The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti
Pini, Francesco; Frage, Benjamin; Ferri, Lorenzo; De Nisco, Nicole J.; Mohapatra, Saswat S.; Taddei, Lucilla; Fioravanti, Antonella; Dewitte, Frederique; Galardini, Marco; Brilli, Matteo; Villeret, Vincent; Bazzicalupo, Marco; Mengoni, Alessio; Walker, Graham C.; Becker, Anke; Biondi, Emanuele G.
2013-01-01
SUMMARY Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with higher membrane permeability. In Caulobacter crescentus, a related alphaproteobacterium, the principal cell cycle regulator, CtrA, is inhibited by the phosphorylated response regulator DivK. The phosphorylation of DivK depends on the histidine kinase DivJ, while PleC is the principal phosphatase for DivK. Despite the importance of the DivJ in C. crescentus, the mechanistic role of this kinase has never been elucidated in other Alphaproteobacteria. We show here that the histidine kinases DivJ together with CbrA and PleC participate in a complex phosphorylation system of the essential response regulator DivK in S. meliloti. In particular, DivJ and CbrA are involved in DivK phosphorylation and in turn CtrA inactivation, thereby controlling correct cell cycle progression and the integrity of the cell envelope. In contrast, the essential PleC presumably acts as a phosphatase of DivK. Interestingly, we found that a DivJ mutant is able to elicit nodules and enter plant cells, but fails to establish an effective symbiosis suggesting that proper envelope and/or low CtrA levels are required for symbiosis. PMID:23909720
International Nuclear Information System (INIS)
Ahmed, A.; Sabri, A.N.
2004-01-01
In B.subtilis, cell division is controlled by div-genes which have been mapped on its circular chromosome. In the present work, div-mutant strains 1A316(div II), 1A317 and 1A318 (div I) were studied. These strains exhibited temperature sensitive cell division mutations. Colony morphology, cell morphology, staining behavior, growth rate and protein content of PY79 (wild type) and div-mutant strains (1A316, 1A317, 1A318) was studied at different temperatures ( 25 deg. Centi grade and 42 deg. with varying incubation periods(4, 16, 24, 48, 72,96 hrs). div-mutants differ from wild type (PY79) in colony morphology. Colony margin in PY79 was entire while in the div strains it is undulate. Staining behavior of cells as well as cell morphology i.e., cell size, cell types, formation of filaments/minicells were affected by high temperature. At higher temperature (42 deg. Centi grade), div-mutants undergo more severe lysis and degeneration as compare to wild type (PY79). Defective spores were produced by div-mutants at 25 deg. Centi grade and 42 deg. Centi grade. Tetrazolium overlay test was performed at 37 deg. Centi grade and 42 deg. Centi grade to check the spore germination ability of wild type and div-mutants. In 1A318, defective spores were produced at 37 deg. Centi grade, div-mutant was checked after 24 and 96 hrs at different temperatures (25, 37 and 42 deg. Centi grade). At all temperatures protein content were more in PY79 as compare to div-mutants. Also at 25 and 42 deg. Centi grade, protein content was more as compare to 37 deg. Centi grade. Protein contents was reduced at sporulation stages. Thus cell division mutations affect cell morphology, sporulation and germination processes in B.subtilis and thus are multifaceted mutations. (author)
Cleareye In-Ground and In-Concrete DIV Inspections: FY11 Final Report
Energy Technology Data Exchange (ETDEWEB)
Braatz, Brett G.; Tedeschi, Jonathan R.; Denslow, Kayte M.; Morra, Marino; Knopik, Clint D.; Severtsen, Ronald H.; Jones, Anthony M.; Lechelt, Wayne M.; McMakin, Douglas L.; Good, Morris S.; Sorensen, Jerry B.; Hall, Thomas E.
2012-01-23
This report summarizes the results of a series of feasibility testing studies for in-ground and in-concrete imaging/detection technologies including radar imaging and acoustic time-of flight method. The objectives of this project are: (1) Design Information Verification (DIV) Tools for In-Concrete Inspections - To determine the feasibility of using holographic radar imaging (HRI), radar imaging, and acoustic time-of-flight (TOF) non-destructive evaluation technologies to detect, locate and identify pipes and voids embedded in standard-density and high-density concrete walls that typify those the IAEA will need to verify during field inspections; (2) DIV Tools for In-Ground Inspections - To determine the feasibility of using HRI and radar imaging non-destructive evaluation technologies to detect, locate, and identify objects buried at various depths made of various materials (metal, plastic, wood, and concrete) and representing geometries that typify those the IAEA will need to verify during field inspections; and (3) Based on the results of the studies, recommend the next steps needed to realize fieldable tools for in-concrete and in-ground inspections (including detection of deeply buried polyvinyl chloride [PVC] pipes) that employ the technologies shown to be feasible.
Phyto-gegographycal analysis of Divčibare
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Popović Ivana
2005-01-01
Full Text Available The aim of phytogeographical analysis is to determine the plant species origin, genesis and migrations. The study results contribute to the knowledge of phytogeographical classification of the particular regions. Different chorions, by their effects, determine the flora structure and composition. The aim of the floristic research of Divčibare was to identify the diversity of flora in this region, i.e., in a wider sense, the diversity of flora in Serbia. Phytogeographical analysis was based on floristic research. The identified plant species were classified into the corresponding floral elements, area groups and area types. The data on diversity and the degree of representation in the flora of Divčibare were obtained based on the percentage of each area type. It was concluded that the flora of Divčibare has a transitional, Central European-Mediterranean-Pontic character.
Wright-Fisher diffusion bridges.
Griffiths, Robert C; Jenkins, Paul A; Spanò, Dario
2017-10-06
The trajectory of the frequency of an allele which begins at x at time 0 and is known to have frequency z at time T can be modelled by the bridge process of the Wright-Fisher diffusion. Bridges when x=z=0 are particularly interesting because they model the trajectory of the frequency of an allele which appears at a time, then is lost by random drift or mutation after a time T. The coalescent genealogy back in time of a population in a neutral Wright-Fisher diffusion process is well understood. In this paper we obtain a new interpretation of the coalescent genealogy of the population in a bridge from a time t∈(0,T). In a bridge with allele frequencies of 0 at times 0 and T the coalescence structure is that the population coalesces in two directions from t to 0 and t to T such that there is just one lineage of the allele under consideration at times 0 and T. The genealogy in Wright-Fisher diffusion bridges with selection is more complex than in the neutral model, but still with the property of the population branching and coalescing in two directions from time t∈(0,T). The density of the frequency of an allele at time t is expressed in a way that shows coalescence in the two directions. A new algorithm for exact simulation of a neutral Wright-Fisher bridge is derived. This follows from knowing the density of the frequency in a bridge and exact simulation from the Wright-Fisher diffusion. The genealogy of the neutral Wright-Fisher bridge is also modelled by branching Pólya urns, extending a representation in a Wright-Fisher diffusion. This is a new very interesting representation that relates Wright-Fisher bridges to classical urn models in a Bayesian setting. Copyright © 2017 Elsevier Inc. All rights reserved.
SUSTAINABLE ORIGINS IN ARCHITECTURE OF FRANK LLOYD WRIGHT
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Martina Zbašnik-Senegačnik
2012-10-01
Full Text Available Frank Lloyd Wright is the greatest American architect and oneof the greatest architects the world. His career began at theend of the 19th century, during the great architectural boom inChicago, under the mentorship of Louis Henry Sullivan, fromwhom he adopted and then perfected the concepts of organicarchitecture and the Prairie house. During the Depressionyears, Wright developed a cheaper and simpler variant of thePrairie house: the Usonian house.Wright's architecture is characterised by an entirely newapproach to building design, particularly the design of houses.He reduced the number of rooms by combining their functionsin a large living space with a central fireplace. He used largeglazed areas to connect the external environment of the housewith the interior. The natural environment of the prairie wasthe inspiration for the horizontal lines that characterised hisarchitecture. His buildings are low in height, close to humanscale and with a great feeling for the natural setting in whichthey are built. He selected materials from the surroundingarea and the principal decoration of his architecture was thenatural structure of the material.The paper presents the ideas of organic architecture, thePrairie house, the Usonian house, along with the best examplesof Wright's architecture and the criteria he employed in theselection of materials and construction technologies. Theenvironmental aspect of his philosophy of the use of materialsis considered in the discussion section.Wright may be considered a pioneer of sustainable architecture.
Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains.
Hsu, Eric J; Zhu, Wandi; Schubert, Angela R; Voelker, Taylor; Varga, Zoltan; Silva, Jonathan R
2017-03-06
Functional eukaryotic voltage-gated Na + (Na V ) channels comprise four domains (DI-DIV), each containing six membrane-spanning segments (S1-S6). Voltage sensing is accomplished by the first four membrane-spanning segments (S1-S4), which together form a voltage-sensing domain (VSD). A critical Na V channel gating process, inactivation, has previously been linked to activation of the VSDs in DIII and DIV. Here, we probe this interaction by using voltage-clamp fluorometry to observe VSD kinetics in the presence of mutations at locations that have been shown to impair Na V channel inactivation. These locations include the DIII-DIV linker, the DIII S4-S5 linker, and the DIV S4-S5 linker. Our results show that, within the 10-ms timeframe of fast inactivation, the DIV-VSD is the primary regulator of inactivation. However, after longer 100-ms pulses, the DIII-DIV linker slows DIII-VSD deactivation, and the rate of DIII deactivation correlates strongly with the rate of recovery from inactivation. Our results imply that, over the course of an action potential, DIV-VSDs regulate the onset of fast inactivation while DIII-VSDs determine its recovery. © 2017 Hsu et al.
SecA is required for membrane targeting of the cell division protein DivIVA in vivo
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Sven eHalbedel
2014-02-01
Full Text Available The conserved protein DivIVA is involved in different morphogenetic processes in Gram-positive bacteria. In Bacillus subtilis, the protein localises to the cell division site and cell poles, and functions as a scaffold for proteins that regulate division site selection, and for proteins that are required for sporulation. To identify other proteins that bind to DivIVA, we performed an in vivo cross-linking experiment. A possible candidate that emerged was the secretion motor ATPase SecA. SecA mutants have been described that inhibit sporulation, and since DivIVA is necessary for sporulation, we examined the localisation of DivIVA in these mutants. Surprisingly, DivIVA was delocalised, suggesting that SecA is required for DivIVA targeting. To further corroborate this, we performed SecA depletion and inhibition experiments, which provided further indications that DivIVA localisation depends on SecA. Cell fractionation experiments showed that SecA is important for binding of DivIVA to the cell membrane. This was unexpected since DivIVA does not contain a signal sequence, and is able to bind to artificial lipid membranes in vitro without support of other proteins. SecA is required for protein secretion and membrane insertion, and therefore its role in DivIVA localisation is likely indirect. Possible alternative roles of SecA in DivIVA folding and/or targeting are discussed.
76 FR 79019 - Wright Brothers Day, 2011
2011-12-20
... with earnings from their bicycle shop, gathering data on wing shape using a home-built wind tunnel and... the Wright brothers over a century ago. To reaffirm our role as the engine that drives science and..., must we press onward, exploring new frontiers of science, technology, and imagination in pursuit of a...
Parallel Auxiliary Space AMG Solver for $H(div)$ Problems
Energy Technology Data Exchange (ETDEWEB)
Kolev, Tzanio V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2012-12-18
We present a family of scalable preconditioners for matrices arising in the discretization of $H(div)$ problems using the lowest order Raviart--Thomas finite elements. Our approach belongs to the class of “auxiliary space''--based methods and requires only the finite element stiffness matrix plus some minimal additional discretization information about the topology and orientation of mesh entities. Also, we provide a detailed algebraic description of the theory, parallel implementation, and different variants of this parallel auxiliary space divergence solver (ADS) and discuss its relations to the Hiptmair--Xu (HX) auxiliary space decomposition of $H(div)$ [SIAM J. Numer. Anal., 45 (2007), pp. 2483--2509] and to the auxiliary space Maxwell solver AMS [J. Comput. Math., 27 (2009), pp. 604--623]. Finally, an extensive set of numerical experiments demonstrates the robustness and scalability of our implementation on large-scale $H(div)$ problems with large jumps in the material coefficients.
Parallel Solver for H(div) Problems Using Hybridization and AMG
Energy Technology Data Exchange (ETDEWEB)
Lee, Chak S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2016-01-15
In this paper, a scalable parallel solver is proposed for H(div) problems discretized by arbitrary order finite elements on general unstructured meshes. The solver is based on hybridization and algebraic multigrid (AMG). Unlike some previously studied H(div) solvers, the hybridization solver does not require discrete curl and gradient operators as additional input from the user. Instead, only some element information is needed in the construction of the solver. The hybridization results in a H1-equivalent symmetric positive definite system, which is then rescaled and solved by AMG solvers designed for H1 problems. Weak and strong scaling of the method are examined through several numerical tests. Our numerical results show that the proposed solver provides a promising alternative to ADS, a state-of-the-art solver [12], for H(div) problems. In fact, it outperforms ADS for higher order elements.
77 FR 75503 - Wright Brothers Day, 2012
2012-12-20
... Wright pursued their lifelong dream. Like so many Americans before and after them, these two men achieved... stay ahead of the curve and keep America moving forward. With their game-changing feat, the Wright...
Richrd Wright: a reluctant comrade
Torres, Stela
1982-01-01
Richard Wright's works have often been disregarded by scholars as a mere form of propaganda in which the writer pleads the cause of the Communist Party. We must admit, however, that although Wright poses questions in his novels and short stories which are political by nature (for instance, how can the black man as an oppressed, divided, unauthentic being participate effectively in his struggle for liberation from a racist society?), the alternatives he envisages seem quite unorthodox when con...
2004-01-01
The wind tunnel test results have been published in the literature as summarized at the end of this report. As part of the education program, an introduction to engineering course module was designed and tested on 80 freshman engineering students at Old Dominion University. The five-week module required that five-person teams design, build and fly a radio-controlled airplane using only the wind tunnel data developed by the Wright brothers in 1902. That module is described in Sparks and Ash (2001). The Principal Investigator has co-authored one dozen publications resulting from this research, as listed at the end of this report. The Principal Investigator has given fourteen lectures on the Wright brother testing program and has appeared in two documentary television programs (summarized at the end of this report). Speaking invitations have continued since the completion of the project.
Directory of Open Access Journals (Sweden)
Prahathees Eswaramoorthy
2014-08-01
Full Text Available Sporulation in the bacterium Bacillus subtilis is a developmental program in which a progenitor cell differentiates into two different cell types, the smaller of which eventually becomes a dormant cell called a spore. The process begins with an asymmetric cell division event, followed by the activation of a transcription factor, σF, specifically in the smaller cell. Here, we show that the structural protein DivIVA localizes to the polar septum during sporulation and is required for asymmetric division and the compartment-specific activation of σF. Both events are known to require a protein called SpoIIE, which also localizes to the polar septum. We show that DivIVA copurifies with SpoIIE and that DivIVA may anchor SpoIIE briefly to the assembling polar septum before SpoIIE is subsequently released into the forespore membrane and recaptured at the polar septum. Finally, using super-resolution microscopy, we demonstrate that DivIVA and SpoIIE ultimately display a biased localization on the side of the polar septum that faces the smaller compartment in which σF is activated.
Probing into the Secret of the Chinese Air Force.
1983-11-30
Ri35 968 PROBING INTO THE SECRET OF THE CHINESE AIR FOREE(IJ 1/2 FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON RFB OH 9 38 NOV 83 FTD-ID(,RS)T 1088 3...FOREIGN TECHNOLOGY DIVISION. PROBING INTO THE SECRET OF THE CHINESE AIRFORCE CL1 Approved for public re.lease; distribution unlimited C=)X ~ EET...MICROFICHE NR: FTD-83-C-001469 PROBING INTO THE SECRET OF THE CHINESE AIRFORCE -" -English pages: 111 Source: Enclosure to IR 6 842 0088 83-Booklet
Frank Lloyd Wright in the Soviet Union
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Brian A. Spencer
2017-12-01
Full Text Available In 1937 the First All-Union Congress of Soviet Architects was held in Moscow. The congress brought architects from all areas of the Soviet Union. Under the auspices of Vsesoiuvnoe Obshchestvo Kul'turnoi Sviazi s zagranitsei (VOKS it invited international architects from Europe and North and South America. The Organizing Committee of the Union of Soviet Architects invited Frank Lloyd Wright from the United States. Frank Lloyd Wright presented his philosophy and exhibited his work, specifically his designs for the weekend home for E. J. Kaufmann "Fallingwater" and the drawings for the S.C. Johnson Administration. Frank Lloyd Wright's presentation did not focus heavily on the architecture but, rather the spirit of the Russian and Soviet vision.
Sir Almroth Wright: pioneer immunologist.
Ellis, Harold
2011-03-01
This year marks the 150th anniversary of the birth of Almroth Edward Wright, whose pioneer work in immunology saved countless lives, especially in the First World War, but whose name and work are all but forgotten today. Wright was born in 1861 in Middleton Tyas, Yorkshire, where his father, an Irish protestant and considerable Hebrew scholar, was the minister. Almroth's Swedish mother, the daughter of NW Almroth, governor of the mint in Stockholm, was responsible for his unusual first name. She had the rare distinction of having served as a nurse with Florence Nightingale in the hospital at Scutari in the Crimean War.
Lee, Robert E; Young, Robert H; Castleman, Benjamin
2002-01-01
James Homer Wright (1869-1928), the eldest son of a Pittsburgh glass merchant, was educated in Baltimore and practiced pathology in Boston from 1893 until his death in 1928. In 1896, when not quite 27 years old, he assumed directorship of the newly founded Pathology Laboratory at the Massachusetts General Hospital, a post he held for the next 30 years. He is remembered eponymously by the blood cell stain that bears his name and the Homer Wright pseudorosettes of neuroblastoma, but he made many additional contributions to pathology. These include the following: determination of the cellular lineage of multiple myeloma, identification of the megakaryocyte as the cell of origin of blood platelets, recognition of the cell of origin of the neuroblastoma, demonstration of spirochetes in syphilitic aneurysms of the aorta, and clarification of misconceptions about actinomycosis. Additionally, Wright coauthored, with Dr. Frank B. Mallory, the book Pathological Technique, which was a staple of laboratories for >40 years and exemplifies Wright's wide-ranging interests in, and contributions to, practical aspects of pathology including staining, culture and frozen section techniques, photography, and development of the rotary microtome. He received Honorary Doctor of Science Degrees from Harvard University, the University of Maryland (his alma mater), and the University of Missouri. He was the recipient of the Gross prize in 1905 for his publication on actinomycosis and the Boylston Medical Prize in 1908 for his discovery of the origin of platelets, and he was inducted into the American Academy of Arts and Sciences in 1915. Although shy and somewhat austere in the workplace, a different side was shown by his anonymously sending flowers to a young Norwegian opera singer whom he subsequently married. The pathology laboratories of the Massachusetts General Hospital were named the "James Homer Wright Pathology Laboratories" in 1956. Today James Homer Wright is remembered and
Spectral mimetic least-squares method for div-curl systems
Gerritsma, Marc; Palha, Artur; Lirkov, I.; Margenov, S.
2018-01-01
In this paper the spectral mimetic least-squares method is applied to a two-dimensional div-curl system. A test problem is solved on orthogonal and curvilinear meshes and both h- and p-convergence results are presented. The resulting solutions will be pointwise divergence-free for these test
Because Everyone Has a Story to Tell: Interview with Andrew Wright
Floris, Flora Debora
2016-01-01
This article presents an interview with Andrew Wright, a widely recognized author, illustrator, storyteller, and teacher trainer. Wright has published many ELT books, authored six "Spellbinder" graded readers (1992-1994), and a collection of short stories. As a teacher trainer, Wright worked extensively with both teachers and students in…
Design information verification (DIV) of closed geological repositories (SAGOR activity 3c)
International Nuclear Information System (INIS)
Myatt, J.
1998-02-01
Following IAEA Advisory and Consultants Group meetings in September 1988 and in May 1991 respectively an IAEA multi-national Support Programme Task was initiated to consider the 'Development of Safeguards for Final Disposal of Spent Fuel in Geological Repositories' (SAGOR). A 'Technical Coordination Committee' (TCC) was set up with invited representatives from those Member State Support Programmes wishing to be involved. The joint programme, through the TCC, was given the task of studying the safeguards requirements in: conditioning plant (where the spent fuel is prepared for transfer to the repository); operating repositories (i.e. those in which the fuel is being emplaced); closed repositories. At the first meeting of the TCC in Washington in July 1994 the UK undertook to provide a study of the Design Information Verification (DIV) required in all three areas. For this activity the requirements, techniques and procedures for the Design Information Verification (DIV) of closed repositories have been considered. In completing the study the findings reported for activities 1b/c and 2c (descriptions of a Model Repository and Potential Diversion Paths, respectively) have been used in formulating any conclusions reached. It is also debatable as to whether this activity is strictly speaking DIV or is one of surveillance. As undeclared access can only be made to the emplacement areas of the repository by altering the physical makeup of the surrounding area; i.e. physically changing the 'design' of the surrounding area, however, this is deemed to be DIV. Although the techniques used appear to be those of surveillance they are being applied in this case as the tools of DIV. As with any facility there are a number of stages in its lifetime. For the purposes of this report the operating life of a repository is defined as being the time from inception to when it is finally decommissioned and sealed with the ground surface returned to being a green field. The repository is
Women in History--Marian Wright Edelman: Crusader for Civil and Children's Rights
Mills, Shirley J.
2006-01-01
This article profiles Marian Wright Edelman, a crusader for civil and children's rights. She was born June 6, 1939, at a time when prejudice and segregation were the norm. The Wright family lived in a small, southern town of Bennetsville, South Carolina, where Marian was the youngest of five children. Her father, the Reverend Arthur Jerome Wright,…
La arquitectura tardía de Frank Lloyd Wright, el primer maestro moderno
González Capitel, Antón
1996-01-01
1. La arquitectura tardía de Frank Lloyd Wright, el primer maestro moderno l. l. Un Wright renovado. Talleres y residencias l. l. l. Nuevas casas de Wright en su segunda «edad de oro»: un neoplasticismo orgánico en la casa de la Cascada l. l. 2. Geometrías y disposiciones alternativas l. 2. Arquitectura y ciudad orgánicas 1. 2. 1. El desarrollo de la arquitectura orgánica 1. 3. Arquitecturas relacionadas con la de Frank Lloyd Wright entre los emigrados europeos: Schindler y...
Modern housing design: prefabricated and modular design in Frank Lloyd Wright's architecture
Directory of Open Access Journals (Sweden)
Ana Tagliari
2011-12-01
Full Text Available This paper investigates the residential architecture of Frank Lloyd Wright, especially the designs which were conceived from an idea of prefabricated, modular, low-cost, and high-scale construction. Wright's organic designs originated from a material-based grid, which at the same time organized and provided freedom to create spaces and forms. This study reviews Wright's work, from his first Midwest designs that relied on brick, through an intermediary phase in California when he made intense use of concrete blocks, until his last phase, the usonian houses, which featured wood paneling. During his early career, the concept and the methodology of Wright's ideas greatly contributed to a better understanding of his architecture, his apprentices and his followers. The economy and rationalization found in the projects reviewed are of great importance as the analysis of historical proposals helps us understand the topic in question.
Energy Technology Data Exchange (ETDEWEB)
Borbulevych, Oleg Y.; Plumley, Joshua A.; Martin, Roger I. [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States); Merz, Kenneth M. Jr [University of Florida, Gainesville, Florida (United States); Westerhoff, Lance M., E-mail: lance@quantumbioinc.com [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States)
2014-05-01
Semiempirical quantum-chemical X-ray macromolecular refinement using the program DivCon integrated with PHENIX is described. Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein–ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.
75 FR 80669 - Wright Brothers Day, 2010
2010-12-22
... curious minds eager to transform and advance the world around them. Just as the Wright brothers... making great progress in ushering in a new commercial space industry that can help boost our economy...
Looking and Learning: The Solomon R. Guggenheim Museum, Frank Lloyd Wright
Vatsky, Sharon
2007-01-01
Frank Lloyd Wright was born and raised on the farmlands of Wisconsin. His mother had a vision that her son would become a great architect. Wright was raised with strong guiding principles, a love of nature, a belief in the unity of all things, and a respect for discipline and hard work. He created the philosophy of "organic architecture," which…
Intertwining of the Wright-Fisher diffusion
Czech Academy of Sciences Publication Activity Database
Hudec, Tobiáš
2017-01-01
Roč. 53, č. 4 (2017), s. 730-746 ISSN 0023-5954 Institutional support: RVO:67985556 Keywords : Intertwining of Markov processes * Wright-Fisher diffusion * pure birth process Subject RIV: BA - General Mathematics OBOR OECD: Statistics and probability Impact factor: 0.379, year: 2016 http://library.utia.cas.cz/separaty/2017/SI/hudec-0481495.pdf
Demographic monitoring of Wright fishhook cactus
Ronald J. Kass
2001-01-01
Wright fishhook cactus (Sclerocactus wrightiae Benson) is a small barrel cactus endemic to the San Rafael Swell in south-central Utah. It was listed as an endangered species in 1979 due to its small population size, threats of over-collecting, and development associated with oil and gas. Demographic monitoring was initiated in 1993 with the following objectives: to...
Exact simulation of conditioned Wright-Fisher models.
Zhao, Lei; Lascoux, Martin; Waxman, David
2014-12-21
Forward and backward simulations play an increasing role in population genetics, in particular when inferring the relative importance of evolutionary forces. It is therefore important to develop fast and accurate simulation methods for general population genetics models. Here we present an exact simulation method that generates trajectories of an allele׳s frequency in a finite population, as described by a general Wright-Fisher model. The method generates conditioned trajectories that start from a known frequency at a known time, and which achieve a specific final frequency at a known final time. The simulation method applies irrespective of the smallness of the probability of the transition between the initial and final states, because it is not based on rejection of trajectories. We illustrate the method on several different populations where a Wright-Fisher model (or related) applies, namely (i) a locus with 2 alleles, that is subject to selection and mutation; (ii) a locus with 3 alleles, that is subject to selection; (iii) a locus in a metapopulation consisting of two subpopulations of finite size, that are subject to selection and migration. The simulation method allows the generation of conditioned trajectories that can be used for the purposes of visualisation, the estimation of summary statistics, and the development/testing of new inferential methods. The simulated trajectories provide a very simple approach to estimating quantities that cannot easily be expressed in terms of the transition matrix, and can be applied to finite Markov chains other than the Wright-Fisher model. Copyright © 2014 Elsevier Ltd. All rights reserved.
Borbulevych, Oleg Y; Plumley, Joshua A; Martin, Roger I; Merz, Kenneth M; Westerhoff, Lance M
2014-05-01
Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein-ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.
Renstrom, Arthur G. (Compiler); Goldblatt, Roberta W.; Minkus, Carl; Berube, Karen L.; Launius, Roger (Technical Monitor)
2002-01-01
This annotated bibliography of material about Wilbur and Orville Wright and the first powered flight, commemorates the one hundredth anniversary of the event. This publication represents an updated version of the classic, "Wilbur and Orville Wright: A Bibliography Commemorating the Hundredth Anniversary of the Birth of Wilbur Wright, April 16, 1867" which was originally published in 1968. Aspects of the Wright brothers' lives covered include: their published writings, biographical references, airplanes used and flight records, airplane components, patents, court records, Wright companies and schools, the Wright-Smithsonian controversy, monuments and museums, memorials, medals and honors, memorabilia, art, poetry, music, motion pictures and juvenile publications. An index is included.
Single and simultaneous binary mergers in Wright-Fisher genealogies.
Melfi, Andrew; Viswanath, Divakar
2018-05-01
The Kingman coalescent is a commonly used model in genetics, which is often justified with reference to the Wright-Fisher (WF) model. Current proofs of convergence of WF and other models to the Kingman coalescent assume a constant sample size. However, sample sizes have become quite large in human genetics. Therefore, we develop a convergence theory that allows the sample size to increase with population size. If the haploid population size is N and the sample size is N 1∕3-ϵ , ϵ>0, we prove that Wright-Fisher genealogies involve at most a single binary merger in each generation with probability converging to 1 in the limit of large N. Single binary merger or no merger in each generation of the genealogy implies that the Kingman partition distribution is obtained exactly. If the sample size is N 1∕2-ϵ , Wright-Fisher genealogies may involve simultaneous binary mergers in a single generation but do not involve triple mergers in the large N limit. The asymptotic theory is verified using numerical calculations. Variable population sizes are handled algorithmically. It is found that even distant bottlenecks can increase the probability of triple mergers as well as simultaneous binary mergers in WF genealogies. Copyright © 2018 Elsevier Inc. All rights reserved.
A weak Galerkin least-squares finite element method for div-curl systems
Li, Jichun; Ye, Xiu; Zhang, Shangyou
2018-06-01
In this paper, we introduce a weak Galerkin least-squares method for solving div-curl problem. This finite element method leads to a symmetric positive definite system and has the flexibility to work with general meshes such as hybrid mesh, polytopal mesh and mesh with hanging nodes. Error estimates of the finite element solution are derived. The numerical examples demonstrate the robustness and flexibility of the proposed method.
78 FR 76969 - Wright Brothers Day, 2013
2013-12-19
... champion STEM education in their communities. As we remember the Wright brothers, let us not forget another... results. That is why my Administration is dedicated to improving education in the vital fields of science... underrepresented groups, and through Race to the Top, we are raising standards and making STEM education a priority...
Plegaria, Jefferson S; Dzul, Stephen P; Zuiderweg, Erik R P; Stemmler, Timothy L; Pecoraro, Vincent L
2015-05-12
De novo protein design is a biologically relevant approach that provides a novel process in elucidating protein folding and modeling the metal centers of metalloproteins in a completely unrelated or simplified fold. An integral step in de novo protein design is the establishment of a well-folded scaffold with one conformation, which is a fundamental characteristic of many native proteins. Here, we report the NMR solution structure of apo α3DIV at pH 7.0, a de novo designed three-helix bundle peptide containing a triscysteine motif (Cys18, Cys28, and Cys67) that binds toxic heavy metals. The structure comprises 1067 NOE restraints derived from multinuclear multidimensional NOESY, as well as 138 dihedral angles (ψ, φ, and χ1). The backbone and heavy atoms of the 20 lowest energy structures have a root mean square deviation from the mean structure of 0.79 (0.16) Å and 1.31 (0.15) Å, respectively. When compared to the parent structure α3D, the substitution of Leu residues to Cys enhanced the α-helical content of α3DIV while maintaining the same overall topology and fold. In addition, solution studies on the metalated species illustrated metal-induced stability. An increase in the melting temperatures was observed for Hg(II), Pb(II), or Cd(II) bound α3DIV by 18-24 °C compared to its apo counterpart. Further, the extended X-ray absorption fine structure analysis on Hg(II)-α3DIV produced an average Hg(II)-S bond length at 2.36 Å, indicating a trigonal T-shaped coordination environment. Overall, the structure of apo α3DIV reveals an asymmetric distorted triscysteine metal binding site, which offers a model for native metalloregulatory proteins with thiol-rich ligands that function in regulating toxic heavy metals, such as ArsR, CadC, MerR, and PbrR.
The Wright Brothers and their First Flight
Indian Academy of Sciences (India)
Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 12. The Wright Brothers and their First Flight. O N Ramesh. Article-in-a-Box Volume 8 Issue 12 December 2003 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/008/12/0003-0004 ...
Renormalization analysis of catalytic Wright-Fisher diffusions
Czech Academy of Sciences Publication Activity Database
Swart, Jan M.; Fleischmann, K.
2006-01-01
Roč. 2006, č. 11 (2006), s. 585-654 ISSN 1083-6489 R&D Projects: GA ČR GA201/06/1323 Institutional research plan: CEZ:AV0Z10750506 Keywords : renormalization * catalytic Wright-Fisher diffusion * embedded particle system * extinction * unbounded growth * interacting diffusions * universality Subject RIV: BA - General Mathematics Impact factor: 0.676, year: 2006
The Wright Science Colloquia Entering the Nano-World
2002-01-01
In 1965, Intel co-founder Gordon Moore made an astonishing prediction - that every two years processing power would double. This prediction has always proved accurate. Accordingly, the first Intel processor produced in 1975 was equipped with 2,300 transistors whereas the latest edition has 55 million. Today we have this extraordinary process of miniaturisation to thank for cell phones, computers and other, ever more compact electronic marvels. But where will the miniaturisation race end? What will happen when electronic etchings reach the size of an atom? These questions are on the programme of the 10th Wright Science Colloquia from 18 to 22 November. Five world-renowned specialists will explain to the general public the saga of miniaturisation. The Wright Colloquia take place every two years in Geneva and aim to inform the general public about the latest advances in science. Monday 18 November: 'Shaping the World at the Atomic Scale', by Donald Eigler, IBM, Almaden, USA. Tuesday 19...
Passion play: Will Wright and games for science learning
Ching, Dixie
2012-12-01
Researchers and instructional designers are exploring the possibilities of using video games to support STEM education in the U.S., not only because they are a popular media form among youth, but also because well-designed games often leverage the best features of inquiry learning. Those interested in using games in an educational capacity may benefit from an examination of the work of video game designer Will Wright. Wright designs through a constructivist lens and his open-ended, sandbox games ( SimCity, The Sims, Spore) present wide "possibility spaces" that allow players to exercise their critical thinking and problem solving skills. His games invoke a delight in discovery that inspire creative acts and interest-driven learning both during and outside of the game. Finally, he reminds us that failure-based learning is a viable strategy for building expertise and understanding.
The Holiversity. A Perspective on the Wright Report.
Adelman, Howard
After a decade of almost unlimited funds, the universities in Ontario are faced not only with declining enrollments but with an attack on their very function and role. The Wright Report, the final version of the Report of the Commission on Post-Secondary Education in Ontario, appeared early in 1973. It has engendered major controversy, and its…
Analysis of biological spectrum of Divčibare flora
Directory of Open Access Journals (Sweden)
Popović Ivana
2006-01-01
Full Text Available One of the essential analyses which is performed during the floristic study of a region is the analysis of the biological spectrum. The analysis of the biological spectrum of the flora includes the determination of the type of life form for each taxon described in the flora of the study region. If it is considered that life form is a specific structural-functional response to the environmental effects and the result of the adaptation during the species evolution, it is clear that the basic characteristics of the site are more or less reflected in any life form. This fact is confirmed by the analysis of the biological spectrum of Divčibare flora. The study results are in correlation with the results of the analysis of the biological spectrum of the flora of Serbia and the Balkan Peninsula.
Ishikawa, Kazuki; Matsuoka, Satoshi; Hara, Hiroshi; Matsumoto, Kouji
2017-10-18
The Min system, which inhibits assembly of the cytokinetic protein FtsZ, is largely responsible for positioning the division site in rod-shaped bacteria. It has been reported that MinJ, which bridges DivIVA and MinD, is targeted to the cell poles by an interaction with DivIVA, and that MinJ in turn recruits MinCD to the cell poles. MinC, however, is located primarily at active division sites at mid-cell when expressed from its native promoter. Surprisingly, we found that Bacillus subtilis MinD is located at nascent septal membranes and at an asymmetric site on lateral membranes between nascent septal membranes in filamentous cells lacking MinJ or DivIVA. Bacillus subtilis MinD has two amphipathic α-helices rich in basic amino acid residues at its C-terminus; one of these, named MTS1 here, is the counterpart of the membrane targeting sequence (MTS) in Escherichia coli MinD while the other, named MTS-like sequence (MTSL), is the nearest helix to MTS1. These amphipathic helices were located independently at nascent septal membranes in cells lacking MinJ or DivIVA, whereas elimination of the helices from the wild type protein reduced its localization considerably. MinD variants with altered MTS1 and MTSL, in which basic amino acid residues were replaced with proline or acidic residues, were not located at nascent septal membranes, indicating that the binding to the nascent septal membranes requires basic residues and a helical structure. The septal localization of MTSL, but not of MTS1, was dependent on host cell MinD. These results suggest that MinD is targeted to nascent septal membranes via its C-terminal amphipathic α-helices in B. subtilis cells lacking MinJ or DivIVA. Moreover, the diffuse distribution of MinD lacking both MTSs suggests that only a small fraction of MinD depends on MinJ for its localization to nascent septal membranes.
"Ingraham v. Wright" and the Decline of Due Process.
Clark, Gerard J.
1978-01-01
Suggests that the constitutional questions in "Ingraham vs Wright" lend credence to a concern that the Court is seeking to eliminate all due process intervention outside of the incorporation and privacy cases and to limit even these cases to defenses of a criminal prosecution. Available from Suffolk University Law Review Office, 41…
Filipsone, Anta
2009-01-01
On the basis of a comparison of the educational approaches of Andrew Wright and David Hay this paper illustrates the persisting problem of dichotomising cognitive and trans-cognitive aspects of spiritual development and education. Even though both Wright and Hay speak of the same topic--spirituality and spiritual education--they define these terms…
Wright tariffs in the Spanish electricity industry: the case of residential consumption
International Nuclear Information System (INIS)
Castro-Rodriguez, F.
1999-01-01
In this paper a capacity price model is developed for the Spanish electricity industry which allows the presentation of the Spanish utilization level tariffs as an example of duration tariffs (Wright tariffs) when duration is approximated by the ratio of consumption to power used. Using this model and data on the residential consumption of electricity, several optimal two-part tariffs are computed, considering different hypothesis on the configuration of the generating equipment. It has been found that the optimal tariff maintaining universal service increases welfare if the generating equipment and the output assignment to the different technologies are taken as given. Furthermore, if the regulator is concerned not only with efficiency, but also with distributive issues, then welfare losses associated with the existing regulatory regime are even larger
Directory of Open Access Journals (Sweden)
Yassaei S
2007-01-01
Full Text Available Background and Aim: Unlike other bones of the head and neck, hyoid bone has no bony articulations. It is connected to mandible, cranium and pharynx through muscles and ligaments. During treatment with functional appliance in patients with class II div1 malocclusion, mandible is positioned in inferior and anterior direction. Regarding the relation between hyoid and mandibular bone, alterations of hyoid bone position can be a result of functional appliance therapy. The aim of this study was to evaluate the changes of hyoid bone position following treatment with Farmand functional appliance in patients with class II div 1 malocclusion. Materials and Methods: In this before-after clinical trial, 28 patients with class II div 1 malocclusion which were under treatment with Farmand functional appliance for 11 months were selected. Facial growth in vertical, normal or horizontal direction was determined by cephalometric measurement. Data were analyzed with Paired-t test to compare the differences of mean values pre and post treatment. Variance analysis was used to compare the three growth patterns. P<0.05 was considered as the limit of significance. Results: Hyoid bone shifted significantly forward in horizontal dimension (P<0.01 and non-significantly upward in vertical dimension. There was no significant difference among the three studied groups with respect to hyoid bone position alterations in horizontal dimension but significant difference was observed between horizontal and vertical growth pattern in vertical dimension (P<0.05. There was significant correlation between decrease of ANB angle and forward movement of hyoid bone. Conclusion: Based on the results of this study, treatment with Farmand functional appliance (Fa II leads to significant alterations in the position and anterior displacement of the hyoid bone.
Divórcio e funcionamento psicológico em adultos e crianças
Silva, Diogo Jorge Pereira do Vale Lamela da
2013-01-01
Tese de doutoramento em Psicologia (área de especialização de Psicologia Clínica) A presente dissertação foi orientada por dois enquadramentos teóricos: o modelo de Desenvolvimento Positivo da Personalidade na idade adulta (Staudinger & Bowen, 2010) e no modelo ecológico da coparentalidade (Feinberg, 2003). Objetivo: Este trabalho pretendeu responder a quatro objetivos. (1) Identificar variáveis sócio-demográficas, características do divórcio e indicadores personológicos qu...
Heister, Timo
2012-01-29
Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.
Heister, Timo; Rapin, Gerd
2012-01-01
Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.
Wright-Patterson Air Force Base: The First Century
2015-01-01
aside in 1934 to house a Transient Camp for temporary workers employed under Depression -era programs. During 1934 and 1935, these men labored on...The 445th Airlift Wing upgraded from C-141s to C-5As between 2005 and 2007, before transitioning to C-17s in 2012. The Centennial of Flight was a...December 2002 on Wright Brothers Hill. The event initiated the nation’s commemoration of the Centennial of Flight. These actions symbolized the
Richard Wright, Toni Morrison, and United States book clubs
Directory of Open Access Journals (Sweden)
Mark Madigan
2004-12-01
Full Text Available This essay focuses on the influence of commercial book clubs in the United States. It will examine the country's oldest commercial book club, the Book-of-the-Month Club (BOMC, Oprah's Book Club (OBC, which bears the name of its founder, television personality Oprah Winfrey, and their roles in the careers of two African-American authors, Richard Wright and Toni Morrison.
Graves, M; Schermer, V L
1998-12-01
James Wright's work is multilayered. Taken as a whole, which Annie Wright's beautiful compilation, Above the River, allows one to do, Wright's poems (as well as his masterful "prose poems") have a pattern akin to a mythic cycle. "Mythemes" (Lévi-Strauss, 1979) recur as dialectic opposites from one poem to another, whether the abandoned male and mysterious woman, humankind and nature, blindness and seeing, secrets and revelation. Suggestive and symbolic forms such as birds, horses, earth, sky, the destitute, rivers, and adolescence weave themselves throughout in inner and outer "landscapes" of images and experiential moments. There is a frequent shift of "gestalts" between the inner world and external reality. Such a "blooming, buzzing confusion" of internal and external referents might appear to be psychotic and imply a loss of "reality testing." Chassaguet-Smirgel (1988), citing Oscar Wilde's The Picture of Dorian Gray as an example, contended that the artist narrowly averts psychosis by transforming it into a work of art. Surrealists, for whom the psychoanalyst Jacques Lacan was an important figure (cf. Sarup, 1992, pp. 17-27), elevated psychosis to the status of art, and Wright has been considered to be a surrealistic poet, although he himself denied such an affiliation. Hall (Wright, 1990, Introduction, pp. xxiii-xxxvii) suggests that Wright, in addition to an extensive history of alcoholism, from which he seemed to recover towards the end of his life, suffered from a major mental illness, which included episodes of severe depression, hospitalizations, and at least one suicide attempt. The severity of the asceticism and the extreme damage to the self in some Wright's work suggests their roots in early traumatic experiences. (A terribly damaged yet heroic personage, whose disfigurement perhaps symbolizes the poet's trauma, is "Hook" [ATR, pp. 315-316], about a man who gives his last few cents to the poet with a hook replacing his amputated hand.) Not enough is
The dangers of eating away from home: review | Wright | South ...
African Journals Online (AJOL)
The dangers of eating away from home: review. JP Wright. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...
He, Zhangyi; Beaumont, Mark; Yu, Feng
2017-07-05
We explore the effect of different mechanisms of natural selection on the evolution of populations for one- and two-locus systems. We compare the effect of viability and fecundity selection in the context of the Wright-Fisher model with selection under the assumption of multiplicative fitness. We show that these two modes of natural selection correspond to different orderings of the processes of population regulation and natural selection in the Wright-Fisher model. We find that under the Wright-Fisher model these two different orderings can affect the distribution of trajectories of haplotype frequencies evolving with genetic recombination. However, the difference in the distribution of trajectories is only appreciable when the population is in significant linkage disequilibrium. We find that as linkage disequilibrium decays the trajectories for the two different models rapidly become indistinguishable. We discuss the significance of these findings in terms of biological examples of viability and fecundity selection, and speculate that the effect may be significant when factors such as gene migration maintain a degree of linkage disequilibrium. Copyright © 2017 He et al.
Storm, R.; Benson, T.; Galica, C.; McCredie, P.
2003-01-01
This guide was produced by the NASA Glenn Research Center Office of Educational Programs in Cleveland, OH, and the NASA Aerospace Educational Coordinating Committee. It includes activity modules for students, including the history of the Wright Brothers and their family in Dayton, Ohio and flight experimentation in Kitty Hawk, North Carolina. Student activities such as building models of the Wright Brothers glider and writing press releases of the initial flight are included.
Rosales, Alirio
2017-04-01
Theories are composed of multiple interacting components. I argue that some theories have narratives as essential components, and that narratives function as integrative devices of the mathematical components of theories. Narratives represent complex processes unfolding in time as a sequence of stages, and hold the mathematical elements together as pieces in the investigation of a given process. I present two case studies from population genetics: R. A. Fisher's "mas selection" theory, and Sewall Wright's shifting balance theory. I apply my analysis to an early episode of the "R. A. Fisher - Sewall Wright controversy." Copyright © 2017 Elsevier Ltd. All rights reserved.
Statistical Basis for Predicting Technological Progress
Nagy, Béla; Farmer, J. Doyne; Bui, Quan M.; Trancik, Jessika E.
2013-01-01
Forecasting technological progress is of great interest to engineers, policy makers, and private investors. Several models have been proposed for predicting technological improvement, but how well do these models perform? An early hypothesis made by Theodore Wright in 1936 is that cost decreases as a power law of cumulative production. An alternative hypothesis is Moore's law, which can be generalized to say that technologies improve exponentially with time. Other alternatives were proposed by Goddard, Sinclair et al., and Nordhaus. These hypotheses have not previously been rigorously tested. Using a new database on the cost and production of 62 different technologies, which is the most expansive of its kind, we test the ability of six different postulated laws to predict future costs. Our approach involves hindcasting and developing a statistical model to rank the performance of the postulated laws. Wright's law produces the best forecasts, but Moore's law is not far behind. We discover a previously unobserved regularity that production tends to increase exponentially. A combination of an exponential decrease in cost and an exponential increase in production would make Moore's law and Wright's law indistinguishable, as originally pointed out by Sahal. We show for the first time that these regularities are observed in data to such a degree that the performance of these two laws is nearly the same. Our results show that technological progress is forecastable, with the square root of the logarithmic error growing linearly with the forecasting horizon at a typical rate of 2.5% per year. These results have implications for theories of technological change, and assessments of candidate technologies and policies for climate change mitigation. PMID:23468837
Statistical basis for predicting technological progress.
Directory of Open Access Journals (Sweden)
Béla Nagy
Full Text Available Forecasting technological progress is of great interest to engineers, policy makers, and private investors. Several models have been proposed for predicting technological improvement, but how well do these models perform? An early hypothesis made by Theodore Wright in 1936 is that cost decreases as a power law of cumulative production. An alternative hypothesis is Moore's law, which can be generalized to say that technologies improve exponentially with time. Other alternatives were proposed by Goddard, Sinclair et al., and Nordhaus. These hypotheses have not previously been rigorously tested. Using a new database on the cost and production of 62 different technologies, which is the most expansive of its kind, we test the ability of six different postulated laws to predict future costs. Our approach involves hindcasting and developing a statistical model to rank the performance of the postulated laws. Wright's law produces the best forecasts, but Moore's law is not far behind. We discover a previously unobserved regularity that production tends to increase exponentially. A combination of an exponential decrease in cost and an exponential increase in production would make Moore's law and Wright's law indistinguishable, as originally pointed out by Sahal. We show for the first time that these regularities are observed in data to such a degree that the performance of these two laws is nearly the same. Our results show that technological progress is forecastable, with the square root of the logarithmic error growing linearly with the forecasting horizon at a typical rate of 2.5% per year. These results have implications for theories of technological change, and assessments of candidate technologies and policies for climate change mitigation.
Wright Science Colloquium 2004
2004-01-01
"Stem cells and regenerative medicine. Living a longer life?" For the first time in history, human beings are in a position to modify their own biological fate. This is due to the past 20 years of basic research in life sciences, which have led to discoveries of great impact, not only on our scientific knowledge, but also on a variety of domains outside science itself. Our society is disconcerted by this biological revolution and the underlying instrumentalisation of human beings. Therefore, it is the right time to think about these extraordinary developments, to know where we stand and to try to imagine the future, in order to foresee both the benefits and the dangers of what will unavoidably occur. From 15 to 19 November, the XIth edition of the Colloquia Wright that are held every two years in Geneva with the aim of presenting the latest scientific findings to the general public, will deal with this new and difficult question for the society. Five world-famous scientists will present lectures every da...
Wright Science Colloquium 2004
2004-01-01
"Stem cells and regenerative medicine. Living a longer life?" For the first time in history, human beings are in a position to modify their own biological fate. This is due to the past 20 years of basic research in life sciences, which have led to discoveries of great impact, not only on our scientific knowledge, but also on a variety of domains outside science itself. Our society is disconcerted by this biological revolution and the underlying instrumentalisation of human beings. Therefore, it is the right time to think about these extraordinary developments, to know where we stand and to try to imagine the future, in order to foresee both the benefits and the dangers of what will unavoidably occur. From 15 to 19 November, the XIth edition of the Colloquia Wright that are held every two years in Geneva with the aim of presenting the latest scientific findings to the general public, will deal with this new and difficult question for the society. Five world-famous scientists will present lectures every...
Digital Documentation of Frank Lloyd Wright's Masterpiece, Fallingwater
Jerome, P.; Emilio, D.
2017-08-01
Since 1988, the professional staff of Architectural Preservation Studio (APS) has been involved with the conservation of Frank Lloyd Wright's Fallingwater in Mill Run, PA. Designed and erected from 1935 to 1939 as a weekend home for the Kauffman family, the complex consists of the main house and guest house. After five years of reports and prototype repairs, we produced a two-volume master plan. Using original Frank Lloyd Wright drawings from Avery Library as background drawings, we measured every surface and reproduced the drawings in CAD, also developing elevations of every room. Stone-by-stone drawings of every flagstone floor and terrace scheduled to be lifted were also created using overlapping film photography that was assembled into a photo mosaic. By 2005, we designed, administered and completed a four-phase exterior restoration, with the paint-stripping and repainting of interior rooms being performed during the brief winter period when the building is closed to the public on an ongoing basis. In 2016, we were invited back to the site to review conditions and advise on routine maintenance. At that time we proposed to re-document the buildings, this time using laser-scanning. Laser-scanning of the exterior was performed in May of 2016, and of the interior in March 2017, each over the course of four days. This paper will make a comparison between manual and digital techniques in terms of Fallingwater's documentation.
(Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio)
Energy Technology Data Exchange (ETDEWEB)
1991-10-01
This report presents information concerning field procedures employed during the monitoring, well construction, well purging, sampling, and well logging at the Wright-Patterson Air Force Base. Activities were conducted in an effort to evaluate ground water contamination.
Sewall Wright's equation Deltaq=(q(1-q) partial differentialw/ partial differentialq)/2w.
Edwards, A W
2000-02-01
An equation of Sewall Wright's expresses the change in the frequency of an allele under selection at a multiallelic locus as a function of the gradient of the mean fitness "surface" in the direction in which the relative proportions of the other alleles do not change. An attempt to derive this equation using conventional vector calculus shows that this description leads to a different equation and that the purported gradient in Wright's equation is not a gradient of the mean fitness surface except in the diallelic case, where the two equations are the same. It is further shown that if Fisher's angular transformation is applied to the diallelic case the genic variance is exactly equal to one-eighth of the square of the gradient of the mean fitness with respect to the transformed gene frequency. Copyright 2000 Academic Press.
Ecopoetic Encounters: Amnesia and Nostalgia in Alexis Wright's Environmental Fiction
Barras Arnaud
2015-01-01
In Carpentaria (2006) and The Swan Book (2013), Alexis Wright establishes an allegorical mode where she reimagines Europeans' first encounters with Australia from an Aboriginal environmental perspective. In this narrative system, the discovery of Australia is not realised by exploring colonisers, but by vulnerable strangers who apprehend the continent both experientially and linguistically. In Carpentaria, the Stranger-figure of Elias Smith is left amnesic after surviving a shipwreck during a...
The portrait of a prophet – why is Wright not right about Jesus?
African Journals Online (AJOL)
p1243322
suited to describe the portrait of Jesus emanating from the sources at hand. He furthermore .... Wright maintains that Jesus retold Israel's story, both explicitly and implicitly, as ..... of which were engraved in the palms of their hands. To reduce ...
Directory of Open Access Journals (Sweden)
Alfonso Diaz Segura, Ricardo Meri de la Maza, Bartolomé Serra Soriano
2013-05-01
Full Text Available RESUMEN La estructura de la modernidad, en general, está al servicio de una nueva concepción espacial fluida y continua, condensada en torno al concepto de “planta libre”. Sin embargo, la riqueza y complejidad de articulación que adquieren las plantas, no se observa en la sección de los edificios, especialmente si se trata de rascacielos. El principio de crecimiento por superposición de plantas iguales y el carácter utilitario de la estructura en esta tipología, anularon su carácter iconográfico y su integración espacial. Frank Lloyd Wright, de modo natural, desarrolla una estructura para sus escasos rascacielos que integra espacio y forma, superando así tanto la simplificación funcional de la Escuela de Chicago, como el valor iconográfico de las experiencias europeas.SUMMARY In general, the structure of modernity serves a new, fluid and continuous, spatial conception, condensed around the “free floor” concept. However, the wealth and complexity of articulation that these floors acquire are not seen in the section of the buildings, especially in the case of skyscrapers. The principle of growth by superimposition of equal floors and the utilitarian character of the structure in this type of building, nullify the iconographic character of the structure and its spatial integration. Frank Lloyd Wright develops a structure for his few skyscrapers that integrates space and form in a natural way, thus surpassing both the functional simplification of the Chicago School, and the iconographic value of the European experiences.
Invertendo a “Passagem Atlântica”: O “regresso” de Richard Wright a África
Directory of Open Access Journals (Sweden)
Ana Luísa Saraiva
2012-10-01
Full Text Available O texto discute o sentido polémico do “regresso” a África que Richard Wright inscreve em Black Power e a forma como a narrativa da viagem subverte a “Middle Passage”. O sujeito narrativo orienta o leitor através de uma incursão pessoal nos muitos sentidos da modernidade e desdobra a noção de “destino comum”, já apontada em 12 Million Black Voices. Contudo, qualquer sentido de comunidade é aqui necessariamente ambíguo, por estar sempre relacionado com questões de raça e identidade. Black Power é uma narrativa importante para o conceito de modernidade e assinala uma mudança significativa na produção literária de Wright para uma vertente não-ficcional. Esta segunda fase da sua obra contém, no entanto, um paradoxo crucial: enquanto se volta para o exterior, para o mundo mais global, Wright tenta, simultaneamente, inscrever-se como referência sobre o locus do qual nunca poderia demarcar‑se: África. Em Black Power, a duboisiana “color line” desdobra‑se em múltiplas dimensões.
Space power technology for the twenty-first century (SPT21)
International Nuclear Information System (INIS)
Borger, W.U.; Massie, L.D.
1988-01-01
During the spring and summer months of 1987, the Aero Propulsion Laboratory of the Air Force Wright Aeronautical Laboratories, Wright-Patterson AFB, Ohio in cooperation with the Air Force Space Technology Center at Kirtland AFB, New Mexico, undertook an initiative to develop a Strategic Plan for Space Power Technology Development. The initiative was called SPT21, Space Power Technology for the Twenty-First Century. The planning process involved the participation of other Government organizations (U.S. Army, Navy, DOE and NASA) along with major aerospace companies and universities. Following an SPT21 kickoff meeting on 28 May 1987, detailed strategic planning was accomplished through seven (7) Space Power Technology Discipline Workshops commencing in June 1987 and concluding in August 1987. Technology Discipline Workshops were conducted in the following areas: (1) Solar Thermal Dynamic Power Systems (2) Solar Photovoltaic Cells and Arrays (3) Thermal Management Technology (4) Energy Storage Technology (5) Nuclear Power Systems Technology (6) Power Conditioning, Distribution and Control and (7) Systems Technology/Advanced Concepts. This technical paper summarizes the planning process and describes the salient findings and conclusions of the workshops
76 FR 1211 - Union Pacific Railroad Company-Abandonment Exemption-In Wright County, IA
2011-01-07
... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. AB 33 (Sub-No. 293X)] Union Pacific Railroad Company--Abandonment Exemption--In Wright County, IA Union Pacific Railroad Company (UP) filed a verified notice of exemption under 49 CFR 1152 subpart F--Exempt Abandonments to abandon a line...
International Nuclear Information System (INIS)
Rothenberg, Alexis B.; Berdon, Walter E.; D'Angio, Giulio J.; Yamashiro, Darrell J.; Cowles, Robert A.
2009-01-01
Neuroblastoma is often widespread at the time of diagnosis. Three physicians between 1900 and 1910 played an important role in the pathologic definition of neuroblastoma and its route of spread in relation to the age of the patient. These findings eventually led to the advances in treatment and decreased morbidity of today. In 1910 James Homer Wright was the first to recognize the tumor as being of primitive neural cell origin, calling it neuroblastoma and emphasizing the bundle of cells termed rosettes. While Wright recognized the neural nature of the tumor, the authors of previous reports had described its two distinct patterns of spread. In 1901 William Pepper published a series of infants with massive hepatic infiltration associated with adrenal tumors without spread to bone, and in 1907 Robert Grieve Hutchison reported his experience with a similar pathologic process in older infants and children who had orbital and skull metastases. Wright's valuable unifying concept served to tie together the descriptions of Pepper and Hutchison. A century later the names of these physicians should be remembered - Wright, who defined the adrenal tumor as of primitive neural origin, Pepper for his clinically accurate report of massive liver involvement in the infant, and Hutchison for describing the propensity of the tumor to spread to bone in older children. (orig.)
Institute of Scientific and Technical Information of China (English)
肖志宏
2017-01-01
How the southern black migrants navigate and survive the northern urban space is a question profoundly explored and realistically documented in many migration narratives in African American literature. This paper concentrates on the image of Chicago"kitchenette"in the works of Richard Wright and Gwendolyn Brooks, in an attempt to demonstrate the different inter-pretations of migrant spaces on the urban landscape.
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B. Serra Soriano
2017-06-01
Full Text Available Within his large architectural production, Frank Lloyd Wright had the opportunity to experiment with the timber industrialization, linking a traditional material with the modern sense of architecture. Wood and Frank Lloyd Wright are inseparable from the balloon frame system, a system which he will use at his first housing and through which he will materialize the spatial decomposition concept. The research on the particular American System-Built Houses case will serve to show the earliest experiences of Wright with the industry, whose conclusions he would use for subsequent researches on prefabrication.
SiDIVS: Simple Detection of Inductive Vehicle Signatures with a Multiplex Resonant Sensor
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José J. Lamas-Seco
2016-08-01
Full Text Available This work provides a system capable of obtaining simultaneous inductive signatures of vehicles traveling on a roadway with minimal cost. Based on Time-Division Multiplexing (TDM with multiple oscillators, one for each inductive loop, the proposed system detects the presence of vehicles by means of a shift in the oscillation period of the selected loop and registers the signature of the detected vehicles by measuring the duration of a fixed number of oscillator pulses. In order to test the system in an actual environment, we implement a prototype that we denote as SiDIVS (Simple Detection of Inductive Vehicle Signatures and acquire different vehicle inductive signatures under real scenarios. We also test the robustness of the detector by simulating the effect of noise on the signature acquisition.
3 CFR 8466 - Proclamation 8466 of December 16, 2009. Wright Brothers Day, 2009
2010-01-01
... alter our world. Today, we honor the enduring American spirit of creativity and innovation that made the.... In these challenging times, the story of Orville and Wilbur Wright reminds us of what can be accomplished when imagination is joined with tenacity. Their spirit lives on in every garage and basement...
The portrait of a prophet – why is Wright not right about Jesus ...
African Journals Online (AJOL)
question and then bases a reconstruction of Jesus on this answer. What, then, are his sources and how does he apply them to arrive at these conclusions? This article presents the portrait Wright painted of the historical Jesus and investigates how it was arrived at. HTS Theological Studies/Teologiese Studies Vol.
"Wrighting" the Self: New Technologies and Textual Subjectivities
Sakr, Mona
2012-01-01
The expression of the self through multimodal texts is a central theme in education. While it has been suggested that new technologies act as important mediators in the relationship between texts and subjectivity, the mechanisms underlying such mediation has been a neglected topic of research. This paper considers the theoretical assumptions upon…
El Hotel Imperial de Tokyo de Frank Lloyd Wright. Un monumento del siglo XX redivivo
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Fernando Vegas López-Manzanares
2004-12-01
Full Text Available El texto describe el arco temporal que discurre desde el nacimiento del hotel hasta el momento de su reconstrucción. En primer lugar, indaga en la genealogía del proyecto, para abundar posteriormente en los entresijos de su construcción. Su supuesta condición indemne tras el terremoto de Kanto dio alas a Wright para reivindicar su genialidad y permitió su mitificación, aunque este hecho no sirviera para evitar las bombas en la segunda guerra mundial, ni su demolición posterior. Al hilo del discurso, se realiza una incursión en el mundo de las patologías que afectan a las obras de Wright, en la destrucción de algunas de ellas y en la relación personal del arquitecto con el mundo de la restauración.
Analysis of the bioclimatic strategies used by Frank Lloyd Wright in the Jacobs I house
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M. Beltrán-Fernández
2017-10-01
Full Text Available Frank Lloyd Wright is considered one of the most influential architects of modern architecture due to the spatial and aesthetic qualities of his work. However, the importance of Wright’s construction and environmental solutions has been usually overlooked. In order to evaluate these qualities, the first house that Wright designed for the Jacobs family (Wisconsin, USA, 1937 has been analyzed. This well-known building has been much studied, and its architectural value much celebrated, but without analysing the advantages of the bioclimatic principles over interior environment. But how can the influence of this bioclimatic architecture be measured in terms of thermal comfort? Does the selected orientation improve interior comfort? And what about the natural ventilation or the deep overhangs? In order to assess this, a digital model for energy simulation has been built using Revit and Design Builder.
Felgar, Robert
In "Black Boy," Richard Wright triumphs over an ugly, racist world by fashioning an inspiring, powerful, beautiful, and fictionalized autobiography. To help students understand and appreciate his story in the cultural, political, racial, social, and literary contexts of its time, this casebook provides primary historical documents,…
Maritime Improvised Explosive Devices: A Threat Based Technology Study
2015-06-12
id/3078682/ns/technology_and_science- science/t/dolphins-go-front-lines-iraq-war/#.VPsmDZU5DIV. Carnegie , Dale , and Rita Kiley. 1948. How to Stop...Besides, if I let those things get me, I wouldn’t last long. ( Carnegie and Kiley 1948, 6) ― Admiral Ernest J. King Admiral King’s focus on
Birke, L
2000-01-01
In this article, the author examines the overlap between feminism and animal causes, particularly through the lives of two women, the sculptor, Alice Morgan Wright (1881-1975), and her friend, Edith Goode (1882-1970). Feminism and animal causes had connections in the late nineteenth century, particularly in campaigns to abolish vivisection. Wright and Goode held to these politics throughout their lives, and were "precursors of a generation yet to come" who would argue the connections - as many ecofeminists do today. Both women were involved in suffrage campaigns, and continued to be involved in women's organisations such as the National Woman's Party. They were, however, opposed to all injustice, including human mistreatment of animals. Feminism was, to Wright and Goode, part of a wider set of problems; animal cruelty reflected a greater barbarism leading to mistreatment of humans. Accordingly, they actively campaigned for legislation to protect animals and the environment, and lobbied the fledgling United Nations to include such measures. That challenge to the United Nations represented a unique attempt to bring animals into citizenship' a move being made again today, through initiatives such as the Great Ape Project.
Decentralizing constrained-efficient allocations in the Lagos–Wright pure currency economy
Bajaj, Ayushi; Hu, Tai Wei; Rocheteau, Guillaume; Silva, Mario Rafael
2017-01-01
This paper offers two ways to decentralize the constrained-efficient allocation of the Lagos–Wright (2005) pure currency economy. The first way has divisible money, take-it-or-leave-it offers by buyers, and a transfer scheme financed by money creation. If agents are sufficiently patient, the first best is achieved for finite money growth rates. If agents are impatient, the equilibrium allocation approaches the constrained-efficient allocation asymptotically as the money growth rate tends to i...
Animais, divórcio e consequências jurídicas
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Camilo Henrique Silva
2015-07-01
Full Text Available http://dx.doi.org/10.5007/1807-1384.2015v12n1p102 O presente trabalho, por meio da pesquisa bibliográfica às leis, às decisões judiciais e à doutrina, tem por escopo trazer ao leitor, de maneira objetiva, as reflexões e o posicionamento do ordenamento jurídico brasileiro sobre o tema dos animais de estimação envolvidos em disputas de guarda no processo de divórcio. Nesse contexto, o escrito aborda a lei brasileira sobre guarda, direito de visita e alimentos, e sua utilização, por analogia, aos casos envolvendo animais de estimação, em razão da falta de norma específica. O texto retrata a tarefa dos magistrados e tribunais de se posicionarem nos casos levados a juízo e apresenta requisitos a serem observados para a decisão da lide, com vistas ao bem-estar e interesse do animal. Na disputa judicial pelos animais de estimação é legal a concessão da guarda e direito de visita aos cônjuges-tutores e a imposição de prestar alimentos ao animal.
Hodge, Jonathan
2011-03-01
Historians of science have long been agreeing: what many textbooks of evolutionary biology say, about the histories of Darwinism and the New Synthesis, is just too simple to do justice to the complexities revealed to critical scholarship and historiography. There is no current consensus, however, on what grand narratives should replace those textbook histories. The present paper does not offer to contribute directly to any grand, consensual, narrational goals; but it does seek to do so indirectly by showing how, in just one individual case, details of intellectual biography connect with big picture issues. To this end, I examine here how very diverse scientific and metaphysical commitments were integrated in Sewall Wright's own personal synthesis of biology and philosophy. Taking as the decisive text the short final section of Wright's long 1931 paper on 'Evolution in Mendelian populations,' I examine how his shifting balance theory (SBT) related to his optimum breeding strategy research, his physiological genetics, his general theory of homogenising and heterogenesing causation and his panpsychist view of mind and matter; and I discuss how understanding these relations can clarify Wright's place in the longue durée of evolutionary thought. Copyright © 2010 Elsevier Ltd. All rights reserved.
Energy Technology Data Exchange (ETDEWEB)
Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)
2016-10-15
These affect the mechanical design of the fuel assembly components. And thus, appropriate structural design criteria should also be chosen to incorporate the specific design conditions of the SFR fuel assemblies. Among them, the temperature is one of the most crucial conditions to be concerned because the sodium coolant temperature is normally more than 500ºC which is much higher than that of the LWR (< 350ºC). This implies that a thermal creep should be significantly considered in the SFR fuel assembly mechanical design. In addition to the high temperature condition, an irradiation swelling is also an important behavior that the SFR fuel assembly material should accommodate. To incorporate the temperature and irradiation impacts, the material of the fuel assembly components is presently determined to be made of HT-9, the ferriticmartensitic steel. In this paper, the ASME Sec. III Div. 5 (referred to as ‘Div. 5’ hereinafter), which was developed for a ‘high temperature reactor’, is considered as one of the structural design criteria for the mechanical design of SFR fuel assemblies. In this paper, the stress intensity limits, S{sub m} and S{sub t} of HT-9 were built for the structural criteria of an SFR fuel assembly. S{sub m} is obtained from the ultimate strength. As for S{sub t}, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of S{sub mt}, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as S{sub mt} under the temperature about 470ºC which is relatively low temperature range and over 470ºC with relatively short time duration as 1000 hours. And the S{sub t} is adopted as Smt at over 470ºC and long time duration over 34800 hours, and over 520ºC and 10{sup 4} hours too. And at over 570ºC and 1000 hours, and at over 630ºC and 100 hours, S{sub t} is also adopted for S{sub mt}.
Moore, Kirrily; Alderslade, Philip; Miller, Karen
2016-02-05
A complete taxonomic revision of the genus Primnoisis (Isididae) is presented herein, based on original type material of all nominal species and additional specimens from deep-water surveys in sub-temperate and Antarctic waters. A multi-disciplinary approach was used combining morphological characteristics such as colonial branching patterns, polyp structure, sclerite form and arrangement, together with phylogenetic reconstructions using two mitochondrial gene regions (mtMutS and igr1-cox1). The genus Primnoisis is retained with 7 of the 8 nominal species validated (P. antarctica Wright & Studer, 1889, P. rigida Wright & Studer, 1889, P. ambigua Wright & Studer, 1889, P. delicatula Hickson, 1907, P. fragilis Kükenthal, 1912, P. formosa Gravier, 1913 and P. mimas Bayer & Stefani, 1987), with the eighth (P. sparsa Wright & Studer, 1889), synonymised with P. antarctica. In addition, the species Mopsea gracilis Gravier, 1913 is reassigned to Primnoisis and an additional five new species are described (P. chatham n. sp., P. erymna n. sp., P. millerae n. sp., P. niwa n. sp. and P. tasmani n. sp). Most of the species fell into two clear groups, defined both by morphology and genetic grouping, for which two new sub-genera are proposed (P. (Primnoisis) n. subg. and P. (Delicatisis) n. subg.). Three species, P. ambigua, P. mimas and P. tasmani, could not be placed reliably in either sub-genus due to distinctive morphological features or genetic dissimilarity. It was not possible to confirm the monophyly of the genus due to unresolved relationships with the closely related genus Notisis Gravier, 1913 and an undescribed genus of Mopseinae.
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Bussotti F
2012-12-01
Full Text Available The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe. FunDivEUROPE is a new project aiming at a deeper understanding of the role of forest diversity on ecosystem functions and service provisioning for society. This project combines three scientific platforms: experimental, exploratory and inventory. The exploratory platform is based on the observation of a broad range of properties, traits and ecological processes on a network of ca. 240 natural forest sites representing a gradient of tree species diversity in six focal regions of Europe (Spain, Italy, Germany, Poland, Finland and Romania. The Italian sites are located on the hills of central and Southern Tuscany and represent the category “thermophilous deciduous forest”. Almost one year of fieldwork was needed to select and characterize 36 plots measuring 30 x 30 m. Selection was based on criteria concerning tree mixtures and richness, structural parameters and main environmental variables. The main features of these sites are synthetically presented in this paper together with a short description of the project structure and scope. The aim is also to enhance dissemination of the potential implications for a sustainable forest management in Italy.
Dos modos de situarse en el lugar : Monticello de Thomas Jefferson y Taliesin de F. Lloyd Wright
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Juan Antonio Cortés
2012-12-01
Full Text Available
Resumen
El artículo consiste en una descripción comparada de dos edificios: Monticello ‐la casa que Thomas Jefferson construyó para sí mismo en Virginia‐ y Taliesin ‐la casa y estudio de Frank Lloyd Wright en Wisconsin‐. El texto estudia en primer lugar las fuentes arquitectónicas y la evolución del proyecto de Monticello, para centrarse después en la explicación de Taliesin. Hay una cierta similitud en el modo en que Monticello y las casas de Wright ‐en concreto la Ward Willitts‐ se extienden horizontalmente en el terreno y, volviendo a Taliesin, la tesis principal del texto es que tanto la residencia de Jefferson como la de Wright se asientan sobre una colina, pero Monticello ‘corona’ su cima, mientras que Taliesin la bordea, se sitúa como una ‘ceja’ respecto a la misma. En definitiva, de este último edificio se puede afirmar que es una ‘casa natural’, que logra una plena integración entre arquitectura y naturaleza.
Palabras clave
casa, proyecto, evolución, corona, natural
Abstract
This article consists of a comparative description of two buildings: Monticello, Thomas Jefferson’s residence which he built for himself in Virginia, and Taliesin, the studio and home of Frank Lloyd Wright in Wisconsin. First, the text studies the architectural references and evolution of the project for Monticello, in order to later focus on explaining Taliesin. There is a certain similarity in the way that Monticello and Wright’s houses (especially the Ward Willits House extend horizontally across the land. The thesis of this article is that both Jefferson’s and Wright’s residences rest upon a hill, but Monticello crowns the top while Taliesin borders it like an eyebrow. In conclusion, we can say that Taliesin is a “natural house”, which manages to fully integrate its architecture with nature
Collaboration, Reputation, and Ethics in American Academic Life: Hans H. Gerth and C. Wright Mills.
Oakes, Guy; Vidich, Arthur J.
Using the collaboration between sociologist C. Wright Mills and Hans H. Gerth and their studies of the work of Max Weber as a point of departure for a sustained discussion of academic ethics, this book explores how concealment, secrecy, and deception contribute to the building of academic reputation and how the balance of knowledge and power in a…
Brewton, Butler E.
Richard Wright's literary work emphasizes a contrast between black women and white women. Although both are "givers" to black boys, the nature of what they give is different. The black woman gives physical life, feeds it, and protects it at the expense of spiritual or creative vitality. Her goal is to survive bodily, to breathe, to have…
The Impact of Grading on a Curve: Assessing the Results of Kulick and Wright's Simulation Analysis
Bailey, Gary L.; Steed, Ronald C.
2012-01-01
Kulick and Wright concluded, based on theoretical mathematical simulations of hypothetical student exam scores, that assigning exam grades to students based on the relative position of their exam performance scores within a normal curve may be unfair, given the role that randomness plays in any given student's performance on any given exam.…
Dumouchelle, D.H.; Schalk, C.W.; Rowe, G.L.; De Roche, J.T.
1993-01-01
Ground water is the primary source of water in the Wright-Patterson Air Force Base area. The aquifer consists of glacial sands and gravels that fill a buried bedrock-valley system. Consolidated rocks in the area consist of poorly permeable Ordovician shale of the Richmondian stage, in the upland areas, the Brassfield Limestone of Silurian age. The valleys are filled with glacial sediments of Wisconsinan age consisting of clay-rich tills and coarse-grained outwash deposits. Estimates of hydraulic conductivity of the shales based on results of displacement/recovery tests range from 0.0016 to 12 feet per day; estimates for the glacial sediments range from less than 1 foot per day to more than 1,000 feet per day. Ground water flow from the uplands towards the valleys and the major rivers in the region, the Great Miami and the Mad Rivers. Hydraulic-head data indicate that ground water flows between the bedrock and unconsolidated deposits. Data from a gain/loss study of the Mad River System and hydrographs from nearby wells reveal that the reach of the river next to Wright-Patterson Air Force Base is a ground-water discharge area. A steady-state, three-dimensional ground-water-flow model was developed to simulate ground-water flow in the region. The model contains three layers and encompasses about 100 square miles centered on Wright-Patterson Air Force Base. Ground water enters the modeled area primarily by river leakage and underflow at the model boundary. Ground water exits the modeled area primarily by flow through the valleys at the model boundaries and through production wells. A model sensitivity analysis involving systematic changes in values of hydrologic parameters in the model indicates that the model is most sensitive to decreases in riverbed conductance and vertical conductance between the upper two layers. The analysis also indicates that the contribution of water to the buried-valley aquifer from the bedrock that forms the valley walls is about 2 to 4
The Wright Science Colloquia - Entering the Nano-World
2002-01-01
In 1965, Intel co-founder Gordon Moore made an astonishing prediction - that every year processing power would double. Although it was corrected to a period of 18 to 24 months in 1975, this prediction has always proved accurate. Accordingly, the first Intel processor produced in 1975 was equipped with 2,300 transistors whereas the latest edition has 55 million. That means 55 million etched components crammed into an area of about a square centimetre! Today we have this extraordinary process of miniaturisation to thank for cell phones, computers and other, ever more compact electronic marvels. But where will the miniaturisation race end? What will happen when electronic etchings reach the nano-scale (a millionth of a millimetre), approaching the size of an atom? How can we even start to comprehend this nano-world, whose laws are so different from our own, human-sized world? These fascinating questions are on the programme of the 10th Wright Science Colloquia from 18 to 22 November. Five world-renowned specia...
Zhao, Lei; Gossmann, Toni I; Waxman, David
2016-03-21
The Wright-Fisher model is an important model in evolutionary biology and population genetics. It has been applied in numerous analyses of finite populations with discrete generations. It is recognised that real populations can behave, in some key aspects, as though their size that is not the census size, N, but rather a smaller size, namely the effective population size, Ne. However, in the Wright-Fisher model, there is no distinction between the effective and census population sizes. Equivalently, we can say that in this model, Ne coincides with N. The Wright-Fisher model therefore lacks an important aspect of biological realism. Here, we present a method that allows Ne to be directly incorporated into the Wright-Fisher model. The modified model involves matrices whose size is determined by Ne. Thus apart from increased biological realism, the modified model also has reduced computational complexity, particularly so when Ne⪡N. For complex problems, it may be hard or impossible to numerically analyse the most commonly-used approximation of the Wright-Fisher model that incorporates Ne, namely the diffusion approximation. An alternative approach is simulation. However, the simulations need to be sufficiently detailed that they yield an effective size that is different to the census size. Simulations may also be time consuming and have attendant statistical errors. The method presented in this work may then be the only alternative to simulations, when Ne differs from N. We illustrate the straightforward application of the method to some problems involving allele fixation and the determination of the equilibrium site frequency spectrum. We then apply the method to the problem of fixation when three alleles are segregating in a population. This latter problem is significantly more complex than a two allele problem and since the diffusion equation cannot be numerically solved, the only other way Ne can be incorporated into the analysis is by simulation. We have
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Allahyar Geramy
2015-12-01
Full Text Available Background and Aims: Cl II malocclusion is one of the most common abnormalities in human societies and using a simple, affordable and accessible treatment that can be provided by general practitioners or specialists, to prevent future malocclusion complications is vital. Cl II malocclusion treatment using functional appliances such as twin block and anterior inclined bite plan have less cost, side effects and complications compared to fixed orthodontic or orthosurgery. Until now, the dentoskeletal changes resulting from the application of twin block and anterior inclined bite plan in patients with Class II malocclusion has not been evaluated. The objective of the present study was to assess the dentoskeletal changes following the use of twin-block functional appliance and inclined anterior bite plan in the patients with class II malocclusion div 1 during mixed dentition. Materials and Methods: In this retrospective cohort trial, 60 patients with the definitive diagnosis of Class II div. 1 malocclusion having ANB>2 and FMA angel between 20 and 30 and without any previous treatment or syndrome who were treated with twin-block or inclined anterior bite plan appliance were selected and their lateral cephalometries were traced before and after treatment. Selected distance and angular landmarks were measured on the cephalograms with the good reliability (ICC=0.953 and the changes occurred in the landmarks were statistically analyzed using Student t test. Results: Due to the increased mandibular growth, most of the landmarks experienced significant changes following the treatment with twin-block and inclined bite plan (P0.05, however, SNA (P=0.04, overjet (P=0.007 and wits appraisal (P=0.004 changed differently after using the appliances. Conclusion: Despite with most similarities of both twin-block and anterior inclined bite plan to correct class II div. 1 malocclusion, Due to the advantages of anterior inclined bite plan such as less size, good
Ren, Yao; Chen, Yu; Hu, Bohan; Wu, Hui; Lai, Furao; Li, Xiaofeng
2015-12-01
An efficient microwave-assisted extraction (MAE) technique was applied to isolate total steroid saponins from Dioscorea zingiberensis C.H. Wright (DZW). The optimal extracting conditions were established as 75% ethanol as solvent, ratio of solid/liquid 1:20 (g/ml), temperature 75 °C, irradiation power 600 W and three extraction cycles of 6 min each. Scanning electron microscopy (SEM) images of DZW processed by four different extractions provided visual evidence of the disruption effect on DZW. Diosgenin was quantified by HPLC and examined further by LC-ESI/MS after acid hydrolysis. Total steroid saponins were calculated using diosgenin from total steroid saponins. The MAE procedure was optimized, validated and compared with other conventional extraction processes. This report provides a convenient technology for the extraction and quantification of total saponins of DZW combining MAE with HPLC and LC-ESI/MS for the first time. Copyright © 2015 Elsevier Inc. All rights reserved.
Energy Technology Data Exchange (ETDEWEB)
1991-10-01
This Health and Safety Plan (HSP) was developed for the Environmental Investigation of Ground-water Contamination Investigation at Wright-Patterson Air Force Base near Dayton, Ohio, based on the projected scope of work for the Phase 1, Task 4 Field Investigation. The HSP describes hazards that may be encountered during the investigation, assesses the hazards, and indicates what type of personal protective equipment is to be used for each task performed. The HSP also addresses the medical monitoring program, decontamination procedures, air monitoring, training, site control, accident prevention, and emergency response.
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Diogo Lamela
2010-01-01
Full Text Available Neste artigo propõe-se uma contribuição da teoria da vinculação na compreensão dos processos de adaptação dos adultos ao seu divórcio e como a desvinculação ao ex-cônjuge interfere na coparentalidade pós-divórcio. Este artigo formula duas hipóteses teóricas. A primeira hipótese afirma que o divórcio, enquanto processo relacional, deve ser lido como um momento de perda que germina reacções psicológicas similares às experienciadas pelos viúvos, tal como descreve Bowlby no modelo de perda da figura de vinculação, estando dependente dos estilos de vinculação dos adultos. A segunda hipótese sustenta que a coparentalidade pós-divórcio é predita pelos estilos de vinculação e pela qualidade da reorganização da vinculação dos pais. Finalmente, uma integração teórica é apresentada, operacionalizada numa proposta de investigação futura neste domínio.In this article, it is proposed the contribution of the attachment theory for understanding adults' adjustment processes to their divorce and how detachment to ex-spouse can infer in co-parenting relationships after marital dissolution. This article makes two theoretical assumptions that focus on two dimensions. The first hypothesis states that the divorce, while a relational process, should be read as a moment of loss that germinates similar psychological reactions to those experienced by widows. Bowlby describes it in his model of loss of the attachment figure as dependent on attachment styles of divorced adults. The second hypothesis argues that the post-divorce co-parenting relationships are predicted by the attachment styles and by the quality of parents' attachment reorganization. At the end, a theoretical integration is built, based on a proposal for future research in this area.
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Christian Eric Erbacher
2015-07-01
Full Text Available The National Library of Finland (NLF and the Von Wright and Wittgenstein Archives at the University of Helsinki (WWA keep the collected correspondence of Georg Henrik von Wright, Wittgenstein’s friend and successor at Cambridge and one of the three literary executors of Wittgenstein’s Nachlass. Among von Wright’s correspondence partners, Elizabeth Anscombe and Rush Rhees are of special interest to Wittgenstein scholars as the two other trustees of the Wittgenstein papers. Thus, von Wright’s collections held in Finland promise to shed light on the context of decades of editorial work that made Wittgenstein’s later philosophy available to all interested readers. In this text, we present the letters which von Wright received from Anscombe and Rhees during the first nine months after Wittgenstein’s death. This correspondence provides a vivid picture of the literary executors as persons and of their developing relationships. The presented letters are beautiful examples of what the correspondence as a whole has to offer; it depicts – besides facts of editing – the story of three philosophers, whose conversing voices unfold the human aspects of inheriting Wittgenstein’s Nachlass. Their story does not only deal with editing the papers of an eminent philosopher, but with the attempt to do justice to the man they knew, to his philosophy and to his wishes for publication.
2011-05-20
Creek during a base-wide mist net survey (BHE 2001). Radio tracking of these two bats confirmed the presence of a maternity colony in a dead slippery ... elm (Ulmus rubra) in a woodlot on the campus of Wright State University. No sightings of Indiana bats have been reported within the area of the
Fisher-Wright model with deterministic seed bank and selection.
Koopmann, Bendix; Müller, Johannes; Tellier, Aurélien; Živković, Daniel
2017-04-01
Seed banks are common characteristics to many plant species, which allow storage of genetic diversity in the soil as dormant seeds for various periods of time. We investigate an above-ground population following a Fisher-Wright model with selection coupled with a deterministic seed bank assuming the length of the seed bank is kept constant and the number of seeds is large. To assess the combined impact of seed banks and selection on genetic diversity, we derive a general diffusion model. The applied techniques outline a path of approximating a stochastic delay differential equation by an appropriately rescaled stochastic differential equation. We compute the equilibrium solution of the site-frequency spectrum and derive the times to fixation of an allele with and without selection. Finally, it is demonstrated that seed banks enhance the effect of selection onto the site-frequency spectrum while slowing down the time until the mutation-selection equilibrium is reached. Copyright © 2016 Elsevier Inc. All rights reserved.
As Bruxas no Divã: o desafio de ser criativo e ousar no ensino de artes
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Marcelo Rossa
2012-11-01
Este artigo relata o projeto “As Bruxas no Divã”, que consiste na produção de um filme no Instituto Estadual de Educação (IEE escola da rede estadual de ensino de SC. Nele introduziu-se a linguagem cinematográfica na Educação Infantil, contribuindo no processo de ensino e aprendizagem de Artes. O objetivo deste projeto foi desenvolver uma vivência dentro das diversas linguagens artísticas, bem como aguçar a reflexão sobre questões existenciais da vida. O projeto oportunizou a utilização de diversas linguagens artísticas bem como as novas tecnologias. A motivação para seu desenvolvimento foi à literatura e a produção de cinema amador infantil e se mostraram uma forma de comunicação apta a estabelecer interdisciplinaridade de várias áreas do conhecimento de forma criativa e harmoniosa.
Ryseff, Julia K; Bohn, Andrea A
2012-09-01
Osteosarcoma (OSA) is a common primary bone tumor in dogs. Demonstration of alkaline phosphatase (ALP) reactivity by tumor cells on unstained slides is useful in differentiating osteosarcoma from other types of sarcoma. However, unstained slides are not always available. The objectives of this study were to evaluate the diagnostic utility of detecting ALP expression in differentiating osteosarcoma from other sarcomas in dogs using cytologic material previously stained with Wright-Giemsa stain and to assess the sensitivity and specificity of ALP expression for diagnosing osteosarcoma using a specific protocol. Archived aspirates of histologically confirmed sarcomas in dogs that had been previously stained with Wright-Giemsa stain were treated with 5-bromo, 4-chloro, 3-indolyl phosphate/nitroblue tetrazolium (BCIP/NBT) as a substrate for ALP. Cells were evaluated for expression of ALP after incubation with BCIP/NBT for 1 hour. Sensitivity and specificity of ALP expression for diagnosis of OSA were calculated. In samples from 83 dogs, cells from 15/17 OSAs and from 4/66 tumors other than OSA (amelanotic melanoma, gastrointestinal stromal tumor, collision tumor, and anaplastic sarcoma) expressed ALP. Sensitivity and specificity of ALP expression detected using BCIP/NBT substrate applied to cells previously stained with Wright-Giemsa stain for OSA were 88 and 94%, respectively. ALP expression detected using BCIP/NBT substrate applied to previously stained cells is useful in differentiating canine OSA from other mesenchymal neoplasms. © 2012 American Society for Veterinary Clinical Pathology.
A review of Curtiss-Wright rotary engine developments with respect to general aviation potential
Jones, C.
1979-01-01
Aviation related rotary (Wankel-type) engine tests, possible growth directions and relevant developments at Curtiss-Wright have been reviewed. Automotive rotary engines including stratified charge are described and flight test results of rotary aircraft engines are presented. The current 300 HP engine prototype shows basic durability and competitive performance potential. Recent parallel developments have separately confirmed the geometric advantages of the rotary engine for direct injected unthrottled stratified charge. Specific fuel consumption equal to or better than pre- or swirl-chamber diesels, low emission and multi-fuel capability have been shown by rig tests of similar rotary engine.
Application of software technology to a future spacecraft computer design
Labaugh, R. J.
1980-01-01
A study was conducted to determine how major improvements in spacecraft computer systems can be obtained from recent advances in hardware and software technology. Investigations into integrated circuit technology indicated that the CMOS/SOS chip set being developed for the Air Force Avionics Laboratory at Wright Patterson had the best potential for improving the performance of spaceborne computer systems. An integral part of the chip set is the bit slice arithmetic and logic unit. The flexibility allowed by microprogramming, combined with the software investigations, led to the specification of a baseline architecture and instruction set.
Religion and politics in conflict: Paul Stuart Wright and the 1964 coup
Directory of Open Access Journals (Sweden)
Márcio Ananias Ferreira Vilela
2016-06-01
Full Text Available In this article, we seek to understand the implications of Paulo Stuart Wright´s political and religious action. Beginning with the civil and military coup of 1964, it suffered a strong reaction from majority sectors in the Presbyterian Church of Brazil that started to perceive him as a threat to the religious community and to society itself. The following period was marked by an intense political conflict in Brazil. This contributed for the person in question to be expelled from the Church, have his mandate as a state representative for Santa Catarina impeached, be exiled, live in clandestinity and, later on in the 1970s, be murdered by the organs of repression. Thus, his trajectory bears many similarities to those of others who marked the recent history of Brazil.
Information geometry and population genetics the mathematical structure of the Wright-Fisher model
Hofrichter, Julian; Tran, Tat Dat
2017-01-01
The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.
O envolvimento parental após a separação/divórcio Parental involvement after separation/divorce
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Luciana Suárez Grzybowski
2010-01-01
Full Text Available Apoiados no modelo ecológico-contextual e no conceito de envolvimento parental, este artigo se propõe a discutir as práticas parentais de pais e mães separados/divorciados com seus filhos. Para tanto, foram pesquisados 234 sujeitos (117 pais/117 mães com filhos em idade escolar, que responderam o Inventário de Práticas Parentais. Tal instrumento avaliou o envolvimento parental em 5 áreas: envolvimento afetivo, envolvimento didático, envolvimento social, envolvimento disciplinar e responsabilidade. Os resultados evidenciam maior envolvimento materno do que paterno com os filhos após o divórcio, tanto direto (cuidados, interação quanto indireto (monitoramento, preocupação. A coabitação com a mãe mostrou ser uma variável significativa associada ao maior envolvimento dela em atividades no espaço privado/doméstico, enquanto os pais tiveram maior envolvimento no espaço público/social. Características contextuais (coabitação, freqüência de visitas e características dos pais (ocupação, escolaridade, questões afetivo-conjugais mostraram-se fortemente associadas ao envolvimento parental após o divórcio.Based on the ecological-contextual model and on the concept of parental involvement, this article proposes to discuss the parental practices of separated/divorced fathers and mothers towards their children. In order to do so, 234 subjects (117 fathers/117 mothers with children at school were interviewed via the Parental Practices Inventory. Such instrument evaluated the parental involvement in 5 areas: affective involvement, didactic involvement, social involvement, disciplinary involvement and, responsibility. The results showed greater maternal involvement with children after the divorce: direct (care, interaction and indirect (monitoring, preoccupation. The cohabitation with the mother revealed itself as a significant variable associated to her greater involvement with activities in the private/domestic environment while
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Rohit Mehrotra
2014-01-01
Full Text Available This case report describes the esthetic and functional rehabilitation of a female patient in her mid forties having Class II Div 1 malocclusion, anterior open bite and multiple missing molars, with orthodontics and implant prosthodontics. The patient had bilaterally missing upper first and third molars and lower first and second molars. Orthodontic treatment using skeletal anchorage was performed to retract and align the upper anteriors and correct the open bite. In the upper arch, first molar spaces were closed and no prosthesis was needed. In the lower arch, the anteriors and premolars were aligned and implants were placed bilaterally to replace the missing molars and provide proper occlusion with the upper posteriors. Significant improvement in the occlusion, smile and facial esthetics was achieved. This article highlights the importance of an interdisciplinary team approach for providing optimum treatment to many adult patients.
Crossman, Molly K.; Kazdin, Alan E.
2016-01-01
Caregivers of children with autism spectrum disorder are vulnerable to overstated benefits of interventions, and such overstatements are common with interventions involving animals. This response to Wright, Hall, Hames, Hardmin, Mills, the Paws Team, and Mills' (2015) article, "Acquiring a Pet Dog Significantly Reduces Stress of Primary…
Evolutionary Game Dynamics in a Fitness-Dependent Wright-Fisher Process with Noise
International Nuclear Information System (INIS)
Quan Ji; Wang Xianjia
2011-01-01
Evolutionary game dynamics in finite size populations can be described by a fitness-dependent Wright-Fisher process. We consider symmetric 2x2 games in a well-mixed population. In our model, two parameters to describe the level of player's rationality and noise intensity in environment are introduced. In contrast with the fixation probability method that used in a noiseless case, the introducing of the noise intensity parameter makes the process an ergodic Markov process and based on the limit distribution of the process, we can analysis the evolutionary stable strategy (ESS) of the games. We illustrate the effects of the two parameters on the ESS of games using the Prisoner's dilemma games (PDG) and the snowdrift games (SG). We also compare the ESS of our model with that of the replicator dynamics in infinite size populations. The results are determined by simulation experiments. (general)
2013-02-01
AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) United States Air Force 88th...Air Base Wing Wright-Patterson Air Force Base, Ohio 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES...visitors nationwide and from foreign countries. Softball and soccer fields are located adjacent to the Museum grounds and are operated by the 88 Air
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José Manuel Fernandes
2016-11-01
Full Text Available El texto hace un análisis comparativo de las obras de Raul Lino (1879-1974, portugués, y Frank Lloyd Wright (1867-1959, de Estados Unidos- dos arquitectos (casi contemporáneos, cada uno exponente de la cultura y la sociedad de su tiempo y de su espacio de vida y de trabajo.El artículo se refiere al contexto histórico y cultural del primer periodo creativo de estos autores. En este contexto trata de las obras de John Ruskin y William Morris, creadores del Arts & Crafts, así como de las características de este movimiento artístico, de las peculiaridades del Deutscher Werkbund y de los trabajos de Sullivan y Berlage. Acerca de Lino y Wright, este artículo presenta la “comprensión del mundo” que tenían: sus temas conceptuales y arquitectónicos, así como los movimientos estéticos y culturales asociados a sus trabajos - “Casa Portuguesa” y “Arquitectura Orgánica”. Se exponen y analizan los “seis principios” de Wright y los “seis principios” de Lino -destacando los aspectos comunes de las concepciones de ambos autores. Se describen y ejemplifican, también, algunos de los temas y materiales arquitectónicos comunes en la primera fase de las obras los arquitectos. Así mismo, se estudia con mayor profundidad el diseño de obras concretas, casas, de su autoría, en sus similitudes y contrastes.
International Nuclear Information System (INIS)
Gibson, S.M.; Ogle, R.B.
1988-03-01
This report presents the results of a technical and economic assessment of available alternatives for asbestos abatement within Facility 20470 at the Wright-Patterson Air Force Base in Dayton, Ohio. Each alternative was screened on the basis of technical feasibility, environmental impact, economics, and fulfillment of the IRP goals. Four alternatives for study are: establishing a special operations and maintenance program; enclosure; encapsulation with sealants; and removal, disposal, and replacement. Each of these alternatives was assessed for capability to control the release of asbestos fibers within Facility 20470. Alternatives 1 and 4 were determined to be acceptable, while Alternatives 2 and 3 were found to be unacceptable. 2 refs., 6 figs
Louis, David N; O'Brien, Michael J; Young, Robert H
2016-09-01
During most of the nineteenth century, the discipline of pathology in Boston made substantial strides as a result of physicians and surgeons who practiced pathology on a part-time basis. The present essay tells the subsequent story, beginning in 1892, when full-time pathologists begin to staff the medical schools and hospitals of Boston. Three individuals from this era deserve special mention: William T Councilman, Frank Burr Mallory and James Homer Wright, with Councilman remembered primarily as a visionary and teacher, Mallory as a trainer of many pathologists, and Wright as a scientist. Together with S Burt Wolbach in the early-to-mid-twentieth century, these pathologists went on to train the next generation of pathologists-a generation that then populated the various hospitals that were developed in Boston in the early 1900s. This group of seminal pathologists in turn formed the diagnostically strong, academically productive, pathology departments that grew in Boston over the remainder of the twentieth century.
Padilla, Brenda Lisa
2012-01-01
This study highlights the development of a graduate training program at The Wright Institute in Berkeley, CA, which provides assessment services for undocumented immigrants seeking asylum. This program focuses on the needs of a general asylum seeking population, with a specific relevance to some of the populations that may be served in the…
DEFF Research Database (Denmark)
NIELSEN, LENE ROSTGAARD
2000-01-01
Vanilla claviculata (W. Wright) Sw. and V. barbellata Rchb.f. grow sympatrically in the southwestern part of herto Rico. At three localities in the range of the two species, individuals with flowers that appeared different from previously known species were found. To test whether these were hybrids...... the hypothesis that the individuals are hybrids, which is further augmented by interspecific pollination experiments between the putative parental species. This is the first case of natural hybridization reported in the genus Vanilla....
Way, Rupert; Lafond, François; Farmer, J. Doyne; Lillo, Fabrizio; Panchenko, Valentyn
2017-01-01
This paper considers how to optimally allocate investments in a portfolio of competing technologies. We introduce a simple model representing the underlying trade-off - between investing enough effort in any one project to spur rapid progress, and diversifying effort over many projects simultaneously to hedge against failure. We use stochastic experience curves to model the idea that investing more in a technology reduces its unit costs, and we use a mean-variance objective function to unders...
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BERNARDES Rodrigo de Castro
1997-01-01
Full Text Available A rotura de parede livre do ventrículo esquerdo (VE e a comunicação interventricular (CIV por rotura de septo são dois eventos catastróficos que podem complicar a evolução do infarto agudo do miocárdio (IAM. A oportunidade do tratamento cirúrgico, o acesso à CIV e a técnica cirúrgica ideal para o tratamento desta complicação são muito discutidos na literatura (1-5. Os resultados, porém, são quase unânimes: alta taxa de mortalidade. A rotura da parede posterior do ventrículo esquerdo pós troca da valva mitral (disjunção atrioventricular não é uma complicação rara, sendo quase sempre fatal (6, 7. O objetivo de nosso trabalho é discutir a alternativa de tratamento cirúrgico destas graves lesões, sem o manuseio direto do músculo cardíaco friável, necrozado. Desenvolvemos e testamos em animais (carneiros o dispositivo de isolamento ventricular (DIV. No período de 12/7/95 a 10/1/96, operamos 12 carneiros adultos para o implante do DIV. No primeiro período de aprendizado da técnica de implante e de desenvolvimento da prótese, operamos 7 animais, sem sucesso. No segundo período operamos 5 animais, já com o DIV completamente desenvolvido e com a técnica cirúrgica já padronizada; obtivemos sucesso com todos os animais, sobrevivendo com bom débito cardíaco, constatado ao ecocardiograma e à ventriculografia. Após 20 dias de sobrevida, os animais foram submetidos a ventriculografia e ecocardiografia. Observamos o completo isolamento da cavidade ventricular com o emprego do DIV, obtendo o tratamento provisório destas graves lesões.
Trainee Teachers' e-Learning Experiences of Computer Play
Wright, Pam
2009-01-01
Pam Wright highlights the role of technology in providing situated learning opportunities for preservice teachers to explore the role commercial computer games may have in primary education. In a study designed to assess the effectiveness of an online unit on gaming incorporated into a course on learning technologies, Wright found that thoughtful…
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Stamatović Dragana
2007-01-01
Full Text Available Introduction: Monitoring of peak expiratory flow (PEF is recommended in numerous guidelines for management of asthma. Improvements in calibration methods have demonstrated the inaccuracy of original Wright scale of peak flowmeter. A new standard, EN 13826 that was applied to peak flowmeter was adopted on 1st September 2004 by some European countries. Correction of PEF readings obtained with old type devices for measurement is possible by Dr M. Miller’s original predictive equation. Objective. Assessment of PEF correction effect on the interpretation of measurement results and management decisions. Method. In children with intermittent (35 or stable persistent asthma (75 aged 6-16 years, there were performed 8393 measurements of PEF by Vitalograph normal-range peak flowmeter with traditional Wright scale. Readings were expressed as percentage of individual best values (PB before and after correction. The effect of correction was analyzed based on The British Thoracic Society guidelines for asthma attack treatment. Results. In general, correction reduced the values of PEF (p<0.01. The highest mean percentage error (20.70% in the measured values was found in the subgroup in which PB ranged between 250 and 350 l/min. Nevertheless, the interpretation of PEF after the correction in this subgroup changed in only 2.41% of measurements. The lowest mean percentage error (15.72%, and, at the same time, the highest effect of correction on measurement results interpretation (in 22.65% readings were in children with PB above 450 l/min. In 73 (66.37% subjects, the correction changed the clinical interpretation of some values of PEF after correction. In 13 (11.8% patients, some corrected values indicated the absence or a milder degree of airflow obstruction. In 27 (24.54% children, more than 10%, and in 12 (10.93%, more than 20% of the corrected readings indicated a severe degree of asthma exacerbation that needed more aggressive treatment. Conclusion
McCaffrey, Jerrine
2001-01-01
Outlines a teaching method for Wright Morris's "A Fight Between a White Boy and a Black Boy in the Dusk of a Fall Afternoon in Omaha, Nebraska." Proposes that the story provides and opportunity to introduce stream-of-consciousness writing and to convey the significance of memory recall. (PM)
[Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio
International Nuclear Information System (INIS)
1992-04-01
This Removal Action System Design has been prepared as a Phase I Volume for the implementation of the Phase II removal action at Wright-Patterson Air Force Base (WPAFB) near Dayton, Ohio. The objective of the removal action is to prevent, to the extent practicable, the migration of ground water contaminated with chlorinated volatile organic compounds (VOCS) across the southwest boundary of Area C. The Phase 1, Volume 9 Removal Action System Design compiles the design documents prepared for the Phase II Removal Action. These documents, which are presented in Appendices to Volume 9, include: Process Design, which presents the 30 percent design for the ground water treatment system (GWTS); Design Packages 1 and 2 for Earthwork and Road Construction, and the Discharge Pipeline, respectively; no drawings are included in the appendix; Design Package 3 for installation of the Ground Water Extraction Well(s); Design Package 4 for installation of the Monitoring Well Instrumentation; and Design Package 5 for installation of the Ground Water Treatment System; this Design Package is incorporated by reference because of its size
(Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio)
Energy Technology Data Exchange (ETDEWEB)
1992-03-01
An environmental investigation of ground water conditions has been undertaken at Wright-Patterson Air Force Base (WPAFB), Ohio to obtain data to assist in the evaluation of a potential removal action to prevent, to the extent practicable, migration of the contaminated ground water across Base boundaries. Field investigations were limited to the central section of the southwestern boundary of Area C and the Springfield Pike boundary of Area B. Further, the study was limited to a maximum depth of 150 feet below grade. Three primary activities of the field investigation were: (1) installation of 22 monitoring wells, (2) collection and analysis of ground water from 71 locations, (3) measurement of ground water elevations at 69 locations. Volatile organic compounds including trichloroethylene, perchloroethylene, and/or vinyl chloride were detected in concentrations exceeding Maximum Contaminant Levels (MCL) at three locations within the Area C investigation area. Ground water at the Springfield Pike boundary of Area B occurs in two primary units, separated by a thicker-than-expected clay layers. One well within Area B was determined to exceed the MCL for trichloroethylene.
Squires, Amanda; Nasef, Nehad; Lin, Yulia; Callum, Jeannie; Khadawardi, Emad M; Drolet, Christine; Core, David; Simmons, Brian
2012-01-01
Antibodies to red cell antigens that are found at low frequency in the general population are rare causes of hemolytic disease of the newborn. To understand how to detect these cases, we provide a basic review of routine antenatal maternal antibody testing and report a case of a neonate with severe HDN caused by anti-Wright (anti-Wra), successfully managed with transfusion, phototherapy, and high-dose intravenous immunoglobulin. When hemolysis in a newborn is suspected in the absence of major blood group incompatibility or commonly detected maternal red cell antibodies, a direct antiglobulin test should be performed. A positive DAT should alert the clinician to the presence of maternal antibodies against low-incidence antigens. Antibodies to the Wra antigen are one such rare cause of HDN.
National Research Council Canada - National Science Library
1996-01-01
.... This report provides the results of the audit of two projects, valued at $5.5 million, for the closure of Gentile Air Force Station, Dayton, Ohio, and realignment to Wright-Patterson Air Force Base, Ohio, of two Defense Logistics Agency components...
International Nuclear Information System (INIS)
Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik
2017-01-01
In this paper, the stress intensity limits, Sm and St of HT-9 were built for the structural criteria of an SFR fuel assembly. Sm is obtained from the ultimate strength. As for St, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of Smt, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as Smt under the temperature about 470 .deg. C which is relatively low temperature range and over 470 .deg. C with relatively short time duration as 1000 hours. And the St is adopted as Smt at over 470 .deg. C and long time duration over 34800 hours, and over 520 .deg. C and 104 hours too. And at over 570 .deg. C and 1000 hours, and at over 630 .deg. C and 100 hours, St is also adopted for Smt. To use the present result as design criteria, a stringent examination needs to be carried out, because those are calculated from the formulae of HT-9 without an experimental validation. Therefore, an experimental work on the mechanical properties of HT-9 will be necessary.
Entrevista - Crise do Capital, disputa de destino e desafios para os trabalhadores
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Reinaldo Gonçalves
2010-05-01
Full Text Available <div>Desde 2007, temos acompanhado as notícias sobre a mais profunda crise dodiv> Air Force Research Laboratory Sensors Directorate Leadership Legacy, 1960-2011 2011-03-01 Area, Tinker AFB, Okla- homa . The mission of this 200 engineer organization was providing engineering sup- port to the current operational fleet...advanced development of ESM, ELINT, IR warning receiver technology. 1980-1984 Avionics Directorate, Air Force Wright Laboratory, WPAFB, OH - Chief...Wright Laboratory, WPAFB, OH - Deputy Chief of Electronic Warfare Division. Major technology areas included RF/ IR /EO/ COM countermeasures, stealth À Parte - Os Fundos de Pensão no Contexto da Financeirização Capitalista Directory of Open Access Journals (Sweden) Stefania Becattini Vaccaro 2010-05-01 Full Text Available <div>Este trabalho discute criticamente a expansão da previdência privadadiv> Trabalho e Moradia na Periferia: para Uma Política Urbana Economicamente Orientada Directory of Open Access Journals (Sweden) Luciana Corrêa Lago 2010-05-01 Full Text Available <div>O artigo examina as conexões entre as mudanças no mundo dodiv> Directory of Open Access Journals (Sweden) Clarissa Raposo 2010-05-01 Full Text Available <div>o texto analisa a interface entre o paradigma dos direitos da infânciadiv> Relações Internacionais, Política Social e Combate à Pobreza Directory of Open Access Journals (Sweden) Ana Paula Ornellas Mauriel 2010-05-01 Full Text Available <div>o artigo objetiva demonstrar como as políticas sociais atuais vemdiv> A Survey for Assessment of Role of Pharmacist in Community Directory of Open Access Journals (Sweden) P Kapur 2009-12-01 Full Text Available <div>Objective: To assess the role of pharmacist in community setting & consumer’s perception in National Capitaldiv> Direito à Convivência Familiar de Crianças Abrigadas: o papel do Ministério Público Directory of Open Access Journals (Sweden) Lúcia Ferreira e Sávio Bittencourt 2010-05-01 Full Text Available <div>Partindo dos estudos que demonstram que é na família estruturadadiv> Design information verification for spent fuel conditioning plants and for geological repositories International Nuclear Information System (INIS) Myatt, J.; Ward, M.D. 1995-01-01 The disposal of spent fuel is a major option for the back-end of the nuclear fuel cycle. It will require the construction, operation and eventual closure of conditioning plants and geological repositories. Consequently, a safeguards approach including Design Information Verification (DIV) must be developed for these facilities. DIV Is the examination of a completed facility to verify that it has been built to the design declared by the operator. Although DIV takes place chiefly before a plant begins routine operation, there is a continuing interest in ensuring that the plant remains as declared. That is, that the continuity of knowledge of design information is maintained during the operational phase of the plant and also post closure if necessary. A major problem with DIV of a repository is that there will be continuous structural changes during its operational life requiring advanced or special techniques for reverification. Some of these are briefly reviewed. Furthermore, since a disposal facility is expected to be operational for several decades, new mining technology may also have an impact on the DIV methods employed. Another factor in the safeguards supervision of a repository is that when the fuel has been backfilled and/or scaled in place a reassay will be a very costly exercise. The role of DIV in such novel circumstances must, therefore, be fully considered Hill, William G 2014-01-01 Although animal breeding was practiced long before the science of genetics and the relevant disciplines of population and quantitative genetics were known, breeding programs have mainly relied on simply selecting and mating the best individuals on their own or relatives' performance. This is based on sound quantitative genetic principles, developed and expounded by Lush, who attributed much of his understanding to Wright, and formalized in Fisher's infinitesimal model. Analysis at the level of individual loci and gene frequency distributions has had relatively little impact. Now with access to genomic data, a revolution in which molecular information is being used to enhance response with "genomic selection" is occurring. The predictions of breeding value still utilize multiple loci throughout the genome and, indeed, are largely compatible with additive and specifically infinitesimal model assumptions. I discuss some of the history and genetic issues as applied to the science of livestock improvement, which has had and continues to have major spin-offs into ideas and applications in other areas. Gold Medal Award for Life Achievement in Psychology in the Public Interest: Beatrice A. Wright. 2016-01-01 The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and enduring records of accomplishment in 4 areas of psychology. The 2016 recipient of Gold Medal Award for Life Achievement in Psychology in the Public Interest is Beatrice A. Wright. Dorothy W. Cantor, president of the APF, will present the APF Gold Medal Awards at the 124th Annual Convention of the American Psychological Association on August 5, 2016, at 4:00 p.m. Members of the 2016 APF Board of Trustees are: Dorothy W. Cantor, president; David H. Barlow, vice president; Melba J. T. Vasquez, secretary; Richard C. McCarty, treasurer; Elisabeth R. Straus, executive vice president/executive director; Cynthia Belar; Camilla Benbow; Rosie Phillips Bingham; Connie S. Chan; Anthony Jackson; Terence M. Keane; Archie L. Turner; W. Bruce Walsh; and Bonnie Markham and Rick McGraw, APA Board of Directors liaisons. (PsycINFO Database Record (c) 2016 APA, all rights reserved). Economia, Sociedade e Política na Construção de um Campo do Conhecimento: a Saúde Coletiva no Brasil Directory of Open Access Journals (Sweden) Silvia Gerschman 2010-05-01 Full Text Available <div>O objetivo do texto é mostrar que “Saúde Coletiva” constitui umdiv> Algunos aspectos del espectro Autista. Un trastorno inusitadamente frecuente y doloroso. Directory of Open Access Journals (Sweden) Daniel Jácome Roca 2008-07-01 Full Text Available <div data-canvas-width="403.526025">El autismo (o espectro autista es un desorden neuro-conductual –hereditario y heterogéneo-div>