WorldWideScience

Sample records for technologies regulatory issues

  1. Regulatory framework in assisted reproductive technologies, relevance and main issues.

    Directory of Open Access Journals (Sweden)

    Françoise Merlet

    2010-01-01

    Full Text Available Assisted reproductive technologies (ART have changed life for the past 25 years and many ethical and social issues have emerged following this new method of conception. In order to protect individuals against scientific and ethical abuses without inhibiting scientific progress, a specific legal framework is necessary. The first French law on Bioethics was voted after an extensive debate in 1994 then reviewed in 2004. This review previously scheduled every five years is currently being discussed. Legal provisions applying to ART are part of a large framework including the protection of the patients' rights and biomedical research. The key principles consist of respect for human life and ban on commercial practices of human body parts, eugenic practices and any kind of cloning. These key principles apply to ART. Donation is anonymous and free. Created in 2004, the Agence de la biomĂŠdecine is a government agency and one of the main tools of the French regulations. The missions focus on improving the quality and the safety of the management of ART. Evaluation of activities is available to all from the annual report. The agency represents the French competent authority for medical and scientific aspects of ART. Substantial differences in European legislations exist from the open-up "laissez faire" to the most restrictive one. As a consequence a large reproductive tourism has developed particularly for egg donation or surrogacy. The medical and ethical conditions of management of patients and donors represent the main critical points. In order to avoid ethical abuses, homogenization regarding the key principles is necessary in Europe. It is an opportunity to reassert that human body parts should not be a source of financial gain.

  2. Regulatory framework in assisted reproductive technologies, relevance and main issues.

    Science.gov (United States)

    Merlet, Françoise

    2009-01-01

    Assisted reproductive technologies (ART) have changed life for the past 25 years and many ethical and social issues have emerged following this new method of conception. In order to protect individuals against scientific and ethical abuses without inhibiting scientific progress, a specific legal framework is necessary. The first French law on Bioethics was voted after an extensive debate in 1994 then reviewed in 2004. This review previously scheduled every five years is currently being discussed. Legal provisions applying to ART are part of a large framework including the protection of the patients' rights and biomedical research. The key principles consist of respect for human life and ban on commercial practices of human body parts, eugenic practices and any kind of cloning. These key principles apply to ART. Donation is anonymous and free. Created in 2004, the Agence de la biomédecine is a government agency and one of the main tools of the French regulations. The missions focus on improving the quality and the safety of the management of ART. Evaluation of activities is available to all from the annual report. The agency represents the French competent authority for medical and scientific aspects of ART. Substantial differences in European legislations exist from the open-up "laissez faire" to the most restrictive one. As a consequence a large reproductive tourism has developed particularly for egg donation or surrogacy. The medical and ethical conditions of management of patients and donors represent the main critical points. In order to avoid ethical abuses, homogenization regarding the key principles is necessary in Europe. It is an opportunity to reassert that human body parts should not be a source of financial gain.

  3. Structural Analysis of the Global Multimedia Scenario: Technological, Market, Environmental, and Regulatory Issues.

    Science.gov (United States)

    Nicolo, Enrico; Sapio, Bartolomeo

    1996-01-01

    Presents a strategic evaluation of the global multimedia scenario, considering both stand-alone workstations and distributed multimedia in the worldwide interactive network, including educational databases on the Internet. Discusses 50 technological, market, environmental, and regulatory factors and estimates their impacts on each other using WISE…

  4. Clinical research: regulatory issues.

    Science.gov (United States)

    Wermeling, D P

    1999-02-01

    The regulatory issues faced by institutions performing clinical research are described. Many institutions do not have on staff an expert who understands the regulatory issues involved in managing investigational new drug research and who knows the institution's obligations under the federal rules. Because pharmacists understand the FDA regulations that apply to the management of drugs in clinical research, institutions are asking pharmacists to expand their role and manage clinical research offices. Many authorities govern various aspects of investigational drug research. FDA has published regulations for good clinical practice (GCP), and the International Conference on Harmonisation is developing an international standard for the proper management of clinical trials. The guidelines published by the Joint Commission on Accreditation of Healthcare Organizations aim to protect patients who are in the institution to receive health care and also participate in clinical trials. The Social Security Administration Acts specifically state that only items and services that are reasonable and necessary for the diagnosis and treatment of injury or disease can be billed to the government; research-related billings are excluded from coverage. Proper management of drug research is crucial to the success of a research program that is integrated with patient care.

  5. IT Legislative and Regulatory Issues Agenda. Higher Education Information Technology Alliance

    Science.gov (United States)

    National Association of State Universities and Land-Grant Colleges, 2004

    2004-01-01

    This document represents the higher education and library community's guiding public policy agenda on information technology (IT) for the current year. The Higher Education Information Technology (HEIT) Alliance is a coalition of 11 national higher education and library associations, whose members represent a broad array of stakeholders on college…

  6. Regulatory and Permitting Issues

    Energy Technology Data Exchange (ETDEWEB)

    Larry Myer

    2005-12-01

    As part of the West Coast Regional Carbon Sequestration Partnership (WESTCARB), Terralog Technologies USA, Inc., reviewed current state and federal regulations related to carbon dioxide capture and storage within geologic formations and enhanced carbon uptake in terrestrial ecosystems. We have evaluated and summarized the current and possible future permitting requirements for the six states that comprise the West Coast Regional Partnership. Four options exist for CO{sub 2} injection into appropriate geologic formations, including storage in: (1) oil and gas reservoirs, (2) saline formations, (3) unmineable coal beds, and (4) salt caverns. Terrestrial CO{sub 2} sequestration involves improved carbon conservation management (e.g. reduction of deforestation), carbon substitution (e.g., substitution for fossil fuel-based products, energy conservation through urban forestry, biomass for energy generation), and improved carbon storage management (e.g., expanding the storage of carbon in forest ecosystems). The primary terrestrial options for the West Coast Region include: (1) reforestation of under-producing lands (including streamside forest restoration), (2) improved forest management, (3) forest protection and conservation, and (4) fuel treatments for the reduction of risk of uncharacteristically severe fires (potentially with associated biomass energy generation). The permits and/or contracts required for any land-use changes/disturbances and biomass energy generation that may occur as part of WESTCARB's activities have been summarized for each state.

  7. Regulatory Issues Surrounding Merchant Interconnection

    Energy Technology Data Exchange (ETDEWEB)

    Kuijlaars, Kees-Jan; Zwart, Gijsbert [Office for Energy Regulation (DTe), The Hague (Netherlands)

    2003-11-01

    We discussed various issues concerning the regulatory perspective on private investment in interconnectors. One might claim that leaving investment in transmission infrastructure to competing market parties is more efficient than relying on regulated investment only (especially in the case of long (DC) lines connecting previously unconnected parts of the grids, so that externalities from e.g. loop flows do not play a significant role). We considered that some aspects of interconnection might reduce these market benefits. In particular, the large fixed costs of interconnection construction may lead to significant under investment (due to both first mover monopoly power and the fact that part of generation cost efficiencies realised by interconnection are not captured by the investor itself, and remain external to the investment decision). Second, merchant ownership restricts future opportunities for adaptation of regulation, as would be required e.g. for introduction of potentially more sophisticated methods of congestion management or market splitting. Some of the disadvantages of merchant investment may be mitigated however by a suitable regulatory framework, and we discussed some views in this direction. The issues we discussed are not intended to give a complete framework, and detailed regulation will certainly involve many more specific requirements. Areas we did not touch upon include e.g. the treatment of deep connection costs, rules for operation and maintenance of the line, and impact on availability of capacity on other interconnections.

  8. Legal and regulatory issues affecting compressed air energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Hendrickson, P.L.

    1981-07-01

    Several regulatory and legal issues that can potentially affect implementation of a compressed air energy storage (CAES) system are discussed. This technology involves the compression of air using base load electric power for storage in an underground storage medium. The air is subsequently released and allowed to pass through a turbine to generate electricity during periods of peak demand. The storage media considered most feasible are a mined hard rock cavern, a solution-mined cavern in a salt deposit, and a porous geologic formation (normally an aquifer) of suitable structure. The issues are discussed in four categories: regulatory issues common to most CAES facilities regardless of storage medium, regulatory issues applicable to particular CAES reservoir media, issues related to possible liability from CAES operations, and issues related to acquisition of appropriate property rights for CAES implementation. The focus is on selected federal regulation. Lesser attention is given to state and local regulation. (WHK)

  9. Advanced Reactor Technology -- Regulatory Technology Development Plan (RTDP)

    Energy Technology Data Exchange (ETDEWEB)

    Moe, Wayne Leland [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    This DOE-NE Advanced Small Modular Reactor (AdvSMR) regulatory technology development plan (RTDP) will link critical DOE nuclear reactor technology development programs to important regulatory and policy-related issues likely to impact a “critical path” for establishing a viable commercial AdvSMR presence in the domestic energy market. Accordingly, the regulatory considerations that are set forth in the AdvSMR RTDP will not be limited to any one particular type or subset of advanced reactor technology(s) but rather broadly consider potential regulatory approaches and the licensing implications that accompany all DOE-sponsored research and technology development activity that deal with commercial non-light water reactors. However, it is also important to remember that certain “minimum” levels of design and safety approach knowledge concerning these technology(s) must be defined and available to an extent that supports appropriate pre-licensing regulatory analysis within the RTDP. Final resolution to advanced reactor licensing issues is most often predicated on the detailed design information and specific safety approach as documented in a facility license application and submitted for licensing review. Because the AdvSMR RTDP is focused on identifying and assessing the potential regulatory implications of DOE-sponsored reactor technology research very early in the pre-license application development phase, the information necessary to support a comprehensive regulatory analysis of a new reactor technology, and the resolution of resulting issues, will generally not be available. As such, the regulatory considerations documented in the RTDP should be considered an initial “first step” in the licensing process which will continue until a license is issued to build and operate the said nuclear facility. Because a facility license application relies heavily on the data and information generated by technology development studies, the anticipated regulatory

  10. Advanced Reactor Technologies - Regulatory Technology Development Plan (RTDP)

    Energy Technology Data Exchange (ETDEWEB)

    Moe, Wayne L.

    2017-08-23

    This DOE-NE Advanced Small Modular Reactor (AdvSMR) regulatory technology development plan (RTDP) will link critical DOE nuclear reactor technology development programs to important regulatory and policy-related issues likely to impact a “critical path” for establishing a viable commercial AdvSMR presence in the domestic energy market. Accordingly, the regulatory considerations that are set forth in the AdvSMR RTDP will not be limited to any one particular type or subset of advanced reactor technology(s) but rather broadly consider potential regulatory approaches and the licensing implications that accompany all DOE-sponsored research and technology development activity that deal with commercial non-light water reactors. However, it is also important to remember that certain “minimum” levels of design and safety approach knowledge concerning these technology(s) must be defined and available to an extent that supports appropriate pre-licensing regulatory analysis within the RTDP. Final resolution to advanced reactor licensing issues is most often predicated on the detailed design information and specific safety approach as documented in a facility license application and submitted for licensing review. Because the AdvSMR RTDP is focused on identifying and assessing the potential regulatory implications of DOE-sponsored reactor technology research very early in the pre-license application development phase, the information necessary to support a comprehensive regulatory analysis of a new reactor technology, and the resolution of resulting issues, will generally not be available. As such, the regulatory considerations documented in the RTDP should be considered an initial “first step” in the licensing process which will continue until a license is issued to build and operate the said nuclear facility. Because a facility license application relies heavily on the data and information generated by technology development studies, the anticipated regulatory

  11. FORUM ISSUES IN THE ENFORCEMENT OF REGULATORY ...

    African Journals Online (AJOL)

    1 A Nigerian public company is a corporate entity that is incorporated in accordance .... of self-regulatory organisations in most financial markets who thus far have ...... the ISA, 2007, to the fundamental issue in the appeal, which is whether a.

  12. Regulatory issues in accreditation of toxicology laboratories.

    Science.gov (United States)

    Bissell, Michael G

    2012-09-01

    Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulated environment. This article outlines major US legal/regulatory issues and requirements relevant to accreditation of toxicology laboratories (state and local regulations are not covered in any depth). The most fundamental regulatory distinction involves the purposes for which the laboratory operates: clinical versus nonclinical. The applicable regulations and the requirements and options for operations depend most basically on this consideration, with clinical toxicology laboratories being directly subject to federal law including mandated options for accreditation and forensic toxicology laboratories being subject to degrees of voluntary or state government–required accreditation.

  13. 2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 2 - hybrid LBA/LCMS and input from regulatory agencies).

    Science.gov (United States)

    Ackermann, Brad; Neubert, Hendrik; Hughes, Nicola; Garofolo, Fabio; Abberley, Lee; Alley, Stephen C; Brown-Augsburger, Patricia; Bustard, Mark; Chen, Lin-Zhi; Heinrich, Julia; Katori, Noriko; Kaur, Surinder; Kirkovsky, Leo; Laterza, Omar F; Le Blaye, Olivier; Lévesque, Ann; Santos, Gustavo Mendes Lima; Olah, Timothy; Savoie, Natasha; Skelly, Michael; Spitz, Susan; Szapacs, Matthew; Tampal, Nilufer; Wang, Jian; Welink, Jan; Wieling, Jaap; Haidar, Sam; Vinter, Stephen; Whale, Emma; Witte, Bärbel

    2015-12-01

    The 2015 9th Workshop on Recent Issues in Bioanalysis (9th WRIB) took place in Miami, Florida with participation of over 600 professionals from pharmaceutical and biopharmaceutical companies, biotechnology companies, contract research organizations and regulatory agencies worldwide. It is once again a 5-day week long event - a full immersion bioanalytical week - specifically designed to facilitate sharing, reviewing, discussing and agreeing on approaches to address the most current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS, LBA approaches including the focus on biomarkers and immunogenicity. This 2015 White Paper encompasses recommendations that emerged from the extensive discussions held during the workshop, and is aimed at providing the bioanalytical community with key information and practical solutions on topics and issues addressed, in an effort to advance scientific excellence, improve quality and deliver better regulatory compliance. Due to its length, the 2015 edition of this comprehensive White Paper has been divided into three parts. Part 2 covers the recommendations for hybrid LBA/LCMS and regulatory agencies' inputs. Part 1 (small molecule bioanalysis using LCMS) and Part 3 (large molecule bioanalysis using LBA, biomarkers and immunogenicity) will be published in volume 7 of Bioanalysis, issues 22 and 24, respectively.

  14. Technology and technology transfer: some basic issues

    OpenAIRE

    Shamsavari, Ali; Adikibi, Owen; Taha, Yasser

    2002-01-01

    This paper addresses various issues relating to technology and transfer of technology such as technology and society, technology and science, channels and models of technology transfer, the role of multinational companies in transfer of technology, etc. The ultimate objective is to pose the question of relevance of some existing models and ideas like technological independence in an increasingly globalised world economy.

  15. Summary Report Panel 2: Regulatory Issues.

    Science.gov (United States)

    Johnson, Craig; Dolman, Sarah

    2016-01-01

    The Effects of Noise on Aquatic Life 2013 Conference convened four panels to discuss specific topics related to the effects of anthropogenic noise on aquatic ecosystems. The second of these four panels, the Regulatory Issues Panel, brought together several different perspectives: representatives of agencies responsible for regulating activities that introduce anthropogenic noise into aquatic ecosystems: representatives of the regulated industries, agencies, and consultancies that advise regulators and regulated industries; and nongovernmental organizations and other stakeholders with an interest in anthropogenic noise. The goal of the panel was to help develop a more productive relationship between these groups.

  16. Wind technology issues

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Antoni; Prats, Pep [Ecotecnia S.C.C.L., Barcelona (Spain)

    1999-01-01

    The paper focuses on the main trends of the technology behind the present wind energy applications. The technology characteristics and main challenges are analysed. The important links between political decisions and the development to date of wind turbines signal a direction for forecasting future tendencies and the possible technical characteristics of future turbines. (Author)

  17. Security issues of new innovative payments and their regulatory challenges

    NARCIS (Netherlands)

    Kasiyanto, Safari; Gabriella, Gimigliano

    2016-01-01

    Kasiyanto discusses how the security issues of M-payments and Bitcoin as new forms of innovative payments challenge the existing EU regulatory frameworks, and whether the proposed regulatory frameworks suffice to address such challenges. The regulatory frameworks Kasiyanto discusses mainly focus on

  18. Security issues of new innovative payments and their regulatory challenges

    NARCIS (Netherlands)

    Kasiyanto, Safari; Gabriella, Gimigliano

    2016-01-01

    Kasiyanto discusses how the security issues of M-payments and Bitcoin as new forms of innovative payments challenge the existing EU regulatory frameworks, and whether the proposed regulatory frameworks suffice to address such challenges. The regulatory frameworks Kasiyanto discusses mainly focus on

  19. Abandoning pipelines working group regulatory issues

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The history of hydrocarbon development in Louisiana and off its coast is one of the interdependence of technological innovation, entrepreneurial risk-taking, resource management, judicial decisions, legislation, marketing, employee good will, infrastructure and support services, coupled with favorable geologic structures that made early exploration and development relatively easy. Mariners sailing off the coast of Louisiana and Texas in the 1600`s recorded one of the earliest known natural oil seeps. They shrugged it off as unimportant, as there was no market for the substance they witnessed. The seepage, however, provided a tiny clue to the vast storehouse of hydrocarbons trapped in the earth`s crust extending from the uplands, through Louisiana`s swamps and marshes, and into the subaqueous habitats of the Gulf of Mexico-the world`s ninth largest body of water. In all cases, each move into a new geographic province required considerable change in operation philosophy and in the science supporting the exploration and development activity. As technology changed, or was developed to meet the industry`s needs, new frontiers were explored. However, with time-as is the case with any nonrenewable resource-fields and wells lost their productive life. They had to be abandoned. In fact, the Minerals Management Service suggests that within the next 10 years the offshore industry will remove 150 platforms per year, or nearly half of the current number of production units. The industry will be asked to dispose of nearly one unit every 2.4 days. If this is the case, abandonment issues are going to continue to surface.

  20. Legal and regulatory issues affecting aquifer thermal energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Hendrickson, P.L.

    1981-10-01

    This document updates and expands the report with a similar title issued in October 1980. This document examines a number of legal and regulatory issues that potentially can affect implementation of the aquifer thermal energy storage (ATES) concept. This concept involves the storage of thermal energy in an underground aquifer until a later date when it can be effectively utilized. Either heat energy or chill can be stored. Potential end uses of the energy include district space heating and cooling, industrial process applications, and use in agriculture or aquaculture. Issues are examined in four categories: regulatory requirements, property rights, potential liability, and issues related to heat or chill delivery.

  1. Exploring the ethical and regulatory issues in pragmatic clinical trials.

    Science.gov (United States)

    Califf, Robert M; Sugarman, Jeremy

    2015-10-01

    The need for high-quality evidence to support decision making about health and health care by patients, physicians, care providers, and policy-makers is well documented. However, serious shortcomings in evidence persist. Pragmatic clinical trials that use novel techniques including emerging information and communication technologies to explore important research questions rapidly and at a fraction of the cost incurred by more "traditional" research methods promise to help close this gap. Nevertheless, while pragmatic clinical trials can bridge clinical practice and research, they may also raise difficult ethical and regulatory challenges. In this article, the authors briefly survey the current state of evidence that is available to inform clinical care and other health-related decisions and discuss the potential for pragmatic clinical trials to improve this state of affairs. They then propose a new working definition for pragmatic research that centers upon fitness for informing decisions about health and health care. Finally, they introduce a project, jointly undertaken by the National Institutes of Health Health Care Systems Research Collaboratory and the National Patient-Centered Clinical Research Network (PCORnet), which addresses 11 key aspects of current systems for regulatory and ethical oversight of clinical research that pose challenges to conducting pragmatic clinical trials. In the series of articles commissioned on this topic published in this issue of Clinical Trials, each of these aspects is addressed in a dedicated article, with a special focus on the interplay between ethical and regulatory considerations and pragmatic clinical research aimed at informing "real-world" choices about health and health care.

  2. Policy and Regulatory Issues for Underground Coal Gasification in India

    Science.gov (United States)

    Singh, Sunil K.

    2017-07-01

    Underground coal gasification (UCG) is in its nascent stage of development. Most of the projects are in the nature of pilot projects. UCG technology requires acceptance in general commercial framework as it matures with the progress of time. Policy and regulatory framework, therefore, is considered here only in the expectation that UCG technology may finally be rolled out sooner than later. India is actively pursuing consultations with major countries which have recorded successes in implementing UCG technology in varying measures. In this background, the discussion on policy and regulatory framework is essentially an effort to capture the broad outline of the understanding of the UCG process in a regulatory construct as compared with other regulatory regimes of similar nature.

  3. Regulatory Promotion of Emergent CCS Technology

    Energy Technology Data Exchange (ETDEWEB)

    Davies, Lincoln; Uchitel, Kirsten; Johnson, David

    2014-01-01

    Despite the growing inevitability of climate change and the attendant need for mitigation strategies, carbon capture and sequestration (CCS) has yet to gain much traction in the United States. Recent regulatory proposals by the U.S. Environmental Protection Agency (EPA), limited in scope to new-build power plants, represent the only significant policy initiative intended to mandate diffusion of CCS technology. Phase I of this Project assessed barriers to CCS deployment as prioritized by the CCS community. That research concluded that there were four primary barriers: (1) cost, (2) lack of a carbon price, (3) liability, and (4) lack of a comprehensive regulatory regime. Phase II of this Project, as presented in this Report, assesses potential regulatory models for CCS and examines where those models address the hurdles to diffusing CCS technology identified in Phase I. It concludes (1) that a CCS-specific but flexible standard, such as a technology performance standard or a very particular type of market-based regulation, likely will promote CCS diffusion, and (2) that these policies cannot work alone, but rather, should be combined with other measures, such as liability limits and a comprehensive CCS regulatory regime.

  4. A study on the regulatory approach of major technical issues

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Keun Sun; Choi, J. T.; Kim, I. J. [Sunmoon Univ., Asan (Korea, Republic of); Lee, S. H.; Baek, W. P.; Yang, S. H. [Korea Association for Nuclear Technology, Taejon (Korea, Republic of)

    1998-06-15

    This project is to provide the regulatory direction of 4 major technical issues for the Korean Next Generation Reactors, which are parts of major technical issues resulted from the safety regulation R and D on the KNGR. The outstanding results are as follows : reliability of risk significant SSCs established during design stage must be maintained through the operating life of the plant, currently used classification method of plant conditions and safety requirement were reviewed, and a quantitative classification method is needed to be developed further, the basic regulatory directions are proposed for multiple failures such as SBO, TLOFW, multiple SGTR and ATWS, safety requirements are proposed for survivability/availability of severe accident mitigation design features by 5 items if basic requirements, selection of initial event, identification of available equipment and instruments, identification of environmental conditions and verification methods.

  5. 3D Bioprinting Technology: Scientific Aspects and Ethical Issues.

    Science.gov (United States)

    Patuzzo, Sara; Goracci, Giada; Gasperini, Luca; Ciliberti, Rosagemma

    2017-06-28

    The scientific development of 3D bioprinting is rapidly advancing. This innovative technology involves many ethical and regulatory issues, including theoretical, source, transplantation and enhancement, animal welfare, economic, safety and information arguments. 3D bioprinting technology requires an adequate bioethical debate in order to develop regulations in the interest both of public health and the development of research. This paper aims to initiate and promote ethical debate. The authors examine scientific aspects of 3D bioprinting technology and explore related ethical issues, with special regard to the protection of individual rights and transparency of research. In common with all new biotechnologies, 3D bioprinting technology involves both opportunities and risks. Consequently, several scientific and ethical issues need to be addressed. A bioethical debate should be carefully increased through a multidisciplinary approach among experts and also among the public.

  6. ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH

    Science.gov (United States)

    ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH, designed to stimulate dialogue on ethical and regulatory issues in cancer research and promote awareness of developing policies and best practices.

  7. Population Issues. Resources in Technology.

    Science.gov (United States)

    Technology Teacher, 1991

    1991-01-01

    Presents information about the problems caused by increasing population. Discusses the environmental impact and the ways that technology can be used to solve problems of overpopulation. Includes possible student outcomes and a student quiz. (JOW)

  8. Population Issues. Resources in Technology.

    Science.gov (United States)

    Technology Teacher, 1991

    1991-01-01

    Presents information about the problems caused by increasing population. Discusses the environmental impact and the ways that technology can be used to solve problems of overpopulation. Includes possible student outcomes and a student quiz. (JOW)

  9. A study on the regulatory approach of major technical issues

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Keun Sun; Oh, S. H.; Kang, H. J.; Kim, G. S. [Sunmoon Univ., Asan (Korea, Republic of); Lee, S. H.; Baek, W. P.; Yang, S. H.; Jeong, Y. H. [Korea Association for Nuclear Technology, Taejon (Korea, Republic of)

    1999-02-15

    This project is to provide the regulatory direction of 4 major technical issues for the Korean Next Generation Reactors, which are parts of major technical issues resulted from the safety regulation R and D on the KNGR. The outstanding results are are as follows : related to the classification and acceptance criteria of plant conditions, currently used classification and safety requirement were reviewed and regulatory direction was proposed. Among multiple failures, it is identified that SBO, TLOFW, multiple SGTR and ATWS are basically to be considered for additional requirements for advanced reactors. This study reviewed risk aspects, design consideration, and trends of safety requirements, and proposed fundamental safety requirements to be applied for KNGR. Multiple steam generator tube failure is a significant safety concern because of the possibility of release of radionuclides to the environment through containment bypass. Proposed safety requirement for this event can be categorized mainly as analysis requirement, design evaluation requirement and PSA requirement; For protection of containment failure, a reasonable safety position is necessary through and integrated review of possibility of severe accident occurrence, effects of sever accident mitigation features and cost effects of these design features. With this consideration safety requirements developed are the analysis requirement, provision of protective measures and survivability/availability of protective measures.

  10. Technology Transfer Issues and a New Technology Transfer Model

    Science.gov (United States)

    Choi, Hee Jun

    2009-01-01

    The following are major issues that should be considered for efficient and effective technology transfer: conceptions of technology, technological activity and transfer, communication channels, factors affecting transfer, and models of transfer. In particular, a well-developed model of technology transfer could be used as a framework for…

  11. Possible future environmental issues for fossil fuel technologies. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Attaway, L.D.

    1979-07-01

    The work reported here was carried out for the Department of Energy's Office of Fossil Energy to identify and assess 15 to 20 major environmental issues likely to affect the implementation of fossil energy technologies between 1985 and 2000. The energy technologies specifically addressed are: oil recovery and processing; gas recovery and processing; coal liquefaction; coal gasification (surface); in situ coal gasification; direct coal combustion; advanced power systems; magnetohydrodynamics; surface oil shale retorting; and true and modified in situ oil shale retorting. Environmental analysis of these technologies included, in addition to the main processing steps, the complete fuel cycle from resource extraction to end use. The 16 environmental issues identified as those most likely for future regulatory actions and the main features of, and the possible regulatory actions associated with, each are as follows: disposal of solid waste from coal conversion and combustion technologies; water consumption by coal and oil shale conversion technologies; siting of coal conversion facilities; the carbon dioxide greenhouse effect; emission of polycyclic organic matter (POM); impacts of outer continental shelf (OCS) oil development; emission of trace elements; groundwater contamination; liquefied natural gas (LNG), safety and environmental factors; underground coal mining - health and safety; fugitive emissions from coal gasification and liquefaction - health and safety; boomtown effects; emission of fine particulates from coal, oil and oil shale technologies; emission of radioactivity from the mining and conversion of coal; emission of nitrogn oxides; and land disturbance from surface mining. (LTN)

  12. Regulatory Issues Associated with Preharvest Food Safety: European Union Perspective.

    Science.gov (United States)

    Alban, Lis

    2016-10-01

    Free movement of safe and wholesome food is an essential aspect of any society. This article contains an updated description of the regulatory issues associated with preharvest food safety within the European Union. Salmonella, Campylobacter, Trichinella, antimicrobial resistance, and bovine spongiform encephalopathy are dealt with in detail. Moreover, Cysticercus bovis/Taenia saginata, Toxoplasma, Yersinia, verotoxigenic/shigatoxigenic Escherichia coli, Listeria, and foodborne viruses are briefly covered. The article describes how the focus in the European Union is changing to involve a supply chain view with a focus on cost-effectiveness. The precautionary principle-as well as the use of private standards as an instrument to ensure compliance-is dealt with. In addition, actions in the pipeline are presented and discussed.

  13. Science, Technology, & Human Values. Issue No. 26.

    Science.gov (United States)

    Shelanski, Vivien B., Ed.; La Follette, Marcel C., Ed.

    This issue contains articles on the recombinant DNA controversy, the ethical principles of scientific institutions, and the effect of disaster novels on public opinion and technology assessment, as well as a guide to funding for science, technology and values projects, and a bibliography on professional ethics. In addition, 14 pages of news items…

  14. Addressing Issues Related to Technology and Engineering

    Science.gov (United States)

    Technology Teacher, 2008

    2008-01-01

    This article presents an interview with Michael Hacker and David Burghardt, codirectors of Hoftra University's Center for Technological Literacy. Hacker and Burghardt address issues related to technology and engineering. They argue that teachers need to be aware of the problems kids are facing, and how to present these problems in an engaging…

  15. RFID Technologies : emerging issues and challenges

    NARCIS (Netherlands)

    Lieshout, M.J. van; Kool, L.

    2007-01-01

    In this paper we will present the results of a technology and policy assessment we have performed on emerging issues and policy challenges of RFID technologies. RFID is a basic component of the future internet of things. A balanced view on opportunities and threats, on drivers and barriers is needed

  16. Teaching Science and Technology Issues: Curriculum Perspectives.

    Science.gov (United States)

    Kumar, David

    1997-01-01

    Discusses problems in teaching science and technology from a societal perspective if not handled with prudence. The misapplication of scientific and technological knowledge in Nazi Germany in World War II is explored in particular. Suggests that an issue-oriented education is needed to help students gain an overall understanding of scientific…

  17. Health care technology as a policy issue

    NARCIS (Netherlands)

    Banta, H.D.

    1994-01-01

    Health care technology has become an increasingly visible issue in many countries, primarily because of the rising costs of health care. In addition, many questions concerning quality of care are being raised. Health care technology assessment has been seen as an aid in addressing questions

  18. RFID Technologies : emerging issues and challenges

    NARCIS (Netherlands)

    Lieshout, M.J. van; Kool, L.

    2007-01-01

    In this paper we will present the results of a technology and policy assessment we have performed on emerging issues and policy challenges of RFID technologies. RFID is a basic component of the future internet of things. A balanced view on opportunities and threats, on drivers and barriers is needed

  19. Environmental issues affecting clean coal technology deployment

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.J. [Electric Power Research Inst., Palo Alto, CA (United States)

    1997-12-31

    The author outlines what he considers to be the key environmental issues affecting Clean Coal Technology (CCT) deployment both in the US and internationally. Since the international issues are difficult to characterize given different environmental drivers in various countries and regions, the primary focus of his remarks is on US deployment. However, he makes some general remarks, particularly regarding the environmental issues in developing vs. developed countries and how these issues may affect CCT deployment. Further, how environment affects deployment depends on which particular type of clean coal technology one is addressing. It is not the author`s intention to mention many specific technologies other than to use them for the purposes of example. He generally categorizes CCTs into four groups since environment is likely to affect deployment for each category somewhat differently. These four categories are: Precombustion technologies such as coal cleaning; Combustion technologies such as low NOx burners; Postcombustion technologies such as FGD systems and postcombustion NOx control; and New generation technologies such as gasification and fluidized bed combustion.

  20. Regulatory policy issues and the Clean Air Act: Issues and papers from the state implementation workshops

    Energy Technology Data Exchange (ETDEWEB)

    Rose, K. [ed.; Burns, R.E.

    1993-07-01

    The National Regulatory Research Institute (NRRI), with funding from the US Environmental Protection Agency (EPA) and the US Department of Energy (DOE), conducted four regional workshops` on state public utility commission implementation of the Clean Air Act Amendments of 1990 (CAAA). The workshops had four objectives: (1) to discuss key issues and concerns on CAAA implementation, (2) to encourage a discussion among states on issues of common interests, (3) to attempt to reach consensus, where possible, on key issues, and (4) to provide the workshop participants with information and materials to assist in developing state rules, orders, and procedures. From the federal perspective, a primary goal was to ensure that workshop participants return to their states with a comprehensive background and understanding of how state commission actions may affect implementation of the CAAA and to be able to provide guidance to their jurisdictional utilities. It was hoped that this would reduce some of the uncertainty utilities face and assist in the development of an efficient allowance market. This report is divided into two main sections. In Section II, eleven principal issues are identified and discussed. These issues were chosen because they were either the most frequently discussed or they were related to the questions asked in response to the speakers` presentations. This section does not cover all the issues relevant to state implementation nor all the issues discussed at the workshops; rather, Section II is intended to provide an overview of the,planning, ratemaking, and multistate issues. Part III is a series of workshop papers presented by some of the speakers. Individual papers have been cataloged separately.

  1. Debatable Issues of Regulatory Policy of Russian Nanoindustry

    Directory of Open Access Journals (Sweden)

    Frolov Daniil Petrovich

    2015-05-01

    Full Text Available The article studies the debatable issues of regulatory policy in the sphere of nanoindustry. The nanotech industry has interindustry character that is caused by interdisciplinarity of a nanoscience therefore it is necessary to recognize objectively impossible exact definition of its branch structure. As a result of terminological uncertainty, the state support and regulation of nanotech industry is a difficult process. The substantial expansionism of the term “nanotechnology” and metaphorism of the concept “nanoindustry” is reasoned. The need of creating more detailed classification (by 1-2 orders of nanotechnologies and allocation of at least three subindustries of nanotech industry is proved. The deficiency of convergent orientation of policy of regulation of the Russian hi-tech industries is revealed. The conceptual discrepancy of nanoindustrial policy of the Russian Federation combining elements of traditional policy of import substitution and new industrial policy is shown. The expediency of transition from universal policy of nanoindustry regulation to the development of a package of the segment-focused strategies of development of different types of nanotechnologies and the nanotechnological activities is proved. The special attention is paid to a safety control problem (combination of obligatory certification and voluntary marking of nanoproduction, strengthening the role of nanotech industry self-regulation and active integration of stakeholders into the system of strategic planning.

  2. Science and technology review, September 1998 issue

    Energy Technology Data Exchange (ETDEWEB)

    Smart, J

    1998-09-01

    This issue focuses on monitoring the Comprehensive Test Ban Treaty. A feature article on the history of the Laboratory is also included. Other articles highlight X-ray laser technology and the ground testing of microsatellites that emulates the free-floating environment of actual space flight

  3. Technology Issues in Indian Country Today.

    Science.gov (United States)

    Warner, Linda Sue

    1998-01-01

    Examines legal and ethical issues related to Internet use and use of other technologies in Native American communities. Discusses conflict between federal telecommunications policy and the principles of tribal sovereignty, cultural appropriation, intellectual property rights, gatekeeping to limit access to traditional knowledge, and effects of…

  4. Technology and the issues facing nursing assessment.

    Science.gov (United States)

    Ansell, Helen; Meyer, Alannah; Thompson, Shona

    This article describes an investigation into the use of technology and the issues nurses face undertaking nursing assessment. It reports qualitative, descriptive research involving interviews with ten ward nurses from three hospitals in New Zealand. Thematic analysis of the data revealed three key issues: the impact of technology, the influence of early warning systems and nurse autonomy. Results show how clinical decision making around nursing assessment is influenced by technology and the Early Warning Score. These clinical decisions may not always be informed by critical thinking in complex healthcare environments. The article concludes that nurse autonomy, while supported and endorsed in theory, is frequently in conflict with hospital risk-management policies and the use of prescriptive algorithms.

  5. Innovation under Regulatory Uncertainty: Evidence from Medical Technology.

    Science.gov (United States)

    Stern, Ariel Dora

    2017-01-01

    This paper explores how the regulatory approval process affects innovation incentives in medical technologies. Prior studies have found early mover regulatory advantages for drugs. I find the opposite for medical devices, where pioneer entrants spend 34 percent (7.2 months) longer than follow-on entrants in regulatory approval. Back-of-the- envelope calculations suggest that the cost of a delay of this length is upwards of 7 percent of the total cost of bringing a new high-risk device to market. Considering potential explanations, I find that approval times are largely unrelated to technological novelty, but are meaningfully reduced by the publication of objective regulatory guidelines. Finally, I consider how the regulatory process affects small firms' market entry patterns and find that small firms are less likely to be pioneers in new device markets, a fact consistent with relatively higher costs of doing so for more financially constrained firms.

  6. Regulatory Challenges for Cartilage Repair Technologies.

    Science.gov (United States)

    McGowan, Kevin B; Stiegman, Glenn

    2013-01-01

    In the United States, few Food and Drug Administration (FDA)-approved options exist for the treatment of focal cartilage and osteochondral lesions. Developers of products for cartilage repair face many challenges to obtain marketing approval from the FDA. The objective of this review is to discuss the necessary steps for FDA application and approval for a new cartilage repair product. FDA Guidance Documents, FDA Panel Meetings, scientific organization recommendations, and clinicaltrials.gov were reviewed to demonstrate the current thinking of FDA and the scientific community on the regulatory process for cartilage repair therapies. Cartilage repair therapies can receive market approval from FDA as medical devices, drugs, or biologics, and the specific classification of product can affect the nonclinical, clinical, and regulatory strategy to bring the product to market. Recent FDA guidance gives an outline of the required elements to bring a cartilage repair product to market, although these standards are often very general. As a result, companies have to carefully craft their study patient population, comparator group, and clinical endpoint to best showcase their product's attributes. In addition, regulatory strategy and manufacturing process validation need to be considered early in the clinical study process to allow for timely product approval following the completion of clinical study. Although the path to regulatory approval for a cartilage repair therapy is challenging and time-consuming, proper clinical trial planning and attention to the details can eventually save companies time and money by bringing a product to the market in the most expeditious process possible.

  7. Telecare technologies and isolation: some ethical issues

    Directory of Open Access Journals (Sweden)

    Eccles A

    2015-05-01

    Full Text Available Andrew Eccles School of Social Work & Social Policy, University of Strathclyde, Glasgow, UK Abstract: Telecare technologies involve the remote monitoring of patients who have health, rehabilitation or social needs. These technologies, although deployed unevenly in developed countries, represent a shift in the ways in which care is practiced. Research on the consequences of this shift away from more traditional "hands-on" care has focused primarily on quantitative measurement (for example cost savings with less attention paid to how recipients themselves experience these new care practices. This paper discusses two aspects of telecare technologies which are under researched; the potential for loneliness which may arise as a result of the use of these technologies, and the ethical issues raised by this. The primary locus of the discussion is the UK, where a major public policy shift towards telecare is under way and where telecare research based on randomized control trials has been particularly well funded by the government. The discussion concludes that there is indeed the potential for loneliness, a condition increasingly recognized as a significant factor in reducing overall health and well-being, in the use of these technologies. The ethical implications of this are not being sufficiently considered, in part because the ethical frameworks in use do not adequately address the issue of loneliness itself, given their bio-medical, rather than relational focus. The paper suggests two ways of redressing this. First, the addition of approaches to ethics other than bio-medical – particularly those with a relational and contextual focus – or greater exploration of how the two approaches might interact. Second, it suggests that a paradigm shift towards solutions other than technology-based care is overdue. This shift would not underplay the importance of technological contributions to care needs. It would, however, be an argument to suggest we

  8. A prudential regulatory issue at the heart of Solvency II

    NARCIS (Netherlands)

    Perotti, E.; Danielsson, J.; de Jong, F.; Laux, C.; Laeven, R.; Wüthrich, M.

    2011-01-01

    A delicate regulatory question is under consideration on the capital (reserve) requirements at the heart of Solvency II (the insurance industry equivalent of Basel III), which is scheduled to come into effect by 2013. This decision will have implications for both regulation of insurers and for

  9. Steam generators regulatory practices and issues in Spain

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza, C.; Castelao, C.; Ruiz-Colino, J.; Figueras, J.M. [CSN, Madrid (Spain)

    1997-02-01

    This paper presents the actual status of Spanish Steam Generator tubes, actions developed by PWR plant owners and submitted to CSN, and regulatory activities related to tube degradation mechanisms analysis; NDT tube inspection techniques; tube, tubesheet and TSPs integrity studies; tube plugging/repair criteria; preventive and corrective measures including whole SGs replacement; tube leak measurement methods and other operational aspects.

  10. A prudential regulatory issue at the heart of Solvency II

    NARCIS (Netherlands)

    Perotti, E.; Danielsson, J.; de Jong, F.; Laux, C.; Laeven, R.; Wüthrich, M.

    2011-01-01

    A delicate regulatory question is under consideration on the capital (reserve) requirements at the heart of Solvency II (the insurance industry equivalent of Basel III), which is scheduled to come into effect by 2013. This decision will have implications for both regulation of insurers and for macro

  11. Unconventional dentistry: Part III. Legal and regulatory issues.

    Science.gov (United States)

    Goldstein, B H

    2000-10-01

    This is the third in a series of 5 articles providing a contemporary overview and introduction to unconventional dentistry (UD) and its correlation to unconventional medicine (UM). UD presents issues of dental quackery, fraud and malpractice, and it also engenders professional concerns about public protection and professional risks. Case reports illustrate numerous issues. The reader is encouraged to evaluate the cases for problems related to malpractice, fraud, ethics, behaviours and professionalism. A discussion of ethical issues is beyond the scope of this paper.

  12. 75 FR 27028 - Joint CFTC-SEC Advisory Committee on Emerging Regulatory Issues

    Science.gov (United States)

    2010-05-13

    ... issues of mutual concern and their effect on the CFTC's and SEC's statutory responsibilities. Subjects to... committee will work to develop clear and specific goals toward identifying and addressing emerging regulatory risks, protecting investors and customers, and furthering regulatory harmonization, and...

  13. Safety and regulatory issues regarding stem cell therapies: one clinic's perspective.

    Science.gov (United States)

    Centeno, Christopher J; Bashir, Jamil

    2015-04-01

    Stem cells therapies have been in preclinical development for the past 2 decades. A rapidly evolving regulatory landscape has restrained many of these technologies from advancing from the bench to the bedside. Although the large-scale clinical safety of stem cell therapies remains to be fully tested, the total number of patients who have safely received these therapies is large and growing. Prima facie evidence would dictate that certain types of cell therapy are likely safer than others. Understanding the current regulation regarding stem cells involves a discussion of their safety profile, as the 2 issues are closely intertwined. Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  14. Private pension funds in Hungary : early performance and regulatory issues

    OpenAIRE

    Vittas, Dimitri

    1996-01-01

    Despite the limited scope resulting from the high payroll taxes for the compulsory, unfunded public pillar in Hungary's pensions system, the early voluntary private pensions fund performance has been encouraging. Investment returns have been well above the inflation rate and participation has expanded rapidly. However, the sector is highly fragmented and regulatory weaknesses exist: no compulsory use of custodian and licensed asset managers; use of book values and cashflow accounting rather t...

  15. U.S. perspective on mycotoxin regulatory issues.

    Science.gov (United States)

    Park, Douglas L; Troxell, Terry C

    2002-01-01

    Control programs set up by the Food and Drug Administration (FDA) for aflatoxin, an unavoidable natural contaminant produced by specific molds that invade a number of feedstuffs and basic foods, provide an example of forces that affect risk assessment and management strategies by a regulatory agency. More recently, on an international scale, efforts to establish international food standards for fumonisin, deoxynivalenol, ochratoxin A, zearalenone, and patulin, as well as for aflatoxin, demonstrate the complexity of developing regulations and/or standards designed to protect consumer health and ensure fair trade practices on a global scale. Current FDA regulations for aflatoxins address public health concerns for potential contamination in basic foods, residues in milk, and animal feeds for numerous commodities and applications. Regulatory limits, sampling and analytical procedures, decontamination and/or diversion to less risk uses for contaminated product are components of mycotoxin control programs. Current efforts by FDA to establish regulatory controls for deoxynivalenol, fumonisin, and patulin add further insight on the role that safety and risk assessment procedures play in the development of action levels and advisories for mycotoxins.

  16. Legal, privacy, security, access and regulatory issues in cloud computing

    CSIR Research Space (South Africa)

    Dlodlo, N

    2011-04-01

    Full Text Available around the issues of policy interventions, standards, privacy and data protection, traffic and congestion management, business continuity planning, security and regulation. This research is an advancement of knowledge in that field and is meant...

  17. Legal, regulatory & institutional issues facing distributed resources development

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This report describes legal, regulatory, and institutional considerations likely to shape the development and deployment of distributed resources. It is based on research co-sponsored by the National Renewable Energy Laboratory (NREL) and four investor-owned utilities (Central & South West Services, Cinergy Corp., Florida Power Corporation, and San Diego Gas & Electric Company). The research was performed between August 1995 and March 1996 by a team of four consulting firms experienced in energy and utility law, regulation, and economics. It is the survey phase of a project known as the Distributed Resources Institutional Analysis Project.

  18. Overview of Variable Renewable Energy Regulatory Issues: A Clean Energy Regulators Initiative Report

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.; Cox, S.

    2014-05-01

    This CERI report aims to provide an introductory overview of key regulatory issues associated with the deployment of renewable energy -- particularly variable renewable energy (VRE) sources such wind and solar power. The report draws upon the research and experiences from various international contexts, and identifies key ideas that have emerged from the growing body of VRE deployment experience and regulatory knowledge. The report assumes basic familiarity with regulatory concepts, and although it is not written for a technical audience, directs the reader to further reading when available. VRE deployment generates various regulatory issues: substantive, procedural, and public interest issues, and the report aims to provide an empirical and technical grounding for all three types of questions as appropriate.

  19. TANK FARM REMEDIATION TECHNOLOGY DEVELOPMENT PROJECT AN EXERCISE IN TECHNICAL & REGULATORY COLLABORATION

    Energy Technology Data Exchange (ETDEWEB)

    JARAYSI, M.N.

    2007-01-08

    The Tank Farm Remediation Technology Development Project at the Hanford Site focuses on waste storage tanks, pipelines and associated ancillary equipment that are part of the C-200 single-shell tank (SST) farm system located in the C Tank Farm. The purpose of the project is to obtain information on the implementation of a variety of closure activities and to answer questions on technical, operational and regulatory issues associated with closure.

  20. Issues and regulatory requirements for the connection of wind generation

    Energy Technology Data Exchange (ETDEWEB)

    Gimenez Alvarez, J.M. [National University of San Juan (Argentina)], E-mail: jgimenez@unsj.edu.ar; Gomez Targarona, J.C. [National University of Rio Cuarto, Cordoba (Argentina). Electric Power Systems Protection Institute (IPSEP)], E-mail: jcgomez@ing.unrc.edu.ar

    2009-07-01

    Pollution problems such as greenhouse effect as well as the high value and volatility of fuel prices have forced and accelerated the development and use of renewable energy sources. In this work a complete revision of wind generation is presented. In the first part a brief history of the wind energy developments is detailed. Next, some commentaries related to the present and future state are made. Then, a revision of the modern structures of wind generation is realized. In fourth place it is included a brief comparison between small and big size turbines. Then, different types of energy storage are mentioned. Finally regulatory aspects are discussed, respect to the treatment of the technical problems. (author)

  1. Perchlorate Contamination of Drinking Water: Regulatory Issues and Legislative Actions

    Science.gov (United States)

    2008-10-16

    ppb standard in October 2007. Several states have issued health goals or advisory levels ranging from 1 ppb in Maryland (advisory level) and New Mexico ...Environmental Medicine, 2003, p. 1117. 6 Benjamin C. Blount, James L. Pirkle, et al., “Urinary Perchlorate and Thyroid Hormone Levels in Adolescent ...concern is that impairment of thyroid function in pregnant women can affect fetuses and nursing infants and can result in delayed development and

  2. Safety and Regulatory Issues of the Thorium Fuel Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Ade, Brian [ORNL; Worrall, Andrew [ORNL; Powers, Jeffrey [ORNL; Bowman, Steve [ORNL; Flanagan, George [ORNL; Gehin, Jess [ORNL

    2014-02-01

    Thorium has been widely considered an alternative to uranium fuel because of its relatively large natural abundance and its ability to breed fissile fuel (233U) from natural thorium (232Th). Possible scenarios for using thorium in the nuclear fuel cycle include use in different nuclear reactor types (light water, high temperature gas cooled, fast spectrum sodium, molten salt, etc.), advanced accelerator-driven systems, or even fission-fusion hybrid systems. The most likely near-term application of thorium in the United States is in currently operating light water reactors (LWRs). This use is primarily based on concepts that mix thorium with uranium (UO2 + ThO2), add fertile thorium (ThO2) fuel pins to LWR fuel assemblies, or use mixed plutonium and thorium (PuO2 + ThO2) fuel assemblies. The addition of thorium to currently operating LWRs would result in a number of different phenomenological impacts on the nuclear fuel. Thorium and its irradiation products have nuclear characteristics that are different from those of uranium. In addition, ThO2, alone or mixed with UO2 fuel, leads to different chemical and physical properties of the fuel. These aspects are key to reactor safety-related issues. The primary objectives of this report are to summarize historical, current, and proposed uses of thorium in nuclear reactors; provide some important properties of thorium fuel; perform qualitative and quantitative evaluations of both in-reactor and out-of-reactor safety issues and requirements specific to a thorium-based fuel cycle for current LWR reactor designs; and identify key knowledge gaps and technical issues that need to be addressed for the licensing of thorium LWR fuel in the United States.

  3. Healthcare providers constricted by financial, legislative, and regulatory issues.

    Science.gov (United States)

    Callahan, Marty

    2008-01-01

    The challenges facing the healthcare industry have created a chasm between the focus on quality of care and financial survival. More than 46.5 million Americans are uninsured, and another 16 million are underinsured with health insurance plans that leave patients unable to afford their portion of hospital charges. There are literally hundreds of solutions to assist hospitals in solving payor, self-pay, billing, and charity issues. Examples of solutions that are available include advanced analytics and modeling, automated decisioning and business rules engines, automated insurance eligibility verification, work flow tools, collection services, patient payment calculators, and many others. As the industry becomes more self-regulated and proactive, the pressure concerning business operations hopefully will diminish and hospitals can focus more on the delivery of care.

  4. Levothyroxine: therapeutic use and regulatory issues related to bioequivalence.

    Science.gov (United States)

    Wartofsky, Leonard

    2002-06-01

    Levothyroxine is the overwhelming choice of clinicians for the treatment of hypothyroidism and for the suppression of goitre and thyroid nodules in selected cases. The monitoring of serum levels of thyroid stimulating hormone is necessary for appropriate dosage adjustment of levothyroxine. Levothyroxine has a narrow therapeutic index: both underdosage (subclinical hypothyroidism) and excessive dosage (subclinical hyperthyroidism) are associated with adverse symptoms and pathophysiological effects and are to be avoided. The consequent necessity for careful titration of doses has had an impact on the issue of switchability, or bioequivalence, of the various marketed levothyroxine products. In this article, the basis for concern about currently accepted standards of the FDA for pharmacological bioequivalence are examined in the context of levothyroxine. The history and status of the recent request by the FDA for a new drug application for all levothyroxine products, and its impact on the market leader Synthroid, is also discussed.

  5. REGULATORY FUNDAMENTALS FOR IMPLEMENTATION OF INFORMATION TECHNOLOGY PROJECTS IN INDUSTRY

    Directory of Open Access Journals (Sweden)

    L. V. Gubich

    2016-01-01

    Full Text Available The article provides an overview of the existing regulatory basis for the development of IIST. The features of IT projects management and a brief description of methodological recommendations on implementation of IT projects of the State scientific and technical Program «Electronic enterprise resource planning (CALS-ERP-technology» for 2011–2015 are considered.

  6. Improving cancer treatment by addressing legislative and regulatory issues.

    Science.gov (United States)

    Olver, I

    2011-12-01

    To explore legislative and legal barriers to improving cancer treatment. The advocacy agenda of Cancer Council Australia was examined for key issues, and examples drawn from Australian law were presented at a conference entitled 'Legislate, regulate and litigate: legal perspectives on cancer prevention and treatment' at the University of Sydney. The introduction of electronic medical records and linkage of data sets from registries can produce very useful public health information, but could be a threat to individual privacy. The balance between these must underpin legislation and regulation. The new drug approval process must keep pace with developments such as targeted therapies, where tests to identify the presence of the target must also be approved simultaneously. The regulation of complementary and alternative medicines in cancer is challenging given their widespread use. In cancer research, it is vital that the important ethics and governance review process does not become a barrier to the ability to complete research in a reasonable time frame. A specific issue for future treatments and diagnostic tests that are to be targeted at genes and their products is to clarify gene patenting laws so that invention is rewarded, not mere discovery. The nature of the workforce will need to change to meet the treatment needs of an increasing incidence of cancer in an aging population, but regulation will need to ensure the maintenance of safety and quality standards. The flexibility of legislation and regulation to meet a rapidly changing environment is key to ensuring the timely adoption of new cancer treatments to improve cancer outcomes. Copyright © 2011. Published by Elsevier Ltd.. All rights reserved.

  7. A study on the regulatory approach of safety issues for Korean next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Keun Seon; Choi, Jeong Tae; Kim, In Joon [Sunmoon Univ., Asan (Korea, Republic of); Lee, Sang Hoon [Korea Association of Nuclear Technology, Taejon (Korea, Republic of); Kang, Gee Sik [Korea Power Engineering Co., Inc., Seoul (Korea, Republic of); Kim, Han Gon [Korea Electric Power Corporation, Seoul (Korea, Republic of); Park, Jae Uk; Kim, Yun Il; Yang, Soo Hyeong [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    1997-10-15

    The project aims to provide the regulatory direction of major technical issues related to the quantitative criteria for probabilistic risk analysis, establishment of containment performance criteria, design of additional water source for long-term corium cooling of core debris, protection against common mode failure of digital I and C system, criteria for safety-related operator action, quantitative reliability targets, classification of plant conditions and acceptance criteria and development of graded QA. These issues are parts of major technical issues resulted from the safety regulation R and D on the next generation reactor. Regulatory directions to be applied to the Korea Next Generation Reactors in this study are developed by analyzing the state-of-the-art of the development of local and foreign regulatory requirements, research trends, and the design features and safety goals of advanced reactors.

  8. Providing Value to New Health Technology: The Early Contribution of Entrepreneurs, Investors, and Regulatory Agencies

    Science.gov (United States)

    Lehoux, Pascale; Miller, Fiona A.; Daudelin, Geneviève; Denis, Jean-Louis

    2017-01-01

    Background: New technologies constitute an important cost-driver in healthcare, but the dynamics that lead to their emergence remains poorly understood from a health policy standpoint. The goal of this paper is to clarify how entrepreneurs, investors, and regulatory agencies influence the value of emerging health technologies. Methods: Our 5-year qualitative research program examined the processes through which new health technologies were envisioned, financed, developed and commercialized by entrepreneurial clinical teams operating in Quebec’s (Canada) publicly funded healthcare system. Results: Entrepreneurs have a direct influence over a new technology’s value proposition, but investors actively transform this value. Investors support a technology that can find a market, no matter its intrinsic value for clinical practice or healthcare systems. Regulatory agencies reinforce the "double" value of a new technology—as a health intervention and as an economic commodity—and provide economic worth to the venture that is bringing the technology to market. Conclusion: Policy-oriented initiatives such as early health technology assessment (HTA) and coverage with evidence may provide technology developers with useful input regarding the decisions they make at an early stage. But to foster technologies that bring more value to healthcare systems, policy-makers must actively support the consideration of health policy issues in innovation policy.

  9. Regulatory Risk Reduction for Advanced Reactor Technologies – FY2016 Status and Work Plan Summary

    Energy Technology Data Exchange (ETDEWEB)

    Moe, Wayne Leland [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    Millions of public and private sector dollars have been invested over recent decades to realize greater efficiency, reliability, and the inherent and passive safety offered by advanced nuclear reactor technologies. However, a major challenge in experiencing those benefits resides in the existing U.S. regulatory framework. This framework governs all commercial nuclear plant construction, operations, and safety issues and is highly large light water reactor (LWR) technology centric. The framework must be modernized to effectively deal with non-LWR advanced designs if those designs are to become part of the U.S energy supply. The U.S. Department of Energy’s (DOE) Advanced Reactor Technologies (ART) Regulatory Risk Reduction (RRR) initiative, managed by the Regulatory Affairs Department at the Idaho National Laboratory (INL), is establishing a capability that can systematically retire extraneous licensing risks associated with regulatory framework incompatibilities. This capability proposes to rely heavily on the perspectives of the affected regulated community (i.e., commercial advanced reactor designers/vendors and prospective owner/operators) yet remain tuned to assuring public safety and acceptability by regulators responsible for license issuance. The extent to which broad industry perspectives are being incorporated into the proposed framework makes this initiative unique and of potential benefit to all future domestic non-LWR applicants

  10. Legal and regulatory issues affecting the aquifer thermal energy storage concept

    Energy Technology Data Exchange (ETDEWEB)

    Hendrickson, P.L.

    1980-10-01

    A number of legal and regulatory issus that potentially can affect implementation of the Aquifer Thermal Energy Storage (ATES) concept are examined. This concept involves the storage of thermal energy in an underground aquifer until a later date when it can be effectively utilized. Either heat energy or chill can be stored. Potential end uses of the energy include district space heating and cooling, industrial process applications, and use in agriculture or aquaculture. Issues are examined in four categories: regulatory requirements, property rights, potential liability, and issues related to heat or chill delivery.

  11. Ethical Issues in Technology Education in Taiwan

    Science.gov (United States)

    Lin, Kuen-Yi

    2007-01-01

    A significant trend in technology education has shown internationally widespread acceptance with the increasing needs of developing students' technological literacy on both the elementary and secondary level from manual training to basic competency. Therefore, more and more countries have developed their national technology standards in order to…

  12. Policy issues inherent in advanced technology development

    Energy Technology Data Exchange (ETDEWEB)

    Baumann, P.D.

    1994-12-31

    In the development of advanced technologies, there are several forces which are involved in the success of the development of those technologies. In the overall development of new technologies, a sufficient number of these forces must be present and working in order to have a successful opportunity at developing, introducing and integrating into the marketplace a new technology. This paper discusses some of these forces and how they enter into the equation for success in advanced technology research, development, demonstration, commercialization and deployment. This paper limits itself to programs which are generally governmental funded, which in essence represent most of the technology development efforts that provide defense, energy and environmental technological products. Along with the identification of these forces are some suggestions as to how changes may be brought about to better ensure success in a long term to attempt to minimize time and financial losses.

  13. Regulatory issues of digital instrumentation and control system in Lungmen project

    Energy Technology Data Exchange (ETDEWEB)

    Chuang, C.F. [Nuclear Regulation Division, Atomic Energy Council, Taipei (China); Chou, H.P. [Department of Engineering and System Science National Tsing Hua University, (China)

    2004-07-01

    The Lungmen Nuclear Power Station (LNPS) is currently under construction in Taiwan, which consists of 2 advanced boiling water reactor (ABWR) units. The instrumentation and control (IC) systems of the LNPS are based on the state-of-the-art modernized fully integrated digital design. These IC systems possess many advantages and distinguished features comparing to traditional analog IC systems, they enjoy set-point stability, self-diagnostic and automatic testing ability, fault tolerance and avoidance, low power requirements, data handling and storage capability, as well as enhanced human-machine interfaces. This paper presents regulatory overviews, regulatory requirements, current major regulatory issues, as well as the areas of regulatory concerns and the lessons learned on the digital IC systems in the Lungmen Project.

  14. Japan's regulatory and safety issues regarding nuclear materials transport

    Energy Technology Data Exchange (ETDEWEB)

    Saito, T. [Nuclear and Industrial Safety Agency, Ministry of Economy, Trade and Industry, Government of Japan, Tokyo (Japan); Yamanaka, T. [Japan Nuclear Energy Safety Organization, Government of Japan, Tokyo (Japan)

    2004-07-01

    This paper focuses on the regulatory and safety issues on nuclear materials transport which the Government of Japan (GOJ) faces and needs to well handle. Background information about the status of nuclear power plants (NPP) and nuclear fuel cycle (NFC) facilities in Japan will promote a better understanding of what this paper addresses.

  15. Franchising Technology Education: Issues and Implications.

    Science.gov (United States)

    Daniel, Dan; Newcomer, Cynthia

    1993-01-01

    Describes educational technology franchises that sell services to students, either through schools or directly through retail centers, to educate them about and with technology. Topics addressed include the emphasis on personalized instruction; cooperative learning; curriculum; cost effectiveness; site-based management in public education; and…

  16. Trends and Research Issues in Educational Technology

    Science.gov (United States)

    Spector, J. Michael

    2013-01-01

    If one looks back at the last 50 years or so at educational technologies, one will notice several things. First, the pace of innovation has increased dramatically with many developments in the application of digital technologies to learning and instruction, following by a few years developments in the sciences and engineering disciplines that are…

  17. Telecare technologies and isolation: some ethical issues

    OpenAIRE

    Eccles A

    2015-01-01

    Andrew Eccles School of Social Work & Social Policy, University of Strathclyde, Glasgow, UK Abstract: Telecare technologies involve the remote monitoring of patients who have health, rehabilitation or social needs. These technologies, although deployed unevenly in developed countries, represent a shift in the ways in which care is practiced. Research on the consequences of this shift away from more traditional "hands-on" care has focused primarily on quantitative me...

  18. Remedial actions: A discussion of technological, regulatory and construction issues

    Energy Technology Data Exchange (ETDEWEB)

    Manrod, W.E.; Miller, R.A.; Barton, W.D. III; Pierce, T.J. [Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States). Engineering Div.

    1989-11-01

    The Oak Ridge Reservation consists of approximately 35,252 acres located in the Ridge and Valley Province of the Appalachian Mountains in Eastern Tennessee. Three Department of Energy facilities are located on the Reservation: the Y-12 Plant, the Oak Ridge Gaseous Diffusion Plant and the Oak Ridge National Laboratory. The plants have, over the years, disposed of low-level and mixed waste in various areas on the reservation principally with shallow land burial. A discussion is presented of some of the actions to remediate and close areas used for disposal of waste in the past. Current or planned activities for waste disposal and storage are also discussed. Closures completed to date have complied with Resource Conservation and Recovery Act Regulations. The new approach for disposal and storage has adopted ideas that have been successfully used by the French to dispose of low-level waste, as well as, improved on older shallow burial disposal techniques.

  19. Information technology research and development critical trends and issues

    CERN Document Server

    1985-01-01

    Information Technology Research and Development: Critical Trends and Issues is a report of the Office of Technology Assessment of the United States Government on the research and development in the area of information technology. The report discusses information technology research and development - its goals, nature, issues, and strategies; environment and its changes; the roles of the participants; and the health of its field. The book then goes on to four selected case studies in information technology: advanced computer architecture; fiber optic communications; software engineering; and ar

  20. Trends, Issues, and Gaps in Technology for Elementary Social Studies.

    Science.gov (United States)

    Nickell, Pat; Field, Sherry L.; Roach, Pamela S.

    2001-01-01

    Addresses the status of technology in elementary social studies. Reviews research on technology and elementary social studies, explores various examples of practice, discusses how preservice social studies methods textbooks treat the issue of using technology, and identifies beliefs held by elementary social studies teachers. (CMK)

  1. Ethical issues in modern biological technologies.

    Science.gov (United States)

    Bhargava, Pushpa M

    2003-10-01

    Today's biology-based technologies have emerged from a historical imperative and as an inevitable consequence of developments in modern biology beginning in the last half-century. They can be classified into almost 30 different areas, ranging from the use of gene therapy for human beings, enzyme engineering, stem cells and cloning, to marine biotechnology, bioinformatics, nanotechnology and biological warfare among many others. Many of them have major sociopolitico-economic, moral, ethical and legal implications. They include genetic engineering, gene therapy, tissue culture, stem cell work, the new DNA technologies, commercialization of traditional plant-based drug formulations, assisted reproduction techniques, cloning technologies, organ transplantation, bioinformatics, and biological weapons. Examples of the ethical implications of several of these items will be considered. They will be assessed with special reference to ethical implications in respect of assisted reproduction techniques, of worldwide importance today, particularly for a country such as India.

  2. Gender, Conjugalities and assisted reproductive technologies: regulatory aspects and practices in different scenarios

    Directory of Open Access Journals (Sweden)

    Luciane da Costa Moás

    2015-06-01

    Full Text Available The present article focuses on the construction of the reproductive practices in the access to assisted reproduction in which the conjugal sexuality, family dynamics and regulatory instances are intertwined. Considering the cultural and symbolic dimension inherent to the production of bodies, the identity processes in the contemporary scene pose challenges to the realization of the desire for children both under the heterosexual and homosexual conjugalities. Regulations and decision-making issues regarding the use of reproductive technologies are addressed, as well as the elements present in the marital dynamic involving the desire for a "natural" reproduction via assisted technologies. Prescriptive medical and legal parameters that do not match the experience of couples and individuals who turn to assisted reproductive technologies were found in this work.

  3. Module Technology: Current Practice and Issues (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Wohlgemuth, J.

    2010-10-05

    PV modules must provide mechanical support for the cells, protect the world from the voltages inside, protect the cells, diodes and interconnects from the weather outside, couple as much light as possible into the PV cells and minimize the temperature increase of the cells. The package must continue to serve these functions for at least 25 years as that is the typical module warranty period today. Furthermore the package must do all this for as low a cost as possible since the key to large scale PV growth is a reduction in cost while retaining excellent module reliability and durability. This paper will review current module construction practices for both crystalline silicon and thin film PV with emphasis on explaining why the present designs and materials have been selected. Possible long term issues with today's designs and materials will be discussed. Several proposed solutions to these issues will be presented, highlighting the research efforts that will be necessary in order to verify that they can cost effectively solve the identified issues.

  4. Man and His Technology: Problems and Issues.

    Science.gov (United States)

    Piel, E. J.; Truxal, John G.

    This book looks at a sampling of notable socio-technical problems within a rational context. It seeks to determine if problems exist with recent decisions in the application of technology; how threatening any problems may be; the source of problems; and examines alternatives available to the nation. The broad goal of this rational consideration is…

  5. Sanitary technology. Special issue; Sanitairtechniek. Themanummer

    Energy Technology Data Exchange (ETDEWEB)

    Lodder, H. [Deerns Raadgevende Ingenieurs, Rijswijk (Netherlands); De Veer, T. [PWN Waterleidingbedrijf Noord-Holland, Velserbroek (Netherlands); Korstanje, H.; De Gids, Ph. K. [LegioFreeWaterSystems, Wijk bij Duurstede (Netherlands); Lansbergen, A. [Itho, Schiedam (Netherlands); Scheffer, W.J.H. [UNETO-VNI, Zoetermeer (Netherlands); Van Wolferen, H. [TNO Milieu en Energie, Apeldoorn (Netherlands); Donker, H. [Kemper Nederland, Groenlo (Netherlands); Engelenburg, M. [ATECA, Den Haag (Netherlands); Wolters, J. [Tour en Andersson, Alphen aan den Rijn (Netherlands); Doldersum, R.H. [De Melker Sanitairtechniek, Veenendaal (Netherlands)

    2007-09-15

    In 11 articles attention is paid to several aspects of sanitary technology, in particular the prevention and control of legionella in heating systems and water supply installations. [Dutch] In 11 artikelen wordt aandacht besteed aan verschillende aspecten m.b.t. sanitaire techniek, in het bijzonder legionella preventie en beheer in verwarmingssystemen en leidingwaterinstallaties.

  6. Regulatory Technology Development Plan - Sodium Fast Reactor. Mechanistic Source Term - Trial Calculation. Work Plan

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David [Argonne National Lab. (ANL), Argonne, IL (United States); Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States); Jerden, James [Argonne National Lab. (ANL), Argonne, IL (United States); Brunett, Acacia J. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-02-01

    The overall objective of the SFR Regulatory Technology Development Plan (RTDP) effort is to identify and address potential impediments to the SFR regulatory licensing process. In FY14, an analysis by Argonne identified the development of an SFR-specific MST methodology as an existing licensing gap with high regulatory importance and a potentially long lead-time to closure. This work was followed by an initial examination of the current state-of-knowledge regarding SFR source term development (ANLART-3), which reported several potential gaps. Among these were the potential inadequacies of current computational tools to properly model and assess the transport and retention of radionuclides during a metal fuel pool-type SFR core damage incident. The objective of the current work is to determine the adequacy of existing computational tools, and the associated knowledge database, for the calculation of an SFR MST. To accomplish this task, a trial MST calculation will be performed using available computational tools to establish their limitations with regard to relevant radionuclide release/retention/transport phenomena. The application of existing modeling tools will provide a definitive test to assess their suitability for an SFR MST calculation, while also identifying potential gaps in the current knowledge base and providing insight into open issues regarding regulatory criteria/requirements. The findings of this analysis will assist in determining future research and development needs.

  7. Science and technology review, October 1998 issue

    Energy Technology Data Exchange (ETDEWEB)

    Smart, J

    1998-10-01

    A mobile radar system for inspecting bridges. Laser pulses to strengthen metal. A new kind of key that uses lasers. An imaging system that reveals the insides of teeth. A novel method to measure temperature. Computer software that boosts semiconductor production. And a detector to aid optics manufacturing efficiency. These inventions by Lawrence Livermore National Laboratory researchers and their industrial partners were recently honored by R&D Magazine as seven of the top 100 technological achievements of the past year.

  8. Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies.

    Science.gov (United States)

    Gelderman, Grant; Contreras, Lydia M

    2013-01-01

    Next generation sequencing (NGS) has revolutionized the way by which we engineer metabolism by radically altering the path to genome-wide inquiries. This is due to the fact that NGS approaches offer several powerful advantages over traditional methods that include the ability to fully sequence hundreds to thousands of genes in a single experiment and simultaneously detect homozygous and heterozygous deletions, alterations in gene copy number, insertions, translocations, and exome-wide substitutions that include "hot-spot mutations." This chapter describes the use of these technologies as a sequencing technique for transcriptome analysis and discovery of regulatory RNA elements in the context of three main platforms: Illumina HiSeq, 454 pyrosequencing, and SOLiD sequencing. Specifically, this chapter focuses on the use of Illumina HiSeq, since it is the most widely used platform for RNA discovery and transcriptome analysis. Regulatory RNAs have now been found in all branches of life. In bacteria, noncoding small RNAs (sRNAs) are involved in highly sophisticated regulatory circuits that include quorum sensing, carbon metabolism, stress responses, and virulence (Gorke and Vogel, Gene Dev 22:2914-2925, 2008; Gottesman, Trends Genet 21:399-404, 2005; Romby et al., Curr Opin Microbiol 9:229-236, 2006). Further characterization of the underlying regulation of gene expression remains poorly understood given that it is estimated that over 60% of all predicted genes remain hypothetical and the 5' and 3' untranslated regions are unknown for more than 90% of the genes (Siegel et al., Trends Parasitol 27:434-441, 2011). Importantly, manipulation of the posttranscriptional regulation that occurs at the level of RNA stability and export, trans-splicing, polyadenylation, protein translation, and protein stability via untranslated regions (Clayton, EMBO J 21:1881-1888, 2002; Haile and Papadopoulou, Curr Opin Microbiol 10:569-577, 2007) could be highly beneficial to metabolic

  9. Regulatory and ethical issues on the utilization of FFPE tissues in research.

    Science.gov (United States)

    With, Catherine M; Evers, David L; Mason, Jeffrey T

    2011-01-01

    Formalin-fixed, paraffin-embedded (FFPE) archival tissues and their associated diagnostic records represent an invaluable source of information on diseases where the patient outcomes are already known. Older archives contain many unique FFPE tissue specimens that would be impossible to replicate today due to changes in medical practice and technology. Unfortunately, there is no single regulatory or bioethical standard that covers research with FFPE tissue specimens. This makes it difficult for researchers to prepare protocols involving FFPE tissues and equally difficult for Institutional Review Boards to evaluate them. In this review, focused on US regulatory policy, the application of the Common Rule and the Privacy Rule of the Health Insurance Portability and Accountability Act to research involving FFPE tissue specimens will be discussed. It will be shown that the difficulty in applying regulatory and ethical standards to FFPE tissues results not from the tissues themselves, but from the personally identifiable health information associated with the tissue specimens.

  10. Thermal food processing: new technologies and quality issues

    National Research Council Canada - National Science Library

    Sun, Da-Wen

    2012-01-01

    .... The editor of Thermal Food Processing: New Technologies and Quality Issues presents a comprehensive reference through authors that assist in meeting this challenge by explaining the latest developments and analyzing the latest trends...

  11. Managing the Organizational Culture: A Technological Issue

    Directory of Open Access Journals (Sweden)

    Takhir U. Bazarov

    2011-01-01

    Full Text Available Organizational culture presents an interest for research and practice of social psychology. This article is intended to discuss the problem of managing the organizational structure on two levels that contain most topical problems: general methodological level and technological level. Organizational culture is a system with its distinct features that consists of units and sub-systems with their specific features. An organizational-culture system comprises several levels: leader's personality level (as well as the personality level in general, level of executive team (as well as of a small group in general, level of organization in general (level of a large group.

  12. How technology transfer issues are managed

    Energy Technology Data Exchange (ETDEWEB)

    Sink, C.H. [Dept. of Energy, Washington, DC (United States); Easley, K.R. [Waste Policy Inst. (United States)

    1991-12-31

    In 1989, Secretary of Energy James Watkins made a commitment to accelerate DOE compliance with all applicable laws and standards aimed at protecting human health and the environment. At a minimum, this pledge requires the remediation of the 1989 inventory of chemical, radioactive, and mixed wastes at DOE production sites by 2019. The 1989 Complex inventory consisted of more than 3,700 sites, encompassing more than 26,000 acres contaminated with radioactive, hazardous, and mixed wastes. In addition, over 500 surplus sites are awaiting decontamination and decommissioning (D and D), and approximately 5,000 peripheral properties have contaminated soils (e.g., uranium tailings). Moreover, these problems exist at both inactive sites, where the primary focus is on environmental restoration, and at active sites, where the major emphasis is on improved waste management techniques. Although some of DOE`s problems are considered unique due to radioactivity, most forms of contamination resident in the Complex are not; rather, contaminants such as waste chemicals (e.g., inorganics), organics (e.g., fuels and solvents), halogenated organics (e.g., PCBs) and heavy metals commonly result in conventional industrial processes. Although certain other forms of contamination are more unique to DOE operations (e.g., radioactive materials, explosives, and pyrophorics), they are not exclusive to DOE. As DOE develops innovative solutions to these and related waste problems, it is imperative that technology systems and lessons learned be transferred from DOE sites and its R and D laboratories to private industry to maximize the nation`s return on environmental management technology investments.

  13. Several Legal Issues Relating to Service Technological Results

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    How "the rights and interests in the intellectual property rights of the scientists and technicians should be protected and the entity achieving the service-related technological results should remunerate, under law, those achieving the service-related technological results and those making outstanding contribution to the transfer of the technological results" are important issues encountered in China in its efforts to improve its innovation capacity and build up a new nation. The current legal system in...

  14. Strategic issues in information technology international implications for decision makers

    CERN Document Server

    Schütte, Hellmut

    1988-01-01

    Strategic Issues in Information Technology: International Implications for Decision Makers presents the significant development of information technology in the output of components, computers, and communication equipment and systems. This book discusses the integration of information technology into factories and offices to increase productivity.Organized into six parts encompassing 12 chapters, this book begins with an overview of the advancement towards an automated interpretation communication system to achieve real international communication. This text then examines the main determining

  15. Special Issue on Nanotechnology, Optoelectronics and Photonics Technologies

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    International Conference on Nanotechnology, Optoelec- tronics and Photonics Technologies (NOPT) is an annual International Conference sponsored by Photonics and Microelectronics Society and Components, Packaging & Manufacturing Society of IACSIT (International Associa- tion of Computer Science and Information Technology), and sponsored by JEST (International), Journal of Electronic Science and Technology. The annual conference aims to provide a forum for researchers and experts in the relevant fields to share ideas, present current states of researches, and discuss both theoretical and application issues.

  16. Ethical and regulatory challenges in psychophysiology and neuroscience-based technology for determining behavior.

    Science.gov (United States)

    Shamoo, Adil E

    2010-01-01

    In the past three decades, there has been an explosion in research to understand the mechanisms of brain function. Recent advances in psychophysiology and neuroscience, while still limited, have sparked great interest in developing technologies that could peer into the brain and be used to identify or indicate certain behaviors. The polygraph (lie detector) represents an old technology used for discerning clues to the human brain; functional magnetic resonance imaging (fMRI) represents one of the newest efforts. The use of these technologies in intelligence and counterintelligence in the field without validation represents a major concern about its usefulness. Both research on this new technology and subsequent use on public raise ethical challenges. This article will address the overall ethical issues associated with these new technologies. The report identifies the ethical and cultural challenges in conducting research on these new tools, explores the possibility of using current U.S. regulatory requirements regarding drugs and devices as a model for regulating these new technologies, and suggests approaches for the future.

  17. Women Technology Leaders: Gender Issues in Higher Education Information Technology

    Science.gov (United States)

    Drury, Marilyn

    2011-01-01

    Women working in higher education information technology (IT) organizations and those seeking leadership positions in these organizations face a double challenge in overcoming the traditionally male-dominated environments of higher education and IT. Three women higher education chief information officers (CIOs) provided their perspectives,…

  18. VLSI Technology: Impact and Promise. Identifying Emerging Issues and Trends in Technology for Special Education.

    Science.gov (United States)

    Bayoumi, Magdy

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the implications of very large scale integrated (VLSI) technology. The first section reviews the development of educational technology, particularly microelectronics technology, from the 1950s to the present. The implications…

  19. Overcoming language barriers in the informed consent process: regulatory and compliance issues with the use of the "short form".

    Science.gov (United States)

    Lad, Pramod M; Dahl, Rebecca

    2014-01-01

    Language barriers in the informed consent process can be a significant impediment when recruiting non-English speaking subjects into clinical research studies. Regulatory guidelines indicate that the short form procedure be utilized in such circumstances. In this paper, we examine some of the ambiguities in the regulatory framework, the resulting need for institutional policy guidelines, and compliance issues with the short form process.

  20. 18 CFR 2.1a - Public suggestions, comments, proposals on substantial prospective regulatory issues and problems.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Public suggestions, comments, proposals on substantial prospective regulatory issues and problems. 2.1a Section 2.1a Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY...

  1. Mobile technology and healthcare: the adoption issues and systemic problems.

    Science.gov (United States)

    Standing, Susan; Standing, Craig

    2008-01-01

    Although the benefits that are associated with mobile technology have been recognised as offering great potential in the healthcare sector, its widespread adoption has been lagging. We propose that fundamental systemic issues are likely to be the main barriers to adoption. We explain that the fragmented nature of the conservative healthcare system, the contradictory incentives and improper outcome measures conspire to make the innovative adoption of mobile technology problematic. Researchers can only gain a limited understanding of a technology's potential success by using technology adoption frameworks and need to supplement this with a 'systems' perspective that takes a more strategic view.

  2. The triad of success in personalised medicine: pharmacogenomics, biotechnology and regulatory issues from a Central European perspective.

    Science.gov (United States)

    Mesko, Bertalan; Zahuczky, Gabor; Nagy, Laszlo

    2012-09-15

    The population of the world has recently passed the 7 billion milestone and as the cost of human genome sequencing is rapidly declining, sequence data of billions of people should be accessible much sooner than anyone would have predicted 10 years ago. This will form the basis of personalised medicine. However it is still not clear, even in principle, whether these data, combined with data of the expression of one's genome in various cells and tissues relevant to different diseases, could be used effectively in clinical medicine and healthcare, or in predicting responses to different therapies. Therefore this is an important issue which needs to be addressed before more resources are wasted on less than informative studies and surveys simply because technologies exist. As a typical example, we have selected and summarise here key studies from the biomedical literature that focus on gene expression profiling of the response to biologic therapies in peripheral blood and biopsy samples in autoimmune diseases such as rheumatoid arthritis, spondylarthropathy, inflammatory bowel diseases and psoriasis. We also present the state of the biotechnology market from a European perspective, discuss how spin-offs leverage the power of genomic technologies and describe how they might contribute to personalised medicine. As ethical, legal and social issues are essential in the area of genomics, we analysed these aspects and present here the European situation with a special focus on Hungary. We propose that the synergy of these three issues: pharmacogenomics, biotechnology and regulatory issues should be considered a triad necessary to succeed in personalised medicine. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. California renewable energy policy and implementation issues: An overview of recent regulatory and legislative action

    Energy Technology Data Exchange (ETDEWEB)

    Wiser, R.; Pickle, S.; Goldman, C.

    1996-09-01

    This paper has three primary goals: (1) to provide a brief account of recent events in California renewables policy; (2) to outline the California State Legislature`s ultimate decision on renewable energy policy; and (3) to aid other states in their efforts with renewables policy by summarizing some of the key implementation issues and political conflicts that may occur when crafting some of the potential threats and opportunities that electricity restructuring presents to the development of renewable energy. We then outline the renewables policy debate in California since the California Public Utility Commission`s ``Blue Book``, including both regulatory and legislative developments. We also provide some insight into the minimum renewables purchase requirement (MRPR) versus surcharge-based renewables policy debate in California. Finally, we identify and discuss key renewables policy implementation issues that have driven the dialogue and recent decisions in California`s renewables policy.

  4. Effective surveillance for homeland security balancing technology and social issues

    CERN Document Server

    Flammini, Francesco; Franceschetti, Giorgio

    2013-01-01

    Effective Surveillance for Homeland Security: Balancing Technology and Social Issues provides a comprehensive survey of state-of-the-art methods and tools for the surveillance and protection of citizens and critical infrastructures against natural and deliberate threats. Focusing on current technological challenges involving multi-disciplinary problem analysis and systems engineering approaches, it provides an overview of the most relevant aspects of surveillance systems in the framework of homeland security. Addressing both advanced surveillance technologies and the related socio-ethical issues, the book consists of 21 chapters written by international experts from the various sectors of homeland security. Part I, Surveillance and Society, focuses on the societal dimension of surveillance-stressing the importance of societal acceptability as a precondition to any surveillance system. Part II, Physical and Cyber Surveillance, presents advanced technologies for surveillance. It considers developing technologie...

  5. Health information technology: medical record documentation issues in the electronic era.

    Science.gov (United States)

    Dacey, Bill; Bholat, Michelle Anne

    2012-12-01

    This article outlines the regulatory movement propelling physicians into the electronic health record environment and the subsequent emergence of quality issues in the medical record. There are benefits and downside risks for implementing electronic health records as part of the desire of a practice or institution to build patient-centered medical homes. The intersection of how a practice or institution collects and reports quality metrics using health information technology and subsequently submits claims for services rendered has created unforeseen challenges for which leadership must be aware and address proactively.

  6. Teaching Undergraduate Mathematics Using CAS Technology: Issues and Prospects

    Science.gov (United States)

    Tobin, Patrick C.; Weiss, Vida

    2016-01-01

    The use of handheld CAS technology in undergraduate mathematics courses in Australia is paradoxically shrinking under sustained disapproval or disdain from the professional mathematics community. Mathematics education specialists argue with their mathematics colleagues over a range of issues in course development and this use of CAS or even…

  7. REVIEW: Trends And Issues In Instructional Design And Technology

    OpenAIRE

    AKBULUT, Reviewed By Yavuz

    2015-01-01

    “Trends and Issues in Instructional Design and Technology” is a reader friendly reference source on instructional design and technology (IDT) helping both professionals in the field and novice practitioners trying to get used to the trends and concepts of the field.

  8. Regulatory framework and examples of ground-source heating/cooling technology in the Winnipeg area

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, R. [Manitoba Conservation, Winnipeg, MB (Canada)

    2003-07-01

    Winnipeg, Manitoba lies over a highly transmissive Carbonate Aquifer of Ordovician age, which provides a suitable environment for groundwater supply and return wells. Many licensed ground-source heating cooling (GSHC) systems have been installed in and around the Winnipeg urban area over the last several decades. A water rights licence, issued by the Provincial Department of Conservation, is required for all groundwater supply and return wells. This licence comes with certain rights and responsibilities. This paper describes the regulatory framework which governs the licensing process. The author emphasized that the future use and success of the technology depends, in large part, on the development of a critical mass of experienced contractors, hydrogeologists and consulting engineers. 2 refs.

  9. Learning the Hard Way? Issues in the Adoption of New Technology in Small Technology Oriented Firms

    Science.gov (United States)

    Chibelushi, Caroline

    2008-01-01

    Purpose: The purpose of this paper is to explore, through a survey and two short case studies, the issues smaller firms face with the adoption of new technologies. Design/methodology/approach: A survey of the pressures to adopt new technologies and the existence of specialist technology skills was conducted of small ICT oriented firms in the West…

  10. Cloud Computing : Goals, Issues, SOA, Integrated Technologies and Future -scope

    Directory of Open Access Journals (Sweden)

    V. Madhu Viswanatham

    2016-10-01

    Full Text Available The expansion of networking infrastructure has provided a novel way to store and access resources in a reliable, convenient and affordable means of technology called the Cloud. The cloud has become so popular and established its dominance in many recent world innovations and has highly influenced the trend of the Business process Management with the advantage of shared resources. The ability to remain disaster tolerant, on-demand scalability, flexible deployment and cost effectiveness has made the future world technologies like Internet of Things, to determine the cloud as their data and processing center. However, along with the implementation of cloud based technologies, we must also address the issues involved in its realization. This paper is a review on the advancements, scopes and issues involved in realizing a secured cloud powered environments.

  11. Computer technology in education and issues of power and equity

    Directory of Open Access Journals (Sweden)

    Alper Kesten

    2010-05-01

    Full Text Available This study aims to use ‘techniques of power’ classified (based on Foucault’s work by Gore in order to illustrate power relations between supporters (or non-supporters of computer technology and teachers. For this purpose, six out of eight techniques of power (surveillance, normalization, exclusion, classification, distribution and regulation is used in formulating thoughts about computer technology and issues of power and equity. In this study, these techniques of power were discussed more detailed both to exemplify how supporters (or non-supporters of computer technology exercise power over teachers (preservice or inservice by using of major techniques of power and to show how they are related to the issue of equity.

  12. Print Me an Organ? Ethical and Regulatory Issues Emerging from 3D Bioprinting in Medicine.

    Science.gov (United States)

    Gilbert, Frederic; O'Connell, Cathal D; Mladenovska, Tajanka; Dodds, Susan

    2017-02-09

    Recent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then it focuses on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article (1) considers whether there is a limit as to what should be bioprinted in medicine; (2) examines key risks of significant harm associated with testing 3D bioprinting for humans; (3) investigates the clinical trial paradigm used to test 3D bioprinting; (4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability; (5) explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatments.

  13. Governing Nanomedicine: lessons from within, and for, the EU Medical Technology Regulatory Framework : Guest Editors Introduction

    NARCIS (Netherlands)

    Dorbeck-Jung, Bärbel; Bowman, Diana M.; Calster, van Geert

    2011-01-01

    Rapidly emerging technologies, such as nanotechnologies, are posing significant challenges to regulatory governance due to the uncertainties of development trajectories, product properties, and potential risk problems (Davies 2009). While nanotechnology-based products and processes fall within the s

  14. Energy sector in transition - technologies and regulatory policies in flux

    DEFF Research Database (Denmark)

    Jørgensen, Ulrik

    2005-01-01

    Liberalising the energy sector has been followed by a number of new regulatory measures that are argued to maintain a process towards a sustainable energy sector. The article argues based on empirical material from Denmark and other European countries that the EU regulations and especially the si...

  15. Environmental Decision Making and Information Technology: Issues Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Barg, S.; Fletcher, T.; Mechling, J.; Tonn, B.; Turner, R.

    1999-05-01

    This report presents a summary of the Information Technology and Environmental Decision Making Workshop that was held at Harvard University, October 1-3, 1998. Over sixty participants from across the US took part in discussions that focused on the current practice of using information technology to support environmental decision making and on future considerations of information technology development, information policies, and data quality issues in this area. Current practice is focusing on geographic information systems and visualization tools, Internet applications, and data warehousing. In addition, numerous organizations are developing environmental enterprise systems to integrate environmental information resources. Plaguing these efforts are issues of data quality (and public trust), system design, and organizational change. In the future, much effort needs to focus on building community-based environmental decision-making systems and processes, which will be a challenge given that exactly what needs to be developed is largely unknown and that environmental decision making in this arena has been characterized by a high level of conflict. Experimentation and evaluation are needed to contribute to efficient and effective learning about how best to use information technology to improve environmental decision making.

  16. History of artificial cold, scientific, technological and cultural issues

    CERN Document Server

    2014-01-01

    The history of artificial cold has been a rather intriguing interdisciplinary subject (physics, chemistry, technology, sociology, economics, anthropology, consumer studies) which despite some excellent monographs and research papers, has not been systematically exploited. It is a subject with all kinds of scientific, technological as well as cultural dimensions. For example, the common home refrigerator has brought about unimaginably deep changes to our everyday lives changing drastically eating habits and shopping mentalities. From the end of the 19th century to the beginning of the 21st, issues related to the production and exploitation of artificial cold have never stopped to provide us with an incredibly interesting set of phenomena, novel theoretical explanations, amazing possibilities concerning technological applications and all encompassing cultural repercussions. The discovery of the unexpected and “bizarre” phenomena of superconductivity and superfluidity, the necessity to incorporate macroscopi...

  17. Package leaflets of the most consumed medicines in Portugal: safety and regulatory compliance issues. A descriptive study

    Directory of Open Access Journals (Sweden)

    Carla Pires

    Full Text Available CONTEXT AND OBJECTIVES: Package leaflets are necessary for safe use of medicines. The aims of the present study were: 1 to assess the compliance between the content of the package leaflets and the specifications of the pharmaceutical regulations; and 2 to identify potential safety issues for patients. DESIGN AND SETTING: Qualitative descriptive study, involving all the package leaflets of branded medicines from the three most consumed therapeutic groups in Portugal, analyzed in the Department of Pharmacoepidemiology, School of Pharmacy, University of Lisbon. METHODS: A checklist validated through an expert consensus process was used to gather the data. The content of each package leaflet in the sample was classified as compliant or non-compliant with compulsory regulatory issues (i.e. stated dosage and descriptions of adverse reactions and optional regulatory issues (i.e. adverse reaction frequency, symptoms and procedures in cases of overdose. RESULTS: A total of 651 package leaflets were identified. Overall, the package leaflets were found to be compliant with the compulsory regulatory issues. However, the optional regulatory issues were only addressed in around half of the sample of package leaflets, which made it possible to identify some situations of potentially compromised drug safety. CONCLUSION: Ideally, the methodologies for package leaflet approval should be reviewed and optimized as a way of ensuring the inclusion of the minimum essential information for safe use of medicines.

  18. Some ethical issues in technology transfer and applications

    Science.gov (United States)

    Shine, Kenneth I.

    1995-10-01

    Health care systems all around the world are struggling to provide care in an era of limited resources. In an article entitled, 'Straight Talk About Rationing,' Arthur Kaplan reviews the work of the Swedish Commission designed to prioritize health care for that country. The commission identified three core principles that they felt should underlie decisions about priorities for health care. Those principles were (1) all human beings are equally valuable; (2) society must pay special attention to the needs of the weakest and most vulnerable; and (3) all other things being equal, cost efficiency in gaining the greatest return for the amount of money spent must prevail. These are three extremely useful principles which can be helpful to us as we consider many of the issues confronted in this country about the allocation of resources for health. I would like to consider three major issues. The first issue is the current evolving nature of health care and the ethical dilemmas that exist in the present system. In balancing increased access to care with decreasing cost, particularly in managed care, all of us are concerned about ethical issues. I would like to emphasize that the current system -- the system that we have lived with and is changing -- has inherent in it a series of ethical dilemmas. Secondly, I would like to consider issues related to productivity and its measurement in relation to technology. This relates to the third item in the Swedish Commission, which is the principle that we ought to spend money in the most cost-efficient way. Finally, I would like to discuss the dilemma of decision making about health and how that impacts upon the ethics of health care in the application of technology.

  19. Review report: safety and reliability issues on digital instrumentation and control systems in nuclear power plants and United States Nuclear Regulatory Commission`s dispositions

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Norio; Suzudo, Tomoaki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-09-01

    Recently, digital instrumentation and control (I and C) systems have been applied to nuclear power plants (NPPs) in various countries. Introduction of digital I and C systems, however, raises special issues on design, implementation, safety and licensing. Since FY 1997, the Japan Atomic Energy Research Institute (JAERI) has been carrying out a project, Study on Reliability of Digital I and C Systems, which includes extensive reviews of design approaches, technical standards, regulatory processes, especially, in the United States. This report summarizes the results from the study of National Research Council (NRC) and the U.S. Nuclear Regulatory Commission`s (USNRC`s) responses to the recommendations made by the NRC`s study. That study identified six technical key issues (system aspects of digital I and C technology, software quality assurance, common-mode software failure potential, safety and reliability assessment methods, human factors and man-machine interface, dedication of commercial off-the-shelf hardware and software) and two strategic key issues (case-by-case licensing process, adequacy of technical infrastructure) that arise from the introduction of digital I and C technology and then, made recommendations to the USNRC for coping with digital I and C applications. The USNRC responded to each recommendation and showed their own dispositions in which the USNRC agreed with most of the recommendations. In Japan, it is expected that introduction of digital I and C technology is inevitable in NPPs because the vendors are gradually discontinuing support and stocking of analog components. To cope with such situations, there is a need to develop and update the standards and guidelines applicable to digital I and C technology. The key issues and the USNRC`s dispositions provided in this report is believed to be useful for developing and updating them. (J.P.N.)

  20. Issues of social policy and ethics in gene technology.

    Science.gov (United States)

    Sade, R M

    1994-09-01

    Technical developments in the last ten years have made possible mapping and sequencing of the entire human genome, along with the possibility of treating genetic disorders by manipulating DNA. A variety of issues regarding potential uses and abuses of these technologies have become apparent. They relate to both genetic screening and gene therapy. Problems facing individuals and their families mostly revolve around rights of self-determination and of confidentiality. Health care professionals will need to design optimal systems to provide genetic counseling and to protect confidentiality of DNA data bases. Society and social institutions will need to develop policies and laws that protect the privacy of individuals whose DNA is stored in data banks. Patenting of the results of gene research remains controversial internationally. Moreover, there is concern in many quarters about society's potential abuse of gene technology for eugenic purposes. Gene therapy is now a reality. There is little disagreement on the use of gene therapy to treat genetic diseases in individuals by somatic cell therapy. There is much controversy, however, over the use of germ-line cell therapy. Gene technology has contributed to the growth among a small group of influential people of the Post-Modern Movement, which is strongly antiscience and antitechnology. This movement may pose a long-term threat to future technological advances and should not be ignored. There is much outside of the laboratory that scientists, particularly molecular biologists, can do to assure a secure place for science and technology in our culture.

  1. 77 FR 40817 - Low-Level Radioactive Waste Regulatory Management Issues

    Science.gov (United States)

    2012-07-11

    ...; ] NUCLEAR REGULATORY COMMISSION 10 CFR Part 61 RIN-3150-AI92 Low-Level Radioactive Waste Regulatory... associated with specifying a regulatory time of compliance for a low-level radioactive waste disposal... disposal of radioactive waste. DATES: The public meeting will be held on July 19, 2012, in Rockville...

  2. Emerging Issues and Opportunities in Health Information Technology.

    Science.gov (United States)

    Nardi, Elizabeth A; Lentz, Lisa Korin; Winckworth-Prejsnar, Katherine; Abernethy, Amy P; Carlson, Robert W

    2016-10-01

    When used effectively, health information technology (HIT) can transform clinical care and contribute to new research discoveries. Despite advances in HIT and increased electronic health record adoption, many challenges to optimal use, interoperability, and data sharing exist. Data standardization across systems is limited, and scanned medical note documents result in unstructured data that make reporting on quality measures for reimbursement burdensome. Different policies and initiatives, including the Health Information Technology for Economic and Clinical Health Act, the Medicare Access and CHIP Reauthorization Act, and the National Cancer Moonshot initiative, among others, all recognize the impact that HIT can have on cancer care. Given the growing role HIT plays in health care, it is vital to have effective and efficient HIT systems that can exchange information, collect credible data that is analyzable at the point of care, and improves the patient-provider relationship. In June 2016, NCCN hosted the Emerging Issues and Opportunities in Health Information Technology Policy Summit. The summit addressed challenges, issues, and opportunities in HIT as they relate to cancer care. Keynote presentations and panelists discussed moving beyond Meaningful Use, HIT readiness to support and report on quality care, the role of HIT in precision medicine, the role of HIT in the National Cancer Moonshot initiative, and leveraging HIT to improve quality of clinical care.

  3. Technological issues and experimental design of gene association studies.

    Science.gov (United States)

    Distefano, Johanna K; Taverna, Darin M

    2011-01-01

    Genome-wide association studies (GWAS), in which thousands of single-nucleotide polymorphisms (SNPs) spanning the genome are genotyped in individuals who are phenotypically well characterized, -currently represent the most popular strategy for identifying gene regions associated with common -diseases and related quantitative traits. Improvements in technology and throughput capability, development of powerful statistical tools, and more widespread acceptance of pooling-based genotyping approaches have led to greater utilization of GWAS in human genetics research. However, important considerations for optimal experimental design, including selection of the most appropriate genotyping platform, can enhance the utility of the approach even further. This chapter reviews experimental and technological issues that may affect the success of GWAS findings and proposes strategies for developing the most comprehensive, logical, and cost-effective approaches for genotyping given the population of interest.

  4. Obligations, precautions and pending issues in regulatory development for radiopharmaceuticals in Brazil

    Directory of Open Access Journals (Sweden)

    Maryelle Moreira Lima Gamboa

    2014-04-01

    Full Text Available Radiopharmaceuticals are compounds that have a radionuclide and may be gamma-radiation emitter (γ or positrons emitter (β+, linked to a molecule with specific diagnostic and therapeutic purposes. The progress in the use of radiopharmaceuticals has culminated to a sector in common with other types of drugs: regulation and surveillance. From 2006 on, production, marketing and use of these drugs were open to the Brazilian market granting much more freedom due to the Constitutional Amendment 49, resulting from the previous Constitutional Amendment 199/03 which removes the Union monopoly for this kind of manipulation and granted this production to other nuclear medicine. From this date on, the amount of this type of sold product have been greatly increased, and the nucleus of surveillance and regulation in Brazil have also advanced in the legislative processes, creating documents that are now more focused on radiopharmaceuticals in the national territory (Resolutions No. 63 and No. 64. In international overview, there is too much to be done in regulatory terms in Brazil, such as adding mainly issues of drugs surveillance to pharmacovigilance practice in radiopharmaceuticals drugs.

  5. The role of quality of life in functional gastrointestinal disorders: regulatory issues.

    Science.gov (United States)

    Bergmann, J F; Chassany, O

    1998-01-01

    Generic questionnaire such as SF36 and functional gastrointestinal disorder (FGD)-specific questionnaires (i.e. IBSQOL or FGDQL) are now available for the evaluation of new drugs for the treatment of irritable bowel syndrome or functional dyspepsia. For regulatory issues it is necessary to describe in detail the scale of the QOL questionnaire, its psychometric properties and reason for its choice, as well as validation studies, populations concerned, means of administration and methods for analysis. Preselection of few dimensions of the QOL questionnaire, if necessary, has to be explained. QOL results have to be compared with symptom scores. Trials have to be double-blind placebo- controlled studies with a sample size calculation taking account of the high placebo-response. No official guidelines are available in FGD and more validation studies are needed to help in the choice of the specific QOL questionnaire, in the metrologic analysis and in the interpretation of QOL changes during FGD treatment. Then QOL questionnaires could become a primary end point in clinical trials if efficient drugs for FGD treatment are developed.

  6. Obligations, precautions and pending issues in regulatory development for radiopharmaceuticals in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Gamboa, Maryelle Moreira Lima; Roesch, Heveline Rayane Moura; Lemos, Vanessa Pinheiro Amaral, E-mail: maryellelg@hotmail.com [PPG BioSaude, Universidade Luterana do Brasil, Canoas, RS (Brazil); Rocha, Bruna Oliveira [Faculty of Biology, Universidade Luterana do Brasil, Canoas, RS (Brazil); Santos-Oliveira, Ralph [Institute of Radiopharmacy Research, Universidade Estadual da Zona Oeste, Rio de Janeiro, RJ (Brazil)

    2014-04-15

    Radiopharmaceuticals are compounds that have a radionuclide and may be gamma-radiation emitter (γ) or positrons emitter (β+), linked to a molecule with specific diagnostic and therapeutic purposes. The progress in the use of radiopharmaceuticals has culminated to a sector in common with other types of drugs: regulation and surveillance. >From 2006 on, production, marketing and use of these drugs were open to the Brazilian market granting much more freedom due to the Constitutional Amendment 49, resulting from the previous Constitutional Amendment 199/03 which removes the Union monopoly for this kind of manipulation and granted this production to other nuclear medicine. From this date on, the amount of this type of sold product have been greatly increased, and the nucleus of surveillance and regulation in Brazil have also advanced in the legislative processes, creating documents that are now more focused on radiopharmaceuticals in the national territory (Resolutions No. 63 and No. 64). In international overview, there is too much to be done in regulatory terms in Brazil, such as adding mainly issues of drugs surveillance to pharmacovigilance practice in radiopharmaceuticals drugs. (author)

  7. Brand names of Portuguese medication: understanding the importance of their linguistic structure and regulatory issues

    Directory of Open Access Journals (Sweden)

    Carla Pires

    2015-08-01

    Full Text Available AbstractAmong other regulatory requirements, medicine brands should be composed of single names without abbreviations to prevent errors in prescription of medication. The purposes of the study were to investigate the compliance of a sam ple of Portuguese medicine brand names with Portuguese pharmaceutical regulations. This includes identifying their basic linguistic characteristics and comparing these features and their frequency of occurrence with benchmark values of the colloquial or informal language. A sample of 474 brand names was selected. Names were analyzed using manual (visual analyses and computer methods (FreP - Frequency Patterns of Phonological Objects in Portuguese and MS word. A significant number of names (61.3% failed to comply with the Portuguese phonologic system (related to the sound of words and/or the spelling system (related to the written form of words contained more than one word, comprised a high proportion of infrequent syllable types or stress patterns and included abbreviations. The results suggest that some of the brand names of Portuguese medication should be reevaluated, and that regulation on this issue should be enforced and updated, taking into consideration specific linguistic and spelling codes.

  8. Brand names of Portuguese medication: understanding the importance of their linguistic structure and regulatory issues.

    Science.gov (United States)

    Pires, Carla; Vigário, Marina; Cavaco, Afonso

    2015-08-01

    Among other regulatory requirements, medicine brands should be composed of single names without abbreviations to prevent errors in prescription of medication. The purposes of the study were to investigate the compliance of a sam ple of Portuguese medicine brand names with Portuguese pharmaceutical regulations. This includes identifying their basic linguistic characteristics and comparing these features and their frequency of occurrence with benchmark values of the colloquial or informal language. A sample of 474 brand names was selected. Names were analyzed using manual (visual analyses) and computer methods (FreP - Frequency Patterns of Phonological Objects in Portuguese and MS word). A significant number of names (61.3%) failed to comply with the Portuguese phonologic system (related to the sound of words) and/or the spelling system (related to the written form of words) contained more than one word, comprised a high proportion of infrequent syllable types or stress patterns and included abbreviations. The results suggest that some of the brand names of Portuguese medication should be reevaluated, and that regulation on this issue should be enforced and updated, taking into consideration specific linguistic and spelling codes.

  9. Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective.

    Science.gov (United States)

    Ono, Masahiro; Tanaka, Reiko J

    2016-01-01

    Thymus-derived regulatory T cells (Tregs) are considered to be a distinct T-cell lineage that is genetically programmed and specialised for immunosuppression. This perspective is based on the key evidence that CD25(+) Tregs emigrate to neonatal spleen a few days later than other T cells and that thymectomy of 3-day-old mice depletes Tregs only, causing autoimmune diseases. Although widely believed, the evidence has never been reproduced as originally reported, and some studies indicate that Tregs exist in neonates. Thus we examine the consequences of the controversial evidence, revisit the fundamental issues of Tregs and thereby reveal the overlooked relationship of T-cell activation and Foxp3-mediated control of the T-cell system. Here we provide a new model of Tregs and Foxp3, a feedback control perspective, which views Tregs as a component of the system that controls T-cell activation, rather than as a distinct genetically programmed lineage. This perspective provides new insights into the roles of self-reactivity, T cell-antigen-presenting cell interaction and T-cell activation in Foxp3-mediated immune regulation.

  10. Empowering Learners for Lifelong Competence Development: Pedagogical, Organizational and Technological Issues

    NARCIS (Netherlands)

    Sligte, Henk; Koper, Rob

    2008-01-01

    Sligte, H., & Koper, R. (Eds.) (2008). Empowering Learners for Lifelong Competence Development: Pedagogical, Organizational and Technological Issues. International Journal Emerging Technologies in Learning, 3, 4-6.

  11. Issues surrounding the health economic evaluation of genomic technologies

    Science.gov (United States)

    Buchanan, James; Wordsworth, Sarah; Schuh, Anna

    2014-01-01

    Aim Genomic interventions could enable improved disease stratification and individually tailored therapies. However, they have had a limited impact on clinical practice to date due to a lack of evidence, particularly economic evidence. This is partly because health economists are yet to reach consensus on whether existing methods are sufficient to evaluate genomic technologies. As different approaches may produce conflicting adoption decisions, clarification is urgently required. This article summarizes the methodological issues associated with conducting economic evaluations of genomic interventions. Materials & methods A structured literature review was conducted to identify references that considered the methodological challenges faced when conducting economic evaluations of genomic interventions. Results Methodological challenges related to the analytical approach included the choice of comparator, perspective and timeframe. Challenges in costing centered around the need to collect a broad range of costs, frequently, in a data-limited environment. Measuring outcomes is problematic as standard measures have limited applicability, however, alternative metrics (e.g., personal utility) are underdeveloped and alternative approaches (e.g., cost–benefit analysis) underused. Effectiveness data quality is weak and challenging to incorporate into standard economic analyses, while little is known about patient and clinician behavior in this context. Comprehensive value of information analyses are likely to be helpful. Conclusion Economic evaluations of genomic technologies present a particular challenge for health economists. New methods may be required to resolve these issues, but the evidence to justify alternative approaches is yet to be produced. This should be the focus of future work in this field. PMID:24236483

  12. Critical Issues Forum: A multidisciplinary educational program integrating computer technology

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, R.J.; Robertson, B.; Jacobs, D. [Los Alamos National Lab., NM (United States)

    1998-09-01

    The Critical Issues Forum (CIF) funded by the US Department of Energy is a collaborative effort between the Science Education Team of Los Alamos National Laboratory (LANL) and New Mexico high schools to improve science education throughout the state of New Mexico as well as nationally. By creating an education relationship between the LANL with its unique scientific resources and New Mexico high schools, students and teachers participate in programs that increase not only their science content knowledge but also their critical thinking and problem-solving skills. The CIF program focuses on current, globally oriented topics crucial to the security of not only the US but to that of all nations. The CIF is an academic-year program that involves both teachers and students in the process of seeking solutions for real world concerns. Built around issues tied to LANL`s mission, participating students and teachers are asked to critically investigate and examine the interactions among the political, social, economic, and scientific domains while considering diversity issues that include geopolitical entities and cultural and ethnic groupings. Participants are expected to collaborate through telecommunications during the research phase and participate in a culminating multimedia activity, where they produce and deliver recommendations for the current issues being studied. The CIF was evaluated and found to be an effective approach for teacher professional training, especially in the development of skills for critical thinking and questioning. The CIF contributed to students` ability to integrate diverse disciplinary content about science-related topics and supported teachers in facilitating the understanding of their students using the CIF approach. Networking technology in CIF has been used as an information repository, resource delivery mechanism, and communication medium.

  13. Engineering Issue: Technology Alternatives for the Remediation of PCB Contaminated Soils and Sediments

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) Engineering Issue papers are a series of documents that summarize the available information on specific contaminates, selected treatment and site remediation technologies, and related issues. This Engineering Issue paper is intended...

  14. Regulatory Analysis for the resolution of Generic Issue 142: Leakage through electrical isolators in instrumentation circuits

    Energy Technology Data Exchange (ETDEWEB)

    Rourk, C.J.

    1993-09-01

    Generic Issue (GI) 142 deals with staff concerns about the design of isolation devices used to ensure separation between Class 1E and non-Class 1E electrical control and instrumentation circuits. This issue was initiated in June 1987. Staff reviews of the implementation of the Safety Parameter Display System (SPDS) requirement indicated that some isolation devices used to provide an interface between the non-Class 1E SPDS and the Class 1E safety systems would allow signal leakage if electrically challenged. It was unknown if the amount of leakage posed a hazard to safe operation of the Class 1E system. A review of failure records does not reveal any incidents of system damage caused by isolation device challenge. Furthermore, a review of existing PRA data indicates that the safety significance of ID challenge is low, at the expected challenge event frequency. However, based upon the potential design variations in future control systems resulting from application of computer technology, additional design and qualification test requirements for future plants are recommended.

  15. National Security and Information Technology: The New Regulatory Option?

    Science.gov (United States)

    Irwin, Manley R.

    1987-01-01

    Summarizes recent developments in information technology research and development, telecommunication services, telephone manufacturing, telecommunication networks, information processing, and U.S. import/export policy. It is concluded that government regulation as a policy strategy depends on how one defines national security. (Author/CLB)

  16. Workshop on technology issues of superconducting Maglev transportation systems

    Energy Technology Data Exchange (ETDEWEB)

    Wegrzyn, J.E. (Brookhaven National Lab., Upton, NY (United States)); Shaw, D.T. (New York State Inst. of Superconductivity, Buffalo, NY (United States))

    1991-09-27

    There exists a critical need in the United States to improve its ground transportation system. One suggested system that offers many advantages over the current transportation infrastructure is Maglev. Maglev represents the latest evolution in very high and speed ground transportation, where vehicles are magnetically levitated, guided, and propelled over elevated guideways at speeds of 300 miles per hour. Maglev is not a new concept but is, however, receiving renewed interest. The objective of this workshop was to further promote these interest by bringing together a small group of specialists in Maglev technology to discuss Maglev research needs and to identify key research issues to the development of a successful Maglev system. The workshop was organized into four sessions based on the following technical areas: Materials, Testing, and Shielding; Magnet Design and Cryogenic Systems; Propulsion and Levitation Systems; and, System Control and Integration.

  17. Introduction to the Special Issue on "State-of-the-Art Sensor Technology in Japan 2015".

    Science.gov (United States)

    Tokumitsu, Masahiro; Ishida, Yoshiteru

    2016-08-23

    This Special Issue, "State-of-the-Art Sensor Technology in Japan 2015", collected papers on different kinds of sensing technology: fundamental technology for intelligent sensors, information processing for monitoring humans, and information processing for adaptive and survivable sensor systems.[...].

  18. Some issues regarding regulatory policy, political participation, and social implications of geothermal resource development in the Imperial Valley

    Energy Technology Data Exchange (ETDEWEB)

    Green, P.S.; Steinberger, M.F.

    1976-02-01

    The early stages of geothermal resource development in the Imperial Valley have been characterized by an emphasis on the technological expertise of private developers and government officials. Government officials have created a complex array of Federal, state and county regulations to monitor the development. Local control is under the jurisdiction of the Imperial County government. The County has as its responsibility the protection of the general welfare of its residents, including any potentially adverse social, economic, or environmental impacts caused by geothermal resource development. Private developers and government officials are interested in the resources as a source of water desalination and electric power generation. An assessment of the interests and concerns of the public was made early in the development stage. In view of all these interests, it is essential in a democratic society that the various interests be identified so government can be representative of, and responsive to, those interests. Therefore, the four issues discussed in the paper are: (1) regulatory problems faced by local government officials in determining the course of development; (2) the social and political context in which the development is taking place; (3) the potential of geothermal development as perceived by community leaders and local government officials; and (4) the desirability of expanding citizen participation in geothermal decision-makingduring a period in which, as public opinion polls indicated, many citizens feel separated from government actions which may significantly affect their lives. Recommendations for regulations of geothermal resources and recommendations for improving public input into geothermal regulation are summarized in depth. (MCW)

  19. Cognitive radio: aligning the regulatory environment with the technology, a business case perspective

    NARCIS (Netherlands)

    Anker, P.D.C.; Lemstra, W.

    2012-01-01

    This paper proposes to use the perspective of the business case to deal with the alignment between the introduction of new technology and the regulatory environment. Although this perspective can be used more generally this paper deals with this perspective in the context of the alignment between

  20. Technological and regulatory aspects of quality management during the life cycle of investment and construction projects

    OpenAIRE

    Kropyvko Serhii Maksymovych

    2016-01-01

    The division of the life cycle of investment and construction projects in four phases, based on their technological features, is proposed in the article. Regulatory aspects of quality management during each phase of the life cycle of investment and construction projects are analyzed. The model of quality management during the phases of the life cycle of investment and construction project is developed.

  1. Development of Bioinformatic and Experimental Technologies for Identification of Prokaryotic Regulatory Networks

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, Charles E; McCue, Lee Ann

    2008-07-31

    The transcription regulatory network is arguably the most important foundation of cellular function, since it exerts the most fundamental control over the abundance of virtually all of a cell’s functional macromolecules. The two major components of a prokaryotic cell’s transcription regulation network are the transcription factors (TFs) and the transcription factor binding sites (TFBS); these components are connected by the binding of TFs to their cognate TFBS under appropriate environmental conditions. Comparative genomics has proven to be a powerful bioinformatics method with which to study transcription regulation on a genome-wide level. We have further extended comparative genomics technologies that we introduced over the last several years. Specifically, we developed and applied statistical approaches to analysis of correlated sequence data (i.e., sequences from closely related species). We also combined these technologies with functional genomic, proteomic and sequence data from multiple species, and developed computational technologies that provide inferences on the regulatory network connections, identifying the cognate transcription factor for predicted regulatory sites. Arguably the most important contribution of this work emerged in the course of the project. Specifically, the development of novel procedures of estimation and prediction in discrete high-D settings has broad implications for biology, genomics and well beyond. We showed that these procedures enjoy advantages over existing technologies in the identification of TBFS. These efforts are aimed toward identifying a cell’s complete transcription regulatory network and underlying molecular mechanisms.

  2. Branding technologies in the foreign policy of Ukraine: regulatory and organizational aspects

    Directory of Open Access Journals (Sweden)

    Tereshchuk Maryna Ihorivna

    2015-10-01

    Full Text Available The article analyses regulatory and organizational components of the application of branding technology as a tool of foreign policy of Ukraine. Particular attention is paid to the activities of the Ministry of Foreign Affairs of Ukraine in this sphere, as well as to the problems impeding the full implementation of the branding policy.

  3. Introduction to the Special Issue on “State-of-the-Art Sensor Technology in Japan”

    Directory of Open Access Journals (Sweden)

    Yoshiteru Ishida

    2010-05-01

    Full Text Available The combination of sensing technology with information and communication technology (ICT could serve both as global eyes that monitor the environment for environmental issues, and as local eyes that monitor humans for aging society issues. System technology is also required to form such global and local eyes. This special issue, “State-of-the-Art Sensor Technology in Japan”, contains articles and reviews related to the monitoring of humans and the environment, and the integration of sensor systems. [...

  4. Infertility and bioethical issues of the new reproductive technologies.

    Science.gov (United States)

    Herz, E K

    1989-03-01

    The scientific breakthroughs resulting in the delivery of Louise Brown in 1978 have opened the floodgates for an ongoing bioethical discussion about medically assisted reproduction. The majority in our society has accepted in vitro fertilization as an ethically justifiable procedure for infertile couples. The concern persists, however, that new reproductive technology has started us on the course of a slippery slope with potentially dire consequences for the so-created children, the traditional family, and, indeed, for society as a whole. The moral status of the embryo is the central issue in debates about such reproductive developments as the "spare" embryo, embryo freezing, embryo donation, embryo research and micromanipulation. Conflicts of interests between the adult's desire to become a parent and the welfare of the offspring are at the root of moral objections raised against manipulation of human reproduction. Extracorporal conception with the possibility for various gamete donors has also brought the long-practiced procedure of artificial insemination by donor and the potential consequences for the child into the discussion. Surrogate mothering and surrogate gestational mothering force us to redefine the age old dictum mater certa est and can render the child a helpless pawn in parental, emotional, and legal strife. Over the ages, society has through firmly established values exerted control over reproduction and acceptance of the new member in the community. Sex without reproduction was a severe blow to the highly regarded societal belief in parenting as the epitomy of life goals. Reproduction without sex through various technically feasible collaborative means further jolts fundamental traditional values and mandates their re-evaluation. Ethical belief systems are by nature highly charged and fiercely defended. Thus, in a pluralistic society, a consensus on the question "What ought to be done of all that can be done with new reproductive technologies?" is

  5. Convenient meat and meat products. Societal and technological issues.

    Science.gov (United States)

    Leroy, Frédéric; Degreef, Filip

    2015-11-01

    In past and contemporary foodscapes, meat and meat products have not only been following convenience trends, they have been at the heart of them. Historically, the first substantial demands for meat convenience must have been for the outsourcing of hunting or domestication, as well as slaughtering activities. In its turn, this prompted concerns for shelf-life stabilisation and the development of preservation strategies, such as meat fermentation. Demands for ease of preparation and consumption can be traced back to Antiquity but have gained in importance over the centuries, especially with the emergence of novel socio-cultural expectations and (perceived) time scarcity. Amongst other trends, this has led to the creation of ready meals and meat snacks and the expansion of urban fast food cultures. Additionally, contemporary requirements focus on the reduction of mental investments, via the "convenient" concealment of slaughtering, the optimisation of nutritional qualities, and the instant incorporation of more intangible matters, such as variety, hedonistic qualities, reassurance, and identity. An overview is given of the technological issues related to the creation of meat convenience, in its broadest sense, along with their societal implications. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. IPR and technological issues regarding a biopharmaceutical formulation hemoglobin.

    Science.gov (United States)

    Honrao, Chandrashekhar; Banerjee, Uttam C; Bansal, Parikshit

    2008-01-01

    Hemoglobin, the protein responsible for the red color of blood plays a very important part in 'life'- it transports oxygen, without which humans cannot survive. The idea of using purified Hemoglobin as a possible universal substitute for red blood cells has been around for almost a century. Hemoglobin formulations have important therapeutic applications, especially in case of trauma and war when requirements for blood may be very large. Manufacture of hemoglobin for use as a biopharmaceutical poses practical challenges, owing to dependence on human expired blood and fragility of the protein molecule. Biotechnology can play a critical role in breaking these barriers, by not only ensuring recombinant production of hemoglobin, but also enhancing stability of the molecule. The present article, based on a review of patents and available literature gives an insight into the IPR and technological issues involved in the commercial production of this 'life-saving' protein. There are more than 250 patents worldwide related to hemoglobin formulation, cross-linking and determination.

  7. Your idea and your university: issues in academic technology transfer.

    Science.gov (United States)

    Smith, Charles D

    2011-06-01

    Research discoveries may lead to products for commercial development. A central consideration for the researcher is how involved she or he will be in the commercialization process. In some cases, a university out-licenses the intellectual property, whereas in other cases, the investigator may want to be involved in the development process and choose to start his or her own company to develop and possibly to manufacture and sell the product. Before undertaking such a challenge, however, the investigator-turned-entrepreneur must consider a variety of issues, including career goals, financial and time commitments, potential conflicts of interest and/or commitment, start-up funding, and his or her ability to run a company or step aside to allow business experts to make necessary decisions. This paper discusses some personal considerations in deciding to start a spinout company and provides information on some of the available government grants to assist you should you decide to undertake your product's commercial development. In particular, the Small Business Innovative Research and Small Business Technology Transfer programs of federal funding agencies often are the source of early funding for new biomedical companies.

  8. Accounting for Technological Change in Regulatory Impact Analyses: The Learning Curve Technique

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Margaret [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fujita, K. Sydny [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-04-30

    Regulatory impact assessment is formally required by the U.S. and many other nations in order to help governments weigh the costs and benefits of proposed regulations, particularly as they compare to those of alternative actions and other government priorities. 1 One of the “best practices” of regulatory impact assessments, as established by the OECD, is to use estimates of costs that are grounded in economic theory. Economic theory indicates that changes in compliance costs should be expected over time as a result of factors related to technological innovation. But many U.S. regulatory impact assessments have traditionally employed a practice that is in conflict with this expectation: they take current estimates of the costs of complying with a proposed regulation and project that those costs will remain unchanged over the full time period that the regulation would be in effect.

  9. Science Technology Society Simulations: Engaging Students with Issues-based Scenarios.

    Science.gov (United States)

    Bodzin, Alec M.; Mamlok, Rachel

    2000-01-01

    Describes Science Technology and Society (STS) simulations that teach students about human experiences involving controversial issues. When students are taught using controversial and authentic issues, science instruction becomes current and engaging. (SAH)

  10. Cultural and Technological Issues and Solutions for Geodynamics Software Citation

    Science.gov (United States)

    Heien, E. M.; Hwang, L.; Fish, A. E.; Smith, M.; Dumit, J.; Kellogg, L. H.

    2014-12-01

    Computational software and custom-written codes play a key role in scientific research and teaching, providing tools to perform data analysis and forward modeling through numerical computation. However, development of these codes is often hampered by the fact that there is no well-defined way for the authors to receive credit or professional recognition for their work through the standard methods of scientific publication and subsequent citation of the work. This in turn may discourage researchers from publishing their codes or making them easier for other scientists to use. We investigate the issues involved in citing software in a scientific context, and introduce features that should be components of a citation infrastructure, particularly oriented towards the codes and scientific culture in the area of geodynamics research. The codes used in geodynamics are primarily specialized numerical modeling codes for continuum mechanics problems; they may be developed by individual researchers, teams of researchers, geophysicists in collaboration with computational scientists and applied mathematicians, or by coordinated community efforts such as the Computational Infrastructure for Geodynamics. Some but not all geodynamics codes are open-source. These characteristics are common to many areas of geophysical software development and use. We provide background on the problem of software citation and discuss some of the barriers preventing adoption of such citations, including social/cultural barriers, insufficient technological support infrastructure, and an overall lack of agreement about what a software citation should consist of. We suggest solutions in an initial effort to create a system to support citation of software and promotion of scientific software development.

  11. Information technology strategy and alignment issues in health care organizations.

    Science.gov (United States)

    Iveroth, Einar; Fryk, Pontus; Rapp, Birger

    2013-01-01

    Information technology (IT) plays a key role in public health care management because it could improve quality, efficiency, and patient care. Researchers and practitioners repeatedly contend that a health care organization's information systems strategy should be aligned with its objectives and strategies, a notion commonly known as IT alignment. Actor-related IT alignment issues in health care institutions were explored in this study. More specifically, it explores the possibility of moving beyond the current IT alignment perspective and, in so doing, explores whether IT alignment-as currently conceptualized in the dominant body of research-is sufficient for attaining improved quality, efficiency, and patient care in health care organizations. The findings are based on a qualitative and longitudinal study of six health care organizations in the Stockholm metropolitan area. The empirical data were gathered over the 2005-2011 period from interviews, a focus group, observations, and archival material. The data suggest recurrent misalignments between IT strategy and organizational strategy and operations due to the failure to deconstruct the IT artifact and to the existence of various levels of IT maturity. A more complex picture of IT alignment in health care that goes beyond the current perspective is being offered by this study. It argues that the previously common way of handling IT as a single artifact and applying one IT strategy to the entire organizational system is obsolete. MANAGERIAL IMPLICATIONS: The article suggests that considerable benefits can be gained by assessing IT maturity and its impact on IT alignment. The article also shows that there are different kinds of IT in medical care that requires diverse decisions, investments, prioritizations, and implementation approaches.

  12. Nuclear Regulatory Commission activities to prepare for reviewing license applications and issuing licenses

    Energy Technology Data Exchange (ETDEWEB)

    Uleck, R.B.; DeFino, C.V. [Nuclear Regulatory Commission, Washington, DC (United States)

    1991-12-31

    The Low-Level Radioactive Waste Policy Amendments Act of 1985 (LLRWPAA) assigned States the responsibility to provide for disposal of commercial low-level radioactive waste (LLRW) by 1993. The LLRWPAA also required the US Nuclear Regulatory Commission (NRC) to establish procedures and develop the technical review capability to process license applications for new LLRW disposal facilities. Under the LLRWPAA, NRC is required, to the extent practicable, to complete its review of an LLRW disposal facility license application within 15 months of its submittal by a State. This provision of the LLRWPAA helps ensure that NRC, in addition to protecting public health and safety and the environment, facilitates States` achievement of LLRWPAA milestones for new facility development. A timely NRC review is needed for States to accomplish their objective of having new disposal facilities in operation on the dates prescribed in the LLRWPAA. To help assure NRC and States` compliance with the provisions of the LLRWPAA, NRC has developed a licensing review strategy that includes: (1) the further development of regulatory guidance, (2) enhancement of licensing review capability, and (3) prelicensing regulatory consultation with potential applicants.

  13. Regulatory issues of natural gas distribution; Aspectos regulatorios acerca da distribuicao de gas natural

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Fabio Augusto C.C.M.; Costa, Hirdan Katarina de M. [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Faculdade de Direito

    2004-07-01

    In these past few years, natural gas in Brazil has arised as one of the alternatives for the energetic crisis suffered by the country. Such situation was one of the motives for its expansion, rising, after that, the importance of the regulation of its distribution. The regulation of canalized natural gas distribution can be found in the Federal Constitution, after Constitutional Amendment n. 05/95, in the article n. 25, para. 2nd, which say that belongs to the Federal States the concession or direct exercise of canalized natural gas services, now clearly classified as a public service. In order of these events, its imperative the analysis of natural gas distribution's public service, because it belongs to the Federal States. According to this situation, the study of the new regulatory function of the Administration and the tracing of action for the regulatory state agencies are the main goals of this work. As so, the present research aims to focus the reflexes from the actual dimension of natural gas distribution, specially referring to its regulatory statements, the limitations of state agencies, the National Petroleum Agency and the market where distribution belongs, and particularly the open access of new agents. (author)

  14. Technological and regulatory aspects of quality management during the life cycle of investment and construction projects

    Directory of Open Access Journals (Sweden)

    Kropyvko Serhii Maksymovych

    2016-12-01

    Full Text Available The division of the life cycle of investment and construction projects in four phases, based on their technological features, is proposed in the article. Regulatory aspects of quality management during each phase of the life cycle of investment and construction projects are analyzed. The model of quality management during the phases of the life cycle of investment and construction project is developed.

  15. Developing Skills for Technological Change: Some Policy Issues.

    Science.gov (United States)

    Alfthan, Torkel

    1985-01-01

    The effects of technological change on jobs and the implications for training policies are discussed here in the context of the manufacturing sector. Discusses the impact of new technologies on skills and qualifications of managers, technicians, and skilled workers. (CT)

  16. Viimsi water treatment plant for Ra removal: NORM residue/waste generation, radiation safety issues, and regulatory response

    Energy Technology Data Exchange (ETDEWEB)

    Kiisk, M.; Suursoo, S.; Realo, E.; Jantsikene, A.; Lumiste, L.; Vaeaer, K.; Isakar, K.; Koch, R. [University of Tartu (Estonia)

    2014-07-01

    values established for these radionuclides. The design and construction of the plant have underestimated the importance of aspects related to NORM accumulation and their management. Therefore, the level of Ra accumulation, ingrowth of daughter radionuclides (Th-228, Pb-210) and generation of Rn-220 and Rn-222 may pose great difficulties for the operation of the plant, especially in the case when/if the filter material is classified as NORM residue/waste with elevated radiation hazard for plant workers, public and the environment. As the first large-scale water treatment plant of the kind, there are no routine legal experience or administrative practice established in Estonia. This paper presents an overview of the operation of Viimsi Vesi Ltd. water treatment plant. The legal aspects and issues associated with management of NORM waste/residues, including classification (residue vs. waste), potential management options, optimisation of the management and radiation safety of the workers are discussed. Views of both the operator and the regulatory authority will be considered. Document available in abstract form only. (authors)

  17. Innovation in surgical technology and techniques: Challenges and ethical issues.

    Science.gov (United States)

    Geiger, James D; Hirschl, Ronald B

    2015-06-01

    The pace of medical innovation continues to increase. The deployment of new technologies in surgery creates many ethical challenges including how to determine safety of the technology, what is the timing and process for deployment of a new technology, how are patients informed before undergoing a new technology or technique, how are the outcomes of a new technology evaluated and how are the responsibilities of individual patients and society at large balanced. Ethical considerations relevant to the implementation of ECMO and robotic surgery are explored to further discussion of how we can optimize the delicate balance between innovation and regulation.

  18. Keeping It Current: Using Technology to Teach about Social Issues

    Science.gov (United States)

    Sardone, Nancy B.; Devlin-Scherer, Roberta

    2010-01-01

    In thinking about teaching nonfiction, the authors acknowledge that many contemporary and important nonfiction texts that students should be encouraged to read take up social issues that are not easy to talk about or even to think about. They discovered that combining well-chosen nonfiction on social issues with specialized digital games and other…

  19. Regulatory or regulating publics? The European Union's regulation of emerging health technologies and citizen participation.

    Science.gov (United States)

    Flear, Mark L; Pickersgill, Martyn D

    2013-01-01

    'Citizen participation' includes various participatory techniques and is frequently viewed as an unproblematic and important social good when used as part of the regulation of the innovation and implementation of science and technology. This is perhaps especially evident in debates around 'anticipatory governance' or 'upstream engagement'. Here, we interrogate this thesis using the example of the European Union's regulation of emerging health technologies (such as nanotechnology). In this case, citizen participation in regulatory debate is concerned with innovative objects for medical application that are considered to be emergent or not yet concrete. Through synthesising insights from law, regulatory studies, critical theory, and science and technology studies, we seek to cast new light on the promises, paradoxes, and pitfalls of citizen participation as a tool or technology of regulation in itself. As such we aim to generate a new vantage point from which to view the values and sociotechnical imaginaries that are both 'designed-in' and 'designed-out' of citizen participation. In so doing, we show not only how publics (do not) regulate technologies, but also how citizens themselves are regulated through the techniques of participation.

  20. Implementation Costs for Educational Technology Systems. Issue Trak: A CEFPI Brief on Educational Facility Issues.

    Science.gov (United States)

    Meeks, Glenn E.; Fisher, Ricki; Loveless, Warren

    Personnel involved in planning or developing schools lack the costing tools that will enable them to determine educational technology costs. This report presents an overview of the technology costing process and the general costs used in estimating educational technology systems on a macro-budget basis, along with simple cost estimates for…

  1. Regulatory and institutional issues impending cleanup at US Department of Energy sites: Perspectives gained from an office of environmental restoration workshop

    Energy Technology Data Exchange (ETDEWEB)

    Fallon, W E; Gephart, J M; Gephart, R E; Quinn, R D; Stevenson, L A

    1991-05-01

    The US Department of Energy's (DOE) nuclear weapons and energy operations are conducted across a nation-wide industrial complex engaged in a variety of manufacturing, processing, testing, and research and development activities. The overall mission of DOE Office of Environmental Restoration and Waste Management (EM) is to protect workers, the public, and the environment from waste materials generated by past, current, and future DOE activities and to bring the DOE complex into compliance with all applicable laws, regulations, and agreements related to health, safety, and the environment. EM addresses this broad mandate through related and interdependent programs that include corrective actions, waste operations, environmental restoration, and technology development. The EM Office of Environmental Restoration (EM-40) recognizes the importance of implementing a complex-wide process to identify and resolve those issues that may impede progress towards site cleanup. As a first step in this process, FM-40 sponsored an exercise to identify and characterize major regulatory and institutional issues and to formulate integrated action steps towards their resolution. This report is the first product of that exercise. It is intended that the exercise described here will mark the beginning of an ongoing process of issue identification, tracking, and resolution that will benefit cleanup activities across the DOE complex.

  2. Auto-disable syringes for immunization: issues in technology transfer.

    Science.gov (United States)

    Lloyd, J S; Milstien, J B

    1999-01-01

    WHO and its partners recommend the use of auto-disable syringes, "bundled" with the supply of vaccines when donor dollars are used, in all mass immunization campaigns, and also strongly advocate their use in routine immunization programmes. Because of the relatively high price of auto-disable syringes, WHO's Technical Network for Logistics in Health recommends that activities be initiated to encourage the transfer of production technology for these syringes as a means of promoting their use and enhancing access to the technology. The present article examines factors influencing technology transfer, including feasibility, corporate interest, cost, quality assurance, intellectual property considerations, and probable time frames for implementation. Technology transfer activities are likely to be complex and difficult, and may not result in lower prices for syringes. Guidelines are offered on technology transfer initiatives for auto-disable syringes to ensure the quality of the product, the reliability of the supply, and the feasibility of the technology transfer activity itself.

  3. Forecasting and Technology Management: Statistical Theory and Methodological Issues

    DEFF Research Database (Denmark)

    Madsen, Henning

    technology. The conclusion is that widespread awareness of the growing force of technology and increasing concern over its impact means that forecasting of technological development and consequences is absolutely essential in many managerial decision situations. Examples cover e.g. identification...... of directions and targets for a R and D project, monitoring of a given area by a public agency, and evaluation of the future competitive situation for a company. This paper gives a brief introduction to the field of technological forecasting especially in relation to the strategic planning process...... as the essential phase where decisions concerning introduction of new technology are taken in companies. It includes as well a description of the problems related to the marketing area and of methods applicable in practising technological forecasting....

  4. Eco Issues in Bulk Materials Handling Technologies in Ports

    Directory of Open Access Journals (Sweden)

    Nenad Zrnić

    2011-09-01

    Full Text Available This paper deals with eco issues in bulk materials handling in ports. Solid, free-flowing materials are said to be in bulk. Bulk materials handling is very difficult, because it incorporates all the features of liquids, gasses and mass solids. Energy efficiency, dust emissions in nearby environment, dust explosions, jamming, noise, handling of hazardous materials and protection of materials from contamination are issues that will be considered in this paper. Here are also presented possible solutions for some of these issues

  5. Information and Communication Technology: Gender Issues in Developing Nations

    Directory of Open Access Journals (Sweden)

    Kimberly Betz Leahy

    2003-01-01

    Full Text Available As Developing Nations seek to leverage scarce resources toward the goal of achieving a developed status they must reevaluate past practices and explore available and affordable technologies. Where in-formation and communication infrastructures are weak, use of low-cost, easily distributed technologies have proven effective. Still, many developing nations have failed to incorporate a resource in great abundance, their women, to use these new technologies to greatest advantage. This paper will address the implications of women's lack of economic and educational parity, and offer examples of how the education of women through the use of information and communication technology can enhance a nation's gross domestic product (GDP.

  6. Ethical Issues Associated with Information and Communication Technology in Counseling and Guidance

    Science.gov (United States)

    Sampson, James P., Jr.; Makela, Julia Panke

    2014-01-01

    For more than 50 years, literature on the use of information and communication technology in counseling and guidance has presented ethical issues related to the development and use of technologies in practice. This paper reviews the ethical issues raised, organizing them into three categories: Social equity, resources, and services. Career…

  7. Ethical Issues Associated with Information and Communication Technology in Counseling and Guidance

    Science.gov (United States)

    Sampson, James P., Jr.; Makela, Julia Panke

    2014-01-01

    For more than 50 years, literature on the use of information and communication technology in counseling and guidance has presented ethical issues related to the development and use of technologies in practice. This paper reviews the ethical issues raised, organizing them into three categories: Social equity, resources, and services. Career…

  8. Social Technologies for Online Learning: Theoretical and Contextual Issues

    Science.gov (United States)

    Kear, Karen; Jones, Allan; Holden, Georgina; Curcher, Mark

    2016-01-01

    Three exemplars are presented of social technologies deployed in educational contexts: wikis; a photo-sharing environment; and a social bookmarking tool. Students were found to engage with the technologies selectively, sometimes rejecting them, in the light of their prior conceptions of education. Some students (a minority in all the studies) were…

  9. Technology integration issues in a special education school in Turkey

    Directory of Open Access Journals (Sweden)

    Umit Girgin

    2011-03-01

    Full Text Available Technological advances make life easier for many students with disabilities. However, when technology isdiscussed in regard to the persons with disabilities, it usually concerns assistive technology such as hearing aids. Infact, in many contexts, information and communications technology (ICT integration can be more critical thanassistive technologies. This study was conducted in a unique school in Turkey established for children with hearingimpairment. The school uses the oral-communicative approach, emphasizing the use of hearing aids; however, thepotential for educational applications of ICT still needs further study. A research study was undertaken to establishthe opportunities for ICT integration in the classroom. The teachers were asked to complete a questionnaire on theICT integration for the school in order to establish their attitudes towards and uses of ICT in this context

  10. Transforming public utility commissions in the new regulatory environment: Some issues and ideas for managing change

    Energy Technology Data Exchange (ETDEWEB)

    Wirick, D.W.; Davis, V.W.; Burns, R.E.; Jones, D.N.

    1996-07-01

    In the face of sweeping changes in utility markets and regulatory practices, public utility commissions are being forced to change in fundamental ways--to substantially transform themselves rather than to make only incremental changes in their operations. Managing this process of radical change is complicated by the fact that for the foreseeable future some portions of utility markets (e.g., water utilities) will function much as they have before. Some envision commissions in the future that are more externally focussed, that rely more on dispute resolution than adjudicatory proceedings, that concentrate on identifying and understanding competitive markets, that are more automated, and that are more likely to question old assumptions and definitions. This report identifies the considerations commissions might apply for identifying what mix of skills or fields of experise should compromise the technical staff. Factors are also identified which point towards a sectoral arrangement of staff and those factors which point toward a functional approach.

  11. NON-TECHNOLOGICAL INNOVATION: CURRENT ISSUES AND PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    Cristina Saraiva Pereira

    2013-06-01

    Full Text Available ABSTRACTInnovationcan be considered to be a complex phenomenon including technical andnon-technical aspects. A remarkable increase in the interdisciplinary attention devoted to innovation has been noticed over the recent decades but the formal technological and economic aspects of innovation have received much more attention and have been taken into account in a far greater number of analyses, despite the great importance of the non-technological dimension of innovation.This paper attempts a review on the important subject of non-technological innovation. The main ideas on the non-technological dimension of innovation research will be highlighted, followed by an attempt to integrate diverse and disparate perspectives on the subject, to present evidence on possible generalizations and to discuss eventual research gaps and opportunities for further studies. The relationship between technological and non-technological innovation is complex and not fully understood. Among several aspects that will be covered in this paper, two specific ones will receive special attention in this brief analysis: the evidence on the impacts of non-technological innovation, and the measurements efforts that have been made concerning this phenomenon.

  12. Long-term proliferation and safeguards issues in future technologies

    Energy Technology Data Exchange (ETDEWEB)

    Keisch, B.; Auerbach, C.; Fainberg, A.; Fiarman, S.; Fishbone, L.G.; Higinbotham, W.A.; Lemley, J.R.; O' Brien, J.

    1986-02-01

    The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for which safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification.

  13. [Improving global access to new vaccines: intellectual property, technology transfer, and regulatory pathways].

    Science.gov (United States)

    Crager, Sara Eve

    2015-01-01

    The 2012 World Health Assembly Global Vaccine Action Plan called for global access to new vaccines within 5 years of licensure. Current approaches have proven insufficient to achieve sustainable vaccine pricing within such a timeline. Paralleling the successful strategy of generic competition to bring down drug prices, a clear consensus is emerging that market entry of multiple suppliers is a critical factor in expeditiously bringing down prices of new vaccines. In this context, key target objectives for improving access to new vaccines include overcoming intellectual property obstacles, streamlining regulatory pathways for biosimilar vaccines, and reducing market entry timelines for developing-country vaccine manufacturers by transfer of technology and know-how. I propose an intellectual property, technology, and know-how bank as a new approach to facilitate widespread access to new vaccines in low- and middle-income countries by efficient transfer of patented vaccine technologies to multiple developing-country vaccine manufacturers.

  14. Improving global access to new vaccines: intellectual property, technology transfer, and regulatory pathways.

    Science.gov (United States)

    Crager, Sara Eve

    2014-11-01

    The 2012 World Health Assembly Global Vaccine Action Plan called for global access to new vaccines within 5 years of licensure. Current approaches have proven insufficient to achieve sustainable vaccine pricing within such a timeline. Paralleling the successful strategy of generic competition to bring down drug prices, a clear consensus is emerging that market entry of multiple suppliers is a critical factor in expeditiously bringing down prices of new vaccines. In this context, key target objectives for improving access to new vaccines include overcoming intellectual property obstacles, streamlining regulatory pathways for biosimilar vaccines, and reducing market entry timelines for developing-country vaccine manufacturers by transfer of technology and know-how. I propose an intellectual property, technology, and know-how bank as a new approach to facilitate widespread access to new vaccines in low- and middle-income countries by efficient transfer of patented vaccine technologies to multiple developing-country vaccine manufacturers.

  15. The issue: Innovation, information technology and climate change

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-01-06

    This position paper by the Information Technology Association of Canada (ITAC) outlines the information technology community's position vis-a-vis the Federal Government's 'Climate Change Plan for Canada'. In general, the ITAC is in favour of the Government's plan, however, it asserts that the Plan falls short by not acknowledging the significant contributions that present and emerging information and communications technologies can make to the achievements of Canadian climate change goals. In this regard the paper draws attention to, and explains the significance of the actual and potential contributions made to climate change efforts by teleconferencing, video-conferencing, telecommuting, electronic commerce, and smart buildings technologies. 4 refs.

  16. Science and technology review, July-August 1998 issue

    Energy Technology Data Exchange (ETDEWEB)

    Smart, J

    1998-07-01

    On the occasion of Edward Teller's 90th birthday, S&TR has the pleasure of honoring Lawrence Livermore's co-founder and most influential scientist. Teller is known for his inventive work in physics, his concepts leading to thermonuclear explosions, and his strong stands on such issues as science education, the nation's strategic defense, the needs for science in the future, and sharing scientific information. The articles in this issue also show him, as always, tirelessly moving forward with his new and changing interests.

  17. special issue: Technology transfer in United States universities

    OpenAIRE

    Ann-Charlotte Fridh; Bo Carlsson

    2002-01-01

    This paper examines the role of offices of technology transfer (OTT) in 12 U.S. universities in 1998 in commercializing research results in the form of patents, licenses, and start-ups of new companies. We study the organization and place of OTTs within the university structure, the process of technology transfer, and the staffing and funding of the office. Data were collected through a mail questionnaire followed up through telephone interviews. We also conducted a statistical analysis of da...

  18. Privacy, legal and regulatory issues in the management of the internet of things for South Africa

    CSIR Research Space (South Africa)

    Dlodlo, N

    2014-11-01

    Full Text Available The internet of things (IoT) is a concept which has its roots in sensing, networking and information processing approaches. It enables data exchange between devices, services and people. As a result of the integration of these technologies, big data...

  19. Progress and Updates of Regulatory Challenges and Safety Issues in Korea during Three Years after Fukushima Accident

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Eal; Kim, Kyun Tae [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-10-15

    Before the public fear on radiation risk caused by neighboring country's severe accident disappeared, a series of nuclear safety issues last 3 years made a few reactors shut down and the public trust much lower than before. Because of these scandals such as cover-ups, forged certificated items, corruption of manager of licensee and so on, many efforts made during three year after Fukushima accident on improving the nuclear safety were invalidated and even regulators as well as operators have been sharply criticized for its responsibility and transparency. This paper shares information on the progress and uprates achieved in Korea so far in connection with the safety issues caused during last 3 years and actions taken by the regulatory body. Before the public fear on radiation risk caused by neighboring country's severe accident disappeared, a series of nuclear safety issues last 3 years made a few reactors shut down and the public trust much lower than before. Because of these scandals such as cover-ups, forged certificated items, corruption of manager of licensee and so on, many efforts made during three year after Fukushima accident on improving the nuclear safety were invalidated and even regulators as well as operators have been sharply criticized for its responsibility and transparency.

  20. Formation of non-extractable pesticide residues: observations on compound differences, measurement and regulatory issues

    Energy Technology Data Exchange (ETDEWEB)

    Mordaunt, Catriona J.; Gevao, Bondi; Jones, Kevin C.; Semple, Kirk T

    2005-01-01

    Six major use pesticides (Atrazine, Dicamba, Isoproturon, Lindane, Paraquat and Trifluralin) with differing physico-chemical properties were evaluated for the significance of 'bound' or non extractable residue formation. Investigations were carried out in purpose-built microcosms where mineralization, volatilisation, 'soil water' extractable and organic solvent extractable residues could be quantified. Extractable residues were defined as those accessible by sequential extraction where the solvent used became increasingly non-polar. Dichloromethane was the 'harshest' solvent used at the end of the sequential extraction procedure. {sup 14}C-labelled volatilised and {sup 14}CO{sub 2} fractions were trapped on exit from the microcosm. The pesticides were categorised into 3 classes based on their behaviour. (i) Type A (Atrazine, Lindane and Trifluralin) in which ring degradation was limited as was the formation of non-extractable residues; the remainder of the {sup 14}C-activity was found in the extractable fraction. (ii) Type B (Dicamba and Isoproturon) in which approximately 25% of the {sup 14}C-activity was mineralised and a large portion was found in the non-extractable fraction after 91 days. Finally, Type C (Paraquat) in which almost all of the {sup 14}C-activity was quickly incorporated into the non-extractable fraction. The implications of the data are discussed, with respect to the variability and significance of regulatory aspects of non-extractable residues.

  1. Public health surveillance data: legal, policy, ethical, regulatory, and practical issues.

    Science.gov (United States)

    Bernstein, Amy B; Sweeney, Marie Haring

    2012-07-27

    In the United States, data systems are created by the ongoing, systematic collection of health, demographic, and other information through federally funded national surveys, vital statistics, public and private administrative and claims data, regulatory data, and medical records data. Certain data systems are designed to support public health surveillance and have used well-defined protocols and standard analytic methods for assessing specific health outcomes, exposures, or other endpoints. However, other data systems have been designed for a different purpose but can be used by public health programs for surveillance. Several public health surveillance programs rely substantially on others' data systems. An example of data used for surveillance purposes but collected for another reason is vital statistics data. CDC's National Center for Health Statistics (NCHS) purchases, aggregates, and disseminates vital statistics (birth and death rates) that are collected at the state level. These data are used to understand disease burden, monitor trends, and guide public health action. Administrative data also can be used for surveillance purposes (e.g., Medicare and Social Security Disability data that have been linked to survey data to monitor changes in health and health-care use over time).

  2. Aspartame, low-calorie sweeteners and disease: regulatory safety and epidemiological issues.

    Science.gov (United States)

    Marinovich, Marina; Galli, Corrado L; Bosetti, Cristina; Gallus, Silvano; La Vecchia, Carlo

    2013-10-01

    Aspartame is a synthetic sweetener that has been used safely in food for more than 30 years. Its safety has been evaluated by various regulatory agencies in accordance with procedures internationally recognized, and decisions have been revised and updated regularly. The present review summarizes the most relevant conclusions of epidemiological studies concerning the use of low-calorie sweeteners (mainly aspartame), published between January 1990 and November 2012. In the Nurses' Health study and the Health Professionals Followup study some excess risk of Hodgkin lymphoma and multiple myeloma was found in men but not in women; no association was found with leukemia. In the NIH-AARP Diet and Health Study, there was no association between aspartame and haematopoietic neoplasms. US case-control studies of brain and haematopoietic neoplasms also showed no association. The NIH-AARP Diet and Health Study and case-control studies from California showed no association with pancreatic cancer, and a case-control study from Denmark found no relation with breast cancer risk. Italian case-control studies conducted in 1991-2008 reported no consistent association for cancers of the upper aerodigestive tract, digestive tract, breast, endometrium, ovary, prostate, and kidney. Low calorie sweeteners were not consistently related to vascular events and preterm deliveries.

  3. Forecasting and Technology Management: Statistical Theory and Methodological Issues

    DEFF Research Database (Denmark)

    Madsen, Henning

    The degree of development in the technical capability of many new devices and materials over their predecessors often is in multiples of improvement. These gains in performance are so great that they abruptly and drastically alter the means, effects, time, or costs of doing things. Thus, they dis......The degree of development in the technical capability of many new devices and materials over their predecessors often is in multiples of improvement. These gains in performance are so great that they abruptly and drastically alter the means, effects, time, or costs of doing things. Thus...... technology. The conclusion is that widespread awareness of the growing force of technology and increasing concern over its impact means that forecasting of technological development and consequences is absolutely essential in many managerial decision situations. Examples cover e.g. identification...

  4. Progress and issues in polycrystalline thin-film PV technologies

    Energy Technology Data Exchange (ETDEWEB)

    Zweibel, K.; Ullal, H.S.; Roedern, B. von [National Renewable Energy Lab., Golden, CO (United States)

    1996-05-01

    Substantial progress has occurred in polycrystalline thin-film photovoltaic technologies in the past 18 months. However, the transition to first-time manufacturing is still under way, and technical problems continue. This paper focuses on the promise and the problems of the copper indium diselenide and cadmium telluride technologies, with an emphasis on continued R&D needs for the near-term transition to manufacturing and for next-generation improvements. In addition, it highlights the joint R&D efforts being performed in the U.S. Department of Energy/National Renewable Energy Laboratory Thin-Film Photovoltaic Partnership Program.

  5. Regulatory issues related to functional foods and natural health products in Canada: possible implications for manufacturers of conjugated linoleic acid.

    Science.gov (United States)

    Fitzpatrick, Kelley C

    2004-06-01

    The Canadian Food and Drugs Act and Regulations, through its definitions of food and drug, currently restricts health-related claims for foods, food ingredients, and natural health products (NHPs). Over the past few decades, scientific research has led to a large body of information that demonstrates the benefits for health of many food and NHP ingredients. Health Canada recognized the constraints of the current regulatory environment and started to develop regulations related to the allowance of health claims for functional foods and NHPs, including those foods and NHPs that would contain conjugated linoleic acid isomers. Health Canada has 3 initiatives under way in the area of health claims for foods: 1) to adopt the generic health claims of the United States within a Canadian context, 2) to develop scientific standards of evidence and a guidance document for supporting the validity of product-specific claims, and 3) to develop an overall regulatory framework for functional foods. In 2000, Health Canada announced approval for the use of 5 generic diet-related health claims: sodium and hypertension, calcium and osteoporosis, saturated and trans fat and cholesterol and coronary artery disease, fruits and vegetables and cancer, and sugar alcohols and dental caries. Under a separate initiative, Natural Health Products Regulations were published in the Canada Gazette Part II on June 18, 2003. The NHP Regulations came into force on January 1, 2004, with a transition period ranging from 2 y (for site licensing) to 6 y (for product licensing, for products already issued a drug identification number).

  6. Regulatory Issues and Challenges in Developing Seismic Source Characterizations for New Nuclear Power Plant Applications in the US

    Science.gov (United States)

    Fuller, C. W.; Unruh, J.; Lindvall, S.; Lettis, W.

    2009-05-01

    further complicated by: (1) a given applicant's uncertainty in how to revise the EPRI-SOG model, which was developed using a process similar to that dictated by SSHAC for a level 3 or 4 study, without conducting a resource-intensive SSHAC level 3 or higher study for their respective application; and (2) a lack of guidance from the NRC on acceptable methods of demonstrating that new data, interpretations, and opinions are adequately represented within the EPRI-SOG model. Partly because of these issues, initiative was taken by the nuclear industry, NRC and DOE to develop a new base PSHA model for the central and eastern US. However, this new SSC model will not be completed for several years and does not resolve many of the fundamental regulatory and philosophical issues that have been raised during the current round of applications. To ensure regulatory stability and to provide accurate estimates of hazard for nuclear power plants, a dialog must be started between regulators and industry to resolve these issues. Two key issues that must be discussed are: (1) should new data and new interpretations or opinions of old data be treated differently in updated SSCs, and if so, how?; and (2) how can new data or interpretations developed by a small subset of the technical community be weighed against and potentially combined with a SSC model that was originally developed to capture the "center, body and range" of the technical community?

  7. [Health issues and regulatory aspects of the use of ultrasound in physiotherapy].

    Science.gov (United States)

    Giliberti, Claudia; Pozzi, Roberta; Calicchia, Paola; Polichetti, Alessandro

    2015-01-01

    The use of ultrasounds in medicine requires, like all physical agents potentially harmful to human health, an accurate assessment of the risks to the health of patients. The nature and extent of these risks depend on exposure levels which in turn are differentiated according to the specific diagnostic or therapeutic applications. Intermediate exposure levels are associated to physiotherapic applications. To analyze specific issues relating to the effectiveness and safety of physiotherapic treatments, a review of the scientific literature and technical standards was carried out. At present, the actual effectiveness of ultrasound physiotherapy is still far from being clearly assessed: further clinical and experimental studies are needed in order to optimize therapies, determining the benefits and risks of treatments and deepening the understanding of the action mechanisms of the physical agent, even on the basis of a better characterization of those physical quantities mostly significant for biological effects. The examination of technical standards defining the security requirements of the equipment allowed the identification of some critical issues; on these bases some proposals are suggested for the improvement of quality and safety of treatments.

  8. Information systems outsourcing issues in the communication technology sector

    CSIR Research Space (South Africa)

    Smuts, H

    2010-03-01

    Full Text Available (CT) sector in South Africa through a survey among organisations in this sector. The survey results are compared to findings in similar studies in other markets and unique contributors to IS outsourcing issues in the South African context..., knowledge and capabilities found outside its bounds (Power et al., 2006, Edersheim, 2007). Outsourcing as a business practice is flourishing in almost every domain and organisations are outsourcing functional areas such as information systems, marketing...

  9. Development of neuroleptic agents: pharmacogenetics and current safety issues of regulatory concern.

    Science.gov (United States)

    Shah, Rashmi

    2002-12-01

    The development of safe and effective new drug treatments for schizophrenia poses a challenging task. This class of drugs is known to be associated with a wide range of serious and troublesome safety problems that include neurological, cardiac, endocrine, and metabolic side effects. Many of these drugs have a narrow therapeutic index and generate metabolites that often have their own unique pharmacological profile different from the parent compound. These features make it imperative that the optimal dose schedules for neuroleptic drugs are carefully characterized. Many of these drugs are metabolized by cytochrome P450 enzymes, which show genetic polymorphism and a bi modal distribution within the population, A significant subset of the population cannot eliminate these drugs as effectively as the majority. This brings an added dimension of complexity in characterizing the dose and individualizing therapy. Many neuroleptic agents are proarrhythmic with an adverse effect on cardiac repolarization. They are prone to prolonging the QT interval and inducing torsade de pointes. Given the potentially fatal outcome of this ventricular tachyarrhythmia, drug development programs need to ensure that the proarrhythmic potential of any new neuroleptic agent is thoroughly explored and its proarrhythmic risk characterized. The clinical use of many of these drugs is further troubled by their high potential for drug-drug interactions. These too need to be adequately investigated during development The approval and the labeling of a new neuroleptic agent require a careful regulatory assessment of its risk/benefit ratio in comparison with the available alternatives. Their safe and effective use in routine clinical practice depends on careful attention to prescribing information, especially the contraindications, precautions, and patient-monitoring requirements.

  10. Technology and human issues in reusing learning objects

    NARCIS (Netherlands)

    Collis, Betty; Strijker, Allard

    2004-01-01

    Reusing learning objects is as old as retelling a story or making use of libraries and textbooks, and in electronic form has received an enormous new impetus because of the World Wide Web and Web technologies. Are we at the brink of changing the "shape and form of learning, ... of being able to trul

  11. Key Issue: Recruiting Science, Technology, Engineering, and Mathematics (STEM) Teachers

    Science.gov (United States)

    McGraner, Kristin L.

    2009-01-01

    A STEM teacher is one who teaches in the fields of science, technology, engineering, and mathematics. In K-12 schooling, most STEM teachers instruct mathematics and science classes, which continue to be critical shortage areas. As part of a comprehensive human capital strategy, designing recruitment initiatives to attract qualified STEM teachers…

  12. Technology and Human Issues in Reusing Learning Objects.

    NARCIS (Netherlands)

    Collis, Betty; Strijker, Allard

    2004-01-01

    Reusing learning objects is as old as retelling a story or making use of libraries and textbooks, and in electronic form has received an enormous new impetus because of the World Wide Web and Web technologies. Are we at the brink of changing the "shape and form of learning, ... of being able to trul

  13. Data Protection Issues in Higher Education with Technological Advancements

    Science.gov (United States)

    McKelvey, Nigel

    2014-01-01

    Adhering to laws whilst working or studying in an educational establishment is often fraught with challenges. The Irish Data Protection Act 1988 (Amendment 2003) strives to protect the individual where their personal data is potentially being abused. The advancements in technologies have facilitated educational establishments by improving…

  14. Integrating Technology in a Geometry Classroom: Issues for Teaching.

    Science.gov (United States)

    Pokay, Patricia A.; Tayeh, Carla

    1997-01-01

    Based on a college-level geometry course, presents practical suggestions for integrating exploratory computer applications into the mathematics classroom. Reveals that students need more experimental time with technology to reduce anxiety, and assessments need to be developed and implemented to tap the outcomes of problem solving and higher level…

  15. Women and Information Technology: Framing Some Issues for Education.

    Science.gov (United States)

    Damarin, Suzanne K.

    1992-01-01

    Discusses relationships among technology, women, and education. Presents three views of the computer's future: (1) the robot as superior human; (2) the cyborg; and (3) the human-computer dyad. Discusses effects that the computer has had upon work and school, particularly for women and at risk and nonliterate students. (SG)

  16. Regulatory Initiatives for Control and Release of Technologically Enhanced Naturally-Occurring Radioactive Materials

    Energy Technology Data Exchange (ETDEWEB)

    Egidi, P.V.

    1999-03-02

    Current drafts of proposed standards and suggested State regulations for control and release of technologically-enhanced naturally-occurring radioactive material (TENORM), and standards for release of volumetrically-contaminated material in the US are reviewed. These are compared to the recommendations of the International Atomic Energy Association (IAEA) Safety Series and the European Commission (EC) proposals. Past regulatory efforts with respect to TENORM in the US dealt primarily with oil-field related wastes. Currently, nine states (AK, GA, LA, MS, NM, OH, OR SC, TX) have specific regulations pertaining to TENORM, mostly based on uranium mill tailings cleanup criteria. The new US proposals are dose- or risk-based, as are the IAEA and EC recommendations, and are grounded in the linear no threshold hypothesis (LNT). TENORM wastes involve extremely large volumes, particularly scrap metal and mine wastes. Costs to control and dispose of these wastes can be considerable. The current debate over the validity of LNT at low doses and low dose rates is particularly germane to this discussion. Most standards setting organizations and regulatory agencies base their recommendations on the LNT. The US Environmental Protection Agency has released a draft Federal Guidance Report that recommends calculating health risks from low-level exposure to radionuclides based on the LNT. However, some scientific and professional organizations are openly questioning the validity of LNT and its basis for regulations, practices, and costs to society in general. It is not clear at this time how a non-linear regulatory scheme would be implemented.

  17. Subsurface Contaminant Focus Area: Monitored Natural Attenuation (MNA)--Programmatic, Technical, and Regulatory Issues

    Energy Technology Data Exchange (ETDEWEB)

    Krupka, Kenneth M.; Martin, Wayne J.

    2001-07-23

    Natural attenuation processes are commonly used for remediation of contaminated sites. A variety of natural processes occur without human intervention at all sites to varying rates and degrees of effectiveness to attenuate (decrease) the mass, toxicity, mobility, volume, or concentration of organic and inorganic contaminants in soil, groundwater, and surface water systems. The objective of this review is to identify potential technical investments to be incorporated in the Subsurface Contaminant Focus Area Strategic Plan for monitored natural attenuation. When implemented, the technical investments will help evaluate and implement monitored natural attenuation as a remediation option at DOE sites. The outcome of this review is a set of conclusions and general recommendations regarding research needs, programmatic guidance, and stakeholder issues pertaining to monitored natural attenuation for the DOE complex.

  18. MIIT Issued Industrial Key Generic Technology Development Guidelines (2011)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In order to make full use of social resources, guide conducts of market subject, lead the developing direction of industrial key generic technology, promote industrial technology advance and realize transformation, upgrading and structural optimization of industry and communications industry, on July 1, the Ministry of Industry and Information Technology (MIIT) issued Industrial Key Generic Technology Development Guidelines (2011) (Gong Xin Bu Ke [2011] No.320),

  19. Assistive Technologies and Issues Relating to Privacy, Ethics and Security

    Science.gov (United States)

    Martin, Suzanne; Bengtsson, Johan E.; Dröes, Rose-Marie

    Emerging technologies provide the opportunity to develop innovative sustainable service models, capable of supporting adults with dementia at home. Devices range from simple stand-alone components that can generate a responsive alarm call to complex interoperable systems that even can be remotely controlled. From these complex systems the paradigm of the ubiquitous or ambient smart home has emerged, integrating technology, environmental design and traditional care provision. The service context is often complex, involving a variety of stakeholders and a range of interested agencies. Against this backdrop, as anecdotal evidence and government policies spawn further innovation it is critical that due consideration is given to the potential ethical ramifications at an individual, organisational and societal level. Well-grounded ethical thinking and proactive ethical responses to this innovation are required. Explicit policy and practice should therefore emerge which engenders confidence in existing supported living option schemes for adults with dementia and informs further innovation.

  20. Technology and the issue of cost/benefit in diabetes.

    Science.gov (United States)

    Giannini, Cosimo; Mohn, Angelika; Chiarelli, Francesco

    2009-09-01

    Diabetes mellitus is the most common endocrine disease in childhood and adolescence. Type 1 diabetes accounts for over 90% of diabetes in children. During the past decades, epidemiological studies have clearly shown a worldwide increase in the incidence of both type 1 and type 2 diabetes in many countries. The worldwide incidence of diabetes and especially the diabetes-related complications highlight the relevant economic burden of this disease. In fact, its costs affect health services, national productivity as well as individuals and families. Hospital in-patient costs for the treatment of complications are the largest single contributor to direct healthcare costs. Anyway, many of these complications and, therefore, their costs, as well as most of the indirect costs, are partially or completely preventable. In fact, intensive therapy, directed at controlling blood glucose, blood pressure and lipid levels, has been shown to be cost effective in that, although initial costs are high, longer term costs decrease as a result of delayed or prevented complications. From this point of view, technological advances have provided new therapeutic options to achieve metabolic control as close to normal as possible in children and adolescents with diabetes. In fact, the relevant technological devices that have been adopted till now, if adequately utilized, should allow patients to achieve intensive management with improved metabolic control, quality of life as well as reduced mortality and morbidity. However, new technologies are not a panacea, and the benefit they provide can be completely achieved only if adequately and especially individually determined. Furthermore, it is inevitable that new modalities of treatment for people with diabetes will be considered critically by healthcare planners and providers in the prevailing global environment of increasing costs of medical care and pressure for rational allocation of resources. Therefore, new technologically derived devices

  1. Ethical and social issues of embryonic stem cell technology.

    Science.gov (United States)

    Cregan, K

    2005-02-01

    Therapeutic cloning is debated as a cure for a host of diseases in the developed world. The likely source for the materials for therapeutic cloning, human ova, would be poor women and women from the developing world. The ethics and potential social consequences inherent in this technology are fraught and encourage the com modification and abstraction of one of the fundamental conditions of human life.

  2. Regulatory analysis for the resolution of Generic Safety Issue 29: Bolting degradation or failure in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Chang, T.Y.

    1991-09-01

    Generic Safety Issue (GSI)-29 deals with staff concerns about public risk due to degradation or failure of safety-related bolting in nuclear power plants. The issue was initiated in November 1982. Value-impact studies of a mandatory program on safety-related bolting for operating plants were inconclusive: therefore, additional regulatory requirements for operating plants could not be justified in accordance with provisions of 10 CFR 50.109. In addition, based on operating experience with bolting in both nuclear and conventional power plants, the actions already taken through bulletins, generic letters, and information notices, and the industry-proposed actions, the staff concluded that a sufficient technical basis exists for the resolution of GSI-29. The staff further concluded that leakage of bolted pressure joints is possible but catastrophic failure of a reactor coolant pressure boundary joint that will lead to significant accident sequences is highly unlikely. For future plants, it was concluded that a new Standard Review Plant section should be developed to codify existing bolting requirements and industry-developed initiatives. 9 refs., 1 tab.

  3. Ethical and regulatory issues with conducting sexuality research with LGBT adolescents: a call to action for a scientifically informed approach.

    Science.gov (United States)

    Mustanski, Brian

    2011-08-01

    Lesbian, gay, bisexual, and transgender (LGBT) adolescents experience disparities in mental and sexual health. There is also a lack of research on this population relative to other adolescents, which limits our ability to effectively address these health disparities. Researchers may unfortunately avoid conducting research with this population because of anticipated or actual experiences with difficulties in obtaining IRB approval. A case example is provided to illustrate the ethical and regulatory issues related to research with LGBT adolescents. Relevant U.S. federal and local regulations related to research on sexual and mental health with adolescents is then reviewed. Data are presented demonstrating that requiring parental consent for LGBT youth under age 18 would likely alter study result. Data are also presented on participants' appraisals of the risks and discomforts associated with research participation. The provision of such empirical data on the risks of research participation is consistent with the goal of moving the IRB process of risk/benefit assessment from being entirely subjective to being evidence-based. Finally, recommendations are provided on how to approach these issues in IRB applications and investigators are called to help to build a corpus of scholarship that can advance empirical knowledge in this area.

  4. Medical photography: current technology, evolving issues and legal perspectives.

    Science.gov (United States)

    Harting, M T; DeWees, J M; Vela, K M; Khirallah, R T

    2015-04-01

    Medical photographic image capture and data management has undergone a rapid and compelling change in complexity over the last 20 years. This is because of multiple factors, including significant advances in ease of photograph capture, alongside an evolution of mechanisms of data portability/dissemination, combined with governmental focus on health information privacy. Literature to guide medical, legal, governmental and business professionals when dealing with issues related to medical photography is virtually nonexistent. Herein, we will address the breadth of uses of medical photography, device properties/specific devices utilised for image capture, methods of data transfer and dissemination and patient perceptions and attitudes regarding photography in a medical setting. In addition, we will address the legal implications, including legal precedent, copyright and privacy law, informed consent, protected health information and the Health Insurance Portability and Accountability Act (HIPAA), as they pertain to medical photography.

  5. Non-inferiority clinical trials: Practical issues and current regulatory perspective

    Directory of Open Access Journals (Sweden)

    Sandeep K Gupta

    2011-01-01

    Full Text Available Non-inferiority clinical trials are being performed with an increasing frequency now-a-days, because it helps in finding a new treatment that have approximately the same efficacy, but may offer other benefits such as better safety profile. Non-inferiority clinical trials aim to demonstrate that the test product is no worse than the comparator by more than a pre-specified small amount. There are several fundamental differences between non-inferiority and superiority trials. Some practical issues concerning the non-inferiority trials are assay sensitivity, choice of the non-inferiority margin, sample size estimation, choice of active-control, and analysis of non-inferiority clinical trials. For serious infections such as hospital-acquired bacterial pneumonia/ventilator-associated bacterial pneumonia, community-acquired bacterial pneumonia, and acute bacterial skin and skin structure infections, the United States Food and Drug Administration (US FDA has recently recommended that it is possible to define a reliable and consistent estimate of the efficacy of active treatment relative to placebo from available data, which can serve as the basis for defining a new inferiority margin for an active-controlled, non-inferiority trial. But for some indications with a high rate of resolution without antibacterial drug therapy such as acute bacterial sinusitis (ABS, acute bacterial exacerbation of chronic bronchitis (ABECB, and acute bacterial otitis media (ABOM, the US FDA has recommended that the available data will not support the use of a non-inferiority design and other trial designs (i.e., superiority designs should be used to provide the evidence of effectiveness in these three indications.

  6. Some Issues on Computer Networks: Architecture and Key Technologies

    Institute of Scientific and Technical Information of China (English)

    Guan-Qun Gu; Jun-Zhou Luo

    2006-01-01

    The evolution of computer networks has experienced several major steps, and research focus of each step has been kept changing and evolving, from ARPANET to OSI/RM, then HSN (high speed network) and HPN (high performance network). During the evolution, computer networks represented by Internet have made great progress and gained unprecedented success. However, with the appearance and intensification of tussle, along with the three difficult problems (service customizing, resource control and user management) of modern network, it is found that traditional Internet and its architecture no longer meet the requirements of next generation network. Therefore, it is the next generation network that current Internet must evolve to. With the mindset of achieving valuable guidance for research on next generation network, this paper firstly analyzes some dilemmas facing current Internet and its architecture, and then surveys some recent influential research work and progresses in computer networks and related areas, including new generation network architecture, network resource control technologies, network management and security, distributed computing and middleware,wireless/mobile network, new generation network services and applications, and foundational theories on network modeling.Finally, this paper concludes that within the research on next generation network, more attention should be paid to the high availability network and corresponding architecture, key theories and supporting technologies.

  7. Land and Resource Management Issues Relevant to Deploying In-Situ Thermal Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Keiter, Robert; Ruple, John; Tanana, Heather; Kline, Michelle

    2011-02-28

    Utah is home to oil shale resources containing roughly 1.3 trillion barrels of oil equivalent and our nation’s richest oil sands resources. If economically feasible and environmentally responsible means of tapping these resources can be developed, these resources could provide a safe and stable domestic energy source for decades to come. In Utah, oil shale and oil sands resources underlay a patchwork of federal, state, private, and tribal lands that are subject to different regulatory schemes and conflicting management objectives. Evaluating the development potential of Utah’s oil shale and oil sands resources requires an understanding of jurisdictional issues and the challenges they present to deployment and efficient utilization of emerging technologies. The jurisdictional patchwork and divergent management requirements inhibit efficient, economic, and environmentally sustainable development. This report examines these barriers to resource development, methods of obtaining access to landlocked resources, and options for consolidating resource ownership. This report also examines recent legislative efforts to wrest control of western public lands from the federal government. If successful, these efforts could dramatically reshape resource control and access, though these efforts appear to fall far short of their stated goals. The unintended consequences of adversarial approaches to obtaining resource access may outweigh their benefits, hardening positions and increasing tensions to the detriment of overall coordination between resource managers. Federal land exchanges represent a more efficient and mutually beneficial means of consolidating management control and improving management efficiency. Independent of exchange proposals, resource managers must improve coordination, moving beyond mere consultation with neighboring landowners and sister agencies to coordinating actions with them.

  8. Land and Resource Management Issues Relevant to Deploying In-Situ Thermal Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Keiter, Robert [Univ. of Utah, Salt Lake City, UT (United States); Ruple, John [Univ. of Utah, Salt Lake City, UT (United States); Tanana, Heather [Univ. of Utah, Salt Lake City, UT (United States); Kline, Michelle [Univ. of Utah, Salt Lake City, UT (United States)

    2011-01-01

    Utah is home to oil shale resources containing roughly 1.3 trillion barrels of oil equivalent and our nation’s richest oil sands resources. If economically feasible and environmentally responsible means of tapping these resources can be developed, these resources could provide a safe and stable domestic energy source for decades to come. In Utah, oil shale and oil sands resources underlay a patchwork of federal, state, private, and tribal lands that are subject to different regulatory schemes and conflicting management objectives. Evaluating the development potential of Utah’s oil shale and oil sands resources requires an understanding of jurisdictional issues and the challenges they present to deployment and efficient utilization of emerging technologies. The jurisdictional patchwork and divergent management requirements inhibit efficient, economic, and environmentally sustainable development. This report examines these barriers to resource development, methods of obtaining access to landlocked resources, and options for consolidating resource ownership. This report also examines recent legislative efforts to wrest control of western public lands from the federal government. If successful, these efforts could dramatically reshape resource control and access, though these efforts appear to fall far short of their stated goals. The unintended consequences of adversarial approaches to obtaining resource access may outweigh their benefits, hardening positions and increasing tensions to the detriment of overall coordination between resource managers. Federal land exchanges represent a more efficient and mutually beneficial means of consolidating management control and improving management efficiency. Independent of exchange proposals, resource managers must improve coordination, moving beyond mere consultation with neighboring landowners and sister agencies to coordinating actions with them.

  9. National Technology Standards for K-12 Schools: A Case Study of Unresolved Issues in Public Relations

    Science.gov (United States)

    Mullen, Carol A.; Kealy, William A.; Sullivan, Ashley

    2004-01-01

    This article addresses an important need--the dissemination of information relating to technology as a public relations tool--and the associated exigency for administrator and teacher technology training. Specifically, we identify the increased expectations for the performance of school leaders and teachers, as well as unresolved issues in public…

  10. Research Trends and Issues in Educational Technology: A Content Analysis of TOJET (2008-2011)

    Science.gov (United States)

    Bozkaya, Mujgan; Aydin, Irem Erdem; Kumtepe, Evrim Genc

    2012-01-01

    This study has been conducted to evaluate the contents of articles published in the Turkish Online Journal of Educational Technology (TOJET) between 2008 and 2011. General aim of the study is to review on what trends, issues and research methods on which studies of educational technology have concentrated in the last four years. Thus, articles…

  11. A Detailed Analysis over Some Important Issues towards Using Computer Technology into the EFL Classrooms

    Science.gov (United States)

    Gilakjani, Abbas Pourhosein

    2014-01-01

    Computer technology has changed the ways we work, learn, interact and spend our leisure time. Computer technology has changed every aspect of our daily life--how and where we get our news, how we order goods and services, and how we communicate. This study investigates some of the significant issues concerning the use of computer technology…

  12. Issues in Integrating Information Technology in Learning and Teaching EFL: The Saudi Experience

    Science.gov (United States)

    Al-Maini, Yousef Hamad

    2013-01-01

    The Saudi education system is facing a climate of change characterized by an interest in integrating new technology and educational approaches to improve teaching and learning. In this climate, the present paper explores the issues in integrating information technology in learning and teaching English as a foreign language (EFL) in government…

  13. Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions

    Science.gov (United States)

    Syed, Mahbubur Rahman, Ed.

    2009-01-01

    The emerging field of advanced distance education delivers academic courses across time and distance, allowing educators and students to participate in a convenient learning method. "Methods and Applications for Advancing Distance Education Technologies: International Issues and Solutions" demonstrates communication technologies, intelligent…

  14. A System Analysis for Determining Alternative Technological Issues for the Future

    Science.gov (United States)

    Magistrale, V. J.; Small, J.

    1967-01-01

    A systems engineering methodology is provided, by which future technological ventures may be examined utilizing particular national, corporate, or individual value judgments. Three matrix analyses are presented. The first matrix is concerned with the effect of technology on population increase, war, poverty, health, resources, and prejudice. The second matrix explores an analytical technique for determining the relative importance of different areas of technology. The third matrix explores how an individual or corporate entity may determine how its capability may be used for future technological opportunities. No conclusions are presented since primary effort has been placed on the methodology of determining future technological issues.

  15. TRENDS AND ISSUES: A REVIEW OF STUDIES RELATED TO TECHNOLOGY USAGE IN EARLY CHILDHOOD EDUCATION

    OpenAIRE

    Elif ÖZTÜRK YILMAZTEKİN; OLGAN, Refika

    2013-01-01

    This paper describes types of technology studies that have been conducted related to young children’s early education. A systematic review of studies was undertaken using EBSCOhost, Blackwell Synergy, and ScienceDirect databases, to identify all studies published between 2003 and 2009 according to specific criteria. The studies were selected on the basis of the following three issues: (1) the role of technology in children’s development, (2) the role of technology in teachers’ teaching pract...

  16. Critical issues in urban technologies for sustainable development: The case of water infrastructure in Mexico City

    Energy Technology Data Exchange (ETDEWEB)

    Zoreda-Lozano, J.J.; Castaneda, V. [Univ. Autonoma Metropolitana-Xochimilco (Mexico)

    1998-11-01

    This paper presents a general approach to the structural links between urban technologies for water use and sustainable development in Mexico City. These links belong to the public domain and are sufficiently generalizable so as to be expanded and modified to suit other technologies in similar contexts. They offer a convenient backdrop against which to meaningfully address critical technological issues that affect the performance of urban settlements as well as their biophysical environments.

  17. Issues of doing gender and doing technology - Music as an innovative theme for technology education

    Science.gov (United States)

    Thaler, A.; Zorn, I.

    2010-08-01

    This paper presents the concept and results of the research project 'Engineer Your Sound!' (2008-2009). It aimed at exploring whether interdisciplinary, innovative teaching/learning settings in the fields of technology and digital media can be used to give pupils the opportunities to experiment and discover their technical potential, skills, interests and talents and if music technology could offer such an appealing context. The paper explains how technology and why gender need to be addressed when planning to raise young people's interest in technology but questions if interest in technology is mainly influenced by gender. The paper explores through ethnographic research how pupils' technological competencies and interests have developed during the course of a technology-related project. Results of the analysis explain how music technology can serve as a suitable theme with the potential to increase both males' and females' interest in technology.

  18. From road to lab to math: the co-evolution of technological, regulatory, and organizational innovations for automotive crash testing.

    Science.gov (United States)

    Leonardi, Paul M

    2010-04-01

    Today, in the midst of economic crisis, senior executives at US automakers and influential industry analysts frequently reflect on the progression that safety testing has taken from the crude trials done on the road, to controlled laboratory experiments, and to today's complex math-based simulation models. They use stories of this seemingly linear and natural sequence to justify further investment in simulation technologies. The analysis presented in this paper shows that change in the structures of automakers' organizations co-evolved with regulations specifying who was at fault in vehicle impacts, how vehicles should be built to withstand the force of an impact, and how testing should be done to assure that vehicles met those requirements. Changes in the regulatory environment were bolstered by new theories about crash test dynamics and changing technologies with which to test those theories. Thus, as new technological and regulatory innovations co-evolved with innovations in organizational structuring, ideas about how to best conduct crash tests shifted and catalyzed new cycles of technological, regulatory, and organizational innovation. However, this co-evolutionary story tells us that the move from road to lab to math was not natural or linear as today's managerial rhetoric would have us believe. Rather, the logic of math-based simulation was the result of technological, regulatory and organizational changes that created an industry-wide ideology that supported the move toward math while making it appear natural within the shifting structure of the industry.

  19. Investigating load management technology options: a survey of technologies and issues. Final report. [Competitive interrelationships of LM, conservation, and renewables

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-12-01

    Load-management-technology options are commercially available and may be desirable in many utility-service areas. Energy-conservation and renewable-energy-supply technologies are also cost-effective in many applications and, where installed, may reduce the effectiveness and attractiveness of load-management options. Recent energy legislation has not addressed these competitive interrelationships; future legislation is unlikely to do so unless a coordinated task-force effort among relevant DOE offices is pursued to derive strategic technology and policy recommendations on this issue. R and D strategies should help formulate these recommendations.

  20. Two regional regulatory meetings on distributed resources. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2001-02-01

    An overview and discussion of Eastern Regional and Western Regional State Utility Regulators Workshops on Distributed Resources (DR) is given. The purpose of the workshops was for state regulators to learn about DR and the regulatory issues surrounding their greater use. The following issues were addressed: introduction to DR technologies and their potential benefits, interconnection and market barriers, regulatory incentives, rate design issues, and environmental issues.

  1. An Investigation of Information Technology-Enabled Remote Management and Remote Work Issues

    Directory of Open Access Journals (Sweden)

    D. Sandy Staples

    1997-05-01

    Full Text Available A two phase research study was done to investigate remote work and remote management issues. In Phase 1, focus groups were carried out with remote managers and remote employees to identify key issues. The most common key issues dealt with communications, information technology, leadership and coaching, teamwork, building trust, and performance management. In the second phase, a questionnaire was used to test hypotheses developed from phase 1. The findings supported that higher trust leads to higher job satisfaction and lower job stress, and that more communication between the manager and the remote employee develops higher levels of employee organizational commitment.

  2. Creating virtual communities of practice for learning technology in higher education: issues, challenges and experiences

    OpenAIRE

    Jacqueline A. Dempster; Beetham, Helen; Jackson, Peter; Richardson, Steven

    2003-01-01

    The need for a Web portal to support the rapidly growing field of learning technology has been well established through a number of national surveys and scoping studies over recent years. The overarching vision has been the provision of a virtual environment to assist in informing and developing professional practice in the use of learning technologies. This paper outlines the issues and challenges in creating such a portal through the experiences of developing the RESULTs Network. In the pap...

  3. Address for the Beginning Issue of “RFID Technologies and Applicationsn”

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Recently RFID technology got a widely attentions. As a result of this, RFID Technology and Application is published as the first professional RFID publication mainly issuing in the China and Hong Kong, Macao and Taiwan. This article summarizes the RFID characteristic, suitable applied field and its development situation and its developing reason in Asia-Pacific area. The article also presents the Magazine’s target and goal, column and the future perspective.

  4. POLICY ANALYSIS OF PRODUCED WATER ISSUES ASSOCIATED WITH IN-SITU THERMAL TECHNOLOGIES

    Energy Technology Data Exchange (ETDEWEB)

    Robert Keiter; John Ruple; Heather Tanana

    2011-02-01

    Commercial scale oil shale and oil sands development will require water, the amount of which will depend on the technologies adopted and the scale of development that occurs. Water in oil shale and oil sands country is already in scarce supply, and because of the arid nature of the region and limitations on water consumption imposed by interstate compacts and the Endangered Species Act, the State of Utah normally does not issue new water rights in oil shale or oil sands rich areas. Prospective oil shale and oil sands developers that do not already hold adequate water rights can acquire water rights from willing sellers, but large and secure water supplies may be difficult and expensive to acquire, driving oil shale and oil sands developers to seek alternative sources of supply. Produced water is one such potential source of supply. When oil and gas are developed, operators often encounter ground water that must be removed and disposed of to facilitate hydrocarbon extraction. Water produced through mineral extraction was traditionally poor in quality and treated as a waste product rather than a valuable resource. However, the increase in produced water volume and the often-higher quality water associated with coalbed methane development have drawn attention to potential uses of produced water and its treatment under appropriations law. This growing interest in produced water has led to litigation and statutory changes that must be understood and evaluated if produced water is to be harnessed in the oil shale and oil sands development process. Conversely, if water is generated as a byproduct of oil shale and oil sands production, consideration must be given to how this water will be disposed of or utilized in the shale oil production process. This report explores the role produced water could play in commercial oil shale and oil sands production, explaining the evolving regulatory framework associated with produced water, Utah water law and produced water regulation

  5. Studying Marriage and Family Therapists in the 21st Century: Methodological and Technological Issues

    Science.gov (United States)

    Northey, William F., Jr.

    2005-01-01

    In this article, I present data from two waves of research on demographic characteristics and practice patterns of marriage and family therapists (MFTs) conducted in 2000 and 2002. The research focuses on the methodological and technological issues in studying this population. Specifically, an online survey with MFTs obtained lower response rates…

  6. Future Critical Issues and Problems Facing Technology and Engineering Education in the Commonwealth of Virginia

    Science.gov (United States)

    Katsioloudis, Petros; Moye, Johnny J.

    2012-01-01

    The purpose of this research was to determine the future critical issues and problems facing the K-12 technology and engineering education profession in the Commonwealth of Virginia. This study was based on the Wicklein nationwide studies (1993a, 2005). Even though this study did not exactly replicate the Wicklein studies--since it was limited to…

  7. Beyond Digital Natives: European Research on Media Education; Challenges of Technology and Pedagogical Issues

    Science.gov (United States)

    Rivoltella, Pier Cesare

    2012-01-01

    This article aims to map issues of Media Education currently under debate in Europe. It points out three main research trends. The first one concerns digital natives and their skills in media and technologies. Here we have quite a dialectic situation: on the one hand, a lot of scholars and policymakers are sure that digital natives exist, that…

  8. Gender issues in US science and technology policy: equality of what?

    Science.gov (United States)

    Cozzens, Susan E

    2008-09-01

    Fairness in evaluation processes for women in science and engineering is only one of a set of issues that need to be addressed to reach gender equality. This article uses concepts from Amartya Sen's work on inequality to frame gender issues in science and technology policy. Programs that focus on increasing the number of women in science and engineering careers have not generally addressed a broader set of circumstances that intersect with gender at various economic levels and stages of life. The agendas in research and innovation policies also need to reflect these issues, and fair allocation of resources within both science and technology needs to be on the agenda. Getting women into high-level positions is not enough. Articulating the full research and innovation agendas for women will require broader participatory processes.

  9. E-Business: Application of software and technology in selected Ethiopian banks - Issues and challenges

    Directory of Open Access Journals (Sweden)

    Bhaskar Reddy Muvva Vijay

    2011-11-01

    Full Text Available The application of software and technology is inevitable in the present competitive banking industry. Ethiopian banking system is one of the most underdeveloped compared to the rest of the world. In Ethiopia cash is still the most dominant medium of exchange and Electronic-banking is not well known, let alone used for transacting banking issues. The article tries to examine specific issues and challenges in Ethiopian banking system. The present study further highlights various selecting issues and service quality systems practiced in selected banks. Survey method is used to collect data from practicing managers of banking industry. It further analyzes the present obstacles and hindrances in improving and facilitating the present banking services with application of customize software and technology.

  10. Regulatory Safety Issues in the Structural Design Criteria of ASME Section III Subsection NH and for Very High Temperatures for VHTR & GEN IV

    Energy Technology Data Exchange (ETDEWEB)

    William J. O’Donnell; Donald S. Griffin

    2007-05-07

    The objective of this task is to identify issues relevant to ASME Section III, Subsection NH [1], and related Code Cases that must be resolved for licensing purposes for VHTGRs (Very High Temperature Gas Reactor concepts such as those of PBMR, Areva, and GA); and to identify the material models, design criteria, and analysis methods that need to be added to the ASME Code to cover the unresolved safety issues. Subsection NH was originally developed to provide structural design criteria and limits for elevated-temperature design of Liquid Metal Fast Breeder Reactor (LMFBR) systems and some gas-cooled systems. The U.S. Nuclear Regulatory Commission (NRC) and its Advisory Committee for Reactor Safeguards (ACRS) reviewed the design limits and procedures in the process of reviewing the Clinch River Breeder Reactor (CRBR) for a construction permit in the late 1970s and early 1980s, and identified issues that needed resolution. In the years since then, the NRC and various contractors have evaluated the applicability of the ASME Code and Code Cases to high-temperature reactor designs such as the VHTGRs, and identified issues that need to be resolved to provide a regulatory basis for licensing. This Report describes: (1) NRC and ACRS safety concerns raised during the licensing process of CRBR , (2) how some of these issues are addressed by the current Subsection NH of the ASME Code; and (3) the material models, design criteria, and analysis methods that need to be added to the ASME Code and Code Cases to cover unresolved regulatory issues for very high temperature service.

  11. Why people use and don't use technologies: Introduction to the special issue on assistive technologies for cognition/cognitive support technologies.

    Science.gov (United States)

    Scherer, Marcia J; Federici, Stefano

    2015-01-01

    This special issue focuses on assistive technologies for cognition/cognitive support technologies as well as the ways in which individuals are assessed and trained in their use. We provide eleven diverse articles that give information on products, why they are used and not used, and best professional practices in service provision. Our goal is to highlight a broad topic that has received limited research investigation and offer an insight into how different countries and programs are promoting access to and use of assistive technologies for cognition/cognitive support technologies.

  12. TRENDS AND ISSUES: A REVIEW OF STUDIES RELATED TO TECHNOLOGY USAGE IN EARLY CHILDHOOD EDUCATION

    Directory of Open Access Journals (Sweden)

    Elif ÖZTÜRK YILMAZTEKİN

    2013-06-01

    Full Text Available This paper describes types of technology studies that have been conducted related to young children’s early education. A systematic review of studies was undertaken using EBSCOhost, Blackwell Synergy, and ScienceDirect databases, to identify all studies published between 2003 and 2009 according to specific criteria. The studies were selected on the basis of the following three issues: (1 the role of technology in children’s development, (2 the role of technology in teachers’ teaching practices, and (3 studies that aimed to investigate the impact of technology usage on not only teacher practices but also young children’s development in school settings. In for each type of study the methodology, types of technology used, purposes and findings and other features including the publication year, and study locations are given in detail.

  13. Scientific Issues Relevant to Setting Regulatory Criteria to Identify Endocrine-Disrupting Substances in the European Union

    Science.gov (United States)

    Slama, Rémy; Bourguignon, Jean-Pierre; Demeneix, Barbara; Ivell, Richard; Panzica, Giancarlo; Kortenkamp, Andreas; Zoeller, R. Thomas

    2016-01-01

    , Kortenkamp A, Zoeller RT. 2016. Scientific issues relevant to setting regulatory criteria to identify endocrine disrupting substances in the European Union. Environ Health Perspect 124:1497–1503; http://dx.doi.org/10.1289/EHP217 PMID:27108591

  14. Issues of Doing Gender and Doing Technology--Music as an Innovative Theme for Technology Education

    Science.gov (United States)

    Thaler, A.; Zorn, I.

    2010-01-01

    This paper presents the concept and results of the research project "Engineer Your Sound!" (2008-2009). It aimed at exploring whether interdisciplinary, innovative teaching/learning settings in the fields of technology and digital media can be used to give pupils the opportunities to experiment and discover their technical potential, skills,…

  15. Global Information Technology Education: Issues and Trends. Series in Global Information Technology Management.

    Science.gov (United States)

    Khosrowpour, Mehdi; Loch, Karen D.

    This book provides insight into how countries around the world currently define their information science (IS) and information technology (IT) masters degree curriculum, and how they are responding to the challenge of internationalization. Global IT programs from both developed and developing countries are presented. Faculty and researchers are…

  16. Proceedings of the Hydrokinetic and Wave Energy Technologies Technical and Environmental Issues Workshop

    Energy Technology Data Exchange (ETDEWEB)

    None

    2006-03-01

    Renewable energy technologies offer the promise of non-polluting alternatives to fossil and nuclear-fueled power plants to meet growing demand for electrical energy. Two emerging categories of renewable energy technologies, hydrokinetic and wave energy conversion devices, offer ways to tap the energy of moving water without impoundment (dams) or diversion required by many conventional hydroelectric facilities. These technologies include devices designed for deployment in natural streams, tidal estuaries, ocean currents, and constructed waterways, as well as devices designed to capture the energy of ocean waves. On October 26-28, 2005, 54 representatives from government, non-governmental organizations, and private business met to (1) identify the varieties of hydrokinetic energy and wave technology devices, their stages of development, and the projected cost to bring each to market; (2) identify where these technologies can best operate; (3) identify the potential environmental issues associated with these technologies and possible mitigation measures; (4) develop a list of research needs and/or practical solutions to address unresolved environmental issues. These workshop proceedings include detailed summaries of the 24 presentations made and the discussions that followed.

  17. Occupational therapy research on assistive technology and physical environmental issues: a literature review.

    Science.gov (United States)

    Ivanoff, Synneve Dahlin; Iwarsson, Susanne; Sonn, Ulla

    2006-04-01

    To determine future directions for research in the area of assistive technology and physical environmental issues, it is important to have an understanding of prior research. This literature review examined how assistive technology and physical environmental issues have been studied in the research published in international peer-reviewed occupational therapy journals. Five recent volumes of nine journals were manually searched utilizing specific criteria. The publications were classified according to their perspective, application of the Person-Environment-Occupation (PEO) model, and the research design. Both research fields demonstrated use of different research methods and they displayed equal needs with regard to improved research methodologies. There are a lack of studies involving all three PEO components indicating a lack of research in occupational performance issues. Further research on occupational performance is important for developing occupational therapy practice in the area of assistive technology and physical environmental issues. Furthermore, study designs reflecting the societal level in all three PEO components are required. Finally, there is a strong need for conceptual and theoretical development in both fields.

  18. Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

    Directory of Open Access Journals (Sweden)

    Miles Parker

    Full Text Available Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security.

  19. Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

    Science.gov (United States)

    Parker, Miles; Acland, Andrew; Armstrong, Harry J; Bellingham, Jim R; Bland, Jessica; Bodmer, Helen C; Burall, Simon; Castell, Sarah; Chilvers, Jason; Cleevely, David D; Cope, David; Costanzo, Lucia; Dolan, James A; Doubleday, Robert; Feng, Wai Yi; Godfray, H Charles J; Good, David A; Grant, Jonathan; Green, Nick; Groen, Arnoud J; Guilliams, Tim T; Gupta, Sunjai; Hall, Amanda C; Heathfield, Adam; Hotopp, Ulrike; Kass, Gary; Leeder, Tim; Lickorish, Fiona A; Lueshi, Leila M; Magee, Chris; Mata, Tiago; McBride, Tony; McCarthy, Natasha; Mercer, Alan; Neilson, Ross; Ouchikh, Jackie; Oughton, Edward J; Oxenham, David; Pallett, Helen; Palmer, James; Patmore, Jeff; Petts, Judith; Pinkerton, Jan; Ploszek, Richard; Pratt, Alan; Rocks, Sophie A; Stansfield, Neil; Surkovic, Elizabeth; Tyler, Christopher P; Watkinson, Andrew R; Wentworth, Jonny; Willis, Rebecca; Wollner, Patrick K A; Worts, Kim; Sutherland, William J

    2014-01-01

    Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics) elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security.

  20. Animal testing, 3R models and regulatory acceptance : Technology transition in a risk-averse context

    NARCIS (Netherlands)

    Schiffelers, M.J.W.A.|info:eu-repo/dai/nl/294583416

    2016-01-01

    Risk avoidance has resulted in a broad range of regulations to guarantee the safety of products such as pharmaceuticals and chemicals. Many of these regulations rely on animal tests. About 3 million laboratory animals are used annually in Europe to meet such regulatory requirements.Regulatory animal

  1. Animal testing, 3R models and regulatory acceptance : Technology transition in a risk-averse context

    NARCIS (Netherlands)

    Schiffelers, M.J.W.A.

    2016-01-01

    Risk avoidance has resulted in a broad range of regulations to guarantee the safety of products such as pharmaceuticals and chemicals. Many of these regulations rely on animal tests. About 3 million laboratory animals are used annually in Europe to meet such regulatory requirements.Regulatory animal

  2. [Social consensus on medical technology policy: ethical issues and citizen participation].

    Science.gov (United States)

    Sato, Hajime

    2004-01-01

    Social consensus is considered to be a necessary condition for a policy to be introduced and implemented effectively. This is the case with the approval, regulation and prohibition of certain advanced medical research and technology, especially when they could invoke moral disputes in society. Public policies on organ transplantation, definition of death, euthanasia, genetic screening and diagnosis, and human stem cell research are recent examples. The concept of consensus, however, is elusive, along with the measures to secure it. Technocratic decision making, as a paternalistic activity frequently led by experts, sometimes poses a challenge to democratic decision making, supposedly based on a well-informed and rational public. It also remains to be proved whether public involvement in policymaking can be a solution to ethical value conflicts in society. From the perspective of policy sciences, this paper first introduces the concept of consensus, especially consensus on moral issues in pluralistic societies, and its implications to public policy, including citizen participation in decision making. Then, it briefly explains the historical background with which social consensus and public involvement have increasingly flourished in the field of technology assessments and technology policy making, including biomedical technology. Next, major institutions, governmental and nongovernmental, involved in the ethical aspects of medical research and technology, are presented along with their efforts for citizen participation. Finally, the paper discusses some of the future agendas on this issue.

  3. Coal gasification systems engineering and analysis. Appendix F: Critical technology items/issues

    Science.gov (United States)

    1980-01-01

    Critical technology items and issues are defined in which there is a need for developmental research in order to assure technical and economic success for the state of the art of coal gasification in the United States. Technology development needs for the main processing units and the supporting units are discussed. While development needs are shown for a large number of systems, the most critical areas are associated with the gasifier itself and those systems which either feed the gasifier or directly receive products form the gasifier.

  4. Critical issues in medical education and the implications for telemedicine technology.

    Science.gov (United States)

    Mahapatra, Ashok Kumar; Mishra, Saroj Kanta; Kapoor, Lily; Singh, Indra Pratap

    2009-01-01

    Ensuring quality medical education in all the medical colleges across India based on uniform curriculum prescribed by a regulatory body and maintaining a uniform standard are dependent on availability of an excellent infrastructure. Such infrastructure includes qualified teachers, knowledge resources, learning materials, and advanced education technology, which is a challenge in developing countries due to financial and logistic constraints. Advancement in telecommunication, information science, and technology provides an opportunity to exchange knowledge and skill across geographically dispersed organizations by networking academic medical centers of excellence with medical colleges and institutes to practice distance learning using information and communication technology (ICT)-based tools. These may be as basic as commonly used Web-based tools or may be as advanced as virtual reality, simulation, and telepresence-based collaborative learning environment. The scenario in India is no different from any developing country, but there is considerable progress due to technical advancement in these sectors. Telemedicine and tele-education in health science, is gradually getting adopted into the Indian Health System after decade-long pilot studies across the country. A recent recommendation of the National Knowledge Commission, once implemented, would ensure a gigabyte network across all the educational institutions of the country including medical colleges. Availability of indigenous satellite communication technology and the government policy of free bandwidth provision for societal development sector have added strength to set up infrastructure to pilot several telemedicine educational projects across the country.

  5. Technological Issues and High Gradient Test Results on X-Band Molybdenum Accelerating Structures

    Energy Technology Data Exchange (ETDEWEB)

    Spataro, B.; /LNF, Dafne Light; Alesini, D.; /LNF, Dafne Light; Chimenti, V.; /LNF, Dafne Light; Dolgashev, V.; /SLAC; Haase, A.; /SLAC; Tantawi, S.G.; /SLAC; Higashi, Y.; /KEK, Tsukuba; Marrelli, C.; /Rome U.; Mostacci, A.; /Rome U.; Parodi, R.; /INFN, Genoa; Yeremian, A.D.; /SLAC

    2012-04-24

    Two 11.424 GHz single cell standing wave accelerating structures have been fabricated for high gradient RF breakdown studies. Both are brazed structures: one made from copper and the other from sintered molybdenum bulk. The tests results are presented and compared to those of similar devices constructed at SLAC (Stanford Linear Accelerator Center) and KEK (Ko Enerugi Kasokuki Kenkyu Kiko). The technological issues to build both sections are discussed.

  6. Technological issues and high gradient test results on X-band molybdenum accelerating structures

    Energy Technology Data Exchange (ETDEWEB)

    Spataro, B., E-mail: bruno.spataro@lnf.infn.it [INFN-LNF, Via E. Fermi 40, 00044 Frascati (Italy); Alesini, D.; Chimenti, V. [INFN-LNF, Via E. Fermi 40, 00044 Frascati (Italy); Dolgashev, V.; Haase, A.; Tantawi, S.G. [SLAC, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States); Higashi, Y. [KEK 1-1 Oho, Tsukuba, Ibaraki, 305-0801 (Japan); Marrelli, C.; Mostacci, A. [University of Rome Sapienza, Department of Fundamental and Applied Science for Engineering, Via A. Scarpa 14, 00185 Rome (Italy); Parodi, R. [INFN-Genova, Via Dodecaneso 33, 16146 Genova (Italy); Yeremian, A.D. [SLAC, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States)

    2011-11-21

    Two 11.424 GHz single cell standing wave accelerating structures have been fabricated for high gradient RF breakdown studies. Both are brazed structures: one made from copper and the other from sintered molybdenum bulk. The tests results are presented and compared to those of similar devices constructed at SLAC (Stanford Linear Accelerator Center) and KEK (Ko Enerugi Kasokuki Kenkyu Kiko). The technological issues to build both sections are discussed.

  7. Proceedings of the tenth annual DOE low-level waste management conference: Session 1: Institutional and regulatory issues

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-01

    This document contains eleven papers on various aspects of low-level radioactive waste regulation. Topics include: EPA environmental standards; international exemption principles; the concept of below regulatory concern; envirocare activities in Utah; mixed waste; FUSRAP and the Superfund; and a review of various incentive programs. Individual papers are processed separately for the data base. (TEM)

  8. Creating virtual communities of practice for learning technology in higher education: issues, challenges and experiences

    Directory of Open Access Journals (Sweden)

    Jacqueline A. Dempster

    2003-12-01

    Full Text Available The need for a Web portal to support the rapidly growing field of learning technology has been well established through a number of national surveys and scoping studies over recent years. The overarching vision has been the provision of a virtual environment to assist in informing and developing professional practice in the use of learning technologies. This paper outlines the issues and challenges in creating such a portal through the experiences of developing the RESULTs Network. In the paper, design and participation issues are considered within the wider context of online and networked approaches to supporting practice and professional development. User participation methodologies and technical developments for RESULTs are described in relation to a review of existing representations of practice and a comprehensive survey amongst the learning technology users' community. An outline of key achievements and experiences is presented, followed by some conclusions regarding the cultural and political issues in creating a viable and sustainable facility and suggestions for possible future direction in national provision.

  9. Impact of STS Issue Oriented Instruction on Pre-Service Elementary Teachers' Views and Perceptions of Science, Technology, and Society

    Science.gov (United States)

    Amirshokoohi, Aidin

    2016-01-01

    The purpose of the study was to investigate the impact of Science, Technology, Society (STS) issue oriented science methods course on pre-service teachers' views and perceptions toward STS issues and instruction as well as their levels of environmental literacy. The STS issue oriented curriculum was designed to help pre-service teachers improve…

  10. FINESSE: study of the issues, experiments and facilities for fusion nuclear technology research and development. Interim report. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.

    1984-10-01

    The Nuclear Fusion Issues chapter contains a comprehensive list of engineering issues for fusion reactor nuclear components. The list explicitly defines the uncertainties associated with the engineering option of a fusion reactor and addresses the potential consequences resulting from each issue. The next chapter identifies the fusion nuclear technology testing needs up to the engineering demonstration stage. (MOW)

  11. Localisation of Information and Communication Technologies in Cameroonian Languages and Cultures:Experience and Issues

    Directory of Open Access Journals (Sweden)

    Mathurin Soh

    2015-12-01

    Full Text Available In this paper, we tackle the problem of adapting Information and Communication Technologies (ICTs in local languages of Cameroon. The objectives are to reduce the digital and language divides, and to pave the way for the usage of such technologies to local populations who don’t understand this technological language. We first discuss and highlight several concerns about the localisation of ICTs. Afterwords, we address some challenges and issues to computerize cultural and linguistic features, and indigenous knowledge (IK for national languages and cultures in Cameroon. As case study, we describe our experience in localising an open source editor for the Yemba language, within the of Rural Electronic Schools in African Languages Project. Because Cameroonian languages are based on the same basic alphabet, this qualitative research is extensible to other languages.

  12. Issues in mass spectrometry between bench chemists and regulatory laboratory managers: summary of the roundtable on mass spectrometry held at the 123rd AOAC International Annual Meeting.

    Science.gov (United States)

    Heller, David N; Lehotay, Steven J; Martos, Perry A; Hammack, Walter; Fernández-Alba, Amadeo R

    2010-01-01

    At the 123rd AOAC International Annual Meeting in Philadelphia, PA, 45 residue chemists gathered for a roundtable discussion of mass spectrometry (MS) used for regulatory chemical residues analysis. The session was conceived to address current technical and communication issues about MS between "bench chemists and their bosses". The topics covered a range of practical, routine, and recurring issues on capabilities and limitations of MS techniques, and suggestions on how chemists may better communicate their MS results with customers. The customers in this sense include laboratory managers, quality assurance officers, laboratory clients, regulatory officials, policy-makers, lawyers, and others who have interest in the data. The stated goals devised by the roundtable panelists were to provide independent advice, describe limitations, give practical tips, help set realistic expectations, and answer questions from the attendees. The panelists divided the topics into three main themes: practical aspects in routine analysis using MS, choice of MS technique depending on the purpose for analysis, and qualitative identification and confirmation concepts. This report was written to summarize and expand upon the discussion, frame the current issues, and provide advice on handling common situations in MS analysis and reporting of results. Topics included LODs, data quality objectives, quantification and reporting results, matrix effects, calibration, terminology, differences in performance across MS platforms, proficiency testing, qualitative analysis, and laboratory accreditation. Conclusions are presented as a set of questions for structuring a dialog between bench chemists and laboratory managers.

  13. Research and Development initiative of Satellite Technology Application for Environmental Issues in Asia Region

    Science.gov (United States)

    Hamamoto, K.; Kaneko, Y.; Sobue, S.; Oyoshi, K.

    2016-12-01

    Climate change and human activities are directly or indirectly influence the acceleration of environmental problems and natural hazards such as forest fires, drought and floods in the Asia-Pacific countries. Satellite technology has become one of the key information sources in assessment, monitoring and mitigation of these hazards and related phenomenon. However, there are still gaps between science and application of space technology in practical usage. Asia-Pacific Regional Space Agency Forum (APRSAF) recommended to initiate the Space Applications for Environment (SAFE) proposal providing opportunity to potential user agencies in the Asia Pacific region to develop prototype applications of space technology for number of key issues including forest resources management, coastal monitoring and management, agriculture and food security, water resource management and development user-friendly tools for application of space technology. The main activity of SAFE is SAFE prototyping. SAFE prototyping is a demonstration for end users and decision makers to apply space technology applications for solving environmental issues in Asia-Pacific region. By utilizing space technology and getting technical support by experts, prototype executers can develop the application system, which could support decision making activities. SAFE holds a workshop once a year. In the workshop, new prototypes are approved and the progress of on-going prototypes are confirmed. Every prototype is limited for two years period and all activities are operated by volunteer manner. As of 2016, 20 prototypes are completed and 6 prototypes are on-going. Some of the completed prototypes, for example drought monitoring in Indonesia were applied to operational use by a local official organization.

  14. The Regulatory Emotional Self-Efficacy Scale: Issues of Reliability and Validity Within a Turkish Sample Group

    Directory of Open Access Journals (Sweden)

    Tarık Totan

    2014-10-01

    Full Text Available The purpose of this study was to psychometrically evaluate the Turkish version of the Regulatory Emotional Self-efficacy Scale (RESE. The RESE, the Emotional Self-efficacy Scale, the Self-liking/Self-competence Scale, and the Oxford Happiness Questionnaire were applied to 303 university students in total, 180 were women (59.4% and 123 were men (40.6%. According to results of confirmatory factor analysis applied in the study are founded enough conformity between the priori hypothesis model and the data. In addition, the metric invariance model shows that there were no gender differences on this confirmatory model. Internal consistency coefficients were all above the acceptable for the RESE’s sub-scale and total. Moreover, positive correlations were found between regulatory emotional self-efficacy dimensions and emotional self-efficacy, self-esteem, and happiness. According to these research findings, the RESE is a valid and reliable instrument for measuring regulatory self-efficacy in Turkish.

  15. Use Of Renewable Energy In The Electric Power Generation Sector In Mexico: Political, Regulatory, Economic And Technical Issues From 1965 To 2018

    Energy Technology Data Exchange (ETDEWEB)

    Elizalde-Baltierra, Alberto; Sasse, Diana; Zeferino-Abundis, Yolanda; Quiroz-Juarez, Carolina; Lopez-Satow, Edgar; Beltran-Mora, Hector; Crisostomo-Ramirez, David

    2010-09-15

    The aim of this work is to analyze the political, regulatory, economic and technical issues that have determined the use of primary energies for power generation in Mexico from 1965 to 2008, and its perspectives for the next 10 years, in particular the prospects of using renewable energies. In the 60's, hydro was the preferred source of energy to produce electricity for economical and technical reasons. Under the 'oil boom' in the 70s, transition to hydrocarbons resources (fuel oil) was progressive. As a result of implementing environmental policies, electricity has mainly been generated with natural gas since the early 2000.

  16. Evaluation of Policy and Research Interventions in Science and Technology: Consequence Assessment of Regulatory and Technology Transfer Programs

    Science.gov (United States)

    Dias, Mary Beatrice

    2011-01-01

    This research contributes to efforts in assessment studies related to science and technology interventions. The work presented in this thesis focuses on understanding the effects of policies that influence science and technology interventions, and determining the impact of science and technology interventions themselves. Chapter 1 explores how…

  17. A reappraisal of transport aircraft needs 1985 - 2000: Perceptions of airline management in a changing economic, regulatory, and technological environment

    Science.gov (United States)

    Spencer, F. A.

    1982-01-01

    Views of the executives of 24 major, national, regional, and commuter airlines concerning the effect of recent regulatory, economic, and technological changes on the roles they see for their airlines, and consequent changes in their plans for acquiring aircraft for the 1985 to 2000 period were surveyed. Differing perceptions on the economic justification for new-technology jets in the context of the carriers' present and projected financial conditions are outlined. After examining the cases for new or intermediate size jets, the study discusses turboprop powered transports, including the carriers' potential interest in an advanced technology, high-speed turboprop or prop-fan. Finally, the implications of foreign competition are examined in terms of each carrier's evaluation of the quality and financial offerings, as well as possible 'Buy American' policy predisposition.

  18. Interactions between the stratum corneum and topically applied products: regulatory, instrumental and formulation issues with focus on moisturizers.

    Science.gov (United States)

    Lodén, M

    2014-09-01

    Virtually everyone in Europe will use at least one cosmetic product every day. The extensive use of cosmetics and results from measurements of quality of life in patients with skin diseases demonstrate the importance of a healthy skin. The skin is not only a barrier against desiccation and intrusion of harmful materials, but also an organ of social communication, where dry, scaly, rough stratum corneum is unappealing to touch, inducing anxiety and depression. Knowledge about the skin biochemistry and the use of noninvasive instruments facilitate the development of topical products and quantification of their effects. The presentation of the products and mode of action determine the regulatory demands and the approval process, as they can fall into different regulatory entities, such as cosmetics, medicinal products, medical devices and as other chemical products. The majority of the topical products on the market are regulated as cosmetics. For example, facial skin care and daily moisturizing routines are frequently used. However, despite visible relief of dryness symptoms, some products are reported to result in deterioration of the skin barrier function. New clinical outcomes show important clinical differences between formulations and the relapse of eczema. In a worst case scenario, treatment with a moisturizing cream may increase the risks of eczema and asthma. In the present overview, product presentations and mode of actions are reflected against the regulatory demands in Europe. The regulations are continuously revisited and new guidelines are being implemented, such as the new cosmetic regulation with advice on testing and responsible marketing. © 2014 The Author BJD © 2014 British Association of Dermatologists.

  19. Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

    NARCIS (Netherlands)

    Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M.; Hekkert, M.P.; Schellekens, H.

    2011-01-01

    The replacement of in vivo methods by in vitro methods in regulatory drug testing is rare. The aim of this research is to identify barriers and drivers of the replacement of in vivo methods by in vitro methods in Europe. We studied two cases. The first case is the Draize eye test. Since 2009, the in

  20. Implementation of in vitro replacement technologies in regulatory drug testing - An innovation systems perspective

    NARCIS (Netherlands)

    Kooijman, M.; Van Meer, P.J.K.; Moors, E.H.M.; Hekkert, M.P.; Schellekens, H.

    2011-01-01

    The replacement of in vivo methods by in vitro methods in regulatory drug testing is rare. The aim of this research is to identify barriers and drivers of the replacement of in vivo methods by in vitro methods in Europe. We studied two cases. The first case is the Draize eye test. Since 2009, the in

  1. Extraction of human factors issues caused by application of the advanced HSI technology and development of human factor issue management system

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Sang Moon; Lee, Jung Woon; Park, Jae Chang; Oh, In Seok [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-01-01

    A comprehensive literature survey was performed in this study to collect human performance issues related to the advanced HSI design features. The literature from not only nuclear industry but also other industries was collected and reviewed. The issues were categorized into the following advanced HSI design features: devices characteristics, levels of automation, information design and management, display management, computerized controls, alarm systems, computerized procedures, staffing and crew coordination, and operator support systems. The classified issues were described with the description framework. Then, the relationship of issues to HSI design process such as human factors analyses, human factors design, and human factors verification and validation was investigated. Finally, the issue management system of server-client environment was developed using Microsoft's Active Server Page technology and Access 97. (author). 18 refs., 6 figs.

  2. Understandings of the nature of science and decision making on science and technology-based issues

    Science.gov (United States)

    Bell, Randy Lee

    Current reforms emphasize the development of scientific literacy as the principal goal of science education. The nature of science is considered a critical component of scientific literacy and is assumed to be an important factor in decision making on science and technology based issues. However, little research exists that delineates the role of the nature of science in decision making. The purpose of this investigation was to explicate the role of the nature of science in decision making on science and technology based issues and to delineate the reasoning and factors associated with these types of decisions. The 15-item, open-ended "Decision Making Questionnaire" (DMQ) based on four different scenarios concerning science and technology issues was developed to assess decision making. Twenty-one volunteer participants purposively selected from the faculty of geographically diverse universities completed the questionnaire and follow-up interviews. Participants were subsequently grouped according to their understandings of the nature of science, based on responses to a second open-ended questionnaire and follow-up interview. Profiles of each group's decision making were constructed, based on their previous responses to the DMQ and follow-up interviews. Finally, the two groups' decisions, decision making factors, and decision making strategies were compared. No differences were found between the decisions of the two groups, despite their disparate views of the nature of science. While their reasoning did not follow formal lines of argumentation, several influencing factors and general reasoning patterns were identified. Participants in both groups based their decisions primarily on personal values, morals/ethics, and social concerns. While all participants said they considered scientific evidence in their decision making, most did not require absolute "proof," even though Group B participants held more absolute conceptions of the nature of science. Overall, the

  3. Beyond the techno-thriller: Michael Crichton and societal issues in science and technology

    OpenAIRE

    Stengler, E.

    2015-01-01

    Michael Crichton is primarily known for being an outstanding writer of techno-thrillers and co-creator of the genre. In this paper I suggest that his fictional works can and should be considered under the deeper and wider perspective of his concern for societal issues regarding science and technology with a profound consideration of their effects and on the life of people and the development of society.\\ud \\ud In fact this defining feature of his work is inclusive of numerous works by Michael...

  4. Secure messaging via the cloud and mobile devices: data security issues emerge with new technologies.

    Science.gov (United States)

    Prestigiacomo, Jennifer

    2011-05-01

    The secure messaging space is alive with new innovations that are moving the industry forward. Key in this space is the push toward moving secure messaging to the cloud and pushing it out to mobile devices. Among the examples are solutions that allow physicians to receive encrypted email on mobile devices, as well as ones that allow doctors to securely text-message each other to coordinate care. However, the security issues around these emerging technologies in this very active space must be further explored.

  5. Regulatory Technology Development Plan Sodium Fast Reactor. Mechanistic Source Term Development

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David S. [Argonne National Lab. (ANL), Argonne, IL (United States); Brunett, Acacia Joann [Argonne National Lab. (ANL), Argonne, IL (United States); Bucknor, Matthew D. [Argonne National Lab. (ANL), Argonne, IL (United States); Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States); Sofu, Tanju [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-02-28

    Construction and operation of a nuclear power installation in the U.S. requires licensing by the U.S. Nuclear Regulatory Commission (NRC). A vital part of this licensing process and integrated safety assessment entails the analysis of a source term (or source terms) that represents the release of radionuclides during normal operation and accident sequences. Historically, nuclear plant source term analyses have utilized deterministic, bounding assessments of the radionuclides released to the environment. Significant advancements in technical capabilities and the knowledge state have enabled the development of more realistic analyses such that a mechanistic source term (MST) assessment is now expected to be a requirement of advanced reactor licensing. This report focuses on the state of development of an MST for a sodium fast reactor (SFR), with the intent of aiding in the process of MST definition by qualitatively identifying and characterizing the major sources and transport processes of radionuclides. Due to common design characteristics among current U.S. SFR vendor designs, a metal-fuel, pool-type SFR has been selected as the reference design for this work, with all phenomenological discussions geared toward this specific reactor configuration. This works also aims to identify the key gaps and uncertainties in the current knowledge state that must be addressed for SFR MST development. It is anticipated that this knowledge state assessment can enable the coordination of technology and analysis tool development discussions such that any knowledge gaps may be addressed. Sources of radionuclides considered in this report include releases originating both in-vessel and ex-vessel, including in-core fuel, primary sodium and cover gas cleanup systems, and spent fuel movement and handling. Transport phenomena affecting various release groups are identified and qualitatively discussed, including fuel pin and primary coolant retention, and behavior in the cover gas and

  6. Biomedical, ethical, and moral issues being forced by advanced medical technologies.

    Science.gov (United States)

    Satava, Richard M

    2003-09-01

    Technology is rampant, exponentially growing beyond the bounds normally comprehensible by the human mind. Many of these technologies are so fundamentally disruptive that they challenge the very practice of science. Discoveries once unimaginable except in science fiction are appearing at such a rapid rate that there is no time to evaluate their moral and ethical implications in a deliberate and measured fashion. Genetic engineering, human cloning, tissue engineering, intelligent robotics, nanotechnology, suspended animation, regeneration, and species prolongation are but a few that will revolutionize what it means to be human and what the ultimate fate of the species may be. Unless these issues are addressed at this time, we shall face the consequences of an uncontrolled and unprepared future.

  7. Three-dimensional display technologies of recent interest: principles, status, and issues [Invited].

    Science.gov (United States)

    Hong, Jisoo; Kim, Youngmin; Choi, Hee-Jin; Hahn, Joonku; Park, Jae-Hyeung; Kim, Hwi; Min, Sung-Wook; Chen, Ni; Lee, Byoungho

    2011-12-01

    Recent trends in three-dimensional (3D) display technologies are very interesting in that both old-fashioned and up-to-date technologies are being actively investigated together. The release of the first commercially successful 3D display product raised new research topics in stereoscopic display. Autostereoscopic display renders a ray field of a 3D image, whereas holography replicates a wave field of it. Many investigations have been conducted on the next candidates for commercial products to resolve existing limitations. Up-to-date see-through 3D display is a concept close to the ultimate goal of presenting seamless virtual images. Although it is still far from practical use, many efforts have been made to resolve issues such as occlusion problems.

  8. Retrofit NO{sub x} controls for utility boilers: a synthesis of technologies, issues, and CAAA ozone attainment legislation: Final report 1993

    Energy Technology Data Exchange (ETDEWEB)

    Eskmazi, D.; Cichanowicz, E.; Kokkinos, A.; Stallings, J.; Offen, G. [Electric Power Research Institute, Palo Alto, CA (United States)

    1993-10-01

    This document brings together a set of summary papers on the status of NO{sub x} control technologies for complying with the requirements of the Clean Air Act Amendments (CAAA) of 1990. The individual papers were prepared in mid 1992 as synthesized information for utilities who were beginning to assess their compliance options and enter discussions with their regulatory agencies. Their purpose is to introduce utility engineers and managers, regulators, and the public to the available NO{sub x} reduction options, and to do so in a manner that allows complete and consistent discussions of their performance and potential impacts. They do this by identifying the technologies; presenting their general development status; noting the expected range of NO{sub x} emissions; showing projected costs for each system; describing the various technology, fuel and boiler design factors that contribute to the large span of these ranges; and indicating power plant impacts that may be experienced when applying these controls. These documents are not detailed technical prescriptions for supporting designs or technology selections. All three technology papers focus on retrofit controls, since this is the NO{sub x} compliance issue of greatest urgency to utilities at this time.

  9. 2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3--LBA, biomarkers and immunogenicity).

    Science.gov (United States)

    Amaravadi, Lakshmi; Song, An; Myler, Heather; Thway, Theingi; Kirshner, Susan; Devanarayan, Viswanath; Ni, Yan G; Garofolo, Fabio; Birnboeck, Herbert; Richards, Susan; Gupta, Shalini; Luo, Linlin; Kingsley, Clare; Salazar-Fontana, Laura; Fraser, Stephanie; Gorovits, Boris; Allinson, John; Barger, Troy; Chilewski, Shannon; Fjording, Marianne Scheel; Haidar, Sam; Islam, Rafiqul; Jaitner, Birgit; Kamerud, John; Katori, Noriko; Krinos-Fiorotti, Corinna; Lanham, David; Ma, Mark; McNally, Jim; Morimoto, Alyssa; Mytych, Daniel; Nogueira da Costa, Andre; Papadimitriou, Apollon; Pillutla, Renuka; Ray, Soma; Safavi, Afshin; Savoie, Natasha; Schaefer, Martin; Shih, Judy; Smeraglia, John; Skelly, Michael F; Spond, Jeffrey; Staack, Roland F; Stouffer, Bruce; Tampal, Nilufer; Torri, Albert; Welink, Jan; Yang, Tong-Yuan; Zoghbi, Jad

    2015-12-01

    The 2015 9th Workshop on Recent Issues in Bioanalysis (9th WRIB) took place in Miami, Florida with participation of 600 professionals from pharmaceutical and biopharmaceutical companies, biotechnology companies, contract research organizations and regulatory agencies worldwide. WRIB was once again a 5 day, week-long event - A Full Immersion Bioanalytical Week - specifically designed to facilitate sharing, reviewing, discussing and agreeing on approaches to address the most current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS and LBA approaches, including the focus on biomarkers and immunogenicity. This 2015 White Paper encompasses recommendations emerging from the extensive discussions held during the workshop, and is aimed to provide the bioanalytical community with key information and practical solutions on topics and issues addressed, in an effort to enable advances in scientific excellence, improved quality and better regulatory compliance. Due to its length, the 2015 edition of this comprehensive White Paper has been divided into three parts. Part 3 discusses the recommendations for large molecule bioanalysis using LBA, biomarkers and immunogenicity. Part 1 (small molecule bioanalysis using LCMS) and Part 2 (hybrid LBA/LCMS and regulatory inputs from major global health authorities) have been published in volume 7, issues 22 and 23 of Bioanalysis, respectively.

  10. Disabling and Enabling Technologies for Learning in Higher Education for All: Issues and Challenges for Whom?

    Directory of Open Access Journals (Sweden)

    Sangeeta Bagga-Gupta

    2016-10-01

    Full Text Available Integration, inclusion, and equity constitute fundamental dimensions of democracy in post-World War II societies and their institutions. The study presented here reports upon the ways in which individuals and institutions both use and account for the roles that technologies, including ICT, play in disabling and enabling access for learning in higher education for all. Technological innovations during the 20th and 21st centuries, including ICT, have been heralded as holding significant promise for revolutionizing issues of access in societal institutions like schools, healthcare services, etc. (at least in the global North. Taking a socially oriented perspective, the study presented in this paper focuses on an ethnographically framed analysis of two datasets that critically explores the role that technologies, including ICT, play in higher education for individuals who are “differently abled” and who constitute a variation on a continuum of capabilities. Functionality as a dimension of everyday life in higher education in the 21st century is explored through the analysis of (i case studies of two “differently abled” students in Sweden and (ii current support services at universities in Sweden. The findings make visible the work that institutions and their members do through analyses of the organization of time and space and the use of technologies in institutional settings against the backdrop of individuals’ accountings and life trajectories. This study also highlights the relevance of multi-scale data analyses for revisiting the ways in which identity positions become framed or understood within higher education.

  11. Sandia technology. Volume 13, number 2 Special issue : verification of arms control treaties.

    Energy Technology Data Exchange (ETDEWEB)

    1989-03-01

    Nuclear deterrence, a cornerstone of US national security policy, has helped prevent global conflict for over 40 years. The DOE and DoD share responsibility for this vital part of national security. The US will continue to rely on nuclear deterrence for the foreseeable future. In the late 1950s, Sandia developed satellite-borne nuclear burst detection systems to support the treaty banning atmospheric nuclear tests. This activity has continued to expand and diversify. When the Non-Proliferation Treaty was ratified in 1970, we began to develop technologies to protect nuclear materials from falling into unauthorized hands. This program grew and now includes systems for monitoring the movement and storage of nuclear materials, detecting tampering, and transmiting sensitive data securely. In the late 1970s, negotiations to further limit underground nuclear testing were being actively pursued. In less than 18 months, we fielded the National Seismic Station, an unattended observatory for in-country monitoring of nuclear tests. In the mid-l980s, arms-control interest shifted to facility monitoring and on-site inspection. Our Technical On-site Inspection Facility is the national test bed for perimeter and portal monitoring technology and the prototype for the inspection portal that was recently installed in the USSR under the Intermediate-Range Nuclear Forces accord. The articles in the special issue of Sundiu Technology describe some of our current contributions to verification technology. This work supports the US policy to seek realistic arms control agreements while maintaining our national security.

  12. Secondary Uses of Personal Identity Information: Policies, Technologies and Regulatory Framework

    DEFF Research Database (Denmark)

    Adjei, Joseph K.; Olesen, Henning

    2012-01-01

    , credential issuers and other stakeholders by addressing core issues relating to secondary use of personal information. The results of a stakeholder workshop in Ghana on secondary use of personal information are presented by stating the core issues and recommendations. We propose the adaptation...

  13. Dissecting regulatory networks in host-pathogen interaction using chIP-on-chip technology.

    Science.gov (United States)

    Sala, Claudia; Grainger, David C; Cole, Stewart T

    2009-05-08

    Understanding host-microbe interactions has been greatly enhanced by our broadening knowledge of the regulatory mechanisms at the heart of pathogenesis. The "transcriptomics" approach of measuring global gene expression has identified genes involved in bacterial pathogenesis. More recently, chromatin immunoprecipitation (ChIP) and hybridization to microarrays (chIP-on-chip) has emerged as a complementary tool that permits protein-DNA interactions to be studied in vivo. Thus, chIP-on-chip can be used to map the binding sites of transcription factors, thereby teasing apart gene regulatory networks. In this Review, we discuss the ChIP-on-chip technique and focus on its application to the study of host-pathogen interactions.

  14. Some spatial aspects of regulatory and technological change in telecommunication industries

    OpenAIRE

    1992-01-01

    This paper makes a contribution to the analysis of regulatory change, an aspect of the broader theoretical debate initiated by the 'regulation school' of economic theorists and others. Unlike much of that debate this paper is focused on an empirical field - telecommunications deregulation -- and on questions of market strategy rather than those purely of production. After an analysis of the nature and rationale for regulation there is a focus upon the political and economic processes leading ...

  15. Regulatory and logistical issues influencing access to antineoplastic and supportive care medications for children with cancer in developing countries.

    Science.gov (United States)

    Wiernikowski, John T; MacLeod, Stuart

    2014-08-01

    Globally there are numerous impediments, both logistical, regulatory and more recently global drug shortages, hindering pediatric access to therapeutic drugs of all types. Efforts to reduce barriers are ongoing and are especially important in low and middle income countries and for children requiring treatment of conditions such as those encountered in pediatric oncology characterized by the risk of life threatening treatment failures. Progress has been made through the efforts of the World Health Organization and regulators in the US and Europe to encourage the development of therapeutic agents for use in pediatrics and measures taken have fostered the availability of stronger pediatric data to guide therapeutic decisions. Nonetheless, pharmaceuticals remain a global commodity, subject to regulation by the World Trade Organization and this has often had detrimental effects in low and middle income countries. This article emphasizes the need for closer international collaboration to address the barriers currently impeding access to antineoplastic and supportive care medicines for children.

  16. 我国电信业监管法律问题探究%China's telecommunications industry regulatory Legal Issues

    Institute of Scientific and Technical Information of China (English)

    郭雯

    2013-01-01

      China’s telecommunications industry regulatory legal system is very scarce, such as the telecommunications industry, in September 2000 introduced the“Telecommunications Regulations”for the separating after breaking monopoly and promoting competition, and create an environment played an important role, but only ordinance can not meet the demand. SP Enterprises remediation process such as opening a ticket can not find a clear basis for regulations; networks duplication, waste of resources not very good twist; integrated sectors and social division of powers long intertwined bad solution. Some of the technical and business integration without legal protection propulsion. Therefore, the study of the telecommunications industry regulatory legal system is very necessary and urgent.%  我国电信行业的监管法律制度非常匮乏,例如电信业,2000年9月出台的《电信条例》,为政企分开后打破垄断、促进竞争、营造环境发挥了重要作用,但仅有条例已不能满足需求。比如SP企业整治过程中开一张罚单找不到一条明确的条规依据;网络重复建设、资源浪费现象得不到很好扭转;与社会综合部门的事权划分长期交织不好解决。一些技术与业务的融合无法律保障推进等。因此,研究电信行业的监管法律制度显得十分必要和迫切。

  17. Defining core issues in utilizing information technology to improve access: evaluation and research agenda.

    Science.gov (United States)

    Jackson, George L; Krein, Sarah L; Alverson, Dale C; Darkins, Adam W; Gunnar, William; Harada, Nancy D; Helfrich, Christian D; Houston, Thomas K; Klobucar, Thomas F; Nazi, Kim M; Poropatich, Ronald K; Ralston, James D; Bosworth, Hayden B

    2011-11-01

    The Department of Veterans Affairs (VA) has been at the vanguard of information technology (IT) and use of comprehensive electronic health records. Despite the widespread use of health IT in the VA, there are still a variety of key questions that need to be answered in order to maximize the utility of IT to improve patient access to quality services. This paper summarizes the potential of IT to enhance healthcare access, key gaps in current evidence linking IT and access, and methodologic challenges for related research. We also highlight four key issues to be addressed when implementing and evaluating the impact of IT interventions on improving access to quality care: 1) Understanding broader needs/perceptions of the Veteran population and their caregivers regarding use of IT to access healthcare services and related information. 2) Understanding individual provider/clinician needs/perceptions regarding use of IT for patient access to healthcare. 3) System/Organizational issues within the VA and other organizations related to the use of IT to improve access. 4) IT integration and information flow with non-VA entities. While the VA is used as an example, the issues are salient for healthcare systems that are beginning to take advantage of IT solutions.

  18. The regulatory environment past and future--incentive or impediment to developments in food science and technology: a perspective from FDA.

    Science.gov (United States)

    Shank, F R; Carson, K

    1994-01-01

    The best system for protecting public health is one that involves two layers of control before food reaches the consumer. The first layer of control is the industry's clear responsibility to prepare food that is safe. The second layer of control is the monitoring that is provided by government to ensure that the industry is doing its job and is in fact producing safe food. While some may view this "second layer" as an impediment in the development and marketing of new technologies, there is another way to look at the "regulatory environment". The regulatory environment itself, is not an impediment to the development of food science and technology. The regulatory environment, with all its components--scientists, consumers, industry, and Congress--defines "safety" within the context of today's technology, scientific capability, and tolerance level of the lay public. The entire regulatory environment serves to guide the development of food science and technology by providing signposts, in the form of scientifically sound regulatory decisions. The scientific basis of these decisions becomes building blocks on which to rest further refinement of the technology, product, ingredient, or packaging material or on which research in related technologies or research in innovative directions can build. This scientific groundwork becomes very important as more and more companies move away from having self-contained research laboratories toward using commercial laboratories and academic institutions, as well as participating in cooperative research endeavors to meet food safety and product development research needs.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. Technical support for the Ohio Clean Coal Technology Program. Volume 2, Baseline of knowledge concerning process modification opportunities, research needs, by-product market potential, and regulatory requirements: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Olfenbuttel, R.; Clark, S.; Helper, E.; Hinchee, R.; Kuntz, C.; Means, J.; Oxley, J.; Paisley, M.; Rogers, C.; Sheppard, W.; Smolak, L. [Battelle, Columbus, OH (United States)

    1989-08-28

    This report was prepared for the Ohio Coal Development Office (OCDO) under Grant Agreement No. CDO/R-88-LR1 and comprises two volumes. Volume 1 presents data on the chemical, physical, and leaching characteristics of by-products from a wide variety of clean coal combustion processes. Volume 2 consists of a discussion of (a) process modification waste minimization opportunities and stabilization considerations; (b) research and development needs and issues relating to clean coal combustion technologies and by-products; (c) the market potential for reusing or recycling by-product materials; and (d) regulatory considerations relating to by-product disposal or reuse.

  20. The ethical, legal, and social issues impacted by modern assisted reproductive technologies.

    Science.gov (United States)

    Brezina, Paul R; Zhao, Yulian

    2012-01-01

    Background. While assisted reproductive technology (ART), including in vitro fertilization has given hope to millions of couples suffering from infertility, it has also introduced countless ethical, legal, and social challenges. The objective of this paper is to identify the aspects of ART that are most relevant to present-day society and discuss the multiple ethical, legal, and social challenges inherent to this technology. Scope of Review. This paper evaluates some of the most visible and challenging topics in the field of ART and outlines the ethical, legal, and social challenges they introduce. Major Conclusions. ART has resulted in a tectonic shift in the way physicians and the general population perceive infertility and ethics. In the coming years, advancing technology is likely to exacerbate ethical, legal, and social concerns associated with ART. ART is directly challenging society to reevaluate the way in which human life, social justice and equality, and claims to genetic offspring are viewed. Furthermore, these issues will force legal systems to modify existing laws to accommodate the unique challenges created by ART. Society has a responsibility to ensure that the advances achieved through ART are implemented in a socially responsible manner.

  1. Process systems engineering issues and applications towards reducing carbon dioxide emissions through conversion technologies

    DEFF Research Database (Denmark)

    Roh, Kosan; Frauzem, Rebecca; Gani, Rafiqul

    2016-01-01

    This paper reviews issues and applications for design of sustainable carbon dioxide conversion processes, specifically through chemical conversion, and the integration of the conversion processes with other systems from a process systems engineering (PSE) view-point. Systematic and computer......-aided methods and tools for reaction network generation, processing route generation, process design/optimization, and sustainability analysis are reviewed with respect to carbon dioxide conversion. Also, the relevant gaps and opportunities are highlighted. In addition, the integration of carbon dioxide...... conversion processes with other systems including coexisting infrastructure and carbon dioxide sources is described.Then, the importance of PSE based studies for such application is discussed. Finally, some perspectives on the status and future directions of carbon dioxide conversion technology...

  2. Issues and Considerations regarding Sharable Data Sets for Recommender Systems in Technology Enhanced Learning

    DEFF Research Database (Denmark)

    Drachsler, Hendrik; Bogers, Toine; Vuorikari, Riina

    2010-01-01

    This paper raises the issue of missing standardised data sets for recommender systems in Technology Enhanced Learning (TEL) that can be used as benchmarks to compare different recommendation approaches. It discusses how suitable data sets could be created according to some initial suggestions......, and investigates a number of steps that may be followed in order to develop reference data sets that will be adopted and reused within a scientific community. In addition, policies are discussed that are needed to enhance sharing of data sets by taking into account legal protection rights. Finally, an initial...... elaboration of a representation and exchange format for sharable TEL data sets is carried out. The paper concludes with future research needs....

  3. Who reaps the benefits, who bears the risks? Comparative optimism, comparative utility, and regulatory preferences for mobile phone technology.

    Science.gov (United States)

    White, Mathew P; Eiser, J Richard; Harris, Peter R; Pahl, Sabine

    2007-06-01

    Although the issue of risk target (e.g., self, others, children) is widely acknowledged in risk perception research, its importance appears underappreciated. To date, most research has been satisfied with demonstrating comparative optimism, i.e., lower perceived risk for the self than others, and exploring its moderators, such as perceived controllability and personal exposure. Much less research has investigated how the issue of target may affect benefit perceptions or key outcomes such as stated preferences for hazard regulation. The current research investigated these issues using data from a public survey of attitudes toward mobile phone technology (N= 1,320). First, results demonstrated comparative optimism for this hazard, and also found moderating effects of both controllability and personal exposure. Second, there was evidence of comparative utility, i.e., users believed that the benefits from mobile phone technology are greater for the self than others. Third, and most important for policy, preferences for handset regulation were best predicted by perceptions of the risks to others but perceived benefits for the self. Results suggest a closer awareness of target can improve prediction of stated preferences for hazard regulation and that it would be profitable for future research to pay more attention to the issue of target for both risk and benefit perceptions.

  4. Toward Successful Implementation of Speech Recognition Technology: A Survey of SRT Utilization Issues in Healthcare Settings.

    Science.gov (United States)

    Clarke, Martina A; King, Joshua L; Kim, Min Soon

    2015-07-01

    To evaluate physician utilization of speech recognition technology (SRT) for medical documentation in two hospitals. A quantitative survey was used to collect data in the areas of practice, electronic equipment used for documentation, documentation created after providing care, and overall thoughts about and satisfaction with the SRT. The survey sample was from one rural and one urban facility in central Missouri. In addition, qualitative interviews were conducted with a chief medical officer and a physician champion regarding implementation issues, training, choice of SRT, and outcomes from their perspective. Seventy-one (60%) of the anticipated 125 surveys were returned. A total of 16 (23%) participants were practicing in internal medicine and 9 (13%) were practicing in family medicine. Fifty-six (79%) participants used a desktop and 14 (20%) used a laptop (2%) computer. SRT products from Nuance were the dominant SRT used by 59 participants (83%). Windows operating systems (Microsoft, Redmond, WA) was used by more than 58 (82%) of the survey respondents. With regard to user experience, 42 (59%) participants experienced spelling and grammatical errors, 15 (21%) encountered clinical inaccuracy, 9 (13%) experienced word substitution, and 4 (6%) experienced misleading medical information. This study shows critical issues of inconsistency, unreliability, and dissatisfaction in the functionality and usability of SRT. This merits further attention to improve the functionality and usability of SRT for better adoption within varying healthcare settings.

  5. Next-generation biofuels: Survey of emerging technologies and sustainability issues.

    Science.gov (United States)

    Zinoviev, Sergey; Müller-Langer, Franziska; Das, Piyali; Bertero, Nicolás; Fornasiero, Paolo; Kaltschmitt, Martin; Centi, Gabriele; Miertus, Stanislav

    2010-10-25

    Next-generation biofuels, such as cellulosic bioethanol, biomethane from waste, synthetic biofuels obtained via gasification of biomass, biohydrogen, and others, are currently at the center of the attention of technologists and policy makers in search of the more sustainable biofuel of tomorrow. To set realistic targets for future biofuel options, it is important to assess their sustainability according to technical, economical, and environmental measures. With this aim, the review presents a comprehensive overview of the chemistry basis and of the technology related aspects of next generation biofuel production, as well as it addresses related economic issues and environmental implications. Opportunities and limits are discussed in terms of technical applicability of existing and emerging technology options to bio-waste feedstock, and further development forecasts are made based on the existing social-economic and market situation, feedstock potentials, and other global aspects. As the latter ones are concerned, the emphasis is placed on the opportunities and challenges of developing countries in adoption of this new industry.

  6. EDITORIAL: Special issue on optical neural engineering: advances in optical stimulation technology Special issue on optical neural engineering: advances in optical stimulation technology

    Science.gov (United States)

    Shoham, Shy; Deisseroth, Karl

    2010-08-01

    a single spine, with two-photon uncaging) and in rapid, flexible spatial-temporal patterns [10-14]. Nevertheless, current technology generally requires damaging doses of UV or violet illumination and the continuous re-introduction of the caged compound, which, despite interest, makes for a difficult transition beyond in vitro preparations. Thus, the tremendous progress in the in vivo application of photo-stimulation tools over the past five years has been largely facilitated by two 'exciting' new photo-stimulation technologies: photo-biological stimulation of a rapidly increasing arsenal of light-sensitive ion channels and pumps ('optogenetic' probes[15-18]) and direct photo-thermal stimulation of neural tissue with an IR laser [19-21]. The Journal of Neural Engineering has dedicated a special section in this issue to highlight advances in optical stimulation technology, which includes original peer-reviewed contributions dealing with the design of modern optical systems for spatial-temporal control of optical excitation patterns and with the biophysics of neural-thermal interaction mediated by electromagnetic waves. The paper by Nikolenko, Peterka and Yuste [22] presents a compact design of a microscope-photo-stimulator based on a transmissive phase-modulating spatial-light modulator (SLM). Computer-generated holographic photo-stimulation using SLMs [12-14, 23] allows the efficient parallel projection of intense sparse patterns of light, and the welcome development of compact, user-friendly systems will likely reduce the barrier to its widespread adoption. The paper by Losavio et al [24] presents the design and functional characteristics of their acousto-optical deflector (AOD) systems for studying spatial-temporal dendritic integration in single neurons in vitro. Both single-photon (UV) and two-photon (femtosecond pulsed IR) AOD uncaging systems are described in detail. The paper presents an excellent overview of the current state of the art and limitations of

  7. A review on technologies and their usage in solid waste monitoring and management systems: Issues and challenges.

    Science.gov (United States)

    Hannan, M A; Abdulla Al Mamun, Md; Hussain, Aini; Basri, Hassan; Begum, R A

    2015-09-01

    In the backdrop of prompt advancement, information and communication technology (ICT) has become an inevitable part to plan and design of modern solid waste management (SWM) systems. This study presents a critical review of the existing ICTs and their usage in SWM systems to unfold the issues and challenges towards using integrated technologies based system. To plan, monitor, collect and manage solid waste, the ICTs are divided into four categories such as spatial technologies, identification technologies, data acquisition technologies and data communication technologies. The ICT based SWM systems classified in this paper are based on the first three technologies while the forth one is employed by almost every systems. This review may guide the reader about the basics of available ICTs and their application in SWM to facilitate the search for planning and design of a sustainable new system.

  8. Nanotechnology: legal and ethical issues

    Directory of Open Access Journals (Sweden)

    Baran Agnieszka

    2016-03-01

    Full Text Available Nanotechnology is a very vast field which includes a range of technologies at the nano scale, such as pharmaceuticals, biotechnology, genomics, neuroscience, robotics and information technologies. Nanotechnology is the latest technological innovation in global debates on risk regulation and international cooperation. Regulatory bodies have started dealing with the potential risks posed by nanoparticles. Since 2004 the UE has been developing a regulatory policy to tighten control and to improve regulatory adequacy and knowledge of nanotechnology risks. Currently, specific provisions on nanomaterials have been introduced for biocides, cosmetics, food additives, food labelling and materials in contact with foodstuff. The statement that nanotechnologies do inevitably imply ethical questions. The main problems are public trust, potential risks, issues of environmental impact, transparency of information, responsible nanosciences and nanotechnologies research. The aim of this article is to analysis the main problems regulating nanotechnology and some aspects of ethics.

  9. Implications of Danish Regulatory Policies for Technologies Supporting Sustainable Energy Development

    DEFF Research Database (Denmark)

    Meyer, Niels I

    1997-01-01

    The goal of the official Danish energy plans is to establish a sustainable energy development.This goal has been promoted by government programmes and regulations in different ways. Thus, the government has established test stations to secure a high quality of the new technologies and to certify ...... of the electricity market is raising serious questions for a sustainable development. The above points are discussed in the paper....

  10. EMERGING I&C TECHNOLOGIES UNDER THE SHIFTING REGULATORY ENVIRONMENT IN SOUTH KOREA

    Directory of Open Access Journals (Sweden)

    Gyunyoung eHeo

    2015-04-01

    Full Text Available The role of Probabilistic Safety Assessment (PSA has been supplementary and Risk-Informed Applications (RIAs based on the insight from PSA has also been utilized limitedly in the licensing process for Nuclear Power Plants (NPPs in South Korea. However, as the technical significance of PSA is getting increased, PSA has become a mandatory part of Safety Analysis Reports and Periodic Safety Review. It is worthwhile to highlight the role of emerging Instrumentation and Control (I&C technologies including human-machine interface (HMI in developing more credible and realistic PSA models. Particularly, it is expected that the information technology (i.e. software embedded in digital I&C can adjust over- and under conservatism in analyzing risk. In this study, authors proposed the cases which would be able to significantly reduce risk if advanced I&C supported by information technologies is applied. In regard, the several enabling techniques and their effects are proposed. In order to improve the commercial competitiveness of NPPs, the need of collaboration and synergetic outcome of I&C, HMI and PSA should be emphasized.

  11. Young men's health promotion and new information communication technologies: illuminating the issues and research agendas.

    Science.gov (United States)

    Robinson, Mark; Robertson, Steve

    2010-09-01

    The article examines the use of newer, interactive information and communication technologies (ICTs) in young men's health promotion (HP), drawing on gender theory, HP research and evidence on young men's Internet usage. The focus is on highlighting an agenda for research in terms of emerging issues. New forms of social media ICT (for example 'web 2'-based on-line social networking sites, micro-blogging services, i-phones and podcasts) have the potential to enable young men to engage with health information in new and interesting ways. Given concerns about young men's engagement with health services, innovative ICT formats, particularly using the Internet, have been tried. However, issues persist around surfing 'addiction', quality control and equal access. Approaches to HP using new ICTs offer distributed control over information content and quality and a lay social context for accessing information. Online communities can potentially legitimize young men's participation in discourses around health, and support sustained engagement. The article discusses how this could support young men to re-conceptualize healthy choices in the context of masculine imperatives and responsible citizenship if specific conditions are met (for trusting engagement) and risks addressed (such as commercial disinformation). The skill requirements for young men to engage effectively with new ICTs are explored, focusing on health literacy (HL). It is predicted that social marketing approaches to HP for young men will increasingly include new ICTs, making specific requirements for HL. These approaches may appeal narrowly to hegemonic masculinities or broadly to multiple masculinities, including those historically marginalized. Recommendations are made for future research.

  12. Building Irish families through surrogacy: medical and judicial issues for the advanced reproductive technologies.

    LENUS (Irish Health Repository)

    Sills, Eric Scott

    2008-01-01

    Surrogacy involves one woman (surrogate mother) carrying a child for another person\\/s (commissioning person\\/couple), based on a mutual agreement requiring the child to be handed over to the commissioning person\\/couple following birth. Reasons for seeking surrogacy include situations where a woman has non-functional or absent reproductive organs, or as a remedy for recurrent pregnancy loss. Additionally, surrogacy may find application in any medical context where pregnancy is contraindicated, or where a couple consisting of two males seek to become parents through oocyte donation. Gestational surrogacy is one of the main issues at the forefront of bioethics and the advanced reproductive technologies, representing an important challenge to medical law. This analysis reviews the history of surrogacy and clinical and legal issues pertaining to this branch of reproductive medicine. Interestingly, the Medical Council of Ireland does not acknowledge surrogacy in its current practice guidelines, nor is there specific legislation addressing surrogacy in Ireland at present. We therefore have developed a contract-based model for surrogacy in which, courts in Ireland may consider when confronted with a surrogacy dispute, and formulated a system to resolve any potential dispute arising from a surrogacy arrangement. While the 2005 report by the Commission on Assisted Human Reproduction (CAHR) is an expert opinion guiding the Oireachtas\\' development of specific legislation governing assisted human reproduction and surrogacy, our report represents independent scholarship on the contractual elements of surrogacy with particular focus on how Irish courts might decide on surrogacy matters in a modern day Ireland. This joint medico-legal collaborative also reviews the contract for services arrangement between the commissioning person\\/s and the surrogate, and the extent to which the contract may be enforced.

  13. A review on technologies and their usage in solid waste monitoring and management systems: Issues and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Hannan, M.A., E-mail: hannan@eng.ukm.my [Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor DE (Malaysia); Abdulla Al Mamun, Md., E-mail: md.abdulla@siswa.ukm.edu.my [Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor DE (Malaysia); Hussain, Aini, E-mail: aini@eng.ukm.my [Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor DE (Malaysia); Basri, Hassan, E-mail: drhb@ukm.my [Department of Civil and Structural Engineering, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor DE (Malaysia); Begum, R.A., E-mail: rawshan@ukm.edu.my [Institute of Climate Change, Universiti Kebangsaan Malaysia, Bangi, Selangor DE (Malaysia)

    2015-09-15

    Highlights: • Classification of available technologies for SWM system in four core category. • Organization of technology based SWM systems in three main groups. • Summary of SWM systems with target application, methodology and functional domain. • Issues and challenges are highlighted for further design of a sustainable system. - Abstract: In the backdrop of prompt advancement, information and communication technology (ICT) has become an inevitable part to plan and design of modern solid waste management (SWM) systems. This study presents a critical review of the existing ICTs and their usage in SWM systems to unfold the issues and challenges towards using integrated technologies based system. To plan, monitor, collect and manage solid waste, the ICTs are divided into four categories such as spatial technologies, identification technologies, data acquisition technologies and data communication technologies. The ICT based SWM systems classified in this paper are based on the first three technologies while the forth one is employed by almost every systems. This review may guide the reader about the basics of available ICTs and their application in SWM to facilitate the search for planning and design of a sustainable new system.

  14. IEA Wind Task 23 Offshore Wind Technology and Deployment. Subtask 1 Experience with Critical Deployment Issues. Final Technical Report

    OpenAIRE

    Lemming, Jørgen Kjærgaard

    2010-01-01

    The final report for IEA Wind Task 23, Offshore Wind Energy Technology and Deployment, is made up of two separate reports: Subtask 1: Experience with Critical Deployment Issues and Subtask 2: Offshore Code Comparison Collaborative (OC3). The Subtask 1 report included here provides background information and objectives of Task 23. It specifically discusses ecological issues and regulation, electrical system integration and offshore wind, external conditions, and key conclusions for Subtask 1. ...

  15. The Ministry of Industry and Information Technology Issued Detail Breakdown on the Tasks to Eliminate 2009 Backward Production Capacity

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ In order to implement the spirit of "The Announcement from the State Council about Issuing the 2009 Work Plan on Energy-Saving and Emission-Reduction" and the adjustment and revitalization plan for key industries, and further improve the work to eliminate backward production capacity, the Ministry of Industry and Information Technology issued a notice on the detail breakdown and implementation of tasks to eliminate 2009 backward production capacity on November 25, 2009.

  16. The new policy of the trust of the marketing regulatory issues explored%新政策下的信托营销监管问题探究

    Institute of Scientific and Technical Information of China (English)

    刘光波; 龚焕

    2012-01-01

    In the trust company by "products leading" to "customer orientated" tinancial institutions under the guidance of the transformation of idea, banking regulatory commission issued new circular asking trust company construct with customers as the core, professional asset allocation and wealth management as the main service content of the trust of the marketing model. The new marketing mode caused the vibration of the industry, is expected to solve the banking regulatory commission of trust companies and third party company supervision not enough problems. However, the new policy in the marketing personnel qualifications, marketing center of the restrictions, the different marketing center and supervision of three aspects remain loophole; need to further perfect the supervision regulations.%在信托公司由"产品主导型"向"客户导向型"理财机构转变的思路指导下,银监会颁布新通知,要求信托公司构建以客户为核心,以专业化资产配置和财富管理为主要服务内容的信托营销模式。新的营销模式引起了行业的震动,有望解决银监会对信托公司以及第三方公司监管力度不够的难题。然而,新政策在营销人员从业资格、营销中心的限制、异地营销中心监管等三个方面依然存在漏洞,需要进一步完善监管法规。

  17. Regulatory Technology Development Plan - Sodium Fast Reactor: Mechanistic Source Term – Trial Calculation

    Energy Technology Data Exchange (ETDEWEB)

    Grabaskas, David [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Jerden, James [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Brunett, Acacia J. [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Denman, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Engineering Division; Clark, Andrew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Engineering Division; Denning, Richard S. [Consultant, Columbus, OH (United States)

    2016-10-01

    The potential release of radioactive material during a plant incident, referred to as the source term, is a vital design metric and will be a major focus of advanced reactor licensing. The U.S. Nuclear Regulatory Commission has stated an expectation for advanced reactor vendors to present a mechanistic assessment of the potential source term in their license applications. The mechanistic source term presents an opportunity for vendors to realistically assess the radiological consequences of an incident and may allow reduced emergency planning zones and smaller plant sites. However, the development of a mechanistic source term for advanced reactors is not without challenges, as there are often numerous phenomena impacting the transportation and retention of radionuclides. This project sought to evaluate U.S. capabilities regarding the mechanistic assessment of radionuclide release from core damage incidents at metal fueled, pool-type sodium fast reactors (SFRs). The purpose of the analysis was to identify, and prioritize, any gaps regarding computational tools or data necessary for the modeling of radionuclide transport and retention phenomena. To accomplish this task, a parallel-path analysis approach was utilized, as shown below. One path, led by Argonne and Sandia National Laboratories, sought to perform a mechanistic source term assessment using available codes, data, and models, with the goal to identify gaps in the current knowledge base. The second path, performed by an independent contractor, performed sensitivity analyses to determine the importance of particular radionuclides and transport phenomena in regards to offsite consequences. The results of the two pathways were combined to prioritize gaps in current capabilities.

  18. Outsourcing medical data analyses: can technology overcome legal, privacy, and confidentiality issues?

    Science.gov (United States)

    Brumen, Bostjan; Heričko, Marjan; Sevčnikar, Andrej; Završnik, Jernej; Hölbl, Marko

    2013-12-16

    Medical data are gold mines for deriving the knowledge that could change the course of a single patient's life or even the health of the entire population. A data analyst needs to have full access to relevant data, but full access may be denied by privacy and confidentiality of medical data legal regulations, especially when the data analyst is not affiliated with the data owner. Our first objective was to analyze the privacy and confidentiality issues and the associated regulations pertaining to medical data, and to identify technologies to properly address these issues. Our second objective was to develop a procedure to protect medical data in such a way that the outsourced analyst would be capable of doing analyses on protected data and the results would be comparable, if not the same, as if they had been done on the original data. Specifically, our hypothesis was there would not be a difference between the outsourced decision trees built on encrypted data and the ones built on original data. Using formal definitions, we developed an algorithm to protect medical data for outsourced analyses. The algorithm was applied to publicly available datasets (N=30) from the medical and life sciences fields. The analyses were performed on the original and the protected datasets and the results of the analyses were compared. Bootstrapped paired t tests for 2 dependent samples were used to test whether the mean differences in size, number of leaves, and the accuracy of the original and the encrypted decision trees were significantly different. The decision trees built on encrypted data were virtually the same as those built on original data. Out of 30 datasets, 100% of the trees had identical accuracy. The size of a tree and the number of leaves was different only once (1/30, 3%, P=.19). The proposed algorithm encrypts a file with plain text medical data into an encrypted file with the data protected in such a way that external data analyses are still possible. The results

  19. Application of Radiation Chemistry to Some Selected Technological Issues Related to the Development of Nuclear Energy.

    Science.gov (United States)

    Bobrowski, Krzysztof; Skotnicki, Konrad; Szreder, Tomasz

    2016-10-01

    The most important contributions of radiation chemistry to some selected technological issues related to water-cooled reactors, reprocessing of spent nuclear fuel and high-level radioactive wastes, and fuel evolution during final radioactive waste disposal are highlighted. Chemical reactions occurring at the operating temperatures and pressures of reactors and involving primary transients and stable products from water radiolysis are presented and discussed in terms of the kinetic parameters and radiation chemical yields. The knowledge of these parameters is essential since they serve as input data to the models of water radiolysis in the primary loop of light water reactors and super critical water reactors. Selected features of water radiolysis in heterogeneous systems, such as aqueous nanoparticle suspensions and slurries, ceramic oxides surfaces, nanoporous, and cement-based materials, are discussed. They are of particular concern in the primary cooling loops in nuclear reactors and long-term storage of nuclear waste in geological repositories. This also includes radiation-induced processes related to corrosion of cladding materials and copper-coated iron canisters, dissolution of spent nuclear fuel, and changes of bentonite clays properties. Radiation-induced processes affecting stability of solvents and solvent extraction ligands as well oxidation states of actinide metal ions during recycling of the spent nuclear fuel are also briefly summarized.

  20. Gene Technology: Also a Gender Issue. Views of Dutch Informed Women on Genetic Screening and Gene Therapy.

    Science.gov (United States)

    van Berkel, Dymphie; Klinge, Ineke

    1997-01-01

    The views of Dutch women on the implications of the analysis of the human genome were studied by questionnaire and interview. Although a serious lack of knowledge about the topic was found, interviews produced a broad range of problematic issues. Attention to gender implications of gene technology is needed. (Author/EMK)

  1. Methods for studying medical device technology and practitioner cognition : The case of user-interface issues with infusion pumps

    NARCIS (Netherlands)

    Schraagen, J.M.C.; Verhoeven, F.

    2013-01-01

    Purpose : The aims of this study were to investigate how a variety of research methods is commonly employed to study technology and practitioner cognition. User-interface issues with infusion pumps were selected as a case because of its relevance to patient safety. Methods : Starting from a Cognitiv

  2. Methods for studying medical device technology and practitioner cognition: the case of user-interface issues with infusion pumps

    NARCIS (Netherlands)

    Schraagen, J.M.C.; Verhoeven, F.

    2013-01-01

    Purpose The aims of this study were to investigate how a variety of research methods is commonly employed to study technology and practitioner cognition. User-interface issues with infusion pumps were selected as a case because of its relevance to patient safety. Methods Starting from a Cognitive S

  3. NRC regulatory initiatives

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, T.C. [Nuclear Regulatory Commission (United States)

    1989-11-01

    The US Nuclear Regulatory Commission (NRC) is addressing several low-level waste disposal issues that will be important to waste generators and to States and Compacts developing new disposal capacity. These issues include Greater-Than-Class C (GTCC) waste, mixed waste, below regulatory concern (BRC) waste, and the low-level waste data base. This paper discusses these issues and their current status.

  4. ECOLOGICAL, ECONOMIC AND SOCIAL ISSUES OF IMPLEMENTING CARBON DIOXIDE SEQUESTRATION TECHNOLOGIES IN THE OIL AND GAS INDUSTRY IN RUSSIA

    Directory of Open Access Journals (Sweden)

    Alexey Cherepovitsyn

    2016-04-01

    Full Text Available The objective of this paper is to define the main approaches to the implementation of carbon dioxide sequestration technologies in the oil and gas industry in Russia, and also to identify ecological, economic and social issues of their usage. Promotion of the technology of carbon dioxide (CO2 sequestration by means of capturing and injecting it into underground reservoirs is a promising mechanism of reducing carbon dioxide concentration. Carbon capture and storage (CCS technologies might be used to enhance oil recovery (EOR-CO2 and production by means of oil extraction and decreasing oil viscosity. Conceptual view of the potential of EOR-СО2 technologies within the context of oil and gas industry sustainable development are presented. Incentives of the CCS projects implementation are identified. On the basis of the conducted research a number of scientific research and practical areas of the CCS technology development are presented.

  5. Forensic DNA phenotyping : Regulatory issues

    NARCIS (Netherlands)

    Koops, E.J.; Schellekens, M.H.M.

    2008-01-01

    Forensic DNA phenotyping is an interesting new investigation method: crime-scene DNA is analyzed to compose a description of the unknown suspect, including external and behavioral features, geographic origin and perhaps surname. This method is allowed in some countries but prohibited in a few

  6. Forensic DNA phenotyping : Regulatory issues

    NARCIS (Netherlands)

    Koops, E.J.; Schellekens, M.H.M.

    2008-01-01

    Forensic DNA phenotyping is an interesting new investigation method: crime-scene DNA is analyzed to compose a description of the unknown suspect, including external and behavioral features, geographic origin and perhaps surname. This method is allowed in some countries but prohibited in a few others

  7. Technological Proficiency as a Key to Job Security. Trends and Issues Alert No. 6.

    Science.gov (United States)

    Imel, Susan

    Although not all current jobs require basic computer skills, technological advances in society have created new jobs and changed the ways many existing jobs are performed. Clearly, workers who are proficient in technology have a greater advantage in the current workplace and the need for technologically proficient workers will only continue to…

  8. Research for Practice: A Look at Issues in Technology for Second Language Learning

    Science.gov (United States)

    Chapelle, Carol A.

    2010-01-01

    Over the past fourteen years, the pages of "Language Learning & Technology" have been filled with examples of research that take up the challenge of investigating second language learning through technology. It has been a period of expansion and growth in many ways. The expansion of technologies as well as their acceptance and use in language…

  9. To What Extent do Biology Textbooks Contribute to Scientific Literacy? Criteria for Analysing Science-Technology-Society-Environment Issues

    Directory of Open Access Journals (Sweden)

    Florbela M. Calado

    2015-10-01

    Full Text Available Our article proposes a set of six criteria for analysing science-technology-society-environment (STSE issues in regular textbooks as to how they are expected to contribute to students’ scientific literacy. We chose genetics and gene technology as fields prolific in STSE issues. We derived our criteria (including 26 sub-criteria from a literature review of the debate in science education on how to increase scientific literacy. We inspected the textbooks regarding the relationships between science, technology, society, and environment, and considered the presence of the decontextualized and socially neutral view of science as distorted view. We, qualitatively and quantitatively, applied our set of criteria to two German Biology textbooks and identified, in total, 718 STSE statements. Based on the frequencies of different criteria and sub-criteria in the textbooks, we drew conclusions concerning STSE issues and the underlying conceptions of science and technology, which might hinder the furtherance of scientific literacy. The applicability of our approach in other science education contexts is discussed.

  10. Critical issues in the choice of appropriate communication technology by Third World countries.

    Science.gov (United States)

    Sonaike, S A

    1987-01-01

    Recent experience suggests that the most appropriate form of technology for the Third World is an adapted, intermediate (less capital intensive) technology, founded around the needs of the people and utilizing readily available resources. When technology is used to relieve the symptoms of underdevelopment, a technologic misfit manifested in an overemphasis on prestige projects and the urban industrial sector results. Advanced communication technologies such as satellites are generally capital intensive, require high technical skills to install and maintain, and need sophisticated levels of management to function properly. These conditions are not easily met in the Third World, underscoring the need for intermediate technology as manifested in small and medium-sized business enterprises. Such an approach blends traditional technology, minimal capital, simple management structure, ample labor, and humane operation with the gains from sophisticated technology. Intermediate technology can serve as a good training ground for indigenous people in modern business methods and provide jobs for the unemployed. Most importantly, intermediate technology can function as an integral part of the larger society rather than as a loosely attached appendage grafted on by some foreign country. In the field of communication, such an approach would manifest itself in a willingness to operate professionally with simple portable cameras, an acceptance of the importance of rural radio broadcasting and village newspapers, a willingness on the part of trained media professionals to try out locally produced hardware, and an exploration of cheaper ways of producing textbooks.

  11. Gender issues in computer-supported learning: what we can learn from the gender; science and technology literature

    Directory of Open Access Journals (Sweden)

    Gwyneth Hughes

    2002-12-01

    Full Text Available This paper is a response to the article, 'Gender issues in computer-supported learning', in ALT-J 10 (1. I argue that the studies presented in the original paper could be enhanced by a more rigorous approach to gender that avoids universalizing identity, recognizes gender as a construction and which builds on previous research from gender, science and technology studies.

  12. Technologies for Self-Determination for Youth with Developmental Disabilities. Technologies for Voice: A Critical Issues Brief

    Science.gov (United States)

    Skouge, James R.; Kelly, Mary L.; Roberts, Kelly D.; Leake, David W.; Stodden, Robert A.

    2007-01-01

    This paper focuses on "technologies for voice" that are related to the self-determination of youth with developmental disabilities. The authors describe a self-determination model that values family-focused, community-referenced pedagogies employing "new media" to give voice to youth and their families. In line with the adage that a picture is…

  13. Demonstrating and Deploying Private Sector Technologies at DOE Sites - Issues to be Overcome

    Energy Technology Data Exchange (ETDEWEB)

    Bedick, R. C.

    2002-02-27

    The Department of Energy (DOE), Office of Environmental Management (EM) continues to pursue cost-effective, environmental cleanup of the weapons complex sites with a concomitant emphasis on deployment of innovative technologies as a means to this end. The EM Office of Science and Technology (OST) pursues a strategy that entails identification of technologies that have potential applications throughout the DOE complex: at multiple DOE sites and at multiple facilities on those sites. It further encourages a competitive procurement process for the various applications entailed in the remediation of a given facility. These strategies require a competitive private-sector supplier base to help meet EM needs. OST supports technology development and deployment through investments in partnerships with private industry to enhance the acceptance of their technology products within the DOE market. Since 1992, OST and the National Energy Technology Laboratory (NETL) have supported the re search and development of technology products and services offered by the private sector. During this time, NETL has managed over 140 research and development projects involving industrial and university partners. These projects involve research in a broad range of EM related topics, including deactivation and decommissioning, characterization, monitoring, sensors, waste separation, groundwater remediation, robotics, and mixed waste treatment. Successful partnerships between DOE and Industry have resulted in viable options for EM's cleanup needs, and require continued marketing efforts to ensure that these technology solutions are used at multiple DOE sites and facilities.

  14. Ethical Issues in the Introduction of New Technologies: From Mis to POEM.

    Science.gov (United States)

    Ferreres, Alberto R; Patti, Marco

    2015-07-01

    The ethical debate regarding the introduction of new technologies in the surgical health care environment is discussed in this manuscript, with a special emphasis on minimally invasive and NOTES procedures for the treatment of esophageal achalasia. It offers an overview of the ethical principles and considerations about the implementation of new techniques and technologies.

  15. Trends and Issues in Educational Technology Research in Saudi Higher Education: A Meta-Analysis Review

    Science.gov (United States)

    Alkraiji, Abdullah; Eidaroos, Abdulhadi

    2016-01-01

    As Information Technology expands, all industries and fields in Saudi Arabia are experiencing reduced costs and improvements in the efficiency and effectiveness of operations in various systems. This has positioned the higher education sector in Saudi Arabia as the land of opportunity in terms of educational technology and its ability to support…

  16. Current Technology Trends and Issues among Health and Physical Education Professionals

    Science.gov (United States)

    Krause, Jennifer M.; Franks, Hillary; Lynch, Brandy

    2017-01-01

    Health and physical education professionals who implement technology appropriately can contribute to helping students become physically educated individuals (NASPE, 2009). It is imperative that professionals be knowledgeable and resourceful in how to integrate technology effectively, but it is unclear what current challenges professionals face in…

  17. A Technology Assessment of Personal Computers. Vol. III: Personal Computer Impacts and Policy Issues.

    Science.gov (United States)

    Nilles, Jack M.; And Others

    A technology assessment of personal computers was conducted to study both the socially desirable and undesirable impacts of this new technology in three main areas: education, employment, and international trade. Information gleaned from this study was then used to generate suggestions for public policy options which could influence these impacts.…

  18. Spanish Secondary-School Science Teachers' Beliefs about Science-Technology-Society (STS) Issues

    Science.gov (United States)

    Vazquez-Alonso, Angel; Garcia-Carmona, Antonio; Manassero-Mas, Maria Antonia; Bennassar-Roig, Antoni

    2013-01-01

    This study analyzes the beliefs about science-technology-society, and other Nature of Science (NOS) themes, of a large sample (613) of Spanish pre- and in-service secondary education teachers through their responses to 30 items of the Questionnaire of Opinions on Science, Technology and Society. The data were processed by means of a multiple…

  19. Increased susceptibility to the innovative energy-saving technologies in the oil and fat industry by improving regulatory and institutional framework

    OpenAIRE

    V.G. Dyuzhev; Popov, N A

    2014-01-01

    The aim of the article. The aim of the article is to increase the susceptibility to innovative energy saving technologies in oil and fat industry basing on the formation of organizational and economic section of the regulatory framework of energy efficiency programs. The results of the analysis. Angle susceptibility innovative energy conservation program in the oilseed industry is analyzed in this article. Stages of formation of the organizational and economic section sectoral energy savin...

  20. IN SITU AND EX SITU BIODEGRADATION TECHNOLOGIES FOR REMEDIATION OF CONTAMINATED SITES [ENGINEERING ISSUE)

    Science.gov (United States)

    Bioremediation is a grouping of technologies that use microbiota (typically, heterotrophic bacteria and fungi) to degrade or transform hazardous contaminants to materials such as carbon dioxide, water, inorganic salts, microbial biomass, and other byproducts that may be less haza...

  1. Information technology issues in an era of greater state responsibilities: policy concerns for seniors.

    Science.gov (United States)

    Shrewsbury, Carolyn M

    2002-01-01

    Five areas of state information technology policy are of special concern to seniors and senior service providers: obtaining access; closing the digital divide; developing information management systems; creating portals; and maintaining privacy. Increasing their activities in each of these areas, states continue to vary considerably in their responsiveness to meeting the challenge of including older adults, especially those living in rural areas, with the benefits of information technology.

  2. Influence of regulatory uncertainty on capacity investments – Are investments in new technologies a risk mitigation measure?

    OpenAIRE

    Schwark, Bastian

    2009-01-01

    Understanding the investment decisions of power companies is vital for a regulator as particularly deficient investments in generation capacity could jeopardize the market in the long run. Considering potential risks that could hamper investments, the paper focuses on regulatory uncertainty and firms’ behavior to mitigate risk. The question of how uncertainty influences investment decisions has been explained by a number of researchers. In the specific case of regulatory uncertainty it is ag...

  3. Historical review of clinical vaccine studies at Oswaldo Cruz Institute and Oswaldo Cruz Foundation - technological development issues

    Directory of Open Access Journals (Sweden)

    Reinaldo de Menezes Martins

    2015-02-01

    Full Text Available This paper presents, from the perspective of technological development and production, the results of an investigation examining 61 clinical studies with vaccines conducted in Brazil between 1938-2013, with the participation of the Oswaldo Cruz Institute (IOC and the Oswaldo Cruz Foundation (Fiocruz. These studies have been identified and reviewed according to criteria, such as the kind of vaccine (viral, bacterial, parasitic, their rationale, design and methodological strategies. The results indicate that IOC and Fiocruz have accumulated along this time significant knowledge and experience for the performance of studies in all clinical phases and are prepared for the development of new vaccines products and processes. We recommend national policy strategies to overcome existing regulatory and financing constraints.

  4. Colleges of Applied Arts and Technology of Ontario. Background Papers on Current Issues.

    Science.gov (United States)

    Association of Colleges of Applied Arts and Technology of Ontario, Willowdale.

    Background information is provided on a number of conditions affecting Ontario's community colleges. The first section, dealing with financial issues, considers the college environment in the 1980s; examines the provincial government's perspective on priorities, the allocation process, government funding, and budgetary expenditures and trends; and…

  5. The Technology of Teacher Licensing Testing: A Discussion of Issues and Recommendations for Practice.

    Science.gov (United States)

    Crehan, Kevin D.; Hess, Robert K.; D'Agostino, Jerome V.

    This paper focuses on teacher testing issues related to job analysis, test specification development, reliability, and validity. It emphasizes the conceptualization and operational definition of appropriate validity evidence to assess the quality of licensure testing decisions. It is suggested that the process of job, or practice, analysis would…

  6. Critical issues for the application of integrated MEMS/CMOS technologies to inertial measurement units

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.H.; Ellis, J.R.; Montague, S.; Allen, J.J.

    1997-03-01

    One of the principal applications of monolithically integrated micromechanical/microelectronic systems has been accelerometers for automotive applications. As integrated MEMS/CMOS technologies such as those developed by U.C. Berkeley, Analog Devices, and Sandia National Laboratories mature, additional systems for more sensitive inertial measurements will enter the commercial marketplace. In this paper, the authors will examine key technology design rules which impact the performance and cost of inertial measurement devices manufactured in integrated MEMS/CMOS technologies. These design parameters include: (1) minimum MEMS feature size, (2) minimum CMOS feature size, (3) maximum MEMS linear dimension, (4) number of mechanical MEMS layers, (5) MEMS/CMOS spacing. In particular, the embedded approach to integration developed at Sandia will be examined in the context of these technology features. Presently, this technology offers MEMS feature sizes as small as 1 {micro}m, CMOS critical dimensions of 1.25 {micro}m, MEMS linear dimensions of 1,000 {micro}m, a single mechanical level of polysilicon, and a 100 {micro}m space between MEMS and CMOS. This is applicable to modern precision guided munitions.

  7. Critical issues for the application of integrated MEMS/CMOS technologies to inertial measurement units

    Science.gov (United States)

    Smith, James H.; Montague, Stephen; Allen, James J.; Ellis, J. R.; Burgett, Scott M.

    1997-06-01

    One of the principal applications of monolithically integrated micromechanical/microelectronic systems has been accelerometers for automotive applications. As integrated MEMS/CMOS technologies such as those developed by U.C. Berkeley, Analog Devices, and Sandia National Laboratories mature, additional systems for more sensitive inertial measurements will enter the commercial marketplace. In this paper, we will examine the key technology design rules which impact the performance and cost of inertial measurement devices manufactured in integrated MEMS/CMOS technologies. These design parameters include: (1) Minimum MEMS feature size, (2) Minimum CMOS feature size, (3) Maximum MEMS linear dimension, (4) Number of mechanical MEMS layers, and (5) MEMS/CMOS spacing. In particular, the embedded approach to integration developed at Sandia will be examined in the context of these technology features. Presently, this technology offers MEMS feature sizes as small as 1 micrometers , CMOS critical dimensions of 1.25 micrometers , MEMS linear dimensions of 1000 micrometers , a single mechanical level of polysilicon, and a 100 micrometers space between MEMS and CMOS.

  8. Coupling renewables via hydrogen into utilities: Temporal and spatial issues, and technology opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Iannucci, J.J.; Horgan, S.A.; Eyer, J.M. [Distributed Utility Associates, San Ramon, CA (United States)] [and others

    1996-10-01

    This paper discusses the technical potential for hydrogen used as an energy storage medium to couple time-dependent renewable energy into time-dependent electric utility loads. This analysis will provide estimates of regional and national opportunities for hydrogen production, storage and conversion, based on current and near-term leading renewable energy and hydrogen production and storage technologies. Appropriate renewable technologies, wind, photovoltaics and solar thermal, are matched to their most viable regional resources. The renewables are assumed to produce electricity which will be instantaneously used by the local utility to meet its loads; any excess electricity will be used to produce hydrogen electrolytically and stored for later use. Results are derived based on a range of assumptions of renewable power plant capacity and fraction of regional electric load to be met (e.g., the amount of hydrogen storage required to meet the Northwest region`s top 10% of electric load). For each renewable technology national and regional totals will be developed for maximum hydrogen production per year and ranges of hydrogen storage capacity needed in each year (hydroelectric case excluded). The sensitivity of the answers to the fraction of peak load to be served and the land area dedicated for renewable resources are investigated. These analyses can serve as a starting point for projecting the market opportunity for hydrogen storage and distribution technologies. Sensitivities will be performed for hydrogen production, conversion. and storage efficiencies representing current and near-term hydrogen technologies.

  9. Pervasive and Mobile Sensing and Computing for Healthcare Technological and Social Issues

    CERN Document Server

    Postolache, Octavian

    2013-01-01

    The pervasive healthcare system focus towards achieving two specific goals: the availability of eHealth applications and medical information anywhere and anytime and the invisibility of computing. Furthermore, pervasive health system encompasses new types of sensing and communication of health information as well as new type of interactions among health providers and people, among patients, among patients and researchers and patients and corporations. This book aims at promoting the discussion on current trends in technologies and concepts that help integrate health monitoring and healthcare more seamlessly to our everyday lives, regardless of space and time, but also present cutting edge perspectives and visions to highlight future development. The book presents not only the state of the art technologies and solutions to tackle the critical challenges faced by the building and development of the pervasive health system but also potential impact on society at social, medical and technological level.   

  10. APEC energy security and sustainable development through efficiency and diversity - economic issues in technology R & D, adoption and transfer

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, L.; Curtotti, R.; Austin, A.

    2007-04-15

    The Asia Pacific Economic Cooperation forum (APEC) has an important role to play in strengthening regional economic cooperation and in addressing the regional energy security and sustainable energy development issues that have become more prominent in recent years. Key objectives in this report are to present an overview of the challenges facing APEC economies in meeting the region's growing energy requirements, with a focus on the energy requirements of the APEC stationary energy sector, and to assess the role that cleaner fuels and energy technologies can play in achieving a more secure and sustainable energy sector in the APEC region. The report also examines barriers to investment and policy options that encourage the development and deployment of energy technologies that can enhance energy security and environmental sustainability in the APEC region. Appendix D deals with coal fired power generation technologies. The report was prepared in anticipation of the eighth meeting of the APEC Energy Ministers Meeting. To support energy policy formulation by energy ministers, relevant background information is provided on clean and energy efficient technologies, alternative and renewable fuels, and environmentally sustainable energy technologies. 59 refs., 24 figs., 19 tabs., 5 apps.

  11. Status and issue of coal mine safety technology development in Japan and international co-operation

    Energy Technology Data Exchange (ETDEWEB)

    Nakmura, K. [Ministry of International Trade and Industry, Tokyo (Japan). Mine Safety Division, Environmental Protection and Industrial Location Bureau

    2001-03-01

    Recent trends in coal mine accidents in Japan are reviewed and the incident of mine fire at the Ikeshima coal mine in Nagasaki Prefecture in February 2000 reported. An overview is given of safety projects underway in Japan or jointly with Australia. Cooperative projects to prevent spontaneous combustion to develop underground monitoring techniques, and to transfer safety technologies from Japan abroad are outlined. Other projects carried out by the Japan International Cooperation Agency (JICA) are listed. Japan's long-term policy for safety technology development is outlined. 4 figs., 6 tabs.

  12. A Holistic Approach for Addressing the Issue of Effective Technology Transfer in the Frame of Climate Change

    Directory of Open Access Journals (Sweden)

    Charikleia Karakosta

    2016-06-01

    Full Text Available Climate change policy and sustainable development issues and goals are closely intertwined. Recognizing the dual relationship between sustainable development and climate change points to a need for the exploration of actions that jointly address sustainable development and climate change. Technology transfer is considered an issue with growing interest worldwide and has been recognized as the key in supporting countries to achieve sustainable development, while addressing climate change challenges. This study presents an integrated decision support methodological framework for the formulation and evaluation of activities to promote technology transfer, as well as the provision of clear recommendations and strategies for framing specific policy in the context of climate change. The philosophy of the proposed approach, under the name: assess-identify-define (AID, consists of three components, where each one focuses on a particular problem. The methodology is integrated using appropriate tools in the information decision support system for effective technology transfer (DSS-ΕTT. The pilot application of the proposed methodology, in five representative developing countries, provided the possibility to evaluate the characteristics of the adopted methodology in terms of completeness, usability, extensionality, as well as analysis of results reliability.

  13. Do We Give It to Them, and What Happens If We Do? Issues Concerning Technology Transfers

    Science.gov (United States)

    2008-05-22

    even for government purposes, causing firearms to nearly vanish from Japan. The samurai controlled government refrained from adopting this new...apparently effective technology because it contrasted with the historic samurai culture. The firearm was denigrated to the point of near extinction

  14. Didactics of Information Technology (IT) in a Science Degree: Conceptual Issues and Practical Application

    Science.gov (United States)

    Miliszewska, Iwona; Venables, Anne; Tan, Grace

    2010-01-01

    Information technology has been transforming various disciplines of life sciences and physical sciences as a tool (for "doing" science) and a technique (for conducting experiments and creating models). This evolution in the application of IT in science demands that science students be equipped with appropriate IT skills and that the…

  15. Assistive Technology for Students with Disabilities: A Legal Analysis of Issues

    Science.gov (United States)

    Etscheidt, Susan Larson

    2016-01-01

    Individualized Education Program (IEP) teams are required by the Individuals with Disabilities Education Act (IDEA) to consider a student's need for assistive technology (AT). Despite this legal requirement, AT supports are often not available to students with disabilities. Many students with disabilities and their families have addressed the…

  16. Ethical Issues Related to the Use/Non-Use of Assistive Technologies

    Science.gov (United States)

    Cook, Albert M.

    2009-01-01

    Assistive technologies (AT) can provide significant assistance in accomplishing the tasks of daily living for persons who have disabilities. Five types of ethical principles underlie the distribution and use of AT: beneficence, nonmaleficence, justice, autonomy and fidelity. Beneficence, nonmaleficence, and justice, most directly affect the…

  17. International Linear Collider Steering Committee issues charge to Technology Recommendation Panel

    CERN Multimedia

    2003-01-01

    "Following its November 19 meeting in Paris, the International Linear Collider Steering Committee, a subcommittee of the International Committee for Future Accelerators, has published the charge http://www.fnal.gov/directorate/icfa/ITRP_Charge.pdf to the International Technology Recommendation Panel appointed by ICFA" (2 paragraphs).

  18. Science and Technology Issues Relating to Data Quality in C2 Systems

    Science.gov (United States)

    2011-06-01

    University, Center for Technology and National Security Policy: Fort Lesley J. McNair, Washington, DC, 20319. 28. MacPherson, M., Roberts Ridge : A Story of...Army. 34. Allen, M.D., C. Macheret, and M.A. Malloy , C2 Core and UCore Message Design Capstone: Interoperable Message Structure. 2009. 35. Guthrie

  19. Current Issues and Trends in Multidimensional Sensing Technologies for Digital Media

    Science.gov (United States)

    Nagata, Noriko; Ohki, Hidehiro; Kato, Kunihito; Koshimizu, Hiroyasu; Sagawa, Ryusuke; Fujiwara, Takayuki; Yamashita, Atsushi; Hashimoto, Manabu

    Multidimensional sensing (MDS) technologies have numerous applications in the field of digital media, including the development of audio and visual equipment for human-computer interaction (HCI) and manufacture of data storage devices; furthermore, MDS finds applications in the fields of medicine and marketing, i.e., in e-marketing and the development of diagnosis equipment.

  20. IEA Wind Task 23 Offshore Wind Technology and Deployment. Subtask 1 Experience with Critical Deployment Issues. Final Technical Report

    DEFF Research Database (Denmark)

    Lemming, Jørgen Kjærgaard

    The final report for IEA Wind Task 23, Offshore Wind Energy Technology and Deployment, is made up of two separate reports: Subtask 1: Experience with Critical Deployment Issues and Subtask 2: Offshore Code Comparison Collaborative (OC3). The Subtask 1 report included here provides background...... information and objectives of Task 23. It specifically discusses ecological issues and regulation, electrical system integration and offshore wind, external conditions, and key conclusions for Subtask 1. The Subtask 2 report covers OC3 background information and objectives of the task, OC3 benchmark exercises...... of aero-elastic offshore wind turbine codes, monopile foundation modeling, tripod support structure modeling, and Phase IV results regarding floating wind turbine modeling....

  1. Some issues involved in designing a 1 TeV (c. m. ) e/sup + -/ linear collider using conventional technology

    Energy Technology Data Exchange (ETDEWEB)

    Loew, G.A.

    1986-02-01

    Some of the crucial issues are discussed which are raised when one wants to use conventional technology to design a 1 TeV electron-positron linear collider with a luminosity of 2 x 10/sup 32/ cm/sup -2/sec/sup -1/. By conventional technology is meant that the process of acceleration is achieved as is usual in common electron linacs - namely that the electron and positron bunches receive their energy from rf fields stored in copper structures at room temperature. The beam-related problems and linac-related problems are treated separately. What happen as one goes to gradients and frequencies higher that those of the SLC are considered, in an attempt to decrease overall length and power consumption. The rf and other problems that one confronts as one goes to higher energies are illustrated. 19 refs., 12 figs., 2 tabs. (LEW)

  2. Delivering drugs to the central nervous system: a medicinal chemistry or a pharmaceutical technology issue?

    Science.gov (United States)

    Ricci, Maurizio; Blasi, Paolo; Giovagnoli, Stefano; Rossi, Carlo

    2006-01-01

    This review aims to summarize the non-invasive approaches employed in delivering drugs to the central nervous system which is severely hindered by the presence of the blood-brain barrier (BBB) that limits molecular permeation. Particular attention will be placed on the several available strategies for delivering drugs into the brain, through circumvention of the BBB, in order to critically address the medicinal chemistry and the pharmaceutical technology contributions.

  3. The Bayh-Dole Act: Selected Issues in Patent Policy and the Commercialization of Technology

    Science.gov (United States)

    2009-02-03

    Perhaps most illustrative of the influence of the Bayh-Dole Act on small business is the biotechnology industry . According to Dr. Bernadine Healy...sector.65 The biotechnology industry primarily is composed of small firms that are developing technologies and techniques derived from R&D funded by NIH...important as an economic force in our economy.... ”68 In a report by Battelle for the Biotechnology Industry Organization (BIO), analysts found that

  4. Technology, Implementation and Policy Issues for the Modernisation of GPS and its Role in a GNSS

    Science.gov (United States)

    McDonald, Keith D.

    1998-09-01

    This and the following six papers were selected from the many papers presented at the 9th World Congress of the International Association of Institutes of Navigation (IAIN) held in Amsterdam, The Netherlands, 17-21 November 1997.During the past several years, a number of important investigations, policy initiatives and national commitments relating to the future of GPS, GLONASS and their augmentations have occurred. Substantive and on-going studies of the character and configuration of a Global Navigation Satellite System (GNSS) have also been evaluated worldwide, especially by the International Civil Aviation Organization (ICAO). These efforts have been principally directed toward the definition of near- and far-term GNSS implementations that meet the needs and concerns of the international community. This paper briefly reviews some of the investigations and addresses, in particular, the concerns and requirements that may affect the future capabilities and the dual (civil/military) character of GPS. The main issues relating to the modernisation of GPS and its subsequent transition to a component of a GNSS with a viable international character are presented. These include a discussion of new signal structure options, certain changes in operating frequencies, increased signal power levels, other system alternatives and their potential impact on system performance. International issues are briefly addressed, including future performance capabilities, assurance of service, economic participation and benefit, reasonable cost, standards and international participation.

  5. Implementation workshop of WHO guidelines on evaluation of malaria vaccines: Current regulatory concepts and issues related to vaccine quality, Pretoria, South Africa 07 Nov 2014.

    Science.gov (United States)

    Ho, Mei Mei; Baca-Estrada, Maria; Conrad, Christoph; Karikari-Boateng, Eric; Kang, Hye-Na

    2015-08-26

    The current World Health Organization (WHO) guidelines on the quality, safety and efficacy of recombinant malaria vaccines targeting the pre-erythrocytic and blood stages of Plasmodium falciparum were adopted by the WHO Expert Committee on Biological Standardization in 2012 to provide guidance on the quality, nonclinical and clinical aspects of recombinant malaria vaccines. A WHO workshop was organised to facilitate implementation into African (national/regional) regulatory practices, of the regulatory evaluation principles outlined in the guidelines regarding quality aspects. The workshop was used also to share knowledge and experience on regulatory topics of chemistry, manufacturing and control with a focus on vaccines through presentations and an interactive discussion using a case study approach. The basic principles and concepts of vaccine quality including consistency of production, quality control and manufacturing process were presented and discussed in the meeting. By reviewing and practicing a case study, better understanding on the relationship between consistency of production and batch release tests of an adjuvanted pre-erythrocytic recombinant malaria vaccine was reached. The case study exercise was considered very useful to understand regulatory evaluation principles of vaccines and a suggestion was made to WHO to provide such practices also through its Global Learning Opportunities for Vaccine Quality programme.

  6. Mining and Reclamation Technology Symposium

    Energy Technology Data Exchange (ETDEWEB)

    None Available

    1999-06-24

    The Mining and Reclamation Technology Symposium was commissioned by the Mountaintop Removal Mining/Valley Fill Environmental Impact Statement (EIS) Interagency Steering Committee as an educational forum for the members of the regulatory community who will participate in the development of the EIS. The Steering Committee sought a balanced audience to ensure the input to the regulatory community reflected the range of perspectives on this complicated and emotional issue. The focus of this symposium is on mining and reclamation technology alternatives, which is one of eleven topics scheduled for review to support development of the EIS. Others include hydrologic, environmental, ecological, and socio-economic issues.

  7. Syngas production for gas-to-liquids applications. Technologies, issues and outlook

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, D.J.; Simbeck, D.R.; Karp, A.D.; Dickenson, R.L. [SFA Pacific, Inc., 444 Castro St., Suite 720, 94041 Mountain View, CA (United States)

    2001-06-01

    The main gas-to-liquids (GTL) interest now is in Fischer-Tropsch (F-T) synthesis of hydrocarbons. While synthesis gas (syngas) for GTL can be produced from any carbon-based feedstock (hydrocarbons, coal, petroleum coke, biomass), the lowest cost routes to syngas so far are based on natural gas. Thus, the focus for GTL has been largely on associated gas, so-called stranded or remotely located gas reserves, and larger gas reserves that are not currently being economically exploited. The principal technologies for producing syngas from natural gas are: catalytic steam methane reforming (SMR), two-step reforming, autothermal reforming (ATR), partial oxidation (POX), and heat exchange reforming. The distinguishing characteristics of these technologies and their commercial uses are discussed in this paper. Ongoing R and D efforts to develop lower-cost syngas generation technologies are also briefly discussed. Relevant commercial experience with large-scale syngas generation for GTL is also discussed. As a frame of reference, in terms of syngas flow rates, a 20,000 b/day F-T plant would be comparable to three 2500 mt/day methanol plants. Single-train methanol plants are now producing more than 2500 t/day-and plants approaching 3000 mt/day have been announced. The projected relative economies of scale of the various syngas production technologies indicate that two-step reforming and ultimately, ATR, should be the technologies of choice for large-scale GTL plants. Nevertheless, for a 20,000 b/day F-T liquids plant, capital charges still dominate the manufacturing costs. Syngas production (oxygen plant and reforming) comprises half of the total capital cost of this size GTL plant. While air-blown reforming eliminates the expensive oxygen plant, air-blown reforming is unlikely to be competitive with, or offer the flexibility of, oxygen-blown reforming. The reasons for this conclusion are discussed. The proposed and future GTL facilities should be substantially less costly

  8. Syngas production for gas-to-liquids applications. Technologies, issues and outlook

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, D.J.; Simbeck, D.R.; Karp, A.D.; Dickenson, R.L. [SFA Pacific, Inc., 444 Castro St., Suite 720, 94041 Mountain View, CA (United States)

    2001-06-01

    The main gas-to-liquids (GTL) interest now is in Fischer-Tropsch (F-T) synthesis of hydrocarbons. While synthesis gas (syngas) for GTL can be produced from any carbon-based feedstock (hydrocarbons, coal, petroleum coke, biomass), the lowest cost routes to syngas so far are based on natural gas. Thus, the focus for GTL has been largely on associated gas, so-called stranded or remotely located gas reserves, and larger gas reserves that are not currently being economically exploited. The principal technologies for producing syngas from natural gas are: catalytic steam methane reforming (SMR), two-step reforming, autothermal reforming (ATR), partial oxidation (POX), and heat exchange reforming. The distinguishing characteristics of these technologies and their commercial uses are discussed in this paper. Ongoing R and D efforts to develop lower-cost syngas generation technologies are also briefly discussed.Relevant commercial experience with large-scale syngas generation for GTL is also discussed. As a frame of reference, in terms of syngas flow rates, a 20,000 b/day F-T plant would be comparable to three 2500 mt/day methanol plants. Single-train methanol plants are now producing more than 2500 t/day-and plants approaching 3000 mt/day have been announced. The projected relative economies of scale of the various syngas production technologies indicate that two-step reforming and ultimately, ATR, should be the technologies of choice for large-scale GTL plants. Nevertheless, for a 20,000 b/day F-T liquids plant, capital charges still dominate the manufacturing costs. Syngas production (oxygen plant and reforming) comprises half of the total capital cost of this size GTL plant. While air-blown reforming eliminates the expensive oxygen plant, air-blown reforming is unlikely to be competitive with, or offer the flexibility of, oxygen-blown reforming. The reasons for this conclusion are discussed.The proposed and future GTL facilities should be substantially less costly than

  9. Regulatory agencies and regulatory risk

    OpenAIRE

    Knieps, Günter; Weiß, Hans-Jörg

    2007-01-01

    The aim of this paper is to show that regulatory risk is due to the discretionary behaviour of regulatory agencies, caused by a too extensive regulatory mandate provided by the legislator. The normative point of reference and a behavioural model of regulatory agencies based on the positive theory of regulation are presented. Regulatory risk with regard to the future behaviour of regulatory agencies is modelled as the consequence of the ex ante uncertainty about the relative influence of inter...

  10. Optical waveguiding and applied photonics technological aspects, experimental issue approaches and measurements

    CERN Document Server

    Massaro, Alessandro

    2012-01-01

    Optoelectronics--technology based on applications light such as micro/nano quantum electronics, photonic devices, laser for measurements and detection--has become an important field of research. Many applications and physical problems concerning optoelectronics are analyzed in Optical Waveguiding and Applied Photonics.The book is organized in order to explain how to implement innovative sensors starting from basic physical principles. Applications such as cavity resonance, filtering, tactile sensors, robotic sensor, oil spill detection, small antennas and experimental setups using lasers are a

  11. Development of Animation Education Issues and the Solutions with the Combination of Computer Technology

    Institute of Scientific and Technical Information of China (English)

    Xinchen HE

    2015-01-01

    This paper argues that the development of modern animation education of social concern, animation education should reflect the characteristics of the times. With the development of the law of computer technology, it is to develop appropriate education and training goals, openness of modern education, diversity, combined with interactive features such as animation education laws governing the operation of the market in order to achieve quality education of animation education. Emphasizes the comprehensive development and training of talents with professional qualities, is the only way for the development of Chinese animation.

  12. Special Issue: Software-engineering, Properites of Language and Aspect Technologies

    DEFF Research Database (Denmark)

    Bergmans, Lodewijk; Gybels, Kris; Ernst, Erik

    2008-01-01

    engineering activities and products is often a question of balancing contradictory forces and ideals. It is therefore also critical to understand these trade-offs. Aspect technologies aim also particularly at the improvement of software engineering properties, especially the above mentioned modularity...... of pointcuts, and the complexity of novel and innovative general-purpose pointcut languages. This paper proposes an interface for user-defined pointcuts, which allows for the definition of new, possibly domain-specific, kinds of pointcuts without extending the language. The second paper, "Developing Law...

  13. NEW HOPE AND TECHNOLOGICAL ISSUES ON VOICE AND VIDEO OVER ATM

    Directory of Open Access Journals (Sweden)

    Dr.S.S.Riaz Ahamed

    2010-12-01

    Full Text Available Changes in the structure of the telecommunications industry and market conditions have brought new opportunities and challenges for network operators and public service providers. Networks that have been primarily focused on providing better voice services are evolving to meet new multimedia communications challenges and competitive pressures. Services based on asynchronous transfer mode (ATM provide the flexible infrastructure essential for success in this evolving market. ATM, which was once envisioned as the technology of future public networks, is now a reality, with service providers around the world introducing and rolling out ATM and ATM–based services.

  14. The Third Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies

    Directory of Open Access Journals (Sweden)

    P. Justin eRossi

    2016-04-01

    Full Text Available This review summarizes the most contemporary clinical, electrophysiological, imaging, and computational work on DBS for the treatment of neurological and neuropsychiatric disease. Significant innovations of the past year are emphasized; these advances were presented at the 3rd Annual Deep Brain Stimulation Think Tank. The Think Tank’s contributors represent a unique multidisciplinary ensemble of expert neurologists, neurosurgeons, neuropsychologists, psychiatrists, scientists, engineers, and members of industry. Presentations and discussions covered a broad range of topics, including policy and advocacy considerations for the future of DBS, connectomic approaches to DBS targeting, developments in electrophysiology and related strides toward responsive DBS systems, and recent developments in sensor and device technologies.

  15. Spanish Secondary-School Science Teachers' Beliefs About Science-Technology-Society (STS) Issues

    Science.gov (United States)

    Vázquez-Alonso, Ángel; García-Carmona, Antonio; Manassero-Mas, María Antonia; Bennàssar-Roig, Antoni

    2013-05-01

    This study analyzes the beliefs about science-technology-society, and other Nature of Science (NOS) themes, of a large sample (613) of Spanish pre- and in-service secondary education teachers through their responses to 30 items of the Questionnaire of Opinions on Science, Technology and Society. The data were processed by means of a multiple response model to generate the belief indices used as the bases for subsequent quantitative and qualitative analyses. Other studies have reported a negative profile of teachers' understanding in this area, but the diagnosis emerging from the present work is more complex. There was a mix of appropriate beliefs coexisting with others that are inappropriate on the topics analyzed. The overall assessment, however, is negative since clearly teachers need to have a better understanding of these questions. There were scant differences between the pre- and in-service teachers, and hence no decisive evidence that the practice of teaching contributes to improving the in-service teachers' understanding. These results suggest there is an urgent need to bring the initial and continuing education of science teachers up to date to improve their understanding of these topics of science curricula, and thus improve the teaching of science.

  16. Issues involved in attempting to develop independent learning in pupils working on technological projects

    Science.gov (United States)

    Barak, Moshe

    2004-02-01

    This research addresses the impact of technological projects at high school on pupils' learning. The participants were sixty low-mid achieving pupils who worked for one year on final projects for matriculation exams. Data were collected through observations of laboratory lessons, interviews with pupils and teachers, and analysis of pupils' projects and portfolios. In the modern technological laboratory, pupils experience design, construction and improvement of sophisticated systems, in a rich learning environment. From being fully dependent on their teachers, pupils might gradually develop to become more autonomous learners and creative thinkers. A three-stage model is suggested aimed to help teachers adjust their supervision approach to the pupils' conceptual development. A pupil at the 'show me' stage needs a 'direct supervision' approach; a pupil at the 'let's think together' stage needs a 'collaborative supervision' approach; a pupil at the 'trust me' stage needs a 'nondirective supervision'. In projects carried out within mandatory exams, pupils are motivated not only by internal rewards, but also by being evaluated objectively and awarded a formal credit for their achievements.

  17. Lymph node-positive prostate cancer: current issues, emerging technology and impact on clinical outcome.

    Science.gov (United States)

    Adams, Julia; Cheng, Liang

    2011-09-01

    Lymph node metastasis in patients with prostate cancer indicates a poorer prognosis compared with patients without lymph node metastasis; however, some patients with node-positive disease have long-term survival. Many studies have attempted to discern what characteristics of lymph node metastasis are prognostically significant. These characteristics include nodal tumor volume, number of positive lymph nodes, lymph node density, extranodal extension, lymphovascular invasion and tumor dedifferentiation. Favorable characteristics of regional lymph node involvement included a smaller tumor size and smaller tumor volume. However, the current staging system for prostate cancer does not provide different subclassifications for patients with node-positive prostate cancer. In recent years numerous advanced technologies for the detection of lymph node metastasis have been developed, including molecular imaging techniques and the CellSearch Circulating Tumor Cell System. With the increased detection of patients with prostate cancer, emergence of new technology to identify lymph node metastasis and the number of radical prostatectomies being performed on the rise, subclassifying patients with lymph node-positive disease is imperative. Subclassification would provide a better picture of patient prognosis and allow for a better understanding of targeted therapies to treat patients with lymph node metastasis.

  18. Using online pedagogy to explore student experiences of Science-Technology-Society-Environment (STSE) issues in a secondary science classroom

    Science.gov (United States)

    Ayyavoo, Gabriel Roman

    With the proliferation of 21st century educational technologies, science teaching and learning with digitally acclimatized learners in secondary science education can be realized through an online Science-Technology-Society-Environment (STSE)-based issues approach. STSE-based programs can be interpreted as the exploration of socially-embedded initiatives in science (e.g., use of genetically modified foods) to promote the development of critical cognitive processes and to empower learners with responsible decision-making skills. This dissertation presents a case study examining the online environment of a grade 11 physics class in an all-girls' school, and the outcomes from those online discursive opportunities with STSE materials. The limited in-class discussion opportunities are often perceived as low-quality discussions in traditional classrooms because they originate from an inadequate introduction and facilitation of socially relevant issues in science programs. Hence, this research suggests that the science curriculum should be inclusive of STSE-based issue discussions. This study also examines the nature of students' online discourse and, their perceived benefits and challenges of learning about STSE-based issues through an online environment. Analysis of interviews, offline classroom events and online threaded discussion transcripts draws from the theoretical foundations of critical reflective thinking delineated in the Practical Inquiry (P.I.) Model. The PI model of Cognitive Presence is situated within the Community of Inquiry framework, encompassing two other core elements, Teacher Presence and Social Presence. In studying Cognitive Presence, the online STSE-based discourses were examined according to the four phases of the P.I. Model. The online discussions were measured at macro-levels to reveal patterns in student STSE-based discussions and content analysis of threaded discussions. These analyses indicated that 87% of the students participated in

  19. Partnering To Build a Quality Workforce: Critical Issues in Environmental Technology Education at Two-Year Colleges. A Report of the National Forum on Critical Issues in Environmental Technology Education at Two-Year Colleges (Washington, D.C., March 2-4, 1995).

    Science.gov (United States)

    Kabat, Ellen J.; Friedel, Janice Nahra; Senew, Mike

    The National Forum on Critical Issues in Environmental Technology Education at Two-Year Colleges addressed critical issues relevant to environmental technology education in the United States. Forty-three participants from across the country who attended the 1995 Forum represented business and industry, two-year colleges, four-year colleges and…

  20. Special Issue: Software-engineering, Properites of Language and Aspect Technologies

    DEFF Research Database (Denmark)

    Bergmans, Lodewijk; Gybels, Kris; Ernst, Erik

    2008-01-01

    of pointcuts, and the complexity of novel and innovative general-purpose pointcut languages. This paper proposes an interface for user-defined pointcuts, which allows for the definition of new, possibly domain-specific, kinds of pointcuts without extending the language. The second paper, "Developing Law......Dear Readers, SPLAT is a series of workshops held at the AOSD conference; SPLAT stands for "Software engineering Properties of Languages and Aspect Technologies". Software engineering properties, also referred to as quality or non-functional requirements, or 'ilities', describe the various...... characteristics of software beyond mere functionality. Software engineering properties, such as comprehensibility, evolvability, modularity, and analyzability, are crucial dimensions to consider in the assessment of the quality of software engineering activities and products. Generally, designers and users...

  1. Issues in the Use of Information and Communication Technologies and Unethical Behaviors: An Overview

    Directory of Open Access Journals (Sweden)

    Fatma Kübra ÇELEN1,

    2016-12-01

    Full Text Available The purpose of this study is to examine literature on unethical behavior in the use of information and communication technologies (ICT. In reaching this goal a search was conducted. When presenting the results findings of research conducted in abroad and in Turkey are presented respectively in order from the oldest to date. Findings indicated that ICT users have some dilemmas about identified ethical behavior and awareness in ethical behavior. In addition, social norms, gender, age, personal values, moral judgment, social values, moral responsibility has been effective in the ethical and legal use of ICT. On the other hand, it was confirmed that individuals’ opinions about unethical behavior in the use of ICT change according to demographic characteristics like gender, and parents’ education level in researches conducted in Turkey.

  2. Historic Buildings of the Warsaw University of Technology - Selected Issues of Renovation, Modernisation and Adaptation

    Science.gov (United States)

    Wagner, Anna Agata

    2016-06-01

    The historic buildings of the Warsaw University of Technology display not only outstanding architectural values, but are also representative of the trends in preservation, restoration, and adaptation that were prevalent at the time of their modernization. The post-war rebuilding of the WUT was more akin to modernization than reconstruction. But the freedom to shape modern architectural forms in the 1960s and '70s brought with it a lack of respect for their historic environment. A change in the approach to historic buildings and their integration with modern architecture came in the late 1970s. The most recent modernization of the WUT's historic buildings, especially after Poland's accession to the EU, resulted in many good examples of proper, harmonious integration between the `modern' and the `traditional'.

  3. Monitoring Employee Behavior Through the Use of Technology and Issues of Employee Privacy in America

    Directory of Open Access Journals (Sweden)

    Mahmoud Moussa

    2015-04-01

    Full Text Available Despite the historic American love for privacy that has enhanced innovation and creativity throughout the country, encroachments on privacy restrain individual freedom. Noticeable, advances in technology have offered decision makers remarkable monitoring aptitudes that can be used in numerous tasks for multiple reasons. This has led scholars and practitioners to pose a significant number of questions about what is legitimate and illegitimate in the day-to-day affairs of a business. This article is composed of (a research about electronic monitoring and privacy concerns; (b definitions of, critiques of, and alternatives to electronic performance monitoring (EPM; (c motives behind employee monitoring and leadership behaviors; (d advice that makes monitoring less distressful; (e employee monitoring policies; (f reviewing policies and procedures; (g the role of human resource development (HRD in employee assessment and development; and (h conclusion and recommendations for further studies.

  4. Historic Buildings of the Warsaw University of Technology - Selected Issues of Renovation, Modernisation and Adaptation

    Directory of Open Access Journals (Sweden)

    Wagner Anna Agata

    2016-06-01

    Full Text Available The historic buildings of the Warsaw University of Technology display not only outstanding architectural values, but are also representative of the trends in preservation, restoration, and adaptation that were prevalent at the time of their modernization. The post-war rebuilding of the WUT was more akin to modernization than reconstruction. But the freedom to shape modern architectural forms in the 1960s and ’70s brought with it a lack of respect for their historic environment. A change in the approach to historic buildings and their integration with modern architecture came in the late 1970s. The most recent modernization of the WUT’s historic buildings, especially after Poland’s accession to the EU, resulted in many good examples of proper, harmonious integration between the ‘modern’ and the ‘traditional’.

  5. Technology and economic impacts of mega-sports events: A key issue? Exploratory insights from literature

    Directory of Open Access Journals (Sweden)

    Chanaron Jean Jacques

    2014-01-01

    Full Text Available Mega-sport events such as Olympic Games or Football World Cup are always presented as providing the hosting nation and/or city with huge benefits. Supporters of such events quote economic, social and cultural impacts for the region as well as contributions to scientific and technological progress and innovation. obviously, they need to politically justify the impressive and growing financial investment required by organizing Olympic Games or World Cup. The article aims at looking at a quite abundant academic literature with the objectives of defining the various potential impacts and the methods used for their assessment. It concludes that there is no universal and scientifically valid model for evaluating the benefits of mega-sport events and that organizers should be very cautious when arguing in favor of deciding to host such events.

  6. Acceptance of wearable technology by people with Alzheimer's disease: issues and accommodations.

    Science.gov (United States)

    Mahoney, Edward L; Mahoney, Diane F

    2010-09-01

    The increasing number of cognitively impaired older adults who exhibit wandering tendencies raises safety concerns. The purpose of the current study was to research the State-of the-Art in Wearable Technologies for persons with Alzheimer's Disease and identify challenges unique to this population and lessons learned. Inclusion criteria specified systems/devices that completed laboratory testing and were commercially available for usage by community-based Alzheimer's family caregivers. Methods included a series of Internet product searches and telephone interviews with related corporate representatives and participant's referrals. Results indicated many products in development or academic research use but only a limited number were available that met the study criteria. The interviews with key informants revealed features necessary to consider when making products to be worn by persons with cognitive impairment. In conclusion, there is no ideal solution and opportunities remain for marketplace innovations and for addressing the challenges associated with balancing safety and security.

  7. North Korean nuclear issues and the LWR project; analysis of the key technologies

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Koo; Kwack, E. H.; Shin, J. S.; An, J. S.; Lee, J. U.; Kim, H. T.; Kim, J. S.; Yoon, Y. C

    2000-11-01

    Year 2000 will be remembered as an epoch making period between two Koreas. Korean nuclear industries became activated with the KEDO LWR main contracts entering into force in February, 2000. Respective design, manufacturing and construction activities are mobilized in accordance with the total project schedule of about 100 months. What started out as the nuclear power plant design standardization project in the early '80s, is now being implemented as repeat construction of KSNPs at Yonggwang and Ulchin sites as well as at Kumho site in the DPRK. However, the KEDO construction schedule and the past nuclear inconsistency issues are closely linked due to the nonproliferation concerns. In practice, the IAEA must come to the conclusion that the correctness and completeness must be fulfilled before delivery of the first key component for the KEDO LWR unit 1. While the IAEA verification process tends to focus on the nuclear materials accountancy control, longer term objective between two Koreas is bound to take the form of confidence building. It is necessary to analyse the nuclear research and production facilities in order to make proper evaluation of a nation's nuclear capabilities. Close assessment on development status of graphite moderated reactors and their operation history, spent fuel reprocessing facilities, and HEU production capabilities would be essential. In addition, illicit trafficking possibilities should be addressed. Chapter 1 describes the graphite moderated reactors in general; Chapter 2 describes various reprocessing processes and their detection capabilities; Chapter 3 contains possible uranium enrichment processes with their detection capabilities, and Chapter 4 summarizes the international treaties in illicit trafficking control with the IAEA database.

  8. A Framework for the Evaluation of Biosecurity, Commercial, Regulatory, and Scientific Impacts of Plant Viruses and Viroids Identified by NGS Technologies

    Science.gov (United States)

    Massart, Sebastien; Candresse, Thierry; Gil, José; Lacomme, Christophe; Predajna, Lukas; Ravnikar, Maja; Reynard, Jean-Sébastien; Rumbou, Artemis; Saldarelli, Pasquale; Škorić, Dijana; Vainio, Eeva J.; Valkonen, Jari P. T.; Vanderschuren, Hervé; Varveri, Christina; Wetzel, Thierry

    2017-01-01

    Recent advances in high-throughput sequencing technologies and bioinformatics have generated huge new opportunities for discovering and diagnosing plant viruses and viroids. Plant virology has undoubtedly benefited from these new methodologies, but at the same time, faces now substantial bottlenecks, namely the biological characterization of the newly discovered viruses and the analysis of their impact at the biosecurity, commercial, regulatory, and scientific levels. This paper proposes a scaled and progressive scientific framework for efficient biological characterization and risk assessment when a previously known or a new plant virus is detected by next generation sequencing (NGS) technologies. Four case studies are also presented to illustrate the need for such a framework, and to discuss the scenarios. PMID:28174561

  9. The Ethics of Instructional Technology: Issues and Coping Strategies Experienced by Professional Technologists in Design and Training Situations in Higher Education

    Science.gov (United States)

    Lin, Hong

    2007-01-01

    To correspond to the Association for Educational Communication Technology (AECT) Code of Professional Ethics and the professional journal TechTrends' ethics columns, this paper provides empirical data regarding ethical issues associated with the use of instructional technology in design and training situations. In-depth interviews of 20…

  10. Instructional Technology: Issues and Concerns. Summary Report of the Lake Okoboji Educational Media Leadership Conference (20th Lakeside Laboratory, Lake Okoboji, Milford, Iowa, August 11-16, 1974).

    Science.gov (United States)

    Cochran, Lida M.; And Others

    Participants of the twentieth Lake Okoboji Educational Media Leadership Conference examined various issues in the field of instructional technology, and suggested new directions. This report presents descriptions of general meetings and group studies. Ten subtopics were discussed: (1) humanizing education via instructional technology, (2)…

  11. Touch Interaction with 3D Geographical Visualization on Web: Selected Technological and User Issues

    Science.gov (United States)

    Herman, L.; Stachoň, Z.; Stuchlík, R.; Hladík, J.; Kubíček, P.

    2016-10-01

    The use of both 3D visualization and devices with touch displays is increasing. In this paper, we focused on the Web technologies for 3D visualization of spatial data and its interaction via touch screen gestures. At the first stage, we compared the support of touch interaction in selected JavaScript libraries on different hardware (desktop PCs with touch screens, tablets, and smartphones) and software platforms. Afterward, we realized simple empiric test (within-subject design, 6 participants, 2 simple tasks, LCD touch monitor Acer and digital terrain models as stimuli) focusing on the ability of users to solve simple spatial tasks via touch screens. An in-house testing web tool was developed and used based on JavaScript, PHP, and X3DOM languages and Hammer.js libraries. The correctness of answers, speed of users' performances, used gestures, and a simple gesture metric was recorded and analysed. Preliminary results revealed that the pan gesture is most frequently used by test participants and it is also supported by the majority of 3D libraries. Possible gesture metrics and future developments including the interpersonal differences are discussed in the conclusion.

  12. The issues that class teachers encounter during application of science and technology teaching curriculum

    Directory of Open Access Journals (Sweden)

    Mustafa Ugras

    2014-08-01

    Full Text Available This study aimed at investigating the challenges class teachers face in the curriculum implementation and whether these challenges differ in relation to teachers’ gender, level of education, department they graduated from and teaching experience. For this purpose; a questionnaire was developed by the researcher. Items of the questionnaire were selected from the related literature and validated by a group of expert in the field. A pilot study was conducted to assess the clarity of the questionnaire items. The internal reliability of the final version of questionnaire was calculated by using Cronbach’s Alpha Formula and found be high (α=0.85. The participants of this research included 342 class teachers who were teaching 4th and 5th class in 57 different elementary schools in 2010-2011 academic years in Bingol and Diayrbakir cities. The results of the survey were considered by using SPSS packet program. In the analyzing of data obtained from this study, frequency, arithmetic average, t-test and variance analysis were used. From the obtained data, it was determined that the 4th and 5th class teachers encounter different problems in science and technology teaching program, especially in performance homework, sourcing and lesson time topics.

  13. Integration of microarray technology into prenatal diagnosis: counselling issues generated during the NICHD clinical trial.

    Science.gov (United States)

    Wapner, Ronald J; Driscoll, Deborah A; Simpson, Joe Leigh

    2012-04-01

    Cytogenetic microarray analysis (CMA) in prenatal testing detects chromosome abnormalities and new genetic syndromes that would be missed by conventional cytogenetics and has the potential to significantly enhance prenatal genetic evaluation. A large Eunice Kennedy Shriver National Institute Of Child Health and Human Development (NICHD)-sponsored multicentered trial to assess the role of CMA as a primary prenatal diagnostic tool has been completed, and results will soon be available. Integration of this technology into clinical care will require thoughtful changes in patient counseling. Here, we examine four cases, all ascertained in the NICHD prenatal microarray study, to illustrate the challenges and subtleties of genetic counseling required with prenatal CMA testing. Although the specifics of each case are distinct, the underlying genetic principles of uncertainty, variable expressivity, and lack of precise genotype-phenotype correlation are well known and already part of prenatal counseling. Counselor and practitioner education will need to include both the science of interpreting array findings as well as development of improved approaches to uncertainty. A team approach to interpretation will need to be developed, as will standardized guidelines by professional organizations and laboratories. Of equal import is additional research into patient attitudes and desires, and a better understanding of the full phenotypic spectrum of copy number variants discovered in utero.

  14. Technical issues associated with innovative environmental technology: FTIR computer aided tomography

    Energy Technology Data Exchange (ETDEWEB)

    Todd, L.A. [Univ. of North Carolina, Chapel Hill, NC (United States). Dept. of Environmental Sciences and Engineering

    1995-12-31

    This research reports on a new innovation in chemical measurement technology that combines Open-path Fourier Transform Infrared (OP-FTIR) spectroscopy with computed tomography to create two-dimensional maps of air contaminants that are both spatially and temporally resolved. This method has been evaluated with numerical studies that tested different iterative reconstruction algorithms and OP-FTIR configurations. The success of this system for characterizing the flow of contaminants in air, exposure assessment, emission monitoring and leak detection, was closely linked to the choice of reconstruction algorithm and configuration. A systematic method was developed to evaluate these parameters using static and time series test maps under ideal and non-ideal sampling conditions. Concentration map quality was evaluated using qualitative and quantitative criteria. Map reconstruction quality using different algorithms configurations was found to be intimately related to the complexity of the test maps. The results of this research underscored the need to thoroughly test the system through numerical studies prior to field implementation; a wide variety of concentration maps, relevant to the application, should be tested under both ideal and non-ideal sampling conditions.

  15. Status report on energy recovery from municipal solid waste: technologies, lessons and issues. Information bulletin of the energy task force of the urban consortium

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    A review is presented of the lessons learned and issues raised regarding the recovery of energy from solid wastes. The review focuses on technologies and issues significant to currently operating energy recovery systems in the US - waterwall incineration, modular incineration, refuse derived fuels systems, landfill gas recovery systems. Chapters are: Energy Recovery and Solid Waste Disposal; Energy Recovery Systems; Lessons in Energy Recovery; Issues in Energy Recovery. Some basic conclusions are presented concerning the state of the art of energy from waste. Plants in shakedown or under construction, along with technologies in the development stages, are briefly described. Sources of additional information and a bibliography are included. (MCW)

  16. Current issues and actions

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the progress that has been made toward achieving full regulatory compliance at the Hanford Site. Ongoing compliance self-assessments, implementation of the Tri-Party Agreement, and public meetings continue to identify environmental compliance issues. These issues are discussed openly with the regulatory agencies and with the public to ensure that all environmental compliance issues are addressed.

  17. Renegotiating GM crop regulation: Targeted gene-modification technology raises new issues for the oversight of genetically modified crops

    OpenAIRE

    2011-01-01

    Targeted genetic modification, which enables scientists to genetically engineer plants more efficiently and precisely, challenges current process-based regulatory frameworks for genetically modified crops.

  18. Engaging Students in Modeling as an Epistemic Practice of Science: An Introduction to the Special Issue of the Journal of Science Education and Technology

    Science.gov (United States)

    Campbell, Todd; Oh, Phil Seok

    2015-04-01

    This article provides an introduction for the special issue of the Journal of Science Education and Technology focused on science teaching and learning with models. The article provides initial framing for questions that guided the special issue. Additionally, based on our careful review of each of these articles, some discussion of how selected articles within the issue informed these questions. Specifically, when considering key facets of modeling instruction or design features of modeling curriculum, the studies in the special issue provided insight into productive ways in which teachers engaged students in modeling practices. Further, modeling pedagogies—pedagogies for transforming scientific practices of modeling into students' experience—were reified so that how these pedagogies could be coordinated into classroom instruction was revealed. When characteristic features of students' engagement in modeling were considered, research offered insight into productive model-based learning sequences for K-6 modelers and how students' development of productive epistemologies can evolve differently. Finally, the special issue considered how technology facilitated cognitive processes and/or instructional practices by examining learners' interactions with technology within modeling contexts. In this, instructional sequences using agent-based modeling (ABM) as a central technology are shared. These include the role of ABM in scaling student-modeling experiences beyond individuals to classroom experiences and how ABM can support student investigations of complex phenomenon that is not directly observable, among other affordances. Other articles also investigated some aspects of learners' interactions with technology to inform how technology-enhanced science teaching and learning with models.

  19. Small scale wind power harnessing in Colombian oil industry facilities: Wind resource and technology issues

    Energy Technology Data Exchange (ETDEWEB)

    Giraldo, Mauricio; Nieto, Cesar; Escudero, Ana C.; Cobos, Juan C.; Delgado, Fernando

    2010-07-01

    Full text: Looking to improve its national and international standing, Colombia's national oil company, Ecopetrol, has set its goal on becoming involved on the production of energy from multiple sources, most importantly, on having an important percentage of its installed capacity from renewable sources. Part of this effort entices the evaluation of wind power potential on its facilities, including production, transportation and administrative, as well as identifying those technologies most suitable for the specific conditions of an equatorial country such as Colombia. Due to the lack of adequate site information, the first step consisted in superimposing national data to the facilities map of the company; this allowed for the selection of the first set of potential sites. From this set, the terminal at Covenas-Sucre was selected taking into account not only wind resource, but ease of access and power needs, as well as having a more or less representative wind potential in comparison to the rest of the country. A weather station was then installed to monitor wind variables. Measurements taken showed high variations in wind direction, and relatively low velocity profiles, making most commercially available wind turbines difficult to implement. In light of the above, a series of iterative steps were taken, first considering a range of individual Vertical Axis Wind Turbines (VAWT), given their capacity to adapt to changing wind directions. However, wind speed variations proved to be a challenge for individual VAWT's, i.e. Darriues turbines do not work well with low wind speeds, and Savonius turbines are not efficient of high wind speeds. As a result, a combined Darrieus- Savonius VAWT was selected given the capacity to adapt to both wind regimes, while at the same time modifying the size and shape of the blades in order to adapt to the lower average wind speeds present at the site. The resulting prototype is currently under construction and is scheduled to

  20. 物联网技术及安全问题%Technology and Security Issues of Internet of Things

    Institute of Scientific and Technical Information of China (English)

    朱新良

    2015-01-01

    物联网被称为继计算机和互联网之后的第三次信息技术革命,其应用无处不在,而物联网的安全问题直接关系到它的广泛应用。从物联网的安全构架和特点出发,阐述了物联网三层体系结构中存在的安全问题,提出了解决方案和涉及到的关键技术,对感知层的安全措施进行了具体的阐述,包括密钥管理算法、安全路由协议、数据融合技术以及身份认证和访问控制,等等。最后介绍了物联网的典型应用和发展前景。%Internet of things is called the third IT revolution following the computer and the internet, and now it is everywhere.The security issues of the Internet of Things (IoT)are directly related to the wide application of its system.Beginning with introducing the architecture and features of IoT security,this paper expounds several security issues of IoT that exist in the three-layer system structure,and comes up with solutions coupled with key technologies involved.Among these safety measures concerned,those in perception layer are particularly elaborated,including key management and algorithm,security routing protocol,data fusion technology,as well as authentication and access control,etc.The paper also presents the typical application and future prospect of the internet of things.

  1. Smart homes, private homes? An empirical study of technology researchers' perceptions of ethical issues in developing smart-home health technologies.

    Science.gov (United States)

    Birchley, Giles; Huxtable, Richard; Murtagh, Madeleine; Ter Meulen, Ruud; Flach, Peter; Gooberman-Hill, Rachael

    2017-04-04

    Smart-home technologies, comprising environmental sensors, wearables and video are attracting interest in home healthcare delivery. Development of such technology is usually justified on the basis of the technology's potential to increase the autonomy of people living with long-term conditions. Studies of the ethics of smart-homes raise concerns about privacy, consent, social isolation and equity of access. Few studies have investigated the ethical perspectives of smart-home engineers themselves. By exploring the views of engineering researchers in a large smart-home project, we sought to contribute to dialogue between ethics and the engineering community. Either face-to-face or using Skype, we conducted in-depth qualitative interviews with 20 early- and mid-career smart-home researchers from a multi-centre smart-home project, who were asked to describe their own experience and to reflect more broadly about ethical considerations that relate to smart-home design. With participants' consent, interviews were audio-recorded, transcribed and analysed using a thematic approach. Two overarching themes emerged: in 'Privacy', researchers indicated that they paid close attention to negative consequences of potential unauthorised information sharing in their current work. However, when discussing broader issues in smart-home design beyond the confines of their immediate project, researchers considered physical privacy to a lesser extent, even though physical privacy may manifest in emotive concerns about being watched or monitored. In 'Choice', researchers indicated they often saw provision of choice to end-users as a solution to ethical dilemmas. While researchers indicated that choices of end-users may need to be restricted for technological reasons, ethical standpoints that restrict choice were usually assumed and embedded in design. The tractability of informational privacy may explain the greater attention that is paid to it. However, concerns about physical privacy may

  2. NGNP Project Regulatory Gap Analysis for Modular HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    Wayne Moe

    2011-09-01

    The Next Generation Nuclear Plant (NGNP) Project Regulatory Gap Analysis (RGA) for High Temperature Gas-Cooled Reactors (HTGR) was conducted to evaluate existing regulatory requirements and guidance against the design characteristics specific to a generic modular HTGR. This final report presents results and identifies regulatory gaps concerning current Nuclear Regulatory Commission (NRC) licensing requirements that apply to the modular HTGR design concept. This report contains appendices that highlight important HTGR licensing issues that were found during the RGA study. The information contained in this report will be used to further efforts in reconciling HTGR-related gaps in the NRC licensing structure, which has to date largely focused on light water reactor technology.

  3. 对监管现场防控模式问题的思考%Thinking About the Issue of the Regulatory Site Control Mode

    Institute of Scientific and Technical Information of China (English)

    戴荣法

    2011-01-01

    监狱安全在监狱全局工作中居首要地位。罪犯现场防控必须要遵循一定的原则;其防控模式以"五大防控系统"为基本框架,以"五大重点"为罪犯现场防控的关键点,以全面落实"四大禁止措施"为监管现场防控的着力点,以民警直接管理主导罪犯现场全程管控为重要手段,以发现异常、有效处置为罪犯现场防控的核心要求。目前,现行罪犯现场防控工作存在缺陷需要创新监管措施。%The safety of the prison plays the primary, role in the overall prison work. The criminal regulatory site control must obey certain principle and its' mode is based on tile "Five Control Systems" . We should focus on the crime spot control, which means the key point is "the five key points" ; and we should take the "Four Forbidden Measures" as the focal point. The prison police should take directly management of the criminal spot, and use the full control as the important mean, and it is the nuclear requirement of the criminal spot dealt effectively. At present, the prevention and control of crime scene have defect and need creative regulatory measures.

  4. EARLY EVALUATION OF NEW HEALTH TECHNOLOGIES: THE CASE FOR PREMARKET STUDIES THAT HARMONIZE REGULATORY AND COVERAGE PERSPECTIVES.

    Science.gov (United States)

    Levin, Leslie

    2015-01-01

    With an increasing awareness that active engagement between policy decision makers, HTA agencies, regulators and payers with industry in the premarket space is needed, a disruptive comprehensive approach is described which moves the evidentiary process exclusively into this space. Single harmonized studies pre-market to address regulatory and coverage needs and expectations are more likely to be efficient and less costly and position evidence to drive rather than test innovation. An example of such a process through the MaRS EXCITE program in Ontario, Canada, now undergoing proof of concept, is briefly discussed. Other examples of dialogue between decision makers and industry pre-market are provided though these are less robust than a comprehensive evidentiary approach.

  5. GLOBALIZATION, INFORMATION AND COMMUNICATION TECHNOLOGIES (ICTs AND OPEN/DISTANCE LEARNING IN NIGERIA: Trends, Issues and Solution

    Directory of Open Access Journals (Sweden)

    Akande Joshua OLUSOLA

    2011-07-01

    Full Text Available The main thrust of this paper is to discuss the development of open and distance education in Nigeria and the major manifestations of the use of information and communication technologies (ICTs in education in open and distance learning. This study further discusses the importance and use of ICTs in open and distance learning in making education accessible to a larger population of students. From that vantage point this paper reviews the phenomenon of ICTs in open and distance learning in developing countries such as Nigeria. The paper identifies a number of issues that impede the effective optimization of ICTs in open and distance learning in developing countries. Prominent among the issues highlighted are poverty, intermittent supply of electricity and language barrier. The paper argues that these problems are to be tackled if the objective of enhancing the potentials of ICTs in open and distance learning in developing countries were to be achieved. On that note the current paper makes some humble suggestions on how to curtail the problems. The study employed descriptive method. An intact class of students that registered for the Bachelor of Education distance learning programme of the Faculty of Education of the Obafemi Awolowo University,Ile-Ife formed the samples used for the study. This was done to collect information on the factors affecting usage of ICT. The result shows that lack of skills rank highest (46.1%, following this is non availability of ICT at home (18.8%, costs (11.3% and non familiarity with ICT (10.6%.

  6. Implications of Convergence on the Regulatory Regime, e-Commerce, the Industry, and the Society at large in South Africa

    OpenAIRE

    Mlitwa, Nhlanhla Boyfriend

    2004-01-01

    Convergence in information communication technology is about real issues of technological innovations and change. It encompasses a combination of benefits and challenges, not only for the market, the industry, or technology sectors, but also for the regulatory regime and the society at large. Technology convergence offers massive opportunities for the development of new services and the expansion of consumer choice. It certainly expands the overall information market, and is the catalyst f...

  7. IEA Wind Task 23, offshore wind technology and deployment. Subtask 1: Experience with critical deployment issues. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Lemming, J.

    2010-10-15

    The final report for IEA Wind Task 23, Offshore Wind Energy Technology and Deployment, is made up of two separate reports: Subtask 1: Experience with Critical Deployment Issues and Subtask 2: Offshore Code Comparison Collaborative (OC3). The Subtask 1 report included here provides background information and objectives of Task 23. It specifically discusses ecological issues and regulation, electrical system integration and offshore wind, external conditions, and key conclusions for Subtask 1. A comprehensive approach to planning is needed that integrates impacts on ecology, the effects of electrical infrastructure, and the layout of wind farms. Governments, which usually finance ecological research, should disclose results for wide dissemination as they become available. As example the workshop held suggested that documents covering the issues like offshore wind energy legislation, Guidelines for EIAs and SEAs and best practices need to be produced and distributed on a regular basis, as ecological research progresses and experience from the planning and operation of existing wind farms emerges. Research should help strike the balance between optimum regulation and the need to get projects up and running. Such research is needed to increase understanding of offshore wind metrology and its impact on electrical power fluctuations. More work is needed to develop special grid code and standards for offshore. The transient behavior of large cable installations (switching / harmonic/ Behavior and modeling of large HV cable systems) must be better understood. Connection and control systems must be developed for large offshore wind farms. Work is needed to develop the technical architecture of offshore wind grid systems. Public access to measurements (e.g., turbine power output, meteorological masts, buoys) is important, especially for model validation. Determining wake effects is currently the most important challenge in wind engineering. Emphasis should be put into

  8. Carbon Capture and Storage Legal and Regulatory Review. Edition 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The International Energy Agency (IEA) estimates that 100 carbon capture and storage (CCS) projects must be implemented by 2020 and over 3000 by 2050 if CCS is to fully contribute to the least-cost technology portfolio for CO2 mitigation. To help countries address the many legal and regulatory issues associated with such rapid deployment, the IEA launched the Carbon Capture and Storage Legal and Regulatory Review (CCS Review) in October 2010. The CCS Review gathers contributions by national and regional governments, as well as leading organisations engaged in CCS regulatory activities, to provide a knowledge-sharing forum that supports national-level CCS regulatory development. Each contribution provides a short summary of recent and anticipated developments and highlights a particular regulatory theme (such as financial contributions to long-term stewardship). To introduce each edition, the IEA provides a brief analysis of key advances and trends. Produced bi-annually, the CCS Review provides an up-to-date snapshot of global CCS regulatory developments. The theme for the second edition of the CCS Review, released in May 2011, is long-term liability for stored CO2. Other key issues addressed include: national progress towards implementation of the EU CCS Directive; developments in marine treaties relevant to CCS; international climate change negotiations; and the development process for CCS regulation.

  9. Survey on the technological development issues for large-scale methanol engine power generation plant; Ogata methanol engine hatsuden plant ni kansuru gijutsu kaihatsu kadai chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Based on the result of `Survey on the feasibility of large-scale methanol engine power generation plant` in fiscal 1992, concrete technological development issues were studied for its practical use, and the technological R & D scheme was prepared for large-scale methanol engine power plant featured by low NOx and high efficiency. Technological development issues of this plant were as follows: improvement of thermal efficiency, reduction of NOx emission, improvement of the reliability and durability of ignition and fuel injection systems, and reduction of vibration. As the economical effect of the technological development, the profitability of NOx control measures was compared between this methanol engine and conventional heavy oil diesel engines or gas engines. As a result, this engine was more economical than conventional engines. It was suggested that development of the equipment will be completed in nearly 4 years through every component study, single-cylinder model experiment and real engine test. 21 refs., 43 figs., 19 tabs.

  10. 78 FR 30384 - Federal Regulatory Enforcement Fairness Hearing; Region X Regulatory Fairness Board

    Science.gov (United States)

    2013-05-22

    ... ADMINISTRATION Federal Regulatory Enforcement Fairness Hearing; Region X Regulatory Fairness Board AGENCY: U.S... Business Regulatory Fairness Board. SUMMARY: The (SBA) Office of the National Ombudsman is issuing this notice to announce the location, date and time of the Regional Small Business Regulatory Fairness hearing...

  11. 78 FR 36011 - Region VII Regulatory Fairness Board; Federal Regulatory Enforcement Fairness Hearing

    Science.gov (United States)

    2013-06-14

    ... ADMINISTRATION Region VII Regulatory Fairness Board; Federal Regulatory Enforcement Fairness Hearing AGENCY: U.S... Business Regulatory Fairness Board. SUMMARY: The (SBA) Office of the National Ombudsman is issuing this notice to announce the location, date and time of the Regional Small Business Regulatory Fairness hearing...

  12. Disaster Mental Health and Positive Psychology-Considering the Context of Natural and Technological Disasters: An Introduction to the Special Issue.

    Science.gov (United States)

    Schulenberg, Stefan E

    2016-12-01

    This article serves as an introduction to the Journal of Clinical Psychology's special issue on disaster mental health and positive psychology. The special issue comprises two sections. The first section presents a series of data-driven articles and research-informed reviews examining meaning and resilience in the context of natural and technological disasters. The second section presents key topics in the area of disaster mental health, with particular relevance for positive psychology and related frameworks. The special issue is intended to bridge the gap between these two areas of applied science, with the audience being experienced clinicians or clinicians in training.

  13. Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies

    Science.gov (United States)

    Deeb, Wissam; Giordano, James J.; Rossi, Peter J.; Mogilner, Alon Y.; Gunduz, Aysegul; Judy, Jack W.; Klassen, Bryan T.; Butson, Christopher R.; Van Horne, Craig; Deny, Damiaan; Dougherty, Darin D.; Rowell, David; Gerhardt, Greg A.; Smith, Gwenn S.; Ponce, Francisco A.; Walker, Harrison C.; Bronte-Stewart, Helen M.; Mayberg, Helen S.; Chizeck, Howard J.; Langevin, Jean-Philippe; Volkmann, Jens; Ostrem, Jill L.; Shute, Jonathan B.; Jimenez-Shahed, Joohi; Foote, Kelly D.; Wagle Shukla, Aparna; Rossi, Marvin A.; Oh, Michael; Pourfar, Michael; Rosenberg, Paul B.; Silburn, Peter A.; de Hemptine, Coralie; Starr, Philip A.; Denison, Timothy; Akbar, Umer; Grill, Warren M.; Okun, Michael S.

    2016-01-01

    This paper provides an overview of current progress in the technological advances and the use of deep brain stimulation (DBS) to treat neurological and neuropsychiatric disorders, as presented by participants of the Fourth Annual DBS Think Tank, which was convened in March 2016 in conjunction with the Center for Movement Disorders and Neurorestoration at the University of Florida, Gainesveille FL, USA. The Think Tank discussions first focused on policy and advocacy in DBS research and clinical practice, formation of registries, and issues involving the use of DBS in the treatment of Tourette Syndrome. Next, advances in the use of neuroimaging and electrochemical markers to enhance DBS specificity were addressed. Updates on ongoing use and developments of DBS for the treatment of Parkinson's disease, essential tremor, Alzheimer's disease, depression, post-traumatic stress disorder, obesity, addiction were presented, and progress toward innovation(s) in closed-loop applications were discussed. Each section of these proceedings provides updates and highlights of new information as presented at this year's international Think Tank, with a view toward current and near future advancement of the field. PMID:27920671

  14. Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies.

    Science.gov (United States)

    Deeb, Wissam; Giordano, James J; Rossi, Peter J; Mogilner, Alon Y; Gunduz, Aysegul; Judy, Jack W; Klassen, Bryan T; Butson, Christopher R; Van Horne, Craig; Deny, Damiaan; Dougherty, Darin D; Rowell, David; Gerhardt, Greg A; Smith, Gwenn S; Ponce, Francisco A; Walker, Harrison C; Bronte-Stewart, Helen M; Mayberg, Helen S; Chizeck, Howard J; Langevin, Jean-Philippe; Volkmann, Jens; Ostrem, Jill L; Shute, Jonathan B; Jimenez-Shahed, Joohi; Foote, Kelly D; Wagle Shukla, Aparna; Rossi, Marvin A; Oh, Michael; Pourfar, Michael; Rosenberg, Paul B; Silburn, Peter A; de Hemptine, Coralie; Starr, Philip A; Denison, Timothy; Akbar, Umer; Grill, Warren M; Okun, Michael S

    2016-01-01

    This paper provides an overview of current progress in the technological advances and the use of deep brain stimulation (DBS) to treat neurological and neuropsychiatric disorders, as presented by participants of the Fourth Annual DBS Think Tank, which was convened in March 2016 in conjunction with the Center for Movement Disorders and Neurorestoration at the University of Florida, Gainesveille FL, USA. The Think Tank discussions first focused on policy and advocacy in DBS research and clinical practice, formation of registries, and issues involving the use of DBS in the treatment of Tourette Syndrome. Next, advances in the use of neuroimaging and electrochemical markers to enhance DBS specificity were addressed. Updates on ongoing use and developments of DBS for the treatment of Parkinson's disease, essential tremor, Alzheimer's disease, depression, post-traumatic stress disorder, obesity, addiction were presented, and progress toward innovation(s) in closed-loop applications were discussed. Each section of these proceedings provides updates and highlights of new information as presented at this year's international Think Tank, with a view toward current and near future advancement of the field.

  15. Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank - A Review of Emerging Issues and Technologies

    Directory of Open Access Journals (Sweden)

    Wissam Deeb

    2016-11-01

    Full Text Available This paper provides an overview of current progress in the technological advances and the use of deep brain stimulation (DBS to treat neurological and neuropsychiatric disorders, as presented by participants of the Fourth Annual Deep Brain Stimulation Think Tank, which was convened in March 2016 in conjunction with the Center for Movement Disorders and Neurorestoration at the University of Florida, Gainesveille FL, USA. The Think Tank discussions first focused on policy and advocacy in DBS research and clinical practice, formation of registries, and issues involving the use of DBS in the treatment of Tourette Syndrome. Next, advances in the use of neuroimaging and electrochemical markers to enhance DBS specificity were addressed. Updates on ongoing use and developments of DBS for the treatment of Parkinson’s disease, essential tremor, Alzheimer’s disease, depression, post-traumatic stress disorder, obesity, addiction were presented, and progress toward innovation(s in closed-loop applications were discussed. Each section of these proceedings provides updates and highlights of new information as presented at this year’s international Think Tank, with a view toward current and near future advancement of the field.

  16. European Framework for the Diffusion of Biogas Uses: Emerging Technologies, Acceptance, Incentive Strategies, and Institutional-Regulatory Support

    Directory of Open Access Journals (Sweden)

    Andrea G. Capodaglio

    2016-03-01

    Full Text Available Biogas will constitute a significant fraction of future power supply, since it is expected to contribute a large share of the EU renewable energy targets. Biogas, once produced, can be combusted in traditional boilers to provide heat, or to generate electricity. It can be used for the production of chemical compounds, or fed into a pipeline. This review paper will briefly analyze the current most promising emerging biogas technologies in the perspective of their potential uses, environmental benefits, and public acceptance; draw a picture of current conditions on the adoption of a biogas road map in the several EU Member States; analyze incentive and support policy implementation status and gaps; discuss non-technological barriers; and summarize proposed solutions to widen this energy’s use.

  17. Education Offered Via Telecommunications: Trends, Issues, and State-Level Problems in Instructional Technology for Colleges and Universities. Report 87-49.

    Science.gov (United States)

    California State Postsecondary Education Commission, Sacramento.

    Issues concerning telecommunications courses offered by California universities and colleges are reviewed with a focus on the progress made over the past 6 years regarding the lack of incentives for faculty to use instructional technology in their teaching, lack of coordination among interested institutions and agencies, and high initial costs for…

  18. Report on Disclosure Issues Related to the Use of Copy Control and Digital Rights Management Technologies. OECD Digital Economy Papers, No. 115

    Science.gov (United States)

    OECD Publishing (NJ1), 2006

    2006-01-01

    This report analyses the disclosure issues raised by technically-imposed restrictions on the use of digital content. It focuses on the application of copy control and digital rights management technologies in three areas: copy-protected CDs; online music, and DVD regional coding. In each of these areas, the report examines the kinds of…

  19. Epistemological and Methodological Issues for the Conceptualization, Development, and Assessment of ICT-TPCK: Advances in Technological Pedagogical Content Knowledge (TPCK)

    Science.gov (United States)

    Angeli, Charoula; Valanides, Nicos

    2009-01-01

    In this paper, several issues regarding the epistemology of technological pedagogical content knowledge (TPCK) are first raised for the purpose of clarifying the construct. Specifically, the transformative and integrative views are juxtaposed for exploring the epistemology of TPCK, and, at the end, the transformative view is adopted concluding…

  20. Research on P2P Lending Model and Regulatory Issues%我国P2P借贷模式及其监管问题研究

    Institute of Scientific and Technical Information of China (English)

    孙学立

    2014-01-01

    由于我国对金融业的改革开放相对其他产业存在某种程度的保守,金融抑制,金融资源配置不合理等现象在很大领域内普遍存在,以致难以发挥金融作为经济发展转型的润滑剂推动器作用。当前,一方面,急需资金的广大中小微企业和个体经营工商业户难以从国有大型金融机构获得金融支持;另一方面,我国出现了大量拥有闲置资金需要出借的中产富裕阶层。因此,作为金融中介,连结资金需求和供给双方的个人与个人之间借贷(P2P)民间金融机构就出现了。本文通过梳理归纳目前国内几种主流P2P借贷平台运营模式,从多角度提出对其将来更加规范科学合理发展的监管建议。%Since the reform and opening of China's financial sector relative to other industries exist to some extent conservative, financial repression, irrational allocation of financial resources and other phenomena in a large common areas, making it difficult to play the role of financial lubricant pusher transformation of economic development . Currently, on the one hand, micro-needed funds for medium and small enterprises and self-employed industrial and commercial households is difficult to obtain financial support from the large state-owned financial institutions; hand, China appears to have a lot of idle funds needed to lend affluent middle class. Therefore, as financial intermediaries, lending (P2P) links between the individual and the individual financial needs of both supply and private financial institutions have emerged. This article is currently combing through induction of several major domestic P2P lending platform business model, its future regulatory proposals put forward rational development of more standardized science from multiple perspectives.

  1. Papers on the nuclear regulatory dilemma

    Energy Technology Data Exchange (ETDEWEB)

    Barkenbus, J.N.; Freeman, S.D.; Weinberg, A.M.

    1985-10-01

    The four papers contained in this report are titled: (1) From Prescriptive to Performance-Based Regulation of Nuclear Power; (2) Nuclear Regulatory Reform: A Technology-Forcing Approach; (3) Improving the Regulation of Nuclear Power; and (4) Science and Its Limits: The Regulators' Dilemma. These four papers investigate issues relating to the long-term regulation of nuclear energy. They were prepared as part of the Institute for Energy Analysis' project on Nuclear Regulation funded by a grant from the Mellon Foundation and a smaller grant by the MacArthur Foundation. Originally this work was to be supplemented by contributions from the Nuclear Regulatory Commission and from the Department of Energy. These contributions were not forthcoming, and as a result the scope of our investigations was more restricted than we had originally planned.

  2. Trends and Issues in Technology Education Research in Taiwan: A Co-Word Analysis of 1994-2013 Graduate Theses

    Science.gov (United States)

    Lee, Lung-Sheng; Fang, Yu-Shen

    2015-01-01

    In Taiwan, the Technology Education for 1-12 graders is comprised of two courses--Living Technology (LT) and Information Technology (IT). With its ever-changing feature, Technology Education needs on-going research to support its decisions and actions. The education-related academic programs in universities regularly concern about the development…

  3. Ethical and regulatory aspects of genome editing.

    Science.gov (United States)

    Kohn, Donald B; Porteus, Matthew H; Scharenberg, Andrew M

    2016-05-26

    Gene editing is a rapidly developing area of biotechnology in which the nucleotide sequence of the genome of living cells is precisely changed. The use of genome-editing technologies to modify various types of blood cells, including hematopoietic stem cells, has emerged as an important field of therapeutic development for hematopoietic disease. Although these technologies offer the potential for generation of transformative therapies for patients suffering from myriad disorders of hematopoiesis, their application for therapeutic modification of primary human cells is still in its infancy. Consequently, development of ethical and regulatory frameworks that ensure their safe and effective use is an increasingly important consideration. Here, we review a number of issues that have the potential to impact the clinical implementation of genome-editing technologies, and suggest paths forward for resolving them such that new therapies can be safely and rapidly translated to the clinic. © 2016 by The American Society of Hematology.

  4. Impact of human genome initiative-derived technology on genetic testing, screening and counseling: Cultural, ethical and legal issues

    Energy Technology Data Exchange (ETDEWEB)

    Trottier, R.W.; Hodgin, F.C.; Imara, M.; Phoenix, D.; Lybrook, S. (Morehouse Coll., Atlanta, GA (United States). School of Medicine); Crandall, L.A.; Moseley, R.E.; Armotrading, D. (Florida Univ., Gainesville, FL (United States). Coll. of Medicine)

    1993-01-01

    Genetic medical services provided by the Georgia Division of Public Health in two northern and two central districts are compared to services provided in a district in which a tertiary care facility is located. Genetics outreach public health nurses play key roles in Georgia's system of Children's Health Services Genetics Program, including significant roles as counselors and information sources on special needs social services and support organizations. Unique features of individual health districts, (e.g., the changing face of some rural communities in ethnocultural diversity and socioeconomic character), present new challenges to current and future genetics services delivery. Preparedness as to educational needs of both health professionals and the lay population is of foremost concern in light of the ever expanding knowledge and technology in medical genetics. Perspectives on genetics and an overview of services offered by a local private sector counselor are included for comparison to state supported services. The nature of the interactions which transpire between private and public genetic services resources in Georgia will be described. A special focus of this research includes issues associated with sickle cell disease newborn screening service delivery process in Georgia, with particular attention paid to patient follow-up and transition to primary care. Of particular interest to this focus is the problem of loss to follow-up in the current system. Critical factors in education and counseling of sickle cell patients and the expectations of expanding roles of primary care physicians are discussed. The Florida approach to the delivery of genetic services contrasts to the Georgia model by placing more emphasis on a consultant-specialist team approach.

  5. Rationales for regulatory activity

    Energy Technology Data Exchange (ETDEWEB)

    Perhac, R.M. [Univ. of Tennessee, Knoxville, TN (United States)

    1997-02-01

    The author provides an outline which touches on the types of concerns about risk evaluation which are addressed in the process of establishing regulatory guides. Broadly he says regulatory activity serves three broad constituents: (1) Paternalism (private risk); (2) Promotion of social welfare (public risks); (3) Protection of individual rights (public risks). He then discusses some of the major issues encountered in reaching a decision on what is an acceptable level of risk within each of these areas, and how one establishes such a level.

  6. Carbon Capture and Storage Legal and Regulatory Review. Edition 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The International Energy Agency (IEA) considers carbon capture and storage (CCS) a crucial part of worldwide efforts to limit global warming by reducing greenhouse-gas emissions. The IEA estimates that emissions can be reduced to a level consistent with a 2°C global temperature increase through the broad deployment of low-carbon energy technologies – and that CCS would contribute about one-fifth of emission reductions in this scenario. Achieving this level of deployment will require that regulatory frameworks – or rather a lack thereof – do not unnecessarily impede environmentally safe demonstration and deployment of CCS, so in October 2010 the IEA launched the IEA Carbon Capture and Storage Legal and Regulatory Review. The CCS Review is a regular review of CCS regulatory progress worldwide. Produced annually, it collates contributions by national and regional governments, as well as leading organisations engaged in CCS regulatory activities, to provide a knowledge-sharing forum to support CCS framework development. Each two page contribution provides a short summary of recent and anticipated CCS regulatory developments and highlights a particular, pre-nominated regulatory theme. To introduce each edition, the IEA provides a brief analysis of key advances and trends, based on the contributions submitted. The theme for this third edition is stakeholder engagement in the development of CO2 storage projects. Other issues addressed include: regulating CO2-EOR, CCS and CO2-EOR for storage; CCS incentive policy; key, substantive issues being addressed by jurisdictions taking steps to finalise CCS regulatory framework development; and CCS legal and regulatory developments in the context of the Clean Energy Ministerial Carbon Capture, Use and Storage Action Group.

  7. On the Regulatory of Network of Freedom of Speech Issues%我国网络言论自由规制问题初探

    Institute of Scientific and Technical Information of China (English)

    陈小芹

    2011-01-01

    从1994年正式接入互联网至今,我国互联网发展迅速,已成为人们获取各类信息和发表言论的重要途径。在网络技术不断发展的背景下,我国通过法律划定了网络言论的边界,网络言论的法律规制不但没有扼杀言论自由,反而成为网络言论自由健康发展的有力保障。当然,我国的网络言论的法律规制也存在着一定的问题,对此,笔者提出了一些思考和建议。%From the official access to the Internet since 1994, the rapid development of China's Internet has become for all kinds of information and an important way of speech. In the background of the continuous development of network technology, our country def

  8. Canadian entrepreneur looks to Utah oil sands : possible hurdles include gaining acceptance for a new technology, funding and regulatory approval

    Energy Technology Data Exchange (ETDEWEB)

    Diekmeyer, P.

    2010-09-15

    Alberta-based Earth Energy Resources has chosen Utah for its first major oilsand development project. Utah has excellent oil sands resources, but most cannot be economically extracted using conventional methods. The president of Earth Energy Resources has proposed to use new technologies, processes and workflow methods to make resource extraction economically viable. The company currently holds a 100 percent interest in 3,170 hectares under lease from the State of Utah School and Institutional Trust Lands Administration (SITLA) in the PR Spring deposit. The recoverable high-quality bitumen is estimated at 250 million barrels. The oil sands in Utah are disaggregated and spread out over a relatively wide area. The bitumen quality is very similar to that found in the Athabasca deposit, but it has a much lower sulphur content. Earth Energy Resources plans on using the Ophus Process which involves a series of small 2,000 barrel per day production facilities that can be easily set up, and moved as the resources in one particular area are recovered. Production could be expanded as needed by the addition of more facilities. An environmentally sound citrus-based extraction chemical will replace much of the mechanical energy and caustic soda mixture used in the Clark Process. The new energy and water efficient process will significantly reduce the quantity of middlings produced in the process, thereby eliminating the need for tailings ponds and reducing environmental impacts. 1 fig.

  9. 77 FR 10351 - Regulatory Review Plan

    Science.gov (United States)

    2012-02-22

    ... XII Regulatory Review Plan AGENCY: Federal Housing Finance Agency. ACTION: Notice of final regulatory review plan. SUMMARY: The Federal Housing Finance Agency (FHFA) is issuing a notice of the final FHFA regulatory review plan for review of existing regulations under Executive Order 13579, ``Regulation...

  10. PROACTIVE REGULATORY INTERVENTION IN EU COMMUNICATIONS SECTOR AND ITS FORESEEABLE FUTURE

    Directory of Open Access Journals (Sweden)

    Mantas Barčys

    2013-06-01

    Full Text Available Purpose – to review and provide insights on the issues concerning ex ante regulatory approach in EU telecommunications (hereinafter – electronic communications industry, identify and emphasise benefits, main challenges and further regulatory prospective. Design/methodology/approach – based on current regulatory framework and analysis of academic literature, author discusses problematic issues related to the needs and further perspectives of proactive regulatory regime in EU electronic communications sector. Findings – the author reviews special qualities for different regulatory regimes (ex ante, ex post and examines them in the context of sharp developments of the industry and EU regulatory policy. Research limitations/implications –the analysis aims to convey the main understanding on the regulatory specifics of the communications industry, the main features, distinguishing communications industry from the others and foreseeable regulatory perspectives Practical implications – the core aspect of the paper is to evaluate current regulatory approach of the EU electronic communications sector and assess potential regulatory approaches in the context of making self-sustaining pro-competitive market structure, technological development. Originality/Value – the paper highlights some significant changes between two regulatory approaches in the light of specific features in EU electronic communications. Author provides his insights on the status and perspectives on application for both regulatory methods. Apparently, these issues have so far been subjected too little academic analysis. As shown in this paper, regulatory policy can have the essential impact on the activities taken by other players. The decision to give an even bigger role to competition rules, do not mean to eliminate sector specifics itself. With this in mind, EU legislators are not able to eliminate proactive regulatory control, thus reducing ex ante rules progressively

  11. Steam Generator tube integrity -- US Nuclear Regulatory Commission perspective

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, E.L.; Sullivan, E.J.

    1997-02-01

    In the US, the current regulatory framework was developed in the 1970s when general wall thinning was the dominant degradation mechanism; and, as a result of changes in the forms of degradation being observed and improvements in inspection and tube repair technology, the regulatory framework needs to be updated. Operating experience indicates that the current U.S. requirements should be more stringent in some areas, while in other areas they are overly conservative. To date, this situation has been dealt with on a plant-specific basis in the US. However, the NRC staff is now developing a proposed steam generator rule as a generic framework for ensuring that the steam generator tubes are capable of performing their intended safety functions. This paper discusses the current U.S. regulatory framework for assuring steam generator (SG) tube integrity, the need to update this regulatory framework, the objectives of the new proposed rule, the US Nuclear Regulatory Commission (NRC) regulatory guide (RG) that will accompany the rule, how risk considerations affect the development of the new rule, and some outstanding issues relating to the rule that the NRC is still dealing with.

  12. An Examination of Information Technology and Its Perceived Quality Issues in Single System Hospitals in the United States

    Science.gov (United States)

    Byrd, Linda W.

    2009-01-01

    The safety and quality of healthcare is of great concern in the United States. The positive effects of information technology reported in past research, especially case studies, has encouraged expectations that information technology may increase the quality of healthcare while reducing costs of healthcare. The goals of this study was to examine…

  13. Emerging issues and current trends in assistive technology use 2007-2010: practising, assisting and enabling learning for all.

    Science.gov (United States)

    Abbott, Chris; Brown, David; Evett, Lindsay; Standen, Penny

    2014-11-01

    Following an earlier review in 2007, a further review of the academic literature relating to the uses of assistive technology (AT) by children and young people was completed, covering the period 2007-2011. As in the earlier review, a tripartite taxonomy: technology uses to train or practise, technology uses to assist learning and technology uses to enable learning, was used in order to structure the findings. The key markers for research in this field and during these three years were user involvement, AT on mobile mainstream devices, the visibility of AT, technology for interaction and collaboration, new and developing interfaces and inclusive design principles. The paper concludes by locating these developments within the broader framework of the Digital Divide.

  14. A global perspective on electronic cigarette’s future development and related controversial and regulatory issues%全球电子烟市场发展、主要争议及政府管制

    Institute of Scientific and Technical Information of China (English)

    李保江

    2014-01-01

    The development trend and related controversial and regulatory issues of electronic cigarette were reviewed on a global perspective. Regulation in accordance with China’s national conditions was proposed, i.e. e-cigarette should be regulated as tobacco products in China. Its standardized and scientific development must comply with either of the existing four types of regulation measures, namely strict prohibition, regulated as medicinal products, as tobacco products and as consumer goods.%论述了全球电子烟市场发展趋势,以及由电子烟引发的争议;针对各国政府对电子烟管制的现状,即严格禁止、纳入药品管制、纳入烟草制品管制或作为消费品监管四种类型,分析了电子烟管制的趋向,提出了我国加强电子烟管制的可行方案:立足我国国情和电子烟市场发展实际,把电子烟纳入烟草制品进行管制,促进我国电子烟市场早日走上法治化、规范化、科学化发展轨道。

  15. Increased susceptibility to the innovative energy-saving technologies in the oil and fat industry by improving regulatory and institutional framework

    Directory of Open Access Journals (Sweden)

    V.G. Dyuzhev

    2014-09-01

    Full Text Available The aim of the article. The aim of the article is to increase the susceptibility to innovative energy saving technologies in oil and fat industry basing on the formation of organizational and economic section of the regulatory framework of energy efficiency programs. The results of the analysis. Angle susceptibility innovative energy conservation program in the oilseed industry is analyzed in this article. Stages of formation of the organizational and economic section sectoral energy saving program to improve the level of susceptibility to specific innovative energy-saving technologies are developed. Step 1. To conduct classification measures in the oil and fat industry by: structural and institutional facilities; types of energy savings; the level of expenses; typical beneficial effects. Step 2. Analysis of information flows from various sources on the problems of energy saving based on the use of energy-saving measures in terms of enterprise in oil and fat industries. Step 3. This step is based on the analysis and systematization of information flows (step 2, and in accordance with the classification criteria (stage 1 were isolated most current energy-saving areas, grouped by objects oil and fat industry, marked specificity processes, respectively, each object has their «targeted» energy efficiency measures. Received results of the group of energy-saving measures after the «address» information flow is an important element in the formation of secondary innovation susceptibility to energy conservation. Step 4. Forming a typical list of possible effects of energy-saving measures for implementation at different sites. Step 5. Combination of typical beneficial effects of specific measures will show the potential effects that are possible as a result of energy conservation on specific sites for specific fuel and energy resources, in particular the level of capital expenditures. It is necessary to improve the innovative capabilities of

  16. 76 FR 29808 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Granting...

    Science.gov (United States)

    2011-05-23

    ... COMMISSION Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Granting... Distributions) May 18, 2011. I. Introduction On April 26, 2011, the Financial Industry Regulatory Authority, Inc... 29, 2011. II. Description of the Proposed Rule Change On November 29, 2010, FINRA issued...

  17. A Comparison Study of Augmented Reality versus Interactive Simulation Technology to Support Student Learning of a Socio-Scientific Issue

    Science.gov (United States)

    Chang, Hsin-Yi; Hsu, Ying-Shao; Wu, Hsin-Kai

    2016-01-01

    We investigated the impact of an augmented reality (AR) versus interactive simulation (IS) activity incorporated in a computer learning environment to facilitate students' learning of a socio-scientific issue (SSI) on nuclear power plants and radiation pollution. We employed a quasi-experimental research design. Two classes (a total of 45…

  18. FINESSE: study of the issues, experiments and facilities for fusion nuclear technology research and development. Interim report. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.

    1984-10-01

    The following chapters are included in this study: (1) fusion nuclear issues, (2) survey of experimental needs, (3) requirements of the experiments, (4) non-fusion facilities, (5) fusion facilities for nuclear experiments, and (6) fusion research and development scenarios. (MOW)

  19. Regulatory Anatomy

    DEFF Research Database (Denmark)

    Hoeyer, Klaus

    2015-01-01

    This article proposes the term “safety logics” to understand attempts within the European Union (EU) to harmonize member state legislation to ensure a safe and stable supply of human biological material for transplants and transfusions. With safety logics, I refer to assemblages of discourses, le...... they arise. In short, I expose the regulatory anatomy of the policy landscape....

  20. Application of integrated remote sensing and GIS technologies to geoenvironmental issues in far west Texas and southern New Mexico

    Science.gov (United States)

    Perez, Adriana Evangelina

    The primary goal of this dissertation was to utilize a geographic information system (GIS) to better understand geological, geophysical, forestry and environmental issues in the west Texas-New Mexico region. Studies such as these are especially important in the border region where economic limitations are usually a factor in studying and solving some of these problems. The availability of satellite imagery through the Pan-American Center for Earth and Environmental Studies (PACES), data from the Geospatial Center and the collaboration with the United States Department of Agriculture (USDA) and National Forest entities (Guadalupe and Lincoln Ranger Districts) enhance the value of our investigation. Research was conducted in two distinct areas: Cloudcroft-Ruidoso, New Mexico, and the Salt Flat basin of southwest Texas (Figure 1). The dissertation will be presented as a set of independent chapters. Chapter 1. A GIS and remote sensing investigation of the effects of interactions of terrain, soil, and other physiographic factors on the Pine Community of Lincoln National Park in the Sacramento Mountains of Southwest New Mexico. This study utilized GIS and remote sensing to better understand the dynamics of White Pine Blister Rust (WPBR) infestation in the white pine community of the Sacramento Mountains of southwest New Mexico. Both field spectral sampling of the needles and imagery analysis were incorporated to better understand the infestation, progression and vulnerability of the forest to this and other diseases. A major contribution of this study was to construct a GIS database, which was utilized to analyze USDA, elevation, satellite imagery, geological, and hydrological data to produce a hazard-rating map. The GIS environment also allowed for a 3-D perspective on the data, which was very useful in spatial visualization. Chapter 2. An integrated study of the basin structure of the Salt Flat basin. In this study we utilized, gravity and magnetic data, satellite

  1. Low-noise design issues for analog front-end electronics in 130 nm and 90 nm CMOS technologies

    CERN Document Server

    Manghisoni, M; Re, V; Speziali, V; Traversi, G

    2007-01-01

    Deep sub-micron CMOS technologies provide wellestablished solutions to the implementation of low-noise front-end electronics in various detector applications. The IC designers’ effort is presently shifting to 130 nm CMOS technologies, or even to the next technology node, to implement readout integrated circuits for silicon strip and pixel detectors, in view of future HEP applications. In this work the results of noise measurements carried out on CMOS devices in 130 nm and 90 nm commercial processes are presented. The behavior of the 1/f and white noise terms is studied as a function of the device polarity and of the gate length and width. The study is focused on low current density applications where devices are biased in weak or moderate inversion. Data obtained from the measurements provide a powerful tool to establish design criteria in nanoscale CMOS processes for detector front-ends in LHC upgrades.

  2. 我国池塘增氧技术现状与发展趋势%The development status, issues and trends of pond aeration technology in China

    Institute of Scientific and Technical Information of China (English)

    顾海涛; 王逸清

    2014-01-01

    The technology of pond aeration have developed in China for over 40 years since the emergence of first impeller aerator in 1972, which is one of the main driving factors that the total aquaculture output of China ranked first in the world for 24 consecutive years. This article analyzed the current status of the pond aeration technology in China, classified and elaborated impeller aerator, wave aerator and aerator with solar technology as mature technology, innovative technology and budding technology respectively. Simultaneously, the issues such as lack of evaluation method for the innovative technology, weak research and development capabilities and small efforts for new technology extension were put forward, which are all the bottleneck for the further development of pond aeration technology. Finally, the development trends of pond aeration technology were discussed based on new changes and features of aquaculture industry, such as the low energy consumption, recirculating aquaculture system, and the application of digital and intelligent technology in pond aeration.%以1972年第一台叶轮式增氧机的诞生为标志,池塘增氧技术在我国发展了40多年,它是我国养殖总产量连续24年位居世界第一的主要因素之一。通过对目前国内池塘增氧技术的现状进行分析,将叶轮式增氧机、涌浪式增氧机和太阳能技术在池塘增氧中的应用分别划分为成熟技术、创新技术和萌芽技术,并进行了阐述;指出目前存在的缺乏对创新技术的评价方法、研发能力不足、缺少对新技术的推广力度等问题是制约池塘增氧技术进一步发展的瓶颈,同时结合水产养殖发展的新变化、新特点,对池塘增氧技术发展的趋势进行了探讨。

  3. Development of core technology for KNGR system design; detailed analysis and related issue evaluation for MMI testing data

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dhong Ha [Suwon University, Whasung (Korea)

    2002-03-01

    This study evaluated man-machine interface (MMI) features of the advanced control room of Korea Next Generation Reactor. Major issues to be evaluated included: (1) supportability of large display panel (LDP) during passive monitoring (2) supportability of work station display (WSD) for interpretation and planning (3) supportability of combination of alarm, WSD, LDP and computerized procedure system (CPS) for interpretation and planning during single and multiple fault event, (4) supportability of softcontrol (SC) during simple operator-paced control task, (5) supportability of softcontrol (SC) during conditional operator-paced control task, and (6) supportability of alarm system for emergent operation procedure. Four operator teams of RO, TO, and SRO participated the test scenarios consisting of AOP and EOP. Performance data measuring situation awareness, workload, operation errors, and team work and operators' opinions for MMI features of advanced control room were collected during the experiment. Operators showed positive responses for issues (1) supportability of LDP during passive monitoring (2) supportability of WSD for interpretation and planning (3) supportability of combination of alarm, WSD, LDP and CPS for interpretation and planning during single and multiple fault event, (4) supportability of alarm system for normal operation procedure, while they suggested some needs to improve for issues: (1) supportability of softcontrol (SC) during simple and conditional operator-paced control task, (2) supportability of alarm system for emergent situation. 7 refs., 36 figs., 83 tabs. (Author)

  4. Effective Use of Assistive Technologies for Inclusive Education in Developing Countries: Issues and Challenges from Two Case Studies

    Science.gov (United States)

    Grönlund, Åke; Lim, Nena; Larsson, Hannu

    2010-01-01

    Developing countries face many obstacles in the process of implementing inclusive education (IE). Effective use of assistive technologies (AT) can help governments in developing countries achieve inclusive education by helping children with disabilities in schools. Despite the importance and positive impact of AT, prior research on the use of AT…

  5. Globalization, Information and Communication Technologies (ICTs) and Open/Distance Learning in Nigeria: Trends, Issues and Solution

    Science.gov (United States)

    Olusola, Akande Joshua; Alaba, Sofowora Olaniyi

    2011-01-01

    The main thrust of this paper is to discuss the development of open and distance education in Nigeria and the major manifestations of the use of information and communication technologies (ICTs) in education in open and distance learning. This study further discusses the importance and use of ICTs in open and distance learning in making education…

  6. A Review of the Environmental Impacts for Marine and Hydrokinetic Projects to Inform Regulatory Permitting: Summary Findings from the 2015 Workshop on Marine and Hydrokinetic Technologies, Washington, D.C.

    Energy Technology Data Exchange (ETDEWEB)

    Baring-Gould, E. Ian [National Renewable Energy Lab. (NREL), Golden, CO (United States); Christol, Corrie [National Renewable Energy Lab. (NREL), Golden, CO (United States); LiVecchi, Al [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kramer, Sharon [H.T. Harvey and Associates, Los Gatos, CA (United States); West, Anna [Kearns & West, Inc., San Francisco, CA (United States)

    2016-07-01

    In 2014 and 2015, the U.S. Department of Energy initiated efforts to develop and implement technology- and application-focused marine and hydrokinetic (MHK) workshops to share the global experience and knowledge base on evolving MHK technologies, observed and not-observed impacts, monitoring and measurement methods, and regulatory needs. The resulting MHK Regulator Workshops engaged resource managers and other decision makers at key regulatory organizations, scientists, researchers, facilitators, and technical experts and provided an opportunity to examine the risks of single-device and small-scale deployments, explore what can be learned and observed from single devices and small-scale arrays, and consider requirements for projects at varying scales of deployment. Experts and stakeholders identified key remaining information gaps. Initial discussions focused on differentiating between monitoring required for single or small-scale deployments and MHK impact research that, although important, goes beyond what is feasible or should be needed to meet specific project regulatory requirements but is appropriate for broader research and development. Four areas of identified potential environmental impacts provided the focus for the workshop: acoustic output impacts, electromagnetic field (EMF) emissions, physical interactions, and environmental effects of MHK energy development on the physical environment. Discussions also focused on the regulatory process and experience, adaptive management, industry drivers, and lessons that can be learned from the wind energy industry. The discussion was set in the context of the types of MHK technologies that are currently proposed or planned in the United States. All presentations and the following discussions are summarized in this document.

  7. Research and Solutions for Issues of Marine Standards Technology Examination%海洋标准技术审查问题研究与对策建议

    Institute of Scientific and Technical Information of China (English)

    汤海荣; 粟义; 叶盛林; 张文娜

    2013-01-01

    Citing the marine environment protection standards, this paper presents the main issues of the marine standards technology examination, analyses the cause, and puts forward the corresponding solutions to search for method to enhance efifciency of standard technology examination.%本文以海洋环境保护标准为例,阐述了海洋标准技术审查工作中存在的主要问题,分析了问题产生的原因,并在此基础上提出了相应的对策建议,以寻求提高标准技术审查工作效率的方法和途径。

  8. The Algorithm Analysis of E-Commerce Security Issues for Online Payment Transaction System in Banking Technology

    CERN Document Server

    Barskar, Raju; Bharti, Jyoti; Ahmed, Gulfishan Firdose

    2010-01-01

    E-Commerce offers the banking industry great opportunity, but also creates a set of new risks and vulnerability such as security threats. Information security, therefore, is an essential management and technical requirement for any efficient and effective Payment transaction activities over the internet. Still, its definition is a complex endeavor due to the constant technological and business change and requires a coordinated match of algorithm and technical solutions. Ecommerce is not appropriate to all business transactions and, within e-commerce there is no one technology that can or should be appropriate to all requirements. E-commerce is not a new phenomenon; electronic markets, electronic data interchange and customer e-commerce. The use of electronic data interchanges as a universal and non-proprietary way of doing business. Through the electronic transaction the security is the most important phenomena to enhance the banking transaction security via payment transaction.

  9. The Algorithm Analysis of E-Commerce Security Issues for Online Payment Transaction System in Banking Technology

    OpenAIRE

    Raju Barskar; Anjana Jayant Deen; yoti Bharti; Gulfishan Firdose Ahmed

    2010-01-01

    E-Commerce offers the banking industry great opportunity, but also creates a set of new risks and vulnerability such as security threats. Information security, therefore, is an essential management and technical requirement for any efficient and effective Payment transaction activities over the internet. Still, its definition is a complex endeavor due to the constant technological and business change and requires a coordinated match of algorithm and technical solutions. Ecommerce is not appro...

  10. FINESSE: study of the issues, experiments and facilities for fusion nuclear technology research and development. Interim report. Volume III

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.

    1984-10-01

    This chapter deals with the analysis and engineering scaling of solid breeded blankets. The limits under which full component behavior can be achieved under changed test conditions are explored. The characterization of these test requirements for integrated testing contributes to the overall test matrix and test plan for the understanding and development of fusion nuclear technology. The second chapter covers the analysis and engineering scaling of liquid metal blankets. The testing goals for a complete blanket program are described. (MOW)

  11. FINESSE: study of the issues, experiments and facilities for fusion nuclear technology research and development. Interim report. Volume III

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.

    1984-10-01

    This chapter deals with the analysis and engineering scaling of solid breeded blankets. The limits under which full component behavior can be achieved under changed test conditions are explored. The characterization of these test requirements for integrated testing contributes to the overall test matrix and test plan for the understanding and development of fusion nuclear technology. The second chapter covers the analysis and engineering scaling of liquid metal blankets. The testing goals for a complete blanket program are described. (MOW)

  12. Ethical and security issues associated to the usage of technologies regarding with information and knowledge on the health field.

    Directory of Open Access Journals (Sweden)

    Alain Francisco Morejón Giraldoni

    2008-04-01

    Full Text Available Cuban people are going to go to the construction of the informational society based on the principles of equity and accessibility. The health field or area is not distant to this development, so it is of special interest the ethical treatment of the usage of the new technologies of the informational area, so that the fulfillment of the confidentialness, integrity, and availability requisites through computer science safeness is allowed.

  13. [Problematic issues and prospects of development of information and telecommunication technologies in the medical service of the Armed Forces].

    Science.gov (United States)

    Kalachev, O V; Pershin, I V; Borisov, D N; Korneenkov, A A

    2014-12-01

    Medical information systems composed of many specialized modules help in synchronous solving of diagnostic, therapeutic, administrative, financial, statistical, and other tasks. According to the authors, the creation of a single information space of the medical service, integrating it into a single information space of the Defense Ministry of the Russian Fedaration, development and widespread use of telemedicine technology will significantly accelerate the integration in the daily activities of military hospitals of the latest achievements in medical science and practices consistent with the objectives of improving the military health care and improvement of the quality and accessibility of health care.

  14. Leadership and New Technologies. New Security Issues for Management of Internet Connectivity and Remote Control in Automotive Industry

    Directory of Open Access Journals (Sweden)

    Cosmin Cătălin Olteanu

    2015-05-01

    Full Text Available The main purpose of the paper is to illustrate the importance of implementing new security policies for infotainment systems in automotive industry. A car is full of technology and is easier today to control car systems through an internet connection linked to car system infotainment. This is how it is possible to gain control of critical car systems. More than 84% of users doesn’t even know the risk of remote control of the car in the presence of Internet connection.

  15. Proceedings of the Third Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies.

    Science.gov (United States)

    Rossi, P Justin; Gunduz, Aysegul; Judy, Jack; Wilson, Linda; Machado, Andre; Giordano, James J; Elias, W Jeff; Rossi, Marvin A; Butson, Christopher L; Fox, Michael D; McIntyre, Cameron C; Pouratian, Nader; Swann, Nicole C; de Hemptinne, Coralie; Gross, Robert E; Chizeck, Howard J; Tagliati, Michele; Lozano, Andres M; Goodman, Wayne; Langevin, Jean-Philippe; Alterman, Ron L; Akbar, Umer; Gerhardt, Greg A; Grill, Warren M; Hallett, Mark; Herrington, Todd; Herron, Jeffrey; van Horne, Craig; Kopell, Brian H; Lang, Anthony E; Lungu, Codrin; Martinez-Ramirez, Daniel; Mogilner, Alon Y; Molina, Rene; Opri, Enrico; Otto, Kevin J; Oweiss, Karim G; Pathak, Yagna; Shukla, Aparna; Shute, Jonathan; Sheth, Sameer A; Shih, Ludy C; Steinke, G Karl; Tröster, Alexander I; Vanegas, Nora; Zaghloul, Kareem A; Cendejas-Zaragoza, Leopoldo; Verhagen, Leonard; Foote, Kelly D; Okun, Michael S

    2016-01-01

    The proceedings of the 3rd Annual Deep Brain Stimulation Think Tank summarize the most contemporary clinical, electrophysiological, imaging, and computational work on DBS for the treatment of neurological and neuropsychiatric disease. Significant innovations of the past year are emphasized. The Think Tank's contributors represent a unique multidisciplinary ensemble of expert neurologists, neurosurgeons, neuropsychologists, psychiatrists, scientists, engineers, and members of industry. Presentations and discussions covered a broad range of topics, including policy and advocacy considerations for the future of DBS, connectomic approaches to DBS targeting, developments in electrophysiology and related strides toward responsive DBS systems, and recent developments in sensor and device technologies.

  16. 简政放权、放管结合下的监管问题研究--基于回应性监管理论的分析%Regulatory Issues of Streamline Administration and Decentralization and Delegating Power While Enforcing Government Regulations---Analysis Based on Theory of Responsive Regulation

    Institute of Scientific and Technical Information of China (English)

    陈自立

    2016-01-01

    With the new normal ofstreamline administration anddecentralization , the regulatory issues of del-egating power while enforcing government regulations become more important .The theory of responsive regu-lation of western countries provides reference methods for China ’ s regulatory problems .Facing the problems of the lack of supervision of the regulatory , single subject of supervision , regulatory methods backward and regulatory “revolving door”, China shouldabsorbcreatively core elements of the theory of responsive regula -tion ,construct a diversified regulatory system and participate in the diversification of the main responsibilities of the regulatory system , combined with the actual situation in China to ensure that the government would deepen the implementation of the administrative reform objectives .%随着简政放权步入新常态,放管结合中的监管问题变得越来越突出,西方国家的回应性监管理论为我国监管问题提供借鉴方法。面对我国监管领域出现的监管缺失、监管主体单一、监管方法落后和监管“旋转门”问题,我国应创造性地吸收回应性监管理论的核心要点,结合中国实际情况,构建监管手段多样化、参与主体多元化的权责分明的监管治理体系,保证政府深化行政改革目标的实现。

  17. Needs Analysis: Strategic Issue on the Teaching of English for Specific Purposes for the Study of Sciences and Technology

    Directory of Open Access Journals (Sweden)

    Lubna Algadrie

    2002-01-01

    Full Text Available Abstract: With the development of science and technology scholars and professionals now need to acquire a higher form of literacy to be able to participate in groups of similar fields or groups of works. The need for English as one of the International language, an established language, has increased because English has access to world knowledge particularly in the field of science and technology, computer utilization, international trade and commerce. However, the need can vary in terms of the study fields, selection of skills, selection of language functions, and the language learners. Effective strategies can only be applied through a thorough analysis of the learners' needs, which will refer to the whole range of language resources for material selection. Since it is clear that ESP course is directly concerned with the purposes of which the learners need English, ESP course should be learner-centered. In this paper the writer would like to give the results of needs analysis (wants and strategies: Shaw, 1982, Allwright and Allwright, 1997 done among the learners (students and lecturers of engineering studies from various departments of Institut Teknologi Sepuluh Nopember Surabaya (ITS who are learning English at ITS Language Center to fulfill the market demand for job employment of their career and further studies.

  18. Needs Analysis: Strategic Issue on the Teaching of English for Specific Purposes for the Study of Sciences and Technology

    Directory of Open Access Journals (Sweden)

    Lubna Algadrie

    2003-01-01

    Full Text Available With the development of science and technology scholars and professionals now need to acquire a higher form of literacy to be able to participate in groups of similar fields or groups of works. The need for English as one of the International language, an established language, has increased because English has access to world knowledge particularly in the field of science and technology, computer utilization, international trade and commerce. However, the need can vary in terms of the study fields, selection of skills, selection of language functions, and the language learners. Effective strategies can only be applied through a thorough analysis of the learners' needs, which will refer to the whole range of language resources for material selection. Since it is clear that ESP course is directly concerned with the purposes of which the learners need English, ESP course should be learner-centered. In this paper the writer would like to give the results of needs analysis (wants and strategies: Shaw, 1982, Allwright and Allwright, 1997 done among the learners (students and lecturers of engineering studies from various departments of Institut Teknologi Sepuluh Nopember Surabaya (ITS who are learning English at ITS Language Center to fulfill the market demand for job employment of their career and further studies.

  19. Oak Ridge National Laboratory Technology Logic Diagram. Volume 1, Technology Evaluation: Part A, Decontamination and Decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Strategic Roadmap for the Oak Ridge Reservation is a generalized planning document that identifies broad categories of issues that keep ORNL outside full compliance with the law and other legally binding agreements. Possible generic paths to compliance, issues, and the schedule for resolution of the issues one identified. The role of the Oak Ridge National Laboratory Technology Logic Diagram (TLD) is then to identify specific site issues (problems), identify specific technologies that can be brought to bear on the issues, and assess the current status and readiness of these remediation technologies within the constraints of the schedule commitment. Regulatory requirements and commitments contained in the Strategic Roadmap for the Oak Ridge Reservation are also included in the TLD as constraints to the application of immature technological solutions. Some otherwise attractive technological solutions may not be employed because they may not be deployable on the schedule enumerated in the regulatory agreements. The roadmap for ORNL includes a list of 46 comprehensive logic diagrams for WM of low-level, radioactive-mixed, hazardous, sanitary and industrial. and TRU waste. The roadmapping process gives comparisons of the installation as it exists to the way the installation should exist under full compliance. The identification of the issues is the goal of roadmapping. This allows accurate and timely formulation of activities.

  20. The Challenges and Issues Regarding E-Health and Health Information Technology Trends in the Healthcare Sector

    Science.gov (United States)

    Esmaeilzadeh, Pouyan; Sambasivan, Murali; Kumar, Naresh

    Like other industries, the utilization of the internet and Information Technology (IT) has increased in the health sector. Different applications attributed to the internet and IT in healthcare practice. It includes a range of services that intersect the edge of medicine, computer and information science. The presence of the internet helps healthcare practice with the use of electronic processes and communication. Also, health IT (HIT) deals with the devices, clinical guidelines and methods required to improve the management of information in healthcare. Although the internet and HIT has been considered as an influential means to enhance health care delivery, it is completely naive to imagine all new tools and mechanisms supported by the internet and HIT systems are simply adopted and used by all organizational members. As healthcare professionals play an important role in the healthcare sector, there is no doubt that mechanism of newly introduced HIT and new application of the internet in medical practice should be coupled with healthcare professionals' acceptance. Therefore, with great resistance by healthcare professionals new mechanism and tools supported by IT and the internet cannot be used properly and subsequently may not improve the quality of medical care services. However, factors affecting the healthcare professionals' adoption behavior concerning new e-health and HIT mechanism are still not conclusively identified. This research (as a theoretical study) tries to propose the source of resistance in order to handle the challenges over new e-technology in the health industry. This study uses the involved concepts and develops a conceptual framework to improve overall acceptance of e-health and HIT by healthcare professionals.

  1. Innovative farmers and regulatory gatekeepers: Genetically modified crops regulation and adoption in developing countries.

    Science.gov (United States)

    Sinebo, Woldeyesus; Maredia, Karim

    2016-01-02

    The regulation of genetically modified (GM) crops is a topical issue in agriculture and environment over the past 2 decades. The objective of this paper is to recount regulatory and adoption practices in some developing countries that have successfully adopted GM crops so that aspiring countries may draw useful lessons and best practices for their biosafatey regulatory regimes. The first 11 mega-GM crops growing countries each with an area of more than one million hectares in 2014 were examined. Only five out of the 11 countries had smooth and orderly adoption of these crops as per the regulatory requirement of each country. In the remaining 6 countries (all developing countries), GM crops were either introduced across borders without official authorization, released prior to regulatory approval or unapproved seeds were sold along with the approved ones in violation to the existing regulations. Rapid expansion of transgenic crops over the past 2 decades in the developing world was a result of an intense desire by farmers to adopt these crops irrespective of regulatory roadblocks. Lack of workable biosafety regulatory system and political will to support GM crops encouraged unauthorized access to GM crop varieties. In certain cases, unregulated access in turn appeared to result in the adoption of substandard or spurious technology which undermined performance and productivity. An optimal interaction among the national agricultural innovation systems, biosafety regulatory bodies, biotech companies and high level policy makers is vital in making a workable regulated progress in the adoption of GM crops. Factoring forgone opportunities to farmers to benefit from GM crops arising from overregulation into biosafety risk analysis and decision making is suggested. Building functional biosafety regulatory systems that balances the needs of farmers to access and utilize the GM technology with the regulatory imperatives to ensure adequate safety to the environment and human

  2. Regulatory and Non-regulatory Responses to Hydraulic Fracturing in Local Communities

    Science.gov (United States)

    Phartiyal, P.

    2015-12-01

    The practice of extracting oil and gas from tight rock formations using advances in technology, such as hydraulic fracturing and directional drilling, has expanded exponentially in states and localities across the country. As the scientific data collection and analysis catches up on the many potential impacts of this unconventional oil and gas development, communities are turning to their local officials to make decisions on whether and how fracking should proceed. While most regulatory authority on the issue rests with the state agencies, local officials have experimented with a wide range of regulatory, non-regulatory, and fiscal tools to manage the impacts of fracking. These impacts can occur on the local air, water, seismicity, soil, roads, schools, and affect residents, on-site workers, emergency and social services. Local officials' approaches are often influenced by their prior experience with minerals extraction in their localities. The speaker will present examples of the kinds of information sources, tools and approaches communities across the country are using, from noise barriers to setback requirements to information sharing in order to be able to balance the promise and perils of oil and gas development in their jurisdictions.

  3. ATMPs for Cancer Immunotherapy: A Regulatory Overview.

    Science.gov (United States)

    Galli, Maria Cristina

    2016-01-01

    This chapter discusses European regulatory requirements for development of advanced therapy medicinal products (ATMP) for cancer immunotherapy approaches, describing the framework for clinical trials and for marketing authorization.Regulatory critical issues and challenges for developing ATMP are also discussed, with focus on potency determination, long-term follow-up, comparability, and insertional mutagenesis issues. Some of the most critical features of GMP application to ATMP are also described.

  4. Next Generation Public Safety and Emergency Technologies

    DEFF Research Database (Denmark)

    Bonde, Camilla; Tadayoni, Reza; Skouby, Knud Erik

    2014-01-01

    The paper researches the existing European standards for Public Safety and Emergency (PSE) services (also called Public Protection Disaster Relief “PPDR”), and identifies based on user studies in Denmark conflicts between the current deployments of the standards and the user requirements. The aim...... is further to identify the potentials of new technologies for PSE. The paper deals with policy and technology frameworks, regulatory issues and in particular the spectrum issues in the current PPDR deployments in the EU countries. The paper draws on the results and concepts developed in two EU...

  5. Ethical Issues and Decision Making in Collaborative Financial Therapy

    Directory of Open Access Journals (Sweden)

    D. Bruce Ross

    2016-09-01

    Full Text Available The purpose of this article is to introduce potential ethical challenges that may arise when a financial and mental health professional collaborate to provide financial therapy and recommendations on how to effectively address these concerns. The development of ethical and professional practices requires extensive dialogue from practitioners in the emerging field of financial therapy; however, it is important to first develop an awareness and sensitivity to the ethical and professional issues across disciplines. This article examines the differences and similarities between the codes of ethics of different financial and mental health disciplines, and addresses six core ethical and professional issues: dual relationships, confidentiality, collaborating with other professionals, fee management, use of technology, and attending to federal and state regulatory laws. In working through the complexity of different disciplines’ regulatory environments, a discussion of how to address these ethical questions in order to progress the financial therapy field is presented.

  6. Food irradiation--US regulatory considerations

    Energy Technology Data Exchange (ETDEWEB)

    Morehouse, Kim M. E-mail: kim.morehouse@cfsan.fda.gov

    2002-03-01

    The use of ionizing radiation in food processing has received increased interest as a means of reducing the level of foodborne pathogens. This overview discusses the regulatory issues connected with the use of this technology in the United States. Several recent changes in the FDA's review process are discussed. These include the current policy that utilizes an expedited review process for petitions seeking approval of additives and technologies intended to reduce pathogen levels in food, and the recent USDA rule that eliminates the need for a separate rulemaking process by USDA for irradiation of meat and poultry. Recently promulgated rules and pending petitions before the FDA associated with the use of ionizing radiation for the treatment of foods are also discussed along with the current FDA labeling requirements for irradiated foods and the 1999 advanced notice of proposed rule on labeling. Another issue that is presented is the current status of the approval of packaging materials intended for food contact during irradiation treatment of foods.

  7. Memoirs of law, sciences and technologies - Law and climate thematic issue; Cahiers droit, sciences et technologies - Dossier thematique droit et climat

    Energy Technology Data Exchange (ETDEWEB)

    Torre-Schaub, M. [CNRS, IDHE ENS-Cachan (France); Jouzel, J. [IPSL-LSCE, CEA-CNRS, UVSQ, CE Saclay 91191 Gif-sur-Yvette Cedex (France); Boisson de Chazournes, L. [Faculte de droit, Geneve Univ. (Switzerland); Sadeleer, N. de; Denis, B. [Saint-Louis Univ., Brussels (Belgium); Godard, O. [CNRS-Ecole Polytechnique, Dep. Humanites et Sciences Sociales (France); Le Prestre, P. [Laval univ. (Canada); Maljean-Dubois, S. [CNRS, CERIC, Paul Cezanne Univ., Aix-en-Provence (France); Wemaere, M. [IDDRI, Dep. Climat et Energie (France); Rousseaux, S. [CNRS, Droit et Changement Social, Association Climaterre (France); Louchard, O. [Reseau Action Climat (France)

    2009-07-01

    extraordinary process of standards elaboration devoted to mitigate the difficulties generated by the global warming in various domains, like the building industry, the transports or the energy sectors. This book is organized in two parts. Part one deals with climate as a scientific question between science and governance: the inter-disciplinary nature in the center of the problem, the law and the universality of the fight against climatic change, the precaution principle and the fight against climatic change, the economy of climatic change, the civil society and the international climate policy. The second part treats of the globalization of the climate issue: regional climate geopolitics and international cooperation, the post-Kyoto perspectives of the international legal framework of fight against climatic change, the legal architecture of a future international agreement of fight against climatic change, the climate governance between old notions and new stakes, the legal stakes of the implementation of emissions trading markets, the emissions trading system in the European Communities, and the 'Grenelle de l'Environnement' experience feedback. (J.S.)

  8. Used battery collection camping in central Mexico: statics and metal content report, advances in recycling technology and legislative/regulatory situation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Guevara-Garcia, J. A.; Montiel-Corona, V.; Juarez Galindo, A.; Mendoza Sarmiento, G.; Munoz Lopez, F.; Papalotzi Juarez, S.; Cruz Diaz, R. de la

    2009-07-01

    Nowadays, environmental pollution produced by the disposal of used cells and batteries is a major concern in Mexico. The regulatory law proposal (NMX-AA-104-SCFI-2006) establish a content limit 20, 7.5 and 5 fold higher in Hg, Cd and Pb, respectively, than the European directive 2006/66/CE. Furthermore, transnational companies refused to have participation on the collection/recycling process, putting forward that pollution comes only from illegal market batteries. (Author)

  9. Materials Issues Related to Catalysts for Treatment of Diesel Exhaust

    Energy Technology Data Exchange (ETDEWEB)

    Narula, Chaitanya Kumar [ORNL; Daw, C Stuart [ORNL; Hoard, John W. [Ford Motor Company; Hammer, T. [Siemens AG, Germany

    2005-01-01

    The driver for lean NO{sub x} treatment is the need to meet regulatory standards for diesel engines and gasoline direct injection spark-ignited engines that offer better fuel economy. Efforts over the last decade have been focused toward finding an active lean NO{sub x} catalyst that can reduce NO{sub x} under oxidizing conditions or strategies such as selective catalytic reduction (SCR), plasma-catalysis, plasma catalyst SCR, and lean NO{sub x} traps with varying degrees of success. At present, it appears that SCR with urea and lean NO{sub x} traps are the leading contender technologies for commercial deployment. Key issues that remain to be resolved for these two technologies include byproduct formation, dosing control, and durability. In this review, we summarize material-related issues that are unique to each of these technologies, and point out the improvements necessary to facilitate their deployment.

  10. Regulatory Reform: Low Risk, High Promise.

    Science.gov (United States)

    Tanenbaum, Morris

    The press of telecommunication technologies and their progeny have undermined the natural monopoly basis for long distance telecommunications and customer premise products, forced open regulatory doors, toppled barriers to market entry, and led to the reshaping of regulatory philosophy as regulators have seen new, wider horizons for the industry.…

  11. 76 FR 59066 - Notice of Regulatory Review Plan

    Science.gov (United States)

    2011-09-23

    ...; ] FEDERAL HOUSING FINANCE AGENCY 12 CFR Chapter XII Notice of Regulatory Review Plan AGENCY: Federal Housing...) is issuing a notice of and requesting comments on the FHFA interim regulatory review plan for review.... Comments FHFA invites comments on all aspects of the interim regulatory review plan, including legal...

  12. Toxicogenomics in regulatory ecotoxicology

    Science.gov (United States)

    Ankley, Gerald T.; Daston, George P.; Degitz, Sigmund J.; Denslow, Nancy D.; Hoke, Robert A.; Kennedy, Sean W.; Miracle, Ann L.; Perkins, Edward J.; Snape, Jason; Tillitt, Donald E.; Tyler, Charles R.; Versteeg, Donald

    2006-01-01

    Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has become a rapidly growing topical area in multiple biological disciplines. Since 1999, when the term “toxicogenomics” was coined to describe the application of genomics to toxicology (1), a rapid increase in publications on the topic has occurred (Figure 1). The potential utility of toxicogenomics in toxicological research and regulatory activities has been the subject of scientific discussions and, as with any new technology, has evoked a wide range of opinion (2–6). VIEWPOINT © 2006 american chemical Society july 1, 2006 / EnvironmEntal SciEncE & tEchnology n 4055 The purpose of this feature article is to consider the roles of toxicogenomics in the field of regulatory ecotoxicology, explore current limitations in the science and practice of genomics, and propose possible avenues to approach and resolve some of the major challenges. A significant amount of input to our analysis came from a workshop sponsored by the Society of Environmental Toxicology and Chemistry (SETAC) in Pellston, Mich., in September 2005. A complete list of names and affiliations of the experts participating in that workshop is provided online in Table 1 of the Supporting Information for this paper.

  13. Electricity distribution networks: Changing regulatory approaches

    Science.gov (United States)

    Cambini, Carlo

    2016-09-01

    Increasing the penetration of distributed generation and smart grid technologies requires substantial investments. A study proposes an innovative approach that combines four regulatory tools to provide economic incentives for distribution system operators to facilitate these innovative practices.

  14. Bioethical issues in the development of biopharmaceuticals

    Directory of Open Access Journals (Sweden)

    Todorović Zoran

    2012-01-01

    Full Text Available Development of biopharmaceuticals is a challenging issue in bioethics. Unlike conventional, small molecular weight drugs, biopharmaceuticals are proteins derived from DNA technology and hybrid techniques with complex three dimensional structures. Immunogenicity of biopharmaceuticals should always be tested in clinical settings due to low predictive value of preclinical animal models. However, non-human primates (NHP and transgenic mice could be used to address certain aspects of immunogenicity. Substantial efforts have been made to reduce NHP use in biopharmaceutical drug development, e.g. study design improvements and changes in regulatory policy. In addition, several expert groups are active in this field (e.g. NC3Rs, BioSafe, and Biopharmaceutical Technical Group. Despite that, there is an increasing trend of use of NHP in preclinical safety testing of biopharmaceuticals, especially regarding monoclonal antibodies. Other potential bioethical issues related biopharmaceutical drug development are their cost/effectiveness ratio, clinical safety assessment, production of biosimilars, and comparison of their efficacy with placebo in countries without intention to market. Identification of the human genome has opened many new bioethical issues. Development of biopharmaceuticals is an important bioethical issue for several reasons. It connects all aspects of contemporary bioethics: bio­medicine (e.g. clinical trials in vulnerable subjects, animal welfare and the most recent ad­vances in biotechnology. In particular, biopharmaceutical drug development is a challenging issue regarding treatment of rare diseases.

  15. 关于网格及其它分布计算技术的若干问题的讨论%Discussion of Serval Issues for Gird and other Distributed Computing Technologies

    Institute of Scientific and Technical Information of China (English)

    高全泉

    2003-01-01

    Grid computing is a new field which distinguished from conventional distributed computing by its focus on large-scale virtual organizations resources sharing. Thispaper presents discussion of serval issues for Grid technologies and other contemporary distributed computing technologies. First, we introduce enterprise computing technologies in brief,including CORBA,DCOM, Java,Enterprise JavaBeans and J2EE ,and discuss how Grid technologies related to them. Next,we introduce an Internet-based parallel computing technology named Javelin. Other distrbuted computing technologies and how them related to Grid technologies are discussed. Finaly,we discuss the need of intergrid protocols to enable interoperability among different Grid systems,and serval other perspectives on Grids are also disscused.

  16. Roadmapping as a Tool for Renewing Regulatory Practices

    DEFF Research Database (Denmark)

    Borch, Kristian; Norus, Jesper

    2004-01-01

    The aim of this paper is to explore technological roadmaps to identify key issuesconcerning the development and utilization of stem cells. From a review of the politicaldecision making processes in three countries, Denmark, the Netherlands, and Germanywe suggest that technological roadmapping...... in this emerging and discontinuedtechnology can provide critical policy information. This type of policy intelligence canbe used to rethink the regulatory practices away from today's framework basedregulation of the emerging technologies towards a regulatory policy based on how todevelop regulatory practices based...

  17. IPTV Market Development and Regulatory Aspects

    DEFF Research Database (Denmark)

    Tadayoni, Reza; Sigurdsson, Halldór Matthias

    2006-01-01

    The aim of this paper is to analyse the development of IPTV technology / market and to discuss major regulatory parameters. A general overview of architectures and the technologies deployed for establishing IPTV services is given and the main stake holder identified, along with, the current service...... architecture, the available content in IPTV platforms, and the current business models. Furthermore the regulatory framework of the TV broadcast and IPTV in Europe is analysed....

  18. 农村金融服务可获得性:监管问题与制度创新%Accessibility of Financial Service: Regulatory Issues and Institutional Innovation

    Institute of Scientific and Technical Information of China (English)

    孟飞

    2009-01-01

    Agricultural development and new socialism rural construction can't go well without financial support.So access to finance plays important role in the eradication of poverty.Finandal regulatory institutional envilonments enhance accessibility to finance.Financial institutional innovation includes regulatory objecta,approach,principles,and others.As to regulatory objects,regulator must adopt access to finance to enhance accountability and regulatory qualiry.Moreover,we must use incentive - regulation principle, tiered regulation and risk - based regulation approaches to boost financial supply ability.And financial regulator adopts new strategies on market entrance and prudential regulation, with the economic policies and financial technical safeguards.%发展现代农业,建设社会主义新农村,离不开金融服务的有效支持.金融服务可获得性的实质在于保障农民的金融发展权.而金融监管制度环境在保障金融服务可获得性方面发挥着基础性的作用.我国金融监管制度在监管目标、监管原则、监管方法和监管内容方面给予变革和创新.在监管目标中,应当纳入金融服务的可获得性.为提高金融机构提高金融供给能力,我国应当实施激励监管、分类监管和风险监管的方法.金融监管还需要在市场准入、审慎监管上给予创新,同时离不开经济政策的支持和金融技术法律的保障.

  19. Global Summit on Regulatory Science 2013.

    Science.gov (United States)

    Howard, Paul C; Tong, Weida; Weichold, Frank; Healy, Marion; Slikker, William

    2014-12-01

    Regulatory science has been defined as the science that is used to develop regulatory decisions by government bodies. Regulatory science encompasses many scientific disciplines that oversee many studies producing a wide array of data. These may include fundamental research into the cellular interaction or response to a particular chemical or substance, hazard-assessment and dose-response studies in animal species, neurophysiological or neurobehavioral studies, best practices for the generation and analysis of genomics data, bioinformatics approaches, and mathematical modeling of risk. The Global Summit on Regulatory Science is an international conference with a mission to explore emerging and innovative technologies, and provide a platform to enhance translation of basic science into regulatory applications. The Third Global Summit on Regulatory Science which focused on nanotechnology is discussed.

  20. Technology.

    Science.gov (United States)

    Online-Offline, 1998

    1998-01-01

    Focuses on technology, on advances in such areas as aeronautics, electronics, physics, the space sciences, as well as computers and the attendant progress in medicine, robotics, and artificial intelligence. Describes educational resources for elementary and middle school students, including Web sites, CD-ROMs and software, videotapes, books,…

  1. Consortium for Electric Reliability Technology Solutions Grid of the Future White Paper on Review of Recent Reliability Issues and Systems Events

    Energy Technology Data Exchange (ETDEWEB)

    Hauer, John F.; Dagle, Jeffery E.

    1999-12-01

    This report is one of six reports developed under the U.S. Department of Energy (DOE) program in Power System Integration and Reliability (PSIR). The objective of this report is to review, analyze, and evaluate critical reliability issues demonstrated by recent disturbance events in the North America power system. Eleven major disturbances are examined, most occurring in this decade. The strategic challenge is that the pattern of technical need has persisted for a long period of time. For more than a decade, anticipation of market deregulation has been a major disincentive to new investments in system capacity. It has also inspired reduced maintenance of existing assets. A massive infusion of better technology is emerging as the final option to continue reliable electrical services. If an investment in better technology will not be made in a timely manner, then North America should plan its adjustments to a very different level of electrical service. It is apparent that technical operations staff among the utilities can be very effective at marshaling their forces in the immediate aftermath of a system emergency, and that serious disturbances often lead to improved mechanisms for coordinated operation. It is not at all apparent that such efforts can be sustained through voluntary reliability organizations in which utility personnel external to those organizations do most of the technical work. The eastern interconnection shows several situations in which much of the technical support has migrated from the utilities to the Independent System Operator (ISO), and the ISO staffs or shares staff with the regional reliability council. This process may be a natural and very positive consequence of utility restructuring. If so, the process should be expedited in regions where it is less advanced.

  2. Genomics in the land of regulatory science.

    Science.gov (United States)

    Tong, Weida; Ostroff, Stephen; Blais, Burton; Silva, Primal; Dubuc, Martine; Healy, Marion; Slikker, William

    2015-06-01

    Genomics science has played a major role in the generation of new knowledge in the basic research arena, and currently question arises as to its potential to support regulatory processes. However, the integration of genomics in the regulatory decision-making process requires rigorous assessment and would benefit from consensus amongst international partners and research communities. To that end, the Global Coalition for Regulatory Science Research (GCRSR) hosted the fourth Global Summit on Regulatory Science (GSRS2014) to discuss the role of genomics in regulatory decision making, with a specific emphasis on applications in food safety and medical product development. Challenges and issues were discussed in the context of developing an international consensus for objective criteria in the analysis, interpretation and reporting of genomics data with an emphasis on transparency, traceability and "fitness for purpose" for the intended application. It was recognized that there is a need for a global path in the establishment of a regulatory bioinformatics framework for the development of transparent, reliable, reproducible and auditable processes in the management of food and medical product safety risks. It was also recognized that training is an important mechanism in achieving internationally consistent outcomes. GSRS2014 provided an effective venue for regulators andresearchers to meet, discuss common issues, and develop collaborations to address the challenges posed by the application of genomics to regulatory science, with the ultimate goal of wisely integrating novel technical innovations into regulatory decision-making.

  3. Digital Actuator Technology

    Energy Technology Data Exchange (ETDEWEB)

    Ken Thomas; Ted Quinn; Jerry Mauck; Richard Bockhorst

    2014-09-01

    There are significant developments underway in new types of actuators for power plant active components. Many of these make use of digital technology to provide a wide array of benefits in performance of the actuators and in reduced burden to maintain them. These new product offerings have gained considerable acceptance in use in process plants. In addition, they have been used in conventional power generation very successfully. This technology has been proven to deliver the benefits promised and substantiate the claims of improved performance. The nuclear industry has been reluctant to incorporate digital actuator technology into nuclear plant designs due to concerns due to a number of concerns. These could be summarized as cost, regulatory uncertainty, and a certain comfort factor with legacy analog technology. The replacement opportunity for these types of components represents a decision point for whether to invest in more modern technology that would provide superior operational and maintenance benefits. Yet, the application of digital technology has been problematic for the nuclear industry, due to qualification and regulatory issues. With some notable exceptions, the result has been a continuing reluctance to undertake the risks and uncertainties of implementing digital actuator technology when replacement opportunities present themselves. Rather, utilities would typically prefer to accept the performance limitations of the legacy analog actuator technologies to avoid impacts to project costs and schedules. The purpose of this report is to demonstrate that the benefits of digital actuator technology can be significant in terms of plant performance and that it is worthwhile to address the barriers currently holding back the widespread development and use of this technology. It addresses two important objectives in pursuit of the beneficial use of digital actuator technology for nuclear power plants: 1. To demonstrate the benefits of digital actuator

  4. Regulatory Expectations for Safety Culture

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Su Jin; Oh, Jang Jin; Choi, Young Sung [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-05-15

    The oversight of licensee's safety culture becomes an important issue that attracts great public and political concerns recently in Korea. Beginning from the intended violation of rules, a series of corruptions, documents forgery and disclosure of wrong-doings made the public think that the whole mindset of nuclear workers has been inadequate. Thus, they are demanding that safety culture shall be improved and that regulatory body shall play more roles and responsibilities for the improvements and oversight for them. This paper introduces, as an effort of regulatory side, recent changes in the role of regulators in safety culture, regulatory expectations on the desired status of licensee's safety culture, the pilot inspection program for safety culture and research activity for the development of oversight system. After the Fukushima accident in Japan 2011, many critics has searched for cultural factors that caused the unacceptable negligence pervaded in Japan nuclear society and the renewed emphasis has been placed on rebuilding safety culture by operators, regulators, and relevant institutions globally. Significant progress has been made in how to approach safety culture and led to a new perspective different from the existing normative assessment method both in operators and regulatory side. Regulatory expectations and oversight of them are based on such a new holistic concept for human, organizational and cultural elements to maintain and strengthen the integrity of defense in depth and consequently nuclear safety.

  5. SOCIO-ETHICAL ISSUES IN PERSONALIZED MEDICINE: A SYSTEMATIC REVIEW OF ENGLISH LANGUAGE HEALTH TECHNOLOGY ASSESSMENTS OF GENE EXPRESSION PROFILING TESTS FOR BREAST CANCER PROGNOSIS.

    Science.gov (United States)

    Ali-Khan, Sarah E; Black, Lee; Palmour, Nicole; Hallett, Michael T; Avard, Denise

    2015-01-01

    There have been multiple calls for explicit integration of ethical, legal, and social issues (ELSI) in health technology assessment (HTA) and addressing ELSI has been highlighted as key in optimizing benefits in the Omics/Personalized Medicine field. This study examines HTAs of an early clinical example of Personalized Medicine (gene expression profile tests [GEP] for breast cancer prognosis) aiming to: (i) identify ELSI; (ii) assess whether ELSIs are implicitly or explicitly addressed; and (iii) report methodology used for ELSI integration. A systematic search for HTAs (January 2004 to September 2012), followed by descriptive and qualitative content analysis. Seventeen HTAs for GEP were retrieved. Only three (18%) explicitly presented ELSI, and only one reported methodology. However, all of the HTAs included implicit ELSI. Eight themes of implicit and explicit ELSI were identified. "Classical" ELSI including privacy, informed consent, and concerns about limited patient/clinician genetic literacy were always presented explicitly. Some ELSI, including the need to understand how individual patients' risk tolerances affect clinical decision-making after reception of GEP results, were presented both explicitly and implicitly in HTAs. Others, such as concern about evidentiary deficiencies for clinical utility of GEP tests, occurred only implicitly. Despite a wide variety of important ELSI raised, these were rarely explicitly addressed in HTAs. Explicit treatment would increase their accessibility to decision-makers, and may augment HTA efficiency maximizing their utility. This is particularly important where complex Personalized Medicine applications are rapidly expanding choices for patients, clinicians and healthcare systems.

  6. Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?

    Science.gov (United States)

    Breyer, Didier; Herman, Philippe; Brandenburger, Annick; Gheysen, Godelieve; Remaut, Erik; Soumillion, Patrice; Van Doorsselaere, Jan; Custers, René; Pauwels, Katia; Sneyers, Myriam; Reheul, Dirk

    2009-01-01

    In the European Union, the definition of a GMO is technology-based. This means that a novel organism will be regulated under the GMO regulatory framework only if it has been developed with the use of defined techniques. This approach is now challenged with the emergence of new techniques. In this paper, we describe regulatory and safety issues associated with the use of oligonucleotide-mediated mutagenesis to develop novel organisms. We present scientific arguments for not having organisms developed through this technique fall within the scope of the EU regulation on GMOs. We conclude that any political decision on this issue should be taken on the basis of a broad reflection at EU level, while avoiding discrepancies at international level.

  7. Preserving the Environment of Outer Space - Legal, Regulatory and Institutional Aspects of Active Orbital Debris Removal

    Science.gov (United States)

    Mankata Nyampong, Y. O.

    2012-01-01

    In view of the massive quantities of space debris already deposited in outer space, any effort aimed at guaranteeing the sustainability of mankind's access to outer space and the continued safety of space operations must not be limited exclusively to mitigating the creation of new debris, but must also focus on the active removal of existing pieces of debris from space (remediation) as a matter of necessity. Presently, technologies that will enable active debris removal (ADR) are only just emerging. As the technology develops, however, several legal, regulatory and institutional issues that may hinder the conduct of ADR activities must also be addressed. This paper highlights and explores some of the foregoing issues in an effort to draw international attention to these matters and ultimately to pave the way for the smooth conduct of ADR activities once the technology matures.

  8. Technology

    Directory of Open Access Journals (Sweden)

    Xu Jing

    2016-01-01

    Full Text Available The traditional answer card reading method using OMR (Optical Mark Reader, most commonly, OMR special card special use, less versatile, high cost, aiming at the existing problems proposed a method based on pattern recognition of the answer card identification method. Using the method based on Line Segment Detector to detect the tilt of the image, the existence of tilt image rotation correction, and eventually achieve positioning and detection of answers to the answer sheet .Pattern recognition technology for automatic reading, high accuracy, detect faster

  9. Approaching ethical, legal and social issues of emerging forensic DNA phenotyping (FDP) technologies comprehensively: Reply to ‘Forensic DNA phenotyping: Predicting human appearance from crime scene material for investigative purposes’ by Manfred Kayser

    NARCIS (Netherlands)

    Toom, V.; Wienroth, M.; M'charek, A.; Prainsack, B.; Williams, R.; Duster, T.; Heinemann, T.; Kruse, C.; Machado, H.; Murphy, E.

    2016-01-01

    In a recent special issue of the journal on new trends in forensic genetics, Manfred Kayser contributed a review of developments, opportunities and challenges of forensic DNA phenotyping (FDP). In his article he argues that FDP technologies - such as determining eye, hair and skin color - should be

  10. Approaching ethical, legal and social issues of emerging forensic DNA phenotyping (FDP) technologies comprehensively: Reply to ‘Forensic DNA phenotyping: Predicting human appearance from crime scene material for investigative purposes’ by Manfred Kayser

    NARCIS (Netherlands)

    Toom, V.; Wienroth, M.; M'charek, A.; Prainsack, B.; Williams, R.; Duster, T.; Heinemann, T.; Kruse, C.; Machado, H.; Murphy, E.

    2016-01-01

    In a recent special issue of the journal on new trends in forensic genetics, Manfred Kayser contributed a review of developments, opportunities and challenges of forensic DNA phenotyping (FDP). In his article he argues that FDP technologies - such as determining eye, hair and skin color - should be

  11. The Political Economy of Regulatory Change

    DEFF Research Database (Denmark)

    Buch-Hansen, Hubert

    2012-01-01

    This article aims to explain the broader evolution of British merger control. To this end it outlines a novel critical political economy perspective on regulation and regulatory change which differs from established political economy approaches, such as the regulatory capitalism/state perspectives......, in three main ways: it places regulatory ideas at the heart of the analysis, it differentiates between different degrees of regulatory change, and it links regulatory change in delineated issue areas with changing power balances between fractions of capital and labor. The application of this perspective...... to the analysis of the evolution of British merger control provides some important new insights, most notably that the content, form, and scope of merger control in Britain have been deeply transformed in accordance with neoliberal ideas since the 1980s and that this process, which was part of a broader...

  12. Biofuels and regulatory framework: recent developments and key technological routes; Biocombustiveis e marco regulatorio: evolucao recente e as principais rotas tecnologicas

    Energy Technology Data Exchange (ETDEWEB)

    Berni, Mauro Donizeti [Universidade Estadual de Campinas (NIPE/UNICAMP), SP (Brazil). Nucleo Interdisciplinar de Planejamento Energetico], e-mail: mauro_berni@yahoo.com.br; Guerra, Sinclair M. Guy [Universidade Federal do ABC (CECS/UFABC), Santo Andre, SP (Brazil). Centro de Engenharia, Modelagem e Ciencias Sociais Aplicadas], e-mail: sguerra@ufabc.edu.br

    2008-07-01

    The excessive dependence of energy of the current societies, and the growing concern with the potentials associated climate change motivate the implementation of energy systems with base in resources of renewable energy. Climate change is the greatest environmental challenge the world is facing today. Rising global temperatures will bring changes in weather patterns, rising sea levels and increased frequency and intensity of extreme weather events. The effects will be felt here in Brazil; internationally there may be severe problems for people in regions that are particularly vulnerable. Brazil with experience in the bio fuels production can participate as a supplier of new technology for his production, at world level. This work, shows the recent evolution of the regulation for the bio fuels in Brazil, as well as their main ones routes technology, and it indicates the possible alternatives to guarantee the sustainability for the production and use. (author)

  13. The Platte River - High Plains Aquifer (PR-HPA) Long Term Agroecosystem Research (LTAR) Network - Data and Technological Resources to Address Current and Emerging Issues in Agroecosystems.

    Science.gov (United States)

    Okalebo, J. A.; Wienhold, B.; Suyker, A.; Erickson, G.; Hayes, M. J.; Awada, T.

    2015-12-01

    The Platte River - High Plains Aquifer (PR-HPA) is one of 18 established Long Term Agroecosystem Research (LTAR) networks across the US. PR-HPA is a partnership between the Institute of Agriculture and Natural Resources at the University of Nebraska-Lincoln (UNL), the USDA-ARS Agroecosystem Management Research Unit (AMRU) in Lincoln, and the USDA-ARS Environmental Management Research Unit (EMRU) in Clay Center, NE. The PR-HPA network encompasses 27,750 ha of research sites with data going back to the early 1900s. A partial list of on-going research projects include those encompassing long-term manuring and continuous corn (Est. 1912), dryland tillage plots (Est. 1970), soil nutrients and tillage (Est. 1983), biofuel feedstock studies (Est. 2001), and carbon sequestration study (Est. 2000). Affiliated partners include the National Drought Mitigation Center (NDMC) that develops measures to improve preparedness and adaptation to climate variability and drought; the High Plains Regional Climate Center (HPRCC) that coordinates data acquisition from over 170 automated weather stations and around 50 automated soil moisture network across NE and beyond; the AMERIFLUX and NEBFLUX networks that coordinate the water vapor and carbon dioxide flux measurements across NE with emphasis on rainfed and irrigated crop lands; the ARS Greenhouse gas Reduction through Agricultural Carbon Enhancement network (GRACEnet) and the Resilient Economic Agricultural Practices (REAP) project; and the Center for Advanced Land Management Information Technologies (CALMIT) that assists with the use of geospatial technologies for agriculture and natural resource applications. Current emphases are on addressing present-day and emerging issues related to profitability and sustainability of agroecosystems. The poster will highlight some of the ongoing and planned efforts in research pertaining to climate variability and change, water sustainability, and ecological and agronomic challenges associated

  14. Current issues with research support

    Energy Technology Data Exchange (ETDEWEB)

    Russell, W.T.

    1996-03-01

    It would be difficult to condense current issues in nuclear reactor regulation to just a few minutes. So, let me start off by saying that I have not tried to give a comprehensive listing of issues that are currently facing the reactor program, but rather to select those that I thought were relevant as they relate to research activities. Use of probabilistic risk assessment in regulatory decisions; materials aging issues concerning steam generators and reactor vessels; high burnup fuels; accident management; and digital instrumentation and control, are just a sampling of the important issues that I want to talk about.

  15. Symbiotic Nitrogen Fixation in Legume Nodules: Metabolism and Regulatory Mechanisms

    OpenAIRE

    Saad Sulieman; Lam-Son Phan Tran

    2014-01-01

    The special issue “Symbiotic Nitrogen Fixation in Legume Nodules: Metabolism and Regulatory Mechanisms” aims to investigate the physiological and biochemical advances in the symbiotic process with an emphasis on nodule establishment, development and functioning. The original research articles included in this issue provide important information regarding novel aspects of nodule metabolism and various regulatory pathways, which could have important future implications. This issue also included...

  16. Impact of human genome initiative-derived technology on genetic testing, screening and counseling: Cultural, ethical and legal issues. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Trottier, R.W.; Hodgin, F.C.; Imara, M.; Phoenix, D.; Lybrook, S. [Morehouse Coll., Atlanta, GA (United States). School of Medicine; Crandall, L.A.; Moseley, R.E.; Armotrading, D. [Florida Univ., Gainesville, FL (United States). Coll. of Medicine

    1993-03-01

    Genetic medical services provided by the Georgia Division of Public Health in two northern and two central districts are compared to services provided in a district in which a tertiary care facility is located. Genetics outreach public health nurses play key roles in Georgia`s system of Children`s Health Services Genetics Program, including significant roles as counselors and information sources on special needs social services and support organizations. Unique features of individual health districts, (e.g., the changing face of some rural communities in ethnocultural diversity and socioeconomic character), present new challenges to current and future genetics services delivery. Preparedness as to educational needs of both health professionals and the lay population is of foremost concern in light of the ever expanding knowledge and technology in medical genetics. Perspectives on genetics and an overview of services offered by a local private sector counselor are included for comparison to state supported services. The nature of the interactions which transpire between private and public genetic services resources in Georgia will be described. A special focus of this research includes issues associated with sickle cell disease newborn screening service delivery process in Georgia, with particular attention paid to patient follow-up and transition to primary care. Of particular interest to this focus is the problem of loss to follow-up in the current system. Critical factors in education and counseling of sickle cell patients and the expectations of expanding roles of primary care physicians are discussed. The Florida approach to the delivery of genetic services contrasts to the Georgia model by placing more emphasis on a consultant-specialist team approach.

  17. KWOC (Key-Word-Out-of-Context) Index of US Nuclear Regulatory Commission Regulatory Guide Series

    Energy Technology Data Exchange (ETDEWEB)

    Jennings, S.D.

    1990-04-01

    To meet the objectives of the program funded by the Department of Energy (DOE)-Nuclear Energy (NE) Technology Support Programs, the Performance Assurance Project Office (PAPO) administers a Performance Assurance Information Program that collects, compiles, and distributes program-related information, reports, and publications for the benefit of the DOE-NE program participants. THE KWOC Index of US Nuclear Regulatory Commission Regulatory Guide Series'' is prepared as an aid in searching for specific topics in the US Nuclear Regulatory Commission, Regulatory Guide Series.

  18. The Design of Technology-Rich Learning Environments as Metacognitive Tools in History Education

    Science.gov (United States)

    Poitras, Eric; Lajoie, Susanne; Hong, Yuan-Jin

    2012-01-01

    Research has shown that learners do not always engage in appropriate metacognitive and self-regulatory processes while learning complex historical topics. However, little research exists to guide the design of technology-rich learning environments as metacognitive tools in history education. In order to address this issue, we designed a…

  19. 75 FR 62892 - Massachusetts Institute of Technology Research Reactor Environmental Assessment and Finding of No...

    Science.gov (United States)

    2010-10-13

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Massachusetts Institute of Technology Research Reactor Environmental Assessment and Finding of No Significant Impact Correction In notice document 2010-24809 beginning on page 61220 in the issue of...

  20. Regulatory considerations for biosimilars

    Directory of Open Access Journals (Sweden)

    Ranjani Nellore

    2010-01-01

    Full Text Available Currently there is considerable interest in the legislative debate around generic biological drugs or "biosimilars" in the EU and US due to the large, lucrative market that it offers to the industry. While some countries have issued a few regulatory guidelines as well as product specific requirements, there is no general consensus as to a single, simple mechanism similar to the bioequivalence determination that leads to approval of generic small molecules all over the world. The inherent complex nature of the molecules, along with complicated manufacturing and analytical techniques to characterize them make it difficult to rely on a single human pharmacokinetic study for assurance of safety and efficacy. In general, the concept of comparability has been used for evaluation of the currently approved "similar" biological where a step by step assessment on the quality, preclinical and clinical aspects is made. In India, the focus is primarily on the availability and affordability of life-saving drugs. In this context every product needs to be evaluated on its own merit irrespective of the innovator brand. The formation of the National Biotechnology Regulatory Authority may provide a step in the right direction for regulation of these complex molecules. However, in order to have an efficient machinery for initial approval and ongoing oversight with a country-specific focus, cooperation with international authorities for granting approvals and continuous risk-benefit review is essential. Several steps are still needed for India to be perceived as a country that leads the world in providing quality biological products.

  1. Regulatory and technical reports (abstract index journal): Annual compilation for 1996, Volume 21, No. 4

    Energy Technology Data Exchange (ETDEWEB)

    Sheehan, M.A.

    1997-04-01

    This compilation is the annual cumulation of bibliographic data and abstracts for the formal regulatory and technical reports issued by the U.S. Nuclear Regulatory Commission (NRC) Staff and its contractors.

  2. 76 FR 72220 - Incorporation of Risk Management Concepts in Regulatory Programs

    Science.gov (United States)

    2011-11-22

    ... COMMISSION Incorporation of Risk Management Concepts in Regulatory Programs AGENCY: Nuclear Regulatory... Commission) is considering development of a strategic vision to better incorporate risk management concepts... homeland security issues, the task force ] believes that risk management concepts may represent a...

  3. Information on new drugs at market entry: retrospective analysis of health technology assessment reports versus regulatory reports, journal publications, and registry reports

    Science.gov (United States)

    Köhler, Michael; Haag, Susanne; Biester, Katharina; Brockhaus, Anne Catharina; McGauran, Natalie; Grouven, Ulrich; Kölsch, Heike; Seay, Ulrike; Hörn, Helmut; Moritz, Gregor; Staeck, Kerstin

    2015-01-01

    Background When a new drug becomes available, patients and doctors require information on its benefits and harms. In 2011, Germany introduced the early benefit assessment of new drugs through the act on the reform of the market for medicinal products (AMNOG). At market entry, the pharmaceutical company responsible must submit a standardised dossier containing all available evidence of the drug’s added benefit over an appropriate comparator treatment. The added benefit is mainly determined using patient relevant outcomes. The “dossier assessment” is generally performed by the Institute for Quality and Efficiency in Health Care (IQWiG) and then published online. It contains all relevant study information, including data from unpublished clinical study reports contained in the dossiers. The dossier assessment refers to the patient population for which the new drug is approved according to the summary of product characteristics. This patient population may comprise either the total populations investigated in the studies submitted to regulatory authorities in the drug approval process, or the specific subpopulations defined in the summary of product characteristics (“approved subpopulations”). Objective To determine the information gain from AMNOG documents compared with non-AMNOG documents for methods and results of studies available at market entry of new drugs. AMNOG documents comprise dossier assessments done by IQWiG and publicly available modules of company dossiers; non-AMNOG documents comprise conventional, publicly available sources—that is, European public assessment reports, journal publications, and registry reports. The analysis focused on the approved patient populations. Design Retrospective analysis. Data sources All dossier assessments conducted by IQWiG between 1 January 2011 and 28 February 2013 in which the dossiers contained suitable studies allowing for a full early benefit assessment. We also considered all European public assessment

  4. Due diligence issues report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-05-01

    The administrative and regulatory issues associated with offshore oil and gas exploration and development in British Columbia were discussed with reference to the creation of a management framework that would ensure that resource development occurs in a socially responsible manner. Provincial governments have jurisdiction over resource management, including intra-provincial trade, commerce and environmental issues within their borders. The federal government has control over resources, subsoil and the seabed out to 200 miles beyond the baseline. The federal government also regulates Frontier Lands, which are divided into Non-Accord and Accord areas. In Accord areas such as Newfoundland and Nova Scotia, oil and gas development is managed by the respective Offshore Petroleum Board. Currently, the British Columbia offshore is a Non-Accord area subject to the administration of Federal legislation. Environmental and regulatory issues were also discussed, along with regional equity, benefits planning, equity versus efficiency, proactivity, and public consultation. It was concluded that there is no scientific, technical or environmental barriers that would prevent the socially responsible development of British Columbia's offshore. There is also much evidence from other jurisdictions that indicates that British Columbia and Canada would benefit from prudent development of offshore oil and gas resources. refs., tabs., figs.

  5. Teaching Ethical Reflexivity in Information Systems: How to Equip Students to Deal with Moral and Ethical Issues of Emerging Information and Communication Technologies

    Science.gov (United States)

    Stahl, Bernd Carsten

    2011-01-01

    Teaching ethics to students of information systems (IS) raises a number of conceptual and content-related issues. The present paper starts out by developing a conceptual framework of moral and ethical issues that distinguishes between moral intuition, explicit morality, ethical theory and meta-ethical reflection. This conceptual framework…

  6. Contemporary issues in transfusion medicine informatics

    Directory of Open Access Journals (Sweden)

    Gaurav Sharma

    2011-01-01

    Full Text Available The Transfusion Medicine Service (TMS covers diverse clinical and laboratory-based services that must be delivered with accuracy, efficiency and reliability. TMS oversight is shared by multiple regulatory agencies that cover product manufacturing and validation standards geared toward patient safety. These demands present significant informatics challenges. Over the past few decades, TMS information systems have improved to better handle blood product manufacturing, inventory, delivery, tracking and documentation. Audit trails and access to electronic databases have greatly facilitated product traceability and biovigilance efforts. Modern blood bank computing has enabled novel applications such as the electronic crossmatch, kiosk-based blood product delivery systems, and self-administered computerized blood donor interview and eligibility determination. With increasing use of barcoding technology, there has been a marked improvement in patient and specimen identification. Moreover, the emergence of national and international labeling standards such as ISBT 128 have facilitated the availability, movement and tracking of blood products across national and international boundaries. TMS has only recently begun to leverage the electronic medical record to address quality issues in transfusion practice and promote standardized documentation within institutions. With improved technology, future growth is expected in blood bank automation and product labeling with applications such as radio frequency identification devices. This article reviews several of these key informatics issues relevant to the contemporary practice of TMS.

  7. Contemporary issues in transfusion medicine informatics

    Science.gov (United States)

    Sharma, Gaurav; Parwani, Anil V.; Raval, Jay S.; Triulzi, Darrell J.; Benjamin, Richard J.; Pantanowitz, Liron

    2011-01-01

    The Transfusion Medicine Service (TMS) covers diverse clinical and laboratory-based services that must be delivered with accuracy, efficiency and reliability. TMS oversight is shared by multiple regulatory agencies that cover product manufacturing and validation standards geared toward patient safety. These demands present significant informatics challenges. Over the past few decades, TMS information systems have improved to better handle blood product manufacturing, inventory, delivery, tracking and documentation. Audit trails and access to electronic databases have greatly facilitated product traceability and biovigilance efforts. Modern blood bank computing has enabled novel applications such as the electronic crossmatch, kiosk-based blood product delivery systems, and self-administered computerized blood donor interview and eligibility determination. With increasing use of barcoding technology, there has been a marked improvement in patient and specimen identification. Moreover, the emergence of national and international labeling standards such as ISBT 128 have facilitated the availability, movement and tracking of blood products across national and international boundaries. TMS has only recently begun to leverage the electronic medical record to address quality issues in transfusion practice and promote standardized documentation within institutions. With improved technology, future growth is expected in blood bank automation and product labeling with applications such as radio frequency identification devices. This article reviews several of these key informatics issues relevant to the contemporary practice of TMS. PMID:21383927

  8. Exploring the application of an evolutionary educational complex systems framework to teaching and learning about issues in the science and technology classroom

    Science.gov (United States)

    Yoon, Susan Anne

    Understanding the world through a complex systems lens has recently garnered a great deal of interest in many knowledge disciplines. In the educational arena, interactional studies, through their focus on understanding patterns of system behaviour including the dynamical processes and trajectories of learning, lend support for investigating how a complex systems approach can inform educational research. This study uses previously existing literature and tools for complex systems applications and seeks to extend this research base by exploring learning outcomes of a complex systems framework when applied to curriculum and instruction. It is argued that by applying the evolutionary dynamics of variation, interaction and selection, complexity may be harnessed to achieve growth in both the social and cognitive systems of the classroom. Furthermore, if the goal of education, i.e., the social system under investigation, is to teach for understanding, conceptual knowledge of the kind described in Popper's (1972; 1976) World 3, needs to evolve. Both the study of memetic processes and knowledge building pioneered by Bereiter (cf. Bereiter, 2002) draw on the World 3 notion of ideas existing as conceptual artifacts that can be investigated as products outside of the individual mind providing an educational lens from which to proceed. The curricular topic addressed is the development of an ethical understanding of the scientific and technological issues of genetic engineering. 11 grade 8 students are studied as they proceed through 40 hours of curricular instruction based on the complex systems evolutionary framework. Results demonstrate growth in both complex systems thinking and content knowledge of the topic of genetic engineering. Several memetic processes are hypothesized to have influenced how and why ideas change. Categorized by factors influencing either reflective or non-reflective selection, these processes appear to have exerted differential effects on students

  9. Advanced Reactor Licensing: Experience with Digital I&C Technology in Evolutionary Plants

    Energy Technology Data Exchange (ETDEWEB)

    Wood, RT

    2004-09-27

    This report presents the findings from a study of experience with digital instrumentation and controls (I&C) technology in evolutionary nuclear power plants. In particular, this study evaluated regulatory approaches employed by the international nuclear power community for licensing advanced l&C systems and identified lessons learned. The report (1) gives an overview of the modern l&C technologies employed at numerous evolutionary nuclear power plants, (2) identifies performance experience derived from those applications, (3) discusses regulatory processes employed and issues that have arisen, (4) captures lessons learned from performance and regulatory experience, (5) suggests anticipated issues that may arise from international near-term deployment of reactor concepts, and (6) offers conclusions and recommendations for potential activities to support advanced reactor licensing in the United States.

  10. Emerging technology: A key enabler for modernizing pharmaceutical manufacturing and advancing product quality.

    Science.gov (United States)

    O'Connor, Thomas F; Yu, Lawrence X; Lee, Sau L

    2016-07-25

    Issues in product quality have produced recalls and caused drug shortages in United States (U.S.) in the past few years. These quality issues were often due to outdated manufacturing technologies and equipment as well as lack of an effective quality management system. To ensure consistent supply of safe, effective and high-quality drug products available to the patients, the U.S. Food and Drug Administration (FDA) supports modernizing pharmaceutical manufacturing for improvements in product quality. Specifically, five new initiatives are proposed here to achieve this goal. They include: (i) advancing regulatory science for pharmaceutical manufacturing; (ii) establishing a public-private institute for pharmaceutical manufacturing innovation; (iii) creating incentives for investment in the technological upgrade of manufacturing processes and facilities; (iv) leveraging external expertise for regulatory quality assessment of emerging technologies; and (v) promoting the international harmonization of approaches for expediting the global adoption of emerging technologies.

  11. Wireless ATM : handover issues

    OpenAIRE

    Jiang, Fan; Käkölä, Timo

    1998-01-01

    Basic aspects of cellular systems and the ATM transmission technology are introduced. Wireless ATM is presented as a combination of radio ATM and mobile ATM. Radio ATM is a wireless extension of an ATM connection while mobile ATM contains the necessary extensions to ATM to support mobility. Because the current ATM technology does not support mobility, handover becomes one of the most important research issues for wireless ATM. Wireless ATM handover requirements are thus analysed. A handover s...

  12. Talking on the Characteristics of P2P Technology and Network Security Issues%论P2P技术特点与网络安全问题

    Institute of Scientific and Technical Information of China (English)

    钱利剑

    2011-01-01

    P2P technology has been developing quite fast,widely used in a variety of network activity, but there are many security issues of P2P technology.This author primarily on P2P network security analysis and discussion.%P2P技术近年来发展得相当快,广泛应用各种网络活动中,但目前P2P技术存在诸多安全问题。本文笔者主要对P2P网络安全问题进行分析与探讨。

  13. Excess plutonium disposition using ALWR technology

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, A. (ed.); Buckner, M.R.; Radder, J.A.; Angelos, J.G.; Inhaber, H.

    1993-02-01

    The Office of Nuclear Energy of the Department of Energy chartered the Plutonium Disposition Task Force in August 1992. The Task Force was created to assess the range of practicable means of disposition of excess weapons-grade plutonium. Within the Task Force, working groups were formed to consider: (1) storage, (2) disposal,and(3) fission options for this disposition,and a separate group to evaluate nonproliferation concerns of each of the alternatives. As a member of the Fission Working Group, the Savannah River Technology Center acted as a sponsor for light water reactor (LWR) technology. The information contained in this report details the submittal that was made to the Fission Working Group of the technical assessment of LWR technology for plutonium disposition. The following aspects were considered: (1) proliferation issues, (2) technical feasibility, (3) technical availability, (4) economics, (5) regulatory issues, and (6) political acceptance.

  14. Inter-institutional decision making in the technology transfer process: Some preliminary issues in the evaluation of ORNL's High-Temperature Superconductivity Pilot Center

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, D.L.

    1989-09-01

    This report illuminates the decision-making processes affecting technology transfer at ORNL as they potentially impact upon development of high-temperature superconductors. The methodology of this report consists of an analysis of Oak Ridge National Laboratory (ORNL) documents laws, and regulations; a review of relevant literature on licensing, patents, and user center decision making; and interviews with persons directly involved in technology development and transfer at the laboratory. The process of technology development at ORNL encompasses, among other things, activities aimed at research and development (R D), technology transfer, and technology utilization. Each of these activities has officially become part of an overall laboratory mission referred to as technology development. 28 refs., 1 fig., 3 tabs.

  15. Regulatory Streamlining and Improvement

    Energy Technology Data Exchange (ETDEWEB)

    Mark A. Carl

    2006-07-11

    The Interstate Oil and Gas Compact Commission (IOGCC) engaged in numerous projects outlined under the scope of work discussed in the United States Department of Energy (DOE) grant number DE-FC26-04NT15456 awarded to the IOGCC. Numerous projects were completed that were extremely valuable to state oil and gas agencies as a result of work performed utilizing resources provided by the grant. There are numerous areas in which state agencies still need assistance. This additional assistance will need to be addressed under future scopes of work submitted annually to DOE's Project Officer for this grant. This report discusses the progress of the projects outlined under the grant scope of work for the 2005-2006 areas of interest, which are as follows: Area of Interest No. 1--Regulatory Streamlining and Improvement: This area of interest continues to support IOGCC's regulatory streamlining efforts that include the identification and elimination of unnecessary duplications of efforts between and among state and federal programs dealing with exploration and production on public lands. Area of Interest No. 2--Technology: This area of interest seeks to improve efficiency in states through the identification of technologies that can reduce costs. Area of Interest No. 3--Training and Education: This area of interest is vital to upgrading the skills of regulators and industry alike. Within the National Energy Policy, there are many appropriate training and education opportunities. Education was strongly endorsed by the President's National Energy Policy Development group. Acting through the governors offices, states are very effective conduits for the dissemination of energy education information. While the IOGCC favors the development of a comprehensive, long-term energy education plan, states are also supportive of immediate action on important concerns, such as energy prices, availability and conservation. Area of Interest No. 4--Resource Assessment and

  16. Women's Issues Are Economic Issues.

    Science.gov (United States)

    Schroeder, Patricia

    1983-01-01

    Faulty laws, unfair practices, and years of tradition in the workplace keep women from economic equality. The Economic Equity Act proposed by Congress will address inequalities in tax and retirement matters, the need for better dependent care, nondiscrimination in insurance, regulatory reform, and child support enforcement. (IS)

  17. Irregular Warfare and Future War: Strategy and Defense Planning; Strategic Insights, v. 10, Special issue (October 2011), 92-98. Topic: Global Trends and Future Warfare ; Part II: Technological and Doctrinal Innovation

    OpenAIRE

    Russell, James A.

    2011-01-01

    This article appeared in Strategic Insights, v.10, Special issue (October 2011), 92-98. Topic: Global Trends and Future Warfare ; Part II: Technological and Doctrinal Innovation Approved for public display, distribution unlimited The purpose of this paper is threefold: to speculate on the role and prominence of irregular warfare in the strategic environment over the next quarter century, to comment on the impact that phenomenon may have on shaping the postulated scenarios addressed in t...

  18. Approaching ethical, legal and social issues of emerging forensic DNA phenotyping (FDP) technologies comprehensively: Reply to ‘Forensic DNA phenotyping: Predicting human appearance from crime scene material for investigative purposes’ by Manfred Kayser

    OpenAIRE

    Toom, V.; Wienroth, M.; M'Charek, A.; Prainsack, B.; Williams, R.; Duster, T.; Heinemann, T.; C. Kruse; Machado, H; Murphy, E.

    2016-01-01

    In a recent special issue of the journal on new trends in forensic genetics, Manfred Kayser contributed a review of developments, opportunities and challenges of forensic DNA phenotyping (FDP). In his article he argues that FDP technologies - such as determining eye, hair and skin color - should be considered as akin to a "biological witness" with the potential of providing more accurate information than traditional eye witnesses.

  19. Regulatory analysis technical evaluation handbook. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The purpose of this Handbook is to provide guidance to the regulatory analyst to promote preparation of quality regulatory analysis documents and to implement the policies of the Regulatory Analysis Guidelines of the US Nuclear Regulatory Commission (NUREG/BR-0058 Rev. 2). This Handbook expands upon policy concepts included in the NRC Guidelines and translates the six steps in preparing regulatory analyses into implementable methodologies for the analyst. It provides standardized methods of preparation and presentation of regulatory analyses, with the inclusion of input that will satisfy all backfit requirements and requirements of NRC`s Committee to Review Generic Requirements. Information on the objectives of the safety goal evaluation process and potential data sources for preparing a safety goal evaluation is also included. Consistent application of the methods provided here will result in more directly comparable analyses, thus aiding decision-makers in evaluating and comparing various regulatory actions. The handbook is being issued in loose-leaf format to facilitate revisions. NRC intends to periodically revise the handbook as new and improved guidance, data, and methods become available.

  20. Information Technologies in Teacher Education. Issues and Experiences for Countries in Transition. Proceedings of a European Workshop, University of Twente (Enschede, Netherlands, February 20-23, 1994).

    Science.gov (United States)

    Collis, Betty, Ed.; And Others

    This document contains 21 papers from an international workshop designed to facilitate the exchange of ideas concerning the use of information technology in teacher education among experts from Central, Eastern, and Western Europe. The papers include: (1) "Communication and Information Technologies as Change Agents" (Jef Moonen); (2)…