Multidimensional assessment of strongly irregular voices such as in substitution voicing and spasmodic dysphonia: a compilation of own research.

Science.gov (United States)

Moerman, Mieke; Martens, Jean-Pierre; Dejonckere, Philippe

2015-04-01

This article is a compilation of own research performed during the European COoperation in Science and Technology (COST) action 2103: 'Advance Voice Function Assessment', an initiative of voice and speech processing teams consisting of physicists, engineers, and clinicians. This manuscript concerns analyzing largely irregular voicing types, namely substitution voicing (SV) and adductor spasmodic dysphonia (AdSD). A specific perceptual rating scale (IINFVo) was developed, and the Auditory Model Based Pitch Extractor (AMPEX), a piece of software that automatically analyses running speech and generates pitch values in background noise, was applied. The IINFVo perceptual rating scale has been shown to be useful in evaluating SV. The analysis of strongly irregular voices stimulated a modification of the European Laryngological Society's assessment protocol which was originally designed for the common types of (less severe) dysphonia. Acoustic analysis with AMPEX demonstrates that the most informative features are, for SV, the voicing-related acoustic features and, for AdSD, the perturbation measures. Poor correlations between self-assessment and acoustic and perceptual dimensions in the assessment of highly irregular voices argue for a multidimensional approach.

Current state of micro-robots/devices as substitutes for screening colonoscopy: assessment based on technology readiness levels.

Science.gov (United States)

Tapia-Siles, Silvia C; Coleman, Stuart; Cuschieri, Alfred

2016-02-01

Previous reports have described several candidates, which have the potential to replace colonoscopy, but to date, there is still no device capable of fully replacing flexible colonoscopy in the management of colonic disorders and for mass adult population screening for asymptomatic colorectal cancer. NASA developed the TRL methodology to describe and define the stages of development before use and marketing of any device. The definitions of the TRLS used in the present review are those formulated by "The US Department of Defense Technology Readiness Assessment Guidance" but adapted to micro-robots for colonoscopy. All the devices included are reported in scientific literature. They were identified by a systematic search in Web of Science, PubMed and IEEE Xplore amongst other sources. Devices that clearly lack the potential for full replacement of flexible colonoscopy were excluded. The technological salient features of all the devices included for assessment are described briefly, with particular focus on device propulsion. The devices are classified according to the TRL criteria based on the reported information. An analysis is next undertaken of the characteristics and salient features of the devices included in the review: wireless/tethered devices, data storage-transmission and navigation, additional functionality, residual technology challenges and clinical and socio-economical needs. Few devices currently possess the required functionality and performance to replace the conventional colonoscopy. The requirements, including functionalities which favour the development of a micro-robot platform to replace colonoscopy, are highlighted.

Information technology resources assessment

Energy Technology Data Exchange (ETDEWEB)

Stevens, D.F. [ed.

1992-01-01

This year`s Information Technology Resources Assessment (ITRA) is something of a departure from traditional practice. Past assessments have concentrated on developments in fundamental technology, particularly with respect to hardware. They form an impressive chronicle of decreasing cycle times, increasing densities, decreasing costs (or, equivalently, increasing capacity and capability per dollar spent), and new system architectures, with a leavening of operating systems and languages. Past assessments have aimed -- and succeeded -- at putting information technology squarely in the spotlight; by contrast, in the first part of this assessment, we would like to move it to the background, and encourage the reader to reflect less on the continuing technological miracles of miniaturization in space and time and more on the second- and third-order implications of some possible workplace applications of these miracles. This Information Technology Resources Assessment is intended to provide a sense of technological direction for planners in projecting the hardware, software, and human resources necessary to support the diverse IT requirements of the various components of the DOE community. It is also intended to provide a sense of our new understanding of the place of IT in our organizations.

Information technology resources assessment

Energy Technology Data Exchange (ETDEWEB)

Stevens, D.F. (ed.)

1992-01-01

This year's Information Technology Resources Assessment (ITRA) is something of a departure from traditional practice. Past assessments have concentrated on developments in fundamental technology, particularly with respect to hardware. They form an impressive chronicle of decreasing cycle times, increasing densities, decreasing costs (or, equivalently, increasing capacity and capability per dollar spent), and new system architectures, with a leavening of operating systems and languages. Past assessments have aimed -- and succeeded -- at putting information technology squarely in the spotlight; by contrast, in the first part of this assessment, we would like to move it to the background, and encourage the reader to reflect less on the continuing technological miracles of miniaturization in space and time and more on the second- and third-order implications of some possible workplace applications of these miracles. This Information Technology Resources Assessment is intended to provide a sense of technological direction for planners in projecting the hardware, software, and human resources necessary to support the diverse IT requirements of the various components of the DOE community. It is also intended to provide a sense of our new understanding of the place of IT in our organizations.

Technology assessment of thermal treatment technologies using ORWARE

International Nuclear Information System (INIS)

Assefa, G.; Eriksson, O.; Frostell, B.

2005-01-01

A technology assessment of thermal treatment technologies for wastes was performed in the form of scenarios of chains of technologies. The Swedish assessment tool, ORWARE, was used for the assessment. The scenarios of chains of thermal technologies assessed were gasification with catalytic combustion, gasification with flame combustion, incineration and landfilling. The landfilling scenario was used as a reference for comparison. The technologies were assessed from ecological and economic points of view. The results are presented in terms of global warming potential, acidification potential, eutrophication potential, consumption of primary energy carriers and welfare costs. From the simulations, gasification followed by catalytic combustion with energy recovery in a combined cycle appeared to be the most competitive technology from an ecological point of view. On the other hand, this alternative was more expensive than incineration. A sensitivity analysis was done regarding electricity prices to show which technology wins at what value of the unit price of electricity (SEK/kW h). Within this study, it was possible to make a comparison both between a combined cycle and a Rankine cycle (a system pair) and at the same time between flame combustion and catalytic combustion (a technology pair). To use gasification just as a treatment technology is not more appealing than incineration, but the possibility of combining gasification with a combined cycle is attractive in terms of electricity production. This research was done in connection with an empirical R and D work on both gasification of waste and catalytic combustion of the gasified waste at the Division of Chemical Technology, Royal Institute of Technology (KTH), Sweden

Environmental profiles on chemicals (EPC): A substitution tool i.a. used in the textile industry

DEFF Research Database (Denmark)

Larsen, Henrik Fred; Hansen, John; Laursen, Søren E.

2002-01-01

When dealing with cleaner technology and product development within industries using a lot of different chemicals, substitution is essential. In many cases substitution of hazardous chemicals with less hazardous ones will diminish the environmental impact from the industry in question. But among...... many different chemicals it can be difficult to prioritize and evaluate areas for substitution. The EPC-tool was thus developed and it has been used successfully within the Danish printing industry and the Polish textile industry. The EPC tool combines key emission and key consumption figures...... with hazard assessments of the chemicals used in production and thus creates an environmental profile of the industry, process or product in question. The preceding EPCs are used for pointing out hazardous chemicals used in relatively high quantities and therefore candidates for substitution. The EPCs created...

Effect of Colombian coal rank and its feeding technology on substitute natural gas production by entrained gasification

Directory of Open Access Journals (Sweden)

Juan Fernando Pérez-Bayer

2016-01-01

Full Text Available The effect of coal rank (from sub-bituminous to semi-anthracite and type of fuel feeding technology (slurry and dry on the production of substitute natural gas (SNG in entrained flow gasifiers is studied. Ten coals from important Colombian mines were selected. The process is modeled under thermochemical equilibrium using Aspen Plus, and its performance is evaluated in function of output parameters that include SNG heating value, Wobbe index, coal conversion efficiency, cold gas efficiency, process efficiency, global efficiency, and SNG production rate, among others. In descending order, the coal-to-SNG process improves energetically with the use of coals with: higher volatile-matter to fixed-carbon ratio, lower ash content, higher C+H/O ratio, and higher coal heating value. The overall energy efficiency of the slurry-feed technology (S-FT to produce SNG by gasification is 17% higher than the dry-feed technology (D-FT, possibly as a consequence of the higher CH4 concentration in the syngas (around 7 vol. % when the coal is fed as aqueous slurry. As the simulated SNG meets the natural gas (NG quality standards in Colombia, the substitute gaseous fuel could be directly transported through pipelines. Therefore, the coal-to-SNG process is a technically feasible and unconventional alternative for NG production.

Health technology assessment in Finland

DEFF Research Database (Denmark)

Mäkelä, Marjukka; Roine, Risto P

2010-01-01

Since the 1990s, health policy makers in Finland have been supportive of evidence-based medicine and approaches to implement its results. The Finnish Office for Health Technology Assessment (Finohta) has grown from a small start in 1995 to a medium-sized health technology assessment (HTA) agency,...... findings. The Managed Uptake of Medical Methods program links the hospital districts to agree on introduction of technologies. The Ohtanen database provides Finnish-language summaries of major assessments made in other countries.......Since the 1990s, health policy makers in Finland have been supportive of evidence-based medicine and approaches to implement its results. The Finnish Office for Health Technology Assessment (Finohta) has grown from a small start in 1995 to a medium-sized health technology assessment (HTA) agency......, with special responsibility in providing assessments to underpin national policies in screening. External evaluations enhanced the rapid growth. In the Finnish environment, decision making on health technologies is extremely decentralized, so Finohta has developed some practical tools for implementing HTA...

Risk assessment research and technology assessment

International Nuclear Information System (INIS)

Albach, H.; Schade, D.; Sinn, H.

1991-01-01

The concepts and approaches for technology assessment, the targets and scientific principles, as well as recognizable deficits and recommendations concerning purposeful strategies for the promotion of this research field require a dialog between those concerned. Conception, deficits, and the necessary measures for risk assessment research and technology assessment were discussed as well as ethical aspects. The problematic nature of using organisms altered through genetic engineering in the open land, traffic and transport, site restoration, nuclear energy, and isotope applications were subjects particularly dealt with. (DG) [de

Information Technology and Literacy Assessment.

Science.gov (United States)

Balajthy, Ernest

2002-01-01

Compares technology predictions from around 1989 with the technology of 2002. Discusses the place of computer-based assessment today, computer-scored testing, computer-administered formal assessment, Internet-based formal assessment, computerized adaptive tests, placement tests, informal assessment, electronic portfolios, information management,…

Technology Performance Level Assessment Methodology.

Energy Technology Data Exchange (ETDEWEB)

Roberts, Jesse D.; Bull, Diana L; Malins, Robert Joseph; Costello, Ronan Patrick; Aurelien Babarit; Kim Nielsen; Claudio Bittencourt Ferreira; Ben Kennedy; Kathryn Dykes; Jochem Weber

2017-04-01

The technology performance level (TPL) assessments can be applied at all technology development stages and associated technology readiness levels (TRLs). Even, and particularly, at low TRLs the TPL assessment is very effective as it, holistically, considers a wide range of WEC attributes that determine the techno-economic performance potential of the WEC farm when fully developed for commercial operation. The TPL assessment also highlights potential showstoppers at the earliest possible stage of the WEC technology development. Hence, the TPL assessment identifies the technology independent “performance requirements.” In order to achieve a successful solution, the entirety of the performance requirements within the TPL must be considered because, in the end, all the stakeholder needs must be achieved. The basis for performing a TPL assessment comes from the information provided in a dedicated format, the Technical Submission Form (TSF). The TSF requests information from the WEC developer that is required to answer the questions posed in the TPL assessment document.

Decontamination technology assessment

International Nuclear Information System (INIS)

Allen, R.P.; Konzek, G.J.; Schneider, K.R.; Smith, R.I.

1988-10-01

This study identifies and technically assesses foreign decontamination and decommissioning (D and D) technology developments that may represent significant improvements over D and D technology currently available or under development in the United States. Technology need areas for nuclear power reactor decommissioning operations were identified and prioritized using the results of past light water reactor (LWR) decommissioning studies to quantitatively evaluate the potential for reducing cost and decommissioning worker radiation dose for each major decommissioning activity. Based on these identified needs, current foreign D and D technologies of potential interest to the US were identified through personal contacts and the collection and review of an extensive body of D and D literature. These technologies were then assessed qualitatively to evaluate their uniqueness, potential for a significant reduction in D and D costs and/or worker radiation dose, development status, and other factors affecting their value and applicability to US needs. 4 refs

Market forces and technological substitutes cause fluctuations in the value of bat pest-control services for cotton.

Directory of Open Access Journals (Sweden)

Laura López-Hoffman

Full Text Available Critics of the market-based, ecosystem services approach to biodiversity conservation worry that volatile market conditions and technological substitutes will diminish the value of ecosystem services and obviate the "economic benefits" arguments for conservation. To explore the effects of market forces and substitutes on service values, we assessed how the value of the pest-control services provided by Mexican free-tailed bats (Tadarida brasiliensis mexicana to cotton production in the southwestern U.S. has changed over time. We calculated service values each year from 1990 through 2008 by estimating the value of avoided crop damage and the reduced social and private costs of insecticide use in the presence of bats. Over this period, the ecosystem service value declined by 79% ($19.09 million U.S. dollars due to the introduction and widespread adoption of Bt (Bacillus thuringiensis cotton transgenically modified to express its own pesticide, falling global cotton prices and the reduction in the number of hectares in the U.S. planted with cotton. Our results demonstrate that fluctuations in market conditions can cause temporal variation in ecosystem service values even when ecosystem function--in this case bat population numbers--is held constant. Evidence is accumulating, however, of the evolution of pest resistance to Bt cotton, suggesting that the value of bat pest-control services may increase again. This gives rise to an economic option value argument for conserving Mexican free-tailed bat populations. We anticipate that these results will spur discussion about the role of ecosystem services in biodiversity conservation in general, and bat conservation in particular.

Market forces and technological substitutes cause fluctuations in the value of bat pest-control services for cotton

Science.gov (United States)

López-Hoffman, Laura; Wiederholt, Ruscena; Sansone, Chris; Bagstad, Kenneth J.; Cryan, Paul M.; Diffendorfer, James E.; Goldstein, Joshua; LaSharr, Kelsie; Loomis, John; McCracken, Gary; Medellin, Rodrigo A.; Russell, Amy; Semmens, Darius J.

2014-01-01

Critics of the market-based, ecosystem services approach to biodiversity conservation worry that volatile market conditions and technological substitutes will diminish the value of ecosystem services and obviate the “economic benefits” arguments for conservation. To explore the effects of market forces and substitutes on service values, we assessed how the value of the pest-control services provided by Mexican free-tailed bats (Tadarida brasiliensis mexicana) to cotton production in the southwestern U.S. has changed over time. We calculated service values each year from 1990 through 2008 by estimating the value of avoided crop damage and the reduced social and private costs of insecticide use in the presence of bats. Over this period, the ecosystem service value declined by 79% ($19.09 million U.S. dollars) due to the introduction and widespread adoption of Bt (Bacillus thuringiensis) cotton transgenically modified to express its own pesticide, falling global cotton prices and the reduction in the number of hectares in the U.S. planted with cotton. Our results demonstrate that fluctuations in market conditions can cause temporal variation in ecosystem service values even when ecosystem function – in this case bat population numbers – is held constant. Evidence is accumulating, however, of the evolution of pest resistance to Bt cotton, suggesting that the value of bat pest-control services may increase again. This gives rise to an economic option value argument for conserving Mexican free-tailed bat populations. We anticipate that these results will spur discussion about the role of ecosystem services in biodiversity conservation in general, and bat conservation in particular.

ASSESSMENT OF QUALITY OF INNOVATIVE TECHNOLOGIES

Directory of Open Access Journals (Sweden)

Larisa Alexejevna Ismagilova

2016-12-01

Full Text Available We consider the topical issue of implementation of innovative technologies in the aircraft engine building industry. In this industry, products with high reliability requirements are developed and mass-produced. These products combine the latest achievements of science and technology. To make a decision on implementation of innovative technologies, a comprehensive assessment is carried out. It affects the efficiency of the innovations realization. In connection with this, the assessment of quality of innovative technologies is a key aspect in the selection of technological processes for their implementation. Problems concerning assessment of the quality of new technologies and processes of production are considered in the suggested method with respect to new positions. The developed method of assessing the quality of innovative technologies stands out for formed system of the qualimetric characteristics ensuring the effectiveness, efficiency, adaptability of innovative technologies and processes. The feature of suggested system of assessment is that it is based on principles of matching and grouping of quality indicators of innovative technologies and the characteristics of technological processes. The indicators are assessed from the standpoint of feasibility, technologies competiveness and commercial demand of products. In this paper, we discuss the example of implementing the approach of assessing the quality of the innovative technology of high-tech products such as turbine aircraft engine.

Toxicological risk at workplace and toxicity as Life Cycle Assessment impact category: Substitution of solvents as an example.

Science.gov (United States)

Schupp, Thomas; Georg, Philipp Alexander; Kirstein, Guenter

2017-01-01

Substitution of hazardous substances against less hazardous ones is a central requirement of the European Chemical Regulation REACH (European Regulation 1907/2006/EC). Hazardous substances emitted from products may not only affect the worker; drift off and distribution in the environment may finally result in exposure of the general population. This potential threat to health is covered by the impact category "toxicity" in Life Cycle Assessments. In this paper, we present a case of a substitution of volatile organic compounds in a reactive varnish, and compare the "old" formulation with the "new" formulation against health risk to the worker, and concerning the Life Cycle Assessment impact category "toxicity". The "old" formulation contained Naphtha (petroleum), hydrodesulfurized, heavy and Solvent naphtha (petroleum), light, aromatic. In the new formulation, both naphthas were replaced by n-Butylacetate, 1-Ethoxy-2-propyl acetate and Ethyl-3-ethoxy propionate. In the European Union, the naphthas are classified as mutagens and carcinogens category 1, officially. However, if benzene is below 0.1 %, registrants in the EU proposed to omit this classification, and todays naptha products on the market obviously have benzene contents below 0.1 %. On a first glance, the improvement for workplace safety introduced by the substitution, therefore, is comparatively small, as it is for toxicity in Life Cycle Assessment. However, when background knowledge concerning chemical production processes of naphtha is included, benzene below a content of 0.1 % needs to be taken into consideration, and the benefit of substitution is more obvious.

Carbon tax and substitution effects in the French industrial sector: an econometric assessment

Energy Technology Data Exchange (ETDEWEB)

Blanc, Nicolas; Callonnec, Gael (ADEME (Agence de l' environnement et de la maitrise de l' energie) (France))

2009-07-01

Within the political framework of the 'Grenelle de l'environnement' in France, the French government is studying various fiscal measures to encourage actors to reduce CO{sub 2} emissions, among others a carbon tax on every fossil energy source. The efficiency of such a measure is directly linked to the price responsiveness of the actors concerned. In this paper, after a survey of the different possible forms for an energy demand function, we focus on the secondary sector of the French economy (after having removed the industrial sub-sectors concerned with double usage or non-energy use of fuels) and assess the likelihood of industrialists shifting from one energy source to another due to a change in the relative prices of different energy sources (coal, heavy fuel oil, heating oil, natural gas and electricity), besides the improvements in energy efficiency. We conclude that with price variations of the magnitude that was observed between 1986 and 2004 the substitution effects remain low: industrialists were much more likely to improve the energy efficiency of their appliances and processes than to shift energy sources in response to a given increase in prices. Significant substitution effects, for example after applying a carbon tax, would probably only occur for greater price variations. However, the actors' response (interfuel substitution) to an increase in the price of coal is 5 to 10 times higher than for other energy sources. The study also gives us information about the speed at which industrialists adapt to variations in prices, and the results have already been used for the assessment of future fiscal measures in France.

40 CFR 721.981 - Substituted naphtholoazo-substituted naphthalenyl-substituted azonaphthol chromium complex.

Science.gov (United States)

2010-07-01

... naphthalenyl-substituted azonaphthol chromium complex. 721.981 Section 721.981 Protection of Environment...-substituted naphthalenyl-substituted azonaphthol chromium complex. (a) Chemical substance and significant new... naphtholoazo-substituted naphthalenyl-substituted azonaphthol chromium complex (PMN P-93-1631) is subject to...

Decontamination technology assessment

International Nuclear Information System (INIS)

Allen, R.P.; Konzek, G.J.; Schneider, K.J.; Smith, R.I.

1988-01-01

This study was conducted by the Pacific Northwest Laboratory (PNL) for the U.S. Department of Energy (DOE) to identify and technically assess foreign decontamination and decommissioning (D and D) technology developments that may represent significant improvements over D and D technology currently available or under development in the United States. Technology need areas for nuclear power reactor decommissioning operations were identified and prioritized using the results of past light water rector (LWR) decommissioning studies to quantitatively evaluate the potential for reducing cost and decommissioning worker radiation dose for each major decommissioning activity. Based on these identified needs, current foreign D and D technologies of potential interest to the U.S. were identified through personal contacts and the collection and review of an extensive body of D and D literature. These technologies were then assessed qualitatively to evaluate their uniqueness, potential for a significant reduction in D and D costs and/or worker radiation dose, development status, and other factors affecting their value and applicability to U.S. needs

Substitution possibilities and determinants of energy intensity for China

International Nuclear Information System (INIS)

Ma, Hengyun; Oxley, Les; Gibson, John

2009-01-01

This paper measures technological change, factor demand and inter-factor and inter-fuel substitutability measures for China. We use individual fuel price data and a two-stage approach to estimate total factor cost functions and fuel share equations. Both inter-factor and inter-fuel substitution elasticities are calculated and the change in energy intensity is decomposed into its driving forces. The results suggest that energy is substitutable for capital regionally and for labor nationally. Capital substitutes for energy more easily than labor does. Energy intensity changes vary by region but the major drivers seem to be 'budget effect' and the adoption of energy-intensive technologies, which might be embodied in high-level energy-using exports and sectors, capital investment and even old technique and equipment imports. Whether the trend in rising energy intensity continues will be significant for China and the rest of the world. (author)

Substitution possibilities and determinants of energy intensity for China

Energy Technology Data Exchange (ETDEWEB)

Ma, Hengyun [College of Economics and Management, Henan Agricultural University, 95 Wenhua Road, Zhengzhou 450002 (China); Department of Economics, University of Canterbury, Private bag 4800, Christchurch 8140 (New Zealand); Oxley, Les [Department of Economics, University of Canterbury, Private bag 4800, Christchurch 8140 (New Zealand); Gibson, John [Department of Economics, University of Waikato, Private Bag 3105, Hamilton (New Zealand)

2009-05-15

This paper measures technological change, factor demand and inter-factor and inter-fuel substitutability measures for China. We use individual fuel price data and a two-stage approach to estimate total factor cost functions and fuel share equations. Both inter-factor and inter-fuel substitution elasticities are calculated and the change in energy intensity is decomposed into its driving forces. The results suggest that energy is substitutable for capital regionally and for labor nationally. Capital substitutes for energy more easily than labor does. Energy intensity changes vary by region but the major drivers seem to be 'budget effect' and the adoption of energy-intensive technologies, which might be embodied in high-level energy-using exports and sectors, capital investment and even old technique and equipment imports. Whether the trend in rising energy intensity continues will be significant for China and the rest of the world. (author)

Approaches to Assessing Technological Literacy

Science.gov (United States)

Pearson, Greg

2006-01-01

It is the conclusion of the Committee on Assessing Technological Literacy, a study panel appointed by the National Academy of Engineering and the National Research Council, that very little is known about what children or adults know, can do, and believe about technology. This is because the state of assessment related to technology--or, …

Ion exchange technology assessment report

International Nuclear Information System (INIS)

Duhn, E.F.

1992-01-01

In the execution of its charter, the SRS Ion Exchange Technology Assessment Team has determined that ion exchange (IX) technology has evolved to the point where it should now be considered as a viable alternative to the SRS reference ITP/LW/PH process. The ion exchange media available today offer the ability to design ion exchange processing systems tailored to the unique physical and chemical properties of SRS soluble HLW's. The technical assessment of IX technology and its applicability to the processing of SRS soluble HLW has demonstrated that IX is unquestionably a viable technology. A task team was chartered to evaluate the technology of ion exchange and its potential for replacing the present In-Tank Precipitation and proposed Late Wash processes to remove Cs, Sr, and Pu from soluble salt solutions at the Savannah River Site. This report documents the ion exchange technology assessment and conclusions of the task team

Dynamic integrated assessment of bioenergy technologies for energy production utilizing agricultural residues: An input–output approach

International Nuclear Information System (INIS)

Song, Junnian; Yang, Wei; Higano, Yoshiro; Wang, Xian’en

2015-01-01

Highlights: • A dynamic input–output model is developed with bioenergy technologies complemented. • Availability of agricultural residues for bioenergy technologies is evaluated. • Trends in electricity and biofuel production are simulated dynamically. • Net profit and GHG mitigation contribution of bioenergy technologies are assessed. • Combustion power generation and briquette fuel are more advantageous. - Abstract: In order to facilitate regional agricultural residue utilization for energy production through bioenergy technologies, a dynamic input–output model is developed to estimate and assess the energy, economic and environmental performances of industrialization of five bioenergy technologies within a 15-year time horizon. Electricity and solid, gaseous and liquid biofuels are energy products of bioenergy technologies. Bioenergy technologies are complemented into regional input–output framework and combined with socioeconomic activities aided by their bottom-up economic and energy parameters. The simulation results for the target area indicate that the agricultural residues available for bioenergy technologies could amount to 55.16 million t, facilitating to 8.38 million t coal-equivalent bioenergy production by 2025. A 3.1% net reduction in accumulative greenhouse gas emission compared with the “business as usual” case could be achieved owing to substitution of fossil energy with electricity and biofuels produced by bioenergy technologies. From energy production, economic benefits and greenhouse gas mitigation three aspects integratedly, direct-combustion power generation and briquette fuel are more advantageous in the target area. The quantified energy, economic and environmental performances of bioenergy technologies are expected to give recommendations for their industrial development.

Substituting missing data in compositional analysis

Energy Technology Data Exchange (ETDEWEB)

Real, Carlos, E-mail: carlos.real@usc.es [Area de Ecologia, Departamento de Biologia Celular y Ecologia, Escuela Politecnica Superior, Universidad de Santiago de Compostela, 27002 Lugo (Spain); Angel Fernandez, J.; Aboal, Jesus R.; Carballeira, Alejo [Area de Ecologia, Departamento de Biologia Celular y Ecologia, Facultad de Biologia, Universidad de Santiago de Compostela, 15782 Santiago de Compostela (Spain)

2011-10-15

Multivariate analysis of environmental data sets requires the absence of missing values or their substitution by small values. However, if the data is transformed logarithmically prior to the analysis, this solution cannot be applied because the logarithm of a small value might become an outlier. Several methods for substituting the missing values can be found in the literature although none of them guarantees that no distortion of the structure of the data set is produced. We propose a method for the assessment of these distortions which can be used for deciding whether to retain or not the samples or variables containing missing values and for the investigation of the performance of different substitution techniques. The method analyzes the structure of the distances among samples using Mantel tests. We present an application of the method to PCDD/F data measured in samples of terrestrial moss as part of a biomonitoring study. - Highlights: > Missing values in multivariate data sets must be substituted prior to analysis. > The substituted values can modify the structure of the data set. > We developed a method to estimate the magnitude of the alterations. > The method is simple and based on the Mantel test. > The method allowed the identification of problematic variables in a sample data set. - A method is presented for the assessment of the possible distortions in multivariate analysis caused by the substitution of missing values.

ASSESSMENT OF GALLIUM OXIDE TECHNOLOGY

Science.gov (United States)

2017-08-01

AFRL-RY-WP-TR-2017-0167 ASSESSMENT OF GALLIUM OXIDE TECHNOLOGY Burhan Bayraktaroglu Devices for Sensing Branch Aerospace...TITLE AND SUBTITLE ASSESSMENT OF GALLIUM OXIDE TECHNOLOGY 5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER N/A 6...report summarizes the current status of the Ga2O3 technology based on published results on theoretical electronic structure, materials growth, and

Assessing for Technological Literacy

Science.gov (United States)

Engstrom, Daniel E.

2004-01-01

Designing standards-based assessment is a key component of a quality technology education program. For students to become technologically literate, it is important that the teacher understands how to measure student understandings and abilities in the study of technology. This article is written to help teachers and teacher educators recognize the…

Beyond Simulation As Substitution: From Mixed Reality To Ego-Shots

OpenAIRE

Alberich Pascual, Jordi; San Cornelio Esquerdo, Gemma

2012-01-01

The dominant formulation of simulation theories in the 1980s and 1990s (Baudrillard, Lévy et al.) suggested a theoretical and technological paradigm based on the impersonation (when not substitution) of the real by the virtual. The present article explores the recent emergence of an integrated, mixed or altered conception of virtualisation in regards to the real, but no longer a substitutive one: a conception that is related to a significant set of digital technologies and current audiovisual...

SUSTAINABILITY LOGISTICS BASING SCIENCE AND TECHNOLOGY OBJECTIVE DEMONSTRATION; SELECTED TECHNOLOGY ASSESSMENT

Science.gov (United States)

2018-03-22

BASING SCIENCE AND TECHNOLOGY OBJECTIVE – DEMONSTRATION; SELECTED TECHNOLOGY ASSESSMENT by Gregg J. Gildea Paul D. Carpenter Benjamin J...Campbell William F. Harris* Michael A. McCluskey** and José A. Miletti*** *General Dynamics Information Technology Fairfax, VA 22030 **Maneuver...SCIENCE AND TECHNOLOGY OBJECTIVE – DEMONSTRATION; SELECTED TECHNOLOGY ASSESSMENT 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

Life cycle assessment of thermal Waste-to-Energy technologies: Review and recommendations

DEFF Research Database (Denmark)

Astrup, Thomas Fruergaard; Tonini, Davide; Turconi, Roberto

2015-01-01

composition, technology, gas cleaning, energy recovery, residue management, and inventory data), and (iii) modeling principles (e.g. energy/mass calculation principles, energy substitution, inclusion of capital goods and uncertainty evaluation). Very few of the published studies provided full and transparent...

Identifying and Assessing Life-Cycle-Related Critical Technology Elements (CTEs) for Technology Readiness Assessments (TRAs)

National Research Council Canada - National Science Library

Mandelbaum, Jay

2006-01-01

.... Because these technologies are not emphasized in the current Technology Readiness Assessment (TRA) process this document is intended to improve the focus on life-cycle-related technologies in TRAs...

History of the international societies in health technology assessment: International Society for Technology Assessment in Health Care and Health Technology Assessment International.

Science.gov (United States)

Banta, David; Jonsson, Egon; Childs, Paul

2009-07-01

The International Society for Technology Assessment in Health Care (ISTAHC) was formed in 1985. It grew out of the increasing awareness of the international dimensions of health technology assessment (HTA) and the need for new communication methods at the international level. The main function of ISTAHC was to present an annual conference, which gradually grew in size, and also to generally improve in quality from to year. ISTAHC overextended itself financially early in the first decade of the 2000s and had to cease its existence. A new society, Health Technology Assessment international (HTAi), based on many of the same ideas and people, grew up beginning in the year 2003. The two societies have played a large role in making the field of HTA visible to people around the world and providing a forum for discussion on the methods and role of HTA.

Substituting missing data in compositional analysis

International Nuclear Information System (INIS)

Real, Carlos; Angel Fernandez, J.; Aboal, Jesus R.; Carballeira, Alejo

2011-01-01

Multivariate analysis of environmental data sets requires the absence of missing values or their substitution by small values. However, if the data is transformed logarithmically prior to the analysis, this solution cannot be applied because the logarithm of a small value might become an outlier. Several methods for substituting the missing values can be found in the literature although none of them guarantees that no distortion of the structure of the data set is produced. We propose a method for the assessment of these distortions which can be used for deciding whether to retain or not the samples or variables containing missing values and for the investigation of the performance of different substitution techniques. The method analyzes the structure of the distances among samples using Mantel tests. We present an application of the method to PCDD/F data measured in samples of terrestrial moss as part of a biomonitoring study. - Highlights: → Missing values in multivariate data sets must be substituted prior to analysis. → The substituted values can modify the structure of the data set. → We developed a method to estimate the magnitude of the alterations. → The method is simple and based on the Mantel test. → The method allowed the identification of problematic variables in a sample data set. - A method is presented for the assessment of the possible distortions in multivariate analysis caused by the substitution of missing values.

Mitigation assessment results and priorities in China

Energy Technology Data Exchange (ETDEWEB)

Wu Zongxin; Wei Zhihong [Tsinghua Univ., Beijing (China)

1996-12-31

In this paper energy related CO2 emission projections of China by 2030 are given. CO2 mitigation potential and technology options in main fields of energy conservation and energy substitution are analyzed. CO2 reduction costs of main mitigation technologies are estimated and the AHP approach is used for helping assessment of priority technologies.

Establishment of Health Technology Assessment in Iran

Directory of Open Access Journals (Sweden)

Shila Doaee

2012-06-01

Full Text Available Objective: Health Technology Assessment (HTA aims at informing healthcare policymakers, managers and practitioners of the "clinical consequences, but also the economic, ethical, and other social implications of the diffusion and use of a specific procedure or technique on medical practice". So considering the policy-oriented nature of HTA that calls for a close integration into the functioning and governance of health systems the present study focuses on executive processes and function of the HTA office of Iran.Materials and methods: Data of this review study were collected through documented sources and observations from 2007 to 2010.Results: Health Technology Assessment began its activities as a secretariat in the Deputy of Health in 2007 and it continues as a Health Technology Assessment Office at the Management of Health Technology Assessment, Standardization, and Tariff at the Deputy of curative affairs of MOHME in the beginning of 2010.14 Technology of modern medical equipment and 8 pharmaceutical medicine are assessed, Now many of measures for HTA establishment  such as cooperation National Institute of Health Research (NIHR, Holding scientific committee meetings, Establishing  the  Master's degree of  health technology assessment ,Building capacities for health technology assessment through education in major universities of the country.Conclusion: pay attention to health technology assessment, selection and application of proper technologies in the frameworks of policy-making and managerial strategies and make efforts to develop it with the support of the governmental in Iran is necessary.

Multisensory integration, sensory substitution and visual rehabilitation

DEFF Research Database (Denmark)

Proulx, Michael J; Ptito, Maurice; Amedi, Amir

2014-01-01

Sensory substitution has advanced remarkably over the past 35 years since first introduced to the scientific literature by Paul Bach-y-Rita. In this issue dedicated to his memory, we describe a collection of reviews that assess the current state of neuroscience research on sensory substitution...

Superconducting Technology Assessment

National Research Council Canada - National Science Library

2005-01-01

This Superconducting Technology Assessment (STA) has been conducted by the National Security Agency to address the fundamental question of a potential replacement for silicon complementary metal oxide semiconductor (CMOS...

Comparisons of the Composition of Tobacco Smoke and the Smokes from Various Tobacco Substitutes

Directory of Open Access Journals (Sweden)

Green CR

2014-12-01

Full Text Available By the late 1970s, eight technologies in the design of a ‘less hazardous’ cigarette were classified as significant. The eight included: The tobacco blend, the filter tip, filter-tip additives, reconstituted tobacco sheet, paper additives, air dilution via paper porosity, expanded tobacco, and air dilution via filter-tip perforation. In addition to these eight cigarette-design technologies was another proposed technology which involved the incorporation of a substitute for some or all of the tobacco in the cigarette filler. Despite considerable research and development (R&D effort on various tobacco substitutes that indicated the replacements in most instances fulfilled the definition of a ‘less hazardous’ cigarette with regard to the chemical and biological properties of their mainstream smoke, tobacco substitute-containing cigarettes failed to attain consumer acceptability. As a result, several marketed products containing tobacco substitutes had an extremely brief tenure in the marketplace. Outlined herein is a summary of some detailed research conducted on the composition of the mainstream smokes from cigarettes containing either all-substitute filler or fillers comprising various substitute and tobacco mixtures as well as an all-tobacco cigarette.

Technologies Assessing Limb Bradykinesia in Parkinson's Disease.

Science.gov (United States)

Hasan, Hasan; Athauda, Dilan S; Foltynie, Thomas; Noyce, Alastair J

2017-01-01

The MDS-UPDRS (Movement Disorders Society - Unified Parkinson's Disease Rating Scale) is the most widely used scale for rating impairment in PD. Subscores measuring bradykinesia have low reliability that can be subject to rater variability. Novel technological tools can be used to overcome such issues. To systematically explore and describe the available technologies for measuring limb bradykinesia in PD that were published between 2006 and 2016. A systematic literature search using PubMed (MEDLINE), IEEE Xplore, Web of Science, Scopus and Engineering Village (Compendex and Inspec) databases was performed to identify relevant technologies published until 18 October 2016. 47 technologies assessing bradykinesia in PD were identified, 17 of which offered home and clinic-based assessment whilst 30 provided clinic-based assessment only. Of the eligible studies, 7 were validated in a PD patient population only, whilst 40 were tested in both PD and healthy control groups. 19 of the 47 technologies assessed bradykinesia only, whereas 28 assessed other parkinsonian features as well. 33 technologies have been described in additional PD-related studies, whereas 14 are not known to have been tested beyond the pilot phase. Technology based tools offer advantages including objective motor assessment and home monitoring of symptoms, and can be used to assess response to intervention in clinical trials or routine care. This review provides an up-to-date repository and synthesis of the current literature regarding technology used for assessing limb bradykinesia in PD. The review also discusses the current trends with regards to technology and discusses future directions in development.

Information Technology Resources Assessment

Energy Technology Data Exchange (ETDEWEB)

1993-04-01

The Information Technology Resources Assessment (ITRA) is being published as a companion document to the Department of Energy (DOE) FY 1994--FY 1998 Information Resources Management Long-Range Plan. This document represents a collaborative effort between the Office of Information Resources Management and the Office of Energy Research that was undertaken to achieve, in part, the Technology Strategic Objective of IRM Vision 21. An integral part of this objective, technology forecasting provides an understanding of the information technology horizon and presents a perspective and focus on technologies of particular interest to DOE program activities. Specifically, this document provides site planners with an overview of the status and use of new information technology for their planning consideration.

Technological and life cycle assessment of organics processing odour control technologies

Energy Technology Data Exchange (ETDEWEB)

Bindra, Navin [School of Engineering, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G2W1 (Canada); Dubey, Brajesh, E-mail: bkdubey@civil.iitkgp.ernet.in [School of Engineering, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G2W1 (Canada); Environmental Engineering Division, Department of Civil Engineering, Indian Institute of Technology, Kharagpur, West Bengal 721302 (India); Dutta, Animesh [School of Engineering, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G2W1 (Canada)

2015-09-15

As more municipalities and communities across developed world look towards implementing organic waste management programmes or upgrading existing ones, composting facilities are emerging as a popular choice. However, odour from these facilities continues to be one of the most important concerns in terms of cost & effective mitigation. This paper provides a technological and life cycle assessment of some of the different odour control technologies and treatment methods that can be implemented in organics processing facilities. The technological assessment compared biofilters, packed tower wet scrubbers, fine mist wet scrubbers, activated carbon adsorption, thermal oxidization, oxidization chemicals and masking agents. The technologies/treatment methods were evaluated and compared based on a variety of operational, usage and cost parameters. Based on the technological assessment it was found that, biofilters and packed bed wet scrubbers are the most applicable odour control technologies for use in organics processing faculties. A life cycle assessment was then done to compare the environmental impacts of the packed-bed wet scrubber system, organic (wood-chip media) bio-filter and inorganic (synthetic media) bio-filter systems. Twelve impact categories were assessed; cumulative energy demand (CED), climate change, human toxicity, photochemical oxidant formation, metal depletion, fossil depletion, terrestrial acidification, freshwater eutrophication, marine eutrophication, terrestrial eco-toxicity, freshwater eco-toxicity and marine eco-toxicity. The results showed that for all impact categories the synthetic media biofilter had the highest environmental impact, followed by the wood chip media bio-filter system. The packed-bed system had the lowest environmental impact for all categories. - Highlights: • Assessment of odour control technologies for organics processing facilities. • Comparative life cycle assessment of three odour control technologies was conducted

Smart Phones and their Substitutes

DEFF Research Database (Denmark)

Bødker, Mads; Gimpel, Gregory; Hedman, Jonas

2009-01-01

Drawing on data from a longitudinal field study, this paper investigates the influence of existing, better and stand-alone technology substitutes on the use of smart phones. By applying prospect theory, media richness theory, and business model literature, the purpose of this paper is to improve...... our understanding of the role of substitutes, device content fit issues, and implications for business models by asking the question: What is an effective business model to address the relationship between user preference and the fit of the smart phone and everyday task? The field study data suggest...... the need for business models to recognize that adoption decisions are reference-dependent and strongly influenced by the fit between task and smart phone....

Technology assessment of solar energy utilization

Science.gov (United States)

Jaeger, F.

1985-11-01

The general objectives and methods of Technology Assessment (TA) are outlined. Typical analysis steps of a TA for solar energy are reviewed: description of the technology and its further development; identification of impact areas; analysis of boundary conditions and definition of scenarios; market penetration of solar technologies; projection of consequences in areas of impact; and assessment of impacts and identification of options for action.

Substituting environmentally relevant flame retardants: assessment fundamentals. Vol. 1: results and summary overview; Erarbeitung von Bewertungsgrundlagen zur Substitution umweltrelevanter Flammschutzmittel. Bd. 1: Ergebnisse und zusammenfassende Uebersicht

Energy Technology Data Exchange (ETDEWEB)

Leisewitz, A.; Kruse, H.; Schramm, E.

2001-04-01

The study examines the status, trends and alternatives (substitution and reduction potentials) in the use of flame retardants in selected product sectors: construction; electronics and electrical engineering; rail vehicles; textiles/upholstery. In addition, the study characterises thirteen flame retardants in terms of material flows, applications and toxicology/ecotoxicology. Vol. I: Summary overview of flame retardant applications in Germany in 1999/2000; characterisation of 13 flame retardants in terms of substance properties and application-specific characteristics, range of applications and quantities; derivation of assessment fundamentals for flame retardants, focussing on toxicology/ecotoxicology, suitability for closed-loop substance management, and potential for substitution and reduction; summary assessment of 13 flame retardants; summary overview of flame retardant applications. Vol. II: Analysis of flame retardant applications (state of the art, trends, alternatives) in: unsaturated polyester (UP) resins (rail vehicles); polyurethane (PU) insulating foams and one component foams (OCF) (construction sector); plastics for generic uses in electronic and electrical equipment, in casings for electronic and electrical equipment and in printed circuit boards (electronics/electrical engineering); and in upholstery and mattresses (textile applications). Vol. III: Toxicological/ecotoxicological profiles of substances: Decabromodiphenyl oxide; Tetrabromobisphenol A; Bis[pentabromophenyl]ethane; Hexabromocyclodo-decane, Tris[chloropropyl]phosphate, Resorcinol-bis-diphenylphosphate; N-Hydroxymethyl-3-dimethylphosphonopropionamide, Red phosphorus, Ammonium polyphosphate, Melamin cyanurate, Aluminiumtrihydroxide, Sodium borate decahydrate, Antimony trioxide. (orig.) [German] Untersucht werden Stand, Trends und Alternativen (Substitutions- und Minderungspotentiale) beim Einsatz von Flammschutzmitteln (FSM) in ausgewaehlten Produkten aus: Baubereich, Elektrotechnik

Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment.

Science.gov (United States)

Panzitta, Michele; Bruno, Giorgio; Giovagnoli, Stefano; Mendicino, Francesca R; Ricci, Maurizio

2015-11-30

Health Technology Assessment (HTA) is a multidisciplinary health political instrument that evaluates the consequences, mainly clinical and economical, of a health care technology; the HTA aim is to produce and spread information on scientific and technological innovation for health political decision making process. Drug delivery systems (DDS), such as nanocarriers, are technologically complex but they have pivotal relevance in therapeutic innovation. The HTA process, as commonly applied to conventional drug evaluation, should upgrade to a full pharmaceutical assessment, considering the DDS complexity. This is useful to study more in depth the clinical outcome and to broaden its critical assessment toward pharmaceutical issues affecting the patient and not measured by the current clinical evidence approach. We draw out the expertise necessary to perform the pharmaceutical assessment and we propose a format to evaluate the DDS technological topics such as formulation and mechanism of action, physicochemical characteristics, manufacturing process. We integrated the above-mentioned three points in the Evidence Based Medicine approach, which is data source for any HTA process. In this regard, the introduction of a Pharmaceutics Expert figure in the HTA could be fundamental to grant a more detailed evaluation of medicine product characteristics and performances and to help optimizing DDS features to overcome R&D drawbacks. Some aspects of product development, such as manufacturing processes, should be part of the HTA as innovative manufacturing processes allow new products to reach more effectively patient bedside. HTA so upgraded may encourage resource allocating payers to invest in innovative technologies and providers to focus on innovative material properties and manufacturing processes, thus contributing to bring more medicines in therapy in a sustainable manner. Copyright © 2015 Elsevier B.V. All rights reserved.

Assessing a Currency Substitution Persistency in the Western Balkan Region

Directory of Open Access Journals (Sweden)

Mehmed Ganić

2017-12-01

Full Text Available The study aims to examine the euroization phenomenon in seven Western Balkan countries (Albania, Bosnia and Herzegovina, Bulgaria, Croatia, Romania, Serbia and Macedonia between 2000 and 2015 and a number of –specific challenges faced by the region. More precisely, the paper analyzes the impact of the latest global financial crisis on the extent of currency substitution persistency by exploring the trends before, in wake of the financial crisis, and after the financial crisis. The study employed several indicators as a proxy variable for measuring of the overall level of currency substitution or euroization and cross country analysis in selected countries (liability euroization, credit euroization and deposit euroization and asset substitution- overall euroization index. Finally, the study found that deposit euroisation, credit euroization, and liabilities euroization in seven Western Balkan countries is still high with relatively high degree of heterogeneity. In some countries of the Western Balkan region the process of euroisation was further intensified in spite of the consequences of the latest global financial crises, while in the other ones the crisis years were marked by the trend of de-euroisation. In overall, this study does not find any significant evidence on significantly increases or decreases in currency substitution at the region sub-samples. Finally, Student t-test results indicate that there is no significant difference in means of before, in wake and after the financial crises at level of Western Balkan region.

ASSESSMENT OF QUALITY OF INNOVATIVE TECHNOLOGIES

OpenAIRE

Larisa Alexejevna Ismagilova; Nadegda Aleksandrovna Sukhova

2016-01-01

We consider the topical issue of implementation of innovative technologies in the aircraft engine building industry. In this industry, products with high reliability requirements are developed and mass-produced. These products combine the latest achievements of science and technology. To make a decision on implementation of innovative technologies, a comprehensive assessment is carried out. It affects the efficiency of the innovations realization. In connection with this, the assessment of qu...

Institutionalising health technology assessment: establishing the Medical Technology Assessment Board in India.

Science.gov (United States)

Downey, Laura E; Mehndiratta, Abha; Grover, Ashoo; Gauba, Vijay; Sheikh, Kabir; Prinja, Shankar; Singh, Ravinder; Cluzeau, Francoise A; Dabak, Saudamini; Teerawattananon, Yot; Kumar, Sanjiv; Swaminathan, Soumya

2017-01-01

India is at crossroads with a commitment by the government to universal health coverage (UHC), driving efficiency and tackling waste across the public healthcare sector. Health technology assessment (HTA) is an important policy reform that can assist policy-makers to tackle inequities and inefficiencies by improving the way in which health resources are allocated towards cost-effective, appropriate and feasible interventions. The equitable and efficient distribution of health budget resources, as well as timely uptake of good value technologies, are critical to strengthen the Indian healthcare system. The government of India is set to establish a Medical Technology Assessment Board to evaluate existing and new health technologies in India, assist choices between comparable technologies for adoption by the healthcare system and improve the way in which priorities for health are set. This initiative aims to introduce a more transparent, inclusive, fair and evidence-based process by which decisions regarding the allocation of health resources are made in India towards the ultimate goal of UHC. In this analysis article, we report on plans and progress of the government of India for the institutionalisation of HTA in the country. Where India is home to one-sixth of the global population, improving the health services that the population receives will have a resounding impact not only for India but also for global health.

Technology Assessment Need: Review on Attractiveness and Competitiveness

Science.gov (United States)

Salwa Sait, Siti; Merlinda Muharam, Farrah; Chin, Thoo Ai; Sulaiman, Zuraidah

2017-06-01

Technology assessment is crucial in managing technology for the purpose of technology exploitation. With business environment continuously changing, firms have to address this issue critically as technology is considered one of the important elements to evaluate performance and gain competitive advantage. Missteps in deciding the best technology to be developed, employed or maintained would cost the firm overall value. To fulfil the need of finding the appropriate scale to assess suitable technology, this paper summarizes that technology assessment (TA) should cover two main aspects, namely technology attractiveness and competitiveness. These components are seen capable to link the scale suggested towards evaluation of financial and non-financial performance towards competitive advantage.

What influences the choice of assessment methods in health technology assessments? Statistical analysis of international health technology assessments from 1989 to 2002.

Science.gov (United States)

Draborg, Eva; Andersen, Christian Kronborg

2006-01-01

Health technology assessment (HTA) has been used as input in decision making worldwide for more than 25 years. However, no uniform definition of HTA or agreement on assessment methods exists, leaving open the question of what influences the choice of assessment methods in HTAs. The objective of this study is to analyze statistically a possible relationship between methods of assessment used in practical HTAs, type of assessed technology, type of assessors, and year of publication. A sample of 433 HTAs published by eleven leading institutions or agencies in nine countries was reviewed and analyzed by multiple logistic regression. The study shows that outsourcing of HTA reports to external partners is associated with a higher likelihood of using assessment methods, such as meta-analysis, surveys, economic evaluations, and randomized controlled trials; and with a lower likelihood of using assessment methods, such as literature reviews and "other methods". The year of publication was statistically related to the inclusion of economic evaluations and shows a decreasing likelihood during the year span. The type of assessed technology was related to economic evaluations with a decreasing likelihood, to surveys, and to "other methods" with a decreasing likelihood when pharmaceuticals were the assessed type of technology. During the period from 1989 to 2002, no major developments in assessment methods used in practical HTAs were shown statistically in a sample of 433 HTAs worldwide. Outsourcing to external assessors has a statistically significant influence on choice of assessment methods.

PACS/IMAC technology assessment

OpenAIRE

Schilling, Ronald B.

1997-01-01

According to Peter Ogle of Digital Imaging (San Francisco, CA), “Radiologists should help identify common values for the use of information technology in medicine.” Achieving a set of common values often requires a framework for organizing the thought process involved. That is the focus of this article in addressing the subject of picture archiving and communication system (PACS) technology assessment.

Technologies Assessing Limb Bradykinesia in Parkinson’s Disease

Science.gov (United States)

Hasan, Hasan; Athauda, Dilan S.; Foltynie, Thomas; Noyce, Alastair J.

2017-01-01

Background: The MDS-UPDRS (Movement Disorders Society – Unified Parkinson’s Disease Rating Scale) is the most widely used scale for rating impairment in PD. Subscores measuring bradykinesia have low reliability that can be subject to rater variability. Novel technological tools can be used to overcome such issues. Objective: To systematically explore and describe the available technologies for measuring limb bradykinesia in PD that were published between 2006 and 2016. Methods: A systematic literature search using PubMed (MEDLINE), IEEE Xplore, Web of Science, Scopus and Engineering Village (Compendex and Inspec) databases was performed to identify relevant technologies published until 18 October 2016. Results: 47 technologies assessing bradykinesia in PD were identified, 17 of which offered home and clinic-based assessment whilst 30 provided clinic-based assessment only. Of the eligible studies, 7 were validated in a PD patient population only, whilst 40 were tested in both PD and healthy control groups. 19 of the 47 technologies assessed bradykinesia only, whereas 28 assessed other parkinsonian features as well. 33 technologies have been described in additional PD-related studies, whereas 14 are not known to have been tested beyond the pilot phase. Conclusion: Technology based tools offer advantages including objective motor assessment and home monitoring of symptoms, and can be used to assess response to intervention in clinical trials or routine care. This review provides an up-to-date repository and synthesis of the current literature regarding technology used for assessing limb bradykinesia in PD. The review also discusses the current trends with regards to technology and discusses future directions in development. PMID:28222539

Health technology assessment. Evaluation of biomedical innovative technologies.

Science.gov (United States)

Turchetti, Giuseppe; Spadoni, Enza; Geisler, Eliezer Elie

2010-01-01

This article describes health technology assessment (HTA) as an evaluation tool that applies systematic methods of inquiry to the generation and use of health technologies and new products. The focus of this article is on the contributions of HTA to the management of the new product development effort in the biomedical organization. Critical success factors (CSFs) are listed, and their role in assessing success is defined and explained. One of the conclusions of this article is that HTA is a powerful tool for managers in the biomedical sector, allowing them to better manage their innovation effort in their continuing struggle for competitiveness and survival.

Independent Assessment of Technology Characterizations to Support the Biomass Program Annual State-of-Technology Assessments

Energy Technology Data Exchange (ETDEWEB)

Yeh, B.

2011-03-01

This report discusses an investigation that addressed two thermochemical conversion pathways for the production of liquid fuels and addressed the steps to the process, the technology providers, a method for determining the state of technology and a tool to continuously assess the state of technology. This report summarizes the findings of the investigation as well as recommendations for improvements for future studies.

Technology Assessment and Roadmap for the Emergency Radiation Dose Assessment Program

International Nuclear Information System (INIS)

Turteltaub, K W; Hartman-Siantar, C; Easterly, C; Blakely, W

2005-01-01

A Joint Interagency Working Group (JIWG) under the auspices of the Department of Homeland Security Office of Research and Development conducted a technology assessment of emergency radiological dose assessment capabilities as part of the overall need for rapid emergency medical response in the event of a radiological terrorist event in the United States. The goal of the evaluation is to identify gaps and recommend general research and development needs to better prepare the Country for mitigating the effects of such an event. Given the capabilities and roles for responding to a radiological event extend across many agencies, a consensus of gaps and suggested development plans was a major goal of this evaluation and road-mapping effort. The working group consisted of experts representing the Departments of Homeland Security, Health and Human Services (Centers for Disease Control and the National Institutes of Health), Food and Drug Administration, Department of Defense and the Department of Energy's National Laboratories (see appendix A for participants). The specific goals of this Technology Assessment and Roadmap were to: (1) Describe the general context for deployment of emergency radiation dose assessment tools following terrorist use of a radiological or nuclear device; (2) Assess current and emerging dose assessment technologies; and (3) Put forward a consensus high-level technology roadmap for interagency research and development in this area. This report provides a summary of the consensus of needs, gaps and recommendations for a research program in the area of radiation dosimetry for early response, followed by a summary of the technologies available and on the near-term horizon. We then present a roadmap for a research program to bring present and emerging near-term technologies to bear on the gaps in radiation dose assessment and triage. Finally we present detailed supporting discussion on the nature of the threats we considered, the status of technology

Technology Assessment and Roadmap for the Emergency Radiation Dose Assessment Program

Energy Technology Data Exchange (ETDEWEB)

Turteltaub, K W; Hartman-Siantar, C; Easterly, C; Blakely, W

2005-10-03

A Joint Interagency Working Group (JIWG) under the auspices of the Department of Homeland Security Office of Research and Development conducted a technology assessment of emergency radiological dose assessment capabilities as part of the overall need for rapid emergency medical response in the event of a radiological terrorist event in the United States. The goal of the evaluation is to identify gaps and recommend general research and development needs to better prepare the Country for mitigating the effects of such an event. Given the capabilities and roles for responding to a radiological event extend across many agencies, a consensus of gaps and suggested development plans was a major goal of this evaluation and road-mapping effort. The working group consisted of experts representing the Departments of Homeland Security, Health and Human Services (Centers for Disease Control and the National Institutes of Health), Food and Drug Administration, Department of Defense and the Department of Energy's National Laboratories (see appendix A for participants). The specific goals of this Technology Assessment and Roadmap were to: (1) Describe the general context for deployment of emergency radiation dose assessment tools following terrorist use of a radiological or nuclear device; (2) Assess current and emerging dose assessment technologies; and (3) Put forward a consensus high-level technology roadmap for interagency research and development in this area. This report provides a summary of the consensus of needs, gaps and recommendations for a research program in the area of radiation dosimetry for early response, followed by a summary of the technologies available and on the near-term horizon. We then present a roadmap for a research program to bring present and emerging near-term technologies to bear on the gaps in radiation dose assessment and triage. Finally we present detailed supporting discussion on the nature of the threats we considered, the status of

20 Years of Technology and Language Assessment in "Language Learning & Technology"

Science.gov (United States)

Chapelle, Carol A.; Voss, Erik

2016-01-01

This review article provides an analysis of the research from the last two decades on the theme of technology and second language assessment. Based on an examination of the assessment scholarship published in "Language Learning & Technology" since its launch in 1997, we analyzed the review articles, research articles, book reviews,…

Social Shaping in Danish Technology Assessment

DEFF Research Database (Denmark)

Hansen, Anne Grethe; Clausen, Christian

2003-01-01

The term ‘social shaping of technology’ has been used broadly as a response to techno-economic deterministic understandings of the relations between technology and society. Social shaping has brought together analysts from different backgrounds who share a common interest in the role of social an...... in these projects contributed to new insights into the processes of technological change and thus to policy formulation. The social shaping perspective and technology assessment experiences are suggested as important guides to future technology strategies....... and political action for technology change. The authors of this article suggest that the social shaping perspective draws on lessons from technology assessments of earlier decades, lessons about the role of technology debate, participation and democratic control. We suggest that these are important......The term ‘social shaping of technology’ has been used broadly as a response to techno-economic deterministic understandings of the relations between technology and society. Social shaping has brought together analysts from different backgrounds who share a common interest in the role of social...

Strategic Framework for Implementing the Potential of Import Substitution on the Example of Railway Engineering

Directory of Open Access Journals (Sweden)

Yuliya Georgievna Lavrikova

2015-07-01

Full Text Available At present, Russia’s economy is dependent on import in some of its strategically important sectors. The recent economic and political developments such as the aggravation of geopolitical situation and termination of economic partnership between Russia and a number of countries and entities, and also the Government’s policy that aims to reduce import dependence determine the need to expand the interaction between domestic producers and the need to use domestic resources, materials and equipment in economic activities. Import substitution in Russia can become a driving force of its industrial growth. The paper presents different interpretations of the term “import substitution” contained in several publications of recent years; it also reveals a common approach of the authors to this problem. The article summarizes existing proposals on priority areas of import substitution such as the shift towards import-substituting production and technology in strategically important industries. Mechanical engineering is seen as a most important industry in this respect. Russia’s machine-building complex is a highly diversified industry, therefore the policy of import substitution implies that it will be implemented efficiently in various sectors of mechanical engineering on the basis of the differentiated approach, with regard to industry and sectoral specifics. The article considers a strategic framework for the implementation of the import substitution potential on the example of railway engineering. The authors reveal trends in the development of the internal market of railway engineering products; they determine the degree of import dependence for individual sectors of the industry on the basis of statistical data. The article substantiates priorities and possibilities of import substitution in different sectors, and in high-tech sectors of railway engineering. The authors point out a goal of import substitution in these sectors, the goal is to

Technology needs assessment for DOE environmental restoration programs

International Nuclear Information System (INIS)

Duray, J.R.; Carlson, T.J.; Carpenter, C.E.; Cummins, L.E.; Daub, G.J.

1992-01-01

The 'Technology Needs Assessment Final Report' describes current and planned environmental restoration activity, identifies technologies intended to be used or under consideration, and ranks technology deficiencies in the U.S. Department of Energy's environmental restoration program. Included in the ranking are treatment technologies, characterization technologies, and non-technology issues that affect environmental restoration. Data used for the assessment was gathered during interviews in the spring of 1991 with DOE site personnel responsible for the environmental restoration work. (author)

Development of Integrated Assessment Technology of Risk and Performance

International Nuclear Information System (INIS)

Yang, Jun Eon; Kang, Dae Il; Kang, Hyun Gook

2010-04-01

The main idea and contents are summarized as below 1) Development of new risk/performance assessment system innovating old labor-intensive risk assessment structure - New consolidated risk assessment technology from various hazard(flood, fire, seismic in NPP) - BOP model development for performance monitoring - Consolidated risk/performance management system for consistency and efficiency of NPP 2) Resolution technology for pending issues in PSA - Base technology for PSA of digital I and C system - Base technology for seismic PSA reflecting domestic seismic characteristics and aging effect - Uncertainty reduction technology for level 2 PSA and best estimation of containment failure frequency 3) Next generation risk/performance assessment technology - Human-induced error reduction technology for efficient operation of a NPP

Technical and Technological Skills Assessment in Laparoscopic Surgery

Science.gov (United States)

Chang, Avril; Vincent, Charles

2006-01-01

Objectives: Surgical appraisal and revalidation are key components of good surgical practice and training. Assessing technical skills in a structured manner is still not widely used. Laparoscopic surgery also requires the surgeon to be competent in technological aspects of the operation. Methods: Checklists for generic, specific technical, and technological skills for laparoscopic cholecystectomies were constructed. Two surgeons with >12 years postgraduate surgical experience assessed each operation blindly and independently on DVD. The technological skills were assessed in the operating room. Results: One hundred operations were analyzed. Eight trainees and 10 consultant surgeons were recruited. No adverse events occurred due to technical or technological skills. Mean interrater reliability was kappa=0.88, P=technical and technological skills between trainee and consultant surgeons were significant, Mann-Whitney P=technical and technological skills can be measured to assess performance of laparoscopic surgeons. This technical and technological assessment tool for laparoscopic surgery seems to have face, content, concurrent, and construct validities and could be modified and applied to any laparoscopic operation. The tool has the possibility of being used in surgical training and appraisal. We aim to modify and apply this tool to advanced laparoscopic operations. PMID:17212881

Legitimation problems of participatory processes in technology assessment and technology policy.

Science.gov (United States)

Saretzki, Thomas

2012-11-01

Since James Carroll (1971) made a strong case for "participatory technology", scientists, engineers, policy-makers and the public at large have seen quite a number of different approaches to design and implement participatory processes in technology assessment and technology policy. As these participatory experiments and practices spread over the last two decades, one could easily get the impression that participation turned from a theoretical normative claim to a working practice that goes without saying. Looking beyond the well-known forerunners and considering the ambivalent experiences that have been made under different conditions in various places, however, the "if" and "how" of participation are still contested issues when questions of technology are on the agenda. Legitimation problems indicate that attempts to justify participation in a given case have not been entirely successful in the eyes of relevant groups among the sponsors, participants, organizers or observers. Legitimation problems of participatory processes in technology assessment and technology policy vary considerably, and they do so not only with the two domains and the ways of their interrelation or the specific features of the participatory processes. If we ask whether or not participation is seen as problematic in technology assessment and technology policy-making and in what sense it is being evaluated as problematic, then we find that the answer depends also on the approaches and criteria that have been used to legitimize or delegitimize the call for a specific design of participation.

The Past and the Future of Constructive Technology Assessment

NARCIS (Netherlands)

Schot, Johan; Rip, Arie

1997-01-01

Constructive technology assessment (CTA) is a member of the family of technology assessment approaches. developed in particular in the Netherlands and Denmark. CTA shifts the focus away from assessing impacts of new technologies to broadening design, development, and implementation processes.

Communication Media and Educational Technology: An Overview and Assessment with Reference to Communication Satellites.

Science.gov (United States)

Ohlman, Herbert

In this survey and analysis of the present state and future trends of communication media and educational technology, particular emphasis is placed on the potential uses of communication satellites and the substitution of electronic transmission for physical distribution of educational materials. The author analyzes in detail the characteristics…

Assessing environmental impacts of storage technologies and competing options for balancing demand and supply in 2050

Energy Technology Data Exchange (ETDEWEB)

Droste-Franke, Bert [Europaeische Akademie Bad Neuenahr-Ahrweiler GmbH, Bad Neuenahr-Ahrweiler (Germany)

2012-07-01

The major aim of using renewable energies for electricity production is to realise a sustainable and environmental friendly energy system which can be operated viably in the long term. One major indicator to reach this aim is the overall emission of CO2 resulting from the use of a certain technology. However, further environmental aspects have to be taken into account for an adequate evaluation of technologies. With respect to preserving the environmental basis for future generations several environmental pressures have to be considered which can either lead to small and substitutable, marginal environmental damages or to environmental impacts which contribute to burdens which could become critical, i.e., jeopardising important environmental functions. Thus, it should be accounted for the societal acceptability of their (potential) environmental impacts. The analysis presented here deals with the assessment of environmental effects of both types, marginal and potentially critical, for current and advanced technologies which can be used for balancing fluctuations in the electricity production from renewable sources in an economic environment of 2050. The basic results used were derived in a study carried out by the Europaeische Akademie GmbH (Droste-Franke et al. 2012).

Protein substitute for children and adults with phenylketonuria.

Science.gov (United States)

Yi, Sarah H L; Singh, Rani H

2015-02-27

Phenylketonuria is an inherited metabolic disorder characterised by an absence or deficiency of the enzyme phenylalanine hydroxylase. The aim of treatment is to lower blood phenylalanine concentrations to the recommended therapeutic range to prevent developmental delay and support normal growth. Current treatment consists of a low-phenylalanine diet in combination with a protein substitute which is free from or low in phenylalanine. Guidance regarding the use, dosage, and distribution of dosage of the protein substitute over a 24-hour period is unclear, and there is variation in recommendations among treatment centres. This is an update of a Cochrane review first published in 2005, and previously updated in 2008. To assess the benefits and adverse effects of protein substitute, its dosage, and distribution of dose in children and adults with phenylketonuria who are adhering to a low-phenylalanine diet. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register which consists of references identified from comprehensive electronic database searches and hand searches of relevant journals and abstract books of conference proceedings. We also contacted manufacturers of the phenylalanine-free and low-phenylalanine protein substitutes for any data from published and unpublished randomised controlled trials.Date of the most recent search of the Group's Inborn Errors of Metabolism Trials Register: 03 April 2014. All randomised or quasi-randomised controlled trials comparing: any dose of protein substitute with no protein substitute; an alternative dosage; or the same dose, but given as frequent small doses throughout the day compared with the same total daily dose given as larger boluses less frequently. Both authors independently extracted data and assessed trial quality. Three trials (69 participants) are included in this review. One trial investigated the use of protein substitute in 16 participants, while a further two trials investigated the

Technology assessments in transportation: survey of recent literature

Energy Technology Data Exchange (ETDEWEB)

LaBelle, S.J.

1980-03-01

A survey and an evaluation of recent studies of transportation systems done in a technology-assessment framework were undertaken as the basis for a detailed statement of work for a US Department of Energy technology assessment of transportation energy-conservation strategies. Several bibliographies were searched and numerous professionals in the field of technology assessment were contacted regarding current work. Detailed abstracts were prepared for studies judged to be sufficiently broad in coverage of impacts assessed, yet detailed in coverage of all or part of the nation's transportation systems. Some studies were rich in data but not comprehensive in their analytical approach; brief abstracts were prepared for these. An explanation of the criteria used to screen the studies, as well as abstracts of 37 reports, are provided in this compendium of transportation-technology-assessment literature.

Substituting oil by electric power

International Nuclear Information System (INIS)

Lichtenberg, H.

1981-01-01

Parting from the development of primary energy use the author refers to the latest investigations and results presented on the 1980 World Energy Conference and with special regard to oil points out the threatening exhaustion of fossil energy resources. Maintaining the economic structure of the Federal Republic of Germany implies an orientation away from oil. Due to its flexible application technology and quasi-inexhaustible energy resources electric power may substantially contribute to oil substitution which as a matter of fact is of particular interest in connection with the heat market. Coal alone cannot substitute both oil and nuclear energy. Thus, the above postulates the use of the latter. Leaving nuclear energy inactive today will effect an increase in the demand for oil the negative consequences of which would weight heavily upon the anyhow unbalanced import/export ratio of the Federal Republic of Germany. (orig.) [de

LABOR SUBSTITUTABILITY IN LABOR INTENSIVE AGRICULTURE AND TECHNOLOGICAL CHANGE IN THE PRESENCE OF FOREIGN LABOR

OpenAIRE

Napasintuwong, Orachos; Emerson, Robert D.

2004-01-01

The Morishima elasticity of substitution (MES) is estimated to address factor substitutability in Florida agriculture during 1960-1999. By adopting a profit maximization model of induced innovation theory, the MES's between hired and self-employed labor and the MES's between labor and capital provide implications for future immigration policies.

Spent Nuclear Fuel Alternative Technology Risk Assessment

Energy Technology Data Exchange (ETDEWEB)

Perella, V.F.

1999-11-29

A Research Reactor Spent Nuclear Fuel Task Team (RRTT) was chartered by the Department of Energy (DOE) Office of Spent Fuel Management with the responsibility to recommend a course of action leading to a final technology selection for the interim management and ultimate disposition of the foreign and domestic aluminum-based research reactor spent nuclear fuel (SNF) under DOE''s jurisdiction. The RRTT evaluated eleven potential SNF management technologies and recommended that two technologies, direct co-disposal and an isotopic dilution alternative, either press and dilute or melt and dilute, be developed in parallel. Based upon that recommendation, the Westinghouse Savannah River Company (WSRC) organized the SNF Alternative Technology Program to further develop the direct co-disposal and melt and dilute technologies and provide a WSRC recommendation to DOE for a preferred SNF alternative management technology. A technology risk assessment was conducted as a first step in this recommendation process to determine if either, or both, of the technologies posed significant risks that would make them unsuitable for further development. This report provides the results of that technology risk assessment.

Spent Nuclear Fuel Alternative Technology Risk Assessment

International Nuclear Information System (INIS)

Perella, V.F.

1999-01-01

A Research Reactor Spent Nuclear Fuel Task Team (RRTT) was chartered by the Department of Energy (DOE) Office of Spent Fuel Management with the responsibility to recommend a course of action leading to a final technology selection for the interim management and ultimate disposition of the foreign and domestic aluminum-based research reactor spent nuclear fuel (SNF) under DOE''s jurisdiction. The RRTT evaluated eleven potential SNF management technologies and recommended that two technologies, direct co-disposal and an isotopic dilution alternative, either press and dilute or melt and dilute, be developed in parallel. Based upon that recommendation, the Westinghouse Savannah River Company (WSRC) organized the SNF Alternative Technology Program to further develop the direct co-disposal and melt and dilute technologies and provide a WSRC recommendation to DOE for a preferred SNF alternative management technology. A technology risk assessment was conducted as a first step in this recommendation process to determine if either, or both, of the technologies posed significant risks that would make them unsuitable for further development. This report provides the results of that technology risk assessment

Space-reactor electric systems: subsystem technology assessment

International Nuclear Information System (INIS)

Anderson, R.V.; Bost, D.; Determan, W.R.

1983-01-01

This report documents the subsystem technology assessment. For the purpose of this report, five subsystems were defined for a space reactor electric system, and the report is organized around these subsystems: reactor; shielding; primary heat transport; power conversion and processing; and heat rejection. The purpose of the assessment was to determine the current technology status and the technology potentials for different types of the five subsystems. The cost and schedule needed to develop these potentials were estimated, and sets of development-compatible subsystems were identified

High Technology Development and Creation of Experimental Industrial Area of High-Performance Precision Diamond Dress Tool Production for Engineering Needs and Import Substitution in Ukraine

Directory of Open Access Journals (Sweden)

N. Novikov

2013-09-01

Full Text Available Manufacturing design of high-precision diamond tool for special applications carried out at V. M Bakul Institute for Superhard Materials of NAS of Ukraine is described. Presented developments open up scientific and technological capabilities of special dress diamond tool production for mechanical engineering and substitution of imported tools at Ukrainian enterprises by home-produced.

True North: Building Imaginary Worlds with the Revised Canadian (CADTH Guidelines for Health Technology Assessment

Directory of Open Access Journals (Sweden)

Paul C Langley

2017-05-01

Full Text Available In March 2017 the Canadian Agency for Drugs and Technologies in Health (CADTH released the 4th edition of their Guidelines for the Economic Evaluation of Health Technologies: Canada. These guidelines, which were first published and revised for a 3rd edition in 2006 are intended to help decision makers, health systems leaders and policy makers make well-informed decisions. They are designed, apparently, to support best practice in conducting health technology assessments in Canada. The purpose of this commentary is to consider whether or not the evidence standards proposed and the consequent modeled claims for economic effectiveness meet the standards of normal science: are the CADTH standards capable of generating claims for competing products that are credible, evaluable and replicable? The review argues that the standards proposed by CADTH do not meet the standards expected in normal science. Technical sophistication in building reference case imaginary worlds is not a substitute for claims that are experimentally evaluable or capable of assessment through systematic observation. There is no way of judging whether imaginary claims are right or even if they are wrong. CADTH is not alone in setting standards that fail to meet the standards of normal science. Recent commentaries on formulary submission guidelines in a number of other countries, to include Ireland, the Netherlands, France, Australia, the UK and New Zealand conclude that they are subject to the same criticism. If the CADTH guidelines were never intended to support feedback to health system decision makers, then this should be made clear. If not, then consideration should be given to withdrawing the guidelines to ensure they conform to these standards. Hopefully, future versions of the CADTH guidelines will address this issue and focus on a rigorous research program of claims assessment and feedback and not the building of imaginary worlds.   Type:  Commentary

The Role of Perceived Substitution and Individual Culture in the Adoption of Electronic Newspapers in Scandinavia

DEFF Research Database (Denmark)

Pogrebnyakov, Nicolai; Buchmann, Mikael

2014-01-01

Introduction:This paper explores the factors behind the adoption of electronic newspapers. Adoption is hypothesized to be driven by attributes of the electronic newspaper artefact (expressed by perceived substitution) and individual cultural characteristics of potential adopters. Perceived substi...... technology over another may lead to adoption, as well as to studies that investigate the role of individual cultural characteristics in the adoption of information and communication technologies....... was used to test hypotheses. Results: The results indicate that perceived substitution explains the adoption of electronic newspapers well, while most cultural factors did not show a significant effect on adoption. Conclusion: These results add to research on how perceived substitutive functionality of one...

Resources, recycle, and substitution

International Nuclear Information System (INIS)

Wymer, R.G.

A two-fold strategy appears necessary to ensure that the resource needs of the developed and developing nations are met. First, recycle and substitution must be encouraged in those instances where they do find application. Although these measures have limited applicability, they may be of vital importance in those instances where they do apply; in any event, they buy time. Second, practical and economical technologies must be developed to exploit the lower-grade and marginal ores and the oftentimes abundant but highly refractory ores, as well as to greatly increase the recovery of secondary elements present in the ores - elements whose form and amounts in the ores make them economically unrecoverable by themselves, but which are economically recoverable as by-products. It is often the case that if these elements are not recovered during the initial mining and milling operations, they are rendered unrecoverable, in a practical sense, forever. Furthermore, they may even become environmental pollutants. Specific examples of recovery from refractory ores, by-product recovery, and recycle are given. Also, some suggestions of substitutes for important resources are tabulated

Fiscal 1975 Sunshine Project research report. Technology assessment on hydrogen energy technology. Part 2; 1975 nendo suiso energy gijutsu no technology assessment seika hokokuksho. 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1976-03-31

This research assesses the impact of development of practical hydrogen energy technology on the economy, society and environment in Japan, and proposes some effective countermeasures, the required technical development target and a promising promotion system. The example of technology assessment assuming practical technology several tens years after is hardly found. Hydrogen energy technology is in the first stage among (1) initial planning stage, (2) technical research and development stage, (3) practical technology stage and (4) service operation stage. In the first fiscal year, as the first stage of determination of the communication route between society and technology, study was made on the concrete system image of practical technology. In this fiscal year, study was made entirely on preparation of the scenario for imaging the future economy and society concretely, modifying the planning of the hydrogen energy system. Through comparison of the scenario and system, the meaning and problem of the hydrogen energy technology were clarified. (NEDO)

Predicting technology operational availability using technical maturity assessment

International Nuclear Information System (INIS)

Kenley, C.R.; Creque, T.R.

1998-01-01

A technical maturity assessment method was performed by systems engineers in collaboration with an advisory panel composed of team members from different Department of Energy sites and from different engineering and science disciplines. Various stabilization technologies were assessed annually as to their relative maturity and availability for use in stabilizing nuclear materials. After three years of assessments, several of the technologies are now components of operational systems. A regression analysis of the historical assessments was performed, and it was concluded that the numerical technical maturity score produced by a team of experts can provide a powerful predictor of the time remaining until the operational application of technologies

Conceptual approach to the development of an active process of import substitution

Directory of Open Access Journals (Sweden)

Yu. A. Salikov

2018-01-01

Full Text Available In the current political and economic situation, the process of import substitution is of particular importance. Modern processes of social globalization involve the expansion of cooperation and integration of all levels and types of social production. However, there is a risk of increasing risks in the areas of economic and defense security, openness of new technologies, consumer (food and commodity dependence, that is, increasing the risk of loss of stability of the socio-economic system. It is obvious that the main strategic objectives for socio-economic systems are different for each hierarchical level. At the macroeconomic level, these tasks are related not only to the formation of a system of priorities and incentives for the reorientation of the national reproductive complex to the production of import-substituting products, but also to the development of an institutional framework for initiating and launching import-substitution processes.. Import substitution is an active process of replacing imported goods with domestic analogues. It is important to note that for the Russian Federation import substitution is forced, because the beginning of the policy of substitution of foreign goods for goods produced domestically against Russia was introduced a number of trade and economic sanctions imposed by the countries of Europe and the United States. In addition, it should be emphasized that the process of import substitution in the domestic economy should a priori have realistic and objectively marked borders, as the the task of ensuring that excessive (as a limit – one hundred percent of replacement itself is not only achievable in principle, but requiring undue effort and material costs, can cause considerable damage to the national economy. The analysis of the theories of foreign direct investment. The scheme of construction of production on the basis of active import substitution was built. Thus, it is necessary to note the importance of

The contribution of health technology assessment, health needs assessment, and health impact assessment to the assessment and translation of technologies in the field of public health genomics.

Science.gov (United States)

Rosenkötter, N; Vondeling, H; Blancquaert, I; Mekel, O C L; Kristensen, F B; Brand, A

2011-01-01

The European Union has named genomics as one of the promising research fields for the development of new health technologies. Major concerns with regard to these fields are, on the one hand, the rather slow and limited translation of new knowledge and, on the other hand, missing insights into the impact on public health and health care practice of those technologies that are actually introduced. This paper aims to give an overview of the major assessment instruments in public health [health technology assessment (HTA), health needs assessment (HNA) and health impact assessment (HIA)] which could contribute to the systematic translation and assessment of genomic health applications by focussing at population level and on public health policy making. It is shown to what extent HTA, HNA and HIA contribute to translational research by using the continuum of translational research (T1-T4) in genomic medicine as an analytic framework. The selected assessment methodologies predominantly cover 2 to 4 phases within the T1-T4 system. HTA delivers the most complete set of methodologies when assessing health applications. HNA can be used to prioritize areas where genomic health applications are needed or to identify infrastructural needs. HIA delivers information on the impact of technologies in a wider scope and promotes informed decision making. HTA, HNA and HIA provide a partly overlapping and partly unique set of methodologies and infrastructure for the translation and assessment of genomic health applications. They are broad in scope and go beyond the continuum of T1-T4 translational research regarding policy translation. Copyright © 2010 S. Karger AG, Basel.

Simple, heart-smart substitutions

Science.gov (United States)

Coronary artery disease - heart smart substitutions; Atherosclerosis - heart smart substitutions; Cholesterol - heart smart substitutions; Coronary heart disease - heart smart substitutions; Healthy diet - heart ...

The Contribution of Health Technology Assessment, Health Needs Assessment, and Health Impact Assessment to the Assessment and Translation of Technologies in the Field of Public Health Genomics

DEFF Research Database (Denmark)

Rosenkotter, N.; Vondeling, H.; Blancquaert, I.

2011-01-01

contribute to the systematic translation and assessment of genomic health applications by focussing at population level and on public health policy making. It is shown to what extent HTA, HNA and HIA contribute to translational research by using the continuum of translational research (T1-T4) in genomic...... into the impact on public health and health care practice of those technologies that are actually introduced. This paper aims to give an overview of the major assessment instruments in public health [ health technology assessment (HTA), health needs assessment (HNA) and health impact assessment (HIA)] which could...... medicine as an analytic framework. The selected assessment methodologies predominantly cover 2 to 4 phases within the T1-T4 system. HTA delivers the most complete set of methodologies when assessing health applications. HNA can be used to prioritize areas where genomic health applications are needed...

Technology assessment and social science research on technology

International Nuclear Information System (INIS)

Thienen, V. von

1983-01-01

In a first step this bibliography wants to overcome the want of systematic scientific data compilations and evaluations of experiences in studies on technology assessment. It concentrates on the social and political aspects of the development of technologies and the decision on their utilization by presenting titles which have been published in English- and German-speaking countries in the past decade. The bibliography is divided into various chapters and subchapters. The index part contains authors' indexes and publishers' indexes, subject indexes, other bibliographies and selected periodicals. (orig.) With 1647 refs [de

Technologies for Language Assessment.

Science.gov (United States)

Burstein, Jill; And Others

1996-01-01

Reviews current and developing technology uses that are relevant to language assessment and discusses examples of recent linguistic applications from the laboratory at the Educational Testing Service. The processes of language test development are described and the functions they serve from the perspective of a large testing organization are…

IMPORT SUBSTITUTION POLICY UNDER ANTI-RUSSIAN SANCTIONS: STATE AND PROSPECTS

Directory of Open Access Journals (Sweden)

Elena Vyacheslavovna Galkina

2016-02-01

Full Text Available In the context of Western sanctions caused by the events in Ukraine, a sharp drop in oil prices and other commodity prices, Russia is in a difficult political and economic situation. In these conditions, pressing was the question of replacement technologies and products imported from abroad, especially from the European Union, acceding to the anti-Russian sanctions, initiated by the United States. The political leadership of the Russian Federation have repeatedly raised the issue of import substitution, and only the events of recent years have allowed to translate public policy in this area to the actual implementation of programs developed its own production of goods and technology that were previously imported from abroad.Objective: To analyze the current political developments in the modern world and show the pros and cons of the policy of import substitution in Russia in terms of anti-Russian sanctions.Method and methodology of work: Institutional and neo-institutional paradigm, systematic approach.Results: The authors note that the import substitution program in import substitution, in spite of the marked complexity, have a good chance of success, and this is the key to low-cost raw materials, relatively cheap labor, cheap energy sources – natural gas and electricity, as well as carried out in 2014–2015 devaluation of the ruble, which significantly reduce the cost of the potential costs of enterprises.Application of the results: political science and practice, economic policy.

Swedish Technology Teachers' Views on Assessing Student Understandings of Technological Systems

Science.gov (United States)

Schooner, Patrick; Klasander, Claes; Hallström, Jonas

2018-01-01

Technology education is a new school subject in comparison with other subjects within the Swedish compulsory school system. Research in technology education shows that technology teachers lack experience of and support for assessment in comparison with the long-term experiences that other teachers use in their subjects. This becomes especially…

Sustainability assessment of advanced wastewater treatment technologies

DEFF Research Database (Denmark)

Høibye, Linda; Clauson-Kaas, Jes; Wenzel, Henrik

2007-01-01

, which includes technical, economic and environmental aspects. The technical and economic assessment is performed on 5 advanced treatment technologies: sand filtration, ozone treatment, UV exclusively for disinfection of pathogenic microorganisms, Membrane Bioreactor (MBR), and UV in combination......As a consequence of the EU Water Framwork Directive, more focus is now on discharges of hazardous substances from wastewater treatment plants and sewers. Thus, many municipalities in Denmark may have to adopt to future advenced treatment technologies. This paper describes a holistic assessment...... with advanced oxidation. The technical assessment is based on 12 hazardous substances comprising heavy metals, organic pollutants, endocrine disruptors as well as pathogenic microorganisms. The environmental assessment is performed by life cycle assessment (LCA) comprising 9 of the specific hazardous substances...

Sustainability assessment of advanced wastewater treatment technologies

DEFF Research Database (Denmark)

Høibye, Linda; Clauson-Kaas, Jes; Wenzel, Henrik

2008-01-01

, which includes technical, economical and environmental aspects. The technical and economical assessment is performed on 5 advanced treatment technologies: sand filtration, ozone treatment, UV exclusively for disinfection of pathogenic microorganisms, membrane bioreactor (MBR) and UV in combination......As a consequence of the EU Water Framework Directive more focus is now on discharges of hazardous substances from wastewater treatment plants and sewers. Thus, many municipalities in Denmark may have to adopt to future advanced treatment technologies. This paper describes a holistic assessment...... with advanced oxidation. The technical assessment is based on 12 hazardous substances comprising heavy metals, organic pollutants, endocrine disruptors as well as pathogenic microorganisms. The environmental assessment is performed by life cycle assessment (LCA) comprising 9 of the specific hazardous substances...

Critical Metals in Strategic Energy Technologies. Assessing Rare Metals as Supply-Chain Bottlenecks in Low-Carbon Energy Technologies

International Nuclear Information System (INIS)

Moss, R.L.; Tzimas, E.; Kara, H.; Willis, P.; Kooroshy, J.

2011-11-01

Due to the rapid growth in demand for certain materials, compounded by political risks associated with the geographical concentration of the supply of them, a shortage of these materials could be a potential bottleneck to the deployment of low-carbon energy technologies. In order to assess whether such shortages could jeopardise the objectives of the EU's Strategic Energy Technology Plan (SET-Plan), an improved understanding of these risks is vital. In particular, this report examines the use of metals in the six low-carbon energy technologies of SET-Plan, namely: nuclear, solar, wind, bioenergy, carbon capture and storage (CCS) and electricity grids. The study looks at the average annual demand for each metal for the deployment of the technologies in Europe between 2020 and 2030. The demand of each metal is compared to the respective global production volume in 2010. This ratio (expressed as a percentage) allows comparing the relative stress that the deployment of the six technologies in Europe is expected to create on the global supplies for these different metals. The study identifies 14 metals for which the deployment of the six technologies will require 1% or more (and in some cases, much more) of current world supply per annum between 2020 and 2030. These 14 metals, in order of decreasing demand, are tellurium, indium, tin, hafnium, silver, dysprosium, gallium, neodymium, cadmium, nickel, molybdenum, vanadium, niobium and selenium. The metals are examined further in terms of the risks of meeting the anticipated demand by analysing in detail the likelihood of rapid future global demand growth, limitations to expanding supply in the short to medium term, and the concentration of supply and political risks associated with key suppliers. The report pinpoints 5 of the 14 metals to be at high risk, namely: the rare earth metals neodymium and dysprosium, and the by-products (from the processing of other metals) indium, tellurium and gallium. The report explores a

Improving tag/seal technologies: the vulnerability assessment component

International Nuclear Information System (INIS)

Jones, J.L.

1996-01-01

The Department of Energy (DOE), specifically the Office of Nonproliferation and National Security, has sponsored the development of numerous tag and seal technologies for high-security/high-valued applications. One important component in this technology development effort has been the continuous integration of vulnerability assessments. The Idaho National Engineering Laboratory (INEL) has been the lead laboratory for vulnerability assessments of fiber-optic-based tag/seal technologies. This paper presents a brief historical overview and the current status of the DOE high-security tag/seal development program and discusses INEL's adversarial role and assessment philosophy. Verification testing criteria used to define ''successful'' tampering attempts/attacks are discussed. Finally, the advantages of integrating a vulnerability assessment into the development of commercial security tag/seals are presented

Statistical assessment of the learning curves of health technologies.

Science.gov (United States)

Ramsay, C R; Grant, A M; Wallace, S A; Garthwaite, P H; Monk, A F; Russell, I T

2001-01-01

(1) To describe systematically studies that directly assessed the learning curve effect of health technologies. (2) Systematically to identify 'novel' statistical techniques applied to learning curve data in other fields, such as psychology and manufacturing. (3) To test these statistical techniques in data sets from studies of varying designs to assess health technologies in which learning curve effects are known to exist. METHODS - STUDY SELECTION (HEALTH TECHNOLOGY ASSESSMENT LITERATURE REVIEW): For a study to be included, it had to include a formal analysis of the learning curve of a health technology using a graphical, tabular or statistical technique. METHODS - STUDY SELECTION (NON-HEALTH TECHNOLOGY ASSESSMENT LITERATURE SEARCH): For a study to be included, it had to include a formal assessment of a learning curve using a statistical technique that had not been identified in the previous search. METHODS - DATA SOURCES: Six clinical and 16 non-clinical biomedical databases were searched. A limited amount of handsearching and scanning of reference lists was also undertaken. METHODS - DATA EXTRACTION (HEALTH TECHNOLOGY ASSESSMENT LITERATURE REVIEW): A number of study characteristics were abstracted from the papers such as study design, study size, number of operators and the statistical method used. METHODS - DATA EXTRACTION (NON-HEALTH TECHNOLOGY ASSESSMENT LITERATURE SEARCH): The new statistical techniques identified were categorised into four subgroups of increasing complexity: exploratory data analysis; simple series data analysis; complex data structure analysis, generic techniques. METHODS - TESTING OF STATISTICAL METHODS: Some of the statistical methods identified in the systematic searches for single (simple) operator series data and for multiple (complex) operator series data were illustrated and explored using three data sets. The first was a case series of 190 consecutive laparoscopic fundoplication procedures performed by a single surgeon; the second

The SMART Platform: early experience enabling substitutable applications for electronic health records

Science.gov (United States)

Mandel, Joshua C; Murphy, Shawn N; Bernstam, Elmer Victor; Ramoni, Rachel L; Kreda, David A; McCoy, J Michael; Adida, Ben; Kohane, Isaac S

2012-01-01

Objective The Substitutable Medical Applications, Reusable Technologies (SMART) Platforms project seeks to develop a health information technology platform with substitutable applications (apps) constructed around core services. The authors believe this is a promising approach to driving down healthcare costs, supporting standards evolution, accommodating differences in care workflow, fostering competition in the market, and accelerating innovation. Materials and methods The Office of the National Coordinator for Health Information Technology, through the Strategic Health IT Advanced Research Projects (SHARP) Program, funds the project. The SMART team has focused on enabling the property of substitutability through an app programming interface leveraging web standards, presenting predictable data payloads, and abstracting away many details of enterprise health information technology systems. Containers—health information technology systems, such as electronic health records (EHR), personally controlled health records, and health information exchanges that use the SMART app programming interface or a portion of it—marshal data sources and present data simply, reliably, and consistently to apps. Results The SMART team has completed the first phase of the project (a) defining an app programming interface, (b) developing containers, and (c) producing a set of charter apps that showcase the system capabilities. A focal point of this phase was the SMART Apps Challenge, publicized by the White House, using http://www.challenge.gov website, and generating 15 app submissions with diverse functionality. Conclusion Key strategic decisions must be made about the most effective market for further disseminating SMART: existing market-leading EHR vendors, new entrants into the EHR market, or other stakeholders such as health information exchanges. PMID:22427539

Sustaining Innovation: Developing an Instructional Technology Assessment Process

Science.gov (United States)

Carmo, Monica Cristina

2013-01-01

This case study developed an instructional technology assessment process for the Gevirtz Graduate School of Education (GGSE). The theoretical framework of Adelman and Taylor (2001) guided the development of this instructional technology assessment process and the tools to aid in its facilitation. GGSE faculty, staff, and graduate students…

Genotoxicity risk assessment of diversely substituted quinolines using the SOS chromotest.

Science.gov (United States)

Duran, Leidy Tatiana Díaz; Rincón, Nathalia Olivar; Galvis, Carlos Eduardo Puerto; Kouznetsov, Vladimir V; Lorenzo, Jorge Luis Fuentes

2015-03-01

Quinolines are aromatic nitrogen compounds with wide therapeutic potential to treat parasitic and microbial diseases. In this study, the genotoxicity of quinoline, 4-methylquinoline, 4-nitroquinoline-1-oxide (4-NQO), and diversely functionalized quinoline derivatives and the influence of the substituents (functional groups and/or atoms) on their genotoxicity were tested using the SOS chromotest. Quinoline derivatives that induce genotoxicity by the formation of an enamine epoxide structure did not induce the SOS response in Escherichia coli PQ37 cells, with the exception of 4-methylquinoline that was weakly genotoxic. The chemical nature of the substitution (C-5 to C-8: hydroxyl, nitro, methyl, isopropyl, chlorine, fluorine, and iodine atoms; C-2: phenyl and 3,4-methylenedioxyphenyl rings) of quinoline skeleton did not significantly modify compound genotoxicities; however, C-2 substitution with α-, β-, or γ-pyridinyl groups removed 4-methylquinoline genotoxicity. On the other hand, 4-NQO derivatives whose genotoxic mechanism involves reduction of the C-4 nitro group were strong inducers of the SOS response. Methyl and nitrophenyl substituents at C-2 of 4-NQO core affected the genotoxic potency of this molecule. The relevance of these results is discussed in relation to the potential use of the substituted quinolines. The work showed the sensitivity of SOS chromotest for studying structure-genotoxicity relationships and bioassay-guided quinoline synthesis. © 2013 Wiley Periodicals, Inc.

Estimates of inter-fuel substitution possibilities in Chinese chemical industry

International Nuclear Information System (INIS)

Lin, Boqiang; Wesseh, Presley K.

2013-01-01

The chemical sector is a key driver of China's remarkable growth record and accounts for about 10% of the country's GDP. This has made the industry energy-intensive and consequently a major contributor to greenhouse gas emissions (GHG) and other pollutants. This study has attempted to investigate the potential for inter-fuel substitution between coal, oil, natural gas and electricity in Chinese chemical sector by employing a translog production and cost function. Ridge regression procedure was adopted to estimate the parameters of the function. Estimation results show that all energy inputs are substitutes. In addition, the study produces evidence that the significant role of coal in the Chinese chemical fuel mix converges over time, albeit slowly. These results suggest that price-based policies, coupled with capital subsidy programs can be adopted to redirect technology use towards cleaner energy sources like electricity and natural gas; hence, retaining the ability to fuel the chemical sector, while also mitigating GHG emissions. Notwithstanding, one must understand that the extent to which substituting electricity for coal will be effective depends on the extent to which coal or oil is used in generating electricity. The findings of this study provide general insights and underscore the importance of Chinese government policies that focus on installed capacity of renewable electricity, energy intensity targets as well as merger of enterprises. - Highlights: • Potential for inter-fuel substitution in Chinese chemical sector is investigated. • Oil, natural gas and electricity are found to be substitutes for coal. • Coal dominance in Chinese chemical fuel mix is found to converge over time. • Price-based policies and capital-subsidies are needed to redirect technology use. • Results support policies concerning renewables, energy-intensity targets and mergers

Student Perceptions of Using Tablet Technology in Post-Secondary Classes

Science.gov (United States)

Mang, Colin F.; Wardley, Leslie J.

2013-01-01

This paper assesses students' attitudes towards using tablets, such as the Apple iPad, in university classes. Tablets are found to be a substitute for laptop computers. Students initially expressed a great deal of optimism regarding the technology, and, although their views diminished slightly as they gained experience with using a tablet,…

Guidance on the Technology Performance Level (TPL) Assessment Methodology

Energy Technology Data Exchange (ETDEWEB)

Weber, Jochem [National Renewable Energy Lab. (NREL), Golden, CO (United States); Roberts, Jesse D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Babarit, Aurelien [Ecole Centrale de Nantes (France). Lab. of Research in Hydrodynamics, Energetics and Atmospheric Environment (LHEEA); Costello, Ronan [Wave Venture, Penstraze (United Kingdom); Bull, Diana L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Neilson, Kim [Ramboll, Copenhagen (Denmark); Bittencourt, Claudio [DNV GL, London (United Kingdom); Kennedy, Ben [Wave Venture, Penstraze (United Kingdom); Malins, Robert Joseph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dykes, Katherine [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2016-09-01

This document presents the revised Technology Performance Level (TPL) assessment methodology. There are three parts to this revised methodology 1) the Stakeholder Needs and Assessment Guidance (this document), 2) the Technical Submission form, 3) the TPL scoring spreadsheet. The TPL assessment is designed to give a technology neutral or agnostic assessment of any wave energy converter technology. The focus of the TPL is on the performance of the technology in meeting the customer’s needs. The original TPL is described in [1, 2] and those references also detail the critical differences in the nature of the TPL when compared to the more widely used technology readiness level (TRL). (Wave energy TRL is described in [3]). The revised TPL is particularly intended to be useful to investors and also to assist technology developers to conduct comprehensive assessments in a way that is meaningful and attractive to investors. The revised TPL assessment methodology has been derived through a structured Systems Engineering approach. This was a formal process which involved analyzing customer and stakeholder needs through the discipline of Systems Engineering. The results of the process confirmed the high level of completeness of the original methodology presented in [1] (as used in the Wave Energy Prize judging) and now add a significantly increased level of detail in the assessment and an improved more investment focused structure. The revised TPL also incorporates the feedback of the Wave Energy Prize judges.

Pesticide Substitution: Combining Food Safety with Environmental Quality

DEFF Research Database (Denmark)

Fantke, Peter

2015-01-01

Various pesticides are authorized for use on agricultural food crops. Despite regulatory risk assessments aiming at ensuring consumer and environmental safety, pesticides contribute to human and environmental impacts. Guidance is needed to optimize pesticide use practice and minimize human...... and environmental exposure. Comparative pesticide substitution scenarios are presented to address this need. In a case study on wheat, different pesticides have been compared with respect to their substitution potential with focus on human health. Results demonstrate that health impacts can be reduced up to 99......% by defining adequate substitution scenarios. Comprehensive scenarios need to also consider worker and environmental burden, and information on crop rotation, pest pressure, environmental conditions, application costs and efficacy. Such scenarios help to increase food safety and more sustainable use...

Technology and public policy: The process of technology assessment in the federal government

Science.gov (United States)

Coates, V. T.

1975-01-01

A study was conducted to provide a descriptive and analytical review of the concept of technology assessment and the current status of its applications in the work of the federal executive agencies. The origin of the term technology assessment was examined along with a brief history of its discussion and development since 1966 and some of the factors influencing that development.

Technology assessment of in situ uranium mining

International Nuclear Information System (INIS)

Cowan, C.E.

1981-01-01

The objective of the PNL portion of the Technology Assessment project is to provide a description of the current in situ uranium mining technology; to evaluate, based on available data, the environmental impacts and, in a limited fashion, the health effects; and to explore the impediments to development and deployment of the in situ uranium mining technology

Technology assessment for Spaceship Two, space tourism, and private spaceflight

Science.gov (United States)

Hancock, Randy

A seven-step technology assessment was conducted to address questions regarding the significance and likely consequences associated with the introduction of Spaceship Two, space tourism, and private spaceflight. Impacts were assessed across four categories: the Role and Functions of Government, Private Industry Factors, Cultural and Societal Impacts, and the Time Frame in which these impacts were anticipated to occur. The technology assessment findings were compared to the results of expert interviews that addressed the sane four categories. The researcher noted that, while there was overwhelming agreement between the technology assessment's primary impacts and the expert interview responses, there were several differences. The technology assessment and interviewees agreed that the federal government would likely be both a regulator and user of private spaceflight. Both agreed that business partnerships would be key in pursuing private spaceflight. There was also consensus that, as market forces come to bear, ticket prices would drop and a larger market and broader passenger demographic would emerge. The technology assessment and experts agreed that an accident, especially one early in the industry's evolution, could be disastrous. Both agreed that private spaceflight can serve as a inspiration to students and be a positive influence in society, and both agreed that the start of passenger flights should take place in the 2010 - 2012 timeframe. Due to the potentially disastrous consequences of an accident, there was agreement between the technology assessment and experts on the value of flight and ground crew training, driven by insurance carriers and federal mandate. Most differences between the technology assessment's findings and the expert interview responses were due to omission, rather than direct disagreement. However, this was not the case in every instance. The most significant difference between the technology assessment and the experts involved the

Technology assessment and technology policy in Europe : New concepts, new goals, new infrastructures

NARCIS (Netherlands)

Smits, R.; Leyten, J.; Hertog, P. den

1995-01-01

Starting from the observation that the technological potentials are underutilized in economic and in social tems, this article raises the question of what role technology assessment (TA) can play in technology policy to address this problem. The causes of the problem of underutilization are analyzed

A Group Action Method for Construction of Strong Substitution Box

Science.gov (United States)

Jamal, Sajjad Shaukat; Shah, Tariq; Attaullah, Atta

2017-06-01

In this paper, the method to develop cryptographically strong substitution box is presented which can be used in multimedia security and data hiding techniques. The algorithm of construction depends on the action of a projective general linear group over the set of units of the finite commutative ring. The strength of substitution box and ability to create confusion is assessed with different available analyses. Moreover, the ability of resistance against malicious attacks is also evaluated. The substitution box is examined by bit independent criterion, strict avalanche criterion, nonlinearity test, linear approximation probability test and differential approximation probability test. This substitution box is equated with well-recognized substitution boxes such as AES, Gray, APA, S8, prime of residue, Xyi and Skipjack. The comparison shows encouraging results about the strength of the proposed box. The majority logic criterion is also calculated to analyze the strength and its practical implementation.

Defining the "proven technology" technical criterion in the reactor technology assessment for Malaysia's nuclear power program

Science.gov (United States)

Anuar, Nuraslinda; Kahar, Wan Shakirah Wan Abdul; Manan, Jamal Abdul Nasir Abd

2015-04-01

Developing countries that are considering the deployment of nuclear power plants (NPPs) in the near future need to perform reactor technology assessment (RTA) in order to select the most suitable reactor design. The International Atomic Energy Agency (IAEA) reported in the Common User Considerations (CUC) document that "proven technology" is one of the most important technical criteria for newcomer countries in performing the RTA. The qualitative description of five desired features for "proven technology" is relatively broad and only provides a general guideline to its characterization. This paper proposes a methodology to define the "proven technology" term according to a specific country's requirements using a three-stage evaluation process. The first evaluation stage screens the available technologies in the market against a predefined minimum Technology Readiness Level (TRL) derived as a condition based on national needs and policy objectives. The result is a list of technology options, which are then assessed in the second evaluation stage against quantitative definitions of CUC desired features for proven technology. The potential technology candidates produced from this evaluation is further narrowed down to obtain a list of proven technology candidates by assessing them against selected risk criteria and the established maximum allowable total score using a scoring matrix. The outcome of this methodology is the proven technology candidates selected using an accurate definition of "proven technology" that fulfills the policy objectives, national needs and risk, and country-specific CUC desired features of the country that performs this assessment. A simplified assessment for Malaysia is carried out to demonstrate and suggest the use of the proposed methodology. In this exercise, ABWR, AP1000, APR1400 and EPR designs assumed the top-ranks of proven technology candidates according to Malaysia's definition of "proven technology".

1,3- and 1,4-Substituted tetrazolium salts

International Nuclear Information System (INIS)

Voitekhovich, Sergei V; Gaponik, Pavel N; Ivashkevich, Oleg A

2002-01-01

The published data on the synthesis, physicochemical properties, structures and reactions of 1,3-(1,3,5)- and 1,4-(1,4,5)-substituted tetrazolium salts are systematised and generalised. Their applications as starting compounds in the preparative chemistry of heterocyclic derivatives and some other branches of science and technology are reviewed. The bibliography includes 122 references.

INFORMATION AND COMMUNICATION TECHNOLOGIES TRAINING: CRITERIA FOR INTERNAL QUALITY ASSESSMENT

Directory of Open Access Journals (Sweden)

Oleg M. Spirin

2011-02-01

Full Text Available In the article the concept of information and communication technology training is specified. It is grounded an internal criteria of information and communication technologies training quality assessment based on experience of the organization, carrying out, analysis of experimental work results on quality assessment of designing, working out, efficiency of methodical system of informatics teachers base vocational training introduction in the conditions of credit-modular technology. Indicators and approaches of their assessment to define the criteria degree are resulted. Indicators of criteria "level differentiation", "individualization" and "intensification" of educational process for information and communication technologies training quality assessment are specified.

FY 1974 report on the results of the Sunshine Project. Technology assessment of hydrogen energy technology; 1974 nendo suiso energy gijutsu no technology assessment seika hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1975-04-30

This is aimed at studying the relation between the technology development of hydrogen energy and the society. In Chapter 1, a meaning of technology assessment was examined. When applying it to the hydrogen energy technology, the paper presented what content it has. In Chapter 2, the needs for hydrogen energy in society were made clear in comparison with the energy supply/demand structure in Japan and characteristics of hydrogen energy. In Chapter 3, the paper showed what kinds of technology are being developed to meet the needs in this society and arranged viewpoints for evaluating the effectiveness of the technology. In Chapter 4, the paper studied the positioning of hydrogen energy technology in the future society, and presented as examples more than one hydrogen energy/system plans which become the base to describe the impact of the technology on the society. If taking technology assessment as a part of the communication activities between the technology development and the society as did in this study, these system plans are something like the ring for people in each field to talk with. In Chapter 5, the study made from each aspect was arranged. (NEDO)

Capital-Energy Substitution and Shifts in Factor Demand. A Meta-Analysis

Energy Technology Data Exchange (ETDEWEB)

Koetse, M.J. [Department of Spatial Economics, Vrije Universiteit Amsterdam (Netherlands); De Groot, Henri L.F. [Tinbergen Institute, Amsterdam (Netherlands); Florax, R.J.G.M. [Department of Agricultural Economics, Purdue University, West Lafayette (United States)

2006-07-01

This paper presents results of a meta-regression analysis on empirical estimates of capital-energy substitution. Theoretically it is clear that a distinction should be made between Morishima substitution elasticities and cross-price elasticities. The former represent purely technical substitution possibilities while the latter include an income effect and therefore represent economic substitution potential. We estimate a meta-regression model with separate coefficients for the two elasticity samples. Our findings suggest that primary model assumptions on returns to scale, technological change and separability of input factors matter for the outcome of a primary study. Aggregation of variables and the type of data used in empirical research are also relevant sources of systematic effect-size variation. Taking these factors into consideration, we compute ideal-typical elasticities for the short, medium and long run. The resulting figures clearly show that substitution elasticities are substantially higher than cross price elasticities. Therefore, despite considerable technical opportunities for capital-energy substitution, they are almost entirely outweighed by the negative income effect brought about by energy price increases; the short and medium run cross price elasticities are not statistically different from zero. In the long run this pattern does not hold. Our findings therefore suggest that actual changes in the demand for capital due to energy price increases take time.

New Modes of Constructive Technology Assessment for Developing Countries

DEFF Research Database (Denmark)

Christensen, David; Remmen, Arne

of transformation or co-creation in a movement from one context to another, i.e. from the North to South. The question here is how to affect a proactive intake of relevant knowledge in decision-making in a technological innovation process so as to increase the likelihood of developing sustainable solutions. A co...... into actor strategies and decision-making processes. There is a variant of ‘constructive’ technology assessment that stands out as useful in multi-actor partnership settings. Placing emphasis on interactive processes, constructive technology assessment embraces active negotiation among involved parties...... in influencing technological change. In developing countries, technology assessment has received relatively little attention, but recent developments have expressed a ‘call-to-arms’ to tailor flexible approaches by ensuring the involvement of diverse stakeholders and citizens and continual learning among...

Life Cycle Assessment of Slurry Management Technologies

DEFF Research Database (Denmark)

Wesnæs, Marianne; Wenzel, Henrik; Petersen, Bjørn Molt

This report contains the results of Life Cycle Assessments of two slurry management technologies - acidification and decentred incineration. The LCA foundation can be used by the contributing companies for evaluating the environmental sustainability of a specific technology from a holistic Life...... Cycle perspective. Through this the companies can evaluate the environmental benefits and disadvantages of introducing a specific technology for slurry management. From a societal perspective the results can contribute to a clarification of which slurry management technologies (or combination...... of technologies) having the largest potential for reducing the overall environmental impacts....

DECISION ANALYSIS AND TECHNOLOGY ASSESSMENTS FOR METAL AND MASONRY DECONTAMINATION TECHNOLOGIES

International Nuclear Information System (INIS)

Ebadian, M.A.

1999-01-01

The purpose of this investigation was to conduct a comparative analysis of innovative technologies for the non-aggressive removal of coatings from metal and masonry surfaces and the aggressive removal of one-quarter to one-inch thickness of surface from structural masonry. The technologies tested should be capable of being used in nuclear facilities. Innovative decontamination technologies are being evaluated under standard, non-nuclear conditions at the FIU-HCET technology assessment site in Miami, Florida. This study is being performed to support the OST, the Deactivation and Decommissioning (D and D) Focus Area, and the environmental restoration of DOE facilities throughout the DOE complex by providing objective evaluations of currently available decontamination technologies

Health technology assessment in Iran: challenges and views

Science.gov (United States)

Olyaeemanesh, Alireza; Doaee, Shila; Mobinizadeh, Mohammadreza; Nedjati, Mina; Aboee, Parisa; Emami-Razavi, Seyed Hassan

2014-01-01

Background: Various decisions have been made on technology application at all levels of the health system in different countries around the world. Health technology assessment is considered as one of the best scientific tools at the service of policy- makers. This study attempts to investigate the current challenges of Iran’s health technology assessment and provide appropriate strategies to establish and institutionalize this program. Methods: This study was carried out in two independent phases. In the first, electronic databases such as Medline (via Pub Med) and Scientific Information Database (SID) were searched to provide a list of challenges of Iran’s health technology assessment. The views and opinions of the experts and practitioners on HTA challenges were studied through a questionnaire in the second phase which was then analyzed by SPSS Software version 16. This has been an observational and analytical study with a thematic analysis. Results: In the first phase, seven papers were retrieved; from which, twenty- two HTA challenges in Iran were extracted by the researchers; and they were used as the base for designing a structured questionnaire of the second phase. The views of the experts on the challenges of health technology assessment were categorized as follows: organizational culture, stewardship, stakeholders, health system management, infrastructures and external pressures which were mentioned in more than 60% of the cases and were also common in the views. Conclusion: The identification and prioritization of HTA challenges which were approved by those experts involved in the strategic planning of the Department of Health Technology Assessment will be a step forward in the promotion of an evidence- based policy- making and in the production of comprehensive scientific evidence. PMID:25695015

Technology and Current Reading/Literacy Assessment Strategies

Science.gov (United States)

Balajthy, Ernest

2007-01-01

Computer-based technologies offer promise as a means to assess students and provide teachers with better understandings of their students' achievement. This article describes recent developments in computer-based and web-based reading and literacy assessment, focusing on assessment administration, information management, and report creation. In…

Substituting telecommunications for travel - Feasible or desirable

Science.gov (United States)

Van Vleck, E. M.

1974-01-01

This paper reviews recent advances in telecommunications and examines the detailed structure of travel to estimate the feasibility of substituting telecommunications for various travel objectives. The impact of travel is analyzed from a social, economic, energy, and pollution standpoint to assess the desirability of substitution. Perhaps 35-50% of the nation's travel could, in theory, be replaced by very advanced telecommunications (such as a much improved large-screen teleconferencing network), but public resistance would be massive. Much economic dislocation would result since, for example, over 25% of retail sales are travel-related. The energy savings would be modest since only 25% of the nation's energy is consumed by transportation. However, all pollution would be reduced substantially since transportation accounts for 75% of the carbon monoxide, 60% of the hydrocarbon, and 55% of the nitrogen oxide pollution in the nation. Problems related to the implementation of large-scale substitution are discussed.

Principles of sustainability science to assess alternative energy technologies

CSIR Research Space (South Africa)

Brent, AC

2009-04-01

Full Text Available , adaptive capacity, and complexity of social-ecological systems to assess the potential of such technologies for increasing the carrying capacity and improving the resilience of social-ecological systems, or to assess the resilience of the technological...

Technology-Supported Performance Assessments for Middle School Geoscience

Science.gov (United States)

Zalles, D. R.; Quellmalz, E.; Rosenquist, A.; Kreikemeier, P.

2002-12-01

Under funding from the World Bank, the U.S. Department of Education, the National Science Foundation, and the Federal Government's Global Learning and Observations to Benefit the Environment Program (GLOBE), SRI International has developed and piloted web-accessible performance assessments that measure K-12 students' abilities to use learning technologies to reason with scientific information and communicate evidence-based conclusions to scientific problems. This presentation will describe the assessments that pertain to geoscience at the middle school level. They are the GLOBE Assessments and EPA Phoenix, an instantiation of SRI's model of assessment design known as Integrative Performance Assessments in Technology (IPAT). All are publicly-available on the web. GLOBE engages students in scientific data collection and observation about the environment. SRI's classroom assessments for GLOBE provide sample student assessment tools and frameworks that allow teachers and students to assess how well students can use the data in scientific inquiry projects. Teachers can use classroom assessment tools on the site to develop integrated investigations for assessing GLOBE within their particular science curricula. Rubrics are provided for measuring students' GLOBE-related skills, and alignments are made to state, national, and international science standards. Sample investigations are provided about atmosphere, hydrology, landcover, soils, earth systems, and visualizations. The IPAT assessments present students with engaging problems rooted in science or social science content, plus sets of tasks and questions that require them to gather relevant information on the web, use reasoning strategies to analyze and interpret the information, use spreadsheets, word processors, and other productivity tools, and communicate evidence-based findings and recommendations. In the process of gathering information and drawing conclusions, students are assessed on how well they can operate

Beyond checklists: toward an ethical-constructive technology assessment

NARCIS (Netherlands)

Kiran, Asle; Oudshoorn, Nelly E.J.; Verbeek, Peter P.C.C.

2015-01-01

While many technology assessments (TAs) formally conducted by TA organizations in Europe and the USA have examined the implications of new technologies for ‘quantifiable risks’ regarding safety, health or the environment, they have largely ignored the ethical implications of those technologies.

Integration of tablet technologies in the e-laboratory of cytology: a health technology assessment.

Science.gov (United States)

Giansanti, Daniele; Pochini, Marco; Giovagnoli, Maria Rosaria

2014-10-01

Although tablet systems are becoming a powerful technology, particularly useful in every application of medical imaging, to date no one has investigated the acceptance and performance of this technology in digital cytology. The specific aims of the work were (1) to design a health technology assessment (HTA) tool to assess, in terms of performance and acceptance, the introduction of tablet technologies (wearable, portable, and non portable) in the e-laboratories of cytology and (2) to test the tool in a first significant application of digital cytology. An HTA tool was proposed operating on a domain of five dimensions of investigation comprising the basic information of the product of digital cytology, the perceived subjective quality of images, the assessment of the virtual navigation on the e-slide, the assessment of the information and communication technologies features, and the diagnostic power. Six e-slides regarding studies of cervicovaginal cytology digitalized by means of an Aperio ( www.aperio.com ) scanner and uploaded onto the www.digitalslide.it Web site were used for testing the methodology on three different network connections. Three experts of cytology successfully tested the methodology on seven tablets found suitable for the study in their own standard configuration. Specific indexes furnished by the tool indicated both a high degree of performance and subjective acceptance of the investigated technology. The HTA tool thus could be useful to investigate new tablet technologies in digital cytology and furnish stakeholders with useful information that may help them make decisions involving the healthcare system. From a global point of view the study demonstrates the feasibility of using the tablet technology in digital cytology.

Biomass Gasification Technology Assessment: Consolidated Report

Energy Technology Data Exchange (ETDEWEB)

Worley, M.; Yale, J.

2012-11-01

Harris Group Inc. (HGI) was commissioned by the National Renewable Energy Laboratory to assess gasification and tar reforming technologies. Specifically, the assessments focused on gasification and tar reforming technologies that are capable of producing a syngas suitable for further treatment and conversion to liquid fuels. HGI gathered sufficient information to analyze three gasification and tar reforming systems. This report summarizes the equipment, general arrangement of the equipment, operating characteristics, and operating severity for each technology. The order of magnitude capital cost estimates are supported by a basis-of-estimate write-up, which is also included in this report. The report also includes Microsoft Excel workbook models, which can be used to design and price the systems. The models can be used to analyze various operating capacities and pressures. Each model produces a material balance, equipment list, capital cost estimate, equipment drawings and preliminary general arrangement drawings. Example outputs of each model are included in the Appendices.

Methodology of constructive technology assessment in health care

NARCIS (Netherlands)

Douma, Kirsten F. L.; Karsenberg, Kim; Hummel, Marjan J. M.; Bueno-de-Mesquita, Jolien M.; van Harten, Wim H.

2007-01-01

OBJECTIVES: Technologies in health care are evolving quickly, with new findings in the area of biotechnological and genetic research being published regularly. A health technology assessment (HTA) is often used to answer the question of whether the new technology should be implemented into clinical

Methodology of constructive technology assessment in health care

NARCIS (Netherlands)

Douma, Kirsten F.L.; Hummel, J. Marjan; Karsenberg, Kim; van Harten, Willem H.; Bueno-de-Mesquita, Jolien M.

2007-01-01

Objectives: Technologies in health care are evolving quickly, with new findings in the area of biotechnological and genetic research being published regularly. A health technology assessment (HTA) is often used to answer the question of whether the new technology should be implemented into clinical

40 CFR 721.2577 - Copper complex of (substituted sulfonaphthyl azo substituted phenyl) disulfonaphthyl azo, amine...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Copper complex of (substituted... Copper complex of (substituted sulfonaphthyl azo substituted phenyl) disulfonaphthyl azo, amine salt... substances identified generically as copper complex of (substituted sulfonaphthyl azo substituted phenyl...

Assessment Training Effects on Student Assessment Skills and Task Performance in a Technology-Facilitated Peer Assessment

Science.gov (United States)

Liu, Xiongyi; Li, Lan

2014-01-01

This study examines the impact of an assessment training module on student assessment skills and task performance in a technology-facilitated peer assessment. Seventy-eight undergraduate students participated in the study. The participants completed an assessment training exercise, prior to engaging in peer-assessment activities. During the…

A Suite of Tools for Technology Assessment

Science.gov (United States)

2007-09-01

Saden, Povinelli & Rosen, 1989). • This was a significant change in emphasis on the part of NASA, where technology had previously viewed as merely...Cost Analysis Symposium, April 13, 2005. A Suite of Tools for Technology Assessment 24 Bibliography - continued: • Sadin, Stanley T.; Povinelli

Information technology resources assessment

Energy Technology Data Exchange (ETDEWEB)

Loken, S.C. [ed.

1993-01-01

The emphasis in Information Technology (IT) development has shifted from technology management to information management, and the tools of information management are increasingly at the disposal of end-users, people who deal with information. Moreover, the interactive capabilities of technologies such as hypertext, scientific visualization, virtual reality, video conferencing, and even database management systems have placed in the hands of users a significant amount of discretion over how these resources will be used. The emergence of high-performance networks, as well as network operating systems, improved interoperability, and platform independence of applications will eliminate technical barriers to the use of data, increase the power and range of resources that can be used cooperatively, and open up a wealth of possibilities for new applications. The very scope of these prospects for the immediate future is a problem for the IT planner or administrator. Technology procurement and implementation, integration of new technologies into the existing infrastructure, cost recovery and usage of networks and networked resources, training issues, and security concerns such as data protection and access to experiments are just some of the issues that need to be considered in the emerging IT environment. As managers we must use technology to improve competitiveness. When procuring new systems, we must take advantage of scalable resources. New resources such as distributed file systems can improve access to and efficiency of existing operating systems. In addition, we must assess opportunities to improve information worker productivity and information management through tedmologies such as distributed computational visualization and teleseminar applications.

Health Information Technology Usability Evaluation Scale (Health-ITUES) for Usability Assessment of Mobile Health Technology: Validation Study.

Science.gov (United States)

Schnall, Rebecca; Cho, Hwayoung; Liu, Jianfang

2018-01-05

Mobile technology has become a ubiquitous technology and can be particularly useful in the delivery of health interventions. This technology can allow us to deliver interventions to scale, cover broad geographic areas, and deliver technologies in highly tailored ways based on the preferences or characteristics of users. The broad use of mobile technologies supports the need for usability assessments of these tools. Although there have been a number of usability assessment instruments developed, none have been validated for use with mobile technologies. The goal of this work was to validate the Health Information Technology Usability Evaluation Scale (Health-ITUES), a customizable usability assessment instrument in a sample of community-dwelling adults who were testing the use of a new mobile health (mHealth) technology. A sample of 92 community-dwelling adults living with HIV used a new mobile app for symptom self-management and completed the Health-ITUES to assess the usability of the app. They also completed the Post-Study System Usability Questionnaire (PSSUQ), a widely used and well-validated usability assessment tool. Correlations between these scales and each of the subscales were assessed. The subscales of the Health-ITUES showed high internal consistency reliability (Cronbach alpha=.85-.92). Each of the Health-ITUES subscales and the overall scale was moderately to strongly correlated with the PSSUQ scales (r=.46-.70), demonstrating the criterion validity of the Health-ITUES. The Health-ITUES has demonstrated reliability and validity for use in assessing the usability of mHealth technologies in community-dwelling adults living with a chronic illness. ©Rebecca Schnall, Hwayoung Cho, Jianfang Liu. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 05.01.2018.

The Architecture of Chemical Alternatives Assessment.

Science.gov (United States)

Geiser, Kenneth; Tickner, Joel; Edwards, Sally; Rossi, Mark

2015-12-01

Chemical alternatives assessment is a method rapidly developing for use by businesses, governments, and nongovernment organizations seeking to substitute chemicals of concern in production processes and products. Chemical alternatives assessment is defined as a process for identifying, comparing, and selecting safer alternatives to chemicals of concern (including those in materials, processes, or technologies) on the basis of their hazards, performance, and economic viability. The process is intended to provide guidance for assuring that chemicals of concern are replaced with safer alternatives that are not likely to be later regretted. Conceptually, the assessment methods are developed from a set of three foundational pillars and five common principles. Based on a number of emerging alternatives assessment initiatives, in this commentary, we outline a chemical alternatives assessment blueprint structured around three broad steps: Scope, Assessment, and Selection and Implementation. Specific tasks and tools are identified for each of these three steps. While it is recognized that on-going practice will further refine and develop the method and tools, it is important that the structure of the assessment process remain flexible, adaptive, and focused on the substitution of chemicals of concern with safer alternatives. © 2015 Society for Risk Analysis.

Clinical Application of Antimicrobial Bone Graft Substitute in Osteomyelitis Treatment: A Systematic Review of Different Bone Graft Substitutes Available in Clinical Treatment of Osteomyelitis

Directory of Open Access Journals (Sweden)

T. A. G. van Vugt

2016-01-01

Full Text Available Osteomyelitis is a common occurrence in orthopaedic surgery, which is caused by different bacteria. Treatment of osteomyelitis patients aims to eradicate infection by debridement surgery and local and systemic antibiotic therapy. Local treatment increases success rates and can be performed with different antimicrobial bone graft substitutes. This review is performed to assess the level of evidence of synthetic bone graft substitutes in osteomyelitis treatment. According to the PRISMA statement for reporting systematic reviews, different types of clinical studies concerning treatment of osteomyelitis with bone graft substitutes are included. These studies are assessed on their methodological quality as level of evidence and bias and their clinical outcomes as eradication of infection. In the fifteen included studies, the levels of evidence were weak and in ten out of the fifteen studies there was a moderate to high risk of bias. However, first results of the eradication of infection in these studies showed promising results with their relatively high success rates and low complication rates. Due to the low levels of evidence and high risks of bias of the included studies, these results are inconclusive and no conclusions regarding the performed clinical studies of osteomyelitis treatment with antimicrobial bone graft substitutes can be drawn.

Current mHealth technologies for physical activity assessment and promotion.

Science.gov (United States)

O'Reilly, Gillian A; Spruijt-Metz, Donna

2013-10-01

Novel mobile assessment and intervention capabilities are changing the face of physical activity (PA) research. A comprehensive systematic review of how mobile technology has been used for measuring PA and promoting PA behavior change is needed. Article collection was conducted using six databases from February to June 2012 with search terms related to mobile technology and PA. Articles that described the use of mobile technologies for PA assessment, sedentary behavior assessment, and/or interventions for PA behavior change were included. Articles were screened for inclusion and study information was extracted. Analyses were conducted from June to September 2012. Mobile phone-based journals and questionnaires, short message service (SMS) prompts, and on-body PA sensing systems were the mobile technologies most utilized. Results indicate that mobile journals and questionnaires are effective PA self-report measurement tools. Intervention studies that reported successful promotion of PA behavior change employed SMS communication, mobile journaling, or both SMS and mobile journaling. mHealth technologies are increasingly being employed to assess and intervene on PA in clinical, epidemiologic, and intervention research. The wide variations in technologies used and outcomes measured limit comparability across studies, and hamper identification of the most promising technologies. Further, the pace of technologic advancement currently outstrips that of scientific inquiry. New adaptive, sequential research designs that take advantage of ongoing technology development are needed. At the same time, scientific norms must shift to accept "smart," adaptive, iterative, evidence-based assessment and intervention technologies that will, by nature, improve during implementation. © 2013 American Journal of Preventive Medicine.

Let's Be Clear(er) about Substitution A Reporting Framework to Account for Product Displacement in Life Cycle Assessment

DEFF Research Database (Denmark)

Vadenbo, Carl; Hellweg, Stefanie; Astrup, Thomas Fruergaard

2017-01-01

for the systematic reporting of information and assumptions expected to contribute to the substitution potential in order to make substitution modeling and the results thereof more transparent and interpretable. We propose a reporting framework that can also support the systematic estimation of substitution...... application. The proposed framework enables well-motivated substitution potentials to be accounted for, regardless of the chosen approach, and improves the reproducibility of comparative LCA studies of resource recovery....

TECHNOLOGY NEEDS ASSESSMENT (TNA FOR CLIMATE CHANGE MITIGATION IN AGRICULTURE SECTOR: CRITERIA, PRIORITIZING AND BARRIERS

Directory of Open Access Journals (Sweden)

Kasdi Subagyono

2010-11-01

greenhouse gas emission, yet technologies need for have not been assessed. The technology needs assessment for the agriculture sector cover paddy field, perennial crops, peat soil, and livestock. The concern of the assessment is categorized into technology options, priority/key technology, barriers, and modalities. Selected technologies are based on criteria and priority options of technology needs. Data and information have been collected from related agencies, center, institutes and other relevant sources as well as through a workshop. Technology selection process for mitigation considered general criteria of reducing GHG emissions from crops and livestock, promoting resource conservation, promoting sustainable biodiversity, promoting green energy, sustaining food security, and promoting energy alternative; and specific criteria of promoting local technology for mitigation, sustaining site-specific germ plasms, promoting simple and cheap technology for poor farmers, promoting less emission crop varieties, substituting chemical with organic fertilizers/compost, and reduce CH4 emissions. Those criteria are scored into 4 classes, i.e. high value/high relevant/high impact (score: 5, Medium value/relevant/med impact (score: 3; Low value/less relevant/less impact (score: 1; nil – not relevant/no impact (score: 0. The assessment has come up with the results that priority technologies needed for mitigation are (a low methane emitter crops varieties, appropriate fertilizing, no tillage, and intermittent irrigation for paddy fields, (b appropriate slash and burn and bio-fuel for perennial crops, (c composting manure and biogas production for livestock, and (d overcoming slash and burn, avoiding over drain and maintaining soil moisture for peat soils.

Augmented Reality Tower Technology Assessment

Science.gov (United States)

Reisman, Ronald J.; Brown, David M.

2009-01-01

Augmented Reality technology may help improve Air Traffic Control Tower efficiency and safety during low-visibility conditions. This paper presents the assessments of five off-duty controllers who shadow-controlled' with an augmented reality prototype in their own facility. Initial studies indicated unanimous agreement that this technology is potentially beneficial, though the prototype used in the study was not adequate for operational use. Some controllers agreed that augmented reality technology improved situational awareness, had potential to benefit clearance, control, and coordination tasks and duties and could be very useful for acquiring aircraft and weather information, particularly aircraft location, heading, and identification. The strongest objections to the prototype used in this study were directed at aircraft registration errors, unacceptable optical transparency, insufficient display performance in sunlight, inadequate representation of the static environment and insufficient symbology.

Using mid infrared technology as new method for the determination of the dwell time of salivary substitutes on three dimensional gingiva models

Directory of Open Access Journals (Sweden)

Karin Engelhart

2016-03-01

Full Text Available Abstract Background Many people suffer from dry mouth (xerostomia due to radiotherapy treatment of head and neck cancer, diseases like Sjogren’s syndrome or as adverse effects to prescribed medications. Salivary substitute products like gels or sprays are often used for treatment. Efficacy of those oral care products are regularly assessed by validated or even not validated questionnaires. To determine the adhesion effect over time more objectively a new and sensitive method was established. The following study was designed to assess the dwell time of different oral care products in vitro. Method Two different types of surfaces were covered with oral care products and washed using a definite protocol with artificial saliva salt solution. First, oral care gels or oral care sprays were spread to a polystyrene surface of 2.25 cm2, then onto cell based three-dimensional gingiva models. The surfaces were washed ten times with artificial saliva salt solution. The resulting washing solutions were examined using mid infrared spectroscopy in order to detect ingredients of the oral care products. Results All assessed oral care gels or oral care sprays and their components were detected very sensitive. Even traces of the products were detected in the eluent and thus enabled to differentiate the dwell times of the different products. In general, the dwell time of oral care gels on polystyrene or gingiva models was longer than that of oral care sprays. The use of gingiva models improved the differentiation between different products. Conclusions MIR spectroscopy turned out to be a sensitive method to detect salivary substitutes. Differences between single components and different products can be detected. The described method is a simple, reliable and easy process to evaluate the dwell time of oral care products in vitro and thus a useful tool to design optimised salivary substitute products. Ethics This is an in vitro study. No ethics or consent was

Technology assessment for the anesthesiologist.

Science.gov (United States)

Abenstein, J P

2006-12-01

The expense associated with modern heath care in the United States is very high, in excess of 15% of the GDP, continues to grow and has become a significant public policy issue. New technologies, defined as all drugs, devices, procedures, and organizational systems, are major contributors to rising health care costs. The use of health technology assessment tools can assist those in leadership positions in making rational decisions as to which new technologies to adopt. The classical approach is to use data from prospective, randomized, clinical trials that compare the outcomes of those treated with the new technology and the accepted therapy. Using this information and detailed economic data, the cost-effectiveness ratio can be determined. The accepted metrics are either dollars per life year saved or dollars per quality-adjusted life year saved. If the new medical intervention costs less than $50,000 to 80,000 dollars per life year saved, it is considered to be cost-effective and worthy of adoption. This kind of analysis is complex and expensive. In addition, the required information is not always available, limiting the applicability of this approach. Finally, the economic analysis often includes down-stream expense and benefit not relevant from a medical center perspective. Another approach is to focus the analysis to what impacts the medical center. This includes determining whether the technology has received the necessary approvals and has been shown to be effective, to improve health outcomes, to be at least as effective as standard therapy, and to be achievable outside the investigative setting. A fiscal analysis also must be done to determine what will it cost to acquire and operate the technology, what are the anticipated patient volumes and payer mix, and what will be the down-stream consequences to the medical center. If the process concludes that the technology works, makes a positive difference to patient care, and is fiscally and operationally

Life Cycle Assessment of an Advanced Bioethanol Technology in the Perspective of Constrained Biomass Availability

DEFF Research Database (Denmark)

Hedegaard, Karsten; Thyø, Katrine; Wenzel, Henrik

of alternative uses. Since natural gas and coal will be used as fuels for heat and power production at least within this time frame, the lost alternatives include substitution of natural gas or coal in the heat and power sector. In a case study, we investigate the environmental feasibility of using advanced...... show that for the case of this advanced bioethanol technology, in terms of reducing greenhouse emissions and fossil fuel dependency, more is lost than gained when prioritizing biomass or land for bioethanol. Technology pathways involving heat and power production and/or biogas, natural gas...

Effect of substitution of low linolenic acid soybean oil for hydrogenated soybean oil on fatty acid intake.

Science.gov (United States)

DiRienzo, Maureen A; Astwood, James D; Petersen, Barbara J; Smith, Kim M

2006-02-01

Low linolenic acid soybean oil (LLSO) has been developed as a substitute for hydrogenated soybean oil to reduce intake of trans FA while improving stability and functionality in processed foods. We assessed the dietary impact of substitution of LLSO for hydrogenated soybean oil (HSBO) used in several food categories. All substitutions were done using an assumption of 100% market penetration. The impact of this substitution on the intake of five FA and trans FA was assessed. Substitution of LLSO for current versions of HSBO resulted in a 45% decrease in intake of trans FA. Impacts on other FA intakes were within the realm of typical dietary intakes. No decrease in intake of alpha-linolenic acid was associated with the use of LLSO in place of HSBO because LLSO substitutes for HSBO that are already low in alpha-linolenic acid.

Natural-technological risk assessment and management

Science.gov (United States)

Burova, Valentina; Frolova, Nina

2016-04-01

EM-DAT statistical data on human impact and economic damages in the 1st semester 2015 are the highest since 2011: 41% of disasters were floods, responsible for 39% of economic damage and 7% of events were earthquakes responsible for 59% of total death toll. This suggests that disaster risk assessment and management still need to be improved and stay the principle issue in national and international related programs. The paper investigates the risk assessment and management practice in the Russian Federation at different levels. The method is proposed to identify the territories characterized by integrated natural-technological hazard. The maps of the Russian Federation zoning according to the integrated natural-technological hazard level are presented, as well as the procedure of updating the integrated hazard level taking into account the activity of separate processes. Special attention is paid to data bases on past natural and technological processes consequences, which are used for verification of current hazard estimation. The examples of natural-technological risk zoning for the country and some regions territory are presented. Different output risk indexes: both social and economic, are estimated taking into account requirements of end-users. In order to increase the safety of population of the Russian Federation the trans-boundaries hazards are also taken into account.

Substitution between Online and Offline Advertising: Evidence from the Carbonated Soft Drink Industry

OpenAIRE

He, Xi; Lopez, Rigoberto A.; Liu, Yizao

2015-01-01

As in previous studies on traditional media, previous work has assumed that online and offline advertising are substitutes. However, empirical evidence for this premise is lacking. This paper investigates the substitution between online advertising and offline advertising as well as the impact of the introduction of new media technology on the cost of advertising. Using a rich dataset of monthly observations for 52 carbonated soft drink brands between 2005 and 2011, we estimate a translog cos...

Knowledge in health technology assessment

DEFF Research Database (Denmark)

Tjørnhøj-Thomsen, Tine; Hansen, Helle Ploug

2011-01-01

Health systems are placing more and more emphasis on designing and delivering services that are focused on the patient, and there is a growing interest in patient aspects of health policy research and health technology assessment (HTA). Only a few HTA agencies use and invest in scientific methods...... to generate knowledge and evidence about the patient aspects of a given technology. This raises questions about how knowledge is produced in HTA reports and what kind of knowledge is considered relevant. This article uses a Danish HTA on patient education from 2009 as empirical material for a critical...

An environmental assessment system for environmental technologies

DEFF Research Database (Denmark)

Clavreul, Julie; Baumeister, Hubert; Christensen, Thomas Højlund

2014-01-01

A new model for the environmental assessment of environmental technologies, EASETECH, has been developed. The primary aim of EASETECH is to perform life-cycle assessment (LCA) of complex systems handling heterogeneous material flows. The objectives of this paper are to describe the EASETECH...

The Office for Technology Assessment with the German Parliament (TAB)

International Nuclear Information System (INIS)

Grunwald, A.; Petermann, T.

2004-01-01

TAB was created in 1990 with the aim of providing contributions to the improvement of the information base, particularly for parliamentary decision-making concerning science and technology. Among TAB's tasks are above all the conception and execution of technology assessment projects and the monitoring and analysis of important scientific and technological trends and related societal developments. TAB is managed by the Institute for Technology Assessment and Systems Analysis (ITAS) of the Karlsruhe Research Center. (orig.)

Preliminary studies on steel slag as a substitute for coarse aggregate on concrete

Directory of Open Access Journals (Sweden)

Karolina Rahmi

2017-01-01

Full Text Available The development of science and technology in the field of construction that is rapidly increasing, is always followed by the growing community needs for infrastructure facilities, such as buildings, bridges and other construction. One of the key element in that development is concrete. Due to the rapid development of science and technology in the field of construction, it’s required a building material which has better advantage than the materials of the existing building. To obtain a better building materials, one alternative is the use of waste as aggregate in concrete mixture. In this study the authors using waste steel waste (steel slag as a substitute for coarse aggregate. Steel slag used is steel waste from PT. Growth Sumatra Industry. The gravel substitution variations is 0%, 15%, and 25% and the testing was done by the slump test, compressive strength and flexural strength of concrete. From the test results obtained optimum compressive strength variation occurs in 25% substitution of steel slag gravel amounted to 40.481 MPa, whereas for the optimum bending capacity contained in variations of 25% substitution of steel slag gravel amounted to 19.592 N / mm2. And for optimum slump value obtained on the variation of normal concrete. This shows the workability of the concrete normally higher than the other variation.

Development of safety related technology and infrastructure for safety assessment

International Nuclear Information System (INIS)

Venkat Raj, V.

1997-01-01

Development and optimum utilisation of any technology calls for the building up of the necessary infrastructure and backup facilities. This is particularly true for a developing country like India and more so for an advanced technology like nuclear technology. Right from the inception of its nuclear power programme, the Indian approach has been to develop adequate infrastructure in various areas such as design, construction, manufacture, installation, commissioning and safety assessment of nuclear plants. This paper deals with the development of safety related technology and the relevant infrastructure for safety assessment. A number of computer codes for safety assessment have been developed or adapted in the areas of thermal hydraulics, structural dynamics etc. These codes have undergone extensive validation through data generated in the experimental facilities set up in India as well as participation in international standard problem exercises. Side by side with the development of the tools for safety assessment, the development of safety related technology was also given equal importance. Many of the technologies required for the inspection, ageing assessment and estimation of the residual life of various components and equipment, particularly those having a bearing on safety, were developed. This paper highlights, briefly, the work carried out in some of the areas mentioned above. (author)

ENVIRONMENTAL IMPACT ASSESSMENT OF A HEALTH TECHNOLOGY: A SCOPING REVIEW.

Science.gov (United States)

Polisena, Julie; De Angelis, Gino; Kaunelis, David; Gutierrez-Ibarluzea, Iñaki

2018-06-13

The Health Technology Expert Review Panel is an advisory body to Canadian Agency for Drugs and Technologies in Health (CADTH) that develops recommendations on health technology assessments (HTAs) for nondrug health technologies using a deliberative framework. The framework spans several domains, including the environmental impact of the health technology(ies). Our research objective was to identify articles on frameworks, methods or case studies on the environmental impact assessment of health technologies. A literature search in major databases and a focused gray literature search were conducted. The main search concepts were HTA and environmental impact/sustainability. Eligible articles were those that described a conceptual framework or methods used to conduct an environmental assessment of health technologies, and case studies on the application of an environmental assessment. From the 1,710 citations identified, thirteen publications were included. Two articles presented a framework to incorporate environmental assessment in HTAs. Other approaches described weight of evidence practices and comprehensive and integrated environmental impact assessments. Central themes derived include transparency and repeatability, integration of components in a framework or of evidence into a single outcome, data availability to ensure the accuracy of findings, and familiarity with the approach used. Each framework and methods presented have different foci related to the ecosystem, health economics, or engineering practices. Their descriptions suggested transparency, repeatability, and the integration of components or of evidence into a single outcome as their main strengths. Our review is an initial step of a larger initiative by CADTH to develop the methods and processes to address the environmental impact question in an HTA.

New Mobile Technologies

DEFF Research Database (Denmark)

Tan, Su-En; Henten, Anders

2006-01-01

This paper takes a look at Clayton Christensen 's theory of disruptive technologies and how Christensen's theory relates to other innovation theories. It also proposes a new layer of analysis to this theory to better link the technology analysis to the market analysis of any given technology...... product. This layer suggests that complementarity and substitutability are important criteria for technologies to be market disruptions or sustaining changes....

Practicability and margin for substitution processes in the energy field

International Nuclear Information System (INIS)

Mandel, H.

1975-01-01

In the past 25 years substitution processes have led to the result that energy supply of the Federal Republic of Germany is now dependent on mineral oil by more than 50 per cent. The development of prices on the mineral oil market during the last two years gave important impulses to innovations in the energy field. Already today a number of dispositions for substitution processes can be recognized which may, in conjunction with efforts for an increased rational use of the various energy carries, reduce the mineral oil share on primary energy requirements to one fourth up to year 2000. It has to be secured, that our economic system will get under control the research and development efforts which are required to gain the - at least part-wise - very exacting technologies for the use of substitution energy. The reduction of onesided dependence on mineral oil of our energy supply system is one of the most important aims in future energy politics. (orig.) [de

Report on achievements in fiscal 1998. Venture business growing type consortium - small business creating infrastructure (Research on polychloride vinyl resin substituting technology applying technology to reform surface of polymeric materials); 1998 nendo kobunshi zairyo no hyomen kaishitsu gijutsu wo oyoshita pori enka biniru jushi daitaika gijutsu ni kansuru kebnky seika hokokusho.

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

This project is intended to develop a technology to substitute polyvinyl chloride resin being regarded as the generation source of dioxines and environmental hormones in spite of being low in cost and having many excellent characteristics, with polyolefin resin having the same mechanical properties. It has become possible to improve adhesion of polyolefin, and substitute the products manufactured by using polyvinyl chloride resin currently with the polyolefin resin having about the same mechanical properties by establishing the technology to form two layers of polyolefin resin and modified polyolefin resin having polar groups, and by developing a bonding pretreatment agent using soft polyolefin resin as the base. The developed technology can be applied to developing products as targeted by the business entities participating in this project (the edge material for bath tub lids, a product currently available, and the water draining pipe as a new product). The current fiscal year has executed the following activities: (1) improvement in high-frequency weldability by means of polymer blending, (2) development of primers, (3) development of a two-layer forming technology to laminate resin layers with excellent adhesion on material surface, and (4) development of the plasma treatment technology. (NEDO)

Where’s the Transformation? Unlocking the Potential of Technology-Enhanced Assessment

Directory of Open Access Journals (Sweden)

Trudy Sweeney

2017-03-01

Full Text Available This study provides insight into technology-enhanced assessment (TEA in diverse higher education contexts. The effectiveness of using technology for assessment in higher education is still equivocal, particularly in regard to evidence of improvements in student learning. This empirical research explores the affordances that technology offers to assessment for transforming student learning. A systematic literature review, guided by an analytic survey tool, was used to identify and interrogate recent scholarly articles published in 19 international journals. From a total of 1713 articles, 139 articles were identified as being focused on the use of technology for assessment. The analytic tool guided the rigorous exploration of the literature regarding the types of technology being used, the educational goal, the type of assessment, and the degree of “transformation” afforded by the technology. Results showed that, in the sample investigated, TEA is used most frequently for formative peer learning, as part of the task design and feedback stages of the assessment cycle, and that social media has been a major affordance for this. Results are discussed with a view to fostering a future culture of inquiry and scholarship around TEA in higher education.

Revisiting Import-Substituting Industrialisation in Post-War Brazil

OpenAIRE

Colistete, Renato P.

2010-01-01

This article reassesses the classic period of Import-Substituting Industrialisation (ISI) in Brazil between 1945 and 1979. New data presented here show that Brazilian industry achieved significant labour productivity growth during the post-war years and became more technologically sophisticated, when measured by manufacturing exports and evidence of specific industries and firms. We also found that Brazil’s labour productivity growth lagged behind what was achieved in other industrialising an...

Effect of substitution of titanium by magnesium and niobium on ...

Indian Academy of Sciences (India)

Administrator

Effect of substitution of titanium by magnesium and niobium on structure and piezoelectric properties in (Bi1/2. Na1/2. )TiO3 ceramics. ZHOU CHANG-RONG*, LIU XIN-YU, LI WEI-ZHOU. † and YUAN CHANG-LAI. Department of Information Material Science and Engineering, Guilin University of Electronic Technology,. Guilin ...

[The substitution effect of leadership substitutes for transformational leadership in nursing organization].

Science.gov (United States)

Kim, Jeong-Hee

2006-04-01

This paper was conducted to examine the effects of transformational leadership behaviors, within the substitutes for leadership model (Kerr & Jermier, 1978). Data was collected from 181 staff nurses in 3 general hospitals, with self-reporting questionnaires (MLQ developed by Bass, rd-SLS developed by Podsakoff, et al., and MSQ developed by Weiss, et al.). Descriptive statistics, factor analysis, Cronbach's alpha and moderated regression analysis were used. 1) The transformational leader behaviors and substitutes for leadership each had correlations with job satisfaction. 2) The total amount of variance accounted for by the substitutes for leadership was substantially greater than by the transformational leadership behaviors. 3) Few of the substitutes variables moderated the relationships between the transformational leader behaviors and job satisfaction in a manner consistent with that specified by Howell, Dorfman, and Kerr (1986). The finding of this study suggest that leaders need to have a better understanding of those contextual variables that influence job satisfaction. Thus future research should focus attention on the moderating effects of substitutes, as well as the things that leaders can do to influence them. In addition, it may be good to examine the effects of substitutes on other criterion variables.

Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines

Directory of Open Access Journals (Sweden)

Youssef MM

2016-03-01

Full Text Available Magdy M Youssef,1,2 Reem K Arafa,3,4 Mohamed A Ismail1,21Department of Chemistry, College of Science, King Faisal University, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, 3Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, 4Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Cairo, EgyptAbstract: This research work deals with the design and synthesis of a series of substituted phenylfuranylnicotinamidines 4a–i. Facile preparation of the target compounds was achieved by Suzuki coupling-based synthesis of the nitrile precursors 3a–i, followed by their conversion to the corresponding nicotinamidines 4a–i utilizing LiN(TMS2. The antimicrobial activities of the newly synthesized nicotinamidine derivatives were evaluated against the Gram-negative bacterial strains Escherichia coli and Pseudomonas aeruginosa as well as the Gram-positive bacterial strains Staphylococcus aureus and Bacillus megaterium. The minimum inhibitory concentration values of nicotinamidines against all tested microorganisms were in the range of 10–20 µM. In specific, compounds 4a and 4b showed excellent minimum inhibitory concentration values of 10 µM against Staphylococcus aureus bacterial strain and were similar to ampicillin as an antibacterial reference. On the other hand, selected nicotinamidine derivatives were biologically screened for their cytotoxic activities against a panel of 60 cell lines representing nine types of human cancer at a single high dose at National Cancer Institute, Bethesda, MD, USA. Nicotinamidines showing promising activities were further assessed in a five-dose screening assay to determine their compound concentration causing 50% growth inhibition of tested cell (GI50, compound concentration causing 100% growth inhibition of tested cell (TGI, and compound concentration causing 50% lethality of tested

Ultrasound Promoted Synthesis of Bis(substituted pyrazol-4-ylcarbonyl-Substituted Thioureas

Directory of Open Access Journals (Sweden)

Li Xiao

2009-03-01

Full Text Available A series of novel bis(substituted pyrazol-4-ylcarbonyl-substituted thioureas have been synthesized by the reactions of substituted pyrazol-4-ylcarbonyl isothiocyanates with different diamines under ultrasound irradiation and classical heating method at 20-25 °C. In general, substantial improvement in rates and modest yields increases were observed when reactions were carried out under sonication, compared with the classical heating method. The structures of these compounds have been elucidated by elemental and spectral (IR, 1H-NMR analysis.

Projecting technology change to improve space technology planning and systems management

Science.gov (United States)

Walk, Steven Robert

2011-04-01

Projecting technology performance evolution has been improving over the years. Reliable quantitative forecasting methods have been developed that project the growth, diffusion, and performance of technology in time, including projecting technology substitutions, saturation levels, and performance improvements. These forecasts can be applied at the early stages of space technology planning to better predict available future technology performance, assure the successful selection of technology, and improve technology systems management strategy. Often what is published as a technology forecast is simply scenario planning, usually made by extrapolating current trends into the future, with perhaps some subjective insight added. Typically, the accuracy of such predictions falls rapidly with distance in time. Quantitative technology forecasting (QTF), on the other hand, includes the study of historic data to identify one of or a combination of several recognized universal technology diffusion or substitution patterns. In the same manner that quantitative models of physical phenomena provide excellent predictions of system behavior, so do QTF models provide reliable technological performance trajectories. In practice, a quantitative technology forecast is completed to ascertain with confidence when the projected performance of a technology or system of technologies will occur. Such projections provide reliable time-referenced information when considering cost and performance trade-offs in maintaining, replacing, or migrating a technology, component, or system. This paper introduces various quantitative technology forecasting techniques and illustrates their practical application in space technology and technology systems management.

Technology diffusion, product differentiation and environmental subsidies

Energy Technology Data Exchange (ETDEWEB)

McGinty, M. [Univ. of Wisconsin, Milwaukee, WI (United States). Dept. of Economics; Vries, F.P. de [Univ. of Groningen (Netherlands). Dept. of Law and Economics

2007-07-01

Technological change is often seen as the promising device that will mitigate or solve environmental problems. Policy intervention that spurs the development, adoption and diffusion of new, environmentally benign technologies therefore holds great appear for environmental authorities. Policymakers have various instruments at their disposal to affect technological diffusion, ranging from direct regulation (command-and-control strategies) to market-based instruments, such as taxes, subsidies and tradable pollution permits. This paper examines environmental subsidies as a technology diffusion policy. The authors apply evolutionary game theory to explore the relationship between subsidies for clean technology, the diffusion of that technology and the degree of product differentiation in an imperfectly competitive market. They show that the subsidy succeeds in reducing environmental damage only when the substitution effect (the reduction in pollution associated with the clean technology) exceeds the output effect (the extent that the subsidy increases output). When the substitution effect does dominate, environmental damage decreases monotonically during the diffusion process. The extent of diffusion (the degree to which clean technolgy replaces dirty) and the likelihood that the substitution effect will dominate both decrease with the extent of product differentiation. Finally, the subsidy for clean technology will spill over to the remaining dirty producers increasing their profit as well.

Expanding the applicability of Heallth Technology Assessments

DEFF Research Database (Denmark)

Draborg, Eva; Hansen, Helle Ploug

2012-01-01

The objective of the presentation is to expand the foundations of input into policy decision making relying on health technology assessments (HTA). HTAs are primarily based on systematic reviews (SR) and thereby mostly on randomized controlled trials (RCT). RCTs can be distinguished on a continuum...... between explanatory and pragmatic trials according to their level of control over variables in the study besides the examined technology. In explanatory trials emphasis are placed on internal validity in order to test the efficacy of a technology under ideal conditions while pragmatic trials emphasizes...... external validity and the effectiveness of a technology in normal daily practice. SR and HTAs favors internal valid trials and thereby proofs of possible cause-effect relationship between a technology and outcomes but at the expense of the wider perspectives of a technology. HTA have a policy...

Reactor technology assessment and selection utilizing systems engineering approach

Science.gov (United States)

Zolkaffly, Muhammed Zulfakar; Han, Ki-In

2014-02-01

The first Nuclear power plant (NPP) deployment in a country is a complex process that needs to consider technical, economic and financial aspects along with other aspects like public acceptance. Increased interest in the deployment of new NPPs, both among newcomer countries and those with expanding programs, necessitates the selection of reactor technology among commercially available technologies. This paper reviews the Systems Decision Process (SDP) of Systems Engineering and applies it in selecting the most appropriate reactor technology for the deployment in Malaysia. The integrated qualitative and quantitative analyses employed in the SDP are explored to perform reactor technology assessment and to select the most feasible technology whose design has also to comply with the IAEA standard requirements and other relevant requirements that have been established in this study. A quick Malaysian case study result suggests that the country reside with PWR (pressurized water reactor) technologies with more detailed study to be performed in the future for the selection of the most appropriate reactor technology for Malaysia. The demonstrated technology assessment also proposes an alternative method to systematically and quantitatively select the most appropriate reactor technology.

Assessment of selected furnace technologies for RWMC waste

International Nuclear Information System (INIS)

Batdorf, J.; Gillins, R.; Anderson, G.L.

1992-03-01

This report provides a description and initial evaluation of five selected thermal treatment (furnace) technologies, in support of earlier thermal technologies scoping work for application to the Idaho National Engineering Laboratory Radioactive Waste Management Complex (RWMC) buried wastes. The cyclone furnace, molten salt processor, microwave melter, ausmelt (fuel fired lance) furnace, and molten metal processor technologies are evaluated. A system description and brief development history are provided. The state of development of each technology is assessed, relative to treatment of RWMC buried waste

Substitution determination of Fmoc‐substituted resins at different wavelengths

Science.gov (United States)

Kley, Markus; Bächle, Dirk; Loidl, Günther; Meier, Thomas; Samson, Daniel

2017-01-01

In solid‐phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters, such as the number of amino acid derivative equivalents. For Fmoc‐substituted resins, substitution determination is often performed by suspending the Fmoc‐protected starting resin in 20% (v/v) piperidine in DMF to generate the dibenzofulvene–piperidine adduct that is quantified by ultraviolet–visible spectroscopy. The spectrometric measurement is performed at the maximum absorption wavelength of the dibenzofulvene–piperidine adduct, that is, at 301.0 nm. The recorded absorption value, the resin weight and the volume are entered into an equation derived from Lambert–Beer's law, together with the substance‐specific molar absorption coefficient at 301.0 nm, in order to calculate the nominal substitution. To our knowledge, molar absorption coefficients between 7100 l mol−1 cm−1 and 8100 l mol−1 cm−1 have been reported for the dibenzofulvene–piperidine adduct at 301.0 nm. Depending on the applied value, the nominal batch size may differ up to 14%. In this publication, a determination of the molar absorption coefficients at 301.0 and 289.8 nm is reported. Furthermore, proof is given that by measuring the absorption at 289.8 nm the impact of wavelength accuracy is reduced. © 2017 The Authors Journal of Peptide Science published by European Peptide Society and John Wiley & Sons Ltd. PMID:28635051

How to make participatory technology assessment in agriculture more 'participatory'

DEFF Research Database (Denmark)

Tavella, Elena

2016-01-01

the cultivation of new GM plants in Denmark. Furthermore, through this illustration, the term Participatory Technology Assessment (PTA) is redefined, thereby suggesting two additional aspects to assessing new technologies – following and evaluating policy making – to be considered in the conduct of PTA....

Technology-Enhanced Formative Assessment: A Research-Based Pedagogy for Teaching Science with Classroom Response Technology

Science.gov (United States)

Beatty, Ian D.; Gerace, William J.

2009-01-01

"Classroom response systems" (CRSs) are a promising instructional technology, but most literature on CRS use fails to distinguish between technology and pedagogy, to define and justify a pedagogical perspective, or to discriminate between pedagogies. "Technology-enhanced formative assessment" (TEFA) is our pedagogy for CRS-based science…

Feasibility Assessment of Incorporating Copper Slag as a Sand Substitute to Attain Sustainable Production Perspective in Concrete

Directory of Open Access Journals (Sweden)

Akshaykumar M. Bhoi

2018-01-01

Full Text Available Motivated by the sustainable production perspective, a laboratory testing program is exercised to ascertain the feasibility of utilizing copper slag in place of the natural fine aggregate in concrete. Totally, fifteen concrete mixtures were prepared to incorporate copper slag in place of the fine aggregate in concrete. The attributes of concrete specimens made with varying proportions of copper slag were compared (ranging from 0% to 100% substitution at a w/c ratio of 0.44, and the optimum percentage of copper slag was decided. The w/c ratio in the mix containing optimum copper slag percentage was then varied (from 0.42 to 0.36 to examine the influence of the change in the quantity of available water on the strength attributes of concrete. Concrete specimens were assessed for workability, density, compressive strength, flexural strength, and split tensile strength. SEM images and X-ray diffractograms of concrete specimens were also studied. The results obtained indicated a significant increase in workability and a small rise in the bulk density of concrete. The study concludes that substituting 60% sand with copper slag results in better compressive strength compared to control concrete and can be improved further by reducing the w/c ratio in the mix.

Technology assessment - a workable way out of the 'risk society'?

International Nuclear Information System (INIS)

Mueller-Brandeck-Bocquet, G.

1988-01-01

On the basis of concrete experience and results in the risk assessment process concerning nuclear technology in the Federal Republic of Germany it becomes apparent that technology asessment can make a contribution towards the required technology domestication. The 'risk management' of the circle of nuclear power generators and the consulting and licensing bodies having failed, a new phase of technology assessment began in 1970, whereby proponents and opponents of nuclear energy had a say. Parallel research on the safety of light water reactors and fast breeders gave valuable insight into the danger potential of nuclear energy while the latent risk of technology assessment misuse became apparent in the decision-finding process concerning the problem of radioactive waste management. In the end it were the Enquete Commission 'Future Nuclear Energy Policy' of the German Bundestag and the studies on social agreeability of energy supply systems which resulted in the perspective of a future without the use of nuclear power being a realistic option. The general findings of technology assessment, e.g. the cognition that there can be no scientific decision in favour of assuming responsibility for nuclear energy, opens up new views and possibilities for acting for the decision-makers in the field of energy policy. (orig./HSCH) [de

Assessment of Alternative RF Linac Structures for APT

Energy Technology Data Exchange (ETDEWEB)

None

1997-03-26

The APT program has been examining both normal and superconducting variants of the APT linac for the past two years. A decision on which of the two will be the selected technology will depend upon several considerations including the results of ongoing feasibility experiments, the performance and overall attractiveness of each of the design concepts, and an assessment of the system-level features of both alternatives. The primary objective of the Assessment of Alternative RF Linac Structures for APT study reported herein was to assess and compare, at the system-level, the performance, capital and life cycle costs, reliability/availability/maintainability (RAM) and manufacturing schedules of APT RF linear accelerators based upon both superconducting and normal conducting technologies. A secondary objective was to perform trade studies to explore opportunities for system optimization, technology substitution and alternative growth pathways and to identify sensitivities to design uncertainties.

Assessment of Alternative RF Linac Structures for APT

International Nuclear Information System (INIS)

None

1997-01-01

The APT program has been examining both normal and superconducting variants of the APT linac for the past two years. A decision on which of the two will be the selected technology will depend upon several considerations including the results of ongoing feasibility experiments, the performance and overall attractiveness of each of the design concepts, and an assessment of the system-level features of both alternatives. The primary objective of the Assessment of Alternative RF Linac Structures for APT study reported herein was to assess and compare, at the system-level, the performance, capital and life cycle costs, reliability/availability/maintainability (RAM) and manufacturing schedules of APT RF linear accelerators based upon both superconducting and normal conducting technologies. A secondary objective was to perform trade studies to explore opportunities for system optimization, technology substitution and alternative growth pathways and to identify sensitivities to design uncertainties

Is mobile learning a substitute for electronic learning?

OpenAIRE

Sitthiworachart, Jirarat; Joy, Mike

2008-01-01

Mobile learning is widely regarded as the next generation of learning technologies, and refers to the use of mobile devices in education to enhance learning activities. The increasing use of mobile devices has encouraged research into the capabilities of mobile learning systems. Many questions arise about mobile learning, such as whether mobile learning can be a substitute for electronic learning, what the potential benefits and problems of utilizing mobile devices in education are, and what ...

THE STUDY OF FISH SUPPLEMENT AND BUTTERFAT SUBSTITUTE EFFECT ON EXPIRY DATE OF PROCESSED CHEESE PRODUCT

Directory of Open Access Journals (Sweden)

NATALIYA LOTYSH

2015-02-01

Full Text Available The sector of functional products has top-priority meaning – it is the most convenient and natural form of introduction and enrichment of the human organism with vitamins, mineral substances, microelements and other components. Attraction into the branch of raw materials of non-milk origin – fish supplements and substitutes of butterfat – served the basis of technology development of processed cheese products of combined content, which in accordance with acting terminology are called processed cheese products. The technology of processed cheese products allows easily regulating their content by introduction of corresponding supplement that facilitates obtainment of product with set properties and content. Inclusion of meat and fish as the raw materials in the processed cheese content results in enrichment of the product with macro- and microelements, unsaturated fatty acids, except for regulation of fatty acid content of cheese products is executed by substitution of butterfat by butterfat substitute.

Assessment of Sensor Technologies for Advanced Reactors

Energy Technology Data Exchange (ETDEWEB)

Korsah, Kofi [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Vlim, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Kisner, Roger A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Britton, Jr, Charles L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wootan, D. W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Anheier, Jr, N. C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Diaz, A. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hirt, E. H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chien, H. T. [Argonne National Lab. (ANL), Argonne, IL (United States); Sheen, S. [Argonne National Lab. (ANL), Argonne, IL (United States); Bakhtiari, Sasan [Argonne National Lab. (ANL), Argonne, IL (United States); Gopalsami, S. [Argonne National Lab. (ANL), Argonne, IL (United States); Heifetz, A. [Argonne National Lab. (ANL), Argonne, IL (United States); Tam, S. W. [Argonne National Lab. (ANL), Argonne, IL (United States); Park, Y. [Argonne National Lab. (ANL), Argonne, IL (United States); Upadhyaya, B. R. [Univ. of Tennessee, Knoxville, TN (United States); Stanford, A. [Univ. of Tennessee, Knoxville, TN (United States)

2016-10-01

Sensors and measurement technologies provide information on processes, support operations and provide indications of component health. They are therefore crucial to plant operations and to commercialization of advanced reactors (AdvRx). This report, developed by a three-laboratory team consisting of Argonne National Laboratory (ANL), Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL), provides an assessment of sensor technologies and a determination of measurement needs for AdvRx. It provides the technical basis for identifying and prioritizing research targets within the instrumentation and control (I&C) Technology Area under the Department of Energy’s (DOE’s) Advanced Reactor Technology (ART) program and contributes to the design and implementation of AdvRx concepts.

Technology Audit: Assessment of Innovative Portfolio

Directory of Open Access Journals (Sweden)

Kurushina Viktoria

2016-01-01

Full Text Available The article discusses the features of the technological audit performing in the companies of oil and gas sector of Russian economy. To measure the innovations quality level the scale was developed based on the Theory of Inventive Problem Solving and the theory of technological structures. Figures of the innovations quantity by levels, volume and quality of the innovative portfolio are offered for assessment the innovative portfolio quality. The method was tested on an example of oil and gas transporting enterprises. The results of the comparative analysis of innovative portfolio are shown.

Zero-emission vehicle technology assessment. Final report

Energy Technology Data Exchange (ETDEWEB)

Woods, T.

1995-08-01

This is the final report in the Zero-Emission Vehicle (ZEV) Technology Assessment, performed for NYSERDA by Booz-Allen & Hamilton Inc. Booz-Allen wrote the final report, and performed the following tasks as part of the assessment: assembled a database of key ZEV organizations, their products or services, and plans; described the current state of ZEV technologies; identified barriers to widespread ZEV deployment and projected future ZEV technical capabilities; and estimated the cost of ZEVs from 1998 to 2004. Data for the ZEV Technology Assessment were obtained from several sources, including the following: existing ZEV industry publications and Booz-Allen files; major automotive original equipment manufacturers; independent electric vehicle manufacturers; battery developers and manufacturers; infrastructure and component developers and manufacturers; the U.S. Department of Energy, the California Air Resources Board, and other concerned government agencies; trade associations such as the Electric Power Research Institute and the Electric Transportation Coalition; and public and private consortia. These sources were contacted by phone, mail, or in person. Some site visits of manufacturers also were conducted. Where possible, raw data were analyzed by Booz-Allen staff and/or verified by independent sources. Performance data from standardized test cycles were used as much as possible.

Economical-environmental assessment on technologies producing electric energy

International Nuclear Information System (INIS)

Najafzadeh, K.

2000-01-01

Currently, the electric power industry is undergoing substantial regulatory and organizational change with respect to economical and environmental aspects. Under these circumstances, with utilization of analytic hierarchy process (AHP) concept, we consider the assessment of Technologies producing energy from financial and pollution viewpoint. AHP techniques is one of the efficient methods in analysis of complex and multi-criteria problems, which has plenty of applications. General pattern of this assessment has been introduced, and the main goal is determining of overall priority weights for each technology. With using this pattern, overall priority weights has been determined for thermal, combined cycle and Gas turbine plants. It has been cleared that relative priority of these plants will change, if relative priority of assessment criterions changes. For application of this approach, capital budgeting process and selection of some suitable technologies among the alternatives candidate for construction have been presented. In this process the objective is to maximize the sum of overall priority weights of technologies which have been identified from AHP. Constraints are about the construction budget and annual budget for emission allowances. This process is in the integer programming IP form an has been applied to three kind of power plants with reasonable assumptions

Multiple criteria decision analysis for health technology assessment.

Science.gov (United States)

Thokala, Praveen; Duenas, Alejandra

2012-12-01

Multicriteria decision analysis (MCDA) has been suggested by some researchers as a method to capture the benefits beyond quality adjusted life-years in a transparent and consistent manner. The objectives of this article were to analyze the possible application of MCDA approaches in health technology assessment and to describe their relative advantages and disadvantages. This article begins with an introduction to the most common types of MCDA models and a critical review of state-of-the-art methods for incorporating multiple criteria in health technology assessment. An overview of MCDA is provided and is compared against the current UK National Institute for Health and Clinical Excellence health technology appraisal process. A generic MCDA modeling approach is described, and the different MCDA modeling approaches are applied to a hypothetical case study. A comparison of the different MCDA approaches is provided, and the generic issues that need consideration before the application of MCDA in health technology assessment are examined. There are general practical issues that might arise from using an MCDA approach, and it is suggested that appropriate care be taken to ensure the success of MCDA techniques in the appraisal process. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Understanding differences in the diffusion of environmentally beneficial technology. Final project report

Energy Technology Data Exchange (ETDEWEB)

Blackman, A.; Boyd, J.; Simpson, R.D.; Toman, M.

1996-12-31

The factors affecting the diffusion of technical discoveries among firms and nations remain one of the most interesting and important but least understood elements of economic behavior. Recently, interest in technology diffusion has been heightened by a recognition that the spread of technologies could have important implications for environmental quality as well as for market goods and services. A specific motivation for this study was the question of how rapidly technologies that reduce greenhouse gas emissions might diffuse. Technologies in this category include technologies that improve the efficiency of fossil energy use or promote substitution of renewable energy resources. The speed with which these technologies spread could have a significant effect on the rate of accumulation of carbon in the atmosphere. From a modeling perspective, the rate of innovation and diffusion of carbon-reducing technology is known to be a crucial parameter in integrated assessments of climate change risks and policy responses. Thus, a better understanding of factors that might influence the spread of carbon-reducing technologies could be valuable in studies on long-term global change and policy assessment.

Cellular bone matrices: viable stem cell-containing bone graft substitutes.

Science.gov (United States)

Skovrlj, Branko; Guzman, Javier Z; Al Maaieh, Motasem; Cho, Samuel K; Iatridis, James C; Qureshi, Sheeraz A

2014-11-01

Advances in the field of stem cell technology have stimulated the development and increased use of allogenic bone grafts containing live mesenchymal stem cells (MSCs), also known as cellular bone matrices (CBMs). It is estimated that CBMs comprise greater than 17% of all bone grafts and bone graft substitutes used. To critically evaluate CBMs, specifically their technical specifications, existing published data supporting their use, US Food and Drug Administration (FDA) regulation, cost, potential pitfalls, and other aspects pertaining to their use. Areview of literature. A series of Ovid, Medline, and Pubmed-National Library of Medicine/National Institutes of Health (www.ncbi.nlm.nih.gov) searches were performed. Only articles in English journals or published with English language translations were included. Level of evidence of the selected articles was assessed. Specific technical information on each CBM was obtained by direct communication from the companies marketing the individual products. Five different CBMs are currently available for use in spinal fusion surgery. There is a wide variation between the products with regard to the average donor age at harvest, total cellular concentration, percentage of MSCs, shelf life, and cell viability after defrosting. Three retrospective studies evaluating CBMs and fusion have shown fusion rates ranging from 90.2% to 92.3%, and multiple industry-sponsored trials are underway. No independent studies evaluating spinal fusion rates with the use of CBMs exist. All the commercially available CBMs claim to meet the FDA criteria under Section 361, 21 CFR Part 1271, and are not undergoing FDA premarket review. The CBMs claim to provide viable MSCs and are offered at a premium cost. Numerous challenges exist in regard to MSCs' survival, function, osteoblastic potential, and cytokine production once implanted into the intended host. Cellular bone matrices may be a promising bone augmentation technology in spinal fusion surgery

Substitution determination of Fmoc-substituted resins at different wavelengths.

Science.gov (United States)

Eissler, Stefan; Kley, Markus; Bächle, Dirk; Loidl, Günther; Meier, Thomas; Samson, Daniel

2017-10-01

In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters, such as the number of amino acid derivative equivalents. For Fmoc-substituted resins, substitution determination is often performed by suspending the Fmoc-protected starting resin in 20% (v/v) piperidine in DMF to generate the dibenzofulvene-piperidine adduct that is quantified by ultraviolet-visible spectroscopy. The spectrometric measurement is performed at the maximum absorption wavelength of the dibenzofulvene-piperidine adduct, that is, at 301.0 nm. The recorded absorption value, the resin weight and the volume are entered into an equation derived from Lambert-Beer's law, together with the substance-specific molar absorption coefficient at 301.0 nm, in order to calculate the nominal substitution. To our knowledge, molar absorption coefficients between 7100 l mol -1  cm -1 and 8100 l mol -1  cm -1 have been reported for the dibenzofulvene-piperidine adduct at 301.0 nm. Depending on the applied value, the nominal batch size may differ up to 14%. In this publication, a determination of the molar absorption coefficients at 301.0 and 289.8 nm is reported. Furthermore, proof is given that by measuring the absorption at 289.8 nm the impact of wavelength accuracy is reduced. © 2017 The Authors Journal of Peptide Science published by European Peptide Society and John Wiley & Sons Ltd. © 2017 The Authors Journal of Peptide Science published by European Peptide Society and John Wiley & Sons Ltd.

Assessment vs. appraisal of ethical aspects of health technology assessment: can the distinction be upheld?

Directory of Open Access Journals (Sweden)

Sandman, Lars

2014-11-01

Full Text Available [english] An essential component of health technology assessment (HTA is the assessment of ethical aspects. In some healthcare contexts, tasks are strictly relegated to different expert groups: the HTA-agencies are limited to assessment of the technology and other actors within the health care sector are responsible for appraisal and recommendations. Ethical aspects of health technologies are considered with reference to values or norms in such a way that may be prescriptive, or offer guidance as to how to act or relate to the issue in question. Given this internal prescriptivity, the distinction between assessment and appraisal seems difficult to uphold, unless the scrutiny stops short of a full ethical analysis of the technology. In the present article we analyse the distinction between assessment and appraisal, using as an example ethical aspects of implementation of GPS-bracelets for people with dementia. It is concluded that for HTA-agencies with a strictly delineated assessment role, the question of how to deal with the internal prescriptivity of ethics may be confusing. A full ethical analysis might result in a definite conclusion as to whether the technology in question is ethically acceptable or not, thereby limiting choices for decision-makers, who are required to uphold certain ethical values and norms. At the same time, depending on the exact nature of such a conclusion, different action strategies can be supported. A positive appraisal within HTA could result in a decision on implementation, or of the technology, thereby making it available to patients, or decisions to and even the use of the technology (even if someone else will have to fund it. A neutral appraisal, giving no definite answer as to whether implementation is recommended or not, could result in a towards the technology. A negative appraisal could result in a decision to or even implementation. This paper presents an overview of the implications of different outcomes

Rapid Technology Assessment Framework for Land Logistics

Science.gov (United States)

2015-03-01

Economy, Environment, Politics SWOT Strengths, Weaknesses, Opportunities, Threats TRL Technology Readiness Level US United States WHO World Health...process fills one with the hope of great things to come. From 3-D printed organs to self-assembling asteroid -mining robots, the solution to all the...one to assess the relevant advantages of the new technologies compared to the current systems. For example, if we are considering investment in a

Association of Dietary Proportions of Macronutrients with Visceral Adiposity Index: Non-Substitution and Iso-Energetic Substitution Models in a Prospective Study.

Science.gov (United States)

Moslehi, Nazanin; Ehsani, Behnaz; Mirmiran, Parvin; Hojjat, Parvane; Azizi, Fereidoun

2015-10-26

We aimed to investigate associations between dietary macronutrient proportions and prospective visceral adiposity index changes (ΔVAI). The study included 1254 adults (18-74 years), from the Tehran Lipid and Glucose Study (TLGS), who were followed for three years. Dietary intakes were assessed twice using food frequency questionnaires. Associations of dietary macronutrient with ΔVAI and risk of visceral adiposity dysfunction (VAD) after three years were investigated. The percentage of energy intake from protein in the total population, and from fat in women, were associated with higher increases in VAI. A 5% higher energy intake from protein substituted for carbohydrate, monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids (PUFAs) was associated with higher ΔVAI. Higher energy intake from animal protein substituted for PUFAs was positively associated with ΔVAI. Substituting protein and PUFAs with MUFAs were related to higher ΔVAI. The associations were similar in men and women, but reached significance mostly among women. Risk of VAD was increased when 1% of energy from protein was replaced with MUFAs. Substituting protein for carbohydrate and fat, and fat for carbohydrate, resulted in increased risk of VAD in women. Higher dietary proportions of protein and animal-derived MUFA may be positively associated with ΔVAI and risk of VAD.

Health technology assessment in Mexico.

Science.gov (United States)

Gómez-Dantés, Octavio; Frenk, Julio

2009-07-01

The history of health technology assessment (HTA) in Mexico is examined, starting with the efforts to incorporate this topic into the policy agenda and culminating with the recent creation of a specialized public agency. Information was gathered through a bibliographic search and interviews with actors involved in HTA in Mexico. HTA efforts were developed in Mexico since the mid-1980s with the participation both of academics and of policy makers, a relationship that eventually led to the creation of the Center for Technological Excellence within the Ministry of Health. Institutionalization of HTA in resource-constrained settings requires the development of a critical mass of researchers involved in this field, the implementation of information efforts, and the establishment of strong relationships between HTA experts and policy makers.

Q46 Technology Refreshment Assessment

Science.gov (United States)

Garcia-Burgos, Axel A.

2010-01-01

This document reviews the accomplishments of the author during an internship. During this internship, the author was assigned to the End User Services Office, which coordinates and oversees a wide selection of information technologies that enhance the productivity of the workforce at NASA Kennedy Space Center. During the internship the author performed an assessment of the work of the Outsourcing Desktop Initiative for NASA (ODIN) contract.

Cost-effective policy instruments for greenhouse gas emission reduction and fossil fuel substitution through bioenergy production in Austria

International Nuclear Information System (INIS)

Schmidt, Johannes; Leduc, Sylvain; Dotzauer, Erik; Schmid, Erwin

2011-01-01

Climate change mitigation and security of energy supply are important targets of Austrian energy policy. Bioenergy production based on resources from agriculture and forestry is an important option for attaining these targets. To increase the share of bioenergy in the energy supply, supporting policy instruments are necessary. The cost-effectiveness of these instruments in attaining policy targets depends on the availability of bioenergy technologies. Advanced technologies such as second-generation biofuels, biomass gasification for power production, and bioenergy with carbon capture and storage (BECCS) will likely change the performance of policy instruments. This article assesses the cost-effectiveness of energy policy instruments, considering new bioenergy technologies for the year 2030, with respect to greenhouse gas emission (GHG) reduction and fossil fuel substitution. Instruments that directly subsidize bioenergy are compared with instruments that aim at reducing GHG emissions. A spatially explicit modeling approach is used to account for biomass supply and energy distribution costs in Austria. Results indicate that a carbon tax performs cost-effectively with respect to both policy targets if BECCS is not available. However, the availability of BECCS creates a trade-off between GHG emission reduction and fossil fuel substitution. Biofuel blending obligations are costly in terms of attaining the policy targets. - Highlights: → Costs of energy policies and effects on reduction of CO 2 emissions and fossil fuel consumption. → Particular focus on new bioenergy production technologies such as second generation biofuels. → Spatially explicit techno-economic optimization model. → CO 2 tax: high costs for reducing fossil fuel consumption if carbon capture and storage is available. → Biofuel policy: no significant reductions in CO 2 emissions or fossil fuel consumption.

Measuring skill intensity of occupations with imperfect substitutability across skill types

Czech Academy of Sciences Publication Activity Database

Pertold-Gebicka, Barbara

-, č. 421 (2010), s. 1-33 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Grant - others:GA UK(CZ) 35209 Institutional research plan: CEZ:MSM0021620846 Keywords : occupations * skill-intensity * elasticity of labor substitution * technological progress Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp421.pdf

Present situation of the development of petroleum substitution energy (Germany); Sekiyu daitai energy kaihatsu no genjo (Doitsu)

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

The paper investigates and reports the developmental trend of petroleum substitution energy in Germany. Policies for the technical development and actual introduction of petroleum substitution energy in Germany are concerned with three energies: coal, natural gas, and new energy, except nuclear energy the use of which is against public opinion. Coal is the only abundant domestic resource, but not internationally competitive because of its cost. Brown coal obtained from the open pit mining is an abundant and low-cost domestic resource, but has the environmental problem. The latest technology is actually being introduced in which the thermal power generation is integrated into gasification, and the gas/steam turbine power generation. Natural gas is advancing in the use as energy source for space heating substituting for brown coal. The technology development of new energy is promoted mainly on such wind power and solar energy as are called renewable energy. As to the development of technology using renewable energy for which the rapid increasing use is not expected in near future, the target is directed mostly to CO2 control and the third world where there are no public electric power nets. 30 refs., 10 figs., 8 tabs.

Tunable ferromagnetic resonance in La-Co substituted barium hexaferrites at millimeter wave frequencies

Science.gov (United States)

Korolev, Konstantin A.; Wu, Chuanjian; Yu, Zhong; Sun, Ke; Afsar, Mohammed N.; Harris, Vincent G.

2018-05-01

Transmittance measurements have been performed on La-Co substituted barium hexaferrites in millimeter waves. Broadband millimeter-wave measurements have been carried out using the free space quasi-optical spectrometer, equipped with a set of high power backward wave oscillators covering the frequency range of 30 - 120 GHz. Strong absorption zones have been observed in the millimeter-wave transmittance spectra of all La-Co substituted barium hexaferrites due to the ferromagnetic resonance. Linear shift of ferromagnetic resonance frequency as functions of La-Co substitutions have been found. Real and imaginary parts of dielectric permittivity of La-Co substituted barium hexaferrites have been calculated using the analysis of recorded high precision transmittance spectra. Frequency dependences of magnetic permeability of La-Co substituted barium hexaferrites, as well as saturation magnetization and anisotropy field have been determined based on Schlömann's theory for partially magnetized ferrites. La-Co substituted barium hexaferrites have been further investigated by DC magnetization to assess magnetic behavior and compare with millimeter wave data. Consistency of saturation magnetization determined independently by both millimeter wave absorption and DC magnetization have been found for all La-Co substituted barium hexaferrites. These materials seem to be quite promising as tunable millimeter wave absorbers, filters, circulators, based on the adjusting of their substitution parameters.

Approaches in Substitution of Organic Solvents

DEFF Research Database (Denmark)

Jacobsen, Thomas

2000-01-01

In substitution of harmful chemicals or products with less harmful or harmless ones, there are different approaches according to the different situations, the technical requirements to the substitutes, and the goals for the substitution. Three different cases are presented. The substitution process...

Risk-based systems analysis for emerging technologies: Applications of a technology risk assessment model to public decision making

International Nuclear Information System (INIS)

Quadrel, M.J.; Fowler, K.M.; Cameron, R.; Treat, R.J.; McCormack, W.D.; Cruse, J.

1995-01-01

The risk-based systems analysis model was designed to establish funding priorities among competing technologies for tank waste remediation. The model addresses a gap in the Department of Energy's (DOE's) ''toolkit'' for establishing funding priorities among emerging technologies by providing disciplined risk and cost assessments of candidate technologies within the context of a complete remediation system. The model is comprised of a risk and cost assessment and a decision interface. The former assesses the potential reductions in risk and cost offered by new technology relative to the baseline risk and cost of an entire system. The latter places this critical information in context of other values articulated by decision makers and stakeholders in the DOE system. The risk assessment portion of the model is demonstrated for two candidate technologies for tank waste retrieval (arm-based mechanical retrieval -- the ''long reach arm'') and subsurface barriers (close-coupled chemical barriers). Relative changes from the base case in cost and risk are presented for these two technologies to illustrate how the model works. The model and associated software build on previous work performed for DOE's Office of Technology Development and the former Underground Storage Tank Integrated Demonstration, and complement a decision making tool presented at Waste Management 1994 for integrating technical judgements and non-technical (stakeholder) values when making technology funding decisions

The NICE ADHD health technology assessment: A review and critique

Directory of Open Access Journals (Sweden)

Schlander Michael

2008-01-01

Full Text Available Abstract Background Health technology assessments (HTAs by the National Institute for Health and Clinical Excellence (NICE enjoy high levels of international attention. The present analysis addresses NICE's appraisal of methylphenidate, atomoxetine and dexamphetamine for attention-deficit/hyperactivity disorder (ADHD in children and adolescents, published in March 2006. Methods A qualitative study of NICE Technology Appraisal No. 98 was done focusing on the >600-page technology assessment report, which aimed at evaluating ADHD treatment strategies by a clinical effectiveness review and an economic analysis using meta-analytical techniques and a cost-effectiveness model. Results The technology assessment was unable to differentiate between the various drugs in terms of efficacy, and its economic model was ultimately driven by cost differences. While the assessment concluded that the economic model "clearly identified an optimal treatment strategy" with first-line dexamphetamine, the NICE appraisal committee subsequently found it impossible to distinguish between the different strategies on grounds of cost-effectiveness. Analyzing the assessment reveals gaps and inconsistencies concerning data selection (ultimately relying on a small number of short-term studies only, data synthesis (pooling of heterogeneous study designs and clinical endpoints, and economic model structure (identifying double-counting of nonresponders as a likely source of bias, alongside further methodological anomalies. Conclusion Many conclusions of the NICE technology assessment rest on shaky grounds. There remains a need for a new, state-of-the-art systematic review of ADHD treatment strategies including economic evaluation, which ideally should address outcomes beyond children's health-related quality of life, such as long-term sequelae of the disorder and caregiver burden.

Technology assessment of wind energy conversion systems

Energy Technology Data Exchange (ETDEWEB)

Meier, B. W.; Merson, T. J.

1980-09-01

Environmental data for wind energy conversion systems (WECSs) have been generated in support of the Technology Assessment of Solar Energy (TASE) program. Two candidates have been chosen to characterize the WECS that might be deployed if this technology makes a significant contribution to the national energy requirements. One WECS is a large machine of 1.5-MW-rated capacity that can be used by utilities. The other WECS is a small machine that is characteristic of units that might be used to meet residential or small business energy requirements. Energy storage systems are discussed for each machine to address the intermittent nature of wind power. Many types of WECSs are being studied and a brief review of the technology is included to give background for choosing horizontal axis designs for this study. Cost estimates have been made for both large and small systems as required for input to the Strategic Environmental Assessment Simulation (SEAS) computer program. Material requirements, based on current generation WECSs, are discussed and a general discussion of environmental impacts associated with WECS deployment is presented.

Valuing local endangered species. The role of intra-species substitutes

Energy Technology Data Exchange (ETDEWEB)

Loureiro, Maria L. [Department of Economic Analysis, Universidade de Santiago (Spain); IDEGA, Universidade de Santiago de Compostela, Campus Sur, Avda das Ciencias, S/N. 15782, Santiago de Compostela (Spain); Ojea, Elena [IDEGA, Universidade de Santiago de Compostela, Campus Sur, Avda das Ciencias, S/N. 15782, Santiago de Compostela (Spain)

2008-12-01

Valuation of endangered species is important in many circumstances, and particularly when assessing the impact of large accidental oil spills. Previous studies have tested the effects of including in the contingent valuation survey reminders about the existence of diverse substitutes (in terms of other natural resources also in danger of extinction in the same area, other programs to be valued, or alternative uses of money). We include a reminder about the existence of the same biological species not being under danger of extinction elsewhere. We believe this reminder allows individuals to make an easy assessment of the biological scarcity of the species they are supposed to value. Thus, the key difference with previous studies is that valuation of endangered species is combined with an assessment of preferences towards conservation of local and native species. Our WTP results are not sensitive to the information provided about other foreign substitutes. Implications of this finding are discussed. (author)

Valuing local endangered species. The role of intra-species substitutes

International Nuclear Information System (INIS)

Loureiro, Maria L.; Ojea, Elena

2008-01-01

Valuation of endangered species is important in many circumstances, and particularly when assessing the impact of large accidental oil spills. Previous studies have tested the effects of including in the contingent valuation survey reminders about the existence of diverse substitutes (in terms of other natural resources also in danger of extinction in the same area, other programs to be valued, or alternative uses of money). We include a reminder about the existence of the same biological species not being under danger of extinction elsewhere. We believe this reminder allows individuals to make an easy assessment of the biological scarcity of the species they are supposed to value. Thus, the key difference with previous studies is that valuation of endangered species is combined with an assessment of preferences towards conservation of local and native species. Our WTP results are not sensitive to the information provided about other foreign substitutes. Implications of this finding are discussed. (author)

Unmanned Ground Vehicle Tactical Behaviors Technology Assessment

National Research Council Canada - National Science Library

Childers, Marshal A; Bodt, Barry A; Hill, Susan G; Camden, Richard; Dean, Robert M; Dodson, William F; Sutton, Lyle G; Sapronov, Leonid

2009-01-01

During 4-14 February 2008, the U.S. Army Research Laboratory and General Dynamics Robotic Systems conducted an unmanned systems tactical behaviors technology assessment at three training areas of Ft. Indiantown Gap, PA...

Incorporating the Technology Roadmap Uncertainties into the Project Risk Assessment

International Nuclear Information System (INIS)

Bonnema, B.E.

2002-01-01

This paper describes two methods, Technology Roadmapping and Project Risk Assessment, which were used to identify and manage the technical risks relating to the treatment of sodium bearing waste at the Idaho National Engineering and Environmental Laboratory. The waste treatment technology under consideration was Direct Vitrification. The primary objective of the Technology Roadmap is to identify technical data uncertainties for the technologies involved and to prioritize the testing or development studies to fill the data gaps. Similarly, project management's objective for a multi-million dollar construction project includes managing all the key risks in accordance to DOE O 413.3 - ''Program and Project Management for the Acquisition of Capital Assets.'' In the early stages, the Project Risk Assessment is based upon a qualitative analysis for each risk's probability and consequence. In order to clearly prioritize the work to resolve the technical issues identified in the Technology Roadmap, the issues must be cross- referenced to the project's Risk Assessment. This will enable the project to get the best value for the cost to mitigate the risks

Measuring skill intensity of occupations with imperfect substitutability across skill types

Czech Academy of Sciences Publication Activity Database

Pertold-Gebicka, Barbara

-, č. 421 (2010), s. 1-33 ISSN 1211-3298 R&D Projects: GA MPS HC195/10; GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : occupations * skill-intensity * elasticity of labor substitution * technological progress Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp421.pdf

Carbon Capture: A Technology Assessment

Science.gov (United States)

2013-10-21

whereas laboratory-scale experiments typically seek to validate or obtain data for specific components of a system. Laboratory- and bench-scale processes...Plant,” Energy, vol. 35 (2010), pp. 841-850. E. Favre, R. Bounaceur, and D. Roizard, “ Biogas , Membranes and Carbon Dioxide Capture,” Journal of...pp. 1-49. 64 Favre, “ Biogas , Membranes.” Carbon Capture: A Technology Assessment Congressional Research Service 42 materials have pore sizes

Application of method of organizational congruences to substitution of organic solvents with vegetable agents for cleaning offset printing machine

Energy Technology Data Exchange (ETDEWEB)

Salerno, S [ENEA, Casaccia (Italy). Area Energia Ambiente e Salute; Tartaglia, R [Unita Sanitaria Locale 10/D, Firenze (Italy); Garzi, S; Biagioni, A [Istituto tecnico Leonardo da Vinci, Firenze (Italy)

1995-06-01

The aim of this research is the application of the method of organizational congruences before and after the substitution of organic solvents with vegetable agents for the cleaning offset printing machine in order to assess the organizational changes. A solvent free process is the goal of the SUBSPRINT project (Technology Transfer Program of the European Community). In this study it is shown how human and environmental health is improved by using vegetable agents through this change may lead to some other organizational constraints such as the time needed, the monotony and repetitiveness of the technical actions involved. The authors underline that the knowledge of the new technology impact of health help for a better understanding of the resistance to the change and help for a further amelioration of it.

THE EFFECTIVENESS OF THE IMPLEMENTATION OF TECHNOLOGY SUBSTITUTING INPATIENT TREATMENT DURING THE MEDICAL CARE PROVISION TO WOMEN WITH BENIGN GYNECOLOGICAL NEOPLASMS

Directory of Open Access Journals (Sweden)

A. A. Lobganidze

2017-01-01

Full Text Available Relevance. Over the last decades, such technology substituting inpatient treatment as outpatient treatment has been actively discussed and used in practice. Despite this fact, many problems of outpatient treatment have not been solved in full, no effective leverages contributing to creating economic incentives for increasing the volume and range of medical services in day hospitals have been found in the mandatory medical insurance system.Objective. Based on an in-depth analysis of medical care provision to women with benign gynaecological neoplasms, to offer measures for improvement of medical care in outpatient facilities, particularly by using technologies substituting inpatient treatment, and to evaluate their effectiveness.Materials and methods. A comprehensive retrospective evaluation of outpatient and inpatient medical care was conducted in St. Petersburg over the period from 2008 to 2015. The information contained in the database of billed and paid invoices of the obligatory medical insurance system of St. Petersburg was studied. For the total period of eight years, the data on medical care provision to 81 622 women suffering from benign tumors of the female reproductive organs, particularly in day hospitals, were obtained. In the period 2015–2016, medical care provision to patients with benign neoplasms of the gynecological sphere was thoroughly analyzed. In 18 women’s health departments and 19 in-patient facilities in all districts of the city, all cases of treatment of patients in the basic women’s health departments and in-patient facilities were analyzed by experts. By Taking into account the obtained results, an organizational experiment on introducing substituting technologies followed by evaluating the effectiveness of their use was developed and implemented on the basis of the medical institutions in one of the districts of St. Petersburg.Results. The activeness of outpatient facilities for treatment of women with benign

Medicineringsfejl ved generisk substitution

DEFF Research Database (Denmark)

Rölfing, Jan

2012-01-01

Generic substitution is a major cause of medical mistakes in the general population. Danish legislation obligates pharmacies to substitute prescribed medicine with the cheapest equivalent formulation, despite variations in product name, packaging, shape and colour. Consequently, medical mistakes...... occur. Scientific evidence on the consequences of generic substitution is sparse. Call upon fellow health workers to report medical mistakes to the national entities and scientific peers, in order to increase awareness and scientific evidence about the problem....

Strategic Planning Tools for Large-Scale Technology-Based Assessments

Science.gov (United States)

Koomen, Marten; Zoanetti, Nathan

2018-01-01

Education systems are increasingly being called upon to implement new technology-based assessment systems that generate efficiencies, better meet changing stakeholder expectations, or fulfil new assessment purposes. These assessment systems require coordinated organisational effort to implement and can be expensive in time, skill and other…

Generic medicines and generic substitution: contrasting perspectives of stakeholders in Ireland.

Science.gov (United States)

O'Leary, A; Usher, C; Lynch, M; Hall, M; Hemeryk, L; Spillane, S; Gallagher, P; Barry, M

2015-12-15

The Health (Pricing and Supply of Medical Goods) Act 2013 passed into law in July 2013 and legislated for generic substitution in Ireland. The aim of the study was to ascertain the knowledge and perceptions of stakeholders i.e. patients, pharmacists and prescribers, of generic medicines and to generic substitution with the passing of legislation. Three stakeholder specific questionnaires were developed to assess knowledge of and perceptions to generic medicines and generic substitution. Purposive samples of patients, prescribers and pharmacists were analysed. Descriptive quantitative and qualitative analyses were undertaken. A total of 762 healthcare professionals and 353 patients were recruited. The study highlighted that over 84% of patients were familiar with generic medicines and are supportive of the concept of generic substitution. Approximately 74% of prescribers and 84% of pharmacists were supportive of generic substitution in most cases. The main areas of concern highlighted by the healthcare professionals that might impact on the successful implementation of the policy, were the issue of bioequivalence with generic medicines, the computer software systems used at present in general practitioner (GP) surgeries and the availability of branded generics. The findings from this study identify a high baseline rate of acceptance to generic medicines and generic substitution among patients, prescribers and pharmacists in the Irish setting. The concerns of the main stakeholders provide a valuable insight into the potential difficulties that may arise in its implementation, and the need for on-going reassurance and proactive dissemination of the impact of the generic substitution policy. The existing positive attitude to generic medicines and generic substitution among key stakeholders in Ireland to generic substitution, combined with appropriate support and collaboration should result in the desired increase in rates of prescribing, dispensing and use of generic

Technology development in the field of tension between its intrinsic dynamics and the goals defined in the public discussion

International Nuclear Information System (INIS)

Joerges, B.; Bechmann, G.; Hohlfeld, R.

1985-01-01

Taking the three examples of nuclear energy, microelectronics and genetic engineering, an analytic perspective is proposed which goes beyond conventional technology assessment. A comparative approach to the analysis of these three consecutive developments is suggested focusing on their physical and social substitutional functions, relevant actor games and control mechanisms, and cultural assimilation. Finally, the issue of 'autonomy' or 'Eigendynamik' of modern science and technology is discussed. (orig.) [de

Cloud and traditional videoconferencing technology for telemedicine and distance learning.

Science.gov (United States)

Liu, Wei-Li; Zhang, Kai; Locatis, Craig; Ackerman, Michael

2015-05-01

Cloud-based videoconferencing versus traditional systems are described for possible use in telemedicine and distance learning. Differences between traditional and cloud-based videoconferencing systems are examined, and the methods for identifying and testing systems are explained. Findings are presented characterizing the cloud conferencing genre and its attributes versus traditional H.323 conferencing. Because the technology is rapidly evolving and needs to be evaluated in reference to local needs, it is strongly recommended that this or other reviews not be considered substitutes for personal hands-on experience. This review identifies key attributes of the technology that can be used to appraise the relevance of cloud conferencing technology and to determine whether migration from traditional technology to a cloud environment is warranted. An evaluation template is provided for assessing systems appropriateness.

Multi-Criteria Sustainability Assessment of Urban Sludge Treatment Technologies

DEFF Research Database (Denmark)

An, Da; Xi, Beidou; Ren, Jingzheng

2017-01-01

to determine the weights of the criteria for sustainability assessment, and extension theory was used to prioritize the alternative technologies for the treatment of urban sewage sludge and grade their sustainability performances. An illustrative case including three technologies (compositing, incineration...

Review of early assessment models of innovative medical technologies

DEFF Research Database (Denmark)

Fasterholdt, Iben; Krahn, Murray D; Kidholm, Kristian

2017-01-01

INTRODUCTION: Hospitals increasingly make decisions regarding the early development of and investment in technologies, but a formal evaluation model for assisting hospitals early on in assessing the potential of innovative medical technologies is lacking. This article provides an overview of models...

[Assessment of an educational technology in the string literature about breastfeeding].

Science.gov (United States)

de Oliveira, Paula Marciana Pinheiro; Pagliuca, Lorita Marlena Freitag

2013-02-01

The goal of this study was to assess educational technology in the string literature about breastfeeding. The study was conducted between March and September 2009 by breastfeeding experts and experts on string literature. A psychometric model was adopted as the theoretical-methodological framework. For data collection, an instrument was used to assess the content about breastfeeding and the string literature rules. The analysis was based on comparisons of the notes and critical reflections of experts. Ethical guidelines were followed during the study. After the assessments, the educational technology was adjusted until all of the experts agreed. The assessment of educational technology can reduce obstacles to information dissemination and can lead to improvements in quality of life.

Social and ethical analysis in health technology assessment.

Science.gov (United States)

Tantivess, Sripen

2014-05-01

This paper presents a review of the domestic and international literature on the assessment of the social and ethical implications of health technologies. It gives an overview of the key concepts, principles, and approaches that should be taken into account when conducting a social and ethical analysis within health technology assessment (HTA). Although there is growing consensus among healthcare experts that the social and ethical ramifications of a given technology should be examined before its adoption, the demand for this kind of analysis among policy-makers around the world, including in Thailand, has so far been lacking. Currently decision-makers mainly base technology adoption decisions using evidence on clinical effectiveness, value for money, and budget impact, while social and ethical aspects have been neglected. Despite the recognized importance of considering equity, justice, and social issues when making decisions regarding health resource allocation, the absence of internationally-accepted principles and methodologies, among other factors, hinders research in these areas. Given that developing internationally agreed standards takes time, it has been recommended that priority be given to defining processes that are justifiable, transparent, and contestable. A discussion of the current situation in Thailand concerning social and ethical analysis of health technologies is also presented.

Suitability assessment of building energy saving technologies for office buildings in cold areas of China based on an assessment framework

International Nuclear Information System (INIS)

Geng, Geng; Wang, Zhaoxia; Zhao, Jing; Zhu, Neng

2015-01-01

Highlights: • An assessment method considering economy, environment and technology is proposed. • Office buildings are classified into 3 types and weights are calculated respectively. • BESTs were summed up as 3 suitability levels. • Recommendations are proposed for adopting in design stage. - Abstract: Blind application and extensive copy of building energy saving technologies have been found very common through investigation in China. Emphases should be put on the suitability assessment when selecting and optimizing building energy saving technologies. This paper created an assessment method, namely an assessment framework to assess the suitability level of building energy saving technologies from a holistic point of view. Fuzzy analytic hierarchy process was adopted. 3 factors and 8 sub-factors were included in the framework. The office buildings were classified into 3 types to calculate weights of factors and sub-factors. The assessment framework was established for each type of office buildings. 20 energy saving technologies from surveyed cases was selected as case study. Ranks of suitability level of the assessment objects were obtained for each type of office buildings. The assessment results could be referred when selecting building energy saving technologies in the design stage

Identifying improvement potentials in cement production with life cycle assessment.

Science.gov (United States)

Boesch, Michael Elias; Hellweg, Stefanie

2010-12-01

Cement production is an environmentally relevant process responsible for 5% of total anthropogenic carbon dioxide emissions and 7% of industrial fuel use. In this study, life cycle assessment is used to evaluate improvement potentials in the cement production process in Europe and the USA. With a current fuel substitution rate of 18% in Europe and 11% in the USA, both regions have a substantial potential to reduce greenhouse gas emissions and save virgin resources by further increasing the coprocessing of waste fuels. Upgrading production technology would be particularly effective in the USA where many kiln systems with very low energy efficiency are still in operation. Using best available technology and a thermal substitution rate of 50% for fuels, greenhouse gas emissions could be reduced by 9% for Europe and 18% for the USA per tonne of cement. Since clinker production is the dominant pollution producing step in cement production, the substitution of clinker with mineral components such as ground granulated blast furnace slag or fly ash is an efficient measure to reduce the environmental impact. Blended cements exhibit substantially lower environmental footprints than Portland cement, even if the substitutes feature lower grindability and require additional drying and large transport distances. The highest savings in CO(2) emissions and resource consumption are achieved with a combination of measures in clinker production and cement blending.

Sourcebook for energy assessment. [Reference Energy Systems for 1972-2020

Energy Technology Data Exchange (ETDEWEB)

Beller, M. (ed.)

1975-12-01

An analytical approach is presented that is broadly applicable to the assessment of energy technologies and policies. Using the Reference Energy System approach, it permits the examination of the economic, environmental, and resource implications resulting from the substitution of one fuel or technology for another. Included as tools for such analyses are the necessary data and methodology, as well as a set of Reference Energy Systems covering the 1972-2020 period to serve as baselines for the perturbation analyses of interest. 46 tables, 25 figures, 71 references.

Technology and the diffusion of renewable energy

International Nuclear Information System (INIS)

Popp, David; Hascic, Ivan; Medhi, Neelakshi

2011-01-01

We consider investment in wind, solar photovoltaic, geothermal, and electricity from biomass and waste across 26 OECD countries from 1991 to 2004. Using the PATSTAT database, we obtain a comprehensive list of patents for each of these technologies throughout the world, which we use to assess the impact of technological change on investment in renewable energy capacity. We consider four alternative methods for counting patents, using two possible filters: weighting patents by patent family size and including only patent applications filed in multiple countries. For each patent count, we create knowledge stocks representing the global technological frontier. We find that technological advances do lead to greater investment, but the effect is small. Investments in other carbon-free energy sources, such as hydropower and nuclear power, serve as substitutes for renewable energy. Comparing the effectiveness of our four patent counts, we find that both using only patents filed in multiple countries and weighting by family size improve the fit of the model.

Scenario drafting to anticipate future developments in technology assessment

NARCIS (Netherlands)

Retel, Valesca; Retel, V.P.; Joore, M.A.; Rutgers, E.J.; van Harten, Willem H.

2012-01-01

Background Health Technology Assessment (HTA) information, and in particular cost-effectiveness data is needed to guide decisions, preferably already in early stages of technological development. However, at that moment there is usually a high degree of uncertainty, because evidence is limited and

Long term substitution treatment (maintenance treatment of opioid dependent persons

Directory of Open Access Journals (Sweden)

Wirl, Charlotte

2007-03-01

Full Text Available Health political background: Methadone substitution treatment in Germany is introduced in 1988 in the framework of a scientific pilot study in North Rhein Westphalia. Recent statistics show that by now a broad offer of substitution treatment exists. From 1 June 2002 to 31 December 2003 113,000 substitution treatments have been recorded as being started of which around 56,000 have been recorded as ongoing treatments by 1 December 2003. Scientific background: Substitution treatment (treatment of opioid-dependent persons using substitution substances is one part of addiction treatment. Its goals are harm reduction and the stabilisation of opioid dependent persons. Integration of opioid-dependent persons in a treatment-setting, reduction of consumption of psychoactive substances, reduction of risk behaviour (primarily related to infectious diseases, decrease of mortality and improvements concerning the social, psychic and physic situation are seen as a success of substitution treatment as maintenance therapy. Research questions: The aim of this HTA report is to investigate which indicators can be used to evaluate the effectiveness of substitution treatment. Based on these indicators an evaluation of the medical, social and economical benefit of substitution treatment - also in relation to abstinence oriented treatment - is carried out. Methods: A systematic literature search was performed in 31 international databases which yielded 2451 articles with publication date between 1995 and February 2005. Results: After a twofold selection process 32 publications were included for assessment and 276 publications were used as background literature. Despite serious restrictions due to selection bias and dropout in most studies focusing on substitution treatment, reduction of consumption of illegal opioids, reduction of risk behaviour, criminal behaviour, mortality and incidence of HIV can be seen as an empirically proven success of substitution treatment

Health technology assessment in Australia: The role of AHTAC

International Nuclear Information System (INIS)

Kearney, B.; Willis, E.

1997-01-01

This paper outlines and discusses the field of medical technology assessment and the role of the Australian Health Technology Advisory Committee (AHTAC) in that process. Developments in medical technologies have altered the way in which health care is practised and delivered. As part of its work program, AHTAC has re-evaluating some existing medical technologies to assess how and under what circumstances new developments can contribute to the alleviation of the illness and suffering of the patients. Three case studies are described. These are: magnetic resonance imaging, diagnostic ultrasound and beam and isotope radiotherapy. It is stressed that the policy task is a complex one attempting to balance the need for cost containment whilst at the same time ensuring that the processes of innovation into Australia and diffusion occur in a manner which maximizes the benefit and minimizes any harm to the Australian community

Cation Substitution in Earth‐Abundant Kesterite Photovoltaic Materials

Science.gov (United States)

Li, Jianjun; Wang, Dongxiao; Li, Xiuling; Zeng, Yu

2018-01-01

Abstract As a promising candidate for low‐cost and environmentally friendly thin‐film photovoltaics, the emerging kesterite‐based Cu2ZnSn(S,Se)4 (CZTSSe) solar cells have experienced rapid advances over the past decade. However, the record efficiency of CZTSSe solar cells (12.6%) is still significantly lower than those of its predecessors Cu(In,Ga)Se2 (CIGS) and CdTe thin‐film solar cells. This record has remained for several years. The main obstacle for this stagnation is unanimously attributed to the large open‐circuit voltage (V OC) deficit. In addition to cation disordering and the associated band tailing, unpassivated interface defects and undesirable energy band alignment are two other culprits that account for the large V OC deficit in kesterite solar cells. To capture the great potential of kesterite solar cells as prospective earth‐abundant photovoltaic technology, current research focuses on cation substitution for CZTSSe‐based materials. The aim here is to examine recent efforts to overcome the V OC limit of kesterite solar cells by cation substitution and to further illuminate several emerging prospective strategies, including: i) suppressing the cation disordering by distant isoelectronic cation substitution, ii) optimizing the junction band alignment and constructing a graded bandgap in absorber, and iii) engineering the interface defects and enhancing the junction band bending. PMID:29721421

Cation Substitution in Earth-Abundant Kesterite Photovoltaic Materials.

Science.gov (United States)

Li, Jianjun; Wang, Dongxiao; Li, Xiuling; Zeng, Yu; Zhang, Yi

2018-04-01

As a promising candidate for low-cost and environmentally friendly thin-film photovoltaics, the emerging kesterite-based Cu 2 ZnSn(S,Se) 4 (CZTSSe) solar cells have experienced rapid advances over the past decade. However, the record efficiency of CZTSSe solar cells (12.6%) is still significantly lower than those of its predecessors Cu(In,Ga)Se 2 (CIGS) and CdTe thin-film solar cells. This record has remained for several years. The main obstacle for this stagnation is unanimously attributed to the large open-circuit voltage ( V OC ) deficit. In addition to cation disordering and the associated band tailing, unpassivated interface defects and undesirable energy band alignment are two other culprits that account for the large V OC deficit in kesterite solar cells. To capture the great potential of kesterite solar cells as prospective earth-abundant photovoltaic technology, current research focuses on cation substitution for CZTSSe-based materials. The aim here is to examine recent efforts to overcome the V OC limit of kesterite solar cells by cation substitution and to further illuminate several emerging prospective strategies, including: i) suppressing the cation disordering by distant isoelectronic cation substitution, ii) optimizing the junction band alignment and constructing a graded bandgap in absorber, and iii) engineering the interface defects and enhancing the junction band bending.

Decision Gate Process for Assessment of a Technology Development Portfolio

Science.gov (United States)

Kohli, Rajiv; Fishman, Julianna; Hyatt, Mark

2012-01-01

The NASA Dust Management Project (DMP) was established to provide technologies (to TRL 6 development level) required to address adverse effects of lunar dust to humans and to exploration systems and equipment, which will reduce life cycle cost and risk, and will increase the probability of sustainable and successful lunar missions. The technology portfolio of DMP consisted of different categories of technologies whose final product is either a technology solution in itself, or one that contributes toward a dust mitigation strategy for a particular application. A Decision Gate Process (DGP) was developed to assess and validate the achievement and priority of the dust mitigation technologies as the technologies progress through the development cycle. The DGP was part of continuous technology assessment and was a critical element of DMP risk management. At the core of the process were technology-specific criteria developed to measure the success of each DMP technology in attaining the technology readiness levels assigned to each decision gate. The DGP accounts for both categories of technologies and qualifies the technology progression from technology development tasks to application areas. The process provided opportunities to validate performance, as well as to identify non-performance in time to adjust resources and direction. This paper describes the overall philosophy of the DGP and the methodology for implementation for DMP, and describes the method for defining the technology evaluation criteria. The process is illustrated by example of an application to a specific DMP technology.

Technology needs assessment (TNA) resource document for South Africa

CSIR Research Space (South Africa)

Taviv, R

2007-08-01

Full Text Available TNA(Technology needs assessment) is a requirement of Article 4.5 of the UNFCCC ‘Technology Transfer’ is a broad set of processes covering the flows of know-how, experience and equipment for mitigating or adapting to climate change amongst different...

40 CFR Appendix D to Subpart G of... - Substitutes Subject to Use Restrictions and Unacceptable Substitutes

Science.gov (United States)

2010-07-01

... the following criteria, derived from Society of Automotive Engineers (SAE) standards and recommended... Substitutes] Application Substitute Decision Conditions Comments Electronics Cleaning w/CFC-113 and MCF HFC... Sector [Acceptable Subject to Narrowed Use Limits] Application Substitute Decision Comments Electronics...

Tiger Team Assessment, Energy Technology Engineering Center

International Nuclear Information System (INIS)

1991-04-01

The Office Special Projects within the Office of Environment, Safety, and Health (EH) has the responsibility to conduct Tiger Team Assessments for the Secretary of Energy. This report presents the assessment of the buildings, facilities, and activities under the DOE/Rockwell Contract No. DE-AM03-76SF00700 for the Energy Technology Engineering Center (ETEC) and of other DOE-owned buildings and facilities at the Santa Susana Field Laboratory (SSFL) site in southeastern Ventura County, California, not covered under Contract No. DE-AM03-76SF00700, but constructed over the years under various other contracts between DOE and Rockwell International. ETEC is an engineering development complex operated for DOE by the Rocketdyne Division of Rockwell International Corporation. ETEC is located within SSFL on land owned by Rockwell. The balance of the SSFL complex is owned and operated by Rocketdyne, with the exception of a 42-acre parcel owned by the National Aeronautics and Space Administration (NASA). The primary mission of ETEC is to provide engineering, testing, and development of components related to liquid metals technology and to conduct applied engineering development of emerging energy technologies

Tiger Team Assessment, Energy Technology Engineering Center

Energy Technology Data Exchange (ETDEWEB)

1991-04-01

The Office Special Projects within the Office of Environment, Safety, and Health (EH) has the responsibility to conduct Tiger Team Assessments for the Secretary of Energy. This report presents the assessment of the buildings, facilities, and activities under the DOE/Rockwell Contract No. DE-AM03-76SF00700 for the Energy Technology Engineering Center (ETEC) and of other DOE-owned buildings and facilities at the Santa Susana Field Laboratory (SSFL) site in southeastern Ventura County, California, not covered under Contract No. DE-AM03-76SF00700, but constructed over the years under various other contracts between DOE and Rockwell International. ETEC is an engineering development complex operated for DOE by the Rocketdyne Division of Rockwell International Corporation. ETEC is located within SSFL on land owned by Rockwell. The balance of the SSFL complex is owned and operated by Rocketdyne, with the exception of a 42-acre parcel owned by the National Aeronautics and Space Administration (NASA). The primary mission of ETEC is to provide engineering, testing, and development of components related to liquid metals technology and to conduct applied engineering development of emerging energy technologies.

Technology enhanced peer learning and peer assessment

DEFF Research Database (Denmark)

Henriksen, Christian Bugge; Bregnhøj, Henrik; Rosthøj, Susanne

2016-01-01

This paper explores the application of learning designs featuring formalised and structured technology enhanced peer learning. These include student produced learning elements, peer review discussions and peer assessment in the BSc/MSc level summer course Restoration of European Ecosystems and Fr...... be a huge benefit from developing learning design patterns that facilitate informal peer learning and reinforce knowledge sharing practices.......This paper explores the application of learning designs featuring formalised and structured technology enhanced peer learning. These include student produced learning elements, peer review discussions and peer assessment in the BSc/MSc level summer course Restoration of European Ecosystems...... and Freshwaters (REEF), the Master thesis preparation seminars for the Master of Public Health (MPH) and the MOOC course Global Environmental Management (GEM). The application of student produced learning elements and peer review discussions is investigated by analyzing quotes from course evaluations...

Cleaner production technology for the NDT industry

International Nuclear Information System (INIS)

Relunia, Estrella D.; Mateo, Alejandro J.

2001-01-01

This paper discusses te wastes generated from the conduct of nondestructive testing (NDT) techniques and operations like NDT film processing and the systems to reduce water pollution and the film system quality control. Discussions on clean technology production concepts and philosophy is also discussed. A case study on cleaner production technology where a process and equipment modifications and a product substitution were implemented is presented. The equipment modification and product substitution eliminated the use of 1,1,1-trichloroethane in its cleaning operation. (Author)

Optimal ordering quantities for substitutable deteriorating items under joint replenishment with cost of substitution

Science.gov (United States)

Mishra, Vinod Kumar

2017-09-01

In this paper we develop an inventory model, to determine the optimal ordering quantities, for a set of two substitutable deteriorating items. In this inventory model the inventory level of both items depleted due to demands and deterioration and when an item is out of stock, its demands are partially fulfilled by the other item and all unsatisfied demand is lost. Each substituted item incurs a cost of substitution and the demands and deterioration is considered to be deterministic and constant. Items are order jointly in each ordering cycle, to take the advantages of joint replenishment. The problem is formulated and a solution procedure is developed to determine the optimal ordering quantities that minimize the total inventory cost. We provide an extensive numerical and sensitivity analysis to illustrate the effect of different parameter on the model. The key observation on the basis of numerical analysis, there is substantial improvement in the optimal total cost of the inventory model with substitution over without substitution.

Large Deployable Reflector (LDR) system concept and technology definition study. Volume 2: Technology assessment and technology development plan

Science.gov (United States)

Agnew, Donald L.; Jones, Peter A.

1989-01-01

A study was conducted to define reasonable and representative LDR system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume presents thirteen technology assessments and technology development plans, as well as an overview and summary of the LDR concepts. Twenty-two proposed augmentation projects are described (selected from more than 30 candidates). The five LDR technology areas most in need of supplementary support are: cryogenic cooling; astronaut assembly of the optically precise LDR in space; active segmented primary mirror; dynamic structural control; and primary mirror contamination control. Three broad, time-phased, five-year programs were synthesized from the 22 projects, scheduled, and funding requirements estimated.

Technologies for Interactive Learning and Assessment Content Development

Science.gov (United States)

Gusev, Marjan; Ristov, Sasko; Armenski, Goce

2016-01-01

Recent technology trends evolved the student assessment from traditional ones ("pen-and-paper" and "face-to-face") to modern e-Assessment system. These modern approaches allow the teachers to conduct and evaluate an exam with huge number of students in a short period of time. Even more important, both the teacher and the…

Life cycle assessment of waste paper management

DEFF Research Database (Denmark)

Merrild, Hanna Kristina; Damgaard, Anders; Christensen, Thomas Højlund

2008-01-01

The significance of technical data, as well as the significance of system boundary choices, when modelling the environmental impact from recycling and incineration of waste paper has been studied by a life cycle assessment focusing oil global warming potentials. The consequence of choosing...... results. The modelling showed that recycling of paper, from a life cycle point of view, is environmentally equal or better than incineration with energy recovery only when the recycling technology is at a high environmental performance level. However, the modelling also showed that expanding the system...... a specific set of data for the reprocessing technology, the virgin paper manufacturing technology and the incineration technology, as well as the importance of the recycling rate Was Studied. Furthermore, the system was expanded to include forestry and to include fossil fuel energy substitution from saved...

Substituting natural gas heating for electric heating: assessment of the energy and environmental effects in Ontario

International Nuclear Information System (INIS)

Rosen, M.A.; Sy, E.; Gharghouri, P.

1996-01-01

A study was conducted to find practical ways to reduce Ontario's energy consumption and environmental emissions. A major portion of the study focused on the advantages of cogeneration in certain regions and sectors of Ontario. Substituting direct fuel heating with natural gas for electric heating was the principal recommendation. Results of a technical analysis of the effects of substituting electric heating with natural gas heating were described. One of the benefits of this substitution would be reduced fuel energy requirements for direct heating, relative to the two-step process of electricity generation followed by electric heating. It was suggested that natural gas should still be used for electricity generation because natural gas has many advantages as an electricity supply option including reductions in coal and uranium use and related emissions. It was recommended that developers and designers of energy systems seriously consider this option. 33 refs., 2 tabs., 4 figs

Output and substitution elasticities of energy and implications for renewable energy expansion in the ECOWAS region

International Nuclear Information System (INIS)

Wesseh, Presley K.; Lin, Boqiang

2016-01-01

This study estimates output and substitution elasticities of renewable energy and nonrenewable energy for the Economic Community of West African States (ECOWAS) and discusses implications for expanding the former. The results show that nonrenewable energy promises greater benefits for ECOWAS economic transition, with output elasticities averaging between 0.052–0.579 and −0.055 to 0.223 for nonrenewable energy and renewable energy respectively. Overall estimated technological progress is low (−0.5% to 2.6%); the bulk coming from input efficiency. Substitution elasticities (0.02–0.94) suggest potential for switching towards renewable energy. Notwithstanding, scale, economics and sitting problems inherent in renewable power generation challenge the opportunities for energy substitution. A sustainable policy solution, therefore, appears to be one favoring scaled and efficient electricity generation from fossil energy in the short-run with a gradual switch towards renewable power in the long-run. In general, the applied model provides insights that energy efficiency enhances sustainable growth by propelling technological advancement especially when technical change is scale-biased and factor-augmenting. The study also provides insights that impacts of exogenous shocks to inputs are temporary, and hence, do not jeopardize efforts aimed at scaling output through increased and efficient use of labor, capital and energy; especially nonrenewable energy. - Highlights: • Output and substitution elasticities of energy are estimated for the ECOWAS region. • Nonrenewable energy promises greater opportunities for economic growth. • Technical progress is low and driven mainly by the efficiency of inputs. • Energy efficiency drives technological innovation. • Potential of switching towards renewable energy is high but suffers feasibility gaps.

Vocal Sight-Reading Assessment: Technological Advances, Student Perceptions, and Instructional Implications

Science.gov (United States)

Henry, Michele

2015-01-01

This study investigated choral singers' comfort level using computer technology for vocal sight-reading assessment. High school choral singers (N = 138) attending a summer music camp completed a computer-based sight-reading assessment and accompanying pre- and posttest surveys on their musical backgrounds and perceptions about technology. A large…

The shortage of medical workers in Sub-Saharan Africa and substitution policy

OpenAIRE

Bourgain, Arnaud; Pieretti, Patrice; Zou, Benteng

2011-01-01

Substitution policies are strategies sometimes chosen in Sub-Saharan Africa for curtailing the shortage of health professionals especially caused by the outflow of medical personnel. The aim of our contribution is to propose a way to assess the merits and drawbacks of substitution policies by developing a simple growth model of healthcare productivity with medical brain drain. Within this framework, we use a medical care production function of the CES type which aggregates low and high specia...

Synthesis, characterization and structural refinement of polycrystalline uranium substituted zirconolite

International Nuclear Information System (INIS)

Shrivastava, O.P.; Narendra Kumar; Sharma, I.B.

2005-01-01

Ceramic precursors of Zirconolite (CaZrTi 2 O 7 ) family have a remarkable property of substitution Zr 4+ cationic sites. This makes them potential material for nuclear waste management in 'synroc' technology. In order to simulate the mechanism of partial substitution of zirconium by tetravalent actinides, a solid phase of composition CaZr 0.95 U 0.5 Ti 2 O 7 has been synthesized through ceramic route by taking calculated quantities of oxides of Ca, Ti and nitrates of uranium and zirconium respectively. Solid state synthesis has been carried out by repeated pelletizing and sintering the finely powdered oxide mixture in a muffle furnace at 1050 degC. The polycrystalline solid phase has been characterized by its typical powder diffraction pattern. Step analysis data has been used for ab initio calculation of structural parameters. The uranium substituted zirconolite crystallizes in monoclinic symmetry with space group C2/c (15). The following unit cell parameters have been calculated: a =12.4883(15), b =7.2448(5), c 11.3973(10) and β = 100.615(9)0. The structure was refined to satisfactory completion. The Rp and Rwp are found to be 7.48% and 9.74% respectively. (author)

Statistical Physics of Complex Substitutive Systems

Science.gov (United States)

Jin, Qing

Diffusion processes are central to human interactions. Despite extensive studies that span multiple disciplines, our knowledge is limited to spreading processes in non-substitutive systems. Yet, a considerable number of ideas, products, and behaviors spread by substitution; to adopt a new one, agents must give up an existing one. This captures the spread of scientific constructs--forcing scientists to choose, for example, a deterministic or probabilistic worldview, as well as the adoption of durable items, such as mobile phones, cars, or homes. In this dissertation, I develop a statistical physics framework to describe, quantify, and understand substitutive systems. By empirically exploring three collected high-resolution datasets pertaining to such systems, I build a mechanistic model describing substitutions, which not only analytically predicts the universal macroscopic phenomenon discovered in the collected datasets, but also accurately captures the trajectories of individual items in a complex substitutive system, demonstrating a high degree of regularity and universality in substitutive systems. I also discuss the origins and insights of the parameters in the substitution model and possible generalization form of the mathematical framework. The systematical study of substitutive systems presented in this dissertation could potentially guide the understanding and prediction of all spreading phenomena driven by substitutions, from electric cars to scientific paradigms, and from renewable energy to new healthy habits.

Innovate or imitate? Behavioural technological change

NARCIS (Netherlands)

Hommes, C.; Zeppini, P.

2014-01-01

We propose a behavioural model of technological change with evolutionary switching between costly innovators and free imitators, and study the endogenous interplay of innovation decisions, market price dynamics and technological progress. Innovation and imitation are strategic substitutes and

The role of surgeons in identifying emerging technologies for health technology assessment.

Science.gov (United States)

Stafinski, Tania; Topfer, Leigh-Ann; Zakariasen, Ken; Menon, Devidas

2010-04-01

Health technology assessment (HTA) is a tool intended to help policy-makers decide which technologies to fund. However, given the proliferation of new technologies, it is not possible to undertake an HTA of each one before it becomes funded. Consequently, "horizon-scanning" processes have been developed to identify emerging technologies that are likely to have a substantial impact on clinical practice. Although the importance of physicians in the adoption of new technologies is well recognized, their role in horizon scanning in Canada has been limited. The purpose of this project was to pilot an approach to engage physicians, specifically surgeons, in provincial horizon-scanning activities. We invited 18 surgeons from Alberta's 2 medical schools to a horizon-scanning workshop to solicit their views on emerging technologies expected to impact surgical practice within the next 5 years and/or the importance of different attributes or characteristics of new technologies. Surgeons, regardless of specialty, identified developments designed to enhance existing minimally invasive surgical techniques, such as endoscopic, robotic and image-guided surgery. Several nonsurgical areas, including molecular genetics and nano technology, were also identified. Of the 13 technology attributes discussed, safety or risk, effectiveness and feasibility were rated as most important. Lastly, participating surgeons expressed an interest in becoming further involved in local HTA initiatives. Surgeons, as adopters and users of health technologies, represent an important and accessible information source for identifying emerging technologies for HTA. A more formal, ongoing relationship between the government, HTA and surgeons may help to optimize the use of HTA resources.

Wearable technology for spine movement assessment: A systematic review

OpenAIRE

Papi, Enrica; Koh, Woon Senn; McGregor, Alison H.

2017-01-01

Continuous monitoring of spine movement function could enhance our understanding of low back pain development. Wearable technologies have gained popularity as promising alternative to laboratory systems in allowing ambulatory movement analysis. This paper aims to review the state of art of current use of wearable technology to assess spine kinematics and kinetics. Four electronic databases and reference lists of relevant articles were searched to find studies employing wearable technologies t...

Assessment of Wearable Sensor Technologies for Biosurveillance

Science.gov (United States)

2014-11-01

include: textile-based wearable sensors, epidermal tattoos, DNA and protein sensors, forensic detection of explosives, remote environmental sensing...Assessment of Wearable Sensor Technologies for Biosurveillance P a g e 4 3 David L. Hirschberg, PhD Assistant Professor, Clinical Pathology

Technology enhanced peer learning and peer assessment

DEFF Research Database (Denmark)

Henriksen, Christian Bugge; Bregnhøj, Henrik; Rosthøj, Susanne

2016-01-01

This paper explores the application of learning designs featuring formalised and structured technology enhanced peer learning. These include student produced learning elements, peer review discussions and peer assessment in the BSc/MSc level summer course Restoration of European Ecosystems...... and Freshwaters (REEF), the Master thesis preparation seminars for the Master of Public Health (MPH) and the MOOC course Global Environmental Management (GEM). The application of student produced learning elements and peer review discussions is investigated by analyzing quotes from course evaluations...... and performing focus group interviews. The application of peer assessment is investigated by analyzing the agreement of peer assessment between students assessing the same assignment. Our analyses confirm previous research on the value of peer learning and peer assessment and we argue that there could also...

The Response of Old Technology Incumbents to Technological Competition - Does the Sailing Ship Effect Exist?

DEFF Research Database (Denmark)

Howells, John

This article investigates whether firms react to a radical technological substitution threat by a deliberate acceleration of innovation in their existing technology - the 'sailing ship effect'. It has been argued that the effect is both significant and widespread and warrants a reexamination of our...

Techno-experiential design assessment and media experience database: A method for emerging technology assessment

OpenAIRE

Schick, Dan

2005-01-01

This thesis evaluates the Techno-Experiential Design Assessment (TEDA) for social research on new media and emerging technology. Dr. Roman Onufrijchuk developed TEDA to address the shortcomings of current methods designed for studying existing technologies. Drawing from the ideas of Canadian media theorist Marshall McLuhan, TEDA focuses on the environmental changes introduced by a new technology into a user's life. I describe the key components of the TEDA methodology and provide examples of ...

Stiffness compatibility of coralline hydroxyapatite bone substitute under dynamic loading

Institute of Scientific and Technical Information of China (English)

REN ChaoFeng; HOU ZhenDe; ZHAO Wei

2009-01-01

When hydroxyapatite bone substitutes are implanted in human bodies, bone tissues will grow into their porous structure, which will reinforce their strength and stiffness. The concept of mechanical com-patibility of bone substitutes implies that their mechanical properties are similar to the bone tissues around, as if they were part of the bone. The mechanical compatibility of bone substitutes includes both static and dynamic behavior, due to the mechanical properties of bone depending on the strain rate. In this study, split Hopkinson pressure bar technique (SHPB) was employed to determine the dy-namic mechanical properties of coralline hydroxyapatite, bones with and bones without organic com-ponents, and their dynamic stress-strain curves of the three materials were obtained. The mechanical effects of collagens in bone were assessed, by comparing the difference between the Young's moduli of the three materials. As the implanted bone substitute becomes a part of bone, it can be regarded as an inclusion composite. The effective modulus of the composite was also evaluated in order to estimate its mechanical compatibility on stiffness. The evaluated result shows that the suitable porosity of HA is0.8, which is in favor of both static and dynamic stiffness compatibility.

QuEST: Qualifying Environmentally Sustainable Technologies

Science.gov (United States)

Lewis, Pattie

2012-01-01

Articles in this issue inlude: (1) Foundation of Technology Evaluation for Environmental Risk Mitigation Principal Center (TEERM) Technology Evaluation is Testing and Qualification, (2) Materials Management and Substitution Efforts, (3 Recycling and Pollution Control Efforts, and (4) Remediation Efforts

Biologic and synthetic skin substitutes: An overview.

Science.gov (United States)

Halim, Ahmad Sukari; Khoo, Teng Lye; Mohd Yussof, Shah Jumaat

2010-09-01

The current trend of burn wound care has shifted to more holistic approach of improvement in the long-term form and function of the healed burn wounds and quality of life. This has demanded the emergence of various skin substitutes in the management of acute burn injury as well as post burn reconstructions. Skin substitutes have important roles in the treatment of deep dermal and full thickness wounds of various aetiologies. At present, there is no ideal substitute in the market. Skin substitutes can be divided into two main classes, namely, biological and synthetic substitutes. The biological skin substitutes have a more intact extracellular matrix structure, while the synthetic skin substitutes can be synthesised on demand and can be modulated for specific purposes. Each class has its advantages and disadvantages. The biological skin substitutes may allow the construction of a more natural new dermis and allow excellent re-epithelialisation characteristics due to the presence of a basement membrane. Synthetic skin substitutes demonstrate the advantages of increase control over scaffold composition. The ultimate goal is to achieve an ideal skin substitute that provides an effective and scar-free wound healing.

Biologic and synthetic skin substitutes: An overview

Directory of Open Access Journals (Sweden)

Halim Ahmad

2010-10-01

Full Text Available The current trend of burn wound care has shifted to more holistic approach of improvement in the long-term form and function of the healed burn wounds and quality of life. This has demanded the emergence of various skin substitutes in the management of acute burn injury as well as post burn reconstructions. Skin substitutes have important roles in the treatment of deep dermal and full thickness wounds of various aetiologies. At present, there is no ideal substitute in the market. Skin substitutes can be divided into two main classes, namely, biological and synthetic substitutes. The biological skin substitutes have a more intact extracellular matrix structure, while the synthetic skin substitutes can be synthesised on demand and can be modulated for specific purposes. Each class has its advantages and disadvantages. The biological skin substitutes may allow the construction of a more natural new dermis and allow excellent re-epithelialisation characteristics due to the presence of a basement membrane. Synthetic skin substitutes demonstrate the advantages of increase control over scaffold composition. The ultimate goal is to achieve an ideal skin substitute that provides an effective and scar-free wound healing.

Technological pedagogical content knowledge of prospective mathematics teachers regarding evaluation and assessment

Directory of Open Access Journals (Sweden)

Ercan Atasoy

2016-04-01

Full Text Available The ‘technology integrated assessment process’ is an innovative method to capture and determine students’ understanding of mathematics. This assessment process is claimed to provide a singular dynamism for teaching and learning activities and it is also claimed to be of the most important elements of instruction in the educational system. In this sense, this study aims to investigate technological pedagogical content knowledge (TPACK of prospective mathematics teachers regarding the ‘evaluation’ and ‘assessment’ process. To achieve this aim, the method of qualitative research was conducted with 20 teachers. Video records and lesson plans were collected and a Mathematics Teacher TPACK Development Model was utilized to reveal themes and key features of the data. The findings revealed that, although the majority of teachers stated that they would like to use technology-integrated tools in the assessment and evaluation processes, they strongly preferred to use traditional assessment and evaluation techniques, such as pen and paper activities, multiple-choice questions in virtual environments, etc. Hence, the evidence suggests that teachers would be unable to use appropriately the technological assessment process in order to reveal students’ understanding of mathematics. As seen from the teachers’ lectures, they perceived that technology would be suitable for evaluation and assessment but in a limited way.

Sustainability assessment of renewable power and heat generation technologies

International Nuclear Information System (INIS)

Dombi, Mihály; Kuti, István; Balogh, Péter

2014-01-01

Rationalisation of consumption, more efficient energy usage and a new energy structure are needed to be achieved in order to shift the structure of energy system towards sustainability. The required energy system is among others characterised by intensive utilisation of renewable energy sources (RES). RES technologies have their own advantages and disadvantages. Nevertheless, for the strategic planning there is a great demand for the comparison of RES technologies. Furthermore, there are additional functions of RES utilisation expected beyond climate change mitigation, e.g. increment of employment, economic growth and rural development. The aim of the study was to reveal the most beneficial RES technologies with special respect to sustainability. Ten technologies of power generation and seven technologies of heat supply were examined in a multi-criteria sustainability assessment frame of seven attributes which were evaluated based on a choice experiment (CE) survey. According to experts the most important characteristics of RES utilisation technologies are land demand and social impacts i.e. increase in employment and local income generation. Concentrated solar power (CSP), hydropower and geothermal power plants are favourable technologies for power generation, while geothermal district heating, pellet-based non-grid heating and solar thermal heating can offer significant advantages in case of heat supply. - highlights: • We used choice experiment to estimate the weights of criteria for the sustainability assessment of RES technologies. • The most important attributes of RES technologies according to experts are land demand and social impacts. • Concentrated solar power (CSP), hydropower and geothermal power plants are advantageous technologies for power generation. • Geothermal district heating, pellet-based non-grid heating and solar thermal heating are favourable in case of heat supply

Making Use of the New Student Assessment Standards To Enhance Technological Literacy.

Science.gov (United States)

Russell, Jill

2003-01-01

Describes the student assessment standards outlined in "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards," a companion to the "Standards for Technological Literacy." Discusses how the standards apply to everyday teaching practices. (JOW)

Process for Selecting System Level Assessments for Human System Technologies

Science.gov (United States)

Watts, James; Park, John

2006-01-01

The integration of many life support systems necessary to construct a stable habitat is difficult. The correct identification of the appropriate technologies and corresponding interfaces is an exhaustive process. Once technologies are selected secondary issues such as mechanical and electrical interfaces must be addressed. The required analytical and testing work must be approached in a piecewise fashion to achieve timely results. A repeatable process has been developed to identify and prioritize system level assessments and testing needs. This Assessment Selection Process has been defined to assess cross cutting integration issues on topics at the system or component levels. Assessments are used to identify risks, encourage future actions to mitigate risks, or spur further studies.

Assessment of impacts from different waste treatment and waste disposal technologies: Regional Management Plan

International Nuclear Information System (INIS)

Robertson, B.C.; Sutherland, A.A.

1986-01-01

This report presents assessments of treatment and disposal technologies that appear to be appropriate for use in regional facilities in the Midwest Compact Region. The treatment technologies assessed: compaction with a supercompactor; incineration; and incineration followed by solidfication of the incinerator ash. The disposal technologies assessed are: shallow land burial, considered a baseline for comparison of other technologies; below-ground vaults; abov-groudn vaults; the earth mounded concrete bunker, a technology developed in France; improved shallow land burial, essentially deeper burial; modular concrete canister disposal; mined cavities (both new and existing); and unlined augered holes; and lined augered holes. The teatment technologies are assessed primarily in terms of the their impact on the waste management system, and generally not comparatively. The dispoal technologies are assessed relative to the present standard practice shallow land burial; shallow land burial was slected as a frame of reference because it has an experience base spanning several decades, not because of any preferential characteristics. 20 refs., 5 tabs

ASSESSING INDIVIDUAL PERFORMANCE ON INFORMATION TECHNOLOGY ADOPTION: A NEW MODEL

OpenAIRE

Diah Hari Suryaningrum

2012-01-01

This paper aims to propose a new model in assessing individual performance on information technology adoption. The new model to assess individual performance was derived from two different theories: decomposed theory of planned behavior and task-technology fit theory. Although many researchers have tried to expand these theories, some of their efforts might lack of theoretical assumptions. To overcome this problem and enhance the coherence of the integration, I used a theory from social scien...

What Do They Understand? Using Technology to Facilitate Formative Assessment

Science.gov (United States)

Mitten, Carolyn; Jacobbe, Tim; Jacobbe, Elizabeth

2017-01-01

Formative assessment is so important to inform teachers' planning. A discussion of the benefits of using technology to facilitate formative assessment explains how four primary school teachers adopted three different apps to make their formative assessment more meaningful and useful.

In Situ Remediation Integrated Program, Evaluation and assessment of containment technology

International Nuclear Information System (INIS)

Gerber, M.A.; Fayer, M.J.

1994-04-01

The In Situ Remediation Integrated Program (ISRIP) was established by the US Department of Energy (DOE) to advance the state-of-the art of innovative in situ remediation technologies to the point of demonstration and to broaden the applicability of these technologies to the widely varying site remediation requirements throughout the DOE complex. This program complements similar ongoing integrated demonstration programs being conducted at several DOE sites. The ISRIP has been conducting baseline assessments on in situ technologies to support program planning. Pacific Northwest Laboratory conducted an assessment and evaluation of subsurface containment barrier technology in support of ISRIP's Containment Technology Subprogram. This report summarizes the results of that activity and provides a recommendation for priortizing areas in which additional research and development is needed to advance the technology to the point of demonstration in support of DOE's site restoration activities

William Nierenberg: blockbuster. [Recommendations as alternative or substitution fuel

Energy Technology Data Exchange (ETDEWEB)

1977-12-01

An interview with William Nierenberg, Univ. of California, Berkeley and Scripps Institution of Oceanography, elicits the physicist/environmentalist's determination to expedite the application of available technical solutions. His success in penetrating social and institutional barriers is evidenced by his efforts to have methanol accepted as a substitute fuel. Perceiving these barriers as more formidable than the task of finding technological answers to energy problems, he elaborates on the case for methanol, which is widely used in Europe and does not require large investments for research and development. As a clean-burning substitute for low-sulfur oil, methanol's only drawback as a utility fuel has been price. However, he estimates that large-scale production of methanol will make it competitive with other fuels. He also recommends pursuing solar and ocean thermal energy. As a member of EPRI's Advisory Council, his approach to legislation balances environmental concerns with an understanding of practical issues. (DCK)

Substituting freshwater: Can ocean desalination and water recycling capacities substitute for groundwater depletion in California?

Science.gov (United States)

Badiuzzaman, Pierre; McLaughlin, Eoin; McCauley, Darren

2017-12-01

While the sustainability of resource depletion is a longstanding environmental concern, wider attention has recently been given to growing water scarcity and groundwater depletion. This study seeks to test the substitutability assumption embedded in weak sustainability indicators using a case study of Californian water supply. The volume of groundwater depletion is used as a proxy for unsustainable water consumption, and defined by synthesising existing research estimates into low, medium and high depletion baselines. These are compared against projected water supply increases from ocean desalination and water recycling by 2035, to determine whether new, drought-proof water sources can substitute for currently unsustainable groundwater consumption. Results show that the maximum projected supply of new water, 2.47 million acre-feet per year (MAF/yr), is sufficient to meet low depletion estimates of 2.02 MAF/yr, but fails to come near the high depletion estimate of 3.44 MAF/yr. This does not necessarily indicate physical limitations of substitutability, but more so socio-economic limitations influenced by high comparative costs. By including capacities in demand-substitutability via urban water conservation, maximum predicted capacities reach 5.57 MAF/yr, indicating wide room for substitution. Based on these results, investment in social and institutional capital is an important factor to enhance demand-side substitutability of water and other natural resources, which has been somewhat neglected by the literature on the substitutability of natural resources. Copyright © 2017 Elsevier Ltd. All rights reserved.

Health technology assessment, value-based decision making, and innovation.

Science.gov (United States)

Henshall, Chris; Schuller, Tara

2013-10-01

Identifying treatments that offer value and value for money is becoming increasingly important, with interest in how health technology assessment (HTA) and decision makers can take appropriate account of what is of value to patients and to society, and in the relationship between innovation and assessments of value. This study summarizes points from an Health Technology Assessment International (HTAi) Policy Forum discussion, drawing on presentations, discussions among attendees, and background papers. Various perspectives on value were considered; most place patient health at the core of value. Wider elements of value comprise other benefits for: patients; caregivers; the health and social care systems; and society. Most decision-making systems seek to take account of similar elements of value, although they are assessed and combined in different ways. Judgment in decisions remains important and cannot be replaced by mathematical approaches. There was discussion of the value of innovation and of the effects of value assessments on innovation. Discussion also included moving toward "progressive health system decision making," an ongoing process whereby evidence-based decisions on use would be made at various stages in the technology lifecycle. Five actions are identified: (i) development of a general framework for the definition and assessment of value; development by HTA/coverage bodies and regulators of (ii) disease-specific guidance and (iii) further joint scientific advice for industry on demonstrating value; (iv) development of a framework for progressive licensing, usage, and reimbursement; and (v) promoting work to better adapt HTA, coverage, and procurement approaches to medical devices.

The diffusion of infrastructure dependent technologies

NARCIS (Netherlands)

Vooren, A. van der; Alkemade, F.

2010-01-01

In order to realize the transition to a more sustainable society, changes in societal subsystems such as energy and transport are necessary. Technological substitution and the diffusion of environmentally friendly technologies are envisioned to play an important role in these changes. New

Influences of IT substitutes and user experience on post-adoption user switching : An empirical investigation

NARCIS (Netherlands)

Ye, C.; Seo, D.; Desouza, K.C.; Papagari, S.; Jha, S.

2008-01-01

This study examines factors that influence individual users' post-adoption switching behavior between information technology products that are near perfect substitutes. The introduction and popularity of Mozilla Firefox Web browser provided an ideal empirical setting for this study. Drawing upon

Influences of IT substitutes and user experience on post-adoption user switching : An empirical investigation

NARCIS (Netherlands)

Ye, C.; Seo, D.; Desouza, K.C.; Papagari, S.; Jha, S.

This study examines factors that influence individual users' post-adoption switching behavior between information technology products that are near perfect substitutes. The introduction and popularity of Mozilla Firefox Web browser provided an ideal empirical setting for this study. Drawing upon

Synthesis, characterization and pharmacological evaluation of substituted phenoxy acetamide derivatives

Directory of Open Access Journals (Sweden)

Rani Priyanka

2015-01-01

Full Text Available A novel series of 2-(substituted phenoxy-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylacetamide and N-(2-bromocyclohexyl-2-(substituted phenoxyacetamide derivatives having cyclohexyl nucleus as common in both types were synthesized and assessed for their anti-inflammatory activity by a carrageenan induced rat paw oedema method, analgesic activity by Eddy’s hot plate method and antipyretic activity by brewer’s yeast induced pyrexia method. All the novel derivatives have been synthesized by the reaction of camphor and similar ketone having cyclohexane nucleus (e.g. 2-bromocyclohexanone with ammonium carbonate and formic acid resulting in the formation of aromatic amines (1a-b. These amines on further chloroacetylation with chloroacetylchloride give compounds (2a-b. Compounds (2a-b are converted to 2-(substituted phenoxy-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetamide and N-(2-bromocyclohexyl-2-(substituted phenoxyacetamide derivatives on treatment with substituted phenol. Among the series 3a-f, 3i, 3k, 3l compounds showed significant anti-inflammatory activity as compared to the standard drug diclofenac sodium and also compound 3a-f, 3h, 3j, 3k exhibit significant analgesic activity as compared to the standard drug. Compounds 3a-f and 3k showed antipyretic activity nearly to the standard drug indomethacin. Compounds 3a-f and 3k possess anti-inflammatory, analgesic and antipyretic activities near to the standard.

A novel non-toxic xylene substitute (SBO) for histology.

Science.gov (United States)

Kunhua, Wang; Chuming, Fan; Tao, Lai; Yanmei, Yang; Xin, Yang; Xiaoming, Zhang; Xuezhong, Guo; Xun, Lai

2012-01-01

Xylene has been generally used as a clearing and deparaffinizing agent in histology. Because of the potential toxic and flammable nature of xylene, its substitutes have been introduced into some laboratories. In this study, we introduced a novel, non-toxic xylene substitute (SBO), which was generated through a mixture of 86% of white oil No.2 and 14% of N-heptane. SBO had a high boiling point (188°C) and flash point (144°C) coupled with a scentless and decreased volatility. To compare the effectiveness of SBO and xylene in histology, a wide range of tissue samples from rats and human beings were processed in parallel in SBO and xylene, subjected to various staining procedures. Similar to the xylene-processed paraffin blocks, the SBO-processed counterparts were easy to section without any evidence of cell shrinkage. Assessment of the SBO-treated sections stained with hematoxylin-eosin revealed a good maintenance of cell morphology and structure, and a clear definition of the cytoplasm and the nucleus. Moreover, comparable good results were achieved between the SBO- and xylene-processed tissues in other histochemical and immunohistochemical stainings. Six-month clinical applications at one department of pathology supported the potentials of SBO as a xylene substitute. In conclusion, we suggest that SBO is a safe and efficient substitute of xylene and may probably replace xylene without losing valuable diagnostic information.

Information Technology Sector Baseline Risk Assessment

Science.gov (United States)

2009-08-01

alternative root be economically advantageous , an actor’s ability to exploit market forces and create an alternative root would be significantly improved...conduct their operations. Therefore, a loss or disruption to Internet services would not be advantageous for the desired outcomes of these syndicates.26... eCommerce Service loss or disruption [C] Traffic Redirection [C] = Undesired consequence Information Technology Sector Baseline Risk Assessment

Health technology assessment to optimize health technology utilization: using implementation initiatives and monitoring processes.

Science.gov (United States)

Frønsdal, Katrine B; Facey, Karen; Klemp, Marianne; Norderhaug, Inger Natvig; Mørland, Berit; Røttingen, John-Arne

2010-07-01

The way in which a health technology is used in any particular health system depends on the decisions and actions of a variety of stakeholders, the local culture, and context. In 2009, the HTAi Policy Forum considered how health technology assessment (HTA) could be improved to optimize the use of technologies (in terms of uptake, change in use, or disinvestment) in such complex systems. In scoping, it was agreed to focus on initiatives to implement evidence-based guidance and monitoring activities. A review identified systematic reviews of implementation initiatives and monitoring activities. A two-day deliberative workshop was held to discuss key papers, members' experiences, and collectively address key questions. This consensus paper was developed by email and finalized at a postworkshop meeting. Evidence suggests that the impact and use of HTA could be increased by ensuring timely delivery of relevant reports to clearly determined policy receptor (decision-making) points. To achieve this, the breadth of assessment, implementation initiatives such as incentives and targeted, intelligent dissemination of HTA result, needs to be considered. HTA stakeholders undertake a variety of monitoring activities, which could inform optimal use of a technology. However, the quality of these data varies and is often not submitted to an HTA. Monitoring data should be sufficiently robust so that they can be used in HTA to inform optimal use of technology. Evidence-based implementation initiatives should be developed for HTA, to better inform decision makers at all levels in a health system about the optimal use of technology.

40 CFR 721.4420 - Substituted hydroxylamine.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Substituted hydroxylamine. 721.4420... Substances § 721.4420 Substituted hydroxylamine. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified generically as substituted hydroxylamine (PMN P-84-492) is...

Research report on the trend of preventive measures against global warming by substituting CFCs; Daitai freon no chiku ondanka taisaku doko ni kansuru chosa hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

This paper reports the research results on the present state and future trend of protective measures for the ozone layer, and the trend of preventive measures against global warming by substituting CFCs such as HFC, through international conferences, meetings and lecture meetings, and literature survey. In the 8th meeting of the parties to the Montreal Protocol, it was presented that refrigerator producers in Thailand phased out CFCs from their products earlier than the schedule in cooperation with Japan. The final draft including the approval of essential use from 1997 to 2002 was reviewed, and reported to the technology/economy assessment panel. Reduction of ozone depleting substances was guided in Thailand, Indonesia and Philippines. The latest trend of substituting technologies of HCFC was surveyed, and the control trend of F-containing greenhouse effect gas emission was also surveyed through the conference of the parties of climate change in fiscal 1996. Based on the IPCC report in 1995, the emission amount of greenhouse gases of nearly 10% in contribution such as CO2, methane and fluorocarbon was arranged. R and D on destruction of CFCs was also surveyed. 35 refs., 54 figs., 32 tabs.

The political economy of the assessment of value of new health technologies.

Science.gov (United States)

Karnon, Jonathan; Edney, Laura; Afzali, Hossein

2018-04-01

Health technology assessment provides a common framework for evaluating the costs and benefits of new health technologies to inform decisions on the public funding of new pharmaceuticals and other health technologies. In Australia and England, empirical analyses of the opportunity costs of government spending on new health technologies suggest more quality adjusted life years are being forgone than are being gained by a non-trivial proportion of funded health technologies. This essay considers the relevance of available empirical estimates of opportunity costs and explores the relationship between the public funding of health technologies and broader political and economic factors. We conclude that the benefits of a general reduction in the prices paid by governments for new technologies outweigh the costs, but evidence of informed public acceptance of reduced access to new health technologies may be required to shift the current approach to assessing the value of new health technologies.

Health Monitoring System Technology Assessments: Cost Benefits Analysis

Science.gov (United States)

Kent, Renee M.; Murphy, Dennis A.

2000-01-01

The subject of sensor-based structural health monitoring is very diverse and encompasses a wide range of activities including initiatives and innovations involving the development of advanced sensor, signal processing, data analysis, and actuation and control technologies. In addition, it embraces the consideration of the availability of low-cost, high-quality contributing technologies, computational utilities, and hardware and software resources that enable the operational realization of robust health monitoring technologies. This report presents a detailed analysis of the cost benefit and other logistics and operational considerations associated with the implementation and utilization of sensor-based technologies for use in aerospace structure health monitoring. The scope of this volume is to assess the economic impact, from an end-user perspective, implementation health monitoring technologies on three structures. It specifically focuses on evaluating the impact on maintaining and supporting these structures with and without health monitoring capability.

Sample substitution can be an acceptable data-collection strategy: the case of the Belgian Health Interview Survey.

Science.gov (United States)

Demarest, Stefaan; Molenberghs, Geert; Van der Heyden, Johan; Gisle, Lydia; Van Oyen, Herman; de Waleffe, Sandrine; Van Hal, Guido

2017-11-01

Substitution of non-participating households is used in the Belgian Health Interview Survey (BHIS) as a method to obtain the predefined net sample size. Yet, possible effects of applying substitution on response rates and health estimates remain uncertain. In this article, the process of substitution with its impact on response rates and health estimates is assessed. The response rates (RR)-both at household and individual level-according to the sampling criteria were calculated for each stage of the substitution process, together with the individual accrual rate (AR). Unweighted and weighted health estimates were calculated before and after applying substitution. Of the 10,468 members of 4878 initial households, 5904 members (RRind: 56.4%) of 2707 households (RRhh: 55.5%) participated. For the three successive (matched) substitutes, the RR dropped to 45%. The composition of the net sample resembles the one of the initial samples. Applying substitution did not produce any important distorting effects on the estimates. Applying substitution leads to an increase in non-participation, but does not impact the estimations.

Mixed Waste Integrated Program: A technology assessment for mercury-containing mixed wastes

International Nuclear Information System (INIS)

Perona, J.J.; Brown, C.H.

1993-03-01

The treatment of mixed wastes must meet US Environmental Protection Agency (EPA) standards for chemically hazardous species and also must provide adequate control of the radioactive species. The US Department of Energy (DOE) Office of Technology Development established the Mixed Waste Integrated Program (MWIP) to develop mixed-waste treatment technology in support of the Mixed Low-Level Waste Program. Many DOE mixed-waste streams contain mercury. This report is an assessment of current state-of-the-art technologies for mercury separations from solids, liquids, and gases. A total of 19 technologies were assessed. This project is funded through the Chemical-Physical Technology Support Group of the MWIP

Decision Gate Process for Assessment of a NASA Technology Development Portfolio

Science.gov (United States)

Kohli, Rajiv; Fishman, Julianna L.; Hyatt, Mark J.

2012-01-01

The NASA Dust Management Project (DMP) was established to provide technologies (to Technology Readiness Level (TRL) 6) required to address adverse effects of lunar dust to humans and to exploration systems and equipment, to reduce life cycle cost and risk, and to increase the probability of sustainable and successful lunar missions. The technology portfolio of DMP consisted of different categories of technologies whose final product was either a technology solution in itself, or one that contributes toward a dust mitigation strategy for a particular application. A Decision Gate Process (DGP) was developed to assess and validate the achievement and priority of the dust mitigation technologies as the technologies progress through the development cycle. The DGP was part of continuous technology assessment and was a critical element of DMP risk management. At the core of the process were technology-specific criteria developed to measure the success of each DMP technology in attaining the technology readiness levels assigned to each decision gate. The DGP accounts for both categories of technologies and qualifies the technology progression from technology development tasks to application areas. The process provided opportunities to validate performance, as well as to identify non-performance in time to adjust resources and direction. This paper describes the overall philosophy of the DGP and the methodology for implementation for DMP, and describes the method for defining the technology evaluation criteria. The process is illustrated by example of an application to a specific DMP technology.

Technology assessment of various coal-fuel options

International Nuclear Information System (INIS)

Coenen, R.; Findling, B.; Klein-Vielhauer, S.; Nieke, E.; Paschen, H.; Tangen, H.; Wintzer, D.

1991-01-01

The technology assessment (TA) study of coal-based fuels presented in this report was performed for the Federal Ministry for Research and Technology. Its goal was to support decision-making of the Federal Ministry for Research and Technology in the field of coal conversion. Various technical options of coal liquefaction have been analyzed on the basis of hard coal as well as lignite -- direct liquefaction of coal (hydrogenation) and different possibilities of indirect liquefaction, that is the production of fuels (methanol, gasoline) by processing products of coal gasification. The TA study takes into consideration the entire technology chain from coal mining via coal conversion to the utilization of coal-based fuels in road transport. The analysis focuses on costs of the various options, overall economic effects, which include effects on employment and public budgets, and on environmental consequences compared to the use of liquid fuels derived from oil. Furthermore, requirements of infrastructure and other problems of the introduction of coal-based fuels as well as prospects for the export of technologies of direct and indirect coal liquefaction have been analyzed in the study. 14 figs., 10 tabs

BBN-Based Portfolio Risk Assessment for NASA Technology R&D Outcome

Science.gov (United States)

Geuther, Steven C.; Shih, Ann T.

2016-01-01

The NASA Aeronautics Research Mission Directorate (ARMD) vision falls into six strategic thrusts that are aimed to support the challenges of the Next Generation Air Transportation System (NextGen). In order to achieve the goals of the ARMD vision, the Airspace Operations and Safety Program (AOSP) is committed to developing and delivering new technologies. To meet the dual challenges of constrained resources and timely technology delivery, program portfolio risk assessment is critical for communication and decision-making. This paper describes how Bayesian Belief Network (BBN) is applied to assess the probability of a technology meeting the expected outcome. The network takes into account the different risk factors of technology development and implementation phases. The use of BBNs allows for all technologies of projects in a program portfolio to be separately examined and compared. In addition, the technology interaction effects are modeled through the application of object-oriented BBNs. The paper discusses the development of simplified project risk BBNs and presents various risk results. The results presented include the probability of project risks not meeting success criteria, the risk drivers under uncertainty via sensitivity analysis, and what-if analysis. Finally, the paper shows how program portfolio risk can be assessed using risk results from BBNs of projects in the portfolio.

Stiffness compatibility of coralline hydroxyapatite bone substitute under dynamic loading

Institute of Scientific and Technical Information of China (English)

无

2009-01-01

When hydroxyapatite bone substitutes are implanted in human bodies,bone tissues will grow into their porous structure,which will reinforce their strength and stiffness.The concept of mechanical com-patibility of bone substitutes implies that their mechanical properties are similar to the bone tissues around,as if they were part of the bone.The mechanical compatibility of bone substitutes includes both static and dynamic behavior,due to the mechanical properties of bone depending on the strain rate.In this study,split Hopkinson pressure bar technique(SHPB) was employed to determine the dy-namic mechanical properties of coralline hydroxyapatite,bones with and bones without organic com-ponents,and their dynamic stress-strain curves of the three materials were obtained.The mechanical effects of collagens in bone were assessed,by comparing the difference between the Young’s moduli of the three materials.As the implanted bone substitute becomes a part of bone,it can be regarded as an inclusion composite.The effective modulus of the composite was also evaluated in order to estimate its mechanical compatibility on stiffness.The evaluated result shows that the suitable porosity of HA is 0.8,which is in favor of both static and dynamic stiffness compatibility.

Technology-enabled assessment of health professions education: consensus statement and recommendations from the Ottawa 2010 Conference

DEFF Research Database (Denmark)

Amin, Zubair; Boulet, John R; Cook, David A

2011-01-01

The uptake of information and communication technologies (ICTs) in health professions education can have far-reaching consequences on assessment. The medical education community still needs to develop a deeper understanding of how technology can underpin and extend assessment practices....... This article was developed by the 2010 Ottawa Conference Consensus Group on technology-enabled assessment to guide practitioners and researchers working in this area. This article highlights the changing nature of ICTs in assessment, the importance of aligning technology-enabled assessment with local context...... and needs, the need for better evidence to support use of technologies in health profession education assessment, and a number of challenges, particularly validity threats, that need to be addressed while incorporating technology in assessment. Our recommendations are intended for all practitioners across...

Single amino acid substitution in important hemoglobinopathies does not disturb molecular function and biological process

Directory of Open Access Journals (Sweden)

Viroj Wiwanitkit

2008-06-01

Full Text Available Viroj WiwanitkitDepartment of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandAbstract: Hemoglobin is an important protein found in the red cells of many animals. In humans, the hemoglobin is mainly distributed in the red blood cell. Single amino acid substitution is the main pathogenesis of most hemoglobin disorders. Here, the author used a new gene ontology technology to predict the molecular function and biological process of four important hemoglobin disorders with single substitution. The four studied important abnormal hemoglobins (Hb with single substitution included Hb S, Hb E, Hb C, and Hb J-Baltimore. Using the GoFigure server, the molecular function and biological process in normal and abnormal hemoglobins was predicted. Compared with normal hemoglobin, all studied abnormal hemoglobins had the same function and biological process. This indicated that the overall function of oxygen transportation is not disturbed in the studied hemoglobin disorders. Clinical findings of oxygen depletion in abnormal hemoglobin should therefore be due to the other processes rather than genomics, proteomics, and expression levels.Keywords: hemoglobin, amino acid, substitution, function

Review of early assessment models of innovative medical technologies.

Science.gov (United States)

Fasterholdt, Iben; Krahn, Murray; Kidholm, Kristian; Yderstræde, Knud Bonnet; Pedersen, Kjeld Møller

2017-08-01

Hospitals increasingly make decisions regarding the early development of and investment in technologies, but a formal evaluation model for assisting hospitals early on in assessing the potential of innovative medical technologies is lacking. This article provides an overview of models for early assessment in different health organisations and discusses which models hold most promise for hospital decision makers. A scoping review of published studies between 1996 and 2015 was performed using nine databases. The following information was collected: decision context, decision problem, and a description of the early assessment model. 2362 articles were identified and 12 studies fulfilled the inclusion criteria. An additional 12 studies were identified and included in the review by searching reference lists. The majority of the 24 early assessment studies were variants of traditional cost-effectiveness analysis. Around one fourth of the studies presented an evaluation model with a broader focus than cost-effectiveness. Uncertainty was mostly handled by simple sensitivity or scenario analysis. This review shows that evaluation models using known methods assessing cost-effectiveness are most prevalent in early assessment, but seems ill-suited for early assessment in hospitals. Four models provided some usable elements for the development of a hospital-based model. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

Health technology assessment (HTA): definition, role and use in the changing healthcare environment.

Science.gov (United States)

Gallio, D; Berto, P

2007-01-01

The increasing availability of health care technology--boosted by considerable advances in areas like biotechnology, biomaterials, surgical techniques and computer technology--has accompanied burgeoning health care costs, and for this reason an increasing number of subjects (clinicians, health product makers, regulators, patients, hospitals, managers, payers, government leaders) demand for well-founded information to support decisions about development, adoption, acquisition and use of new and existing technologies. Technology assessment is a form of policy research that identifies policy issues, assesses the impact of alternative courses of action, and presents findings. This article is aimed at describing the historical development, reviewing the various definition and classifications, illustrating the purposes Fnd actors of Health Technology Assessment and its possible applications in the current healthcare scenario.

Research on simulation technology for CBRN threat assessment system. Prediction technology for atmospheric dispersion of CBRN materials

International Nuclear Information System (INIS)

Miura, Hiroaki; Yano, Masanori; Nakata, Mitsuhiro; Takeda, Masaki

2013-01-01

The technical survey is conducted on the CBRN (Chemical, Biological, Radiological and Nuclear) Threat Assessment System Simulation Technology. The dispersion property of CBRN materials is summarized, and the current simulation techniques for CBRN materials dispersion are described. The effects of advection-diffusion, sedimentation by the gravity, buoyancy and wash-out by rainfall on the dispersion property of CBRN materials should be considered in the simulation modeling. The concentration distribution of CBRN materials is predicted through the meteorological analysis, the flow analysis and the dispersion analysis, and the hazard map will be produced from that. A selection of simulation method, model, domain and number of computational grid points is necessary to perform the simulation, considering the balance between calculation cost and prediction accuracy. For construction of CBRN Threat Assessment System, it is important how to integrate the developed simulation element technologies and threat assessment technologies. (author)

An assessment of information communication technology content ...

African Journals Online (AJOL)

An assessment of information communication technology content, context and ... a- vis the upscaling of ICT in health care facilities in Nairobi and Machakos counties. ... high in all the facilities compared to levels of services operations computerised and ... for Authors · for Policy Makers · about Open Access · Journal Quality.

Cost, Time, and Risk Assessment of Different Wave Energy Converter Technology Development Trajectories: Preprint

Energy Technology Data Exchange (ETDEWEB)

Weber, Jochem W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Laird, Daniel [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Costello, Ronan [Wave Venture; Roberts, Jesse [Sandia National Laboratories; Bull, Diana [Sandia National Laboratories; Babarit, Aurelien [Ecole Centrale de Nantes; Nielsen, Kim [Ramboll; Ferreira, Claudio Bittencourt [DNV-GL; Kennedy, Ben [Wave Venture

2017-09-14

This paper presents a comparative assessment of three fundamentally different wave energy converter technology development trajectories. The three technology development trajectories are expressed and visualised as a function of technology readiness levels and technology performance levels. The assessment shows that development trajectories that initially prioritize technology readiness over technology performance are likely to require twice the development time, consume a threefold of the development cost, and are prone to a risk of technical or commercial failure of one order of magnitude higher than those development trajectories that initially prioritize technology performance over technology readiness.

Decentralized peri-urban wastewater treatment technologies assessment integrating sustainability indicators.

Science.gov (United States)

Mena-Ulecia, Karel; Hernández, Heykel Hernández

2015-01-01

Selection of treatment technologies without considering the environmental, economic and social factors associated with each geographical context risks the occurrence of negative impacts that were not properly foreseen, working against the sustainable performance of the technology. The principal aim of this study was to evaluate 12 technologies for decentralized treatment of domestic wastewater applicable to peri-urban communities using sustainability approaches and, at the same time, continuing a discussion about how to address a more integrated assessment of overall sustainability. For this, a set of 13 indicators that embody the environmental, economic and social approach for the overall sustainability assessment were used by means of a target plot diagram as a tool for integrating indicators that represent a holistic analysis of the technologies. The obtained results put forward different degrees of sustainability, which led to the selection of: septic tank+land infiltration; up-flow anaerobic reactor+high rate trickling filter and septic tank+anaerobic filter as the most sustainable and attractive technologies to be applied in peri-urban communities, according to the employed indicators.

The impact of reference pricing and extension of generic substitution on the daily cost of antipsychotic medication in Finland.

Science.gov (United States)

Koskinen, Hanna; Ahola, Elina; Saastamoinen, Leena K; Mikkola, Hennamari; Martikainen, Jaana E

2014-12-01

To assess the impact of reference pricing and extension of generic substitution on the daily cost of antipsychotic drugs in Finland during the first year after its launch. Furthermore, the additional impact of reference pricing on prior implemented generic substitution is assessed. A retrospective analysis was performed between 2006 and 2010. A segmented linear regression analysis of interrupted time series was used to estimate changes in the levels and trends in the cost of one day of treatment. Of the study drugs, clozapine belonged to generic substitution already at the start of the study period while olanzapine and quetiapine were included in generic substitution alongside with reference pricing in 2009. Risperidone was included in generic substitution in 2008, before reference pricing. A substantial decrease in the daily cost of all four antipsychotic substances was seen after one year of the implementation of reference pricing and the extension of generic substitution. The impact ranged from -29.9% to -66.3%, and it was most substantial on the daily cost of olanzapine. Also in the daily cost of risperidone a substantial decrease of -43.3% was observed. However, most of these savings, -32.6%, were generated by generic substitution which had been adopted prior. Reference pricing and the extension of generic substitution produced substantial savings on antipsychotic medication costs during the first year after its launch, but the intensity of the impact differed between active substances. Furthermore, our results suggest that the additional cost savings from reference pricing after prior implemented generic substitution, are comparatively low.

Nutrient intake disparities in the US: modeling the effect of food substitutions.

Science.gov (United States)

Conrad, Zach; Johnson, LuAnn K; Roemmich, James N; Juan, WenYen; Jahns, Lisa

2018-05-17

Diet quality among federal food assistance program participants remains low, and little research has assessed the diet quality of food insecure non-participants. Further research is needed to assess the extent to which food substitutions can improve the nutritional status of these vulnerable populations. Substituting egg dishes for other commonly consumed dishes at certain eating occasions may be an effective strategy for improving the daily nutrient intake among these groups. Eggs are rich in many important nutrients, and are low-cost and part of a wide range of cultural food menus, which are important considerations for low-income and ethnically diverse populations. To help guide the focus of targeted nutrition interventions and education campaigns for vulnerable populations, the present work begins by 1) estimating the prevalence of nutrient inadequacy among these groups, and then models the effect of consuming egg dishes instead of commonly consumed dishes at each eating occasion on 2) the prevalence of nutrient inadequacy, and 3) the mean intake of nutrients. Dietary data from 34,741 adults ≥ 20 y were acquired from the National Health and Nutrition Examination Survey, 2001-2014. Diet pattern modeling was used to substitute commonly consumed egg dishes for commonly consumed main dishes at breakfast, lunch, and dinner. National Cancer Institute usual intake methods were used to estimate the prevalence of inadequate intake of 31 nutrients pre- and post-substitution, and a novel index was used to estimate change in intake of all nutrients collectively. Substituting eggs for commonly consumed main dishes at lunch or dinner did not change total daily nutrient intake for each group (P > 0.05), but decreased the prevalence of vitamin D inadequacy by 1-4 percentage points (P diet costs, which may be an important driver of food purchasing decisions among low income individuals with limited food budgets.

Ethically sound technology? Guidelines for interactive ethical assessment of personal health monitoring.

Science.gov (United States)

Palm, Elin; Nordgren, Anders; Verweij, Marcel; Collste, Göran

2013-01-01

Novel care-technologies possess a transformational potential. Future care and support may be provided via monitoring technologies such as smart devices, sensors, actors (robots) and Information and Communication Technologies. Such technologies enable care provision outside traditional care institutions, for instance in the homes of patients. Health monitoring may become "personalized" i.e. tailored to the needs of individual care recipients' but may also alter relations between care providers and care recipents, shape and form the care environment and influence values central to health-care. Starting out from a social constructivist theory of technology, an interactive ethical assessment-model is offered. The suggested model supplements a traditional analysis based on normative ethical theory (top-down approach) with interviews including relevant stakeholders (a bottom-up approach). This method has been piloted by small-scale interviews encircling stakeholder perspectives on three emerging technologies: (1) Careousel, a smart medicine-management device, (2) Robot Giraff, an interactive and mobile communication-device and (3) I-Care, a care-software that combines alarm and register system. By incorporating stakeholder perspectives into the analysis, the interactive ethical assessment model provides a richer understanding of the impact of PHM-technologies on ethical values than a traditional top-down model. If the assessment is conducted before the technology has reached the market - preferably in close interaction with developers and users - ethically sound technologies may be obtained.

An Assessment of Petroleum Technology Development Fund (Ptdf ...

African Journals Online (AJOL)

An Assessment of Petroleum Technology Development Fund (Ptdf) ... and other related literature were utilized to elicit information for the research. ... industry and that some of those trained lack the technical know-how to manage the refineries.

Blindness enhances auditory obstacle circumvention: Assessing echolocation, sensory substitution, and visual-based navigation.

Science.gov (United States)

Kolarik, Andrew J; Scarfe, Amy C; Moore, Brian C J; Pardhan, Shahina

2017-01-01

Performance for an obstacle circumvention task was assessed under conditions of visual, auditory only (using echolocation) and tactile (using a sensory substitution device, SSD) guidance. A Vicon motion capture system was used to measure human movement kinematics objectively. Ten normally sighted participants, 8 blind non-echolocators, and 1 blind expert echolocator navigated around a 0.6 x 2 m obstacle that was varied in position across trials, at the midline of the participant or 25 cm to the right or left. Although visual guidance was the most effective, participants successfully circumvented the obstacle in the majority of trials under auditory or SSD guidance. Using audition, blind non-echolocators navigated more effectively than blindfolded sighted individuals with fewer collisions, lower movement times, fewer velocity corrections and greater obstacle detection ranges. The blind expert echolocator displayed performance similar to or better than that for the other groups using audition, but was comparable to that for the other groups using the SSD. The generally better performance of blind than of sighted participants is consistent with the perceptual enhancement hypothesis that individuals with severe visual deficits develop improved auditory abilities to compensate for visual loss, here shown by faster, more fluid, and more accurate navigation around obstacles using sound.

Blindness enhances auditory obstacle circumvention: Assessing echolocation, sensory substitution, and visual-based navigation.

Directory of Open Access Journals (Sweden)

Andrew J Kolarik

Full Text Available Performance for an obstacle circumvention task was assessed under conditions of visual, auditory only (using echolocation and tactile (using a sensory substitution device, SSD guidance. A Vicon motion capture system was used to measure human movement kinematics objectively. Ten normally sighted participants, 8 blind non-echolocators, and 1 blind expert echolocator navigated around a 0.6 x 2 m obstacle that was varied in position across trials, at the midline of the participant or 25 cm to the right or left. Although visual guidance was the most effective, participants successfully circumvented the obstacle in the majority of trials under auditory or SSD guidance. Using audition, blind non-echolocators navigated more effectively than blindfolded sighted individuals with fewer collisions, lower movement times, fewer velocity corrections and greater obstacle detection ranges. The blind expert echolocator displayed performance similar to or better than that for the other groups using audition, but was comparable to that for the other groups using the SSD. The generally better performance of blind than of sighted participants is consistent with the perceptual enhancement hypothesis that individuals with severe visual deficits develop improved auditory abilities to compensate for visual loss, here shown by faster, more fluid, and more accurate navigation around obstacles using sound.

European network for health technology assessment, EUnetHTA: planning, development, and implementation of a sustainable European network for health technology assessment

DEFF Research Database (Denmark)

Kristensen, Finn Børlum; Mäkelä, Marjukka; Neikter, Susanna Allgurin

2009-01-01

OBJECTIVES: The European network on Health Technology Assessment (EUnetHTA) aimed to produce tangible and practical results to be used in the various phases of health technology assessment and to establish a framework and processes to support this. This article presents the background, objectives......, and organization of EUnetHTA, which involved a total of sixty-four partner organizations. METHODS: Establishing an effective and sustainable structure for a transnational network involved many managerial, policy, and methodological tools, according to the objective of each task or Work Package. Transparency...... the use of HTA at national and regional levels. Responsiveness to political developments in Europe should be balanced with maintaining a high level of ambition to promote independent, evidence-based information and well-tested tools for best practice based on a strong network of HTA institutions....

Institutionalizing Emerging Technology Assessment Process into National Incident Response

Science.gov (United States)

2013-10-01

mechanical methods, devices, and products, including oil sensors, booms, skimmers, decontamination , and waste minimization technologies...handling). • Alternative Oil Spill Response Technologies (in situ burning , dispersants, etc.). • Oil Spill Damage Assessment and Restoration. The TETs...deaths of eleven crewmembers and a subsequent uncontrolled oil spill that tested the government’s ability to respond to a spill of this magnitude as

Substitutes for School Nurses in Illinois

Science.gov (United States)

Vollinger, Linda Jeno; Bergren, Martha Dewey; Belmonte-Mann, Frances

2011-01-01

The purpose of this descriptive study was to explore utilization of nurse substitutes in the school setting in Illinois. The literature described personnel who staff the school health office in the absence of the school nurse and the barriers to obtaining nurse substitutes. There were no empirical studies conducted on school nurse substitutes in…

The substitutive effect of biofuels on fossil fuels in the lower and higher crude oil price periods

Energy Technology Data Exchange (ETDEWEB)

Chang, Ting-Huan [Energy and Environment Research Laboratories, Industrial Technology Research Institute, Hsinchu County 310 (China); Department of Banking and Finance, Tamkang University, No.151, Ying-Chuan Road, Taipei County 251 (China); Su, Hsin-Mei [Department of Banking and Finance, Tamkang University, No.151, Ying-Chuan Road, Taipei County 251 (China)

2010-07-15

Various biofuels, including bioethanol and biodiesel are technologically being considered replacements for fossil fuels, such as the conventional gasoline and diesel. This paper aims to measure whether economic substitutability can be generated during periods of higher and/or lower prices of crude oil. The empirical results of the bivariate EGARCH model prove that this substitutive effect was occurred during the higher crude oil price period due to the significant price spillover effects from crude oil futures to corn and soybean futures, indicating that the increase in food prices can be attributed to more consumption of biofuels. We suggest more extensive research in the search for fuel alternatives from inedible feedstock such as pongamia, jojoba, jatropha, especially the 2nd generation biofuel technologies such as algae-based biofuels. (author)

The substitutive effect of biofuels on fossil fuels in the lower and higher crude oil price periods

International Nuclear Information System (INIS)

Chang, Ting-Huan; Su, Hsin-Mei

2010-01-01

Various biofuels, including bioethanol and biodiesel are technologically being considered replacements for fossil fuels, such as the conventional gasoline and diesel. This paper aims to measure whether economic substitutability can be generated during periods of higher and/or lower prices of crude oil. The empirical results of the bivariate EGARCH model prove that this substitutive effect was occurred during the higher crude oil price period due to the significant price spillover effects from crude oil futures to corn and soybean futures, indicating that the increase in food prices can be attributed to more consumption of biofuels. We suggest more extensive research in the search for fuel alternatives from inedible feedstock such as pongamia, jojoba, jatropha, especially the 2nd generation biofuel technologies such as algae-based biofuels. (author)

Prospective Technology Assessment of Synthetic Biology: Fundamental and Propaedeutic Reflections in Order to Enable an Early Assessment.

Science.gov (United States)

Schmidt, Jan Cornelius

2016-08-01

Synthetic biology is regarded as one of the key technosciences of the future. The goal of this paper is to present some fundamental considerations to enable procedures of a technology assessment (TA) of synthetic biology. To accomplish such an early "upstream" assessment of a not yet fully developed technology, a special type of TA will be considered: Prospective TA (ProTA). At the center of ProTA are the analysis and the framing of "synthetic biology," including a characterization and assessment of the technological core. The thesis is that if there is any differentia specifica giving substance to the umbrella term "synthetic biology," it is the idea of harnessing self-organization for engineering purposes. To underline that we are likely experiencing an epochal break in the ontology of technoscientific systems, this new type of technology is called "late-modern technology." -I start this paper by analyzing the three most common visions of synthetic biology. Then I argue that one particular vision deserves more attention because it underlies the others: the vision of self-organization. I discuss the inherent limits of this new type of late-modern technology in the attempt to control and monitor possible risk issues. I refer to Hans Jonas' ethics and his early anticipation of the risks of a novel type of technology. I end by drawing conclusions for the approach of ProTA towards an early societal shaping of synthetic biology.

Modeling competitive substitution in a polyelectrolyte complex

International Nuclear Information System (INIS)

Peng, B.; Muthukumar, M.

2015-01-01

We have simulated the invasion of a polyelectrolyte complex made of a polycation chain and a polyanion chain, by another longer polyanion chain, using the coarse-grained united atom model for the chains and the Langevin dynamics methodology. Our simulations reveal many intricate details of the substitution reaction in terms of conformational changes of the chains and competition between the invading chain and the chain being displaced for the common complementary chain. We show that the invading chain is required to be sufficiently longer than the chain being displaced for effecting the substitution. Yet, having the invading chain to be longer than a certain threshold value does not reduce the substitution time much further. While most of the simulations were carried out in salt-free conditions, we show that presence of salt facilitates the substitution reaction and reduces the substitution time. Analysis of our data shows that the dominant driving force for the substitution process involving polyelectrolytes lies in the release of counterions during the substitution

Exchange of researchers of oil substituting energies in EU countries; EU shokoku no sekiyu daitai energy kenkyusha koryu jigyo

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

In order to further promote smoother introduction of oil substituting energies and development of new energies and energy saving technologies, it was intended to exchange and acquire items of information effective to learn the current state and policy trends on research and development of new energies and energy conservation in the EU countries who are the industrialized countries like Japan and enthusiastic in developing oil substituting energies. Therefore, exchange of researchers was carried out with an objective to contribute to research and development of oil substituting energies by deepening mutual understanding on the development efforts and forming efficient cooperative relationship. The researchers who visited Japan are Dr. Robert Durand (France) and Prof. and Dr. Bruno Scrosati (Italy). Dr. Durand has a great knowledge about fuel cells and storage batteries, and Dr. Scrosati about electrolytes and lithium batteries. Both gentlemen have visited the Agency of Industrial Science and Technology and the Agency of Natural Resources and Energy of the Ministry of International Trade and Industry, NEDO, Toshiba, Sony, Sanyo Electric, Japan Storage Battery, Matsushita Battery Industry, the Industrial Technology Research Institute of Osaka, and Kansai Electric Power Company. Views and information were exchanged and a number of good results were rewarded.

Practice parameters facilitating adoption of advanced technologies for enhancing neuropsychological assessment paradigms.

Science.gov (United States)

Parsons, Thomas D; McMahan, Timothy; Kane, Robert

2018-01-01

Clinical neuropsychologists have long underutilized computer technologies for neuropsychological assessment. Given the rapid advances in technology (e.g. virtual reality; tablets; iPhones) and the increased accessibility in the past decade, there is an on-going need to identify optimal specifications for advanced technologies while minimizing potential sources of error. Herein, we discuss concerns raised by a joint American Academy of Clinical Neuropsychology/National Academy of Neuropsychology position paper. Moreover, we proffer parameters for the development and use of advanced technologies in neuropsychological assessments. We aim to first describe software and hardware configurations that can impact a computerized neuropsychological assessment. This is followed by a description of best practices for developers and practicing neuropsychologists to minimize error in neuropsychological assessments using advanced technologies. We also discuss the relevance of weighing potential computer error in light of possible errors associated with traditional testing. Throughout there is an emphasis on the need for developers to provide bench test results for their software's performance on various devices and minimum specifications (documented in manuals) for the hardware (e.g. computer, monitor, input devices) in the neuropsychologist's practice. Advances in computerized assessment platforms offer both opportunities and challenges. The challenges can appear daunting but are a manageable and require informed consumers who can appreciate the issues and ask pertinent questions in evaluating their options.

Harnessing Technology to Assess Oral Communication in Business English

Science.gov (United States)

Levy, Tal; Gertler, Hedy

2015-01-01

Assessing oral skills in relatively large Business English classes seems a most formidable task for any teacher. How does one make sure to get multiple and valid assessments of each student? This action research paper provides supporting evidence for the correlation between the use of technology and students' engagement. This was achieved by…

Is it health information technology? : Task complexity and work substitution

NARCIS (Netherlands)

Medina Palomino, Hector; Rutkowski, Anne; Verhulst, Matthijs

2015-01-01

New technology is making it possible to replace professions built on complex knowledge, e.g. medicine. In our exploratory research we examined how Information Technologies might be replacing some of the tasks formerly processed by physician anesthesiologists (MDAs). Data (N=1178) were collected at a

Substitutional analysis

CERN Document Server

Rutherford, Daniel Edwin

2013-01-01

Classic monograph, suitable for advanced undergraduates and graduate students. Topics include calculus of permutations and tableaux, semi-normal representation, orthogonal and natural representations, group characters, and substitutional equations. 1968 edition.

Aryl substitution of pentacenes

Directory of Open Access Journals (Sweden)

Andreas R. Waterloo

2014-07-01

Full Text Available A series of 11 new pentacene derivatives has been synthesized, with unsymmetrical substitution based on a trialkylsilylethynyl group at the 6-position and various aryl groups appended to the 13-position. The electronic and physical properties of the new pentacene chromophores have been analyzed by UV–vis spectroscopy (solution and thin films, thermoanalytical methods (DSC and TGA, cyclic voltammetry, as well as X-ray crystallography (for 8 derivatives. X-ray crystallography has been specifically used to study the influence of unsymmetrical substitution on the solid-state packing of the pentacene derivatives. The obtained results add to our ability to better predict substitution patterns that might be helpful for designing new semiconductors for use in solid-state devices.

Aryl substitution of pentacenes

Science.gov (United States)

Waterloo, Andreas R; Sale, Anna-Chiara; Lehnherr, Dan; Hampel, Frank

2014-01-01

Summary A series of 11 new pentacene derivatives has been synthesized, with unsymmetrical substitution based on a trialkylsilylethynyl group at the 6-position and various aryl groups appended to the 13-position. The electronic and physical properties of the new pentacene chromophores have been analyzed by UV–vis spectroscopy (solution and thin films), thermoanalytical methods (DSC and TGA), cyclic voltammetry, as well as X-ray crystallography (for 8 derivatives). X-ray crystallography has been specifically used to study the influence of unsymmetrical substitution on the solid-state packing of the pentacene derivatives. The obtained results add to our ability to better predict substitution patterns that might be helpful for designing new semiconductors for use in solid-state devices. PMID:25161729

The impact of health technology assessment reports on decision making in Austria.

Science.gov (United States)

Zechmeister, Ingrid; Schumacher, Ines

2012-01-01

Health technology assessment (HTA) was established in Austria in the 1990s and, since then, it has gained considerable importance. In this study, we aim to analyze whether the HTA reports that have been produced at the Institute for Technology Assessment (ITA) and at the Ludwig Boltzmann Institute for HTA (LBI-HTA) have had an impact on decision making within the Austrian health care system. We selected all reports that were intended for supporting (i) reimbursement/investment or (ii) disinvestment decisions. Eleven full HTA reports and fifty-eight rapid assessments fulfilled the inclusion criteria. We used interview data and administrative data on volumes, tariffs and expenditure of products/services to analyze whether and how reports were in reality used in decision making and what the consequences for health care expenditure and resource distribution have been. Five full HTA reports and fifty-six rapid technology assessments were used for reimbursement decisions. Four full HTA reports and two rapid assessments were used for disinvestment decisions and resulted in reduced volumes and expenditure. Two full HTA reports showed no impact on decision making. Impact was most evident for hospital technologies. HTA has played some role in reducing volumes of over-supplied hospital technologies, resulting in reduced expenditure for several hospital providers. Additionally, it has been increasingly included in prospective planning and reimbursement decisions of late, indicating re-distribution of resources toward evidence-based technologies. However, further factors may have influenced the decisions, and the impact could be considerably increased by systematically incorporating HTA into the decision-making process in Austria.

Human factors assessments of D and D technologies

International Nuclear Information System (INIS)

Carpenter, C.P.; Evans, T.T.; McCabe, B.

2000-01-01

On April 2, 1997, the US Secretary of Energy directed the US Assistant Secretary of Environmental Management and of Safety and Health to require field input of appropriate data to ensure that safety and health considerations were properly addressed in the Accelerating Cleanup: Focus on 2006 Plan. The US Department of Energy (DOE) field managers have committed to the Secretary that they will fully implement integrated safety management systems (ISMSs) at their respective sites by the end of fiscal year 1999. The Secretary has further directed that headquarters safety and health guidance be developed to support consistent and comprehensive project baseline summaries from the field. The Secretary has committed to institutionalizing ISMS as an integral component of the way the DOE conducts its business. The Defense Nuclear Facilities Safety Board continues to oversee and closely monitor the DOE's commitment to the safety and health of its workers. The DOE is committed to a management system approach to ensure that work is performed in a manner that protects the worker, public, and environment. The Deactivation and Decommissioning Focus Area (DDFA) is actively addressing the need to incorporate environmental safety and health (ES and H) considerations in developing technologies. The DDFA is partnered with the Operating Engineers National Hazmat Program (OENHP) to evaluate the ES and H considerations of the innovative and improved decontamination and decommissioning technologies. Part of the implementation of the ES and H work practices in the field is through a cooperative agreement between the National Energy Technology Laboratory (NETL) and the OENHP. The objective of this program is to establish an International Environmental Technology and Training Center to conduct human factors assessments and protocols on environmental technologies. The intent of the human factors assessments is to enhance the effectiveness and efficiency of the technologies and to enhance

Computational study of cation substitutions in apatites

International Nuclear Information System (INIS)

Tamm, Toomas; Peld, Merike

2006-01-01

Density-functional theory plane-wave modeling of fluor- and hydroxyapatites has been performed, where one or two calcium ions per unit cell were replaced with cadmium or zinc cations. It was found that cadmium ions favor Ca(1) positions in fluorapatites and Ca(2) positions in hydroxyapatites, in agreement with experiment. A similar pattern is predicted for zinc substitutions. In the doubly substituted cases, where only hydroxyapatites were modeled, a preference for the substituting ions to be located in Ca(2) position was also observed. Displacement of the hydroxide ions from their symmetrical positions on the hexagonal axis can be used to explain the preferred configurations of substituting ions around the axis. -- Deformation of the hydroxide ion chain due to substitutions around the ion channel in substituted hydroxyapatites

China’s Energy Transition in the Power and Transport Sectors from a Substitution Perspective

Directory of Open Access Journals (Sweden)

Shangfeng Han

2017-04-01

Full Text Available Facing heavy air pollution, China needs to transition to a clean and sustainable energy system, especially in the power and transport sectors, which contribute the highest greenhouse gas (GHG emissions. The core of an energy transition is energy substitution and energy technology improvement. In this paper, we forecast the levelized cost of electricity (LCOE for power generation in 2030 in China. Cost-emission effectiveness of the substitution between new energy vehicles and conventional vehicles is also calculated in this study. The results indicate that solar photovoltaic (PV and wind power will be cost comparative in the future. New energy vehicles are more expensive than conventional vehicles due to their higher manufacturer suggested retail price (MSRP. The cost-emission effectiveness of the substitution between new energy vehicles and conventional vehicles would be $96.7/ton or $114.8/ton. Gasoline prices, taxes, and vehicle insurance will be good directions for policy implementation after the ending of subsidies.

Technology Assessment for Powertrain Components Final Report CRADA No. TC-1124-95

Energy Technology Data Exchange (ETDEWEB)

Tokarz, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gough, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-10-19

LLNL utilized its defense technology assessment methodologies in combination with its capabilities in the energy; manufacturing, and transportation technologies to demonstrate a methodology that synthesized available but incomplete information on advanced automotive technologies into a comprehensive framework.

Currency substitution in Eastern Europe

NARCIS (Netherlands)

van Aarle, B.; Budina, N.

1995-01-01

Monetary instability during the transition process from a command economy to a market economy has induced a considerable increase in currency substitution in Eastern Europe. Currency substitution itself affects monetary stability since it reduces the stability of velocity. This paper investigates

Health technology assessment: research trends and future priorities in Europe.

Science.gov (United States)

Nielsen, Camilla Palmhøj; Funch, Tina Maria; Kristensen, Finn Børlum

2011-07-01

To provide an overview of health services research related to health technology assessment (HTA) and to identify research priorities from a European perspective. Several methods were used: systematic review of articles indexed with the MeSH term 'technology assessment' in PubMed from February 1999-2009; online survey among experts; and conference workshop discussions. Research activity in HTA varies considerably across Europe. The research was categorised into six areas: (1) the breadth of analysis in HTA (such as economic, organizational and social aspects); (2) HTA products developed to meet the needs of policy-makers (such as horizon scanning, mini-HTA, and core HTA); (3) handling life-cycle perspectives in relation to technologies; (4) topics that challenge existing methods and for which HTA should be developed to address the themes more comprehensively (such as public health interventions and organizational interventions); (5) development of HTA capacity and programmes; and (6) links between policy and HTA. An online survey showed that the three areas that were given priority were the relationship between HTA and policy-making (71%), the impact of HTA (62%) and incorporating patient aspects in HTA (50%). Policy-makers highlighted HTA and innovation processes as their main research priority (42%). Areas that the systematic review identified as future priorities include issues within the six existing research areas such as disinvestment, developing evidence for new technologies, assessing the wider effects of technology use, and determining how HTA affects decision-making. In addition, relative effectiveness and individualized treatments are areas of growing interest. The research priorities identified are important for obtaining high quality and cost-effective health care in Europe. Managing the introduction, use and phasing out of technologies challenges health services throughout Europe, and these processes need to be improved to successfully manage future

Substitute Energy Carriers from Refinement of Coal using HTR-Module

International Nuclear Information System (INIS)

Barnert, Heiko; Kugeler, Kurt; Will, Michael

2014-01-01

There is a revival of coal refinement in the world: a recent press article in Germany titled “The Renaissance of Coal Refinement”. It reports about a large number of conventional plans and plants for coal refinement in many countries in the world, and in particular in China. Nuclear energy can be of assistance, in particular the High Temperature Reactor-Module, because it offers all needed process energies. The status of the research, development, and demonstration, RDD, of technology is summarized, in particular of the former programs in Germany: The primary energy carriers were hard coal and lignite. The envisaged products were: Substitute Natural Gas, SNG, for the gas market, Hydrogen, H2, for a future H2-market, e.g. for airplane traffic, Liquid Fuels, as Substitute Gasoline, or as Energy Alcohol, e.g. Methanol CH3OH, in mixture with higher alcohols, for the car traffic and for home heating. (author)

Substitution of saturated fat in processed meat products: a review.

Science.gov (United States)

Ospina-E, J C; Sierra-C, A; Ochoa, O; Pérez-Álvarez, J A; Fernández-López, J

2012-01-01

The food industry is increasingly directing its efforts to produce and commercialize functional foods where the reduction or even elimination of saturated fat is an important goal. This situation arises from the concern of many institutions and individuals worldwide on the growth of non-transmissible diseases, particularly cardiovascular ones. This article presents a revision of the most important research carried out on processed meat products production and looks at the topic from two principal points of view: the nutritional and technological function of fat and the way in which it is gradually being replaced in the above-mentioned products. Many ingredients have been used to substitute fat but while the results concerning the nutritional composition of the final products are generally acceptable, the sensory aspects are not completely solved. This review emphasizes the use of plastic fats because they allow the highest fat substitution levels during its process and consumption without affecting the product behavior.

Chitosan Dermal Substitute and Chitosan Skin Substitute Contribute to Accelerated Full-Thickness Wound Healing in Irradiated Rats

Directory of Open Access Journals (Sweden)

Abu Bakar Mohd Hilmi

2013-01-01

Full Text Available Wounds with full-thickness skin loss are commonly managed by skin grafting. In the absence of a graft, reepithelialization is imperfect and leads to increased scar formation. Biomaterials can alter wound healing so that it produces more regenerative tissue and fewer scars. This current study use the new chitosan based biomaterial in full-thickness wound with impaired healing on rat model. Wounds were evaluated after being treated with a chitosan dermal substitute, a chitosan skin substitute, or duoderm CGF. Wounds treated with the chitosan skin substitute showed the most re-epithelialization (33.2 ± 2.8%, longest epithelial tongue (1.62 ± 0.13 mm, and shortest migratory tongue distance (7.11 ± 0.25 mm. The scar size of wounds treated with the chitosan dermal substitute (0.13 ± 0.02 cm and chitosan skin substitute (0.16 ± 0.05 cm were significantly decreased (P<0.05 compared with duoderm (0.45 ± 0.11 cm. Human leukocyte antigen (HLA expression on days 7, 14, and 21 revealed the presence of human hair follicle stem cells and fibroblasts that were incorporated into and surviving in the irradiated wound. We have proven that a chitosan dermal substitute and chitosan skin substitute are suitable for wound healing in full-thickness wounds that are impaired due to radiation.

Development and assessment of closure technology for liquid-waste disposal sites

International Nuclear Information System (INIS)

Phillips, S.J.; Relyea, J.F.; Seitz, R.R.; Cammann, J.W.

1990-01-01

Discharge of low-level liquid wastes into soils was practiced previously at the Hanford Site. Technologies for long-term confinement of subsurface contaminants are needed. Additionally, methods are needed to assess the effectiveness of confinement technologies in remediating potentially diverse environmental conditions. Recently developed site remediation systems and assessment methods for in situ stabilization and isolation of radioactive and other contaminants within and below low-level liquid-waste disposal structures are summarized

Study design for concurrent development, assessment, and implementation of new diagnostic imaging technology

NARCIS (Netherlands)

M.G.M. Hunink (Myriam); G.P. Krestin (Gabriel)

2002-01-01

textabstractWith current constraints on health care resources and emphasis on value for money, new diagnostic imaging technologies must be assessed and their value demonstrated. The state of the art in the field of diagnostic imaging technology assessment advocates a hierarchical

Phonological analysis of substitution errors of patients with apraxia of speech

Directory of Open Access Journals (Sweden)

Maysa Luchesi Cera

Full Text Available Abstract The literature on apraxia of speech describes the types and characteristics of phonological errors in this disorder. In general, phonemes affected by errors are described, but the distinctive features involved have not yet been investigated. Objective: To analyze the features involved in substitution errors produced by Brazilian-Portuguese speakers with apraxia of speech. Methods: 20 adults with apraxia of speech were assessed. Phonological analysis of the distinctive features involved in substitution type errors was carried out using the protocol for the evaluation of verbal and non-verbal apraxia. Results: The most affected features were: voiced, continuant, high, anterior, coronal, posterior. Moreover, the mean of the substitutions of marked to markedness features was statistically greater than the markedness to marked features. Conclusions: This study contributes toward a better characterization of the phonological errors found in apraxia of speech, thereby helping to diagnose communication disorders and the selection criteria of phonemes for rehabilitation in these patients.

Technology and Economic Assessment of Innovative Field Drainage Technologies in Denmark

DEFF Research Database (Denmark)

Gachango, Florence Gathoni

Intensive agricultural production in most parts of the world especially in the more developed countries continues to mount pressure on water resources thereby threatening the quality of life in the aquatic ecosystems. With stringent standards such as those stipulated in the European Union Water...... Framework Directive (EU WFD), introduced to address the water quality problem the situation calls for solutions that would reconcile these two conflicting issues. “End-of-pipe” filter technologies that would disconnect agricultural drainage pathway before it gets to the aquatic environment have been...... proposed as appropriate solutions to this problem in the Danish context. The feasibility of these technologies with regards to their cost-effectiveness in nutrient mitigation, farmers’ adoption behavior, and environmental policy implementation is assessed in this thesis. The thesis comprises of four papers...

Substitution between cars within the household

DEFF Research Database (Denmark)

De Borger, Bruno; Mulalic, Ismir; Rouwendal, Jan

2016-01-01

In this paper we study the demand for car kilometres in two-car households, focusing on the substitution between cars of different fuel efficiency in response to fuel price changes. We use a large sample of detailed Danish data on two-car households to estimate – for each car owned by the household...... – own and cross-price effects of increases in fuel costs per kilometre. The empirical results show that failure to capture substitution between cars within the household can result in substantial misspecification biases. Ignoring substitution, the basic model yielded fuel price elasticities of 0.......98 and 1.41 for the primary and secondary cars, respectively. Accounting for substitution effects, these figures reduce to, respectively, 0.32 and 0.45. Consistent with substitution behaviour, we find that the fuel price elasticity of fuel demand exceeds the elasticity of kilometre demands with respect...

Elasticity of Substitution and Antidumping Measures

DEFF Research Database (Denmark)

Drud Hansen, Jørgen; Meinen, Philipp; Nielsen, Jørgen Ulff-Møller

Abstract This paper analyzes the role of the elasticity of substitution for anti-dumping decisions across countries. In monopolistic competition models with cost heterogeneous firms across countries, price differences vary inversely with the elasticity of substitution. Anti-dumping duties should...... therefore also vary inversely with the elasticity of substitution at least for countries which have a strong focus on prices in the determination of their anti-dumping measures. We test this for ten countries from 1990 to 2009 using data on anti-dumping from Chad Bown (2010) and US-data at 8-digit level...... in our empirical investigation support the predicted role of the elasticity of substitution as we find a significant negative relation between the elasticity of substitution and the final anti-dumping duties for the ‘lesser duty rule’ group of countries. The countries which do not follow the ‘lesser duty...

A needs assessment for mobile technology use in medical education

OpenAIRE

Shahrzad Vafa; Diane E. Chico

2013-01-01

Objectives: This study investigated how medical students perceived mobile technology as a component of their learning experience and identified barriers to the use of mobile technology in education. Methods: An anonymous survey developed by EDUCAUSE was distributed to 1000 first year medical students (M1s) at two separate medical schools during three consecutive academic years, 2010 to 2013. The 25-item questionnaire assessed student use of mobile devices, student interest in mobile technolog...

Membrane separation systems---A research and development needs assessment

Energy Technology Data Exchange (ETDEWEB)

Baker, R.W. (Membrane Technology and Research, Inc., Menlo Park, CA (USA)); Cussler, E.L. (Minnesota Univ., Minneapolis, MN (USA). Dept. of Chemical Engineering and Materials Science); Eykamp, W. (California Univ., Berkeley, CA (USA)); Koros, W.J. (Texas Univ., Austin, TX (USA)); Riley, R.L. (Separation Systems Technology, San Diego, CA (USA)); Strathmann, H. (Fraunhofer-Institut fuer Grenzflaech

1990-03-01

Membrane based separation technology, a relative newcomer on the separations scene, has demonstrated the potential of saving enormous amounts of energy in the processing industries if substituted for conventional separation systems. Over 1 quad annually, out of 2.6, can possibly be saved in liquid-to-gas separations, alone, if membrane separation systems gain wider acceptance, according to a recent DOE/OIP (DOE/NBM-80027730 (1986)) study. In recent years great strides have been made in the field and offer even greater energy savings in the future when substituted for other conventional separation techniques such as distillation, evaporation, filtration, sedimentation, and absorption. An assessment was conducted by a group of six internationally known membrane separations experts who examined the worldwide status of research in the seven major membrane areas. This encompassed four mature technology areas: reverse osmosis, micorfiltration, ultrafiltration, and electrodialysis; two developing areas: gas separation and and pervaporation; and one emerging technology: facilitated transport. Particular attention was paid to identifying the innovative processes currently emerging, and even further improvements which could gain wider acceptance for the more mature membrane technology. The topics that were pointed out as having the greatest research emphasis are pervaporation for organic-organic separations; gas separation; micorfiltration; an oxidant-resistant reverse osmosis membrane; and a fouling-resistant ultrafiltration membrane. 35 refs., 6 figs., 22 tabs.

IMPLEMENTATION OF HEALTH TECHNOLOGY ASSESSMENT WORK IN A HOSPITAL IN KAZAKHSTAN.

Science.gov (United States)

Kosherbayeva, Lyazzat; Hailey, David; Kurakbaev, Kural; Tsoy, Aleksey; Zhuzzhanov, Ormanbek; Donbay, Abilay; Kumar, Ainur; Nadyrov, Kamalzhan

2016-01-01

The aim of this study was to implement health technology assessment (HA) in the First General City Hospital in Astana, Kazakhstan. We organized trainings to familiarize hospital staff with the purpose and details of HTA. An HTA committee was established, with representation from hospital physicians and managers, and criteria for prioritization of health technologies determined. Clinical departments of the hospital were asked to prepare applications for new technologies for their services. The HTA committee reviewed five applications and selected a technology from one of these, on single incision laparoscopic surgery (SILS), for assessment. A short HTA report on SILS was prepared, covering its safety, clinical effectiveness, and cost effectiveness. The report was used to support a request to the Department of Health for additional funding to implement this technology within the hospital. This funding was approved and SILS was established in several hospital departments. This successful initial experience with HTA has paved the way for its routine use by the hospital for informing decisions on the procurement and use of new health technologies.

Biological background of dermal substitutes

NARCIS (Netherlands)

van der Veen, V. C.; van der Wal, M.B.; van Leeuwen, M.C.; Ulrich, M.; Middelkoop, E.

2010-01-01

Dermal substitutes are of major importance in treating full thickness skin defects, both in acute and chronic wounds. In this review we will outline specific requirements of three classes of dermal substitutes:-natural biological materials, with a more or less intact extracellular matrix

Double dividend effectiveness of energy tax policies and the elasticity of substitution: A CGE appraisal

International Nuclear Information System (INIS)

Sancho, Ferran

2010-01-01

There is a considerable body of literature that has studied whether or not an adequately designed tax swap, whereby an ecotax is levied and some other tax is reduced while keeping government income constant, may achieve a so-called double dividend, that is, an increase in environmental quality and an increase in overall efficiency. Arguments in favor and against are abundant. Our position is that the issue should be empirically studied starting from an actual, non-optimal tax system structure and by way of checking the responsiveness of equilibria to revenue neutral tax regimes under alternate scenarios regarding technological substitution. With the use of a CGE model, we find that the most critical elasticity for achieving a double dividend is the substitution elasticity between labor and capital whereas the elasticity that would generate the highest reduction in carbon dioxide emissions is the substitution elasticity among energy goods.

Double dividend effectiveness of energy tax policies and the elasticity of substitution. A CGE appraisal

Energy Technology Data Exchange (ETDEWEB)

Sancho, Ferran [Departament d' Economia, Universitat Autonoma de Barcelona, 08193-Bellaterra (Spain)

2010-06-15

There is a considerable body of literature that has studied whether or not an adequately designed tax swap, whereby an ecotax is levied and some other tax is reduced while keeping government income constant, may achieve a so-called double dividend, that is, an increase in environmental quality and an increase in overall efficiency. Arguments in favor and against are abundant. Our position is that the issue should be empirically studied starting from an actual, non-optimal tax system structure and by way of checking the responsiveness of equilibria to revenue neutral tax regimes under alternate scenarios regarding technological substitution. With the use of a CGE model, we find that the most critical elasticity for achieving a double dividend is the substitution elasticity between labor and capital whereas the elasticity that would generate the highest reduction in carbon dioxide emissions is the substitution elasticity among energy goods. (author)

Shedding light on solar technologies-A techno-economic assessment and its policy implications

International Nuclear Information System (INIS)

Peters, Michael; Schmidt, Tobias S.; Wiederkehr, David; Schneider, Malte

2011-01-01

Solar power technologies will have to become a major pillar in the world's future energy system to combat climate change and resource depletion. However, it is unclear which solar technology is and will prove most viable. Therefore, a comprehensive comparative assessment of solar technologies along the key quantitative and qualitative competitiveness criteria is needed. Based on a literature review and detailed techno-economic modeling for 2010 and 2020 in five locations, we provide such an assessment for the three currently leading large-scale solar technologies. We show that today these technologies cannot yet compete with conventional forms of power generation but approach competitiveness around 2020 in favorable locations. Furthermore, from a global perspective we find that none of the solar technologies emerges as a clear winner and that cost of storing energy differs by technology and can change the order of competitiveness in some instances. Importantly, the competitiveness of the different technologies varies considerably across locations due to differences in, e.g., solar resource and discount rates. Based on this analysis, we discuss policy implications with regard to fostering the diffusion of solar technologies while increasing the efficiency of policy support through an adequate geographical allocation of solar technologies. - Highlights: → We conduct a comprehensive comparative assessment of solar technologies (CSP/PV). → While solar technologies approach competitiveness in 2020, no clear winner emerges. → Solar resource and discount rate heavily impact competitiveness of solar technologies. → Adequate geographical allocation of solar technologies increases policy efficiency. → Focus on key cost down levers and strategic co-benefits of solar technologies needed.

Novel sensing technology in fall risk assessment in older adults: a systematic review.

Science.gov (United States)

Sun, Ruopeng; Sosnoff, Jacob J

2018-01-16

Falls are a major health problem for older adults with significant physical and psychological consequences. A first step of successful fall prevention is to identify those at risk of falling. Recent advancement in sensing technology offers the possibility of objective, low-cost and easy-to-implement fall risk assessment. The objective of this systematic review is to assess the current state of sensing technology on providing objective fall risk assessment in older adults. A systematic review was conducted in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement (PRISMA). Twenty-two studies out of 855 articles were systematically identified and included in this review. Pertinent methodological features (sensing technique, assessment activities, outcome variables, and fall discrimination/prediction models) were extracted from each article. Four major sensing technologies (inertial sensors, video/depth camera, pressure sensing platform and laser sensing) were reported to provide accurate fall risk diagnostic in older adults. Steady state walking, static/dynamic balance, and functional mobility were used as the assessment activity. A diverse range of diagnostic accuracy across studies (47.9% - 100%) were reported, due to variation in measured kinematic/kinetic parameters and modelling techniques. A wide range of sensor technologies have been utilized in fall risk assessment in older adults. Overall, these devices have the potential to provide an accurate, inexpensive, and easy-to-implement fall risk assessment. However, the variation in measured parameters, assessment tools, sensor sites, movement tasks, and modelling techniques, precludes a firm conclusion on their ability to predict future falls. Future work is needed to determine a clinical meaningful and easy to interpret fall risk diagnosis utilizing sensing technology. Additionally, the gap between functional evaluation and user experience to technology should be addressed.

Achievement report for fiscal 1976 on Sunshine Program. Technology assessment of hydrogen energy technologies III; 1976 nendo suiso energy gijutsu no technology assessment. 3

Energy Technology Data Exchange (ETDEWEB)

NONE

1977-03-31

This report contains the ultimate results of the 3-year research endeavor on 'Technology assessment of hydrogen energy technologies.' The scientists engaged in the project express their impressions at the conclusion of the research, stating: 'In the development of hydrogen energy technologies, what is the most important at the present stage is to define the formation of the energy more clearly - in what shape or at what place - so that various activities in this connection will be organized.' They say also: 'Although the type of research effort of looking into technological possibilities is quite important naturally, yet such should been carried out with a sense of purpose which is definite and concrete.' Before what are stated above may be complied with, of course, systems for development have to be arranged allowing the scientists to act in the above-suggested way. This report consists of a general discussion part and an itemized discussion part. The former summarizes the intention, aim, premise, contents, findings, opinions, etc., concerning the research work; and the latter carries a gist of the 'Hydrogen energy system concept (draft)' which constitutes the foundation on which the above-mentioned details are discussed in the former. (NEDO)

Integrated assessment of bioelectricity technology options

International Nuclear Information System (INIS)

Thornley, Patricia; Upham, Paul; Huang, Ye; Rezvani, Sina; Brammer, John; Rogers, John

2009-01-01

Power generation from biomass is a sustainable energy technology which can contribute to substantial reductions in greenhouse gas emissions, but with greater potential for environmental, economic and social impacts than most other renewable energy technologies. It is important therefore in assessing bioenergy systems to take account of not only technical, but also environmental, economic and social parameters on a common basis. This work addresses the challenge of analysing, quantifying and comparing these factors for bioenergy power generation systems. A life-cycle approach is used to analyse the technical, environmental, economic and social impacts of entire bioelectricity systems, with a number of life-cycle indicators as outputs to facilitate cross-comparison. The results show that similar greenhouse gas savings are achieved with the wide variety of technologies and scales studied, but land-use efficiency of greenhouse gas savings and specific airborne emissions varied substantially. Also, while specific investment costs and electricity costs vary substantially from one system to another the number of jobs created per unit of electricity delivered remains roughly constant. Recorded views of stakeholders illustrate that diverging priorities exist for different stakeholder groups and this will influence appropriate choice of bioenergy systems for different applications

Substitution of wastes for fuels and raw materials in high-temperature processes; Substitution von Brennstoffen und Rohstoffen durch Abfaelle in Hochtemperaturprozessen

Energy Technology Data Exchange (ETDEWEB)

Scholz, R. [Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany). Inst. fuer Energieverfahrenstechnik; Beckmann, M. [Clausthaler Umwelttechnik-Institut GmbH (CUTEC), Clausthal-Zellerfeld (Germany)

1998-09-01

The physical recycling and energy conversion of wastes has for a long time been a topic of discussion. Some of the most interesting questions in this connection concern specific applications such as the co-combustion of sewage sludge in power plants, substitution of plastic wastes for primary fuels in burning processes in the cement industry etc. This paper also undertakes a comparative study of different applications, giving additional consideration to the state of the art in thermal waste treatment. Different processes can of course only be compared by taking the entirety of expenditures on additives and auxiliary energy into account and assuming equal side constraints for all processes. A further requirement is that the waste materials` specific properties that are relevant to the application in question have to be taken into account. This concerns in particular the effects of the substitution of waste-derived fuels (secondary fuels) for primary fuels on, for example, heat transfer conditions during the combustion process, flow conditions, and the resultant temperature distribution, transport of feedstock, and specific energy expenditure. Secondary fuels must be suited for substitution in various respects, e.g. in their material properties, and their combustion and thermal behaviour. The present paper deals in particular with the requirements on wastes as substitutes for primary fuels with regard to combustion and thermal behaviour. For this purpose it briefly discusses some important aspects of heat transfer in firing plants and industrial furnaces. An important criterion in assessing fuel substitution is the energy exchange ratio, which expresses value of the substitute fuel relative to that of the primary fuel and should be duly considered when making comparative studies. Focussing on aspects of process engineering the paper also deals exemplarily with the influence of fuel substitution on, e.g. furnace temperature, exhaust gas quantities etc. in clinker

Multi-objective assessment of rural electrification in remote areas with poverty considerations

International Nuclear Information System (INIS)

Silva, Diego; Nakata, Toshihiko

2009-01-01

Rural electrification with renewable energy technologies (RETs) offers several benefits to remote areas where diesel generation is unsuitable due to fuel supply constraints. Such benefits include environmental and social aspects, which are linked to energy access and poverty reduction in less-favored areas of developing countries. In this case, multi-objective methods are suitable tools for planning in rural areas. In this study, assessment of rural electrification with renewable energy systems is conducted by means of goal programming towards fuel substitution. The approach showed that, in the Non-Interconnected Zones of Colombia, substitution of traditional biomass with an electrification scheme using renewable energy sources provides significant environmental benefits, measured as land use and avoided emissions, as well as higher employment generation rates than diesel generation schemes. Nevertheless, fuel substitution is constrained by the elevated cost of electricity compared to traditional biomass, which raises households' energy expenditures between twofold to five times higher values. The present approach, yet wide in scope, is still limited for quantifying the impact of energy access improvements on poverty reduction, as well as for the assessment of energy system's technical feasibility.

Summary of 2017 NASA Workshop on Assessment of Advanced Battery Technologies for Aerospace Applications

Science.gov (United States)

Misra, Ajay

2018-01-01

A workshop on assessment of battery technologies for future aerospace applications was held in Cleveland, OH on August 16-17. The focus of the workshop, hosted by NASA GRC, was to assess (1) the battery needs for future aerospace missions, (2) the state of battery technology and projected technology advances, and (3) the need for additional investments for future aerospace missions. The workshop had 109 attendees that included internationally recognized technology leaders from academia and national laboratories, high level executives from government and industry, small businesses, and startup companies. A significant portion of the workshop was focused on batteries for electrified aircraft. The presentation will summarize the finding on the state of battery technologies for electrified aircraft and will include assessment of current state of battery technology, gaps in battery technology for application in electrified aircraft, and recommended technology development options for meeting near-term and long-term needs of electrified aircraft.

Effects of saliva substitutes on oral status in patients with Type 2 diabetes.

Science.gov (United States)

Montaldo, L; Montaldo, P; Papa, A; Caramico, N; Toro, G

2010-11-01

To assess oral status in a sample of Type 2 diabetic patients before and after therapy with saliva substitutes and oral status in a control group of diabetic patients who were not given saliva substitutes. Salivary flow rate was determined in 134 patients (mean age 47.9 ± 2.9 years) with Type 2 diabetes. Mean salivary rate was significantly low compared with a healthy control group. The sample of 134 patients was randomly divided into two groups of 67 people each. One group was given immunologically active salivary substitutes for 6 months, the other group was given nothing. Each patient of the two groups underwent a dental and periodontal examination at the beginning of the study and 6 months later. As regards carious teeth and teeth loss, there was no statistical difference between the first group after 6 months of treatment with salivary substitutes and the control group (P>0.01). Salivary substitutes did not significantly reduce the periodontal disease (P>0.01). In the group treated with salivary substitutes, after 6 months of therapy, the average dental plaque index decreased from 2.3 ± 0.73 to 1.6 ± 0.56, patients with gingivitis decreased from 66 to 43% and patients with positive yeast counts decreased from 60 to 37%. These differences were statistically significant (Pdiabetes, in the case of hyposalivation, a therapy with immunologically active saliva substitutes can be of help in reducing the amount of plaque, gingivitis and positive yeast counts. © 2010 The Authors. Diabetic Medicine © 2010 Diabetes UK.

Substitution of peat, fertiliser and manure by compost in hobby gardening: user surveys and case studies.

Science.gov (United States)

Andersen, Jacob K; Christensen, Thomas H; Scheutz, Charlotte

2010-12-01

Four user surveys were performed at recycle centres (RCs) in the Municipalities of Aarhus and Copenhagen, Denmark, to get general information on compost use and to examine the substitution of peat, fertiliser and manure by compost in hobby gardening. The average driving distance between the users' households and the RCs was found to be 4.3 km and the average amount of compost picked up was estimated at 800 kg per compost user per year. The application layer of the compost varied (between 1 and 50 cm) depending on the type of use. The estimated substitution (given as a fraction of the compost users that substitute peat, fertiliser and manure with compost) was 22% for peat, 12% for fertiliser and 7% for manure (41% in total) from the survey in Aarhus (n=74). The estimate from the survey in Copenhagen (n=1832) was 19% for peat, 24% for fertiliser and 15% for manure (58% in total). This is the first time, to the authors' knowledge, that the substitution of peat, fertiliser and manure with compost has been assessed for application in hobby gardening. Six case studies were performed as home visits in addition to the Aarhus surveys. From the user surveys and the case studies it was obvious that the total substitution of peat, fertiliser and manure was not 100%, as is often assumed when assigning environmental credits to compost. It was more likely around 50% and thus there is great potential for improvement. It was indicated that compost was used for a lot of purposes in hobby gardening. Apart from substitution of peat, fertiliser and manure, compost was used to improve soil quality and as a filling material (as a substitute for soil). Benefits from these types of application are, however, difficult to assess and thereby quantify. Copyright © 2010 Elsevier Ltd. All rights reserved.

Application of computational algorithms to assess the functionality of non-synonymous substitutions in MHC DRB gene of Nigerian goats

Directory of Open Access Journals (Sweden)

Yakubu Abdulmojeed

2017-01-01

Full Text Available The Major Histocompatibility Complex (MHC contains highly variable multi-gene families, which play a key role in the adaptive immune response within vertebrates. Among the Capra MHC class II genes, the expressed DRB locus is highly polymorphic, particularly in exon 2, which encodes the antigen-binding site. Models of variable non-synonymous/synonymous rate ratios among sites may provide important insights into functional constraints at different amino acid sites and may be used to detect sites under positive selection. Many non-synonymous single nucleotide polymorphisms (nsSNPs at the DRB locus in goats are suspected to impact protein function. This study, therefore, aimed at comparing the efficiency of six computational approaches to predict the likelihood of a particular non-synonymous (amino acid change coding SNP to cause a functional impact on the protein. This involved the use of PANTHER, SNAP, SIFT, PolyPhen-2, PROVEAN and nsSNPAnalyzer bioinformatics analytical tools in detecting harmful and beneficial effects at H57G, Y89R, V104D and Y112I substitutions in the peptide binding region of the DRB gene of Nigerian goats. The results from PANTHER analysis revealed that H57G, Y89R and Y112I substitutions (Pdeleterious= 0.113, 0.204 and 0.472, respectively were beneficial; while that of V104D was deleterious (Pdeleterious= 0.756, an indication that it was non-neutral. As regards the SNAP approach, H57G and Y89R substitutions were returned neutral with expected accuracy of 53 and 69%, respectively while V104D and Y112I substitutions were harmful. H57G and Y89R substitutions were also found harmless in the SIFT analysis. However, only H57G (PROVEAN and V104D (nsSNPAnalyzer amino acid substitutions were found to be beneficial. Interestingly, the predicted 3D structures of both native and mutant DRB protein appeared similar as validated by Ramachandran plots. The consensus reached by PANTHER, SNAP, SIFT and PolyPhen-2 approaches on the neutrality

Risk analysis and technology assessment in support of technology development: Putting responsible innovation in practice in a case study for nanotechnology.

Science.gov (United States)

van Wezel, Annemarie P; van Lente, Harro; van de Sandt, Johannes Jm; Bouwmeester, Hans; Vandeberg, Rens Lj; Sips, Adrienne Jam

2018-01-01

Governments invest in "key enabling technologies," such as nanotechnology, to solve societal challenges and boost the economy. At the same time, governmental agencies demand risk reduction to prohibit any often unknown adverse effects, and industrial parties demand smart approaches to reduce uncertainties. Responsible research and innovation (RRI) is therefore a central theme in policy making. Risk analysis and technology assessment, together referred to as "RATA," can provide a basis to assess human, environmental, and societal risks of new technological developments during the various stages of technological development. This assessment can help both governmental authorities and innovative industry to move forward in a sustainable manner. Here we describe the developed procedures and products and our experiences to bring RATA in practice within a large Dutch nanotechnology consortium. This is an example of how to put responsible innovation in practice as an integrated part of a research program, how to increase awareness of RATA, and how to help technology developers perform and use RATA. Integr Environ Assess Manag 2018;14:9-16. © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC). © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

Developing an Instrument for Assessing Students' Concepts of the Nature of Technology

Science.gov (United States)

Liou, Pey-Yan

2015-01-01

Background: The nature of technology has been rarely discussed despite the fact that technology plays an essential role in modern society. It is important to discuss students' concepts of the nature of technology, and further to advance their technological literacy and adaptation to modern society. There is a need to assess high school students'…

Substitution models for overlapping technologies - an application to fast reactor deployment

International Nuclear Information System (INIS)

Lehtinen, R.; Silvennoinen, P.; Vira, J.

1982-01-01

In this paper market penetration models are discussed in the context of interacting technologies. An increased confidence credit is proposed for a technology that can draw on other overlapping technologies. The model is also reduced to a numerically tractable form. As an application, scenarios of fast reactor deployment are derived under different assumptions on the uranium and fast reactor investment costs and by varying model parameters for the penetration of fusion and solar technologies. The market share of fast reactors in electricity generation is expected to lie between zero and 40 per cent in 2050 depending on the market parameters. (orig.) [de

Foods for Special Dietary Needs: Non-dairy Plant-based Milk Substitutes and Fermented Dairy-type Products.

Science.gov (United States)

Mäkinen, Outi Elina; Wanhalinna, Viivi; Zannini, Emanuele; Arendt, Elke Karin

2016-01-01

A growing number of consumers opt for plant-based milk substitutes for medical reasons or as a lifestyle choice. Medical reasons include lactose intolerance, with a worldwide prevalence of 75%, and cow's milk allergy. Also, in countries where mammal milk is scarce and expensive, plant milk substitutes serve as a more affordable option. However, many of these products have sensory characteristics objectionable to the mainstream western palate. Technologically, plant milk substitutes are suspensions of dissolved and disintegrated plant material in water, resembling cow's milk in appearance. They are manufactured by extracting the plant material in water, separating the liquid, and formulating the final product. Homogenization and thermal treatments are necessary to improve the suspension and microbial stabilities of commercial products that can be consumed as such or be further processed into fermented dairy-type products. The nutritional properties depend on the plant source, processing, and fortification. As some products have extremely low protein and calcium contents, consumer awareness is important when plant milk substitutes are used to replace cow's milk in the diet, e.g. in the case of dairy intolerances. If formulated into palatable and nutritionally adequate products, plant-based substitutes can offer a sustainable alternative to dairy products.

Strengthening of bridges by post-tensioning using monostrands in substituted cable ducts

Science.gov (United States)

Klusáček, Ladislav; Svoboda, Adam

2017-09-01

Post-tensioning is suitable, reliable and durable method of strengthening existing engineering structures, especially bridges. The high efficiency of post-tensioning can be seen in many applications throughout the world. In this paper the method is extended by a structural system of substituted cable ducts, which allows for significantly widening application of prestressing so it’s convenient mostly for application on beam bridges or slab bridges (built in years 1920 - 1960). The method of substituted cable ducts is based on theoretical knowledge and technical procedures, which were made possible through the development in prestressing systems, particularly the development of prestressing tendons (monostrands) and encased anchorages, as well as progress in drilling technology. This technique is highly recommended due to minimization of interventions into the constructions, unseen method of cable arrangement and hence the absence of impact on appearance, which is appreciated not only in case of valuable historical structures but also in general. It is possible to summarise that posttensioning by monostrands in substituted cable ducts is a highly effective method of strengthening existing bridges in order to increase their load capacities in terms of current traffic load and to extend their service life.

Radiation detection technology assessment program (RADTAP)

International Nuclear Information System (INIS)

Smith, D.E.

1998-01-01

The U.S. Customs Service and the U.S. Department of Energy (DOE) conducted a technical and operational assessment of gamma ray radiation detection equipment during the period May 5-16, 1997 at a testing facility in North Carolina. The effort was entitled, ''Radiation Detection Technology Assessment Program (RADTAP)'', and was conducted for the purpose of assessing the applicability, sensitivity and robustness of a diverse suite of gamma ray detection and identification equipment for possible use by Customs and other law enforcement agencies. Thirteen companies entered 25 instruments into the assessment program. All detection equipment entered had to exhibit a minimum sensitivity of 20 micro-R per hour (background included) from a Cesium-137 point source. Isotope identifying spectrometers entered were man portable and operable at room temperature with read-out that could be interpreted by non-technical personnel. Radioactive sources used in the assessment included special nuclear material, industrial and health isotopes. Evaluators included Customs inspectors and technical experts from DOE and Customs. No conclusions or recommendations were issued based on the quantitative and qualitative test results, however, the results of the program provided law enforcement agencies with the necessary data to select equipment that best meets their operational needs and budgets. (author)

Assessment of material and technical resources of crop production technologies

Directory of Open Access Journals (Sweden)

V. M. Beylis

2017-01-01

Full Text Available The author explains the general principles of influence of the material and technical resources (MTR on performance and efficiency of the main technological operations in crop production. Various technologies from the point of view of MTR expenses were estimated. The general tendencies in development of crop production technologies were revealed. The distribution of costs of materials and equipment to perform a variety of agricultural activities was determined. Cost indicators should be a guide in the search of innovative technological processes and working elements of agricultural machins. The greatest values of expenses of work, fuel, metal, and also, money where found. The concepts allowing to provide costs production reduction were formulated. To achieve the maximum productivity with the minimum expenses, the perspective calculations shoul be based on «progressive» agrotechnologies. When determining progressive agrotechnology it is necessary on reasonable grounds to approach indicators of crop productivity in various agrozones and regions of the country. For an assessment of efficiency of MTR by crop production and ensuring decrease in resource intensity of agricultural products by search and use of essentially new technologies for energy saving when performing agricultural operations, an integrated percentage indicator of comparison of progressive technologies with the applied ones was developed. MTR at application of new progressive crop production technologies by integrated percentage index were estimated. This indicator can be used for definition of efficiency of MTR. Application of the offered technique will promote an effective assessment of MTR, decrease in resource intensity by search and developments of essentially new technologies of performance of operations in crop production.

Radiographic Comparison of Bovine Bone Substitute Alone versus Bovine Bone Substitute and Simvastatin for Human Maxillary Sinus Augmentation

Directory of Open Access Journals (Sweden)

Amir Ali Reza Rasouli Ghahroudi

2018-01-01

Full Text Available Objectives: The aim of this study was to compare the efficacy of bovine bone substitute (Compact Bone B. ® alone versus bovine bone substitute and simvastatin for human maxillary sinus augmentation.Materials and Methods: This study was conducted on 16 sinuses in eight patients. Radiographic assessments were done preoperatively (T0, immediately (T1 and at nine months after sinus grafting (T2. Alveolar bone height and density were assessed on cone beam computed tomography (CBCT scans using Planmeca Romexis™ Imaging Software 2.2.Results: The change in alveolar bone height and density between T0, T1 and T2 was significant in both groups. Alveolar bone height (h0, h1, h2 and vertical height of the grafted bone (g1, g2 in three lines (anterior, middle and posterior were not significantly different between groups. The grafted bone height shrinkage (% in the anterior, middle and posterior limits of the augmented area were not significantly different between groups. The existing alveolar and grafted bone density increased significantly in both groups between T1 and T2, except for the existing alveolar bone density in the control group. There were no statistically significant differences between the alveolar bone density values obtained in TI and T2 between groups, except for the existing alveolar bone density at T1.Conclusions: This study did not show any significant positive effect for simvastatin in maxillary sinus augmentation based on radiographic examination.

A Self-Assessment Framework for Inclusive Schools Supporting Assistive Technology Users.

Science.gov (United States)

Hoogerwerf, Evert-Jan; Solander-Gross, Andrea; Mavrou, Katerina; Traina, Ivan; Hersh, Marion

2017-01-01

In order to support schools to assess their performance in supporting children with disabilities in their ICT and ICT-AT needs, a self-assessment framework was developed by a task force of partners and associate partners of the ENTELIS project. The self-assessment tool aims to help educational establishments that welcome learners with disabilities to assess their current outcomes and to plan improvements in supporting these students in increasing digital literacy and developing digital skills. This includes the use of mainstream Information and Communication Technology (ICT) and specially designed digital Assistive Technologies (ICT-AT). This can only successfully happen if schools fully embrace an inclusive approach to education. In this paper the authors describe the development of the framework and the further steps for its use.

Substitution in recreation choice behavior

Science.gov (United States)

George L. Peterson; Daniel J. Stynes; Donald H. Rosenthal; John F. Dwyer

1985-01-01

This review discusses concepts and theories of substitution in recreation choice. It brings together the literature of recreation research, psychology, geography, economics, and transportation. Parallel and complementary developments need integration into an improved theory of substitution. Recreation decision behavior is characterized as a nested or sequential choice...

Why Does Trigonometric Substitution Work?

Science.gov (United States)

Cunningham, Daniel W.

2018-01-01

Modern calculus textbooks carefully illustrate how to perform integration by trigonometric substitution. Unfortunately, most of these books do not adequately justify this powerful technique of integration. In this article, we present an accessible proof that establishes the validity of integration by trigonometric substitution. The proof offers…

Enhanced bioactivity, biocompatibility and mechanical behavior of strontium substituted bioactive glasses.

Science.gov (United States)

Arepalli, Sampath Kumar; Tripathi, Himanshu; Hira, Sumit Kumar; Manna, Partha Pratim; Pyare, Ram; S P Singh

2016-12-01

Strontium contained biomaterials have been reported as a potential bioactive material for bone regeneration, as it reduces bone resorption and stimulates bone formation. In the present investigation, the bioactive glasses were designed to partially substitute SrO for SiO2 in Na2O-CaO-SrO-P2O5-SiO2 system. This work demonstrates that the substitution of SrO for SiO2 has got significant benefit than substitution for CaO in the bioactive glass. Bioactivity was assessed by the immersion of the samples in simulated body fluid for different intervals. The formation of hydroxy carbonate apatite layer was identified by X-ray diffractometry, scanning electron microscopy (SEM) and energy dispersive spectroscopy. The elastic modulus of the bioactive glasses was measured and found to increase with increasing SrO for SiO2. The blood compatibility of the samples was evaluated. In vitro cell culture studies of the samples were performed using human osteosarcoma U2-OS cell lines and found a significant improvement in cell viability and proliferation. The investigation showed enhancement in bioactivity, mechanical and biological properties of the strontia substituted for silica in glasses. Thus, these bioactive glasses would be highly potential for bone regeneration. Copyright © 2016 Elsevier B.V. All rights reserved.

Evolving provider payment models and patient access to innovative medical technology.

Science.gov (United States)

Long, Genia; Mortimer, Richard; Sanzenbacher, Geoffrey

2014-12-01

Abstract Objective: To investigate the evolving use and expected impact of pay-for-performance (P4P) and risk-based provider reimbursement on patient access to innovative medical technology. Structured interviews with leading private payers representing over 110 million commercially-insured lives exploring current and planned use of P4P provider payment models, evidence requirements for technology assessment and new technology coverage, and the evolving relationship between the two topics. Respondents reported rapid increases in the use of P4P and risk-sharing programs, with roughly half of commercial lives affected 3 years ago, just under two-thirds today, and an expected three-quarters in 3 years. All reported well-established systems for evaluating new technology coverage. Five of nine reported becoming more selective in the past 3 years in approving new technologies; four anticipated that in the next 3 years there will be a higher evidence requirement for new technology access. Similarly, four expected it will become more difficult for clinically appropriate but costly technologies to gain coverage. All reported planning to rely more on these types of provider payment incentives to control costs, but didn't see them as a substitute for payer technology reviews and coverage limitations; they each have a role to play. Interviews limited to nine leading payers with models in place; self-reported data. Likely implications include a more uncertain payment environment for providers, and indirectly for innovative medical technology and future investment, greater reliance on quality and financial metrics, and increased evidence requirements for favorable coverage and utilization decisions. Increasing provider financial risk may challenge the traditional technology adoption paradigm, where payers assumed a 'gatekeeping' role and providers a countervailing patient advocacy role with regard to access to new technology. Increased provider financial risk may result in an

Substituted Indoleacetic Acids Tested in Tissue Cultures

DEFF Research Database (Denmark)

Engvild, Kjeld Christensen

1978-01-01

Monochloro substituted IAA inhibited shoot induction in tobacco tissue cultures about as much as IAA. Dichloro substituted IAA inhibited shoot formation less. Other substituted IAA except 5-fluoro- and 5-bromoindole-3-acetic acid were less active than IAA. Callus growth was quite variable...

Mapping of health technology assessment in selected countries

NARCIS (Netherlands)

Oortwijn, W.; Broos, P.; Vondeling, Hindrik; Banta, D.; Todorova, L.

2013-01-01

Objectives: The aim of this study was to develop and apply an instrument to map the level of health technology assessment (HTA) development at country level in selected countries. We examined middle-income countries (Argentina, Brazil, India, Indonesia, Malaysia, Mexico, and Russia) and countries

Can unenhanced multiparametric MRI substitute gadolinium-enhanced MRI in the characterization of vertebral marrow infiltrative lesions?

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Dalia Z. Zidan

2014-06-01

Conclusion: Unenhanced-multiparametric MRI is compatible with gadolinium-enhanced MRI in reliable characterization of marrow infiltrative lesions. The routine MRI protocol of cancer patients should be altered to accommodate the evolving MRI technology and cost effectively substitute the need for a gadolinium enhanced scan.

Improvement of methods of evaluation of investment projects in the context of import substitution

Directory of Open Access Journals (Sweden)

Kuvshinov M.S.

2017-01-01

Full Text Available Due to the imposition of sanctions, based more on geopolitical interests, there were additional essential restrictions on sources of external credits, use of import raw materials and technologies, possibilities of attraction to work of the qualified employees which do not have the Russian nationality, participation in the international technology and scientific projects. At similar restrictions of different resources investment decisions are made extremely carefully, and especially careful and reasonable efficiency evaluation of the investments is required. Traditionally used techniques of efficiency evaluation of investment projects not fully consider strategic interests of owners of industrial enterprises and investors. Decrease in risks requires higher quality of project evaluation. In this work the method of multi-level consistently complex integral assessment of investment projects on an indicator of the integral indicator of their efficiency implementing consecutive selection of investment projects from a portfolio on essential indicators of commercial effectiveness, efficiency of production business activities, a financial state and productivity of activity is provided. The developed method of a complex assessment of investment projects is implemented for practical application by the software product allowing to create on the basis of economic-mathematical modeling specific recommendations in economic practice of industrial enterprises during the developing and implementation of investment strategies. The conclusion that for the Russian economy in the conditions of import substitution accounting of all set of interests of investors and owners of the enterprises provides development and implementation of reasonable investment strategies is drawn.

Currency Substitution and Inflation in Peru Currency Substitution and Inflation in Peru

OpenAIRE

Liliana Rojas-Suarez

1992-01-01

This paper shows that there is a long-run relationship between the expected rate of depreciation in the black-market-exchange rate and the ratio of domestic to foreign money in Peru: that is, the hypothesis of currency substitution can explain the behavior of real holdings of money in Peru. The paper also shows that, while, the importance of currency substitution as a transmission mechanism through which domestic policies affected the dynamics of inflation was relatively small during a period...

Energy and the environment: Technology assessment and policy options

International Nuclear Information System (INIS)

Silveira, M.P.W.

1990-01-01

While the energy crisis of the 1970s stimulated technological innovation in developed countries, it often had the opposite effect in the third world. However, developing countries can be considered to have two types of energy systems: ''connected'' and ''disconnected''. The connected system is affected by changes in the price of commercial energy, but the disconnected system is usually rural and remote. Commercial forms of energy may be needed in the disconnected system, but they are largely unavailable. In some of the developing countries, new energy technologies have therefore been developed which adapt traditional technologies still existing in the disconnected sector. In this article some of the work of the United National Centre for Science and Technology for Development is described. Through its ATAS (Advance Technology Alert System) programme, international and regional workshops are held to discuss policy questions arising in regard to new technologies and developments. Workshops have been held in Moscow on new energy technologies in the industry subsystem (connected), in Guatemala City on new energy technologies and the disconnected system, and in Ottawa on new energy technologies, transportation and development. Initial assessments made by or through these workshops are outlined here. A fourth workshop will be held in June 1990 in Saarbrucken on energy technologies and climate change. (author). 3 figs

Electronic Engineering Technology Program Exit Examination as an ABET and Self-Assessment Tool

Science.gov (United States)

Thomas, Gary; Darayan, Shahryar

2018-01-01

Every engineering, computing, and engineering technology program accredited by the Accreditation Board for Engineering and Technology (ABET) has formulated many and varied self-assessment methods. Methods used to assess a program for ABET accreditation and continuous improvement are for keeping programs current with academic and industrial…

How do general practitioners, pharmacists and patients evaluate the substitution system for prescription in Denmark?

DEFF Research Database (Denmark)

Rubak, Sune; Andersen, Marie-Louise Elkjær; Mainz, Jan

2002-01-01

Aim/Objectives: Evaluation of how the substitution system has been implemented, how it was assessed by the general practitioners (GPs), pharmacists (PHs) and patients, and clarification of benefits and problems related to the system. Methods: The study was based on specific question-naires to GPs....... How do general practitioners, pharmacists and patients evaluate the substitution system for prescription in Denmark?. Available from: http://www.researchgate.net/publication/243131968_How_do_general_practitioners_pharmacists...

The Morishima Gross elasticity of substitution

OpenAIRE

Blackorby, Charles; Primont, Daniel; Russell, R. Robert

2007-01-01

We show that the Hotelling-Lau elasticity of substitution, an extension of the Allen-Uzawa elasticity to allow for optimal output-quantity (or utility) responses to changes in factor prices, inherits all of the failings of the Allen-Uzawa elasticity identified by Blackorby and Russell [1989 AER]. An analogous extension of the Morishima elasticity of substitution to allow for output quantity changes preserves the salient properties of the original Hicksian notion of elasticity of substitution.

Sustainability Assessment of Electricity Generation Technologies in Egypt Using Multi-Criteria Decision Analysis

Directory of Open Access Journals (Sweden)

Mostafa Shaaban

2018-05-01

Full Text Available Future electricity planning necessitates a thorough multi-faceted analysis of the available technologies in order to secure the energy supply for coming generations. To cope with worldwide concerns over sustainable development and meet the growing demands of electricity we assess the future potential technologies in Egypt through covering their technical, economic, environmental and social aspects. In this study we fill the gap of a lacking sustainability assessment of energy systems in Egypt where most of the studies focus mainly on the economic and technical aspects of planning future installation of power plants in Egypt. Furthermore, we include the stakeholder preferences of the indicators in the energy sector into our assessment. Moreover, we perform a sensitivity analysis through single dimension assessment scenarios of the technologies as well as a sustainable scenario with equal preferences of all dimensions of the sustainability. We employ two multi-criteria decision analysis (MCDA methodologies: the analytical hierarchy process for weighing the assessment criteria, and the weighted sum method for generating a general integrated sustainability index for each technology. The study investigates seven technologies: coal, natural gas, wind, concentrated solar power, photovoltaics, biomass and nuclear. The results reveal a perfect matching between the ranking of the technologies by the stakeholders and the sustainable scenario showing the highest ranking for natural gas and the lowest for nuclear and coal. There is a strong potential for renewable energy technologies to invade the electricity market in Egypt where they achieve the second ranking after natural gas. The Monte-Carlo approach gives photovoltaics a higher ranking over concentrated solar power as compared to the sample data ranking. The study concludes the importance of a multi-dimensional evaluation of the technologies while considering the preferences of the stakeholders in

HVDC power transmission technology assessment

Energy Technology Data Exchange (ETDEWEB)

Hauth, R.L.; Tatro, P.J.; Railing, B.D. [New England Power Service Co., Westborough, MA (United States); Johnson, B.K.; Stewart, J.R. [Power Technologies, Inc., Schenectady, NY (United States); Fink, J.L.

1997-04-01

The purpose of this study was to develop an assessment of the national utility system`s needs for electric transmission during the period 1995-2020 that could be met by future reduced-cost HVDC systems. The assessment was to include an economic evaluation of HVDC as a means for meeting those needs as well as a comparison with competing technologies such as ac transmission with and without Flexible AC Transmission System (FACTS) controllers. The role of force commutated dc converters was to be assumed where appropriate. The assessment begins by identifying the general needs for transmission in the U.S. in the context of a future deregulated power industry. The possible roles for direct current transmission are then postulated in terms of representative scenarios. A few of the scenarios are illustrated with the help of actual U.S. system examples. non-traditional applications as well as traditional applications such as long lines and asynchronous interconnections are discussed. The classical ``break-even distance`` concept for comparing HVDC and ac lines is used to assess the selected scenarios. The impact of reduced-cost converters is reflected in terms of the break-even distance. This report presents a comprehensive review of the functional benefits of HVDC transmission and updated cost data for both ac and dc system components. It also provides some provocative thoughts on how direct current transmission might be applied to better utilize and expand our nation`s increasingly stressed transmission assets.

Life-cycle assessment of selected management options for air pollution control residues from waste incineration.

Science.gov (United States)

Fruergaard, Thilde; Hyks, Jiri; Astrup, Thomas

2010-09-15

Based on available technology and emission data seven selected management options for air-pollution-control (APC) residues from waste incineration were evaluated by life-cycle assessment (LCA) using the EASEWASTE model. Scenarios were evaluated with respect to both non-toxicity impact categories (e.g. global warming) and toxicity related impact categories (e.g. ecotoxicity and human toxicity). The assessment addressed treatment and final placement of 1 tonne of APC residue in seven scenarios: 1) direct landfilling without treatment (baseline), 2) backfilling in salt mines, 3) neutralization of waste acid, 4) filler material in asphalt, 5) Ferrox stabilization, 6) vitrification, and 7) melting with automobile shredder residues (ASR). The management scenarios were selected as examples of the wide range of different technologies available worldwide while at the same time using realistic technology data. Results from the LCA were discussed with respect to importance of: energy consumption/substitution, material substitution, leaching, air emissions, time horizon aspects for the assessment, and transportation distances. The LCA modeling showed that thermal processes were associated with the highest loads in the non-toxicity categories (energy consumption), while differences between the remaining alternatives were small and generally considered insignificant. In the toxicity categories, all treatment/utilization options were significantly better than direct landfilling without treatment (lower leaching), although the thermal processes had somewhat higher impacts than the others options (air emissions). Transportation distances did not affect the overall ranking of the management alternatives. Copyright 2010 Elsevier B.V. All rights reserved.

Priority survey between indicators and analytic hierarchy process analysis for green chemistry technology assessment.

Science.gov (United States)

Kim, Sungjune; Hong, Seokpyo; Ahn, Kilsoo; Gong, Sungyong

2015-01-01

This study presents the indicators and proxy variables for the quantitative assessment of green chemistry technologies and evaluates the relative importance of each assessment element by consulting experts from the fields of ecology, chemistry, safety, and public health. The results collected were subjected to an analytic hierarchy process to obtain the weights of the indicators and the proxy variables. These weights may prove useful in avoiding having to resort to qualitative means in absence of weights between indicators when integrating the results of quantitative assessment by indicator. This study points to the limitations of current quantitative assessment techniques for green chemistry technologies and seeks to present the future direction for quantitative assessment of green chemistry technologies.

A DECADE OF HEALTH TECHNOLOGY ASSESSMENT IN POLAND

NARCIS (Netherlands)

Lipska, Iga; McAuslane, James Neil; Leufkens, Bert; Hövels, Anke

OBJECTIVES: The objective of this study is to illustrate and provide a better understanding of the role of health technology assessment (HTA) processes in decision making for drug reimbursement in Poland and how this approach could be considered by other countries of limited resources. METHODS: We

Wearable technology for spine movement assessment: A systematic review.

Science.gov (United States)

Papi, Enrica; Koh, Woon Senn; McGregor, Alison H

2017-11-07

Continuous monitoring of spine movement function could enhance our understanding of low back pain development. Wearable technologies have gained popularity as promising alternative to laboratory systems in allowing ambulatory movement analysis. This paper aims to review the state of art of current use of wearable technology to assess spine kinematics and kinetics. Four electronic databases and reference lists of relevant articles were searched to find studies employing wearable technologies to assess the spine in adults performing dynamic movements. Two reviewers independently identified relevant papers. Customised data extraction and quality appraisal form were developed to extrapolate key details and identify risk of biases of each study. Twenty-two articles were retrieved that met the inclusion criteria: 12 were deemed of medium quality (score 33.4-66.7%), and 10 of high quality (score >66.8%). The majority of articles (19/22) reported validation type studies. Only 6 reported data collection in real-life environments. Multiple sensors type were used: electrogoniometers (3/22), strain gauges based sensors (3/22), textile piezoresistive sensor (1/22) and accelerometers often used with gyroscopes and magnetometers (15/22). Two sensors units were mainly used and placing was commonly reported on the spine lumbar and sacral regions. The sensors were often wired to data transmitter/logger resulting in cumbersome systems. Outcomes were mostly reported relative to the lumbar segment and in the sagittal plane, including angles, range of motion, angular velocity, joint moments and forces. This review demonstrates the applicability of wearable technology to assess the spine, although this technique is still at an early stage of development. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Substitution of matrices over rings

NARCIS (Netherlands)

Hautus, M.L.J.

1995-01-01

For a given commutative ring with an identity element, we define and study the substitution of a matrix with entries in into a matrix polynomial or rational function over . A Bezout-type remainder theorem and a "partial-substitution rule" are derived and used to obtain a number of results. The

Substitution of cobalt alloying in PWR primary circuit gate valves

International Nuclear Information System (INIS)

Cachon, L.; Sudreau, F.; Brunel, L.

1995-01-01

The object of this study is qualify cobalt-free alternative alloys for valve applications. This paper focus on tribological characterization of numerous coatings is done by using the first one, of a classical type. Then tests are performed with the second one which simulates solicitations supported by gate valves in primary circuit of PWR. 35% Ni-Cr - 65% Cr 3 C 2 coating, deposited by detonation gun technology, gives us hope to find a substitute of Stelite 6. (author). 5 refs., 16 figs., 2 tabs

Demonstration of Airborne Wide Area Assessment Technologies at the Toussaint River, Ohio

National Research Council Canada - National Science Library

Foley, Jack; Wright, David

2007-01-01

...) technology, a wide area assessment technology, to assist in the characterization of the shore and shallow areas in and around the Toussaint River relative to munitions contamination from historical...

The potential impact of computer-aided assessment technology in ...

African Journals Online (AJOL)

The potential impact of computer-aided assessment technology in higher education. ... Further more 'Increased number of students in Higher Education and the ... benefits, limitations, impacts on student learning and strategies for developing ...

Experience curve analysis on South Korean nuclear technology and comparative analysis with South Korean renewable technologies

International Nuclear Information System (INIS)

Kim, Dong Wook; Chang, Hyun Joon

2012-01-01

Increasing awareness on environmental damage and climate change has induced many nations to engage in green growth. South Korea, as one of the largest consumers of energy, is no exception and has shown its determination to pursue green growth in the future. In order to do so, South Korea plans to substitute fossil fuel with alternative sources in electricity generation. However, the key constraint to green growth is the high cost faced by renewable electricity generation. Fortunately, nuclear energy can serve as an economic alternative to fossil fuel. To achieve CO 2 emission reduction and faster economic growth, it is wise to analyze prospects of alternatives using experience curve framework. The results and industry background are consistent for nuclear technology, and the results suggest that nuclear should serve as the main substitute. Consideration of policy risk inherent in renewable also strengthens the argument. Renewable technologies, on the other hand, showed overstated learning capacity that is partially inconsistent with technological background. Nevertheless, the renewable (photovoltaic and fuel cell) should help nuclear marginally in substituting fossil fuel in South Korea's Electricity Generation. - Highlights: ► Progress ratios of renewable energy show great prospect. ► The policy risk is inherent in renewable and may overestimate its prospect. ► Nuclear sources are economic and less affected by policy risk. ► Fuel cell and photovoltaic should help nuclear marginally in green growth.

Effect of lupine as cheese base substitution on technological and nutritional properties of processed cheese analogue.

Science.gov (United States)

Awad, Rezik Azab; Salama, Wafaa Mohammed; Farahat, Azza Mahmoud

2014-01-01

Healthy foods have been met with marked success in the last two decades. Lupine flours, protein concentrates, and isolates can be applied as a substance for enriching different kinds of food systems such as bakery products, lupine pasta, ice cream, milk substitutes. Imitation processed cheese is made from mixtures of dairy and/or non dairy proteins and fat/oils and is variously labeled analogue, artificial, extruded, synthetic and/or filled. Processed cheese can be formulated using different types of cheese with different degree of maturation, flavorings, emulsifying, salts, and/or several ingredients of non-dairy components. Non-dairy ingredients have been used in processed cheese for many dietary and economic reasons. In this study, lupine paste was used to substitute 25, 50, 75 and 100% of cheese in base formula of processed cheese analogue (PCA). Matured Ras cheese (3 months old) was manufactured using fresh cow milk. Soft cheese curd was manufactured using fresh buffalo skim milk. Emulsifying salts S9s and Unsalted butter were used. Lupine termis paste was prepared by soaking the seeds in tap water for week with changing the water daily, and then boiled in water for 2 hrs, cooled and peeled. The peeled seeds were minced, blended to get very fine paste and kept frozen until used. Lupine paste was used to substitute 25, 50, 75 and 100% of cheese in base formula of processed cheese analogue (PCA). The obtained PCA were analysed when fresh and during storage up to 3 months at 5±2°C for chemical composition, physical and sensory properties. The histopathological effect of lupines on alloxan diabetic albino rats and nutritional parameters were also investigated. Incorporation of lupine paste in PCA increased the ash and protein contents while meltability and penetration values of resultant products were decreased. Adding lupine in PSA formula had relatively increased the oil index and firmness of products. Feeding rats a balanced diet containing processed cheese

The Import Substitution Via the Realization of the Cluster Initiatives in the Region

Directory of Open Access Journals (Sweden)

K. I. Muhtarova

2016-01-01

Full Text Available The Russian Federation’s economic development since 2012 can be described as a difficult phase in the strengthening of international economic relations, the period of the economy’s systematic decline. The main reason is the sanctions of the USA and EU against the Russian Federation. We can assert the situation of the external credit resources lack and the impossibility of previously concluded agreements with major Western suppliers for imports of high-tech equipment implementation. It becomes necessary to implement economic incentives to support the projects of import substitution industries developing and the competitiveness of the Russian export. In this work, the formation of clusters is considered as an effective way of supporting regions of the Russian Federation in providing the aim to produce the competitive products for international food market, tourism sector, construction market and for consumer goods and high technology markets. The capital inflow reduction into the Russian Federation as a result of the ruble savings’ conversion to the dollar – is the reason of the federal and regional import substitution policy development. The next aim is the endorsement of the Russian companies’ technological cooperation with the large foreign corporations.

[Extruded rice flour as a gluten substitute in the poduction of rice bread].

Science.gov (United States)

Clerici, Maria Teresa Pedrosa Silva; El-Dash, Ahmed A

2006-09-01

Research regarding the production of gluten-free bread (GFB) is very important nutritionally, technically and economically speaking, both to celiac patients and to developing countries who import wheat. The main technological problem in the production of GFB is obtaining a gluten substitute that is both inexpensive and capable of retaining gas during bread fermentation and baking. The use of gelatinized starch as an alternative for gluten seems promising. In this project, rice bread was made using pregelatinized extruded rice flour as a gluten substitute. Pre-gelatinized rice flours (PRF) were manufactured in a single screw Brabender extruder, varying extrusion temperature (108-192 degrees C) and the moisture of the raw material (19.2 - 24.8%), and were used in a proportion of 10 g for every 100 g of raw rice flour, in the production of gluten-free bread. Results showed that rice flour extruded at a high temperature (180 degrees) and low moisture content (20%), rendered bread with the best technological characteristics, presenting crust and crumb color similar to those of conventional wheat bread, although with volume and texture not as satisfactory in the same comparison.

The Pricing Strategies and the Dominant Technology Modes

Directory of Open Access Journals (Sweden)

Kramarenko Anna О.

2017-11-01

Full Text Available The article is aimed at defining the basic approaches to pricing that correspond to the modern technological mode, as well as the prospects of substituting them with new strategies in the process of evolution of technology and socio-economic development. The technological evolution within the terms of cyclic substitution of the dominant technological ways together with periodicity of domination of the single pricing strategies have been considered. It was identified that in the process of transition to the sixth technological mode, the core of which is the high-tech and the science-driven types of economic activity, the strategies of premium pricing are at the forefront, due to their significant profitability in conditions of the fast updating of assortment of products and the particular characteristics of products and services. It has been substantiated that the dominance of premium pricing creates an inflationary effect, especially in the terms of innovative economic activities, which are potentially the basis for active implementation of technologies of the new mode.

Promoting renewable energy technologies

International Nuclear Information System (INIS)

Grenaa Jensen, S.

2004-06-01

Technologies using renewable energy sources are receiving increasing interest from both public authorities and power producing companies, mainly because of the environmental advantages they procure in comparison with conventional energy sources. These technologies can be substitution for conventional energy sources and limit damage to the environment. Furthermore, several of the renewable energy technologies satisfy an increasing political goal of self-sufficiency within energy production. The subject of this thesis is promotion of renewable technologies. The primary goal is to increase understanding on how technological development takes place, and establish a theoretical framework that can assist in the construction of policy strategies including instruments for promotion of renewable energy technologies. Technological development is analysed by through quantitative and qualitative methods. (BA)

Zinc and Carbonate Co-Substituted Nano-Hydroxyapatite

Science.gov (United States)

Girija, E. K.; Kumar, G. Suresh; Thamizhavel, A.

2011-07-01

Synthesis of Zn or CO32- substituted nano-hydroxyapatite (HA) and its physico-chemical properties have been well documented. However, the effects of the simultaneous substitution of Zn and CO32- in nano-HA have not been reported. In the present study, Zn and CO32- substitutions in nano HA independently and concurrently have been done by wet precipitation method and characterized by XRD and FT-IR for its phase purity and chemical homogeneity. Further modulations of the bioactivity and thermal stability of HA due to the substitutions have been studied.

A Sustainability Assessment Methodology for Prioritizing the Technologies of Groundwater Contamination Remediation

DEFF Research Database (Denmark)

An, Da; Xi, Beidou; Wang, Yue

2016-01-01

More and more groundwater has 23 been polluted recently, and technologies for groundwater contamination remediation are of vital importance; however, it is usually difficult for the users to select the most suitable technology among multiple alternatives. In order to address this, this study aims...... at developing a sustainability assessment framework for prioritizing the technologies for groundwater contamination remediation by combining the concept of sustainability and multi-criteria decision making (MCDM) method. A criterion system which consists of six criteria in three aspects has been proposed...... for sustainability assessment of technologies for groundwater contamination remediation, and a novel MCDM method by combining the logarithmic fuzzy preference programming based fuzzy analytic hierarchy process and the improved ELECTRE method has been developed for prioritizing the alternatives. In order...

Technology Readiness Level Assessment Process as Applied to NASA Earth Science Missions

Science.gov (United States)

Leete, Stephen J.; Romero, Raul A.; Dempsey, James A.; Carey, John P.; Cline, Helmut P.; Lively, Carey F.

2015-01-01

Technology assessments of fourteen science instruments were conducted within NASA using the NASA Technology Readiness Level (TRL) Metric. The instruments were part of three NASA Earth Science Decadal Survey missions in pre-formulation. The Earth Systematic Missions Program (ESMP) Systems Engineering Working Group (SEWG), composed of members of three NASA Centers, provided a newly modified electronic workbook to be completed, with instructions. Each instrument development team performed an internal assessment of its technology status, prepared an overview of its instrument, and completed the workbook with the results of its assessment. A team from the ESMP SEWG met with each instrument team and provided feedback. The instrument teams then reported through the Program Scientist for their respective missions to NASA's Earth Science Division (ESD) on technology readiness, taking the SEWG input into account. The instruments were found to have a range of TRL from 4 to 7. Lessons Learned are presented; however, due to the competition-sensitive nature of the assessments, the results for specific missions are not presented. The assessments were generally successful, and produced useful results for the agency. The SEWG team identified a number of potential improvements to the process. Particular focus was on ensuring traceability to guiding NASA documents, including the NASA Systems Engineering Handbook. The TRL Workbook has been substantially modified, and the revised workbook is described.

Environmental assessment of solid waste systems and technologies: EASEWASTE

DEFF Research Database (Denmark)

Kirkeby, Janus Torsten; Birgisdottir, Harpa; Hansen, Trine Lund

2006-01-01

A new model has been developed for evaluating the overall resource consumption and environmental impacts of municipal solid waste management systems by the use of life cycle assessment. The model is named EASEWASTE (Environmental Assessment of Solid Waste Systems and Technologies) and is able...... may not always be the most environmentally friendly. The EASEWASTE model can identify the most environmentally sustainable solution, which may differ among waste materials and regions and can add valuable information about environmental achievements from each process in a solid waste management system....... to compare different waste management strategies, waste treatment methods and waste process technologies. The potential environmental impacts can be traced back to the most important processes and waste fractions that contribute to the relevant impacts. A model like EASEWASTE can be used by waste planners...

Renewable Substitutability Index: Maximizing Renewable Resource Use in Buildings

Directory of Open Access Journals (Sweden)

Ravi S. Srinivasan

2015-05-01

Full Text Available In order to achieve a material and energy balance in buildings that is sustainable in the long run, there is an urgent need to assess the renewable and non-renewable resources used in the manufacturing process and to progressively replace non-renewable resources with renewables. Such progressive disinvestment in the non-renewable resources that may be substituted with renewable resources is referred to as “Renewable Substitutability” and if implemented, this process will lead to a paradigm shift in the way building materials are manufactured. This paper discusses the development of a Renewable Substitutability Index (RSI that is designed to maximize the use of renewable resources in a building and quantifies the substitution process using solar emergy (i.e., the solar equivalent joules required for any item. The RSI of a building or a building component, i.e., floor or wall systems, etc., is the ratio of the renewable resources used during construction, including replacement and maintenance, to the building’s maximum renewable emergy potential. RSI values range between 0 and 1.0. A higher RSI achieves a low-energy building strategy promoting a higher order of sustainability by optimizing the use of renewables over a building’s lifetime from formation-extraction-manufacturing to maintenance, operation, demolition, and recycle.

Assessing the impacts of changes in treatment technology on energy and greenhouse gas balances for organic waste and wastewater treatment using historical data.

Science.gov (United States)

Poulsen, Tjalfe G; Hansen, Jens Aage

2009-11-01

Historical data on organic waste and wastewater treatment during the period of 1970-2020 were used to assess the impact of treatment on energy and greenhouse gas (GHG) balances. The assessment included the waste fractions: Sewage sludge, food waste, yard waste and other organic waste (paper, plastic, etc.). Data were collected from Aalborg, a municipality located in Northern Denmark. During the period from 1970-2005, Aalborg Municipality has changed its waste treatment strategy from landfilling of all wastes toward composting of yard waste and incineration with combined heat and power production from the remaining organic municipal waste. Wastewater treatment has changed from direct discharge of untreated wastewater to full organic matter and nutrient (N, P) removal combined with anaerobic digestion of the sludge for biogas production with power and heat generation. These changes in treatment technology have resulted in the waste and wastewater treatment systems in Aalborg progressing from being net consumers of energy and net emitters of GHG, to becoming net producers of energy and net savers of GHG emissions (due to substitution of fossil fuels elsewhere). If it is assumed that the organic waste quantity and composition is the same in 1970 and 2005, the technology change over this time period has resulted in a progression from a net annual GHG emission of 200 kg CO( 2)-eq. capita(-1) in 1970 to a net saving of 170 kg CO(2)-eq. capita(-1) in 2005 for management of urban organic wastes.

Percutaneous fetoscopic closure of large open spina bifida using a bilaminar skin substitute.

Science.gov (United States)

Lapa Pedreira, Denise A; Acacio, Gregório L; Gonçalves, Rodrigo T; Sá, Renato Augusto M; Brandt, Reynaldo A; Chmait, Ramen; Kontopoulos, Eftichia; Quintero, Ruben A

2018-01-04

We have previously described our percutaneous fetoscopic technique for the treatment of open spina bifida (OSB). However, approximately 20-30% of OSB defects are too large to allow primary skin closure. We hereby describe a modification of our standard technique using a bilaminar skin substitute to allow closure of such large spinal defects. The aim of this study was to report our clinical experience with the use of a bilaminar skin substitute and a percutaneous fetoscopic technique for the prenatal closure of large spina bifida defects. Surgeries were performed between 24.0 and 28.9 gestational weeks under general anesthesia, using an entirely percutaneous fetoscopic approach with partial CO2 insufflation of the uterine cavity, as previously described. If there was enough skin to be sutured in the midline, only a biocellulose patch was placed over the placode. In cases where skin approximation was not possible, a bilaminar skin substitute (two layers: one silicone and one dermal matrix) was placed over the biocellulose. The surgical site was assessed at birth, and long-term follow-up was performed. Forty-seven consecutive fetuses underwent percutaneous fetoscopic OSB repair. Premature preterm rupture of membranes (PPROM) occurred in 38 (84%), and the mean gestational age at delivery was 32,8 + 2.5 weeks. A bilaminar skin substitute was required in 13 (29%), of which 5 was associated with myeloschisis. In all cases the skin substitute was found at the surgical site, at birth. In 3 (15%) of these cases, postnatal additional repair was needed. In the other 10 cases, the silicone layer detached spontaneously from the dermal matrix (average 25 days after birth), and the lesion healed by secondary-intention. Operating time was significantly longer in cases requiring the bilaminar skin substitute (additional 42 minutes). The subgroup with bilaminar skin substitute had similar PPROM rate and delivery gestational age compared to the one patch group. Complete reversal of

A model for assessing information technology effectiveness in the business environment

Directory of Open Access Journals (Sweden)

Sandra Cristina Riascos Erazo

2008-05-01

Full Text Available The impact of technology on administrative processes has improved business strategies (especially regarding the e-ffect of information technology - IT, often leading to organisational success. Its effectiveness in this environment was thus modelled due to such importance; this paper describes studying a series of models aimed at assessing IT, its ad-vantages and disadvantages. A model is proposed involving different aspects for an integral assessment of IT effecti-veness and considering administrative activities’ particular characteristics. This analytical study provides guidelines for identifying IT effectiveness in a business environment and current key strategies in technological innovation. This stu-dy was based on ISO 9126, ISO 9001, ISO 15939 and ISO 25000 standards as well as COBIT and CMM stan-dards.

Melter Technologies Assessment

Energy Technology Data Exchange (ETDEWEB)

Perez, J.M. Jr. [Pacific Northwest National Lab., Richland, WA (United States); Schumacher, R.F. [Savannah River Technology Center, Aiken, SC (United States); Forsberg, C.W. [Oak Ridge National Lab., TN (United States)

1996-05-01

The problem of controlling and disposing of surplus fissile material, in particular plutonium, is being addressed by the US Department of Energy (DOE). Immobilization of plutonium by vitrification has been identified as a promising solution. The Melter Evaluation Activity of DOE`s Plutonium Immobilization Task is responsible for evaluating and selecting the preferred melter technologies for vitrification for each of three immobilization options: Greenfield Facility, Adjunct Melter Facility, and Can-In-Canister. A significant number of melter technologies are available for evaluation as a result of vitrification research and development throughout the international communities for over 20 years. This paper describes an evaluation process which will establish the specific requirements of performance against which candidate melter technologies can be carefully evaluated. Melter technologies that have been identified are also described.

Determinants of generic drug substitution in Switzerland

Directory of Open Access Journals (Sweden)

Lufkin Thomas M

2011-01-01

Full Text Available Abstract Background Since generic drugs have the same therapeutic effect as the original formulation but at generally lower costs, their use should be more heavily promoted. However, a considerable number of barriers to their wider use have been observed in many countries. The present study examines the influence of patients, physicians and certain characteristics of the generics' market on generic substitution in Switzerland. Methods We used reimbursement claims' data submitted to a large health insurer by insured individuals living in one of Switzerland's three linguistic regions during 2003. All dispensed drugs studied here were substitutable. The outcome (use of a generic or not was modelled by logistic regression, adjusted for patients' characteristics (gender, age, treatment complexity, substitution groups and with several variables describing reimbursement incentives (deductible, co-payments and the generics' market (prices, packaging, co-branded original, number of available generics, etc.. Results The overall generics' substitution rate for 173,212 dispensed prescriptions was 31%, though this varied considerably across cantons. Poor health status (older patients, complex treatments was associated with lower generic use. Higher rates were associated with higher out-of-pocket costs, greater price differences between the original and the generic, and with the number of generics on the market, while reformulation and repackaging were associated with lower rates. The substitution rate was 13% lower among hospital physicians. The adoption of the prescribing practices of the canton with the highest substitution rate would increase substitution in other cantons to as much as 26%. Conclusions Patient health status explained a part of the reluctance to substitute an original formulation by a generic. Economic incentives were efficient, but with a moderate global effect. The huge interregional differences indicated that prescribing behaviours and

Environmental Assessment of Micro/Nano Production in a Life Cycle Perspective

DEFF Research Database (Denmark)

Olsen, Stig Irving; Jørgensen, Michael Søgaard

2006-01-01

demands, which balances or overcompensates the savings. In the Micro/Nano Production area a range of new possibilities arise both within applications, production technology and materials. The Department of Manufacturing Engineering and Management at The Technical University of Denmark has staked...... to a number of knowledge gaps. It may not be known exactly what is the function (or functional unit) or what the technology may substitute and production may still be at an experimental level, raising questions about technology or materials choice. For prospective LCA studies methodologies like “consequential...... understanding of the environment, precaution as a principle and finally, prevention as preferred strategy. When assessing emerging technologies three levels should be considered. First order effects are connected directly to production, use and disposal. Second order are effects from interaction with other...

A State-of-the-Art Report on Technologies of a Safety Assessment and a Radioactivity Exposure Assessment for the Decommissioning Process of Nuclear Facilities

International Nuclear Information System (INIS)

Jeong, Kwan Seong; Kang, Young Ae; Lee, Dong Gyu; Lee, Kune Woo; Jung, Chong Hun

2007-09-01

This report is to provide the reference contents of research and development for technologies of radioactivity exposure and safety assessment for development of the decommissioning technology for nuclear facilities. This report consists of as follows: - Analyzing and discussing on state-of-the-art technologies of a radioactivity exposure assessment of a decommissioning for nuclear facilities - Analyzing and discussing on state-of-the-art technologies of a safety assessment of a decommissioning for nuclear facilities

A State-of-the-Art Report on Technologies of a Safety Assessment and a Radioactivity Exposure Assessment for the Decommissioning Process of Nuclear Facilities

Energy Technology Data Exchange (ETDEWEB)

Jeong, Kwan Seong; Kang, Young Ae; Lee, Dong Gyu; Lee, Kune Woo; Jung, Chong Hun

2007-09-15

This report is to provide the reference contents of research and development for technologies of radioactivity exposure and safety assessment for development of the decommissioning technology for nuclear facilities. This report consists of as follows: - Analyzing and discussing on state-of-the-art technologies of a radioactivity exposure assessment of a decommissioning for nuclear facilities - Analyzing and discussing on state-of-the-art technologies of a safety assessment of a decommissioning for nuclear facilities.

Food intake regulation in children. Fat and sugar substitutes and intake.

Science.gov (United States)

Birch, L L; Fisher, J O

1997-05-23

A series of experiments exploring children's responsiveness to manipulations of energy density and macronutrient content of foods have been reviewed to assess the nutritional impact of macronutrient substitutes on children's intake. In these experiments, the focus is on the extent to which the energy content of foods was a salient factor influencing children's food intake, and macronutrient substitutes were used as tools to investigate this issue. Therefore, although several different macronutrient substitutes have been used in this research, we do not have a parametric set of experiments systematically assessing the impact of a variety of macronutrient substitutes. Given this, what can we conclude from the existing data? When the energy density and macronutrient content of foods is altered through the use of macronutrient substitutes that reduce the energy content of foods, children tend to adjust for the missing energy, although this adjustment may be partial and incomplete. This suggests the possibility that when macronutrient substitutes are used to reduce the energy content of foods, children's energy intake may be reduced. This adjustment, however, will most likely be less than a "calorie for calorie" reduction. In addition, even among young children, there are individual differences in the extent to which children adjust their intake in response to macronutrient and energy manipulations. The data are more extensive and particularly clear for cases in which CHO manipulations are used to alter energy density, but there is evidence for adjustments in energy intake in response to alterations of the fat content of the diet. The compensation for energy is not macronutrient specific; that is, when the fat content of food is reduced to reduce energy density of foods, children do not selectively consume fat in subsequent meals. This means that manipulations of macronutrient content of foods that reduce foods' energy content may not result in alterations of energy

A Conceptual Methodology for Assessing Acquisition Requirements Robustness against Technology Uncertainties

Science.gov (United States)

Chou, Shuo-Ju

2011-12-01

In recent years the United States has shifted from a threat-based acquisition policy that developed systems for countering specific threats to a capabilities-based strategy that emphasizes the acquisition of systems that provide critical national defense capabilities. This shift in policy, in theory, allows for the creation of an "optimal force" that is robust against current and future threats regardless of the tactics and scenario involved. In broad terms, robustness can be defined as the insensitivity of an outcome to "noise" or non-controlled variables. Within this context, the outcome is the successful achievement of defense strategies and the noise variables are tactics and scenarios that will be associated with current and future enemies. Unfortunately, a lack of system capability, budget, and schedule robustness against technology performance and development uncertainties has led to major setbacks in recent acquisition programs. This lack of robustness stems from the fact that immature technologies have uncertainties in their expected performance, development cost, and schedule that cause to variations in system effectiveness and program development budget and schedule requirements. Unfortunately, the Technology Readiness Assessment process currently used by acquisition program managers and decision-makers to measure technology uncertainty during critical program decision junctions does not adequately capture the impact of technology performance and development uncertainty on program capability and development metrics. The Technology Readiness Level metric employed by the TRA to describe program technology elements uncertainties can only provide a qualitative and non-descript estimation of the technology uncertainties. In order to assess program robustness, specifically requirements robustness, against technology performance and development uncertainties, a new process is needed. This process should provide acquisition program managers and decision

Substitution within the Danish printing industry

DEFF Research Database (Denmark)

Larsen, Henrik Fred; Bøg, Carsten

2009-01-01

are running a substitution project. A major part of the work has been mapping the presence of chemicals which are potential candidates for substitution (e.g. PBT, CMR, vPvB, EDS) within the Danish printing industry and this work was recently finished. The mapping comprises a combination of a literature study......The implementation of the EU REACH regulation will most probably promote substitution within sectors handling a lot of different chemicals like the printing industry. With the aim of being at the cutting edge of this development the Danish EPA together with the Danish printing industry and IPU...... total 15 substances) were found in the Danish printing industry. This paper presents the results of the mapping of chemical candidates and the first results on preparing for actual substitutions....

National Wind Technology Center sitewide, Golden, CO: Environmental assessment

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-11-01

The National Renewable Energy Laboratory (NREL), the nation`s primary solar and renewable energy research laboratory, proposes to expand its wind technology research and development program activities at its National Wind Technology Center (NWTC) near Golden, Colorado. NWTC is an existing wind energy research facility operated by NREL for the US Department of Energy (DOE). Proposed activities include the construction and reuse of buildings and facilities, installation of up to 20 wind turbine test sites, improvements in infrastructure, and subsequent research activities, technology testing, and site operations. In addition to wind turbine test activities, NWTC may be used to support other NREL program activities and small-scale demonstration projects. This document assesses potential consequences to resources within the physical, biological, and human environment, including potential impacts to: air quality, geology and soils, water resources, biological resources, cultural and historic resources, socioeconomic resources, land use, visual resources, noise environment, hazardous materials and waste management, and health and safety conditions. Comment letters were received from several agencies in response to the scoping and predecisional draft reviews. The comments have been incorporated as appropriate into the document with full text of the letters contained in the Appendices. Additionally, information from the Rocky Flats Environmental Technology Site on going sitewide assessment of potential environmental impacts has been reviewed and discussed by representatives of both parties and incorporated into the document as appropriate.

National Wind Technology Center sitewide, Golden, CO: Environmental assessment

International Nuclear Information System (INIS)

1996-11-01

The National Renewable Energy Laboratory (NREL), the nation's primary solar and renewable energy research laboratory, proposes to expand its wind technology research and development program activities at its National Wind Technology Center (NWTC) near Golden, Colorado. NWTC is an existing wind energy research facility operated by NREL for the US Department of Energy (DOE). Proposed activities include the construction and reuse of buildings and facilities, installation of up to 20 wind turbine test sites, improvements in infrastructure, and subsequent research activities, technology testing, and site operations. In addition to wind turbine test activities, NWTC may be used to support other NREL program activities and small-scale demonstration projects. This document assesses potential consequences to resources within the physical, biological, and human environment, including potential impacts to: air quality, geology and soils, water resources, biological resources, cultural and historic resources, socioeconomic resources, land use, visual resources, noise environment, hazardous materials and waste management, and health and safety conditions. Comment letters were received from several agencies in response to the scoping and predecisional draft reviews. The comments have been incorporated as appropriate into the document with full text of the letters contained in the Appendices. Additionally, information from the Rocky Flats Environmental Technology Site on going sitewide assessment of potential environmental impacts has been reviewed and discussed by representatives of both parties and incorporated into the document as appropriate

Can we reliably benchmark health technology assessment organizations?

Science.gov (United States)

Drummond, Michael; Neumann, Peter; Jönsson, Bengt; Luce, Bryan; Schwartz, J Sanford; Siebert, Uwe; Sullivan, Sean D

2012-04-01

In recent years, there has been growth in the use of health technology assessment (HTA) for making decisions about the reimbursement, coverage, or guidance on the use of health technologies. Given this greater emphasis on the use of HTA, it is important to develop standards of good practice and to benchmark the various HTA organizations against these standards. This study discusses the conceptual and methodological challenges associated with benchmarking HTA organizations and proposes a series of audit questions based on a previously published set of principles of good practice. It is concluded that a benchmarking exercise would be feasible and useful, although the question of who should do the benchmarking requires further discussion. Key issues for further research are the alternative methods for weighting the various principles and for generating an overall score, or summary statement of adherence to the principles. Any weighting system, if developed, would need to be explored in different jurisdictions to assess the extent to which the relative importance of the principles is perceived to vary. Finally, the development and precise wording of the audit questions requires further study, with a view to making the questions as unambiguous as possible, and the reproducibility of the assessments as high as possible.

PRELIMINARY ASSESSMENT OF THE LOW-TEMPERATURE WASTE FORM TECHNOLOGY COUPLED WITH TECHNETIUM REMOVAL

Energy Technology Data Exchange (ETDEWEB)

Fox, K.

2014-05-13

The U.S. Department of Energy Office of Environmental Management (EM) is engaging the national laboratories to provide the scientific and technological rigor to support EM program and project planning, technology development and deployment, project execution, and assessment of program outcomes. As an early demonstration of this new responsibility, Pacific Northwest National Laboratory (PNNL) and Savannah River National Laboratory (SRNL) have been chartered to implement a science and technology program addressing low-temperature waste forms for immobilization of DOE aqueous waste streams, including technetium removal as an implementing technology. As a first step, the laboratories examined the technical risks and uncertainties associated with the Cast Stone waste immobilization projects at Hanford. Science and technology needs were identified for work associated with 1) conducting performance assessments and risk assessments of waste form and disposal system performance, and 2) technetium chemistry in tank wastes and separations of technetium from waste processing streams. Technical approaches to address the science and technology needs were identified and an initial sequencing priority was suggested. The following table summarizes the most significant science and technology needs and associated approaches to address those needs. These approaches and priorities will be further refined and developed as strong integrated teams of researchers from national laboratories, contractors, industry, and academia are brought together to provide the best science and technology solutions. Implementation of a science and technology program that addresses these needs by pursuing the identified approaches will have immediate benefits to DOE in reducing risks and uncertainties associated with near-term decisions regarding supplemental immobilization at Hanford. Longer term, the work has the potential for cost savings and for providing a strong technical foundation for future

Associations between generic substitution and patients' attitudes, beliefs and experience

DEFF Research Database (Denmark)

Østergaard Rathe, Jette; Larsen, Pia Veldt; Andersen, Morten

2013-01-01

Abstract Background Generic substitution has been implemented in many countries, but knowledge about patients’ attitudes, beliefs and experiences is still sparse. Aim To assess associations between generic switching and patients’ attitudes, beliefs and experiences with previous generic switching...... on generic medicine and confidence in the healthcare system. Only prescriptions issued by the general practitioners were included. For each patient we focused on one purchase of a generically substitutable drug (index drug). Patients were identified by means of a dispensing database. Results Earlier generic...... switches within the index ATC code were statistically significantly associated with experience of a generic switch (adjusted OR 5.93 95% CI 4.70; 7.49). Having had more than 5 earlier switches within other ATC codes and having negative views on generic medicines reduced the odds of experiencing a generic...

Using technology to assess and intervene with illicit drug-using persons at risk for HIV.

Science.gov (United States)

Horvath, Keith J; Lammert, Sara; LeGrand, Sara; Muessig, Kathryn E; Bauermeister, José A

2017-09-01

This review describes recent literature on novel ways technology is used for assessment of illicit drug use and HIV risk behaviours, suggestions for optimizing intervention acceptability, and recently completed and ongoing technology-based interventions for drug-using persons at risk for HIV and others with high rates of drug use and HIV risk behaviour. Among studies (n = 5) comparing technology-based to traditional assessment methods, those using Ecological Momentary Assessment (EMA) had high rates of reported drug use and high concordance with traditional assessment methods. The two recent studies assessing the acceptability of mHealth approaches overall demonstrate high interest in these approaches. Current or in-progress technology-based interventions (n = 8) are delivered using mobile apps (n = 5), text messaging (n = 2) and computers (n = 1). Most intervention studies are in progress or do not report intervention outcomes; the results from one efficacy trial showed significantly higher HIV testing rates among persons in need of drug treatment. Studies are needed to continually assess technology adoption and intervention preferences among drug-using populations to ensure that interventions are appropriately matched to users. Large-scale technology-based intervention trials to assess the efficacy of these approaches, as well as the impact of individual intervention components, on drug use and other high-risk behaviours are recommended.

Noval 1-substituted-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazole derivatives: Synthesis and pharmacological activity

Directory of Open Access Journals (Sweden)

Sabir Hussain

2015-05-01

Full Text Available Several-1-carbothioamide-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 2a–d, 1-(pyridine-4-ylcarbonyl-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 3a–d, 1-(5-chloro-6-fluoro-1,3-benzothiazole-2-ylthiocarbamoyl-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 4a–d and 1-[(1,2,4-triazole-4-yl carbothioamide]-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 5a–d were synthesized. The structures of the newly synthesized compounds were supported by IR, 1H NMR and mass spectral data. These compounds were investigated for their, anti-inflammatory, analgesic, ulcerogenic, lipid peroxidation, antibacterial and antifungal activities. Some of the synthesized compounds showed potent anti-inflammatory activity along with minimal ulcerogenic effect and lipid peroxidation, compared to ibuprofen and flurbiprofen. Some of the tested compounds also showed moderate antimicrobial activity against tested bacterial and fungal strains.

Public policies for energy substitution in bus: the case of city of Sao Paulo; Politicas publicas para a substituicao energetica em onibus: o caso da cidade de Sao Paulo

Energy Technology Data Exchange (ETDEWEB)

Araujo, Gregorio da Cruz; Zisman, Sandra Francis [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

2012-07-01

Brazil has been on a leading position on fossil fuel substitution in light vehicles. In 2008 and 2009, ethanol contributed with more than 50% of the light vehicle fuel's consumption. A new energetic substitution program was launched in Sao Paulo, and it can be the turning point for the fossil fuel's substitution in the segment of collective transport. This program allows the development of new fuel and engine technologies, and creates opportunities for their deployment on the collective transport market. The economic consequence is a restructuring process that affects the already established markets. There are still big uncertainties about the program's execution, and also about what will be the winning solutions of this, already started, technological race. (author)

Appropriateness, acceptance and sensory preferences based on visual information: A web-based survey on meat substitutes in a meal context

NARCIS (Netherlands)

Elzerman, J.E.; Hoek, A.C.; Boekel, van T.; Luning, P.A.

2015-01-01

The aim of this study was to investigate the appropriateness, attractiveness, use-intention and (un)desirable sensory properties of meat substitutes in different dishes based only on visual information. A web-based survey was developed to let consumers assess the use of meat substitutes in different

Assessing systemwide occupational health and safety risks of energy technologies

International Nuclear Information System (INIS)

Rowe, M.D.

1982-01-01

Input-output modelling is now being used to assess systemwide occupational and public health and safety risks of energy technologies. Some of the advantages and disadvantages of this method are presented and some of its important limitations are discussed. Its primary advantage is that it provides a standard method with which to compare technologies on a consistent basis without extensive economic analysis. Among the disadvantages are limited range of applicability, limited spectrum of health impacts, and inability to identify unusual health impacts unique to a new technology. (author)

Financial mechanisms and social safety-oriented model of development of the Russian economy (based on import substitution and innovation

Directory of Open Access Journals (Sweden)

T. I. Ovchinnikova

2016-01-01

Full Text Available In article features of import substitution in the socially oriented model determined as economy with the high level of the state income redistribution of subjects of managing and developed on this basis of system of social protection are considered. Import substitution is considered from the traditional point of view – creation of new productions and technologies which are implemented at the expense of own and borrowed funds of investors. The financial mechanisms for implementation of innovations promoting import substitution are offered: industry plans and road maps as availability of reference points for creation of rational amounts of the budget payments and financial resources of the entities necessary for upgrade of productions, and also the directions of financial resources for implementation of specific most important national priorities and innovative investment projects. The volume of investment into the fixed capital correlated to its cost considerably grew from 3.5% in 2003 to 11.6% in 2009, but value of this indicator isn't enough as degree of depreciation of fixed assets in economy of the region constituted 44.9% in 2009. Direct foreign investments prevail: in Krasnoyarsk Krai their share constituted in 2009 – 45.4%, Krasnodar Region – 40.5%, the Nizhny Novgorod Region – 84.5%. In the Voronezh region such entities as KBHA, Federal State Unitary Enterprise State Research and Production Space Center branch of M. V. Khrunichev the Voronezh Mechanical Plant, JSC Sozvezdiye Concern having the high technologies making safety of the country and especially needing investments function. In plans of urgent strategy of social and economic development of the Voronezh region it is supposed to increase specific weight of innovative products of such entities and to increase the level of innovative activity till 2020. The socially oriented model considering import substitution domestic technologies and products needs strengthening of the

Antimony substitution in SmFeAsO

Energy Technology Data Exchange (ETDEWEB)

Schmidt, Daniel; Braun, Hans F. [Universitaet Bayreuth (Germany)

2015-07-01

In the iron based compounds structural and magnetic phase transitions can be suppressed by applying external hydrostatic pressure and superconductivity emerges. Beside hydrostatic pressure, it is possible to apply chemical pressure by the substitution of atoms in the compounds with smaller ones. Such a substitution was successful for example in LaFeAs{sub 1-x}P{sub x}O, where the parent compound shows a structural and a spin-density-wave transition and the P doped samples become superconducting. We are interested in the opposite way and substitute the As by the bigger Sb. In literature, the substitution in the La-1111 compounds was possible up to a substitution level of 40 %. With Sm, instead of La, we used a smaller rare-earth metal. We present the results obtained on polycrystalline samples characterized by Xray powder diffraction and resistivity measurements.