WorldWideScience

Sample records for technology project ctp

  1. Ceramic Technology Project database: March 1990 summary report. DOE/ORNL Ceramic Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-07-01

    This report is the fifth in a series of semiannual data summary reports on information being stored in the Ceramic Technology Project (CTP) database. The overall system status as of March 31, 1990, is summarized, and the latest additions of ceramic mechanical properties data are given for zirconia, silicon carbide, and silicon nitride ceramic mechanical properties data, including some properties on brazed specimens.

  2. Ceramic Technology Project database: March 1990 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-07-01

    This report is the fifth in a series of semiannual data summary reports on information being stored in the Ceramic Technology Project (CTP) database. The overall system status as of March 31, 1990, is summarized, and the latest additions of ceramic mechanical properties data are given for zirconia, silicon carbide, and silicon nitride ceramic mechanical properties data, including some properties on brazed specimens.

  3. Ceramic Technology Project database: September 1990 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    Data generated within the Ceramic Technology Project (CTP) represent a valuable resource for both research and industry. The CTP database was created to provide easy access to this information in electronic and hardcopy forms by using a computerized database and by issuing periodic hardcopy reports on the database contents. This report is the sixth in a series of semiannual database summaries and covers recent additions to the database, including joined brazed specimen test data. It covers 1 SiC, 34 SiN, 10 whisker-reinforced SiN, 2 zirconia-toughened aluminas, 8 zirconias, and 34 joints.

  4. CTP limitation increases expression of CTP synthase in Lactococcus lactis

    DEFF Research Database (Denmark)

    Jørgensen, C.M.; Hammer, Karin; Martinussen, Jan

    2003-01-01

    for regulation of the pyrG gene. It is possible to fold the pyrG leader in an alternative structure that would prevent the formation of the terminator. We suggest a model for pyrG regulation in L. lactis, and probably in other gram-positive bacteria as well, in which pyrG expression is directly dependent...... on the CTP concentration through an attenuator mechanism. At normal CTP concentrations a terminator is preferentially formed in the pyrG leader, thereby reducing expression of CTP synthase. At low CTP concentrations the RNA polymerase pauses at a stretch of C residues in the pyrG leader, thereby allowing...

  5. CTP limitation increases expression of CTP synthase in Lactococcus lactis

    DEFF Research Database (Denmark)

    Jørgensen, C.M.; Hammer, Karin; Martinussen, Jan

    2003-01-01

    on the CTP concentration through an attenuator mechanism. At normal CTP concentrations a terminator is preferentially formed in the pyrG leader, thereby reducing expression of CTP synthase. At low CTP concentrations the RNA polymerase pauses at a stretch of C residues in the pyrG leader, thereby allowing......CTP synthase is encoded by the pyrG gene and catalyzes the conversion of UTP to CTP. A Lactococcus lactis pyrG mutant with a cytidine requirement was constructed, in which beta-galactosidase activity in a pyrG-lacLM transcriptional fusion was used to monitor gene expression of pyrG. A 10-fold...... decrease in the CTP pool induced by cytidine limitation was found to immediately increase expression of the L. lactis pyrG gene. The final level of expression of pyrG is 37-fold higher than the uninduced level. CTP limitation has pronounced effects on central cellular metabolism, and both RNA and protein...

  6. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  7. Ceramics Technology Project database: September 1991 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    The piston ring-cylinder liner area of the internal combustion engine must withstand very-high-temperature gradients, highly-corrosive environments, and constant friction. Improving the efficiency in the engine requires ring and cylinder liner materials that can survive this abusive environment and lubricants that resist decomposition at elevated temperatures. Wear and friction tests have been done on many material combinations in environments similar to actual use to find the right materials for the situation. This report covers tribology information produced from 1986 through July 1991 by Battelle columbus Laboratories, Caterpillar Inc., and Cummins Engine Company, Inc. for the Ceramic Technology Project (CTP). All data in this report were taken from the project`s semiannual and bimonthly progress reports and cover base materials, coatings, and lubricants. The data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies, but not to draw conclusions from these data.

  8. Ceramic Technology Project data base: September 1992 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1993-06-01

    Data presented in this report represent an intense effort to improve processing methods, testing methods, and general mechanical properties (rupture modulus, tensile, creep, stress-rupture, dynamic and cyclic fatigue, fracture toughness) of candidate ceramics for use in advanced heat engines. This work was performed by many facilities and represents only a small part of the data generated by the Ceramic Technology Project (CTP) since 1986. Materials discussed include GTE PY6, GN-10, NT-154, NT-164, SN-260, SN-251, SN-252, AY6, silicon nitride combined with rare-earth oxides, Y-TZP, ZTA, NC-433, NT-230, Hexoloy SA, MgO-PSZ-to-MgO-PSZ joints, MgO-PSZ-to-cast iron, and a few whisker/fiber-reinforced ceramics. Information in this report was taken from the project`s semiannual and bimonthly progress reports and from final reports summarizing the results of individual studies. Test results are presented in tabular form and in graphs. All data, including test rig descriptions and material characterizations, are stored in the CTP data base and are available to all project participants on request. The objective of this report is to make available the test results from these studies but not to draw conclusions from those data.

  9. Ceramic Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The Ceramic Technology Project was developed by the USDOE Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS's Materials Development Program, was developed to meet the ceramic technology requirements of the OTS's automotive technology programs. Significant accomplishments in fabricating ceramic components for the USDOE and NASA advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. These programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and data base and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. A five-year project plan was developed with extensive input from private industry. In July 1990 the original plan was updated through the estimated completion of development in 1993. The objective is to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on the structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines. To facilitate the rapid transfer of this technology to US industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities.

  10. Ceramic Technology Project database: September 1990 summary report. [SiC, SiN, whisker-reinforced SiN, ZrO-toughened aluminas, zirconias, joints

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    Data generated within the Ceramic Technology Project (CTP) represent a valuable resource for both research and industry. The CTP database was created to provide easy access to this information in electronic and hardcopy forms by using a computerized database and by issuing periodic hardcopy reports on the database contents. This report is the sixth in a series of semiannual database summaries and covers recent additions to the database, including joined brazed specimen test data. It covers 1 SiC, 34 SiN, 10 whisker-reinforced SiN, 2 zirconia-toughened aluminas, 8 zirconias, and 34 joints.

  11. Information technology project management

    National Research Council Canada - National Science Library

    Schwalbe, Kathy

    2014-01-01

    ... (IT) projects that extend well beyond standard project management requirements. No book offers more up-to-the minute insights and software tools for IT project management success, including updates that reflect the latest PMBOKʼ...

  12. Information technology project management

    National Research Council Canada - National Science Library

    Schwalbe, Kathy

    2014-01-01

    ... (IT) projects that extend well beyond standard project management requirements. No book offers more up-to-the minute insights and software tools for IT project management success, including updates that reflect the latest PMBOK...

  13. Transformational Tools and Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Transformational Tools and Technologies (TTT) Project advances state-of-the-art computational and experimental tools and technologies that are vital to aviation...

  14. Fundamentals of technology project management

    CERN Document Server

    Garton, Colleen

    2012-01-01

    Designed to provide software engineers, students, and IT professionals with an understanding of the fundamentals of project management in the technology/IT field, this book serves as a practical introduction to the subject. Updated with information on how Fundamentals of Project Management integrates with and complements Project Management Institute''s Project Management Body of Knowledge, this collection explains fundamental methodologies and techniques while also discussing new technology, tools, and virtual work environments. Examples and case studies are based on technology projects, and t

  15. Technology Education Professional Enhancement Project

    Science.gov (United States)

    Hughes, Thomas A., Jr.

    1996-01-01

    The two goals of this project are: the use of integrative field of aerospace technology to enhance the content and instruction delivered by math, science, and technology teachers through the development of a new publication entitled NASA Technology Today, and to develop a rationale and structure for the study of technology, which establishes the foundation for developing technology education standards and programs of the future.

  16. [Earth Science Technology Office's Computational Technologies Project

    Science.gov (United States)

    Fischer, James (Technical Monitor); Merkey, Phillip

    2005-01-01

    This grant supported the effort to characterize the problem domain of the Earth Science Technology Office's Computational Technologies Project, to engage the Beowulf Cluster Computing Community as well as the High Performance Computing Research Community so that we can predict the applicability of said technologies to the scientific community represented by the CT project and formulate long term strategies to provide the computational resources necessary to attain the anticipated scientific objectives of the CT project. Specifically, the goal of the evaluation effort is to use the information gathered over the course of the Round-3 investigations to quantify the trends in scientific expectations, the algorithmic requirements and capabilities of high-performance computers to satisfy this anticipated need.

  17. Additive Manufacturing Technology Development Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The 3D Printing In Zero-G (3D Print) technology demonstration project is a proof-of-concept test designed to assess the properties of melt deposition modeling...

  18. Photonics: Technology project summary

    Science.gov (United States)

    Depaula, Ramon P.

    1991-01-01

    Photonics involves the use of light (photons) in conjunction with electronics for applications in communications, computing, control, and sensing. Components used in photonic systems include lasers, optical detectors, optical wave guide devices, fiber optics, and traditional electronic devices. The goal of this program is to develop hybrid optoelectronic devices and systems for sensing, information processing, communications, and control. It is hoped that these new devices will yield at least an order of magnitude improvement in performance over existing technology. The objective of the program is to conduct research and development in the following areas: (1) materials and devices; (2) networking and computing; (3) optical processing/advanced pattern recognition; and (4) sensing.

  19. Photonics: Technology project summary

    Science.gov (United States)

    Depaula, Ramon P.

    1991-01-01

    Photonics involves the use of light (photons) in conjunction with electronics for applications in communications, computing, control, and sensing. Components used in photonic systems include lasers, optical detectors, optical wave guide devices, fiber optics, and traditional electronic devices. The goal of this program is to develop hybrid optoelectronic devices and systems for sensing, information processing, communications, and control. It is hoped that these new devices will yield at least an order of magnitude improvement in performance over existing technology. The objective of the program is to conduct research and development in the following areas: (1) materials and devices; (2) networking and computing; (3) optical processing/advanced pattern recognition; and (4) sensing.

  20. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Ke-Mian [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193 (China); Chang, Chia-Chun [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Shen, Qing-Ji [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); Sung, Li-Ying, E-mail: liyingsung@ntu.edu.tw [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan, ROC (China); Liu, Ji-Long, E-mail: jilong.liu@dpag.ox.ac.uk [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom)

    2014-04-15

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus.

  1. Iterative Reconstruction Improves Both Objective and Subjective Image Quality in Acute Stroke CTP.

    Directory of Open Access Journals (Sweden)

    Fabian Flottmann

    Full Text Available Computed tomography perfusion (CTP imaging in acute ischemic stroke (AIS suffers from measurement errors due to image noise. The purpose of this study was to investigate if iterative reconstruction (IR algorithms can be used to improve the diagnostic value of standard-dose CTP in AIS.Twenty-three patients with AIS underwent CTP with standardized protocol and dose. Raw data were reconstructed with filtered back projection (FBP and IR with intensity levels 3, 4, 5. Image quality was objectively (quantitative perfusion values, signal-to-noise ratio (SNR, contrast-to-noise ratio (CNR and subjectively (overall image quality assessed. Ischemic core and perfusion mismatch were visually rated. Discriminative power for tissue outcome prediction was determined by the area under the receiver operating characteristic curve (AUC resulting from the overlap between follow-up infarct lesions and stepwise thresholded CTP maps.With increasing levels of IR, objective image quality (SNR and CNR in white matter and gray matter, elimination of error voxels and subjective image quality improved. Using IR, mean transit time (MTT was higher in ischemic lesions, while there was no significant change of cerebral blood volume (CBV and cerebral blood flow (CBF. Visual assessments of perfusion mismatch changed in 4 patients, while the ischemic core remained constant in all cases. Discriminative power for infarct prediction as represented by AUC was not significantly changed in CBV, but increased in CBF and MTT (mean (95% CI: 0.72 (0.67-0.76 vs. 0.74 (0.70-0.78 and 0.65 (0.62-0.67 vs 0.67 (0.64-0.70.In acute stroke patients, IR improves objective and subjective image quality when applied to standard-dose CTP. This adds to the overall confidence of CTP in acute stroke triage.

  2. 热敏CTP与紫激光CTP之争(二)%Thermal CTP vs violet laser CTP

    Institute of Scientific and Technical Information of China (English)

    郑世明; 张志林

    2001-01-01

    @@ 6.爱克发公司的Galileo紫激光CTP (1)爱克发公司的Galileo系列CTP 迄今为止,爱克发公司已开发出一整套的Galileo激光CTP系列产品,该系列包括8种机型,均为内鼓式结构,采用可见绿光、红外或可见紫激光等激光光源,这8种Galileo CTP设备的性能参数,详见表1.

  3. Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis

    DEFF Research Database (Denmark)

    Jørgensen, C.M.; Hammer, Karin; Jensen, Peter Ruhdal;

    2004-01-01

    The pyrG gene from Lactococcus lactis encodes CTP synthase (EC 6.4.3.2), an enzyme converting UTP to CTP. A series of strains were constructed with different levels of pyrG expression by insertion of synthetic constitutive promoters with different strengths in front of pyrG. These strains expressed...

  4. It's TIME for Technology: The Technology in Mathematics Education Project

    Science.gov (United States)

    Hardy, Michael

    2008-01-01

    This article describes the impact that the Technology in Mathematics Education (TIME) Project had on participating middle level and secondary mathematics teachers' preparedness to teach through technology. Results indicate that the TIME Project positively impacted participants' perceptions of their knowledge of technological resources and methods…

  5. The Language Technologies for Lifelong Learning Project

    NARCIS (Netherlands)

    Berlanga, Adriana

    2009-01-01

    Berlanga, A. J. (2009). The Language Technologies for Lifelong Learning Project. Poster presented at the 9th IEEE International Conference on Advanced Learning Technologies (ICALT 2009). July, 15-17, 2009, Riga, Latvia.

  6. A review of CT-P13: an infliximab biosimilar.

    Science.gov (United States)

    McKeage, Kate

    2014-06-01

    CT-P13 (Remsima™; Inflectra™), a biosimilar of reference infliximab (Remicade(®)), is approved by the European Medicines Agency for use in all indications for which reference infliximab is approved, including rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, psoriatic arthritis and psoriasis. Infliximab is a chimeric human-murine monoclonal antibody against the proinflammatory cytokine tumour necrosis factor-α. The CT-P13 infliximab formulation is identical to that of reference infliximab and it has similar physiochemical characteristics. The approval of CT-P13 was based on the results of a rigorous, comparability exercise. This article reviews the results of that exercise, focusing on the clinical evaluation programme. In two well-designed clinical trials, CT-P13 was equivalent to reference infliximab in terms of pharmacokinetic properties in patients with ankylosing spondylitis and in terms of efficacy in patients with rheumatoid arthritis. In both studies, CT-P13 was generally well tolerated with a similar tolerability profile to that of reference infliximab. Immunogenicity evaluations demonstrated that the proportion of patients developing anti-drug antibodies was similar with each agent. Preliminary data from trial extensions demonstrated that in patients who switched from reference infliximab to CT-P13, efficacy was sustained and similar to those who were treated continuously with CT-P13. As with all biosimilar and generic agents, CT-P13 has the potential to reduce treatment costs compared with those of reference infliximab, and modelled analyses predict significant cost savings compared with reference infliximab. In conclusion, CT-P13 is an infliximab biosimilar that provides a useful alternative to reference infliximab in patients requiring infliximab therapy.

  7. Advanced Situation Awareness Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced Situation Awareness Technologies (ASAT) will facilitate exploration of the moon surface, and other planetary bodies. This powerful technology will also find...

  8. Management of Innovative Projects through Agile Technology

    Directory of Open Access Journals (Sweden)

    Radu Bucea-Manea-Tonis

    2014-09-01

    Full Text Available Because of the globalization and the evolution of internet and technologies, nowadays the innovation is associated with open collaboration conducted by a legal framework. The paper analyses the methods that allow a better management for innovative projects and focuses on agile projects within a technological network.

  9. Fabrication of CTP/HAp novel gradient composite bioceramics

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Calcium-titanium-phosphate(CaTi4(PO4)6, CTP)/hydroxyapatite(HAp) is a kind of novel gradient composite bioceramics,which has excellent biocompatibility and bioactivity. CTP ceramic film was synthesized one-step on the surface of titanium using micro-arc oxidation(MAO). The CTP/HAp composite bioceramics were prepared by soaking CTP film in HAp inducing solution for several days. XRD, SEM and EDX were used to characterize the bio-ceramic films phase and composition, morphology and component. The influence of electrolyte molar ratio of Ca to P and the current density to the synthesis of film was studied, and the optimized value of parameters above were 1/6 and 15A/dm2. The parameters of HAp inducing solution, such as component and pH value were also studied and the best pH value which is adjusted by NaOH is 6.4.

  10. The ATLAS Level-1 Central Trigger Processor (CTP)

    CERN Document Server

    Spiwoks, Ralf; Ellis, Nick; Farthouat, P; Gällnö, P; Haller, J; Krasznahorkay, A; Maeno, T; Pauly, T; Pessoa-Lima, H; Resurreccion-Arcas, I; Schuler, G; De Seixas, J M; Torga-Teixeira, R; Wengler, T

    2005-01-01

    The ATLAS Level-1 Central Trigger Processor (CTP) combines information from calorimeter and muon trigger processors and makes the final Level-1 Accept (L1A) decision on the basis of lists of selection criteria (trigger menus). In addition to the event-selection decision, the CTP also provides trigger summary information to the Level-2 trigger and the data acquisition system. It further provides accumulated and bunch-by-bunch scaler data for monitoring of the trigger, detector and beam conditions. The CTP is presented and results are shown from tests with the calorimeter adn muon trigger processors connected to detectors in a particle beam, as well as from stand-alone full-system tests in the laboratory which were used to validate the CTP.

  11. Smart Gun Technology project. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, D.R.

    1996-05-01

    The goal of the Smart Gun Technology project is to eliminate the capability of an unauthorized user form firing a law officer`s firearm by implementing user-recognizing-and-authorizing (or {open_quotes}smart{close_quotes}) surety technologies. This project was funded by the National Institute of Justice. This report lists the findings and results of the project`s three primary objectives. First, to find and document the requirements for a smart firearm technology that law enforcement officers will value. Second, to investigate, evaluate, and prioritize technologies that meet the requirements for a law enforcement officer`s smart firearm. Third, to demonstrate and document the most promising technology`s usefulness in models of a smart firearm.

  12. Methane LIDAR Laser Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Fibertek proposes to develop laser technology intended to meet NASA's need for innovative lidar technologies for atmospheric measurements of methane. NASA and the...

  13. Advanced Situation Awareness Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced Situation Awareness Technologies (ASAT) will facilitate exploration of the moon surface, and other planetary bodies. ASAT will create an Advanced Situation...

  14. Improved hyperspectral imaging technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Improved hyperspectral imaging technologies could enable lower-cost analysis for planetary science including atmospheric studies, mineralogical investigations, and...

  15. Personal projection with Ujoy technology

    Science.gov (United States)

    Moench, Holger; Mackens, Uwe; Pekarski, Pavel; Ritz, Arnd; S'heeren, Griet; Verbeek, Will

    2007-02-01

    Personal projection is a new way to use projectors for gaming, entertainment or photo projection. The requirements for this new category have been defined based on market research with focus groups. A screen brightness of 200-300lm out of compact and affordable devices is a must. In order to reach this performance a very bright light source is at least as important as for professional projectors. The new 50W Ujoy lamp system with 1mm arc enables efficient projection systems. Lower cooling requirements, the potential for battery operation and the low voltage input makes it the ideal source for this new category of projectors.

  16. Causal Models for Safety Assurance Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Fulfillment of NASA's System-Wide Safety and Assurance Technology (SSAT) project at NASA requires leveraging vast amounts of data into actionable knowledge. Models...

  17. Computer Programming Projects in Technology Courses.

    Science.gov (United States)

    Thomas, Charles R.

    1985-01-01

    Discusses programming projects in applied technology courses, examining documentation, formal reports, and implementation. Includes recommendations based on experience with a sophomore machine elements course which provided computers for problem solving exercises. (DH)

  18. Wireless Sensor Portal Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Mobitrum Corporation has demonstrated the feasibility in the Phase I of " A Wireless Sensor Portal Technology" and proposes a Phase II effort to develop a wireless...

  19. Computer Technology in Construction Project Management

    Institute of Scientific and Technical Information of China (English)

    Zhang Zhi

    2014-01-01

    Today, the network information has become a trend al of the industries have to face. For the construction project management, we must fuly master the use of computer information technology, mining its intrinsic value, so that it can promote the construction industry to meet the requirements of the times. This paper demonstrates the main application of computer technology in construction project management in a brief analysis.

  20. Ceramics Technology Project database: September 1991 summary report. [Materials for piston ring-cylinder liner for advanced heat/diesel engines

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    The piston ring-cylinder liner area of the internal combustion engine must withstand very-high-temperature gradients, highly-corrosive environments, and constant friction. Improving the efficiency in the engine requires ring and cylinder liner materials that can survive this abusive environment and lubricants that resist decomposition at elevated temperatures. Wear and friction tests have been done on many material combinations in environments similar to actual use to find the right materials for the situation. This report covers tribology information produced from 1986 through July 1991 by Battelle columbus Laboratories, Caterpillar Inc., and Cummins Engine Company, Inc. for the Ceramic Technology Project (CTP). All data in this report were taken from the project's semiannual and bimonthly progress reports and cover base materials, coatings, and lubricants. The data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies, but not to draw conclusions from these data.

  1. Cost analysis methodology: Photovoltaic Manufacturing Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Whisnant, R.A. (Research Triangle Inst., Research Triangle Park, NC (United States))

    1992-09-01

    This report describes work done under Phase 1 of the Photovoltaic Manufacturing Technology (PVMaT) Project. PVMaT is a five-year project to support the translation of research and development in PV technology into the marketplace. PVMaT, conceived as a DOE/industry partnership, seeks to advanced PV manufacturing technologies, reduce PV module production costs, increase module performance, and expand US commercial production capacities. Under PVMaT, manufacturers will propose specific manufacturing process improvements that may contribute to the goals of the project, which is to lessen the cost, thus hastening entry into the larger scale, grid-connected applications. Phase 1 of the PVMaT project is to identify obstacles and problems associated with manufacturing processes. This report describes the cost analysis methodology required under Phase 1 that will allow subcontractors to be ranked and evaluated during Phase 2.

  2. Ceramic technology for advanced heat engines project

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    The Ceramic Technology for Advanced Heat Engines Project was developed by the Department of Energy's Office of Transportation Systems in Conservation and Renewable Energy. This project was developed to meet the ceramic technology requirements of the OTT's automotive technology programs. This project is managed by ORNL and is closely coordinated with complementary ceramics tasks funded by other DOE offices, NASA, DoD, and industry. Research is discussed under the following topics; Turbomilling of SiC Whiskers; microwave sintering of silicon nitride; and milling characterization; processing of monolithics; silicon nitride matrix; oxide matrix; silicate matrix; thermal and wear coatings; joining; design; contact interfaces; time-dependent behavior; environmental effects; fracture mechanics; nondestructive evaluation; and technology transfer. References, figures, and tables are included with each topic.

  3. Technology Management on Large Construction Projects

    DEFF Research Database (Denmark)

    Bonke, Sten

    The aim of this text is to discuss and to develop the concept of technology management in relation to the empirical field of construction projects. In the first of the two main sections central theories and their derived assertions concerning technology management criteria are summed up...... in a schematic theoretical framework. Hereafter the general characteristics of construction are examined from the point of view of serving as an empirical field for technology management analysis. In the second section the technology management theme is associated with the empirical properties of the Great Belt...... Fixed Link construction project. Finally on this basis the concluding remarks are pointing to the main theoretical problems and their practical implementations for the introduction of a technology management discipline in construction....

  4. Projection display technologies for the new millennium

    Science.gov (United States)

    Kahn, Frederic J.

    2000-04-01

    Although analog CRTs continue to enable most of the world's electronic projection displays such as US consumer rear projection televisions, discrete pixel (digital) active matrix LCD and DLP reflective mirror array projectors have rapidly created large nonconsumer markets--primarily for business. Recent advances in image quality, compactness and cost effectiveness of digital projectors have the potential to revolutionize major consumer and entertainment markets as well. Digital penetration of the mainstream consumer projection TV market will begin in the hear 2000. By 2005 digital projection HDTVs could take the major share of the consumer HDTV projection market. Digital projection is expected to dominate both the consumer HDTV and the cinema market by 2010, resulting in potential shipments for all projection markets exceeding 10 M units per year. Digital projection is improving at a rate 10X faster than analog CRT projectors and 5X faster than PDP flat panels. Continued rapid improvement of digital projection is expected due to its relative immaturity and due to the wide diversity of technological improvements being pursued. Key technology enablers are the imaging panels, light sources and micro-optics. Market shares of single panel projectors, MEMs panels, LCOS panels and low T p-Si TFT LCD panel variants are expected to increase.

  5. Technology integration project: Environmental Restoration Technologies Department Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Williams, C.V.; Burford, T.D. [Sandia National Labs., Albuquerque, NM (United States). Environmental Restoration Technologies; Allen, C.A. [Tech Reps, Inc., Albuquerque, NM (United States)

    1996-08-01

    Sandia National Laboratories Environmental Restoration Technologies Department is developing environmental restoration technologies through funding form the US Department of Energy`s (DOE`s) Office of Science and Technology. Initially, this technology development has been through the Mixed Waste Landfill Integrated Demonstration (MWLID). It is currently being developed through the Contaminant Plume containment and Remediation Focus Area, the Landfill Stabilization Focus Area, and the Characterization, Monitoring, and Sensor Cross-Cutting Program. This Technology Integration Project (TIP) was responsible for transferring MWLID-developed technologies for routine use by environmental restoration groups throughout the DOE complex and commercializing these technologies to the private sector. The MWLID`s technology transfer/commercialization successes were achieved by involving private industry in development, demonstration, and technology transfer/commercialization activities; gathering and disseminating information about MWLID activities and technologies; and promoting stakeholder and regulatory involvement. From FY91 through FY95, 30 Technical Task Plans (TTPs) were funded. From these TTPs, the MWLID can claim 15 technology transfer/commercialization successes. Another seven technology transfer/commercialization successes are expected. With the changeover to the focus areas, the TIP continued the technology transfer/commercialization efforts begun under the MWLID.

  6. Teaching Physics Using Appropriate Technology Projects

    Science.gov (United States)

    Pearce, Joshua M.

    2007-03-01

    Appropriate technologies able to be easily and economically constructed from readily available materials by local craftspeople have a central role in the alleviation of poverty in the developing world. However, research and development of these technologies are generally apportioned relatively modest support by the developed world's institutions, in part because the operation of many of these appropriate technologies is dependent on relatively well-understood science accessible even to introductory college physics students. This paper describes a project-based assignment used to capitalize on this opportunity to motivate students to learn physics by offering them a chance to make concrete contributions to the optimization of appropriate technologies for sustainable development.

  7. Information Technology in Engineering and Project Management

    Directory of Open Access Journals (Sweden)

    Chien-Ho Ko

    2017-01-01

    Full Text Available Information Technology (IT can be regarded as the use of computers to store, analyze, and manipulate data (Daintith, 2009. With the rapid development of personal computers, IT has been widely applied in nearly every field (Davenport, 2013. This issue presents five papers covering engineering and project management, three of which focus on the application of IT to solve engineering and project management issues, while one presents research into public private partnerships, and another into cash flow forecasting.

  8. Project Management for Engineering, Business, and Technology

    CERN Document Server

    Nicholas, John M

    2012-01-01

    There is an ever-growing need for better project management within the disciplines of engineering, business and technology and this new edition is a direct response to that need. By emphasizing practical applications, this book targets the ultimate purpose of project management; to unify and integrate the interests, resources and work efforts of many stakeholders to accomplish the overall project goal. The book encompasses the essential background material, from philosophy to methodology, that is required, before dedicating itself to presenting concepts and techniques of practical application

  9. Ceramic Technology for Advanced Heat Engines Project

    Energy Technology Data Exchange (ETDEWEB)

    1990-08-01

    The Ceramic Technology For Advanced Heat Engines Project was developed by the Department of Energy's Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS's Advanced Materials Development Program, was developed to meet the ceramic technology requirements of the OTS's automotive technology programs. Significant accomplishments in fabricating ceramic components for the Department of Energy (DOE), National Aeronautics and Space Administration (NASA), and Department of Defense (DOD) advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. However, these programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and data base and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. An assessment of needs was completed, and a five year project plan was developed with extensive input from private industry. The objective of the project is to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on structural ceramics for advanced gas turbine and diesel engines, ceramic hearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines.

  10. CT-P13: design, development, and place in therapy

    Directory of Open Access Journals (Sweden)

    Gabbani T

    2017-06-01

    Full Text Available Tommaso Gabbani,1 Simona Deiana,2 Vito Annese3 1Gastroenterology Unit, Morgagni-Pierantoni Hospital, AUSL Romagna, Forlì, 2Division of Gastroenterology, AOU Careggi University Hospital, Florence, Italy; 3Gastroenterology Department, Valiant Clinic, Dubai, UAE Abstract: The introduction of biological agents has revolutionized the management of many life-threatening and debilitating immune-mediated diseases. Because of the high cost of biological drugs and their patent expiration, the market has opened to biosimilar agents, copy versions of the originators, which can lead to reduced health care expenditure and increase treatment access worldwide. CT-P13 is the first biosimilar of infliximab (IFX and has been approved for the same indications as its originator drug. It obtained regulatory approval by the European Medicines Agency in September 2013 and by the US Food and Drug Administration in April 2016. The Phase I and Phase III clinical trials conducted in ankylosing spondylitis and rheumatoid arthritis have demonstrated pharmacokinetic and efficacy equivalence with comparable safety and immunogenicity to IFX. For these reasons, the use of CT-P13 has been extrapolated also to inflammatory bowel disease. There have been some initial concerns regarding the use of CT-P13 in inflammatory bowel disease patients, because of the lack of randomized controlled trials. However, emerging real-world data have further confirmed the comparability between CT-P13 and its reference product in terms of efficacy, safety, and immunogenicity, in patients naïve to the anti-tumor necrosis factor alpha agents and after switching from IFX, and will be summarized in this review. Keywords: CT-P13, infliximab, biosimilar, biologic therapy, Crohn’s disease, ulcerative colitis

  11. JUPITER PROJECT - MERGING INVERSE PROBLEM FORMULATION TECHNOLOGIES

    Science.gov (United States)

    The JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) project seeks to enhance and build on the technology and momentum behind two of the most popular sensitivity analysis, data assessment, calibration, and uncertainty analysis programs used in envi...

  12. Ceramic technology for Advanced Heat Engines Project

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.R.

    1991-07-01

    Significant accomplishments in fabricating ceramic components for advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. However, these programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and database and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. An assessment of needs was completed, and a five year project plan was developed with extensive input from private industry. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on the structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines. To facilitate the rapid transfer of this technology to US industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities. This project is managed by ORNL for the Office of Transportation Technologies, Office of Transportation Materials, and is closely coordinated with complementary ceramics tasks funded by other DOE offices, NASA, DOD, and industry.

  13. Geospatial Technologies: Real Projects in Real Classrooms

    Science.gov (United States)

    Kolvoord, Bob

    2008-01-01

    Geospatial technologies of geographic information systems, global positioning systems, and remote sensing are just a few of the projects that evoke an unexpected drive and devotion from high school students in Virginia. Their integration into different curricular areas lets students focus on understanding their community and the many issues that…

  14. NASA's Cryogenic Fluid Management Technology Project

    Science.gov (United States)

    Tramel, Terri L.; Motil, Susan M.

    2008-01-01

    The Cryogenic Fluid Management (CFM) Project's primary objective is to develop storage, transfer, and handling technologies for cryogens that will support the enabling of high performance cryogenic propulsion systems, lunar surface systems and economical ground operations. Such technologies can significantly reduce propellant launch mass and required on-orbit margins, reduce or even eliminate propellant tank fluid boil-off losses for long term missions, and simplify vehicle operations. This paper will present the status of the specific technologies that the CFM Project is developing. The two main areas of concentration are analysis models development and CFM hardware development. The project develops analysis tools and models based on thermodynamics, hydrodynamics, and existing flight/test data. These tools assist in the development of pressure/thermal control devices (such as the Thermodynamic Vent System (TVS), and Multi-layer insulation); with the ultimate goal being to develop a mature set of tools and models that can characterize the performance of the pressure/thermal control devices incorporated in the design of an entire CFM system with minimal cryogen loss. The project does hardware development and testing to verify our understanding of the physical principles involved, and to validate the performance of CFM components, subsystems and systems. This database provides information to anchor our analytical models. This paper describes some of the current activities of the NASA's Cryogenic Fluid Management Project.

  15. The New Mexico Technology Deployment Pilot Project: A technology reinvestment project. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The New Mexico Technology Deployment Project (NMTDP) has been in operation for slightly more than two years. As one of the original TRP projects, NMTDP had the charter to develop and validate a new model for technology extraction which emphasized focused technology collaboration, early industry involvement, and a strong dual use commercialization and productization emphasis. Taken in total, the first two years of the NMTDP have been exceptionally successful, surpassing the goals of the project. This report describes the accomplishments and evolution of the NMTDP to date and discusses the future potential of the project. Despite the end of federal funding, and a subsequent reduction in level of effort, the project partners are committed to continuation of the project.

  16. Biologically inspired technologies in NASA's morphing project

    Science.gov (United States)

    McGowan, Anna-Maria R.; Cox, David E.; Lazos, Barry S.; Waszak, Martin R.; Raney, David L.; Siochi, Emilie J.; Pao, S. Paul

    2003-07-01

    For centuries, biology has provided fertile ground for hypothesis, discovery, and inspiration. Time-tested methods used in nature are being used as a basis for several research studies conducted at the NASA Langley Research Center as a part of Morphing Project, which develops and assesses breakthrough vehicle technologies. These studies range from low drag airfoil design guided by marine and avian morphologies to soaring techniques inspired by birds and the study of small flexible wing vehicles. Biology often suggests unconventional yet effective approaches such as non-planar wings, dynamic soaring, exploiting aeroelastic effects, collaborative control, flapping, and fibrous active materials. These approaches and other novel technologies for future flight vehicles are being studied in NASA's Morphing Project. This paper will discuss recent findings in the aeronautics-based, biologically-inspired research in the project.

  17. Photovoltaic concentrator technology development project. Sixth project integration meeting

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-10-01

    Thirty-three abstracts and short papers are presented which describe the current status of research, development, and demonstration of concentrator solar cell technology. Solar concentrators discussed include the parabolic trough, linear focus Fresnel lens, point focus Fresnel lens, and the parabolic dish. Solar cells studied include silicon, GaAs, and AlGaAs. Research on multiple junction cells, combined photovoltaic/thermal collectors, back contact solar cells, and beam splitter modules is described. Concentrator solar cell demonstration programs are reported. Contractor status summaries are given for 33 US DOE concentrator solar cell contracts; a description of the project, project status, and key results to date is included. (WHK)

  18. Ceramic Technology Project database: September 1993 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1994-01-01

    Data presented in this report represent an intense effort to improve processing methods, testing methods, and general mechanical properties of candidate ceramics for use in advanced heat engines. Materials discussed include GN-10, GS-44, GTE PY6, NT-154, NT-164, sintered-reaction-bonded silicon nitrides, silicon nitride combined with rare-earth oxides, NT-230, Hexoloy SX-G1, Dow Corning`s {beta}-Si{sub 3}N{sub 4}, and a few whisker-reinforced ceramic composites. Information in this report was taken from the project`s semiannual and bimonthly progress reports and from final reports summarizing the results of individual studies. Test results are presented in tabular form and in graphs. All data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies but not to draw conclusions from those data.

  19. Supporting Project Work with Information Technology

    DEFF Research Database (Denmark)

    Heilesen, Simon

    2015-01-01

    Like so many other institutions, Roskilde University has had to adapt to the new realities brought about by the rapid developments in information and communication technology (ICT). On the whole, ICT tools have proven to be helpful in supporting and developing the work forms on which Roskilde...... University problem-oriented project work is based. However, in implementing and integrating the new technologies in academic practices, a number of challenges have had to be addressed. This chapter discusses four of these challenges. The first is to provide a physical and virtual framework for learning...

  20. National Security Technology Incubation Project Continuation Plan

    Energy Technology Data Exchange (ETDEWEB)

    None

    2008-09-30

    This document contains a project continuation plan for the National Security Technology Incubator (NSTI). The plan was developed as part of the National Security Preparedness Project (NSPP) funded by a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. This continuation plan describes the current status of NSTI (staffing and clients), long-term goals, strategies, and long-term financial solvency goals.The Arrowhead Center of New Mexico State University (NMSU) is the operator and manager of the NSTI. To realize the NSTI, Arrowhead Center must meet several performance objectives related to planning, development, execution, evaluation, and sustainability. This continuation plan is critical to the success of NSTI in its mission of incubating businesses with security technology products and services.

  1. Supporting Project Work with Information Technology

    DEFF Research Database (Denmark)

    Heilesen, Simon

    2015-01-01

    Like so many other institutions, Roskilde University has had to adapt to the new realities brought about by the rapid developments in information and communication technology (ICT). On the whole, ICT tools have proven to be helpful in supporting and developing the work forms on which Roskilde...... University problem-oriented project work is based. However, in implementing and integrating the new technologies in academic practices, a number of challenges have had to be addressed. This chapter discusses four of these challenges. The first is to provide a physical and virtual framework for learning...... activities. The second is to direct student use of ICT in terms of making systems available and teaching academic computing. The third challenge is to supervise and conduct project work online and in blended learning environments. Finally, one must find a way to exploit the potentials of ICT in problem...

  2. Advanced Turbine Technology Applications Project (ATTAP)

    Science.gov (United States)

    1993-01-01

    This report is the fifth in a series of Annual Technical Summary Reports for the Advanced Turbine Technology Applications Project (ATTAP), sponsored by the U.S. Department of Energy (DOE). The report was prepared by Garrett Auxiliary Power Division (GAPD), a unit of Allied-Signal Aerospace Company, a unit of Allied Signal, Inc. The report includes information provided by Garrett Ceramic Components, and the Norton Advanced Ceramics Company, (formerly Norton/TRW Ceramics), subcontractors to GAPD on the ATTAP. This report covers plans and progress on ceramics development for commercial automotive applications over the period 1 Jan. through 31 Dec. 1992. Project effort conducted under this contract is part of the DOE Gas Turbine Highway Vehicle System program. This program is directed to provide the U.S. automotive industry the high-risk, long-range technology necessary to produce gas turbine engines for automobiles with reduced fuel consumption, reduced environmental impact, and a decreased reliance on scarce materials and resources. The program is oriented toward developing the high-risk technology of ceramic structural component design and fabrication, such that industry can carry this technology forward to production in the 1990's. The ATTAP test bed engine, carried over from the previous AGT101 project, is being used for verification testing of the durability of next generation ceramic components, and their suitability for service at Reference Powertrain Design conditions. This document reports the technical effort conducted by GAPD and the ATTAP subcontractors during the fifth year of the project. Topics covered include ceramic processing definition and refinement, design improvements to the ATTAP test bed engine and test rigs, and the methodology development of ceramic impact and fracture mechanisms. Appendices include reports by ATTAP subcontractors in the development of silicon nitride materials and processes.

  3. Advanced Gas Turbine (AGT) technology development project

    Science.gov (United States)

    1987-01-01

    This report is the final in a series of Technical Summary Reports for the Advanced Gas Turbine (AGT) Technology Development Project, authorizrd under NASA Contract DEN3-167 and sponsored by the DOE. The project was administered by NASA-Lewis Research Center of Cleveland, Ohio. Plans and progress are summarized for the period October 1979 through June 1987. This program aims to provide the US automotive industry the high risk, long range technology necessary to produce gas turbine engines for automobiles that will reduce fuel consumption and reduce environmental impact. The intent is that this technology will reach the marketplace by the 1990s. The Garrett/Ford automotive AGT was designated AGT101. The AGT101 is a 74.5 kW (100 shp) engine, capable of speeds to 100,000 rpm, and operates at turbine inlet temperatures to 1370 C (2500 F) with a specific fuel consumption level of 0.18 kg/kW-hr (0.3 lbs/hp-hr) over most of the operating range. This final report summarizes the powertrain design, power section development and component/ceramic technology development.

  4. Workplace Factors That Shape Information Technology Project Success

    Science.gov (United States)

    Nguyen, Dan Schilling

    2013-01-01

    Information technology (IT) project success depends on having a project manager with effective decision making, leadership, and project management skills. Project success also depends on completing the project in a given budget, time, and scope. Despite these critical qualities of a successful project manager, little research has explored the…

  5. Large-scale filament formation inhibits the activity of CTP synthetase.

    Science.gov (United States)

    Barry, Rachael M; Bitbol, Anne-Florence; Lorestani, Alexander; Charles, Emeric J; Habrian, Chris H; Hansen, Jesse M; Li, Hsin-Jung; Baldwin, Enoch P; Wingreen, Ned S; Kollman, Justin M; Gitai, Zemer

    2014-07-16

    CTP Synthetase (CtpS) is a universally conserved and essential metabolic enzyme. While many enzymes form small oligomers, CtpS forms large-scale filamentous structures of unknown function in prokaryotes and eukaryotes. By simultaneously monitoring CtpS polymerization and enzymatic activity, we show that polymerization inhibits activity, and CtpS's product, CTP, induces assembly. To understand how assembly inhibits activity, we used electron microscopy to define the structure of CtpS polymers. This structure suggests that polymerization sterically hinders a conformational change necessary for CtpS activity. Structure-guided mutagenesis and mathematical modeling further indicate that coupling activity to polymerization promotes cooperative catalytic regulation. This previously uncharacterized regulatory mechanism is important for cellular function since a mutant that disrupts CtpS polymerization disrupts E. coli growth and metabolic regulation without reducing CTP levels. We propose that regulation by large-scale polymerization enables ultrasensitive control of enzymatic activity while storing an enzyme subpopulation in a conformationally restricted form that is readily activatable.

  6. Human CTP:phosphoethanolamine cytidylyltransferase: enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains.

    Science.gov (United States)

    Tian, Siqi; Ohtsuka, Jun; Wang, Shipeng; Nagata, Koji; Tanokura, Masaru; Ohta, Akinori; Horiuchi, Hiroyuki; Fukuda, Ryouichi

    2014-06-20

    CTP:phosphoethanolamine cytidylyltransferase (ECT) is a key enzyme in the CDP-ethanolamine branch of the Kennedy pathway, which is the primary pathway of phosphatidylethanolamine (PE) synthesis in mammalian cells. Here, the enzymatic properties of recombinant human ECT (hECT) were characterized. The catalytic reaction of hECT obeyed Michaelis-Menten kinetics with respect to both CTP and phosphoethanolamine. hECT is composed of two tandem cytidylyltransferase (CT) domains as ECTs of other organisms. The histidines, especially the first histidine, in the CTP-binding motif HxGH in the N-terminal CT domain were critical for its catalytic activity in vitro, while those in the C-terminal CT domain were not. Overexpression of the wild-type hECT and hECT mutants containing amino acid substitutions in the HxGH motif in the C-terminal CT domain suppressed the growth defect of the Saccharomyces cerevisiae mutant of ECT1 encoding ECT in the absence of a PE supply via the decarboxylation of phosphatidylserine, but overexpression of hECT mutants of the N-terminal CT domain did not. These results suggest that the N-terminal CT domain of hECT contributes to its catalytic reaction, but C-terminal CT domain does not. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Efficacy and safety of CT-P13 (biosimilar infliximab) in patients with rheumatoid arthritis: comparison between switching from reference infliximab to CT-P13 and continuing CT-P13 in the PLANETRA extension study

    Science.gov (United States)

    Yoo, Dae Hyun; Prodanovic, Nenad; Jaworski, Janusz; Miranda, Pedro; Ramiterre, Edgar; Lanzon, Allan; Baranauskaite, Asta; Wiland, Piotr; Abud-Mendoza, Carlos; Oparanov, Boycho; Smiyan, Svitlana; Kim, HoUng; Lee, Sang Joon; Kim, SuYeon; Park, Won

    2017-01-01

    Objectives To assess the efficacy and safety of switching from the infliximab reference product (RP; Remicade) to its biosimilar CT-P13 (Remsima, Inflectra) or continuing CT-P13 in patients with rheumatoid arthritis (RA) for an additional six infusions. Methods This open-label extension study recruited patients with RA who had completed the 54-week, randomised, parallel-group study comparing CT-P13 with RP (PLANETRA; NCT01217086). CT-P13 (3 mg/kg) was administered intravenously every 8 weeks from weeks 62 to 102. All patients received concomitant methotrexate. Endpoints included American College of Rheumatology 20% (ACR20) response, ACR50, ACR70, immunogenicity and safety. Data were analysed for patients who received CT-P13 for 102 weeks (maintenance group) and for those who received RP for 54 weeks and then switched to CT-P13 (switch group). Results Overall, 302 of 455 patients who completed the PLANETRA study enrolled into the extension. Of these, 158 had received CT-P13 (maintenance group) and 144 RP (switch group). Response rates at week 102 for maintenance versus switch groups, respectively, were 71.7% vs 71.8% for ACR20, 48.0% vs 51.4% for ACR50 and 24.3% vs 26.1% for ACR70. The proportion of patients with antidrug antibodies was comparable between groups (week 102: 40.3% vs 44.8%, respectively). Treatment-emergent adverse events occurred in similar proportions of patients in the two groups during the extension study (53.5% and 53.8%, respectively). Conclusions Comparable efficacy and tolerability were observed in patients who switched from RP to its biosimilar CT-P13 for an additional year and in those who had long-term CT-P13 treatment for 2 years. Trial registration number NCT01571219; Results. PMID:27130908

  8. Information technology project risk management in Peru

    OpenAIRE

    Del Carpio Gallegos, Javier; Universidad Nacional Mayor de San Marcos

    2014-01-01

    This article shows how some principles, uses, and practices of risk management are applied in information technology projects in Peru; in the last four years, in representative sectors like manufacturing, banking, information and communications, academics institutions, construction, government, consulting, services, and others. El presente artículo muestra algunos principios, usos y prácticas de cómo la gestión de riesgos de proyectos de tecnología se ha llevado a cabo en los últimos cuatr...

  9. Venture Leaders Prize for innovative technology projects

    CERN Multimedia

    2006-01-01

    In co-operation with the GEBERT RÜF FOUNDATION and the Ernest & Young Entrepreneur of the Year Award, venturelab will be presenting the Venture Leaders Prize. The Venture Leaders Prize, which is the new guise of the NETS (New Entrepreneurs in Technology and Science) Prize, will give twenty research entrepreneurs with projects to develop innovative technologies the opportunity to win the chance of participating in a programme to assist them in starting up their companies. The winners will go to spend 10 days in the Boston area (United States) where they will take part in a development programme for their project, which will include an entrepreneurship course, opportunities to meet start-up companies and financing experts, etc. This prize has already spawned many companies such as id Quantique, Selexis or ABMI which have contributed to the economic development of regions, particularly in French-speaking Switzerland. The competition is open to students and scientists from all fields, who would like to s...

  10. The Columbia River Protection Supplemental Technologies Quality Assurance Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fix, N. J.

    2008-03-12

    Pacific Northwest National Laboratory researchers are working on the Columbia River Protection Supplemental Technologies Project. This project is a U. S. Department of Energy, Office of Environmental Management-funded initiative designed to develop new methods, strategies, and technologies for characterizing, modeling, remediating, and monitoring soils and groundwater contaminated with metals, radionuclides, and chlorinated organics. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by the Technologies Project staff.

  11. Small Hydropower Research and Development Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Blackmore, Mo [Near Space Systems, Inc.

    2013-12-06

    The objective of this work was to investigate, develop, and validate the next generation of small hydroturbine generator designs that maximize the energy transfer from flowing water to electrical power generation. What resulted from this effort was the design of a new technology hydroturbine that Near Space Systems (NSS) has named the Star*Stream© Hydroturbine. Using a design that eliminates nearly all of the shortfalls of conventional hydroturbines, the Star*Stream© Hydroturbine employs a new mechanical-to-electrical energy transfer hydro design that operates without lubrication of any kind, and does not introduce foreign chemicals or particulate matter from oil or drive shaft seal degradation into the hydro ecology. In its unique configuration, the Star*Stream© Hydroturbine is nearly environmentally inert, without the negative aspects caused by interrupting the ecological continuity, i.e., disruptions to sedimentation, water quality, habitat changes, human displacement, fish migration, etc., - while it ensures dramatically reduced timeframes to project completion. While a remarkable reduction in LCOE resulting from application of the Star*Stream© Hydroturbine technology has been the core achievement of the this effort, there have been numerous technological breakthroughs from the development effort.

  12. CTP-5对食用菌种植基质的消毒种植试验%Planting Experiments of CTP-5 Disinfection to Mushroom Growing Substrate

    Institute of Scientific and Technical Information of China (English)

    张繁荣; 胡志辉; 周世力; 孙齐英; 许国权; 王兆霖

    2014-01-01

    Chooses two disinfectant,CTP-5 and carbendazim designs seven concentration gra-dient between 0~20 000 mg/L,after mushroom culture material handling,Inoculates mush-room strains and cultures. Researches the sterilizing effect of CTP-5 by observing the growth of mush-room mycelium and the growth of bacteria. The results show that CTP-5 and carbendazim both have obvious disinfection effect to mushroom culture material,the valid disinfection concentration of CTP-5 and carbendazim are respectively 10 000 mg/L and 8 000 mg/L. compared with high temper-ature sterilization group,the growth of mushroom mycelium is slower in medicone group. Compared with carbendazim group,the difference of disinfection effect and mycelium growth is not obvious in CTP-5 group. CTP-5 is a kind of new disinfectant which is innoxious and noresidue,can substitute for carbendazim to complementary disinfection and pollution prevention in mushroom culture materi-al.%试验选取CTP-5和多菌灵两种消毒剂,设计了0~20000 mg/L 7种浓度梯度组,对食用菌培养料进行处理后接种平菇菌种进行培养,通过观察食用菌菌丝的生长情况以及杂菌的生长情况,以研究CTP-5消毒灭菌效果。结果表明:CTP-5和多菌灵两种药剂处理培养料都具有明显的防污染效果,CTP-5和多菌灵的有效消毒灭菌浓度分别是10000 mg/L、8000 mg/L。但药物处理组与高温灭菌组对照比较,其菌丝生长较慢,CTP-5与多菌灵处理组比较,消毒效果和菌丝生长差异不明显。CTP-5是无毒\\无残留的新型消毒剂,可代替多菌灵在食用菌培养料中进行辅助消毒,防治污染。

  13. Clean Coal Technology Programs: Completed Projects (Volume 2)

    Energy Technology Data Exchange (ETDEWEB)

    Assistant Secretary for Fossil Energy

    2003-12-01

    Annual report on the Clean Coal Technology Demonstration Program (CCTDP), Power Plant Improvement Initiative (PPII), and Clean Coal Power Initiative (CCPI). The report addresses the roles of the programs, implementation, funding and costs, project descriptions, legislative history, program history, environmental aspects, and project contacts. The project descriptions describe the technology and provides a brief summary of the demonstration results.

  14. 30 CFR 402.11 - Technology-development project applications.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Technology-development project applications... RESEARCH PROGRAM AND THE WATER-RESOURCES TECHNOLOGY DEVELOPMENT PROGRAM Application, Evaluation, and Management Procedures § 402.11 Technology-development project applications. (a) Grant awards will be used...

  15. I-5/Gilman advanced technology bridge project

    Science.gov (United States)

    Lanza di Scalea, Francesco; Karbhari, Vistasp M.; Seible, Frieder

    2000-04-01

    The UCSD led I-5/Gilman Advanced Technology Bridge Project will design and construct a fully functional traffic bridge of advanced composite materials across Interstate 5 in La Jolla, California. Its objective is to demonstrate the use of advanced composite technologies developed by the aerospace industry in commercial applications to increase the life expectancy of new structures and for the rehabilitation of aging infrastructure components. The structure will be a 450 ft long, 60 ft wide cable-stayed bridge supported by a 150 ft A-frame pylon with two vehicular lanes, two bicycle lanes, pedestrian walkways and utility tunnels. The longitudinal girders and pylon will be carbon fiber shells filled with concrete. The transverse deck system will consist of hollow glass/carbon hybrid tubes and a polypropylene fiber reinforced concrete deck with an arch action. Selected cables will be composite. The bridge's structural behavior will be monitored to determine how advanced composite materials perform in civil infrastructure applications. The bridge will be instrumented to obtain performance and structural health data in real time and, where possible, in a remote fashion. The sensors applied to the bridge will include electrical resistance strain gages, fiberoptic Bragg gratings and accelerometers.

  16. Identification and Characterization of the Nuclear Isoform of Drosophila melanogaster CTP:Phosphocholine Cytidylyltransferase

    Science.gov (United States)

    CTP:phosphocholine cytidylyltransferase (CCT) catalyzes the conversion of phosphocholine and cytidine 5'-triphosphate (CTP) to CDP-choline for the eventual synthesis of phosphatidylcholine (PC). The enzyme is regulated by reversible association with cellular membranes, with the rate of catalysis in...

  17. Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

    DEFF Research Database (Denmark)

    Lauritsen, Iben; Willemoës, Martin; Jensen, Kaj Frank;

    2011-01-01

    CTP synthase catalyzes the last committed step in de novo pyrimidine-nucleotide biosynthesis. Active CTP synthase is a tetrameric enzyme composed of a dimer of dimers. The tetramer is favoured in the presence of the substrate nucleotides ATP and UTP; when saturated with nucleotide, the tetramer c...

  18. Nuclear Systems (NS): Technology Demonstration Unit (TDU) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Nuclear Systems Project demonstrates nuclear power technology readiness to support the goals of NASA’s Space Technology Mission Directorate. To this end,...

  19. Solid State Electrolyte for Li Battery Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration —  The fabrication technology developed in this project will aid GRC in advancing  Lithium Ion Batteries (LIB) technology by developing new electrode and SSE...

  20. Milliken Clean Coal Technology Demonstration Project. Project performance summary, Clean Coal Technology Demonstration Program

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-11-30

    The New York State Electric & Gas Corporation (NYSEG) demonstrated a combination of technologies at its Milliken Station in Lansing, New York, designed to: (1) achieve high sulfur dioxide (SO2) capture efficiency, (2) bring nitrogen oxide (NOx) emissions into compliance with Clean Air Act Amendments of 1990 (CAAA), (3) maintain high station efficiency, and (4) eliminate waste water discharge. This project is part of the U.S. Department of Energy's (DOE) Clean Coal Technology Demonstration Program (CCTDP) established to address energy and environmental concerns related to coal use. DOE sought cost-shared partnerships with industry through five nationally competed solicitations to accelerate commercialization of the most promising advance coal-based power generation and pollution control technologies. The CCTDP, valued at over five billion dollars, has significantly leveraged federal funding by forging effective partnerships founded on sound principles. For every federal dollar invested, CCTDP participants have invested two dollars. These participants include utilities, technology developers, state governments, and research organizations. The project presented here was one of nine selected in January 1991 from 33 proposals submitted in response to the program's fourth solicitation.

  1. Milliken Clean Coal Technology Demonstration Project. Project performance summary, Clean Coal Technology Demonstration Program

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-11-30

    The New York State Electric & Gas Corporation (NYSEG) demonstrated a combination of technologies at its Milliken Station in Lansing, New York, designed to: (1) achieve high sulfur dioxide (SO2) capture efficiency, (2) bring nitrogen oxide (NOx) emissions into compliance with Clean Air Act Amendments of 1990 (CAAA), (3) maintain high station efficiency, and (4) eliminate waste water discharge. This project is part of the U.S. Department of Energy's (DOE) Clean Coal Technology Demonstration Program (CCTDP) established to address energy and environmental concerns related to coal use. DOE sought cost-shared partnerships with industry through five nationally competed solicitations to accelerate commercialization of the most promising advance coal-based power generation and pollution control technologies. The CCTDP, valued at over five billion dollars, has significantly leveraged federal funding by forging effective partnerships founded on sound principles. For every federal dollar invested, CCTDP participants have invested two dollars. These participants include utilities, technology developers, state governments, and research organizations. The project presented here was one of nine selected in January 1991 from 33 proposals submitted in response to the program's fourth solicitation.

  2. Academic Training: The ITER project: technological challenges

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 31 May, 1, 2, 3, June from 11:00 to 12:00 on 31 May and 2, 3, June. From 10:00 to 12:00 on 1 June - Main Auditorium, bldg. 500 The ITER project: technological challenges J. LISTER / CRPP-EPFL, Lausanne, CH and P. BRUZZONE / CRPP-EPFL, Zürich, CH The first lecture reminds us of the ITER challenges, presents hard engineering problems, typically due to mechanical forces and thermal loads and identifies where the physics uncertainties play a significant role in the engineering requirements. The second lecture presents soft engineering problems of measuring the plasma parameters, feedback control of the plasma and handling the physics data flow and slow controls data flow from a large experiment like ITER. The last three lectures focus on superconductors for fusion. The third lecture reviews the design criteria and manufacturing methods for 6 milestone-conductors of large fusion devices (T-7, T-15, Tore Supra, LHD, W-7X, ITER). The evolution of the...

  3. Academic Training: The ITER project: technological challenges

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 31 May, 1, 2, 3, June from 11:00 to 12:00 on 31 May and 2, 3, June. From 10:00 to 12:00 on 1 June - Main Auditorium, bldg. 500 The ITER project: technological challenges J. LISTER / CRPP-EPFL, Lausanne and P. BRUZZONE / CRPP-EPFL, Zürich The first lecture reminds us of the ITER challenges, presents hard engineering problems, typically due to mechanical forces and thermal loads and identifies where the physics uncertainties play a significant role in the engineering requirements. The second lecture presents soft engineering problems of measuring the plasma parameters, feedback control of the plasma and handling the physics data flow and slow controls data flow from a large experiment like ITER. The last three lectures focus on superconductors for fusion. The third lecture reviews the design criteria and manufacturing methods for 6 milestone-conductors of large fusion devices (T-7, T-15, Tore Supra, LHD, W-7X, ITER). The evolution of the de...

  4. Science and Technology Roadmapping to Support Project Planning

    Energy Technology Data Exchange (ETDEWEB)

    Mc Carthy, Jeremiah Justin; Haley, Daniel Joseph; Dixon, Brent Wayne

    2001-07-01

    Disciplined science and technology roadmapping provides a framework to coordinate research and development activities with project objectives. This case-history paper describes initial project technology needs identification, assessment and R&D ranking activities supporting characterization of 781 waste tanks requiring a 'hazardous waste determination' or 'verification of empty' decision to meet an Idaho state Voluntary Consent Order.

  5. Manufacturing Methods and Technology Project Summary Reports.

    Science.gov (United States)

    1980-12-01

    as high speed machining. Except for the abrasive aluminum alloys like A356 which must be machined with carbide, either carbide or high speed steel...Shear Forging Processes for Missile 82 Primary Structure Project 376 3230 - Manufacturing Methods for High Speed Machining of 85 Aluminum Project 376 3231...Production Methods for Squeeze Castings 88 Projects 471 4312 and 472 4312 - Hard Face Coating to Aluminum Com- 91 ponents Project 576 6759

  6. Evaluation of Representative Smart Grid Investment Project Technologies: Demand Response

    Energy Technology Data Exchange (ETDEWEB)

    Fuller, Jason C.; Prakash Kumar, Nirupama; Bonebrake, Christopher A.

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of a limited number of demand response technologies and implementations deployed in the SGIG projects.

  7. Order of CT stroke protocol (CTA before or after CTP): impact on image quality

    Energy Technology Data Exchange (ETDEWEB)

    Dorn, Franziska [Technical University, Department of Radiology, Klinikum rechts der Isar, Munich (Germany); University Hospital of Cologne, Department of Radiology and Neuroradiology, Cologne (Germany); Institut fuer Radiologie, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich (Germany); Liebig, Thomas [University Hospital of Cologne, Department of Radiology and Neuroradiology, Cologne (Germany); Muenzel, Daniela; Meier, Reinhard; Rummeny, Ernst J.; Huber, Armin [Technical University, Department of Radiology, Klinikum rechts der Isar, Munich (Germany); Poppert, Holger [Technical University, Department of Neurology, Klinikum rechts der Isar, Munich (Germany)

    2012-02-15

    The purpose of this study was to determine the appropriate order of CT angiography and CT perfusion in a multimodal stroke CT protocol. Forty patients with clinical suspicion of an acute cerebral infarct underwent non-enhanced CT (NECT), CT angiography (CTA), and CT perfusion (CTP). Twenty examinations were performed with CTP before CTA (group 1) and 20 in reversed order (group 2). Mean densities were determined at baseline and peak enhancement of CTP, as well as on source images of CTA in defined brain regions. Contrast of extra-/intracranial arteries and veins was rated according to a 5-point scale (1 = excellent, 5 = poor). CT-perfusion maps were assessed by determining the mean transit time (MTT), cerebral blood flow (CBF), and blood volume (CBV) in identical regions. Mean densities between both groups were not significantly different for CTA and CTP at peak enhancement. At CTP baseline, mean densities between groups 1 and 2 were different for all points except for GM and WM. There was no significant difference between both groups for the mean delta (the difference between baseline and peak enhancement), as well as for mean MTT, CBV, and CBF. Subjective evaluation of the CTA quality revealed no difference between both protocols, except for the extracranial venous contrast, which was less severe in group 2. Reversal of CT stroke protocol had no significant influence on quantitative parameters of CTP. Subjective quality of extracranial venous contrast was rated to be superior when CTA was performed before CTP. (orig.)

  8. Assessing the Relationship between Ethical Project Management and Information Technology Project Success

    Science.gov (United States)

    Howell, Byron Winter

    2010-01-01

    The purpose of this quantitative study was to assess the relationship between ethical project management and information technology (IT) project success. The success of IT projects is important for organizational success, but the rate of IT projects is historically low, costing billions of dollars annually. Using four key ethical variables…

  9. An overview of the Communications Technology Satellite (CTS) project

    Science.gov (United States)

    Rapp, W.; Ogden, D.; Wright, D.

    1982-01-01

    The Communications Technology Satellite (CTS) project is reviewed. A technical description of the CTS spacecraft and its cognate hardware and operations is included. A historical treatise of the CTS project is provided. Also presented is an overview of the CTS experiments and demonstrations conducted during the course of the project.

  10. The Columbia River Protection Supplemental Technologies Quality Assurance Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fix, N. J.

    2007-01-10

    The U.S. Department of Energy (DOE) has conducted interim groundwater remedial activities on the Hanford Site since the mid-1990s for several groundwater contamination plumes. DOE established the Columbia River Protection Supplemental Technologies Project (Technologies Project) in 2006 to evaluate alternative treatment technologies. The objectives for the technology project are as follows: develop a 300 Area polyphosphate treatability test to immobilize uranium, design and test infiltration of a phosphate/apatite technology for Sr-90 at 100-N, perform carbon tetrachloride and chloroform attenuation parameter studies, perform vadose zone chromium characterization and geochemistry studies, perform in situ biostimulation of chromium studies for a reducing barrier at 100-D, and perform a treatability test for phytoremediation for Sr-90 at 100-N. This document provides the quality assurance guidelines that will be followed by the Technologies Project. This Quality Assurance Project Plan is based on the quality assurance requirements of DOE Order 414.1C, Quality Assurance, and 10 CFR 830, Subpart A--Quality Assurance Requirements as delineated in Pacific Northwest National Laboratory’s Standards-Based Management System. In addition, the technology project is subject to the Environmental Protection Agency (EPA) Requirements for Quality Assurance Project Plans (EPA/240/B-01/003, QA/R-5). The Hanford Analytical Services Quality Assurance Requirements Documents (HASQARD, DOE/RL-96-68) apply to portions of this project and to the subcontractors. HASQARD requirements are discussed within applicable sections of this plan.

  11. Propulsive Descent Technologies (PDT): Original Content Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future missions to Mars require landed mass that exceeds the capability of current entry, descent, and landing technology.  New technology and techniques are...

  12. Critical success factors in information technology projects

    Directory of Open Access Journals (Sweden)

    Ayesha

    2017-02-01

    Full Text Available The purpose of this study is to determine the critical success factors (CSF of IT projects in Pa-kistan. The identified factors cannot only be functional to exact type IT projects but also to all types of IT projects, their success directly affects the achievement of whole organization. The proposed study of this paper has determined 15 factors influencing the most on the success of IT projects through multiple regression analysis. The survey has disclosed that many CSFs were found related to IT projects but these 15 factors are also the backbone of IT projects. The re-search results obtained clearly indicated that the Leadership Qualities played a significant role in obtaining Top Management support in order to access to resources however, the Leadership Qualities did not play any role on the trained and capable Project Team Members. Besides, it is undoubtedly defined effective communication of the project was established to be influential on the conclusion and contributing factor towards the Success of IT projects in Pakistan. Top Man-agement Support as a whole was not found to play a key role in the IT Project Success.

  13. Project Management Plan for the INEL technology logic diagrams

    Energy Technology Data Exchange (ETDEWEB)

    Rudin, M.J.

    1992-10-01

    This Project Management Plan (PjMP) describes the elements of project planning and control that apply to activities outlined in Technical Task Plan (TTP) ID-121117, ``Technology Logic Diagrams For The INEL.`` The work on this project will be conducted by personnel in EG&G Idaho, Inc.`s Waste Technology Development Program. Technology logic diagrams represent a formal methodology to identify technology gaps or needs within Environmental Restoration/Waste Management Operations, which will focus on Office of Environmental Restoration and Waste Management (EM-50) research and development, demonstration, test, and evaluation efforts throughout the US Department of Energy complex. This PjMP describes the objectives, organization, roles and responsibilities, workscope and processes for implementing and managing the technology logic diagram for the Idaho National Engineering Laboratory project.

  14. Project Management Plan for the INEL technology logic diagrams

    Energy Technology Data Exchange (ETDEWEB)

    Rudin, M.J.

    1992-10-01

    This Project Management Plan (PjMP) describes the elements of project planning and control that apply to activities outlined in Technical Task Plan (TTP) ID-121117, Technology Logic Diagrams For The INEL.'' The work on this project will be conducted by personnel in EG G Idaho, Inc.'s Waste Technology Development Program. Technology logic diagrams represent a formal methodology to identify technology gaps or needs within Environmental Restoration/Waste Management Operations, which will focus on Office of Environmental Restoration and Waste Management (EM-50) research and development, demonstration, test, and evaluation efforts throughout the US Department of Energy complex. This PjMP describes the objectives, organization, roles and responsibilities, workscope and processes for implementing and managing the technology logic diagram for the Idaho National Engineering Laboratory project.

  15. BMDO: New Mexico Technology Transfer Demonstration Project. Interim final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    The BMDO-New Mexico Technology Transfer Demonstration Project(BMDO-NM) was a collaborative effort among the national laboratories to identify and evaluate the commercial potential of selected SDI-funded technologies. The project was funded by BMDO (formerly known as the Strategic Defense Initiative Office or SDIO), the Technology Enterprise Division (NM-TED) of the NM Economic Development Division, and the three National Laboratories. The project was managed and supervised by SAGE Management Partners of Albuquerque, and project funding was administered through the University of New Mexico. The BMDO-NM Demonstration Project focused on the development of a process to assist technology developers in the evaluation of selected BMDO technology programs so that commercialization decisions can be made in an accelerated manner. The project brought together BMDO, the NM-TED, the University of New Mexico, and three New Mexico Federal laboratories -- Los Alamos (DOE), Phillips (DOD) and Sandia (DOE). Each national laboratory actively participated throughout the project through its technology transfer offices. New Mexico was selected as the site for the Demonstration Program because of its three national and federal research laboratories engaged in BMDO programs, and the existing relationship among state govemment, the labs, universities and local economic development and business assistance organizations. Subsequent Commercialization and Implementation phases for the selected technologies from LANL and SNL were completed by SAGE and the Project Team. Funding for those phases was provided by the individual labs as well as BMDO and NM-TED in kind services. NM-TED played a proactive role in this New Mexico partnership. Its mandate is to promote technology-based economic development, with a commitment to facilitate the use of technology by industry and business statewide. TED assumed the role of program manager and executing agent for BMDO in this demonstration project.

  16. Current Renewable Energy Technologies and Future Projections

    Energy Technology Data Exchange (ETDEWEB)

    Allison, Stephen W [ORNL; Lapsa, Melissa Voss [ORNL; Ward, Christina D [ORNL; Smith, Barton [ORNL; Grubb, Kimberly R [ORNL; Lee, Russell [ORNL

    2007-05-01

    The generally acknowledged sources of renewable energy are wind, geothermal, biomass, solar, hydropower, and hydrogen. Renewable energy technologies are crucial to the production and utilization of energy from these regenerative and virtually inexhaustible sources. Furthermore, renewable energy technologies provide benefits beyond the establishment of sustainable energy resources. For example, these technologies produce negligible amounts of greenhouse gases and other pollutants in providing energy, and they exploit domestically available energy sources, thereby reducing our dependence on both the importation of fossil fuels and the use of nuclear fuels. The market price of renewable energy technologies does not reflect the economic value of these added benefits.

  17. In-Space Propulsion (346620) Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Technologies include, but are not limited to, electric and advanced chemical propulsion, propellantless propulsion such as aerocapture and solar sails, sample return...

  18. Cryogenic MEMS Technology for Sensing Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The development of cryogenic microwave components, such as focal plane polarization modulators, first requires an RF MEMS switching technology that operates...

  19. A Survey of Technologies Supporting Virtual Project Based Learning

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Lone

    2002-01-01

    This paper describes a survey of technologies and to what extent they support virtual project based learning. The paper argues that a survey of learning technologies should be related to concrete learning tasks and processes. Problem oriented project pedagogy (POPP) is discussed, and a framework...... for evaluation is proposed where negotiation of meaning, coordination and resource management are identified as the key concepts in virtual project based learning. Three e-learning systems are selected for the survey, Virtual-U, Lotus Learningspace and Lotus Quickplace, as each system offers different strategies...... for e-learning. The paper concludes that virtual project based learning may benefit from facilities of all these systems....

  20. CNPC Appoints Chief Experts for Important Technological Projects

    Institute of Scientific and Technical Information of China (English)

    Zhao Jianzhong

    2006-01-01

    @@ On June 27th, China National Petroleum Corporation (CNPC) held a public recruitment to appoint chief experts in Beijing for its important technological projects, which is the first time for CNPC to appoint chief managers by the means of competitive recruitment. This recruitment covers four projects, such as drilling, logging, geophysical survey and ground engineering with 15 projects. Of those,there are 8 drilling projects, which make up 50 percent of all the important technological projects for public recruitment. CNPC expects to further boost the chief expert responsibility system and promote the research and development (R&D) of technological project on the basis of the public recruitment. The company completes the recruitment following the procedure of making announcement, conducting competitive recruitment and giving publicity. On July 25th, the appointment ceremony was held by CNPC and 15 experts were awarded the certificates. CNPC is entering a new stage for the implementation of the technology and talent strategy for the 11th Five-Year Plan. What's more, a new management mode is taking shape for the technological project and for the construction of technological personnel pool.

  1. Slot Coupled Patch Array Antenna Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed project is an antenna array whose beam is controlled digitally. The Phase 1 effort will assess the method needed to achieve the gain, bandwidth, and...

  2. Success in large high-technology projects: What really works?

    Science.gov (United States)

    Crosby, P.

    2014-08-01

    Despite a plethora of tools, technologies and management systems, successful execution of big science and engineering projects remains problematic. The sheer scale of globally funded projects such as the Large Hadron Collider and the Square Kilometre Array telescope means that lack of project success can impact both on national budgets, and collaborative reputations. In this paper, I explore data from contemporary literature alongside field research from several current high-technology projects in Europe and Australia, and reveal common `pressure points' that are shown to be key influencers of project control and success. I discuss the how mega-science projects sit between being merely complicated, and chaotic, and explain the importance of understanding multiple dimensions of project complexity. Project manager/leader traits are briefly discussed, including capability to govern and control such enterprises. Project structures are examined, including the challenge of collaborations. I show that early attention to building project resilience, curbing optimism, and risk alertness can help prepare large high-tech projects against threats, and why project managers need to understand aspects of `the silent power of time'. Mission assurance is advanced as a critical success function, alongside the deployment of task forces and new combinations of contingency plans. I argue for increased project control through industrial-style project reviews, and show how post-project reviews are an under-used, yet invaluable avenue of personal and organisational improvement. Lastly, I discuss the avoidance of project amnesia through effective capture of project knowledge, and transfer of lessons-learned to subsequent programs and projects.

  3. Manufacturing Methods and Technology Project Summary Reports

    Science.gov (United States)

    1982-06-01

    variation. The goal of this FY78 project was to solve these problems, develop pilot line production of 200 ferrites , and test them. SWITCHING ...WIRES FERRITE HIGH &. DIELECTRIC ^ mm i ii ’&Z2ZL f M Figure 1 - Non-Reciprocal Latching Phase Shifter - Side Loaded Geometry 39 i SUMMARY...Control Manufacturing Modernization Plan 18 ELECTRONICS Project 273 9638 - Integrated Hybrid Transistor Switch for Solid 21 State Converter

  4. Picosats for Autonomous Rendezvous and Docking Technology Demonstration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Over the next decade, a host of new technologies and capabilities will be needed by NASA to support Project Constellation. For risk reduction considerations, it is...

  5. Fabrication Technology for X-Ray Optics and Mandrels Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has a cross-project need for large format aspheric x-ray optics, which, demonstrate exceptionally low periodic surface errors. Available technologies to both...

  6. The Role of the Project Management Office on Information Technology Project Success

    Science.gov (United States)

    Stewart, Jacob S.

    2010-01-01

    The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. Assessing critical success factors is another…

  7. The Role of the Project Management Office on Information Technology Project Success

    Science.gov (United States)

    Stewart, Jacob S.

    2010-01-01

    The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. Assessing critical success factors is another…

  8. Human Robotic Systems (HRS): Rover Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In FY15, the HRS Rover Technologies will begin design of a prototype rover designed for the lunar surface, begin development of resource efficient navigation...

  9. Advanced Manufacturing Technologies (AMT): Manufacturing Initiative Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA supports the Advanced Manufacturing National Program Office (AMNPO). Hosted by the National Institute of Standards and Technology (NIST) the AMNPO is...

  10. Braided Composite Technologies for Rotorcraft Structures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed program will focus on the development of a new generation of advanced technology for rotorcraft transmission systems. This program will evaluate the...

  11. Braided Composite Technologies for Rotorcraft Structures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Phase 2 effort will be used to advance the material and design technologies that were explored in the Phase 1 study of hybrid gears. In this hybrid approach, the...

  12. Extreme Environment Hybrid Gearbox Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Nearly all mechanism applications require some form of gearbox. Wet lubricated gearbox technologies are limited to the relatively narrow temperature ranges of their...

  13. Advanced Manufacturing Technologies (AMT): Advanced Near Net Shape Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop and mature manufacturing technology to enable fabrication of single-piece integrally-stiffened launch vehicle structures to replace expensive, heavy, and...

  14. Numerical modeling in photonic crystals integrated technology: the COPERNICUS Project

    DEFF Research Database (Denmark)

    Malaguti, Stefania; Armaroli, Andrea; Bellanca, Gaetano

    2011-01-01

    Photonic crystals will play a fundamental role in the future of optical communications. The relevance of the numerical modeling for the success of this technology is assessed by using some examples concerning the experience of the COPERNICUS Project.......Photonic crystals will play a fundamental role in the future of optical communications. The relevance of the numerical modeling for the success of this technology is assessed by using some examples concerning the experience of the COPERNICUS Project....

  15. Essays on Technology Adoption and Provision Efficiency in Development Projects

    OpenAIRE

    2016-01-01

    In many development projects, technologies with potential to improve welfare are under adopted and under-utilized once adopted. One possible cause for this inefficiency is ignoring fit risk (the risk the technology may not meet the needs of the potential adopter). This dissertation attempts to introduce fit risk in the development context and develops a framework to analyze resource misallocation when fit risk is not addressed by project donors and managers. We examine strategies to reduce fi...

  16. Numerical modeling in photonic crystals integrated technology: the COPERNICUS Project

    DEFF Research Database (Denmark)

    Malaguti, Stefania; Armaroli, Andrea; Bellanca, Gaetano

    2011-01-01

    Photonic crystals will play a fundamental role in the future of optical communications. The relevance of the numerical modeling for the success of this technology is assessed by using some examples concerning the experience of the COPERNICUS Project.......Photonic crystals will play a fundamental role in the future of optical communications. The relevance of the numerical modeling for the success of this technology is assessed by using some examples concerning the experience of the COPERNICUS Project....

  17. Leadership Styles: Perceptions in Information Technology Project Teams

    Science.gov (United States)

    Fune, Roy P.

    2013-01-01

    The purpose of this study was to uncover Information Technology (IT) Project Managers' and IT Professionals' perceptions of effective leadership styles as they apply to project success. There have been prior studies dealing with the differences in perceptions between IT Functional Manager's leadership self-perception versus staff perceptions of…

  18. Project-Based Learning in Electronic Technology: A Case Study

    Science.gov (United States)

    Li, Li

    2015-01-01

    A case study of project-based learning (PBL) implemented in Tianjin University of Technology and Education is presented. This multidiscipline project is innovated to meet the novel requirements of industry while keeping its traditional effectiveness in driving students to apply knowledge to practice and problem-solving. The implementation of PBL…

  19. Leadership Styles: Perceptions in Information Technology Project Teams

    Science.gov (United States)

    Fune, Roy P.

    2013-01-01

    The purpose of this study was to uncover Information Technology (IT) Project Managers' and IT Professionals' perceptions of effective leadership styles as they apply to project success. There have been prior studies dealing with the differences in perceptions between IT Functional Manager's leadership self-perception versus staff perceptions of…

  20. Project-Based Learning in Electronic Technology: A Case Study

    Science.gov (United States)

    Li, Li

    2015-01-01

    A case study of project-based learning (PBL) implemented in Tianjin University of Technology and Education is presented. This multidiscipline project is innovated to meet the novel requirements of industry while keeping its traditional effectiveness in driving students to apply knowledge to practice and problem-solving. The implementation of PBL…

  1. Nuestra Tierra: A University/Public School Technology Integration Project.

    Science.gov (United States)

    Wiburg, Karin M.; Montoya, Nidelia; Sandin, John

    1999-01-01

    Describes a university/public school project to integrate technology with teaching and learning in a Southwest border school district. Discusses how the project was collaboratively designed, implemented, and evaluated by university faculty and school teachers and administrators. Findings demonstrated the potential of university researchers working…

  2. Leadership Styles: Perceptions in Information Technology Project Teams

    Science.gov (United States)

    Fune, Roy P.

    2013-01-01

    The purpose of this study was to uncover Information Technology (IT) Project Managers' and IT Professionals' perceptions of effective leadership styles as they apply to project success. There have been prior studies dealing with the differences in perceptions between IT Functional Manager's leadership self-perception versus staff…

  3. Manufacturing Methods and Technology Project Summary Reports

    Science.gov (United States)

    1982-12-01

    MORE INFORMATION 1 Additional information can be obtained from the project officer, Mr. Nathaniel Scott, ARRADCOM, AV 880-6945 or Commercial (201...QAM6, Mr. S. R. Caswell Cdr, Hawthorne AAP, Attn: SARHW-CO Cdr, Holston AAP, Attn: SARHO-CO Cdr, Indiana AAP, Attn: SARIN-CO AII-3 DRXIB-MT

  4. Underwater communication. FOA-STU project 4: Maritime technology

    Science.gov (United States)

    Goetherstroem, L.; Kleman, B.; Lindquist, R.; Pentelius, T.

    1980-04-01

    Technological forecasts for underwater communication by acoustical, optical, or radio techniques are summarized. Results on transmission by the various means were evaluated under different hypotheses for the aqueous milieu. Technological possibilities, the need for underwater communications in assorted applications, and a practical assessment of the potential for realization are considered. Conclusions lead to a proposal for a series of development projects.

  5. Fuel Cell Technology Status Analysis Project: Partnership Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    2017-03-13

    Fact sheet describing the National Renewable Energy Laboratory's (NREL's) Fuel Cell Technology Status Analysis Project. NREL is seeking fuel cell industry partners from the United States and abroad to participate in an objective and credible analysis of commercially available fuel cell products to benchmark the current state of the technology and support industry growth.

  6. NASA Composite Cryotank Technology Project Game Changing Program

    Science.gov (United States)

    Fikes, John

    2015-01-01

    The fundamental goal of this project was to provide new and innovative cryotank technologies that enable human space exploration to destinations beyond low earth orbit such as the moon, near-earth asteroids, and Mars. The goal ... to mature technologies in preparation for potential system level flight demonstrations through significant ground-based testing and/or laboratory experimentation

  7. A Partnership Project: Integrating Computer Technology and Orff-Schulwerk.

    Science.gov (United States)

    Woody, Robert H.; Fredrickson, Julie M.

    2000-01-01

    Describes an alternative approach for general music educators wanting to study new instructional strategies in which a classroom teacher and university educator collaborated to explore the integration of computer technology with Orff-Schulwerk in second- and third-grade music classes. Discusses the project and two of its technology-assisted…

  8. Technology Transfer and Outreach for SNL/Rochester ALPHA Project.

    Energy Technology Data Exchange (ETDEWEB)

    Sinars, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-01-01

    This report describes the next stage goals and resource needs for the joint Sandia and University of Rochester ARPA-E project. A key portion of this project is Technology Transfer and Outreach, with the goal being to help ensure that this project develops a credible method or tool that the magneto-inertial fusion (MIF) research community can use to broaden the advocacy base, to pursue a viable path to commercial fusion energy, and to develop other commercial opportunities for the associated technology. This report describes an analysis of next stage goals and resource needs as requested by Milestone 5.1.1.

  9. Electrical Impedance Tomography Technology (EITT) Project

    Science.gov (United States)

    Oliva-Buisson, Yvette J.

    2014-01-01

    Development of a portable, lightweight device providing two-dimensional tomographic imaging of the human body using impedance mapping. This technology can be developed to evaluate health risks and provide appropriate medical care on the ISS, during space travel and on the ground.

  10. Force Project Technology Presentation to the NRCC

    Science.gov (United States)

    2014-02-04

    cycle engineering for: – Fuel Handling & Quality Surveillance Equipment – Water Purification , Handling, & Quality Equipment – Combat Engineer...Material Handling Equipment – Military Bridging – Fuels and Lubricants – Army Petroleum Laboratory • Respond to Maneuver Support Center of...Systems & Latrines  A gray water reuse technology (TRL 6) that treats water from current CSS equipment to include Water Purification Systems & Shower

  11. Ceramic Technology Project semiannual progress report, October 1992--March 1993

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.R.

    1993-09-01

    This project was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. Although progress has been made in developing reliable structural ceramics, further work is needed to reduce cost. The work described in this report is organized according to the following work breakdown structure project elements: Materials and processing (monolithics [Si nitride, carbide], ceramic composites, thermal and wear coatings, joining, cost effective ceramic machining), materials design methodology (contact interfaces, new concepts), data base and life prediction (structural qualification, time-dependent behavior, environmental effects, fracture mechanics, nondestructive evaluation development), and technology transfer.

  12. Minimal Technologies Application Project: Planning and installation

    Energy Technology Data Exchange (ETDEWEB)

    Zellmer, S.D.; Hinchman, R.R.; Severinghaus, W.D.; Johnson, D.O.; Brent, J.J.

    1989-03-01

    Intensive and continuous tactical training during the last 35 years at the Hohenfels Training Area in West Germany has caused the loss of vegetative ground cover and has accelerated soil erosion rates, resulting in extensive environmental damage, safety hazards, and unrealistic training habitats. The objectives of this project are to develop and evaluate revegetation procedures for establishing adequate vegetative cover to control erosion at minimal costs and disruption to training activities. This project involved the development and installation of 12 revegetation procedures that combined four seedbed preparation methods and seeding options with three site-closure periods. In March 1987, the four seedbed preparation/seeding options and closure periods were selected, a study site design and location chosen, and specifications for the revegetation procedures developed. A German rehabilitation contractor attempted the specified seedbed preparation and seeding on the 13.5-ha site in June, but abnormally high rainfall, usually wet site conditions, and lack of adequate equipment prevented the contractor from completing six of the 12 planned procedures. Planning and execution of the project has nonetheless provided valuable information on the importance and use of soil analytical results, seed availability and cost data, contractor equipment requirements, and time required for planning future revegetation efforts. Continued monitoring of vegetative ground cover at the site for the next two years, combined with cost information, will provide necessary data to determine which of the six revegetation procedures is the most effective. These data will be used in planning future rehabilitation efforts on tactical training areas.

  13. Korea-China Optical Technology Research Centre Project

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Cheol Jung; Rhee, Y. J.; Jung, D. Y. and others

    2004-06-15

    The main objectives of this project are to establish the international collaboration basis of optical technologies between Korea and China. The combination of the Chinese advanced fundamental technologies with the Korean industrialization and commercialization infrastructures is realized, by ways of exchanging scientists and informations, holding joint seminars, cooperative utilization of research resources. On the ground of this establishment, the optical technologies of Korea are supposed to be leveled up to those of the world-most advanced. At the same time, for the improvement of mutual benefit and financial profit of both countries, providing technical advice and suggestions to the optical industries in the two countries is an another goal of this project. The state-of-the-arts of the Chinese technologies such as aerospace engineering, military defence technology, medical technology, laser fusion research, and so on, are known to be far above those of Korean and up to one of the most advanced in the world. Thus it is thought to be necessary that the acquisition of these technologies, implementation of joint research projects for technology development as well as the balanced opportunities for commercial product/sales and cooperation should be actively pursued in order to enhance the levels of Korean technologies in these fields.

  14. SUCCESS CONCEPT ANALYSIS APPLIED TO THE INFORMATION TECHNOLOGY PROJECT MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Cassio C. Montenegro Duarte

    2012-05-01

    Full Text Available This study evaluates the concept of success in project management that is applicable to the IT universe, from the classical theory associated with the techniques of project management. Therefore, it applies the theoretical analysis associated to the context of information technology in enterprises as well as the classic literature of traditional project management, focusing on its application in business information technology. From the literature developed in the first part of the study, four propositions were prepared for study which formed the basis for the development of the field research with three large companies that develop projects of Information Technology. The methodology used in the study predicted the development of the multiple case study. Empirical evidence suggests that the concept of success found in the classical literature in project management adjusts to the environment management of IT projects. Showed that it is possible to create the model of standard IT projects in order to replicate it in future derivatives projects, which depends on the learning acquired at the end of a long and continuous process and sponsorship of senior management, which ultimately results in its merger into the company culture.

  15. Keynote presentation: Project Management, Technology and Evolving Work Processes

    DEFF Research Database (Denmark)

    Kampf, Constance Elizabeth

    Bridging the classroom and workplace is a challenge in the Project Management classroom because students rarely have the opportunity or the experience needed to head up large projects. So how can instructors present the opportunity to develop skills and gain experience needed to understand project...... management in a classroom setting? To begin to answer this question, the presentation describes three key strategies used in a Project Management course developed from a communications perspective in the International Bachelor Program in Marketing and Management Communication, Business & Social Sciences...... Management regardless of the technology used to support it....

  16. Didactics, Technology, and Organisation of Project Based Distance Education

    DEFF Research Database (Denmark)

    Knudsen, Morten Haack; Borch, Ole M.; Helbo, Jan

    2005-01-01

    The didactics, technology, and organization of an ICT supported distance engineering Master education are described. A systematic monitoring and evaluation of the basis year has given useful experience, subsequently used for adjustments and improvements. A successful on-campus project organized...... learning method applied at Aalborg University has been transferred to the off-campus situation. Experience show that didactic adjustments are required, in particular for obtaining an optimal balance between course and project work. Project collaboration in groups requires communication, synchronous as well......, was constructed. This system, called Uniflex, handles project work, courses, and exchange of information between the administrative coordinator, students and teachers....

  17. Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase

    DEFF Research Database (Denmark)

    Wadskov-Hansen, Steen Lyders Lerche; Willemoës, M.; Martinussen, Jan

    2001-01-01

    The pyrG gene of Lactococcus lactis subsp. cremoris, encoding CTP synthase, has been cloned and sequenced. It is flanked upstream by an open reading frame showing homology to several aminotransferases and downstream by an open reading frame of unknown function. L. lactis strains harboring disrupted...... of a functional cdd gene encoding cytidine deaminase. A characterization of the enzyme revealed similar properties as found for CTP synthases from other organisms. However, unlike the majority of CTP synthases the lactococcal enzyme can convert dUTP to dCTP, although a half saturation concentration of 0.6 m...

  18. NASA Fixed Wing Project: Green Technologies for Future Aircraft Generation

    Science.gov (United States)

    DelRosario, Ruben

    2014-01-01

    The NASA Fundamental Aeronautics Fixed Wing (FW) Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advances in multidisciplinary technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the FW Project vision of revolutionary systems and technologies needed to achieve the challenging goals of aviation. Specifically, the primary focus of the FW Project is on the N+3 generation that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe.

  19. Disruption of Information Technology Projects: The Reactive Decoupling of Project Management Methodologies

    Science.gov (United States)

    Schmitz, Kurt W.

    2013-01-01

    Information Technology projects have migrated toward two dominant Project Management (PM) methodologies. Plan-driven practices provide organizational control through highly structured plans, schedules, and specifications that facilitate oversight by hierarchical bureaucracies. In contrast, agile practices emphasize empowered teams using flexible…

  20. Disruption of Information Technology Projects: The Reactive Decoupling of Project Management Methodologies

    Science.gov (United States)

    Schmitz, Kurt W.

    2013-01-01

    Information Technology projects have migrated toward two dominant Project Management (PM) methodologies. Plan-driven practices provide organizational control through highly structured plans, schedules, and specifications that facilitate oversight by hierarchical bureaucracies. In contrast, agile practices emphasize empowered teams using flexible…

  1. Influence of Strategic Management Project Portfolio in Technological Development

    OpenAIRE

    Bitencourt, Lorene Carvalho; Garcez, Marcos Paixão

    2013-01-01

    This text aims to present a case of a multinational company that acts in construction and furniture markets. For three years ago the company had implemented an area of portfolio project management with objective of using strategic criteria to select project that contributes with technologic development of the company. The methodology of this study was grounded in Castro and Carvalho theoretical reference for analyze the implementation process and the tools used by portfolio management. The re...

  2. REGULATORY FUNDAMENTALS FOR IMPLEMENTATION OF INFORMATION TECHNOLOGY PROJECTS IN INDUSTRY

    Directory of Open Access Journals (Sweden)

    L. V. Gubich

    2016-01-01

    Full Text Available The article provides an overview of the existing regulatory basis for the development of IIST. The features of IT projects management and a brief description of methodological recommendations on implementation of IT projects of the State scientific and technical Program «Electronic enterprise resource planning (CALS-ERP-technology» for 2011–2015 are considered.

  3. Ceramic Technology Project. Semiannual progress report, April 1991--September 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The Ceramic Technology Project was developed by the USDOE Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS`s Materials Development Program, was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. Significant accomplishments in fabricating ceramic components for the USDOE and NASA advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. These programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and data base and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. A five-year project plan was developed with extensive input from private industry. In July 1990 the original plan was updated through the estimated completion of development in 1993. The objective is to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on the structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines. To facilitate the rapid transfer of this technology to US industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities.

  4. Collaborative Project-Based Learning: An Integrative Science and Technological Education Project

    Science.gov (United States)

    Baser, Derya; Ozden, M. Yasar; Karaarslan, Hasan

    2017-01-01

    Background: Blending collaborative learning and project-based learning (PBL) based on Wolff (2003) design categories, students interacted in a learning environment where they developed their technology integration practices as well as their technological and collaborative skills. Purpose: The study aims to understand how seventh grade students…

  5. Application of Technology in Project-Based Distance Learning

    Directory of Open Access Journals (Sweden)

    Ali Mehrabian

    2008-06-01

    Full Text Available Present technology and the accessibility of internet have made distance learning easier, more efficient, and more convenient for students. This technology allows instructors and students to communicate asynchronously, at times and locations of their own choosing, by exchanging printed or electronic information. The use of project-based approach is being recognized in the literature as a potential component of courses in the faculties of engineering, science, and technology. Instructors may have to restructure their course differently to accommodate and facilitate the effectiveness of distance learning. A project-based engineering course, traditionally taught in a classroom settings using live mode at the College of Engineering and Computer Sciences at the University of Central Florida (UCF has been transformed to a distance course taught using distance modes. In this case, pedagogical transitions and adjustments are required, in particular for obtaining an optimal balance between the course material and the project work. Project collaboration in groups requires communication, which is possible with extensive utilization of new information and communication technology, such as virtual meetings. This paper discusses the course transition from live to distance modes and touches on some issues as they relate to the effectiveness of this methodology and the lessons learned from its application within different context. More specifically, this discussion includes the benefit of implementing project-based work in the domain of the distance learning courses.

  6. Didactics, Technology, and Organisation of Project Based Distance Education

    DEFF Research Database (Denmark)

    Knudsen, Morten Haack; Borch, Ole M.; Helbo, Jan

    2005-01-01

    learning method applied at Aalborg University has been transferred to the off-campus situation. Experience show that didactic adjustments are required, in particular for obtaining an optimal balance between course and project work. Project collaboration in groups requires communication, synchronous as well...... as asynchronous, which is possible with extensive utilization of new information and communication technology. Virtual meetings are conducted with text, sound and video based communication. Also the organization requires technology. A new learning management system, specifically designed to the didactic form...

  7. Job Diagnostic Survey: A Team Project Information Technology Perspective

    Directory of Open Access Journals (Sweden)

    Renato Telles

    2016-10-01

    Full Text Available This work aims to understand the effects of management styles on the work motivation of a team project in the telecommunications information technology context. To understand this complex behavior, we use the Job Diagnostic Survey methodology. In this critical analysis, we identify the main factors for failure in the field of telecommunications. The managers need to implement a methodology and define processes and formal procedures that need to be applied during the development of projects to mitigate the risk of failure and maintain control over it. One of the main findings in this research is associated with challenges and motivation by the Information Technology (IT professionals.

  8. Advanced Turbine Technology Applications Project (ATTAP) and Hybrid Vehicle Turbine Engine Technology Support project (HVTE-TS): Final summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    This final technical report was prepared by Rolls-Royce Allison summarizing the multiyear activities of the Advanced Turbine Technology Applications Project (ATTAP) and the Hybrid Vehicle Turbine Engine Technology Support (HVTE-TS) project. The ATTAP program was initiated in October 1987 and continued through 1993 under sponsorship of the US Department of Energy (DOE), Energy Conservation and Renewable Energy, Office of Transportation Technologies, Propulsion Systems, Advanced Propulsion Division. ATTAP was intended to advance the technological readiness of the automotive ceramic gas turbine engine. The target application was the prime power unit coupled to conventional transmissions and powertrains. During the early 1990s, hybrid electric powered automotive propulsion systems became the focus of development and demonstration efforts by the US auto industry and the Department of energy. Thus in 1994, the original ATTAP technology focus was redirected to meet the needs of advanced gas turbine electric generator sets. As a result, the program was restructured to provide the required hybrid vehicle turbine engine technology support and the project renamed HVTE-TS. The overall objective of the combined ATTAP and HVTE-TS projects was to develop and demonstrate structural ceramic components that have the potential for competitive automotive engine life cycle cost and for operating 3,500 hr in an advanced high temperature turbine engine environment. This report describes materials characterization and ceramic component development, ceramic components, hot gasifier rig testing, test-bed engine testing, combustion development, insulation development, and regenerator system development. 130 figs., 12 tabs.

  9. Crystal structure of Sulfolobus acidocaldarius aspartate carbamoyltransferase in complex with its allosteric activator CTP.

    Science.gov (United States)

    De Vos, Dirk; Xu, Ying; Aerts, Tony; Van Petegem, Filip; Van Beeumen, Jozef J

    2008-07-18

    Aspartate carbamoyltransferase (ATCase) is a paradigm for allosteric regulation of enzyme activity. B-class ATCases display very similar homotropic allosteric behaviour, but differ extensively in their heterotropic patterns. The ATCase from the thermoacidophilic archaeon Sulfolobus acidocaldarius, for example, is strongly activated by its metabolic pathway's end product CTP, in contrast with Escherichia coli ATCase which is inhibited by CTP. To investigate the structural basis of this property, we have solved the crystal structure of the S. acidocaldarius enzyme in complex with CTP. Structure comparison reveals that effector binding does not induce similar large-scale conformational changes as observed for the E. coli ATCase. However, shifts in sedimentation coefficients upon binding of the bi-substrate analogue PALA show the existence of structurally distinct allosteric states. This suggests that the so-called "Nucleotide-Perturbation model" for explaining heterotropic allosteric behaviour, which is based on global conformational strain, is not a general mechanism of B-class ATCases.

  10. Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase

    DEFF Research Database (Denmark)

    Thymark, Majbritt; Johansson, Eva; Larsen, Sine;

    2007-01-01

    In Escherichia coli and Salmonella typhimurium about 80% of the dUMP used for dTMP synthesis is derived from deamination of dCTP. The dCTP deaminase produces dUTP that subsequently is hydrolyzed by dUTPase to dUMP and diphosphate. The dCTP deaminase is regulated by dTTP that inhibits the enzyme...... of E138D in complex with dUTP showed a hydrogen bonding network in the active site similar to wild-type enzyme. However, changes in the hydrogen bond lengths between the carboxylate and a catalytic water molecule as well as a slightly different orientation of the pyrimidine ring of the bound nucleotide...

  11. Pipeline cost reduction through effective project management and applied technology

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins, A. [TransCanada Pipeline Ltd., Alberta (Canada); Babuk, T. [Empress International Inc., Westwood, NJ (United States); Mohitpour, M. [Tempsys Pipeline Solutions Inc., Vancouver, BC (Canada); Murray, M.A. [National Energy Board of Canada (Canada)

    2005-07-01

    Pipelines are regarded by many as passive structures with the technology involved in their construction and operation being viewed as relatively simple and stable. If such is the case how can there be much room for cost improvement? In reality, there have been many technological and regulatory innovations required within the pipeline industry to meet the challenges posed by ever increasing consumer demand for hydrocarbons, the effects of aging infrastructure and a need to control operating and maintenance expenditures. The importance of technology management, as a subset of overall project management, is a key element of life cycle cost control. Assurance of public safety and the integrity of the system are other key elements in ensuring a successful pipeline project. The essentials of best practise project management from an owner/ operator's perspective are set out in the paper. Particular attention is paid to the appropriate introduction of new technology, strategic procurement practice and material selection, indicating that capital cost savings of up to 15% are achievable without harming life cycle cost. The value of partnering leading to technical innovation, cost savings and improved profitability for all the participants is described. Partnering also helps avoid duplicated effort through the use of common tools for design, planning schedule tracking and reporting. Investing in appropriate technology development has been a major source of cost reduction in recent years and the impact of a number of these recently introduced technologies in the areas of materials, construction processes and operation and maintenance are discussed in the paper. (author)

  12. A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors.

    Science.gov (United States)

    Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, Beatrice S; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanová, Júlia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joel; Manganelli, Riccardo; Mattevi, Andrea; Pasca, Maria Rosalia; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent R

    2017-06-09

    Despite its great potential, the target-based approach has been mostly unsuccessful in tuberculosis drug discovery, while whole cell phenotypic screening has delivered several active compounds. However, for many of these hits, the cellular target has not yet been identified, thus preventing further target-based optimization of the compounds. In this context, the newly validated drug target CTP synthetase PyrG was exploited to assess a target-based approach of already known, but untargeted, antimycobacterial compounds. To this purpose the publically available GlaxoSmithKline antimycobacterial compound set was assayed, uncovering a series of 4-(pyridin-2-yl)thiazole derivatives which efficiently inhibit the Mycobacterium tuberculosis PyrG enzyme activity, one of them showing low activity against the human CTP synthetase. The three best compounds were ATP binding site competitive inhibitors, with Ki values ranging from 3 to 20 μM, but did not show any activity against a small panel of different prokaryotic and eukaryotic kinases, thus demonstrating specificity for the CTP synthetases. Metabolic labeling experiments demonstrated that the compounds directly interfere not only with CTP biosynthesis, but also with other CTP dependent biochemical pathways, such as lipid biosynthesis. Moreover, using a M. tuberculosis pyrG conditional knock-down strain, it was shown that the activity of two compounds is dependent on the intracellular concentration of the CTP synthetase. All these results strongly suggest a role of PyrG as a target of these compounds, thus strengthening the value of this kind of approach for the identification of new scaffolds for drug development.

  13. Space technology and robotics in school projects

    Science.gov (United States)

    Villias, Georgios

    2016-04-01

    Space-related educational activities is a very inspiring and attractive way to involve students into science courses, present them the variety of STEM careers that they can follow, while giving them at the same time the opportunity to develop various practical and communication skills necessary for their future professional development. As part of a large scale extracurricular course in Space Science, Space Technology and Robotics that has been introduced in our school, our students, divided in smaller groups of 3-4 students in each, try to understand the challenges that current and future space exploration is facing. Following a mixture of an inquiry-based learning methodology and hands-on practical activities related with constructions and experiments, students get a glimpse of the pre-mentioned fields. Our main goal is to gain practical knowledge and inspiration from the exciting field of Space, to attain an adequate level of team spirit and effective cooperation, while developing technical and research data-mining skills. We use the following two approaches: 1. Constructive (Technical) approach Designing and constructing various customized robotic machines, that will simulate the future space exploration vehicles and satellites needed to study the atmosphere, surface and subsurface of planets, moons or other planetary bodies of our solar system that have shown some promising indications for the existence of life, taking seriously into account their special characteristics and known existing conditions (like Mars, Titan, Europa & Enceladus). The STEM tools we use are the following: - LEGO Mindstorms: to construct rovers for surface exploration. - Hydrobots: an MIT's SeaPerch program for the construction of submarine semi-autonomous robots. - CanSats: Arduino-based microsatellites able to receive, record & transmit data. - Space balloons: appropriate for high altitude atmospheric measurements & photography. 2. Scientific approach Conducting interesting physics

  14. [Study on CTP production from CMP by beer yeast cell immobilized in PVA].

    Science.gov (United States)

    Yang, Hong-Yi; Qian, Shi-Jun; Li, Gao-Wo

    2007-03-01

    With PVA as the carrier, the frozen beer yeast cells were immobilized for production of CTP from CMP. we explored the optimal condition of the immobilization from the aspects of the type, concentration of the PVA, and the immobilizing methods of cells In all 8 continuous batch of fermentation under the reactional condition of the immobilized cells, the conversion rate of CTP were maintained about 85% - 95%. Moreever, the storage stability of immobilized cells were investigated, and the products was also isolated and identifided by HPLC.

  15. Projects at the Western Environmental Technology Office. Quarterly technical progress report, January 1--March 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    This quarterly report briefly describes recent progress in eight projects. The projects are entitled Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Program; Plasma Projects; Resource Recovery Project; Spray Casting Project; and Watervliet Arsenal Project.

  16. Projects at the Western Environmental Technology Office. Quarterly technical progress report, January 1--March 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    This quarterly report briefly describes recent progress in eight projects. The projects are entitled Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Program; Plasma Projects; Resource Recovery Project; Spray Casting Project; and Watervliet Arsenal Project.

  17. Ubiquitous Learning Project Using Life-Logging Technology in Japan

    Science.gov (United States)

    Ogata, Hiroaki; Hou, Bin; Li, Mengmeng; Uosaki, Noriko; Mouri, Kosuke; Liu, Songran

    2014-01-01

    A Ubiquitous Learning Log (ULL) is defined as a digital record of what a learner has learned in daily life using ubiquitous computing technologies. In this paper, a project which developed a system called SCROLL (System for Capturing and Reusing Of Learning Log) is presented. The aim of developing SCROLL is to help learners record, organize,…

  18. OCTAVIUS: a FP7 project demonstrating CO2 capture technologies

    NARCIS (Netherlands)

    Broutin, P.; Kvamsdal, H.M.; La Marca, C.; Os, P.J. van; Robinson, L.

    2014-01-01

    The OCTAVIUS project (Optimisation of CO2 Capture Technology Allowing Verification and Implementation at Utility Scale) has started on March 1st 2012 for a period of 5 years, as part of the 7th Framework Programme of the European Commission. Gathering 15 European and 2 South African partners,

  19. Proceedings of the Nuclear Criticality Technology and Safety Project Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, R.G. [comp.

    1994-01-01

    This report is the proceedings of the annual Nuclear Criticality Technology and Safety Project (NCTSP) Workshop held in Monterey, California, on April 16--28, 1993. The NCTSP was sponsored by the Department of Energy and organized by the Los Alamos Critical Experiments Facility. The report is divided into six sections reflecting the sessions outlined on the workshop agenda.

  20. OCTAVIUS: a FP7 project demonstrating CO2 capture technologies

    NARCIS (Netherlands)

    Broutin, P.; Kvamsdal, H.M.; La Marca, C.; Os, P.J. van; Robinson, L.

    2014-01-01

    The OCTAVIUS project (Optimisation of CO2 Capture Technology Allowing Verification and Implementation at Utility Scale) has started on March 1st 2012 for a period of 5 years, as part of the 7th Framework Programme of the European Commission. Gathering 15 European and 2 South African partners, OCTAVI

  1. Ubiquitous Learning Project Using Life-Logging Technology in Japan

    Science.gov (United States)

    Ogata, Hiroaki; Hou, Bin; Li, Mengmeng; Uosaki, Noriko; Mouri, Kosuke; Liu, Songran

    2014-01-01

    A Ubiquitous Learning Log (ULL) is defined as a digital record of what a learner has learned in daily life using ubiquitous computing technologies. In this paper, a project which developed a system called SCROLL (System for Capturing and Reusing Of Learning Log) is presented. The aim of developing SCROLL is to help learners record, organize,…

  2. 5th China Fujian Technology And Projects Fair

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The Fifth China (Fujian) Technology and Projects Fair (CFTPF), which was held on June 18-20 in Fuzhou, capital of Fujian Province, proved a big success, allowing an increasing number of businesses to participate and find new opportunities. In three days,

  3. Expert system for economic evaluation of technological projects

    Directory of Open Access Journals (Sweden)

    Bohumil Hlavenka

    2001-01-01

    Full Text Available Apart from the technical level, a basic tool for decision-making and realization of the technical innovation project is also its economic effectiveness. It is assessed by comparing expenses and effects with respect to all-society interests and standards valid in a relevant period for the areas of technology, economy, ecology, safety of work, etc.

  4. Developing Instructional Technology Products Using Effective Project Management Practices

    Science.gov (United States)

    Allen, Stephanie; Hardin, Paul C.

    2008-01-01

    Delivering a successful instructional technology (IT) product depends on more than just having an extremely creative instructional solution or following an instructional systems design (ISD) model. Proper planning, direction, and execution of the project are require, as well. We present a model of management that encompasses the ISD process. Five…

  5. Project to demonstrate key technologies for native medicines

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Aresearch project on the demonstration of key technologies for developing medicines and pharmacy of Chinese minorities will soon be started at the CAS Northwest Institute of Plateau Biology (NWIPB). From 3 to 5 November, 2008, a forum to appraise its implementation approaches was held in Xining, capital of northwest China's Qinghai Province.

  6. Materials Development Program: Ceramic Technology Project bibliography, 1984--1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The Ceramic Technology [for Advanced Heat Engines] Project was begun in 1983 to meet the ceramic materials needs of the companion DOE automotive engine program, the Advanced Gas Turbine (AGT) project, and the Heavy Duty Transport (low-heat-rejection, heavy-duty diesel) project. Goal is to develop an industry technology base for reliable and cost effective ceramics for applications in advanced automotive gas turbine and diesel engines. Research areas were identified following extensive input from industry and academia. Majority of research is done by industry (60%); work is also done at colleges and universities, in-house, and at other national laboratories and government agencies. In the beginning, reliability of ceramic components was the key issue. The reliability issues have largely been met and, at the present time, cost is the driving issue, especially in light of the highly cost-sensitive automotive market. Emphasis of the program has now been shifted toward developing cost-effective ceramic components for high-performance engines in the near-term. This bibliography is a compilation of publications done in conjunction with the Ceramic Technology Project since its beginning. Citations were obtained from reports done by participants in the project. We have tried to limit citations to those published and easily located. The end date of 1992 was selected.

  7. Learning to make technology work - a study of learning in technology demonstration projects

    DEFF Research Database (Denmark)

    Sutherland Olsen, Dorothy; Andersen, Per Dannemand

    2014-01-01

    Building working demonstrations of new technologies within sustainable energy and transport has become an important activity in the move towards a more energy efficient society. The work involved in building these demonstrations is usually organised in a project with a variety of different...... participants, including users. The aim of the project is usually to test the technology and promote changes in users habits, while learning is frequently cited as the main outcome. In this paper we review existing studies of demonstration projects and try to gain an overview of the main aims and effects...

  8. Biomedical Monitoring By A Novel Noncontact Radio Frequency Technology Project

    Science.gov (United States)

    Oliva-Buisson, Yvette J. (Compiler)

    2014-01-01

    The area of Space Health and Medicine is one of the NASA's Space Technology Grand Challenges. Space is an extreme environment which is not conducive to human life. The extraterrestrial environment can result in the deconditioning of various human physiological systems and thus require easy to use physiological monitoring technologies in order to better monitor space crews for appropriate health management and successful space missions and space operations. Furthermore, the Space Technology Roadmap's Technology Area Breakdown Structure calls for improvements in research to support human health and performance (Technology Area 06). To address these needs, this project investigated a potential noncontact and noninvasive radio frequency-based technique of monitoring central hemodynamic function in human research subjects in response to orthostatic stress.

  9. Mechanish of dTTP Inhibition of the Bifunctional dCTP Deaminase:dUTPase Encoded by Mycobacterium tuberculosis

    DEFF Research Database (Denmark)

    Helt, Signe Smedegaard; Thymark, Majbritt; Harris, Pernille;

    2008-01-01

    to be characterised and provides evidence for bifunctionality of dCTP deaminase occurring outside the Archaea kingdom. A steady-state kinetic analysis revealed that the affinity for dCTP and deoxyuridine triphosphate as substrates for the synthesis of deoxyuridine monophosphate were very similar, a result...

  10. Demonstration Project 111, ITS/CVO Technology Truck, Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Gambrell, KP

    2002-01-11

    In 1995, the planning and building processes began to design and develop a mobile demonstration unit that could travel across the nation and be used as an effective outreach tool. In 1997, the unit was completed; and from June 1997 until December 2000, the Federal Highway Administration (FHWA)/Federal Motor Carrier Safety Administration (FMCSA) mobilized the Technology Truck, also known as Demonstration Project No. 111, ''Advanced Motor Carrier Operations and Safety Technologies.'' The project featured the latest available state-of-the-practice intelligent transportation systems (ITS) technologies designed to improve both the efficiency and safety of commercial vehicle operations (CVO). The Technology Truck was designed to inform and educate the motor carrier community and other stakeholders regarding ITS technologies, thus gaining support and buy-in for participation in the ITS program. The primary objective of the project was to demonstrate new and emerging ITS/CVO technologies and programs, showing their impact on motor carrier safety and productivity. In order to meet the objectives of the Technology Truck project, the FHWA/FMCSA formed public/private partnerships with industry and with Oak Ridge National Laboratory to demonstrate and display available ITS/CVO technologies in a cooperative effort. The mobile demonstration unit was showcased at national and regional conferences, symposiums, universities, truck shows and other venues, in an effort to reach as many potential users and decision makers as possible. By the end of the touring phase, the ITS/CVO Technology Truck had been demonstrated in 38 states, 4 Canadian provinces, 88 cities, and 114 events; been toured by 18,099 people; and traveled 115,233 miles. The market penetration for the Technology Truck exceeded 4,000,000, and the website received more than 25,000 hits. In addition to the Truck's visits, the portable ITS/CVO kiosk was demonstrated at 31 events in 23 cites in 15

  11. Ceramic Technology Project semiannual progress report, April 1992--September 1992

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.R.

    1993-07-01

    This project was developed to meet the ceramic technology requirements of the DOE Office of Transportation Systems` automotive technology programs. Significant progress in fabricating ceramic components for DOE, NASA, and DOE advanced heat engine programs show that operation of ceramic parts in high-temperature engines is feasible; however, addition research is needed in materials and processing, design, and data base and life prediction before industry will have a sufficient technology base for producing reliable cost-effective ceramic engine components commercially. A 5-yr project plan was developed, with focus on structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines.

  12. Risk management in methodologies of information technology and communications projects

    Directory of Open Access Journals (Sweden)

    Jonathan Carrillo

    2013-12-01

    Full Text Available (Received: 2013/10/02 - Accepted: 2013/12/13At present there are methodologies that have several alternatives and methods to manage projects of Information and Communication Technologies. However, these do not cover a solution for the technology events that can occur in the industry, government, education, among others. In the technology market there are several models to identify and analyze risks according to relevant aspects of their area of specialty e.g. projects, in software development, communications, information security and business alignment. For this reason, this research conducted an evaluation of risk management activities of the methodologies used mostly to know which of them includes more correspondence with basic elements of IT using a rating scale.

  13. Project Morpheus: Lessons Learned in Lander Technology Development

    Science.gov (United States)

    Olansen, Jon B.; Munday, Stephen R.; Mitchell, Jennifer D.

    2013-01-01

    NASA's Morpheus Project has developed and tested a prototype planetary lander capable of vertical takeoff and landing, that is designed to serve as a testbed for advanced spacecraft technologies. The lander vehicle, propelled by a LOX/Methane engine and sized to carry a 500kg payload to the lunar surface, provides a platform for bringing technologies from the laboratory into an integrated flight system at relatively low cost. Designed, developed, manufactured and operated in-house by engineers at Johnson Space Center, the initial flight test campaign began on-site at JSC less than one year after project start. After two years of testing, including two major upgrade periods, and recovery from a test crash that caused the loss of a vehicle, flight testing will evolve to executing autonomous flights simulating a 500m lunar approach trajectory, hazard avoidance maneuvers, and precision landing, incorporating the Autonomous Landing and Hazard Avoidance (ALHAT) sensor suite. These free-flights are conducted at a simulated planetary landscape built at Kennedy Space Center's Shuttle Landing Facility. The Morpheus Project represents a departure from recent NASA programs and projects that traditionally require longer development lifecycles and testing at remote, dedicated testing facilities. This paper expands on the project perspective that technologies offer promise, but capabilities offer solutions. It documents the integrated testing campaign, the infrastructure and testing facilities, and the technologies being evaluated in this testbed. The paper also describes the fast pace of the project, rapid prototyping, frequent testing, and lessons learned during this departure from the traditional engineering development process at NASA's Johnson Space Center.

  14. Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity

    DEFF Research Database (Denmark)

    Willemoës, Martin; Mølgaard, Anne; Johansson, Eva

    2005-01-01

    of CTP synthase. In the GATase domain of the recently published structures of the Escherichia coli and Thermus thermophilus CTP synthases a loop region immediately proceeding amino acid residues forming the oxy-anion hole and named lid L11 is shown for the latter enzyme to be flexible and change position......GTP is an allosteric activator of CTP synthase and acts to increase the k(cat) for the glutamine-dependent CTP synthesis reaction. GTP is suggested, in part, to optimally orient the oxy-anion hole for hydrolysis of glutamine that takes place in the glutamine amidotransferase class I (GATase) domain...... with lid L11 and indicate that the GTP activation of glutamine dependent CTP synthesis may be explained by structural rearrangements around the oxy-anion hole of the GATase domain...

  15. A Quantitative Study into the Information Technology Project Portfolio Practice: The Impact on Information Technology Project Deliverables

    Science.gov (United States)

    Yu, Wei

    2013-01-01

    This dissertation applied the quantitative approach to the data gathered from online survey questionnaires regarding the three objects: Information Technology (IT) Portfolio Management, IT-Business Alignment, and IT Project Deliverables. By studying this data, this dissertation uncovered the underlying relationships that exist between the…

  16. A Quantitative Study into the Information Technology Project Portfolio Practice: The Impact on Information Technology Project Deliverables

    Science.gov (United States)

    Yu, Wei

    2013-01-01

    This dissertation applied the quantitative approach to the data gathered from online survey questionnaires regarding the three objects: Information Technology (IT) Portfolio Management, IT-Business Alignment, and IT Project Deliverables. By studying this data, this dissertation uncovered the underlying relationships that exist between the…

  17. 77 FR 21540 - Notice of Submission for OMB Review; Federal Student Aid; Comprehensive Transition Programs (CTP...

    Science.gov (United States)

    2012-04-10

    ... Students With Intellectual Disabilities Expenditure Report SUMMARY: The Higher Education Opportunity Act, Public Law 110-315, added provisions for the Higher Education Act, as amended in section 750 and 766 that... CTP Expenditure Report is the tool for reporting the use of these specific funds. DATES: Interested...

  18. Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes

    DEFF Research Database (Denmark)

    Johansson, Eva; Fanø, Mathias; Bynck, Julie H;

    2005-01-01

    dCTP deaminase (EC 3.5.4.13) catalyzes the deamination of dCTP forming dUTP that via dUTPase is the main pathway providing substrate for thymidylate synthase in Escherichia coli and Salmonella typhimurium. dCTP deaminase is unique among nucleoside and nucleotide deaminases as it functions without...

  19. Communication in high technology product development projects:project personnel’s viewpoint for improvement

    OpenAIRE

    Väänänen, M. (Mirja)

    2010-01-01

    Abstract Product development plays a crucial role in the survival of high technology companies. High technology product development projects typically are multi-technical, multicultural, geographically dispersed, inter-connected and organized in a network of companies. These settings pose extra challenges for communication. In this qualitative multiple-case study, communication challenges and possible solutions for developing communication were studied. The empirical data were collect...

  20. The Hyperion Project: Partnership for an Advaned Technology Cluster Testbed

    Energy Technology Data Exchange (ETDEWEB)

    Seager, M; Leininger, M

    2008-04-28

    The Hyperion project offers a unique opportunity to participate in a community-driven testing and development resource at a scale beyond what can be accomplished by one entity alone. Hyperion is a new strategic technology partnership intended to support the member-driven development and testing at scale. This partnership will allow commodity clusters to scale up to meet the growing demands of customers multi-core petascale simulation environments. Hyperion will tightly couple together the outstanding research and development capabilities of Lawrence Livermore National Laboratory with leading technology companies, including Cisco, Data Direct Networks, Dell, Intel, LSI, Mellanox, Qlogic, RedHat, SuperMicro and Sun. The end goal of this project is to revolutionize cluster computing in fundamental ways by providing the critical software and hardware components for a highly scalable simulation environment. This environment will include support for high performance networking, parallel file systems, operating system, and cluster management. This goal will be achieved by building a scalable technology cluster testbed that will be fully dedicated to the partners and provide: (1) A scalable development testing and benchmarking environment for critical enabling Linux cluster technologies; (2) An evaluation testbed for new hardware and software technologies; and (3) A vehicle for forming long term collaborations.

  1. Scene projection technology development for imaging sensor testing at AEDC

    Science.gov (United States)

    Lowry, H.; Fedde, M.; Crider, D.; Horne, H.; Bynum, K.; Steely, S.; Labello, J.

    2012-06-01

    Arnold Engineering Development Center (AEDC) is tasked with visible-to-LWIR imaging sensor calibration and characterization, as well as hardware-in-the-loop (HWIL) testing with high-fidelity complex scene projection to validate sensor mission performance. They are thus involved in the development of technologies and methodologies that are used in space simulation chambers for such testing. These activities support a variety of program needs such as space situational awareness (SSA). This paper provides an overview of pertinent technologies being investigated and implemented at AEDC.

  2. Technology Applications Group Multimedia CD-ROM Project

    Science.gov (United States)

    McRacken, Kristi D.

    1995-01-01

    To produce a multimedia CD-ROM for the Technology Applications Group which would present the Technology Opportunity Showcase (TOPS) exhibits and Small Business Innovative Research (SBIR) projects to interested companies. The CD-ROM format is being used and developed especially for those companies who do not have Internet access, and cannot directly visit Langley through the World Wide Web. The CD-ROM will include text, pictures, sound, and movies. The information for the CD-ROM will be stored in a database from which the users can query and browse the information, and future CD's can be maintained and updated.

  3. Gas-turbine critical research and advanced technology support project

    Science.gov (United States)

    Clark, J. S.; Lowell, C. E.; Niedzwiecki, R. W.; Nainiger, J. J.

    1979-01-01

    The technical progress made during the first 15 months of a planned 40-month project to provide a critical-technology data base for utility gas-turbine systems capable of burning coal-derived fuels is summarized. Tasks were included in the following areas: (1) combustion, to study the combustion of coal-derived fuels and conversion of fuel-bound nitrogen to NOx; (2) materials, to understand and prevent hot corrosion; and (3) system studies, to integrate and guide the other technologies. Significant progress was made.

  4. OPTIMIZING OUTCOME IN THE UNIVERSITY-INDUSTRY TECHNOLOGY TRANSFER PROJECTS

    Directory of Open Access Journals (Sweden)

    Hamed ALAVI

    2016-04-01

    Full Text Available Transferring inventions of academic scientists to private enterprises for the purpose of commercialization is long known as University-Industry (firm Technology Transfer While the importance of this phenomenon is simultaneously raising in public and private sector, only a part of patented academic inventions succeed in passing the process of commercialization. Despite the fact that formal Technology Transfer process and licencing of patented innovations to third party is the main legal tool for safeguarding rights of academic inventors in commercialization of their inventions, it is not sufficient for transmitting tacit knowledge which is necessary in exploitation of transferred technology. Existence of reciprocal and complementary relations between formal and informal technology transfer process has resulted in formation of different models for university-industry organizational collaboration or even integration where licensee firms keep contact with academic inventors after gaining legal right for commercialization of their patented invention. Current paper argues that despite necessity for patents to legally pass the right of commercialization of an invention, they are not sufficient for complete knowledge transmission in the process of technology transfer. Lack of efficiency of formal mechanism to end the Technology Transfer loop makes an opportunity to create innovative interpersonal and organizational connections among patentee and licensee company. With emphasize on need for further elaboration of informal mechanisms as critical and underappreciated aspect of technology transfer process, article will try to answer the questions of how to optimize knowledge transmission process in the framework of University-Industry Technology Transfer Projects? What is the theoretical basis for university-industry technology transfer process? What are organization collaborative models which can enhance overall performance by improving transmission of

  5. Implementation of Relevant Methods in Assessing Traffic-Technological Projects

    Directory of Open Access Journals (Sweden)

    Danijela Barić

    2007-09-01

    Full Text Available The assessment of investment traffic-technological projectsmeans a set of activities whose basic aim is to determine the justificationand feasibility of the projects. The decision-makingprocess, including the decision-making on investments is an extremelycomplex process, and the decision-maker has to have avision of the future and make decisions accordingly in a modemand flexible manner. Therefore, the decisions need to be theresult of a planning and research process based on relevant scientificmethods. The work includes the selected, analysed andpresented methods of cost-benefit analysis, methods of multi-criteria decision-making and SWOT (Strengths, Weaknesses,Opportunities, and Threats analysis methods. Regarding thebasic characteristics, the mentioned methods have been compared,the order of their implementation has been determined,and then they have been implemented in assessing the traffic-technological projects of reconstmction with the aim of selectingthe optimal variant solution.

  6. Technology and commercial supply of components for the LHC project

    CERN Document Server

    Faugeras, Paul E

    1998-01-01

    After a brief reminder of the motives and the outline of the Large Hadron Collider (LHC) project, one will review the technology and the hardware to be built up. The LHC calls for High Tech innovation s in superconductivity, cryogenics with superfluid helium, ultra high vacuum, surface treatments, etc. which have to be transferred to Industry and produced on a large scale. It will also make extensi ve use of more conventional technology, but because of the intrinsic complexity of the machine and of the international nature of its funding and procurement sources, it will require sophisticated man agement and logistics tools to minimize costs and installation time. The planning for the whole project will be given with an indication of the nature and time schedule of the major contracts.

  7. A Tailored Systems Engineering Framework for Science and Technology Projects

    Science.gov (United States)

    2009-03-01

    developments, and maybe even humanity’s grand challenges [ NAE , 2008]) and allows scientists, technologists, engineers, and project managers the opportunity...application (in which case the process is usually executed at the TD level), or cross- and multi-discipline technology solutions (executed at the enterprise...E. Director, United States Air Force Center for Systems Engineering, Wright-Patterson AFB OH. Personal Interview. 21 July 2008. [ NAE , 2008

  8. ECUT (Energy Conversion and Utilization Technologies) program: Biocatalysis project

    Science.gov (United States)

    Baresi, Larry

    1989-03-01

    The Annual Report presents the fiscal year (FY) 1988 research activities and accomplishments, for the Biocatalysis Project of the U.S. Department of Energy, Energy Conversion and Utilization Technologies (ECUT) Division. The ECUT Biocatalysis Project is managed by the Jet Propulsion Laboratory, California Institute of Technology. The Biocatalysis Project is a mission-oriented, applied research and exploratory development activity directed toward resolution of the major generic technical barriers that impede the development of biologically catalyzed commercial chemical production. The approach toward achieving project objectives involves an integrated participation of universities, industrial companies and government research laboratories. The Project's technical activities were organized into three work elements: (1) The Molecular Modeling and Applied Genetics work element includes research on modeling of biological systems, developing rigorous methods for the prediction of three-dimensional (tertiary) protein structure from the amino acid sequence (primary structure) for designing new biocatalysis, defining kinetic models of biocatalyst reactivity, and developing genetically engineered solutions to the generic technical barriers that preclude widespread application of biocatalysis. (2) The Bioprocess Engineering work element supports efforts in novel bioreactor concepts that are likely to lead to substantially higher levels of reactor productivity, product yields and lower separation energetics. Results of work within this work element will be used to establish the technical feasibility of critical bioprocess monitoring and control subsystems. (3) The Bioprocess Design and Assessment work element attempts to develop procedures (via user-friendly computer software) for assessing the energy-economics of biocatalyzed chemical production processes, and initiation of technology transfer for advanced bioprocesses.

  9. NASA Fixed Wing Project: Green Technologies for Future Aircraft Generation

    Science.gov (United States)

    Del Rosario, Ruben; Koudelka, John M.; Wahls, Rich; Madavan, Nateri

    2014-01-01

    Commercial aviation relies almost entirely on subsonic fixed wing aircraft to constantly move people and goods from one place to another across the globe. While air travel is an effective means of transportation providing an unmatched combination of speed and range, future subsonic aircraft must improve substantially to meet efficiency and environmental targets.The NASA Fundamental Aeronautics Fixed Wing (FW) Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. Multidisciplinary advances are required in aerodynamic efficiency to reduce drag, structural efficiency to reduce aircraft empty weight, and propulsive and thermal efficiency to reduce thrust-specific energy consumption (TSEC) for overall system benefit. Additionally, advances are required to reduce perceived noise without adversely affecting drag, weight, or TSEC, and to reduce harmful emissions without adversely affecting energy efficiency or noise.The paper will highlight the Fixed Wing project vision of revolutionary systems and technologies needed to achieve these challenging goals. Specifically, the primary focus of the FW Project is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe

  10. Development of oral CTL vaccine using a CTP-integrated Sabin 1 poliovirus-based vector system.

    Science.gov (United States)

    Han, Seung-Soo; Lee, Jinjoo; Jung, Yideul; Kang, Myeong-Ho; Hong, Jung-Hyub; Cha, Min-Suk; Park, Yu-Jin; Lee, Ezra; Yoon, Cheol-Hee; Bae, Yong-Soo

    2015-09-11

    We developed a CTL vaccine vector by modification of the RPS-Vax system, a mucosal vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1 p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically stable and efficiently induced Th1 immunity and p24-specific CTLs in immunized poliovirus receptor-transgenic (PVR-Tg) mice. In challenge experiments, PVR-Tg mice that were pre-immunized orally with vRPS-CTP/p24 were resistant to challenge with a lethal dose of p24-expressing recombinant vaccinia virus (rMVA-p24). These results suggested that the RPS-CTP vector system had potential for developing oral CTL vaccines against infectious diseases.

  11. Bringing technology to students’ proximity: a sociocultural account of technology-based learning projects

    OpenAIRE

    Evode Mukama

    2014-01-01

    This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs) through a sociocultural perspective. The methodology included focus-group discussions and field notes to collect empirical data. The findings reveal that the more educational technologies capture objects of learning positioned in the students’ ...

  12. Implementing Biogas Technology Project in Malvar, Batangas, Philippines

    Directory of Open Access Journals (Sweden)

    Juvy G. Mojares

    2015-11-01

    Full Text Available This study sought to determine the environmental and social impacts of the biogas technology project of the municipal government of Malvar, Batangas, Philippines, through the Municipal Environment and Natural Resources Office. Document analysis and interview were employed in this study. Results showed that heat and electricity generation from biogas decreased dependency on electricity and fuel oil.In terms of social impacts, the biogas technology contributed to socio-economic improvement of the barangay in the form of job creation, technological and skills transfer through training in biogas production, contribution to continuous pursuing of energy neutrality and encouraged sustainability development at the community level. Aside from these, the technology was a source of organic fertilizer for the farming community of Malvar. It is recommended that commercial farms be strictly monitored and ordinances be imposed on them specifically on the use of biogas technology. The municipal government could partner with GOs and NGOs providing grant or equipment for such technology. For the monitoring of backyard farms, develop close coordination with barangay officials, if it does not work, plan a consultative meeting with agencies concerned to explain the hazards of improper disposal of hog wastes.

  13. Waste-to-energy technologies and project implementation

    CERN Document Server

    Rogoff, Marc J

    2011-01-01

    This book covers in detail programs and technologies for converting traditionally landfilled solid wastes into energy through waste-to-energy projects. Modern Waste-to-Energy plants are being built around the world to reduce the levels of solid waste going into landfill sites and contribute to renewable energy and carbon reduction targets. The latest technologies have also reduced the pollution levels seen from early waste incineration plants by over 99 per cent. With case studies from around the world, Rogoff and Screve provide an insight into the different approaches taken to the planning and implementation of WTE. The second edition includes coverage of the latest technologies and practical engineering challenges as well as an exploration of the economic and regulatory context for the development of WTE.

  14. Pilot Project Technology Business Case: Mobile Work Packages

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lawrie, Sean [ScottMadden, Inc., Raleigh, NC (United States); Niedermuller, Josef [ScottMadden, Inc., Raleigh, NC (United States)

    2015-05-01

    Performance advantages of the new pilot project technologies are widely acknowledged, but it has proven difficult for utilities to derive business cases for justifying investment in these new capabilities. Lack of a business case is often cited by utilities as a barrier to pursuing wide-scale application of digital technologies to nuclear plant work activities. The decision to move forward with funding usually hinges on demonstrating actual cost reductions that can be credited to budgets and thereby truly reduce O&M or capital costs. Technology enhancements, while enhancing work methods and making work more efficient, often fail to eliminate workload such that it changes overall staffing and material cost requirements. It is critical to demonstrate cost reductions or impacts on non-cost performance objectives in order for the business case to justify investment by nuclear operators. The Business Case Methodology (BCM) was developed in September of 2015 to frame the benefit side of II&C technologies to address the “benefit” side of the analysis—as opposed to the cost side—and how the organization evaluates discretionary projects (net present value (NPV), accounting effects of taxes, discount rates, etc.). The cost and analysis side is not particularly difficult for the organization and can usually be determined with a fair amount of precision (not withstanding implementation project cost overruns). It is in determining the “benefits” side of the analysis that utilities have more difficulty in technology projects and that is the focus of this methodology. The methodology is presented in the context of the entire process, but the tool provided is limited to determining the organizational benefits only. This report describes a the use of the BCM in building a business case for mobile work packages, which includes computer-based procedures and other automated elements of a work package. Key to those impacts will be identifying where the savings are

  15. 76 FR 12507 - Science and Technology Reinvention Laboratory Personnel Management Demonstration Project...

    Science.gov (United States)

    2011-03-07

    ... Secretary Science and Technology Reinvention Laboratory Personnel Management Demonstration Project... monitor the fair, equitable, and consistent implementation of the provisions of the demonstration project... March 7, 2011 Part III Department of Defense Science and Technology Reinvention Laboratory...

  16. Projects at the Western Environmental Technology Office. Quarterly technical progress report, April 1--June 30, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This report contains brief outlines of the multiple projects under the responsibility of the Western Environmental Technology Office in Butte Montana. These projects include biomass remediation, remediation of contaminated soils, mine waste technology, and several other types of remediation.

  17. Local participation in complex technological projects as bridging between different communities in Belgium

    NARCIS (Netherlands)

    Sips, K.; Craps, M.; Dewulf, A.

    2013-01-01

    Local community participation in complex technological projects, where technological innovations and risks need to be managed, is notoriously challenging. Relations with local inhabitants easily take the form of exclusion, protest, controversy or litigation. While such projects represent

  18. Bringing Technology to Students' Proximity: A Sociocultural Account of Technology-Based Learning Projects

    Science.gov (United States)

    Mukama, Evode

    2014-01-01

    This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs) through a sociocultural perspective. The methodology included focus group discussions and field…

  19. Bringing Technology to Students’ Proximity: A Sociocultural Account of Technology-Based Learning Projects

    Directory of Open Access Journals (Sweden)

    Evode Mukama

    2014-12-01

    Full Text Available This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs through a sociocultural perspective. The methodology included focus-group discussions and field notes to collect empirical data. The findings reveal that the more educational technologies capture objects of learning positioned in the students’ sociocultural proximity, the more focused the learners’ attention is on these objects. The study shows also that a change in learning projects may depend to a large extent on whether the technology relates to the students’ sociocultural proximity, that is, taking into consideration students’ physical, cultural, and contextual real world. The study recommends a community of learning/inquiry embedded in a collaborative, problem-solving dynamic involving cognitive support from peers, teachers, external specialists, and the wider community.

  20. Technical cooperation front line. JICA technology cooperation project in Indonesia and Vietnam (Coal mining technology enhancement project in Indonesia); (Coal Mine Firedamp Gas Management Center in Vietnam)

    Energy Technology Data Exchange (ETDEWEB)

    Inami, K. [Japan Coal Energy Center (Japan). Technical Service Group, Engineering Dept.

    2002-09-01

    In April 2001, two coal mining technical cooperation projects of Japan International Cooperation Agency (JICA) started. The first project is 'Coal Mining Technology Enhancement Project in Indonesia'. The second project is 'Coal Mine Firedamp Gas Management Center in Vietnam'. Both are project-type technical cooperation for the technology transfer centering in advanced Japanese underground coal mine technologies for a five years project period from April 1 2001 to 31 March 2006. Japan Coal Energy Center (JCOAL) have carried out indirect supporting function for the planning and the execution of the project from the preparation phase of the project start-up as a supporting agency based on the business agreement with JICA. This paper reports the projects development. 2 figs., 1 tab.

  1. Laboratory technology research - abstracts of FY 1997 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

  2. Efficacy and safety of switching from reference infliximab to CT-P13 compared with maintenance of CT-P13 in ankylosing spondylitis: 102-week data from the PLANETAS extension study

    Science.gov (United States)

    Park, Won; Yoo, Dae Hyun; Miranda, Pedro; Brzosko, Marek; Wiland, Piotr; Gutierrez-Ureña, Sergio; Mikazane, Helena; Lee, Yeon-Ah; Smiyan, Svitlana; Lim, Mie-Jin; Kadinov, Vladimir; Abud-Mendoza, Carlos; Kim, HoUng; Lee, Sang Joon; Bae, YunJu; Kim, SuYeon; Braun, Jürgen

    2017-01-01

    Objectives To investigate the efficacy and safety of switching from infliximab reference product (RP) to its biosimilar or maintaining biosimilar treatment in patients with ankylosing spondylitis (AS). Methods This open-label extension study recruited patients with AS who completed a 54-week, randomised controlled study comparing CT-P13 with RP (PLANETAS). CT-P13 (5 mg/kg) was administered intravenously every 8 weeks from week 62 to week 102. Efficacy end points included the proportion of patients achieving Assessment of SpondyloArthritis international Society (ASAS)20. Antidrug antibodies (ADAs) were measured using an electrochemiluminescent method. Data were analysed for patients treated with CT-P13 in the main PLANETAS study and the extension (maintenance group) and those who were switched to CT-P13 during the extension study (switch group). Results Overall, 174 (82.9%) of 210 patients who completed the first 54 weeks of PLANETAS and agreed to participate in the extension were enrolled. Among these, 88 were maintained on CT-P13 and 86 were switched to CT-P13 from RP. In these maintenance and switch groups, respectively, ASAS20 response rates at week 102 were 80.7% and 76.9%. ASAS40 and ASAS partial remission were also similar between groups. ADA positivity rates were comparable (week 102: 23.3% vs 27.4%). Adverse events led to treatment discontinuation during the extension study in 3 (3.3%) and 4 (4.8%) patients, respectively. Conclusions This is the first study to show that switching from RP to its biosimilar CT-P13 is possible without negative effects on safety or efficacy in patients with AS. In the maintenance group, CT-P13 was effective and well tolerated over 2 years of treatment. Trial registration number NCT01571206; Results. PMID:27117698

  3. Crystallization and preliminary X-ray analysis of CTP:phosphoethanolamine cytidylyltransferase (ECT) from Saccharomyces cerevisiae

    Energy Technology Data Exchange (ETDEWEB)

    Ohtsuka, Jun; Nagata, Koji; Lee, Woo Cheol [Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657 (Japan); Ono, Yusuke; Fukuda, Ryouichi; Ohta, Akinori [Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657 (Japan); Tanokura, Masaru, E-mail: amtanok@mail.ecc.u-tokyo.ac.jp [Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657 (Japan)

    2006-10-01

    CTP:phosphoethanolamine cytidylyltransferase from S. cerevisiae has been expressed, purified and crystallized. CTP:phosphoethanolamine cytidylyltransferase (ECT) is the enzyme that catalyzes the conversion of phosphoethanolamine to CDP-ethanolamine in the phosphatidylethanolamine-biosynthetic pathway (Kennedy pathway). ECT from Saccharomyces cerevisiae was crystallized by the sitting-drop vapour-diffusion method using PEG 4000 as precipitant. The crystals diffracted X-rays from a synchrotron-radiation source to 1.88 Å resolution. The space group was assigned as primitive tetragonal, P4{sub 1}2{sub 1}2 or P4{sub 3}2{sub 1}2, with unit-cell parameters a = b = 66.3, c = 150.8 Å. The crystals contain one ECT molecule in the asymmetric unit (V{sub M} = 2.2 Å{sup 3} Da{sup −1}), with a solvent content of 43%.

  4. Assessment of urgent impacts of greenhouse gas emissions—the climate tipping potential (CTP)

    DEFF Research Database (Denmark)

    Jørgensen, Susanne Vedel; Hauschild, Michael Zwicky; Nielsen, Per H.

    2014-01-01

    The impact of anthropogenic greenhouse gas (GHG) emissions on climate change receives much focus today. This impact is however often considered only in terms of global warming potential (GWP), which does not take into account the need for staying below climatic target levels, in order to avoid...... passing critical climate tipping points. Some suggestions to include a target level in climate change impact assessment have been made, but with the consequence of disregarding impacts beyond that target level. The aim of this paper is to introduce the climate tipping impact category, which represents...... the climate tipping potential (CTP) of GHG emissions relative to a climatic target level. The climate tipping impact category should be seen as complementary to the global warming impact category.The CTP of a GHG emission is expressed as the emission’s impact divided by the ‘capacity’ of the atmosphere...

  5. Technology Base Research Project for electrochemical energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, Kim (ed.)

    1991-06-01

    The US DOE's Office of Propulsion Systems provides support for an electrochemical energy storage program, which includes R D on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EVs). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The general R D areas addressed by the project include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, establishment of engineering principles applicable to electrochemical energy storage and conversion, and the development of air-system (fuel cell, metal/air) technology for transportation applications. Major emphasis is given to applied research which will lead to superior performance and lower life-cycle costs. The TBR Project is divided into three major project elements: Exploratory Research, Applied Science Research, and Air Systems Research. Highlights of each project element are summarized according to the appropriate battery system or electrochemical research area. 16 figs., 4 tabs.

  6. Laboratory technology research: Abstracts of FY 1998 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of the country: the world-class basic research capability of the DOE Office of Science (SC) national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program in FY 1998 explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing and manufacturing research, and environmental and biomedical research. Abstracts for 85 projects are contained in this report.

  7. An evaluation approach for research project pilot technological applications

    Science.gov (United States)

    Marcelino-Jesus, Elsa; Sarraipa, Joao; Jardim-Goncalves, Ricardo

    2013-10-01

    In a world increasingly more competitive and in a constantly development and growth it's important that companies have economic tools, like frameworks to help them to evaluate and validate the technology development to better fits in each company particular needs. The paper presents an evaluation approach for research project pilot applications to stimulate its implementation and deployment, increasing its adequacy and acceptance to their stakeholders and consequently providing new business profit and opportunities. Authors used the DECIDE evaluation framework as a major guide to this approach, which was tested in the iSURF project to support the implementation of an interoperability service utility for collaborative supply chain planning across multiple domains supported by RFID devices.

  8. Laboratory Technology Research: Abstracts of FY 1996 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program are conducted by the five ER multi-program laboratories: Argonne, Brookhaven, Lawrence Berkeley, Oak Ridge, and Pacific Northwest National Laboratories. These projects explore the applications of basic research advances relevant to Department of Energy`s (DOE) mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing/manufacturing research, and sustainable environments.

  9. Monitoring ATLAS L1 CTP data from P-BEAST

    CERN Document Server

    Roggel, Jens

    2017-01-01

    The ATLAS Level-1 Central Trigger Processor combines information from the calori-meters and the muon detectors and takes a decision to accept an event based on a list of selection criteria (trigger items). Busy signals from the detectors and generated dead time by the Central Trigger Processor prevents the buffers to become full. The visualisation of this data is useful to check the functionality of the system. My project during the CERN summer student programme was to develop an application, which produces plots of relevant Central Trigger Processor data and presents the results in an appropriate format for experts and users.

  10. Exploring the Relationship between Authentic Leadership and Project Outcomes and Job Satisfaction with Information Technology Professionals

    Science.gov (United States)

    Fischer, Mark A.

    2014-01-01

    One of the most important issues for organizations and information technology (IT) professionals is measuring the success or failure of information technology projects. How we understand the value and usefulness of IT projects is critical to how information technology executives evaluate and decide on technology investments. In a 2009 CHAOS…

  11. Exploring the Relationship between Authentic Leadership and Project Outcomes and Job Satisfaction with Information Technology Professionals

    Science.gov (United States)

    Fischer, Mark A.

    2014-01-01

    One of the most important issues for organizations and information technology (IT) professionals is measuring the success or failure of information technology projects. How we understand the value and usefulness of IT projects is critical to how information technology executives evaluate and decide on technology investments. In a 2009 CHAOS…

  12. 1990 DOE/SANDIA crystalline photovoltaic technology project review meeting

    Energy Technology Data Exchange (ETDEWEB)

    Ruby, D.S. (ed.)

    1990-07-01

    This document serves as the proceedings for the annual project review meeting held by Sandia's Photovoltaic Cell Research Division and Photovoltaic Technology Division. It contains information supplied by each organization making a presentation at the meeting, which was held August 7 through 9, 1990 at the Sheraton Hotel in Albuquerque, New Mexico. Sessions were held to discuss national photovoltaic programs, one-sun crystalline silicon cell research, concentrator silicon cell research, concentrator 3-5 cell research, and concentrating collector development.

  13. 1992 DOE/Sandia crystalline photovoltaic technology project review meeting

    Energy Technology Data Exchange (ETDEWEB)

    Maish, A. [ed.

    1992-07-01

    This document serves as the proceedings for the annual project review meeting held by Sandia National Laboratories` Photovoltaic Technology and Photovoltaic Evaluation Departments. It contains information supplied by organizations making presentations at the meeting, which was held July 14--15, 1992 at the Sheraton Old Town Hotel in Albuquerque, New Mexico. Overview sessions covered the Department of Energy (DOE) program, including those at Sandia and the National Renewable Energy Laboratory (NREL), and non-DOE programs, including the EPRI concentrator collector program, The Japanese crystalline silicon program, and some concentrating photovoltaic activities in Europe. Additional sessions included papers on Sandia`s Photovoltaic Device Fabrication Laboratory`s collaborative research, cell processing research, the activities of the participants in the Concentrator Initiative Program, and photovoltaic technology evaluation at Sandia and NREL.

  14. The Advanced Linked Extended Reconnaissance & Targeting Technology Demonstration project

    Science.gov (United States)

    Edwards, Mark

    2008-04-01

    The Advanced Linked Extended Reconnaissance & Targeting (ALERT) Technology Demonstration (TD) project is addressing many operational needs of the future Canadian Army's Surveillance and Reconnaissance forces. Using the surveillance system of the Coyote reconnaissance vehicle as an experimental platform, the ALERT TD project aims to significantly enhance situational awareness by fusing multi-sensor and tactical data, developing automated processes, and integrating beyond line-of-sight sensing. The project is exploiting important advances made in computer processing capability, displays technology, digital communications, and sensor technology since the design of the original surveillance system. As the major research area within the project, concepts are discussed for displaying and fusing multi-sensor and tactical data within an Enhanced Operator Control Station (EOCS). The sensor data can originate from the Coyote's own visible-band and IR cameras, laser rangefinder, and ground-surveillance radar, as well as from beyond line-of-sight systems such as mini-UAVs and unattended ground sensors. Video-rate image processing has been developed to assist the operator to detect poorly visible targets. As a second major area of research, automatic target cueing capabilities have been added to the system. These include scene change detection, automatic target detection and aided target recognition algorithms processing both IR and visible-band images to draw the operator's attention to possible targets. The merits of incorporating scene change detection algorithms are also discussed. In the area of multi-sensor data fusion, up to Joint Defence Labs level 2 has been demonstrated. The human factors engineering aspects of the user interface in this complex environment are presented, drawing upon multiple user group sessions with military surveillance system operators. The paper concludes with Lessons Learned from the project. The ALERT system has been used in a number of C4ISR

  15. NASA's Exploration Technology Development Program Energy Storage Project Battery Technology Development

    Science.gov (United States)

    Reid, Concha M.; Miller, Thomas B.; Mercer, Carolyn R.; Jankovsky, Amy L.

    2010-01-01

    Technical Interchange Meeting was held at Saft America s Research and Development facility in Cockeysville, Maryland on Sept 28th-29th, 2010. The meeting was attended by Saft, contractors who are developing battery component materials under contracts awarded through a NASA Research Announcement (NRA), and NASA. This briefing presents an overview of the components being developed by the contractor attendees for the NASA s High Energy (HE) and Ultra High Energy (UHE) cells. The transition of the advanced lithium-ion cell development project at NASA from the Exploration Technology Development Program Energy Storage Project to the Enabling Technology Development and Demonstration High Efficiency Space Power Systems Project, changes to deliverable hardware and schedule due to a reduced budget, and our roadmap to develop cells and provide periodic off-ramps for cell technology for demonstrations are discussed. This meeting gave the materials and cell developers the opportunity to discuss the intricacies of their materials and determine strategies to address any particulars of the technology.

  16. A Project in Support of Nuclear Technology Cooperation

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Young Cheol; Kim, Kyoung Pyo; Yi, Ji Ho (and others)

    2007-12-15

    The results and contents of the project are as follows; - Establish strategies of international cooperation in an effort to promote our nation's Leading role in international society, to form the foundation for the effective transfer of nuclear technology to developing countries, and to cope with the rapidly changing international nuclear climate. - Domestic INIS project has carried out various activities on supporting a decision-making for INIS Secretariat, exchanges of the statistical information between INIS and the country, and technical assistance for domestic end-users using INIS database. - Based on the construction of INIS database sent by member states, the data published in the country has been gathered, collected, and inputted to INIS database according to the INIS reference series. - Using the INIS output data, it has provided domestic users with searching INIS CD-ROM DB and INIS online database, INIS SDI service, non-conventional literature delivery services and announce INIS to users. - Establish the integrated management system of information resources and to automate business flow and to improve business productivity through efficient information sharing. - Promotion of domestic nuclear energy technology by utilizing nuclear energy information and computer software developed in the advanced countries.

  17. Benefits from the U.S. photovoltaic manufacturing technology project

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, R.L.; Witt, C.E.; Thomas, H.P. [National Renewable Energy Lab., Golden, CO (United States)] [and others

    1996-05-01

    This paper examines the goals of the Photovoltaic Manufacturing Technology (PVMaT) project and its achievements in recapturing the investment by the photovoltaic (PV) industry and the public in this research. The PVMaT project was initiated in 1990 with the goal of enhancing the world-wide competitiveness of the U.S. PV industry. Based on the authors analysis, PVMaT has contributed to PV module manufacturing process improvements, increased product value, and reductions in the price of today`s PV products. An evaluation of success in this project was conducted using data collected from 10 of the PVMaT industrial participants in late fiscal year (FY) 1995. These data indicate a reduction of 56% in the weighted average module manufacturing costs from 1992 to 1996. During this same period, U.S. module manufacturing capacity has increased by more than a factor of 6. Finally, the analysis indicates that both the public and the manufacturers will recapture the funds expended in R&D manufacturing improvements well before the year 2000.

  18. Evaluation of Representative Smart Grid Investment Grant Project Technologies: Thermal Energy Storage

    Energy Technology Data Exchange (ETDEWEB)

    Tuffner, Francis K.; Bonebrake, Christopher A.

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of energy storage technologies deployed in the SGIG projects.

  19. Using Information and Communication Technologies in Hospital Classrooms: SAVEH Project

    Directory of Open Access Journals (Sweden)

    Dolores Meneses

    2011-03-01

    Full Text Available Children suffering a serious illness, experience enormous changes in their daily lives. Not only does the direct consequences of the disease affect the child, but also the fact of being at a hospital, or at home and not being allowed to go to school. Frequently, connections with classmates, neighbors, and sometimes even some with his relatives are lost. Furthermore, the responsibility of the state, to continue his schooling process is much harder, since different communities (family, school teachers, hospital teachers, medical doctors, psychologists… have to be coordinated. Last but not least, entertainment and enjoyment should be provided to avoid boredom and to improve their affective state. At the same time, with the development of Information and Communication Technologies, a large number of solutions have arisen that allow people to enhance their communication, education and entertainment possibilities. These technologies seem perfectly suitable to be used to tackle the problems described above. In this article, some of the special necessities of children suffering from a serious illness are pointed out, technologies available to be facilitated are described and some initiatives taking place in Spain mentioned. The SAVEH project will be described in detail.

  20. Flexible Electrostatic Technology for Capture and Handling Project

    Science.gov (United States)

    Keys, Andrew; Bryan, Tom; Horwitz, Chris; Rakoczy, John; Waggoner, Jason

    2015-01-01

    previous MSFC and NASA proposals or concepts can now be realized or simplified by the development of the this initial and future FETCH grippers including commercial resupply, Exploration vehicle assembly, Satellite servicing, and orbital debris removal since a major part of these missions is to align to and capture some handle. Completed Project (2013 - 2014) Flexible Electrostatic Technology for Capture & Handling Project Center Innovation Fund: MSFC CIF Program | Space Technology Mission Directorate (STMD) For more information visit techport.nasa.gov Some NASA technology projects are smaller (for example SBIR/STTR, NIAC and Center Innovation Fund), and will have less content than other, larger projects. Newly created projects may not sensors or injection of permanent adhesives. With gripping forces estimated between 0.5 and 2.5 pounds per square inch or 70-300 lb./sq. ft. of surface contact, the FETCH can turn-on and turn-off rapidly and repeatedly to enable sample handling, soft docking, in-space assembly, and precision relocation for accurate anchor adhesion.

  1. Gas Dynamic Spray Technology Demonstration Project Management. Joint Test Report

    Science.gov (United States)

    Lewis, Pattie

    2011-01-01

    The standard practice for protecting metallic substrates in atmospheric environments is the use of an applied coating system. Current coating systems used across AFSPC and NASA contain volatile organic compounds (VOCs) and hazardous air pollutants (HAPs). These coatings are sUbject to environmental regulations at the Federal and State levels that limit their usage. In addition, these coatings often cannot withstand the high temperatures and exhaust that may be experienced by Air Force Space Command (AFSPC) and NASA structures. In response to these concerns, AFSPC and NASA have approved the use of thermal spray coatings (TSCs). Thermal spray coatings are extremely durable and environmentally friendly coating alternatives, but utilize large cumbersome equipment for application that make the coatings difficult and time consuming to repair. Other concerns include difficulties coating complex geometries and the cost of equipment, training, and materials. Gas Dynamic Spray (GOS) technology (also known as Cold Spray) was evaluated as a smaller, more maneuverable repair method as well as for areas where thermal spray techniques are not as effective. The technology can result in reduced maintenance and thus reduced hazardous materials/wastes associated with current processes. Thermal spray and GOS coatings also have no VOCs and are environmentally preferable coatings. The primary objective of this effort was to demonstrate GDS technology as a repair method for TSCs. The aim was that successful completion of this project would result in approval of GDS technology as a repair method for TSCs at AFSPC and NASA installations to improve corrosion protection at critical systems, facilitate easier maintenance activity, extend maintenance cycles, eliminate flight hardware contamination, and reduce the amount of hazardous waste generated.

  2. The Learning Process and Technological Change in Wind Power: Evidence from China's CDM Wind Projects

    Science.gov (United States)

    Tang, Tian; Popp, David

    2016-01-01

    The Clean Development Mechanism (CDM) is a project-based carbon trade mechanism that subsidizes the users of climate-friendly technologies and encourages technology transfer. The CDM has provided financial support for a large share of Chinese wind projects since 2002. Using pooled cross-sectional data of 486 registered CDM wind projects in China…

  3. The Learning Process and Technological Change in Wind Power: Evidence from China's CDM Wind Projects

    Science.gov (United States)

    Tang, Tian; Popp, David

    2016-01-01

    The Clean Development Mechanism (CDM) is a project-based carbon trade mechanism that subsidizes the users of climate-friendly technologies and encourages technology transfer. The CDM has provided financial support for a large share of Chinese wind projects since 2002. Using pooled cross-sectional data of 486 registered CDM wind projects in China…

  4. Factors that Impact Software Project Success in Offshore Information Technology (IT) Companies

    Science.gov (United States)

    Edara, Venkatarao

    2011-01-01

    Information technology (IT) projects are unsuccessful at a rate of 65% to 75% per year, in spite of employing the latest technologies and training employees. Although many studies have been conducted on project successes in U.S. companies, there is a lack of research studying the impact of various factors on software project success in offshore IT…

  5. Computer-to-plate Technology: Violet or Thermo?

    OpenAIRE

    Michael Mittelhaus

    2004-01-01

    Up to now CtP has been a technology for medium-sized and large companies and their printing presses, and thus predominantly in the 70 x 100 cm format and larger. The CtP technology is and remains divided up between violet and thermo, with the advantages and drawbacks of both imaging systems in a counterbalance. Due to the broad penetration of CtP in many markets, practical questions have now come to the fore, including those of continuous process control and quality assurance; providers and s...

  6. Soft city culture and technology the Betaville Project

    CERN Document Server

    Skelton, Carl

    2014-01-01

    Soft City Culture and Technology: The Betaville Project discusses the complete cycle of conception, development, and deployment of the Betaville platform. Betaville is a massively participatory online environment for distributed 3D design and development of proposals for changes to the built environment– an experimental integration of art, design, and software development for the public realm. Through a detailed account of Betaville from a Big Crazy Idea to a working "deep social medium", the author examines the current conditions of performance and accessibility of hardware, software, networks, and skills that can be brought together into a new form of open public design and deliberation space, for and spanning and integrating the disparate spheres of art, architecture, social media, and engineering. Betaville is an ambitious enterprise, of building compelling and constructive working relationships in situations where roles and disciplinary boundaries must be as agile as the development process of the soft...

  7. Proceedings of the nuclear criticality technology safety project

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, R.G. [comp.

    1997-06-01

    This document contains summaries of the most of the papers presented at the 1994 Nuclear Criticality Technology Safety Project (NCTSP) meeting, which was held May 10 and 11 at Williamsburg, Va. The meeting was broken up into seven sessions, which covered the following topics: (1) Validation and Application of Calculations; (2) Relevant Experiments for Criticality Safety; (3) Experimental Facilities and Capabilities; (4) Rad-Waste and Weapons Disassembly; (5) Criticality Safety Software and Development; (6) Criticality Safety Studies at Universities; and (7) Training. The minutes and list of participants of the Critical Experiment Needs Identification Workgroup meeting, which was held on May 9 at the same venue, has been included as an appendix. A second appendix contains the names and addresses of all NCTSP meeting participants. Separate abstracts have been indexed to the database for contributions to this proceedings.

  8. The JPL parabolic dish project. [solar collectors technology development

    Science.gov (United States)

    Truscello, V. C.; Williams, A. N.

    1980-01-01

    The parabolic dish solar collector is a highly versatile concentrating collector system that can produce heat for many thermal processes and electricity by coupling the collector to a suitable heat engine. This paper discusses a project for the development of these collector systems and summarizes contracts with industry for developing the dish subsystems which include concentrator, receiver, and heat engine. An early market for dishes is the dispersed small community market which depends heavily on oil to operate diesel or steam turbine plants in order to generate electricity. The present contracts with industry for conducting engineering experiments using the developed dish hardware to demonstrate the technology in these early opportunity markets is also discussed.

  9. Grandma's Games Project: Bridging Tradition and Technology Mediated Education

    Directory of Open Access Journals (Sweden)

    Marina Vasileva

    2014-02-01

    Full Text Available This article presents a project entitled "Grandma’s games", following a research idea to enrich the educational process of K9 students by introducing the traditional children games of our ancestors in the learning environment, revived and adapted for modern students with the aid of information and communication technology. While creating a strong connection between our heritage and the modern educational trends, the project’s intention goes beyond mere fulfilment of educational goals, striving to increase the interest and motivation of primary education students to develop their creativity and originality while learning, with respect of their own personal preferences and cultural heritage. The "Grandma’s games" research project engaged twelve traditional games in the educational activities at primary schools from both rural and non-rural environments in Republic of Macedonia. Descriptive statistics was applied on the data set sampled from the extensive survey conducted among teachers in these schools, to illustrate the benefits from the application of the Grandma’s games in educational process.

  10. ECUT (Energy Conversion and Utilization Technologies Program). Biocatalysis Project

    Science.gov (United States)

    1986-01-01

    Presented are the FY 1985 accomplishments, activities, and planned research efforts of the Biocatalysis Project of the U.S. Department of Energy, Energy Conversion and Utilization Technologies (ECUT) Program. The Project's technical activities were organized as follows: In the Molecular Modeling and Applied Genetics work element, research focused on (1) modeling and simulation studies to establish the physiological basis of high temperature tolerance in a selected enzyme and the catalytic mechanisms of three species of another enzyme, and (2) determining the degree of plasmid amplification and stability of several DNA bacterial strains. In the Bioprocess Engineering work element, research focused on (1) studies of plasmid propagation and the generation of models, (2) developing methods for preparing immobilized biocatalyst beads, and (3) developing an enzyme encapsulation method. In the Process Design and Analysis work element, research focused on (1) further refinement of a test case simulation of the economics and energy efficiency of alternative biocatalyzed production processes, (2) developing a candidate bioprocess to determine the potential for reduced energy consumption and facility/operating costs, and (3) a techno-economic assessment of potential advancements in microbial ammonia production.

  11. Review of PV Inverter Technology Cost and Performance Projections

    Energy Technology Data Exchange (ETDEWEB)

    Navigant Consulting Inc.

    2006-01-01

    The National Renewable Energy Laboratory (NREL) has a major responsibility in the implementation of the U.S. Department of Energy's (DOE's) Solar Energy Technologies Program. Sandia National Laboratories (SNL) has a major role in supporting inverter development, characterization, standards, certifications, and verifications. The Solar Energy Technologies Program recently published a Multiyear Technical Plan, which establishes a goal of reducing the Levelized Energy Cost (LEC) for photovoltaic (PV) systems to $0.06/kWh by 2020. The Multiyear Technical Plan estimates that, in order to meet the PV system goal, PV inverter prices will need to decline to $0.25-0.30 Wp by 2020. DOE determined the need to conduct a rigorous review of the PV Program's technical and economic targets, including the target set for PV inverters. NREL requested that Navigant Consulting Inc.(NCI) conduct a review of historical and projected cost and performance improvements for PV inverters, including identification of critical barriers identified and the approaches government might use to address them.

  12. Ceramic Technology Project. Semiannual progress report for April 1993 through September 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Ceramic Technology Project was originally developed by the Department of Energy`s Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS`s Materials Development Program, was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. During the course of the Ceramic Technology Project, remarkable progress has been made in the development of reliable structural ceramics. However, further work is needed to reduce the cost of ceramics to facilitate their commercial introduction, especially in the highly cost-sensitive automotive market. The work described in this report is organized according to the following WBS project elements: Project Management and Coordination; Materials and Processing; Materials Design Methodology; Data Base and Life Prediction; and Technology Transfer. This report includes contributions from all currently active project participants. Separate abstracts were prepared for the 47 projects reported here.

  13. Correlational Study of Risk Management and Information Technology Project Success

    Science.gov (United States)

    Gillespie, Seth J.

    2014-01-01

    Many IT projects fail despite the best efforts to keep these projects within budget, schedule, and scope. Few studies have looked at the effect of project risk management tools and techniques on project success. The primary focus of this study was to examine the extent to which utilization of project risk management processes influence project…

  14. Correlational Study of Risk Management and Information Technology Project Success

    Science.gov (United States)

    Gillespie, Seth J.

    2014-01-01

    Many IT projects fail despite the best efforts to keep these projects within budget, schedule, and scope. Few studies have looked at the effect of project risk management tools and techniques on project success. The primary focus of this study was to examine the extent to which utilization of project risk management processes influence project…

  15. A Synthesis and Survey of Critical Success Factors for Computer Technology Projects

    Science.gov (United States)

    Baker, Ross A.

    2012-01-01

    The author investigated the existence of critical success factors for computer technology projects. Current research literature and a survey of experienced project managers indicate that there are 23 critical success factors (CSFs) that correlate with project success. The survey gathered an assessment of project success and the degree to which…

  16. 78 FR 29335 - Science and Technology Reinvention Laboratory (STRL) Personnel Management Demonstration Projects

    Science.gov (United States)

    2013-05-20

    ... Management, AMRDEC, 5400 Fowler Road, Redstone Arsenal, AL 35898-5000; ERDC: Personnel Demonstration Project... of the Secretary Science and Technology Reinvention Laboratory (STRL) Personnel Management Demonstration Projects AGENCY: Office of the Deputy Assistant Secretary of Defense (Civilian Personnel...

  17. 78 FR 64204 - Science and Technology Reinvention Laboratory Personnel Management Demonstration Project...

    Science.gov (United States)

    2013-10-28

    ... published a notice of approval of a personnel management demonstration project for eligible ONR employees... of the Secretary Science and Technology Reinvention Laboratory Personnel Management Demonstration Project, Department of Navy, Office of Naval Research (ONR); Amendment and Corrections AGENCY:...

  18. Isolation of a euryhaline microalgal strain, Tetraselmis sp. CTP4, as a robust feedstock for biodiesel production

    Science.gov (United States)

    Pereira, Hugo; Gangadhar, Katkam N.; Schulze, Peter S. C.; Santos, Tamára; de Sousa, Carolina Bruno; Schueler, Lisa M.; Custódio, Luísa; Malcata, F. Xavier; Gouveia, Luísa; Varela, João C. S.; Barreira, Luísa

    2016-01-01

    Bioprospecting for novel microalgal strains is key to improving the feasibility of microalgae-derived biodiesel production. Tetraselmis sp. CTP4 (Chlorophyta, Chlorodendrophyceae) was isolated using fluorescence activated cell sorting (FACS) in order to screen novel lipid-rich microalgae. CTP4 is a robust, euryhaline strain able to grow in seawater growth medium as well as in non-sterile urban wastewater. Because of its large cell size (9–22 μm), CTP4 settles down after a six-hour sedimentation step. This leads to a medium removal efficiency of 80%, allowing a significant decrease of biomass dewatering costs. Using a two-stage system, a 3-fold increase in lipid content (up to 33% of DW) and a 2-fold enhancement in lipid productivity (up to 52.1 mg L−1 d−1) were observed upon exposure to nutrient depletion for 7 days. The biodiesel synthesized from the lipids of CTP4 contained high levels of oleic acid (25.67% of total fatty acids content) and minor amounts of polyunsaturated fatty acids with ≥4 double bonds (<1%). As a result, this biofuel complies with most of the European (EN14214) and American (ASTM D6751) specifications, which commonly used microalgal feedstocks are usually unable to meet. In conclusion, Tetraselmis sp. CTP4 displays promising features as feedstock with lower downstream processing costs for biomass dewatering and biodiesel refining. PMID:27767051

  19. Proposed Project Selection Method for Human Support Research and Technology Development (HSR&TD)

    Science.gov (United States)

    Jones, Harry

    2005-01-01

    The purpose of HSR&TD is to deliver human support technologies to the Exploration Systems Mission Directorate (ESMD) that will be selected for future missions. This requires identifying promising candidate technologies and advancing them in technology readiness until they are acceptable. HSR&TD must select an may of technology development projects, guide them, and either terminate or continue them, so as to maximize the resulting number of usable advanced human support technologies. This paper proposes an effective project scoring methodology to support managing the HSR&TD project portfolio. Researchers strongly disagree as to what are the best technology project selection methods, or even if there are any proven ones. Technology development is risky and outstanding achievements are rare and unpredictable. There is no simple formula for success. Organizations that are satisfied with their project selection approach typically use a mix of financial, strategic, and scoring methods in an open, established, explicit, formal process. This approach helps to build consensus and develop management insight. It encourages better project proposals by clarifying the desired project attributes. We propose a project scoring technique based on a method previously used in a federal laboratory and supported by recent research. Projects are ranked by their perceived relevance, risk, and return - a new 3 R's. Relevance is the degree to which the project objective supports the HSR&TD goal of developing usable advanced human support technologies. Risk is the estimated probability that the project will achieve its specific objective. Return is the reduction in mission life cycle cost obtained if the project is successful. If the project objective technology performs a new function with no current cost, its return is the estimated cash value of performing the new function. The proposed project selection scoring method includes definitions of the criteria, a project evaluation

  20. Thermal Protection System Materials (TPSM): Heat Shield for Extreme Entry Environment Technology (HEEET) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Heatshield for Extreme Entry Environ­ment Technology (HEEET) project seeks to mature a game changing Woven Ther­mal Protection System (TPS) technology to...

  1. Business planning innovative projects: the essence of technology, advantages and disadvantages

    Directory of Open Access Journals (Sweden)

    S.V. Knyaz

    2012-06-01

    Full Text Available The article substantiates the necessity to develop technology business planning innovative projects. Arguments made by the ground analysis of the advantages and disadvantages of existing business planning technologies.

  2. Green technology foresight of products and materials - some reflections and results from an ongoing Danish project

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Pedersen, Thomas Thoning; Falch, Morten

    2005-01-01

    The article presents some methodological and theoretical reflections and some preliminary results from a Danish Green Technology Foresight project about environmental friendly products and materials, where the environmental potentials and risks from three technology areas are analysed: nano- bio...

  3. Technology Performance Report: Duke Energy Notrees Wind Storage Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Wehner, Jeff [Duke Energy Renewables, Charlotte, NC (United States); Mohler, David [Duke Energy Renewables, Charlotte, NC (United States); Gibson, Stuart [Duke Energy Renewables, Charlotte, NC (United States); Clanin, Jason [Duke Energy Renewables, Charlotte, NC (United States); Faris, Don [Duke Energy Renewables, Charlotte, NC (United States); Hooker, Kevin [Duke Energy Renewables, Charlotte, NC (United States); Rowand, Michael [Duke Energy Renewables, Charlotte, NC (United States)

    2015-11-01

    Duke Energy Renewables owns and operates the Notrees Wind Farm in west Texas’s Ector and Winkler counties. The wind farm, which was commissioned in April 2009, has a total capacity of 152.6 MW generated by 55 Vestas V82 turbines, one Vestas 1-V90 experimental turbine, and 40 GE 1.5-MW turbines. The Vestas V82 turbines have a generating capacity of 1.65 MW each, the Vestas V90 turbine has a generating capacity of 1.86 MW, and the GE turbines have a generating capacity of 1.5 MW each. The objective of the Notrees Wind Storage Demonstration Project is to validate that energy storage increases the value and practical application of intermittent wind generation and is commercially viable at utility scale. The project incorporates both new and existing technologies and techniques to evaluate the performance and potential of wind energy storage. In addition, it could serve as a model for others to adopt and replicate. Wind power resources are expected to play a significant part in reducing greenhouse gas emissions from electric power generation by 2030. However, the large variability and intermittent nature of wind presents a barrier to integrating it within electric markets, particularly when competing against conventional generation that is more reliable. In addition, wind power production often peaks at night or other times when demand and electricity prices are lowest. Energy storage systems can overcome those barriers and enable wind to become a valuable asset and equal competitor to conventional fossil fuel generation.

  4. Projects to improve mathematics performance at a university of technology

    Directory of Open Access Journals (Sweden)

    Ina Louw

    2009-09-01

    Full Text Available Lecturers at tertiary institutions have been expressing concern about the quality of students in mathematics for a long time now. Blame is usually placed at the door of secondary schools, but through put figures are still determining state subsidies and as such necessitate institutions to constantly revisit their efforts in terms of improving performance in mathematics. In this article, the results of two studies to improve the mathematics performance at a technical university are reported. The first study took place at the former Technikon Northern Gauteng and was an action research project with an experimental design. The study entailed the implementation of tutorial sessions and it revealed certain traits of tertiary mathematics education. Data were collected through structured observation, questionnaires and focus group interviews. A standardized questionnaire, Study Orientation Questionnaire in Maths (SOM, was introduced and “study habits” was the field in the test that featured most significantly in both the experimental and the control groups. The results revealed, inter alia, that timely assessment is needed to detect and correct misconceptions as soon as possible. It also pointed out that attendance of lectures (and tutorials impacted strongly on performance. Lastly, it was found that students preferred communicating mathematics through the medium of English and not by using their mother tongue. The second project was conducted at the Tshwane University of Technology (TUT and consisted of an investigation into assessment practices in first year mathematics. The study was executed with action research as strategy and data were collected through interviews, questionnaires and focus group interviews. Qualitative and quantitative data were collected and respondents were exposed to contemporary assessment strategies as suggested by OBE. The aim of the study was to enhance the respondents’ insight into contemporary assessment

  5. A research of the quality of the dot copy in the CTP plate%CTP 版网点复制的质量研究

    Institute of Scientific and Technical Information of China (English)

    冷彩凤; 赵骁; 王兴

    2014-01-01

    In this article ,we use precise parameters to make the CTP plate .Then print the measure paper on 157 g/m2 duplex coated paper and 300 g/m2 gray background w hite card-board paer using exclusive imported offser printer R700 .With the help of magnifier and in-struments ,we can observe and record the changes through the dot copy .From these chan-ges ,the conclusion is that the definition and sharpness of dot are not ideal w hen making the CT P plate .But the dot can be exported linearly .And the spred of dot is greater ,the curve isn′t smooth .Also ,where the spread of dot is greatst has relationship to color .Showing the quality of dot reproduce ,this experiment is benificial to both tht development and application of CTP engraving .%选用精细制版参数制作C T P版,然后使用进口高档胶印机R700在157 g/m2双面铜版纸及300 g/m 2灰底白卡纸上印刷测控条,通过放大镜观察、仪器测试记录了网点复制过程的变化。从网点变化情况得知CTP版在制作时网点清晰度、锐利度不理想,但可以呈线性输出,而印刷过程中网点扩大偏大,且扩大曲线不够光滑,网点扩大最大处与色别有关。实验过程呈现出的网点复制质量对推动CTP版材的发展及应用提供了研究基础。

  6. Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1.

    Science.gov (United States)

    Zhu, Lin; Johnson, Christa; Bakovic, Marica

    2008-10-01

    Change in phosphoethanolamine pool size in tumor tissues is an important indicator of tumor prognosis and drug therapy efficacy. Phosphoethanolamine is the substrate of the regulatory enzyme CTP:phosphoethanolamine cytidylyltransferase (ECT) in the de novo biosynthesis of phosphatidylethanolamine (PE). Metabolic labeling with [14C]ethanolamine revealed a reduced ECT activity in MCF-7 breast cancer cells, which led to an accumulation of phosphoethanolamine and a decrease in PE synthesis in comparison with MCF-10A mammary epithelial cells. The enhanced ECT activity in MCF-10A cells was due to significantly elevated CTP:phosphoethanolamine cytidylyltransferase gene (PCYT2) expression, at the level of promoter activity, mRNA, and protein content. The early growth response protein 1 (EGR1) could account for most of the elevated ECT activity in MCF-10A cells relative to MCF-7 cells, as evidenced by promoter-luciferase reporter assays, gel-shift analyses, and by alterations in the EGR1 gene expression. In MCF-7 cells, EGR1 is present at lower levels and the basal PCYT2 promoter activity is maintained by proximal CAAT and GC regions and by elevated nuclear NFkappaB activity. Together, these data demonstrate that EGR1 is an important transcriptional stimulator of the human PCYT2 and that conditions that modify EGR1 also affect the function of ECT and consequently PE synthesis.

  7. Switching to biosimilar infliximab (CT-P13): Evidence of clinical safety, effectiveness and impact on public health.

    Science.gov (United States)

    Braun, Jürgen; Kudrin, Alex

    2016-07-01

    CT-P13, the biosimilar of infliximab, has been recently approved in the EU, Australia, Canada, Japan and many other countries. Thus, it was the first biosimilar approved in the field of rheumatology, dermatology and gastroenterology. Since there has been debate about the issue of switching from RMP to the biosimilar and some national societies have expressed concerns, this review was written with the following objectives: The review concludes that whilst prudent switching practices should be employed, growing safety experience accumulated thus far with CT-P13 and other biosimilars is favorable and does not raise any specific concerns.

  8. Projects in Technology Education and Fostering Learning: The Potential and Its Realization

    Science.gov (United States)

    Barak, Moshe; Shachar, Ahron

    2008-06-01

    The current study aimed at examining the efficacy of technological projects as learning tools by exploring the following questions: the extent to which projects in technology develop students as independent learners; the types of knowledge the students deal with in working on their projects; the role of problem-solving in technological projects; and how projects integrate into traditional schooling. The subjects were 53 high school (12th grade) students who prepared graduating projects in technology under the supervision of nine teachers. Data were collected by observing the students in the laboratory, administrating two questionnaires to both the students and the teachers, and analyzing 25 portfolios prepared by the students of their projects. The findings indicate that projects in technology provide a good opportunity to engage students in challenging tasks that enhance their learning skills. To maximize this potential, it is necessary to employ the project method from the early stages of learning technology. It is especially important that teachers having a strong engineering orientation also acquire pedagogical knowledge on issues such as fostering independent learning, creativity, peer learning and reflective practice in the technological classroom.

  9. Teaching Engineering Statistics with Technology, Group Learning, Contextual Projects, Simulation Models and Student Presentations

    Science.gov (United States)

    Romeu, Jorge Luis

    2008-01-01

    This article discusses our teaching approach in graduate level Engineering Statistics. It is based on the use of modern technology, learning groups, contextual projects, simulation models, and statistical and simulation software to entice student motivation. The use of technology to facilitate group projects and presentations, and to generate,…

  10. The AECT HistoryMakers Project: Conversations with Leaders in Educational Technology

    Science.gov (United States)

    Lockee, Barbara B.; Song, Kibong; Li, Wei

    2014-01-01

    The early beginnings and evolution of the field of educational technology (ET) have been documented by various scholars in the field. Recently, another form of historical documentation has been undertaken through a project of the Association for Educational Communications and Technology (AECT). The AECT HistoryMakers Project is a collaborative…

  11. Teaching Engineering Statistics with Technology, Group Learning, Contextual Projects, Simulation Models and Student Presentations

    Science.gov (United States)

    Romeu, Jorge Luis

    2008-01-01

    This article discusses our teaching approach in graduate level Engineering Statistics. It is based on the use of modern technology, learning groups, contextual projects, simulation models, and statistical and simulation software to entice student motivation. The use of technology to facilitate group projects and presentations, and to generate,…

  12. An Examination of the Determinants of Top Management Support of Information Technology Projects

    Science.gov (United States)

    Mahoney, Michael L.

    2011-01-01

    Despite compelling evidence that top management support promotes information technology project success, existing research fails to offer insight into the antecedents of top management support of such projects. This gap in the literature is significant since the exploitation of information technology offers organizations unique opportunities for…

  13. Financing Projects That Use Clean-Energy Technologies. An Overview of Barriers and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Goldman, D. P. [New Energy Capital, LLC, Hanover, NH (United States); McKenna, J. J. [Hamilton Clark & Co., Washington, DC (United States); Murphy, L. M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2005-10-01

    This technical paper describes the importance of project financing for clean-energy technology deployment. It describes the key challenges in financing clean-energy technology projects, including technical risks, credit worthiness risk, revenue security risk, market competition, scale and related cost, as well as first-steps to overcome those barriers.

  14. Including information technology project management in the nursing informatics curriculum.

    Science.gov (United States)

    Sockolow, Paulina; Bowles, Kathryn H

    2008-01-01

    Project management is a critical skill for nurse informaticists who are in prominent roles developing and implementing clinical information systems. It should be included in the nursing informatics curriculum, as evidenced by its inclusion in informatics competencies and surveys of important skills for informaticists. The University of Pennsylvania School of Nursing includes project management in two of the four courses in the master's level informatics minor. Course content includes the phases of the project management process; the iterative unified process methodology; and related systems analysis and project management skills. During the introductory course, students learn about the project plan, requirements development, project feasibility, and executive summary documents. In the capstone course, students apply the system development life cycle and project management skills during precepted informatics projects. During this in situ experience, students learn, the preceptors benefit, and the institution better prepares its students for the real world.

  15. Geothermal Reservoir Technology Research Program: Abstracts of selected research projects

    Energy Technology Data Exchange (ETDEWEB)

    Reed, M.J. (ed.)

    1993-03-01

    Research projects are described in the following areas: geothermal exploration, mapping reservoir properties and reservoir monitoring, and well testing, simulation, and predicting reservoir performance. The objectives, technical approach, and project status of each project are presented. The background, research results, and future plans for each project are discussed. The names, addresses, and telephone and telefax numbers are given for the DOE program manager and the principal investigators. (MHR)

  16. New technologies for DNA analysis – a review of the READNA Project

    NARCIS (Netherlands)

    McGinn, Steven; Bauer, David; Brefort, Thomas; Dong, Liqin; El-Sagheer, Afaf; Elsharawy, Abdou; Evans, Geraint; Falk-Sörqvist, Elin; Forster, Michael; Fredriksson, Simon; Freeman, Peter; Freitag, Camilla; Fritzsche, Joachim; Gibson, Spencer; Gullberg, Mats; Gut, Marta; Heath, Simon; Heath-Brun, Isabelle; Heron, Andrew J.; Hohlbein, Johannes; Ke, Rongqin; Lancaster, Owen; Reste, Le Ludovic; Maglia, Giovanni; Marie, Rodolphe; Mauger, Florence; Mertes, Florian; Mignardi, Marco; Moens, Lotte; Oostmeijer, Jelle; Out, Ruud; Pedersen, Jonas Nyvold; Persson, Fredrik; Picaud, Vincent; Rotem, Dvir; Schracke, Nadine; Sengenes, Jennifer; Stähler, Peer F.; Stade, Björn; Stoddart, David; Teng, Xia; Veal, Colin D.; Zahra, Nathalie; Bayley, Hagan; Beier, Markus; Brown, Tom; Dekker, Cees; Ekström, Björn; Flyvbjerg, Henrik; Franke, Andre; Guenther, Simone; Kapanidis, Achillefs N.; Kaye, Jane; Kristensen, Anders; Lehrach, Hans; Mangion, Jonathan; Sauer, Sascha; Schyns, Emile; Tost, Jörg; Helvoort, van Joop M.L.M.; Zaag, van der Pieter J.; Tegenfeldt, Jonas O.; Brookes, Anthony J.; Mir, Kalim; Nilsson, Mats; Willcocks, James P.; Gut, Ivo G.

    2016-01-01

    The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and deve

  17. New Technologies for DNA analysis-A review of the READNA Project

    NARCIS (Netherlands)

    McGinn, Steven; Bauer, David; Brefort, Thomas; Dong, Liqin; El-Sagheer, Afaf; Elsharawy, Abdou; Evans, Geraint; Falk-Sörqvist, Elin; Forster, Michael; Fredriksson, Simon; Freeman, Peter; Freitag, Camilla; Fritzsche, Joachim; Gibson, Spencer; Gullberg, Mats; Gut, Marta; Heath, Simon; Heath-Brun, Isabelle; Heron, Andrew J; Hohlbein, Johannes; Ke, Rongqin; Lancaster, Owen; Le Reste, Ludovic; Maglia, Giovanni; Marie, Rodolphe; Mauger, Florence; Mertes, Florian; Mignardi, Marco; Moens, Lotte; Oostmeijer, Jelle; Out, Ruud; Pedersen, Jonas Nyvold; Persson, Fredrik; Picaud, Vincent; Rotem, Dvir; Schracke, Nadine; Sengenes, Jennifer; Stähler, Peer F; Stade, Björn; Stoddart, David; Teng, Xia; Veal, Colin D; Zahra, Nathalie; Bayley, Hagan; Beier, Markus; Brown, Tom; Dekker, Cees; Ekström, Björn; Flyvbjerg, Henrik; Franke, Andre; Guenther, Simone; Kapanidis, Achillefs N; Kaye, Jane; Kristensen, Anders; Lehrach, Hans; Mangion, Jonathan; Sauer, Sascha; Schyns, Emile; Tost, Jörg; van Helvoort, Joop M L M; van der Zaag, Pieter J; Tegenfeldt, Jonas O; Brookes, Anthony J; Mir, Kalim; Nilsson, Mats; Willcocks, Spike; Gut, Ivo G

    2016-01-01

    The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and deve

  18. Technological and regulatory aspects of quality management during the life cycle of investment and construction projects

    OpenAIRE

    Kropyvko Serhii Maksymovych

    2016-01-01

    The division of the life cycle of investment and construction projects in four phases, based on their technological features, is proposed in the article. Regulatory aspects of quality management during each phase of the life cycle of investment and construction projects are analyzed. The model of quality management during the phases of the life cycle of investment and construction project is developed.

  19. Success Rates by Software Development Methodology in Information Technology Project Management: A Quantitative Analysis

    Science.gov (United States)

    Wright, Gerald P.

    2013-01-01

    Despite over half a century of Project Management research, project success rates are still too low. Organizations spend a tremendous amount of valuable resources on Information Technology projects and seek to maximize the utility gained from their efforts. The author investigated the impact of software development methodology choice on ten…

  20. The Effects of the Project Champion's Leadership Style on Global Information Technology User Acceptance and Use

    Science.gov (United States)

    Ekiko, Mbong C.

    2014-01-01

    The research problem was the lack of knowledge about the effect of leadership style of the project champion on global information technology (IT) project outcomes, resulting in a high failure rate of IT projects accompanied by significant waste of resources. The purpose of this quantitative, nonexperimental study was to evaluate the relationship…

  1. Harnessing the Power of Technologies to Manage Collaborative e-Learning Projects in Dispersed Environments

    Science.gov (United States)

    Gosper, Maree Veroncia; McNeill, Margot Anne; Woo, Karen

    2010-01-01

    "The impact of web-based lecture technologies on current and future practice in learning and teaching" was a collaborative project across four Australian universities, funded by the Australian Learning and Teaching Council (ALTC). The project was both exploratory and developmental in nature and according to the project's external…

  2. New Technologies for DNA analysis-A review of the READNA Project

    NARCIS (Netherlands)

    McGinn, Steven; Bauer, David; Brefort, Thomas; Dong, Liqin; El-Sagheer, Afaf; Elsharawy, Abdou; Evans, Geraint; Falk-Sörqvist, Elin; Forster, Michael; Fredriksson, Simon; Freeman, Peter; Freitag, Camilla; Fritzsche, Joachim; Gibson, Spencer; Gullberg, Mats; Gut, Marta; Heath, Simon; Heath-Brun, Isabelle; Heron, Andrew J; Hohlbein, Johannes; Ke, Rongqin; Lancaster, Owen; Le Reste, Ludovic; Maglia, Giovanni; Marie, Rodolphe; Mauger, Florence; Mertes, Florian; Mignardi, Marco; Moens, Lotte; Oostmeijer, Jelle; Out, Ruud; Pedersen, Jonas Nyvold; Persson, Fredrik; Picaud, Vincent; Rotem, Dvir; Schracke, Nadine; Sengenes, Jennifer; Stähler, Peer F; Stade, Björn; Stoddart, David; Teng, Xia; Veal, Colin D; Zahra, Nathalie; Bayley, Hagan; Beier, Markus; Brown, Tom; Dekker, Cees; Ekström, Björn; Flyvbjerg, Henrik; Franke, Andre; Guenther, Simone; Kapanidis, Achillefs N; Kaye, Jane; Kristensen, Anders; Lehrach, Hans; Mangion, Jonathan; Sauer, Sascha; Schyns, Emile; Tost, Jörg; van Helvoort, Joop M L M; van der Zaag, Pieter J; Tegenfeldt, Jonas O; Brookes, Anthony J; Mir, Kalim; Nilsson, Mats; Willcocks, Spike; Gut, Ivo G

    2016-01-01

    The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and deve

  3. New technologies for DNA analysis – a review of the READNA Project

    NARCIS (Netherlands)

    McGinn, Steven; Bauer, David; Brefort, Thomas; Dong, Liqin; El-Sagheer, Afaf; Elsharawy, Abdou; Evans, Geraint; Falk-Sörqvist, Elin; Forster, Michael; Fredriksson, Simon; Freeman, Peter; Freitag, Camilla; Fritzsche, Joachim; Gibson, Spencer; Gullberg, Mats; Gut, Marta; Heath, Simon; Heath-Brun, Isabelle; Heron, Andrew J.; Hohlbein, Johannes; Ke, Rongqin; Lancaster, Owen; Reste, Le Ludovic; Maglia, Giovanni; Marie, Rodolphe; Mauger, Florence; Mertes, Florian; Mignardi, Marco; Moens, Lotte; Oostmeijer, Jelle; Out, Ruud; Pedersen, Jonas Nyvold; Persson, Fredrik; Picaud, Vincent; Rotem, Dvir; Schracke, Nadine; Sengenes, Jennifer; Stähler, Peer F.; Stade, Björn; Stoddart, David; Teng, Xia; Veal, Colin D.; Zahra, Nathalie; Bayley, Hagan; Beier, Markus; Brown, Tom; Dekker, Cees; Ekström, Björn; Flyvbjerg, Henrik; Franke, Andre; Guenther, Simone; Kapanidis, Achillefs N.; Kaye, Jane; Kristensen, Anders; Lehrach, Hans; Mangion, Jonathan; Sauer, Sascha; Schyns, Emile; Tost, Jörg; Helvoort, van Joop M.L.M.; Zaag, van der Pieter J.; Tegenfeldt, Jonas O.; Brookes, Anthony J.; Mir, Kalim; Nilsson, Mats; Willcocks, James P.; Gut, Ivo G.

    2016-01-01

    The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and deve

  4. Success Rates by Software Development Methodology in Information Technology Project Management: A Quantitative Analysis

    Science.gov (United States)

    Wright, Gerald P.

    2013-01-01

    Despite over half a century of Project Management research, project success rates are still too low. Organizations spend a tremendous amount of valuable resources on Information Technology projects and seek to maximize the utility gained from their efforts. The author investigated the impact of software development methodology choice on ten…

  5. New business opportunity: Green field project with new technology

    Directory of Open Access Journals (Sweden)

    Lee Seung Jae

    2014-06-01

    Full Text Available Since 2009 of global financial crisis, shipbuilding industry has undergone hard times seriously. After such a long depression, the latest global shipping market index shows that the economic recovery of global shipbuilding market is underway. Especially, nations with enormous resources are going to increase their productivity or expanding their shipyards to accommodate a large amount of orders expected in the near future. However, few commercial projects have been carried out for the practical shipyard layout designs even though those can be good commercial opportunities for shipbuilding engineers. Shipbuilding starts with a shipyard construction with a large scale investment initially. Shipyard design and the equipment layout problem, which is directly linked to the productivity of ship production, is an important issue in the production planning of mass production of ships. In many cases, shipbuilding yard design has relied on the experience of the internal engineer, resulting in sporadic and poorly organized processes. Consequently, economic losses and the trial and error involved in such a design process are inevitable problems. The starting point of shipyard construction is to design a shipyard layout. Four kinds of engineering parts required for the shipyard layout design and construction. Those are civil engineering, building engineering, utility engineering and production layout engineering. Among these parts, production layout engineering is most important because its result is used as a foundation of the other engineering parts, and also, determines the shipyard capacity in the shipyard lifecycle. In this paper, the background of shipbuilding industry is explained in terms of engineering works for the recognition of the macro trend. Nextly, preliminary design methods and related case study is introduced briefly by referencing the previous research. Lastly, the designed work of layout design is validated using the computer simulation

  6. New business opportunity: Green field project with new technology

    Science.gov (United States)

    Lee, Seung Jae; Woo, Jong Hun; Shin, Jong Gye

    2014-06-01

    Since 2009 of global financial crisis, shipbuilding industry has undergone hard times seriously. After such a long depression, the latest global shipping market index shows that the economic recovery of global shipbuilding market is underway. Especially, nations with enormous resources are going to increase their productivity or expanding their shipyards to accommodate a large amount of orders expected in the near future. However, few commercial projects have been carried out for the practical shipyard layout designs even though those can be good commercial opportunities for shipbuilding engineers. Shipbuilding starts with a shipyard construction with a large scale investment initially. Shipyard design and the equipment layout problem, which is directly linked to the productivity of ship production, is an important issue in the production planning of mass production of ships. In many cases, shipbuilding yard design has relied on the experience of the internal engineer, resulting in sporadic and poorly organized processes. Consequently, economic losses and the trial and error involved in such a design process are inevitable problems. The starting point of shipyard construction is to design a shipyard layout. Four kinds of engineering parts required for the shipyard layout design and construction. Those are civil engineering, building engineering, utility engineering and production layout engineering. Among these parts, production layout engineering is most important because its result is used as a foundation of the other engineering parts, and also, determines the shipyard capacity in the shipyard lifecycle. In this paper, the background of shipbuilding industry is explained in terms of engineering works for the recognition of the macro trend. Nextly, preliminary design methods and related case study is introduced briefly by referencing the previous research. Lastly, the designed work of layout design is validated using the computer simulation technology.

  7. Keynote presentation: Project Management, Technology and Evolving Work Processes

    DEFF Research Database (Denmark)

    Kampf, Constance Elizabeth

    Bridging the classroom and workplace is a challenge in the Project Management classroom because students rarely have the opportunity or the experience needed to head up large projects. So how can instructors present the opportunity to develop skills and gain experience needed to understand project...... management in a classroom setting? To begin to answer this question, the presentation describes three key strategies used in a Project Management course developed from a communications perspective in the International Bachelor Program in Marketing and Management Communication, Business & Social Sciences......, Aarhus University. First, this Project Management course involves continual, ongoing development through working with real clients. To learn about project management from a communications perspective, learners were asked to work in teams for project conception and planning. To communicate with the client...

  8. Novel High Pressure Pump-on-a-Chip Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology, Inc proposes to develop a novel high pressure "pump-on-a-chip" and "valve-on-a-chip" microfluidic technology for NASA planetary science...

  9. Enabling Technologies for Fabrication of Large Area Flexible Antennas Project

    Data.gov (United States)

    National Aeronautics and Space Administration — MesoScribe Technologies, a high tech start-up from SUNY-Stony Brook, proposes to apply a breakthrough new direct writing technology to meet the objectives set-forth...

  10. Novel High Pressure Pump-on-a-Chip Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology, Inc. proposes to develop a novel high pressure "pump-on-a-chip" (HPPOC) technology capable of generating high pressure and flow rate on...

  11. Technological Innovation Projects: Proposal For an Integrative Model Between Project Management and Knowledge Management in a Customer-Supplier Perspective

    Directory of Open Access Journals (Sweden)

    Edval da Silva Tavares

    2014-10-01

    Full Text Available In face of strong competition, companies in Brazil have increased their financial investments in automation, offering new products and services and reducing operating costs. These companies are focusing their efforts on core competencies and, therefore, they often lack the internal expertise to implement new projects, especially those that bring technological innovation. For this reason, we use the processes of outsourcing or subcontracting to help implement such projects. The unit of analysis in this study is the project and the object of the study to analyze the process of knowledge transfer from a provider to a customer during the duration of the project, which involves new technologies. The main motivation of this work is to address the acquisition and retention of new knowledge related to projects designed for business customers. We have developed a study of three cases of multiple financial firms that buy new technologies and two suppliers of information technology. As a practical result, a management model of knowledge transfer and retention of knowledge in client companies is proposed and incorporated into project management.

  12. The Carnegie H.A.T. Project--History and Technology.

    Science.gov (United States)

    Laskey, Sue

    1991-01-01

    Describes the History and Technology Project (HAT) at a model technology school. Offers suggestions of suitable hardware and software, and ideas for funding. Emphasizes the goal of integrating technology into all levels of history and social science. Calls for increasing teacher-student interaction and restructuring teaching methods to reach all…

  13. How Undergraduate Students Use Social Media Technologies to Support Group Project Work

    Science.gov (United States)

    McAliney, Peter J.

    2013-01-01

    Technology continues to evolve and become accessible to students in higher education. Concurrently, teamwork has become an important skill in academia and the workplace and students have adopted established technologies to support their learning in both individual and team project work. Given the emergence of social media technologies, I examined…

  14. How Undergraduate Students Use Social Media Technologies to Support Group Project Work

    Science.gov (United States)

    McAliney, Peter J.

    2013-01-01

    Technology continues to evolve and become accessible to students in higher education. Concurrently, teamwork has become an important skill in academia and the workplace and students have adopted established technologies to support their learning in both individual and team project work. Given the emergence of social media technologies, I examined…

  15. Next Slide Please: The Magical, Scientific and Corporate Discourses of Visual Projection Technologies

    Science.gov (United States)

    Eisenhauer, Jennifer F.

    2006-01-01

    This article examines the cultural history of slide projection technologies by focusing upon how such technologies acquire cultural meaning. The meanings acquired by these technologies emerge in areas as diverse as public and domestic entertainment, religion, science, and education. I identify three important discursive shifts impacting the…

  16. Factors influencing the societal acceptance of new energy technologies. Meta-analysis of recent European projects

    Energy Technology Data Exchange (ETDEWEB)

    Poti, B.; Difiore, M. [Consiglio Nazionale delle Ricerche, Rome (Italy); Brohmann, B.; Daniels, A.; Fritsche, U.; Huenecke, K. [Oeko-Institut, Darmstadt (Germany); Heiskanen, E. [National Consumer Research Centre, Helsinki (Finland); Raven, R.P.J.M.; Mourik, R.; Feenstra, C.F.J.; Willemse, R. [ECN Policy Studies, Petten (Netherlands); Hodson, M. [Centre for Sustainable Urban and Regional Futures SURF, University of Salford, Manchester (United Kingdom); Alcantud Torrent, A.; Schaefer, B. [Ecoinstitut Barcelona, Barcelona (Spain); Farkas, B.; Fucsko, J. [Hungarian Environmental Economics Centre MAKK, Budapest (Hungary); Jolivet, E. [IAE Toulouse, Toulouse (France); Maack, M.H.; Matschoss, K. [Icelandic New Energy INE, Reykjavik (Iceland); Oniszk-Poplawska, A. [Institute for Renewable Energy IEO, Warszawa (Poland); Prasad, G. [Energy Research Centre ERC, University of Cape Town, Cape Town (South Africa)

    2008-03-15

    Within this report an analysis is made of 27 case studies of historical and recent new energy technologies in different European regions and South Africa. The analysis focuses on the societal acceptance in these projects in order to identify determinants of success and failure. A wide diversity of technologies is discussed including hydrogen, CO2 capture and storage, biomass, solar and wind energy technologies.

  17. Characterizing topological bottlenecks for data delivery in CTP using simulation-based stress testing with natural selection

    NARCIS (Netherlands)

    Bucur, Doina; Iacca, Giovanni; Boer, de Pieter-Tjerk

    2015-01-01

    Routing protocols for ad-hoc networks, e.g., the Collection Tree Protocol (CTP), are designed with simple node-local behaviour, but are deployed on testbeds with uncontrollable physical topology; exhaustively verifying the protocol on all possible topologies at design time is not tractable. We obtai

  18. Clinical monitoring: infliximab biosimilar CT-P13 in the treatment of Crohn’s disease and ulcerative colitis

    Science.gov (United States)

    Keil, Radan; Wasserbauer, Martin; Zádorová, Zdena; Hajer, Jan; Drastich, Pavel; Wohl, Pavel; Beneš, Marek; Bojková, Martina; Svoboda, Pavel; Konečný, Michal; Falt, Přemysl; Vaňásek, Tomáš; Pešta, Martin; Pešek, František; Bouchner, Luděk; Koželuhová, Jana; Novotný, Aleš; Bartůsková, Lucie; Špičák, Julius

    2016-01-01

    Abstract Objective: The infliximab biosimilar CT-P13 (Remsima®, Inflectra®) was approved in Europe for the treatment of inflammatory bowel disease (IBD) based on extrapolation of data from patients with rheumatic disease. Because there are limited published reports on clinical outcomes for IBD patients treated with CT-P13, we monitored responses to induction treatment with this biosimilar in patients with Crohn’s disease (CD) or ulcerative colitis (UC) in centres across the Czech Republic. Material and methods: Fifty-two patients with CD (n = 30) or UC (n = 22) were treated with 5 mg/kg CT-P13 for up to 14 weeks. Effectiveness of therapy was evaluated with the Crohn’s Disease Activity Index (CDAI) or the Mayo Scoring System (MSS) in patients with CD or UC, respectively, before and after 14 weeks. Additional goals were to evaluate weight changes, serum C-reactive protein (CRP) levels, and complications/adverse events. Results: In patients with CD, remission (CDAI herpes labialis, pneumonia and allergic reaction. Conclusions: This prospective observational study provides evidence of the effectiveness of CT-P13 in IBD. PMID:27002981

  19. Dose reduction in orthodontic lateral cephalography: dosimetric evaluation of a novel cephalographic thyroid protector (CTP) and anatomical cranial collimation (ACC)

    NARCIS (Netherlands)

    Hoogeveen, R.C.; Rottke, D.; van der Stelt, P.F.; Berkhout, W.E.R.

    2015-01-01

    Objectives: To test the dose-reducing capabilities of a novel thyroid protection device and a recently introduced cranial collimator to be used in orthodontic lateral cephalography. Methods: Cephalographic thyroid protector (CTP) was designed to shield the thyroid while leaving the cervical vertebra

  20. Using Project Portfolio Management in a Junior Enterprise Technology

    Directory of Open Access Journals (Sweden)

    RIBEIRO, D. M.

    2011-06-01

    Full Text Available Junior Enterprises have their own particularities in managing of their projects. Scarcity of resources and lack of experience of its members are critics and typical factors in the daily life of these companies. However, these and other variables such as the time for return on investment, project complexity and runtime of the project, must be taken into consideration in the prioritization of the outstanding portfolio projects to maximize desired outcomes. The Portfolio Management aims to provide the company a better allocation of resources in an environment with multiple projects going simultaneously. The model proposed here seeks a link between projects and organizational strategy. In this Paper also are presented the results of applying the model on Upe consultoria JR.

  1. Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2

    Directory of Open Access Journals (Sweden)

    Lin Zhu

    2008-01-01

    Full Text Available Metabolic pulse-chase experiments demonstrated that 25-hydroxycholesterol (25-OH, the endogenous activator of the liver X receptor (LXR, significantly reduced the biosynthesis of phosphatidylethanolamine via CDP-ethanolamine (Kennedy pathway at the step catalyzed by CTP: phosphoethanolamine cytidylyltransferase (Pcyt2. In the mouse embryonic fibroblasts C3H10T1/2, the LXR synthetic agonist TO901317 lowered Pcyt2 promoter-luciferase activity in a concentration-dependent manner. Furthermore, 25-OH and TO901317 reduced mouse Pcyt2 mRNA and protein levels by 35–60%. The inhibitory effects of oxysterols and TO901317 on the Pcyt2 promoter function, mRNA and protein expression were conserved in the human breast cancer cells MCF-7. These studies identify the Pcyt2 gene as a novel target whereby LXR agonists may indirectly modulate inflammatory responses and atherosclerosis.

  2. Conformation of nanoconfined DNA as a function of ATP, AMP, CTP, Mg2+, and dye binding

    Science.gov (United States)

    Roushan, Maedeh; Riehn, Robert

    2014-03-01

    DNA molecules stretch in nanochannels with a channel cross-section of 100x100 nm2, thereby allowing analysis by observation of a fluorescent dye. The length and configuration of DNA can be directly observed, and the effect of different DNA-binding proteins on DNA configuration can be studied. Recently, we reported on the ability of T4 ligase to transiently manipulate DNA as a function of ATP and magnesium exposure. In this process we have extensively probed the interactions of dyes and enzyme co-factors with DNA under nanoconfinement. We find negligible effects if DNA is visualized using groove-binding dyes such as DAPI. However, if an intercalating dye (YOYO-1) is used, we find a significant shortening of the DNA in the presence of ATP that we attribute to an interaction of dye and ATP (as well as AMP and CTP). We did not record a noticeable effect due to Mg2+.

  3. Technology projects for characterization--monitoring of volatile organic compounds (VOCs)

    Energy Technology Data Exchange (ETDEWEB)

    Junk, G.A.; Haas, W.J. Jr.

    1992-07-01

    One hundred thirty technology project titles related to the characterization of volatile organic compounds (VOCs) at an arid site are listed alphabetically by first contact person in a master compilation that includes phone numbers, addresses, keywords, and short descriptions. Separate tables are presented for 62 field-demonstrated, 36 laboratory-demonstrated, and 35 developing technology projects. The technology projects in each of these three categories are also prioritized in separate summary tables. Additional tables are presented for a number of other categorizations of the technology projects: In Situ; Fiberoptic; Mass Spectrometer; Optical Spectroscopy; Raman or SERS; Ion Mobility or Acoustic; Associated; and Commercial. Four lists of contact person names are provided so details concerning the projects that deal with sampling, and VOCs in gases, waters, and soils (sediments) can be obtained. Finally, seven wide-ranging conclusions based on observations and experiences during this work are presented.

  4. Northwest Open Automated Demand Response Technology Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccote, Sila; Dudley, Junqiao Han; Piette, Mary Ann

    2009-08-01

    Lawrence Berkeley National Laboratory (LBNL) and the Demand Response Research Center (DRRC) performed a technology demonstration and evaluation for Bonneville Power Administration (BPA) in Seattle City Light's (SCL) service territory. This report summarizes the process and results of deploying open automated demand response (OpenADR) in Seattle area with winter morning peaking commercial buildings. The field tests were designed to evaluate the feasibility of deploying fully automated demand response (DR) in four to six sites in the winter and the savings from various building systems. The project started in November of 2008 and lasted 6 months. The methodology for the study included site recruitment, control strategy development, automation system deployment and enhancements, and evaluation of sites participation in DR test events. LBNL subcontracted McKinstry and Akuacom for this project. McKinstry assisted with recruitment, site survey collection, strategy development and overall participant and control vendor management. Akuacom established a new server and enhanced its operations to allow for scheduling winter morning day-of and day-ahead events. Each site signed a Memorandum of Agreement with SCL. SCL offered each site $3,000 for agreeing to participate in the study and an additional $1,000 for each event they participated. Each facility and their control vendor worked with LBNL and McKinstry to select and implement control strategies for DR and developed their automation based on the existing Internet connectivity and building control system. Once the DR strategies were programmed, McKinstry commissioned them before actual test events. McKinstry worked with LBNL to identify control points that can be archived at each facility. For each site LBNL collected meter data and trend logs from the energy management and control system. The communication system allowed the sites to receive day-ahead as well as day-of DR test event signals. Measurement of DR was

  5. A disruption of ctpA encoding carboxy-terminal protease attenuates Burkholderia mallei and induces partial protection in CD1 mice.

    Science.gov (United States)

    Bandara, Aloka B; DeShazer, David; Inzana, Thomas J; Sriranganathan, Nammalwar; Schurig, Gerhardt G; Boyle, Stephen M

    2008-09-01

    Burkholderia mallei is the etiologic agent of glanders in solipeds (horses, mules and donkeys), and incidentally in carnivores and humans. Little is known about the molecular mechanisms of B. mallei pathogenesis. The putative carboxy-terminal processing protease (CtpA) of B. mallei is a member of a novel family of endoproteases involved in the maturation of proteins destined for the cell envelope. All species and isolates of Burkholderia carry a highly conserved copy of ctpA. We studied the involvement of CtpA on growth, cell morphology, persistence, and pathogenicity of B. mallei. A sucrose-resistant strain of B. mallei was constructed by deleting a major portion of the sacB gene of the wild type strain ATCC 23344 by gene replacement, and designated as strain 23344DeltasacB. A portion of the ctpA gene (encoding CtpA) of strain 23344DeltasacB was deleted by gene replacement to generate strain 23344DeltasacBDeltactpA. In contrast to the wild type ATCC 23344 or the sacB mutant 23344DeltasacB, the ctpA mutant 23344DeltasacBDeltactpA displayed altered cell morphologies with partially or fully disintegrated cell envelopes. Furthermore, relative to the wild type, the ctpA mutant displayed slower growth in vitro and less ability to survive in J774.2 murine macrophages. The expression of mRNA of adtA, the gene downstream of ctpA was similar among the three strains suggesting that disruption of ctpA did not induce any polar effects. As with the wild type or the sacB mutant, the ctpA mutant exhibited a dose-dependent lethality when inoculated intraperitoneally into CD1 mice. The CD1 mice inoculated with a non-lethal dose of the ctpA mutant produced specific serum immunoglobulins IgG1 and IgG2a and were partially protected against challenge with wild type B. mallei ATCC 23344. These findings suggest that CtpA regulates in vitro growth, cell morphology and intracellular survival of B. mallei, and a ctpA mutant protects CD1 mice against glanders.

  6. A Proposal to Manage Lessons Learned in Projects: Web 2.0 Technologies to Promote Innovation

    Directory of Open Access Journals (Sweden)

    Marcirio Silveira Chaves

    2014-06-01

    Full Text Available The web 2.0 is transforming the project management in organizations by improving communication and collaboration. The new generation of web-based collaborative tools provides much better experience than the traditional software package allowing document sharing, integrated task tracking, enforcing team processes and agile planning. Despite of the indubitable benefits brought by web 2.0, the use of these technologies to promote knowledge management remains unexplored. For many project managers to obtain and integrate information from different tools of previous similar projects in global organizations remains a challenge. This theoretical paper presents a proposal that suggests an innovation in the knowledge management area applying web 2.0 technologies. The main goal is to provide an integrated vision of a set of technologies that could be used by organizations in order to promote better management of lessons learned. The proposal includes the lessons learned processes (e.g. capture, share and dissemination, the process-based (e.g. project review and after action review and documentation-based (e.g. micro article and learning histories methods. Results show how web 2.0 technologies can help project managers and team project to cope with the main lessons learned processes and methods to learn from experience. Moreover, recommendations are made for the effective use of web 2.0 components promoting innovation and supporting lessons learned management in projects.Keywords: Project management; Lessons learned processes; lessons learned methods; project learning; web 2.0 technologies; innovation.

  7. Los Alamos National Laboratory Tritium Technology Deployments Large Scale Demonstration and Deployment Project

    Energy Technology Data Exchange (ETDEWEB)

    McFee, J.; Blauvelt, D.; Stallings, E.; Willms, S.

    2002-02-26

    This paper describes the organization, planning and initial implementation of a DOE OST program to deploy proven, cost effective technologies into D&D programs throughout the complex. The primary intent is to accelerate closure of the projects thereby saving considerable funds and at the same time being protective of worker health and the environment. Most of the technologies in the ''toolkit'' for this program have been demonstrated at a DOE site as part of a Large Scale Demonstration and Deployment Project (LSDDP). The Mound Tritium D&D LSDDP served as the base program for the technologies being deployed in this project but other LSDDP demonstrated technologies or ready-for-use commercial technologies will also be considered. The project team will evaluate needs provided by site D&D project managers, match technologies against those needs and rank deployments using a criteria listing. After selecting deployments the project will purchase the equipment and provide a deployment engineer to facilitate the technology implementation. Other cost associated with the use of the technology will be borne by the site including operating staff, safety and health reviews etc. A cost and performance report will be prepared following the deployment to document the results.

  8. Interdisciplinary Project-Based Learning: Technology for Improving Student Cognition

    Science.gov (United States)

    Stozhko, Natalia; Bortnik, Boris; Mironova, Ludmila; Tchernysheva, Albina; Podshivalova, Ekaterina

    2015-01-01

    The article studies a way of enhancing student cognition by using interdisciplinary project-based learning (IPBL) in a higher education institution. IPBL is a creative pedagogic approach allowing students of one area of specialisation to develop projects for students with different academic profiles. The application of this approach in the Ural…

  9. Avionics Technology Contract Project Report Phase I with Research Findings.

    Science.gov (United States)

    Sappe', Hoyt; Squires, Shiela S.

    This document reports on Phase I of a project that examined the occupation of avionics technician, established appropriate committees, and conducted task verification. Results of this phase provide the basic information required to develop the program standards and to guide and set up the committee structure to guide the project. Section 1…

  10. Final Project Summary Report Bechtel Nevada and Fiberchem Environmental, Inc., Cooperative Research and Technology Development Project

    Energy Technology Data Exchange (ETDEWEB)

    R. J. Pollina

    1999-04-01

    This is a report summarizing work on a small project dedicated to adapting a new chemical sensing platform for the US Department of Energy and its customers. At the same time and in the spirit of technology transfer, FCI Environmental, Inc., would receive technical support in the form of expertise from the US Department of Energy to assist in developing this product. The sensor is a hybrid integrated-circuit, optical waveguide, chemical sensor that is patented by FCI Environmental, Inc., and manufactured under license by Texas Instruments, Inc. A down-hole penetrometer probe was designed for use in hot, 60 C, hydrocarbon-saturated, saline environment at a depth of 200 feet. The probe design includes three chemical sensing, hybrid integrated-circuits with chemical reference and measurement channels, a water seal, output electronics, and a removable measurement head for replacement in the field. A hand-held chemical detector prototype--containing a hybrid integrated-circuit chemical sensor with reference channel, user alarm, and level display--was designed and constructed, and a software interface developed to operate the hand-held sensor interfaced with a laboratory data acquisition system.

  11. Advanced Technology MEMS-based Acoustic Array Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Interdisciplinary Consulting Corporation proposes a technological advancement of current state-of-the-art acoustic energy harvester for harsh environment...

  12. Advanced Multimission Operations Systems Tech (AMMOS) Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — AMMOS Technology tasks include: - Enhance mission planning and sequence generation tools with constraint based automated planning and scheduling techniques to enable...

  13. Evaluation of Representative Smart Grid Investment Grant Project Technologies: Distributed Generation

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Ruchi; Vyakaranam, Bharat GNVSR

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of addition of renewable resources- solar and wind in the distribution system as deployed in the SGIG projects.

  14. Review of EOR (enhanced oil recovery) project trends and thermal EOR (enhanced oil recovery) technology

    Energy Technology Data Exchange (ETDEWEB)

    Pautz, J. F.; Sarathi, P.; Thomas, R.

    1990-03-01

    Information on United States (US) enhanced oil recovery (EOR) projects is analyzed to discern trends in applications of EOR technologies. This work is based on an evaluation of current literature and analysis of the Department of Energy (DOE) EOR project data base which contains information on over 1,300 projects. Three-quarters of current US oil production attributed to EOR is derived from thermal EOR processes (TEOR). Changes in the technology of TEOR since the 1984 Enhanced Oil Recovery'' study by the National Petroleum Council (NPC) are reviewed in terms of the current applied technology and reported research. 87 refs., 4 figs., 20 tabs.

  15. Large-scale decontamination and decommissioning technology demonstration project at a former uranium metal production facility

    Energy Technology Data Exchange (ETDEWEB)

    Martineit, R.A.; Borgman, T.D.; Peters, M.S.; Stebbins, L.L. [and others

    1997-03-05

    The Department of Energy`s (DOE) Office of Science and Technology Decontamination and Decommissioning (D&D) Focus Area, led by the Federal Energy Technology Center, has been charged with improving upon baseline D&D technologies with the goal of demonstrating and validating more cost-effective and safer technologies to characterize, deactivate, survey, decontaminate, dismantle, and dispose of surplus structures, buildings, and their contents at DOE sites. The D&D Focus Area`s approach to verifying the benefits of the improved D&D technologies is to use them in large-scale technology demonstration (LSTD) projects at several DOE sites. The Fernald Environmental Management Project (FEMP) was selected to host one of the first three LSTD`s awarded by the D&D Focus Area. The FEMP is a DOE facility near Cincinnati, Ohio, that was formerly engaged in the production of high quality uranium metal. The FEMP is a Superfund site which has completed its RUFS process and is currently undergoing environmental restoration. With the FEMP`s selection to host an LSTD, the FEMP was immediately faced with some challenges. The primary challenge was that this LSTD was to be integrated into the FEMP`s Plant 1 D&D Project which was an ongoing D&D Project for which a firm fixed price contract had been issued to the D&D Contractor. Thus, interferences with the baseline D&D project could have significant financial implications. Other challenges include defining and selecting meaningful technology demonstrations, finding/selecting technology providers, and integrating the technology into the baseline D&D project. To date, twelve technologies have been selected, and six have been demonstrated. The technology demonstrations have yielded a high proportion of {open_quotes}winners.{close_quotes} All demonstrated, technologies will be evaluated for incorporation into the FEMP`s baseline D&D strategy.

  16. Anchored Instruction in Preservice Educational Technology Classes: A Research Project.

    Science.gov (United States)

    Bauer, Jeffrey W.

    This study examined the effectiveness of the anchored instruction (i.e., using a theme or anchor around which various learning activities take place) approach in preparing preservice teachers to integrate technology. Participants were 48 students enrolled in the three sections of a preservice educational technology class during the summer of 1997.…

  17. Examining the Relationship between Technology Leadership Behaviors and Project Success

    Science.gov (United States)

    Bolman, David B.

    2012-01-01

    Organizations invest substantial resources into technology initiatives intended to generate advantages associated with improved use of human resources, increased operational efficiencies, and creating new capacities within processes and products; however, there is limited knowledge regarding how technology leadership behaviors influence project…

  18. FACTORS EFFECTING TECHNOLOGY ACQUISITION DECISIONS IN NATIONAL DEFENSE PROJECTS

    Directory of Open Access Journals (Sweden)

    Gökhan ASTAN

    2015-04-01

    Full Text Available “Defense Industry” (DI not only strengthens the military power of a country, but also effects other fields of technology and economy positively and enables countries to be much more powerful in terms of their competitiveness in technology and knowledge instead of merely being a follower and a continuous customer. If a state seeks to have high-tech and capable DI the only foundation is to create a national environment which is managed based on a systematic ”Technology Management” philosophy and well-defined “Acquisition” process. With already reduced resources, it is crucial to spend money for the most needed and right technology. Consequently, the focus of this study is on the “Acquisition" and "Technology Transfer" (TT concepts and approaches. As such the different TT methods are compared and their advantages and disadvantages discussed. In the last part of the study, DI is described and assessed in terms of the TT methods.

  19. Adaptive Deployable Entry and Placement Technology (ADEPT) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The ADEPT Project is developing a mechanically deployable low-ballistic coefficient aeroshell entry system to perform entry descent landing (EDL) functions for...

  20. Technology Base Research Project for electrochemical energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. (ed.)

    1991-06-01

    This report is an executive summary of major project goals and descriptions for electrochemical energy storage. Exploratory research, applied science research, air systems research, milestones, and management activities are a few of the topics discussed. (JL)

  1. Demonstration of Submillimeter Astrophysics Technology at Caltech Submillimeter Observatory Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The following are the objectives of this project:(1) Demonstration of 1600-element Kinetic Inductance Detector (KID) imaging array operating at 350 micron with near...

  2. Fast GC for Space Applications Based on PIES Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase II project is aimed at the development of an analytical instrument which combines the advantages of fast gas chromatography (GC) and a detector that...

  3. GIS Technology: Resource and Habitability Assessment Tool Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This is a one-year project to apply a GIS analysis tool to new orbital data for lunar resource assessment and martian habitability identification.  We used...

  4. Geometry Projects Linking Mathematics, Literacy, Art, and Technology.

    Science.gov (United States)

    Little, Catherine

    1999-01-01

    Describes a geometry project for students using the Geometer's Sketchpad. Students choose from constructing an instruction manual, writing and illustrating a children's picture book, or creating a piece of art in the Escher style. (ASK)

  5. Operation algorithm of the information system of improving organizational and technological reliability of construction projects using energy efficient technologies

    Directory of Open Access Journals (Sweden)

    Ginzburg Aleksandr Vital’evich

    2016-10-01

    Full Text Available The main source for the development of construction projects with energy-efficient technologies in use is investments. The traditional approaches of risk management: insurance, diversification and redundancy only raise the cost of the construction project, which has a negative impact on the investor’s decision to invest. In order to solve this problem an information system has been developed, which is based on the principle of insightful analysis of the potential “pure” risks and a list of recommendations of risk management. This tool allows identifying all the weaknesses of a construction project, improving the organizational and technological reliability, and imparting an understanding to the investor / a customer of the resources required for the project implementation.

  6. Magnetic levitation technology and its applications in exploration projects

    Science.gov (United States)

    Shu, Quan-Sheng; Cheng, Guangfeng; Susta, Joseph T.; Hull, John R.; Fesmire, James E.; Augustanowicz, Stan D.; Demko, Jonathan A.; Werfel, Frank N.

    2006-02-01

    An energy efficient cryogenic transfer line with magnetic suspension has been prototyped and cryogenically tested. The prototype transfer line exhibits cryogen saving potential of 30-35% in its suspension state as compared to its solid support state. Key technologies developed include novel magnetic levitation using multiple-pole high temperature superconductor (HTS) and rare earth permanent-magnet (PM) elements and a smart cryogenic actuator as the warm support structure. These technologies have vast applications in extremely low thermal leak cryogenic storage/delivery containers, superconducting magnetic bearings, smart thermal switches, etc. This paper reviews the development work and discusses future applications of established technologies.

  7. FACTORS EFFECTING TECHNOLOGY ACQUISITION DECISIONS IN NATIONAL DEFENSE PROJECTS

    OpenAIRE

    2015-01-01

    “Defense Industry” (DI) not only strengthens the military power of a country, but also effects other fields of technology and economy positively and enables countries to be much more powerful in terms of their competitiveness in technology and knowledge instead of merely being a follower and a continuous customer. If a state seeks to have high-tech and capable DI the only foundation is to create a national environment which is managed based on a systematic ”Technology Management” philosophy a...

  8. Phase Change Permeation Technology for Environmental Control & Life Support Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will explore a recent advancement in Phase Change Permeation™ technology to enable improved (1) water recovery from urine/brine for Environmental...

  9. 77 FR 69601 - Science and Technology Reinvention Laboratory (STRL) Personnel Management Demonstration Projects

    Science.gov (United States)

    2012-11-20

    ... of the Secretary Science and Technology Reinvention Laboratory (STRL) Personnel Management Demonstration Projects AGENCY: Office of the Deputy Assistant Secretary of Defense (Civilian Personnel Policy) (DASD (CPP)), Department of Defense (DoD). ACTION: Notice of proposed amendment to demonstration...

  10. 76 FR 1923 - Science and Technology Reinvention Laboratory Personnel Management Demonstration Project...

    Science.gov (United States)

    2011-01-11

    ... organization's human resources management authorities, policies, and practices must have the flexibility needed... contribution-based compensation system, talent acquisition/retention, and professional human capital planning... Defense Science and Technology Reinvention Laboratory Personnel Management Demonstration Project...

  11. Technologies Enabling Exploration of Skylights, Lava Tubes and Caves Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Missions to date have orbited and roved, but sub-planetary worlds elude exploration. This investigation proposes to develop technology for venturing underground and...

  12. Biomedical Monitoring by a Novel Noncontact Radio Frequency Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This technology will be a quantum advance in cardiac monitoring and will be applicable in numerous situations such as for immediate assessment and monitoring of...

  13. Automated Service Discovery using Autonomous Control Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — With the advent of mobile commerce technologies, the realization of pervasive computing and the formation of ad-hoc networks can be leveraged to the benefit of the...

  14. Prototype-Technology Evaluator and Research Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Area-I team has developed and flight tested the unmanned Prototype-Technology Evaluation and Research Aircraft or PTERA ("ptera" being Greek for wing, or...

  15. Lightweight Pump Technology for Advanced Green Monopropellants Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Systima will develop an innovative light weight self-pressurizing pump (SPP) technology to provide a constant-pressure supply of monopropellant to a spacecraft or...

  16. Affordable, Precision Reflector Mold Technology (PDRT08-029) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advances in replication mold technology that reduce material costs, grinding time, and polishing time would enable fabrication of large, precision molds and possibly...

  17. Polymer Matrix Composites using Fused Deposition Modeling Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Fused deposition modeling (FDM) is an additive manufacturing technology that allows fabrication of complex three-dimensional geometries layer-by-layer. The goal of...

  18. Novel Polymer Microfluidics Technology for In Situ Planetary Exploration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Los Gatos Research proposes to develop a new polymer based microfluidics technology for NASA planetary science applications. In particular, we will design, build and...

  19. Calibration/Validation Technology for the CO2 Satellite Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We are proposing to develop high altitude CO2 analyzer technology that can be deployed on the research aircraft of NASA's Airborne Science Program (ASP). The...

  20. Health-Enabled Smart Sensor Fusion Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — It has been proven that the combination of smart sensors with embedded metadata and wireless technologies present real opportunities for significant improvements in...

  1. An MMOD Risk Mitigation Technology for Spacecraft TPS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposed technology uses nitrogen or helium gas and water to prevent structural damage that could lead to loss of vehicle and loss of crew caused by high...

  2. SCINTILLA A European project for the development of scintillation detectors and new technologies for nuclear security

    CERN Document Server

    Alemberti, A; Botta, E; De Vita, R; Fanchini, E; Firpo, G

    2014-01-01

    Europe monitors transits using radiation detectors to prevent illicit trafficking of nuclear materials. The SCINTILLA project aims to develop a toolbox of innovative technologies designed to address different usage cases. This article will review the scope, approach, results of the first benchmark campaign and future plans of the SCINTILLA project.

  3. Profiting from empowerment? Investigating dissemination avenues for educational technology content within an emerging market solutions project

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2005-01-01

    textabstractABSTRACT: The Stills in Sync (SIS) project is a joint initiative of the nonprofit organization PlanetRead and the global information and communication technology (ICT) company Hewlett Packard (HP). The SIS project entails creating a multimedia product designed to enhance literacy in

  4. Becoming Little Scientists: Technologically-Enhanced Project-Based Language Learning

    Science.gov (United States)

    Dooly, Melinda; Sadler, Randall

    2016-01-01

    This article outlines research into innovative language teaching practices that make optimal use of technology and Computer-Mediated Communication (CMC) for an integrated approach to Project-Based Learning. It is based on data compiled during a 10- week language project that employed videoconferencing and "machinima" (short video clips…

  5. Tension awareness of stakeholders in large technology projects : a duality perspective

    NARCIS (Netherlands)

    Boonstra, Albert; van Offenbeek, Marjolein; Vos, Janita F.J.

    2017-01-01

    This paper analyzes the tensions evolving from project management dilemmas and how they relate to stakeholders in large technology projects. The study addresses an organization-wide electronic health record implementation in a large hospital. It adopts a duality lens in exploring whether and how

  6. Virtual Teaming and Collaboration Technology: A Study of Influences on Virtual Project Outcomes

    Science.gov (United States)

    Broils, Gary C.

    2014-01-01

    The purpose of this quantitative correlational study was to explore the relationships between the independent variables, contextual factors for virtual teams and collaboration technology, and the dependent variable, virtual project outcomes. The problem leading to the need for the study is a lower success rate for virtual projects compared to…

  7. 78 FR 34655 - Science and Technology Reinvention Laboratory Personnel Management Demonstration Project...

    Science.gov (United States)

    2013-06-10

    ... of the Secretary Science and Technology Reinvention Laboratory Personnel Management Demonstration... Demonstration Project (75 FR 77380-77447, December 10, 2010). SUMMARY: On December 10, 2010 (75 FR 77380-77447), DoD published a notice of approval of a personnel management demonstration project for eligible...

  8. Tension Awareness of Stakeholders in Large Technology Projects : A Duality Perspective

    NARCIS (Netherlands)

    Boonstra, Albert; van Offenbeek, Marjolein; Vos, Janita F.J.

    2017-01-01

    This article analyzes the tensions evolving from project management dilemmas and how they relate to stakeholders in large technology projects. The study addresses an organization-wide electronic health record implementation in a large hospital. It adopts a duality lens in exploring whether and how

  9. Statistics on Science and Technology in Latin America, Experience with UNESCO Pilot Projects, 1972-1974.

    Science.gov (United States)

    Thebaud, Schiller

    This report examines four UNESCO pilot projects undertaken in 1972 in Brazil, Colombia, Peru, and Uruguay to study the methods used for national statistical surveys of science and technology. The projects specifically addressed the problems of comparing statistics gathered by different methods in different countries. Surveys carried out in Latin…

  10. Profiting from empowerment? Investigating dissemination avenues for educational technology content within an emerging market solutions project

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2005-01-01

    textabstractABSTRACT: The Stills in Sync (SIS) project is a joint initiative of the nonprofit organization PlanetRead and the global information and communication technology (ICT) company Hewlett Packard (HP). The SIS project entails creating a multimedia product designed to enhance literacy in rura

  11. Virtual Teaming and Collaboration Technology: A Study of Influences on Virtual Project Outcomes

    Science.gov (United States)

    Broils, Gary C.

    2014-01-01

    The purpose of this quantitative correlational study was to explore the relationships between the independent variables, contextual factors for virtual teams and collaboration technology, and the dependent variable, virtual project outcomes. The problem leading to the need for the study is a lower success rate for virtual projects compared to…

  12. Scientific and technological progress and innovation of Three Gorges Project%Scientific and technological progress and innovation of Three Gorges Project

    Institute of Scientific and Technical Information of China (English)

    Zhang Chaoran; Sun Zhiyu

    2011-01-01

    In the design, construction and operation periods of the Three Gorges Project (TGP), great challenges have been met in different fields such as water resources and hydropower project construction, electromechanical equipment manufacture and ecological environment protection. In view of the key techniques and difficulties in the construction period, scientific and technological breakthroughs have been made by the experts and scholars of various fields and a series of innovative achievements are gained, which make the scientific and technological levels in relevant fields improved. Some major innovative achievements in the construction and operation of TGP are enumerated, which are significant for the hydropower project construction and clean energy development in the future in China.

  13. Technological and regulatory aspects of quality management during the life cycle of investment and construction projects

    Directory of Open Access Journals (Sweden)

    Kropyvko Serhii Maksymovych

    2016-12-01

    Full Text Available The division of the life cycle of investment and construction projects in four phases, based on their technological features, is proposed in the article. Regulatory aspects of quality management during each phase of the life cycle of investment and construction projects are analyzed. The model of quality management during the phases of the life cycle of investment and construction project is developed.

  14. Diagnostic framework and health check tool for engineering and technology projects

    Directory of Open Access Journals (Sweden)

    Simon P Philbin

    2014-10-01

    Full Text Available Purpose: Development of a practitioner oriented diagnostic framework and health check tool to support the robust assessment of engineering and technology projects.Design/methodology/approach: The research is based on a literature review that draws together insights on project assessment and critical success factors to establish an integrated systems view of projects. This is extended to allow a comprehensive diagnostic framework to be developed along with a high-level health check tool that can be readily deployed on projects. The utility of the diagnostic framework and health check tool are explored through three illustrative case studies, with two from Canada and one from the United Kingdom. Findings andOriginality/value: The performance of engineering and technology projects can be viewed through a systems perspective and being a function of six sub-systems that are: process, technology, resources, impact, knowledge and culture. The diagnostic framework that is developed through this research integrates these sub-systems to provide a comprehensive assessment methodology for projects, which is linked to existing best practice for project reviews, performance management and maturity models. The case studies provide managerial insights that are related to the diagnostic framework but crucially also position the approach in the context of industrial applications for construction engineering and technology management.Research limitations/implications: The case study approach includes two case studies from the construction and facilities development sector with the third case study from the research and technology sector. Further work is required to investigate the use of the diagnostic framework and health check tool in other sectors.Practical implications: The health check tool will be of practical benefit to new projects managers that require access to a robust and convenient project review methodology for assessing the status and health of a

  15. A Survey of Technologies Supporting Virtual Project Based Learning

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Lone

    2002-01-01

    for evaluation is proposed where negotiation of meaning, coordination and resource management are identified as the key concepts in virtual project based learning. Three e-learning systems are selected for the survey, Virtual-U, Lotus Learningspace and Lotus Quickplace, as each system offers different strategies...

  16. Industrial Technology Modernization Program. Project 32. Factory Vision. Phase 2

    Science.gov (United States)

    1988-04-01

    400B is through floppy disk media . On the shop floor, a set-up person is responsible for setting up the machines. The set-up person must look at the...million dollars. An additional five millon dollars of projected savings would be associated with the incorporation of the fifth cell for the same ten

  17. Study on the Factors Influencing the Level of Innovation in Agricultural Science and Technology Projects

    Institute of Scientific and Technical Information of China (English)

    Jing; SUN; Baofeng; CHEN

    2015-01-01

    This paper carries out a questionnaire survey of persons in charge of the agricultural project in the " Eleventh Five-Year National Support Program" on the level of innovation in projects and the factors influencing innovation. After the linear regression analysis of the survey data,it is found that the factors influencing the innovation in agricultural science and technology projects include the level of innovation in scientific achievements,efficiency of research methods and creation of innovation environment. Through the variance analysis of the level of innovation and its influencing factors related to different innovators,it is found that there are differences in the statistical significance of level of innovation in projects among universities,research institutes,research and extension departments directly under the government,and enterprises; there are no significant differences in the understanding of factors influencing innovation,that is,different innovators basically have the same understanding of factors influencing innovation,but the assessment on level of innovation in projects completed is different to some extent.On this basis,this paper proposes the recommendations for further strengthening the level of innovation in agricultural science and technology projects in order to provide a theoretical reference and practical basis for the project managers to effectively improve the level of agricultural science and technology project management,and enhance the level of innovation in projects.

  18. Exploring the Effects of Technology Overload on the Outcomes of Enterprise Resource Planning (ERP) Implementation Projects

    Science.gov (United States)

    Kates, Earl B.

    2016-01-01

    Despite significant investments made by organizations to implement ERP systems and prior research that explored contributing factors of ERP failure, the ERP implementation success rate continues to remain low in practice. Increased technology usage in the workplace coupled with higher dependency on technology to complete project tasks often leads…

  19. PROJECT W-551 INTERIM PRETREATMENT SYSTEM TECHNOLOGY SELECTION SUMMARY DECISION REPORT AND RECOMMENDATION

    Energy Technology Data Exchange (ETDEWEB)

    CONRAD EA

    2008-08-12

    This report provides the conclusions of the tank farm interim pretreatment technology decision process. It documents the methodology, data, and results of the selection of cross-flow filtration and ion exchange technologies for implementation in project W-551, Interim Pretreatment System. This selection resulted from the evaluation of specific scope criteria using quantitative and qualitative analyses, group workshops, and technical expert personnel.

  20. A Constructivist Stretch: Preservice Teachers Meet Preteens in a Technology-Based Literacy Project.

    Science.gov (United States)

    Bauer, John F.; Anderson, Rebecca S.

    2002-01-01

    Describes a study conducted within a constructivist framework to examine pre-service teachers' development and implementation of a collaborative, technology-based literacy project with 11- and 12-year-old learners. Concludes that the pre-service teachers learned the value of Internet technology, e-mail, and hypermedia applications, but problems…

  1. Current status and future tasks of the Sunshine Project. (Development of new energy technology)

    Energy Technology Data Exchange (ETDEWEB)

    Takada, T.

    1983-01-01

    Since its inception in 1974, the Sunshine Project has involved advances in new energy technology in many areas. The present report covers the principal areas of activity in 1980, examining the development status of solar energy, goethermal energy, coal liquefaction and gasification, hydrogen energy, wind power, ocean thermal energy conversion, etc. Future trends and tasks of new energy technology development are discussed. (In Japanese)

  2. Progress of Project “The Key Technology Research of Passive Shutdown System for CDFR”

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Passive shutdown technology is one of the key technologies to increase safety performance of larger-size sodium-cooled fast reactors. The objective to the project was to develop the preliminary design of the rod on the basis of theoretic analysis of passive shutdown assembly.

  3. Exploring the Effects of Technology Overload on the Outcomes of Enterprise Resource Planning (ERP) Implementation Projects

    Science.gov (United States)

    Kates, Earl B.

    2016-01-01

    Despite significant investments made by organizations to implement ERP systems and prior research that explored contributing factors of ERP failure, the ERP implementation success rate continues to remain low in practice. Increased technology usage in the workplace coupled with higher dependency on technology to complete project tasks often leads…

  4. PROJECT W-551 INTERIM PRETREATMENT SYSTEM PRECONCEPTUAL CANDIDATE TECHNOLOGY DESCRIPTIONS

    Energy Technology Data Exchange (ETDEWEB)

    MAY TH

    2008-08-12

    The Office of River Protection (ORP) has authorized a study to recommend and select options for interim pretreatment of tank waste and support Waste Treatment Plant (WTP) low activity waste (LAW) operations prior to startup of all the WTP facilities. The Interim Pretreatment System (IPS) is to be a moderately sized system which separates entrained solids and 137Cs from tank waste for an interim time period while WTP high level waste vitrification and pretreatment facilities are completed. This study's objective is to prepare pre-conceptual technology descriptions that expand the technical detail for selected solid and cesium separation technologies. This revision includes information on additional feed tanks.

  5. A project in support of Nuclear Technology Cooperation

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Ki Jung; Choi, Pyong Hoon; Yi, Ji Ho (and others)

    2005-12-15

    Establish the integrated management system of information resources and to automate business flow and to improve business productivity through efficient information sharing. - Promotion of domestic nuclear energy technology by utilizing nuclear energy informations and computer software developed in the advanced countries. - Establish strategies of international cooperation in an effort to promote our nation's Leading role in international society, to form the foundation for the effective transfer of nuclear technology to developing countries, and to cope with the rapidly changing international nuclear climate.

  6. TRAMS Project: variability and reliability of SRAM memories in sub-22nm bulk-CMOS technologies

    OpenAIRE

    2011-01-01

    The TRAMS (Terascale Reliable Adaptive MEMORY Systems) project addresses in an evolutionary way the ultimate CMOS scaling technologies and paves the way for revolutionary, most promising beyond-CMOS technologies. In this abstract we show the significant variability levels of future 18 and 13 nm device bulk-CMOS technologies as well as its dramatic effect on the yield of memory cells and circuits. Peer Reviewed

  7. White House Technology Reinvestment Project Briefing And Transcripts

    Science.gov (United States)

    1993-04-12

    Technology Development, is in the SBIR are two entirely separate Cartier Room, which is to your right. concepts. I’m sorry, Deployment. I’m sorry, MR. GUDAS...libraries whereby access is provided to to lay up, both polymer , metal matrix a large number of people and ways in and ceramic matrix composites are

  8. ATTAP: Advanced Turbine Technology Applications Project. Annual report, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Purpose of ATTAP is to bring the automotive gas turbine engine to a technology state at which industry can make commercialization decisions. Activities during the past year included test-bed engine design and development, ceramic component design, materials and component characterization, ceramic component process development and fabrication, ceramic component rig testing, and test-bed engine fabrication and testing.

  9. Propulsion Noise Reduction Research in the NASA Advanced Air Transport Technology Project

    Science.gov (United States)

    Van Zante, Dale; Nark, Douglas; Fernandez, Hamilton

    2017-01-01

    The Aircraft Noise Reduction (ANR) sub-project is focused on the generation, development, and testing of component noise reduction technologies progressing toward the NASA far term noise goals while providing associated near and mid-term benefits. The ANR sub-project has efforts in airframe noise reduction, propulsion (including fan and core) noise reduction, acoustic liner technology, and propulsion airframe aeroacoustics for candidate conventional and unconventional aircraft configurations. The current suite of propulsion specific noise research areas is reviewed along with emerging facility and measurement capabilities. In the longer term, the changes in engine and aircraft configuration will influence the suite of technologies necessary to reduce noise in next generation systems.

  10. Expedited technology demonstration project final report: final forms

    Energy Technology Data Exchange (ETDEWEB)

    Hopper, R W

    1999-05-01

    ETDP Final Forms was an attempt to demonstrate the fabrication and performance of a ceramic waste form immobilizing the hazardous and radioactive elements of the MSO/SR mineral residues. The ceramic material had been developed previously. The fabrication system was constructed and functioned as designed except for the granulator. Fabrication of our particular ceramic, however, proved unsatisfactory. The ceramic material design was therefore changed toward the end of the project, replacing nepheline with zircon as the sink for silica. Preliminary results were encouraging, but more development is needed. Fabrication of the new ceramic requires major changes in the processing: Calcination and granulation would be replaced by spray drying; and sintering would be at higher temperature. The main goal of the project--demonstrating the fabrication and performance of the waste form--was not achieved. This report summarizes Final Forms' activities. The problem of immobilizing the MSO/SR mineral residues is discussed.

  11. CO2 CAPTURE PROJECT - AN INTEGRATED, COLLABORATIVE TECHNOLOGY DEVELOPMENT PROJECT FOR NEXT GENERATION CO2 SEPARATION, CAPTURE AND GEOLOGIC SEQUESTRATION

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Helen Kerr

    2003-08-01

    The CO{sub 2} Capture Project (CCP) is a joint industry project, funded by eight energy companies (BP, ChevronTexaco, EnCana, Eni, Norsk Hydro, Shell, Statoil, and Suncor) and three government agencies (1) European Union (DG Res & DG Tren), (2) Norway (Klimatek) and (3) the U.S.A. (Department of Energy). The project objective is to develop new technologies, which could reduce the cost of CO{sub 2} capture and geologic storage by 50% for retrofit to existing plants and 75% for new-build plants. Technologies are to be developed to ''proof of concept'' stage by the end of 2003. The project budget is approximately $24 million over 3 years and the work program is divided into eight major activity areas: (1) Baseline Design and Cost Estimation--defined the uncontrolled emissions from each facility and estimate the cost of abatement in $/tonne CO{sub 2}. (2) Capture Technology, Post Combustion: technologies, which can remove CO{sub 2} from exhaust gases after combustion. (3) Capture Technology, Oxyfuel: where oxygen is separated from the air and then burned with hydrocarbons to produce an exhaust with high CO{sub 2} for storage. (4) Capture Technology, Pre -Combustion: in which, natural gas and petroleum coke are converted to hydrogen and CO{sub 2} in a reformer/gasifier. (5) Common Economic Model/Technology Screening: analysis and evaluation of each technology applied to the scenarios to provide meaningful and consistent comparison. (6) New Technology Cost Estimation: on a consistent basis with the baseline above, to demonstrate cost reductions. (7) Geologic Storage, Monitoring and Verification (SMV): providing assurance that CO{sub 2} can be safely stored in geologic formations over the long term. (8) Non-Technical: project management, communication of results and a review of current policies and incentives governing CO{sub 2} capture and storage. Technology development work dominated the past six months of the project. Numerous studies are making

  12. Manufacturing Methods & Technology Project Execution Report. Second Half CY 1980

    Science.gov (United States)

    1981-03-01

    U.S. ARMY MATER-IEL DEVELOP AND READINESS COMMAND Lu ti MAANUFACTURING METHODS & 0 ~ ECHNOLOGY ELECTE, hAY 4 19 81 PROJECT EXECUTION REPORTautw w...Armament Materiel Readiness Command (Ammunition) . ... 83 Armament R&D Cormtand Armament Materiel Readiness Command (Weapons) .. . . . 105 Mobility ... MOBILIZATION PRODUCTION RATES ARE ESTIMATED TO BE S1t6 6000 PER YEAR. 5 78 4288 EXPLOSIVE SAFE SEPARATION AND SENSITIVITY CRITERIA ZERO PALLET SPACING

  13. Telecommunication Technologies for Smart Grid Projects with Focus on Smart Metering Applications

    Directory of Open Access Journals (Sweden)

    Nikoleta Andreadou

    2016-05-01

    Full Text Available This paper provides a study of the smart grid projects realised in Europe and presents their technological solutions with a focus on smart metering Low Voltage (LV applications. Special attention is given to the telecommunications technologies used. For this purpose, we present the telecommunication technologies chosen by several European utilities for the accomplishment of their smart meter national roll-outs. Further on, a study is performed based on the European Smart Grid Projects, highlighting their technological options. The range of the projects analysed covers the ones including smart metering implementation as well as those in which smart metering applications play a significant role in the overall project success. The survey reveals that various topics are directly or indirectly linked to smart metering applications, like smart home/building, energy management, grid monitoring and integration of Renewable Energy Sources (RES. Therefore, the technological options that lie behind such projects are pointed out. For reasons of completeness, we also present the main characteristics of the telecommunication technologies that are found to be used in practice for the LV grid.

  14. Tehachapi Wind Energy Storage Project - Technology Performance Report #3

    Energy Technology Data Exchange (ETDEWEB)

    Pinsky, Naum [Southern California Edison, Rosemead, CA (United States); O' Neill, Lori [Southern California Edison, Rosemead, CA (United States)

    2017-03-31

    The TSP is located at SCE’s Monolith Substation in Tehachapi, California. The 8 MW, 4 hours (32 MWh) BESS is housed in a 6,300 square foot facility and 2 x 4 MW/4.5 MVA smart inverters are on a concrete pad adjacent to the BESS facility. The project will evaluate the capabilities of the BESS to improve grid performance and assist in the integration of large-scale intermittent generation, e.g., wind. Project performance was measured by 13 specific operational uses: providing voltage support and grid stabilization, decreasing transmission losses, diminishing congestion, increasing system reliability, deferring transmission investment, optimizing renewable-related transmission, providing system capacity and resources adequacy, integrating renewable energy (smoothing), shifting wind generation output, frequency regulation, spin/non-spin replacement reserves, ramp management, and energy price arbitrage. Most of the operations either shift other generation resources to meet peak load and other electricity system needs with stored electricity, or resolve grid stability and capacity concerns that result from the interconnection of intermittent generation. SCE also demonstrated the ability of lithium ion battery storage to provide nearly instantaneous maximum capacity for supply-side ramp rate control to minimize the need for fossil fuel-powered back-up generation. The project began in October, 2010 and will continue through December, 2016.

  15. A forward looking approach to project management tools, trends, and the impact of disruptive technologies

    CERN Document Server

    Gurjar, Nikhil

    2017-01-01

    This book is intended as a basis for advanced treatment of concepts in project management. In the current scenario where most questions are answered through the internet, the knowledge element in project management has come under the influence of disruptive technologies. In other words, project managers no longer get 'points' for knowing something that is easily available on the internet. This has far-reaching consequences. The present day project managers need to orient themselves to newer benchmarks of what is required for success on the business front. This book deals with a few such advanced concepts in project management. This book is not designed as an elementary primer to the field of project management, rather it is an advanced level treatment on the subject, to be read after the preliminary study has already been completed. The book is designed for practicing project managers, and graduate students in engineering and management, who need to understand the dynamics that are typically encountered in a ...

  16. Regulation of Phosphatidylethanolamine Homeostasis — The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2

    Directory of Open Access Journals (Sweden)

    Zvezdan Pavlovic

    2013-01-01

    Full Text Available Phosphatidylethanolamine (PE is the most abundant lipid on the protoplasmatic leaflet of cellular membranes. It has a pivotal role in cellular processes such as membrane fusion, cell cycle regulation, autophagy, and apoptosis. CTP:phosphoethanolamine cytidylyltransferase (Pcyt2 is the main regulatory enzyme in de novo biosynthesis of PE from ethanolamine and diacylglycerol by the CDP-ethanolamine Kennedy pathway. The following is a summary of the current state of knowledge on Pcyt2 and how splicing and isoform specific differences could lead to variations in functional properties in this family of enzymes. Results from the most recent studies on Pcyt2 transcriptional regulation, promoter function, autophagy, and cell growth regulation are highlighted. Recent data obtained from Pcyt2 knockout mouse models is also presented, demonstrating the essentiality of this gene in embryonic development as well as the major physiological consequences of deletion of one Pcyt2 allele. Those include development of symptoms of the metabolic syndrome such as elevated lipogenesis and lipoprotein secretion, hypertriglyceridemia, liver steatosis, obesity, and insulin resistance. The objective of this review is to elucidate the nature of Pcyt2 regulation by linking its catalytic function with the regulation of lipid and energy homeostasis.

  17. The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.

    Science.gov (United States)

    Fullerton, Morgan D; Hakimuddin, Fatima; Bonen, Arend; Bakovic, Marica

    2009-09-18

    Phosphatidylethanolamine (PE) is an important inner membrane phospholipid mostly synthesized de novo via the PE-Kennedy pathway and by the decarboxylation of phosphatidylserine. CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) catalyzes the formation of CDP-ethanolamine, which is often the rate regulatory step in the PE-Kennedy pathway. In the current investigation, we show that the reduced CDP-ethanolamine formation in Pcyt2(+/-) mice limits the rate of PE synthesis and increases the availability of diacylglycerol. This results in the increased formation of triglycerides, which is facilitated by stimulated de novo fatty acid synthesis and increased uptake of pre-existing fatty acids. Pcyt2(+/-) mice progressively accumulate more diacylglycerol and triglycerides with age and have modified fatty acid composition, predominantly in PE and triglycerides. Pcyt2(+/-) additionally have an inherent blockage in fatty acid utilization as energy substrate and develop impaired tolerance to glucose and insulin at an older age. Accordingly, gene expression analyses demonstrated the up-regulation of the main lipogenic genes and down-regulation of mitochondrial fatty acid beta-oxidation genes. These data demonstrate for the first time that to preserve membrane PE phospholipids, Pcyt2 deficiency generates compensatory changes in triglyceride and energy substrate metabolism, resulting in a progressive development of liver steatosis, hypertriglyceridemia, obesity, and insulin resistance, the main features of the metabolic syndrome.

  18. Male-Specific Cardiac Dysfunction in CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)-Deficient Mice.

    Science.gov (United States)

    Basu, Poulami; Alibhai, Faisal J; Tsimakouridze, Elena V; Singh, Ratnesh K; Paglialunga, Sabina; Holloway, Graham P; Martino, Tami A; Bakovic, Marica

    2015-08-01

    Phosphatidylethanolamine (PE) is the most abundant inner membrane phospholipid. PE synthesis from ethanolamine and diacylglycerol is regulated primarily by CTP:phosphoethanolamine cytidylyltransferase (Pcyt2). Pcyt2(+/-) mice have reduced PE synthesis and, as a consequence, perturbed glucose and fatty acid metabolism, which gradually leads to the development of hyperlipidemia, obesity, and insulin resistance. Glucose and fatty acid uptake and the corresponding transporters Glut4 and Cd36 are similarly impaired in male and female Pcyt2(+/-) hearts. These mice also have similarly reduced phosphatidylinositol 3-kinase (PI3K)/Akt1 signaling and increased reactive oxygen species (ROS) production in the heart. However, only Pcyt2(+/-) males develop hypertension and cardiac hypertrophy. Pcyt2(+/-) males have upregulated heart AceI expression, heart phospholipids enriched in arachidonic acid and other n-6 polyunsaturated fatty acids, and dramatically increased ROS production in the aorta. In contrast, Pcyt2(+/-) females have unmodified heart phospholipids but have reduced heart triglyceride levels and altered expression of the structural genes Acta (low) and Myh7 (high). These changes together protect Pcyt2(+/-) females from cardiac dysfunction under conditions of reduced glucose and fatty acid uptake and heart insulin resistance. Our data identify Pcyt2 and membrane PE biogenesis as important determinants of gender-specific differences in cardiac lipids and heart function. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  19. Infliximab Biosimilar (CT-P13; Infliximab-dyyb): A Review in Autoimmune Inflammatory Diseases.

    Science.gov (United States)

    Blair, Hannah A; Deeks, Emma D

    2016-10-01

    Infliximab biosimilar (CT-P13/infliximab-dyyb; Remsima(®), Inflectra(®)) is approved in several countries for use in all indications for which reference infliximab (Remicade(®)) is approved, including rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis, psoriasis, Crohn's disease, and ulcerative colitis. Clinical data contributing to the EU approval of infliximab biosimilar were obtained from two pivotal double-blind clinical trials in patients with AS (PLANETAS) or RA (PLANETRA). Infliximab biosimilar demonstrated equivalence to reference infliximab in terms of its pharmacokinetic profile in patients with AS, patients with RA, and in healthy volunteers, and in terms of its efficacy in patients with RA. Clinical response rates in patients with RA or AS were maintained over the longer term (up to 102 weeks). In addition, the efficacy of infliximab biosimilar in patients with RA or Crohn's disease and ulcerative colitis [i.e. inflammatory bowel disease (IBD)] has been demonstrated in the real-world setting. Infliximab biosimilar was generally well tolerated, with a tolerability profile similar to that of reference infliximab. Switching from reference infliximab to infliximab biosimilar had no detrimental effect on efficacy, safety, or immunogenicity compared with continuous infliximab biosimilar therapy, according to the extensions of PLANETAS and PLANETRA, and real-world data in IBD. Current evidence therefore suggests that infliximab biosimilar is a useful alternative to reference infliximab in patients with autoimmune inflammatory diseases.

  20. Progress in biosimilar monoclonal antibody development: the infliximab biosimilar CT-P13 in the treatment of rheumatic diseases.

    Science.gov (United States)

    Braun, Jürgen; Kudrin, Alex

    2015-01-01

    Biosimilars are biologic medical products whose active drug substance is made by a living organism or derived from it. The term is used to describe a subsequent version of an innovator biopharmaceutical product aiming at approval following patent expiry on the reference product. Biosimilars of monoclonal need to demonstrate similar but not identical quality of nonclinical and clinical attributes. Not all data of the originator product need to be recapitulated, as large numbers of patient-years of exposure data are already available. Thus, biosimilar development is largely based on the safety profiles of the originator product. The evaluation of biosimilarity includes immunogenicity attributed risks. CT-P13 (Remsima™/Inflectra™, Celltrion/Hospira), a biosimilar of the innovator drug infliximab (INF), was the first approved complex biosimilar monoclonal antibody in the EU, within the framework of WHO, EMA and US FDA biosimilar guidelines. CT-P13 has shown analytical and nonclinical features highly similar to INF including pharmacokinetics, efficacy, safety and immunogenicity profiles in ankylosing spondylitis and rheumatoid arthritis. The objective of this article is to highlight the recent biosimilar development and to review the results from the studies PLANETRA and PLANETAS, which have supported the approval of CT-P13 for several indications.

  1. Usefulness of three-dimensional CT pancreatography (3D-CTP) after the balloon-ERP for pancreatic diseases

    Energy Technology Data Exchange (ETDEWEB)

    Ueki, Toshiharu; Oishi, Yayoi; Sakaguchi, Seigo; Sakurai, Toshihiro; Yao, Tsuneyoshi [Fukuoka Univ., Chikushino (Japan). Chikushi Hospital; Ichimaru, Yoshihiko; Koga, Yuki; Ikeda, Seiyo

    1998-03-01

    The clinical usefulness of 3D-CTP combined with the balloon-ERP and helical-CT was discussed. Authors diagnosed 42 patients with pancreatic diseases, including 5 of pancreatic carcinoma, 3 of serous cystadenoma, 6 of muciparous pancreatic cyst, 28 of chronic pancreatitis (including 8 cases of complicated pseudocyst). The images could reconstruct three-dimensionally the tapering constriction in the main pancreatic duct for all 5 cases of pancreatic carcinoma, the exclusion in the main pancreatic duct for 3 cases of serous cystadenoma and 1 case of muciparous pancreatic cyst, the parietal irregularity for 14 cases and the smooth constriction for 9 cases in main pancreatic duct of chronic pancreatitis, the morphology of the cyst and the spatial relationship between the cyst and the pancreatic duct in 5 of 6 cases of muciparous pancreatic cyst and 7 of 8 cases of complicated pseudocyst. Furthermore, the 3D-CTP could demonstrate the branched pancreatic duct at the constriction site which was not detected by the balloon-ERP in 2 cases of chronic pancreatitis with the constriction at the main pancreatic duct, and the joining manner of cyst to the pancreatic duct which was indistinct by the balloon-ERP in 6 cases of pancreatic cyst. These results show that 3D-CTP is useful for the qualitative diagnosis and applicable for the understanding of pancreatic diseases and for the simulation of surgery. (K.H.)

  2. WEB 2.0 TECHNOLOGIES IN ENTERPRISES AND PROJECT MANAGEMENT: ANALISYS AND A RESEARCH AGENDA

    Directory of Open Access Journals (Sweden)

    Marcirio Silveira Chaves.

    2015-06-01

    Full Text Available Web 2.0 technologies, e.g. wikis, social networks and blogs, have gained attention by companies and start being incorporated into project management in recent years. It is known that for the effective use of these technologies, project managers must overcome some barriers, such as: a. To adapt to the organizational culture and the culture of the company's employees; b. Check the knowledge of employees on the use of these tools; c. Provide adequate training before use; d. Re-evaluate the data storage structure, i.e. hardware and software; e. Improving communication between project developers. The objectives of this paper are twofold: 1. To analyze the use of IT 2.0 in business and project management and 2. To provide a research agenda on IT 2.0 use in project management. The research is characterized as exploratory and descriptive. As a result, the researchers receive an agenda to guide research on how to apply IT 2.0 in projects, while contributing to the practice allows project managers have a broad view of how such technologies are being used and how they can be used in years come. In addition, this paper seeks to disseminate the new field of Project Management 2.0.

  3. Improvement of Project Portfolio Management in an Information Technology Consulting Company

    Science.gov (United States)

    Kaewta, S.; Chutima, P.

    2014-06-01

    The scope of this research is to improve the efficiency of multiple project management in an information technology consulting company through the adaptation of the project portfolio management technique. The project management information system (PMIS) is implemented to establish effective communication channels so that internal and external teams as well as all relevant stakeholders can be employed to negotiate their work schedules. In addition, all activities created by multiple teams can be systematically reviewed and combined into a single checklist to be used as an agreed working plan for all team members. A general guideline for project portfolio management in information technology consulting companies is also proposed, which could results in a higher level of project on-time delivery.

  4. The Technology Reinvestment Project: Integrating Military and Civilian Industries

    Science.gov (United States)

    1993-07-01

    Extension Partnership Program 68 C-4. Department of Energy R&D Budgets by Mission 70 C-5. NASA Research and Development Budget 71 C-6. National Science...significantly the layoffs that will take place over the next few years because of cutbacks in defense spending. The technology programs may, however... layoffs that will take place over the next few years because of cutbacks in defense spending. The defense budget cutbacks proposed by the Clinton

  5. A Project in Support of Nuclear Technology Cooperation

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Deok Ku; Kim, Kyoung Pyo; Ko, Young Chel (and others)

    2006-12-15

    Establish strategies of international cooperation in an effect to promote our nation's leading role in international society, to form the foundation for the effective transfer of nuclear technology to developing countries, and to cope with the rapidly changing international nuclear climate. Using the INIS output data, it has provided domestic users with searching. Establish the integrated management system of information resources and to automate business flow and to improve business productivity through efficient information sharing.

  6. A multicentre randomised controlled trial to compare the pharmacokinetics, efficacy and safety of CT-P10 and innovator rituximab in patients with rheumatoid arthritis

    Science.gov (United States)

    Yoo, Dae Hyun; Suh, Chang-Hee; Shim, Seung Cheol; Jeka, Slawomir; Cons-Molina, Francisco Fidencio; Hrycaj, Pawel; Wiland, Piotr; Lee, Eun Young; Medina-Rodriguez, Francisco G; Shesternya, Pavel; Radominski, Sebastiao; Stanislav, Marina; Kovalenko, Volodymyr; Sheen, Dong Hyuk; Myasoutova, Leysan; Lim, Mie Jin; Choe, Jung-Yoon; Lee, Sang Joon; Lee, Sung Young; Kwon, Taek Sang; Park, Won

    2017-01-01

    Objective To demonstrate pharmacokinetic equivalence of CT-P10 and innovator rituximab (RTX) in patients with rheumatoid arthritis (RA) with inadequate responses or intolerances to antitumour necrosis factor agents. Methods In this randomised phase I trial, patients with active RA were randomly assigned (2:1) to receive 1000 mg CT-P10 or RTX at weeks 0 and 2 (alongside continued methotrexate therapy). Primary endpoints were area under the serum concentration–time curve from time zero to last quantifiable concentration (AUC0–last) and maximum serum concentration after second infusion (Cmax). Additional pharmacokinetic parameters, efficacy, pharmacodynamics, immunogenicity and safety were also assessed. Data are reported up to week 24. Results 103 patients were assigned to CT-P10 and 51 to RTX. The 90% CIs for the ratio of geometric means (CT-P10/RTX) for both primary endpoints were within the bioequivalence range of 80%–125% (AUC0–last: 97.7% (90% CI 89.2% to 107.0%); Cmax: 97.6% (90% CI 92.0% to 103.5%)). Pharmacodynamics and efficacy were comparable between groups. Antidrug antibodies were detected in 17.6% of patients in each group at week 24. CT-P10 and RTX displayed similar safety profiles. Conclusions CT-P10 and RTX demonstrated equivalent pharmacokinetics and comparable efficacy, pharmacodynamics, immunogenicity and safety. Trial registration number NCT01534884. PMID:27624791

  7. An Empirical Analysis of Technology Transfer of National R&D Projects in South Korea

    Directory of Open Access Journals (Sweden)

    Mi-Sun Kim

    2015-01-01

    Full Text Available This study is aimed at seeking policy implications for the policy makers of South Korean government and finding a direction to support R&D institutions in performing R&D activities more efficiently, by analyzing the factors influencing technology transfer of the national R&D projects. The data retrieved from NTIS (National Science & Technology Information Service was used in analyzing the results of 575 projects with 1,903 cases of technology transfer, performed by the Ministry of Science, ICT and Future Planning, between 2002 and 2012. We found that there were significant differences between the government funded institutions and the universities and between basic R&D and applied ones. We also discovered that the government funded institutions did not necessarily take a better position than the universities in terms of the quantity of technology transfer. Lastly, the applied R&D of the universities was very vulnerable in terms of technology transfer.

  8. Minimal Technologies Application Project, Hohenfels Training Area, Germany: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O. [Argonne National Lab., IL (United States). Energy Systems Div.; Severinghaus, W.D. [Corps of Engineers, Champaign, IL (United States); Brent, J.J. [Army Construction Engineering Research Lab., Champaign, IL (United States)

    1991-12-01

    At the US Army Hohenfels Training Area in Germany, more than 30 years of continuous and intensive tactical training has caused extensive environmental damage because of the loss of vegetative cover and accelerated soil erosion. A project was conducted to evaluate the cost-effectiveness and relative benefits of various revegetation procedures. These procedures involved amendment and seedbed preparation options that were combined with three different durations of site closure. The point-intercept method was used to measure the types and amounts of vegetation established and changes in the vegetative community. Over three growing seasons, applications of fertilizer and seed increased the percent grass, legume, and total vegetative cover. The duration of site closure had no influence on the types or amounts of ground cover established. Materials made up only 10% of the total cost of the fertilization and seeding operations. The results of the research indicate that less expensive methods of amendment application should be evaluated. The data also show that site closure is not practical, economical, or necessary. The results of this project suggest that a regular maintenance program consisting of seeding and fertilization is required to maintain adequate vegetative cover and control erosion on tactical training areas.

  9. Aviation Safety Program Atmospheric Environment Safety Technologies (AEST) Project

    Science.gov (United States)

    Colantonio, Ron

    2011-01-01

    Engine Icing: Characterization and Simulation Capability: Develop knowledge bases, analysis methods, and simulation tools needed to address the problem of engine icing; in particular, ice-crystal icing Airframe Icing Simulation and Engineering Tool Capability: Develop and demonstrate 3-D capability to simulate and model airframe ice accretion and related aerodynamic performance degradation for current and future aircraft configurations in an expanded icing environment that includes freezing drizzle/rain Atmospheric Hazard Sensing and Mitigation Technology Capability: Improve and expand remote sensing and mitigation of hazardous atmospheric environments and phenomena

  10. LNG - Status in Denmark. Technology and potential. Project report

    Energy Technology Data Exchange (ETDEWEB)

    Naeslund, M.

    2012-05-15

    The interest for LNG both on a small and a large scale is increasing worldwide. The experiences and knowledge on LNG is limited in Denmark. The Danish gas companies' Technical Management Group (TCG) has asked for a status report including a technology description and an evaluation of the potential in Denmark. A survey of primarily small-scale LNG technology is done in the report. The focus is motivated by the new areas of gas utilisation that become possible with small-scale LNG. Small-scale LNG in this study is defined as LNG stored and used at the application or in an isolated gas grid. The small-scale use of LNG has today an almost negligible share of the total LNG trade but offers interesting new applications for gas utilisation. LNG on a small scale can be used primarily as: 1) Ship fuel. 2) Truck fuel (heavy duty long distance). 3) Individual users not connected to the natural gas grid. 4) Backup for upgraded biogas to individual users and vehicle fleets. 5) Security of supply or supply enhancement of heavily loaded parts of the gas grid. 6) Small-scale storage and/or peak shaving. All but the first topics are natural uses for the current Danish gas distributors. LNG as ship fuel may engage other specialized LNG companies. The report contains a technical description of the parts in primarily small-scale LNG handling and operation. Liquefaction, transport, storage, engine technologies, gas quality and safety aspects related to LNG are covered. There seem to be two more or less separate paths for LNG in Denmark, onshore and off-shore use. These are not, apparently, sharing their experiences and knowledge. Rules and regulations are also different which may create some problems in the interface, for example ship bunkering. Further studies are suggested in the area of gas quality and engine technologies and adaptation of foreign guidelines for small-scale installations to Danish conditions. These guidelines ought to be based on international standards and

  11. Real Time Technology Application Demonstration Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Volpe, John [Univ of KY, Center for Applied Energy Research, Kentucky Research Consortium for Energy and Environment; Hampson, Steve [Univ of KY, Center for Applied Energy Research, Kentucky Research Consortium for Energy and Environment; Johnson, Robert L [Argonne National Lab, Environmental Science Div.

    2008-09-01

    The work and results described in this final report pertain to the demonstration of real-time characterization technologies applied to potentially contaminated surface soils in and around Area of Concern (AOC) 492 at the Paducah Gaseous Diffusion Plant (PGDP). The work was conducted under the auspices of Kentucky Research Consortium for Energy and Environment (KRCEE). KRCEE was created to support the Department of Energy's (DOE) efforts to complete the expeditious and economically viable environmental restoration of the Paducah Gaseous Diffusion Plant (PGDP), the Western Kentucky Wildlife Management Area (WKWMA), and surrounding areas.

  12. New technology for interactive CAL: the Origami project

    Directory of Open Access Journals (Sweden)

    Robert Harding

    1997-12-01

    Full Text Available For many years, almost since the dawn of computing, people have speculated about the paperless society. Each new technology is heralded as the one that will finally take us to the fully electronic Utopia. However, the use of computers as document preparation tools has actually increased the number of paper documents. The latest mass-market development, the Internet, is unlikely to buck this trend even though the tools used seem to encourage on-screen browsing. The problems inherent with screen presentation have not gone away, while the amount of information available to the average computer user is increasing all the time.

  13. Cooperation, Technology, and Performance: A Case Study.

    Science.gov (United States)

    Cavanagh, Thomas; Dickenson, Sabrina; Brandt, Suzanne

    1999-01-01

    Describes the CTP (Cooperation, Technology, and Performance) model and explains how it is used by the Department of Veterans Affairs-Veteran's Benefit Administration (VBA) for training. Discusses task analysis; computer-based training; cooperative-based learning environments; technology-based learning; performance-assessment methods; courseware…

  14. Northwest Open Automated Demand Response Technology Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccote, Sila; Piette, Mary Ann; Dudley, Junqiao

    2010-03-17

    The Lawrence Berkeley National Laboratory (LBNL) Demand Response Research Center (DRRC) demonstrated and evaluated open automated demand response (OpenADR) communication infrastructure to reduce winter morning and summer afternoon peak electricity demand in commercial buildings the Seattle area. LBNL performed this demonstration for the Bonneville Power Administration (BPA) in the Seattle City Light (SCL) service territory at five sites: Seattle Municipal Tower, Seattle University, McKinstry, and two Target stores. This report describes the process and results of the demonstration. OpenADR is an information exchange model that uses a client-server architecture to automate demand-response (DR) programs. These field tests evaluated the feasibility of deploying fully automated DR during both winter and summer peak periods. DR savings were evaluated for several building systems and control strategies. This project studied DR during hot summer afternoons and cold winter mornings, both periods when electricity demand is typically high. This is the DRRC project team's first experience using automation for year-round DR resources and evaluating the flexibility of commercial buildings end-use loads to participate in DR in dual-peaking climates. The lessons learned contribute to understanding end-use loads that are suitable for dispatch at different times of the year. The project was funded by BPA and SCL. BPA is a U.S. Department of Energy agency headquartered in Portland, Oregon and serving the Pacific Northwest. BPA operates an electricity transmission system and markets wholesale electrical power at cost from federal dams, one non-federal nuclear plant, and other non-federal hydroelectric and wind energy generation facilities. Created by the citizens of Seattle in 1902, SCL is the second-largest municipal utility in America. SCL purchases approximately 40% of its electricity and the majority of its transmission from BPA through a preference contract. SCL also

  15. Cost Savings Analysis Guidelines for Manufacturing Technology Projects.

    Science.gov (United States)

    1985-06-28

    14 3.2.1 ’CHANGED COSTO SAMPLE PROJECT .................. .. 16 3.2.1.1 COST SAVINGS NARRATIVE ..................... 17 3.2.1.2 RECURRING COSTS...the Level II refurbishment techniques, develop additional Level III regrinding techniques, and produce a generic manual on bearing rework procedures...40 c L0 4) 10 4) ) 4-0 4 0C A 0~~ 0 10 4C C 4) I L.~1 0 f ) AU 1 .01 4S *~~C P;ir L 0I. 0 4) - 0 0IC C I-.C*12 IA Iii 0 0 0~~~ N b>v> *w .0 o a ab2 0

  16. Project Responder: technology needs for local emergency response

    Science.gov (United States)

    Beakley, Guy; Garwin, Thomas; Pollard, Neal A.; Singley, George T., III; Tuohy, Robert V.; Lupo, Jasper

    2003-09-01

    Since April 2001, the Oklahoma City National Memorial Institute for the Prevention of Terrorism has funded an effort by Hicks &Associates, Inc. and the Terrorism Research Center, Inc., aimed ultimately at improving local, state, and federal emergency responders" capabilities for mitigating the effects of chemical, biological, radiological, nuclear or explosive/ incendiary (CBRNE) terrorism. This effort, titled "Project Responder," began by developing an understanding of how state and local responders view their current capabilities, shortfalls, and needs. This paper discusses some of the results of this first phase of the effort that has resulted in a comprehensive report titled "Emergency Responders" Needs, Goals, and Priorities." This paper addresses two of the capabilities from that report which we believe are of most interest to this conference. There are ten other capabilities discussed in the report, which may also be of interest.

  17. Manual on SFR R and D and Technology Monitoring System Based on Enterprise Project Management Solution

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Uk; Lee, Yong Bum; Won, Byung Chool; Kim, Young In; Hahn, Do Hee

    2008-04-15

    This report is a manual on enterprise project management solution for R and D and technology monitoring system that is applicable for managing the generation IV sodium-cooled fast reactor development. The prime goal of this system is to provide project manager with reliable and accurate information of status of progress, performance and resource allocation, and attain traceability and visibility of project implementation for effective project management. This report is composed of the three part. The first part is an introduction on microsoft project professional software that was used to monitor the progress, evaluate the results and analyze the resource distribution of the activities. The second makes a description of project plan and control, and the third part describes on collaboration and teamwork.

  18. A framework for identifying the applicability of heating or cooling technologies based on initial project information

    Science.gov (United States)

    Cacace, Katie Meng

    In order to fully achieve the energy savings and human comfort benefits of many alternative heating and cooling technologies, design considerations for these technologies must be made during the conceptual design stage. However, at this stage architects are often faced with challenges that inhibit the integration of such technologies. At the early stages of design, architects have limited time and technical knowledge to research alternative technologies and mechanical engineers are typically not yet part of the design team to offer their expertise. To address these problems, this research developed a framework for a Technology Identifier that would inform an architect about alternative heating and cooling technologies that are applicable to their specific project at the conceptual design stage. The framework is based on the premise that a quantitative relationship between the initial project information and a technology's critical output variable(s) for heat transfer to the space can be established. Therefore, to be included in the framework a technology must possess a component that provides direct heat transfer to the space for the framework to determine if the technology can maintain the desired space temperature. The climatic influences on a technology's performance and the effect of changing a technology's input variables on the heat transfer output variable(s) were also quantified. Existing building energy simulation programs were used in these analyses. The framework develops simulation input files for multiple technologies, utilizes existing simulation programs to predict the performance of these technologies, and then displays the output results along with other information that is useful to designers at the conceptual stage. Each simulation input file is compiled from a template that queries databases and requires minimal user input. The output display includes the space temperature, energy consumption, and design considerations of each technology. A

  19. Decontamination Technologies, Task 3, Urban Remediation and Response Project

    Energy Technology Data Exchange (ETDEWEB)

    Heiser,J.; Sullivan, T.

    2009-06-30

    In the aftermath of a Radiological Dispersal Device (RDD, also known as a dirty bomb) it will be necessary to remediate the site including building exteriors and interiors, equipment, pavement, vehicles, personal items etc. Remediation will remove or reduce radioactive contamination from the area using a combination of removing and disposing of many assets (including possible demolition of buildings), decontaminating and returning to service other assets, and fixing in place or leaving in place contamination that is deemed 'acceptable'. The later will require setting acceptable dose standards, which will require negotiation with all involved parties and a balance of risk and cost to benefit. To accomplish the first two, disposal or decontamination, a combination of technologies will be deployed that can be loosely classified as: Decontamination; Equipment removal and size reduction; and Demolition. This report will deal only with the decontamination technologies that will be used to return assets to service or to reduce waste disposal. It will not discuss demolition, size reduction or removal technologies or equipment (e.g., backhoe mounted rams, rock splitter, paving breakers and chipping hammers, etc.). As defined by the DOE (1994), decontamination is removal of radiological contamination from the surfaces of facilities and equipment. Expertise in this field comes primarily from the operation and decommissioning of DOE and commercial nuclear facilities as well as a small amount of ongoing research and development closely related to RDD decontamination. Information related to decontamination of fields, buildings, and public spaces resulting from the Goiania and Chernobyl incidents were also reviewed and provide some meaningful insight into decontamination at major urban areas. In order to proceed with decontamination, the item being processed needs to have an intrinsic value that exceeds the cost of the cleaning and justifies the exposure of any workers

  20. Technology transfer significance of the International Safeguards Project Office

    Energy Technology Data Exchange (ETDEWEB)

    Marcuse, W.; Waligura, A.J.

    1988-06-01

    The safeguards implemented by the International Atomic Energy Agency (IAEA) are of major importance to the non-proliferation objectives of the United States of America and other nations of the world. Assurance of safeguards effectiveness is mandatory to continued peaceful use of nuclear power. To enhance the ability of the IAEA to apply safeguards effectively, and to ensure that the IAEA does not lack technical assistance in critical areas, the US Congress has made available a special authorization for a Program for Technical Assistance to IAEA Safeguards (POTAS). This substantial program of technology transfer was initiated in 1976. The United States Departments of State and Energy, the Arms control and Disarmament Agency and the Nuclear Regulatory Commission have each accepted responsibility for parts of the Program for Technical Assistance to IAEA Safeguards. Funding is provided by state through the Foreign Assistance Act. This report provides a discussion of this program.

  1. Information Technology in project-organized electronic and computer technology engineering education

    DEFF Research Database (Denmark)

    Nielsen, Kirsten Mølgaard; Nielsen, Jens Frederik Dalsgaard

    1999-01-01

    This paper describes the integration of IT in the education of electronic and computer technology engineers at Institute of Electronic Systems, Aalborg Uni-versity, Denmark. At the Institute Information Technology is an important tool in the aspects of the education as well as for communication...

  2. A Report on the Technological Enhancements Project Evaluation: Deepening Early Learning Experiences through Technology

    Science.gov (United States)

    Hupert, Naomi; Cervantes, Francisco; DeGroof, Emily

    2010-01-01

    As part of the "Ready to Learn" Initiative, Education Development Center, Inc. (EDC), was charged with addressing the evaluation of Technological Enhancements for the outreach efforts of three producers: Out of the Blue's Super WHY! Technology Add-On; Sesame Workshop's The Electric Company School's Initiative Curriculum; and WordWorld's eBook…

  3. Applications of EOR (enhanced oil recovery) technology in field projects--1990 update

    Energy Technology Data Exchange (ETDEWEB)

    Pautz, J.F.; Thomas, R.D.

    1991-01-01

    Trends in the type and number of US enhanced oil recovery (EOR) projects are analyzed for the period from 1980 through 1989. The analysis is based on current literature and news media and the Department of Energy (DOE) EOR Project Data Base, which contains information on over 1,348 projects. The characteristics of the EOR projects are grouped by starting date and process type to identify trends in reservoir statistics and applications of process technologies. Twenty-two EOR projects starts were identified for 1989 and ten project starts for 1988. An obvious trend over recent years has been the decline in the number of project starts since 1981 until 1988 which corresponds to the oil price decline during that period. There was a modest recovery in 1989 of project starts, which lags the modest recovery of oil prices in 1987 that was reconfirmed in 1989. During the time frame of 1980 to 1989, there has been a gradual improvement in costs of operation for EOR technology. The perceived average cost of EOR has gone down from a $30/bbl range to low $20/bbl. These costs of operation seems to stay just at the price of oil or slightly above to result in marginal profitability. The use of polymer flooding has drastically decreased both in actual and relative numbers of project starts since the oil price drop in 1986. Production from polymer flooding is down more than 50%. Long-term plans for large, high-cost projects such as CO{sub 2} flooding in West Texas, steamflooding in California, and hydrocarbon flooding on the North Slope have continued to be implemented. EOR process technologies have been refined to be more cost effective as shown by the continued application and rising production attributable to EOR. 8 refs., 6 figs., 13 tabs.

  4. Planning and leading of the technological processes by mechanical working with microsoft project

    Science.gov (United States)

    Nae, I.; Grigore, N.

    2016-08-01

    Nowadays, fabrication systems and methods are being modified; new processing technologies come up, flow sheets develop a minimum number of phases, the flexibility of the technologies grows up, new methods and instruments of monitoring and leading the processing operations also come up. The technological course (route, entry, scheme, guiding) referring to the series of the operation, putting and execution phases of a mark in order to obtain the final product from the blank is represented by a sequence of activities realized by a logic manner, on a well determined schedule, with a determined budget and resources. Also, a project can be defined as a series of specific activities, methodical structured which they aim to finish a specific objective, within a fixed schedule and budget. Within the homogeneity between the project and the technological course, this research is presenting the defining of the technological course of mechanical chip removing process using Microsoft Project. Under these circumstances, this research highlights the advantages of this method: the celerity using of other technological alternatives in order to pick the optimal process, the job scheduling being constrained by any kinds, the standardization of some processing technological operations.

  5. Fire-Protection Research for Energy-Technology Projects: FY 1981 year-end report

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, H.K.; Alvares, N.J.; Lipska-Quinn, A.E.; Beason, D.G.; Foote, K.L.; Priante, S.J.

    1982-07-20

    This report summarizes research conducted in fiscal year 1981 for the DOE-supported project, Fire Protection Research for Energy Technology Projects. Initiated in 1977, this ongoing research program was conceived to advance fire protection strategies for Energy Technology Projects to keep abreast of the unique fire problems that are developing with the complexity of energy technology research. We are developing an analytical methodology through detailed study of fusion energy experiments at Lawrence Livermore National Laboratory (LLNL). Employing these facilities as models for methodology development, we are simultaneously advancing three major task areas: (1) determination of unique fire hazards of current fusion energy facilities; (2) evaluation of the ability of accepted fire management measures to meet and negate hazards; and (3) performance of unique research into problem areas we have identified to provide input into analytical fire-growth and damage-assessment models.

  6. The 2011 nuclear medicine technology job analysis project of the American Registry of Radiologic Technologists.

    Science.gov (United States)

    Anderson, Dan; Hubble, William; Press, Bret A; Hall, Scott K; Michels, Ann D; Koenen, Roxanne; Vespie, Alan W

    2010-12-01

    The American Registry of Radiologic Technologists (ARRT) conducts periodic job analysis projects to update the content and eligibility requirements for all certification examinations. In 2009, the ARRT conducted a comprehensive job analysis project to update the content specifications and clinical competency requirements for the nuclear medicine technology examination. ARRT staff and a committee of volunteer nuclear medicine technologists designed a job analysis survey that was sent to a random sample of 1,000 entry-level staff nuclear medicine technologists. Through analysis of the survey data and judgments of the committee, the project resulted in changes to the nuclear medicine technology examination task list, content specifications, and clinical competency requirements. The primary changes inspired by the project were the introduction of CT content to the examination and the expansion of the content covering cardiac procedures.

  7. Technology Integration in the LHC EXperiments Joint Controls Project

    Institute of Scientific and Technical Information of China (English)

    R.Barillere; M.Beharrell; 等

    2001-01-01

    The development and maintenance of the control systems of the four LHC experiments will require a non-negligible amount of resources and effort.The Joint Controls Project(JCOP)[1] has been set-up as a collaboration between CERN and the four LHC experiments to find common solutions for the LHC experiments' control systems.Although the JCOP general principle is to promote the use of industrial ssoluitions wherever possible,custom solutions are still required when non-standard devices or very large numbers of devices have to be controlled.Furthermore.to ease the development and integration of both standard and non-standard devices into the control system a number of software Frameworks are under development.This paper will describe the various solutions being proposed by JCOP including the Supervisory and Front-End frameworks as well as the various industrial and custom components.In addition,It will also describe where these fit into the foreseen JCOP controls architecture.The paper will then highlight in more detail the Front-End Framework.

  8. Modeling Projects in E-Learning Course: A Case of an Information Technology Project

    Directory of Open Access Journals (Sweden)

    Mohammed G. Belkasmi

    2010-01-01

    Full Text Available Problem statement: Achieving projects is primordial in the process of teaching in several disciplines, particularly software engineering courses. However, proposing this learning activity in a context of e-learning is not automatically guaranteed by the current platforms, even unsupported by the existing standards for creating educational content. Approach: Through this study, starting from the model developed in the “XESOP-Jaxe” project to represent the contents of an e-learning course, we tried to propose an improvement in order to formalize a project for learners as a learning object. Results: We grafted our model, formalized in XML Schema, to the “XESOP-Jaxe” schema of the course. Thus, to the elements that could constitute a course, comes a new element called “projet” (project. Conclusion: This model was built and tested within the “XESOP-Jaxe” platform whose goal is to provide an effective solution for creating educational content in compliance with existing standards.

  9. WEB 2.0 SERVICES AS A TECHNOLOGICAL FOUNDATION OF A NETWORK PROJECT

    Directory of Open Access Journals (Sweden)

    Tatiana Ivanovna Kanyanina

    2015-02-01

    Full Text Available In the light of the requirements of the federal state educational standard increases the value of the network design based on the use of Web 2.0 services. The article outlines the range of technological challenges faced by the developer of the network project, such as the choice of the network platform of the project, design tools and tools for project results placement, project coordination and organization of communication lines, the choice of instruments for the promotion of the project on the Internet. The main attention is focused on the examples of network services that address these challenges, and describe their features. The authors rely on the specific network projects implemented in Nizhny Novgorod region. The paper analyzes the possible project’s network sites (network environment. The article gives a general description of each environment, marks its distinctive features, advantages and disadvantages. The article presents project tasks’ examples, designed on the basis of the variety of Web 2.0 services that functionally meet the requirements of a particular task, examples of services to represent the project products and to summarize its results. Attention is paid to the organization of the lines of communication of the project participants and organizers and to the role of network services in the project promotion on the Internet.

  10. A Proposal to Manage Lessons Learned in Projects: Web 2.0 Technologies to Promote Innovation

    OpenAIRE

    Marcirio Silveira Chaves.; Giuliana Santos Veronese

    2014-01-01

    The web 2.0 is transforming the project management in organizations by improving communication and collaboration. The new generation of web-based collaborative tools provides much better experience than the traditional software package allowing document sharing, integrated task tracking, enforcing team processes and agile planning. Despite of the indubitable benefits brought by web 2.0, the use of these technologies to promote knowledge management remains unexplored. For many project managers...

  11. TANK FARM REMEDIATION TECHNOLOGY DEVELOPMENT PROJECT AN EXERCISE IN TECHNICAL & REGULATORY COLLABORATION

    Energy Technology Data Exchange (ETDEWEB)

    JARAYSI, M.N.

    2007-01-08

    The Tank Farm Remediation Technology Development Project at the Hanford Site focuses on waste storage tanks, pipelines and associated ancillary equipment that are part of the C-200 single-shell tank (SST) farm system located in the C Tank Farm. The purpose of the project is to obtain information on the implementation of a variety of closure activities and to answer questions on technical, operational and regulatory issues associated with closure.

  12. Application of the Exergy UCG technology in international UCG projects

    Science.gov (United States)

    Blinderman, M. S.

    2017-07-01

    Underground Coal Gasification is a subject of continuing global interest in the energy sector. While the international scenario in UCG is promising, it is deeply desirable that advances in this area are seen in India as well. This is particularly so with the Paris Climate Agreement bringing in more stringent challenges for clean energy development. India has many potential coal basins which may be suitable for UCG deployment. India is in dire need of indigenous source of gaseous and liquid hydrocarbons that could compete with imported products. It is also the country with exceptionally large and diverse coal and lignite resources, large part of which could not be mined due to geological complexity and prohibitive cost. Thus, there is a rationale that the εUCG™ technology plays a decisive role in realizing the potential of Indian coal resources for the benefit of Indian industry and population. This article has been adapted by Dr. Ajay K. Singh from a lecture delivered at the “Workshop on Challenges and Opportunities of Underground Coal Gasification”, Vigyan Bhawan, New Delhi on 14 February 2017.

  13. Using technology-enhanced, cooperative, group-project learning for student comprehension and academic performance

    Science.gov (United States)

    Tlhoaele, Malefyane; Suhre, Cor; Hofman, Adriaan

    2016-05-01

    Cooperative learning may improve students' motivation, understanding of course concepts, and academic performance. This study therefore enhanced a cooperative, group-project learning technique with technology resources to determine whether doing so improved students' deep learning and performance. A sample of 118 engineering students, randomly divided into two groups, participated in this study and provided data through questionnaires issued before and after the experiment. The results, obtained through analyses of variance and structural equation modelling, reveal that technology-enhanced, cooperative, group-project learning improves students' comprehension and academic performance.

  14. Use of communication technologies in document exchange for the management of construction projects

    Directory of Open Access Journals (Sweden)

    Mesároš Peter

    2016-06-01

    Full Text Available Information and communication technologies represent a set of people, processes, technical and software tools providing collection, transport, storage and processing of data for distribution and presentation of information. Particularly communication systems are the main tool for information exchange. Of the other part, these technologies have a broad focus and use. One of them is the exchange of documents in the management of construction projects. Paper discusses the issue of exploitation level of communication technologies in construction project management. The main objective of this paper is to analyze exploitation level of communication technologies. Another aim of the paper is to compare exploitation level or rate of document exchange by electronic communication devices and face-to-face communication.

  15. Use of communication technologies in document exchange for the management of construction projects

    Science.gov (United States)

    Mesároš, Peter; Mandičák, Tomáš

    2016-06-01

    Information and communication technologies represent a set of people, processes, technical and software tools providing collection, transport, storage and processing of data for distribution and presentation of information. Particularly communication systems are the main tool for information exchange. Of the other part, these technologies have a broad focus and use. One of them is the exchange of documents in the management of construction projects. Paper discusses the issue of exploitation level of communication technologies in construction project management. The main objective of this paper is to analyze exploitation level of communication technologies. Another aim of the paper is to compare exploitation level or rate of document exchange by electronic communication devices and face-to-face communication.

  16. Expansion of Michigan EOR Operations Using Advanced Amine Technology at a 600 MW Project Wolverine Carbon Capture and Storage Project

    Energy Technology Data Exchange (ETDEWEB)

    H Hoffman; Y kishinevsky; S. Wu; R. Pardini; E. Tripp; D. Barnes

    2010-06-16

    Wolverine Power Supply Cooperative Inc, a member owned cooperative utility based in Cadillac Michigan, proposes to demonstrate the capture, beneficial utilization and storage of CO{sub 2} in the expansion of existing Enhanced Oil Recovery operations. This project is being proposed in response to the US Department of Energy Solicitation DE-FOA-0000015 Section III D, 'Large Scale Industrial CCS projects from Industrial Sources' Technology Area 1. The project will remove 1,000 metric tons per day of CO{sub 2} from the Wolverine Clean Energy Venture 600 MW CFB power plant owned and operated by WPC. CO{sub 2} from the flue gas will be captured using Hitachi's CO{sub 2} capture system and advanced amine technology. The capture system with the advanced amine-based solvent supplied by Hitachi is expected to significantly reduce the cost and energy requirements of CO{sub 2} capture compared to current technologies. The captured CO{sub 2} will be compressed and transported for Enhanced Oil Recovery and CO{sub 2} storage purposes. Enhanced Oil Recovery is a proven concept, widely used to recover otherwise inaccessible petroleum reserves. While post-combustion CO{sub 2} capture technologies have been tested at the pilot scale on coal power plant flue gas, they have not yet been demonstrated at a commercial scale and integrated with EOR and storage operations. Amine-based CO{sub 2} capture is the leading technology expected to be available commercially within this decade to enable CCS for utility and industrial facilities firing coal and waste fuels such as petroleum coke. However, traditional CO{sub 2} capture process utilizing commercial amine solvents is very energy intensive for regeneration and is also susceptible to solvent degradation by oxygen as well as SOx and NO{sub 2} in the flue gas, resulting in large operating costs. The large volume of combustion flue gas with its low CO{sub 2} concentration requires large equipment sizes, which together with the

  17. The Application of Persuasive Technology to educational settings: Some theoretical from the HANDS Project

    DEFF Research Database (Denmark)

    Mintz, Joseph; Aagaard, Morten

    2010-01-01

    In the HANDS project Persuasive Technology is applied in an educational context in special schools for children with autism, in which social skills development is the aim of the persuasion. We consider how in such educational settings the interventions can be theorized in the context of existing...... educational paradigms. We discuss the relation between such paradigms and persuasive technology, and the specific case of persuasion in the pedagogical context of children with autism....

  18. Update on the SKA Offset Optics Design for the U.S. Technology Development Project

    Science.gov (United States)

    Imbriale, William A.; Cortes-Medellin, German; Baker, Lynn

    2011-01-01

    The U.S. design concept for the Square Kilometre Array (SKA) program is based on utilizing a large number of small-diameter dish antennas in the 12 to 15 meter diameter range. The Technology Development Project (TDP) is planning to design and build the first of these antennas to provide a demonstration of the technology and a solid base on which to estimate costs. The latest considerations for selecting both the optics and feed design are presented.

  19. Synthesis about a collaborative project on “Technology Assessment of Autonomous Systems”

    OpenAIRE

    António B. Moniz

    2009-01-01

    The project started in 2009 with the support of DAAD in Germany and CRUP in Portugal under the “Collaborative German-Portuguese University Actions” programme. One central goal is the further development of a theory of technology assessment applied to robotics and autonomous systems in general that reflects in its methodology the changing conditions of knowledge production in modern societies and the emergence of new robotic technologies and of associated disruptive changes. Relevant topics he...

  20. Residential Energy Efficiency Demonstration: Hawaii and Guam Energy Improvement Technology Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L.; Sparn, B.; Rutter, A.; Briggs, D.

    2014-03-01

    In order to meet its energy goals, the Department of Defense (DOD) has partnered with the Department of Energy (DOE) to rapidly demonstrate and deploy cost-effective renewable energy and energy-efficiency technologies. The scope of this project was to demonstrate tools and technologies to reduce energy use in military housing, with particular emphasis on measuring and reducing loads related to consumer electronics (commonly referred to as 'plug loads'), hot water, and whole-house cooling.

  1. Computer Technology-Integrated Projects Should Not Supplant Craft Projects in Science Education

    Science.gov (United States)

    Klopp, Tabatha J.; Rule, Audrey C.; Schneider, Jean Suchsland; Boody, Robert M.

    2014-01-01

    The current emphasis on computer technology integration and narrowing of the curriculum has displaced arts and crafts. However, the hands-on, concrete nature of craft work in science modeling enables students to understand difficult concepts and to be engaged and motivated while learning spatial, logical, and sequential thinking skills. Analogy…

  2. Computer Technology-Integrated Projects Should not Supplant Craft Projects in Science Education

    Science.gov (United States)

    Klopp, Tabatha J.; Rule, Audrey C.; Suchsland Schneider, Jean; Boody, Robert M.

    2014-03-01

    The current emphasis on computer technology integration and narrowing of the curriculum has displaced arts and crafts. However, the hands-on, concrete nature of craft work in science modeling enables students to understand difficult concepts and to be engaged and motivated while learning spatial, logical, and sequential thinking skills. Analogy use is also helpful in understanding unfamiliar, complex science concepts. This study of 28 academically advanced elementary to middle-school students examined student work and perceptions during a science unit focused on four fossil organisms: crinoid, brachiopod, horn coral and trilobite. The study compared: (1) analogy-focused instruction to independent Internet research and (2) computer technology-rich products to crafts-based products. Findings indicate student products were more creative after analogy-based instruction and when made using technology. However, students expressed a strong desire to engage in additional craft work after making craft products and enjoyed making crafts more after analogy-focused instruction. Additionally, more science content was found in the craft products than the technology-rich products. Students expressed a particular liking for two of the fossil organisms because they had been modeled with crafts. The authors recommend that room should be retained for crafts in the science curriculum to model science concepts.

  3. Improvement of CTP Routing Algorithm Based on WSN Balanced Collection Tree%基于WSN均衡汇聚树的CTP路由算法改进

    Institute of Scientific and Technical Information of China (English)

    赵晨旭; 吴怡之; 韩汉光

    2012-01-01

    针对无线传感器网络(WSN)节点能量均衡消耗的需求,提出一种基于均衡汇聚树的路由算法LB-CTP.该算法定义节点均衡度,引入规避繁忙节点接入机制.在路由更新中,相应节点以LB-CTP路由算法选择父节点接入网络,分担繁忙节点负担.基于TinyOS操作系统对LB-CTP进行实现,通过TOSSIM平台进行仿真实验,结果表明,与CTP算法相比,LB-CTP算法能有效地均衡网络负载.%To meet the requirement of energy consumption balance between nodes of Wireless Sensor NetworksfWSN), an unproved Collection Tree routing Protocol(CTP) based on complete-balanced collection tree, called LB-CTP, is proposed, in which node balance level and busy node access avoidance mechanisms are defined. In order to share the burden of the busy node, the related node access to network according to LB-CTP routing algorithm in the routing setup stage. To evaluate the algorithm, the LB-CTP is implemented on the TinyOS and runs on TOSSIM simulation platform. Results show that LB-CTP can balance network load of WSN more effectively compared with CTP.

  4. ESA's Cloudscape: A Review of Projects Using Cloud Technology in ESA

    Science.gov (United States)

    O'Mullane, W.; Balseiro, J. F.

    2012-09-01

    Several projects in the space agency have flirted with cloud solutions, all with fairly positive results. In this talk a quick overview of the projects will be given. They span a large number of perhaps surprising areas. Much of ESA's videoconferencing is now done using cloud resources. Perhaps more than one might expect, several projects from earth observation to astronomy use cloud tech for data processing. Some more detail will be given from the Gaia perspective, as this is the authors' area of expertise. Within Gaia we have experimented with Amazon for data processing and are investigating how catalogue access might be facilitated with this technology.

  5. Synthesizing R&D Data: Experiences from the Integrated Manufacturing Technology Roadmap (IMTR) Project

    Energy Technology Data Exchange (ETDEWEB)

    merrell, m.a.

    1999-05-05

    IMTR is a tremendous undertaking to assess the current state and future needs of Manufacturing Technology R&D. A follow-on project to the roadmaps is the development and populating of a Gap Analysis database containing current R&D abstracts related to the roadmaps' technical elements. Efficiently identifying the R&D projects within scope presents many travails of synthesizing data from across a wide spectrum. Challenges to this project were directly proportional to the lack of single-source data collections.

  6. Projects from Federal Region IX: Department of Energy Appropriate Energy Technology Program. Part II

    Energy Technology Data Exchange (ETDEWEB)

    Case, C.W.; Clark, H.R.; Kay, J.; Lucarelli, F.B.; Rizer, S.

    1980-01-01

    Details and progress of appropriate energy technology programs in Region IX are presented. In Arizona, the projects are Solar Hot Water for the Prescott Adult Center and Solar Prototype House for a Residential Community. In California, the projects are Solar AquaDome Demonstration Project; Solar Powered Liquid Circulating Pump; Appropriate Energy Technology Resource Center; Digester for Wastewater Grown Aquatic Plants; Performance Characteristics of an Anaerobic Wastewater Lagoon Primary Treatment System; Appropriate Energy/Energy Conservation Demonstration Project; Solar Energy for Composting Toilets; Dry Creek Rancheria Solar Demonstration Projects; Demonstration for Energy Retrofit Analysis and Implementation; and Active Solar Space Heating System for the Integral Urban House. In Hawaii, the projects are: Java Plum Electric; Low-Cost Pond Digesters for Hawaiian Pig Farm Energy Needs; Solar Beeswax Melter; Methane Gas Plant for Operating Boilers and Generating Steam; and Solar Water Heating in Sugarcane Seed-Treatment Plants. A Wind-Powered Lighted Navigation Buoys Project for Guam is also described. A revised description of the Biogas Energy for Hawaiian Small Farms and Homesteads is given in an appendix.

  7. Project-Driven Learning-by-Doing Method for Teaching Software Engineering using Virtualization Technology

    Directory of Open Access Journals (Sweden)

    Kun Ma

    2014-10-01

    Full Text Available Many universities are now offering software engineering an undergraduate level emphasizing knowledge point. However, some enterprise managers reflected that education ignore hands-on ability training, and claimed that there is the isolation between teaching and practice. This paper presents the design of a Software Engineering course (sixth semester in network engineering at University of Jinan for undergraduate Software Engineering students that uses virtualization technology to teach them project-driven learning-by-doing software development process. We present our motivation, challenges encountered, pedagogical goals and approaches, findings (both positive experiences and negative lessons. Our motivation was to teach project-driven Software Engineering using virtualization technology. The course also aims to develop entrepreneurial skills needed for software engineering graduates to better prepare them for the software industry. Billing models of virtualization help pupils and instructors find the cost of the experiment. In pay-as-you-go manner, two labs and three step-by-step projects (single project, pair project, and team project are designed to help the students to complete the assignment excitedly. We conduct some detailed surveys and present the results of student responses. The assessment process designed for this course is illustrated. The paper also shows that learning-by-doing method correlates with the characteristics of different projects, which has resulted in a successful experience as reported by students in an end of a semester survey.

  8. Investments in information systems and technology in the healthcare: Project management mediation

    Directory of Open Access Journals (Sweden)

    Jorge Gomes

    2017-03-01

    Full Text Available Healthcare organisations must improve their business practices and internal procedures in order to answer the increasing demand of health professionals and the general public for more and better information. Hospitals invest massively in information systems and technology (IS/IT in the hope that these investments will improve healthcare and meet patients’ demands. The main objective of our research is to study how organisational maturity, enhanced by investments in IS/IT, project management and best practices, leads to successful projects in public healthcare organisations. The rational of our model is that organisational maturity has a positive effect on IS/IT project success, and that this success is also positively enhanced by the use of project management practices. We emphasise that this combination of approaches can increase the effectiveness of projects. Furthermore, it can also improve the confidence that the results of investments will meet stakeholders’ expectations.

  9. INTEGRATING GEOSPATIAL TECHNOLOGIES AND SECONDARY STUDENT PROJECTS: THE GEOSPATIAL SEMESTER

    Directory of Open Access Journals (Sweden)

    Bob Kolvoord

    2012-12-01

    Full Text Available Resumen:El Semestre Geoespacial es una actividad de educación geográfica centrada en que los estudiantes del último curso de secundaria en los institutos norteamericanos, adquieran competencias y habilidades específicas en sistemas de información geográfica, GPS y teledetección. A través de una metodología de aprendizaje basado en proyectos, los alumnos se motivan e implican en la realización de trabajos de investigación en los que analizan, e incluso proponen soluciones, diferentes procesos, problemas o cuestiones de naturaleza espacial. El proyecto está coordinado por la Universidad James Madison y lleva siete años implantándose en diferentes institutos del Estado de Virginia, implicando a más de 20 centros educativos y 1.500 alumnos. Los alumnos que superan esta asignatura de la enseñanza secundaria obtienen la convalidación de determinados créditos académicos de la Universidad de referencia.Palabras clave:Sistemas de información geográfica, enseñanza, didáctica de la geografía, semestre geoespacial.Abstract:The Geospatial Semester is a geographical education activity focused on students in their final year of secondary schools in the U.S., acquiring specific skills in GIS, GPS and remote sensing. Through a methodology for project-based learning, students are motivated and involved in conducting research using geographic information systems and analyze, and even propose solutions, different processes, problems or issues spatial in nature. The Geospatial Semester university management not only ensures proper coaching, guidance and GIS training for teachers of colleges, but has established a system whereby students who pass this course of secondary education gain the recognition of certain credits from the University.Key words:Geographic information system, teaching, geographic education, geospatial semester. Résumé:Le semestre géospatial est une activité axée sur l'éducation géographique des étudiants en derni

  10. Ceramic Technology Project, semiannual progress report for October 1993 through March 1994

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.R.

    1994-09-01

    The Ceramic Technology Project was originally developed by the Department of Energy`s Office of Transportation Systems (OTS) in Conservation and Renewable Energy. Significant accomplishments in fabricating ceramic components for the Department of Energy (DOE), National Aeronautics and Space Administration (NASA), and Department of Defense (DoD) advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. An assessment of needs was completed, and a five-year project plan was developed with extensive input from private industry. In July 1990, the original plan was updated through the estimated completion of development in 1993. The original objective of the project was to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. During the course of the Ceramic Technology Project, remarkable progress has been made in the development of reliable structural ceramics. The direction of the Ceramic Technology Project is now shifting toward reducing the cost of ceramics to facilitate commercial introduction of ceramic components for near-term engine applications. In response to extensive input from industry, the plan is to extend the engine types which were previously supported (advanced gas turbine and low-heat-rejection diesel engines) to include near-term (5-10 years) applications in conventional automobile and diesel truck engines. To facilitate the rapid transfer of this technology to U.S. industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities. A systematic approach to reducing the cost of components is envisioned.

  11. Bilişim Teknolojisi Projelerinde Reel Opsiyonlar (Real Options in Information Technology Projects

    Directory of Open Access Journals (Sweden)

    İpek Deveci KOCAKOÇ

    2009-10-01

    Full Text Available Many sources such as the immaturity, complexity and unpredictable evolution of the technologies themselves, and the difficulty of predicting the market demand generally cause uncertainty in the Information Technology (IT projects. Managerial flexibility has value in the context of uncertain IT projects, as management can continuously gather information about uncertain project and market characteristics and, based on this information, change its course of action. As traditional capital budgeting (or project appraisal approaches fail to consider embedded managerial flexibility in projects, the new investment evaluation approach called “real options” has come on the scene recently. “Options thinking,” an emerging investment management philosophy based on the theory of financial options can provide a promising foundation for hedging the risks under uncertainty. This paper aims at analyzing a real IT investment having growth opportunities by using real options approach. Specifically, the value of investing in a software project as well as embedded flexibility in this opportunity is modeled as an option contract. The expected costs required for completing the project and thereafter the resulting asset value are considered as the base-case parameters of this contract. Option values derived from Binomial method are used for evaluating the project and the optimal investment policy is determined based on these values. As a result, it is shown that the value of an IT project having flexibility can differ from one obtained with traditional capital budgeting methods and a rejected project which was seen as unprofitable before can turn a profitable one through embedded flexibilities.

  12. Pacific Northwest Smart Grid Demonstration Project Technology Performance Report Volume 1: Technology Performance

    Energy Technology Data Exchange (ETDEWEB)

    Melton, Ron [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-01

    The Pacific Northwest Smart Grid Demonstration (PNWSGD), a $179 million project that was co-funded by the U.S. Department of Energy (DOE) in late 2009, was one of the largest and most comprehensive demonstrations of electricity grid modernization ever completed. The project was one of 16 regional smart grid demonstrations funded by the American Recovery and Reinvestment Act. It was the only demonstration that included multiple states and cooperation from multiple electric utilities, including rural electric co-ops, investor-owned, municipal, and other public utilities. No fewer than 55 unique instantiations of distinct smart grid systems were demonstrated at the projects’ sites. The local objectives for these systems included improved reliability, energy conservation, improved efficiency, and demand responsiveness. The demonstration developed and deployed an innovative transactive system, unique in the world, that coordinated many of the project’s distributed energy resources and demand-responsive components. With the transactive system, additional regional objectives were also addressed, including the mitigation of renewable energy intermittency and the flattening of system load. Using the transactive system, the project coordinated a regional response across the 11 utilities. This region-wide connection from the transmission system down to individual premises equipment was one of the major successes of the project. The project showed that this can be done and assets at the end points can respond dynamically on a wide scale. In principle, a transactive system of this type might eventually help coordinate electricity supply, transmission, distribution, and end uses by distributing mostly automated control responsibilities among the many distributed smart grid domain members and their smart devices.

  13. THE APPLICATION OF FORESIGHT PROJECTS IN FORMATION OF TECHNOLOGICAL COMPANIES’ INNOVATION DEVELOPMENT STRATEGY

    Directory of Open Access Journals (Sweden)

    M. E. Zolotareva

    2016-01-01

    Full Text Available In the article is considered the possibility of application of methodology of foresight to the formation of strategy of innovative development of technological companies. The application of existing approaches to defining targets and goals of innovation development does not meet the requirements of the nonlinearity of the modern processes of technological companies’ innovation development.The goals and objectives. The purpose of this article is to study the possibilities of application of methods of foresight in forming of technological companies’ innovation development strategy. To achieve the goal, the author has solved the following problems: considered the interrelationship and interdependence between corporate strategy and technological companies’ innovation development strategy; defined the main problems of formation technological companies’ innovation development strategies; revealed the concept of "foresight" and diff erence in methodology of foresight and traditional forecasting techniques; defined the basic principles of foresight; presents the main stages of the foresight project implementation in technological companies.Research methods. The theoretical basis of the study are the publications of Russian and foreign scientists in the field of formation and development of innovation strategies through the application of foresight methods at the level of national innovation system and at company level. As a methodological basis of the study used methods of analysis, synthesis, induction method, deduction method, the comparison, was applied certain aspects of the synergetic analysis.Summary. The results of Russian and foreign researchers systematized by author confirm the possibility and necessity foresight projects implementation in formation and adjustment of technological companies’ innovation development strategies and in the national innovation system development. The principles of engagement of various social forces

  14. Technology status in support of refined technical baseline for the Spent Nuclear Fuel project. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Puigh, R.J.; Toffer, H.; Heard, F.J.; Irvin, J.J.; Cooper, T.D.

    1995-10-20

    The Spent Nuclear Fuel Project (SNFP) has undertaken technology acquisition activities focused on supporting the technical basis for the removal of the N Reactor fuel from the K Basins to an interim storage facility. The purpose of these technology acquisition activities has been to identify technology issues impacting design or safety approval, to establish the strategy for obtaining the necessary information through either existing project activities, or the assignment of new work. A set of specific path options has been identified for each major action proposed for placing the N Reactor fuel into a ``stabilized`` form for interim storage as part of this refined technical basis. This report summarizes the status of technology information acquisition as it relates to key decisions impacting the selection of specific path options. The following specific categories were chosen to characterize and partition the technology information status: hydride issues and ignition, corrosion, hydrogen generation, drying and conditioning, thermal performance, criticality and materials accountability, canister/fuel particulate behavior, and MCO integrity. This report represents a preliminary assessment of the technology information supporting the SNFP. As our understanding of the N Reactor fuel performance develops the technology information supporting the SNFP will be updated and documented in later revisions to this report. Revision 1 represents the incorporation of peer review comments into the original document. The substantive evolution in our understanding of the technical status for the SNFP (except section 3) since July 1995 have not been incorporated into this revision.

  15. Evaluating the Incorporation of Technology and Application Projects in the Higher Education Mathematics Classroom

    Science.gov (United States)

    Schreyer-Bennethum, Lynn; Albright, Leonard

    2011-01-01

    We report the qualitative and quantitative results of incorporating interdisciplinary application projects and increasing the use of teaching with technology into Calculus I, II and III at the University of Colorado Denver. Minimal changes were made to the curriculum and minimal time was required of instructors to make the changes. Instructors…

  16. Examining the Influence of Technology and Project-Supported Thinking Journey on Achievement

    Science.gov (United States)

    Baran, Medine; Maskan, Abdulkadir

    2013-01-01

    The purpose of this study was to investigate the influence of the technology and project-supported Thinking Journey on 11th grade high school students' achievements in the subject of electricity units. The participants were 68 high school 11th grade students from two different science classes. Control and experimental groups were selected at…

  17. Innovation capabilities in food and beverages and technology-based innovation projects

    NARCIS (Netherlands)

    Tepic, M.; Fortuin, F.T.J.M.; Kemp, R.G.M.; Omta, S.W.F.

    2014-01-01

    Purpose - The aim of this paper is to establish the differences between the food and beverages (F&B) and technology-based industries with regards to the relation between previously identified success factors and innovation project performance. Design/methodology/approach - These differences are

  18. A Costing Model for Project-Based Information and Communication Technology Systems

    Science.gov (United States)

    Stewart, Brian; Hrenewich, Dave

    2009-01-01

    A major difficulty facing IT departments is ensuring that the projects and activities to which information and communications technologies (ICT) resources are committed represent an effective, economic, and efficient use of those resources. This complex problem has no single answer. To determine effective use requires, at the least, a…

  19. OCTAVIUS: a new FP7 project demonstrating CO2 capture technologies

    NARCIS (Netherlands)

    Broutin, P.; Kvamsdal, H.M.; Marca, C. la; Os, P.J. van; Booth, N.

    2013-01-01

    The OCTAVIUS project (Optimisation of CO2 Capture Technology Allowing Verification and Implementation at Utility Scale) has started on March 1st 2012 for a period of 5 years, as part of the 7th Framework Programme of the European Commission. Gathering 15 European and 2 South African partners,

  20. Automatic Speech Recognition and Training for Severely Dysarthric Users of Assistive Technology: The STARDUST Project

    Science.gov (United States)

    Parker, Mark; Cunningham, Stuart; Enderby, Pam; Hawley, Mark; Green, Phil

    2006-01-01

    The STARDUST project developed robust computer speech recognizers for use by eight people with severe dysarthria and concomitant physical disability to access assistive technologies. Independent computer speech recognizers trained with normal speech are of limited functional use by those with severe dysarthria due to limited and inconsistent…

  1. A Costing Model for Project-Based Information and Communication Technology Systems

    Science.gov (United States)

    Stewart, Brian; Hrenewich, Dave

    2009-01-01

    A major difficulty facing IT departments is ensuring that the projects and activities to which information and communications technologies (ICT) resources are committed represent an effective, economic, and efficient use of those resources. This complex problem has no single answer. To determine effective use requires, at the least, a…

  2. Social Informatics: Beyond Technology, A Project in Schools of Social Work in the European Community

    NARCIS (Netherlands)

    Grebel, Harmen; Steyaert, Jan

    1995-01-01

    The authors review the findings of a research project conducted throughout schools of social work in Europe on the level of attention paid to the vocational use of information technology in social work education. Provided is an outline of the research design and an overview of how information techno

  3. Evaluating the Incorporation of Technology and Application Projects in the Higher Education Mathematics Classroom

    Science.gov (United States)

    Schreyer-Bennethum, Lynn; Albright, Leonard

    2011-01-01

    We report the qualitative and quantitative results of incorporating interdisciplinary application projects and increasing the use of teaching with technology into Calculus I, II and III at the University of Colorado Denver. Minimal changes were made to the curriculum and minimal time was required of instructors to make the changes. Instructors…

  4. Using Technology-Enhanced, Cooperative, Group-Project Learning for Student Comprehension and Academic Performance

    Science.gov (United States)

    Tlhoaele, Malefyane; Suhre, Cor; Hofman, Adriaan

    2016-01-01

    Cooperative learning may improve students' motivation, understanding of course concepts, and academic performance. This study therefore enhanced a cooperative, group-project learning technique with technology resources to determine whether doing so improved students' deep learning and performance. A sample of 118 engineering students, randomly…

  5. Innovation capabilities in food and beverages and technology-based innovation projects

    NARCIS (Netherlands)

    Tepic, M.; Fortuin, F.T.J.M.; Kemp, R.G.M.; Omta, S.W.F.

    2014-01-01

    Purpose - The aim of this paper is to establish the differences between the food and beverages (F&B) and technology-based industries with regards to the relation between previously identified success factors and innovation project performance. Design/methodology/approach - These differences are

  6. Vertical and Horizontal Integration of Laboratory Curricula and Course Projects across the Electronic Engineering Technology Program

    Science.gov (United States)

    Zhan, Wei; Goulart, Ana; Morgan, Joseph A.; Porter, Jay R.

    2011-01-01

    This paper discusses the details of the curricular development effort with a focus on the vertical and horizontal integration of laboratory curricula and course projects within the Electronic Engineering Technology (EET) program at Texas A&M University. Both software and hardware aspects are addressed. A common set of software tools are…

  7. OCTAVIUS: a new FP7 project demonstrating CO2 capture technologies

    NARCIS (Netherlands)

    Broutin, P.; Kvamsdal, H.M.; Marca, C. la; Os, P.J. van; Booth, N.

    2013-01-01

    The OCTAVIUS project (Optimisation of CO2 Capture Technology Allowing Verification and Implementation at Utility Scale) has started on March 1st 2012 for a period of 5 years, as part of the 7th Framework Programme of the European Commission. Gathering 15 European and 2 South African partners, OCTAVI

  8. Mission to Mars: A Collaborative Project Infusing Technology and Telecommunications into the Curriculum.

    Science.gov (United States)

    Craig, Dorothy Valcarcel; Stewart, Jaci

    1997-01-01

    Describes a collaborative project involving third and fifth graders that focused on integrating computer technology into the earth science curriculum. Electronic research, telecommunications, science software, and an interdisciplinary approach are discussed; and a list of classroom resources and three worksheets are included. (LRW)

  9. EUROPEAN PROJECTS AS A TOOL FOR IMPROVING FARMERS SKILLS VIA MODERN INFORMATION TECHNOLOGIES

    Directory of Open Access Journals (Sweden)

    Zuzana PALKOVA

    2013-01-01

    Full Text Available This article presents European projects with the main focus on the improving the skills and competitiveness of farmers by modern information and communication technologies and e-learning methods. Two projects – AVARES - Enhance attractiveness of renewable energy training by virtual reality and NewCAP - New European Standards in the Context of Reformed EU Common Agricultural Policy are projects under the Leonardo da Vinci Transfer ofInnovation grant scheme. They try to present new way of vocational education and training in the agrosector. The main aim of the AVARES project is to develop the multimedia learning materials for vocational education and training in the field of agricultural and rural development and application of modern information and communication technologies into vocational education and training. The emphasis is put on the application of modern ICT equipment and technologies, with the main focus on the Virtual reality, 3D visual display and e - learning 2.0 methods. New programming period 2014 – 2020 will bring significant changes within the Common Agricultural Policy (CAP which will have a serious impact on economy especially of larger beneficiaries. The „NewCAP“ project aiming at preparation of actors in rural areas to take the proposed changes in the policy through interactive educational programme.

  10. Evaluating the incorporation of technology and application projects in the higher education mathematics classroom

    Science.gov (United States)

    Schreyer-Bennethum, Lynn; Albright, Leonard

    2011-01-01

    We report the qualitative and quantitative results of incorporating interdisciplinary application projects and increasing the use of teaching with technology into Calculus I, II and III at the University of Colorado Denver. Minimal changes were made to the curriculum and minimal time was required of instructors to make the changes. Instructors were given one 3-hour introduction to teaching with technology, a 3-hour introduction to one or two interdisciplinary problems to be used in the class, and course instructors met with each other no more than 1 hour per week. To evaluate the effectiveness of these modifications, 24 students were interviewed four times during a 2 year time span, student comments from student evaluations regarding the application projects were recorded, and the grade-point averages (GPAs) of four groups of 40 students for the year following their completion of Calculus III were analysed. The results show that students' enthusiasm and interest in interdisciplinary application projects were greater when the projects were enthusiastically endorsed by the instructor, but even with mixed instructor enthusiasm, incorporating application projects and increasing the use of technology in the classroom increase the well-roundedness of students' education and increase their performance in more advanced courses as measured by their overall GPA for the year following their Calculus III math class.

  11. An Arabidopsis ctpA homologue is involved in the repair of photosystem Ⅱ under high light

    Institute of Scientific and Technical Information of China (English)

    YIN ShuMing; SUN XuWu; ZHANG LiXin

    2008-01-01

    A T-DNA insertion mutant AtctpA 1 was identified to study the physiological roles of a carboxyl-terminal processing protease (CtpA) homologue in Arabidopsis. Under normal growth conditions, disruption of AtctpA1 did not result in any apparent alterations in growth rate and thylakoid membrane protein components. However the mutant plants exhibited increased sensitivity to high irradiance. Degradation of PSII reaction center protein D1 was accelerated in the mutant during photoinhibition. These results demostrated that AtctpA1 was required for efficient repair of PSII in Arabidopsis under high irradiance.

  12. Fighting Testing ACAT/FRRP: Automatic Collision Avoidance Technology/Fighter Risk Reduction Project

    Science.gov (United States)

    Skoog, Mark A.

    2009-01-01

    This slide presentation reviews the work of the Flight testing Automatic Collision Avoidance Technology/Fighter Risk Reduction Project (ACAT/FRRP). The goal of this project is to develop common modular architecture for all aircraft, and to enable the transition of technology from research to production as soon as possible to begin to reduce the rate of mishaps. The automated Ground Collision Avoidance System (GCAS) system is designed to prevent collision with the ground, by avionics that project the future trajectory over digital terrain, and request an evasion maneuver at the last instance. The flight controls are capable of automatically performing a recovery. The collision avoidance is described in the presentation. Also included in the presentation is a description of the flight test.

  13. Assessing the maturity and re-usability of NASA's Advanced Information System Technology (AIST) Projects

    Science.gov (United States)

    Little, M. M.; Hines, K.

    2016-12-01

    Considerable funding has been invested in Earth science information technology (IT) projects by NASA over the past 15 years. While many of these projects succeeded at completing their objectives, rapid improvements in technology and growth in available data could further enhance the capabilities available to the Earth science community. Independent evaluation of these projects has become more and more important. Not only do they qualify the maturity of the work, but they give potential adopters the chance to kick the tires. One approach that has been used is to task Federally Funded Research and Development Corporations (FFRDC) with reviews and paper studies. Another approach involves field testing by third parties. Over the past three years, the AIST Program has tried both. This paper will describe both approaches and lessons learned from the experiences. The audience will be asked for their suggestions as to how to qualify and value these results.

  14. Structures and Design Phase I Summary for the NASA Composite Cryotank Technology Demonstration Project

    Science.gov (United States)

    Johnson, Ted; Sleight, David W.; Martin, Robert A.

    2013-01-01

    A description of the Phase I structures and design work of the Composite Cryotank Technology Demonstration (CCTD) Project is in this paper. The goal of the CCTD Project in the Game Changing Development (GCD) Program is to design and build a composite liquid-hydrogen cryogenic tank that can save 30% in weight and 25% in cost compared to state-of-the-art aluminum metallic cryogenic tank technology when the wetted composite skin wall is at an allowable strain of 5000 in/in. Three Industry teams developed composite cryogenic tank concepts that are compared for weight to an aluminum-lithium (Al-Li) cryogenic tank designed by NASA in Phase I of the CCTD Project. The requirements used to design all of the cryogenic tanks in Phase I will be discussed and the resulting designs, analyses, and weight of the concepts developed by NASA and Industry will be reviewed and compared.

  15. Fostering renewable energy in small developing island states through knowledge and technology transfer: the - DIREKT Project

    Energy Technology Data Exchange (ETDEWEB)

    Leal, Walter; Schulte, Veronika; Gottwald, Julia

    2010-07-01

    Full text: It is widely acknowledged that the use of renewable energy may assist developing countries as a whole and Small Island States in particular, in addressing their energy needs and at the same time reducing their dependence on fossil fuels. In order to support these efforts, the project Small Developing Island Renewable Energy Knowledge and Technology Transfer Network (DIREKT) is being undertaken. DIREKT is a cooperation scheme involving universities from Germany, Fiji, Mauritius and Trinidad et Tobago with the aim of strengthening their science and technology capacity in the field of renewable energy, by means of technology transfer, information exchange and networking. Developing countries are especially vulnerable to problems associated with climate change and much can be gained by raising their capacity in the field of renewable energy, which is a key area. This paper introduces the project DIREKT, its aims and the partnership. It will also show how sustainable cooperation between the science and technology communities of ACP and EU institutions in the key area of Renewable Energy may be achieved, which is of great relevance for the socio-economic development of small island developing states. One of features of the project, namely the establishment of Research and Technology Transfer Centres within each of the partner countries, will be presented. (Author)

  16. Infliximab biosimilar CT-P13 therapy is effective and safe in maintaining remission in Crohn's disease and ulcerative colitis - experiences from a single center.

    Science.gov (United States)

    Farkas, Klaudia; Rutka, Mariann; Ferenci, Tamás; Nagy, Ferenc; Bálint, Anita; Bor, Renáta; Milassin, Ágnes; Fábián, Anna; Szántó, Kata; Végh, Zsuzsanna; Kürti, Zsuzsanna; Lakatos, Péter L; Szepes, Zoltán; Molnár, Tamás

    2017-08-18

    CT-P13, the first biosimilar monoclonal antibody to infliximab (IFX), has been confirmed to be efficacious in inducing remission in inflammatory bowel diseases (IBD). The aim of this study was to evaluate the long-term efficacy and safety of CT-P13 therapy in Crohn's disease (CD) and ulcerative colitis (UC), and to identify predictors of sustained clinical response during a 54-week CT-P13 treatment period. Patients with CD and UC, who were administered CT-P13, were prospectively enrolled. Clinical response was assessed at week 14 and week 54. Predictive factors for disease outcome at week 54 were evaluated. 57 CD and 57 UC patients were included; 55 CD and 49 UC patients completed the induction therapy and 50 CD and 46 UC patients completed the 54-week treatment period. Clinical remission was achieved in 65.5% of CD and 75.5% of UC patients at week 14. Rate of continuous clinical response was 51% in both CD and UC at week 54. None of the examined parameters were predictive to the clinical outcome neither in CD, nor in UC. This study confirmed the long-term efficacy and safety of CT-P13 therapy in IBD. Response rates at week 54 were similar in CD and UC.

  17. Reducing Plug Loads in Office Spaces: Hawaii and Guam Energy Improvement Technology Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Sheppy, M.; Metzger, I.; Cutler, D.; Holland, G.; Hanada, A.

    2014-01-01

    As part of its overall strategy to meet its energy goals, the Naval Facilities Engineering Command (NAVFAC) partnered with the Department of Energy's National Renewable Energy Laboratory (NREL) to rapidly demonstrate and deploy cost-effective renewable energy and energy efficiency technologies. This project was one of several demonstrations of new or underutilized commercial energy technologies. The common goal was to demonstrate and measure the performance and economic benefit of the system while monitoring any ancillary impacts to related standards of service and operation and maintenance (O&M) practices. In short, demonstrations at naval facilities simultaneously evaluate the benefits and compatibility of the technology with the U.S. Department of Defense (DOD) mission, and with NAVFAC's design, construction, operations, and maintenance practices, in particular. This project demonstrated the performance of commercially available advanced power strips (APSs) for plug load energy reductions in building A4 at Joint Base Pearl Harbor-Hickam (JBPHH), Hawaii.

  18. Public demonstration projects and field trials: Accelerating commercialisation of sustainable technology in solar photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Brown, James [Cass Business School, City University, 106 Bunhill Row, London EC1Y 8TZ (United Kingdom)], E-mail: j.e.brown@city.ac.uk; Hendry, Chris [Cass Business School, City University, 106 Bunhill Row, London EC1Y 8TZ (United Kingdom)], E-mail: c.n.hendry@city.ac.uk

    2009-07-15

    The paper considers the role of government funded demonstration projects and field trials (DTs) in accelerating the commercialisation of new energy technologies that meet a public good but do not have immediate market appeal [Sagar, A.D., van der Zwaan, B., 2006. Technological innovation in the energy sector: R and D, deployment, and learning-by-doing. Energy Policy 34, 2601-2608]. Drawing on an original database of DTs in the EU, Japan and USA from 1973 to 2004, we review the history of DTs in photovoltaic technology for electricity generation, and its subsequent take up as a commercial energy source. We find that DTs that are aimed purely at discovering suitable market opportunities are less successful in achieving diffusion than projects that target a particular application and concentrate resources on it. The former nevertheless have a vital role to play in the learning process, while a targeted focus is often dependent on national industrial and institutional factors.

  19. Public demonstration projects and field trials. Accelerating commercialisation of sustainable technology in solar photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Brown, James; Hendry, Chris [Cass Business School, City University, 106 Bunhill Row, London EC1Y 8TZ (United Kingdom)

    2009-07-15

    The paper considers the role of government funded demonstration projects and field trials (DTs) in accelerating the commercialisation of new energy technologies that meet a public good but do not have immediate market appeal [Sagar, A.D., van der Zwaan, B., 2006. Technological innovation in the energy sector: R and D, deployment, and learning-by-doing. Energy Policy 34, 2601-2608]. Drawing on an original database of DTs in the EU, Japan and USA from 1973 to 2004, we review the history of DTs in photovoltaic technology for electricity generation, and its subsequent take up as a commercial energy source. We find that DTs that are aimed purely at discovering suitable market opportunities are less successful in achieving diffusion than projects that target a particular application and concentrate resources on it. The former nevertheless have a vital role to play in the learning process, while a targeted focus is often dependent on national industrial and institutional factors. (author)

  20. Performance Evaluation Management and Meta-norm Execution Cost of Major Science and Technology Project

    Institute of Scientific and Technical Information of China (English)

    Jianghua; HU

    2013-01-01

    Major science and technology project generally got high social expectations as a result of harge investment.To ensure that the science and technology teams follow the norms of S&T research and make full use of the investment,the effective norms maintenance mechanism must be established which includes punishment for violators and burnout of teams of supervisors,namely setting up the meta-norm execution mechanism.It is very important to establish the effective major science and technology project evaluation system to reduce the norm and metanorm execution cost.In this paper,the principles,methods and implementation system guarantee of evaluation system building are studied as well.

  1. The Development of Future Technology Teachers’ Artistic-Projective Abilities: Foreign Experience

    Directory of Open Access Journals (Sweden)

    Kurach Mykola

    2016-03-01

    Full Text Available The necessity to form and develop future technology teachers’ creative abilities has been stressed in the article. The psychologic-pedagogical researches of the leading specialists from Europe, the USA and Japan in the field of creative work and creativity have been analyzed. The main problems of the creative artistic-projective abilities development have been determined based on the analysis and synthesis of foreign and native philosophic, pedagogical and psychological literature dedicated to characteristics of such notions as “creative work” and “creativity”. Approaches and conceptions providing students – future technology teachers – with creative activities have been singled out. The gist of psychological mechanism for forming teachers’ creative personality has been established and its basic features have been determined as a result of the world experience of the theory and methods of creative abilities development generalization. The main features are as follows: an independence and an inclination towards divergent behavior; flexibility of thinking and readiness for everything new; motivation for self-actualization; striving for self-expressing and ability to creative work; ability to find out how to set and solve the problems. It has been mentioned that the technology teachers’ artistic-projective activity requires their creative abilities development, which, in their turn, are formed on the ground of well-developed general and special (art, projective, technological, pedagogical potencies. Therefore, the effectiveness of the students’ art-projective knowledge and skills forming depends upon the extent their general, special and creative abilities have been developed. That is why skillful and pedagogically correct organization of future technology teachers’ artistic-projective activities will inevitably provide the higher qualitatively new level of their creative abilities and creativity.

  2. Final Report: Fire Prevention, Detection, and Suppression Project, Exploration Technology Development Program

    Science.gov (United States)

    Ruff, Gary A.

    2011-01-01

    The Fire Prevention, Detection, and Suppression (FPDS) project is a technology development effort within the Exploration Technology Development Program of the Exploration System Missions Directorate (ESMD) that addresses all aspects of fire safety aboard manned exploration systems. The overarching goal for work in the FPDS area is to develop technologies that will ensure crew health and safety on exploration missions by reducing the likelihood of a fire, or, if one does occur, minimizing the risk to the crew, mission, or system. This is accomplished by addressing the areas of (1) fire prevention and material flammability, (2) fire signatures and detection, and (3) fire suppression and response. This report describes the outcomes of this project from the formation of the Exploration Technology Development Program (ETDP) in October 2005 to September 31, 2010 when the Exploration Technology Development Program was replaced by the Enabling Technology Development and Demonstration Program. NASA s fire safety work will continue under this new program and will build upon the accomplishments described herein.

  3. E-Learning and the Use of New Technologies in the "Kolumbus-Kids" Project in Germany

    Science.gov (United States)

    Wegner, Claas; Homann, Wiebke; Strehlke, Friederike; Borgmann, Annika

    2014-01-01

    This article presents the science project "Kolumbus-Kids" as an example of the innovative use of "E-Learning" and other "new technologies" to advance student learning and new-media education. The project benefits from various technology-based education strategies and E-Learning scenarios which are employed during the…

  4. E-Learning and the Use of New Technologies in the "Kolumbus-Kids" Project in Germany

    Science.gov (United States)

    Wegner, Claas; Homann, Wiebke; Strehlke, Friederike; Borgmann, Annika

    2014-01-01

    This article presents the science project "Kolumbus-Kids" as an example of the innovative use of "E-Learning" and other "new technologies" to advance student learning and new-media education. The project benefits from various technology-based education strategies and E-Learning scenarios which are employed during the…

  5. Xinjiang Xinxin Mining Starts to Work on a 10,O00-ton Nickel-smelting Technological Upgrading Project

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>In October,Xinjiang Xinxin Mining Industry Co.,Ltd.started to work on a 10,000-ton nickel-smelting technological upgrading project at the Kalatongke copper nickel ore in Fuyun County.The technological upgrading project for 10,000-ton nickel-smelting operations that

  6. Progress of the Photovoltaic Technology Incubator Project Towards an Enhanced U.S. Manufacturing Base: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Ullal, H.; Mitchell, R.; Keyes, B.; VanSant, K.; von Roedern, B.; Symko-Davies, M.; Kane, V.

    2011-07-01

    In this paper, we report on the major accomplishments of the U.S. Department of Energy's (DOE) Solar Energy Technologies Program (SETP) Photovoltaic (PV) Technology Incubator project. The Incubator project facilitates a company's transition from developing a solar cell or PV module prototype to pilot- and large-scale U.S. manufacturing. The project targets small businesses that have demonstrated proof-of-concept devices or processes in the laboratory. Their success supports U.S. Secretary of Energy Steven Chu's SunShot Initiative, which seeks to achieve PV technologies that are cost-competitive without subsidies at large scale with fossil-based energy sources by the end of this decade. The Incubator Project has enhanced U.S. PV manufacturing capacity and created more than 1200 clean energy jobs, resulting in an increase in American economic competitiveness. The investment raised to date by these PV Incubator companies as a result of DOE's $ 59 million investment totals nearly $ 1.3 billion.

  7. The Dust Management Project: Characterizing Lunar Environments and Dust, Developing Regolith Mitigation Technology and Simulants

    Science.gov (United States)

    Hyatt, Mark J.; Straka, Sharon A.

    2010-01-01

    A return to the Moon to extend human presence, pursue scientific activities, use the Moon to prepare for future human missions to Mars, and expand Earth?s economic sphere, will require investment in developing new technologies and capabilities to achieve affordable and sustainable human exploration. From the operational experience gained and lessons learned during the Apollo missions, conducting long-term operations in the lunar environment will be a particular challenge, given the difficulties presented by the unique physical properties and other characteristics of lunar regolith, including dust. The Apollo missions and other lunar explorations have identified significant lunar dust-related problems that will challenge future mission success. Comprised of regolith particles ranging in size from tens of nanometers to microns, lunar dust is a manifestation of the complex interaction of the lunar soil with multiple mechanical, electrical, and gravitational effects. The environmental and anthropogenic factors effecting the perturbation, transport, and deposition of lunar dust must be studied in order to mitigate it?s potentially harmful effects on exploration systems and human explorers. The Dust Management Project (DMP) is tasked with the evaluation of lunar dust effects, assessment of the resulting risks, and development of mitigation and management strategies and technologies related to Exploration Systems architectures. To this end, the DMP supports the overall goal of the Exploration Technology Development Program (ETDP) of addressing the relevant high priority technology needs of multiple elements within the Constellation Program (CxP) and sister ETDP projects. Project scope, plans, and accomplishments will be presented.

  8. An integrated ball projection technology for the study of dynamic interceptive actions.

    Science.gov (United States)

    Stone, J A; Panchuk, D; Davids, K; North, J S; Fairweather, I; Maynard, I W

    2014-12-01

    Dynamic interceptive actions, such as catching or hitting a ball, are important task vehicles for investigating the complex relationship between cognition, perception, and action in performance environments. Representative experimental designs have become more important recently, highlighting the need for research methods to ensure that the coupling of information and movement is faithfully maintained. However, retaining representative design while ensuring systematic control of experimental variables is challenging, due to the traditional tendency to employ methods that typically involve use of reductionist motor responses such as buttonpressing or micromovements. Here, we outline the methodology behind a custom-built, integrated ball projection technology that allows images of advanced visual information to be synchronized with ball projection. This integrated technology supports the controlled presentation of visual information to participants while they perform dynamic interceptive actions. We discuss theoretical ideas behind the integration of hardware and software, along with practical issues resolved in technological design, and emphasize how the system can be integrated with emerging developments such as mixed reality environments. We conclude by considering future developments and applications of the integrated projection technology for research in human movement behaviors.

  9. Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product*

    Science.gov (United States)

    Dunne, Matthew; Leicht, Stefan; Krichel, Boris; Thompson, Andrew; Gómez-Torres, Natalia; Garde, Sonia; Narbad, Arjan; Mayer, Melinda J.

    2016-01-01

    Bacteriophages produce endolysins, which lyse the bacterial host cell to release newly produced virions. The timing of lysis is regulated and is thought to involve the activation of a molecular switch. We present a crystal structure of the activated endolysin CTP1L that targets Clostridium tyrobutyricum, consisting of a complex between the full-length protein and an N-terminally truncated C-terminal cell wall binding domain (CBD). The truncated CBD is produced through an internal translation start site within the endolysin gene. Mutants affecting the internal translation site change the oligomeric state of the endolysin and reduce lytic activity. The activity can be modulated by reconstitution of the full-length endolysin-CBD complex with free CBD. The same oligomerization mechanism applies to the CD27L endolysin that targets Clostridium difficile and the CS74L endolysin that targets Clostridium sporogenes. When the CTP1L endolysin gene is introduced into the commensal bacterium Lactococcus lactis, the truncated CBD is also produced, showing that the alternative start codon can be used in other bacterial species. The identification of a translational switch affecting oligomerization presented here has implications for the design of effective endolysins for the treatment of bacterial infections. PMID:26683375

  10. Overview of the NASA Environmentally Responsible Aviation Project's Propulsion Technology Portfolio

    Science.gov (United States)

    Suder, Kenneth L.

    2012-01-01

    The NASA Environmentally Responsible Aviation (ERA) Project is focused on developing and demonstrating integrated systems technologies to TRL 4-6 by 2020 that enable reduced fuel burn, emissions, and noise for futuristic air vehicles. The specific goals aim to simultaneously reduce fuel burn by 50%, reduce Landing and Take-off Nitrous Oxides emissions by 75% relative to the CAEP 6 guidelines, and reduce cumulative noise by 42 Decibels relative to the Stage 4 guidelines. These goals apply to the integrated vehicle and propulsion system and are based on a reference mission of 3000nm flight of a Boeing 777-200 with GE90 engines. This paper will focus primarily on the ERA propulsion technology portfolio, which consists of advanced combustion, propulsor, and core technologies to enable these integrated air vehicle systems goals. An overview of the ERA propulsion technologies will be described and the status and results to date will be presented.

  11. Variable conductance heat pipe technology. [research project resulting in heat pipe experiment on OAO-3 satellite

    Science.gov (United States)

    Anderson, W. T.; Edwards, D. K.; Eninger, J. E.; Marcus, B. D.

    1974-01-01

    A research and development program in variable conductance heat pipe technology is reported. The project involved: (1) theoretical and/or experimental studies in hydrostatics, (2) hydrodynamics, (3) heat transfer into and out of the pipe, (4) fluid selection, and (5) materials compatibility. The development, fabrication, and test of the space hardware resulted in a successful flight of the heat pipe experiment on the OAO-3 satellite. A summary of the program is provided and a guide to the location of publications on the project is included.

  12. Funding and Strategic Alignment Guidance for Infusing Small Business Innovation Research Technology into Aeronautics Research Mission Directorate Projects for 2016

    Science.gov (United States)

    Nguyen, Hung D.; Steele, Gynelle C.

    2017-01-01

    This report is intended to help NASA program and project managers incorporate Small Business Innovation Research (SBIR) technologies into NASA Aeronautics Research Mission Directorate (ARMD) projects. Other Government and commercial project managers interested in ARMD funding opportunities through NASA's SBIR program will find this report useful as well.

  13. Evaluation of Project Based Learning in the Area of Manufacturing and Statistics in the Degree of Industrial Technology

    Science.gov (United States)

    Buj-Corral, Irene; Marco-Almagro, Lluís; Riba, Alex; Vivancos-Calvet, Joan; Tort-Martorell, Xavier

    2015-01-01

    In the subject Project I in the second year of the Degree in Industrial Technology Engineering taught at the School of Industrial Engineering of Barcelona (ETSEIB), subgroups of 3-4 students within groups of 20 students develop a project along a semester. Results of 2 projects are presented related to manufacturing, measurement of parts and the…

  14. The Impact of Project Role on Perceptions of Risk and Performance in Information Technology Software Development: A Comparative Analysis

    Science.gov (United States)

    Okongo, James

    2014-01-01

    The failure rate of information technology (IT) development projects is a significant concern for today's organizations. Perceptions of IT project risk and project performance have been identified as important factors by scholars studying the topic, and Wallace, Keil, and Rai (2004a) developed a survey instrument to measure how dimensions of…

  15. The Impact of Project Role on Perceptions of Risk and Performance in Information Technology Software Development: A Comparative Analysis

    Science.gov (United States)

    Okongo, James

    2014-01-01

    The failure rate of information technology (IT) development projects is a significant concern for today's organizations. Perceptions of IT project risk and project performance have been identified as important factors by scholars studying the topic, and Wallace, Keil, and Rai (2004a) developed a survey instrument to measure how dimensions of…

  16. Using the regularities of high and critical technologies developing in innovative project management

    Directory of Open Access Journals (Sweden)

    S. G. Selivanov

    2014-01-01

    Full Text Available Problem-orientated to the innovative activity, computer-aided systems of production engineering (CASPE integrates design, manufacture, and organization activities using the interrelated innovation principles thus leaning the innovative activity towards the creation of innovative products and technological innovations of high science and technology level and efficiency. In this situation the innovative activity uses in practice not only the newest experience, but also the science laws and consequences, that is, in particular, “Science of Innovations”. The mentioned science laws explain wave dynamics of technical (technological systems development. In the course of innovation activities and/or innovation designing a modification of continuously acting technological system, usually, causes its developing and growing upwards by Sshaped curve. Changing a principle of action changes S-shaped curve development (Fig. 1. If such changes are within the certain “trace tube” we are entitled to state the steady system development.Analysis of changing target function of technological system within the “trace tube” of its steady development characterizes its growing wave dynamics (Fig. 1 using the S-shaped curves (sigmoid type relations. S-shaped innovative development relations of technological systems are, usually, explained by different mathematical models, each being in compliance with the certain process of science and technology. Singular innovative project management using the S-shaped curves can be explained by the following example (Fig.2.To use such management technique it is very important to know the mathematical models of S-curves for different types of innovation projects. That is why we consider given S-shaped relations in-detail for:- developing the high and critical technologies during R&D implementation using the cutting-edge CASSR (computer-aided systems of scientific research of high and critical technologies in innovation

  17. A Human Resource Development Program for Information Technology Engineers using Project-Based Learning

    Directory of Open Access Journals (Sweden)

    Minoru Nakayama

    2012-11-01

    Full Text Available This paper reports the case of an educational practice and evaluation of team learning using project-based learning to develop Information Technology engineers. This program aims to develop the competencies of engineers, such as their communication skills, problem solving within teams, and other abilities. Its subject is the “Upper Process” of Information Technology systems development. To determine the feasibility of the course, it was conducted at a computer college. The team’s products and team learning activities were evaluated using rubrics and self evaluation inventories, and learning performance was discussed. Also, the evaluation of the learning management system affected the learning activity.

  18. Optics Design for the U.S. SKA Technology Development Project Design Verification Antenna

    Science.gov (United States)

    Imbriale, W. A.; Baker, L.; Cortes-Medellin, G.

    2012-01-01

    The U.S. design concept for the Square Kilometer Array (SKA) program is based on utilizing a large number of 15 meter dish antennas. The Technology Development Project (TDP) is planning to design and build the first of these antennas to provide a demonstration of the technology and a solid base on which to estimate costs. This paper describes the performance of the selected optics design. It is a dual-shaped offset Gregorian design with a feed indexer that can accommodate corrugated horns, wide band single pixel feeds or phased array feeds.

  19. Optics Design for the U.S. SKA Technology Development Project Design Verification Antenna

    Science.gov (United States)

    Imbriale, W. A.; Baker, L.; Cortes-Medellin, G.

    2012-01-01

    The U.S. design concept for the Square Kilometer Array (SKA) program is based on utilizing a large number of 15 meter dish antennas. The Technology Development Project (TDP) is planning to design and build the first of these antennas to provide a demonstration of the technology and a solid base on which to estimate costs. This paper describes the performance of the selected optics design. It is a dual-shaped offset Gregorian design with a feed indexer that can accommodate corrugated horns, wide band single pixel feeds or phased array feeds.

  20. Fire protection research for energy technology projects; FY 79 year-end report

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, H.K.; Alvares, N.J.; Lipska, A.E.; Ford, H.; Beason, D.G.

    1981-01-01

    This report describes work performed in fiscal year 1979, on a DOE funded study entitled Fire Protection Research for Energy Technology Projects. The primary goal of this program is to ensure that fire protection measures for Fusion Energy Experiments (FEE) evolve concurrently with the complexity of FEE. Ultimately, it is planned that the detailed study of fusion experiments will provide an analytical methodology which can be applied to the full range of energy technology projects. We attempt to achieve this objective by coordinately advancing 3 (three) major task areas; (a) determine the fire hazards of current FEE facilities (b) assess the ability of accepted fire management strategies to meet and negate the hazard, (c) perform unique research into problem areas we have identified to provide input into analytical fire growth and damage assessment models.

  1. Enabling technologies for space exploration systems: The STEPS project results and perspectives

    Science.gov (United States)

    Messidoro, Piero; Perino, Maria Antonietta; Boggiatto, Dario

    2013-05-01

    The project STEPS (Sistemi e Tecnologie per l'EsPlorazione Spaziale) is a joint development of technologies and systems for Space Exploration supported by Regione Piemonte, the European Regional Development Fund (E.R.D.F.) 2007-2013, Thales Alenia Space Italia (TAS-I), SMEs, Universities and public Research Centres belonging to the network "Comitato Distretto Aerospaziale del Piemonte" the Piedmont Aerospace District (PAD) in Italy. The project first part terminated in May 2012 with a final demonstration event that summarizes the technological results of research activities carried-out during a period the three years and half. The project developed virtual and hardware demonstrators for a range of technologies for the descent, soft landing and surface mobility of robotic and manned equipment for Moon and Mars exploration. The two key hardware demonstrators—a Mars Lander and a Lunar Rover—fit in a context of international cooperation for the exploration of Moon and Mars, as envisaged by Space Agencies worldwide. The STEPS project included also the development and utilization of a system of laboratories equipped for technology validation, teleoperations, concurrent design environments, and virtual reality simulation of the Exploration Systems in typical Moon and Mars environments. This paper presents the reached results in several technology domains like: vision-based GNC for the last portion of Mars Entry, Descent and Landing sequence, Hazard avoidance and complete spacecraft autonomy; Autonomous Rover Navigation, based on the determination of the terrain morphology by a stereo camera; Mobility and Mechanisms providing an Integrated Ground Mobility System, Rendezvous and Docking equipment, and protection from Environment effects; innovative Structures such as Inflatable, Smart and Multifunction Structures, an Active Shock Absorber for safe landing, balance restoring and walking; Composite materials Modelling and Monitoring; Human-machine interface features of a

  2. Next Generation Life Support Project: Development of Advanced Technologies for Human Exploration Missions

    Science.gov (United States)

    Barta, Daniel J.

    2012-01-01

    Next Generation Life Support (NGLS) is one of several technology development projects sponsored by the National Aeronautics and Space Administration s Game Changing Development Program. NGLS is developing life support technologies (including water recovery, and space suit life support technologies) needed for humans to live and work productively in space. NGLS has three project tasks: Variable Oxygen Regulator (VOR), Rapid Cycle Amine (RCA) swing bed, and Alternative Water Processing. The selected technologies within each of these areas are focused on increasing affordability, reliability, and vehicle self sufficiency while decreasing mass and enabling long duration exploration. The RCA and VOR tasks are directed at key technology needs for the Portable Life Support System (PLSS) for an Exploration Extravehicular Mobility Unit (EMU), with focus on prototyping and integrated testing. The focus of the Rapid Cycle Amine (RCA) swing-bed ventilation task is to provide integrated carbon dioxide removal and humidity control that can be regenerated in real time during an EVA. The Variable Oxygen Regulator technology will significantly increase the number of pressure settings available to the space suit. Current spacesuit pressure regulators are limited to only two settings while the adjustability of the advanced regulator will be nearly continuous. The Alternative Water Processor efforts will result in the development of a system capable of recycling wastewater from sources expected in future exploration missions, including hygiene and laundry water, based on natural biological processes and membrane-based post treatment. The technologies will support a capability-driven architecture for extending human presence beyond low Earth orbit to potential destinations such as the Moon, near Earth asteroids and Mars.

  3. Technology Outlook for STEM+ Education 2013-2018: An NMC Horizon Project Sector Analysis

    Science.gov (United States)

    Johnson, L.; Adams Becker, S.; Estrada, V.; Martín, S.

    2013-01-01

    The "Technology Outlook for STEM+ Education 2013-2018: An NMC Horizon Project Sector Analysis" reflects a collaborative research effort between the New Media Consortium (NMC), the Centro Superior para la Enseñanza Virtual (CSEV), the Departamento de Ingeniería Eléctrica, Electrónica y de Control at the Universidad Nacional de Educación a…

  4. Nuclear propulsion technology development - A joint NASA/Department of Energy project

    Science.gov (United States)

    Clark, John S.

    1992-01-01

    NASA-Lewis has undertaken the conceptual development of spacecraft nuclear propulsion systems with DOE support, in order to establish the bases for Space Exploration Initiative lunar and Mars missions. This conceptual evolution project encompasses nuclear thermal propulsion (NTP) and nuclear electric propulsion (NEP) systems. A technology base exists for NTP in the NERVA program files; more fundamental development efforts are entailed in the case of NEP, but this option is noted to offer greater advantages in the long term.

  5. Application of New Techniques, Materials and Technologies in West-East Gas Transportation Pipeline Project

    Institute of Scientific and Technical Information of China (English)

    DongXu

    2004-01-01

    With the application of new techniques, materials and technologies in West-East Gas Transportation Pipeline (WEGTP) project, the design concept of domestic pipeline industrial construction has been updated, speeding up the development and improvement of the strength as a whole in aspects of smelting industry, pipe fabrication, pipeline construction and equipment manufacture, making China's pipeline industry catch up with the trend of development of the world advanced level.

  6. Nuclear propulsion technology development - A joint NASA/Department of Energy project

    Science.gov (United States)

    Clark, John S.

    1992-01-01

    NASA-Lewis has undertaken the conceptual development of spacecraft nuclear propulsion systems with DOE support, in order to establish the bases for Space Exploration Initiative lunar and Mars missions. This conceptual evolution project encompasses nuclear thermal propulsion (NTP) and nuclear electric propulsion (NEP) systems. A technology base exists for NTP in the NERVA program files; more fundamental development efforts are entailed in the case of NEP, but this option is noted to offer greater advantages in the long term.

  7. FEATURES OF THE PROJECT-ORIENTED MANAGEMENT OF HIGH-TECHNOLOGY ENTERPRISES

    Directory of Open Access Journals (Sweden)

    E. D. Dobrova

    2016-01-01

    Full Text Available This article is explored the concept of "project portfolio", defined the role and place of project portfolio management in the overall enterprise management structure, the formation of the project portfolio and its limitations. The aim of the article is to study the role and place of project management in the overall enterprise management system, and the relationship of the management processes at diff erent organizational levels.The formation of the strategic projects portfolio of the company – it is an urgent task which is associated with the strengthening of innovation and investment activity of the operating in Russia enterprises. Nowadays, transfer of enterprises activities to an innovative way of development is going on in the face of the deteriorating international situation, Russia's isolation from European countries and the United States, and the implementation of the sanctions policy, changes in the domestic economic and political course. These circumstances, of course, could not aff ect the adjustment of activities and strategic goals of the development of enterprises, at the level of their financial and economic stability. At the same time, the growth of innovation activity in a number of sectors, particularly in high-technology industries, it creates the need for the formation of the project portfolio, which allows to achieve the strategic objectives of enterprises and enhance their competitiveness.During the preparation of the article there were identified a core set of problems faced by the enterprises during the transition to a model of the project management, which is due, primarily, poor project management technologies in Russia, and it is complicated by the lack of a clear definition of objectives and vision benefits for enterprises. In addition, the reasons for the backlog are caused by the low level of project management maturity of the enterprise, which is caused by a lack of personnel with expertise in this field of

  8. Milliken Clean Coal Technology Demonstration Project. Environmental monitoring report, July--September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    New York State Electric and Gas Corporation (NYSEG) has installed and is presently operating a high-efficiency flue gas desulfurization (FGD) system to demonstrate innovative emissions control technology and comply with the Clean Air Act Amendments of 1990. The host facility for this demonstration project is NYSEG`s Milliken Station, in the Town of Lansing, New York. The primary objective of this project is to demonstrate a retrofit of energy-efficient SO{sub 2} and NO{sub x} control systems with minimal impact on overall plant efficiency. The demonstration project has added a forced oxidation, formic acid-enhanced wet limestone FGD system, which is expected to reduce SO{sub 2} emissions by at least 90 percent. NYSEG also made combustion modifications to each boiler and plans to demonstrate selective non-catalytic reduction (SNCR) technology on unit 1, which will reduce NO{sub x} emissions. Goals of the proposed demonstration include up to 98 percent SO{sub 2} removal efficiency while burning high-sulfur coal, 30 percent NO{sub x} reductions through combustion modifications, additional NO{sub x} reductions using SNCR technology, production of marketable commercial-grade gypsum and calcium chloride by-products to minimize solid waste disposal, and zero wastewater discharge.

  9. Milliken Clean Coal Technology Demonstration Project. Environmental monitoring report, July--September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    New York State Electric and Gas Corporation (NYSEG) has installed and is presently operating a high-efficiency flue gas desulfurization (FGD) system to demonstrate innovative emissions control technology and comply with the Clean Air Act Amendments of 1990. The host facility for this demonstration project is NYSEG`s Milliken Station, in the Town of Lansing, New York. The primary objective of this project is to demonstrate a retrofit of energy-efficient SO{sub 2} and NO{sub x} control systems with minimal impact on overall plant efficiency. The demonstration project has added a forced oxidation, formic acid-enhanced wet limestone FGD system, which is expected to reduce SO{sub 2} emissions by at least 90 percent. NYSEG also made combustion modifications to each boiler and plans to demonstrate selective non-catalytic reduction (SNCR) technology on unit 1, which will reduce NO{sub x} emissions. Goals of the proposed demonstration include up to 98 percent SO{sub 2} removal efficiency while burning high-sulfur coal, 30 percent NO{sub x} reductions through combustion modifications, additional NO{sub x} reductions using SNCR technology, production of marketable commercial-grade gypsum and calcium chloride by-products to minimize solid waste disposal, and zero wastewater discharge.

  10. A Nordic Project Project on High Speed Low Power Design in Sub-micron CMOS Technology for Mobile

    DEFF Research Database (Denmark)

    Olesen, Ole

    1997-01-01

    of including good off-chip components in the design by use of innovative, inexpensive package technology.To achieve a higher level of integration, the project will use a novel codesign approach to the design strategy. Rather than making specifications based on a purely architectural approach, the work uses...... a concurrent approach, where circuit designers and architecture designers co-operate on the design and specifications. This allows more circuit issues to be included in the overall architecture, hopefully resulting in an architecture with circuit blocks suited for full integration....... digital base-band processing on the same chip. Presently, only few examples of CMOS used for RF front-end circuits have been presented by academia, and so far no commercial products exist. The approach has been to do a CMOS block by block replacement of the blocks in traditional transceiver architectures...

  11. Slope excavation quality assessment and excavated volume calculation in hydraulic projects based on laser scanning technology

    Directory of Open Access Journals (Sweden)

    Chao Hu

    2015-04-01

    Full Text Available Slope excavation is one of the most crucial steps in the construction of a hydraulic project. Excavation project quality assessment and excavated volume calculation are critical in construction management. The positioning of excavation projects using traditional instruments is inefficient and may cause error. To improve the efficiency and precision of calculation and assessment, three-dimensional laser scanning technology was used for slope excavation quality assessment. An efficient data acquisition, processing, and management workflow was presented in this study. Based on the quality control indices, including the average gradient, slope toe elevation, and overbreak and underbreak, cross-sectional quality assessment and holistic quality assessment methods were proposed to assess the slope excavation quality with laser-scanned data. An algorithm was also presented to calculate the excavated volume with laser-scanned data. A field application and a laboratory experiment were carried out to verify the feasibility of these methods for excavation quality assessment and excavated volume calculation. The results show that the quality assessment indices can be obtained rapidly and accurately with design parameters and scanned data, and the results of holistic quality assessment are consistent with those of cross-sectional quality assessment. In addition, the time consumption in excavation project quality assessment with the laser scanning technology can be reduced by 70%−90%, as compared with the traditional method. The excavated volume calculated with the scanned data only slightly differs from measured data, demonstrating the applicability of the excavated volume calculation method presented in this study.

  12. Issues involved in attempting to develop independent learning in pupils working on technological projects

    Science.gov (United States)

    Barak, Moshe

    2004-02-01

    This research addresses the impact of technological projects at high school on pupils' learning. The participants were sixty low-mid achieving pupils who worked for one year on final projects for matriculation exams. Data were collected through observations of laboratory lessons, interviews with pupils and teachers, and analysis of pupils' projects and portfolios. In the modern technological laboratory, pupils experience design, construction and improvement of sophisticated systems, in a rich learning environment. From being fully dependent on their teachers, pupils might gradually develop to become more autonomous learners and creative thinkers. A three-stage model is suggested aimed to help teachers adjust their supervision approach to the pupils' conceptual development. A pupil at the 'show me' stage needs a 'direct supervision' approach; a pupil at the 'let's think together' stage needs a 'collaborative supervision' approach; a pupil at the 'trust me' stage needs a 'nondirective supervision'. In projects carried out within mandatory exams, pupils are motivated not only by internal rewards, but also by being evaluated objectively and awarded a formal credit for their achievements.

  13. MHD heat and seed recovery technology project. Tenth quarterly report, April-June 1980

    Energy Technology Data Exchange (ETDEWEB)

    Petrick, M.; Johnson, T. R.

    1980-12-01

    The MHD Heat and Seed Recovery Technology Project at Argonne National Laboratory is obtaining information for the design and operation of the steam plant downstream of the MHD channel-diffuser, and of the seed regeneration process. The project goal is to supply the engineering data required in the design of components for prototype and demonstration MHD facilities. The primary effort of the HSR Technology Project at Argonne is directed toward experimental investigations of critical problem areas, such as (1) corrosion and erosion of refractories and metal alloys; (2) NO/sub x/ behavior in the radiant boiler and secondary combustor; (3) radiant boiler design to meet the multiple requirements of steam generation, NO/sub x/ decomposition, and seed-slag separation; (4) effects of solid or liquid seed deposits on heat transfer and gas flow in the steam and air heaters; (5) formation, growth, and deposition of seed-slag particles; and (6) character of the combustion gas effluents. These investigations are performed primarily in a 2-MW test facility, the Argonne MHD Process Engineering Laboratory (AMPEL). Other project activities are related to studies of the thermochemistry of the seed-slag combustion gas system, and evaluation of seed regeneration processes. Progress is reported.

  14. Managing the ERP implementation journey - change in discourse from classical IT project to technology-driven organisational change initiative

    DEFF Research Database (Denmark)

    Kræmmergaard, Pernille; Rose, Jeremy

    2005-01-01

    In the implementation of an ERP system in a large Danish production company (here referred to as Omega), discourse surrounding the project changed appreciably during the course of the project. Drawing on recent adaptations of discourse theory, we provide a theoretical model which relates...... technological discourse to actions and outcomes. The model provides a theoretical explanation for how one dominant technological discourse in an organisation can be replaced by another. The ERP implementation at Omega was originally cast as a classical IT project (reflecting the dominant ways of thinking about...... system development and project management both in industry and academia); however, the experience of the project clearly changed the sense-making of the participants and the implementation later came to be regarded as an technology-driven organisational change initiative. The new technological discourse...

  15. Managing the ERP implementation journey - change in discourse from classical IT project to technology-driven organisational change initiative

    DEFF Research Database (Denmark)

    Kræmmergaard, Pernille; Rose, Jeremy

    In the implementation of an ERP system in a large Danish production company (here referred to as Omega), discourse surrounding the project changed appreciably during the course of the project. Drawing on recent adaptations of discourse theory, we provide a theoretical model which relates...... technological discourse to actions and outcomes. The model provides a theoretical explanation for how one dominant technological discourse in an organisation can be replaced by another. The ERP implementation at Omega was originally cast as a classical IT project (reflecting the dominant ways of thinking about...... system development and project management both in industry and academia); however, the experience of the project clearly changed the sense-making of the participants and the implementation later came to be regarded as an technology-driven organisational change initiative. The new technological discourse...

  16. Project-based learning as a facilitator to promote students’ technology competencies

    Directory of Open Access Journals (Sweden)

    Mohsen Bagheri

    2013-04-01

    Full Text Available Due to the close relationship between educational technology as a field of study on the one hand and technological progress as a fact on the other, the very nature of this field has undergone tremendous shift which has resulted in a transmogrification, changes which are evinced by the roles of educational technologist. Therefore, not only should educational technology training centers aim at transferring concepts related to this major to learners, but they should also focus on developing basic skills that students need, such as technological competencies.This article sought to examine the effects of project-based learning strategy (PoBL on students’ technology competency in a system-based education course offered in the educational technology department of Arak University in Iran. In order to achieve this end, a sample of 78 students majoring in the field of educational technology who enrolled in the system-based education course was selected. Subjects were randomly assigned to one of two groups: the experimental group (PoBL strategy and the control group (conventional teaching strategy. The educational course involved 12 sessions over the course of one semester of the 2011-2012 academic year, with each session lasting approximately 90 minutes. The technology competency questionnaire was administrated three times (i.e. pretest, post-test one, and post-test two, while the experimental group received the PoBL strategy and the control group was exposed to conventional teaching (CT methods. The results of two way repeated measure ANOVA revealed that students who were taught using Poll strategy performed better in terms of technology competency compared to students who were taught using CT strategy.

  17. In Situ Site Characterization Technologies Demonstrated at the INEEL in Decommissioning Projects

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Kelly Clyde; Meservey, Richard Harlan; Whitmill, Larry Joseph

    1999-04-01

    The United States Department of Energy (DOE)continually seeks safer, more cost-effective, and better performing technologies for decontamination and decommissioning (D&D) of nuclear facilities. The Deactivation and Decommissioning Focus Area (DDFA) of the DOE Federal Energy Technology Center (FETC) sponsors Large Scale Demonstration and Deployment Projects (LSDDPs) which are conducted at various DOE sites. The Idaho National Engineering and Environmental Laboratory (INEEL) is one of the DOE sites for demonstration of these newa and improved technologies. The INEEL needs statement defines specific needs or problems for their D&D program. One of the needs identified at the INEEL was for new or improved site characterization technologies. A variety of in-situ site characterization technologies have been demonstrated through the INEEL LSDDP. These technologies provide a safer means of characterization, improved documentation, real-time information, improved D&D schedules, and reduction in costs and radiation exposures to workers. These technologies have provided vast improvements to the D&D site characterizations. Some of these technologies include: • The Global Positioning Radiometric Scanner System for large-area, surface gamma radiation surveys • Remote underwater characterization system• Identifying heavy metals in painted surfaces and determining the alloy composition in metallic material • In-Situ Object Counting System for free release • Real-time radiological data acquisition with the Surveillance and Measurement’s sodium iodide detector • Electromagnetic radiography to locate contaminated soils. Historically, site characterization has been a slow, costly, and tedious process. However, through these demonstrations, new technologies have provided more accurate data, real-time information, and enhanced site characterization documentation. In addition, a safer work environment has been established as a result of decreasing the worker’s time

  18. Electric Ground Support Equipment Advanced Battery Technology Demonstration Project at the Ontario Airport

    Energy Technology Data Exchange (ETDEWEB)

    Tyler Gray; Jeremy Diez; Jeffrey Wishart; James Francfort

    2013-07-01

    The intent of the electric Ground Support Equipment (eGSE) demonstration is to evaluate the day-to-day vehicle performance of electric baggage tractors using two advanced battery technologies to demonstrate possible replacements for the flooded lead-acid (FLA) batteries utilized throughout the industry. These advanced battery technologies have the potential to resolve barriers to the widespread adoption of eGSE deployment. Validation testing had not previously been performed within fleet operations to determine if the performance of current advanced batteries is sufficient to withstand the duty cycle of electric baggage tractors. This report summarizes the work performed and data accumulated during this demonstration in an effort to validate the capabilities of advanced battery technologies. This report summarizes the work performed and data accumulated during this demonstration in an effort to validate the capabilities of advanced battery technologies. The demonstration project also grew the relationship with Southwest Airlines (SWA), our demonstration partner at Ontario International Airport (ONT), located in Ontario, California. The results of this study have encouraged a proposal for a future demonstration project with SWA.

  19. Discussion on the application of 3S technology in soil and water conservation project

    Science.gov (United States)

    Qin, Fen; Hu, Sujie; Wang, Yanan; Tang, Fuping

    2007-06-01

    Soil and water conservation project in the loess plateau of China is focus on improving its feasibility with new technology. This paper discussed on the application of "3S" technology in a soil and water conservation project of selected small watershed of Jingjiahe, Loess plateau. The research presents an approach to apply RUSLE to quantify soil and water loss by the help of "3S" technology, the suitability evaluation for each piece of land is implemented with the assessment indices. Finally, according to the nature condition and economic development trend, by accomplishing the analysis of the comprehensive control benefits for the small watershed, establishing rational land use pattern. Through five years construction of soil and water conservation, the controlling soil erosion area up to 2369.98 hectares, harnessed degree reaches 80.66%, the per capita net income will float up from yen 944.72 to yen 1049.75, the annual preserved area of endangered soil will be 90,000t with the efficiency increased by more than 22%, eventually the soil and water loss shall be well under control. This indicates that "3S" technology make the work more cost-effective, more efficient and more reliable taking into account the precise data which are processed in the planning.

  20. Wireless Sensor for Measuring Pump Efficiency: Small Business Voucher Project with KCF Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Fugate, David L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Energy and Transportation Science Division; Liu, Xiaobing [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Energy and Transportation Science Division; Gehl, Anthony C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Energy and Transportation Science Division; Koopmann, Gary [KCF Technologies, State College, PA (United States)

    2017-01-23

    This document is to fulfill the final report requirements for the Small Business Voucher (SBV) CRADA project with ORNL and KCF Technologies (CRADA/NFE-16-06133). Pumping systems account for nearly 20% of the world’s electrical energy demand and range from 25-50% of the energy usage in many industrial and building power plants. The energy cost is the largest element in the total cost of owning a pump (~40%). In response to a recent DOE mandate for improved pump efficiency pump manufacturers are preparing for the changes that the impending regulations will bring, including design improvements. This mandate also establishes a need for new low cost pump efficiency measurement systems. The standard industry definition of pump efficiency is the mechanical water horsepower delivered divided by the electrical horsepower input to the motor. KCF Technologies has developed a new sensor measurement technique to estimate fluid pump efficiency using a thermodynamic approach. KCF Technologies applied for a SBV grant with ORNL as the research partner. KCF needed a research partner with the proper facilities to demonstrate the efficacy of its wireless sensor unit for measuring pump efficiency. The ORNL Building Technologies Research and Integration Center (BTRIC) test resources were used to test and demonstrate the successful measurement of pump efficiency with the KCF sensor technology. KCF is now working on next steps to commercialize this sensing technology.

  1. Progress update of NASA's free-piston Stirling space power converter technology project

    Science.gov (United States)

    Dudenhoefer, James E.; Winter, Jerry M.; Alger, Donald

    1992-01-01

    A progress update is presented of the NASA LeRC Free-Piston Stirling Space Power Converter Technology Project. This work is being conducted under NASA's Civil Space Technology Initiative (CSTI). The goal of the CSTI High Capacity Power Element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space initiatives. Efforts are focused upon increasing system power output and system thermal and electric energy conversion efficiency at least five fold over current SP-100 technology, and on achieving systems that are compatible with space nuclear reactors. This paper will discuss progress toward 1050 K Stirling Space Power Converters. Fabrication is nearly completed for the 1050 K Component Test Power Converter (CTPC); results of motoring tests of the cold end (525 K), are presented. The success of these and future designs is dependent upon supporting research and technology efforts including heat pipes, bearings, superalloy joining technologies, high efficiency alternators, life and reliability testing, and predictive methodologies. This paper will compare progress in significant areas of component development from the start of the program with the Space Power Development Engine (SPDE) to the present work on CTPC.

  2. Advanced Mirror Technology Development (AMTD) project: overview and year four accomplishments

    Science.gov (United States)

    Stahl, H. Philip

    2016-07-01

    The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature toward the next Technology Readiness Level (TRL) critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics and ultra-high-contrast observations of exoplanets. Key hardware accomplishments of 2015/16 are the successful low-temperature fusion of a 1.5-meter diameter ULE mirror that is a 1/3rd scale model of a 4-meter mirror and the initiation of polishing of a 1.2-meter Extreme-Lightweight Zerodur mirror. Critical to AMTD's success is an integrated team of scientists, systems engineers, and technologists; and a science-driven systems engineering approach.

  3. Hybrid vehicle turbine engine technology support (HVTE-TS) project. 1995--1996 annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report presents a summary of technical work accomplished on the Hybrid Vehicle Turbine Engine--Technology Support (HVTE-TS) Project during calendar years 1995 and 1996. Work was performed under an initial National Aeronautics and Space Administration (NASA) contract DEN3-336. As of September 1996 the contract administration was transferred to the US Department of Energy (DoE) Chicago Operations Office, and renumbered as DE-AC02-96EE50553. The purpose of the HVTE-TS program is to develop gas turbine engine technology in support of DoE and automotive industry programs exploring the use of gas turbine generator sets in hybrid-electric automotive propulsion systems. The program focus is directed to the development of four key technologies to be applied to advanced turbogenerators for hybrid vehicles: Structural ceramic materials and processes; Low emissions combustion systems; Regenerators and seals systems; and Insulation systems and processes. 60 figs., 9 tabs.

  4. Advanced Mirror Technology Development (AMTD) Project: Overview and Year 4 Accomplishments

    Science.gov (United States)

    Stahl, H. Philip

    2016-01-01

    The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature toward the next Technology Readiness Level (TRL) critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics and ultra-high-contrast observations of exoplanets. Key hardware accomplishments of 2015/16 are the successful low-temperature fusion of a 1.5-meter diameter ULE mirror that is a 1/3rd scale model of a 4-meter mirror and the initiation of polishing of a 1.2-meter Extreme-Lightweight Zerodur mirror. Critical to AMTD's success is an integrated team of scientists, systems engineers, and technologists; and a science-driven systems engineering approach.

  5. The NutriChip project--translating technology into nutritional knowledge.

    Science.gov (United States)

    Vergères, Guy; Bogicevic, Biljana; Buri, Caroline; Carrara, Sandro; Chollet, Magali; Corbino-Giunta, Linda; Egger, Lotti; Gille, Doreen; Kopf-Bolanz, Katrin; Laederach, Kurt; Portmann, Reto; Ramadan, Qasem; Ramsden, Jeremy; Schwander, Flurina; Silacci, Paolo; Walther, Barbara; Gijs, Martin

    2012-09-01

    Advances in food transformation have dramatically increased the diversity of products on the market and, consequently, exposed consumers to a complex spectrum of bioactive nutrients whose potential risks and benefits have mostly not been confidently demonstrated. Therefore, tools are needed to efficiently screen products for selected physiological properties before they enter the market. NutriChip is an interdisciplinary modular project funded by the Swiss programme Nano-Tera, which groups scientists from several areas of research with the aim of developing analytical strategies that will enable functional screening of foods. The project focuses on postprandial inflammatory stress, which potentially contributes to the development of chronic inflammatory diseases. The first module of the NutriChip project is composed of three in vitro biochemical steps that mimic the digestion process, intestinal absorption, and subsequent modulation of immune cells by the bioavailable nutrients. The second module is a miniaturised form of the first module (gut-on-a-chip) that integrates a microfluidic-based cell co-culture system and super-resolution imaging technologies to provide a physiologically relevant fluid flow environment and allows sensitive real-time analysis of the products screened in vitro. The third module aims at validating the in vitro screening model by assessing the nutritional properties of selected food products in humans. Because of the immunomodulatory properties of milk as well as its amenability to technological transformation, dairy products have been selected as model foods. The NutriChip project reflects the opening of food and nutrition sciences to state-of-the-art technologies, a key step in the translation of transdisciplinary knowledge into nutritional advice.

  6. Night vision goggle stimulation using LCoS and DLP projection technology, which is better?

    Science.gov (United States)

    Ali, Masoud H.; Lyon, Paul; De Meerleer, Peter

    2014-06-01

    High fidelity night-vision training has become important for many of the simulation systems being procured today. The end-users of these simulation-training systems prefer using their actual night-vision goggle (NVG) headsets. This requires that the visual display system stimulate the NVGs in a realistic way. Historically NVG stimulation was done with cathode-ray tube (CRT) projectors. However, this technology became obsolete and in recent years training simulators do NVG stimulation with laser, LCoS and DLP projectors. The LCoS and DLP projection technologies have emerged as the preferred approach for the stimulation of NVGs. Both LCoS and DLP technologies have advantages and disadvantages for stimulating NVGs. LCoS projectors can have more than 5-10 times the contrast capability of DLP projectors. The larger the difference between the projected black level and the brightest object in a scene, the better the NVG stimulation effects can be. This is an advantage of LCoS technology, especially when the proper NVG wavelengths are used. Single-chip DLP projectors, even though they have much reduced contrast compared to LCoS projectors, can use LED illuminators in a sequential red-green-blue fashion to create a projected image. It is straightforward to add an extra infrared (NVG wavelength) LED into this sequential chain of LED illumination. The content of this NVG channel can be independent of the visible scene, which allows effects to be added that can compensate for the lack of contrast inherent in a DLP device. This paper will expand on the differences between LCoS and DLP projectors for stimulating NVGs and summarize the benefits of both in night-vision simulation training systems.

  7. Uracil phosphoribosyltransferase from the extreme thermoacidophilic archaebacterium Sulfolobus shibatae is an allosteric enzyme, activated by GTP and inhibited by CTP

    DEFF Research Database (Denmark)

    Linde, Lise; Jensen, Kaj Frank

    1996-01-01

    -fold without much effect on Km for the substrates. The concentration of GTP required for half-maximal activation was about 80 µM. CTP was a strong inhibitor and acted by raising the concentration of GTP needed for half-maximal activation of the enzyme. We conclude that uracil phosphoribosyltransferase......Uracil phosphoribosyltransferase, which catalyses the formation of UMP and pyrophosphate from uracil and 5-phosphoribosyl a-1-pyrophosphate (PRPP), was partly purified from the extreme thermophilic archaebacterium Sulfolobus shibatae. The enzyme required divalent metal ions for activity...... and it showed the highest activity at pH 6.4. The specific activity of the enzyme was 50-times higher at 95°C than at 37°C, but the functional half-life was short at 95°C. The activity of uracil phosphoribosyltransferase was strongly activated by GTP, which increased Vmax of the reaction by approximately 20...

  8. Report on the planning workshop on cost-effective ceramic machining. Ceramic Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Blau, P.J.

    1991-11-01

    A workshop on ``Cost Effective Ceramic Machining`` (CECM) was held at Oak Ridge Associated Universities Pollard Auditorium, Oak Ridge, Tennessee, May 1991. The purpose of this workshop was to present a preliminary project plan for industry critique and to identify specific components and cost-reduction targets for a new project on Cost Effective Ceramic Machining. The CECM project is an extension of the work on the Ceramic Technology for Advanced Heat Engines (CTAHE) Program sponsored by the Department of Energy, Office of Transportation Materials. The workshop consisted of fifteen invited papers, discussions, a survey of the attendee`s opinions, and a tour of the High Temperature Materials Laboratory at ORNL. The total number of registrants was sixty-seven, including thirty-three from industry or private sector organizations, seven from universities, three from industry groups, fourteen from DOE laboratories (including ORNL, Y-12, and Lawrence Livermore Laboratory), three from trade associations, and three from other government organizations. Forty- one survey forms, which critiqued the proposed project plan, were completed by attendees, and the results are presented in this report. Valves, cam roller followers, water pump seals, and diesel engine head plates were rated highest fro application of ceramic machining concepts to reduce cost. Coarse grinding, abrasives and wheel technology, and fine grinding were most highly rated as regards their impact on cost reduction. Specific cost-reduction targets for given parts varied greatly in the survey results and were not felt to be useful for the purposes for the CECM plan development. A range of individual comments were obtained and are listed in an appendix. As a result of the workshop and subsequent discussions, a modified project plan, different in certain aspects from the original CECM plan, has been developed.

  9. The CD27L and CTP1L endolysins targeting Clostridia contain a built-in trigger and release factor.

    Directory of Open Access Journals (Sweden)

    Matthew Dunne

    2014-07-01

    Full Text Available The bacteriophage ΦCD27 is capable of lysing Clostridium difficile, a pathogenic bacterium that is a major cause for nosocomial infection. A recombinant CD27L endolysin lyses C. difficile in vitro, and represents a promising alternative as a bactericide. To better understand the lysis mechanism, we have determined the crystal structure of an autoproteolytic fragment of the CD27L endolysin. The structure covers the C-terminal domain of the endolysin, and represents a novel fold that is identified in a number of lysins that target Clostridia bacteria. The structure indicates endolysin cleavage occurs at the stem of the linker connecting the catalytic domain with the C-terminal domain. We also solved the crystal structure of the C-terminal domain of a slow cleaving mutant of the CTP1L endolysin that targets C. tyrobutyricum. Two distinct dimerization modes are observed in the crystal structures for both endolysins, despite a sequence identity of only 22% between the domains. The dimers are validated to be present for the full length protein in solution by right angle light scattering, small angle X-ray scattering and cross-linking experiments using the cross-linking amino acid p-benzoyl-L-phenylalanine (pBpa. Mutagenesis on residues contributing to the dimer interfaces indicates that there is a link between the dimerization modes and the autocleavage mechanism. We show that for the CTP1L endolysin, there is a reduction in lysis efficiency that is proportional to the cleavage efficiency. We propose a model for endolysin triggering, where the extended dimer presents the inactive state, and a switch to the side-by-side dimer triggers the cleavage of the C-terminal domain. This leads to the release of the catalytic portion of the endolysin, enabling the efficient digestion of the bacterial cell wall.

  10. The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

    Science.gov (United States)

    Dunne, Matthew; Mertens, Haydyn D. T.; Garefalaki, Vasiliki; Jeffries, Cy M.; Thompson, Andrew; Lemke, Edward A.; Svergun, Dmitri I.; Mayer, Melinda J.; Narbad, Arjan; Meijers, Rob

    2014-01-01

    The bacteriophage ΦCD27 is capable of lysing Clostridium difficile, a pathogenic bacterium that is a major cause for nosocomial infection. A recombinant CD27L endolysin lyses C. difficile in vitro, and represents a promising alternative as a bactericide. To better understand the lysis mechanism, we have determined the crystal structure of an autoproteolytic fragment of the CD27L endolysin. The structure covers the C-terminal domain of the endolysin, and represents a novel fold that is identified in a number of lysins that target Clostridia bacteria. The structure indicates endolysin cleavage occurs at the stem of the linker connecting the catalytic domain with the C-terminal domain. We also solved the crystal structure of the C-terminal domain of a slow cleaving mutant of the CTP1L endolysin that targets C. tyrobutyricum. Two distinct dimerization modes are observed in the crystal structures for both endolysins, despite a sequence identity of only 22% between the domains. The dimers are validated to be present for the full length protein in solution by right angle light scattering, small angle X-ray scattering and cross-linking experiments using the cross-linking amino acid p-benzoyl-L-phenylalanine (pBpa). Mutagenesis on residues contributing to the dimer interfaces indicates that there is a link between the dimerization modes and the autocleavage mechanism. We show that for the CTP1L endolysin, there is a reduction in lysis efficiency that is proportional to the cleavage efficiency. We propose a model for endolysin triggering, where the extended dimer presents the inactive state, and a switch to the side-by-side dimer triggers the cleavage of the C-terminal domain. This leads to the release of the catalytic portion of the endolysin, enabling the efficient digestion of the bacterial cell wall. PMID:25058163

  11. PVC esaslı CTP kesme atığı dolgulu malzemelerin termal özelliklerinin incelenmesi

    Directory of Open Access Journals (Sweden)

    Arzu Özüyağlı

    2016-08-01

    Full Text Available Bu çalışmada, PVC üretiminde kullanılan CaCO3 dolgu malzemesi yerine, sanayi atığı kullanılması sonucu termal özelliklerdeki değişim araştırılmıştır. Kullanılan sanayi atığı CTP boru üretiminden sulu kesim sırasında çıkmakta ve SiO2, cam elyaf ve polyester reçine içermektedir. Sulu çamur halinde filtre presten çıkan atık fabrikadan alındıktan sonra kurutma ve eleme işlemleri uygulanarak toz formuna getirilmiştir. Numuneler PVC, CTP atık tozu ve prosese yardımcı maddeler mikserde karıştırılarak ekstrüzyon yöntemi ile profil şeklinde üretilmiştir. Atık toz PVC’ye oranla ağırlıkça %5-%70 oranlarında dolgu malzemesi olarak kullanılmıştır. Kalsit (CaCO3 katkılı ve katkısız PVC numuneleri de benzer proses parametreleri kullanılarak üretilmiştir. Üretilen numuneler, seramik krozeler kullanılarak DTA-TG analizleri yapılmıştır.

  12. Fermilab Project X nuclear energy application: Accelerator, spallation target and transmutation technology demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Gohar, Yousry; /Argonne; Johnson, David; Johnson, Todd; Mishra, Shekhar; /Fermilab

    2011-04-01

    The recent paper 'Accelerator and Target Technology for Accelerator Driven Transmutation and Energy Production' and report 'Accelerators for America's Future' have endorsed the idea that the next generation particle accelerators would enable technological breakthrough needed for nuclear energy applications, including transmutation of waste. In the Fall of 2009 Fermilab sponsored a workshop on Application of High Intensity Proton Accelerators to explore in detail the use of the Superconducting Radio Frequency (SRF) accelerator technology for Nuclear Energy Applications. High intensity Continuous Wave (CW) beam from the Superconducting Radio Frequency (SRF) Linac (Project-X) at beam energy between 1-2 GeV will provide an unprecedented experimental and demonstration facility in the United States for much needed nuclear energy Research and Development. We propose to carry out an experimental program to demonstrate the reliability of the accelerator technology, Lead-Bismuth spallation target technology and a transmutation experiment of spent nuclear fuel. We also suggest that this facility could be used for other Nuclear Energy applications.

  13. Sustainable energy for cashew production chain using innovative clean technology project developments

    Energy Technology Data Exchange (ETDEWEB)

    Pannir Selvam, P.V.; Nandenha, Julio; Santiago, Brunno Henrique de Souza; Silva, Rosalia Tatiane da [Universidade Federal do Rio Grande do Norte (GPEC/DEQ/UFRN), Lagoa Nova, RN (Brazil). Dept. de Engenharia Quimica. Grupo de Pesquisa em Engenharia de Custos e Processos], e-mail: pannirbr@gmail.com

    2006-07-01

    The main objective is to develop a new process synthesis based on the residual biomass waste for the energy production applied to the fruit processing plant with co-production of hot, cold thermal energy using biogas from the wood biomass and animal wastes. After carried out the bibliographical research about the current state of art technology, an engineering project had been developed with the use of the software Super Pro Designer V 4.9. Some simulations of processes of the fast pyrolysis, gasification, bio digestion, generation of energy have been realized including the system integration of energy production as innovation of the present work. Three cases study have been developed: first, the current process of conventional energy using combustion, another one using combined pyrolysis and gasification, and the last one with bio digestion for combined power, heat and chilling. The results about the project investment and the cost analysis, economic viability and cash balance were obtained using software Orc 2004. Several techno-economic parameters of the selected cases study involving process innovation were obtained and compared, where a better energy and materials utilization were observed in relation to conventional process. This project which is still in development phase, involves small scale energy integrated system design. The energy and the process integration cashew fruit production chain, based on the clean technology process design, has enable significant improvement in terms of economic and environmental using optimal system configurations with viability and sustainability. (author)

  14. Hydrocarbon Conversion to Valuable Products from GTP to BTP and CTP

    Institute of Scientific and Technical Information of China (English)

    Theo H Fleisch

    2004-01-01

    @@ The world has an abundant supply of low cost natural gas in remote locations. The monetization of these stranded gas resources requires new technologies and markets. GTP (Gas To Products ) technologies emerge as options to efficiently convert this resource into clean, high value fuels and chemicals.

  15. Utility-Scale Concentrating Solar Power and Photovoltaic Projects: A Technology and Market Overview

    Energy Technology Data Exchange (ETDEWEB)

    Mendelsohn, M.; Lowder, T.; Canavan, B.

    2012-04-01

    Over the last several years, solar energy technologies have been, or are in the process of being, deployed at unprecedented levels. A critical recent development, resulting from the massive scale of projects in progress or recently completed, is having the power sold directly to electric utilities. Such 'utility-scale' systems offer the opportunity to deploy solar technologies far faster than the traditional 'behind-the-meter' projects designed to offset retail load. Moreover, these systems have employed significant economies of scale during construction and operation, attracting financial capital, which in turn can reduce the delivered cost of power. This report is a summary of the current U.S. utility-scale solar state-of-the-market and development pipeline. Utility-scale solar energy systems are generally categorized as one of two basic designs: concentrating solar power (CSP) and photovoltaic (PV). CSP systems can be further delineated into four commercially available technologies: parabolic trough, central receiver (CR), parabolic dish, and linear Fresnel reflector. CSP systems can also be categorized as hybrid, which combine a solar-based system (generally parabolic trough, CR, or linear Fresnel) and a fossil fuel energy system to produce electric power or steam.

  16. Experience in Use of Project Method During Technology Lessons in Secondary Schools of the USA

    Directory of Open Access Journals (Sweden)

    Sheludko Inna

    2015-08-01

    Full Text Available The article examines the opportunities and prospects for the use of experience of project method during “technology lessons” in US secondary schools, since the value of project technology implementation experience into the educational process in the USA for ensuring holistic development of children, preparing them for adult life, in which they will be able to realize themselves and benefit society, seems undeniable to improve the quality of Ukrainian education. Its structure and content accorded with national traditions and European standards have made possible the success of educational components of American secondary school. This encourages national scientists and teachers to identify and scientifically justify the ways how to use scientific achievements of American educational system. Given the above, we have defined the following objectives: to summarize progressive trends and innovative approaches to the quality training of students in national secondary schools; to formulate guidelines that will improve the efficiency of training Ukrainian students during technology lessons and as a result, will provide the successful integration of the national education system into the European educational space.

  17. ASEAN--USAID Buildings Energy Conservation Project final report. Volume 2, Technology

    Energy Technology Data Exchange (ETDEWEB)

    Levine, M.D.; Busch, J.F. [eds.

    1992-06-01

    This volume reports on research in the area of energy conservation technology applied to commercial buildings in the Association of Southeast Asian Nations (ASEAN) region. Unlike Volume I of this series, this volume is a compilation of original technical papers prepared by different authors in the project. In this regard, this volume is much like a technical journal. The papers that follow report on research conducted by both US and ASEAN researchers. The authors representing Indonesia, Malaysia, Philippines, and Thailand, come from a range of positions in the energy arena, including government energy agencies, electric utilities, and universities. As such, they account for a wide range of perspectives on energy problems and the role that technology can play in solving them. This volume is about using energy more intelligently. In some cases, the effort is towards the use of more advanced technologies, such as low-emittance coatings on window glass, thermal energy storage, or cogeneration. In others, the emphasis is towards reclaiming traditional techniques for rendering energy services, but in new contexts such as lighting office buildings with natural light, or cooling buildings of all types with natural ventilation. Used in its broadest sense, the term ``technology`` encompasses all of the topics addressed in this volume. Along with the more customary associations of technology, such as advanced materials and equipment and the analysis of their performance, this volume treats design concepts and techniques, analysis of ``secondary`` impacts from applying technologies (i.e., unintended impacts, or impacts on parties not directly involved in the purchase and use of the technology), and the collection of primary data used for conducting technical analyses.

  18. Managing the ERP implementation journey - change in discourse from classical IT project to technology-driven organisational change initiative

    OpenAIRE

    Kræmmergaard, Pernille; Rose, Jeremy

    2006-01-01

    In the implementation of an ERP system in a large Danish production company (here referred to as Omega), discourse surrounding the project changed appreciably during the course of the project. Drawing on recent adaptations of discourse theory, we provide a theoretical model which relates technological discourse to actions and outcomes. The model provides a theoretical explanation for how one dominant technological discourse in an organisation can be replaced by another. The ERP implementation...

  19. Development of an Improved Process for Installation Projects of High Technology Manufacturing Equipment

    Energy Technology Data Exchange (ETDEWEB)

    Quintana, Sarah V. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-04-30

    High technology manufacturing equipment is utilized at Los Alamos National Laboratory (LANL) to support nuclear missions. This is undertaken from concept initiation where equipment is designed and then taken through several review phases, working closely with system engineers (SEs) responsible for each of the affected systems or involved disciplines (from gasses to HVAC to structural, etc.). After the design is finalized it moves to procurement and custom fabrication of the equipment and equipment installation, including all of the paperwork involved. Not only are the engineering and manufacturing aspects important, but also the scheduling, financial forecasting, and planning portions that take place initially and are sometimes modified as the project progresses should requirements, changes or additions become necessary. The process required to complete a project of this type, including equipment installation, is unique and involves numerous steps to complete. These processes can be improved and recent work on the Direct Current Arc (DC Arc) Glovebox Design, Fabrication and Installation Project provides an opportunity to identify some important lessons learned (LL) that can be implemented in the future for continued project improvement and success.

  20. FY16 Safeguards Technology Cart-Portable Mass Spectrometer Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Cyril V. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Whitten, William B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-02-01

    The Oak Ridge National Laboratory project for the Next Generation Safeguards Initiative Safeguards Technology Development Subprogram has been involved in the development of a cart portable mass spectrometer based on a Thermo ITQ ion trap mass spectrometer (referred to simply as the ITQ) for the field analysis of 235U/238U ratios in UF6. A recent discovery of the project was that combining CO2 with UF6 and introducing the mixture to the mass spectrometer (MS) appeared to increase the ionization efficiency and, thus, reduce the amount of UF6 needed for an analysis while also reducing the corrosive effects of the sample. However, initial experimentation indicated that mixing parameters should be closely controlled to ensure reproducible results. To this end, a sample manifold (SM) that would ensure the precise mixing of UF6 and CO2 was designed and constructed. A number of experiments were outlined and conducted to determine optimum MS and SM conditions which would provide the most stable isotope ratio analysis. The principal objective of the project was to provide a retrofit ITQ mass spectrometer operating with a SM capable of achieving a variation in precision of less than 1% over 1 hour of sampling. This goal was achieved by project end with a variation in precision of 0.5 to 0.8% over 1 hour of sampling.