from the side, causing particle breakage and distortion. Analyses so far suggest that the collected particles are fluffy aggregates of smaller sub-units, although determination of the size of these sub-units and high resolution re-imaging remains to be done. The latest findings will be presented here, including a description of the particles collected and the implications of these observations for cometary science and the Rosetta mission at comet 67P.

  2. Ground truth of (sub-)micrometre cometary dust - Results of MIDAS onboard Rosetta

    Science.gov (United States)

    Mannel, Thurid; Bentley, Mark; Schmied, Roland; Torkar, Klaus; Jeszenszky, Harald; Romsted, Jens; Levasseur-Regourd, A.; Weber, Iris; Jessberger, Elmar K.; Ehrenfreund, Pascale; Köberl, Christian; Havnes, Ove

    2016-10-01

    The investigation of comet 67P by Rosetta has allowed the comprehensive characterisation of pristine cometary dust particles ejected from the nucleus. Flying alongside the comet at distances as small as a few kilometres, and with a relative velocity of only centimetres per second, the Rosetta payload sampled almost unaltered dust. A key instrument to study this dust was MIDAS (the Micro-Imaging Dust Analysis System), a dedicated atomic force microscope that scanned the surfaces of hundreds of (sub-)micrometre sized particles in 3D with resolutions down to nanometres. This offers the unique opportunity to explore the morphology of smallest cometary dust and expand our current knowledge about cometary material.Here we give an overview of dust collected and analysed by MIDAS and highlight its most important features. These include the ubiquitous agglomerate nature of the dust, which is found at all size scales from the largest (>10 µm) through to the smallest (MIDAS resemble primitive interplanetary dust which is a strong argument for a common cometary origin.

  3. Reconstruction of extensive air showers using the MIDAS molecular Bremsstrahlung detector

    International Nuclear Information System (INIS)

    Castro, Andre Ramos de; Bonifazi, Carla; Santos, Edivaldo Moura; Soares, Elvis do Amaral; Mello Neto, Joao Ramos Torres de; Almeida, Rogerio Menezes de

    2011-01-01

    Full text: The weakly ionized plasma created in the atmosphere after the passage of an Extensive Air Shower (EAS) gives rise to the emission of continuous radiation known as Molecular Bremsstrahlung Radiation (MBR) as free electrons scatter off neutral nitrogen (and less frequently oxygen) molecules. The isotropic and unpolarized nature of MBR rises the possibility of an EAS detection similar to that using fluorescence telescopes to capture the ultraviolet light emitted by the ionized nitrogen molecules. The MBR emission, however, falls into the centimeter wavelength range, requiring the use of radio/microwave antennas instead of optical telescopes. In order to test the feasibility of the technique, the MIDAS (Microwave Detection of Air Showers) Collaboration has built a prototype detector where a parabolical reflector illuminates a multi-pixel camera of commercial TV satellite C-band (3.4-4.2 GHz) feeds. This work addresses the geometrical reconstruction of EAS induced by Ultra High Energy Cosmic Rays (UHECR) using the MIDAS detector. The reconstruction chain is similar to that currently applied to the Auger Fluorescence detector events. We have simulated the shower MBR emission assuming two different scenarios: coherent and incoherent emission, i.e., radiation intensity scaling quadratically and linearly with the energy of the primary particle. The MIDAS prototype detector's response is then simulated. Finally, given the simulated events in real data format, we reconstruct the shower's arrival direction, including direction uncertainties and estimate the expected rate of observed events. (author)

  4. Effects of midas® on nematodes in commercial floriculture production in Florida.

    Science.gov (United States)

    Kokalis-Burelle, Nancy; Rosskopf, Erin N; Albano, Joseph P; Holzinger, John

    2010-03-01

    Cut flower producers currently have limited options for nematode control. Four field trials were conducted in 2006 and 2007 to evaluate Midas® (iodomethane:chloropicrin 50:50) for control of root-knot nematodes (Meloidogyne arenaria) on Celosia argentea var. cristata in a commercial floriculture production field in southeastern Florida. Midas (224 kg/ha) was compared to methyl bromide:chloropicrin (98:2, 224 kg/ha), and an untreated control. Treatments were evaluated for effects on Meloidogyne arenaria J2 and free-living nematodes in soil through each season, and roots at the end of each season. Plant growth and root disease were also assessed. Population levels of nematodes isolated from soil were highly variable in all trials early in the season, and generally rebounded by harvest, sometimes to higher levels in fumigant treatments than in the untreated control. Although population levels of nematodes in soil were not significantly reduced during the growing season, nematodes in roots and galling at the end of the season were consistently reduced with both methyl bromide and Midas compared to the untreated control. Symptoms of phytotoxicity were observed in Midas treatments during the first year and were attributed to Fe toxicity. Fertilization was adjusted during the second year to investigate potential fumigant/fertilizer interactions. Interactions occurred at the end of the fourth trial between methyl bromide and fertilizers with respect to root-knot nematode J2 isolated from roots and galling. Fewer J2 were isolated from roots treated with a higher level of Fe (3.05%) in the form of Fe sucrate, and galling was reduced in methyl bromide treated plots treated with this fertilizer compared to Fe EDTA. Reduced galling was also seen with Midas in Fe sucrate fertilized plots compared to Fe EDTA. This research demonstrates the difficulty of reducing high root-knot nematode population levels in soil in subtropical conditions in production fields that have been

  5. Preliminary Study on the Development of MIDAS/GCR to Simulate the Plate-out Phenomena from a HTGR

    International Nuclear Information System (INIS)

    Park, Jong-Hwa; Kim, Dong-Ha; Lee, Won-Jae

    2006-01-01

    In HTGR, the dominant removal mechanism of the condensable fission product gas is a 'plate-out' on various kinds of surfaces over the primary coolant loop. The plate-outs are complex phenomena that are dependent on the mass transfer rate from the coolant to the fixed surface, the adsorption and desorption of the gas fission product, the material of the surfaces, the operation temperature, the fission product species, etc. In a normal operation, the important information on a plate-out is the amount and the distribution and the type of isotope. This information is applied to construct a safety engineering system, to calculate the necessary shielding and to estimate the impact on the environment. The status of a model development and available data are performed extensively but the data still has a large uncertainty. The objective of this study is to compare the condensation model of a gas fission product in the MIDAS for a PWR with the PADLOC model for a HTGR developed by GA and to perform a feasibility calculation on OGL-1 with MIDAS. The results of the model review on MIDAS and PADLOC, the feasibility calculation results on OGL-1 with MIDAS and the phenomena to be implemented into MIDAS to simulate the plate-out phenomena from HTGR are identified and listed

  6. Dansk oversættelse af MiDAS, et redskab til assessment af musikterapi for personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Lykkegaard, Chris; McDermott, Orii

    2018-01-01

    Music in Dementia Assessment Scales, MiDAS, er udviklet til at vurdere ændringer i trivsel hos borgere med demens som har deltaget i musikterapi. Målingen udføres af 1) personale før og efter musikterapien for at vurdere om der er en indflydelse i hverdagssituationer efterfølgende, eller af 2......) musikterapeuten umiddelbart efter sessionen for at vurdere forandringer i selve sessionen. Der har været stor interesse for at anvende MiDAS i flere Europæiske lande, herunder Danmark. Derfor undersøgte udviklerne af MiDAS hvilke procedurer der anvendes til oversættelse og kulturel tilpasning af...... assessmentredskaber, og anbefalede på den baggrund en ti-trins procedure. Vi anvendte denne procedure til oversættelsen af MiDAS og således udviklingen af den danske MiDAS-DK. Den danske version af MiDAS er afprøvet af mere end 20 fagpersoner på baggrund af 296 udfyldte MiDAS-skemaer. Målet med artiklen er...

  7. Enriquecimento da dieta do bicho-da-seda com extrato hidrossolúvel de soja Enrichment of the silkworms diet with soybean water soluble extract

    Directory of Open Access Journals (Sweden)

    Gustavo do Valle Polycarpo

    2012-09-01

    Full Text Available O objetivo deste trabalho foi avaliar se a suplementação da dieta do bicho-da-seda com extrato hidrossolúvel de soja (EHS interfere na produção de casulos e no consumo de folhas de amoreira (Morus alba L. de diferentes cultivares pelas lagartas. O delineamento experimental utilizado foi o inteiramente casualizado em esquema fatorial 4x5, com quatro cultivares de amoreira ('IZ64', 'IZ56/4', 'FM86' e 'FMSM' e cinco dietas (folhas não tratadas, folhas umedecidas com água, folhas enriquecidas com EHS, em três níveis: suplementação da dieta com 5, 10 e 20% de PB. O EHS foi aspergido sobre as folhas, tendo a água como agente dispersante. O consumo foi verificado pela diferença entre a quantidade de folhas fornecidas e a quantidade não consumida pelas lagartas. A ingestão de alimento apresentou-se de forma quadrática, diminuindo à medida que o EHS foi adicionado à dieta. Houve interação dos fatores cultivar e dieta. O fornecimento de folhas de amoreira com acréscimo proteico de 10% por meio do EHS melhorou a qualidade dos casulos do bicho-da-seda com a utilização das cultivares 'IZ56/4' e 'FMSM'. A pulverização de EHS nas folhas da cultivar 'IZ64' prejudicou a produção de casulos. Lagartas do bicho-da-seda, alimentadas com folhas de amoreira sem suplementação, produziram cascas séricas mais pesadas com folhas das cultivares 'IZ64' e 'FMSM'. A aspersão de água nas folhas incrementou o peso de cascas séricas produzidas a partir da cultivar 'FM86'. A suplementação da dieta com EHS diminui o consumo da lagarta do bicho-da-seda. A aplicação de EHS influencia a produção de casulos em função da cultivar utilizada.The aim of this research was to assess if the supplementation of the silkworm diet with soybean water soluble extract (WSE interferes on the consumption of mulberry leaves (Morus alba L. by the caterpillars and on cocoon production. The experimental design was completely randomized in factorial arrangement 4x5

  8. Kas teha konteinerklass? / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2011-01-01

    Koolikorraldusest ja koolidesse vastuvõtust Soomes, Saksamaal ja Inglismaal. Arvamusi avaldavad Soomes õpetajana töötavad Tiiu Jürisson ja Arvi Nikkarev, pikaajalise Soomes töötamise kogemusega TLÜ lektor Anu Carlsson ning Saksamaal Hessenis õpetajana töötav Kadri Heller

  9. Kalinini tehas hõivatud

    Index Scriptorium Estoniae

    2002-01-01

    Prantsuse kunstnike Delphine Reisti, Laurent Fauloni, Sebastien Perroud' ja viiuldaja Mathieu Werchowsky ühisnäitus "Four songs for Siivi" Tallinna endises Kalinini tehases. Kunstnikud esitlevad igaüks üht installatsiooni, M. Werchowsky annab mitu kontserti

  10. Snap clutch, a moded approach to solving the Midas touch problem.

    OpenAIRE

    Istance, Howell; Bates, R.; Hyrskykari, A.; Vickers, Stephen

    2008-01-01

    This paper proposes a simple approach to an old problem, that of the 'Midas Touch'. This uses modes to enable different types of mouse behavior to be emulated with gaze and by using gestures to switch between these modes. A light weight gesture is also used to switch gaze control off when it is not needed, thereby removing a major cause of the problem. The ideas have been trialed in Second Life, which is characterized by a feature-rich of set of interaction techniques and a 3D graphical world...

  11. An Integration of the Restructured Melcor for the Midas Computer Code

    International Nuclear Information System (INIS)

    Sunhee Park; Dong Ha Kim; Ko-Ryu Kim; Song-Won Cho

    2006-01-01

    The developmental need for a localized severe accident analysis code is on the rise. KAERI is developing a severe accident code called MIDAS, which is based on MELCOR. In order to develop the localized code (MIDAS) which simulates a severe accident in a nuclear power plant, the existing data structure is reconstructed for all the packages in MELCOR, which uses pointer variables for data transfer between the packages. During this process, new features in FORTRAN90 such as a dynamic allocation are used for an improved data saving and transferring method. Hence the readability, maintainability and portability of the MIDAS code have been enhanced. After the package-wise restructuring, the newly converted packages are integrated together. Depending on the data usage in the package, two types of packages can be defined: some use their own data within the package (let's call them independent packages) and the others share their data with other packages (dependent packages). For the independent packages, the integration process is simple to link the already converted packages together. That is, the package-wise structuring does not require further conversion of variables for the integration process. For the dependent packages, extra conversion is necessary to link them together. As the package-wise restructuring converts only the corresponding package's variables, other variables defined from other packages are not touched and remain as it is. These variables are to be converted into the new types of variables simultaneously as well as the main variables in the corresponding package. Then these dependent packages are ready for integration. In order to check whether the integration process is working well, the results from the integrated version are verified against the package-wise restructured results. Steady state runs and station blackout sequences are tested and the major variables are found to be the same each other. In order to verify the results, the integrated

  12. The collection and analysis of transient test data using the mobile instrumentation data acquisition system (MIDAS)

    International Nuclear Information System (INIS)

    Uncapher, W.L.; Arviso, M.

    1995-01-01

    Packages designed to transport radioactive materials are required to survive exposure to environments defined in Code of Federal Regulations. Cask designers can investigate package designs through structural and thermal testing of full-scale packages, components, or representative models. The acquisition of reliable response data from instrumentation measurement devices is an essential part of this testing activity. Sandia National Laboratories, under the sponsorship of the US Department of Energy (DOE), has developed the Mobile Instrumentation Data Acquisition System (MIDAS) dedicated to the collection and processing of structural and thermal data from regulatory tests

  13. The MIDAS touch for Accurately Predicting the Stress-Strain Behavior of Tantalum

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-02

    Testing the behavior of metals in extreme environments is not always feasible, so material scientists use models to try and predict the behavior. To achieve accurate results it is necessary to use the appropriate model and material-specific parameters. This research evaluated the performance of six material models available in the MIDAS database [1] to determine at which temperatures and strain-rates they perform best, and to determine to which experimental data their parameters were optimized. Additionally, parameters were optimized for the Johnson-Cook model using experimental data from Lassila et al [2].

  14. A restructuring of the CF/EDF packages for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The CF and EDF packages, which allow the user to define the functions of variables in a database and the usage of an external data file, have been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To restructure the code, the data transferring methods of the current MELCOR code are modified and then partially adopted into the CF/EDF packages. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as pointers are used to define their addresses. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type without pointers leading to an efficient memory treatment and an easy understanding of the code. Restructuring of the CF/EDF packages addressed in this paper includes a module development and subroutine modification. The verification has been done by comparing the results of the modified code with those of the existing code and the trends are almost the same to each other. Therefore the similar approach could be extended to the entire code package for code restructuring. It is expected that the code restructuring will accelerate the code's domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  15. Measuring surface salinity in the N. Atlantic subtropical gyre. The SPURS-MIDAS cruise, spring 2013

    Science.gov (United States)

    Font, Jordi; Ward, Brian; Emelianov, Mikhail; Morisset, Simon; Salvador, Joaquin; Busecke, Julius

    2014-05-01

    SPURS-MIDAS (March-April 2013) on board the Spanish R/V Sarmiento de Gamboa was a contribution to SPURS (Salinity Processes in the Upper ocean Regional Study) focused on the processes responsible for the formation and maintenance of the salinity maximum associated to the North Atlantic subtropical gyre. Scientists from Spain, Ireland, France and US sampled the mesoscale and submesoscale structures in the surface layer (fixed points and towed undulating CTD, underway near surface TSG) and deployed operational and experimental drifters and vertical profilers, plus additional ocean and atmospheric data collection. Validation of salinity maps obtained from the SMOS satellite was one of the objectives of the cruise. The cruise included a joint workplan and coordinated sampling with the US R/V Endeavor, with contribution from SPURS teams on land in real time data and analysis exchange. We present here an overview of the different kinds of measurements made during the cruise, as well as a first comparison between SMOS-derived sea surface salinity products and salinity maps obtained from near-surface sampling in the SPURS-MIDAS area and from surface drifters released during the cruise.

  16. Application of the MIDAS approach for analysis of lysine acetylation sites.

    Science.gov (United States)

    Evans, Caroline A; Griffiths, John R; Unwin, Richard D; Whetton, Anthony D; Corfe, Bernard M

    2013-01-01

    Multiple Reaction Monitoring Initiated Detection and Sequencing (MIDAS™) is a mass spectrometry-based technique for the detection and characterization of specific post-translational modifications (Unwin et al. 4:1134-1144, 2005), for example acetylated lysine residues (Griffiths et al. 18:1423-1428, 2007). The MIDAS™ technique has application for discovery and analysis of acetylation sites. It is a hypothesis-driven approach that requires a priori knowledge of the primary sequence of the target protein and a proteolytic digest of this protein. MIDAS essentially performs a targeted search for the presence of modified, for example acetylated, peptides. The detection is based on the combination of the predicted molecular weight (measured as mass-charge ratio) of the acetylated proteolytic peptide and a diagnostic fragment (product ion of m/z 126.1), which is generated by specific fragmentation of acetylated peptides during collision induced dissociation performed in tandem mass spectrometry (MS) analysis. Sequence information is subsequently obtained which enables acetylation site assignment. The technique of MIDAS was later trademarked by ABSciex for targeted protein analysis where an MRM scan is combined with full MS/MS product ion scan to enable sequence confirmation.

  17. The development of Music in Dementia Assessment Scales (MiDAS).

    Science.gov (United States)

    McDermott, Orii; Orrell, Martin; Ridder, Hanne Mette

    2015-07-03

    There is a need to develop an outcome measure specific to music therapy in dementia that reflects a holistic picture of the therapy process and outcome. This study aimed to develop a clinically relevant and scientifically robust music therapy outcome measure incorporating the values and views of people with dementia. Focus groups and interviews were conducted to obtain qualitative data on what music meant to people with dementia and the observed effects of music. Expert and peer consultations were conducted at each stage of the measure development to maximise its content validity. The new measure was field-tested by clinicians in a care home. Feedback from the clinicians and music therapy experts were incorporated during the review and refinement process of the measure. A review of the existing literature, the experiential results and the consensus process enabled the development of the new outcome measure "Music in Dementia Assessment Scales (MiDAS)". Analysis of the qualitative data identified five key areas of the impact of music on people with dementia and they were transformed as the five Visual Analogue Scale (VAS) items: levels of Interest, Response, Initiation, Involvement and Enjoyment. MiDAS comprises the five VAS items and a supplementary checklist of notable positive and negative reactions from the individual. This study demonstrates that it is possible to design and develop an easy to apply and rigorous quantitative outcome measure which has a high level of clinical relevance for people with dementia, care home staff and music therapists.

  18. A Restructuring of the CAV and FDI Package for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Cho, S. W.

    2006-01-01

    As one of the processes for a localized severe accident analysis code, KAERI is developing a severe accident code MIDAS. The MIDAS code is being developed based on MELCOR. The existing data saving method of MELCOR uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. As a most important process for a localized severe accident analysis code, it is needed convenient method for data handling. So, it has been used the new features in FORTRAN90 such as a dynamic allocation for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring in this paper was the CAV and FDI packages. The CAV(cavity) package is responsible for modeling the attack on the basement concrete by hot core materials. The FDI(Fuel Dispersal Interactions) package is responsible for modeling both low and high pressure molten fuel ejection from the RPV into the reactor cavity, control volumes and surfaces. The verification was done through comparing the results before and after the restructuring

  19. Molecular Ionization-Desorption Analysis Source (MIDAS) for Mass Spectrometry: Thin-Layer Chromatography

    Science.gov (United States)

    Winter, Gregory T.; Wilhide, Joshua A.; LaCourse, William R.

    2016-02-01

    Molecular ionization-desorption analysis source (MIDAS), which is a desorption atmospheric pressure chemical ionization (DAPCI) type source, for mass spectrometry has been developed as a multi-functional platform for the direct sampling of surfaces. In this article, its utility for the analysis of thin-layer chromatography (TLC) plates is highlighted. Amino acids, which are difficult to visualize without staining reagents or charring, were detected and identified directly from a TLC plate. To demonstrate the full potential of MIDAS, all active ingredients from an analgesic tablet, separated on a TLC plate, were successfully detected using both positive and negative ion modes. The identity of each of the compounds was confirmed from their mass spectra and compared against standards. Post separation, the chemical signal (blue permanent marker) as reference marks placed at the origin and solvent front were used to calculate retention factor (Rf) values from the resulting ion chromatogram. The quantitative capabilities of the device were exhibited by scanning caffeine spots on a TLC plate of increasing sample amount. A linear curve based on peak are, R2 = 0.994, was generated for seven spots ranging from 50 to 1000 ng of caffeine per spot.

  20. UPTF test 21D counterpart test in the MIDAS test facility

    International Nuclear Information System (INIS)

    Yoon, B. C.; Ah, D. J.; Joo, I. C.; Kwon, T. S.; Park, W. M.; Song, C. H.

    2002-01-01

    This paper describes the experimental results of UPTF Test 21D counterpart tests in the downcomer during the late reflood phase of LBLOCA. The experiments have been performed in the MIDAS test facility using superheated steam and water. The test condition was determined,based on the test results of UPTF Test 21D, by applying the 'modified linear scaling method of 1/4.077 length scale. The tests of ECC direct bypass and void height are performed separately to estimate each phenomena quantitatively. The tests were carried out by varying the injection steam flow rate of intact cold legs widely to investigate the effect of steam flow rate on the direct bypass fraction and void height. In the tests, separate effect tests have been performed in cases of DVI-1,DVI- 2 and DVI-1 and 2 injections to see the direct bypass fraction according to the DVI nozzle combination. From the tests, we found that the fraction of direct ECC bypass and the void height observed in the MIDAS test facility reasonably well agree with those of UPTF test 21- D. It confirms that the applied 'modified linear scaling law' reproduces major thermal hydraulics phenomena in the downcomer during the LBLOCA reflood phase

  1. A Turkish version of myocardial infarction dimensional assessment scale (TR-MIDAS): reliability-validity assesment.

    Science.gov (United States)

    Uysal, Hilal; Ozcan, Şeyda

    2011-06-01

    Many new measuring devices have been developed so that broader psychometric measurements in the coronary artery disease, disease-specific health status measurements, and identification of the broader quality of life can be performed in the recent years. The study was intended to determine whether, and to what extent, MIDAS is a valid and reliable measurement to the patients suffering from myocardial infarction for the first time in Turkey. The research was conducted with the patients hospitalized and treated with myocardial infarction in the cardiology departments of 2 hospitals in Istanbul, Turkey, between 2007 and 2008. Psychometric evaluations of TR-MIDAS were used for validity studies; language validity, content validity, construct validity were examined. For reliability studies; the tool's internal consistency reliability, Cronbach's alpha reliability coefficient, and test-retest reliability were completed. The instrument's content validity index was determined to be "0.95". Principal component analysis revealed six factors with an eigenvalue >1.5. Cronbach's alpha was found to be 0.89 for total scale which was an acceptable value. The total's test-retest reliability was 0.51 (p<0.01). Data obtained at the end of the study supports that Turkish Myocardial Infarction Dimensional Assessment Scale is a valid and reliable instrument as a disease-specific scale to assess the patients' quality of life suffering from myocardial infarction in Turkey. Copyright © 2010 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

  2. MIDAS: Automated Approach to Design Microwave Integrated Inductors and Transformers on Silicon

    Directory of Open Access Journals (Sweden)

    L. Aluigi

    2013-09-01

    Full Text Available The design of modern radiofrequency integrated circuits on silicon operating at microwave and millimeter-waves requires the integration of several spiral inductors and transformers that are not commonly available in the process design-kits of the technologies. In this work we present an auxiliary CAD tool for Microwave Inductor (and transformer Design Automation on Silicon (MIDAS that exploits commercial simulators and allows the implementation of an automatic design flow, including three-dimensional layout editing and electromagnetic simulations. In detail, MIDAS allows the designer to derive a preliminary sizing of the inductor (transformer on the bases of the design entries (specifications. It draws the inductor (transformer layers for the specific process design kit, including vias and underpasses, with or without patterned ground shield, and launches the electromagnetic simulations, achieving effective design automation with respect to the traditional design flow for RFICs. With the present software suite the complete design time is reduced significantly (typically 1 hour on a PC based on Intel® Pentium® Dual 1.80GHz CPU with 2-GB RAM. Afterwards both the device equivalent circuit and the layout are ready to be imported in the Cadence environment.

  3. A restructuring of the MELCOR fission product packages for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The RN1/RN2 packages, which are the fission product-related packages in MELCOR, have been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To do this, the data transferring methods of the current MELCOR code are modified and adopted into the RN1/RN2 package. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to user-defined data type, which leads to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN1/RN2 package addressed in this paper includes a module development, subroutine modification, and the treatment of MELGEN, which generates the data file, as well as MELCOR, which is processing the calculation. The verification has been done by comparing the results of the modified code with those of the existing code. As the trends are similar to each other, it implies that the same approach could be extended to the entire code package. It is expected that the code restructuring will accelerate the code domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  4. Not a simple case - A first comprehensive phylogenetic hypothesis for the Midas cichlid complex in Nicaragua (Teleostei: Cichlidae: Amphilophus).

    Science.gov (United States)

    Geiger, Matthias F; McCrary, Jeffrey K; Schliewen, Ulrich K

    2010-09-01

    Nicaraguan Midas cichlids from crater lakes have recently attracted attention as potential model systems for speciation research, but no attempt has been made to comprehensively reconstruct phylogenetic relationships of this highly diverse and recently evolved species complex. We present a first AFLP (2793 loci) and mtDNA based phylogenetic hypothesis including all described and several undescribed species from six crater lakes (Apoyeque, Apoyo, Asososca Leon, Masaya, Tiscapa and Xiloá), the two great Lakes Managua and Nicaragua and the San Juan River. Our analyses demonstrate that the relationships between the Midas cichlid members are complex, and that phylogenetic information from different markers and methods do not always yield congruent results. Nevertheless, monophyly support for crater lake assemblages from Lakes Apoyeque, Apoyo, A. Leon is high as compared to those from L. Xiloá indicating occurrence of sympatric speciation. Further, we demonstrate that a 'three species' concept for the Midas cichlid complex is inapplicable and consequently that an individualized and voucher based approach in speciation research of the Midas cichlid complex is necessary at least as long as there is no comprehensive revision of the species complex available. Copyright 2010 Elsevier Inc. All rights reserved.

  5. Are sympatrically speciating Midas cichlid fish special? Patterns of morphological and genetic variation in the closely related species Archocentrus centrarchus.

    Science.gov (United States)

    Fruciano, Carmelo; Franchini, Paolo; Raffini, Francesca; Fan, Shaohua; Meyer, Axel

    2016-06-01

    Established empirical cases of sympatric speciation are scarce, although there is an increasing consensus that sympatric speciation might be more common than previously thought. Midas cichlid fish are one of the few substantiated cases of sympatric speciation, and they formed repeated radiations in crater lakes. In contrast, in the same environment, such radiation patterns have not been observed in other species of cichlids and other families of fish. We analyze morphological and genetic variation in a cichlid species (Archocentrus centrarchus) that co-inhabits several crater lakes with the Midas species complex. In particular, we analyze variation in body and pharyngeal jaw shape (two ecologically important traits in sympatrically divergent Midas cichlids) and relate that to genetic variation in mitochondrial control region and microsatellites. Using these four datasets, we analyze variation between and within two Nicaraguan lakes: a crater lake where multiple Midas cichlids have been described and a lake where the source population lives. We do not observe any within-lake clustering consistent across morphological traits and genetic markers, suggesting the absence of sympatric divergence in A. centrarchus. Genetic differentiation between lakes was low and morphological divergence absent. Such morphological similarity between lakes is found not only in average morphology, but also when analyzing covariation between traits and degree of morphospace occupation. A combined analysis of the mitochondrial control region in A. centrarchus and Midas cichlids suggests that a difference between lineages in the timing of crater lake colonization cannot be invoked as an explanation for the difference in their levels of diversification. In light of our results, A. centrarchus represents the ideal candidate to study the genomic differences between these two lineages that might explain why some lineages are more likely to speciate and diverge in sympatry than others.

  6. A China e as novas rotas da seda e o desenvolvimento pacífico: Reflexões sobre hegemonia e o papel da China no contexto internacional

    Directory of Open Access Journals (Sweden)

    Marcos Cordeiro Pires

    2017-12-01

    Full Text Available A iniciativa conhecida como “Cinturão e Rota”, proposta pela China em 2013, é um ousado projeto econômico e geopolítico com o propósito de ampliar e fortalecer a cooperação regional no contexto eurasiático e nas bacias dos Oceanos Pacífico e Índico. O projeto possui dois braços: terrestre e marítimo, respectivamente o cinturão econômico da Rota da Seda e a Rota da Seda Marítima no século XXI. Esta Iniciativa oferece uma oportunidade para se analisar o contexto da política externa chinesa e as estratégias estabelecidas para atingir seus objetivos de longo prazo, como o seu “desenvolvimento pacífico”, a criação de uma ordem mundial multipolar e a reafirmação dos “Cinco Princípios da Coexistência Pacífica”, meios com os quais busca construir um novo modelo de relacionamento entre grandes potências que ajude a superar uma suposta inevitabilidade da “Armadilha de Tucídides”. Para tanto, este artigo está dividido em três partes, além da  Introdução e das Considerações Finais. Em primeiro lugar buscaremos levantar elementos sobre os fundamentos históricos que embasam a formulação atual da política externa da China. Na segunda seção, discutiremos a evolução da política externa chinesa por meio da análise dos documentos e declarações de seus líderes desde 1978, quando se inicia o processo de “Reforma e Abertura”. Por fim, iremos analisar a Iniciativa “Cinturão e Rota” como um exemplo de como na prática a China busca criar os meios para reafirmar as suas intenções pacifistas e inclusivas num contexto geopolítico bastante conturbado. Palavras-Chave: China; hegemonia; Armadilha de Tucídides; Iniciativa Cinturão e Rota

  7. Proshtshai, dollar? / Kenneth Rogoff ; tõlk. Irina Sashtshenkova

    Index Scriptorium Estoniae

    Rogoff, Kenneth

    2008-01-01

    Autor kirjutab dollari nõrgenemisest ja selle alternatiividest rahvusvahelisel valuutaturul ning euro tugevnemisest. Pankurid ja rahandustegelased peaksid hakkama mõtlema, mida teha siis, kui on aeg dollari toetamine lõpetada

  8. Kuus sammu langusest võitjana väljumiseks / Udo Jung, Reinhard Messenbock, Harold Sirkin

    Index Scriptorium Estoniae

    Jung, Udo

    2008-01-01

    Boston Consulting Groupi ettevõtete küsitlusest selgus, et lisaks kulude kärpimisele on ettevõtted tarvitusele võtnud ka teisi meetmeid majandussurutisega võitlemiseks. Kuus soovitust, mida teha

  9. EKKM, mis siis valesti on? : noor kunst / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-

    2007-01-01

    Eesti Kaasaegse Kunsti Muuseumis lõppenud näitusest "Midagi on valesti", kus esinesid Eesti Kunstiakadeemia fotograafia eriala III kursuse tudengid. Kuraator Marco Laimre. Eesti Kaasaegse Kunsti Muuseumis 8. VIII toimunud ümarlauast "Mida teha?"

  10. Külamehe kelder hoiab nahkhiire elus / Matti Masing

    Index Scriptorium Estoniae

    Masing, Matti, 1953-

    2004-01-01

    Vt. ka Meie Maa 27. nov., Koit : Nädal 29. nov., Lääne Elu 4. dets. Erinevate pealk. all. Nahkhiirte talvitumisest keldrites, mida teha nahkhiirte kaitseks ning nahkhiirte uurimisest ja kaitsest Euroopas

  11. Kogenumad opositsioonipoliitikud lahkuvad volikogust Toompeale / Märt Kubo ; interv. Hille Tänavsuu

    Index Scriptorium Estoniae

    Kubo, Märt

    2007-01-01

    Tallinna volikogu Reformierakonna fraktsiooni aseesimees räägib parlamenti minevatest opositsioonipoliitikutest ja mida nad on suutnud volikogus teha, Keskerakonna ainuvõimust, mis Tallinnale kasu ei too. Lisa: Volikogust lähevad riigikokku

  12. Acculturation of Iranians in the United States, the United Kingdom, and the Netherlands A Test of the Multidimensional Individual Difference Acculturation (MIDA) Model

    NARCIS (Netherlands)

    Safdar, S.; Struthers, W.; Van Oudenhoven, J.P.

    The present study tested the generalizability of a multidimensional individual difference acculturation (MIDA) model in three cultural contexts. The model includes three predictor variables (Psychosocial Resources, Connectedness, and Hassles), predicting three outcome adaptation variables (In-Group

  13. The Scope Calculation for the Distribution of the Plate-out in the 'OGL-1' experiment using MIDAS and Its model review

    International Nuclear Information System (INIS)

    Park, Jong-Hwa; Kim, Dong-Ha; Lee, Won-Jae

    2007-01-01

    The scope calculation on the plate-out in the HTGR related OGL-1 experiment using the MIDAS code was performed in the frame of the preliminary study to develop the MIDAS/GCR for simulating the plate-out, dust and tritium in a HTGR. From this scope calculation, the user specified type of the fission product vapor species in the circuit and the distribution of the circuit surface temperature were identified as the important factors that can have a strong effect on the distribution of fission product plate out over the HTGR loop. Also the analytical solution for calculating the plate-out by considering a radioactive decay was derived for MIDAS. These identified factors and the new analytical solution will be taken into account in developing the MIDAS/GCR

  14. A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS).

    Science.gov (United States)

    Unwin, Richard D; Griffiths, John R; Whetton, Anthony D

    2009-01-01

    The application of a targeted mass spectrometric workflow to the sensitive identification of post-translational modifications is described. This protocol employs multiple reaction monitoring (MRM) to search for all putative peptides specifically modified in a target protein. Positive MRMs trigger an MS/MS experiment to confirm the nature and site of the modification. This approach, termed MIDAS (MRM-initiated detection and sequencing), is more sensitive than approaches using neutral loss scanning or precursor ion scanning methodologies, due to a more efficient use of duty cycle along with a decreased background signal associated with MRM. We describe the use of MIDAS for the identification of phosphorylation, with a typical experiment taking just a couple of hours from obtaining a peptide sample. With minor modifications, the MIDAS method can be applied to other protein modifications or unmodified peptides can be used as a MIDAS target.

  15. Evaluation of the Structure Stability of a Plate Girder Bridge Using MIDAS Structure Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eui Soo; Kim, Jong Hyuk [National Forensic Service, Wonju (Korea, Republic of)

    2014-04-15

    Recently, as a means of resolving the issue of legal liability in the event of an accident or a disaster, a wide variety of simulation techniques, such as structural and structure-fluid interaction analysis, have been used in the field of forensic engineering. The plate girder bridge discussed in this paper was being constructed between a pier and an abutment to expand an existing bridge, but an accident whereby the bridge overturned occurred at the end of the concrete laying process for a protective wall. This accident was caused by additional loads not being considered at the time of the design as well as the actual construction being different from the design. The additional loads ultimately generated a negative support force. In this study, we determined the cause of the accident by comparing the structural stability of the original design with that of the additional, non-conforming construction using MIDAS structural analysis.

  16. The meaning of the virtual Midas touch: an ERP study in economic decision making.

    Science.gov (United States)

    Spapé, Michiel M; Hoggan, Eve E; Jacucci, Giulio; Ravaja, Niklas

    2015-03-01

    The Midas touch refers to the altruistic effects of a brief touch. Though these effects have often been replicated, they remain poorly understood. We investigate the psychophysiology of the effect using remotely transmitted, precisely timed, tactile messages in an economic decision-making game called Ultimatum. Participants were more likely to accept offers after receiving a remotely transmitted touch. Furthermore, we found distinct effects of touch on event-related potentials evoked by (a) feedback regarding accepted and rejected offers, (b) decision cues related to proposals, and (c) the haptic and auditory cues themselves. In each case, a late positive effect of touch was observed and related to the P3. Given the role of the P3 in memory-related functions, the results indicate an indirect relationship between touch and generosity that relies on memory. This hypothesis was further tested and confirmed in the positive effects of touch on later proposals. © 2014 Society for Psychophysiological Research.

  17. Post-test analysis for the MIDAS DVI tests using MARS

    International Nuclear Information System (INIS)

    Bae, K. H.; Lee, Y. J.; Kwon, T. S.; Lee, W. J.; Kim, H. C.

    2002-01-01

    Various DVI tests have been performed at MIDAS test facility which is a scaled facility of APR1400 applying a modified linear scale ratio. The evaluation results for the various void height tests and direct bypass tests using a multi-dimensional best-estimate analysis code MARS, show that; (a) MARS code has an advanced modeling capability of well predicting major multi-dimensional thermal-hydraulic phenomena occurring in the downcomer, (b) MARS code under-predicts the steam condensation rates, which in turn causes to over-predict the ECC bypass rates. However, the trend of decrease in steam condensation rate and increase in ECC bypass rate in accordance with the increase in steam flow rate, and the calculation results of the ECC bypass rates under the EM analysis conditions generally agree with the test data

  18. Evaluation of the Structure Stability of a Plate Girder Bridge Using MIDAS Structure Analysis

    International Nuclear Information System (INIS)

    Kim, Eui Soo; Kim, Jong Hyuk

    2014-01-01

    Recently, as a means of resolving the issue of legal liability in the event of an accident or a disaster, a wide variety of simulation techniques, such as structural and structure-fluid interaction analysis, have been used in the field of forensic engineering. The plate girder bridge discussed in this paper was being constructed between a pier and an abutment to expand an existing bridge, but an accident whereby the bridge overturned occurred at the end of the concrete laying process for a protective wall. This accident was caused by additional loads not being considered at the time of the design as well as the actual construction being different from the design. The additional loads ultimately generated a negative support force. In this study, we determined the cause of the accident by comparing the structural stability of the original design with that of the additional, non-conforming construction using MIDAS structural analysis

  19. The MIDAS experiment: A prototype for the microwave emission of Ultra-High Energy Cosmic Rays

    International Nuclear Information System (INIS)

    Monasor, M.; Alekotte, I.; Alvarez-Muniz, J.; Berlin, A.; Bertou, X.; Bodgan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.; Mello Neto, J.R.T. de; Genat, J.F.; Facal San Luis, P.; Mills, E.; Rouille d'Orfeuil, B.; Wayne, S.; Reyes, L.C.; Santos, E.M.; Privitera, P.; Williams, C.; Zas, E.

    2011-01-01

    Recent measurements suggest that extensive air showers initiated by ultra-high energy cosmic rays (UHECR) emit signals in the microwave band of the electromagnetic spectrum caused by the collisions of the free-electrons with the atmospheric neutral molecules in the plasma produced by the passage of the shower. Such emission is isotropic and could allow the detection of air showers with 100% duty cycle and a calorimetric-like energy measurement, a significant improvement over current detection techniques. We have built MIDAS (MIcrowave Detection of Air Showers), a prototype of microwave detector, which consists of a 4.5 m diameter antenna with a cluster of 53 feed-horns in the 4 GHz range. The details of the prototype and first results will be presented.

  20. A Restructuring of the HS Package for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2005-01-01

    As one of the processes for a localized severe accident analysis code, KAERI is developing a severe accident code MIDAS, based on MELCOR. The existing data saving method uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. But new features in FORTRAN90 such as a dynamic allocation have been used for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring was the HS package which is responsible for calculation the heat conduction within an intact, solid structure and energy transfer across its boundary surfaces into control volumes. The verification was done through comparing the results before and after the restructuring

  1. A restructuring of the FL package for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2005-01-01

    The developmental need for a localized severe accident analysis code is on the rise, and KAERI is developing a severe accident code MIDAS, based on MELCOR. The existing data saving method uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. But new features in FORTRAN90 such as a dynamic allocation have been used for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring was the FL package which is responsible for modeling the thermal-hydraulic behavior of a liquid water, water vapor, and gases in MELCOR with the CVH package. The verification was done through comparing the results before and after the restructuring

  2. Hot money and China's stock market volatility: Further evidence using the GARCH-MIDAS model

    Science.gov (United States)

    Wei, Yu; Yu, Qianwen; Liu, Jing; Cao, Yang

    2018-02-01

    This paper investigates the influence of hot money on the return and volatility of the Chinese stock market using a nonlinear Granger causality test and a new GARCH-class model based on mixed data sampling regression (GARCH-MIDAS). The empirical results suggest that no linear or nonlinear causality exists between the growth rate of hot money and the Chinese stock market return, implying that the Chinese stock market is not driven by hot money and vice versa. However, hot money has a significant positive impact on the long-term volatility of the Chinese stock market. Furthermore, the dependence between the long-term volatility caused by hot money and the total volatility of the Chinese stock market is time-variant, indicating that huge volatilities in the stock market are not always triggered by international speculation capital flow and that Chinese authorities should further focus on more systemic reforms in the trading rules and on effectively regulating the stock market.

  3. Long- and Short-Term Cryptocurrency Volatility Components: A GARCH-MIDAS Analysis

    Directory of Open Access Journals (Sweden)

    Christian Conrad

    2018-05-01

    Full Text Available We use the GARCH-MIDAS model to extract the long- and short-term volatility components of cryptocurrencies. As potential drivers of Bitcoin volatility, we consider measures of volatility and risk in the US stock market as well as a measure of global economic activity. We find that S&P 500 realized volatility has a negative and highly significant effect on long-term Bitcoin volatility. The finding is atypical for volatility co-movements across financial markets. Moreover, we find that the S&P 500 volatility risk premium has a significantly positive effect on long-term Bitcoin volatility. Finally, we find a strong positive association between the Baltic dry index and long-term Bitcoin volatility. This result shows that Bitcoin volatility is closely linked to global economic activity. Overall, our findings can be used to construct improved forecasts of long-term Bitcoin volatility.

  4. Identification and characterization of miRNAs transcriptome in the South African abalone, Haliotis midae.

    Science.gov (United States)

    Picone, Barbara; Rhode, Clint; Roodt-Wilding, Rouvay

    2017-02-01

    Aquatic animal diseases are one of the most important limitations to the growth of aquaculture. miRNAs represent an important class of small ncRNAs able to modulate host immune and stress responses. In Mollusca, a large phylum of invertebrates, miRNAs have been identified in several species. The current preliminary study identified known miRNAs from the South African abalone, Haliotis midae. The economic and ecological importance of abalone makes this species a suitable model for studying and understanding stress response in marine gastropods. Furthermore, the identification of miRNA, represents an alternative and powerful tool to combat infectious disease. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. A midas plugin to enable construction of reproducible web-based image processing pipelines.

    Science.gov (United States)

    Grauer, Michael; Reynolds, Patrick; Hoogstoel, Marion; Budin, Francois; Styner, Martin A; Oguz, Ipek

    2013-01-01

    Image processing is an important quantitative technique for neuroscience researchers, but difficult for those who lack experience in the field. In this paper we present a web-based platform that allows an expert to create a brain image processing pipeline, enabling execution of that pipeline even by those biomedical researchers with limited image processing knowledge. These tools are implemented as a plugin for Midas, an open-source toolkit for creating web based scientific data storage and processing platforms. Using this plugin, an image processing expert can construct a pipeline, create a web-based User Interface, manage jobs, and visualize intermediate results. Pipelines are executed on a grid computing platform using BatchMake and HTCondor. This represents a new capability for biomedical researchers and offers an innovative platform for scientific collaboration. Current tools work well, but can be inaccessible for those lacking image processing expertise. Using this plugin, researchers in collaboration with image processing experts can create workflows with reasonable default settings and streamlined user interfaces, and data can be processed easily from a lab environment without the need for a powerful desktop computer. This platform allows simplified troubleshooting, centralized maintenance, and easy data sharing with collaborators. These capabilities enable reproducible science by sharing datasets and processing pipelines between collaborators. In this paper, we present a description of this innovative Midas plugin, along with results obtained from building and executing several ITK based image processing workflows for diffusion weighted MRI (DW MRI) of rodent brain images, as well as recommendations for building automated image processing pipelines. Although the particular image processing pipelines developed were focused on rodent brain MRI, the presented plugin can be used to support any executable or script-based pipeline.

  6. Testing the carotenoid trade-off hypothesis in the polychromatic Midas cichlid, Amphilophus citrinellus.

    Science.gov (United States)

    Lin, Susan M; Nieves-Puigdoller, Katherine; Brown, Alexandria C; McGraw, Kevin J; Clotfelter, Ethan D

    2010-01-01

    Many animals use carotenoid pigments derived from their diet for coloration and immunity. The carotenoid trade-off hypothesis predicts that, under conditions of carotenoid scarcity, individuals may be forced to allocate limited carotenoids to either coloration or immunity. In polychromatic species, the pattern of allocation may differ among individuals. We tested the carotenoid trade-off hypothesis in the Midas cichlid, Amphilophus citrinellus, a species with two ontogenetic color morphs, barred and gold, the latter of which is the result of carotenoid expression. We performed a diet-supplementation experiment in which cichlids of both color morphs were assigned to one of two diet treatments that differed only in carotenoid content (beta-carotene, lutein, and zeaxanthin). We measured integument color using spectrometry, quantified carotenoid concentrations in tissue and plasma, and assessed innate immunity using lysozyme activity and alternative complement pathway assays. In both color morphs, dietary carotenoid supplementation elevated plasma carotenoid circulation but failed to affect skin coloration. Consistent with observable differences in integument coloration, we found that gold fish sequestered more carotenoids in skin tissue than barred fish, but barred fish had higher concentrations of carotenoids in plasma than gold fish. Neither measure of innate immunity differed between gold and barred fish, or as a function of dietary carotenoid supplementation. Lysozyme activity, but not complement activity, was strongly affected by body condition. Our data show that a diet low in carotenoids is sufficient to maintain both coloration and innate immunity in Midas cichlids. Our data also suggest that the developmental transition from the barred to gold morph is not accompanied by a decrease in innate immunity in this species.

  7. A Midas Plugin to Enable Construction of Reproducible Web-based Image Processing Pipelines

    Directory of Open Access Journals (Sweden)

    Michael eGrauer

    2013-12-01

    Full Text Available Image processing is an important quantitative technique for neuroscience researchers, but difficult for those who lack experience in the field. In this paper we present a web-based platform that allows an expert to create a brain image processing pipeline, enabling execution of that pipeline even by those biomedical researchers with limited image processing knowledge. These tools are implemented as a plugin for Midas, an open-source toolkit for creating web based scientific data storage and processing platforms. Using this plugin, an image processing expert can construct a pipeline, create a web-based UI, manage jobs, and visualize intermediate results. Pipelines are executed on a grid computing platform using BatchMake and HTCondor. This represents a new capability for biomedical researchers and offers an innovative platform for scientific collaboration. Current tools work well, but can be inaccessible for those lacking image processing expertise. Using this plugin, researchers in collaboration with image processing experts can create workflows with reasonable default settings and streamlined user interfaces, and data can be processed easily from a lab environment without the need for a powerful desktop computer. This platform allows simplified troubleshooting, centralized maintenance, and easy data sharing with collaborators. These capabilities enable reproducible science by sharing datasets and processing pipelines between collaborators. In this paper, we present a description of this innovative Midas plugin, along with results obtained from building and executing several ITK based image processing workflows for diffusion weighted MRI (DW MRI of rodent brain images, as well as recommendations for building automated image processing pipelines. Although the particular image processing pipelines developed were focused on rodent brain MRI, the presented plugin can be used to support any executable or script-based pipeline.

  8. Gonad development in Midas cichlids and the evolution of sex change in fishes.

    Science.gov (United States)

    Oldfield, Ronald G

    2011-01-01

    Some fishes mature and function as one sex and later transform to the other sex in response to social interactions. Previous evidence suggested that a change in developmental timing may be involved in the evolution of adult sex change in fishes. The most recent support for this idea came from reports that sex in the Midas cichlid, Amphilophus citrinellus, was determined by social conditions experienced at the juvenile stage. Differentiation as a male was reported to be dependent on large body size relative to group-mates, and thought to be mediated through aggressive interactions. Here I demonstrate that socially controlled sex determination does not occur as was originally reported. Previously, I found that sex was not associated with body size in juveniles either in nature or in captivity. Similarly, I found no association between aggressive behavior and sex in juveniles. I later demonstrated that socially controlled sex determination does not typically occur in the Midas cichlid and closely related species and supported an alternative mechanism to explain large body size in adult males. Finally, in the current study I analyze gonad histology of fish from the same population used by the original authors and lay to rest the idea of socially controlled sex determination in this species. Recent observations of socially controlled sex determination in juveniles of species that typically change sex at the adult stage are examples of phenotypic plasticity, not genetic variation. Therefore, juvenile socially controlled sex determination does not support a theory that a change in developmental timing is involved in the evolution of adult sex change in fishes. © 2011 Wiley Periodicals, Inc.

  9. The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia.

    Science.gov (United States)

    Venter, Leonie; Loots, Du Toit; Mienie, Lodewyk J; Jansen van Rensburg, Peet J; Mason, Shayne; Vosloo, Andre; Lindeque, Jeremie Z

    2018-03-23

    Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy metabolism during functional hypoxia, and the contribution of different metabolic pathways and various abalone tissues towards the overall accumulation of anaerobic end-products in abalone are scarce. Metabolomics analysis of adductor muscle, foot muscle, left gill, right gill, haemolymph and epipodial tissue samples indicated that South African abalone ( Haliotis midae) subjected to functional hypoxia utilises predominantly anaerobic metabolism, and depends on all of the main metabolite classes (proteins, carbohydrates and lipids) for energy supply. Functional hypoxia caused increased levels of anaerobic end-products: lactate, alanopine, tauropine, succinate and alanine. Also, elevation in arginine levels was detected, confirming that abalone use phosphoarginine to generate energy during functional hypoxia. Different tissues showed varied metabolic responses to hypoxia, with functional hypoxia showing excessive changes in the adductor muscle and gills. From this metabolomics investigation, it becomes evident that abalone are metabolically able to produce sufficient amounts of energy when functional hypoxia is experienced. Also, tissue interplay enables the adjustment of H. midae energy requirements as their metabolism shifts from aerobic to anaerobic respiration during functional hypoxia.This article has an associated First Person interview with the first author of the paper. © 2018. Published by The Company of Biologists Ltd.

  10. The cross-tissue metabolic response of abalone (Haliotis midae to functional hypoxia

    Directory of Open Access Journals (Sweden)

    Leonie Venter

    2018-03-01

    Full Text Available Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy metabolism during functional hypoxia, and the contribution of different metabolic pathways and various abalone tissues towards the overall accumulation of anaerobic end-products in abalone are scarce. Metabolomics analysis of adductor muscle, foot muscle, left gill, right gill, haemolymph and epipodial tissue samples indicated that South African abalone (Haliotis midae subjected to functional hypoxia utilises predominantly anaerobic metabolism, and depends on all of the main metabolite classes (proteins, carbohydrates and lipids for energy supply. Functional hypoxia caused increased levels of anaerobic end-products: lactate, alanopine, tauropine, succinate and alanine. Also, elevation in arginine levels was detected, confirming that abalone use phosphoarginine to generate energy during functional hypoxia. Different tissues showed varied metabolic responses to hypoxia, with functional hypoxia showing excessive changes in the adductor muscle and gills. From this metabolomics investigation, it becomes evident that abalone are metabolically able to produce sufficient amounts of energy when functional hypoxia is experienced. Also, tissue interplay enables the adjustment of H. midae energy requirements as their metabolism shifts from aerobic to anaerobic respiration during functional hypoxia. This article has an associated First Person interview with the first author of the paper.

  11. Midazolam: uma nova alternativa para sedação em odontopediatria = Midazolam: a new alternative to sedation in pediatric dentistry

    Directory of Open Access Journals (Sweden)

    Duque, Cristiane

    2005-01-01

    Full Text Available Na prática clínica, existem muitas crianças imaturas e ansiosas ou pacientes com comprometimento físico e/ou mental que não cooperam durante o tratamento odontológico. A sedação pré-operatória é uma das alternativas que facilitam o manejo desses pacientes. O midazolam é um benzodiazepínico que pode ser indicado para crianças, como pré-medicação em procedimentos de curta duração. Isso porque apresenta propriedades hipnóticas e sedativas, além de ser absorvido e eliminado rapidamente pelo organismo. Dessa forma, o objetivo deste estudo é avaliar, por meio de uma revisão de literatura, a efetividade do midazolam, administrado por via oral e intranasal, como agente sedativo para crianças não cooperadoras submetidas a tratamento odontológico

  12. [Cross-cultural adaptation of the Myocardial Infarction Dimensional Assessment Scale (MIDAS) to the Brazilian Portuguese language].

    Science.gov (United States)

    Fiorin, Bruno Henrique; Oliveira, Elizabete Regina Araújo de; Moreira, Rita Simone Lopes; Luna Filho, Bráulio

    2018-03-01

    From the evaluation of the factors that affect quality of life (QOL) it is possible to plan interventions that lead to the improved well-being of patients. The scope of this study was to conduct the cross-cultural adaptation of the Myocardial Infarction Dimensional Assessment Scale (MIDAS) questionnaire to the Portuguese language, seeking the necessary semantic, idiomatic, conceptual and cultural equivalence. The theoretical framework of Guillemin, Bombardier and Beaton was used, fulfilling the following steps: translation, back translation, evaluation of the authors, peer review and pre-testing. After all the tests, the semantic, idiomatic, conceptual and cultural equivalence was achieved. The scale proved to be easy to use and was clinically important. MIDAS was validated in terms of its semantic, idiomatic, conceptual and cultural equivalences. Subsequently, the measurement equivalence will be evaluated to verify the psychometric properties.

  13. MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

    DEFF Research Database (Denmark)

    Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

    activated sludge wastewater treatment systems, linking their identity with available information on their function and distribution. The guide includes the approx. 100 abundant genera that are present in most treatment plants (based on a survey of 25 full-scale Danish wastewater treatment plants...... are provided. The MiDAS Field Guide is a continuously developing resource where all working in the field are invited to contribute....... that would be otherwise excluded from analyses. The MiDAS database importantly provides a common taxonomy for the field that gives a solid foundation for the study of microbial ecology of the activated sludge process and related wastewater treatment processes, such as biofilms and granular sludge. Each genus...

  14. Phylogeography, colonization and population history of the Midas cichlid species complex (Amphilophus spp. in the Nicaraguan crater lakes

    Directory of Open Access Journals (Sweden)

    Meyer Axel

    2010-10-01

    Full Text Available Abstract Background Elucidation of the mechanisms driving speciation requires detailed knowledge about the phylogenetic relationships and phylogeography of the incipient species within their entire ranges as well as their colonization history. The Midas cichlid species complex Amphilophus spp. has been proven to be a powerful model system for the study of ecological specialization, sexual selection and the mechanisms of sympatric speciation. Here we present a comprehensive and integrative phylogeographic analysis of the complete Midas Cichlid species complex in Nicaragua (> 2000 individuals covering the entire distributional range, using two types of molecular markers (the mitochondrial DNA control region and 15 microsatellites. We investigated the majority of known lake populations of this species complex and reconstructed their colonization history in order to distinguish between alternative speciation scenarios. Results We found that the large lakes contain older and more diverse Midas Cichlid populations, while all crater lakes hold younger and genetically less variable species assemblages. The large lakes appear to have repeatedly acted as source populations for all crater lakes, and our data indicate that faunal exchange among crater lakes is extremely unlikely. Despite their very recent (often only a few thousand years old and common origin from the two large Nicaraguan lakes, all crater lake Midas Cichlid radiations underwent independent, but parallel, evolution, and comprise distinct genetic units. Indeed several of these crater lakes contain multiple genetically distinct incipient species that most likely arose through sympatric speciation. Several crater lake radiations can be traced back to a single ancestral line, but some appear to have more than one founding lineage. The timing of the colonization(s of each crater lake differs, although most of them occurred more (probably much more recently than 20,000 years ago. Conclusion The

  15. MiDas: automatic extraction of a common domain of discourse in sleep medicine for multi-center data integration.

    Science.gov (United States)

    Sahoo, Satya S; Ogbuji, Chimezie; Luo, Lingyun; Dong, Xiao; Cui, Licong; Redline, Susan S; Zhang, Guo-Qiang

    2011-01-01

    Clinical studies often use data dictionaries with controlled sets of terms to facilitate data collection, limited interoperability and sharing at a local site. Multi-center retrospective clinical studies require that these data dictionaries, originating from individual participating centers, be harmonized in preparation for the integration of the corresponding clinical research data. Domain ontologies are often used to facilitate multi-center data integration by modeling terms from data dictionaries in a logic-based language, but interoperability among domain ontologies (using automated techniques) is an unresolved issue. Although many upper-level reference ontologies have been proposed to address this challenge, our experience in integrating multi-center sleep medicine data highlights the need for an upper level ontology that models a common set of terms at multiple-levels of abstraction, which is not covered by the existing upper-level ontologies. We introduce a methodology underpinned by a Minimal Domain of Discourse (MiDas) algorithm to automatically extract a minimal common domain of discourse (upper-domain ontology) from an existing domain ontology. Using the Multi-Modality, Multi-Resource Environment for Physiological and Clinical Research (Physio-MIMI) multi-center project in sleep medicine as a use case, we demonstrate the use of MiDas in extracting a minimal domain of discourse for sleep medicine, from Physio-MIMI's Sleep Domain Ontology (SDO). We then extend the resulting domain of discourse with terms from the data dictionary of the Sleep Heart and Health Study (SHHS) to validate MiDas. To illustrate the wider applicability of MiDas, we automatically extract the respective domains of discourse from 6 sample domain ontologies from the National Center for Biomedical Ontologies (NCBO) and the OBO Foundry.

  16. Phylogeography, colonization and population history of the Midas cichlid species complex (Amphilophus spp.) in the Nicaraguan crater lakes.

    Science.gov (United States)

    Barluenga, Marta; Meyer, Axel

    2010-10-26

    Elucidation of the mechanisms driving speciation requires detailed knowledge about the phylogenetic relationships and phylogeography of the incipient species within their entire ranges as well as their colonization history. The Midas cichlid species complex Amphilophus spp. has been proven to be a powerful model system for the study of ecological specialization, sexual selection and the mechanisms of sympatric speciation. Here we present a comprehensive and integrative phylogeographic analysis of the complete Midas Cichlid species complex in Nicaragua (> 2000 individuals) covering the entire distributional range, using two types of molecular markers (the mitochondrial DNA control region and 15 microsatellites). We investigated the majority of known lake populations of this species complex and reconstructed their colonization history in order to distinguish between alternative speciation scenarios. We found that the large lakes contain older and more diverse Midas Cichlid populations, while all crater lakes hold younger and genetically less variable species assemblages. The large lakes appear to have repeatedly acted as source populations for all crater lakes, and our data indicate that faunal exchange among crater lakes is extremely unlikely. Despite their very recent (often only a few thousand years old) and common origin from the two large Nicaraguan lakes, all crater lake Midas Cichlid radiations underwent independent, but parallel, evolution, and comprise distinct genetic units. Indeed several of these crater lakes contain multiple genetically distinct incipient species that most likely arose through sympatric speciation. Several crater lake radiations can be traced back to a single ancestral line, but some appear to have more than one founding lineage. The timing of the colonization(s) of each crater lake differs, although most of them occurred more (probably much more) recently than 20,000 years ago. The genetic differentiation of the crater lake populations

  17. Imaging of irradiated liver with Tc-99m-sulfur colloid and Tc-99m-IDA

    International Nuclear Information System (INIS)

    Gelfand, M.J.; Saha, S.; Aron, B.S.

    1981-01-01

    In three cases, irradiated regions of liver failed to concentrate Tc-99m-sulfur colloid. In two of these three, imaging with Tc-99m-acetanilide iminodiacetic acid (IDA) agents within five days showed near normal hepatic uptake of this hepatobiliary imaging agent. The hepatic parenchymal cells may be imaged with Tc-99m-IDA in some irradiated regions of liver, despite loss of reticuloendothelial cell function

  18. Differential chromosomal organization between Saguinus midas and Saguinus bicolor with accumulation of differences the repetitive sequence DNA.

    Science.gov (United States)

    Serfaty, Dayane Martins Barbosa; Carvalho, Natália Dayane Moura; Gross, Maria Claudia; Gordo, Marcelo; Schneider, Carlos Henrique

    2017-10-01

    Saguinus is the largest and most complex genus of the subfamily Callitrichinae, with 23 species distributed from the south of Central America to the north of South America with Saguinus midas having the largest geographical distribution while Saguinus bicolor has a very restricted one, affected by the population expansion in the state of Amazonas. Considering the phylogenetic proximity of the two species along with evidence on the existence of hybrids between them, as well as cytogenetic studies on Saguinus describing a conserved karyotypic macrostructure, we carried out a physical mapping of DNA repeated sequences in the mitotic chromosome of both species, since these sequences are less susceptible to evolutionary pressure and possibly perform an important function in speciation. Both species presented 2n = 46 chromosomes; in S. midas, chromosome Y is the smallest. Multiple ribosomal sites occur in both species, but chromosome pairs three and four may be regarded as markers that differ the species when subjected to G banding and distribution of retroelement LINE 1, suggesting that it may be cytogenetic marker in which it can contribute to identification of first generation hybrids in contact zone. Saguinus bicolor also presented differences in the LINE 1 distribution pattern for sexual chromosome X in individuals from different urban fragments, probably due to geographical isolation. In this context, cytogenetic analyses reveal a differential genomic organization pattern between species S. midas and S. bicolor, in addition to indicating that individuals from different urban fragments have been accumulating differences because of the isolation between them.

  19. Computerized back postural assessment in physiotherapy practice: Intra-rater and inter-rater reliability of the MIDAS system.

    Science.gov (United States)

    McAlpine, R T; Bettany-Saltikov, J A; Warren, J G

    2009-01-01

    Assessment of spinal posture during physiotherapy practice is routine, yet few objective measures exist to this end. The Middlesbrough Integrated Digital Assessment System (MIDAS) is a low cost portable system able to record 3D information on posture. The purpose of this study was to assess both the intra-rater and inter-rater reliability of the MIDAS system. Twenty-five healthy subjects were recruited. A repeated measures design was used to record fifteen pre-palpated landmarks on the back of each subject. To limit the sources of variability, the principal researcher palpated the landmarks for each subject. Each of three raters took two measurements on each subject in a standardized upright posture. X (medio-lateral), Y (antero-posterior) and Z (height) landmark positions were recorded via a computer interface. Both intra-rater agreement (mean ICCs - rater 1 r=0.970, rater 2 r=0.965 and rater 3 r=0.965, pMIDAS demonstrated both high inter-rater and intra-rater reliability and provides an objective method for the assessment of posture in physiotherapy practice.

  20. Re-Design and Beat Testing of the Man-Machine Integration Design and Analysis System: MIDAS

    Science.gov (United States)

    Shively, R. Jay; Rutkowski, Michael (Technical Monitor)

    1999-01-01

    The Man-machine Design and Analysis System (MIDAS) is a human factors design and analysis system that combines human cognitive models with 3D CAD models and rapid prototyping and simulation techniques. MIDAS allows designers to ask 'what if' types of questions early in concept exploration and development prior to actual hardware development. The system outputs predictions of operator workload, situational awareness and system performance as well as graphical visualization of the cockpit designs interacting with models of the human in a mission scenario. Recently, MIDAS was re-designed to enhance functionality and usability. The goals driving the redesign include more efficient processing, GUI interface, advances in the memory structures, implementation of external vision models and audition. These changes were detailed in an earlier paper. Two Beta test sites with diverse applications have been chosen. One Beta test site is investigating the development of a new airframe and its interaction with the air traffic management system. The second Beta test effort will investigate 3D auditory cueing in conjunction with traditional visual cueing strategies including panel-mounted and heads-up displays. The progress and lessons learned on each of these projects will be discussed.

  1. Anestesia local e sedação para cirurgia de implante coclear: uma alternativa possível Local anesthesia for cochlear implant surgery: a possible alternative

    Directory of Open Access Journals (Sweden)

    Rogério Hamerschmidt

    2010-10-01

    Full Text Available Aanestesia geral sempre foi motivo de dúvida dos pacientes que vão ser submetidos a qualquer cirurgia, especialmente o implante coclear. Como já realizamos as cirurgias otológicas com anestesia local e sedação, julgamos perfeitamente possível a realização da cirurgia do implante coclear também com esse tipo de anestesia, diminuindo os riscos, a morbidade e os custos para o hospital. OBJETIVOS: Estudo prospectivo para demonstrar a técnica anestésica e cirúrgica utilizada em três casos de adultos submetidos ao implante coclear, avaliando a segurança e a eficácia de tal técnica. MATERIAL E MÉTODOS: Foram feitas três cirurgias de implante coclear, duas com implante Cochlear e uma com Med-EL, sem intercorrências transoperatórias, durante a telemetria e no pós-operatório imediato. RESULTADOS: Os três pacientes adultos tiveram alta hospitalar aproximadamente três horas após a cirurgia, deambulando, sem eventos nauseosos, relatando um pós-operatório mais fácil do que esperavam, mesmo no momento da telemetria intraoperatória. CONCLUSÃO: Anestesia local e sedação é uma alternativa para casos selecionados de pacientes para o implante coclear, principalmente naqueles de mais idade ou que apresentem contraindicação para a anestesia geral, os riscos e a morbidade são menores.The aim of this paper is to illustrate the possibility of performing a cochlear implant surgery with local anesthesia and sedation, the anesthetic technique and the advantages of that in comparison to a general anesthesia. AIMS: prospective study demonstrating the possibility of doing cochlear implant surgery under local anesthesia and sedation. MATERIALS AND METHODS: we describe three successful cases operated under local anesthesia, including neural telemetry and the conditions the patient presented after the surgery, with a very good recovery and no complications during and after the procedure. RESULTS: these three surgeries show the possibility of

  2. Produtividade e qualidade da flor-de-seda em diferentes densidades e sistemas de plantio Productivity and quality of rooster tree in different planting densities and planting systems

    Directory of Open Access Journals (Sweden)

    Maria Verônica Meira de Andrade

    2008-01-01

    Full Text Available Avaliou-se o efeito de dois sistemas de plantio (sem camalhão e com camalhão e de três espaçamentos (1,0 × 1,5 m; 1,5 × 2,0 m; e 2,0 × 2,0 m sobre a qualidade e a produtividade de flor-de-seda aos 60 dias de rebrotação. Utilizou-se o delineamento experimental com blocos casualizados em esquema fatorial 2 × 3 (dois sistemas de manejo do solo e três densidades de plantio com cinco repetições, em parcelas subdivididas no espaço e no tempo. Plantas escolhidas aleatoriamente foram cortadas, separadas por tratamento e analisadas quanto aos teores de matéria seca (MS, matéria orgânica (MO, cinzas, extrato etéreo (EE, proteína bruta (PB, fibra em detergente neutro (FDN, fibra em detergente ácido (FDA, celulose, hemicelulose, lignina, carboidratos não-fibrosos (CNF e carboidratos totais (CT e quanto à produtividade (kg MS/ha. Os sistemas de manejo do solo e as densidades de plantio não influenciaram a composição em MO, cinzas, FDN, EE, lignina, celulose, CNF e CT. As densidades de plantio influenciaram o teor de hemicelulose e FDA. O sistema de manejo do solo com camalhão teve efeito linear decrescente sobre o teor de PB. A maior produtividade de MS (699,72 kg/ha da flor-de-seda foi verificada no sistema de plantio mais adensado (1,0 m × 1,5 m e correspondeu a 6.666 plantas/ha.The effect of two soil handling systems was evaluated (without furrow and with furrow, three spacing (1.0 m × 1.5 m; 1.5 m × 2.0 m and 2.0 m × 2.0 m on the quality and the productivity of rooster tree 60 days after cut. It was used a split-plot (space and time factorial arrangement in a randomized block design. Factors were two soil handling systems and three planting densities (2 × 3 with five replications per treatment. Plants chosen randomly were cut, separated in accordance with treatments and analyed the contents of dry matter (DM, organic matter (OM, mineral matter (MM, ether extract (EE, crude protein (CP, neutral detergent fiber (NDF, acid

  3. Caracterização de oito raças do bicho-da-seda (Bombyx mori L. Characterization of eight silkworm races (Bombyx mori L.

    Directory of Open Access Journals (Sweden)

    Antonio José Porto

    2004-02-01

    Full Text Available O experimento foi conduzido na Estação Experimental de Zootecnia de Gália, do Instituto de Zootecnia, SAA-SP, no ano de 2000. Oito raças de bicho-da-seda, de origem Japonesa e Chinesa foram estudadas (B101, B102, B104, B109, C201, C202, C203, C208 em relação a caracteres biológicos (Ganho de peso total de uma lagarta-GP, Porcentagem de mortalidade-MO, Número de machos-NM, Número de fêmeas-NF, Número de ovos/postura-OP e Porcentagem de eclosão-EC e caracteres de produção de casulo (Peso unitário da glândula sericígena-GS, Peso de 30 cascas séricas-CS, Peso de 30 crisálidas-PC, Teor de seda líquido-TS, Casulos desclassificados-CD, Comprimento do casulo-CC e Largura do casulo-LC. O delineamento experimental foi o inteiramente casualizado, com quatro repetições/raça. Não houve variação entre as raças para GP, MO, NF e OP. A raça B101 apresentou, no geral, um menor NM e uma menor EC. Quanto à produção de casulos, no geral, os melhores resultados foram apresentados pela raça C202, com um bom GS (38% do peso final da lagarta, um dos mais altos CS e TS e valores próximos da média para PC, CD, CC e LC. A raça C201, em relação ao casulo produzido, apresentou os piores resultados.The experiment was developed at Estação Experimental de Zootecnia de Galia - Instituto de Zootecnia, SAA-SP, Gália city, São Paulo, Brazil, on 2000. Eight silkworm races of Japanese and Chinese origin were studied (B101, B102, B104, B109, C201, C202, C203, C208 for biological characters ( Total weight-gain for one caterpillar-GP, Percentage of mortality-MO, Number of male-NM, Number of female-NF, Number of egg/laying-OP and Percentage of eclodibility-EC and for characters of cocoon production (silk gland unitary weight-GS, 30 cocoon shell weight-CS, 30 chrysalis weight-PC, silk net purport -TS, disqualified cocoon-CD, cocoon length-CC and cocoon breadth -LC. It was used a completely randomized design, with four replications/ race. It was

  4. Rapid adaptation to a novel light environment: The importance of ontogeny and phenotypic plasticity in shaping the visual system of Nicaraguan Midas cichlid fish (Amphilophus citrinellus spp.).

    Science.gov (United States)

    Härer, Andreas; Torres-Dowdall, Julián; Meyer, Axel

    2017-10-01

    Colonization of novel habitats is typically challenging to organisms. In the initial stage after colonization, approximation to fitness optima in the new environment can occur by selection acting on standing genetic variation, modification of developmental patterns or phenotypic plasticity. Midas cichlids have recently colonized crater Lake Apoyo from great Lake Nicaragua. The photic environment of crater Lake Apoyo is shifted towards shorter wavelengths compared to great Lake Nicaragua and Midas cichlids from both lakes differ in visual sensitivity. We investigated the contribution of ontogeny and phenotypic plasticity in shaping the visual system of Midas cichlids after colonizing this novel photic environment. To this end, we measured cone opsin expression both during development and after experimental exposure to different light treatments. Midas cichlids from both lakes undergo ontogenetic changes in cone opsin expression, but visual sensitivity is consistently shifted towards shorter wavelengths in crater lake fish, which leads to a paedomorphic retention of their visual phenotype. This shift might be mediated by lower levels of thyroid hormone in crater lake Midas cichlids (measured indirectly as dio2 and dio3 gene expression). Exposing fish to different light treatments revealed that cone opsin expression is phenotypically plastic in both species during early development, with short and long wavelength light slowing or accelerating ontogenetic changes, respectively. Notably, this plastic response was maintained into adulthood only in the derived crater lake Midas cichlids. We conclude that the rapid evolution of Midas cichlids' visual system after colonizing crater Lake Apoyo was mediated by a shift in visual sensitivity during ontogeny and was further aided by phenotypic plasticity during development. © 2017 John Wiley & Sons Ltd.

  5. Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus) - towards understanding gene function and regulatory evolution in an ecological model system for rapid phenotypic diversification.

    Science.gov (United States)

    Kratochwil, Claudius F; Sefton, Maggie M; Liang, Yipeng; Meyer, Axel

    2017-11-23

    The Midas cichlid species complex (Amphilophus spp.) is widely known among evolutionary biologists as a model system for sympatric speciation and adaptive phenotypic divergence within extremely short periods of time (a few hundred generations). The repeated parallel evolution of adaptive phenotypes in this radiation, combined with their near genetic identity, makes them an excellent model for studying phenotypic diversification. While many ecological and evolutionary studies have been performed on Midas cichlids, the molecular basis of specific phenotypes, particularly adaptations, and their underlying coding and cis-regulatory changes have not yet been studied thoroughly. For the first time in any New World cichlid, we use Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus). By adapting existing microinjection protocols, we established an effective protocol for transgenesis in Midas cichlids. Embryos were injected with a Tol2 plasmid construct that drives enhanced green fluorescent protein (eGFP) expression under the control of the ubiquitin promoter. The transgene was successfully integrated into the germline, driving strong ubiquitous expression of eGFP in the first transgenic Midas cichlid line. Additionally, we show transient expression of two further transgenic constructs, ubiquitin::tdTomato and mitfa::eGFP. Transgenesis in Midas cichlids will facilitate further investigation of the genetic basis of species-specific traits, many of which are adaptations. Transgenesis is a versatile tool not only for studying regulatory elements such as promoters and enhancers, but also for testing gene function through overexpression of allelic gene variants. As such, it is an important first step in establishing the Midas cichlid as a powerful model for studying adaptive coding and non-coding changes in an ecological and evolutionary context.

  6. DISTINCT ROLES OF β1 MIDAS, ADMIDAS AND LIMBS CATION-BINDING SITES IN LIGAND RECOGNITION BY INTEGRIN α2β1*

    Science.gov (United States)

    Valdramidou, Dimitra; Humphries, Martin J.; Mould, A. Paul

    2012-01-01

    Integrin-ligand interactions are regulated in a complex manner by divalent cations, and previous studies have identified ligand-competent, stimulatory, and inhibitory cation-binding sites. In collagen-binding integrins, such as α2β1, ligand recognition takes place exclusively at the α subunit I domain. However, activation of the αI domain depends on its interaction with a structurally similar domain in the β subunit known as the I-like or βI domain. The top face of the βI domain contains three cation-binding sites: the metal-ion dependent adhesion site (MIDAS), the ADMIDAS (adjacent to MIDAS) and LIMBS (ligand-associated metal binding site). The role of these sites in controlling ligand binding to the αI domain has yet to be elucidated. Mutation of the MIDAS or LIMBS completely blocked collagen binding to α2β1; in contrast mutation of the ADMIDAS reduced ligand recognition but this effect could be overcome by the activating mAb TS2/16. Hence, the MIDAS and LIMBS appear to be essential for the interaction between αI and βI whereas occupancy of the ADMIDAS has an allosteric effect on the conformation of βI. An activating mutation in the α2 I domain partially restored ligand binding to the MIDAS and LIMBS mutants. Analysis of the effects of Ca2+, Mg2+ and Mn2+ on ligand binding to these mutants showed that the MIDAS is a ligand-competent site through which Mn2+ stimulates ligand binding, whereas the LIMBS is a stimulatory Ca2+-binding site, occupancy of which increases the affinity of Mg2+ for the MIDAS. PMID:18820259

  7. Sedação e analgesia em neonatologia Sedación y analgesia en neonatología Sedation and analgesia in neonatology

    Directory of Open Access Journals (Sweden)

    Yerkes Pereira e Silva

    2007-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A importância do estudo da dor em Neonatologia se deve ao fato de que a sensação de dor e estresse significa sofrimento e desconforto para os recém-nascidos e, apesar desse conhecimento, pouco tem sido feito para minimizá-los. Nessa revisão foram discutidas: a prevenção da dor, as medidas não-farmacológicas e farmacológicas para o seu tratamento e a sedação em recém-nascidos. CONTEÚDO: Várias são as medidas não-farmacológicas que podem ser tomadas com intuito de prevenir a dor nas Unidades de Terapia Intensiva Neonatal e também para tornar o ambiente mais humanizado e menos estressante para os pacientes e seus familiares. O tratamento da dor no recém-nascido consiste em medidas não-farmacológicas (sucção não-nutritiva, glicose e farmacológicas (analgésicos não-opióides, opióides e anestésicos locais. A sedação em recém-nascidos é produzida por fármacos que agem diminuindo a atividade, a ansiedade e a agitação do paciente, podendo levar à amnésia de eventos dolorosos ou não-dolorosos. A sedação pode ser feita pela administração de hidrato de cloral, barbitúricos, propofol e benzodiazepínicos. CONCLUSÕES: A prevenção da dor e a indicação de analgesia devem ser individualizadas e sempre consideradas em todos os recém-nascidos portadores de doenças potencialmente dolorosas e/ou submetidos a procedimentos invasivos, cirúrgicos ou não.JUSTIFICATIVA Y OBJETIVOS: La importancia del estudio del dolor en neonatología se debe al hecho de que la sensación de dolor y de estrés significa sufrimiento e incomodidad para los recién nacidos y, a pesar de ese conocimiento poco se ha hecho para reducirlo. Dentro de esa revisión se discutieron: la prevención del dolor, las medidas no farmacológicas ye farmacológicas para su tratamiento y la sedación en recién nacidos. CONTENIDO: Varias son las medidas no-farmacológicas que pueden ser tomadas con el objetivo de prevenir el

  8. The scanning mechanism for ROSETTA/MIDAS: from an engineering model to the flight model

    Science.gov (United States)

    Le Letty, R.; Barillot, F.; Lhermet, N.; Claeyssen, F.; Yorck, M.; Gavira Izquierdo, J.; Arends, H.

    2001-09-01

    The MIDAS (Micro Imaging Dust Analysis System) instrument jointly developed by IWF Graz (AT) and the Solar Space Division of ESA/ESTEC (NL) will flow on ROSETTA and will analyse the dust of the 46P/Wirtanen comet using an Atomic Force Microscope (AFM). A piezoelectric XYZ stage, used to scan the sample in 3 axis, is part of the instrument and has been fully designed and qualified under the ESA/ESTEC contract no13090/98/NL/MV. Two qualification models (EQM/QM) and two flight models (FM/FSM) have been integrated and fully tested within 18 months. The basic principle of the stage has been described in a previous paper. The XY stage includes a latch mechanism based on two Shape Memory actuators. This paper focuses on the lessons learned during the qualification campaign, especially on the testing activities and on the latch mechanism. The XYZ stage has followed a full qualification campaign including Thermal Vacuum cycles, Random Vibrations tests and lifetime tests. The latch mechanism has been designed and tested with the following features: easiness of locking and refurbishment operations, compatibility with the parallel two degrees of freedom mechanism, low shock device. It has been tested more than 20 times, including 4 tests in the worst case conditions (eg the most demanding power case at -20°C) and 2 times after a vibration test. The results and the parameters influencing the reproducibility are discussed. The functional performances have been assessed using a dedicated test bench. Comments are made on the measurements techniques used to get results independent from the drift effect displayed by the piezo components. The calibration work (static and gain of the position sensors) have played an important role during the testing activities. Several parameters (temperature, piezo drift effect and external forces acting on the stage and coming from the coarse approach mechanism) affects the static position. Because of the limited stroke range of reading of the

  9. Evaluación de la fibroína de seda como biomaterial de soporte para el crecimiento de células mesenquimales estromales de pulpa dental

    Directory of Open Access Journals (Sweden)

    Lyda Caballero Mendez

    2016-06-01

    Full Text Available Objetivo. Evaluar la fibroína de la seda obtenida del gusano de seda Bombyx mori L como material de soporte para el crecimiento de células mesenquimales estromales de pulpa dental (CMPD. Métodos. La fibroína fue obtenida a partir de capullos de gusanos de seda Bombyx mori L criados en la Granja El Pílamo, propiedad de la Universidad Tecnológica de Pereira. Se realizaron procedimientos para obtención de películas de fibroína íntegras y resistentes a condiciones de cultivo. Las CMPD fueron obtenidas a partir de un donante de diente premolar, la pieza dental se cortó con disco de diamante para la obtención de la pulpa que fue sometida a disgregación enzimática. Las células obtenidas se subcultivaron hasta el segundo pase para después ser transferidas a cajas de cultivo que contenían películas de fibroína, se sometieron a condiciones inherentes al proceso de incubación con seguimiento de su crecimiento y viabilidad celular durante 27 días. Resultados. Al final del periodo de incubación, se observaron películas integras, estables y resistentes que permitieron el crecimiento celular. Conclusión. Se plantea el uso de la fibroína como un biopolímero natural que brinda un soporte mecánico, un microambiente óptimo y un mimetismo de la estructura organizacional de los tejidos, postulándose como un potencial biomaterial para procesos de crecimiento de células en Medicina Regenerativa basada en Ingeniería de Tejidos.

  10. A Review of 20 Years of Research on Overdiagnosis and Underdiagnosis in the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) Project.

    Science.gov (United States)

    Zimmerman, Mark

    2016-02-01

    The Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project represents an integration of research methodology into a community-based outpatient practice affiliated with an academic medical centre. The MIDAS project is the largest clinical epidemiological study using semi-structured interviews to assess a wide range of psychiatric disorders in a general clinical outpatient practice. In an early report from the MIDAS project, we found that across diagnostic categories clinicians using unstandardized, unstructured clinical interviews underrecognized diagnostic comorbidity, compared with the results of semi-structured interviews. Moreover, we found that the patients often wanted treatment for symptoms of disorders that were diagnosed as comorbid, rather than principal, conditions. This highlighted the importance, from the patient's perspective, of conducting thorough diagnostic interviews to diagnose disorders that are not related to the patient's chief complaint because patients often desire treatment for these additional diagnoses. While several of the initial papers from the MIDAS project identified problems with the detection of comorbid disorders in clinical practice, regarding the diagnosis of bipolar disorder we observed the emergence of an opposite phenomenon-clinician overdiagnosis. The results from the MIDAS project, along with other studies of diagnosis in routine clinical practice, have brought to the forefront the problem with diagnosis in routine clinical practice. An important question is what do these findings suggest about the community standard of care in making psychiatric diagnoses, and whether and how the standard of care should be changed? The implications are discussed. © The Author(s) 2016.

  11. The development of Music in Dementia Assessment Scales (MiDAS)

    Science.gov (United States)

    McDermott, Orii; Orrell, Martin; Ridder, Hanne Mette

    2015-01-01

    There is a need to develop an outcome measure specific to music therapy in dementia that reflects a holistic picture of the therapy process and outcome. This study aimed to develop a clinically relevant and scientifically robust music therapy outcome measure incorporating the values and views of people with dementia. Focus groups and interviews were conducted to obtain qualitative data on what music meant to people with dementia and the observed effects of music. Expert and peer consultations were conducted at each stage of the measure development to maximise its content validity. The new measure was field-tested by clinicians in a care home. Feedback from the clinicians and music therapy experts were incorporated during the review and refinement process of the measure. A review of the existing literature, the experiential results and the consensus process enabled the development of the new outcome measure “Music in Dementia Assessment Scales (MiDAS)”. Analysis of the qualitative data identified five key areas of the impact of music on people with dementia and they were transformed as the five Visual Analogue Scale (VAS) items: levels of Interest, Response, Initiation, Involvement and Enjoyment. MiDAS comprises the five VAS items and a supplementary checklist of notable positive and negative reactions from the individual. This study demonstrates that it is possible to design and develop an easy to apply and rigorous quantitative outcome measure which has a high level of clinical relevance for people with dementia, care home staff and music therapists. PMID:26246670

  12. Morphology and morphometry of the reproductive system of female Saguinus midas (Linnaeus, 1758).

    Science.gov (United States)

    Monteiro, Nathaly Cristine Da Silva; De Lima, Ana Rita; De Carvalho, Ana Flávia; De Carvalho Garcia, Rafael; Therrier, Joanne; Souza, Ana Carla Barros; Pereira, Luiza Correia; Branco, Erika

    2012-06-01

    In this article, the reproductive system's morphology of three young animals of the species Saguinus midas, from the bauxite mine in Paragominas, is described. The specimens were fixed and preserved in a solution of 10% aqueous formaldehyde, followed by dissection, measurement of the genital organs (uterus, vagina, ovaries, and uterine tubes), and histological processing. The vulva is delimited by the labia, with a clitoris. It is lined by keratinized stratified squamous epithelium with sebaceous glands of holocrine secretion. The vagina is an elongated tube with an average length of 26 mm and diameter of 1 mm, presenting a non-keratinized squamous epithelium, disposed between the vestibule of the vagina and cervix, the latter being relatively short. The uterus is simple, has globular shape and is located in the caudal portion of the abdominal cavity, with an average length of 14 mm and average width of 7 mm. It is formed by vascular and serous layers of muscles, and undergoes a bifurcation to form two structures on the bottom of blind sac. The uterine tubes are long and convoluted with an average length of 35 mm (right) and 36 mm (left), consisting of loose connective tissue and muscle layer lined by simple ciliated columnar epithelium. The ovaries are large and ellipsoid with smooth surface. Histologically, one animal showed ovulation fosse. Copyright © 2011 Wiley Periodicals, Inc.

  13. Iodine bonding stabilizes iodomethane in MIDAS pesticide. Theoretical study of intermolecular interactions between iodomethane and chloropicrin.

    Science.gov (United States)

    Glaser, Rainer; Prugger, Kaitlan

    2012-02-22

    The results are reported of a theoretical study of iodomethane (H(3)C-I, 1) and chloropicrin (Cl(3)C-NO(2), 2), of the heterodimers 3-6 formed by aggregation of 1 and 2, and of their addition products 7 and 8 and their possible fragmentation reactions to 9-18. Mixtures of iodomethane and chloropicrin are not expected to show chemistry resulting from their reactions with each other. The structures and stabilities are discussed of the iodine-bonded molecular aggregates (IBMA) 3 and 4 and of the hydrogen- and iodine-bonded molecular aggregates (IHBMA) 5 and 6. The mixed aggregates 3-5 are bound on the free enthalpy surface relative to the homodimers of 1 and 2, and the IBMA structures 3 and 4 are most stable. This result suggests that the mixture of chloropicrin and iodomethane in the pesticide Midas is a good choice to reduce the volatility of iodomethane because of thermodynamically stabilizing iodine bonding.

  14. Direct ECC bypass phenomena in the MIDAS test facility during LBLOCA reflood phase

    International Nuclear Information System (INIS)

    Yun, B. J.; Kweon, T. S.; Ah, D. J.; Ju, I. C.; Song, C. H.; Park, J. K.

    2001-01-01

    This paper describes the experimental results of ECC Direct Bypass Phenomena in the downcomer during the late reflood phase of LBLOCA of the reactor that adopts Direct Vessel Injection as a ECC system. The experiments have been performed in MIDAS test facility using superheated steam and water. The test condition was determined, based on the preliminary analysis of TRAC code, from modified linear scaling method of 1/4.93 length scale. To measure the direct bypass fraction according to the nozzle location, separate effect tests have been performed in case of DVI-4(farthest from broken cold leg) injection, DVI-2(closest to broken cold leg) injection, and DVI-2 and 4 injection, respectively. Also the test was carried out varying the steam flow rate greatly to investigate the effect of steam flow rate on the direct bypass fraction of ECC water. Test results show that the direct bypass fraction of ECC water depends significantly on the injected steam mass flow rate. DVI-4 tests show that the direct bypass fraction increases drastically as the steam flow rate increases. However, in DVI-2 test most of the injected ECC water penetrates into lower downcomer. The direct bypass characteristic in each of DVI-2 and DVI-4 tests is reflected into the direct bypass characteristic curve of DVI-2 and 4 test. The steam condensation reaches to the theoretically allowable maximum value

  15. A 1ST Step Integration of the Restructured MELCOR for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Cho, S. W.

    2006-01-01

    KAERI is developing a localized severe accident code, MIDAS, based on MELCOR. MELCOR uses pointer variables for a fixed-size storage management to save the data. It passes data through two depths, its meaning is not understandable by variable itself. So it is needed to understand the methods for data passing. This method deteriorates the readability, maintainability and portability of the code. As a most important process for a localized severe accident analysis code, it is needed convenient method for data handling. So, it has been used the new features in FORTRAN90 such as a dynamic allocation for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring for each package was developed and tested. And then integration of each restructured package was being processed one by one. In this paper, the integrating scope includes the BUR, CF, CVH, DCH, EDF, ESF, MP, SPR, TF and TP packages. As most of them use data within each package and a few packages share data with other packages. The verification was done through comparing the results before and after the restructuring

  16. Aggression and welfare in a common aquarium fish, the Midas cichlid.

    Science.gov (United States)

    Oldfield, Ronald G

    2011-01-01

    Many species of fishes are aggressive when placed in small aquaria. Aggression can negatively affect the welfare of those individuals toward whom it is directed. Animals may behave aggressively in order to defend resources such as food, shelter, mates, and offspring. The decision to defend depends on the distribution of resources and on ecological factors such as number of competitors, amount of available space, and amount of habitat complexity. This study tested the effects of these factors on aggression in a common aquarium fish, the Midas cichlid (Amphilophus citrinellus). The study found that time spent behaving aggressively was not associated with small-scale differences in group size or available space. Aggression was significantly lower in a large aquarium with a complex habitat. Aquaria of sizes typically used in the companion animal (pet) hobby did not provide optimal welfare for cichlids housed with aggressive conspecifics. The public should be aware that this and similar species require larger aquaria with complex habitat, which elicit more natural behavior.

  17. A multimodal interface to resolve the Midas-Touch problem in gaze controlled wheelchair.

    Science.gov (United States)

    Meena, Yogesh Kumar; Cecotti, Hubert; Wong-Lin, KongFatt; Prasad, Girijesh

    2017-07-01

    Human-computer interaction (HCI) research has been playing an essential role in the field of rehabilitation. The usability of the gaze controlled powered wheelchair is limited due to Midas-Touch problem. In this work, we propose a multimodal graphical user interface (GUI) to control a powered wheelchair that aims to help upper-limb mobility impaired people in daily living activities. The GUI was designed to include a portable and low-cost eye-tracker and a soft-switch wherein the wheelchair can be controlled in three different ways: 1) with a touchpad 2) with an eye-tracker only, and 3) eye-tracker with soft-switch. The interface includes nine different commands (eight directions and stop) and integrated within a powered wheelchair system. We evaluated the performance of the multimodal interface in terms of lap-completion time, the number of commands, and the information transfer rate (ITR) with eight healthy participants. The analysis of the results showed that the eye-tracker with soft-switch provides superior performance with an ITR of 37.77 bits/min among the three different conditions (pusers.

  18. Robert Putnam : miks peaksime naabritega rohkem rääkima? / Robert Putnam ; interv. Külli-Riin Tigasson

    Index Scriptorium Estoniae

    Putnam, Robert

    2006-01-01

    26. mail Tallinnas toimuva Avatud Ühiskonna Foorumi peaesineja, Harvardi Ülikooli professor väidab, et mida paremini tuntakse oma naabreid, mida aktiivsemalt osaletakse kohalikus elus ning mida rohkem inimesed omavahel suhtlevad, seda paremaks ja turvalisemaks muutub nende elukeskkond. Lisad: Robert Putnam (sünd 1941); Kuidas kasvatada sotsiaalset kapitali?

  19. "Alguses oli tema üksinda, sest oli küll..." : [luuletused] / Kabir ; tlk. Doris Kareva

    Index Scriptorium Estoniae

    Kabir

    2006-01-01

    Sisu: "Alguses oli tema üksinda, sest oli küll..." ; "Kõik loodud on Kõiksuse poolt..." ; "Otsid Sa mind?..." ; "Kabir oma meele puhtaks..." ; "Pole pühades järvedes midagi muud peale vee..." ; "Otsisin kelme ja kõveraid..." ; "Ütle, vend, mida küll teha..." ; "Mis kurja on teinud su juuksed..." ; "Ära tõuse, et minna õue vaatama lilli..." ; "Sinu sünd inimesena on küps vili..." ; "Öö saatsid sa magades mööda..." ; "Pole ma hindu..." ; "Ma vaatan sind..." ; "Veskikivisid vaadeldes ; "Nähes aednikku lähenemas, õhkasid pungad..." ; "Tasa, tasa tõtta, mu meel..." ; "Ära kurvasta..." ; "Imetlusväärne on teemant..." ; "Kuula, sõber, see keha on Tema lüüra..." ; "Nagu seemnes varjul on õli..." ; "Olgugi ookean leekides..." ; "Tilka, mis lahustub meres..." ; "Jõgi ja lained on üks..." ; "Kes sa oled ja kust oled tulnud?..." ; "Kaovad kuningad, kauneimad kuningannad..." ; "Rohkem kui midagi muud..." ; "Lihalik, surelik tantsib selle ees..." ; "Väike rubiin, mida igaüks ihkab..." ; "Mine heade juurde, kus Armastatugi elab..." ; "Eksitus sulgeb väravad..." ; "Keelilt vallandub helisid..." ; "Kõik algab lahusoleku valust..." ; "Ärka, sõber! Miks ikka veel magad?..." ; "Kuu on mu kehas, kuid ise ma seda ei näe..." ; "Miks oled nii kärsitu, süda?..." ; "Kellele kuulub see flööt..." ; "Kui raske on Külalist kohata!..." ; "Kandetool toodi minule järgi mu isakoju..." ; "Siia ilma sündides nutsid..." ; "Oh mu süda! Ei jõudnud sa tundma õppida..." ; "Õige kulunud on sinu rüü..." ; "Õhkõrn on see õhuke rüü..." ; "Lipp, mida keegi ei näe..." ; "Oh otsija, lihtne liit lähim on südamele..." ; "Õhtu varjud on sügavaks saanud..." ; "Kuis saakski katkeda armastus me kahe vahel..." ; "Luik, tahaksin, et mulle räägiksid kõik oma loo..." ; "Kuhu ihaled küll, minu süda?..." ; "Ei lakka Lõpmatu flöödiheli..." ; "Mida näed, seda pole...". Autori kohta eluloolisi andmeid lk. 11

  20. Embryonic and larval development in the Midas cichlid fish species flock (Amphilophus spp.): a new evo-devo model for the investigation of adaptive novelties and species differences.

    Science.gov (United States)

    Kratochwil, Claudius F; Sefton, Maggie M; Meyer, Axel

    2015-02-26

    Central American crater lake cichlid fish of the Midas species complex (Amphilophus spp.) are a model system for sympatric speciation and fast ecological diversification and specialization. Midas cichlids have been intensively analyzed from an ecological and morphological perspective. Genomic resources such as transcriptomic and genomic data sets, and a high-quality draft genome are available now. Many ecologically relevant species-specific traits and differences such as pigmentation and cranial morphology arise during development. Detailed descriptions of the early development of the Midas cichlid in particular, will help to investigate the ontogeny of species differences and adaptations. We describe the embryonic and larval development of the crater lake cichlid, Amphilophus xiloaensis, until seven days after fertilization. Similar to previous studies on teleost development, we describe six periods of embryogenesis - the zygote, cleavage, blastula, gastrula, segmentation, and post-hatching period. Furthermore, we define homologous stages to well-described teleost models such as medaka and zebrafish, as well as other cichlid species such as the Nile tilapia and the South American cichlid Cichlasoma dimerus. Key morphological differences between the embryos of Midas cichlids and other teleosts are highlighted and discussed, including the presence of adhesive glands and different early chromatophore patterns, as well as variation in developmental timing. The developmental staging of the Midas cichlid will aid researchers in the comparative investigation of teleost ontogenies. It will facilitate comparative developmental biological studies of Neotropical and African cichlid fish in particular. In the past, the species flocks of the African Great Lakes have received the most attention from researchers, but some lineages of the 300-400 species of Central American lakes are fascinating model systems for adaptive radiation and rapid phenotypic evolution. The availability

  1. QuBiLS-MIDAS: a parallel free-software for molecular descriptors computation based on multilinear algebraic maps.

    Science.gov (United States)

    García-Jacas, César R; Marrero-Ponce, Yovani; Acevedo-Martínez, Liesner; Barigye, Stephen J; Valdés-Martiní, José R; Contreras-Torres, Ernesto

    2014-07-05

    The present report introduces the QuBiLS-MIDAS software belonging to the ToMoCoMD-CARDD suite for the calculation of three-dimensional molecular descriptors (MDs) based on the two-linear (bilinear), three-linear, and four-linear (multilinear or N-linear) algebraic forms. Thus, it is unique software that computes these tensor-based indices. These descriptors, establish relations for two, three, and four atoms by using several (dis-)similarity metrics or multimetrics, matrix transformations, cutoffs, local calculations and aggregation operators. The theoretical background of these N-linear indices is also presented. The QuBiLS-MIDAS software was developed in the Java programming language and employs the Chemical Development Kit library for the manipulation of the chemical structures and the calculation of the atomic properties. This software is composed by a desktop user-friendly interface and an Abstract Programming Interface library. The former was created to simplify the configuration of the different options of the MDs, whereas the library was designed to allow its easy integration to other software for chemoinformatics applications. This program provides functionalities for data cleaning tasks and for batch processing of the molecular indices. In addition, it offers parallel calculation of the MDs through the use of all available processors in current computers. The studies of complexity of the main algorithms demonstrate that these were efficiently implemented with respect to their trivial implementation. Lastly, the performance tests reveal that this software has a suitable behavior when the amount of processors is increased. Therefore, the QuBiLS-MIDAS software constitutes a useful application for the computation of the molecular indices based on N-linear algebraic maps and it can be used freely to perform chemoinformatics studies. Copyright © 2014 Wiley Periodicals, Inc.

  2. Seda on vaja teada piiril : seda on vaja teada tollis

    Index Scriptorium Estoniae

    1994-01-01

    Kauba deklareerimine, ajutine sisse- ja väljavedu, päritolusertifikaat, piirituse, alk.jookide, õlle ning tubakatoodete vedu; Litsenseeritud kaubad; Puidu import ja eksport; Transiitvedu; Metallide import ja eksport; Televisiooni- ja raadioettevõtete, filmistuudiote ja ajakirjandustöötajate töövahendite tollivormistus; Postisaadetised; Turismi- ja spordilaevade tollivormistus; Mootorikütuse ja -õli import ja eksport; Tagastamatu majandusabi; Üksikisiku kauba kontroll; Deklareerimiskohustus; Kaubad, mille toimet. üle Eesti riigipiiri on keelatud; Kultuuriväärtused; Väärismetallid, vääriskivid ja neid sisaldavad esemed; Relvad; Mootorsõidukid; Tolliladustamine; Veterinaalkontrollile alluvad kaubad; Piirkogused; Tolliinspektuuride aadressid ja telefoninumbrid

  3. The Effect of External Vessel Cooling for a 2 inch LOCA Severe Accident Scenario at SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2010-01-01

    KAERI is developing a new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. This feature may prevent the large size of LOCA. However it is necessary to estimate the hypothetical severe accidents progression for improving the degree of safety and identifying the unknown weakness of the system against an accident. To simulate a hypothetical severe accident for the SMART, we adopt the MIDAS/SMR code which was developed by KAERI

  4. MIDAS-FAST: Design and Validation of a Model-Based Tool to Predict Operator Performance with Robotic Arm Automation

    Science.gov (United States)

    Sebok, Angelia (Principal Investigator); Wickens, Christopher; Gacy, Marc; Brehon, Mark; Scott-Nash, Shelly; Sarter, Nadine; Li, Huiyang; Gore, Brian; Hooey, Becky

    2017-01-01

    The Coalition for Aerospace and Science (CAS) is hosting an exhibition on Capitol Hill on June 14, 2017, to highlight the contributions of CAS members to NASAs portfolio of activities. This exhibition represents an opportunity for an HFES members ground breaking work to be displayed and to build on support within Congress for NASAs human research program including in those areas that are of specific interest to the HFE community. The intent of this poster presentation is to demonstrate the positive outcome that comes from funding HFE related research on a project like the one exemplified by MIDAS-FAST.

  5. Ma tean, mida sa näitad end olevat teinud läinud suvel / Laura Kuusk

    Index Scriptorium Estoniae

    Kuusk, Laura, 1982-

    2006-01-01

    Kuraator Marco Laimre juhendamisel valminud Eesti Kunstiakadeemia III kursuse fotograafiaüliõpilaste suvepraktika tööde näitus "Ma tean, mida sa tegid läinud suvel / I know what you did last summer" Eesti Kunstiakadeemia galeriis kuni 3. X. Helina Kõrmi, Dmitri Gerassimovi, Kristjan-Jaak Tammiksaare, Anne-Mai Pällo, Tuuli Antsovi, Terje Ugandi, Ivar Veermäe, Riika Tauriaineni, Kätly Kaibaldi, Raul Viitungi ja Andrus Kaursoni töödest

  6. Energy Tax versus Carbon Tax. A quantitative macro economical analysis with the HERMES/MIDAS models

    International Nuclear Information System (INIS)

    Karadeloglou, P.

    1992-01-01

    The idea of imposing a tax has been recently put forward as a policy-instrument to induce substitutions aiming at reducing CO[sub 2] overall emissions. One can distinguish two options: recycle tax revenues for energy system restructuring (supply or demand restructuring); or use the corresponding revenues in order to reduce the negative impacts caused on the economic activity by the introduction of the tax. Several papers dealing with only the macroeconomic aspects of the environmental problems have been written. These papers neglect more or less the energy sphere and consider that the energy feedback effects are very small. Macroeconomic impacts of the carbon tax have been examined for the United Kingdom and for the four big European countries elsewhere. In this paper a synthesis of both the energy and the macroeconomic approaches is realized. The approach adopted is global and tries to evaluate the impacts on both the economic and energy system. The main question examined is the effectiveness and impacts of fiscal policy on CO[sub 2] emission and the effects of the adoption of an accommodating policy. Thus, not only the effects of imposing an energy or carbon tax are examined, but also the effects of introducing accommodating measures are studied. The analysis is effected by using the HERMES-MIDAS linked system of models and is limited in analyzing the effects of carbon and energy taxes and the reduction of direct taxes and is effected for four countries namely France, Federal Republic of Germany, Italy and the United Kingdom. In section 2 policy scenarios are described while in sections three and four the results of the policy simulations are presented. In section five we compare the differences of two taxes (energy tax and carbon tax) and in section six the reduction of direct taxation as an accommodating measure is examined. 27 tabs., 10 refs

  7. Constraining Microwave Emission from Extensive Air Showers via the MIDAS Experiment

    Science.gov (United States)

    Richardson, Matthew; Privitera, Paolo

    2017-01-01

    Ultra high energy cosmic rays (UHECRs) are accelerated by the most energetic processes in the universe. Upon entering Earth’s atmosphere they produce particle showers known as extensive air showers (EASs). Observatories like the Pierre Auger Observatory sample the particles and light produced by the EASs through large particle detector arrays or nitrogen fluorescence detectors to ascertain the fundamental properties of UHECRs. The large sample of high quality data provided by the Pierre Auger Observatory can be attributed to the hybrid technique which utilizes the two aforementioned techniques simultaneously; however, the limitation of only being able to observe nitrogen fluorescence from EASs on clear moonless nights yields a limited 10% duty cycle for the hybrid technique. One proposal for providing high quality data at increased statistics is the observation of isotropic microwave emission from EASs, as such emission would be observed with a 100% duty cycle. Measurements of microwave emission from laboratory air plasmas conducted by Gorham et al. (2008) produced promising results indicating that the microwave emission should be observable using inexpensive detectors. The Microwave Detection of Air Showers (MIDAS) experiment was built at the University of Chicago to characterize the isotropic microwave emission from EASs and has collected 359 days of observational data at the location of the Pierre Auger experiment. We have performed a time coincidence analysis between this data and data from Pierre Auger and we report a null result. This result places stringent limits on microwave emission from EASs and demonstrates that the laboratory measurements of Gorham et al. (2008) are not applicable to EASs, thus diminishing the feasibility of using isotropic microwave emission to detect EASs.

  8. MIDA: A Multimodal Imaging-Based Detailed Anatomical Model of the Human Head and Neck.

    Directory of Open Access Journals (Sweden)

    Maria Ida Iacono

    Full Text Available Computational modeling and simulations are increasingly being used to complement experimental testing for analysis of safety and efficacy of medical devices. Multiple voxel- and surface-based whole- and partial-body models have been proposed in the literature, typically with spatial resolution in the range of 1-2 mm and with 10-50 different tissue types resolved. We have developed a multimodal imaging-based detailed anatomical model of the human head and neck, named "MIDA". The model was obtained by integrating three different magnetic resonance imaging (MRI modalities, the parameters of which were tailored to enhance the signals of specific tissues: i structural T1- and T2-weighted MRIs; a specific heavily T2-weighted MRI slab with high nerve contrast optimized to enhance the structures of the ear and eye; ii magnetic resonance angiography (MRA data to image the vasculature, and iii diffusion tensor imaging (DTI to obtain information on anisotropy and fiber orientation. The unique multimodal high-resolution approach allowed resolving 153 structures, including several distinct muscles, bones and skull layers, arteries and veins, nerves, as well as salivary glands. The model offers also a detailed characterization of eyes, ears, and deep brain structures. A special automatic atlas-based segmentation procedure was adopted to include a detailed map of the nuclei of the thalamus and midbrain into the head model. The suitability of the model to simulations involving different numerical methods, discretization approaches, as well as DTI-based tensorial electrical conductivity, was examined in a case-study, in which the electric field was generated by transcranial alternating current stimulation. The voxel- and the surface-based versions of the models are freely available to the scientific community.

  9. Energy Tax versus Carbon Tax. A quantitative macro economical analysis with the HERMES/MIDAS models

    Energy Technology Data Exchange (ETDEWEB)

    Karadeloglou, P. [National Technical University of Athens (Greece)

    1992-03-01

    The idea of imposing a tax has been recently put forward as a policy-instrument to induce substitutions aiming at reducing CO{sub 2} overall emissions. One can distinguish two options: recycle tax revenues for energy system restructuring (supply or demand restructuring); or use the corresponding revenues in order to reduce the negative impacts caused on the economic activity by the introduction of the tax. Several papers dealing with only the macroeconomic aspects of the environmental problems have been written. These papers neglect more or less the energy sphere and consider that the energy feedback effects are very small. Macroeconomic impacts of the carbon tax have been examined for the United Kingdom and for the four big European countries elsewhere. In this paper a synthesis of both the energy and the macroeconomic approaches is realized. The approach adopted is global and tries to evaluate the impacts on both the economic and energy system. The main question examined is the effectiveness and impacts of fiscal policy on CO{sub 2} emission and the effects of the adoption of an accommodating policy. Thus, not only the effects of imposing an energy or carbon tax are examined, but also the effects of introducing accommodating measures are studied. The analysis is effected by using the HERMES-MIDAS linked system of models and is limited in analyzing the effects of carbon and energy taxes and the reduction of direct taxes and is effected for four countries namely France, Federal Republic of Germany, Italy and the United Kingdom. In section 2 policy scenarios are described while in sections three and four the results of the policy simulations are presented. In section five we compare the differences of two taxes (energy tax and carbon tax) and in section six the reduction of direct taxation as an accommodating measure is examined. 27 tabs., 10 refs.

  10. Milline mentor kõik tuksi keerab? Ja milline on hea mentor? / Marit Pajulaid, Agne Puusaar, Kaido Aettik ; kommenteerinud Tiiu Allikvee

    Index Scriptorium Estoniae

    Pajulaid, Marit

    2010-01-01

    Küsimuste üle, milline peab olema hea mentor ning mida ta peaks ja mida ta ei tohiks teha, arutlevad Fontese pooleaastase mentorprogrammi läbinud Fazer Eesti juhtrühma liige Marit Pajulaid, reklaamibüroo Division personalijuht Agne Puusaar ning endine Kuusakoski juhatuse esimees Kaido Aettik

  11. Experimental observation of a multi-dimensional mixing behavior of steam-water flow in the MIDAS test facility

    International Nuclear Information System (INIS)

    Kweon, T. S.; Yun, B. J.; Ah, D. J.; Ju, I. C.; Song, C. H.; Park, J. K.

    2001-01-01

    Multi-dimensional thermal-hydraulic hehavior, such as ECC (Emergency Core Cooling) bypass, ECC penetration, steam-water condensation and accumulated water level, in an annular downcomer of a PWR (Pressurized Water Reactor) reactor vessel with a DVI(Direct Vessel Injection) injection mode is presented based on the experimental observations in the MIDAS (Multi-dimensional Investigation in Downcomer Annulus Simulation) steam-water facility. From the steady-state tests to similate a late reflood phase of LBLOCA (Large Break Loss-of-Coolant Accidents), major thermal-hydraulic phenomena in the downcomer are quantified under a wide range of test conditions. Especially, isothermal lines show well multi-dimensional phenomena of phase interaction between steam and water in the annulus downcomer. Overall test results show that multi-dimensional thermal-hydraulic behaviors occur in the downcomer annulus region as expected. The MIDAS test facility is a steam-water separate effect test facility, which is 1/4.93 linearly scaled-down of a 1400 MWe PWR type of nuclear reactor, with focusing on understanding multi-dimensional thermal-hydraulic phenomena in annulus downcomer with various types of safety injection location during refill or reflood phase of a LBLOCA in PWR

  12. Man-Machine Integration Design and Analysis System (MIDAS) v5: Augmentations, Motivations, and Directions for Aeronautics Applications

    Science.gov (United States)

    Gore, Brian F.

    2011-01-01

    As automation and advanced technologies are introduced into transport systems ranging from the Next Generation Air Transportation System termed NextGen, to the advanced surface transportation systems as exemplified by the Intelligent Transportations Systems, to future systems designed for space exploration, there is an increased need to validly predict how the future systems will be vulnerable to error given the demands imposed by the assistive technologies. One formalized approach to study the impact of assistive technologies on the human operator in a safe and non-obtrusive manner is through the use of human performance models (HPMs). HPMs play an integral role when complex human-system designs are proposed, developed, and tested. One HPM tool termed the Man-machine Integration Design and Analysis System (MIDAS) is a NASA Ames Research Center HPM software tool that has been applied to predict human-system performance in various domains since 1986. MIDAS is a dynamic, integrated HPM and simulation environment that facilitates the design, visualization, and computational evaluation of complex man-machine system concepts in simulated operational environments. The paper will discuss a range of aviation specific applications including an approach used to model human error for NASA s Aviation Safety Program, and what-if analyses to evaluate flight deck technologies for NextGen operations. This chapter will culminate by raising two challenges for the field of predictive HPMs for complex human-system designs that evaluate assistive technologies: that of (1) model transparency and (2) model validation.

  13. Meat quality of lambs fed silk flower hay (Calotropis procera SW in the diet Qualidade de carne de cordeiros alimentados com feno de flor-de-seda (Calotropis procera SW na dieta

    Directory of Open Access Journals (Sweden)

    Roberto Germano Costa

    2011-06-01

    Full Text Available The objective of this work was to evaluate the influence of using silk flower hay replacing corn and soybean meal on physical-chemical and sensorial traits of lamb meat. It was used 32 intact Morada Nova male lambs (12.7 ± 2 kg initial body weigth on feedlot system, distributed in a completely randomized design with four levels (0, 15, 30 and 45% on dry matter basis. The use of silk flower hay in the diet influenced quality of meat and carcass, leg weight, tissue composition, moisture, juiciness and flavor. Replacing corn (26.67% and soybean (3.33% with silk flower hay does not affect the tissue composition, ratios and muscularity index of leg and physical-chemical parameters of semimembranosus muscle of Morada Nova lambs.Objetivou-se avaliar a influência do uso de feno de flor-de-seda em substituição ao milho e ao farelo de soja nas características físico-químicas e sensoriais da carne de cordeiros. Utilizaram-se 32 cordeiros Morada Nova, machos não-castrados (12,7 ± 2 kg de peso vivo inicial, em confinamento, distribuídos em delineamento inteiramente ao acaso com quatro níveis (0, 15, 30 e 45% com base na MS. A utilização de feno de flor-de-seda na dieta influenciou a qualidade da carcaça e da carne, o peso da perna, a composição tecidual, a umidade, a suculência e o sabor. A substituição do milho (26,67% e da soja (3,33% pelo feno de flor-de-seda não altera composição tecidual, relação e índice de muscularidade da perna e os parâmetros físico-químicos do músculo semimembranosus de cordeiros Morada Nova.

  14. A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen

    Directory of Open Access Journals (Sweden)

    Michael N Dawson

    2016-12-01

    and geography for decades into the future. But golden ages come and go, and they need not touch every domain in a discipline nor affect subdisciplines at the same time; moreover, what appears to be a Golden Age may sometimes have an undesirable ‘Midas touch’. Contexts within and outwith biogeography—e.g., methods, knowledge, climate, biodiversity, politics—are continually changing, and at times it can be challenging to establish or maintain relevance. In so many races with the Red Queen, we suggest that biogeography will enjoy greatest success if we also increasingly engage with the epistemology of our discipline.

  15. Analgesia e sedação durante a instalação do cateter central de inserção periférica em neonatos

    OpenAIRE

    Costa,Priscila; Bueno,Mariana; Oliva,Cintia Luiza; Castro,Talita Elci de; Camargo,Patrícia Ponce de; Kimura,Amélia Fumiko

    2013-01-01

    Objetivou-se caracterizar as estratégias de analgesia e sedação em neonatos submetidos à instalação do cateter central de inserção periférica (CCIP) e relacioná-las ao número de punções venosas, duração do procedimento e posicionamento da ponta do cateter. Estudo transversal com coleta prospectiva de dados, realizado em uma unidade de cuidados intensivos neonatais de um hospital privado na cidade de São Paulo, no período de 31 de agosto de 2010 a 01 de julho de 2011, em que foram avaliadas 25...

  16. A Validated Set of MIDAS V5 Task Network Model Scenarios to Evaluate Nextgen Closely Spaced Parallel Operations Concepts

    Science.gov (United States)

    Gore, Brian Francis; Hooey, Becky Lee; Haan, Nancy; Socash, Connie; Mahlstedt, Eric; Foyle, David C.

    2013-01-01

    The Closely Spaced Parallel Operations (CSPO) scenario is a complex, human performance model scenario that tested alternate operator roles and responsibilities to a series of off-nominal operations on approach and landing (see Gore, Hooey, Mahlstedt, Foyle, 2013). The model links together the procedures, equipment, crewstation, and external environment to produce predictions of operator performance in response to Next Generation system designs, like those expected in the National Airspaces NextGen concepts. The task analysis that is contained in the present report comes from the task analysis window in the MIDAS software. These tasks link definitions and states for equipment components, environmental features as well as operational contexts. The current task analysis culminated in 3300 tasks that included over 1000 Subject Matter Expert (SME)-vetted, re-usable procedural sets for three critical phases of flight; the Descent, Approach, and Land procedural sets (see Gore et al., 2011 for a description of the development of the tasks included in the model; Gore, Hooey, Mahlstedt, Foyle, 2013 for a description of the model, and its results; Hooey, Gore, Mahlstedt, Foyle, 2013 for a description of the guidelines that were generated from the models results; Gore, Hooey, Foyle, 2012 for a description of the models implementation and its settings). The rollout, after landing checks, taxi to gate and arrive at gate illustrated in Figure 1 were not used in the approach and divert scenarios exercised. The other networks in Figure 1 set up appropriate context settings for the flight deck.The current report presents the models task decomposition from the tophighest level and decomposes it to finer-grained levels. The first task that is completed by the model is to set all of the initial settings for the scenario runs included in the model (network 75 in Figure 1). This initialization process also resets the CAD graphic files contained with MIDAS, as well as the embedded

  17. Fully automated rodent brain MR image processing pipeline on a Midas server: from acquired images to region-based statistics.

    Science.gov (United States)

    Budin, Francois; Hoogstoel, Marion; Reynolds, Patrick; Grauer, Michael; O'Leary-Moore, Shonagh K; Oguz, Ipek

    2013-01-01

    Magnetic resonance imaging (MRI) of rodent brains enables study of the development and the integrity of the brain under certain conditions (alcohol, drugs etc.). However, these images are difficult to analyze for biomedical researchers with limited image processing experience. In this paper we present an image processing pipeline running on a Midas server, a web-based data storage system. It is composed of the following steps: rigid registration, skull-stripping, average computation, average parcellation, parcellation propagation to individual subjects, and computation of region-based statistics on each image. The pipeline is easy to configure and requires very little image processing knowledge. We present results obtained by processing a data set using this pipeline and demonstrate how this pipeline can be used to find differences between populations.

  18. "BSR Eagle" lendas Tartusse

    Index Scriptorium Estoniae

    2005-01-01

    8. veebr. Tartus Loodusuurijate Seltsi majas toimunud seminarist "Mida Juku õues ei õpi, seda Juhan vallaametnikuna ei tea", mis toimus Läänemere-piirkonna loodusharidusprojekti "BSR Eagle" raames

  19. Teaduslikustunud poliitika ja avalik arvamus / Jürgen Habermas ; tõlk. Andres Luure

    Index Scriptorium Estoniae

    Habermas, Jürgen

    2002-01-01

    Poliitika teaduslikustamine ei ole praegusel ajal veel tõsiasi, küll aga tendents, mida asjade seis aimata lubab: eelkõige iseloomustavad seda riigitellimusliku uurimistöö maht ning teadusliku nõustamise ulatus avalikes teenistustes

  20. Kriisi fataalne oht / Ulrich Beck

    Index Scriptorium Estoniae

    Beck, Ulrich

    2009-01-01

    Sotsioloogi arvates peitub praeguses majanduskriisis võimalus tuua Euroopa Liit uutele alustele, võttes aluseks printsiibi, et poliitika on rahvuslikul tasemel seda edukam, mida euroopalikum, kosmopoliitlikum ta on

  1. Can a Point-of-Care Troponin I Assay be as Good as a Central Laboratory Assay? A MIDAS Investigation.

    Science.gov (United States)

    Peacock, W Frank; Diercks, Deborah; Birkhahn, Robert; Singer, Adam J; Hollander, Judd E; Nowak, Richard; Safdar, Basmah; Miller, Chadwick D; Peberdy, Mary; Counselman, Francis; Chandra, Abhinav; Kosowsky, Joshua; Neuenschwander, James; Schrock, Jon; Lee-Lewandrowski, Elizabeth; Arnold, William; Nagurney, John

    2016-09-01

    We aimed to compare the diagnostic accuracy of the Alere Triage Cardio3 Tropinin I (TnI) assay (Alere, Inc., USA) and the PathFast cTnI-II (Mitsubishi Chemical Medience Corporation, Japan) against the central laboratory assay Singulex Erenna TnI assay (Singulex, USA). Using the Markers in the Diagnosis of Acute Coronary Syndromes (MIDAS) study population, we evaluated the ability of three different assays to identify patients with acute myocardial infarction (AMI). The MIDAS dataset, described elsewhere, is a prospective multicenter dataset of emergency department (ED) patients with suspected acute coronary syndrome (ACS) and a planned objective myocardial perfusion evaluation. Myocardial infarction (MI) was diagnosed by central adjudication. The C-statistic with 95% confidence intervals (CI) for diagnosing MI by using a common population (n=241) was 0.95 (0.91-0.99), 0.95 (0.91-0.99), and 0.93 (0.89-0.97) for the Triage, Singulex, and PathFast assays, respectively. Of samples with detectable troponin, the absolute values had high Pearson (R(P)) and Spearman (R(S)) correlations and were R(P)=0.94 and R(S)=0.94 for Triage vs Singulex, R(P)=0.93 and R(S)=0.85 for Triage vs PathFast, and R(P)=0.89 and R(S)=0.73 for PathFast vs Singulex. In a single comparative population of ED patients with suspected ACS, the Triage Cardio3 TnI, PathFast, and Singulex TnI assays provided similar diagnostic performance for MI.

  2. Kunstihoones saab vastutustundlikult vahetuskaupa teha / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Tutvustatakse Andrea Creutzi kunstiprojekti "Varjatud ressursivoog", mis on osa Tallinna Kunstihoones eksponeeritavast näitusest "Kapital (See veab meid alt)". Näitus tegeleb alternatiivsete majandusmudelitega

  3. Kunstnik kavatseb maalidest jaanitule teha / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2005-01-01

    Andrus Older teeb jaanitule oma piltidest, mis jäävad ostmata oksjonil, mille ta korraldab päev enne Sillamäe lähedal Orava talus. Harrastuskunstnik paneb müüki umbes 50 maali. Kunstniku kommentaarid

  4. Magnum ihkas teha apteekide suurketti / Kadi Heinsalu

    Index Scriptorium Estoniae

    Heinsalu, Kadi, 1966-

    2008-01-01

    Eesti suurimaid apteegiketi omanikke ja ravimite hulgimüüjaid Magnum tahtis koonduda apteegiketiga Farmacia, millega ta oleks saanud suurimaks apteekide haldajaks Eestis. Vt. samas: Võrdlus: apteeke rohkem kolme suurema kaubamärgi all

  5. Development and performance evaluation of 32-channel gamma densitometer for the measurement of flow pattern and void fraction in the downcomer of MIDAS test facility

    International Nuclear Information System (INIS)

    Chu, In Cheol; Kim, Y. K.; Yun, B. J.; Kwon, T. S.; Euh, D. J.; Song, C.

    2002-03-01

    APR 1400, which adopts DVI type of ECCS, is expected to show its unique thermal hydraulic phenomena. Therefore, it is necessary to investigate whether existing safety analysis code can correctly predict the thermal hydraulic phenomena. Among the several phenomena, void fraction and flow pattern govern the other major phenomena. Therefore, the main objective of the present study is to develop the 32-channel gamma densitometer which can measure the void fraction and flow pattern in the downcomer at various locations. The 32-channel gamma densitometer for MIDAS test apparatus has been developed. Throughout the performance evaluation test, the integrity of the 32 channel gamma densitometer has been validated. The measurement error of water film thickness is expected to be less than ±0.5mm. Also, it can correctly predict the flow patterns and the transition location of flow pattern in the downcomer of MIDAS test apparatus

  6. O uso de dexmedetomidina na sedação de crises hipercianóticas em um recém-nascido com tetralogia de Fallot Sedation of hypercyanotic spells in a neonate with tetralogy of Fallot using dexmedetomidine

    Directory of Open Access Journals (Sweden)

    Hideaki Senzaki

    2008-08-01

    Full Text Available OBJETIVO: A sedação é um passo importante para aliviar e prevenir a recorrência de cianose no manejo de pacientes com crises hipercianóticas associadas à tetralogia de Fallot (T4F. Este relato de caso ilustra a eficácia da sedação induzida por dexmedetomidina no manejo de crises hipercianóticas em um recém-nascido com T4F. DESCRIÇÃO: Um paciente recém-nascido a termo de 8 dias de idade com T4F apresentava crises hipercianóticas, indicadas por quedas abruptas no nível de saturação arterial (SpO2, medido por um oxímetro de pulso, de 80% até 50%, quando o paciente ficava agitado ou irritável. Nós começamos a infusão contínua de dexmedetomidina em uma dosagem de 0,2 µg/kg/min sem injeção de ataque em bolus. Cerca de meia hora depois do início da infusão de dexmedetomidina, o paciente atingiu um nível aceitável de sedação, e sua freqüência cardíaca diminuiu aproximadamente 20 batidas por minuto. Não houve nenhuma depressão respiratória aparente ou mudança acentuada em sua pressão arterial. A SpO2 também continuou estável durante a infusão de dexmedetomidina. No dia seguinte à sua hospitalização, o paciente passou com sucesso por uma operação de anastomose de Blalock-Taussig. COMENTÁRIOS: A dexmedetomidina pode ser útil no manejo de crises hipercianóticas em pacientes pediátricos com T4F.OBJECTIVE:Sedation is an important step in the management of patients with hypercyanotic spells associated with tetralogy of Fallot (TOF to ameliorate and prevent recurrence of cyanosis. This case report illustrates the effectiveness of dexmedetomidine-induced sedation in the management of hypercyanotic spells in a neonate with TOF. DESCRIPTION: An 8-day-old term newborn patient with TOF showed hypercyanotic spells, as indicated by an abrupt decrease in arterial saturation (SpO2 level measured by a pulse oximeter from 80% to as low as 50%, when the patient became irritable and agitated. We started continuous

  7. Efeito de extratos aquosos de estruturas de grama-seda no desenvolvimento inicial de plântulas de arroz, milho e trigo Effects of aqueous extracts of bermudagrass structures on initial growth of rice, corn and wheat seedlings

    Directory of Open Access Journals (Sweden)

    Maria do Carmo de Salvo Soares Novo

    2009-09-01

    Full Text Available Objetivou-se verificar os efeitos de extratos aquosos de estruturas de grama-seda (Cynodon dactylon (L. Pers e de exsudatos radiculares presentes no solo no qual a planta se desenvolveu, sobre a germinação e o crescimento inicial de arroz, trigo e milho. O extrato aquoso das estruturas da parte aérea, subterrâneas e da planta inteira, assim como do estolão, da folha + colmo, estolão + folha + colmo, rizoma, raiz e de rizoma + raiz de grama-seda foi elaborado a partir de 100 g L-1 de material seco. Foram avaliados a protrusão da radícula e os crescimentos da radícula e da plúmula de cada espécie. A inibição ou o estímulo do desenvolvimento inicial de plântulas foi dependente da espécie avaliada e da estrutura vegetal empregada na elaboração do extrato. A protrusão da radícula foi mais inibida que os crescimentos da radícula e da plúmula. O estímulo do desenvolvimento da radícula e da plúmula foi mais evidente quando o extrato foi elaborado a partir das estruturas do sistema radicular, da parte aérea e da planta inteira que de estruturas individualizadas de grama-seda. De modo geral, o arroz e o milho foram mais inibidos por extratos elaborados a partir da parte aérea e subterrânea, respectivamente. Para o trigo, a inibição ou o estímulo foi dependente da variável analisada. O desenvolvimento da radícula e da plúmula de arroz, milho e trigo foi estimulado por extrato elaborado a partir da planta inteira. O extrato produzido a partir da fração argila + silte estimulou o desenvolvimento da radícula do milho e da plúmula do trigo.The objective of this work was to study the effects of aqueous extracts of Bermudagrass structures (Cynodon dactylon (L. Pers and soil exudates, on the germination and initial growth of rice, corn and wheat seedlings. The aqueous extracts of above-ground and subterranean parts and of the whole plant, as well as of stolons, leaves + culm, stolons + leaves + culm, rhizome, root and rhizome

  8. A randomized, controlled, crossover trial of oral midazolam and hydroxyzine for pediatric dental sedation Sedação com midazolam e hidroxizina por via oral em Odontopediatria: ensaio clínico randomizado, controlado e cruzado

    Directory of Open Access Journals (Sweden)

    Alessandra Rodrigues de Almeida Lima

    2003-09-01

    Full Text Available The effectiveness of oral midazolam in pediatric dentistry is controversial. This randomized, controlled, crossover, double blind clinical trial was conducted in order to study the effect of midazolam, used either alone or in association with hydroxyzine, during child dental treatment. Thirty seven dental sedation sessions were carried out on 11 ASA I uncooperative children less than five years-old. In each appointment children were randomly assigned to groups: P - placebo, M - midazolam (1.0 mg/kg, or MH - midazolam (0.75 mg/kg plus hydroxyzine (2.0 mg/kg. Vital signs (blood pressure, breathing rate, pulse and oxygen saturation and behavior parameters (consciousness, crying, movement, overall behavior were evaluated every 15 minutes. Friedman and Wilcoxon statistical tests were used to compare groups and different moments in the same group. Normal values of vital signs were usually registered. Heart rate increased in groups P and M as the session went on. Group M presented less crying and movement at the first 15 minutes of treatment. Group MH caused more drowsiness at the beginning of the session. Overall behavior was better in group M than in groups P or MH. Group M produced effective sedation in 77% of the cases, and group MH did so in 30.8%. It was concluded that midazolam was effective and safe, and its association with hydroxyzine did not lead to additional advantages in pediatric dental sedation.Há controvérsias quanto aos benefícios do midazolam na sedação de crianças durante a atenção odontológica. Conduziu-se um ensaio clínico controlado, cruzado e duplo-cego para comparar o efeito sedativo em Odontopediatria da administração oral do midazolam, associado ou não à hidroxizina. Trinta e sete sessões foram realizadas em 11 crianças menores de cinco anos, ASA I. Em cada atendimento, os pacientes receberam aleatoriamente o medicamento conforme os grupos: P - placebo, M - midazolam (1,0 mg/kg; MH - midazolam (0,75 mg

  9. Performance of MIDAS Over East African Longitude Sector: Case Study During 4-14 March 2012 Quiet to Disturbed Geomagnetic Conditions

    Science.gov (United States)

    Giday, Nigussie M.; Katamzi-Joseph, Zama T.

    2018-02-01

    This study investigates the performance of a tomographic algorithm, Multi-Instrument and Data Analysis System (MIDAS), during an extended period of 4-14 March 2012, containing moderate and strong geomagnetic storms conditions, over an understudied and data scarce Eastern African longitude sector. Nonetheless, a relatively better distribution of Global Navigation Satellite Systems stations exists along a narrow longitude sector between 30°E and 44°E and latitude range of 30°S and 36°N that spans the equatorial, middle-, and low-latitude ionosphere. Then results are compared with independent global models such as International Reference Ionosphere 2012 (IRI-2012) and global ionosphere map (GIM). MIDAS performance was better than that of the IRI-2012 and GIM models in terms of capturing the diurnal trends as well as the short temporal total electron content (TEC) structures, with least root-mean-square errors (RMSEs). Overall, MIDAS results showed better agreement with the observation vertical TEC (VTEC) with computed maximum correlation coefficient (r) of 0.99 and minimum root-mean-square error (RMSE) of 2.91 TEC unit (1 TECU = 1,016 el m-2 over all the test stations and the validation days. Conversely, for the IRI-2012 and GIM TEC estimates, the corresponding maximum computed r values were 0.93 and 0.99, respectively, while the minimum RMSEs were 13.03 TECU and 6.52 TECU, respectively, for all the test stations and the validation days.

  10. Jalakäijad aetakse ju alla / Leo Kunnas

    Index Scriptorium Estoniae

    Kunnas, Leo, 1967-

    2009-01-01

    Autori sõnul on ainus argument, millega idanaabri sõjalist juhtkonda veenda, sõjaaja relvajõud. Selleks on vaja tõestada, et suudame need vajaduse korral mobiliseerida, seda aga on võimalik teha suurõppuste korraldamisega

  11. Estonija ne privlekatelna dlja zarubezhnõhh investorov / Kirill Smirnov

    Index Scriptorium Estoniae

    Smirnov, Kirill

    2007-01-01

    Mäos avati ehituslike kuivsegude tehas Sakret OÜ. Läti investeeringu tähtsusest, Eesti ja Läti majandussuhetest ja koostööst. Tehase rajamisel arvestati eelkõige ekspordiga ida turule, kuid Venemaa ja Eesti pingestatud suhted võivad seda olulisel mõjutada

  12. Kuidas finantseerida eksporditehinguid / Andrus Treier

    Index Scriptorium Estoniae

    Treier, Andrus, 1974-

    2005-01-01

    Enamik riike pakub oma ettevõtetele otseseid või kaudseid toetusi ekspordi edendamiseks. Lisaks sellele soovitab KredEx-i juhataja ettevõtetel teha ekspordikindlustus, millega erakindlustaja või riiklik ekspordikrediidiasutus kindlustab ettevõttele raha laekumise tehingu eest ka juhul, kui ostja teatud põhjusel seda ei tee. Lisa: Riikliku ekspordigarantii eelised

  13. Raha varjatud hind / Peter Singer

    Index Scriptorium Estoniae

    Singer, Peter

    2008-01-01

    Kathleen Vohs, Nicole Mead ja Miranda Goode leidsid eksperimentide kaudu viisi, kuidas panna inimesed mõtlema rahast, ilma et neil seda otseselt teha kästaks. Rahast mõtlema suunatud katsealuste grupi käitumine erines suuresti teise grupi käitumisest

  14. Stable coordination of the inhibitory Ca2+ ion at MIDAS in integrin CD11b/CD18 by an antibody-derived ligand aspartate: Implications for integrin regulation and structure-based drug design

    Science.gov (United States)

    Mahalingam, Bhuvaneshwari; Ajroud, Kaouther; Alonso, Jose Luis; Anand, Saurabh; Adair, Brian; Horenstein, Alberto L; Malavasi, Fabio; Xiong, Jian-Ping; Arnaout, M. Amin

    2011-01-01

    A central feature of integrin interaction with physiologic ligands is the monodentate binding of a ligand carboxylate to a Mg2+ ion hexacoordinated at the metal-ion-dependent-adhesion site (MIDAS) in the integrin A-domain. This interaction stabilizes the A-domain in the high-affinity state, which is distinguished from the default low-affinity state by tertiary changes in the domain that culminate in cell adhesion. Small molecule ligand-mimetic integrin antagonists act as partial agonists, eliciting similar activating conformational changes in the A-domain, which has contributed to paradoxical adhesion and increased patient mortality in large clinical trials. As with other ligand-mimetic integrin antagonists, the function-blocking monoclonal antibody (mAb) 107 binds MIDAS of integrin CD11b/CD18 A-domain (CD11bA), but in contrast, it favors the inhibitory Ca2+ ion over Mg2+ at MIDAS. We determined the crystal structures of the Fab fragment of mAb 107 complexed to the low- and high-affinity states of CD11bA. Favored binding of Ca2+ at MIDAS is caused by the unusual symmetric bidentate ligation of a Fab-derived ligand Asp to a heptacoordinated MIDAS Ca2+. Binding of Fab 107 to CD11bA did not trigger the activating tertiary changes in the domain or in the full-length integrin. These data show that denticity of the ligand Asp/Glu can modify divalent cation selectivity at MIDAS and hence integrin function. Stabilizing the Ca2+ ion at MIDAS by bidentate ligation to a ligand Asp/Glu may provide one approach for designing pure integrin antagonists. PMID:22095715

  15. The role of rare morph advantage and conspicuousness in the stable gold-dark colour polymorphism of a crater lake Midas cichlid fish.

    Science.gov (United States)

    Torres-Dowdall, Julián; Golcher-Benavides, Jimena; Machado-Schiaffino, Gonzalo; Meyer, Axel

    2017-09-01

    Genetically based stable colour polymorphisms provide a unique opportunity to study the evolutionary processes that preserve genetic variability in the wild. Different mechanisms are proposed to promote the stability of polymorphisms, but only few empirical examples have been documented, resulting in an incomplete understanding of these mechanisms. A remarkable genetically determined stable colour polymorphism is found in the Nicaraguan Midas cichlid species complex (Amphilophus cf. citrinellus). All Midas cichlids start their life with a dark-grey coloration (dark morph), but individuals carrying the dominant "gold" allele (c. 10%) lose their melanophores later in life, revealing the underlying orange coloration (gold morph). How this polymorphism is maintained remains unclear. Two main hypotheses have been proposed, both suggesting differential predation upon colour morphs as the proximate mechanism. One predicts that the conspicuous gold morph is more likely to be preyed upon, but this disadvantage is balanced by their competitive dominance over the dark morph. The second hypothesis suggests a rare morph advantage where the rarer gold morph experiences less predation. Empirical evidence for either of these mechanisms is still circumstantial and inconclusive. We conducted two field experiments in a Nicaraguan crater lake using wax models simulating both morphs to determine predation pressure upon Midas cichlid colour morphs. First, we tested the interaction of coloration and depth on attack rate. Second, we tested the interaction of fish size and coloration. We contrasted the pattern of attacks from these experiments to the predicted predation patterns from the hypotheses proposed to explain the colour polymorphism's stability. Large models imitating colour morphs were attacked at similar rates irrespectively of their position in the water column. Yet, attacks upon small models resembling juveniles were directed mainly towards dark models. This resulted in a

  16. Species-specific differences in adaptive phenotypic plasticity in an ecologically relevant trophic trait: hypertrophic lips in Midas cichlid fishes.

    Science.gov (United States)

    Machado-Schiaffino, Gonzalo; Henning, Frederico; Meyer, Axel

    2014-07-01

    The spectacular species richness of cichlids and their diversity in morphology, coloration, and behavior have made them an ideal model for the study of speciation and adaptive evolution. Hypertrophic lips evolved repeatedly and independently in African and Neotropical cichlid radiations. Cichlids with hypertrophic lips forage predominantly in rocky crevices and it has been hypothesized that mechanical stress caused by friction could result in larger lips through phenotypic plasticity. To test the influence of the environment on the size and development of lips, we conducted a series of breeding and feeding experiments on Midas cichlids. Full-sibs of Amphilophus labiatus (thick-lipped) and Amphilophus citrinellus (thin-lipped) each were split into a control group which was fed food from the water column and a treatment group whose food was fixed to substrates. We found strong evidence for phenotypic plasticity on lip area in the thick-lipped species, but not in the thin-lipped species. Intermediate phenotypic values were observed in hybrids from thick- and thin-lipped species reared under "control" conditions. Thus, both a genetic, but also a phenotypic plastic component is involved in the development of hypertrophic lips in Neotropical cichlids. Moreover, species-specific adaptive phenotypic plasticity was found, suggesting that plasticity is selected for in recent thick-lipped species. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  17. Growth supported by fiscal policy / Kalle Kukk

    Index Scriptorium Estoniae

    Kukk, Kalle

    2006-01-01

    Mida läbipaistvam, tõhusam ja konservatiivsem on eelarvepoliitika, seda soodsamalt mõjub see majandusele, sh majanduskasvule. Eelarvetasakaal, valitsussektori kogukulud ja maksukoormus on kolm olulist konservatiivsuse eelarveindikaatorit. Esitatakse ülevaade selle kohta, mida seni on tehtud majanduskasvu ning eelarvedefitsiidi, valitsussektori kulude ja maksukoormuse omavaheliste mõjude valdkonnas. Metodoloogia, järeldused

  18. Genetic, comparative genomic, and expression analyses of the Mc1r locus in the polychromatic Midas cichlid fish (Teleostei, Cichlidae Amphilophus sp.) species group.

    Science.gov (United States)

    Henning, Frederico; Renz, Adina Josepha; Fukamachi, Shoji; Meyer, Axel

    2010-05-01

    Natural populations of the Midas cichlid species in several different crater lakes in Nicaragua exhibit a conspicuous color polymorphism. Most individuals are dark and the remaining have a gold coloration. The color morphs mate assortatively and sympatric population differentiation has been shown based on neutral molecular data. We investigated the color polymorphism using segregation analysis and a candidate gene approach. The segregation patterns observed in a mapping cross between a gold and a dark individual were consistent with a single dominant gene as a cause of the gold phenotype. This suggests that a simple genetic architecture underlies some of the speciation events in the Midas cichlids. We compared the expression levels of several candidate color genes Mc1r, Ednrb1, Slc45a2, and Tfap1a between the color morphs. Mc1r was found to be up regulated in the gold morph. Given its widespread association in color evolution and role on melanin synthesis, the Mc1r locus was further investigated using sequences derived from a genomic library. Comparative analysis revealed conserved synteny in relation to the majority of teleosts and highlighted several previously unidentified conserved non-coding elements (CNEs) in the upstream and downstream regions in the vicinity of Mc1r. The identification of the CNEs regions allowed the comparison of sequences from gold and dark specimens of natural populations. No polymorphisms were found between in the population sample and Mc1r showed no linkage to the gold phenotype in the mapping cross, demonstrating that it is not causally related to the color polymorphism in the Midas cichlid.

  19. Report of the investigation of the accident at the MIDAS MYTH/MILAGRO Trailer Park on Rainier Mesa at Nevada Test Site on February 15, 1984

    International Nuclear Information System (INIS)

    1984-01-01

    Fourteen persons were injured, one fatally, when the ground upon which they were working collapsed, forming a subsidence crater in the recording trailer park of the MIDAS MYTH/MILAGRO nuclear weapons effects test on Rainier Mesa at the US Department of Energy's Nevada Test Site on February 15, 1984. Those persons injured were contractor and laboratory employees from Reynolds Electrical and Engineering Co., Inc. (REECo), Pan American World Services, Inc. (PANAM), and the Los Alamos National Laboratory (LANL). This report presents the results of an investigation into the causes, effects, and response to the accident. 42 figures

  20. Ablação curativa da fibrilação atrial: comparação entre sedação profunda e anestesia geral Curative ablation of atrial fibrillation: comparison between deep sedation and general anesthesia

    Directory of Open Access Journals (Sweden)

    Elizabeth Bessadas Penna Firme

    2012-12-01

    Full Text Available OBJETIVO: Comparar sedação profunda com anestesia geral para ablação curativa de fibrilação atrial. MÉTODOS: Estudo prospectivo, aleatório, com 32 pacientes, idades entre 18 e 65 anos, ASA 2 e 3, IMC d" 30kg/m², distribuídos em dois grupos: sedação profunda (G1 e anestesia geral (G2. Todos receberam midazolan (0,5mg/kg venoso. O G1 recebeu propofol (1mg/kg e máscara facial de O2, seguido da infusão contínua de propofol (25-50mg/kg/min e remifentanil (0,01-0,05µg/kg/min. O G2 recebeu propofol (2mg/kg e máscara laríngea com tubo de drenagem, seguido da infusão contínua de propofol (60-100mg/kg/min e remifentanil (0,06-0,1µg/kg/min. Foram comparados: frequência cardíaca, pressão arterial invasiva, complicações, recidiva (desfecho em três meses e gasometrias. RESULTADOS: Os pacientes do G1 apresentaram gasometrias arteriais com níveis de PaCO2 maiores e pH menores (p=0,001 e maior incidência de tosse. Ocorreu diminuição da PAM e FC no G2. Exceto a tosse, as complicações e recidivas foram semelhantes em ambos os grupos. CONCLUSÃO: Ambas as técnicas podem ser utilizadas para a ablação curativa da fibrilação atrial. A anestesia geral proporcionou menores alterações respiratórias e maior imobilidade do paciente.OBJECTIVE: To compare deep sedation with general anesthesia for curative ablation of atrial fibrillation. METHODS: We conducted a prospective, randomized study with 32 patients, aged between 18 and 65 years, ASA 2 and 3, BMI d" 30kg/m2, divided into two groups: deep sedation (G1 and general anesthesia (G2. All patients received intravenous midazolam (0.5 mg / kg. G1 received propofol (1mg/kg and O2 by facemask, followed by continuous infusion of propofol (25-50mg/kg/min and remifentanil (0.01-0.05 mg / kg / min. G2 received propofol (2mg/kg and laryngeal mask with built-in drain tube, followed by continuous infusion of propofol (60-100mg/kg/min and remifentanil (0.06 to 0.1g/kg/min. We compared heart rate

  1. Calcified aquatic insect larval constructions in the Pleistocene tufa of Jebel El Mida, Gafsa, southern Tunisia: Recognition and paleoenvironmental significance

    Science.gov (United States)

    Ben Ahmed, Walid; Henchiri, Mohsen; Mastouri, Amna; Slim S'himi, Najet

    2018-04-01

    Calcified aquatic larval cases were recognized and identified in the Pleistocene tufa masses of Jebel El Mida, Gafsa, southern Tunisia. These larval constructions belong to three main insect families: caddisflies (Trichoptera, Hydropsychidae), midges (Diptera, Chironomidae) and aquatic moths (Lepidoptera, Pyralidae) that inhabited tubes in the tufa and spun nets. Each insect community has its distinctive characteristics of larval constructions that allow their recognition. The larval constructions recognized comprise fixed and portable (for caddisflies) dwelling cases and silken retreats and feeding capture nets. These last-mentioned are almost completely eroded and only remnants are preserved. The spatial distribution of these larval cases within the tufa is not random but, rather imposed by some specific paleohydraulic conditions. It's the reason why aquatic insect larval constructions are considered as prominent tool for the reconstruction of tufa and travertine depositional environments. Chironomid fixed dwelling cases (diameters range from 0.6 mm for clustered tubes to 3 mm) indicate the deposition of tufa under lotic (flowing) or lentic (standing) water conditions. The later hydraulic condition is shared with hydropsychids with fixed retreats (0.2-4 mm in diameter). Portable case-building caddisflies (case length ranging from 5 to 20 mm, and diameter from 3 to 5 mm at the cephalic end) prefer lentic conditions and are almost completely missing in high-energy flowing water locations that are preferred by pyralids (tubes are between 5 and 10 mm long and 3 mm in diameter). These insect families benefit from inhabiting the tufa by the availability of construction materials of their cases and the necessary space for their development.

  2. The View from the Trees: Nocturnal Bull Ants, Myrmecia midas, Use the Surrounding Panorama While Descending from Trees.

    Science.gov (United States)

    Freas, Cody A; Wystrach, Antione; Narendra, Ajay; Cheng, Ken

    2018-01-01

    Solitary foraging ants commonly use visual cues from their environment for navigation. Foragers are known to store visual scenes from the surrounding panorama for later guidance to known resources and to return successfully back to the nest. Several ant species travel not only on the ground, but also climb trees to locate resources. The navigational information that guides animals back home during their descent, while their body is perpendicular to the ground, is largely unknown. Here, we investigate in a nocturnal ant, Myrmecia midas , whether foragers travelling down a tree use visual information to return home. These ants establish nests at the base of a tree on which they forage and in addition, they also forage on nearby trees. We collected foragers and placed them on the trunk of the nest tree or a foraging tree in multiple compass directions. Regardless of the displacement location, upon release ants immediately moved to the side of the trunk facing the nest during their descent. When ants were released on non-foraging trees near the nest, displaced foragers again travelled around the tree to the side facing the nest. All the displaced foragers reached the correct side of the tree well before reaching the ground. However, when the terrestrial cues around the tree were blocked, foragers were unable to orient correctly, suggesting that the surrounding panorama is critical to successful orientation on the tree. Through analysis of panoramic pictures, we show that views acquired at the base of the foraging tree nest can provide reliable nest-ward orientation up to 1.75 m above the ground. We discuss, how animals descending from trees compare their current scene to a memorised scene and report on the similarities in visually guided behaviour while navigating on the ground and descending from trees.

  3. The View from the Trees: Nocturnal Bull Ants, Myrmecia midas, Use the Surrounding Panorama While Descending from Trees

    Directory of Open Access Journals (Sweden)

    Cody A. Freas

    2018-01-01

    Full Text Available Solitary foraging ants commonly use visual cues from their environment for navigation. Foragers are known to store visual scenes from the surrounding panorama for later guidance to known resources and to return successfully back to the nest. Several ant species travel not only on the ground, but also climb trees to locate resources. The navigational information that guides animals back home during their descent, while their body is perpendicular to the ground, is largely unknown. Here, we investigate in a nocturnal ant, Myrmecia midas, whether foragers travelling down a tree use visual information to return home. These ants establish nests at the base of a tree on which they forage and in addition, they also forage on nearby trees. We collected foragers and placed them on the trunk of the nest tree or a foraging tree in multiple compass directions. Regardless of the displacement location, upon release ants immediately moved to the side of the trunk facing the nest during their descent. When ants were released on non-foraging trees near the nest, displaced foragers again travelled around the tree to the side facing the nest. All the displaced foragers reached the correct side of the tree well before reaching the ground. However, when the terrestrial cues around the tree were blocked, foragers were unable to orient correctly, suggesting that the surrounding panorama is critical to successful orientation on the tree. Through analysis of panoramic pictures, we show that views acquired at the base of the foraging tree nest can provide reliable nest-ward orientation up to 1.75 m above the ground. We discuss, how animals descending from trees compare their current scene to a memorised scene and report on the similarities in visually guided behaviour while navigating on the ground and descending from trees.

  4. CRESCIMENTO, DESENVOLVIMENTO E PRODUTIVIDADE DO GERGELIM BRS SEDA IRRIGADO COM ÁGUA DO LENÇOL FREÁTICO, NA AGROVILA DE CANUDOS, EM CEARÁ MIRIM(RN

    Directory of Open Access Journals (Sweden)

    José Américo Grilo

    2013-05-01

    Full Text Available A cultura do gergelim, hoje pouco difundida no Brasil, pode torna-se uma alternativa para a produção de grãos por pequenos e médios produtores rurais do Nordeste brasileiro, por ser o gergelim considerado um alimento funcional e apresentar boas perspectivas de mercado. O experimento de campo foi conduzido na Agrovila de Canudos, pertencente ao município de Ceará-Mirim (RN, distante 23 km do centro da cidade. A área plantada foi de 0,7 ha, irrigado com água do lençol freático, utilizando 80.000 plantas da cultivar BRS Seda. O presente trabalho objetivou avaliar o crescimento e o desenvolvimento vegetativo dessa cultivar, tendo em vista que esses parâmetros são indicadores de produtividade, além de ser uma fonte de informação para implantação da cultura na Agrovila e, a inclusão nos meios produtivos daquela comunidade. Ao final do ciclo produtivo, o gergelim apresentou, em média, 95,70 cápsulas e 20,40 g de grãos por planta. Esses valores estão correlacionados à produtividade dos grãos, que correspondeu a 1.600 kg/ha. O resultado indica que essa cultivar de gergelim pode ser inserida nos meios produtivos desse município e, por conseguinte, da região, podendo garantir uma fonte alternativa de renda para as famílias dos pequenos produtores.

  5. MiDAS 2.0: an ecosystem-specific taxonomy and online database for the organisms of wastewater treatment systems expanded for anaerobic digester groups.

    Science.gov (United States)

    McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca; Nierychlo, Marta; Kristensen, Jannie Munk; Karst, Søren Michael; Albertsen, Mads; Nielsen, Per Halkjær

    2017-01-01

    Wastewater is increasingly viewed as a resource, with anaerobic digester technology being routinely implemented for biogas production. Characterising the microbial communities involved in wastewater treatment facilities and their anaerobic digesters is considered key to their optimal design and operation. Amplicon sequencing of the 16S rRNA gene allows high-throughput monitoring of these systems. The MiDAS field guide is a public resource providing amplicon sequencing protocols and an ecosystem-specific taxonomic database optimized for use with wastewater treatment facility samples. The curated taxonomy endeavours to provide a genus-level-classification for abundant phylotypes and the online field guide links this identity to published information regarding their ecology, function and distribution. This article describes the expansion of the database resources to cover the organisms of the anaerobic digester systems fed primary sludge and surplus activated sludge. The updated database includes descriptions of the abundant genus-level-taxa in influent wastewater, activated sludge and anaerobic digesters. Abundance information is also included to allow assessment of the role of emigration in the ecology of each phylotype. MiDAS is intended as a collaborative resource for the progression of research into the ecology of wastewater treatment, by providing a public repository for knowledge that is accessible to all interested in these biotechnologically important systems. http://www.midasfieldguide.org. © The Author(s) 2017. Published by Oxford University Press.

  6. Branching of the PIF3 regulatory network in Arabidopsis: roles of PIF3-regulated MIDAs in seedling development in the dark and in response to light.

    Science.gov (United States)

    Sentandreu, Maria; Leivar, Pablo; Martín, Guiomar; Monte, Elena

    2012-04-01

    Plants need to accurately adjust their development after germination in the underground darkness to ensure survival of the seedling, both in the dark and in the light upon reaching the soil surface. Recent studies have established that the photoreceptors phytochromes and the bHLH phytochrome interacting factors PIFs regulate seedling development to adjust it to the prevailing light environment during post-germinative growth. However, complete understanding of the downstream regulatory network implementing these developmental responses is still lacking. In a recent work, published in The Plant Cell, we report a subset of PIF3-regulated genes in dark-grown seedlings that we have named MIDAs (MISREGULATED IN DARK). Analysis of their functional relevance using mutants showed that four of them present phenotypic alterations in the dark, and that each affected a particular facet of seedling development, suggesting organ-specific branching in the signal that PIF3 relays downstream. Furthermore, our results also showed an altered response to light in seedlings with an impaired PIF3/MIDA regulatory network, indicating that these factors might also be essential to initiate and optimize the developmental adjustment of the seedling to the light environment.

  7. Enhanced gravity-wave activity and interhemispheric coupling during the MaCWAVE/MIDAS northern summer program 2002

    Directory of Open Access Journals (Sweden)

    E. Becker

    2006-07-01

    Full Text Available We present new sensitivity experiments that link observed anomalies of the mesosphere and lower thermosphere at high latitudes during the MaCWAVE/MIDAS summer program 2002 to enhanced planetary Rossby-wave activity in the austral winter troposphere.

    We employ the same general concept of a GCM having simplified representations of radiative and latent heating as in a previous study by Becker et al. (2004. In the present version, however, the model includes no gravity wave (GW parameterization. Instead we employ a high vertical and a moderate horizontal resolution in order to describe GW effects explicitly. This is supported by advanced, nonlinear momentum diffusion schemes that allow for a self-consistent generation of inertia and mid-frequency GWs in the lower atmosphere, their vertical propagation into the mesosphere and lower thermosphere, and their subsequent dissipation which is induced by prescribed horizontal and vertical mixing lengths as functions of height.

    The main anomalies in northern summer 2002 consist of higher temperatures than usual above 82 km, an anomalous eastward mean zonal wind between 70 and 90 km, an altered meridional flow, enhanced turbulent dissipation below 80 km, and enhanced temperature variations associated with GWs. These signals are all reasonably described by differences between two long-integration perpetual model runs, one with normal July conditions, and another run with modified latent heating in the tropics and Southern Hemisphere to mimic conditions that correspond to the unusual austral winter 2002. The model response to the enhanced winter hemisphere Rossby-wave activity has resulted in both an interhemispheric coupling through a downward shift of the GW-driven branch of the residual circulation and an increased GW activity at high summer latitudes. Thus a quantitative explanation of the dynamical state of the northern mesosphere and lower

  8. Sampling genetic diversity in the sympatrically and allopatrically speciating Midas cichlid species complex over a 16 year time series

    Directory of Open Access Journals (Sweden)

    Bunje Paul ME

    2007-02-01

    Full Text Available Abstract Background Speciation often occurs in complex or uncertain temporal and spatial contexts. Processes such as reinforcement, allopatric divergence, and assortative mating can proceed at different rates and with different strengths as populations diverge. The Central American Midas cichlid fish species complex is an important case study for understanding the processes of speciation. Previous analyses have demonstrated that allopatric processes led to species formation among the lakes of Nicaragua as well as sympatric speciation that is occurring within at least one crater lake. However, since speciation is an ongoing process and sampling genetic diversity of such lineages can be biased by collection scheme or random factors, it is important to evaluate the robustness of conclusions drawn on individual time samples. Results In order to assess the validity and reliability of inferences based on different genetic samples, we have analyzed fish from several lakes in Nicaragua sampled at three different times over 16 years. In addition, this time series allows us to analyze the population genetic changes that have occurred between lakes, where allopatric speciation has operated, as well as between different species within lakes, some of which have originated by sympatric speciation. Focusing on commonly used genetic markers, we have analyzed both DNA sequences from the complete mitochondrial control region as well as nuclear DNA variation at ten microsatellite loci from these populations, sampled thrice in a 16 year time period, to develop a robust estimate of the population genetic history of these diversifying lineages. Conclusion The conclusions from previous work are well supported by our comprehensive analysis. In particular, we find that the genetic diversity of derived crater lake populations is lower than that of the source population regardless of when and how each population was sampled. Furthermore, changes in various estimates of

  9. Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

    Science.gov (United States)

    Zhu, Jieqing; Choi, Won-Seok; McCoy, Joshua G; Negri, Ana; Zhu, Jianghai; Naini, Sarasija; Li, Jihong; Shen, Min; Huang, Wenwei; Bougie, Daniel; Rasmussen, Mark; Aster, Richard; Thomas, Craig J; Filizola, Marta; Springer, Timothy A; Coller, Barry S

    2012-03-14

    An integrin found on platelets, α(IIb)β(3) mediates platelet aggregation, and α(IIb)β(3) antagonists are effective antithrombotic agents in the clinic. Ligands bind to integrins in part by coordinating a magnesium ion (Mg(2+)) located in the β subunit metal ion-dependent adhesion site (MIDAS). Drugs patterned on the integrin ligand sequence Arg-Gly-Asp have a basic moiety that binds the α(IIb) subunit and a carboxyl group that coordinates the MIDAS Mg(2+) in the β(3) subunits. They induce conformational changes in the β(3) subunit that may have negative consequences such as exposing previously hidden epitopes and inducing the active conformation of the receptor. We recently reported an inhibitor of α(IIb)β(3) (RUC-1) that binds exclusively to the α(IIb) subunit; here, we report the structure-based design and synthesis of RUC-2, a RUC-1 derivative with a ~100-fold higher affinity. RUC-2 does not induce major conformational changes in β(3) as judged by monoclonal antibody binding, light scattering, gel chromatography, electron microscopy, and a receptor priming assay. X-ray crystallography of the RUC-2-α(IIb)β(3) headpiece complex in 1 mM calcium ion (Ca(2+))/5 mM Mg(2+) at 2.6 Å revealed that RUC-2 binds to α(IIb) the way RUC-1 does, but in addition, it binds to the β(3) MIDAS residue glutamic acid 220, thus displacing Mg(2+) from the MIDAS. When the Mg(2+) concentration was increased to 20 mM, however, Mg(2+) was identified in the MIDAS and RUC-2 was absent. RUC-2's ability to inhibit ligand binding and platelet aggregation was diminished by increasing the Mg(2+) concentration. Thus, RUC-2 inhibits ligand binding by a mechanism different from that of all other α(IIb)β(3) antagonists and may offer advantages as a therapeutic agent.

  10. Alusetu rikastumise sätete kohaldamisest pärimislepingu korral / Urve Liin

    Index Scriptorium Estoniae

    Liin, Urve, 1952-

    2005-01-01

    Asjaoludest kahe kaasuse näitel, miks pärimislepinguga soodustatud isikud ei suutnud kohtus oma seadusest tulenevat õigust maksma panna ja mida nad oleksid võinud teisiti teha. Probleemide analüüsimisel on võrdlusena kasutatud Saksa õiguskirjanduses välja toodud seisukohti

  11. "Sel kevadel olen ma eriti ilus..." : [luuletused] / Triin Soomets

    Index Scriptorium Estoniae

    Soomets, Triin

    2003-01-01

    Sisu: "Sel kevadel olen ma eriti ilus..." ; "Tahaksin teha midagi tõelist; midagi suurt..." ; "veebruaris on keha nii valge et syda läheb pahaks..." ; "kõige kohutavamad lepingud..." ; "Igal loojangul kutsun sind ja igal koidikul tõukan su ära..." ; "need hakid..." ; "Põhja vajudes on viimane asi, mida ma näen, rohelised sähvatused..."

  12. Moeuudised

    Index Scriptorium Estoniae

    1998-01-01

    Prantsuse moemaja Chloe peadisainer Stella McCartney aitas loomakaitseorganisatsioonil PETA teha dokumentaalfilmi, milles paljastatakse karusloomafarmide telgitaguseid. Chloe supelkostüümist, mida soovitatakse eeskujuks võtta endale bikiinide heegeldamisel. Yves Saint Laurenti moemaja korraldab gigantse moeshow jalgpallistaadionil, kus algab jalgpalli MM. Yves Saint Laurent on kavandanud MMi korraldajate-asjameeste kostüümid

  13. Läbirääkijate viis lemmikviga / Max H. Bazerman, Don A Moore

    Index Scriptorium Estoniae

    Bazerman, Max H.

    2008-01-01

    Harvardi Ärikooli professorid annavad nõu, mida teha siis, kui jäädakse läbirääkimistel liigselt pidama esimese pakkumise külge, ollakse jäärapäine, minnakse liiale enesekindlusega või keskendutakse liiga kitsale eesmärgile

  14. Sprashivajem? Otvetshajem... / Vladimir Evve

    Index Scriptorium Estoniae

    Evve, Vladimir

    2002-01-01

    Autor kommenteerib Res Publica reklaamartiklit kohalikeks valimisteks, kus esitati kaks küsimust - mida teha, et me elaksime nagu inimesed ja kes on süüdi, et Kohtla-Järvel on halb? Vt. ka 20. sep. Infopressi

  15. Pigem klaas kihisevat kui Ferrari / Sathnam Sanghera ; tõlk. Erik Aru

    Index Scriptorium Estoniae

    Sanghera, Sathnam

    2005-01-01

    Autor kirjeldab oma kohtumist Ferrari peatestisõitja Dario Benuzziga ja GlaxoSmithKline'i mustsõstrajoogi Ribena maitsja Isobel Hoare'iga ning järeldab, et võib teha tööga rahulolu olemusest järeldusi, mida eksperdid ei näi märkavat

  16. 21. sajandi õpetajast ikka veel tulevikuvaates / Sirje Pärismaa ; kommenteerinud Margit Timakov ja Kristi Mikiver

    Index Scriptorium Estoniae

    Pärismaa, Sirje, 1958-

    2015-01-01

    Maailma parima haridusega riikide viiendal tippkohtumisel Kanadas Banffis jõuti kõnelustega 21. sajandi klassiruumi: arutleti õpetajate liidrirolli, koostöö ja innovatsiooni üle ning küsiti, mida teha teisiti, et ühiskond õpetajat senisest rohkem väärtustaks

  17. Miks nahk sügeleb

    Index Scriptorium Estoniae

    2008-01-01

    Briti teadlaste rühm koos kolleegidega Brasiiliast, Lõuna-Aafrika Vabariigist ja Jaapanist uurisid nahahaigust, mille puhul sügelus on väga sage - perekondlikku primaarset naha amüloidoosi. Lisa: Mida saab sügeluse vastu kodus teha

  18. Vihula otsib oma teed. Tagamõisa lugu 1990-1998 / Leila Pärtelpoeg

    Index Scriptorium Estoniae

    Pärtelpoeg, Leila, 1927-

    1998-01-01

    Vihula tagamõisast, mida asuti taastama skandinaavia stiilis. 18. sajandil ehitatud hoone ennistustegevust asus juhtima AS 'Vihula'. Sisekujundaja Leila Pärtelpoeg. Eesmärgiks oli valmis teha hotell arvestamata 'tärnidiktaati'. Naeruväärse tasu eest tehti, mis suudeti. Olukorra muutumisest uue omaniku tulekul. Mantelkorstna põues oleva ruumi seinamaalingud ئ Järvi Kotkas.

  19. Minu isiklik poliitvang / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2006-01-01

    Ilmunud ka: Infopress 18. aug. nr. 33 lk. 152-153. Valgevenes on elementaarse inimõiguse kasutamise eest vangi mõistetud kodanikuühenduse Partnerstva üks liidreid Mikalai Astrejka. Autori sõnul on vähim, mida meie teha saame, toetusallkirjade andmine Valgevene poliitvangide vabastamiseks

  20. Vanaduse garantii / Evelin Int-Lambot

    Index Scriptorium Estoniae

    Int-Lambot, Evelin, 1968-

    2005-01-01

    Olukorras, kus umbes 20% Eesti lastest elab vaesuses ja igal aastal lisandub ligi 1200 vanemliku hoolitsuseta last, ei tohiks kurta ideepuuduse üle, mida teha EL-i ja NATO-sse saamise järel. Eesmärk peaks olema, et ükski laps ei elaks vaesuses

  1. India hiilgav viletsus / Andrei Hvostov

    Index Scriptorium Estoniae

    Hvostov, Andrei, 1963-

    2006-01-01

    Hiinat nimetatakse maailma töökojaks, Indiat aga bürooks (back office), võrdlus põhineb India IT-firmade edul - kõik tegevused, mida saab teha arvutite abil, kipuvad kolima Indiasse. Tulevikuriik India on hädas keskaegsete tavadega

  2. Director murrab pead : Kui sul on haamer, siis meenutavad kõik asjad naelu / Anni Hartikainen

    Index Scriptorium Estoniae

    Hartikainen, Anni

    2008-01-01

    Mida teha, kui ettevõtte on langenud rutiini ning edasiminekuks oleks vaja kollektiivset ärkamist. Küsimusele otsivad vastust Ragn-Sells AS ärijuht Agu Remmelg. Siin ongi vaja kollektiivset obadust! ja Nixor Eesti AS arendusspetsialist Toomas Arula. Õppimise võlu ja valu

  3. Rootsi kindral hõivaks sõja korral Eesti saared / Jukka Rislakki

    Index Scriptorium Estoniae

    Rislakki, Jukka

    2011-01-01

    Rootsi sõjateaduste akadeemia väljaandes "Till bröders hjälp. Med sikte på en svensk solidarisk strategi" arutlevad eksperdid, mida Rootsi ja Soome võiksid teha ja peaksid tegema, kui Venemaa ründab Balti riike

  4. Eesti Maaülikooli uus üliõpilasesindus astus ametisse / Silver Kuusik

    Index Scriptorium Estoniae

    Kuusik, Silver

    2008-01-01

    Maaülikooli üliõpilasesinduse üldistest ja konkreetsetest eesmärkidest. Küsimusele, mida vast valitud esinduse liikmed kooli heaks teha saavad, vastasid Kersti Pärtelpoeg, Veikko Kiis, Anni Haavakats, Julia Koltsova, Maarja Sõrmus, Rainer Zirnask, Gerlin Järvela, Iiris Rausk, Marili Köster, Christina Birnbaum ja Siim Lokko

  5. Paja-katla mäng finaali eel / Deivil Tserp

    Index Scriptorium Estoniae

    Tserp, Deivil, 1968-

    2005-01-01

    Autor kritiseerib Eesti suuremate erakondade juhtide valimiseelset debatti 12. oktoobril Eesti Televisiooni eetris olnud "Valimisstuudio" saates, kus poliitikud püüdsid paljastada üksteise tumedaid tegusid selle asemel, et selgitada valijatele, mida nende erakondadel on kavas tulevikus teha eestimaalaste hüvanguks

  6. Küsimuste tulv automaksu teel / Villem Tori

    Index Scriptorium Estoniae

    Tori, Villem

    2008-01-01

    Eesti Autoettevõtete Liidu direktor Villem Tori imestab sotsiaaldemokraatide automaksu idee üle, sest kordagi pole öeldud, mida sellest maksust laekuva rahaga teha soovitakse. Vt. samas: Võimalik automaks. Kommenteerivad võimlemisklubi Janika juht Janika Mölder ja suusatreener Mati Alaver

  7. Kas see kõik oli hirmus viga? / Edward Lucas

    Index Scriptorium Estoniae

    Lucas, Edward, 1962-

    2009-01-01

    Autor vaatab tagasi Eestis toimunud reformidele ning avaldab arvamust, mida oleks võinud teha teisiti. Suurimaks läbikukkumiseks nimetab ta kinnisvaramulli kiiret kasvu ja suutmatust rakendada konservatiivsemat rahapoliitikat, kuid märgib, et Eesti on end okupatsioonivaremetest hämmastavalt kiiresti üles ehitanud

  8. Ühe saarma lugu / Silja Kana ; kommenteerinud Val Rajasaar, Teet Koitjärv

    Index Scriptorium Estoniae

    Kana, Silja

    2012-01-01

    Mida teha kui juhtute otsa sõitma jahiulukile, I või II kategooria kaitsealusele liigile. Lugu saarmast, kes hukkus kokkupõrkel autoga, kuid kellest tänu teadlikele inimestele valmib topis-õppevahend Keskkonnaameti tellitud komplektis Valgamaale

  9. Lenin Hitleriga vähemalt võrdseks / Ken-Marti Vaher

    Index Scriptorium Estoniae

    Vaher, Ken-Marti, 1974-

    2008-01-01

    Riigikogu õiguskomisjoni esimees käsitleb ühiste väärtuste kehtestamist euroopalikus kultuuriruumis, mis tähendab muu hulgas hinnangut inimvaenulikele ideoloogiatele. Autor pakub välja kolm sammu, mida saaks Eestis ära teha muutmaks läänemaailma senist suhtumist kommunismi

  10. Kivid sinu sees / Marika Makarova

    Index Scriptorium Estoniae

    Makarova, Marika

    2011-01-01

    Sapi- ja neerukivide tekke põhjustest, ravist nii tavameditsiini kui ka Steineri poolt loodud antroposoofilise meditsiini vahenditega ning mida saab teha, et kividest hoiduda. Nõuannavad Ida-Tallinna Keskhaigla kirurgid Rein Lumiste ja Toomas Tamm ning perearstikeskuse Medicum perearst Pille Soone

  11. A hybrid genetic linkage map of two ecologically and morphologically divergent Midas cichlid fishes (Amphilophus spp.) obtained by massively parallel DNA sequencing (ddRADSeq).

    Science.gov (United States)

    Recknagel, Hans; Elmer, Kathryn R; Meyer, Axel

    2013-01-01

    Cichlid fishes are an excellent model system for studying speciation and the formation of adaptive radiations because of their tremendous species richness and astonishing phenotypic diversity. Most research has focused on African rift lake fishes, although Neotropical cichlid species display much variability as well. Almost one dozen species of the Midas cichlid species complex (Amphilophus spp.) have been described so far and have formed repeated adaptive radiations in several Nicaraguan crater lakes. Here we apply double-digest restriction-site associated DNA sequencing to obtain a high-density linkage map of an interspecific cross between the benthic Amphilophus astorquii and the limnetic Amphilophus zaliosus, which are sympatric species endemic to Crater Lake Apoyo, Nicaragua. A total of 755 RAD markers were genotyped in 343 F(2) hybrids. The map resolved 25 linkage groups and spans a total distance of 1427 cM with an average marker spacing distance of 1.95 cM, almost matching the total number of chromosomes (n = 24) in these species. Regions of segregation distortion were identified in five linkage groups. Based on the pedigree of parents to F(2) offspring, we calculated a genome-wide mutation rate of 6.6 × 10(-8) mutations per nucleotide per generation. This genetic map will facilitate the mapping of ecomorphologically relevant adaptive traits in the repeated phenotypes that evolved within the Midas cichlid lineage and, as the first linkage map of a Neotropical cichlid, facilitate comparative genomic analyses between African cichlids, Neotropical cichlids and other teleost fishes.

  12. Sedação e analgesia em crianças: uma abordagem prática para as situações mais freqüentes Analgesia and sedation in children: practical approach for the most frequent situations

    OpenAIRE

    Santiago Mencía Bartolomé; Jesús López-Herce Cid; Norberto Freddi

    2007-01-01

    OBJETIVOS: Revisar as indicações, doses e formas de administração dos sedativos, analgésicos e relaxantes musculares mais utilizados na criança, bem como os métodos de monitorização da sedação. FONTES DOS DADOS: Levantamento bibliográfico utilizando a base de dados MEDLINE e revisão da experiência em nossas unidades de cuidados intensivos pediátricos. SÍNTESE DOS DADOS: A administração contínua de drogas analgésicas e sedativas impede o aparecimento das fases de subsedação e requer menor assi...

  13. MiDAS I (mild Decompression Alternative to Open Surgery): a preliminary report of a prospective, multi-center clinical study.

    Science.gov (United States)

    Chopko, Bohdan; Caraway, David L

    2010-01-01

    Neurogenic claudication due to lumbar spinal stenosis is a common problem that can be caused by many factors including hypertrophic ligamentum flavum, facet hypertrophy, and disc protrusion. When standard medical therapies such as pain medication, epidural steroid injections, and physical therapy fail, or when the patient is unwilling, unable, or not severe enough to advance to more invasive surgical procedures, both physicians and patients are often left with a treatment dilemma. Patients in this study were treated with mild, an ultra-minimally invasive lumbar decompression procedure using a dorsal approach. The mild procedure is performed under fluoroscopic imaging to resect bone adjacent to, and achieve partial resection of, the hypertrophic ligamentum flavum with minimal disruption of surrounding muscular and skeletal structure. To assess the clinical application and patient safety and functional outcomes of the mild lumbar decompression procedure in the treatment of symptomatic central canal spinal stenosis. Multi-center, non-blinded, prospective clinical study. Fourteen US spine specialist practices. Between July 2008 and January 2010, 78 patients were enrolled in the MiDAS I Study and treated with the mild procedure for lumbar decompression. Of these patients, 6-week follow-up was available for 75 patients. Visual Analog Score (VAS), Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ), and SF-12v2 Health Survey. Outcomes were assessed at baseline and 6 weeks post-treatment. There were no major device or procedure-related complications reported in this patient cohort. At 6 weeks, the MiDAS I Study showed statistically and clinically significant reduction of pain as measured by VAS, ZCQ, and SF-12v2. In addition, improvement in physical function and mobility as measured by ODI, ZCQ, and SF-12v2 was statistically and clinically significant in this study. This is a preliminary report encompassing 6-week follow-up. There was no control group

  14. Pool kuningriiki mängujuhi eest! / Sash Uusjärv

    Index Scriptorium Estoniae

    Uusjärv, Sash

    2007-01-01

    D&D ehk rollimängust. Sõna võtavad rollimängijad, lisaks sõnaseletusi ja "Tuntud mängijad maailmas". Rollimängijad arutavad : "Miks võiks iga inimene kas või korra elus D&D proovida?" ja "...ja miks ta seda teha ei tohiks?". Rollimängu Eestisse jõudmise teed meenutab Asko Künnap artiklis "Asko Künnapi kommentaar"

  15. Rootsi otsib endiselt tundmatut objekti / Liisa Tagel

    Index Scriptorium Estoniae

    Tagel, Liisa

    2014-01-01

    Stockholmi saarestikus toimuvast Rootsi kaitseväe luureoperatsioonist, mille eesmärk on koguda infot võõrriigi allveetegevuse kohta. Võimalikku Vene allveelaeva märgati Rootsi vetes 17. oktoobril. Eestil puuduvad vahendid veealuse tegevuse jälgimiseks, seda suudetakse teha ainult koostöös NATO partneritega. Ahto Lobjakase arvamusartikkel Euroopa julgeolekupoliitilisest situatsioonist seoses Rootsi sündmustega, lk. 14

  16. Transcriptome-Wide Single Nucleotide Polymorphisms (SNPs for Abalone (Haliotis midae: Validation and Application Using GoldenGate Medium-Throughput Genotyping Assays

    Directory of Open Access Journals (Sweden)

    Rouvay Roodt-Wilding

    2013-09-01

    Full Text Available Haliotis midae is one of the most valuable commercial abalone species in the world, but is highly vulnerable, due to exploitation, habitat destruction and predation. In order to preserve wild and cultured stocks, genetic management and improvement of the species has become crucial. Fundamental to this is the availability and employment of molecular markers, such as microsatellites and Single Nucleotide Polymorphisms (SNPs . Transcriptome sequences generated through sequencing-by-synthesis technology were utilized for the in vitro and in silico identification of 505 putative SNPs from a total of 316 selected contigs. A subset of 234 SNPs were further validated and characterized in wild and cultured abalone using two Illumina GoldenGate genotyping assays. Combined with VeraCode technology, this genotyping platform yielded a 65%−69% conversion rate (percentage polymorphic markers with a global genotyping success rate of 76%−85% and provided a viable means for validating SNP markers in a non-model species. The utility of 31 of the validated SNPs in population structure analysis was confirmed, while a large number of SNPs (174 were shown to be informative and are, thus, good candidates for linkage map construction. The non-synonymous SNPs (50 located in coding regions of genes that showed similarities with known proteins will also be useful for genetic applications, such as the marker-assisted selection of genes of relevance to abalone aquaculture.

  17. Transcriptome-wide single nucleotide polymorphisms (SNPs) for abalone (Haliotis midae): validation and application using GoldenGate medium-throughput genotyping assays.

    Science.gov (United States)

    Bester-Van Der Merwe, Aletta; Blaauw, Sonja; Du Plessis, Jana; Roodt-Wilding, Rouvay

    2013-09-23

    Haliotis midae is one of the most valuable commercial abalone species in the world, but is highly vulnerable, due to exploitation, habitat destruction and predation. In order to preserve wild and cultured stocks, genetic management and improvement of the species has become crucial. Fundamental to this is the availability and employment of molecular markers, such as microsatellites and single nucleotide (SNPs). Transcriptome sequences generated through sequencing-by-synthesis technology were utilized for the in vitro and in silico identification of 505 putative SNPs from a total of 316 selected contigs. A subset of 234 SNPs were further validated and characterized in wild and cultured abalone using two Illumina GoldenGate genotyping assays. Combined with VeraCode technology, this genotyping platform yielded a 65%-69% conversion rate (percentage polymorphic markers) with a global genotyping success rate of 76%-85% and provided a viable means for validating SNP markers in a non-model species. The utility of 31 of the validated SNPs in population structure analysis was confirmed, while a large number of SNPs (174) were shown to be informative and are, thus, good candidates for linkage map construction. The non-synonymous SNPs (50) located in coding regions of genes that showed similarities with known proteins will also be useful for genetic applications, such as the marker-assisted selection of genes of relevance to abalone aquaculture.

  18. Turbulent energy dissipation rates observed by Doppler MST Radar and by rocket-borne instruments during the MIDAS/MaCWAVE campaign 2002

    Directory of Open Access Journals (Sweden)

    N. Engler

    2005-06-01

    Full Text Available During the MIDAS/MaCWAVE campaign in summer 2002 we have observed turbulence using Doppler beam steering measurements obtained from the ALWIN VHF radar at Andøya/Northern Norway. This radar was operated in the Doppler beam steering mode for turbulence investigations during the campaign, as well as in spaced antenna mode, for continuously measuring the background wind field. The real-time data analysis of the Doppler radar backscattering provided the launch conditions for the sounding rockets. The spectral width data observed during the occurrence of PMSE were corrected for beam and shear broadening caused by the background wind field to obtain the turbulent part of the spectral width. The turbulent energy dissipation rates determined from the turbulent spectral width vary between 5 and 100mW kg-1 in the altitude range of 80-92km and increase with altitude. These estimations agree well with the in-situ measurements using the CONE sensor which was launched on 3 sounding rockets during the campaign.

  19. Inter-Hemispheric Coupling During Recent North Polar Summer Periods as Predicted by MaCWAVE/MIDAS Rocket Data and Traced by TIMED/SABER Measurements

    Science.gov (United States)

    Goldberg, Richard A.; Feofilov, Artem G.; Kutepov, Alexander A.; Pesnell W. Dean; Schmidlin, Francis J.

    2011-01-01

    In July, 2002, the MaCWAVE-MIDAS Rocket Program was launched from Andoya Rocket Range (ARR) in Norway. Data from these flights demonstrated that the polar summer mesosphere during this period was unusual, at least above ARR. Theoretical studies have since been published that imply that the abnormal characteristics of this polar summer were generated by dynamical processes occurring in the southern polar winter hemisphere. We have used data from the SABER instrument aboard the NASA Thermosphere Ionosphere Mesosphere Energetics and Dynamics (TIMED) Satellite to study these characteristics and compare them with the features observed in the ensuing eight years. For background, the TIMED Satellite was launched on December 7,2001 to study the dynamics and energy of the mesosphere and lower thermosphere. The SABER instrument is a limb scanning infrared radiometer designed to measure temperature of the region as well as a large number of minor constituents. In this study, we review the MaCWAVE rocket results. Next, we investigate the temperature characteristics of the polar mesosphere as a function of spatial and temporal considerations. We have used the most recent SABER dataset (1.07). Weekly averages are used to make comparisons between the winter and summer hemispheres. Furthermore, the data analysis agrees with recent theoretical studies showing that this behavior is a result of anomalous dynamical events in the southern hemisphere. The findings discussed here clearly show the value of scientific rocket flights used in a discovery mode.

  20. Evaluation of de novo assembly technique in the South African abalone Haliotis midae transcriptome: A comparison from Illumina and 454 systems

    Directory of Open Access Journals (Sweden)

    Barbara Picone

    2016-12-01

    Full Text Available Next generation sequencing platforms have recently been used to rapidly characterize transcriptome sequences from a number of non-model organisms. The present study compares two of the most frequently used platforms, the Roche 454-pyrosequencing and the Illumina sequencing-by-synthesis (SBS, on the same RNA sample obtained from an intertidal gastropod mollusc species, Haliotis midae. All the sequencing reads were deposited in the Short Read Archive (SRA database are retrievable under the accession number [SRR071314 (Illumina Genome Analyzer II] and [SRR1737738, SRR1737737, SRR1737735, SRR1737734 (454 GS FLX] in the SRA database of NCBI. Three transcriptomes, composed of either pure 454 or Illumina reads or a mixture of read types (Hybrid, were assembled using CLC Genomics Workbench software. Illumina assemblies performed the best de novo transcriptome characterization in terms of contig length, whereas the 454 assemblies tended to improve the complete assembly of gene transcripts. Both the Hybrid and Illumina assemblies produced longer contigs covering more of the transcriptome than 454 assemblies. However, the addition of 454 significantly increased the number of genes annotated.

  1. Wikileaks kinnitas NATO otsust teha Baltimaadele kaitsekavad / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2010-01-01

    Wikileaksi avalikustatud saladokumentidest sai teatavaks, et NATO kiitis heaks varem Poola kaitseks mõeldud Eagle Guardiani nimelise plaani laiendamise Eestile, Lätile ja Leedule. NATO ja Venemaa reageeringutest

  2. Ma ei taha teha poliitpropagandat / Joanna Rajkowska ; interv. Ave Randviir

    Index Scriptorium Estoniae

    Rajkowska, Joanna

    2008-01-01

    21.-23. veebruarini 2008 Tallinnas Okupatsioonide Muuseumis toimunud "Public Preparation'i" sarja rahvusvahelisest seminarist أTranslocal Express. Jubilee Editionؤ, mis vaatles kaasaegse kunsti ning üha süvenevate natsionalistlike meeleolude suhet Euroopa idapiiril. Esinejate hulgas ka Eleonore de Montesquiou, Flo Kasearu ja Maria-Kristiina Soomre. Joanna Rajkowska projektist Varssavi kesklinnas "Tervitused Jeruusalemma avenüült".

  3. Kuidas Hiinas raha teha / Jaanus Hämarsoo

    Index Scriptorium Estoniae

    Hämarsoo, Jaanus

    2004-01-01

    Tallinna Sadama juhatuse endine aseesimees, firma Worldwide Invest nõukogu esimees Jaan Toots meenutab reisi Hiinasse, kohtumisi Hiina ärimeestega. Eesti aukonsulite Hongkongis ja Macaus võõrustamisest Eestis

  4. Afganistan - teha tuleb rohkem / Jaap de Hoop Scheffer

    Index Scriptorium Estoniae

    de Hoop Scheffer, Jaap, 1948-

    2006-01-01

    NATO peasekretäri sõnul on G-8 tippkohtumisel üheks tähtsamaks probleemiks Afganistani probleemide arutamine. Autor rõhutab rahvusvahelise koostöö tähtsust takistamaks ebademokraatliku režiimi taaskehtestamist Afganistanis

  5. Kuidas kõrgemale ohvitserile ettekannet teha / James Stavridis

    Index Scriptorium Estoniae

    Stavridis, James, 1955-

    2013-01-01

    Endine NATO Euroopa liitlasvägede ülemjuhataja jagab nõuandeid mõjusa ja konstruktiivse ettekande kirjutamiseks ja selle esitlemiseks. Lisatud foto, kus kujutatud James Stavridise autasustamist president Toomas Hendrik Ilvese poolt

  6. Innovatsioon võib firmas imet teha / Mariliis Pinn

    Index Scriptorium Estoniae

    Pinn, Mariliis

    2008-01-01

    Statistikaameti korraldatud innovatsiooniuuringust selgus, et innovaatiliste ettevõtete käive kasvas 2004-2006. aastal 47%, mitteinnovaatiliste firmade 22% vastu. Diagramm: Uuenduslike ettevõtete osatähtsus

  7. President Ilves : Eesti tuleb teha ahvatlevaks elukeskkonna, mitte maksukeskkonnana

    Index Scriptorium Estoniae

    2007-01-01

    13. augustil 2007 kogunes Paslepas Presidendi Mõttekoda, mis seekord keskendus teaduse, majanduse ja innovatsiooni küsimustele. President Toomas Hendrik Ilves rõhutas vajadust investeerida senisest rohkem arendusse, teadusesse ja laiemalt haridusse, et vähendada vahemaad Euroopa jõukamate riikidega. Ingl. k. ilmunud ka: Vaba Eesti Sõna 16. aug. 2007, lk. 12, pealk.: President Ilves: Estonia must be made into an attractive living environment, not a tax environment

  8. Eestis asub Euroopa Liidus ainulaadne nanotehnoloogiliste filtrite tehas / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2006-01-01

    Eesti nn. varjatud meisterfirmad Esfil Tehno, AS Regio. Varjatud meistri mõiste. Lisa: Varjatud meistrite iseloomujooned. Tabelid. Lisad: Zamperia toodab Disney jaoks. Autodesk pakub aistingut kõigi meelte tarvis

  9. Parsing parallel evolution: ecological divergence and differential gene expression in the adaptive radiations of thick-lipped Midas cichlid fishes from Nicaragua.

    Science.gov (United States)

    Manousaki, Tereza; Hull, Pincelli M; Kusche, Henrik; Machado-Schiaffino, Gonzalo; Franchini, Paolo; Harrod, Chris; Elmer, Kathryn R; Meyer, Axel

    2013-02-01

    The study of parallel evolution facilitates the discovery of common rules of diversification. Here, we examine the repeated evolution of thick lips in Midas cichlid fishes (the Amphilophus citrinellus species complex)-from two Great Lakes and two crater lakes in Nicaragua-to assess whether similar changes in ecology, phenotypic trophic traits and gene expression accompany parallel trait evolution. Using next-generation sequencing technology, we characterize transcriptome-wide differential gene expression in the lips of wild-caught sympatric thick- and thin-lipped cichlids from all four instances of repeated thick-lip evolution. Six genes (apolipoprotein D, myelin-associated glycoprotein precursor, four-and-a-half LIM domain protein 2, calpain-9, GTPase IMAP family member 8-like and one hypothetical protein) are significantly underexpressed in the thick-lipped morph across all four lakes. However, other aspects of lips' gene expression in sympatric morphs differ in a lake-specific pattern, including the magnitude of differentially expressed genes (97-510). Generally, fewer genes are differentially expressed among morphs in the younger crater lakes than in those from the older Great Lakes. Body shape, lower pharyngeal jaw size and shape, and stable isotopes (δ(13)C and δ(15)N) differ between all sympatric morphs, with the greatest differentiation in the Great Lake Nicaragua. Some ecological traits evolve in parallel (those related to foraging ecology; e.g. lip size, body and head shape) but others, somewhat surprisingly, do not (those related to diet and food processing; e.g. jaw size and shape, stable isotopes). Taken together, this case of parallelism among thick- and thin-lipped cichlids shows a mosaic pattern of parallel and nonparallel evolution. © 2012 Blackwell Publishing Ltd.

  10. The effect of saline coolant on temperature levels during decortication with a Midas Rex: An in vitro model using sheep cervical vertebrae.

    Directory of Open Access Journals (Sweden)

    Asher eLivingston

    2015-07-01

    Full Text Available Decortication of bone with a high speed burr in the absence of coolant may lead to local thermal necrosis and decreased healing ability which may negatively impact clinical outcome. Little data is available on the impact of applying a coolant during the burring process. This study aims to establish an in vitro model to quantitatively assess peak temperatures during endplate preparation with a high speed burr.Six sheep cervical vertebrae were dissected and mounted. Both end plates were used to give a total of 12 sites. Two thermocouples were inserted into each vertebra, 2mm below the end plate surface and a thermal-camera set up to measure surface temperature. A high speed burr (Midas Rex, Medtronic, Fort Worth, TX was used to decorticate the bone in a side to side sweeping pattern, using a matchstick burr (M-8/9MH30 with light pressure. This procedure was repeated while dripping saline onto the burr and bone. Data was compared between groups using a student t-test.Application of coolant at the bone-burr interface during decortication resulted in a significant decrease in final temperature. Without coolant, maximum temperatures 2mm from the surface were not sufficient to cause thermal osteonecrosis, although peak surface temperatures would cause local damage. The use of a high speed burr provides a quick and effective method of vertebral end plate preparation. Thermal damage to the bone can be minimised through the use of light pressure and saline coolant. This has implications for any bone preparation performed with a high speed burr.

  11. The Effect of Saline Coolant on Temperature Levels during Decortication with a Midas Rex: An in Vitro Model Using Sheep Cervical Vertebrae.

    Science.gov (United States)

    Livingston, Asher; Wang, Tian; Christou, Chris; Pelletier, Matthew H; Walsh, William R

    2015-01-01

    Decortication of bone with a high-speed burr in the absence of coolant may lead to local thermal necrosis and decreased healing ability, which may negatively impact clinical outcome. Little data are available on the impact of applying a coolant during the burring process. This study aims to establish an in vitro model to quantitatively assess peak temperatures during endplate preparation with a high-speed burr. Six sheep cervical vertebrae were dissected and mounted. Both end plates were used to give a total of 12 sites. Two thermocouples were inserted into each vertebra, 2 mm below the end plate surface and a thermal camera set up to measure surface temperature. A 3 mm high-pneumatic speed burr (Midas Rex, Medtronic, Fort Worth, TX, USA) was used to decorticate the bone in a side to side sweeping pattern, using a matchstick burr (M-8/9MH30) with light pressure. This procedure was repeated while dripping saline onto the burr and bone. Data were compared between groups using a Student's t-test. Application of coolant at the bone-burr interface during decortication resulted in a significant decrease in final temperature. Without coolant, maximum temperatures 2 mm from the surface were not sufficient to cause thermal osteonecrosis, although peak surface temperatures would cause local damage. The use of a high-speed burr provides a quick and an effective method of vertebral end plate preparation. Thermal damage to the bone can be minimized through the use of light pressure and saline coolant. This has implications for any bone preparation performed with a high-speed burr.

  12. Sedación paliativa (parte I: Controversias sobre términos, definiciones y aplicaciones clínicas Sedação paliativa (parte I: Controvérsias sobre termos, definições e aplicações clínicas Palliative sedation (part I: Controversies about terms, definitions and clinical applications

    Directory of Open Access Journals (Sweden)

    Paulina Taboada R.

    Full Text Available El artículo analiza el uso de la sedación paliativa como una herramienta terapéutica potencialmente muy útil en Medicina Paliativa. Se propone que, aunque los conocimientos médicos sobre esta práctica clínica han avanzado bastante en la última década, la evidencia empírica disponible sigue siendo limitada y la controversia persiste. El debate actual incluye aspectos como: las definiciones y la terminología a utilizar (sedación paliativa vs. terminal; los tipos de sedación que se incluyen bajo ese término (intermitente vs. continua; superficial vs. profunda; las indicaciones clínicas (síntomas físicos vs. sufrimiento existencial; el uso concomitante vs. la suspensión de la hidratación y la nutrición médicamente asistida, y los fundamentos éticos y su diferencia con la eutanasia y/o el suicidio médicamente asistido. Se revisan algunos aspectos del debate actual sobre el concepto de “sedación paliativa” y sus diferentes definiciones, así como también ciertas controversias relacionadas con sus aplicaciones clínicas. Aunque se mencionan brevemente algunas cuestiones éticas relacionadas con esta práctica clínica, éstas no se abordan directamente en este artículo, sino que se dejan deliberadamente para un análisis más profundo en una segunda parte.O artigo analisa o uso da sedação paliativa como uma ferramenta terapêutica potencialmente muito útil em Medicina Paliativa. Propõe-se que, ainda que os conhecimentos médicos sobre esta prática clínica tenham avançado bastante na última década, a evidência empírica disponível segue sendo limitada e a controvérsia persiste. O debate atual inclui aspectos como: as definições e a terminologia a ser utilizada (sedação paliativa vs. terminal; os tipos de sedação que são incluidas sob esse termo (intermitente vs. contínua; superficial vs. profunda; as indicações clínicas (sintomas físicos vs. sofrimento existencial; o uso concomitante vs. a suspens

  13. Perceptions of dentists, dentistry undergraduate students, and the lay public about dental sedation Percepção de cirurgiões-dentistas, acadêmicos de odontologia e público leigo sobre sedação em odontologia

    Directory of Open Access Journals (Sweden)

    Luciane Ribeiro de Rezende Sucasas da Costa

    2004-09-01

    Full Text Available Sedation is an option for controlling fear and anxiety related to a visit to the dentist. The goal of this study was to capture, by means of a questionnaire, the perceptions of twenty dentists, twenty dental students and twenty lay people concerning the use of sedatives in a dental environment. The responses were evaluated using the quantitative-interpretative method. Dentists: 75% had knowledge of sedatives in a dental setting, but their actual use was mentioned by only three. As far as the use of sedatives by dentists is concerned, one considered it "risky" and 19 were favorable. Two affirmed that sedation does not present risks. Eighteen said they would be able to react to a medical emergency. Dental students: 60% said they were aware of the topic, in theory. Nineteen expressed interest in the topic. Fifteen claimed there were risks associated with the technique. Twelve (60% have the theoretical knowledge to deal with a medical emergency in the dental office. Lay public: Seven (35% responded that they felt some discomfort during dental treatment, because of fear (n=6 and equipment noise (n=2. Five said they would go to the dentist more often if there was a way to reduce the discomfort. Half of those interviewed indicated that they knew what sedation was. Sixteen favored using it for dental treatment. Seven thought that there were no risks when sedation is carried out. It was concluded that few participants in any of the three categories felt confident about the topic, though they demonstrated interest. The population in general felt optimistic, while practicing dentists and dental students complained of a lack of exposure to the subject at dental school.A sedação constitui-se em opção no controle do medo e da ansiedade relacionados à visita ao dentista. Propôs-se captar a percepção de 20 cirurgiões-dentistas, 20 acadêmicos de odontologia e 20 leigos sobre a utilização de recursos sedativos em ambiente odontológico, através da

  14. Incipient sympatric speciation in Midas cichlid fish from the youngest and one of the smallest crater lakes in Nicaragua due to differential use of the benthic and limnetic habitats?

    Science.gov (United States)

    Kautt, Andreas F; Machado-Schiaffino, Gonzalo; Torres-Dowdall, Julian; Meyer, Axel

    2016-08-01

    Understanding how speciation can occur without geographic isolation remains a central objective in evolutionary biology. Generally, some form of disruptive selection and assortative mating are necessary for sympatric speciation to occur. Disruptive selection can arise from intraspecific competition for resources. If this competition leads to the differential use of habitats and variation in relevant traits is genetically determined, then assortative mating can be an automatic consequence (i.e., habitat isolation). In this study, we caught Midas cichlid fish from the limnetic (middle of the lake) and benthic (shore) habitats of Crater Lake Asososca Managua to test whether some of the necessary conditions for sympatric speciation due to intraspecific competition and habitat isolation are given. Lake As. Managua is very small (Midas cichlids, Amphilophus tolteca. We found that fish from the limnetic habitat were more elongated than fish collected from the benthic habitat, as would be predicted from ecomorphological considerations. Stable isotope analyses confirmed that the former also exhibit a more limnetic lifestyle than the latter. Furthermore, split-brood design experiments in the laboratory suggest that phenotypic plasticity is unlikely to explain much of the observed differences in body elongation that we observed in the field. Yet, neutral markers (microsatellites) did not reveal any genetic clustering in the population. Interestingly, demographic inferences based on RAD-seq data suggest that the apparent lack of genetic differentiation at neutral markers could simply be due to a lack of time, as intraspecific competition may only have begun a few hundred generations ago.

  15. Midodrine as adjunctive support for treatment of refractory hypotension in the intensive care unit: a multicenter, randomized, placebo controlled trial (the MIDAS trial).

    Science.gov (United States)

    Anstey, Matthew H; Wibrow, Bradley; Thevathasan, Tharusan; Roberts, Brigit; Chhangani, Khushi; Ng, Pauline Yeung; Levine, Alexander; DiBiasio, Alan; Sarge, Todd; Eikermann, Matthias

    2017-03-21

    Patients admitted to intensive care units (ICU) are often treated with intravenous (IV) vasopressors. Persistent hypotension and dependence on IV vasopressors in otherwise resuscitated patients lead to delay in discharge from ICU. Midodrine is an oral alpha-1 adrenergic agonist approved for treatment of symptomatic orthostatic hypotension. This trial aims to evaluate whether oral administration of midodrine is an effective adjunct to standard therapy to reduce the duration of IV vasopressor treatment, and allow earlier discharge from ICU and hospital. The MIDAS trial is an international, multicenter, randomized, double-blind, placebo-controlled clinical trial being conducted in the USA and Australia. We are targeting 120 patients. Adult patients admitted to the ICU who are resuscitated and otherwise stable on low dose IV vasopressors for at least 24 h will be considered for recruitment. Participants will be randomized to receive midodrine (20 mg) or placebo three times a day, in addition to standard care. The primary outcome is time (hours) from initiation of midodrine or placebo to discontinuation of IV vasopressors. Secondary outcomes include time (hours) from ICU admission to discharge readiness, ICU length of stay (LOS) (days), hospital LOS (days), rates of ICU readmission, and rates of adverse events related to midodrine administration. Midodrine is approved by the Food and Drug Administration (FDA) for the treatment of symptomatic orthostatic hypotension. In August 2010, FDA proposed to withdraw approval of midodrine because of lack of studies that verify the clinical benefit of the drug. We obtained Investigational New Drug (IND 113,330) approval to study its effects in critically ill patients who require IV vasopressors but are otherwise ready for discharge from the ICU. A pilot observational study in a cohort of surgical ICU patients showed that the rate of decline in vasopressor requirements increased after initiation of midodrine treatment. We

  16. Pharmaceutical expenditure on drugs for rare diseases in Canada: a historical (2007-13) and prospective (2014-18) MIDAS sales data analysis.

    Science.gov (United States)

    Divino, Victoria; DeKoven, Mitch; Kleinrock, Michael; Wade, Rolin L; Kim, Tony; Kaura, Satyin

    2016-05-21

    Health Canada has defined rare diseases as life-threatening, seriously debilitating, or serious chronic conditions affecting a very small number of patients (~1 in 2,000 persons). An estimated 9 % of Canadians suffer from a rare disease. Drugs treating rare diseases (DRDs) are also known as orphan drugs. While Canada is currently developing an orphan drug framework, in the United States (US), the Orphan Drug Act (ODA) of 1983 established incentives for the development of orphan drugs. This study measured total annual expenditure of orphan drugs in Canada (2007-13) and estimated future (2014-18) orphan drug expenditure. Orphan drugs approved by the US Food and Drug Administration (FDA) in the US were used as a proxy for the orphan drug landscape in Canada. Branded, orphan drugs approved by the FDA between 1983 through 2013 were identified (N = 356 unique products). Only US orphan drugs with the same orphan indication(s) approved in Canada were included in the analysis. Adjustment via an indication factoring was applied to products with both orphan and non-orphan indications using available data sources to isolate orphan-indication sales. The IMS Health MIDAS database of audited biopharmaceutical sales was utilized to measure total orphan drug expenditure, calculated annually from 2007-2013 and evaluated as a proportion of total annual pharmaceutical drug expenditure (adjusted to 2014 CAD). Between 2007 and 2013, expenditure was measured for a final N = 147 orphan drugs. Orphan drug expenditure totaled $610.2 million (M) in 2007 and $1,100.0 M in 2013, representing 3.3- 5.6 % of total Canadian pharmaceutical drug expenditure in 2007-2013, respectively. Future trend analysis suggests orphan drug expenditure will remain under 6 % of total expenditure in 2014-18. While the number of available orphan drugs and associated expenditure increased over time, access remains an issue, and from the perspectives of society and equity, overall spending on orphan drugs

  17. Meeleparanduslik teater / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2006-01-01

    Autor tunneb muret ühe uue tendentsi pärast, mida kohtab nii teatri NO99 ja Von Krahli viimastes lavastustes ("Nafta" ja "Võluflööt") kui teisteski teatrites (Linnateatri "Genoom"). Seda tendentsi nimetab ta "meeleparanduslikuks teatriks" ja näeb selles mitmeid probleeme

  18. Ikestatud rahvaste nädal New Yorgis. New York City, 16. - 23 juuli 2006 / Juta Kurman

    Index Scriptorium Estoniae

    Kurman, Juta, 1912-2015

    2006-01-01

    1959. aastal president Eisenhoweri poolt välja kuulutatud 3. nädal juulis on Ikestatud Rahvaste Nädal, mida on tähistatud 48 korda. Sellel aastal tähistati seda jumalateenistuste, meeleavalduste, resolutsiooni vastuvõtmise ja kultuuriprogrammiga

  19. Vanaduse stereotüübid : essee : suhtumises pensionäridesse väljendub ühiskonna moraalsus või moraalitus / Voldemar Kolga

    Index Scriptorium Estoniae

    Kolga, Voldemar, 1947-

    2004-01-01

    Artikkel tugineb ettekandele, mille autor pidas Tallinna Kunstihoones väljas olnud vananemist käsitleva näitusega "Homo grandis natu" kaasnevas loengusarjas. Eakatesse inimestesse suhtutakse soodsalt primitiivsetes ühiskondades, mida tsiviliseeritum on ühiskond, seda negatiivsemalt suhtutakse vanuritesse ja selle üheks põhjuseks on surmahirm

  20. Miljardär Armin Karu hakkab telestaariks / Heidit Kaio

    Index Scriptorium Estoniae

    Kaio, Heidit, 1971-

    2007-01-01

    TV3 on Eesti Ekspressi andmetel jõudmas kokkuleppele, et tuua järgmisest hooajast ekraanile saatesari, mida võiks nimetada "Suurim tööintervjuu". Ameerika Ühendriikides tuli saade ekraanile 2004. aastal, kus seda juhtis miljardär Donald Trump

  1. Ettevaatust, internetikasiino! / Kerli Nõu

    Index Scriptorium Estoniae

    Nõu, Kerli

    2004-01-01

    Interneti-kasiinoäriga tegelev World Games Inc. on jõudnud ka Eestisse. Firma paneb mängijate leidmiseks inimesed endale oma mängijate võrku looma, mida rohkem inimesi võrku kaasatakse, seda tulusamaks muutub äri kaasaja jaoks. Lisad: Tulukroonid; WGI äri ulatub otsapidi teemandi- ja kullakaevandamisse

  2. Differentiating for loyalty / Ivar Soone

    Index Scriptorium Estoniae

    Soone, Ivar, 1975-

    2004-01-01

    Autor väidab, et kui on suudetud tekitada tarbija seotus ja sellel põhinev lojaalsus, saab turundaja võtta kasumit seda enam, mida kõrgema astme lojaalsusega on tegemist. Selline kasumi juhtimine muutub jätkusuutlikkuse ning konkurentsieelise hoidmisel üha olulisemaks. Graafikud. Tabelid

  3. Informatsiooni asümmeetria riskikapitali rahanduses ettevõtja ja riskikapitalisti vahel / Margus Kõomägi

    Index Scriptorium Estoniae

    Kõomägi, Margus

    2004-01-01

    Informatsiooni asümmeetria ettevõtja ja riskikapitalisti vahel on seda suurem, mida suurem on nende vaheline kaugus. Selle väitega rõhutab autor, et ettevõte globaliseeruvas maailmas jääb enamasti seetõttu riskikapitali suhtes kaotajaks. Tabelid. Graafikud

  4. Millest on tehtud arhitektuur? = What is architecture made of? / Indrek Rünkla

    Index Scriptorium Estoniae

    Rünkla, Indrek, 1971-

    2009-01-01

    Arhitekt Indrek Rünkla ettekujutus sellest, mida arhitekt teeb ja tegema peaks, ning ühiskonna vastav kujutus ei kattu. Ta püüab kirjeldada seda osa arhitektuurist, mis ühiskonna arhitektuuripildist välja tahab jääda

  5. Puhtus ja kord majas ning mõtetes / Ene Vool

    Index Scriptorium Estoniae

    Vool, Ene, 1948-

    2007-01-01

    Kalle Rõõmuse projekteeritud inimese bioenergiast lähtuvast eramust, kus raudse järjekindlusega kasutati energeetilisest seisukohast ülimalt inimsõbralikke loodusmaterjale - mida vähem materjale, seda vähem väljamõjusid. Sisearhitekt oli Terje Kivist. Kalle Rõõmuse kommentaar

  6. Naised ja mehed poliitiliste otsuste tasandil = Men and women at the level of political decisions / Ülle-Marike Papp

    Index Scriptorium Estoniae

    Papp, Ülle-Marike

    2006-01-01

    Naiste ja meeste osatähtsus poliitiliste otsuste tasandil on demokraatia arengutaseme põhinäitajaid, mida hierarhilisem ja autoritaarsem on kultuur, seda raskem on naistel poliitikas kõrgele jõuda. Naiste osatähtsus seadusandliku ja täitevvõimu tasandil. Tabelid

  7. Gazprom - lõks Venemaale endale / Kaarel Tarand

    Index Scriptorium Estoniae

    Tarand, Kaarel, 1966-

    2006-01-01

    Hans Rebase Euroopa Instituudi korraldatud konverentsil tõdeti muu hulgas, et mida ulatuslikumalt Venemaa ainult ühele kaardile - maagaasile - mängib, seda hukatuslikum see talle on. Julgustades ja finantseerides laenudega Gazpromi arendamist, ehitatakse Venemaast multifunktsionaalset riiki, mille kogu elu sõltub ühe tööstuse tegevusest, ütleb autor

  8. Harmooniline töötaja on väärtuslik / Kristine Täht

    Index Scriptorium Estoniae

    Täht, Kristine

    2005-01-01

    Rahvastikuministri nõuniku hinnangul on ühiskond seda jätkusuutlikum, mida rohkem on tema arengusse kaasatud õnnelikke inimesi. Selleks peaksid aga riik ja ettevõtjad senisest enam pöörama tähelepanu töötajate eraelule

  9. Häda protokolli pärast = The trouble with the protocol / Indrek Rünkla

    Index Scriptorium Estoniae

    Rünkla, Indrek, 1971-

    2015-01-01

    Artiklis on käsitletud arhitektidele 21. sajandil esitatud nõudeid. Ta peab valdama ja praktiseerima teatud hulka tegevusi, mida ühiskond temalt tellib. Arhitekti tegevus on reguleeritud normatiivide ja protokollidega. Kuigi normid ja seadused on ühiskonnale vajalikud, siis nendega liialdamine hakkab süsteemi koormama, selle asemel et seda toetada ja arendada

  10. Maakasutuse legaalsed ja moraalsed aspektid : Hiina juhtum = Laws and moralaty of land use : the case of China / Anne Haila

    Index Scriptorium Estoniae

    Haila, Anne

    2008-01-01

    Vaadeldakse, millised muutused on toimunud Hiina maahaldussüsteemis ja maakasutuses. Tagasivaade maareformide ajaloole, ülevaade Hiina kaasaegsetest reformidest ning seda toetavatest rahvusvahelistest nõustajatest. Mõningatest probleemidest, mida institutsionaalne muutus ja uus turujaotus on kaasa toonud, ebaselgetest omandiõigustest. Bibliograafia lk. 83

  11. Gurtshenko spojot pro pjat minut 50 let spustja / Olga Saburova

    Index Scriptorium Estoniae

    Saburova, Olga

    2006-01-01

    Režissöör Eldar Rjazanov teeb oma vene kultusfilmi "Karnevaliöö" uut, 50 aastat hilisemasse aega, s.o. tänapäeva, toodud varianti "Karnevaliöö 2 ". Seda näidatakse Venemaa Esimesel Kanalil uusaastakavas. Lähemalt sellest, keda ja mida selles filmis näeb-kuuleb

  12. Bush skazal ne sovsem to, tshto skazal

    Index Scriptorium Estoniae

    2006-01-01

    USA abivälisminister Euroopa ja Euraasia küsimustes Daniel Fried teatas, et NATO riigid toetavad Gruusia, Moldova ja Aserbaidžaani territoriaalset terviklikkust, kuid ei luba neil seda taastada relva abil. Abiminister selgitab, mida pidas USA president George W. Bush silmas, kui ta avaldas Riia tippkohtumisel toetust Gruusiale tema püüdlustes liituda NATO-ga

  13. Piraatlus Guinea lahes ja Nigeerias / Eero Tepp

    Index Scriptorium Estoniae

    Tepp, Eero

    2013-01-01

    Guinea lahes lokkava piraatluse põhjused ja tegurid, mis seda soodustavad: seaduselüngad, looduslikud tingimused, ebapädev korrakaitse, poliitiline olustik, kultuuriline vastuvõetavus, majanduslik tasuvus. Sõjalised ja mittesõjalised meetmetest, mida rakendatakse piraatlusevastases võitluses

  14. Internet nagu postiteenus / Anneli Ammas

    Index Scriptorium Estoniae

    Ammas, Anneli, 1962-

    2004-01-01

    Majandus- ja kommunikatsiooniminister Meelis Atoneni sõnul peaks Interneti-teenus muutuma sarnaseks postiteenusega, millel on ühtne hind üle Eesti. Bill Gates on huvitatud Eesti ettepanekust pakkuda Eesti kodutarbijale tarkvara tervikpaketist vaid seda osa, mida tarbija tegelikult kasutab

  15. Nord Stream on väljakutse kodanikuühiskonnale / Tarmo Soomere ; üles kirjutanud Juune Holvandus

    Index Scriptorium Estoniae

    Soomere, Tarmo, 1957-

    2009-01-01

    Gaasijuhe Nord Stream läbi Läänemere Venemaalt Saksamaale ei tähenda ainult kasulikku äritehingut. Küsimus on ennekõike ohutust keskkonnast ja sellest, et riigid peavad kaaluma ka seda, mida järeltulevad põlved asjast arvavad. Akadeemik Tarmo Soomere selgitab rahvusvahelistesse vetesse rajatava gaasijuhtme temaatikat.

  16. President kutsub noori mõttetalgutele / Aire Vaher

    Index Scriptorium Estoniae

    Vaher, Aire

    2009-01-01

    President Toomas Hendrik Ilves kuulutas 27. veebruaril 2009 Tartus Eesti Kirjandusmuuseumis välja kooliõpilaste ja tudengite kirjatalgud teemal "Mida mina saan teha Eesti heaks?". Ilmunud ka (ilma autorita): Lääne Elu 3. märts 2009, lk. 5, pealk.: Presidendi kirjatalgud ootavad osalejaid; Pärnu Postimees 4. märts 2009, lk. 6, pealk.: President kutsub kirjatalgutel osalema; Õpetajate Leht 6. märts 2009, lk. 17, pealk.: Vabariigi presidendi kirjatalgud 2009; Mente et Manu 6. märts 2009, lk. 2, pealk.: Vabariigi Presidendi kirjatalgud 2009; Vaba Eesti Sõna 5. märts 2009, lk. 2, pealk.: Noorte kirjatalgud "Mida mina saan teha Eesti heaks?"

  17. Ultrastructure of the silk glands in three adult females of sphecid wasps of the genus Microstigmus (Hymenoptera: Pemphredoninae Ultraestructura de las glándulas de seda en hembras adultas de tres especies de avispas del género Microstigmus (Hymenoptera: Sphecidae: Pemphredoninae

    Directory of Open Access Journals (Sweden)

    JOSÉ EDUARDO SERRÃO

    2005-03-01

    Full Text Available The ultrastructure of silk glands in adult females of sphecid wasps is described. Individual glands are scattered in the more posterior portion of the metasoma being each gland formed by an enlarged secretory unity with one conducting canal. Each secretory unit is a gland cell containing a large lumen and numerous secretory granules, which are delimited by membrane and filled with middle electron dense content of homogeneous aspect, which are exocytosed into the extra cellular lumen. Cell cytoplasm is filled with rough endoplasmic reticulum, polyribosomes and Golgi apparatuses profiles. The basal plasma membrane has many short infoldings and is lined by a thin basement membrane. The apical membrane is invaginated to form the boundary of the lumen, containing scattered short microvilli. The cells are mononucleated and the nucleus is pleomorphic containing disperse chromatin. The extracellular lumen is separated of the receiving canal by a convoluted sponge-like wall forming many villi, which in their tip are lined by a thin single layered cuticle. In the basal region of the villi a cuticular covering is lacking. In the conducting canal secretion acquire two different electron densities. A thin cuticle lines the lumen of conducting canal and the cell cytoplasm is scarce and the organelles are represented for few rough endoplasmic reticulum and polyribosomes. These results are discussed in relation to function and origin of silk gland in adult SphecidaeSe describe la ultraestructura de las glándulas de la seda en tres hembras adultas de avispas Sphecidae del género Microstigmus. Las glándulas individualmente se dispersan en la porción más posterior del metasoma, y cada una de ellas está formada por una unidad secretora grande y un canal que conduce la secreción. Cada célula de la unidad secretora contiene un gran lumen y numerosos gránulos secretores, los que están delimitados por una membrana y repletos de un contenido denso a los

  18. Clonidina e dexmedetomidina por via peridural para analgesia e sedação pós-operatória de colecistectomia Clonidina y dexmedetomidina por vía peridural para analgesia y sedación pós-operatoria de colecistectomía Epidural clonidine or dexmedetomidine for post-cholecystectomy analgesia and sedation

    Directory of Open Access Journals (Sweden)

    Antônio Mauro Vieira

    2004-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A clonidina e a dexmedetomidina são agonistas alfa2-adrenérgicos que, quando administrados por via peridural, possuem propriedades analgésicas e potencializam os efeitos dos anestésicos locais. A presente pesquisa objetivou avaliar a analgesia e a sedação produzidas pela clonidina ou dexmedetomidina associadas à ropivacaína, por via peridural, no pós-operatório de colecistectomia por via subcostal. MÉTODO: Participaram do estudo aleatório e duplamente encoberto 40 pacientes, de ambos os sexos, com idade variando de 18 a 50 anos, peso entre 50 e 100 kg, estado físico ASA I e II, submetidos à colecistectomia por via subcostal, os quais foram distribuídos em dois grupos: clonidina (GC, em que foi administrada clonidina (1 ml = 150 µg associada à ropivacaína a 0,75% (20 ml por via peridural; dexmedetomidina (GD, em que foi injetada dexmedetomidina (2 µg.kg-1 associada à ropivacaína a 0,75% (20 ml por via peridural. A analgesia e a sedação foram observadas 2, 6 e 24 horas após o término da anestesia. RESULTADOS: Ocorreu sedação depois de 2 e 6 horas em ambos os grupos, sendo que houve diferença estatística significante entre os tempos de 2 e 6 horas no grupo dexmedetomidina. Houve analgesia em ambos os grupos, especialmente depois de 2 e 6 horas. Foi detectada diferença estatística significante entre os tempos de 2, 6 e 24 horas no grupo dexmedetomidina; no grupo clonidina essa diferença estatística significante foi observada entre os tempos de 2 e 6 horas e entre 2 e 24 horas. CONCLUSÕES: Os resultados permitiram concluir que a clonidina ou a dexmedetomidina associadas à ropivacaína a 0,75% asseguraram analgesia e sedação nos tempos de observação de 2 e 6 horas após o término da anestesia, nos pacientes submetidos à colecistectomia por via subcostal e que a clonidina promove analgesia mais prolongada.JUSTIFICATIVA Y OBJETIVOS: La clonidina y la dexmedetomidina son agonistas alfa2

  19. Sedação com sufentanil e clonidina em pacientes submetidos a cateterismo cardíaco Sedación con sufentanil y clonidina en pacientes sometidos a cateterismo cardíaco Sedation with sufentanil and clonidine in patients undergoing heart catheterization

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    Anita Perpetua Carvalho Rocha

    2011-03-01

    Full Text Available FUNDAMENTO: A sedação para a realização de cateterismo cardíaco tem sido alvo de preocupação. Benzodiazepínicos, agonistas alfa-2 adrenérgicos e opioides são utilizados para esse fim, entretanto, cada um destes medicamentos possui vantagens e desvantagens. OBJETIVO: Avaliar a eficácia do sufentanil e da clonidina como sedativos em pacientes submetidos a cateterismo cardíaco, observando o impacto dos mesmos sobre os parâmetros hemodinâmicos e respiratórios, a presença de efeitos colaterais, além da satisfação do paciente e do hemodinamicista com o exame. MÉTODOS: Trata-se de um ensaio clínico prospectivo, duplo-cego, randomizado e controlado, que envolveu 60 pacientes que receberam 0,1 µg/kg de sufentanil ou 0,5 µg/kg de clonidina antes da realização do cateterismo cardíaco. O escore de sedação segundo a escala de Ramsay, a necessidade de utilização de midazolam, os efeitos colaterais, os parâmetros hemodinâmicos e respiratórios foram registrados, sendo os dados analisados em 06 diferentes momentos. RESULTADOS: O comportamento da pressão arterial, da frequência cardíaca e da frequência respiratória foi semelhante nos dois grupos, entretanto, no momento 2, os pacientes do grupo sufentanil (Grupo S apresentaram menor escore de sedação segundo a escala de Ramsay, e a saturação periférica da oxihemoglobina foi menor que o grupo clonidina (Grupo C no momento 6. Os pacientes do Grupo S apresentaram maior incidência de náusea e vômito pós-operatório que os pacientes do Grupo C. A satisfação dos pacientes foi maior no grupo clonidina. Os hemodinamicistas mostraram-se satisfeitos nos dois grupos. CONCLUSÃO: O sufentanil e a clonidina foram efetivos como sedativos em pacientes submetidos a cateterismo cardíaco.FUNDAMENTO: La sedación para la realización de cateterismo cardíaco ha sido blanco de preocupación. Benzodiazepínicos, agonistas alfa-2 adrenérgicos y opioides son utilizados para ese fin

  20. Sedação e analgesia em crianças: uma abordagem prática para as situações mais freqüentes Analgesia and sedation in children: practical approach for the most frequent situations

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    Santiago Mencía Bartolomé

    2007-05-01

    Full Text Available OBJETIVOS: Revisar as indicações, doses e formas de administração dos sedativos, analgésicos e relaxantes musculares mais utilizados na criança, bem como os métodos de monitorização da sedação. FONTES DOS DADOS: Levantamento bibliográfico utilizando a base de dados MEDLINE e revisão da experiência em nossas unidades de cuidados intensivos pediátricos. SÍNTESE DOS DADOS: A administração contínua de drogas analgésicas e sedativas impede o aparecimento das fases de subsedação e requer menor assistência do que na administração intermitente. O midazolan é a droga mais utilizada para sedação contínua da criança gravemente enferma. Os derivados opiáceos e os antiinflamatórios não-hormonais são os analgésicos mais utilizados na criança gravemente enferma. Os opióides associados aos benzodiazepínicos em infusão contínua são os fármacos de eleição em crianças em ventilação mecânica, especialmente a morfina e o fentanil. O uso de protocolos e a monitorização com a utilização de escores clínicos e métodos objetivos como o BIS permitem ajustar mais corretamente a medicação, evitando a supersedação, a subsedação e a síndrome de abstinência. As intervenções não-farmacológicas, como a musicoterapia, o controle de ruídos, a adequada utilização da luz, a massagem e a comunicação com o paciente, são medidas complementares que auxiliam na adaptação da criança ao ambiente hospitalar adverso. CONCLUSÕES: A sedação deve ser adaptada a cada criança em cada momento. O emprego de protocolos que facilitem uma correta seleção de fármacos, uma administração adequada e uma monitorização cuidadosa melhoram a qualidade da sedoanalgesia e reduzem seus efeitos adversos.OBJECTIVES: To review the most frequent recommendations, doses and routes of administration of sedatives, analgesics, and muscle relaxants in children, as well as the methods for monitoring the level of sedation. SOURCES: Review

  1. Leaf Surface Scanning Electron Microscopy of 16 Mulberry Genotypes (Morus spp. with Respect to their Feeding Value in Silkworm (Bombyx mori L. Rearing Microscopía Electrónica de Barrido de la Superficie Foliar de 16 Genotipos de Morus spp. en Relación a su Valor Alimenticio para Crianza del Gusano de la Seda (Bombyx mori L.

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    B.K Singhal

    2010-06-01

    Full Text Available Mulberry (Morus spp. is the only silkworm (Bombyx mori L. food plant. In Indian sub tropics, S-146 is the only popular and ruling mulberry genotype for silkworm rearing. As a result, mulberry leaf availability is always the limiting factor, and therefore, sub tropics are contributing less than 1% of the country’s total silk production compared with more than 60% under tropical conditions. Besides climatic conditions, this is due to a very limited number of mulberry genotypes available in this region for silkworm rearing. However, in the mean time, 15 mulberry genotypes viz. ‘Tr-10’,‘Chinese White’,‘K-2’,‘Sujanpur Local’,‘BC2-59’,‘S-1635’,‘C-1730’,‘Mandalaya’,‘S-30’‘(Vishala,‘RFS-175’,‘Anantha’,‘C-2016’,‘C-2017’,‘S-41’ and‘V-1’ were also introduced in the sub tropics, but remained unexplored. In sericulture, leaf surface is also an important parameter for, both, the silkworm’s acceptability of not having any feeding impediment and the mulberry improvement programs. The objective of this study was to explore the possibilities of using these 16 mulberry genotypes for their leaf surface characteristics by scanning electron microscopy and using them for sericulture. Based on leaf yield, stomatal size, stomatal number per unit of area and trichomes and idioblasts length, these genotypes were grouped into different categories. The mulberry genotype ‘Mandalaya’, in addition to the ruling genotype ‘S-146’ excelled because of their higher leaf yield and desired leaf surface characteristics. Furthermore, the genotypes ‘K-2’, ‘S-41’ and ‘Sujanpur Local’ are also suggested to develop high yield mulberry genotypes in the Indian sub tropics.La morera (Morus spp. es la única planta de alimento para el gusano de la seda (Bombyx mori L.. En los sub-trópicos de la India, ‘S-146’ es el único genotipo popular y predominante de morera para criarlo. Como resultado, la

  2. Ettevõtted jäävad eesmärkide elluviimisega hätta / Silva Laius, Ilmar Raudsep

    Index Scriptorium Estoniae

    Laius, Silva

    2004-01-01

    Juhtimises on olulisimaks teemaks tõusnud ettevõtte eesmärkide elluviimine. McKinsey ja FranklinCovey uuringust, mille eesmärk oli vastata küsimusele, mida teha, et olla nende hulgas, kes saavutavad eesmärke ja loovad väärtust. Larry Bossidy ja Ram Charani raamatust "Execution". Vt. samas: xQ protsess aitab täideviimise võimet tõsta. Tabel, diagramm

  3. Pärnu võitleb oma hõlmikpuuga / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2000-01-01

    Pärnu linnavalitsuselt ei ole tulnud ehitusluba Uue Kunsti Muuseumi ehituse alustamiseks. Muuseumi näitusepoliitikast. Näitustest "Mees ja naine" ja "Õndsate kunst", tänavusi külalisesinejaid, pikemalt Joel Peter Witkinist ja tööst, mida ta tahab Pärnus teha. Stephan Hörhammeri maalinäitusest "Universumi silmad". Harald Keilandi kunstikogu valiknäitusest. Euroopa õndsate kunstnike näitus "Laevad" avatakse Mudaravilas

  4. Kolm küsimust esimese leedi kandidaatidele

    Index Scriptorium Estoniae

    2001-01-01

    Tiia Tulviste, Kirsti Savi, Sirje Priimägi, Mari-Ann Kelam ja Mari Tarand vastavad küsimustele, kuidas nad suhtuvad sattumisse presidendikampaaniasse, millisena nad näevad enda rolli presidendivalimiste kampaanias ja mida nad tahaksid teha esimese leedina. Eesti presidendi abikaasa rollist ühiskonnast räägivad Jaak Allik, Enn Eesmaa, Toomas Tiivel, Vilja Savisaar ja Gunnar Paal. Parlamendisaadik (M.-A. Kelam)

  5. Otvetshajet : Nele Labi : rukovoditel otdela Estonskogo departamenta rõnka truda / Nele Labi

    Index Scriptorium Estoniae

    Labi, Nele

    2007-01-01

    Tööturuameti osakonnajuhataja vastab küsimustele, kas on normaalne niisugune olukord, et iga neljas tööeas inimene ei tööta ega püüagi tööd leida, milliseid teenuseid tööturuamet pakub neile, kes tahavad tööd leida ning mida teha neil, kes on kaotanud lootuse leida tööd oma vanuse või tervise tõttu

  6. Enesessetõmbumine ehk Ungari välispoliitika argipäevad / Anita Orban ; tõlk. Ivar Sinimets

    Index Scriptorium Estoniae

    Orban, Anita

    2006-01-01

    Autor leiab, et Ungari välispoliitika on toodud sisepoliitikale ohvriks ja seetõttu suudetakse saavutada ainult murdosake sellest, mida tegelikult tuleks ja saaks teha. Ungari diplomaatia pole võimeline pärast liitumisläbirääkimisi ELiga välja töötama või ellu viima Ungari huve hõlmavat kontseptsiooni. Ülevaade riigi poliitilisest olukorrast

  7. Mida pakub Delta? / Teele Kurm

    Index Scriptorium Estoniae

    Kurm, Teele

    2011-01-01

    Politsei- ja Piirivalveamet võtab kasutusele ühise Siseministeeriumi infotehnoloogia- ja arenduskeskuse ning Webmedia AS koostööna loodud dokumendihaldussüsteemi Delta. Kust sai Delta oma nime? Projekti "Dokumendihaldussüsteemi juurutamine Siseministeeriumi haldusalas" eesmärgid

  8. Mida loodavad poliitikud? / Urmas Lauri

    Index Scriptorium Estoniae

    Lauri, Urmas, 1956-

    1998-01-01

    Vastavad T. Jürgenson, S. Ivanov, A. Rüütel, A. Haug, O. Anton, Pärnoja, M. Kubo, S. Kallas, K. Kilvet, M. Treial, E. Truu. Järgneb 20. jaan. 1998, lk. 2; 22. jaan. 1998, lk. 2; 27. jaan. 1998, lk. 2. Ilmunud ka: Hiiu Leht, 20. jaan. 1998, lk. 3

  9. Botulinum toxin: The Midas touch.

    Science.gov (United States)

    Shilpa, P S; Kaul, Rachna; Sultana, Nishat; Bhat, Suraksha

    2014-01-01

    Botulinum Toxin (BT) is a natural molecule produced during growth and autolysis of bacterium called Clostridium botulinum. Use of BT for cosmetic purposes has gained popularity over past two decades, and recently, other therapeutic uses of BT has been extensively studied. BT is considered as a minimally invasive agent that can be used in the treatment of various orofacial disorders and improving the quality of life in such patients. The objective of this article is to review the nature, mechanism of action of BT, and its application in various head and neck diseases.

  10. Mida loed sina? / Indrek Hargla

    Index Scriptorium Estoniae

    Hargla, Indrek, pseud., 1970-

    2007-01-01

    Tutvustus: Pérez-Reverte, Arturo. Dumas̀ klubi ehk Richelieu vari. Tallinn : Varrak, 2006 ; Belials, Veiko. Jumalate vandenõu. Tallinn : Varrak, 2006 ; Põder, Rein. Eike. Tallinn : Eesti Raamat, 2006 ; Reeve, Philip. Kuldseeklid. Tallinn : Tiritamm, 2006 ; Martin, George R. R. Troonide mäng. Esimene raamat / tlk. Mario Kivistik. Tallinn : Varrak, 2006. (Jää ja tule laul) (F-sari)

  11. Efeito do extrato aquoso do algodão de seda (Calotropis procera Aiton sobre a eficiência reprodutiva do carrapato bovino Effect of aqueous extract of silk cotton (Calotropis procera Ait. R.Br. on the reproductive performance of Rhipicephalus microplus

    Directory of Open Access Journals (Sweden)

    S.F Lázaro

    2012-01-01

    Full Text Available O carrapato Rhipicephalus microplus é um dos principais parasitos dos rebanhos bovinos. Diferentes grupos de carrapaticidas sintéticos têm sido empregados para o controle desse ácaro, contudo, o uso constante desses produtos tem selecionado populações resistentes. Na tentativa de minimizar esses impactos tem-se buscado avaliar fitoterápicos para o controle desse parasito. Assim, objetivou-se analisar a eficácia in vitro do extrato aquoso do algodão de seda em diferentes concentrações no controle da postura e eclodibilidade dos ovos do R. microplus. Foram avaliados os efeitos das concentrações 1, 5, 10, 25, 50, 75 e 100% do extrato aquoso obtido juntamente com controles com água destilada ou com cipermetrina, 12,5 mg L-1, associada a organofosforado, 150 mg L-1, sobre a eficiência reprodutiva do carrapato. Foi realizado o biocarrapaticidograma sendo que a eficácia acaricida das concentrações 5, 25 e 100% foram superiores àquela observada para o produto comercial utilizado, que correspondeu a 93,98%, indicando a importância de futuras pesquisas para avaliar o potencial toxigênico e a eficácia in vivo dessa planta para o controle do R. microplus .The tick Rhipicephalus microplus is one of the main parasites of bovine herds. Different groups of synthetic acaricides have been used to control this mite; however, the constant use of these products has selected resistant populations. In an attempt to minimize these impacts, researchers have tried to evaluate herbal remedies to control this parasite. Therefore, the aim of this study was to analyze the in vitro efficacy of aqueous extract of silk cotton at different concentrations to control the hatchability of R. microplus eggs. The effects of the concentrations 1, 5, 10, 25, 50, 75 and 100% aqueous extract together with controls with distilled water or with cypermethrin, 12.5 mg L-1, associated with organophosphate, 150 mg L-1, were assessed on the reproductive efficiency of the

  12. Predictive factors of oxygen desaturation of patients submitted to endoscopic retrograde cholangiopancreatography under conscious sedation Fatores preditivos de dessaturação de oxigênio de pacientes submetidos a colangiopancreatografia endoscópica retrógrada sob sedação consciente

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    Suzana Müller

    2004-09-01

    Full Text Available BACKGROUND AND AIMS: Hypoxemia can occur during endoscopic retrograde cholangiopancreatography probably induced by the analgesia and sedation done. Moreover the patient’s prone position difficults the adequate ventilation. The hypoxemia and hypoventilation may not be noticed by nursing staff. A transversal study was used to investigate possible predictive factors of oxygen desaturation in sedated patients with midazolam associated to meperidine undergoing endoscopic retrograde cholangiopancreatography. PATIENTS AND METHODS: A total of 186 patients were monitored with continuous pulse oximetry. Poisson regression was used to measure the independent effect of each factor adjusted for effects of each of the other factors. The variables studied were: age, gender, hematocrit and hemoglobin levels, scopolamine use, diagnostic or therapeutic exam, American Society of Anesthesiologists Scores (ASA, duration time of exam, sedative used midazolam in the average of 0.07 mg/kg and analgesic drug meperidine in the average of 0.7 mg/kg that was titrated according patient’s reaction. RESULTS: No desaturation was found in 113 (60.8% patients, mild desaturation (SpO2 60 years old and ASA score III. The duration of exam was barely significant for desaturation. CONCLUSIONS:The variables of age of 60 years old or more, and ASA III score are identified as increased risk for desaturation for patients who undergo endoscopic retrograde cholangiopancreatography under conscious sedation. Long time of exam suggests the patient oxygen desaturate. Such patients require very close monitoring to desaturation and hypoventilation by the assistants and nursing staff alerting to respiratory depression. The use of pulse oximeter and asking for deep breaths during the exam helps to diminish such risks.RACIONAL: A hipoxemia pode ocorrer durante a colangiopancreatografia endoscópica retrógrada, provavelmente induzida pela analgesia e sedação realizadas, além da posição do

  13. Kinnisvara pealt saab teenida seda ostmata / Romet Kreek

    Index Scriptorium Estoniae

    Kreek, Romet, 1972-

    2003-01-01

    Autor tutvustab võimalust investeerida kinnisvarasse läbi kinnisvara haldavate ettevõtete ehk REIT-ide, mille aktsiad on börsil kaubeldavad. Diagramm: REITide tootlus on ületanud aktsiaindeksite oma

  14. Kas usud seda? / Loore Ehrlich ; kommenteerinud Remo Savisaar

    Index Scriptorium Estoniae

    Ehrlich, Loore

    2013-01-01

    Müüdid: Talvituvad herilased kaitsevad pesa raevukalt; Karu tõuseb enne ründamist tagajalgadele; Kõik ämblikud on ohtlikult mürgised; Puuk kukutab end puude-põõsaste okstelt inimesele; Kõrvahark ronib kõrva ja sealt edasi ajju; Rästik jälitab inimest eesmärgiga rünnata; Nahkhiir on verdihkav vampiir; Ilves ründab inimest puuvõrast turja karates; Näljased hundid murravad inimesi; Sosnovski karuputk kõrvetab; Seen mis ussitab on söögi seen

  15. Kuidas pääseda siseringi / Jaana Liigand

    Index Scriptorium Estoniae

    Liigand, Jaana

    2004-01-01

    Autor kirjeldab Art Kleineri raamatule "Who really matters - the core group theory of power, privilege and success" tuginedes erinevat liiki tuumikgruppe, viise neisse pääsemiseks või neisse kuulumata hakkama saamiseks. Vt. samas: Paranoia abil siseringi. Lisa: Kes kuuluvad siseringi?; Kas ma olen paadis?

  16. Dexmedetomidina associada a propofol em sedação durante anestesia local para cirurgia plástica Dexmedetomidina asociada a propofol en sedación durante anestesia local para cirugía plástica Dexmedetomidine/propofol association for plastic surgery sedation during local anesthesia

    Directory of Open Access Journals (Sweden)

    José Roberto Nociti

    2003-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A dexmedetomidina é um novo agonista alfa2-adrenérgico com propriedades potencialmente úteis em anestesia. Este estudo comparativo tem por finalidade observar os efeitos da dexmedetomidina sobre o consumo de propofol e a evolução dos parâmetros cardiovasculares e respiratórios, quando incluída em técnica de sedação durante anestesia local em cirurgia plástica. MÉTODO: Participaram do estudo 40 pacientes do sexo feminino com idades entre 16 e 60 anos, estado físico ASA I ou II, submetidas a cirurgias plásticas eletivas sob anestesia local. Foram distribuídas aleatoriamente em dois grupos de vinte: C (controle e D (dexmedetomidina. Em ambos, a sedação foi obtida com propofol na dose em bolus inicial de 1 mg.kg-1 seguida de infusão contínua em velocidade ajustada para se obter grau de sedação consciente. No grupo D, as pacientes receberam infusão venosa contínua de dexmedetomidina à velocidade de 0,01 µg.kg-1.min-1, concomitante com a de propofol. Foram avaliados: efeito da dexmedetomidina sobre o consumo de propofol; variação dos parâmetros cardiovasculares (PAS, PAD, PAM, FC e respiratórios (SpO2, P ET CO2; qualidade do controle do sangramento per-operatório e características da recuperação pós-anestésica. RESULTADOS: A velocidade média de infusão de propofol foi menor no grupo D (35,2 ± 5,3 µg.kg-1.min-1 do que no grupo C (72,6 ± 8,5 µg.kg-1.min-1. Os valores médios de PAS, PAD e PAM decresceram em relação ao inicial, a partir dos 30 minutos, no grupo D, mantendo-se a seguir estáveis até o final; no grupo C, aumentaram. A FC manteve-se estável no grupo D e aumentou a partir dos 30 minutos no grupo C. O tempo médio para obedecer ao comando de "abrir os olhos" foi menor no grupo D (6,3 ± 2,5 min em relação ao C (8,9 ± 2,7 min. O controle do sangramento per-operatório foi superior no grupo D em relação ao C. CONCLUSÕES: O emprego da dexmedetomidina associada ao

  17. Bifidobacterium reuteri sp. nov., Bifidobacterium callitrichos sp. nov., Bifidobacterium saguini sp. nov., Bifidobacterium stellenboschense sp. nov. and Bifidobacterium biavatii sp. nov. isolated from faeces of common marmoset (Callithrix jacchus) and red-handed tamarin (Saguinus midas).

    Science.gov (United States)

    Endo, Akihito; Futagawa-Endo, Yuka; Schumann, Peter; Pukall, Rüdiger; Dicks, Leon M T

    2012-03-01

    Five strains of bifidobacteria were isolated from faeces of a common marmoset (Callithrix jacchus) and a red-handed tamarin (Saguinus midas). The five isolates clustered inside the phylogenetic group of the genus Bifidobacterium but did not show high sequence similarities between the isolates and to known species in the genus by phylogenetic analysis based on 16S rRNA gene sequences. Sequence analyses of dnaJ1 and hsp60 also indicated their independent phylogenetic positions to each other in the Bifidobacterium cluster. DNA G+C contents of the species ranged from 57.3 to 66.3 mol%, which is within the values recorded for Bifidobacterium species. All isolates showed fructose-6-phosphate phosphoketolase activity. Based on the data provided, the five isolates represent five novel species, for which the names Bifidobacterium reuteri sp. nov. (type strain: AFB22-1(T) = JCM 17295(T) = DSM 23975(T)), Bifidobacterium callitrichos sp. nov. (type strain: AFB22-5(T) = JCM 17296(T) = DSM 23973(T)), Bifidobacterium saguini sp. nov. (type strain: AFB23-1(T) = JCM 17297(T) = DSM 23967(T)), Bifidobacterium stellenboschense sp. nov. (type strain: AFB23-3(T) = JCM 17298(T) = DSM 23968(T)) and Bifidobacterium biavatii sp. nov. (type strain: AFB23-4(T) = JCM 17299(T) = DSM 23969(T)) are proposed. Copyright © 2011 Elsevier GmbH. All rights reserved.

  18. Aeg on Soome ja Rootsi töösturid kinni püüda / Taivo Paju, Kärt Blumberg

    Index Scriptorium Estoniae

    Paju, Taivo, 1968-

    2008-01-01

    Ettevõtete edutegurite üle arutlevad Arengufondi juhatuse liige Heido Vitsur, Balti Uuringute Instituudi juhatuse esimees Marek Tiits, TTÜ mehhaanikateaduskonna professor Rein Küttner. Vt. samas: Ketlin Priilinn. Metsikult kallis küll, kuid seda väärt; Merike Teder. Uute seadmeteta oleksime kadunud (ilmunud ka Molodjozh Estonii : Biznes Sreda 16. apr. lk. 8); Taivo Paju. Pelmeenikuningas Ivan Zakotei (ilmunud ka Molodjozh Estonii : Biznes Sreda 30. apr. lk. 11); Poolteist kuud ja tehas töökorras

  19. Randomized clinical trial comparing spinal anesthesia with local anesthesia with sedation for loop colostomy closure Ensaio clínico randomizado comparando raquianestesia com anestesia local, associadas à sedação para o fechamento de colostomia em alça

    Directory of Open Access Journals (Sweden)

    Rone Antônio Alves de Abreu

    2010-09-01

    pacientes receberam antibioticoprofilaxia com cefoxitina. Dor, analgesia, restabelecimento do peristaltismo, reintrodução da dieta, tempo de internação e de reinternação foram analisados no pós-operatório. RESULTADOS: Duração da cirurgia e complicações locais foram maiores no grupo da raquianestesia. A conversão para anestesia geral ocorreu somente no grupo da raquianestesia. Em relação á dor intraoperatória, não houve diferença entre os grupos, mas a dor pós-operatória, restabelecimento do peristaltismo, reintrodução da dieta e tempo de hospitalização foram menores no grupo com anestesia local. CONCLUSÃO: A anestesia local associada à sedação ofereceu um método mais seguro e efetivo que a raquianestesia para o fechamento de colostomia em alça.

  20. Märgita tooted lahjendavad õlleturgu / Karin Vene

    Index Scriptorium Estoniae

    Vene, Karin, 1983-

    2008-01-01

    Kaubandusketid tellivad tooteid oma märgi all, nn. private label'eid, õlletootjate liidu andmeil on juba kümnendik kodumaisest õlleturust niisuguste toodete käes. Balti riikide toiduainesektori analüütiku Aavo Koppeli väitel sünnib seda vähem private label'eid, mida killustunum on kaubanduskettide turg. Graafikud: Kaubanduse õllebrändid Balti turul

  1. Lojaalsed kliendid ja suhete loomine / Katrin Aedma

    Index Scriptorium Estoniae

    Aedma, Katrin

    2007-01-01

    Teenindust käsitlevate raamatute tutvustus. Seth Godini "Nõusolekuturundus: kuidas muuta võõraid sõpradeks ja sõpru klientideks", Kaj Storbacka ja Jarmo R. Lehtineni "Klientsuse reeglid või tants klientide pilli järgi" ja Frederick F. Reichheldi "Lojaalsuse reeglid. Kuidas edukad juhid loovad kestvaid töö- ja kliendisuhteid". Lisad: Eksimused ja surmapatud teeninduses!; Sellest, mida sa tead, pole kasu, kui sa seda ei kasuta!

  2. Kosovo iseseisvumine ähvardab kättemaksuga / Miljenko Dereta ; interv. Krister Paris

    Index Scriptorium Estoniae

    Dereta, Miljenko

    2007-01-01

    Serbia vabaühenduste üks juhte vastab küsimustele, kuidas võtab Serbia avalikkus vastu seda, et kõnelused Kosovo lõppstaatuse üle lõppevad tõenäoliselt Belgradile ebameeldivalt, mida toob Kosovo iseseisvumine Serbiale, kas ta ootab probleeme ka serblaste poole pealt, kuidas kirjeldada EL-i rolli selle konflikti lahendamisel

  3. Eestis on üle tuhande lõvi : [Lions-liikumisest] / Vello Talviste, Olev Saluveer, Jaan Palumets...[jt.

    Index Scriptorium Estoniae

    2009-01-01

    Lions-liikumisega on ühinenud ka koolidirektorid. Küsimustele - mis ajendas neid seda tegema, mida lõvid ette võtavad ning kui aktuaalne on heategevuse temaatika koolis, vastavad Paide Gümnaasiumi direktor Vello Talviste, Ülenurme Gümnaasiumi direktor Olev Saluveer, Saue Gümnaasiumi direktor Jaan Palumets, Tõrva Gümnaasiumi direktor Ivar Hanvere ja Tabivere Gümnaasiumi direktor Toivo Punga

  4. Mida õppida vanalt healt Inglismaalt? / Margit Sutrop

    Index Scriptorium Estoniae

    Sutrop, Margit, 1963-

    2002-01-01

    Filosoofiaprofessor Margit Sutrop kirjutab teenindajate lojaalsusest. Autorit hämmastab fakt, et presidendi kantselei peakokk räägib leheveergudel sellest, kuidas presidendi perekond mingit sööki omavahel "möksiks" nimetab

  5. Mida tulevikuga peale hakata? / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2014-01-01

    Arvustus: Kaku, Michio. Tulevikufüüsika : kuidas teadus aastal 2100 kujundab inimsaatust ja meie igapäevast elu / tlk. Arko Olesk. Tallinn : Pilgrim, 2013 ; Stevenson, Mark. Optimisti teekond tulevikku : üks uudishimulik sell tahab teada: mis saab edasi? / tlk. Vahur Lokk. Tallinn : Äripäev, 2013

  6. Mida ootame Res Publica poliitikutelt? / Andreas Kaju

    Index Scriptorium Estoniae

    Kaju, Andreas

    2003-01-01

    Res Publica Juventus on piirkondadele saadetud küsitlustega otsinud vastuseid mitmetele probleemidele. Eesmärk Res Publica poliitilise käitumise raamide määramine. Tabel: Juventuse küsimused piirkondadele

  7. Mida ikkagi valitsevad maavalitsused? / Margus Lepik

    Index Scriptorium Estoniae

    Lepik, Margus, 1969-

    2007-01-01

    Ilmunud ka: Lääne Elu, 26. mai 2007, lk. 2; Nädaline, 26. mai 2007, lk. 2; Järva Teataja, 26. mai 2007, lk. 2; Koit, 26. mai 2007, lk. 6; Võrumaa Teataja, 26. mai 2007, lk. 2; Valgamaalane, 29. mai 2007, lk. 2; Vooremaa, 29. mai 2007, lk. 2; Oma Saar, 31. mai 2007, lk. 5; Sakala, 1. juuni 2007, lk. 2; Vali Uudised, 29. juuni 2007, lk. 2. Parlamendiliikme sõnul tuleks praegune ühetasandiline haldussüsteem Eestis säilitada, samuti peab ta oluliseks maakondliku identiteedi hoidmist

  8. Contamination by human fingers. The Midas touch

    International Nuclear Information System (INIS)

    Gwozdz, R.; Grass, F.

    2004-01-01

    Anthropogenic activity is one of the causes of contamination in the human environment: contamination of air, water, top soils, plants and food products has complex effects on human health problems. Wear and abrasion of various surfaces are constant processes in daily life, and commonly include interaction between human fingers and surfaces of every conceivable material. New methods for investigation of trace transfer processes by human fingers are described. Results of transfer for commonly used metals such as gold, silver, zinc, cadmium, tin, cobalt, nickel, chromium and iron are presented. Relationship between transfer of metals by touch and the general problem of purity in analytical activities is briefly discussed. (author)

  9. Mida ootab lugejalt raamatukoguhoidja? / Olga Einasto

    Index Scriptorium Estoniae

    Einasto, Olga, 1965-

    2008-01-01

    Eesti ülikooli- ja linnaraamatukogude töötajate seas läbi viidud küsitluse tulemustest: millised ootused on lugejatele, milliseid lugejaid on meeldiv teenindada, milliseid lugejate omadusi peetakse oluliseks jne

  10. Mida jahvatab Hamleti veski? / Heino Eelsalu

    Index Scriptorium Estoniae

    Eelsalu, Heino, 1930-1998

    1995-01-01

    Rets rmt.: Santilanna, Giorgo de; Dechend, Herta von. Die Mühle des Hamlet : Eine Essay über Mythos und das Gerüst der Zeit. Berlin : Kammerer & Unverzagt, 1993. X, 522 s. (Computerkultur; Band VIII)

  11. Mida hakata peale maamaksuga? / Eugen Veges

    Index Scriptorium Estoniae

    Veges, Eugen, 1955-

    2008-01-01

    Maamaksu kehtestamisest. Ilmunud ka Põhjarannik 17. aprill 2008, lk. 4, pealkiri kujul: kodudelt maamaksu kogumine tuleb lõpetada ; Harju Ekspress 25. aprill 2008, lk. 6, pealkiri kujul: maamaksust...

  12. Mida sportijad vajavad? / Evelin Kivilo-Paas

    Index Scriptorium Estoniae

    Kivilo-Paas, Evelin, 1979-

    2015-01-01

    Sportijate toitainete vajaduse kohta jagavad selgitusi Tallinna Ülikooli terviseteaduste ja spordi instituudi direktor ja spordibioloog Kristjan Port, Synlab Eesti laboriarst dr Anneli Raave-Sepp ja Spordimeditsiini SA spordiarst dr Krista Veevo

  13. Mida lugeja raamatukogult tegelikult ootab / Ene Riet

    Index Scriptorium Estoniae

    Riet, Ene, 1954-

    2011-01-01

    4. teadus- ja erialaraamatukogude päev toimus 21. oktoobril 2011 Eesti Muusika- ja Teatriakadeemias. Teadusraamatukogu aasta teo auhinna pälvis Urmas Sinisalu tulemusliku ja innovaatilise töö eest raamatukogude infosüsteemi ESTER arendamisel. Erialaraamatukogu aasta teo auhinna sai TÜ ajakirjanduse ja kommunikatsiooni instituudi raamatukoguhoidja Maio Vaniko raamatukogundust arendava tegevuse eest

  14. Midas® Fumigant Safe Handling Guide

    Science.gov (United States)

    Handlers or applicators should wear personal protective equipment including respirator and chemical-resistant gloves when working with this soil fumigant, be trained according to the Worker Protection Standard (WPS), and know signs of pesticide exposure.

  15. A Remote Registration Based on MIDAS

    Science.gov (United States)

    JIN, Xin

    2017-04-01

    We often need for software registration to protect the interests of the software developers. This article narrated one kind of software long-distance registration technology. The registration method is: place the registration information in a database table, after the procedure starts in check table registration information, if it has registered then the procedure may the normal operation; Otherwise, the customer must input the sequence number and registers through the network on the long-distance server. If it registers successfully, then records the registration information in the database table. This remote registration method can protect the rights of software developers.

  16. Mida teada uutest RTJidest / Monika Peetson

    Index Scriptorium Estoniae

    Peetson, Monika, 1976-

    2018-01-01

    Rahandusministri 22. detsembri 2017 määrusega jõustunud värksendatud Raamatupidamise Toimkonna Juhenditest (RTJ), mis on rakendadavad 1. jaanuaril 2017 või hiljem alanud aruandeperioodidele. Lisatud vastavad juhendid

  17. Kohtumine, mida Kreml igatseb / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2009-01-01

    Eelseisvast USA presidendi Barack Obama ja Venemaa presidendi Dmitri Medvedevi kohtumisest Londonis G20 tippkohtumise eel, kus tõenäoliselt arutatakse võimalusi kahe suurriigi omavaheliste suhete parandamiseks ning majanduskriisi ületamiseks

  18. MIDA TEEB TEGEMA-VERB HOIDJAKEELES

    Directory of Open Access Journals (Sweden)

    Reili Argus

    2010-01-01

    Full Text Available Esimese keele omandamist mõjutab lapsele suunatud keel ehk hoidjakeel, mis pakub lapsele loomuliku keele sellise statistilise struktuuri, kus tõuseb esile mingi keelesüsteemiosa kõige sagedasem, üldisem, prototüüpsem, kesksem ning kõige lihtsam element. Hoidjakeeles esineb teistest verbidest sagedamini verbi tegema. Selle verbi ühendite hulk ja laad muutub lapse kasvades. Üldjoontes võib tegema-verbi tugiverbi konstruktsioonid lapsele suunatud kõnes jaotada kolme suuremasse rühma: kõige enam esineb selliseid ühendeid, kus tegema verbiga esineb koos mõni onomatopoeetiline sõna; tegema-verbi ja adverbi või adjektiivi ühendeid, millega rõhutatakse teelisust,leidub mõnevõrra vähem ning umbes neljandiku moodustavad tegema-verbi ja noomeni ühendid. Püsiühendite ja rutiniseerunud mallide suur hulk (moodustavad lapsele suunatud kõnes tegema-verbi konstruktsioonidest peaaegu poole annab alust oletada, et lapsega kõneleja eelistab kasutada n-ö valmis kujul keeletükke. Kuigi tegema-verbil on oma roll nii leksika kui ka süntaksi omandamises, ilmneb tema olulisus kõige selgemalt vormimoodustuse omandamise kontekstis: just sellest verbist esineb lapsele suunatud kõnes kõige enam eri vorme ning just see on üks kahest varakult omandatud vormimoodustusega verbe ka lapse kõnes.

  19. Prezident Estonii posjagajet na rol MIDa?

    Index Scriptorium Estoniae

    2001-01-01

    Ilmunud ka Narvskaja Gazeta : Subbotnik (2001/Oct/12) lk. 2. Pealk. ajalehes Molodjozh Estonii (2001/Oct/12) lk. 2: "U prezidenta svoi MID". President Arnold Rüütli otsusest koondada enda ümber välispoliitika asjatundjatest nõukogu

  20. Mida ihkab mu hing? / Toomas Raudam

    Index Scriptorium Estoniae

    Raudam, Toomas, 1947-

    2003-01-01

    Arvustus: Joyce, James. Pagulased : [näidend] / tõlkinud Jaak Rähesoo. Tallinn : Varrak, 2003. Ilmunud ka: Raudam, Toomas. Väike äratundmiste raamat. Tallinn : Eesti Keele Sihtasutus, 2006. Lk. 124-128

  1. Aed, mida pole kunagi kastetud / Kaja Kurg

    Index Scriptorium Estoniae

    Kurg, Kaja, 1959-

    2008-01-01

    Inglise aednikust Beth Chatto'st (sünd. 1923), tema Essexisse rajatud kruusaaiast, mille teevad lopsakaks ja värvikaks kasvupaika sobivad taimed. Lühidalt ülejäänud aiast: vee-, metsa-, alpi- ja taimeaiast. Lk. 72: Beth Chatto kiri Christopher Lloydile (Dear Friend & Gardener : Letters of Life and Gardening, London : Frances Lincoln, 1998), mille on tõlkinud Jaan Mettik

  2. Mida lapsevanem koolilt ootab? / Eda Heinla

    Index Scriptorium Estoniae

    Heinla, Eda

    1999-01-01

    Artikkel põhineb uurimusel, mille eesmärgiks oli saada ülavaade lapsevanemate ootustest koolikeskkonnale kui laste oskuste kujundajale ja loovate võimete arendajale, aluseks elanikkonna küsitlus "Eesti 1998"

  3. Mida õpetab Argentina finantskriis? / Karsten Staehr

    Index Scriptorium Estoniae

    Staehr, Karsten, 1962-

    2002-01-01

    Norra majandusanalüütik kirjeldab Argentina majanduspoliitikat, analüüsib tehtud vigu ning hoiatab avatud majandusega Eestit võimalike tulevaste välisshokkide eest. Diagramm: SKP kasv ja üleüldine riigieelarve tasakaal 1991-2001 Argentinas

  4. Gordon Brown lubab valijal riigieelarvet ümber teha / Siim Trumm

    Index Scriptorium Estoniae

    Trumm, Siim

    2007-01-01

    Peaminister Gordon Brown kavandab mitmeid reforme, et viia riigivõim rahvale lähemale. Inglismaa kümne piirkonna inimestele antakse võimalus otsustada rahvahääletuse kaudu kohaliku eelarve jaotamise üle. Lisa: Browni ja leiboristide toetus kasvab

  5. iPhone'i peab saama lukust lahti teha / Dannar Leitmaa

    Index Scriptorium Estoniae

    Leitmaa, Dannar, 1982-

    2008-01-01

    Kuigi Euroopa Liidu direktiivi kohaselt peab mobiiltelefoni omanikul olema võimalus telefoni lukustusest avada, näeb iPhone'i tootva Apple'i ärimudel ette iPhone'i ostmist ühelt operaatorilt. iPhone 3G telefonide ametlik maaletooja Eestis on EMT, kes pakub neid müügiks kahes erinevas hinnapaketis. Lisa: Juba öösel seisti pikas järjekorras

  6. Kuningas loodab teha kirgliku lavastuse : "Jevgeni Oneginist" saab Eesti ja Soome ooperikoolituse alustala

    Index Scriptorium Estoniae

    2002-01-01

    Sibeliuse akadeemia ja Eesti muusikaakadeemia lauluosakonna juhatajad allkirjastasid ühiste kavatsuste protokolli, mille kohaselt tuuakse ühiste jõududega välja Pjotr Tshaikovski ooper "Jevgeni Onegin"

  7. "Kõige mugavam oli filmis öötööd teha Carmen Kassil" / Verni Leivak

    Index Scriptorium Estoniae

    Leivak, Verni, 1966-

    2003-01-01

    Lõppesid produtsent Kristian Taska uue mängufilmi "Täna öösel me ei maga" võtted. Lavastab Ilmar Taska, operaatoriks on Istvan Borbas, peaosades Carmen Kass, Peter Franzen; Maria Avdjushko, Priit Võigemast. Esilinastus tuleb 13. veebruaril 2004

  8. Ülo Isberg : Tahtsin midagi Eesti heaks teha / Riho Laurisaar

    Index Scriptorium Estoniae

    Laurisaar, Riho

    2005-01-01

    14. juunil sõitis koos Estpla-11 kergejalaväerühmaga Iraaki koalitsioonivägede (Multinational Corps-Iraq) teavitusosakonna teenistusse reservohvitser Ülo Isberg. Sõjaväeametniku elu- ja teenistuskäigust. Lisa: Ülo Isberg

  9. Volta tehas peitis saksa sõjavangide läkitust / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2002-01-01

    Kunagise Volta suurtehase tsaariaegse peakontori remonditööde käigus tuli päevavalgele kaks ajaloolist kirja, millest vanema olid enam kui pool sajandit tagasi seina taha peitnud II maailmasõjas vangi langenud sakslased

  10. Transferwise ähvardab pankadele Skype´i teha / Tarmo Virki

    Index Scriptorium Estoniae

    Virki, Tarmo

    2013-01-01

    Transferwise on kahe tegevusaasta jooksul pankade ülitulusast ärist haaranud 4,5 miljonit dollarit. Nad viisid rahvusvahelised rahaülekanded täielikult internetti ja pakuvad teenust kommertspankadest üle 90 protsendi odavamalt

  11. Verheugen tahab EL-ist teha arvestava kosmosejõu / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2007-01-01

    Euroopa Komisjoni tööstusvolinik Günter Verheugen peab oluliseks ühiseid suuri kosmoseprojekte. Ekspertide koosolekust Münchenis, kus arutati EL-i ühise globaalse keskkonna- ja julgeolekuvalve (GMES) arendamist

  12. Võtkem ohjad enda kätte, tulevik on meie teha / Maria Goltsman

    Index Scriptorium Estoniae

    Goltsman, Maria

    2011-01-01

    Baltimaade nüüdistantsu seminarist Tallinnas 26. - 28. novembrini 2010 pealkirjaga "Taking Matters into Your Own Hands from an Idea to a Project", mis oli osa suurest rahvusvahelisest Keðja projektist (Põhjamaade ja Baltimaade tantsuinimeste võrgustik)

  13. Sul on miljoni dollari idee? Nemad aitavad sul selle rahaks teha / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2010-01-01

    Eesti kultuurivahendajatest, nende nappusest. Kultuurikorraldusest, loomest ja ettevõtlusest, kultuuriturundusest, loomemajandusest, mänedžeri ja looja koostööst, kultuuri ekspordist. Kultuurikorraldajate koolitusest Tartu Ülikoolis ning Eesti Muusika- ja Teatriakadeemias. Arvamust avaldavad galerist Olga Temnikova, Eesti Disainerite Liidu esimees Ilona Gurjanova, kontserdikorraldaja Helen Sildna, Ville Jehe disainibüroost Keha3, Von Krahli Teatri projektijuht Elo-Liis Parmas, moekorraldaja Merilyn Kesküla jt.

  14. Laval võib teha kõike, ainult mitte valetada / Aare Toikka

    Index Scriptorium Estoniae

    Toikka, Aare

    1999-01-01

    Saksamaa teatribiennaal "Augenblick mal" Berliinis ja ASSITEJ 13. maailmakongress ning festival Tromsø's Norramaal. ASSITEJ Eesti Keskuse delegaatidena osalesid Ivo Eensalu ja Mart Kampus. Eestit esindas festivalil VAT Teatri lavastus "Tuudur, Plutt ja Magdaleena". Juttu lasteteatritest Saksamaal (GRIPS Teater, Halle nukuteater, Theater Junge Generation Dresdenist, Neubrandenburgi Kammerteater), Taanis (Paraply-teater, teatritrupp "Batida", Egnsteatret Gruppe 38), Hollandis (Teater "Artemis"), Rootsis (Unga Klara teatrikompanii Stockholmi Linnateatri juures) ja Austraalias (Zeal Theater)

  15. Moskva tehas nõuab Eesti firmalt kohtu kaudu võlga sisse / Niina Voropajeva

    Index Scriptorium Estoniae

    Voropajeva, Niina

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 2. aug. lk. 4. Moskva arbitraazhikohus mõistis Narva firmalt Alekor Textil võõra raha kasutamisest tekkinud võlgnevuse ja võlaprotsentide katteks välja rohkem kui 18 000 dollarit

  16. Aigars Grauba : filmi "Riia kaitsjad" polnud kerge teha / Aigars Grauba ; interv. Kristiina Davidjants

    Index Scriptorium Estoniae

    Grauba, Aigars

    2007-01-01

    Läti režissöör oma mängufilmist "Riia kaitsjad", mis käsitleb lätlaste 1919.a. novembrikuu lahingut Riia pärast Saksa ja Vene väe vastu (produtsent Andrejs Ekis). Filmi näidati eile Balti filmiturul Baltic Event Tallinnas

  17. Valime uue juhatuse ... Kas teha siis juba SE ka ära? / Hannes Vallikivi

    Index Scriptorium Estoniae

    Vallikivi, Hannes, 1974-

    2007-01-01

    Suurfirmade Euroopa äriühinguks ümberkujundamise võitudest ja kaotustest. Lisatud: Eestis asutati esimene Euroopa äriühing ; millised on Euroopa äriühingu eelised? ; mis on Euroopa äriühing ehk Societas Europea? ; neli võimalust Euroopa äriühingu loomiseks ; olulised regulatsioonid

  18. Puudega inimesed tahavad tööd teha / Mike Buckley

    Index Scriptorium Estoniae

    Buckley, Mike

    2003-01-01

    PHARE nõuniku Mike Buckley hinnangul kipuvad toetuste- ja pensionisüsteemid eeldama, et puudega inimesed ei ole suutelised töötama, samas näitavad küsitlused, et kolmandik neist sooviks töötada

  19. Ahtme tehas ehitas töötajatele elamu / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 31. juuli 2004, lk. 1, 3; Postimees, 2. aug. 2004, lk. 9, lüh. Ahtme vagunikoostetehas UVZ & AVR juhid usuvad, et korter motiveerib spetsialiste tehases pikemalt töötama

  20. Uued omanikud tahavad Revinost näidisfarmi teha / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 9. jaan. 2004, lk. 4. Investeerimispank Trigon Capital omandas enamusosaluse osaühingus Revino. Pank kavatseb põllumajandusettevõttest kujundada näidisfarmi, mis aitaks muuta Eesti põllumajandust välisinvestoritele atraktiivsemaks Vt. samas lühiint. Kalev Mae, Ken Noble ja Joakim Heleniusega

  1. Tiina Tammetalu : Eesti maastikud, personifitseeritud, dokumenteeritud = Estonian landscapes, personified, documented / Andreas Trossek

    Index Scriptorium Estoniae

    Trossek, Andreas, 1980-

    2007-01-01

    Maalikunstnik Tiina Tammetalu käsitluses on Eesti maastik dokument, mida ta oma lõuenditel seeriapäraselt rekonstrueerib. 1980-ndate õpiaja maalides kandvaks muutunud kehaesteetika on kunstniku viinud läbi 90-ndate erinevate dokumentaalsete/feministlike näituseprojektide ja kolmemõõtmeliste installatsioonide ideeni, et maastik on kui kunstniku identiteet, on kui keha, on kui mälu. Viimaste aastate töödes aimub kogu seda "eestlaslikku" valulikku ajalootunnetust, need on otsekui retooriliseks vastuseks paljude jaoks korduvale küsimusele - kust oled sa tulnud?

  2. Muutustest maanaiste stereotüüpses kuvandis Eesti naisteajakirjade põhjal / Ell Vahtramäe

    Index Scriptorium Estoniae

    Vahtramäe, Ell, 1966-

    2013-01-01

    Mida kätkeb endas sõnapaar „Eesti maanaine“, milliseid vahendeid vastava stereotüübi kujundamisel on ajakirjanduses kasutatud, kas ja kuidas on stereotüübid muutunud ning millised on nende kontekstid. Allikatena analüüsitakse ajakirjade Taluperenaine ja Eesti Naine (1952-1988 Nõukogude Naine) üksikuid aastakäike. Nendes avaldatu põhjal sünteesitakse maanaise nn ametlik või ideaalne kuvand ning suhestatakse seda reaalse maaeluga

  3. Tee teistele head, kuid tee seda hästi / Jeff Skoll ; interv. Des Dearlove

    Index Scriptorium Estoniae

    Skoll, Jeff

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti : Karjera i obutshenije, 18. aug. 2004, lk. 6-7. Ameerika interneti-oksjonifirma eBay rajaja Jeff Skoll selgitab oma ettevõtte näitel sotsiaalse ettevõtluse olemust ning prognoosib selle populaarsuse kasvu tulevikus

  4. Punase koolimaja saamisloost ning ajast enne ja pärast seda / Aavo Soopa

    Index Scriptorium Estoniae

    Soopa, Aavo

    1998-01-01

    Viljandi Maagümnaasiumi 120. aastapäeval meenutatakse G.M. Schmidti eraõppeasutust ja selle järglase Liivimaa Maagümnaasiumi sündi ja tegevust : ka Riia arhitekti R. Häuseri projekteeritud kahekorruselisest punasest tellismajast, mis valmis 1877.a.

  5. Filmiarhiivid karjuvad, aga seda kuulevad vähesed / Ivi Tomingas ; interv. Tarmo Teder

    Index Scriptorium Estoniae

    Tomingas, Ivi

    2008-01-01

    Vestlusringis, mille teemadeks on filmide digiteerimine, restaureerimine, arhiveerimine, säilitamine ja demonstreerimine, arutlevad Eesti Filmiarhiivi direktor I. Tomingas, Eesti Rahvusringhäälingu filmiarhiivi vastutav toimetaja K. Kanter, "Eesti film 100" projektijuht A. Koppel, ERR arendusjuht H. Männik, Balti Filmi- ja Meediakooli arendusjuht M. Aadamsoo, filmimees E. Säde ja filmiajakirjanik J. Lõhmus

  6. Vanemveebel Korol võib ihunuhtlusest pääseda / Aleksei Günter

    Index Scriptorium Estoniae

    Günter, Aleksei, 1979-

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 7. apr. lk. 5. Araabia Ühendemiraatides naispolitseiniku ahistamise ja alkoholi tarvitamise eest süüdi mõistetud Eesti sõjaväelase Andrei Koroli advokaat Hesham al Nawsan esitas kohtule apellatsiooni, uus kohtuistung toimub 8. aprillil

  7. TEMPERATURA E SUBSTRATO NA GERMINAÇÃO DE SEMENTES DE FLOR-DE-SEDA

    Directory of Open Access Journals (Sweden)

    José Robson da Silva

    2009-01-01

    Full Text Available Silk flower [Calotropis procera (Aiton R. Br.] is a very common plant in the north-eastern Brazil, used in the animal ration in the period of food scarcity, beyond presenting phytotherapic properties and effect presented against nematoid when incorporated to the ground. The work was considered to evaluate the influence of the substrate and the temperature on the germination of seeds and the development of the seedlings. The knowledge on the germination and the more adjusted substrate can propitiate an increment in the production of seedling of silk flower. The temperature can cause changes in the germination percentage, in the speed and relative frequency of germination. In laboratory experiment using the entirely randomized delineation in array factorial 3 x 3, with 4 repetitions, whose plots had been constituted by 25 seeds. The treatments had been to the combinations of three substrate (paper towel, sand and vermiculite with three temperatures, 25 ºC (bookshelf coated with plastic canvas, 27 ºC (laboratory environment, 30º C (chamber of controlled temperature. The analyzed variable had been the percentage of germination, VIG, SDM and height dry of the seedlings. Paper towel, under temperatures 27 and 30 °C, showed it more appropriate for the germination five days after the sowing. Sand and vermiculite under temperatures 25 and 27 ºC, showed it more appropriate for the germination and the index of speed of germination twelve days after the sowing. The dry matter of the seedlings, on sand and vermiculite was superior under temperature 30 ºC.

  8. I have a dream - kõik peavad seda uskuma / Aune Past

    Index Scriptorium Estoniae

    Past, Aune, 1954-

    2004-01-01

    Autori hinnangul ei tohiks ettevõtted maine kujundamiseks ja töötajate lojaalsuse ning rahulolu saavutamiseks loota reklaami-, turundus- või suhtekorraldusfirmadele, kuna mainetloovad väärtused peavad tulema pikaajalise töö tulemusena ettevõtte seest

  9. O papel do Odontopediatra na sedação inalatória consciente

    OpenAIRE

    Loureiro, Dina Lage Valério

    2014-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Ao longo da monografia são abordados vários temas como a anatomofisiologia do paciente infantil, os efeitos dos vários sistemas do corpo humano ao protóxido de azoto, suas indicações e contraindicações e as várias associações farmacológicas com o protóxido de azoto. São também apresentados alguns dos acidentes que podem ser causados ...

  10. Technical Guidelines on Performing a Sediment Erosion and Deposition Assessment (SEDA) at Superfund Sites

    Science.gov (United States)

    2014-09-01

    introduced to a water body because of the failure of a river bank due to, for example, flow-induced erosion of the bank toe and/or surface, or...under supercritical flows (with Froude number greater than one). Antidunes are usually more symmetrical (in their longitudinal profile) than dunes ... dunes , and anti- dunes . Bedload Sediment material moving on top of or near a channel bed by rolling, sliding, and saltating, i.e., jumping

  11. Del Ponte : kurjategijad ei tohi kohtuta pääseda / Liisi Poll

    Index Scriptorium Estoniae

    Poll, Liisi, 1980-

    2006-01-01

    Riigikogu korraldatud Euroopa konverentsil "Väärtused ja huvid rahvusvahelises poliitikas" viibinud endise Jugoslaavia sõjakuritegusid uuriva Haagi rahvusvahelise tribunali peasüüdistaja Carla del Ponte kinnitas, et Euroopa Liidu toetus Haagi tribunalile on ülioluline ja serblastest sõjakurjategijad Radovan Karadzic ja Ratko Mladic peaksid jõudma Haagi kohtu ette. Lisa: Haagi tribunal

  12. Tahad pääseda ajateenistusest? Hakka mõneks aastaks naiseks! / Marvel Riik

    Index Scriptorium Estoniae

    Riik, Marvel

    2016-01-01

    Siseministeerium tahab muuta soovahetuse senisest mugavamaks, see võib aga suurendada soovahetusoperatsiooni läbi teinud noormeeste võimalusi ajateenistusest kõrvale hoida, sest kaitseväeteenistus ei ole naistele kohustuslik

  13. "Isegi pankrotis Kreeka ei kaotanud politseinike eripensione, miks meie siis ometi seda teeme?" / Marvel Riik

    Index Scriptorium Estoniae

    Riik, Marvel

    2016-01-01

    Valitsus otsustas kaotada alates 2020. aastast kaitseväe, prokuröride, politsei ja piirivalveametnike eripensionid. Arvamust avaldavad reservkolonelleitnant Leo Kunnas ja ekspolitseinik Aivar Toompere

  14. IAS 36. Varade väärtuse langus. Kuidas seda arvestada? / Veronika Tugo

    Index Scriptorium Estoniae

    Tugo, Veronika

    2011-01-01

    Rahvusvahelise finantsarvestuse standard IAS 36 määrab kindlaks vara väärtuse languse arvestuse reeglid ja kajastamise etapid. Raha genereerivad üksused, vara väärtuse langus ja sellest tuleneva kahjumi tühistamine

  15. Voces de seda. Las pinturas clandestinas de Agustín Ibarrola (1962-1965

    Directory of Open Access Journals (Sweden)

    de Haro García, Noemi

    2016-09-01

    Full Text Available During his imprisonment in the Prison of Burgos between 1962 and 1965 the artist Agustín Ibarrola clandestinely painted critical artworks. These paintings were exhibited in Spain, but notably in several European countries where they were part of protest movements against the dictatorship. This paper gathers unpublished information in order to study these exhibitions. Special attention is devoted to the solidarity network that supported and made these exhibitions possible, as well as to the reactions they provoked in the control and repression systems of the Franco regime.Durante su encarcelamiento en el Penal de Burgos entre 1962 y 1965 el artista Agustín Ibarrola pintó obras críticas de forma clandestina. Éstas fueron expuestas en España pero, sobre todo, en varios países europeos apoyando las protestas contra la dictadura. Este artículo se basa en documentación inédita para estudiar dichas exposiciones. Se dedica especial atención a la red de solidaridad y apoyo que hizo posible estas exposiciones así como a la reacción ante ellas por parte de los sistemas de control y represión del franquismo.

  16. H-Seda: Partial Packet Recovery with Heterogeneous Block Sizes for Wireless Sensor Networks

    KAUST Repository

    Meer, Ammar M.

    2012-01-01

    . Maximizing bandwidth utilization while maintaining low frame error rate has been an interesting problem. Frame fragmentation into small blocks with dedicated error detection codes per block can reduce the unnecessary retransmission of the correctly received

  17. Iraanil tekkis lootus pääseda Moskva abiga sanktsioonidest / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2006-01-01

    IAEA juht Mohamed ElBaradei loodab jõuda Iraani tuumaprogrammi asjus kokkuleppele, samas ei suuda ta endiselt hinnata, kas Iraani tuumaprogrammi võib pidada rahumeelseks või mitte. Saksamaa, Prantsusmaa ja Suurbritannia lükkasid tagasi Iraani ettepaneku kehtestada tööstuslikule uraanirikastamisele 2-aastane moratoorium, soovides peatada rikastamine 10 aastaks. Lisa: USA ähvardab sõjalise löögiga

  18. Poliitikud vajavad kaastunnet, aga seda ei tohi anda tasuta / Mohamed A. El-Erian

    Index Scriptorium Estoniae

    El-Erian, Mohamed A.

    2011-01-01

    Euroopas, USA-s ja Jaapanis on majanduses valitsev meeleolu uuesti halvenemas, kõik need piirkonnad on hädas võlgade vähendamisega. Poliitikud seisavad praegu silmitsi ebatavaliselt raskete väljakutsetega, me peaksime neid muutusteks survestama

  19. Tehas välistab eestlaste versiooni kopteriõnnetuse põhjuse kohta / Ingvar Bärenklau

    Index Scriptorium Estoniae

    Bärenklau, Ingvar, 1967-

    2006-01-01

    USA helikopteritootja Sikorsky Aircraft lükkab ümber Copterline'i lennuõnnetuse uurimiskomisjoni versiooni, mille järgi Sikorsky S-76 C+ tüüpi kopteri allakukkumise põhjustas pearootori hüdrovõimendi rike. Lisa: Kopteriõnnetus ja uurimine. Vt. samas: Tõnu Ader: me tõestame oma versiooni

  20. Karzai nõuab USA-lt võitu, ähvardades muidu rahu teha / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Afganistani president Hamid Karzai nõuab USA-lt ajakava selle kohta, millal NATO kavatseb Talibani üle võidu saavutada. Afganistanis visiidil viibinud USA president George W. Bush avaldas toetust Barack Obama kavale keskenduda veelgi enam Afganistanis sõdimisele

  1. Mobiilne töötaja võib tööd teha isegi pargipingil / Alar Pardla

    Index Scriptorium Estoniae

    Pardla, Alar, 1970-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 8. sept. lk. 21. GPRS-i ja WiFi kasutajaid puudutavatest turvalisuse ja maksumuse küsimustest. Tabel: GPRS-andmeside hind erineb kuni 20 korda; WiFi-teenuse hindu on raske võrrelda. Vt. samas: Ka Motorola hakkab WiFi-mobiiltelefone tootma. Lisa: Nipid, kuidas mobiilne e-posti kasutaja saab kulusid kokku hoida; Neli kulutust kontori mobiilsemaks muutmisel

  2. Juhan Parts : "Panus tuleks teha tipptehnoloogiale ja koostööle teadlastega" / Juhan Parts ; interv. Riina Mägi

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2007-01-01

    Jõgevamaal visiidil viibinud majandusminister Juhan Parts ettevõtete Valmeco ja Werol Tehased külastusest ja seal nähtust, Venemaa puidutarnetest, Eesti metsanduspoliitikast, Tallinn-Tartu maantee ehitusest, reisirongiliiklusest, ettevõtluse arengu võimalustest regioonis

  3. IT-teenuste edukas sisseostmine : kas kontrollida või teha koostööd / Adriaan Kik, Aigar Koov

    Index Scriptorium Estoniae

    Kik, Adriaan

    2008-01-01

    Ettevõtete suurim väljakutse on kogenud IT- töötajate nappus ja oma ressursi tõhus kasutamine, IT-teenuste turul takistab sisseostmist teenusepakkujate piiratud hulk. Vt. samas: Eesti ja maailm: IT-teenuste sisseostmine

  4. Edward Lucas: Venemaa loodab suhete "restart´i" teha ka Balti riikidega / Edward Lucas ; intervjueerinud Argo Ideon

    Index Scriptorium Estoniae

    Lucas, Edward

    2010-01-01

    Eesti-Vene suhete arengust, Eesti sisepoliitikast, liitumisest euroga, riigieelarve kärbetest, Euroopa riikide suhtumisest Eestis toimuvasse, diplomaatilisi suhteid käsitlevate dokumentide jõudmisest internetti

  5. Konversatsiooniagendi modelleerimine argumenteerimisdialoogis: suhtlus kui infoseisundite värskendamine

    Directory of Open Access Journals (Sweden)

    Mare Koit

    2012-05-01

    Full Text Available Artiklis modelleeritakse sellist vestlusprotsessi, milles üks osaleja püüab mõjutada teist, et see otsustaks teha teatava tegevuse. Keskendutakse konversatsiooniagendi infoseisundite esitusele ja värskendamisreeglitele, mille rakendamise tulemusel liigub agent suhtluses ühest infoseisundist teise. Infoseisundi koosseisu kuulub partneri mudel, mis koosneb partneri oletatavatest hinnangutest vaadeldava tegevuse erinevatele aspektidele. Partneri mudel muutub suhtluse käigus, vastavalt argumentidele ja vastuargumentidele, mida osalejad esitavad tegevuse tegemise poolt või vastu. Konversatsiooniagendi mudeli praktilise realisatsioonina kavandatakse dialoogsüsteemi, nn suhtlustreenerit. Artiklis arutatakse ka inimestevahelise suhtluse modelleerimise üle, tuues näiteid eestikeelsetest argivestlustest.DOI: http://dx.doi.org/10.5128/ERYa8.07

  6. Vastused küsimustele, mida ei esitata / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2009-01-01

    Pärnu kirjastuse Jumalikud Ilmutused raamatutest: fs. Alasti ja elus (2008) ; Kaus, Jan. Miniatuurid (2009) ; Aru, Toomas F. Tahaks keppi Jääääre saatel, ehk, Georges Charles de Heeckeren d’Anthèsi pihtimus (2009)

  7. Vastused küsimustele, mida ei esitata / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2014-01-01

    Pärnu kirjastuse Jumalikud Ilmutused raamatutest: fs. Alasti ja elus (2008) ; Kaus, Jan. Miniatuurid (2009) ; Aru, Toomas F. Tahaks keppi Jääääre saatel, ehk, Georges Charles de Heeckeren d’Anthèsi pihtimus (2009)

  8. Ökomaterjalid - mida, kuhu ja miks? / Margit Kool

    Index Scriptorium Estoniae

    Kool, Margit

    2008-01-01

    Looduslikud materjalid korteris või eramus, maa- või linnakodus, puu- või kivimajas. Kork, puit, sisal, kookoskuid, mererohust põrandakate, linoleum, savikrohv, lubikrohv, tadelakt, kohupiimavärv, lubivärv, savivärv, puitpaneelid, laudis, tapeet. 11 värv. ill.

  9. Mida arutati Brüsselis / Ülo Kalm

    Index Scriptorium Estoniae

    Kalm, Ülo, 1935-

    2004-01-01

    EL Põllumajandusorganisatsioonide Komitee (COPA), Põllumajanduskoostöö Keskkomitee (COGECA) ja Euroopa Komisjoni piimandusalase töögrupi istungitel 2003. aasta lõpul arutlusel olnud teemadest Eesti esindajate poolt EPKK-le esitatud info põhjal

  10. Mida arutati Brüsselis / Ülo Kalm

    Index Scriptorium Estoniae

    Kalm, Ülo, 1935-

    2004-01-01

    Euroopa Komisjoni (EK) metsanduse töörühma, EL Põllumajandusorganisatsioonide Komitee (COPA) ja Põllumajanduskoostöö Keskkomitee (COGEGA) keskkonna töörühma istungitel ning EK põllumajanduskeskkonna nõuandva komitee koosolekul arutluse all olnud teemadest

  11. Mida arutati Brüsselis / Ülo Kalm

    Index Scriptorium Estoniae

    Kalm, Ülo, 1935-

    2004-01-01

    EL Põllumajandusorganisatsioonide Komitee (COPA) ja Põllumajanduskoostöö Keskkomitee (COGEGA) piimatöögrupi, COPA mahekomisjoni ning Euroopa Komisjoni nõuandva komitee töögrupi istungitel arutluse all olnud teemadest

  12. Mida on oodata majanduslanguse ootajatel / James C Cooper

    Index Scriptorium Estoniae

    Cooper, James C

    2008-01-01

    USA majanduse prognoosimiseks tuleb autori sõnul jälgida nelja majandusnäitajat: iganeljapäevased andmed uute töötuskindlustushüvitise taotluste kohta, ostujuhtide assotsiatsiooni Institute of Supply Management tootmis- ja mittetootmissektori aktiivsusindeksid ning USA tööministeeriumi tööhõivearuanne. Tabel: Praegused andmed võrreldes varasemate majanduslangustega

  13. Mida paljastas nutitelefoni lõhkumine? / Villu Zirnask

    Index Scriptorium Estoniae

    Zirnask, Villu, 1966-

    2011-01-01

    Soome majandusuuringute instituudi teadurid ja elektroonikainsenerid Jyrki Ali-Yrkkö, Petri Rouvinen, Timo Seppälä ja Pekka Ylä-Anttila analüüsisid uuringus "Who Captures Value in Global Supply Chains? Case Nokia N95 Smartphone" nutitelefoni hinnakujundust. Detailihindade, koostehindade ja lõpphinna suhe. Diagramm.

  14. Mida vaadata pimedatel öödel? / Kristiina Davidjants

    Index Scriptorium Estoniae

    Davidjants, Kristiina, 1974-

    2006-01-01

    Lühitutvustused-arvustused 10. Pimedate Ööde Filmifestivali filmidest - "Eravaldus" (rež. Loachim Lafosse ; Belgia - Prantsusmaa), "Mängides ohvrit" (rež. Kirill Serebrennikov ; Venemaa), "Knud Rasmusseni päevikud" (rež. Zacharias Kunuk, Norman Cohn ; Kanada - Taani)

  15. Mida pakub aasta 2007 eakale / Helga Rööpson

    Index Scriptorium Estoniae

    Rööpson, Helga

    2007-01-01

    Järvamaa pensionäride koondise juhatuse esimehe, Eesti pensionäride liidu juhatuse liikme Helga Rööpsoni sõnul tuleks pensionide baasosa suurendada ning kuna viimastel aastatel on kulud eluasemele tõusnud 13,3 ja toidule 7,5%, halveneb ka eakate toimetulek

  16. Mida hakata peale Tallinnaga : Bilbao variant / Harry Liivrand, Tõnu Kaalep

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    1998-01-01

    Hispaania linna Bilbao saamisest turismimekaks, kuna seal on maailma tuntud arhitektide projekteeritud hooneid. S. Calatrava, N. Foster jt. Prahas on F. Gehry pangahoone. Kas Tallinnas peaks sama teed kasutama?

  17. Mida õpetab Georgia sõda / Martin Helme

    Index Scriptorium Estoniae

    Helme, Martin, 1976-

    2008-01-01

    Ilmunud ka: Pärnu Postimees 16. aug. lk. 19. Autori hinnangul tuleks Gruusia konfliktist tehtavatest järeldustest tingituna tugevdada olulisel määral Eesti kaitseväge ja relvastust, Venemaa ründe all olles aga loobuda Lääne nõudest vaherahu nimel tagasi tõmbuda. Samuti tuleks arvestada ka asjaoluga, et kohalik venekeelne kogukond on riigile sisepoliitiliselt suureks ohuks. Autori sõnul on ka Eesti esindatus välismissioonidel ressursside raiskamine ning oma vägede koju toomine tugevdaks riigi kaitsevõimet

  18. Reproductive ageing and conflicting clocks: King Midas' touch.

    Science.gov (United States)

    Daly, Irenee; Bewley, Susan

    2013-12-01

    The population attempting pregnancy and having babies is ageing. Gynaecological and obstetric complications worsen with age. Maternity services are struggling. Increasing rates of infertility and complications are not matched by the marvels in the laboratory. This paper argues that assisted reproduction treatment has had a damaging social impact. Despite its public acclaim, it helps few and fails many more. The assisted reproduction industry could take a new and revolutionary direction towards empowering men to experience pregnancy, producing babies from artificial gametes, with a final goal being the liberation of both women and men from the burdens and dangers of pregnancy through the development of artificial wombs. Copyright © 2013. Published by Elsevier Ltd.

  19. Mida teeb Cattelani koer Taani paviljonis / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-

    2009-01-01

    Põhjamaade (Norra, Rootsi, Soome) ja Taani paviljonis 53. Veneetsia kunstibiennaalil eksponeeritud kunstnike-kuraatorite Michael Elmgreeni ja Ingar Dragseti projektist "Kogujad". Kuraatoritöö auhinna pälvinud paviljoni puhul pöörab autor eelkõige tähelepanu just kahele paviljonile kui tervikule ja võimalikele vaatamisviisidele

  20. Mida kõike inimene eluks vajab? / Arvo Sirendi

    Index Scriptorium Estoniae

    Sirendi, Arvo, 1939-

    2001-01-01

    Järgneb: Videvik, 12. juuli 2001, lk. 5; 19. juuli 2001, lk. 5; 9. aug. 2001, lk. 5; 13. sept. 2001, lk. 5; 20. sept. 2001, lk. 5; 27. sept. 2001, lk. 5; 22. nov. 2001, lk. 5. Inimese vajadustest toimetulekuks. Autor: ERL. Parlamendisaadik

  1. Mida on oodata lähiaastate hariduspoliitikas / Peeter Kreitzberg

    Index Scriptorium Estoniae

    Kreitzberg, Peeter, 1948-2011

    2007-01-01

    Ilmunud ka: Severnoje Poberezhje, 29. mai 2007, lk. 2; Virumaa Teataja, 31. mai 2007, lk. 15; Sakala, 31. mai 2007, lk. 2; Järva Teataja, 31. mai 2007, lk. 2; Harjumaa, 1. juuni 2007, lk. 2; Kuulutaja, 1. juuni 2007, lk. 2; Meie Maa, 1. juuni 2007, lk. 2; Nädalaleht, 1. juuni 2007, lk. 3; Vooremaa, 7. juuni 2007, lk. 2; Sõnumitooja, 13. juuni 2007, lk. 2; Lääne Elu, 16. juuni 2007, lk. 6; Lõunaleht, 21. juuni 2007, lk. 4; Pärnu Postimees, 24. juuli 2007, lk. 15. Riigikogu kultuurikomisjoni esimees Eesti hariduspoliitika eesmärkidest

  2. Mida toob meile uus majandusaasta 2001? / Lembo Tanning

    Index Scriptorium Estoniae

    Tanning, Lembo

    2000-01-01

    Vaadeldakse maailma riikide majandusprognoose. Diagrammid: valitud riikide ja regioonide SKP osakaal 1999; arenenud maade SKP kasv 1982-2001; maailma valitud riikide ja regioonide kogutoodangu ning väliskaubanduse kasv; maailma kaupade ja teenuste ekspordi dünaamika 1982-2001

  3. Parim, mida saab raha eest - hakka Staliniks / Jelena Skulskaja

    Index Scriptorium Estoniae

    Skulskaja, Jelena, 1950-

    2004-01-01

    Vene Kinematografistide Liidu esimehe valimistest. Vassili Aksjonovi romaani "Moskva saaga" ekraniseeringus Stalini rolli kinnitatud Moskva panga omaniku Vladimir Mironovi tööst rolliga. Venemaal on suurenenud huvi ajaloolise isiku, Grigori Rasputini vastu

  4. Kuidas valida, mida tõlkida? / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2006-01-01

    Vajadusest tõlkida eesti keelde läänemaailma vaimlistes sfäärides loetavaid välispoliitika-teemalisi raamatuid, näiteks S. Huntingtoni "Tsivilisatsioonide kokkupõrge" ja R. Kagani "Paradiis ja jõud". Ilmunud ka: Sirp : Diplomaatia 7. okt. 2005 nr. 25, lk. 11

  5. Mida vaadata pimedatel öödel? / Mati Sepping

    Index Scriptorium Estoniae

    Sepping, Mati

    2006-01-01

    Euroopa Filmiakadeemia liige tutvustab kuut filmi - Euroopa 2006.a. parima filmi nominenti, millest viis on ka 10. Pimedate Ööde Filmifestivali kavas : "Tee Guantanamosse", "Tuul, mis sasib odrapõldu", "Hommikusöök Pluutol", "Teiste elu", "Grbavica"

  6. The IOC's Midas Touch: Summer Olympics and City Growth

    OpenAIRE

    Volker Nitsch; Nicolai Wendland

    2013-01-01

    Hosting a mega-event is a costly activity of short duration. Still, cities frequently compete to become host of all types of events. This paper examines the effect of staging the largest and most important sporting event in the world, the Summer Olympic Games, on the host city. Applying a difference-in-differences methodology, we analyze the rates of population growth of Olympic cities, candidate cities and other large cities in host and candidate countries over the period from 1860 to 2010. ...

  7. Mida arvasid väliskülalised ?

    Index Scriptorium Estoniae

    2006-01-01

    Saksa teatrikriitik ja teatripedagoog Manfred Jahnke, Turu Rakenduskõrgkooli Kunstiakadeemia nukukunsti õppetooli juhataja Anna Ivanova-Brashinskaya ja Praha teatri Minor stsenarist ja dramaturg Petra Zamecnikova Eesti laste- ja noorteteatri festivalist "Draamake"

  8. www.kellelt-mida-tellida.ee / Tarieli Koppel

    Index Scriptorium Estoniae

    Koppel, Tarieli

    2006-01-01

    Soovitusi firmade Interneti-kodulehekülgede loomiseks ja kujundamiseks jagavad ALL Web Industry OÜ tegevjuht Mihkel Vabrit, Zone Media OÜ tegevjuht Martti Varik ning Welisa OÜ tegevjuht Mattias Lepp. Lisa: Viis soovitust. Vt. ka lk. 58-59: Internet on surnud, elagu internet

  9. Mida jälgida aastal 2007? / Peeter Koppel

    Index Scriptorium Estoniae

    Koppel, Peeter

    2007-01-01

    Autori hinnangul peaks investor 2007. aastal jälgima Lähis-Idas toimuvaid konflikte, oodatud majanduskasvu, võimendatust globaalses finantssüsteemis, riske nii poliitilisel kui majanduslikul tasandil ning arvestama deflatsioonilise shokiga

  10. Skype'i loojad : teeme, mida tahame! / interv. Kristjan Otsmann

    Index Scriptorium Estoniae

    2007-01-01

    Skype'i loojad Jaan Tallinn, Toivo Annust, Ahti Heinla ja Priit Kasesalu, kes on koondunud investeerimisfirmasse Ambient Sound Investments, ning firma tegevjuht Tauno Tats vastavad küsimustele, mis puudutavad nende raha investeerimist. A. Heinla sõnul ei ole nende investeerimise eesmärk teenida üha rohkem raha, sisuline eesmärk on investeerida tehnoloogiasse, edendada tehnoloogiat kogu maailmas. Kommenteerivad Allan Martinson ja Jüri Kaljundi

  11. The South African commercial abalone Haliotis midae fishery began ...

    African Journals Online (AJOL)

    spamer

    and 20 m deep, and virtually no abalone occur at ... factories were granted processing rights to a fixed percentage of an overall .... behaviour and temporal change in individual and aggre- ... series, is to gain further information through carefully.

  12. MiDAS ENCORE: Randomized Controlled Study Design and Protocol.

    Science.gov (United States)

    Benyamin, Ramsin M; Staats, Peter S

    2015-01-01

    Epidural steroid injections (ESIs) are commonly used for treatment of symptomatic lumbar spinal stenosis (LSS). ESIs are generally administered after failure of conservative therapy. For LSS patients suffering from neurogenic claudication, the mild® procedure provides an alternative to ESIs via minimally invasive lumbar decompression. Both ESIs and mild offer interventional pain treatment options for LSS patients experiencing neurogenic claudication refractory to more conservative therapies. Prospective, multi-center, randomized controlled, clinical study. Twenty-six interventional pain management centers throughout the United States. To compare patient outcomes following treatment with either mild or ESIs in LSS patients with neurogenic claudication and having verified ligamentum flavum hypertrophy. Study participants include Medicare beneficiaries who meet study inclusion/exclusion criteria. Eligible patients will be randomized in a 1:1 ratio to one of 2 treatment arms, mild (treatment group) or ESI (control group). Each study group will include approximately 150 patients who have experienced neurogenic claudication symptoms for ≥ 3 months duration who have failed to respond to physical therapy, home exercise programs, and oral analgesics. Those randomized to mild are prohibited from receiving lumbar ESIs during the study period, while those randomized to ESI may receive ESIs up to 4 times per year. Patient assessments will occur at baseline, 6 months, and one year. An additional assessment will be conducted for the mild patient group at 2 years. The primary efficacy outcome measure is the proportion of Oswestry Disability Index (ODI) responders from baseline to one year follow-up in the treatment group (mild) versus the control group (ESI). ODI responders are defined as those patients achieving the validated Minimal Important Change (MIC) of ≥ 10 point improvement in ODI from baseline to follow-up as a clinically significant efficacy threshold. Secondary efficacy outcome measures include the proportion of Zurich Claudication Questionnaire (ZCQ) and Numeric Pain Rating Scale (NPRS) responders from baseline to follow-up using validated MIC thresholds. Improvement in ZCQ domains of ≥ 0.5 is considered significant, and a Patient Satisfaction score of at least 2.5 represents a satisfied patient. A reduction of ≥ 2 points in NPRS is considered significant pain relief. The primary safety outcome measure is the incidence of device- and/or procedure-related adverse events. Descriptive summaries will be presented by randomized group for all outcome measures at baseline and follow-up time points. Inferential statistical analysis will be conducted to determine significant differences related to functional improvement, pain relief, and safety outcomes. Primary study results will be presented based on one-year follow-up data, with an interim analysis report when 6-month follow-up data become available. Patients are not blinded due to significant differences in treatment protocols between study groups. Also, since neither study arm is focused on treatment of radicular pain, there may be a higher non-responder rate for both groups versus standard of care due to study restrictions on adjunctive pain therapies. This prospective, multi-center, randomized controlled study will provide Level I evidence of the safety and effectiveness of mild versus ESIs in managing neurogenic claudication symptoms in LSS patients.

  13. Relationship between MIDAS, depression, anxiety and alexithymia in migraine patients.

    Science.gov (United States)

    Yalınay Dikmen, Pınar; Onur Aysevener, Elif; Kosak, Seda; Ilgaz Aydınlar, Elif; Sağduyu Kocaman, Ayşe

    2017-11-16

    The co-existence of psychiatric comorbidities with migraine is well known; however, the relationship between alexithymia and migraine has not been persuasively shown yet. The aim of the study was to assess the relationships between migraine-related disability, depression, anxiety and alexithymia. One hundred and forty-five migraine patients (33.18 ± 8.6; 111 females, 34 males), and 50 control subjects (29.06 ± 7.6; 34 females, 16 males) were prospectively enrolled for the study. The participants completed a demographic data form and Migraine Disability Assessment Scale, Beck Depression Inventory, Beck Anxiety Inventory and Toronto Alexithymia Score-20 (TAS-20). All migraine patients were more depressive (p = 0.01) and anxious (p = 0.001) than the healthy subjects. TAS-20 scores of the migraine sufferers and the control group did not indicate alexithymia. The migraine-related disability of all migraine patients was severe (27.84 ± 29.22). Depression and anxiety scores in the migraine patients were highly correlated with each other and TAS-20 (r = 0.485, p = 0.001) and all its subscales in turn: difficulty in identifying (r = 0.435, p < 0.001) and describing feelings (r = 0.451, p = 0.001) and externally oriented thinking (r = 0.302, p = 0.001). Moreover, logistic regression analysis revealed that depression and anxiety predicted alexithymia. Our findings showed a complex relationship between migraine, depression, anxiety and alexithymia. On the other hand, alexithymia apparently was not directly connected to migraine, but its presence could be predicted in migraine patients because of co-morbid depression and anxiety.

  14. Incipient speciation driven by hypertrophied lips in Midas cichlid fishes?

    Science.gov (United States)

    Machado-Schiaffino, Gonzalo; Kautt, Andreas F; Torres-Dowdall, Julian; Baumgarten, Lukas; Henning, Frederico; Meyer, Axel

    2017-04-01

    Sympatric speciation has been debated in evolutionary biology for decades. Although it has gained in acceptance recently, still only a handful of empirical examples are seen as valid (e.g. crater lake cichlids). In this study, we disentangle the role of hypertrophied lips in the repeated adaptive radiations of Nicaraguan crater lake cichlid fish. We assessed the role of disruptive selection and assortative mating during the early stages of divergence and found a functional trade-off in feeding behaviour between thick- and thin-lipped ecotypes, suggesting that this trait is a target of disruptive selection. Thick-lipped fish perform better on nonevasive prey at the cost of a poorer performance on evasive prey. Using enclosures in the wild, we found that thick-lipped fish perform significantly better in rocky than in sandy habitats. We found almost no mixed pairs during two breeding seasons and hence significant assortative mating. Genetic differentiation between ecotypes seems to be related to the time since colonization, being subtle in L. Masaya (1600 generations ago) and absent in the younger L. Apoyeque (<600 generations ago). Genome-wide differentiation between ecotypes was higher in the old source lakes than in the young crater lakes. Our results suggest that hypertrophied lips might be promoting incipient sympatric speciation through divergent selection (ecological divergence in feeding performance) and nonrandom mating (assortative mating) in the young Nicaraguan crater lakes. Nonetheless, further manipulative experiments are needed in order to confirm the role of hypertrophied lips as the main cue for assortative mating. © 2017 John Wiley & Sons Ltd.

  15. EQF kutsehariduses ehk mida me Hollandis õppisime / Anu Vaagen

    Index Scriptorium Estoniae

    Vaagen, Anu, 1971-

    2011-01-01

    Leonardo da Vinci programmi finantseeriva projekti EQF kaudu käisid Luua Metsanduskooli direktor, arendusjuht ja maastikuehituse õpetaja Hollandis kompetentsipõhise õppe ja kooli juhtimise vallas teadmisi omandamas

  16. Mida vaadata pimedatel öödel? / Andres Maimik

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    2006-01-01

    Filmirežissöör ja -kriitik soovitab kolme režissööri, kelle filme näidatakse 10. Pimedate Ööde Filmifestivalil : Alex van Warmerdam (Holland), Michael Winterbottom (Suurbritannia) ja Nuri Bilge Ceylan (Türgi)

  17. Mida teeks tulevane kultuuriminister 500 miljoni krooniga? / interv. Andres Keil

    Index Scriptorium Estoniae

    2007-01-01

    Suuremate erakondade kultuurispetsialistid (kultuuriministrikandidaadid) Urmas Paet, Andres Herkel, Peeter Jalakas, Indrek Saar, Jaak Allik, samuti kultuuriminister Raivo Palmaru vastavad küsimustele, mis on suurimad ohud eesti keele ja rahvuskultuuri säilimisele, milline on kultuuriministeeriumi ja -ministri portfelli staatus praeguses valitsuses, kas kultuuri rahastamine riigieelarvest on piisav, mille poolest erineb nende erakonna nägemus kultuuripoliitikast teiste erakondade omast, kuhu nad suunaksid 50, 500 miljonit, kui see oleks nende käsutuses

  18. Mida mõtlevad tippjuhid? / interv. John A. Byrne

    Index Scriptorium Estoniae

    2008-01-01

    USA majandusliku olukorra ja tulevikuprognooside üle arutlevad FedExi juht Fred Smith, Chrysleri tegevjuht Robert Nardell, endine General Electric'u aseesimees Dennis Dammerman, Caritas Christi Health Care tegevjuht Ralph de la Torre, Abbott Labs tegevjuht Miles White, FPL Group tegevjuht Lewis Hay, BorgWarneri tegevjuht Timothy Manganello ning Schering-Plough tegevjuht Fred Hassan

  19. Mida Adolf Hitler tummfilmis ütles? / Priit Pruul

    Index Scriptorium Estoniae

    Pruul, Priit

    2006-01-01

    Frank Huberi poolt välja töötatud arvuti tarkvara ALR võimaldab Adolf Hitlerist tema mägimajas tehtud tummfilmidest välja lugeda füüreri suuliigutustega edasiantud teksti. (The Daily Telegraphi põhjal)

  20. Mida roheline tarbija tahab / Catherine Roche ; intervjueerinud Michael S. Hopkins

    Index Scriptorium Estoniae

    Roche, Catherine, 1977-

    2009-01-01

    2008. a. tehtud uuringust, mille abil selgitati välja, mis põhjustel inimesed eelistavad tarbimisel rohelist tootevalikut. Skeemid: Valmisolek maksta rohelise eest rohkem sõltub tootekategooriast ja tajutavatest eelistest; Teadlikkus ja valik