WorldWideScience

Sample records for technologically-mediated interactive art

  1. Communicating Art through Interactive Technology: New Approaches for Interaction Design in Art Museums

    DEFF Research Database (Denmark)

    Kortbek, Karen Johanne; Grønbæk, Kaj

    2008-01-01

    This paper discusses new approaches to interaction design for communication of art in the physical museum space. In contrast to the widespread utilization of interactive tech­nologies in cultural heritage and natural science museums it is generally a challenge to introduce technology in art museums...... without disturbing the domain of the art works. To explore the possibilities of communicating art through the use of technology, and to minimize disturbance of the artworks, we apply four main approaches in the communication: 1) gentle audio augmentation of art works; 2) conceptual affinity of art works...... and remote interactive installations; 3) using the body as an interaction device; 4) consistent audio-visual cues for interaction opportunities. The paper describes the application of these approaches for communication of inspira­tional material for a Mariko Mori exhibition. The installations are described...

  2. Arts and Technology

    DEFF Research Database (Denmark)

    This book constitutes the thoroughly refereed post-conference proceedings of the Second International Conference on Arts and Technology, ArtsIT 2011, which was held in December 2011 in Esbjerg, Denmark. The 19 revised full papers and the two poster papers cover various topics such as Interaction...... and Art, Music and Performance, and Digital Technology....

  3. Communication Solutions by Improving Interactive Art Projects

    Directory of Open Access Journals (Sweden)

    Gintarė Vainalavičiūtė

    2016-03-01

    Full Text Available The article examines the emergence of new forms of expression in modern society such as technology, which makes the traditional art active and the users are drawn into the processes of creation and dissemination. Interactive art technology gradually integrates more and more people to be interested on it because of its innovative and interesting concept and idea. Interactive art removes traditional boundaries between the artist and “public”. Appearance of the new modern technologies in the art provoked the development of the interactive art which later evolved into some other forms of art as cinema, interactive dance, music and etc. The article is based on Lithuanian and foreign academic works, interactive art definition is provided the theoretical aspect of an interactive art projects is highlighted. The modern theories of marketing communications are defined. To solve examined issues marketing communication model with highlighted key elements is proposed.

  4. Interactive Technologies in Musical and Arts Education

    Directory of Open Access Journals (Sweden)

    Y. Y. Glazyrina

    2013-01-01

    Full Text Available The paper substantiates the introduction of interactive techniques in music and arts education, and analyzes the definitions of interactivity – a key term of the modern educational paradigm. Various interpretationsof interactivity and its components – interaction, communication, dia logue, polylogue, interpretation, reinterpretation, intonation, feelings, comprehension, generalization (reflection, and experience – are given. In the methodology context, the author traces out the similarity of interactive concepts in general didactics and the humanities knowledge (M. M. Bakhtin, V. S. Bibler, and maintains that the main components of interactive teaching include the basic categories of culture, art, music, and psychology of artistic perception and creativity. Therefore, similarity of the content and approach to interpreting the conceptual terminological apparatus of interactive education makes it possible to implement the interactive techniques in teaching the cycle of music and arts disciplines.

  5. Technology in Art Therapy: Ethical Challenges

    Science.gov (United States)

    Alders, Amanda; Beck, Liz; Allen, Pat B.; Mosinski, Barbara

    2011-01-01

    As technology advances, art therapy practices are adapting to the demands of a new cultural climate. Art therapists face a number of ethical challenges as they interact with increasingly diverse populations and employ new media. This article addresses some of the ethical and professional issues related to the use of technology in clinical…

  6. Art Therapists' Emotional Reactions to the Demands of Technology

    Science.gov (United States)

    Asawa, Paige

    2009-01-01

    Art therapists increasingly are turning to educational and presentation technology to expand awareness of their field and to inform others in mental health care. This trend supports inquiry into how art therapists interact with and emotionally respond to the demands of technology. This paper presents a qualitative study that used 3 art-based focus…

  7. Art, Technology and Nature

    DEFF Research Database (Denmark)

    Camilla Skovbjerg Paldam and Jacob Wamberg trace the Kantian heritage of radically separating art and technology, and inserting both at a distance to nature, suggesting this was a transient chapter in history. Thus, they argue, the present renegotiation between art, technology and nature is reminiscent......Since 1900, the connections between art and technology with nature have become increasingly inextricable. Through a selection of innovative readings by international scholars, this book presents the first investigation of the intersections between art, technology and nature in post-medieval times....... Transdisciplinary in approach, this volume’s 14 essays explore art, technology and nature’s shifting constellations that are discernible at the micro level and as part of a larger chronological pattern. Included are subjects ranging from Renaissance wooden dolls, science in the Italian art academies, and artisanal...

  8. Art-Science-Technology collaboration through immersive, interactive 3D visualization

    Science.gov (United States)

    Kellogg, L. H.

    2014-12-01

    At the W. M. Keck Center for Active Visualization in Earth Sciences (KeckCAVES), a group of geoscientists and computer scientists collaborate to develop and use of interactive, immersive, 3D visualization technology to view, manipulate, and interpret data for scientific research. The visual impact of immersion in a CAVE environment can be extremely compelling, and from the outset KeckCAVES scientists have collaborated with artists to bring this technology to creative works, including theater and dance performance, installations, and gamification. The first full-fledged collaboration designed and produced a performance called "Collapse: Suddenly falling down", choreographed by Della Davidson, which investigated the human and cultural response to natural and man-made disasters. Scientific data (lidar scans of disaster sites, such as landslides and mine collapses) were fully integrated into the performance by the Sideshow Physical Theatre. This presentation will discuss both the technological and creative characteristics of, and lessons learned from the collaboration. Many parallels between the artistic and scientific process emerged. We observed that both artists and scientists set out to investigate a topic, solve a problem, or answer a question. Refining that question or problem is an essential part of both the creative and scientific workflow. Both artists and scientists seek understanding (in this case understanding of natural disasters). Differences also emerged; the group noted that the scientists sought clarity (including but not limited to quantitative measurements) as a means to understanding, while the artists embraced ambiguity, also as a means to understanding. Subsequent art-science-technology collaborations have responded to evolving technology for visualization and include gamification as a means to explore data, and use of augmented reality for informal learning in museum settings.

  9. The Status of Interactivity in Computer Art: Formal Apories

    Directory of Open Access Journals (Sweden)

    João Castro Pinto

    2011-12-01

    Full Text Available Contemporary art, particularly that which is produced by computer technologies capable of receiving data input via interactive devices (sensors and controllers, constitutes an emerging expressive medium of interdisciplinary nature, which implies the need for a critical look at its constitution and artistic functions. To consider interactive art as a form of artistic expression that files under the present categorization, implies the acceptance of the participation of the spectator in the production of the work of art, supposedly at the time of its origin / or during its creation. When we examine the significance of the formal status of interactivity, assuming as a theoretical starting point the referred premises and reducing it to a phenomenological point of view of artistic creation, we quickly fall into difficulties of conceptual definitions and structural apories [1]. The fundamental aim of this research is to formally define the status of interactive art, by perpetrating a phenomenological examination on the creative process of this specific art, establishing crucial distinctions in order to develop a hermeneutics in favor of creation of new perspectives and aesthetic frameworks. What is interactive creation? Is interactivity, from the computing artistic creativity point of view, the exponentiation of the concept of the open work of art (ECO 2009? Does interactive art correspond to an a priori projective and unachievable meta-art? What is the status of the artist and of the spectator in relation to an interactive work of art? What ontic and factical conditions are postulated as necessary in order to determine an artistic product as co-created? What apories do we find along the progres- sive process of reaching to a clarifying conceptual definition?This brief investigation will seek to contribute to the study of this issue, intending ultimately, and above all, to expose pertinent lines of inquiry rather than to provide definite scientific and

  10. CyberArts Showcase features artistic exploration of CAVE technology, live web cast

    OpenAIRE

    Watson-Bloch, Cathy

    2005-01-01

    Experience a 21st-century exploration of the place where art and science/technology meet, where reality and cyber worlds collide. The CyberArts Showcase, an innovative, virtual art museum of student works that uses technology to create inventive, interactive worlds of digital art, will be held from 5 p.m. to 8 p.m. on Friday, April 15, at Torgersen Hall on Virginia Tech's campus. Roberto Bocci, multimedia artist and professor of digital art at Georgetown University will open the event.

  11. Technology transfer present and futures in the electronic arts

    Directory of Open Access Journals (Sweden)

    Brian Degger

    2008-01-01

    Full Text Available We are entering an era where creating the fantastical is possible in the arts. In the areas of mixed reality and biological arts, responsive works are created based on advances in basic science and technology. This is enabling scientists and artists to pose new questions. As the time between discovery and application is so short, artists need imaginative ways of accessing new technology in order to critique and use it.These are the new paints that the majority of artists cannot afford or access, technology to enable cloning of DNA, to print channels on a chip, to access proprietary 3G networks. Currently, partnerships or residencies are used to facilitate artist’s access to these technologies. What would they do if technology was available that enabled them to make any art work they so desire? Are the limitations in current technology an advantage rather than a disadvantage in some of their works? Does interaction with technologists make their work more robust? Are there disadvantages? How do they get access to the technology they require? Open source or proprietary? Or have they encountered the situation where their vision is greater than technology allows. When their work breaks because of this fact, is their art broken? Blast Theory (Brighton,UK, FoAM(Brussels, Belgium and Amsterdam, Netherlands, SymbioticA (Perth, Australia are organisations pushing technological boundaries in the service of art. This paper addresses some questions of technology transfer in relation to recent artworks, particularly I like Frank in Adelaide (Blast Theory, transient reality generators (trg (FoAM and Multi electrode array artist (MeART (SymbioticA.

  12. Art technologies as possible propulsars in technological innovation

    DEFF Research Database (Denmark)

    Jørgensen, Lars Botin

    2003-01-01

    kind. This discussion, of general character, constitutes the initial part of this paper. Then it briefly looks into the final terms of the papertitle and try to relate to the diffuse and discussed technological innovation. Both aspects – art and technology and technological innovation – will be dealt...... with from a historical/hermeneutic and social constructivist point of view, as the paper moves from a general principal level to a more specific, exemplary level, where three different art technologies are presented as possible propulsars in technological innovation.......Art and technology has, as the German philosopher Martin Heidegger points out, the same etymological root. A thorough investigation of the relationship between art and technology will show how this same root has manifested itself in different times and spaces bringing results of the most variegated...

  13. Interactivity, from art to surgery to space!

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    Currently the way we interact with computers can be done much more naturally with touchless technologies powered by new hardware and computer vision. A good example is the Microsoft Kinect, that changed not only the way we can play games at our homes but also how we can experiment a work of art. I am presenting some of these technologies and what they can be used for, in the hope that there might be use cases at CERN that could use these solutions.

  14. Technology-Use Mediation

    DEFF Research Database (Denmark)

    Bansler, Jørgen P.; Havn, Erling C.

    2003-01-01

    This study analyzes how a group of ‘mediators’ in a large, multinational company adapted a computer-mediated communication technology (a ‘virtual workspace’) to the organizational context (and vice versa) by modifying features of the technology, providing ongoing support for users, and promoting...... appropriate conventions of use. Our findings corroborate earlier research on technology-use mediation, which suggests that such mediators can exert considerable influence on how a particular technology will be established and used in an organization. However, this study also indicates that the process...... of technology-use mediation is more complex and indeterminate than earlier literature suggests. In particular, we want to draw attention to the fact that advanced computer-mediated communication technologies are equivocal and that technology-use mediation consequently requires ongoing sensemaking (Weick 1995)....

  15. Material interaction and art product in art therapy assessment in adult mental health

    NARCIS (Netherlands)

    Pénzes, I.J.N.J.; Hooren, S. van; Dokter, D.; Smeijsters, H.; Hutschemaekers, G.J.M.

    2016-01-01

    Background: Art materials have a central role in art therapy. The way a client interacts with art materials - material interaction - is an important source of information in art therapy assessment in adult mental health. The aim of this study was to develop the categories of material interaction and

  16. Technology Education and the Arts

    Science.gov (United States)

    Roman, Harry T.

    2009-01-01

    One hears quite frequently how the arts continually suffer in the academic day. Many long-time technology education champions certainly know what this is all about; but there may be some ways to use technology education to bring the arts into the classroom. This article offers a series of activities and suggestions that will help students better…

  17. Technology-Use Mediation

    DEFF Research Database (Denmark)

    Bansler, Jørgen P.; Havn, Erling C.

    2004-01-01

    Implementation of new computer-mediated communication (CMC) systems in organizations is a complex socio-technical endeavour, involving the mutual adaptation of technology and organization over time. Drawing on the analytic concept of sensemaking, this paper provides a theoretical perspective...... that deepens our understanding of how organizations appropriate new electronic communication media. The paper analyzes how a group of mediators in a large, multinational company adapted a new web-based CMC technology (a virtual workspace) to the local organizational context (and vice versa) by modifying...... features of the technology, providing ongoing support for users, and promoting appropriate conventions of use. We found that these mediators exerted considerable influence on how the technology was established and used in the organization. The mediators were not neutral facilitators of a well...

  18. Art: The Telling of History through Technology.

    Science.gov (United States)

    Scali, Nancy

    1990-01-01

    Describes several writing projects that use computers to expose students to art, cultural history, and present day technology. Suggests activities for Prehistoric art, Egyptian art, African art, Japanese art, and Native American art. (MG)

  19. Eliciting Audience's Experience to Improve Interactive Art Installation

    DEFF Research Database (Denmark)

    Baharin, Hanif; Morrison, Ann

    2006-01-01

    Designing with the users in mind is one of the widely accepted design practices in the Interaction Design field. On the other hand, it can be said that audience's experience is the heart of an interactive art. Since Interaction Design has shown that user's involvement in the design process can...... be beneficial, it is speculated that involving the audiences in the creative process of developing an interactive art piece can make the artist improve the art in general and the audience's experience in particular. In this paper, the experience of eliciting the experience of the audiences of an interactive art...

  20. New Technologies, New Possibilities for the Arts and Multimodality in English Language Arts

    Science.gov (United States)

    Williams, Wendy R.

    2014-01-01

    This article discusses the arts, multimodality, and new technologies in English language arts. It then turns to the example of the illuminated text--a multimodal book report consisting of animated text, music, and images--to consider how art, multimodality, and technology can work together to support students' reading of literature and inspire…

  1. For a complete preservation of the new media art: Notes on art technology

    Directory of Open Access Journals (Sweden)

    Pablo Gobira

    2016-09-01

    Full Text Available This work discuss on digital art and its preservation. Being a kind of art recognized as born digital, it is among the field of contemporary art and the wide field of digital technology. At the same time, it is part of a society in which the technology has established itself worldwide providing means to criticize the idea of "digital" as advancement or progress. Based on those assumptions, we have tried to think about the complexity of that artistic expression which is manifested in its preservation. In this article, which features notes derived from research on art and its preservation, we seek to think on the relationship between art and data and how the preservation effort beyond the data (informational/computational of technological art work reveals its statute from its industrial and artistic composition.

  2. Proteinaceous molecules mediating Bifidobacterium-host interactions

    Directory of Open Access Journals (Sweden)

    Lorena Ruiz

    2016-08-01

    Full Text Available Bifidobacteria are commensal microoganisms found in the gastrointestinal tract.Several strains have been attributed beneficial traits at local and systemic levels, through pathogen exclusion or immune modulation, among other benefits. This has promoted a growing industrial and scientific interest in bifidobacteria as probiotic supplements. However, the molecular mechanisms mediating this cross-talk with the human host remain unknown. High-throughput technologies, from functional genomics to transcriptomics, proteomics and interactomics coupled to the development of both in vitro and in vivo models to study the dynamics of the intestinal microbiota and their effects on host cells, have eased the identification of key molecules in these interactions. Numerous secreted or surface-associated proteins or peptides have been identified as potential mediators of bifidobacteria-host interactions and molecular cross-talk, directly participating in sensing environmental factors, promoting intestinal colonization or mediating a dialogue with mucosa-associated immune cells. On the other hand, bifidobacteria induce the production of proteins in the intestine, by epithelial or immune cells, and other gut bacteria, which are key elements in orchestrating interactions among bifidobacteria, gut microbiota and host cells. This review aims to give a comprehensive overview on proteinaceous molecules described and characterized to date, as mediators of the dynamic interplay between bifidobacteria and the human host, providing a framework to identify knowledge gaps and future research needs.

  3. Traditional Culture into Interactive Arts: The Cases of Lion Dance in Temple Lecture

    Science.gov (United States)

    Lee, Wen-Hui; Chen, Chih-Tung; He, Ming-Yu; Hsu, Tao-I.

    The lion dance in Chinese culture is one of profound arts. This work aims to bridge traditional culture and modern multimedia technology and application of network cameras for the interactive tool to design a set of activities to promote the lion as the main body. There consists of the imaging systems and interactive multimedia applications.

  4. Art and technology: assessing their symbiotic relevance to aesthetic ...

    African Journals Online (AJOL)

    One can argue that art and technology are mutually exclusive, meaning that both complement each other, contrary to the general belief that there is nothing like technology in art or vice versa. Some believe that art is just about aesthetics and little utilitarian importance. Thus, since technology could be defined as a ...

  5. The Buddha in the Digital Computer: Art and Technology in Zen and the Art of Motorcycle Maintenance.

    Science.gov (United States)

    Williams, Edwin W.

    The novel, "Zen and the Art of Motorcycle Maintenance" attempts to reconcile the dichotomy that exists between art and technology. The main character, Pirsig, believes that technology, or the making of things, is essentially art for two reasons: the Greeks never separated art from manufacture and real technology does not exploit nature.…

  6. Science, Technology and Arts Research Journal: Site Map

    African Journals Online (AJOL)

    Science, Technology and Arts Research Journal: Site Map. Journal Home > About the Journal > Science, Technology and Arts Research Journal: Site Map. Log in or Register to get access to full text downloads.

  7. Science, Technology and Arts Research Journal: Journal Sponsorship

    African Journals Online (AJOL)

    Science, Technology and Arts Research Journal: Journal Sponsorship. Journal Home > About the Journal > Science, Technology and Arts Research Journal: Journal Sponsorship. Log in or Register to get access to full text downloads.

  8. Mood Swings: An Affective Interactive Art System

    Science.gov (United States)

    Bialoskorski, Leticia S. S.; Westerink, Joyce H. D. M.; van den Broek, Egon L.

    The progress in the field of affective computing enables the realization of affective consumer products, affective games, and affective art. This paper describes the affective interactive art system Mood Swings, which interprets and visualizes affect expressed by a person. Mood Swings is founded on the integration of a framework for affective movements and a color model. This enables Mood Swings to recognize affective movement characteristics as expressed by a person and display a color that matches the expressed emotion. With that, a unique interactive system is introduced, which can be considered as art, a game, or a combination of both.

  9. Audio Interaction in Computer Mediated Games

    Directory of Open Access Journals (Sweden)

    J. R. Parker

    2008-01-01

    Full Text Available The use of sound in an interactive media environment has not been advanced, as a technology, as far as graphics or artificial intelligence. This discussion will explore the use of sound as a way to influence the player of a computer game, will show ways that a game can use sound as input, and will describe ways that the player can influence sound in a game. The role of sound in computer games will be explored some practical design ideas that can be used to improve the current state of the art will be given.

  10. ART AND TECHNOLOGY: ASSESSING THEIR SYMBIOTIC ...

    African Journals Online (AJOL)

    Uche

    influence of technology is the industrial designs or applied arts. Ekong and Ekong ... draw and photoshop said that with technology, production in graphics design and printing now comes with ..... traps and guns were manufactured. So why do ...

  11. Sensemaking in Technology-Use Mediation

    DEFF Research Database (Denmark)

    Bansler, Jørgen P.; Havn, Erling C.

    2006-01-01

    of advanced CSCW technologies is basically a problem of sensemaking. We analyze how a group of “technology-use mediators” (Orlikowski et al. Org. Sci. (1995) 6(4), 423) in a large, multinational company adapted a groupware technology (a “virtual workspace”) to the local organizational context (and vice versa......) by modifying features of the technology, providing ongoing support for users, and promoting appropriate conventions of use. Our findings corroborate earlier research on technology-use mediation, which suggests that such mediators can exert considerable influence on how a particular technology...... will be established and used in an organization. However, we also find that the process of technology-use mediation is much more complex and indeterminate than prior research suggests. The reason being, we argue, that new, advanced CSCW technologies, such as “virtual workspaces” and other groupware applications...

  12. Come, See and Experience Affective Interactive Art

    NARCIS (Netherlands)

    Nijholt, Antinus; Bialoskorski, Leticia S.S.; Westerink, Joyce H.D.M.; Reidsma, Dennis; van den Broek, Egon; Hondorp, G.H.W.

    2009-01-01

    The progress in the field of affective computing enables the realization of affective consumer products, affective games, and affective art. This paper describes the affective interactive art system Mood Swings, which interprets and visualizes affect expressed by a person. Mood Swings is founded on

  13. Depressive symptoms, lifestyle structure, and ART adherence among HIV-infected individuals: a longitudinal mediation analysis.

    Science.gov (United States)

    Magidson, Jessica F; Blashill, Aaron J; Safren, Steven A; Wagner, Glenn J

    2015-01-01

    Despite the well-documented relationship between depression and antiretroviral therapy (ART) nonadherence, few studies have identified explanatory pathways through which depression affects adherence. The current study tested lifestyle structure-the degree of organization and routinization of daily activities-as a mediator of this relationship, given previous evidence of lifestyle structure being associated with both depression and ART nonadherence. HIV-infected individuals starting or re-starting ART in the California Collaborative Treatment Group 578 study (n = 199) were assessed over 48 weeks. Adherence was measured using electronic monitoring caps to determine dose timing and doses taken, and viral load was assessed. The mediating role of lifestyle structure was tested using generalized linear mixed-effects modeling and bootstrapping. Lifestyle significantly mediated the relationship between depression and both measures of ART adherence behavior. Interventions that minimize disruptions to lifestyle structure and link adherence to daily activities may be useful for individuals with depression and ART nonadherence.

  14. Touch, Look and Listen: The Multisensory Experience in Digital Art of Japan

    Directory of Open Access Journals (Sweden)

    Emilia Sosnowska

    2015-11-01

    Full Text Available This paper presents and examines several examples of digital interactive art in Japan. It analyses its roots in traditional East Asian philosophy, which grants the senses a prominent role in perceiving the world. By reflecting on traditional beliefs and contemporary art and technology in Japan, the essay reflects on the expansion of this culturally and traditionally inspired spirituality from its original context in the socio-cultural interpretation of the natural world to contemporary digitally mediated environments. The goal of this paper is to make explicit some of the main traditionally transmitted characteristics and historically conditioned approaches to technology and its use, focusing on multisensory experience. The treatment presents several multimodal artworks by Japanese artists, such as Ryota Kuwakubo, Masaki Fujihata and Kumiko Kushiyama.

  15. COMMUNICATION AND INTERACTION IN ART CLASSES

    Directory of Open Access Journals (Sweden)

    Maja Hrvanović

    2014-04-01

    Full Text Available Numerous indicators affect communication and interaction in art classes. For every teacher, as pedagogue, his successful educational activity is very important as some indicators influence the two-way exchange of information in art classes. Teaching art is very specific way of teaching process, because it is mostly based on exchange of visual information of artistic type which represents a special form of communication. The specificity of artistic information, way of acting on the viewer and intense emotional charge in the process of communication should be used as visual stimulus. The richness of imagery, stimulation of reality, abstraction and other cognitive processes in art classes experientially and visually improve students’ awareness and should be represented and diversified by origin and multiplied by quantity. The research paper aims to demonstrate the importance of connectivity between judgment of taste and ability to evaluate the quality of the work of art in art and non-art schools. Teaching and education in art classes is being realized precisely inside communicative relations and appropriate socio-emotional climate. In this research, visual communication in art classes is defined over the structure of the inventory that will examine the differences between abilities to evaluate the quality of artistic information and the judgment of taste.

  16. Dialectic Antidotes to Critics of the Technology Acceptance Model: Conceptual, Methodological, and Replication Treatments for Behavioural Modelling in Technology-Mediated Environments

    Directory of Open Access Journals (Sweden)

    Weng Marc Lim

    2018-01-01

    Full Text Available The technology acceptance model (TAM is a prominent and parsimonious conceptual lens that is often applied for behavioural modelling in technology-mediated environments. However, TAM has received a great deal of criticism in recent years. This article aims to address some of the most pertinent issues confronting TAM through a rejoinder that offers dialectic antidotes—in the form of conceptual, methodological, and replication treatments—to support the continued use of TAM to understand the peculiarities of user interactions with technology in technology-mediated environments. In doing so, this article offers a useful response to a common but often inadequately answered question about how TAM can continue to be relevant for behavioural modelling in contemporary technology-mediated environments.

  17. The role of medialabs in Ecuadorian public arts Higher Education: first experiences in art, science and technology

    Directory of Open Access Journals (Sweden)

    José M. Ruiz Martín

    2016-06-01

    Full Text Available Public university art education in Ecuador lacks subjects to study the current convergent space between art, science and technology and their creative practices. This situation reveals a certain stagnation under traditional techniques and profiles. The new medialabs of the Faculty of Arts (University of Cuenca and Central University from Ecuador (Quito are implementing the first practices in this regard, repairing the  curriculum deficiencies of these career paths in digital culture and new media art. This study analyzes the characteristics of these centers and the methodology followed to introduce the art and new technologies pioneered in the country.

  18. Robotic Technologies for the Future Force - The ART STO

    National Research Council Canada - National Science Library

    Jaster, Jeffrey F

    2005-01-01

    .... The US Army's ARV Robotic Technologies (ART) Science and Technology Objective (STO) will develop a surrogate platform that will be used as a technology demonstrator for such robotic technologies...

  19. Observations on human-technology interaction aspects in remote handling for fusion

    International Nuclear Information System (INIS)

    Salminen, Karoliina

    2009-01-01

    Remote handling can been seen as cooperation between human and machine. One of the characteristics of remote handling is that there is always a human involved in the technique: there is always a human guiding and supervising the movements and deciding the actions of the machine. Unlike many other fields of remote handling for fusion, the human-technology interaction side has not been studied carefully recently. The state-of-the-art research about different kinds of remote handling systems shows that there is a lot of information available in this subject, but there is a clear need for studies where the special needs of ITER are taken into account. During the PREFIT programme, the human-interaction aspects of remote handling have been studied, and the goal has been to find solutions compatible with ITER. Some of the aspects that make ITER a unique system are its new technology combining state-of-the-art knowledge from several different fields, and its very international working environment. When discussing the human aspects, the fact of the multinational cooperation cannot be neglected. Since the majority of the information found in the literature review is not about remote handling, references need to be taken from other industries, like aviation. This article consists of ITER remote handling relevant findings in state-of-the-art research and information and knowledge gained during the PREFIT programme, especially during the training periods at JET in Culham and at CEA in Fontenay-aux-Roses. It also discusses the importance of human-technology interaction field in remote handling, especially in ITER.

  20. Converging technologies in higher education: paradigm for the "new" liberal arts?

    Science.gov (United States)

    Balmer, Robert T

    2006-12-01

    This article discusses the historic relationship between the practical arts (technology) and the mental (liberal) arts, suggesting that Converging Technologies is a new higher education paradigm that integrates the arts, humanities, and sciences with modern technology. It explains that the paradigm really includes all fields in higher education from philosophy to art to music to modern languages and beyond. To implement a transformation of this magnitude, it is necessary to understand the psychology of change in academia. Union College in Schenectady, New York, implemented a Converging Technologies Educational Paradigm in five steps: (1) create a compelling vision, (2) communicate the vision, (3) empower the faculty, (4) create short-term successes, and (5) institutionalize the results. This case study of Union College demonstrates it is possible to build a pillar of educational excellence based on Converging Technologies.

  1. Histone modifications influence mediator interactions with chromatin

    Science.gov (United States)

    Zhu, Xuefeng; Zhang, Yongqiang; Bjornsdottir, Gudrun; Liu, Zhongle; Quan, Amy; Costanzo, Michael; Dávila López, Marcela; Westholm, Jakub Orzechowski; Ronne, Hans; Boone, Charles; Gustafsson, Claes M.; Myers, Lawrence C.

    2011-01-01

    The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. Genome wide localization studies have demonstrated that Mediator occupancy not only correlates with high levels of transcription, but that the complex also is present at transcriptionally silenced locations. We provide evidence that Mediator localization is guided by an interaction with histone tails, and that this interaction is regulated by their post-translational modifications. A quantitative, high-density genetic interaction map revealed links between Mediator components and factors affecting chromatin structure, especially histone deacetylases. Peptide binding assays demonstrated that pure wild-type Mediator forms stable complexes with the tails of Histone H3 and H4. These binding assays also showed Mediator—histone H4 peptide interactions are specifically inhibited by acetylation of the histone H4 lysine 16, a residue critical in transcriptional silencing. Finally, these findings were validated by tiling array analysis that revealed a broad correlation between Mediator and nucleosome occupancy in vivo, but a negative correlation between Mediator and nucleosomes acetylated at histone H4 lysine 16. Our studies show that chromatin structure and the acetylation state of histones are intimately connected to Mediator localization. PMID:21742760

  2. LEGAL CULTURES AND MEDIATION. INTERACTIONS AND EVOLUTIONS

    Directory of Open Access Journals (Sweden)

    Claudiu Ramon D. BUTCULESCU

    2014-05-01

    Full Text Available Mediation, as an alternative dispute resolution method, is closely connected with the system of legal cultures. Mediation is an important link between legal culture and the judicial system. Mediation also acts as an interface between internal legal culture and external legal culture. This paper addresses the issues regarding the links and interactions between mediation and legal cultures, as well as the effects that arise from these interactions.

  3. Swift Guanxi in online marketplace : The role of computer-mediated-communication technologies

    NARCIS (Netherlands)

    Ou, C.X.J.; Pavlou, P.A.; Davison, R.M.

    2014-01-01

    The concept of guanxi (i.e., a close and pervasive interpersonal relationship) has received little attention in the literature on online marketplaces, perhaps due to their impersonal nature. However, we propose that computer-mediated communication (CMC) technologies can mimic traditional interactive

  4. Science, Technology and Arts Research Journal

    African Journals Online (AJOL)

    Science, Technology and Arts Research Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 1, No 1 (2012) >. Log in or Register to get access to full text downloads.

  5. Science, Technology and Arts Research Journal

    African Journals Online (AJOL)

    Science, Technology and Arts Research Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 1, No 2 (2012) >. Log in or Register to get access to full text downloads.

  6. Industrial Arts Test Development, Book III. Resource Items for Graphics Technology, Power Technology, Production Technology.

    Science.gov (United States)

    New York State Education Dept., Albany.

    This booklet is designed to assist teachers in developing examinations for classroom use. It is a collection of 955 objective test questions, mostly multiple choice, for industrial arts students in the three areas of graphics technology, power technology, and production technology. Scoring keys are provided. There are no copyright restrictions,…

  7. Digital technologies and their impact on Higher Education. The new mediations

    Directory of Open Access Journals (Sweden)

    Juan de Pablos Pons

    2018-03-01

    Full Text Available This work proposes a reflection on the evolution of media in the digital age, requires us to advance in knowledge about mediation and remediation processes, favored by technologies, differentiating them from those generated so far by traditional analogue media (printed book, film, television. Digitization has given rise to new realities and proposals, such as video games, social networks or augmented reality applications. The next step in our media culture is the multiplication and continuous diversification of formats, but also new forms of mediated interaction. The mediation processes generated contribute to the modification of communication models and teaching methods. And this has an impact on educational institutions, and also on higher education. As a contribution to its analysis, the concept of technological remediation is provided and defined. The new information and communication technologies (ICT represent, under the considerations formulated here, an opportunity for change some forms and procedures of main areas of the higher education: teaching, research and management. Being proactive in this new reality is relevant, since the adaptation effort is linked to the survival of the university itself.

  8. Navigating the Arts in an Electronic Sea.

    Science.gov (United States)

    Brouch, Virginia

    1994-01-01

    The 1990s will usher in increasingly sophisticated interactive multimedia technologies leading to widespread employment of virtual reality. The arts (visual, music, drama, dance, and creative writing) are intimately involved with instructional technology's future. The arts provide both adult (commercial) creators and contributors to the programs…

  9. Mood swings: design and evaluation of affective interactive art

    NARCIS (Netherlands)

    Bialoskorski, Leticia S.S.; Westerink, Joyce H.D.M.; van den Broek, Egon

    2009-01-01

    The field of affective computing is concerned with developing emphatic products, such as affective consumer products, affective games, and affective art. This paper describes Mood Swings, an affective interactive art system, which interprets and visualizes affect expressed by a person. Mood Swings

  10. PulsArt

    DEFF Research Database (Denmark)

    Fritsch, Jonas; Fogtmann, Maiken Hillerup; Sommer, Henrik

    2005-01-01

    Recent years have seen a growing interest in considering the domestic household as a new and important domain for interaction design. In this paper we present pulsArt - a physical and digital installation designed for the home to represent different family members’ level of activity by water...... running down blocks of salt based on a real-time reading of the individual family member’s pulse. We describe how pulsArt explores novel ways of looking at the interaction between the physical, the social and the technological and how it acts as a context-aware artefact, amplifying the domestic setting...

  11. INTERACTIONS MEDIATED BY TECHNOLOGY IN THE CLASSROOM: THE USE OF SOCIAL NETWORKS AND THE DIGITAL DIVIDE

    Directory of Open Access Journals (Sweden)

    Ranice Hoehr Pedrazzi Pozzer

    2017-10-01

    Full Text Available The National Program for Access to Secondary Education and Employment (Pronatec, created by the federal government has offered, in recent years, training in technical courses at post-secondary level for young people and adults inserted in the educational system and who were attending or finishing high school, including the Youth and Adult Education system (EJA. Thus, some classes of technical courses presented a varied profile of students from teenagers who attend public schools and even older adults who are returning to school after years of absence from the education system. The present study analyzed four groups of students aged between 15 and 63 years. This age difference, how the oldest students use or not technology and the kind of relationship between the students in the classroom raised questions about their relationship on social networks. This network usage by the students significantly influenced the pedagogical practice during the course, considering that the students asked the teacher to use it as a teaching and learning resource. The students transit from reality to virtual world with the naturalness of people who were born inserted in this context of interactions mediated by technology.

  12. Virtual art revisited

    Science.gov (United States)

    Ruzanka, S.

    2014-02-01

    Virtual reality art at the turn of the millenium saw an explosion of creative exploration around this nascent technoloy. Though VR art has much in common with media art in general, the affordances of the technology gave rise to unique experiences, discourses, and artistic investigations. Women artists were at the forefront of the medium, shaping its aesthetic and technical development, and VR fostered a range of artistic concerns and experimentation that was largely distinct from closely related forms such as digital games. Today, a new wave of consumer technologies including 3D TV's, gestural and motion tracking interfaces, and headmount displays as viable, low-cost gaming peripherals drives a resurgence in interest in VR for interactive art and entertainment. Designers, game developers, and artists working with these technologies are in many cases discovering them anew. This paper explores ways of reconnecting this current moment in VR with its past. Can the artistic investigations begun in previous waves of VR be continued? How do the similarities and differences in contexts, communities, technologies, and discourses affect the development of the medium?

  13. Application of digital pattern-less molding technology to produce art casting

    Directory of Open Access Journals (Sweden)

    Chen Li1

    2014-11-01

    Full Text Available Compared with the conventional casting process, digital pattern-less casting technology has many advantages such as good machining accuracy, a short processing cycle, and low production cost. It is a new rapid manufacturing technology for castings, integrated with CAD/CAM, casting, CNC machining and many other advanced technologies. With this digital casting technology, no pattern is needed for making molds; it is precise, flexible, and green. Usually, art castings have complex structures and are made in small batches or even made in a single-piece, especially for large-sized art castings. So it has the shortcomings of high cost, low efficiency and long time for making a pattern to produce art castings with the conventional casting processes. However, the digital pattern-less casting technology can be applied to fabricate art castings, since it can greatly shorten the manufacturing cycle and lower the production cost, thus having a very good prospect. In this study, based on the digital pattern-less casting technology, a plaque casting with artistic Chinese characters (a Chinese poem was designed and manufactured, and the production process was demonstrated in detail.

  14. Abstraction and art.

    Science.gov (United States)

    Gortais, Bernard

    2003-07-29

    In a given social context, artistic creation comprises a set of processes, which relate to the activity of the artist and the activity of the spectator. Through these processes we see and understand that the world is vaster than it is said to be. Artistic processes are mediated experiences that open up the world. A successful work of art expresses a reality beyond actual reality: it suggests an unknown world using the means and the signs of the known world. Artistic practices incorporate the means of creation developed by science and technology and change forms as they change. Artists and the public follow different processes of abstraction at different levels, in the definition of the means of creation, of representation and of perception of a work of art. This paper examines how the processes of abstraction are used within the framework of the visual arts and abstract painting, which appeared during a period of growing importance for the processes of abstraction in science and technology, at the beginning of the twentieth century. The development of digital platforms and new man-machine interfaces allow multimedia creations. This is performed under the constraint of phases of multidisciplinary conceptualization using generic representation languages, which tend to abolish traditional frontiers between the arts: visual arts, drama, dance and music.

  15. Creativity, Technology, Art, and Pedagogical Practices

    Science.gov (United States)

    Tillander, Michelle

    2011-01-01

    Creativity serves an important role in culture, education, and the workforce as it "provides the impetus for any act, idea, or product that changes an existing domain or discipline into a new entity." In the 21st century, information technology is forming a powerful alliance with creative practices in the arts and design to establish new domains…

  16. Forms of Mediation: The Case of Interpreter-Mediated Interactions in Medical Systems

    Science.gov (United States)

    Baraldi, Claudio

    2009-01-01

    This paper analyses the forms of mediation in interlinguistic interactions performed in Italian healthcare services and in contexts of migration. The literature encourages dialogic transformative mediation, empowering participants' voices and changing cultural presuppositions in social systems. It may be doubtful, however, whether mediation can…

  17. Boxes with Fires: Wisely Integrating Learning Technologies into the Art Classroom

    Science.gov (United States)

    Gregory, Diane C.

    2009-01-01

    By integrating and infusing computer learning technologies wisely into student-centered or social constructivist art learning environments, art educators can improve student learning and at the same time provide a creative, substantive model for how schools can and should be reformed. By doing this, art educators have an opportunity to demonstrate…

  18. An Interactive Approach to Learning and Teaching in Visual Arts Education

    Science.gov (United States)

    Tomljenovic, Zlata

    2015-01-01

    The present research focuses on modernising the approach to learning and teaching the visual arts in teaching practice, as well as examining the performance of an interactive approach to learning and teaching in visual arts classes with the use of a combination of general and specific (visual arts) teaching methods. The study uses quantitative…

  19. An Interactive Approach to Learning and Teaching in Visual Arts Education

    Directory of Open Access Journals (Sweden)

    Zlata Tomljenović

    2015-09-01

    Full Text Available The present research focuses on modernising the approach to learning and teaching the visual arts in teaching practice, as well as examining the performance of an interactive approach to learning and teaching in visual arts classes with the use of a combination of general and specific (visual arts teaching methods. The study uses quantitative analysis of data on the basis of results obtained from a pedagogical experiment. The subjects of the research were 285 second- and fourth-grade students from four primary schools in the city of Rijeka, Croatia. Paintings made by the students in the initial and final stage of the pedagogical experiment were evaluated. The research results confirmed the hypotheses about the positive effect of interactive approaches to learning and teaching on the following variables: (1 knowledge and understanding of visual arts terms, (2 abilities and skills in the use of art materials and techniques within the framework of planned painting tasks, and (3 creativity in solving visual arts problems. The research results can help shape an optimised model for the planning and performance of visual arts education, and provide guidelines for planning professional development and the further professional education of teachers, with the aim of establishing more efficient learning and teaching of the visual arts in primary school.

  20. Performing Beauty in Participatory Art and Culture

    DEFF Research Database (Denmark)

    Heinrich, Falk

    This book investigates the notion of beauty in participatory art, an interdisciplinary form that necessitates the audience’s agential participation and that is often seen in interactive art and technology-driven media installations. After considering established theories of beauty, for example...

  1. Towards a Phenomenology of Technologically Mediated Moral Change: Or, What Could Mark Zuckerberg Learn from Caregivers in the Southern Netherlands?

    Science.gov (United States)

    Sharon, Tamar

    2017-01-01

    Kamphof offers an illuminating depiction of the technological mediation of morality. Her case serves as the basis for a plea for modesty up and against the somewhat heroic conceptualizations of techno-moral change to date-less logos, less autos, more practice, more relationality. Rather than a displacement of these conceptualizations, I question whether Kamphof's art of living offers only a different perspective: in scale (as a micro-event of techno-moral change), and in unit of analysis (as an art of living oriented to relations with others rather than the relation to the self). As a supplement and not an alternative, this modest art has nonetheless audacious implications for the ethics of surveillance.

  2. Keeping up with Our Students: The Evolution of Technology and Standards in Art Education

    Science.gov (United States)

    Patton, Ryan M.; Buffington, Melanie L.

    2016-01-01

    This article addresses the standards of technology in the visual arts, arguing the standards function as de facto policy, the guidelines that shape what teachers teach. In this study, we investigate how art education standards approach technology as a teaching tool and artmaking medium, analyzing the current National Visual Arts Standards, the…

  3. School of Culinary Arts & Food Technology - Summer Newsletter 2017

    OpenAIRE

    Murphy, James Peter

    2017-01-01

    The School of Culinary Arts and Food Technology, Summer Newsletter captured rfgw many events, research, awards, significant contributions ans special civic and community activities which the students and staff members of the school have successfully completed leading up to the summer period of 2017. These activities could not be completed without the on-going and active support of the schools 'INSPIRED' friends of Culinary Arts (sponsors).

  4. Sensors and Technologies in Spain: State-of-the-Art

    Directory of Open Access Journals (Sweden)

    Gonzalo Pajares

    2014-08-01

    Full Text Available The aim of this special issue was to provide a comprehensive view on the state-of-the-art sensor technology in Spain. Different problems cause the appearance and development of new sensor technologies and vice versa, the emergence of new sensors facilitates the solution of existing real problems. [...

  5. Volatile-mediated interactions in the rhizosphere

    NARCIS (Netherlands)

    Cordovez da Cunha, Viviane

    2016-01-01

    Plants and microorganisms are constantly engaged in highly dynamic interactions both above- and belowground. Several of these interactions are mediated by volatile organic compounds (VOCs), small carbon-based compounds with high vapor pressure at ambient temperature. In the rhizosphere, VOCs have

  6. Plastic Technology (Production). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

    Science.gov (United States)

    Claus, Robert; And Others

    This course guide for a plastic technology course is one of four developed for the production area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--energy/power and graphic communications.) Part 1 provides such introductory information as a definition and…

  7. Contemporary Urban Media Art – Images of Urgency

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    . Under the themes ‘intensity’, ‘intelligence’ and ‘immersion’ the dissertation examines some of the ways in which our experience is affected by ubiquitous technological mediation, especially in hi-tech urban contexts, and simultaneously how artistic interventions work towards a critical understanding......The dissertation examinesfrom a combined academic and curatorial perspective how urban media art – media aesthetic art forms situated in the urban context – may be considered contemporary in the understanding of art that departs from, responds to and co-exists with ‘time’ and temporal experience...... and exploitation of this new condition in our technological reality. I suggest that urban media art – as sensible constructions of temporal emergency images situated in the urban environment – potentially interfere with the temporal experiences we are offered in our communicative context. Based on this, we can...

  8. Arts and technology - Mosaic new techniques and procedures

    Science.gov (United States)

    Papiu, G. A.; Suciu, N.

    2017-05-01

    The relationship between art and technique has been along the time one that is inseparable and systematic, artists appealing to various technologies, tools and practices that help them stimulate their imagination. Today there is a new category of artists, coming from a technical or scientific field, that are being 'trapped’ in this ‘game of art”. The mosaic, even if it is an old technique, responded to the social requirements and it evolved over time, being constantly related to aesthetic and artistic thinking, discoveries of science, assimilating permanent new techniques and technologies, diversifying its artistic forms of expression and methods of transposition. Not being bound any more to a religious institution, which was its birth place, today, she migrated to all public spaces. Works of art in public space have become today an active factor in reshaping the urban aesthetic landscape.

  9. School of Culinary Arts & Food Technology - Spring Newsletter 2017

    OpenAIRE

    Murphy, James Peter

    2017-01-01

    The School of Culinary Arts and Food Technology, Spring Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed leading up to the Spring period of 2017. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' friends of Culinary Arts (sponsors).

  10. School of Culinary Arts & Food Technology - Summer Newsletter 2018

    OpenAIRE

    Murphy, James Peter

    2018-01-01

    The School of Culinary Arts and Food Technology, Summer Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed up to the Summer period of 2018. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' friends of Culinary Arts (school sponsors).

  11. School of Culinary Arts & Food Technology - Winter Newsletter 2017

    OpenAIRE

    Murphy, James Peter

    2017-01-01

    The School of Culinary Arts and Food Technology, Winter Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed leading up to the Winter period of 2017. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' Friends of Culinary Arts (sponsors).

  12. Effects of Depression Alleviation on ART Adherence and HIV Clinic Attendance in Uganda, and the Mediating Roles of Self-Efficacy and Motivation.

    Science.gov (United States)

    Wagner, Glenn J; Ghosh-Dastidar, Bonnie; Robinson, Eric; Ngo, Victoria K; Glick, Peter; Mukasa, Barbara; Musisi, Seggane; Akena, Dickens

    2017-06-01

    With depression known to impede HIV care adherence and retention, we examined whether depression alleviation improves these disease management behaviors. A sample of 1028 depressed HIV clients in Uganda enrolled in a cluster randomized controlled trial of two depression care models, and were surveyed over 12 months. Serial regression analyses examined whether depression alleviation was associated with self-reported antiretroviral therapy (ART) adherence and clinic attendance at month 12, and whether these relationships were mediated by self-efficacy and motivation. Among those with major depression, depression alleviation was associated with better ART adherence and clinic attendance at month 12; these relationships were fully mediated by self-efficacy at month 12, while adherence motivation partially mediated the relationship between depression alleviation and ART adherence. When both mediators were entered simultaneously, only self-efficacy was a significant predictor and still fully mediated the relationship between depression alleviation and adherence. These findings suggest that depression alleviation benefits both ART adherence and clinic attendance, in large part through improved confidence and motivation to engage in these disease management behaviors.

  13. Culture's Impact on Technology Mediated Learning: The Role of Horizontal and Vertical Individualism and Collectivism

    OpenAIRE

    Steven Hornik; Anna Tupchiy

    2006-01-01

    The horizontal and vertical dimensions of individualism and collectivism are an important characteristic of cultures. These dimensions have many implications for the ways in which individual learners use and respond to interactive technologies. This article reports on a study that investigated the impact of culture, specifically horizontal individualism (HI), vertical individualism (VI), horizontal collectivism (HC), and vertical collectivism (VC) on the effectiveness of technology mediated l...

  14. Augmented reality art from an emerging technology to a novel creative medium

    CERN Document Server

    Geroimenko, Vladimir

    2014-01-01

    This is the first ever book on augmented reality art. It is written by a team of world-leading artists, researchers and practitioners, pioneering in the use of augmented reality technology as a novel artistic medium. The book explores a wide range of major aspects of augmented reality art and its enabling technology. It is intended to be a starting point and essential reading not only for artists, researchers and technology developers, but also for students (both graduates and undergraduates) and everyone who is interested in emerging augmented reality technology and its current and future app

  15. Strain mediated interaction of adatom dimers

    OpenAIRE

    Kappus, Wolfgang

    2013-01-01

    An earlier model for substrate strain mediated interactions between monomer adatoms is extended to the interaction of monomers with dimers and the interaction of dimers. While monomers (sitting on high symmetric sites) are supposed to create isotropic stress on the substrate, dimers would create anisotropic stress caused by stretching their bond. Resulting interactions are strongly angle dependent and also reflect the elastic anisotropy of the substrate. The applicability of a continuum elast...

  16. Sustainability of University Technology Transfer: Mediating Effect of Inventor’s Technology Service

    Directory of Open Access Journals (Sweden)

    Fang Li

    2018-06-01

    Full Text Available Based on the perspective of knowledge transfer and the technology acceptance model (TAM, this paper constructs a university technology transfer sustainable development model that considers the inventor’s technology service from the perspective of the long-term cooperation of enterprise, and analyzes the mediating effect of the inventor’s technology service on university technology transfer sustainability. By using 270 questionnaires as survey data, it is found that the availability of an inventor’s technology service has a significant positive impact on the attitude tendency and practice tendency of enterprise long-term technological cooperation; enterprise technology absorption capacity and trust between a university and an enterprise also have significant influence on an inventor’s technical service availability. Therefore, the inventor’s technology service acts as a mediator in the relationship between university technology transfer sustainability and influence factors. Universities ought to establish the technology transfer model, which focuses on the inventor’s tacit knowledge transfer service, and promotes the sustainable development of the university.

  17. [The analysis of the bipolarity features in students of arts and the students of technology].

    Science.gov (United States)

    Siwek, Marcin; Dudek, Dominika; Arciszewska, Aleksandra; Filar, Dorota; Rybicka, Monika; Cieciora, Anna; Pilecki, Maciej Wojciech

    2013-01-01

    The aim of the research was to assess the prevalence of the bipolar spectrum features among students of a variety of faculties, by dividing them arbitrarily into 'art' or 'technology' cohorts. 120 subjects were examined, including 57 students of arts, and 63 students of technology. The tools used included a basic socio-demographic questionnaire and the Hirschfeld Mood Disorder Questionnaire (MDQ). The bipolar spectrum features (as identified by the MDQ responses) were significantly more prevalent among the students of arts, as compared to the students of technology (28.2% vs. 4.8%, p students of technology, the students of arts were more likely to: 1) report mood patterns of intermittent 'highs' and 'lows' (49.1% vs. 15.9%, p students of arts indicate a significant association between artistic talents and creativity, and the bipolar spectrum disorders.

  18. ARV robotic technologies (ART): a risk reduction effort for future unmanned systems

    Science.gov (United States)

    Jaster, Jeffrey F.

    2006-05-01

    The Army's ARV (Armed Robotic Vehicle) Robotic Technologies (ART) program is working on the development of various technological thrusts for use in the robotic forces of the future. The ART program will develop, integrate and demonstrate the technology required to advance the maneuver technologies (i.e., perception, mobility, tactical behaviors) and increase the survivability of unmanned platforms for the future force while focusing on reducing the soldiers' burden by providing an increase in vehicle autonomy coinciding with a decrease in the total number user interventions required to control the unmanned assets. This program will advance the state of the art in perception technologies to provide the unmanned platform an increasingly accurate view of the terrain that surrounds it; while developing tactical/mission behavior technologies to provide the Unmanned Ground Vehicle (UGV) the capability to maneuver tactically, in conjunction with the manned systems in an autonomous mode. The ART testbed will be integrated with the advanced technology software and associated hardware developed under this effort, and incorporate appropriate mission modules (e.g. RSTA sensors, MILES, etc.) to support Warfighter experiments and evaluations (virtual and field) in a military significant environment (open/rolling and complex/urban terrain). The outcome of these experiments as well as other lessons learned through out the program life cycle will be used to reduce the current risks that are identified for the future UGV systems that will be developed under the Future Combat Systems (FCS) program, including the early integration of an FCS-like autonomous navigation system onto a tracked skid steer platform.

  19. Service Interaction Flow Analysis Technique for Service Personalization

    DEFF Research Database (Denmark)

    Korhonen, Olli; Kinnula, Marianne; Syrjanen, Anna-Liisa

    2017-01-01

    Service interaction flows are difficult to capture, analyze, outline, and represent for research and design purposes. We examine how variation of personalized service flows in technology-mediated service interaction can be modeled and analyzed to provide information on how service personalization...... could support interaction. We have analyzed service interaction cases in a context of technology-mediated car rental service. With the analysis technique we propose, inspired by Interaction Analysis method, we were able to capture and model the situational service interaction. Our contribution regarding...... technology-mediated service interaction design is twofold: First, with the increased understanding on the role of personalization in managing variation in technology-mediated service interaction, our study contributes to designing service management information systems and human-computer interfaces...

  20. A Review of Multi-Sensory Technologies in a Science, Technology, Engineering, Arts and Mathematics (STEAM) Classroom

    Science.gov (United States)

    Taljaard, Johann

    2016-01-01

    This article reviews the literature on multi-sensory technology and, in particular, looks at answering the question: "What multi-sensory technologies are available to use in a science, technology, engineering, arts and mathematics (STEAM) classroom, and do they affect student engagement and learning outcomes?" Here engagement is defined…

  1. Synchronous Computer-Mediated Communication and Interaction

    Science.gov (United States)

    Ziegler, Nicole

    2016-01-01

    The current study reports on a meta-analysis of the relative effectiveness of interaction in synchronous computer-mediated communication (SCMC) and face-to-face (FTF) contexts. The primary studies included in the analysis were journal articles and dissertations completed between 1990 and 2012 (k = 14). Results demonstrate that interaction in SCMC…

  2. SmartMom Rebooted: A Cyberfeminist Art Collective Reflects on its Earliest Work of Internet Art

    Directory of Open Access Journals (Sweden)

    Faith Wilding

    2016-12-01

    Full Text Available subRosa, a cyberfeminist art and theory collective was organized as a reading group researching issues of feminism, science, embodiment, and technology. As part of a residency at Carnegie Mellon University’s “STUDIO for Creative Inquiry” subRosa members Faith Wilding and Hyla Willis collaborated to produce 'SmartMom' our first interactive Web-based project about the rapidly developing new biotechnological/medical/reproductive field known as Assisted Reproductive Technologies (ART and the increasing medical, technological, and state control of women’s bodies, sexuality, pregnancy, and birth. This illustrated essay describes the project’s origins, theory, research, and visual components, as well as its pedagogical and critical content, which examines the ways in which reproduction is being technologically managed increasingly linked to “smart” space and military technologies.

  3. Spacecraft Environmental Interactions Technology, 1983

    Science.gov (United States)

    1985-01-01

    State of the art of environment interactions dealing with low-Earth-orbit plasmas; high-voltage systems; spacecraft charging; materials effects; and direction of future programs are contained in over 50 papers.

  4. Design and Research on Platform to Enhance College Students’ Art Appreciation Capability Based on Modern Information Technology

    Directory of Open Access Journals (Sweden)

    Shen Xifei

    2015-01-01

    Full Text Available Nowadays, with the rapid development of modern information technology, the college students could not preferably choose and learn to enhance their own art appreciation capability. Therefore, the colleges and universities have a more urgent desire to organize, develop and provide a good platform to enhance the college students’ art appreciation capability based on modern information technology. This paper describes how to enhance the art appreciation capability in detail, and designs and analyzes the platform to enhance college students’ art appreciation capability based on modern information technology---the “Music Corner” and the “Dance Corner”, indicating that the exchange platform built with modern information technology can promotes the college students’ art appreciation capability. Finally, through the analysis of statistical results of the questionnaire, college students are fonder of art appreciation after the establishment of platform, more inclined to the comprehensive learning of art, more brave to express their own sense of art, and fonder of artistic creation.

  5. Merging arts and bioethics: An interdisciplinary experiment in cultural and scientific mediation.

    Science.gov (United States)

    Couture, Vincent; Bélisle-Pipon, Jean-Christophe; Cloutier, Marianne; Barnabé, Catherine

    2017-10-01

    How to engage the public in a reflection on the most pressing ethical issues of our time? What if part of the solution lies in adopting an interdisciplinary and collaborative strategy to shed light on critical issues in bioethics? An example is Art + Bioéthique, an innovative project that brought together bioethicists, art historians and artists with the aim of expressing bioethics through arts in order to convey the "sensitive" aspect of many health ethics issues. The aim of this project was threefold: 1) to identify and characterize mechanisms for the meeting of arts and bioethics; 2) to experiment with and co-construct a dialogue between arts and bioethics; and 3) to initiate a public discussion on bioethical issues through the blending of arts and bioethics. In connection with an exhibition held in March 2016 at the Espace Projet, a non-profit art space in Montréal (Canada), the project developed a platform that combined artworks, essays and cultural & scientific mediation activities related to the work of six duos of young bioethics researchers and emerging artists. Each duo worked on a variety of issues, such as the social inclusion of disabled people, the challenges of practical applications of nanomedicine and regenerative medicine, and a holistic approach to contemporary diseases. This project, which succeeded in stimulating an interdisciplinary dialogue and collaboration between bioethics and arts, is an example of an innovative approach to knowledge transfer that can move bioethics reflection into the public space. © 2017 John Wiley & Sons Ltd.

  6. Thermal expression of intersubjectivity offers new possibilities to human-machine and technologically mediated interactions

    Directory of Open Access Journals (Sweden)

    Arcangelo eMerla

    2014-07-01

    Full Text Available The evaluation of the psychophysiological state of the interlocutor is an important element of interpersonal relationships and communication. Thermal infrared imaging has proved to be a reliable tool for non-invasive and contact-less evaluation of vital signs, psychophysiological responses and emotional states. This technique is quickly spreading in many fields, from psychometrics to social and developmental psychology; and from the touch-less monitoring of vital signs and stress, up to the human-machine interaction. In particular, thermal IR imaging promises to be of use for gathering information about affective states in social situations. This paper presents the state of the art of thermal infrared imaging in psychophysiology and in the assessment of affective states. The goal is to provide insights about its potentialities and limits for its use in human-artificial agent interaction in order to contribute to a major issue in the field: the perception by an artificial agent of human psychophysiological and affective states.

  7. On the Convergence of Affective and Persuasive Technologies in Computer- Mediated Health-Care Systems

    Directory of Open Access Journals (Sweden)

    Rebeca I. García-Betances

    2015-01-01

    Full Text Available This paper offers a portrayal of how affective computing and persuasive technologies can converge into an effective tool for interfacing biomedical engineering with behavioral sciences and medicine. We describe the characteristics, features, applications, present state of the art, perspectives, and trends of both streams of research. In particular, these streams are analyzed in light of the potential contribution of their convergence for improving computer-mediated health-care systems, by facilitating the modification of patients’ attitudes and behaviors, such as engagement and compliance. We propose a framework for future research in this emerging area, highlighting how key constructs and intervening variables should be considered. Some specific implications and challenges posed by the convergence of these two technologies in health care, such as paradigm change, multimodality, patients’ attitude improvement, and cost reduction, are also briefly addressed and discussed.

  8. Art of hydrogen technology: review; Arte da tecnologia do hidrogenio - revisao

    Energy Technology Data Exchange (ETDEWEB)

    Capaz, Rafael Silva; Marvulle, Valdecir [Universidade Federal de Itajuba (UNIFEI), MG (Brazil). Inst. de Recursos Naturais

    2006-07-01

    The era we live in, since many years ago is called 'petroleum age', because still depends on 'black gold'. It is known however that petroleum will be over on day. This could justify the growing research into new energy sources which appear as renewable alternatives and with less environmental impact. The hydrogen technology art, increasingly nowadays, involves production steps since gasification reactions to thermal decomposition, storage in gas, liquid and intermediary compounds state, transportation and still its use especially in fuel cells. (author)

  9. Utilizing media arts principles for developing effective interactive neurorehabilitation systems.

    Science.gov (United States)

    Rikakis, Thanassis

    2011-01-01

    This paper discusses how interactive neurorehabilitation systems can increase their effectiveness through systematic integration of media arts principles and practice. Media arts expertise can foster the development of complex yet intuitive extrinsic feedback displays that match the inherent complexity and intuitive nature of motor learning. Abstract, arts-based feedback displays can be powerful metaphors that provide re-contextualization, engagement and appropriate reward mechanisms for mature adults. Such virtual feedback displays must be seamlessly integrated with physical components to produce mixed reality training environments that promote active, generalizable learning. The proposed approaches are illustrated through examples from mixed reality rehabilitation systems developed by our team.

  10. Weak Molecular Interactions in Clathrin-Mediated Endocytosis

    Directory of Open Access Journals (Sweden)

    Sarah M. Smith

    2017-11-01

    Full Text Available Clathrin-mediated endocytosis is a process by which specific molecules are internalized from the cell periphery for delivery to early endosomes. The key stages in this step-wise process, from the starting point of cargo recognition, to the later stage of assembly of the clathrin coat, are dependent on weak interactions between a large network of proteins. This review discusses the structural and functional data that have improved our knowledge and understanding of the main weak molecular interactions implicated in clathrin-mediated endocytosis, with a particular focus on the two key proteins: AP2 and clathrin.

  11. Mediated Scenarios: The Infusion of Art and Design in Scenario Practices

    DEFF Research Database (Denmark)

    Selin, Cynthia Lea

    2014-01-01

    Applied and theoretical research into novel foresight methods is pushing forward to considerhow art and design are relevant, and perhaps even necessary, for effective interventions. Taking the governance of emerging energy technologies as a focal area, this preliminary research for aMarie Curie...

  12. Arts, Religion and the New Social Order: Emerging Trends in ...

    African Journals Online (AJOL)

    Arts, Religion and the New Social Order: Emerging Trends in Mediation in an Age ... and religion as culturally interactive phenomena may not be strange, but the ... things upon the mastery of applied elements of visual, performing and media ...

  13. Performance Evaluation of the MyT4 Technology for Determining ART Eligibility.

    Science.gov (United States)

    Sitoe, Nádia; Macamo, Rosa; Meggi, Bindiya; Tobaiwa, Ocean; Loquiha, Osvaldo; Bollinger, Timothy; Vojnov, Lara; Jani, Ilesh

    2016-01-01

    In resource-limited countries, CD4 T-cell (CD4) testing continues to be used for determining antiretroviral therapy (ART) initiation eligibility and opportunistic infection monitoring. To support expanded access to CD4 testing, simple and robust technologies are necessary. We conducted this study to evaluate the performance of a new Point-of-Care (POC) CD4 technology, the MyT4, compared to conventional laboratory CD4 testing. EDTA venous blood from 200 HIV-positive patients was tested in the laboratory using the MyT4 and BD FACSCalibur™. The MyT4 had an r2 of 0.82 and a mean bias of 12.3 cells/μl. The MyT4 had total misclassifications of 14.7% and 8.8% when analyzed using ART eligibility thresholds of 350 and 500 cells/μl, respectively. We conclude that the MyT4 performed well in classifying patients using the current ART initiation eligibility thresholds in Mozambique when compared to the conventional CD4 technology.

  14. Sonic mediations: body, sound, technology

    NARCIS (Netherlands)

    Birdsall, C.; Enns, A.

    2008-01-01

    Sonic Mediations: Body, Sound, Technology is a collection of original essays that represents an invaluable contribution to the burgeoning field of sound studies. While sound is often posited as having a bridging function, as a passive in-between, this volume invites readers to rethink the concept of

  15. CALL from an Ecological Perspective: How a Teacher Perceives Affordance and Fosters Learner Agency in a Technology-Mediated Language Classroom

    Science.gov (United States)

    Liu, Qian; Chao, Chin-Chi

    2018-01-01

    The possibility of exploiting technology for more robust and meaningful learning and teaching has invoked messianic responses from the language education community. Yet to be explored are teachers' pedagogical choices based on the perceived technological affordances as well as interactions between teacher and student agency mediated by these…

  16. Technological Mediation and Power: Postphenomenology, Critical Theory, and Autonomist Marxism

    NARCIS (Netherlands)

    Bantwal Rao, M.; Jongerden, J.P.; Lemmens, P.C.; Ruivenkamp, G.T.P.

    2015-01-01

    This article focuses on the power of technological mediation from the point of view of autonomist Marxism (Hardt, Negri, Virno, Berardi, Lazzarrato). The first part of the article discusses the theories developed on technological mediation in postphenomenology (Ihde, Verbeek) and critical theory of

  17. Security training with interactive laser-video-disk technology

    International Nuclear Information System (INIS)

    Wilson, D.

    1988-01-01

    DOE, through its contractor EG and G Energy Measurements, Inc., has developed a state-of-the-art interactive-video system for use at the Department of Energy's Central Training Academy. Called the Security Training and Evaluation Shooting System (STRESS), the computer-driven decision shooting system employs the latest is laservideo-disk technology. STRESS is designed to provide realistic and stressful training for security inspectors employed by the DOE and its contractors. The system uses wide-screen video projection, sophisticated scenario-branching technology, and customized video scenarios especially designed for the DOE. Firing a weapon that has been modified to shoot ''laser bullets,'' and wearing a special vest that detects ''hits'': the security inspector encounters adversaries on the wide screen who can shoot or be shot by the inspector in scenarios that demand fast decisions. Based on those decisions, the computer provides instantaneous branching to different scenes, giving the inspector confrontational training with the realism and variability of real life

  18. State-of-the-art report of spent fuel management technology

    International Nuclear Information System (INIS)

    Ro, S. G.; Park, S. W.; Shin, Y. J. and others

    1998-06-01

    Essential technologies for a long-term management of domestic nuclear fuel have been described in this report. The technologies of interest are advanced processes for spent fuel management, spent fuel examination technology, evaluation of radiation effect on equipment, chemical characterization of spent fuel, and hot cell-related technology state of the art for the above-mentioned technologies has been reviewed and analyzed in detail. As a result, a future R and D direction that seems to be appropriate for us is drawn up in due consideration of in- and out-circumstances encountered with. (author). 304 refs., 28 tabs., 43 figs

  19. From interventions to interactions: Science Museum Arts Projects’ history and the challenges of interpreting art in the Science Museum

    Directory of Open Access Journals (Sweden)

    Hannah Redler

    2009-06-01

    Full Text Available Hannah Redler’s paper examines the 13 year history of Science Museum, London’s contemporary art programme and explores how changing cultural conditions and the changing function of museums are making the questions raised by bringing art into the Science Museum context increasingly significant. It looks at how Science Museum Arts Projects started as a quirky, experimental sideline aimed at shaking up the Museum and its visitors’ assumptions, but has now become a fundamental means by which the Science Museum chooses to represent the impact of science, medicine, engineering and technology on peoples’ everyday lives.

  20. Assisted reproductive technology (ART) treatment in women with schizophrenia or related psychotic disorder

    DEFF Research Database (Denmark)

    Ebdrup, Ninna H; Assens, Maria; Hougaard, Charlotte O

    2014-01-01

    To determine the prevalence rate of women with a diagnosis of schizophrenia or related psychotic disorder in assisted reproductive technology (ART) treatment and to study these women's fertility treatment outcome in comparison to women with no psychotic disorders.......To determine the prevalence rate of women with a diagnosis of schizophrenia or related psychotic disorder in assisted reproductive technology (ART) treatment and to study these women's fertility treatment outcome in comparison to women with no psychotic disorders....

  1. Enhancing Science Literacy and Art History Engagement at Princeton Through Collaboration Between the University Art Museum and the Council on Science and Technology

    Science.gov (United States)

    Riihimaki, C. A.; White, V. M.

    2016-12-01

    The importance of innovative science education for social science and humanities students is often under-appreciated by science departments, because these students typically do not take science courses beyond general education requirements, nor do they contribute to faculty research programs. However, these students are vitally important in society—for example as business leaders or consultants, and especially as voters. In these roles, they will be confronted with decisions related to science in their professional and personal lives. The Council on Science and Technology at Princeton University aims to fill this education gap by developing and supporting innovative programs that bring science to cross-disciplinary audiences. One of our most fruitful collaborations has been with the Princeton University Art Museum, which has an encyclopedic collection of over 92,000 works of art, ranging from antiquity to the contemporary. Our work includes 1) bringing introductory environmental science courses to the Museum to explore how original works of art of different ages can serve as paleo-environmental proxies, thereby providing a means for discussing broader concepts in development of proxies and validation of reconstructions; 2) sponsoring a panel aimed at the general public and composed of science faculty and art historians who discussed the scientific and art historical contexts behind Albert Bierstadt's Mount Adams, Washington, 1875 (oil on canvas, gift of Mrs. Jacob N. Beam, accession number y1940-430), including the landscape's subjects, materials, technique, and style; and 3) collaborating on an installation of photographs relevant to a freshman GIS course, with an essay about the artwork written by the students. This first-hand study of works of art encourages critical thinking and an empathetic approach to different historical periods and cultures, as well as to the environment. Our collaboration additionally provides an opportunity to engage more students in

  2. Pollinator-mediated interactions in experimental arrays vary with neighbor identity.

    Science.gov (United States)

    Ha, Melissa K; Ivey, Christopher T

    2017-02-01

    Local ecological conditions influence the impact of species interactions on evolution and community structure. We investigated whether pollinator-mediated interactions between coflowering plants vary with plant density, coflowering neighbor identity, and flowering season. We conducted a field experiment in which flowering time and floral neighborhood were manipulated in a factorial design. Early- and late-flowering Clarkia unguiculata plants were placed into arrays with C. biloba neighbors, noncongeneric neighbors, additional conspecific plants, or no additional plants as a density control. We compared whole-plant pollen limitation of seed set, pollinator behavior, and pollen deposition among treatments. Interactions mediated by shared pollinators depended on the identity of the neighbor and possibly changed through time, although flowering-season comparisons were compromised by low early-season plant survival. Interactions with conspecific neighbors were likely competitive late in the season. Interactions with C. biloba appeared to involve facilitation or neutral interactions. Interactions with noncongeners were more consistently competitive. The community composition of pollinators varied among treatment combinations. Pollinator-mediated interactions involved competition and likely facilitation, depending on coflowering neighbor. Experimental manipulation helped to reveal context-dependent variation in indirect biotic interactions. © 2017 Botanical Society of America.

  3. Sonic Interactions in Virtual Reality: State of the Art, Current Challenges, and Future Directions.

    Science.gov (United States)

    Serafin, Stefania; Geronazzo, Michele; Erkut, Cumhur; Nilsson, Niels C; Nordahl, Rolf

    2018-03-01

    A high-fidelity but efficient sound simulation is an essential element of any VR experience. Many of the techniques used in virtual acoustics are graphical rendering techniques suitably modified to account for sound generation and propagation. In recent years, several advances in hardware and software technologies have been facilitating the development of immersive interactive sound-rendering experiences. In this article, we present a review of the state of the art of such simulations, with a focus on the different elements that, combined, provide a complete interactive sonic experience. This includes physics-based simulation of sound effects and their propagation in space together with binaural rendering to simulate the position of sound sources. We present how these different elements of the sound design pipeline have been addressed in the literature, trying to find the trade-off between accuracy and plausibility. Recent applications and current challenges are also presented.

  4. Material interaction in art therapy assessment

    NARCIS (Netherlands)

    Pénzes, I.J.N.J.; Hooren, S. van; Dokter, D.; Smeijsters, H.; Hutschemaekers, G.J.M.

    2014-01-01

    Diverse approaches to art therapy assessment agree that art materials should play a central role. However, relatively little research is done on the role of different art materials. This article describes the results of a qualitative study on the use of art materials by art therapists in art therapy

  5. Combining Brain–Computer Interfaces and Assistive Technologies: State-of-the-Art and Challenges

    Science.gov (United States)

    Millán, J. d. R.; Rupp, R.; Müller-Putz, G. R.; Murray-Smith, R.; Giugliemma, C.; Tangermann, M.; Vidaurre, C.; Cincotti, F.; Kübler, A.; Leeb, R.; Neuper, C.; Müller, K.-R.; Mattia, D.

    2010-01-01

    In recent years, new research has brought the field of electroencephalogram (EEG)-based brain–computer interfacing (BCI) out of its infancy and into a phase of relative maturity through many demonstrated prototypes such as brain-controlled wheelchairs, keyboards, and computer games. With this proof-of-concept phase in the past, the time is now ripe to focus on the development of practical BCI technologies that can be brought out of the lab and into real-world applications. In particular, we focus on the prospect of improving the lives of countless disabled individuals through a combination of BCI technology with existing assistive technologies (AT). In pursuit of more practical BCIs for use outside of the lab, in this paper, we identify four application areas where disabled individuals could greatly benefit from advancements in BCI technology, namely, “Communication and Control”, “Motor Substitution”, “Entertainment”, and “Motor Recovery”. We review the current state of the art and possible future developments, while discussing the main research issues in these four areas. In particular, we expect the most progress in the development of technologies such as hybrid BCI architectures, user–machine adaptation algorithms, the exploitation of users’ mental states for BCI reliability and confidence measures, the incorporation of principles in human–computer interaction (HCI) to improve BCI usability, and the development of novel BCI technology including better EEG devices. PMID:20877434

  6. Genre, technology and embodied interaction: The evolution of digital game genres and motion gaming

    Directory of Open Access Journals (Sweden)

    Andreas Gregersen

    2011-11-01

    Full Text Available Technology has been given relatively little attention in genre theory, but this article argues that material technologies can be important components in genre development. The argument is based on a historically informed analysis of digital games, with special attention paid to home console video games and recent genre developments within this domain commonly referred to as motion gaming. The main point is that digital game genres imply structured embodied activity. A constitutive element of digital game mediation is a control interface geared to player embodiment, and I propose the concept of ‘interaction modes’ to describe the coupling of technology and player embodiment and show how this can be integrated with genre theory. The resulting framework allows for increased attention to continuity and change in game and communication genres, material and digital technologies, and the related interaction modes.

  7. Depression longitudinally mediates the association of appearance concerns to ART non-adherence in HIV-infected individuals with a history of injection drug use.

    Science.gov (United States)

    Blashill, Aaron J; Gordon, Janna R; Safren, Steven A

    2014-02-01

    Appearance concerns are common among HIV-infected individuals, and previous cross-sectional and longitudinal data indicate that these concerns are associated with antiretroviral therapy (ART) non-adherence. However, to date, no known prospective data have explored the mechanism behind this relationship. Thus, the aim of the current study was to test depression severity as a prospective mediator of the relationship between appearance concerns and ART non-adherence in HIV-infected individuals with a history of injection drug use (IDU). Participants were 89 HIV-infected individuals with a history of IDU who participated in a prospective, randomized controlled trial of cognitive behavioral therapy for depression and medication adherence. Clinician-administered measures of depression severity and appearance concerns, along with electronic monitoring of ART non-adherence were included. Data were analyzed using longitudinal linear mixed-level modeling, and mediation was tested via the Monte Carlo Method of Assessing Mediation. Appearance concerns were predictive of depression severity, γ = .31, SE = .076, 95 % CI [.16, .46], t = 4.1, p = .0001, and depression severity was predictive of ART non-adherence, γ = 3.3, SE = 1.3, 95 % CI [.8, 5.8], t = 2.6, p = .01. The effect of appearance concerns on ART non-adherence, however, was significantly mediated by depression severity, γ = 1.02, 95 % CI [.21, 2.1]. Appearance concerns are associated with depression severity, which in turn is associated with ART non-adherence. Integrative interventions addressing appearance concerns, depression and ART adherence are needed, as this is one potential pathway towards worse health outcomes in HIV-infected individuals.

  8. Object-Based Teaching and Learning for a Critical Assessment of Digital Technologies in Arts and Cultural Heritage

    Science.gov (United States)

    Hess, M.; Garside, D.; Nelson, T.; Robson, S.; Weyrich, T.

    2017-08-01

    As cultural sector practice becomes increasingly dependent on digital technologies for the production, display, and dissemination of art and material heritage, it is important that those working in the sector understand the basic scientific principles underpinning these technologies and the social, political and economic implications of exploiting them. The understanding of issues in cultural heritage preservation and digital heritage begins in the education of the future stakeholders and the innovative integration of technologies into the curriculum. This paper gives an example of digital technology skills embedded into a module in the interdisciplinary UCL Bachelor of Arts and Sciences, named "Technologies in Arts and Cultural Heritage", at University College London.

  9. IN A PARALLEL UNIVERSE: HOW ART EXPLOITS TECHNOLOGY

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    Technical innovation in the arts creates new opportunities for perceptual shifts that lead to lasting achievements. One of the most important events took place in the 15th century not far from CERN on the other side of the Alps in Venice. Titian, in one life time, exploited these new material developments to expand the range of expression like no other artist of his generation. Titian was able to harness these new innovations to emerge as the supreme competitor and hustler, a notion that seems very much a part of the modern promotion of art as exemplified by Warhol , Jeff Koons and Damian Hirst. The language of science and technology has created social networks, changed the mediums and the subject of fine art. Fast forward to CERN 2012, the most expensive experiment in the history of science. The knowledge of dark matter will either help confirm, or not, the Standard Model. This information will be part of what Michel Foucault calls "epistemological breaks", shifts in consciousness that change our p...

  10. Dark matter self-interactions from a general spin-0 mediator

    Energy Technology Data Exchange (ETDEWEB)

    Kahlhoefer, Felix; Schmidt-Hoberg, Kai; Wild, Sebastian

    2017-04-15

    Dark matter particles interacting via the exchange of very light spin-0 mediators can have large self-interaction rates and obtain their relic abundance from thermal freeze-out. At the same time, these models face strong bounds from direct and indirect probes of dark matter as well as a number of constraints on the properties of the mediator. We investigate whether these constraints can be consistent with having observable effects from dark matter self-interactions in astrophysical systems. For the case of a mediator with purely scalar couplings we point out the highly relevant impact of low-threshold direct detection experiments like CRESST-II, which essentially rule out the simplest realization of this model. These constraints can be significantly relaxed if the mediator has CP-violating couplings, but then the model faces strong constraints from CMB measurements, which can only be avoided in special regions of parameter space.

  11. Dark matter self-interactions from a general spin-0 mediator

    International Nuclear Information System (INIS)

    Kahlhoefer, Felix; Schmidt-Hoberg, Kai; Wild, Sebastian

    2017-01-01

    Dark matter particles interacting via the exchange of very light spin-0 mediators can have large self-interaction rates and obtain their relic abundance from thermal freeze-out. At the same time, these models face strong bounds from direct and indirect probes of dark matter as well as a number of constraints on the properties of the mediator. We investigate whether these constraints can be consistent with having observable effects from dark matter self-interactions in astrophysical systems. For the case of a mediator with purely scalar couplings we point out the highly relevant impact of low-threshold direct detection experiments like CRESST-II, which essentially rule out the simplest realization of this model. These constraints can be significantly relaxed if the mediator has CP-violating couplings, but then the model faces strong constraints from CMB measurements, which can only be avoided in special regions of parameter space.

  12. Dark matter self-interactions from a general spin-0 mediator

    Energy Technology Data Exchange (ETDEWEB)

    Kahlhoefer, Felix; Schmidt-Hoberg, Kai; Wild, Sebastian, E-mail: felix.kahlhoefer@desy.de, E-mail: kai.schmidt-hoberg@desy.de, E-mail: sebastian.wild@desy.de [DESY, Notkestraße 85, D-22607 Hamburg (Germany)

    2017-08-01

    Dark matter particles interacting via the exchange of very light spin-0 mediators can have large self-interaction rates and obtain their relic abundance from thermal freeze-out. At the same time, these models face strong bounds from direct and indirect probes of dark matter as well as a number of constraints on the properties of the mediator. We investigate whether these constraints can be consistent with having observable effects from dark matter self-interactions in astrophysical systems. For the case of a mediator with purely scalar couplings we point out the highly relevant impact of low-threshold direct detection experiments like CRESST-II, which essentially rule out the simplest realization of this model. These constraints can be significantly relaxed if the mediator has CP-violating couplings, but then the model faces strong constraints from CMB measurements, which can only be avoided in special regions of parameter space.

  13. The Medialogy education - AAU Copenhagen:Where art and creativity meet technology. Special focus on interactive systems design, programming and evaluation in problem based learning.

    OpenAIRE

    Nordahl, Rolf; Serafin, Stefania

    2007-01-01

    In the Medialogy education we attempt to subject some of the common conventions of art to quantitative, scientific experiments to see if they work as intended. Several educational methods are used within the education of Medialogy in order to enable students to make their own connections, filling gaps and create awareness of the pros and cons of working with dogmas within the minefield where art and creativity meet technology. In this talk we will demonstrate our approach through concrete exa...

  14. Decomposition of the Total Effect in the Presence of Multiple Mediators and Interactions.

    Science.gov (United States)

    Bellavia, Andrea; Valeri, Linda

    2018-06-01

    Mediation analysis allows decomposing a total effect into a direct effect of the exposure on the outcome and an indirect effect operating through a number of possible hypothesized pathways. Recent studies have provided formal definitions of direct and indirect effects when multiple mediators are of interest and have described parametric and semiparametric methods for their estimation. Investigating direct and indirect effects with multiple mediators, however, can be challenging in the presence of multiple exposure-mediator and mediator-mediator interactions. In this paper we derive a decomposition of the total effect that unifies mediation and interaction when multiple mediators are present. We illustrate the properties of the proposed framework in a secondary analysis of a pragmatic trial for the treatment of schizophrenia. The decomposition is employed to investigate the interplay of side effects and psychiatric symptoms in explaining the effect of antipsychotic medication on quality of life in schizophrenia patients. Our result offers a valuable tool to identify the proportions of total effect due to mediation and interaction when more than one mediator is present, providing the finest decomposition of the total effect that unifies multiple mediators and interactions.

  15. OBJECT-BASED TEACHING AND LEARNING FOR A CRITICAL ASSESSMENT OF DIGITAL TECHNOLOGIES IN ARTS AND CULTURAL HERITAGE

    Directory of Open Access Journals (Sweden)

    M. Hess

    2017-08-01

    Full Text Available As cultural sector practice becomes increasingly dependent on digital technologies for the production, display, and dissemination of art and material heritage, it is important that those working in the sector understand the basic scientific principles underpinning these technologies and the social, political and economic implications of exploiting them. The understanding of issues in cultural heritage preservation and digital heritage begins in the education of the future stakeholders and the innovative integration of technologies into the curriculum. This paper gives an example of digital technology skills embedded into a module in the interdisciplinary UCL Bachelor of Arts and Sciences, named “Technologies in Arts and Cultural Heritage”, at University College London.

  16. Assisted reproductive technology (ART) in humans: facts and uncertainties.

    Science.gov (United States)

    Ménézo, Y J; Veiga, A; Pouly, J L

    2000-01-15

    Since the first in vitro fertilization (IVF) in human, the number of patients using Assisted Reproductive Technologies (ART) has increased tremendously. ART technologies have increased in number and their spectrum has also widened. The first IVF babies are now more than 20 years old. All the retrospective analyses have demonstrated that the obstetrical and pediatrical impact has not really affected single births. The main problems observed occur with multiple pregnancies, including high costs for the couples and for society. The decrease in the number of embryos transferred has improved the situation and moreover does not impair the final results. IntraCytoplasmic Sperm Injection (ICSI) is a more debatable and questionable technique with a real negative genetic impact. The main problem is chromosome abnormalities more specifically related to the sex chromosomes. The question of a systematic genetic work-up on the patients entering ICSI programs is discussed. No negative impact of cryopreservation has been demonstrated even though some controversy arises from time to time. Pre-implantation Genetic Diagnosis (PGD) is now a interesting tool for patients carrying genetic defects. Blastocyst biopsy now has a future role in reproductive medicine. Gender selection through sperm sorting is also now a reality. As with the other developing bio-technologies related to reproduction, there are ethical questions. The decisions concerning these technologies do not belong solely to scientists but are rather a matter for society to decide.

  17. Mediating factors in martial arts and combat sports: an analysis of the type of martial art, characteristics, and social background of young participants.

    Science.gov (United States)

    Vertonghen, Jikkemien; Theeboom, Marc; Pieter, Willy

    2014-02-01

    To date, most studies regarding the social-psychological effects of martial arts and combat sports (MA&CS) on young people focus on measuring effects without considering mediating factors. The aim of the present study was to analyze three mediating factors that might be influential when examining outcomes of MA&CS for youth (i.e., the type of MA&CS, participants' characteristics, and social background). Young MA&CS participants (N = 477, M age = 14.0 yr., SD = 2.13) practicing judo, aikido, kick-/Thai boxing or karate, as well as their parents (N = 307), were assessed in terms of their goal orientations, aggressiveness, psychosocial behavior, and social background. It was concluded that differences exist in the characteristics and social background of participants depending on the type of MA&CS being practiced. The fact that differences in these mediating factors can be identified indicates that in future research these and possible other mediating factors should be considered when trying to determine social-psychological outcomes of MA&CS.

  18. Thomas DaCosta Kaufmann and Michael North (eds., Mediating Netherlandish Art and Material Culture in Asia

    Directory of Open Access Journals (Sweden)

    Claartje Rasterhoff

    2015-12-01

    Full Text Available Book notice of: Thomas DaCosta Kaufmann and Michael North (eds., Mediating Netherlandish Art and Material Culture in Asia (Amsterdam Studies in the Dutch Golden Age Amsterdam, Amsterdam University Press, 2014. 348 pp. ISBN 978-90-8964-569-2. € 99,00.

  19. REMATERIALIZED TENDENCIES IN MEDIA ART?FROM SILICON TO CARBON-BASED ART

    Directory of Open Access Journals (Sweden)

    DANIEL LÓPEZ DEL RINCÓN

    2013-01-01

    Full Text Available The importance of digitality in Media Art theories consolidated the aesthetic of dematerialization, as it shifted the value of materiality in this field. However, the advent of new forms of technological art, such as Bio Art, which uses laboratory technologies in an aesthetic way to manipulate life, demonstrates the crisis of this paradigm and the trend of rematerialization. This paper investigates the role of materiality, even in the more dematerialized realms of Media Art: the digital technologies. We focus on two art forms that combine new technologies and life sciences: Artificial life, which involves the intangible features of Media Art, and Bio Art, which interprets materiality in a radical manner, by choosing life as the raw material for artistic creation.

  20. REMATERIALIZED TENDENCIES IN MEDIA ART? FROM SILICON TO CARBON-BASED ART

    Directory of Open Access Journals (Sweden)

    Daniel López del Rincón

    2013-01-01

    Full Text Available The importance of digitality in Media Art theories consolidated the aesthetic of dematerialization, as it shifted the value of materiality in this field. However, the advent of new forms of technological art, such as Bio Art, which uses laboratory technologies in an aesthetic way to manipulate life, demonstrates the crisis of this paradigm and the trend of rematerialization. This paper investigates the role of materiality, even in the more dematerialized realms of Media Art: the digital technologies. We focus on two art forms that combine new technologies and life sciences: Artificial life, which involves the intangible features of Media Art, and Bio Art, which interprets materiality in a radical manner, by choosing life as the raw material for artistic creation.

  1. How do dynamic capabilities transform external technologies into firms’ renewed technological resources? – A mediation model

    DEFF Research Database (Denmark)

    Li-Ying, Jason; Wang, Yuandi; Ning, Lutao

    2016-01-01

    microfoundations of dynamic technological capabilities, mediate the relationship between external technology breadth and firms’ technological innovation performance, based on the resource-based view and dynamic capability view. Using a sample of listed Chinese licensee firms, we find that firms must broadly......How externally acquired resources may become valuable, rare, hard-to-imitate, and non-substitute resource bundles through the development of dynamic capabilities? This study proposes and tests a mediation model of how firms’ internal technological diversification and R&D, as two distinctive...... explore external technologies to ignite the dynamism in internal technological diversity and in-house R&D, which play their crucial roles differently to transform and reconfigure firms’ technological resources....

  2. System of Interactions of Social Actors in Public Communication of Science and Technology

    Directory of Open Access Journals (Sweden)

    Miriam Graciela Miquilena

    2010-11-01

    Full Text Available This paper presents the results of a research aimed at explaining the system of interactions of social actors in Public Communication of Science and Technology (PCST, in the context of a social web defined by the novel systems of communication sustained on informational and communication technologies. The study’s theoretical framework highlights the strategic importance of a Public Communication  which focuses on promoting public appropriation of Science and Technology, going beyond the role of Journalism and Science Communication that informs a qualified public, to one that stablishes a bond with policies and decision making in the area, made with participation of international agencies, governments, producers of science and technology, journalists’ associations, educational institutions, and citizens. The research relies on Explicative Methodology. A revision of pertinent bibliography leads to the conclusion that the system of social interactions mediated by personal, interpersonal and grupal global communications, define the relationships in the communicational exchange of the social actor with regard to public communication of science and technology and policies aimed at its appropriation.

  3. Water-mediated ionic interactions in protein structures

    Indian Academy of Sciences (India)

    ISHWARYA( R SARANI( M KIRTI VAISHNAVI and K SEKAR. Supplementary table 1. List of complete water-mediated ionic interactions formed by different combinations of charged atoms and their corresponding occurrences. S. No. Type.

  4. State-of-the-art of fiber-reinforced polymers in additive manufacturing technologies

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; Pedersen, David Bue; Tosello, Guido

    2017-01-01

    Additive manufacturing technologies have received a lot of attention in recent years for their use in multiple materials such as metals, ceramics, and polymers. The aim of this review article is to analyze the technology of fiber-reinforced polymers and its implementation with additive...... manufacturing. This article reviews recent developments, ideas, and state-of-the-art technologies in this field. Moreover, it gives an overview of the materials currently available for fiber-reinforced material technology....

  5. Integrating Technology, Art, and Writing to Create Comic Books

    Science.gov (United States)

    Vega, Edwin S.; Schnakenberg, Heidi L.

    2006-01-01

    In this article, the authors talk about the Summer Safari program that is designed for 9-to 14-year-old students. It targets individuals with an interest in comic books and a penchant for writing stories and/or drawing. The highlight of this multidisciplinary workshop is the seamless integration of writing, fine arts, and computer technology to…

  6. Effects of Synchronous Computer-Mediated Communication and Face-to-Face Interaction on Speaking Skill Development of Iranian EFL Learners

    OpenAIRE

    Hakimeh Shahrokhi Mehr; Masoud Zoghi; Nader Assadi

    2013-01-01

    The traditional form of teaching speaking skill has been via face-to-face (FTF) interaction in the classroom setting. Today in the computer age, the on-line forum can provide a virtual environment for differential communication. The pedagogical system benefits from such technology improvement for teaching foreign languages. This quasi-experimental research aimed at comparing the effects of two instructional strategies: synchronous computer-mediated communication (SCMC) and FTF interaction. Fo...

  7. Study on Multimedia Art Teaching Resources Management System based on Internet Technology

    Directory of Open Access Journals (Sweden)

    Pan Bao Quan

    2016-01-01

    Full Text Available The main technical architecture of art teaching management system was developed on B/S model in order to help implement the network to share teaching resources. System page of Dreamweaver web page was design software, the background for using SQL Server 2000 database design, the use of ASP, ADO data combined with multimedia data transmission technology for art teaching resources system was realized.

  8. An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release

    International Nuclear Information System (INIS)

    Adamik, Barbara; Islam, Aminul; Rouhani, Farshid N.; Hawari, Feras I.; Zhang Jing; Levine, Stewart J.

    2008-01-01

    The type I, 55-kDa tumor necrosis factor receptor (TNFR1) is released to the extracellular space by two mechanisms, the constitutive release of TNFR1 exosome-like vesicles and the inducible proteolytic cleavage of TNFR1 ectodomains. Both pathways appear to be regulated by an interaction between TNFR1 and ARTS-1 (aminopeptidase regulator of TNFR1 shedding). Here, we sought to identify ARTS-1-interacting proteins that modulate TNFR1 release. Co-immunoprecipitation identified an association between ARTS-1 and RBMX (RNA-binding motif gene, X chromosome), a 43-kDa heterogeneous nuclear ribonucleoprotein. RNA interference attenuated RBMX expression, which reduced both the constitutive release of TNFR1 exosome-like vesicles and the IL-1β-mediated inducible proteolytic cleavage of soluble TNFR1 ectodomains. Reciprocally, over-expression of RBMX increased TNFR1 exosome-like vesicle release and the IL-1β-mediated inducible shedding of TNFR1 ectodomains. This identifies RBMX as an ARTS-1-associated protein that regulates both the constitutive release of TNFR1 exosome-like vesicles and the inducible proteolytic cleavage of TNFR1 ectodomains

  9. Positive technology–A powerful partnership between positive psychology and interactive technology. A discussion of potential and challenges.

    Directory of Open Access Journals (Sweden)

    Sarah Diefenbach

    2017-11-01

    Full Text Available Under the umbrella term "positive computing" concepts of positive psychology are transferred to the domain of human-computer interaction (HCI. In an interdisciplinary community psychologist, computer scientists, designers and others are exploring promising ways how to utilize interactive technology to support wellbeing and human flourishing. Along with this, the recent popularity of smartphone apps aiming at the improvement of health behavior, mindfulness and positive routines, suggests the general acceptance of technology as a facilitator of personal development. Given this, there generally seems a high potential for a technology mediated trigger of positive behavior change, especially in context of positive psychology and resource oriented approaches such as solution-focused coaching. At the same time, there is still a lack of well-founded approaches to design such technology which consider its responsible role as an "interactive coach" and systematically integrate the needed expertise of different disciplines. The present article discusses the general potential and particular challenges to support the goals of positive psychology and human desire for self-improvement through interactive technology and highlights critical steps for a successful partnership between both.

  10. Bridging the Arts and Computer Science: Engaging At-Risk Students through the Integration of Music

    Science.gov (United States)

    Moyer, Lisa; Klopfer, Michelle; Ernst, Jeremy V.

    2018-01-01

    Linux Laptop Orchestra (L2Ork), founded in 2009 in the Virginia Tech Music Department's Digital and Interactive Sound & Intermedia Studio, "explores the power of gesture, communal interaction, and the multidimensionality of arts, as well as technology's potential to seamlessly integrate arts and sciences with particular focus on K-12…

  11. Anticipated Ongoing Interaction versus Channel Effects of Relational Communication in Computer-Mediated Interaction.

    Science.gov (United States)

    Walther, Joseph B.

    1994-01-01

    Assesses the related effects of anticipated future interaction and different communication media (computer-mediated versus face-to-face communication) on the communication of relational intimacy and composure. Shows that the assignment of long-term versus short-term partnerships has a larger impact on anticipated future interaction reported by…

  12. Computer technologies of future teachers of fine art training as an object of scientific educational research

    Directory of Open Access Journals (Sweden)

    Bohdan Cherniavskyi

    2017-03-01

    Full Text Available The article deals with computer technology training, highlights the current state ofcomputerization of educational process in teacher training colleges, reveals the specifictechniques of professional training of teachers of fine arts to use computer technology inteaching careers.Key words: Methods of professional training, professional activities, computertechnology training future teachers of Fine Arts, the subject of research.

  13. Creativity and Technology in Mathematics: From Story Telling to Algorithmic with Op'Art

    Science.gov (United States)

    Mercat, Christian; Filho, Pedro Lealdino; El-Demerdash, Mohamed

    2017-01-01

    This article describes some of the results of the European project mcSquared (http://mc2-project.eu/) regarding the use of Op'Art and optical illusion pieces as a tool to foster modeling and creative mathematical thinking in students. We present briefly the c-book technology and some results we got experimenting it. The Op'Art movement, with…

  14. DNA Methylation in Embryo Development: Epigenetic Impact of ART (Assisted Reproductive Technologies).

    Science.gov (United States)

    Canovas, Sebastian; Ross, Pablo J; Kelsey, Gavin; Coy, Pilar

    2017-11-01

    DNA methylation can be considered a component of epigenetic memory with a critical role during embryo development, and which undergoes dramatic reprogramming after fertilization. Though it has been a focus of research for many years, the reprogramming mechanism is still not fully understood. Recent results suggest that absence of maintenance at DNA replication is a major factor, and that there is an unexpected role for TET3-mediated oxidation of 5mC to 5hmC in guarding against de novo methylation. Base-resolution and genome-wide profiling methods are enabling more comprehensive assessments of the extent to which ART might impair DNA methylation reprogramming, and which sequence elements are most vulnerable. Indeed, as we also review here, studies showing the effect of culture media, ovarian stimulation or embryo transfer on the methylation pattern of embryos emphasize the need to face ART-associated defects and search for strategies to mitigate adverse effects on the health of ART-derived children. © 2017 WILEY Periodicals, Inc.

  15. Teaching Responsibly with Technology-Mediated Communication

    Science.gov (United States)

    Veltsos, Jennifer R.; Veltsos, Christophe

    2010-01-01

    Technology-mediated communication, or "new media," such as blogs, Twitter, wikis, and social network sites, can be an endless source of ideas for activities or inspiration for classroom discussion. Many instructors ask students to monitor current events by following keywords and industry leaders on Twitter and reading both corporate and…

  16. Counseling Issues for Gay Men and Lesbians Seeking Assisted Reproductive Technologies (ART)

    Science.gov (United States)

    ... for Reproductive Medicine Counseling issues to discuss with gay men and lesbians seeking assisted reproductive technology (ART) More lesbian, gay, bisexual, and transgender (LGBT) individuals and couples are ...

  17. Performing Re-mediation in Graphical Cyberspace: Mediating Agency, Body and Identity in Virtual Interactional Practices

    DEFF Research Database (Denmark)

    McIlvenny, Paul

    and spectacular multi-media event raises many questions. How do we conceive of the recent developments in media technology and social computing that are impacting on what we have traditionally called 'the mass media'? How is interaction and talk mediated and adapted to new media genres? And how do participants......Promoted as the first academic conference to be held completely in graphical cyberspace, Avatars 98 took place in November 1998. The virtual conference site was built and inhabited using software that supports multi-party presence over the Internet in a simulated, navigable environment. During...... frameworks through the multimedia representations that were 'cast' and 'served' across the Internet. If such a ceremonial event had been broadcast through the institutional medium of television, broadcast talk would have been produced for an eavesdropping 'mass audience'. Instead, the digitally re...

  18. Artificial reproductive technologies (ART) applications in Turkey as viewed by feminists.

    Science.gov (United States)

    Sahinoglu-Pelin, S

    2002-01-01

    Since 1979, a lot of couples have benefited, in terms of having babies, from Artificial Reproductive Technologies (ART). In Turkey, there are presently about 20 centres in existence for this purpose where two approved sets of regulations are in operation; the second being an improved form of the former. In this paper, ART applications in Turkey, as viewed by feminists, will be discussed. During ART, the body of the woman concerned is directly involved. And after every application, the possibility of not having a living baby can adversely affect the physical and psychological state of the woman in question with the trauma being sometimes beyond endurance. In the two sets of approved regulations mentioned above, this application has been questioned in terms of ethics.

  19. Strain mediated tri- and quattro- interactions of adatoms

    OpenAIRE

    Kappus, Wolfgang

    2016-01-01

    Lateral interactions of oxygen adatoms derived from first-principles calculations of the O-Pd(100) system had been claimed to include trio- and quattro terms beside pair interactions. This paper is dedicated to extend an earlier model for substrate strain mediated interactions between adatom pairs to include trio- and quattro terms. While monomers (sitting on high symmetric sites) are supposed to create isotropic stress on the substrate, dimers would create anisotropic stress. The requirement...

  20. Frequency of interaction-mediated triggering of antibiotic production among soil bacteria

    Directory of Open Access Journals (Sweden)

    Olaf eTyc

    2014-10-01

    Full Text Available Certain bacterial species produce antimicrobial compounds only in the presence of a competing species. However little is known on the frequency of interaction-mediated induction of antibiotic compound production in natural communities of soil bacteria. Here we developed a high-throughput method to screen for the production of antimicrobial activity by monocultures and pair-wise combinations of 146 phylogenetically different bacteria isolated from similar soil habitats. Growth responses of two human pathogenic model organisms, Escherichia coli WA321 and Staphylococcus aureus 533R4, were used to monitor antimicrobial activity. From all isolates, 33% showed antimicrobial activity only in monoculture and 42% showed activity only when tested in interactions. More bacterial isolates were active against S. aureus than against E. coli. The frequency of interaction-mediated induction of antimicrobial activity was 6% (154 interactions out of 2798 indicating that only a limited set of species combinations showed such activity. The screening revealed also interaction-mediated suppression of antimicrobial activity for 22% of all combinations tested. Whereas all patterns of antimicrobial activity (non-induced production, induced production and suppression were seen for various bacterial classes, interaction-mediated induction of antimicrobial activity was more frequent for combinations of Flavobacteria and alpha- Proteobacteria. The results of our study give a first indication on the frequency of interference competitive interactions in natural soil bacterial communities which may forms a basis for selection of bacterial groups that are promising for the discovery of novel, cryptic antibiotics.

  1. Self-interacting dark matter with a stable vector mediator

    OpenAIRE

    Duerr, Michael; Schmidt-Hoberg, Kai; Wild, Sebastian

    2018-01-01

    Light vector mediators can naturally induce velocity-dependent dark matter self-interactions while at the same time allowing for the correct dark matter relic abundance via thermal freeze-out. If these mediators subsequently decay into Standard Model states such as electrons or photons however, this is robustly excluded by constraints from the Cosmic Microwave Background. We study to what extent this conclusion can be circumvented if the vector mediator is stable and hence contributes to the ...

  2. Children's aesthetic understanding of photographic art and the quality of art-related parent-child interactions.

    Science.gov (United States)

    Szechter, Lisa E; Liben, Lynn S

    2007-01-01

    This research was designed to examine the quality of children's aesthetic understanding of photographs, observe social interactions between parents and children in this aesthetic domain, and study whether qualitatively different dyadic interactions were associated with children's own aesthetic understanding. Parents and children (7-13 years; 40 dyads) individually completed measures of aesthetic understanding and jointly selected photographs for a souvenir scrapbook. Parents' artistic experience varied widely and was associated with their own performance on aesthetic understanding measures. Children's performance on the individual aesthetic tasks was related to age, but not to parents' art experience nor to the qualities of parent-child discussions of aesthetic concepts. Among both parents and children, artistic experience was associated with aesthetic preferences for photographs.

  3. Real-time Control Mediation in Agile Distributed Software Development

    DEFF Research Database (Denmark)

    Persson, John Stouby; Aaen, Ivan; Mathiassen, Lars

    2008-01-01

    Agile distributed environments pose particular challenges related to control of quality and collaboration in software development. Moreover, while face-to-face interaction is fundamental in agile development, distributed environments must rely extensively on mediated interactions. On this backdrop...... control was mediated over distance by technology through real-time exchanges. Contrary to previous research, the analysis suggests that both formal and informal elements of real-time mediated control were used; that evolving goals and adjustment of expectations were two of the main issues in real......-time mediated control exchanges; and, that the actors, despite distances in space and culture, developed a clan-like pattern mediated by technology to help control quality and collaboration in software development....

  4. Grounded in Theory: Immersing Preservice Teachers in Technology-Mediated Learning

    Science.gov (United States)

    DeGennaro, Donna

    2010-01-01

    The integration of technology into preservice teacher education continues to be emphasized as important. The hope is that if future teachers obtain technology skills they will design meaningful technology-mediated learning experiences for their students. However, gaining technology skills alone does not ensure the ability to envision and employ…

  5. Activating social strategies: Face-to-face interaction in technology-mediated citizen science.

    Science.gov (United States)

    Cappa, Francesco; Laut, Jeffrey; Nov, Oded; Giustiniano, Luca; Porfiri, Maurizio

    2016-11-01

    The use of crowds in research activities by public and private organizations is growing under different forms. Citizen science is a popular means of engaging the general public in research activities led by professional scientists. By involving a large number of amateur scientists, citizen science enables distributed data collection and analysis on a scale that would be otherwise difficult and costly to achieve. While advancements in information technology in the past few decades have fostered the growth of citizen science through online participation, several projects continue to fail due to limited participation. Such web-based projects may isolate the citizen scientists from the researchers. By adopting the perspective of social strategy, we investigate within a measure-manipulate-measure experiment if motivations to participate in a citizen science project can be positively influenced by a face-to-face interaction with the scientists leading the project. Such an interaction provides the participants with the possibility of asking questions on the spot and obtaining a detailed explanation of the citizen science project, its scientific merit, and environmental relevance. Social and cultural factors that moderate the effect brought about by face-to-face interactions on the motivations are also dissected and analyzed. Our findings provide an exploratory insight into a means for motivating crowds to participate in online environmental monitoring projects, also offering possible selection criteria of target audience. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Technological, mediatic and cultural hybridisation: Cultural mediations in the context of globalisation

    Directory of Open Access Journals (Sweden)

    Laan Mendes de Barros

    2009-12-01

    Full Text Available We live in a context of borders that are dissolving in many senses, of the convergence and hybridisation of technologies, mass media and cultures. The context is the resizing of practical time, of movements and links between the local and the global. In these times of interculturality, communication plays a very important role; not so much in its technological media dimension, but particularly in the dynamics of cultural mediations that are dividing off from mediatised relations. This article aims to reflect on the transformations in present-day communication processes, marked by strong movements of hybridisation, as well as examining how to consider interculturality in the context of cultural mediations, based on dialogue between Latin American and French authors. Also, using media material, the article presents illustrations of the Brazilian cultural scene, which is marked by a long history of hybridisation that is filled with intercultural dynamics.

  7. Development of a body motion interactive system with a weight voting mechanism and computer vision technology

    Science.gov (United States)

    Lin, Chern-Sheng; Chen, Chia-Tse; Shei, Hung-Jung; Lay, Yun-Long; Chiu, Chuang-Chien

    2012-09-01

    This study develops a body motion interactive system with computer vision technology. This application combines interactive games, art performing, and exercise training system. Multiple image processing and computer vision technologies are used in this study. The system can calculate the characteristics of an object color, and then perform color segmentation. When there is a wrong action judgment, the system will avoid the error with a weight voting mechanism, which can set the condition score and weight value for the action judgment, and choose the best action judgment from the weight voting mechanism. Finally, this study estimated the reliability of the system in order to make improvements. The results showed that, this method has good effect on accuracy and stability during operations of the human-machine interface of the sports training system.

  8. Whose global art (history?: Ancient art as global art

    Directory of Open Access Journals (Sweden)

    Cynthia Colburn

    2016-12-01

    Full Text Available Discourse on global art or art history arguably dominates the field of art history today in terms of curriculum and research. This discourse cuts across time and space, impacting all art historical specializations, from prehistoric to contemporary, and from Africa to the Americas. Yet, the mainstream theoretical discourse on global art or art history focuses almost explicitly on contemporary and, to a lesser extent, modern art, operating from the premise that only these arts were created in an age of globalization and, thus, emphasize hybridity. This essay seeks to expand the mainstream theoretical discourse regarding global art to pre-modern examples, given that artistic exchange and hybridity dates as early as the prehistoric era all over the world and is not dependent on newer technologies. Indeed, one might argue that the study of pre-modern examples of global art could provide a powerful historical lens through which to analyze contemporary global art.

  9. Enhancing User Experience through Emotional Interaction: Determining Users' Interests in Online Art Collections Using AMARA (Affective Museum of Art Resource Agent)

    Science.gov (United States)

    Park, S. Joon

    2013-01-01

    The need for emotional interaction has already influenced various disciplines and industries, and online museums represent a domain where providing emotional interactions could have a significant impact. Today, online museums lack the appropriate affective and hedonic values necessary to engage art enthusiasts on an emotional level. To address…

  10. Art Engineering and Kinetic Art

    Directory of Open Access Journals (Sweden)

    Barış Yılmaz

    2014-12-01

    Full Text Available Performing an art, either by painting or by sculpturing, requires to be interdisciplinary. When an artist creates his/her work of art, the process he/she realizes is supported by different engineering disciplines. Therefore, especially modern artists need to understand engineering science and this results in transforming artists into engineers. Opportunities provided by technology and science enable artists to expand his/her vision and to improve his/her works. Especially kinetic art has become an approach that combines art with engineering. Kinetic art, which is nourished with varied disciplines, is an excellent example to prove that art is interdisciplinary and to show the relationship between artist/art and engineering.

  11. Health Technology Assessment - science or art?

    Science.gov (United States)

    Hofmann, Bjørn

    2013-01-01

    The founding disciplines of HTA are clearly scientific, and have been firmly based among the natural sciences. However, common definitions of HTA indicate that HTA is something more than the "pure application of science". This article investigates whether this "something" also makes HTA an art. The question of whether HTA is a science or an art is pursued in two specific and historically rich directions. The first is whether HTA is an art in the same way that medicine is described as an art. It has been argued extensively that medicine is based on two different and partly incompatible cultures, i.e., the natural sciences and humanities. Medicine is based on disciplines within the natural sciences, while its value judgments have been placed in the humanities camp. This dichotomy is present in HTA as well, and the first part of the investigation illustrates how HTA is an art in terms of its inherent and constitutive value-judgments. The second part of the science/art-scrutiny leads us to the ancient (Hippocratic) concept of art, téchne, where we find an etymological and a conceptual link between HTA and art. It demonstrates HTA is not an arbitrary process, even though it involves value judgments and relates complex decision making processes. As an art (téchne) HTA has a specific subject matter, requires inquiry and mastery of general rational principles, and is oriented to a specific end. In conclusion, the science-or-art-question makes sense in two specific perspectives, illustrating that HTA is a science based art. This has implications for the practice of HTA, for its education, and for the status of its results.

  12. An Investigation of Interactive, Dialogue-Based Instruction for Undergraduate Art History

    Science.gov (United States)

    Gioffre, Penelope

    2012-01-01

    This paper explores the feasibility and efficacy of incorporating an interactive, discussion-based instructional approach into an undergraduate art history survey course and investigates effects of the new pedagogic strategy on students' demonstrated comprehension and retention of required content. The action research project follows a systematic…

  13. Contemporary challenges to the Church Mission from the perspective of post-modern art and technology

    Directory of Open Access Journals (Sweden)

    Gheorghe Istodor

    2015-11-01

    Full Text Available The secular challenges coming from postmodern art and postmodern technology constitute a serious challenge to be addressed by the mission and life of the Church. The distortion of the Christian Orthodox teaching and the blasphemous trends coming from the contemporary art scene is adding to the distortion of man as God’s special creation from the point of view of genetic engineering, biotechnology, and artificial intelligence, as the core elements of God’s empowerment of man through technology.

  14. Adherence to Technology-Mediated Insomnia Treatment: A Meta-Analysis, Interviews, and Focus Groups

    OpenAIRE

    Horsch, Corine; Lancee, Jaap; Beun, Robbert Jan; Neerincx, Mark A; Brinkman, Willem-Paul

    2015-01-01

    Background: Several technologies have been proposed to support the reduction of insomnia complaints. A user-centered assessment of these technologies could provide insight into underlying factors related to treatment adherence. Objective: Gaining insight into adherence to technology-mediated insomnia treatment as a solid base for improving those adherence rates by applying adherence-enhancing strategies. Methods: Adherence to technology-mediated sleep products was studied in three ways. First...

  15. Art as a Means of Accessing Ourselves. Using Art in Psychotherapy.

    Science.gov (United States)

    d'Errico, Immacolata

    2017-09-01

    Using art in psychotherapy could become an interesting instrument for the cure and the prevention of psychological and psychiatric problems. This belongs to that trend that sees the mediation of art as having big potential to go beyond the spoken word. Everybody knows that our emotions, thoughts, feelings, and so on, are living in the body and speaking through the body, in fact the symbolic dimension (art, music, dance, painting and so on) reconfigures the experience of living. In this form of therapy we use Art as a means of accessing ourselves and opening ourselves up to the world. The forms of artistic mediation that we mainly describe in the paper are the basic elements of tango and performative theatrical technique (Theatre of the Oppressed and Physical Theatre). In the final part of this paper a series of images illustrate specific cases in which the method and its outcomes are described.

  16. Mediated Windows: The Use of Framing and Transparency in Designing for Presence

    Directory of Open Access Journals (Sweden)

    Charlie Gullström

    2014-07-01

    Full Text Available This paper explores the fusion of architecture and media technology that facilitates collaborative practices across spatial extensions: video-mediated spaces. The example presented is a mediated extension of the Museum of National Antiquities in Stockholm to a neighbouring park area and archaeological excavation site in 2008, referred to as a mediated window, or a glass-door. The concepts framing and transparency are used to outline the significance of windows and glazing in architecture and art. The author then considers the potential contribution of architecture in representing the passage from indoors to outdoors and designing for presence. Presence design assumes a contribution from architects to presence research, a currently diversified field, spanning media-space research, cognitive science, interaction design, ubiquitous computing, second-order cybernetics, and computer-supported collaborative work, but in which architecture and artistic practices are less represented.The paper thereby addresses the potential of an extended architectural practice, which incorporates the design of mediated spaces, and outlines presence design as a transdisciplinary practice in which presence research meets architectural design, and spatial and aesthetic conceptual tools, derived from related visual practices, may be productively applied.

  17. The health outcomes of human offspring conceived by assisted reproductive technologies (ART).

    Science.gov (United States)

    Chen, M; Heilbronn, L K

    2017-08-01

    Concerns have been raised about the health and development of children conceived by assisted reproductive technologies (ART) since 1978. Controversially, ART has been linked with adverse obstetric and perinatal outcomes, an increased risk of birth defects, cancers, and growth and development disorders. Emerging evidence suggests that ART treatment may also predispose individuals to an increased risk of chronic ageing related diseases such as obesity, type 2 diabetes and cardiovascular disease. This review will summarize the available evidence on the short-term and long-term health outcomes of ART singletons, as multiple pregnancies after multiple embryos transfer, are associated with low birth weight and preterm delivery, which can separately increase risk of adverse postnatal outcomes, and impact long-term health. We will also examine the potential factors that may contribute to these health risks, and discuss underlying mechanisms, including epigenetic changes that may occur during the preimplantation period and reprogram development in utero, and adult health, later in life. Lastly, this review will consider the future directions with the view to optimize the long-term health of ART children.

  18. Observações sobre o circuito de arte digital no Brasil

    Directory of Open Access Journals (Sweden)

    Gasparetto, Débora Aita

    2015-10-01

    Full Text Available In 2014, O Curto-Circuito da Arte Digital no Brasil [The Short Circuit of Digital Art in Brazil] mapped the spaces for production, distribution, consumption and preservation of digital art in the country. The current text is a selection of that mapping, focusing on artists working at the interface of art-science-technology in projects that involve computability, interactivity, virtuality, immersion and "real time" in research processes related to biotechnology, nanotechnology, physics, computer science, mathematics, engineering, mechanics, robotics, among other areas, interfaced by digital media.

  19. Promising Practices in Higher Education: Art Education and Human Rights Using Information, Communication Technologies (ICT)

    Science.gov (United States)

    Black, Joanna; Cap, Orest

    2014-01-01

    Promising pedagogical practices is described in relation to incorporating ICT (Information, Communication and Technologies) with the study of Human Rights issues in Visual Arts Education for teacher candidates. As part of a course, "Senior Years Art," students at the Faculty of Education, University of Manitoba during 2013-2014…

  20. Effects of Synchronous Computer-Mediated Communication and Face-to-Face Interaction on Speaking Skill Development of Iranian EFL Learners

    Directory of Open Access Journals (Sweden)

    Hakimeh Shahrokhi Mehr

    2013-09-01

    Full Text Available The traditional form of teaching speaking skill has been via face-to-face (FTF interaction in the classroom setting. Today in the computer age, the on-line forum can provide a virtual environment for differential communication. The pedagogical system benefits from such technology improvement for teaching foreign languages. This quasi-experimental research aimed at comparing the effects of two instructional strategies: synchronous computer-mediated communication (SCMC and FTF interaction. For this purpose, 60 EFL learners were selected from a private language institute as the control (n=30 and experimental (n=30 groups. A speaking test, designed by Hughes (2003, was administered as pretest and after a 12-session treatment the same test was administered as the posttest. The result obtained showed that participants taught based on SCMC fared better than those that were taught according to FTF interaction. Based on the findings of the current study, it is recommended that EFL teachers incorporate computer-mediated communication into their pedagogical procedures.

  1. Applications of Modern Analysis Techniques in Searching back Ancient Art Ceramic Technologies

    Directory of Open Access Journals (Sweden)

    Nguyen Quang Liem

    2011-12-01

    Full Text Available This report highlights the promising applications of modern analysis techniques such as Scanning Electron Microsopy, X-ray fluorescence, X-ray diffraction, Raman scattering spectroscopy, and thermal expansion measurement in searching back the ancient art ceramics technologies.

  2. GEOGRAPHICAL EDUCATION MEDIATIZATION AND MEDIASECURITY ISSUES

    Directory of Open Access Journals (Sweden)

    M. R. Arpentieva

    2017-01-01

    Full Text Available The article is devoted to the interaction of legal and moral development of media technologies in the context of geographical education. The article summarizes the experience of the theoretical analysis of mediatization in geographic education, the legal and moral aspects of the disorders and ways of their prevention and correction in the process of educational interaction between teacher and student, between student and teacher, mediated mediatechnologies. It is noted that geographical education in the modern world is education, which is closely associated with the use of media technologies. In other types of education the role of media technologies in improving the quality of education is less obvious, in the field of teaching and learning geography, it speaks very clearly. Therefore, the problems associated with its mediatization, are very important and their solution is particularly compelling. These issues are primarily associated with actively flowing social, economic, political and ideological crisis in many communities and countries of the Earth. Many of them as in the “mirror” are reflected in the sphere of high technologies, including media technologies. The article provides guidance and direction to the correction of violations at the individual and social levels.

  3. The Impact of Ubiquitous Technologies on the Art Museum as Urban [Political] Space

    DEFF Research Database (Denmark)

    Jacobsen, Mogens; Søndergaard, Morten

    art practice. Our hypothesis is that these new domains have a more general existence and ’profile’ in the paradigm of media art – even though the following is based on the process of creating the ‘MAP – Media Art Platform’ at the Museum of Contemporary Art (MFSK) in Roskilde, Denmark, between 2005...... and 2008, a process in which we both were involved as media artist and media art curator, respectively. Our focus in this article is to investigate further the status of these new competencies and roles, and to ask: what are these new domains that emerge with regard to the artist, the software developer......The Museum is part of a ubiquitous framing of cultural production and a common, urban (political) space. In later years, technology has enhanced the ubiquity, as well as challenged the foundation of, the Museum. From this enhancement and challenge, which is transforming the museum itself, new...

  4. Trickle-down effects of supervisor perceptions of interactional justice: a moderated mediation approach.

    Science.gov (United States)

    Ambrose, Maureen L; Schminke, Marshall; Mayer, David M

    2013-07-01

    Supervisors' perceptions of how fairly they are treated by their own supervisors can influence their subordinates' perceptions, attitudes, and behavior. We present a moderated mediation model that demonstrates how work group structure can enhance or constrain these effects. Results show supervisors' perceptions of the fairness of the interactional treatment they receive relate to their subordinates' perceptions of interactional justice climate, and this relationship is stronger in work groups with more organic structures. Furthermore, consistent with the moderated mediation prediction, interactional justice climate mediates the relationship between supervisors' perceptions of interactional justice and outcomes when work group structures are more organic. We discuss the implications of the findings for research on justice and trickle-down effects. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  5. Embedding interaction within a blend of learner centric pedagogy and technology

    Directory of Open Access Journals (Sweden)

    Roisin C. Donnelly

    2009-06-01

    Full Text Available This paper explores the concept and practice of interaction within a blended problem‐based and eLearning module foracademic professional development in higher education. A qualitative study spanning two years of the lived experiences of17 academic staff in a module entitled ‘Designing eLearning’ was considered likely to provide a much‐needed analysis ofcurrent thinking and practice on the potential of interaction. Relevant constructivist theories are applied to face‐to‐faceproblem‐based learning (PBL tutorials, online discussions, focus group interviews and reflective papers. For designers andtutors in blended PBL, it is important to seek best practices for how to combine instructional strategies in classroom andcomputer‐mediated environments that take advantage of the strengths of each and avoid their weaknesses. Specificaspects of interaction (technical, peer, content and the learning experience within blended PBL tutorials are explored toprovide research‐based information about the realities of delivering a PBL module using a variety of relevant and authenticlearning technologies

  6. CELLULAR INTERACTIONS MEDIATED BY GLYCONECTIDS

    Directory of Open Access Journals (Sweden)

    O.Popescu

    1999-01-01

    Full Text Available Cellular interactions involve many types of cell surface molecules and operate via homophilic and/or heterophilic protein-protein and protein-carbohydrate binding. Our investigations in different model-systems (marine invertebrates and mammals have provided direct evidence that a novel class of primordial proteoglycans, named by us gliconectins, can mediate cell adhesion via a new alternative molecular mechanism of polyvalent carbohydrate-carbohydrate binding. Biochemical characterization of isolated and purified glyconectins revealed the presence of specific carbohydrate structures, acidic glycans, different from classical glycosaminoglycans. Such acidic glycans of high molecular weight containing fucose, glucuronic or galacturonic acids, and sulfate groups, originally found in sponges and sea urchin embryos, may represent a new class of carbohydrate carcino-embryonal antigens in mice and humans. Such interactions between biological macromolecules are usually investigated by kinetic binding studies, calorimetric methods, X-ray diffraction, nuclear magnetic resonance, and other spectroscopic analyses. However, these methods do not supply a direct estimation of the intermolecular binding forces that are fundamental for the function of the ligand-receptor association. Recently, we have introduced atomic force microscopy to quantify the binding strength between cell adhesion proteoglycans. Measurement of binding forces intrinsic to cell adhesion proteoglycans is necessary to assess their contribution to the maintenance of the anatomical integrity of multicellular organisms. As a model, we selected the glyconectin 1, a cell adhesion proteoglycan isolated from the marine sponge Microciona prolifera. This glyconectin mediates in vivo cell recognition and aggregation via homophilic, species-specific, polyvalent, and calcium ion-dependent carbohydrate-carbohydrate interactions. Under physiological conditions, an adhesive force of up to 400 piconewtons

  7. Technology-enhanced human interaction in psychotherapy.

    Science.gov (United States)

    Imel, Zac E; Caperton, Derek D; Tanana, Michael; Atkins, David C

    2017-07-01

    Psychotherapy is on the verge of a technology-inspired revolution. The concurrent maturation of communication, signal processing, and machine learning technologies begs an earnest look at how these technologies may be used to improve the quality of psychotherapy. Here, we discuss 3 research domains where technology is likely to have a significant impact: (1) mechanism and process, (2) training and feedback, and (3) technology-mediated treatment modalities. For each domain, we describe current and forthcoming examples of how new technologies may change established applications. Moreover, for each domain we present research questions that touch on theoretical, systemic, and implementation issues. Ultimately, psychotherapy is a decidedly human endeavor, and thus the application of modern technology to therapy must capitalize on-and enhance-our human capacities as counselors, students, and supervisors. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  8. Molecular simulations of lipid-mediated protein-protein interactions

    NARCIS (Netherlands)

    de Meyer, F.J.M.; Venturoli, M.; Smit, B.

    2008-01-01

    Recent experimental results revealed that lipid-mediated interactions due to hydrophobic forces may be important in determining the protein topology after insertion in the membrane, in regulating the protein activity, in protein aggregation and in signal transduction. To gain insight into the

  9. Network support, technology use, depression, and ART adherence among HIV-positive MSM of color.

    Science.gov (United States)

    Holloway, I W; Tan, D; Dunlap, S L; Palmer, L; Beougher, S; Cederbaum, J A

    2017-09-01

    Depression is associated with poor antiretroviral therapy (ART) adherence among people living with HIV/AIDS. This relationship may be moderated by an individual's social network characteristics. Our study sought to examine social network correlates of treatment adherence among HIV-positive men recruited from social service agencies throughout Los Angeles County (N = 150) to inform technology-driven social support interventions for this population. We administered egocentric social network and computer-assisted survey interviews focused on demographic characteristics, health history, depressive symptoms, and ART adherence, where adherence was assessed by the number of reasons participants missed taking their medication, if ever. Significant univariate correlates of adherence were included in a multivariable regression analysis, where the moderating effect of having a network member who reminds participants to take their HIV medication on the relationship between depression and adherence was tested. Over 60% of participants reported clinically significant depressive symptoms; this was significantly associated with lower adherence among those without someone in their social network to remind them about taking their HIV medication, even after adjusting for covariates in an ordinary least squares regression (adjusted mean difference b = -1.61, SE = 0.42, p = 0.0003). Having a network member who reminds participants to take their ART medication significantly ameliorated the negative association between depression and treatment adherence, especially for those reporting greater depressive symptoms (p = 0.0394). Additionally, participants demonstrated high rates of technology use to communicate with social network members. In order to achieve the aims of the National HIV/AIDS Strategy, innovative interventions addressing mental health to improve ART adherence are needed. Network strategies that leverage technology may be helpful for improving ART

  10. Traditional Art in the Age of Multimedia and Network Communications

    Directory of Open Access Journals (Sweden)

    Željko Rutović

    2013-09-01

    Full Text Available The digital age has opened up enormous possibilities of expression, perception and reading of art. Aesthetic criteria immanent to the models of traditional art transforming into a new conceptuality which is in conformity with the techniques of rapid production and distribution. World of multi-network communications and major technological shift resulting in the metamorphosis of the concept and experience of the definition of art. That means that art is outgoing from the traditional framework of standards and ways of expression, ie. aesthetic and values position of the sense of art. Outside the emblematic of the media traditional linear progress, modern network, according to its ontology, deconstructs forced poetics structure formalism, defining the phenomenology innovative problem-solving discourse situated in the self-reflection plurality as a sign of communication currency of man’s perception of (sur real. The multimedia art is in direct way with aesthetic and communication constructs that reformulating the mediating role, it is a dimension of openness and shifting boundaries seen in the image of the antipode of unquestionable durability.

  11. Digital Technology in the Visual Arts Classroom: An [un]Easy Partnership

    Science.gov (United States)

    Wilks, Judith; Cutcher, Alexandra; Wilks, Susan

    2012-01-01

    This article scrutinizes the dichotomy of the uneasy and easy partnerships that exist between digital technology and visual arts education. The claim that by putting computers into schools "we have bought 'one half of a product'... we've bought the infrastructure and the equipment but we haven't bought the educational…

  12. Interactive spatial multimedia for communication of art in the physical museum space

    DEFF Research Database (Denmark)

    Kortbek, Karen Johanne; Grønbæk, Kaj

    2008-01-01

    of the artworks we apply three spatial multimedia techniques where the only interaction device needed is the human body. The three techniques are: 1) spatially bounded audio; 2) floor-based multimedia; 3) multimedia interior. The paper describes the application of these techniques for communication of information...... without disturbing the art works. This has usually been limited to individual audio guides. In our case we strive to achieve holistic and social experiences with seamless transitions between art experience and communication related to the artworks. To reach a holistic experience with minimal disturbance...... in a Mariko Mori exhibition. The multimedia installations and their implementation are described. It is argued that the utilization of the spatial multimedia techniques support holistic and social art experience. The multimedia installations were in function for a three and a half month exhibition period...

  13. The Memory of a Tree; An Interactive Visual Storytelling Installation

    Directory of Open Access Journals (Sweden)

    Hyunjoo Oh

    2012-12-01

    Full Text Available Over the centuries, people have combined fields, leading to the creation of new domains. For example, artists have used technology to widen the range of their medium to express ideas in new ways. Similarly, technology has leveraged art to expand its range of application. Both art and technology continue to inspire innovation in each other. A contemporary example of this process is evident in interactive art era; this article covers this topic focusing on tangible interface pieces. There have been many compelling demonstrations that involve tangible interaction to increase audience interests through their embodied interaction. However, most existing approaches are limited to engaging a user’s immediate, temporary experience with setting some context of the environment with story elements. This article presents an interactive installation that engages the audience, building an immersive environment based on the synergy between embodied interaction and storytelling in a more active and meaningful way. It is based on the belief that tangible interfaces have the potential to convey narratives more meaningfully based on physical interaction and human senses and fundamentally, aims to supply another potential of tangible interfaces to spark further discussion in this area.

  14. The understanding and acceptability of assisted reproductive technology (ART) among infertile women in urban Lagos, Nigeria.

    Science.gov (United States)

    Fabamwo, A O; Akinola, O I

    2013-01-01

    This descriptive study was carried out to assess the awareness and acceptability of Assisted Reproductive Technology (ART) among infertile women in Lagos, Nigeria. Self-administered questionnaires on the knowledge of ART in the women were used. After a brief exposé on ART, questions relating to their attitude were answered. A total of 166 women were studied. Only 51.8% had any knowledge of ART and most of these had poor knowledge. A total of 137 women would embrace ART if offered but 29 would not, for reasons such as religion, fear of side-effects, failure and unaffordable costs. There is a paucity of good knowledge of ART. A significant number of the women would consider ART if offered. There is thus a need to create more awareness about the possibilities offered by ART, as well as instituting low cost ART strategies in developing world countries.

  15. Root signals that mediate mutualistic interactions in the rhizosphere.

    Science.gov (United States)

    Rasmann, Sergio; Turlings, Ted Cj

    2016-08-01

    A recent boom in research on belowground ecology is rapidly revealing a multitude of fascinating interactions, in particular in the rhizosphere. Many of these interactions are mediated by photo-assimilates that are excreted by plant roots. Root exudates are not mere waste products, but serve numerous functions to control abiotic and biotic processes. These functions range from changing the chemical and physical properties of the soil, inhibiting the growth of competing plants, combatting herbivores, and regulating the microbial community. Particularly intriguing are root-released compounds that have evolved to serve mutualistic interactions with soil-dwelling organisms. These mutually beneficial plant-mediated signals are not only of fundamental ecological interest, but also exceedingly important from an agronomical perspective. Here, we attempt to provide an overview of the plant-produced compounds that have so far been implicated in mutualistic interactions. We propose that these mutualistic signals may have evolved from chemical defenses and we point out that they can be (mis)used by specialized pathogens and herbivores. We speculate that many more signals and interactions remain to be uncovered and that a good understanding of the mechanisms and ecological implications can be the basis for exploitation and manipulation of the signals for crop improvement and protection. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Assessment of the State of the Art of Flight Control Technologies as Applicable to Adverse Conditions

    Science.gov (United States)

    Reveley, Mary s.; Briggs, Jeffrey L.; Leone, Karen M.; Kurtoglu, Tolga; Withrow, Colleen A.

    2010-01-01

    Literature from academia, industry, and other Government agencies was surveyed to assess the state of the art in current Integrated Resilient Aircraft Control (IRAC) aircraft technologies. Over 100 papers from 25 conferences from the time period 2004 to 2009 were reviewed. An assessment of the general state of the art in adaptive flight control is summarized first, followed by an assessment of the state of the art as applicable to 13 identified adverse conditions. Specific areas addressed in the general assessment include flight control when compensating for damage or reduced performance, retrofit software upgrades to flight controllers, flight control through engine response, and finally test and validation of new adaptive controllers. The state-of-the-art assessment applicable to the adverse conditions include technologies not specifically related to flight control, but may serve as inputs to a future flight control algorithm. This study illustrates existing gaps and opportunities for additional research by the NASA IRAC Project

  17. MC EMiNEM maps the interaction landscape of the Mediator.

    Directory of Open Access Journals (Sweden)

    Theresa Niederberger

    Full Text Available The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators or repressors to the RNA Polymerase II. The internal network of interactions between Mediator subunits that conveys these signals is largely unknown. Here, we introduce MC EMiNEM, a novel method for the retrieval of functional dependencies between proteins that have pleiotropic effects on mRNA transcription. MC EMiNEM is based on Nested Effects Models (NEMs, a class of probabilistic graphical models that extends the idea of hierarchical clustering. It combines mode-hopping Monte Carlo (MC sampling with an Expectation-Maximization (EM algorithm for NEMs to increase sensitivity compared to existing methods. A meta-analysis of four Mediator perturbation studies in Saccharomyces cerevisiae, three of which are unpublished, provides new insight into the Mediator signaling network. In addition to the known modular organization of the Mediator subunits, MC EMiNEM reveals a hierarchical ordering of its internal information flow, which is putatively transmitted through structural changes within the complex. We identify the N-terminus of Med7 as a peripheral entity, entailing only local structural changes upon perturbation, while the C-terminus of Med7 and Med19 appear to play a central role. MC EMiNEM associates Mediator subunits to most directly affected genes, which, in conjunction with gene set enrichment analysis, allows us to construct an interaction map of Mediator subunits and transcription factors.

  18. MC EMiNEM maps the interaction landscape of the Mediator.

    Science.gov (United States)

    Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C; Martin, Dietmar E; Fröhlich, Holger; Cramer, Patrick; Tresch, Achim

    2012-01-01

    The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators or repressors to the RNA Polymerase II. The internal network of interactions between Mediator subunits that conveys these signals is largely unknown. Here, we introduce MC EMiNEM, a novel method for the retrieval of functional dependencies between proteins that have pleiotropic effects on mRNA transcription. MC EMiNEM is based on Nested Effects Models (NEMs), a class of probabilistic graphical models that extends the idea of hierarchical clustering. It combines mode-hopping Monte Carlo (MC) sampling with an Expectation-Maximization (EM) algorithm for NEMs to increase sensitivity compared to existing methods. A meta-analysis of four Mediator perturbation studies in Saccharomyces cerevisiae, three of which are unpublished, provides new insight into the Mediator signaling network. In addition to the known modular organization of the Mediator subunits, MC EMiNEM reveals a hierarchical ordering of its internal information flow, which is putatively transmitted through structural changes within the complex. We identify the N-terminus of Med7 as a peripheral entity, entailing only local structural changes upon perturbation, while the C-terminus of Med7 and Med19 appear to play a central role. MC EMiNEM associates Mediator subunits to most directly affected genes, which, in conjunction with gene set enrichment analysis, allows us to construct an interaction map of Mediator subunits and transcription factors.

  19. Mathematics for Gifted Students in an Arts- and Technology-Rich Setting

    Science.gov (United States)

    Gadanidis, George; Hughes, Janette; Cordy, Michelle

    2011-01-01

    In this paper we report on a study of a short-term mathematics program for grade 7-8 gifted students that integrated open-ended mathematics tasks with the arts (poetry and drama) and with technology. The program was offered partially online and partially in a classroom setting. The study sought to investigate (a) students' perceptions of their…

  20. Exploring the Mediating Effect of E-social Capital Between Community Members Interaction and Consumer Engagement

    OpenAIRE

    Yan Bingsheng; Li Lihua; Sun Hongtao

    2017-01-01

    This article explored the effect of instrumental interaction and relational interaction on consumer engagement (community engagement and brand engagement) among community members. The mediating effect of E-social capital was investigated as well. The research results showed that: both instrumental interaction and interpersonal interaction promote the formation of E-social capital (online trust and online reciprocity); online trust plays a partial mediating role between community interaction (...

  1. iELM—a web server to explore short linear motif-mediated interactions

    Science.gov (United States)

    Weatheritt, Robert J.; Jehl, Peter; Dinkel, Holger; Gibson, Toby J.

    2012-01-01

    The recent expansion in our knowledge of protein–protein interactions (PPIs) has allowed the annotation and prediction of hundreds of thousands of interactions. However, the function of many of these interactions remains elusive. The interactions of Eukaryotic Linear Motif (iELM) web server provides a resource for predicting the function and positional interface for a subset of interactions mediated by short linear motifs (SLiMs). The iELM prediction algorithm is based on the annotated SLiM classes from the Eukaryotic Linear Motif (ELM) resource and allows users to explore both annotated and user-generated PPI networks for SLiM-mediated interactions. By incorporating the annotated information from the ELM resource, iELM provides functional details of PPIs. This can be used in proteomic analysis, for example, to infer whether an interaction promotes complex formation or degradation. Furthermore, details of the molecular interface of the SLiM-mediated interactions are also predicted. This information is displayed in a fully searchable table, as well as graphically with the modular architecture of the participating proteins extracted from the UniProt and Phospho.ELM resources. A network figure is also presented to aid the interpretation of results. The iELM server supports single protein queries as well as large-scale proteomic submissions and is freely available at http://i.elm.eu.org. PMID:22638578

  2. MOO: Using a Computer Gaming Environment to Teach about Community Arts

    Science.gov (United States)

    Garber, Elizabeth

    2004-01-01

    In this paper, the author discusses the use of an interactive computer technology, "MOO" (Multi-user domain, Object-Oriented), in her art education classes for preservice teachers. A MOO is a text-based environment wherein interactivity is centered on text exchanges made between users based on problems or other materials created by teachers. The…

  3. Visualization of Host-Polerovirus Interaction Topologies Using Protein Interaction Reporter Technology.

    Science.gov (United States)

    DeBlasio, Stacy L; Chavez, Juan D; Alexander, Mariko M; Ramsey, John; Eng, Jimmy K; Mahoney, Jaclyn; Gray, Stewart M; Bruce, James E; Cilia, Michelle

    2016-02-15

    Demonstrating direct interactions between host and virus proteins during infection is a major goal and challenge for the field of virology. Most protein interactions are not binary or easily amenable to structural determination. Using infectious preparations of a polerovirus (Potato leafroll virus [PLRV]) and protein interaction reporter (PIR), a revolutionary technology that couples a mass spectrometric-cleavable chemical cross-linker with high-resolution mass spectrometry, we provide the first report of a host-pathogen protein interaction network that includes data-derived, topological features for every cross-linked site that was identified. We show that PLRV virions have hot spots of protein interaction and multifunctional surface topologies, revealing how these plant viruses maximize their use of binding interfaces. Modeling data, guided by cross-linking constraints, suggest asymmetric packing of the major capsid protein in the virion, which supports previous epitope mapping studies. Protein interaction topologies are conserved with other species in the Luteoviridae and with unrelated viruses in the Herpesviridae and Adenoviridae. Functional analysis of three PLRV-interacting host proteins in planta using a reverse-genetics approach revealed a complex, molecular tug-of-war between host and virus. Structural mimicry and diversifying selection-hallmarks of host-pathogen interactions-were identified within host and viral binding interfaces predicted by our models. These results illuminate the functional diversity of the PLRV-host protein interaction network and demonstrate the usefulness of PIR technology for precision mapping of functional host-pathogen protein interaction topologies. The exterior shape of a plant virus and its interacting host and insect vector proteins determine whether a virus will be transmitted by an insect or infect a specific host. Gaining this information is difficult and requires years of experimentation. We used protein interaction

  4. Tourists' acceptance of advanced technology-based innovations for promoting arts and culture

    NARCIS (Netherlands)

    Pantano, E.; Corvello, V.

    2014-01-01

    Advanced technologies are able to influence tourists' decisions. They can be exploited for attracting touristic flows towards cultural destinations. In particular, virtual tours are new tools based on advanced 3D graphics that can be useful for promoting arts and culture. In this paper, we test

  5. HIV-1 Nef in Macrophage-Mediated Disease Pathogenesis

    Science.gov (United States)

    Lamers, Susanna L.; Fogel, Gary B.; Singer, Elyse J.; Salemi, Marco; Nolan, David J.; Huysentruyt, Leanne C.; McGrath, Michael S.

    2013-01-01

    Combined anti-retroviral therapy (cART) has significantly reduced the number of AIDS-associated illnesses and changed the course of HIV-1 disease in developed countries. Despite the ability of cART to maintain high CD4+ T-cell counts, a number of macrophage-mediated diseases can still occur in HIV-infected subjects. These diseases include lymphoma, metabolic diseases, and HIV-associated neurological disorders. Within macrophages, the HIV-1 regulatory protein “Nef” can modulate surface receptors, interact with signaling pathways, and promote specific environments that contribute to each of these pathologies. Moreover, genetic variation in Nef may also guide the macrophage response. Herein, we review findings relating to the Nef–macrophage interaction and how this relationship contributes to disease pathogenesis. PMID:23215766

  6. Art-mediated peer-to-peer learning of empathy.

    Science.gov (United States)

    Potash, Jordan; Chen, Julie

    2014-08-01

    Making experiential art in a clinical clerkship offers opportunities for students to gain self-awareness and enhance their empathic understanding of patients. The student-created art can be further used as teaching material for other students. The graduating class of 2012 from Ajou University School of Medicine in South Korea was interested in learning about medical humanities initiatives at the Li Ka Shing Faculty of Medicine, University of Hong Kong (HKU), and made an educational visit in May 2012. As part of the core family medicine curriculum, third-year HKU medical students created poetry and art based on their experiences witnessing patients in pain and suffering. Twenty of the artworks and accompanying reflective writing were chosen for an exhibition. The visiting students viewed the exhibit and created their own art based on their emotional response to one piece selected from the exhibit. The combination of viewing art made by their peers and creating art in response resulted in empathic understanding of patient pain and suffering, and an appreciation of holistic care and the value of the doctor-patient relationship. Medical student-generated artwork has the potential to educate both students and professionals on humanistic aspects of medical care. © 2014 John Wiley & Sons Ltd.

  7. Parent-child mediated learning interactions as determinants of cognitive modifiability: recent research and future directions.

    Science.gov (United States)

    Tzuriel, D

    1999-05-01

    The main objectives of this article are to describe the effects of mediated learning experience (MLE) strategies in mother-child interactions on the child's cognitive modifiability, the effects of distal factors (e.g., socioeconomic status, mother's intelligence, child's personality) on MLE interactions, and the effects of situational variables on MLE processes. Methodological aspects of measurement of MLE interactions and of cognitive modifiability, using a dynamic assessment approach, are discussed. Studies with infants showed that the quality of mother-infant MLE interactions predict later cognitive functioning and that MLE patterns and children's cognitive performance change as a result of intervention programs. Studies with preschool and school-aged children showed that MLE interactions predict cognitive modifiability and that distal factors predict MLE interactions but not the child's cognitive modifiability. The child's cognitive modifiability was predicted by MLE interactions in a structured but not in a free-play situation. Mediation for transcendence (e.g., teaching rules and generalizations) appeared to be the strongest predictor of children's cognitive modifiability. Discussion of future research includes the consideration of a holistic transactional approach, which refers to MLE processes, personality, and motivational-affective factors, the cultural context of mediation, perception of the whole family as a mediational unit, and the "mediational normative scripts."

  8. A social-technological epistemology of clinical decision-making as mediated by imaging.

    Science.gov (United States)

    van Baalen, Sophie; Carusi, Annamaria; Sabroe, Ian; Kiely, David G

    2017-10-01

    In recent years there has been growing attention to the epistemology of clinical decision-making, but most studies have taken the individual physicians as the central object of analysis. In this paper we argue that knowing in current medical practice has an inherently social character and that imaging plays a mediating role in these practices. We have analyzed clinical decision-making within a medical expert team involved in diagnosis and treatment of patients with pulmonary hypertension (PH), a rare disease requiring multidisciplinary team involvement in diagnosis and management. Within our field study, we conducted observations, interviews, video tasks, and a panel discussion. Decision-making in the PH clinic involves combining evidence from heterogeneous sources into a cohesive framing of a patient, in which interpretations of the different sources can be made consistent with each other. Because pieces of evidence are generated by people with different expertise and interpretation and adjustments take place in interaction between different experts, we argue that this process is socially distributed. Multidisciplinary team meetings are an important place where information is shared, discussed, interpreted, and adjusted, allowing for a collective way of seeing and a shared language to be developed. We demonstrate this with an example of image processing in the PH service, an instance in which knowledge is distributed over multiple people who play a crucial role in generating an evaluation of right heart function. Finally, we argue that images fulfill a mediating role in distributed knowing in 3 ways: first, as enablers or tools in acquiring information; second, as communication facilitators; and third, as pervasively framing the epistemic domain. With this study of clinical decision-making in diagnosis and treatment of PH, we have shown that clinical decision-making is highly social and mediated by technologies. The epistemology of clinical decision-making needs

  9. A conserved pattern in plant-mediated interactions between herbivores

    OpenAIRE

    Lu Jing; Robert Christelle A. M.; Lou Yonggen; Erb Matthias

    2016-01-01

    Abstract Plant?mediated interactions between herbivores are important determinants of community structure and plant performance in natural and agricultural systems. Current research suggests that the outcome of the interactions is determined by herbivore and plant identity, which may result in stochastic patterns that impede adaptive evolution and agricultural exploitation. However, few studies have systemically investigated specificity versus general patterns in a given plant system by varyi...

  10. Implications of the cognitive dimension of art in artistic scenic education. Some contributions for the teacher in scenic arts at the high school level.

    Directory of Open Access Journals (Sweden)

    Carolina Merchan Price

    2010-11-01

    Full Text Available In this work we explore the contributions proposed by Arthur Efland (especially those of his book Art and Cognition, with the aim of broadening the statements of the academic programmes in performing arts as a curriculum area in the scholar plan, and also within the frame of teacher training. In this perspective, we consider the concept of cognition towards those experiences and subsequent learning in which the body plays a central role as mediator in the process of understanding of the world itself. We also discuss during the analysis the role of the emotions in thought processes. In this sense, we propose to use this new perspective of complementary interaction between the emotional and intellectual dimensions to discuss the concepts of creation, appreciation and understanding, typical of artistic fields and their teaching. We propose this complementary interaction as a fundamental process of the encounter of arts, in the dynamics of development in the school. In the conclusions, we open the possibility of a need to redefine the conceptual axes to train teachers in performing arts, articulating specific disciplinary knowledge of performing arts with the needs of the scholar project itself, particularly those linked to the social and individual development of the person in the frame of basic and intermediate school.

  11. Antiretroviral treatment adherence as a mediating factor between psychosocial variables and HIV viral load.

    Science.gov (United States)

    Attonito, Jennifer; Dévieux, Jessy G; Lerner, Brenda D G; Hospital, Michelle M; Rosenberg, Rhonda

    2014-01-01

    Psychosocial factors may directly impact HIV health measures such as viral load (VL) whether or not patients are taking antiretroviral treatment (ART) consistently. Structural equation modeling plus Baron and Kenny's (1986) four-step approach were used to test a mediated model predicting VL among 246 HIV-infected adults who were on ART. Exogenous variables were social support, barriers to adherence, and stress. Moderators were alcohol use, marijuana use, and neurocognitive impairment. A small positive association between marijuana use and ART adherence approached significance. Only barriers to adherence predicted a decrease in adherence rates and an increase in VL. No other factors were significantly associated with either VL or adherence, and no interaction effects between exogenous variables and moderators were identified. The association between barriers to adherence and VL was partially mediated by ART adherence. Findings provide modest support for a direct link between psychosocial variables and a virologic response to ART. Copyright © 2014 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

  12. Association of assisted reproductive technology (ART) treatment and parental infertility diagnosis with autism in ART-conceived children.

    Science.gov (United States)

    Kissin, D M; Zhang, Y; Boulet, S L; Fountain, C; Bearman, P; Schieve, L; Yeargin-Allsopp, M; Jamieson, D J

    2015-02-01

    Are assisted reproductive technology (ART) treatment factors or infertility diagnoses associated with autism among ART-conceived children? Our study suggests that the incidence of autism diagnosis in ART-conceived children during the first 5 years of life was higher when intracytoplasmic sperm injection (ICSI) was used compared with conventional IVF, and lower when parents had unexplained infertility (among singletons) or tubal factor infertility (among multiples) compared with other types of infertility. Some studies found an increased risk of autism among ART-conceived infants compared with spontaneously-conceived infants. However, few studies, and none in the USA, have examined the associations between types of ART procedures and parental infertility diagnoses with autism among ART-conceived children. Population-based retrospective cohort study using linkages between National ART Surveillance System (NASS) data for 1996-2006, California Birth Certificate data for 1997-2006, and California Department of Developmental Services (DDS) Autism Caseload data for 1997-2011. All live born ART-conceived infants born in California in 1997-2006 (n = 42 383) with 5-year observation period were included in the study. We assessed the annual incidence of autism diagnosis documented in DDS, which includes information on the vast majority of persons with autism in California, and the association of autism diagnosis with ART treatment factors and infertility diagnoses. Among ART-conceived singletons born in California between 1997 and 2006, the incidence of autism diagnosis remained at ∼0.8% (P for trend 0.19) and was lower with parental diagnosis of unexplained infertility (adjusted hazard risk ratio [aHRR]; 95% confidence interval: 0.38; 0.15-0.94) and higher when ICSI was used (aHRR 1.65; 1.08-2.52), when compared with cases without these patient and treatment characteristics. Among ART-conceived multiples, the incidence of autism diagnosis between 1997 and 2006 remained at

  13. Virtual Reality Technologies and the Creative Arts in the Areas of Disability, Therapy, Health, and Rehabilitation

    DEFF Research Database (Denmark)

    Cobb, S. V. G.; Brooks, Anthony Lewis; Sharkey, P. M.

    2013-01-01

    A key theme in the ArtAbilitation conferences is the relationship between 6 sound, movement, and art, and how these can be used for rehabilitation and/or 7 expression by individuals who may have limited access to conventional communi- 8 cation. The development of VR environments and interactive...

  14. Health Technology Assessment – science or art?

    Science.gov (United States)

    Hofmann, Bjørn

    2013-01-01

    The founding disciplines of HTA are clearly scientific, and have been firmly based among the natural sciences. However, common definitions of HTA indicate that HTA is something more than the “pure application of science”. This article investigates whether this “something” also makes HTA an art. The question of whether HTA is a science or an art is pursued in two specific and historically rich directions. The first is whether HTA is an art in the same way that medicine is described as an art. It has been argued extensively that medicine is based on two different and partly incompatible cultures, i.e., the natural sciences and humanities. Medicine is based on disciplines within the natural sciences, while its value judgments have been placed in the humanities camp. This dichotomy is present in HTA as well, and the first part of the investigation illustrates how HTA is an art in terms of its inherent and constitutive value-judgments. The second part of the science/art-scrutiny leads us to the ancient (Hippocratic) concept of art, téchne, where we find an etymological and a conceptual link between HTA and art. It demonstrates HTA is not an arbitrary process, even though it involves value judgments and relates complex decision making processes. As an art (téchne) HTA has a specific subject matter, requires inquiry and mastery of general rational principles, and is oriented to a specific end. In conclusion, the science-or-art-question makes sense in two specific perspectives, illustrating that HTA is a science based art. This has implications for the practice of HTA, for its education, and for the status of its results. PMID:23935761

  15. Direct detection signatures of self-interacting dark matter with a light mediator

    International Nuclear Information System (INIS)

    Nobile, Eugenio Del; Kaplinghat, Manoj; Yu, Hai-Bo

    2015-01-01

    Self-interacting dark matter (SIDM) is a simple and well-motivated scenario that could explain long-standing puzzles in structure formation on small scales. If the required self-interaction arises through a light mediator (with mass ∼ 10 MeV) in the dark sector, this new particle must be unstable to avoid overclosing the universe. The decay of the light mediator could happen due to a weak coupling of the hidden and visible sectors, providing new signatures for direct detection experiments. The SIDM nuclear recoil spectrum is more peaked towards low energies compared to the usual case of contact interactions, because the mediator mass is comparable to the momentum transfer of nuclear recoils. We show that the SIDM signal could be distinguished from that of DM particles with contact interactions by considering the time-average energy spectrum in experiments employing different target materials, or the average and modulated spectra in a single experiment. Using current limits from LUX and SuperCDMS, we also derive strong bounds on the mixing parameter between hidden and visible sector

  16. Surface-state mediated three-adsorbate interaction: exact and numerical results and simple asymptotic expression

    International Nuclear Information System (INIS)

    Hyldgaard, Per; Einstein, T.L.

    2003-01-01

    The interaction energy of three adsorbates on a surface consists of the sum of the three-pair interactions plus a trio contribution produced primarily by interference of electrons which traverse the entire perimeter, d 123 , of the three-adsorbate cluster. Here, we investigate this three-adatom interaction when mediated by the isotropic Shockley surface-state band found on noble-metal (1 1 1) surfaces, extending work on pair interactions. Our experimentally testable result depends on the s-wave phase-shift, characterizing the standing-wave patterns seen in scanning-tunneling microscopy (STM) images. Compared with the adsorbate-pair interactions, and in contrast to bulk-mediated interactions, the trio contribution exhibits a slightly weaker amplitude and a slightly faster asymptotic envelope decay, d 123 -5/2 . It also has a different but well-defined oscillation period dependent on d 123 and little dependence on the shape of the cluster. We finally compare the asymptotic description with exact model calculations assuming short-range interactions, which are viable even in the non-asymptotic range (when not outweighed by bulk-mediated interactions)

  17. Luz, arte, ciência... ação! Lights, art, science - action!

    Directory of Open Access Journals (Sweden)

    Thelma Lopes

    2005-01-01

    Full Text Available O principal objetivo do presente artigo é refletir sobre as principais interações entre teatro, ciência e tecnologia, ao longo da história do teatro, e discutir, a partir de nossa experiência no Ciência em Cena, espaço integrante do Museu da Vida, de que modos essas interações podem estar presentes no cotidiano de um museu de ciências. A palavra 'ciência' deve ser compreendida aqui em sentido amplo, englobando não apenas as ciências naturais, mas também as ciências humanas, assim como a palavra 'tecnologia' deve ser associada à ciência aplicada. Arte e ciência serão entendidas como processos criativos, como formas de representação do mundo e expressão do conhecimento humano.The article offers some reflections on the main interactions between theater, science, and technology down through the history of theater. Based on our experience at "Science in the Spotlight", part of the Casa de Oswaldo Cruz's Museum of Life, we discuss how these interactions can be part of a science museum's daily activities. We use the word 'science' in its broad sense, encompassing not only the natural but human sciences as well; likewise, we use the word 'technology' as it relates to applied science. Art and science are understood here as creative processes, as ways of representing the world and expressing human knowledge.

  18. Leptogenesis and composite heavy neutrinos with gauge-mediated interactions

    Energy Technology Data Exchange (ETDEWEB)

    Biondini, S. [University of Bern, AEC, Institute for Theoretical Physics, Bern (Switzerland); Panella, O. [Istituto Nazionale di Fisica Nucleare, Sezione di Perugia, Perugia (Italy)

    2017-09-15

    Leptogenesis is an appealing framework to account for the baryon asymmetry in the universe. To this end physics beyond the standard model is demanded. In this paper we investigate the possibility to attain successful leptogenesis with composite Majorana neutrinos. We work in the framework of effective gauge-mediated and contact interactions without any reference to an underlying compositeness theory. This approach is the one adopted in all current experimental searches for composite fermions at colliders. In the case of gauge-mediated interactions, we calculate the CP asymmetry in heavy composite neutrino decays. Both the direct and the indirect CP asymmetry are derived and resonant leptogenesis is also discussed. We find that the Sakharov conditions can be met and, for some choice of the parameters, the correct order of magnitude of the baryon asymmetry is reproduced. (orig.)

  19. Trait-mediated trophic interactions: is foraging theory keeping up?

    Science.gov (United States)

    Railsback, Steven F; Harvey, Bret C

    2013-02-01

    Many ecologists believe that there is a lack of foraging theory that works in community contexts, for populations of unique individuals each making trade-offs between food and risk that are subject to feedbacks from behavior of others. Such theory is necessary to reproduce the trait-mediated trophic interactions now recognized as widespread and strong. Game theory can address feedbacks but does not provide foraging theory for unique individuals in variable environments. 'State- and prediction-based theory' (SPT) is a new approach that combines existing trade-off methods with routine updating: individuals regularly predict future food availability and risk from current conditions to optimize a fitness measure. SPT can reproduce a variety of realistic foraging behaviors and trait-mediated trophic interactions with feedbacks, even when the environment is unpredictable. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Modelling and simulation SSM: latest state of the art technology

    CSIR Research Space (South Africa)

    Jahajeeah, N

    2005-10-01

    Full Text Available as one phase ? One Phase model ?Wider volume solid fraction 0 – 1 ? Implementation in Power Law Cut-Off Model (PLCO) of Procast Supporting the Manufacturing and Materials Industry in its quest for global competitiveness Assumptions of the PLCO Model... and Materials Industry in its quest for global competitiveness Modelling and Simulation SSM Latest state of the art technology N Jahajeeah Supporting the Manufacturing and Materials Industry in its quest for global competitiveness BEHAVIOUR OF THIXOTROPIC...

  1. Visual art appreciation in Nigeria: The Zaria art society experience ...

    African Journals Online (AJOL)

    There is no doubt that one of the greatest creative impetuses injected into Nigerian art was made possible by, among other things, the activities of the first art institution in Nigeria to award a Diploma certificate in art, Nigerian College of Arts, Science and Technology (NCAST). NCAST started in 1953/54 at their Ibadan branch ...

  2. Student Views of Technology-Mediated Written Corrective Feedback

    DEFF Research Database (Denmark)

    Kjærgaard, Hanne Wacher

    2017-01-01

    and practices concerning the specific – and time-consuming – language-teacher activity of providing WCF and 2) potential changes in student attitudes when technology is used to mediate the feedback. At the core of the study is an eight-month intervention which was carried out with three teachers of English...

  3. Phytohormone mediation of interactions between herbivores and plant pathogens

    NARCIS (Netherlands)

    Lazebnik, J.; Frago, E.; Dicke, M.; Loon, van J.J.A.

    2014-01-01

    Induced plant defenses against either pathogens or herbivore attackers are regulated by phytohormones. These phytohormones are increasingly recognized as important mediators of interactions between organisms associated with plants. In this review, we discuss the role of plant defense hormones in

  4. Adherence to Technology-Mediated Insomnia Treatment: A Meta-Analysis, Interviews, and Focus Groups.

    Science.gov (United States)

    Horsch, Corine; Lancee, Jaap; Beun, Robbert Jan; Neerincx, Mark A; Brinkman, Willem-Paul

    2015-09-04

    Several technologies have been proposed to support the reduction of insomnia complaints. A user-centered assessment of these technologies could provide insight into underlying factors related to treatment adherence. Gaining insight into adherence to technology-mediated insomnia treatment as a solid base for improving those adherence rates by applying adherence-enhancing strategies. Adherence to technology-mediated sleep products was studied in three ways. First, a meta-analysis was performed to investigate adherence rates in technology-mediated insomnia therapy. Several databases were queried for technology-mediated insomnia treatments. After inclusion and exclusion steps, data from 18 studies were retrieved and aggregated to find an average adherence rate. Next, 15 semistructured interviews about sleep-support technologies were conducted to investigate perceived adherence. Lastly, several scenarios were written about the usage of a virtual sleep coach that could support adherence rates. The scenarios were discussed in six different focus groups consisting of potential users (n=15), sleep experts (n=7), and coaches (n=9). From the meta-analysis, average treatment adherence appeared to be approximately 52% (95% CI 43%-61%) for technology-mediated insomnia treatments. This means that, on average, half of the treatment exercises were not executed, suggesting there is a substantial need for adherence and room for improvement in this area. However, the users in the interviews believed they adhered quite well to their sleep products. Users mentioned relying on personal commitment (ie, willpower) for therapy adherence. Participants of the focus groups reconfirmed their belief in the effectiveness of personal commitment, which they regarded as more effective than adherence-enhancing strategies. Although adherence rates for insomnia interventions indicate extensive room for improvement, users might not consider adherence to be a problem; they believe willpower to be an

  5. Outreach with Team eS Through Science Festivals and Interactive Art Installations

    Science.gov (United States)

    Yoho, Amanda; Starkman, Glenn

    2014-03-01

    The Team eS project aims to acclimate (pre)teens to scientific concepts subtly, with fun, accessible, and engaging art and activities hosted at public community festivals, online at a dedicated website, and using social media. Our festivals will be centered around an interactive art installation inspired by a scientific concept. We hope to provide a positive experience inspired by science that these teens can reflect upon when encountering similar concepts in the future, especially in settings like a classroom where fear and anxiety can cloud interest or performance. We want to empower teens to not feel lost or out of the loop - we want to remove the fear of facing science.

  6. State of the Art in HIV Drug Resistance: Science and Technology Knowledge Gap.

    Science.gov (United States)

    Boucher, Charles A; Bobkova, Marina R; Geretti, Anna Maria; Hung, Chien-Ching; Kaiser, Rolf; Marcelin, Anne-Geneviève; Streinu-Cercel, Adrian; van Wyk, Jean; Dorr, Pat; Vandamme, Anne-Mieke

    2018-01-01

    Resistance to antiretroviral therapy (ART) threatens the efficacy of human immunodeficiency virus type 1 (HIV-1) treatment. We present a review of knowledge gaps in the science and technologies of acquired HIV-1 drug resistance (HIVDR) in an effort to facilitate research, scientific exchange, and progress in clinical management. The expert authorship of this review convened to identify data gaps that exist in the field of HIVDR and discuss their clinical implications. A subsequent literature review of trials and current practices was carried out to provide supporting evidence. Several gaps were identified across HIVDR science and technology. A summary of the major gaps is presented, with an expert discussion of their implications within the context of the wider field. Crucial to optimizing the use of ART will be improved understanding of protease inhibitors and, in particular, integrase strand transfer inhibitors (INSTI) in the context of HIVDR. Limited experience with INSTI represents an important knowledge gap in HIV resistance science. Utilizing such knowledge in a clinical setting relies on accurate testing and analysis of resistance-associated mutations. As next-generation sequencing becomes more widely available, a gap in the interpretation of data is the lack of a defined, clinically relevant threshold of minority variants. Further research will provide evidence on where such thresholds lie and how they can be most effectively applied. Expert discussion identified a series of gaps in our knowledge of HIVDR. Addressing prefsuch gaps through further research and characterization will facilitate the optimal use of ART therapies and technologies.

  7. Using E-Learning Portfolio Technology To Support Visual Art Learning

    Directory of Open Access Journals (Sweden)

    Greer Jones-Woodham

    2009-08-01

    Full Text Available Inspired by self-directed learning (SDL theories, this paper uses learning portfolios as a reflective practice to improve student learning and develop personal responsibility, growth and autonomy in learning in a Visual Arts course. Students use PowerPoint presentations to demonstrate their concepts by creating folders that are linked to e-portfolios on the University website. This paper establishes the role of learning e-portfolios to improve teaching and learning as a model of reflection, collaboration and documentation in the making of art as a self-directed process. These portfolios link students' creative thinking to their conceptual frameworks. They also establish a process of inquiry using journals to map students' processes through their reflections and peer feedback. This practice argues that learning e-portfolios in studio art not only depends on a set of objectives whose means are justified by an agreed end but also depends on a practice that engages students' reflection about their actions while in their art- making practice. Using the principles of the maker as the intuitive and reflective practitioner, the making as the process in which the learning e-portfolios communicate the process and conceptual frameworks of learning and the eventual product, and the made as evidence of that learning in light of progress made, this paper demonstrates that learning-in-action and reflecting-in and-on-action are driven by self-direction. With technology, students bring their learning context to bear with the use of SDL. Students' use of PowerPoint program technology in making their portfolios is systematic and builds on students' competencies as this process guides students' beliefs and actions about their work that is based on theory and concepts in response to a visual culture that is Trinidad and Tobago. Students' self–directed art-making process as a self directed learning, models the process of articulated learning. Communicating about

  8. Information sensing and interactive technology of Internet of Things

    Science.gov (United States)

    Xiao, Zhiliang

    2017-11-01

    With the rapid development of economic, the Internet of Things based on Internet technology is more and more concerned by all circles of society, and the Internet of Things begins to penetrate into various fields of society. The Internet of things is an extension of the Internet, the difference between the Internet and the Internet of Things is that the purpose of things aims to achieve the exchange and exchange of information and data, contract the people and goods through a variety of technologies and equipment from items to items. Information perception and interaction technology are two very important technologies in the development of things, but also is the important technology in the history of the development of network technology. This paper briefly analyzes the characteristics of the original information perception, and the difference between the interactive technology of the Internet of Things and the human-computer interaction technology. On this basis, this paper mainly elaborates from the two aspects of information perception and interactive technology.

  9. Attracting pedestrians’ attention using interaction technology

    OpenAIRE

    Mellquist, Michael

    2016-01-01

    The technology and marketing channels to display and broadcast advertisements are ever changing; this has led to the change of many forms of advertisements. Public advertisements have not changed as drastically as many others and can therefore be seen as out-dated. In this paper a prototype of an interactive advertisement with a dynamic user flow is presented where focus has been on attracting attention. Different interaction technologies have been discussed and compared. A Kinect sensor has ...

  10. Social interaction in type 2 diabetes computer-mediated environments: How inherent features of the channels influence peer-to-peer interaction.

    Science.gov (United States)

    Lewinski, Allison A; Fisher, Edwin B

    2016-06-01

    Interventions via the internet provide support to individuals managing chronic illness. The purpose of this integrative review was to determine how the features of a computer-mediated environment influence social interactions among individuals with type 2 diabetes. A combination of MeSH and keyword terms, based on the cognates of three broad groupings: social interaction, computer-mediated environments, and chronic illness, was used to search the PubMed, PsychInfo, Sociology Research Database, and Cumulative Index to Nursing and Allied Health Literature databases. Eleven articles met the inclusion criteria. Computer-mediated environments enhance an individual's ability to interact with peers while increasing the convenience of obtaining personalized support. A matrix, focused on social interaction among peers, identified themes across all articles, and five characteristics emerged: (1) the presence of synchronous and asynchronous communication, (2) the ability to connect with similar peers, (3) the presence or absence of a moderator, (4) personalization of feedback regarding individual progress and self-management, and (5) the ability of individuals to maintain choice during participation. Individuals interact with peers to obtain relevant, situation-specific information and knowledge about managing their own care. Computer-mediated environments facilitate the ability of individuals to exchange this information despite temporal or geographical barriers that may be present, thus improving T2D self-management. © The Author(s) 2015.

  11. MC EMiNEM maps the interaction landscape of the Mediator

    OpenAIRE

    Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C.; Martin, Dietmar E.; Fröhlich, Holger; Cramer, Patrick; Tresch, Achim

    2012-01-01

    The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators or repressors to the RNA Polymerase II. The internal network of interactions between Mediator subunits that conveys these signals is largely unknown. Here, we introduce MC EMiNEM, a novel method for the retrieval of functional dependencies between...

  12. Transporter-mediated natural product–drug interactions for the treatment of cardiovascular diseases

    Directory of Open Access Journals (Sweden)

    Weibin Zha

    2018-04-01

    Full Text Available The growing use of natural products in cardiovascular (CV patients has been greatly raising the concerns about potential natural product–CV drug interactions. Some of these may lead to unexpected cardiovascular adverse effects and it is, therefore, essential to identify or predict potential natural product–CV drug interactions, and to understand the underlying mechanisms. Drug transporters are important determinants for the pharmacokinetics of drugs and alterations of drug transport has been recognized as one of the major causes of natural product–drug interactions. In last two decades, many CV drugs (e.g., angiotensin II receptor blockers, beta-blockers and statins have been identified to be substrates and inhibitors of the solute carrier (SLC transporters and the ATP-binding cassette (ABC transporters, which are two major transporter superfamilies. Meanwhile, in vitro and in vivo studies indicate that a growing number of natural products showed cardioprotective effects (e.g., gingko biloba, danshen and their active ingredients are also substrates and inhibitors of drug transporters. Thus, to understand transporter-mediated natural product–CV drug interactions is important and some transporter-mediated interactions have already shown to have clinical relevance. In this review, we review the current knowledge on the role of ABC and SLC transporters in CV therapy, as well as transporter modulation by natural products used in CV diseases and their induced natural product–CV drug interactions through alterations of drug transport. We hope our review will aid in a comprehensive summary of transporter-mediated natural product–CV drug interactions and help public and physicians understand these type of interactions. Keywords: Cardiovascular drugs, Natural products, Drug transporters, Natural product–drug interaction, Pharmacokinetics

  13. The Significance of a Body in Contemporary Arts

    Directory of Open Access Journals (Sweden)

    Emmanouela Vogiatzaki

    2016-04-01

    Full Text Available This paper discusses the role and significance of a body in Performance Art. Considering that Art reflects social, cultural and sometimes political realities, we identify types of messages that an artwork using advanced technological might transmit to us, spectators or artists. This paper focusses on the Cyborg Theatre, whereby the technology is its inherent element without which the performance could not happen. Such a technological performance cannot occur without a body. We refer here to a cyborg body as a human organism extended with mechanical parts, which integrate non organic components in order to gain meaning within the artwork. By focusing on such a theatrical performance, we observe a relationship developing between the performer and the spectator. This is an unusual interaction, which deserves our attention. We claim that both the performer and the spectator take part in a social event that does not only represent societal realities, but also indicates future ones.

  14. Developmental outcomes of Japanese children born through Assisted Reproductive Technology (ART) in toddlerhood.

    Science.gov (United States)

    Aoki, Sayaka; Hashimoto, Keiji; Ogawa, Kohei; Horikawa, Reiko; Sago, Haruhiko

    2018-05-01

    This study aimed to investigate developmental outcomes of Japanese babies born through Assisted Reproductive Technology (ART) at ages 2 and 3. The data were gathered from 1085 children in a hospital-based cohort study conducted in Japan. The children's level of development was assessed through a parent-rated questionnaire, the Kinder Infant Development Scale, which consists of nine developmental domains. We compared the development of children born through ART and those born naturally by conducting analyses of covariance. For the analyses, the effect of maternal age, family income, parental education and multiple birth were controlled for. At 24 months, no significant difference was found between children born through ART and those born naturally in development in any domain. At 36 months, a significant difference was found in development of Receptive language (F (1, 845) = 6.148, P = 0.013), Expressive language (F (1, 845) = 4.060, P = 0.044) and Language concept (F (1, 845) = 6.968, P = 0.008). For these domains, children born through ART had a significantly higher developmental age compared to children born naturally. At age 2, no significant difference was found between the children born through ART and those born naturally in nine developmental domains, although at age 3, the children born through ART showed significantly better language development than the children born naturally. © 2018 Japan Society of Obstetrics and Gynecology.

  15. Interactive Ways of Becoming a Specialist Fine Art of the Ukrainian Danube Region

    Directory of Open Access Journals (Sweden)

    Ivan Pastyr

    2016-08-01

    Full Text Available In modern conditions the method of education is especially effective if it is built on the intensification of mental activity and is aimed at developing a creative personality. The study presents a system of interactive ways of becoming a specialist in Izmail State Liberal Arts University.

  16. The agency of patients and carers in medical care and self-care technologies for interacting with doctors.

    Science.gov (United States)

    Nunes, Francisco; Andersen, Tariq; Fitzpatrick, Geraldine

    2017-06-01

    People living with Parkinson's disease engage in self-care for most of the time but, two or three times a year, they meet with doctors to re-evaluate the condition and adjust treatment. Patients and (informal) carers participate actively in these encounters, but their engagement might change as new patient-centred technologies are integrated into healthcare infrastructures. Drawing on a qualitative study that used observations and interviews to investigate consultations, and digital ethnography to understand interactions in an online community, we describe how patients and carers living with Parkinson's participate in the diagnosis and treatment decisions, engage in discussions to learn about certain topics, and address inappropriate medication. We contrast their engagement with a review of self-care technologies that support interactions with doctors, to investigate how these artefacts may influence the agency of patients and carers. Finally, we discuss design ideas for improving the participation of patients and carers in technology-mediated scenarios.

  17. State-of-the-art computer technologies used to train nuclear specialists and to conduct research

    International Nuclear Information System (INIS)

    Korovin, Yu.A.; Tikhonenko, A.V.

    2011-01-01

    The paper discusses innovative methods used in the process of training nuclear specialists and conducting research which are based on state-of-the-art computer technologies. The approach proposed makes wide use of mathematical modeling and state-of-the-art programming techniques. It is based on the development, improvement and application of problem-oriented computer codes to support the teaching process and to solve fundamental and applied problems of nuclear physics and nuclear engineering.

  18. Technology-Mediated Interventions and Quality of Life for Persons Living with HIV/AIDS. A Systematic Review.

    Science.gov (United States)

    Cho, Hwayoung; Iribarren, Sarah; Schnall, Rebecca

    2017-04-12

    As HIV/AIDS is considered a chronic disease; quality of life (QoL) has become an important focus for researchers and healthcare providers. Technology-mediated interventions have demonstrated improved clinical effectiveness in outcomes, such as viral suppression, for persons living with HIV/AIDS (PLWH). However, the evidence to support the impact of these interventions on QoL is lacking. The aim of this paper was to assess the impact of technology-mediated interventions on QoL and to identify the instruments used to measure the QoL of PLWH. For this review we followed the PRISMA guidelines. A literature search was conducted in PubMed, CINAHL, Cochrane, and EMBASE databases in April 2016. Inclusion criteria limited articles to those with technology-mediated interventions as compared to usual care; articles with the population defined as HIV-infected patients; and articles with QoL measured as a health outcome in randomized controlled trials. The Cochrane Collaboration Risk of Bias Tool was used to assess study quality. Of the 1,554 peer-reviewed articles returned in the searches, 10 met the inclusion criteria. This systematic review identified four types of technology-mediated interventions and two types of QoL instruments used to examine the impact of technology-mediated interventions on PLWH. Four studies of technology-mediated interventions resulted in improvement in QoL. Four studies considered QoL as a secondary outcome and resulted in a negative or neutral impact on QoL. Overall, four studies had a low risk of bias, one study had a moderate risk of bias, and the other five studies had a high risk of bias. The evidence to support the improvement of QoL using technology-mediated interventions is insufficient. This lack of research highlights the need for increased study of QoL as an outcome measure and the need for consistent measures to better understand the role of technology-mediated interventions in improving QoL for PLWH.

  19. Adherence to technology-mediated insomnia treatment: a meta-analysis, interviews, and focus groups

    NARCIS (Netherlands)

    Horsch, C.; Lancee, J.; Beun, R.J.; Neerincx, M.A.; Brinkman, W.-P.

    2015-01-01

    Background: Several technologies have been proposed to support the reduction of insomnia complaints. A user-centered assessment of these technologies could provide insight into underlying factors related to treatment adherence. Objective: Gaining insight into adherence to technology-mediated

  20. Effect modification, interaction and mediation: an overview of theoretical insights for clinical investigators

    Directory of Open Access Journals (Sweden)

    Corraini P

    2017-06-01

    Full Text Available Priscila Corraini,1 Morten Olsen,1 Lars Pedersen,1 Olaf M Dekkers,1,2 Jan P Vandenbroucke1–3 1Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Leiden University Medical Center, Leiden, the Netherlands; 3Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK Abstract: We revisited the three interrelated epidemiological concepts of effect modification, interaction and mediation for clinical investigators and examined their applicability when using research databases. The standard methods that are available to assess interaction, effect modification and mediation are explained and exemplified. For each concept, we first give a simple “best-case” example from a randomized controlled trial, followed by a structurally similar example from an observational study using research databases. Our explanation of the examples is based on recent theoretical developments and insights in the context of large health care databases. Terminology is sometimes ambiguous for what constitutes effect modification and interaction. The strong assumptions underlying the assessment of interaction, and particularly mediation, require clinicians and epidemiologists to take extra care when conducting observational studies in the context of health care databases. These strong assumptions may limit the applicability of interaction and mediation assessments, at least until the biases and limitations of these assessments when using large research databases are clarified. Keywords: methods, epidemiology, effect modifiers, stratified analyses, health care administrative claims

  1. State-of-the-art technologies of gallium oxide power devices

    Science.gov (United States)

    Higashiwaki, Masataka; Kuramata, Akito; Murakami, Hisashi; Kumagai, Yoshinao

    2017-08-01

    Gallium oxide (Ga2 O3 ) has gained increased attention for power devices due to its superior material properties and the availability of economical device-quality native substrates. This review illustrates recent advances in Ga2 O3 device technologies, beginning with an overview of the social circumstances that motivate the development of new-generation switching devices. Following an introduction to the material properties of Ga2 O3 from the viewpoint of power electronics, growth technologies of Ga2 O3 bulk single crystals and epitaxial thin films are discussed. The fabrication and performance of state-of-the-art Ga2 O3 transistors and diodes are then described. We conclude by identifying the directions and challenges of Ga2 O3 power device development in the near future.

  2. PXR as a mediator of herb–drug interaction

    Directory of Open Access Journals (Sweden)

    Brett C. Hogle

    2018-04-01

    Full Text Available Medicinal herbs have been a part of human medicine for thousands of years. The herb–drug interaction is an extension of drug–drug interaction, in which the consumptions of herbs cause alterations in the metabolism of drugs the patients happen to take at the same time. The pregnane X receptor (PXR has been established as one of the most important transcriptional factors that regulate the expression of phase I enzymes, phase II enzymes, and drug transporters in the xenobiotic responses. Since its initial discovery, PXR has been implicated in multiple herb–drug interactions that can lead to alterations of the drug's pharmacokinetic properties and cause fluctuating therapeutic efficacies, possibly leading to complications. Regions of the world that heavily incorporate herbalism into their primary health care and people turning to alternative medicines as a personal choice could be at risk for adverse reactions or unintended results from these interactions. This article is intended to highlight our understanding of the PXR-mediated herb–drug interactions. Keywords: Drug metabolism, Herb–drug interaction, PXR, St. John's Wort, Xenobiotics

  3. Individual versus Interactive Task-Based Performance through Voice-Based Computer-Mediated Communication

    Science.gov (United States)

    Granena, Gisela

    2016-01-01

    Interaction is a necessary condition for second language (L2) learning (Long, 1980, 1996). Research in computer-mediated communication has shown that interaction opportunities make learners pay attention to form in a variety of ways that promote L2 learning. This research has mostly investigated text-based rather than voice-based interaction. The…

  4. Transporter-mediated natural product-drug interactions for the treatment of cardiovascular diseases.

    Science.gov (United States)

    Zha, Weibin

    2018-04-01

    The growing use of natural products in cardiovascular (CV) patients has been greatly raising the concerns about potential natural product-CV drug interactions. Some of these may lead to unexpected cardiovascular adverse effects and it is, therefore, essential to identify or predict potential natural product-CV drug interactions, and to understand the underlying mechanisms. Drug transporters are important determinants for the pharmacokinetics of drugs and alterations of drug transport has been recognized as one of the major causes of natural product-drug interactions. In last two decades, many CV drugs (e.g., angiotensin II receptor blockers, beta-blockers and statins) have been identified to be substrates and inhibitors of the solute carrier (SLC) transporters and the ATP-binding cassette (ABC) transporters, which are two major transporter superfamilies. Meanwhile, in vitro and in vivo studies indicate that a growing number of natural products showed cardioprotective effects (e.g., gingko biloba, danshen and their active ingredients) are also substrates and inhibitors of drug transporters. Thus, to understand transporter-mediated natural product-CV drug interactions is important and some transporter-mediated interactions have already shown to have clinical relevance. In this review, we review the current knowledge on the role of ABC and SLC transporters in CV therapy, as well as transporter modulation by natural products used in CV diseases and their induced natural product-CV drug interactions through alterations of drug transport. We hope our review will aid in a comprehensive summary of transporter-mediated natural product-CV drug interactions and help public and physicians understand these type of interactions. Copyright © 2017. Published by Elsevier B.V.

  5. In Silico Medicine: Social, Technological and Symbolic Mediation

    Directory of Open Access Journals (Sweden)

    Annamaria Carusi

    2016-06-01

    Full Text Available In silico medicine is still forging a road for itself in the current biomedical landscape. Discursively and rhetorically, it is using a three-way positioning, first, deploying discourses of personalised medicine, second, extending the 3Rs from animal to clinical research, and third, aligning its methods with experimental methods. The discursive and rhetorical positioning in promotions and statements of the programme gives us insight into the sociability of the scientific labour of advancing the programme. Its progress depends on complex social, institutional and technological conditions which are not external to its epistemology, but intricately interwoven with it. This article sets out to show that this is the case through an analysis of the process of computational modelling that is at the core of its epistemology. In this paper I show that the very notion of ‘model’ needs to be re-thought for in silico medicine (as indeed, for most forms of computational modelling, and propose a replacement, in the form of the ‘Model-Simulation-Experiment-System’ or MSE-system, which is simultaneously an epistemological, social and technological system. I argue that the MSE-system is radically mediated by social relations, technologies and symbolic systems. We need now to understand how such mediations operate effectively in the construction of robust MSE-systems.

  6. Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros

    Science.gov (United States)

    Valeri, Linda; VanderWeele, Tyler J.

    2012-01-01

    Mediation analysis is a useful and widely employed approach to studies in the field of psychology and in the social and biomedical sciences. The contributions of this paper are several-fold. First we seek to bring the developments in mediation analysis for non linear models within the counterfactual framework to the psychology audience in an accessible format and compare the sorts of inferences about mediation that are possible in the presence of exposure-mediator interaction when using a counterfactual versus the standard statistical approach. Second, the work by VanderWeele and Vansteelandt (2009, 2010) is extended here to allow for dichotomous mediators and count outcomes. Third, we provide SAS and SPSS macros to implement all of these mediation analysis techniques automatically and we compare the types of inferences about mediation that are allowed by a variety of software macros. PMID:23379553

  7. Female Obesity and Clinical Outcomes of Assisted Reproductive Technologies (ART): an Updated Systematic Review and Meta-analysis

    OpenAIRE

    Heidar Heidari Khoei

    2016-01-01

    Assisted Reproductive Technology (ART) has been developed to be used for reproductive-age women with primary and secondary infertilities. Obesity is a worldwide epidemic for both women and men and a major global health concern. The direct effect of Body Mass Index (BMI) increase on the outcomes of ART is still unclear. This study aimed to carry out a systematic review of the available scientific evidence to assess the effects of obesity on the clinical outcome of ART treatment. Numerous studi...

  8. State-of-the-art report for the instrumentation and control technology based on the nuclear-information technology convergence

    International Nuclear Information System (INIS)

    Kwon, Kee Choon; Kim, Chang Hwoi; Lee, Dong Young; Lee, Cheol Kwon; Lee, Hyun Chul

    2011-12-01

    As digitalized the instrumentation and control systems in nuclear power plants, in the past that were implemented in an analog system or circuit for monitoring, control and protection, most of the them is implemented in embedded software based on hardware platform. Digital instrumentation and control system hardware platforms and a digital safety systems have developed in Korea. The fundamental technology of the software part of MMIS (Man-Machine Interface System) has achieved the localization. But in order to secure our global competitiveness, in the -based software, the source of the content areas / It is needed to develop core technologies of the software and contents areas based on the nuclear-IT convergence technology. In this report, the IT technology centered for the characteristics of embedded software applied to nuclear power is described. Also state-of-the-art IT technologies that will converge to nuclear power plants are mentioned

  9. A Review of Peer-Mediated Social Interaction Interventions for Students with Autism in Inclusive Settings

    Science.gov (United States)

    Watkins, Laci; O'Reilly, Mark; Kuhn, Michelle; Gevarter, Cindy; Lancioni, Giulio E.; Sigafoos, Jeff; Lang, Russell

    2015-01-01

    This review addresses the use of peer-mediated interventions (PMI) to improve the social interaction skills of students with autism spectrum disorder (ASD) in inclusive settings. The purpose of this review is to (a) identify the characteristics and components of peer-mediated social interaction interventions, (b) evaluate the effectiveness of PMI…

  10. The identity of functional diversity in communication mediated by technology

    Directory of Open Access Journals (Sweden)

    Carmen Montalba-Ocaña

    2017-12-01

    Full Text Available The subject matter of the research presented below gravitates on the ontological change imposed by technology in humans. In particular, development of assistive technologies applied to alternative communication systems represents an interesting example of how this technology works on the social relationships, communication, and how this mediation modifies the self-image and social image of the users. This study focuses on people with cerebral palsy or neuronal degenerative disease and the identity transformation suffering to be able to communicate with autonomous tech support. In this way, the hypotheses to be faced in this study are: technology (paradoxically humanizes.

  11. Computer Games and Art

    Directory of Open Access Journals (Sweden)

    Anton Sukhov

    2015-10-01

    Full Text Available This article devoted to the search of relevant sources (primary and secondary and characteristics of computer games that allow to include them in the field of art (such as the creation of artistic games, computer graphics, active interaction with other forms of art, signs of spiritual aesthetic act, own temporality of computer games, “aesthetic illusion”, interactivity. In general, modern computer games can be attributed to commercial art and popular culture (blockbuster games and to elite forms of contemporary media art (author’s games, visionary games.

  12. Art and soul: powerful and powerless art in Singapore

    OpenAIRE

    T C Chang

    2008-01-01

    Public art in urban areas offers a window on a city’s soul. Art in the form of sculptures, monuments, and other creative expressions can inform us of the ways artists think of the urban environment, the goals of policy makers in art installations, and the way members of the public interact with art and with each other in the city. Taking Singapore as a case study, I argue that contemporary public art has the power to inform place identity and inspire community aspirations. Unlike the hard pow...

  13. Technology in precision viticulture: a state of the art review

    Directory of Open Access Journals (Sweden)

    Matese A

    2015-05-01

    Full Text Available Alessandro Matese,1 Salvatore Filippo Di Gennaro1,2 1Institute of Biometeorology, National Research Council (IBIMET-CNR, Florence, Italy; 2Department of Agricultural, Food and Environmental Sciences, University of Perugia, Perugia, Italy Abstract: Precision viticulture aims to maximize the oenological potential of vineyards. This is especially true in regions where the high quality standards of wine production justify the adoption of site-specific management practices to simultaneously increase both quality and yield. The introduction of new technologies for supporting vineyard management allows the efficiency and quality of production to be improved and, at the same time, reduces the environmental impact. The rapid evolution of information communication technologies and geographical science offers enormous potential for the development of optimized solutions for distributed information for precision viticulture. Recent technological developments have allowed useful tools to be elaborated that help in the monitoring and control of many aspects of vine growth. Precision viticulture thus seeks to exploit the widest range of available observations to describe the vineyard spatial variability with high resolution, and provide recommendations to improve management efficiency in terms of quality, production, and sustainability. This review presents a brief outline of state of the art of technologies in precision viticulture. It is divided in two sections, the first focusing on monitoring technologies such as geolocating and remote and proximal sensing; the second focuses on variable-rate technologies and the new agricultural robots. Keywords: remote sensing, proximal sensing, variable-rate technology, robot 

  14. The Role of Executive Functioning and Technological Anxiety (FOMO in College Course Performance as Mediated by Technology Usage and Multitasking Habits

    Directory of Open Access Journals (Sweden)

    Larry D. Rosen

    2017-12-01

    Full Text Available This study investigated how technology use impacts academic performance. A proposed model postulated that academic performance could be predicted by a cognitive independent variable-executive functioning problems-and an affective independent variable-technological anxiety or FOMO (fear of missing out-mediated by how students choose to use technology. An unobtrusive smartphone application called “Instant Quantified Self” monitored daily smartphone unlocks and daily minutes of use. Other mediators included self-reported smartphone use, self-observed studying attention, self-reported multitasking preference, and a classroom digital metacognition tool that assessed the student’s ability to understand the ramifications of technology use in the classroom that is not relevant to the learning process. Two hundred sixteen participants collected an average of 56 days of “Instant” application data, demonstrating that their smartphone was unlocked more than 60 times a day for three to four minutes each time for a total of 220 daily minutes of use. Results indicated that executive functioning problems predicted academic course performance mediated by studying attention and a single classroom digital metacognition subscale concerning availability of strategies of when to use mobile phones during lectures. FOMO predicted performance directly as well as mediated by a second classroom digital metacognition concerning attitudes toward mobile phone use during lectures. Implications for college students and professors include increasing metacognition about technology use in the classroom and taking “tech breaks” to reduce technology anxiety.

  15. Editorial: Expressive Interactive Systems That Tell a Story

    NARCIS (Netherlands)

    Reidsma, Dennis; Volpe, Gualtiero; Volpe, G; Camurri, A.; Camurri, Antonio; Nijholt, Antinus

    2015-01-01

    This special issue brings together selected, extended contributions from the Fourth Conference on Intelligent Technologies for Interactive Entertainment (INTETAIN 2011), with a special focus on research concerning the application of new technologies in the field of arts and culture. Since 2005, the

  16. Solar education combining art, history, science and technology at archaeological sites in Italy

    Energy Technology Data Exchange (ETDEWEB)

    Silvi, C.; Ferro, P. [ISES (Italy); Ceccarini, T. [Educational Section - State Superintendence of Archaeological Monuments in Rome (Italy)

    2004-07-01

    ''Solar Art and Solar Technologies'' and ''Solar Energy by studying Ancient Architecture'' laboratory promoted by ISES ITALIA and the Educational Section of the State Superintendence of Archaeological Monuments in Rome involved from 2000 to 2004 roughly 1000 schoolchildren, 20 teachers and five archaeologists. For its innovative character and its special approach to solar education, the exhibition ''Solar Art and Technologies'' has been acknowledged among the 50 best projects of the ''2001 Energy Globe Award.'' The program has been continuously improved and has broadened its educational reach beyond schoolchildren. The experiences made at the archaeological sites from the energy point of view lead to new research projects and initiatives on solar energy at the archaeological sites during the excavations, while exploring historical sources, and at the involved schools. A seminar on ''Solar energy and the built environment in past civilizations'' will be held at the end of May 2004 to review historical sources and the most recent archaeological discoveries that have relation with solar architecture and technology. The seminar will also address the possible participation of historians and archaeologists in the history sessions planned at ISES 2005 (www.swc2005.org). (orig.)

  17. Exploring the Mediating Effect of E-social Capital Between Community Members Interaction and Consumer Engagement

    Directory of Open Access Journals (Sweden)

    Yan Bingsheng

    2017-01-01

    Full Text Available This article explored the effect of instrumental interaction and relational interaction on consumer engagement (community engagement and brand engagement among community members. The mediating effect of E-social capital was investigated as well. The research results showed that: both instrumental interaction and interpersonal interaction promote the formation of E-social capital (online trust and online reciprocity; online trust plays a partial mediating role between community interaction (instrumental interaction, relational interaction and community engagement, but the influence of online reciprocity on community engagement is not significant; community engagement leads to brand engagement. The findings enrich the theories of brand community and consumer engagement and contribute to the virtual community management.

  18. Technology Corner: Dating of Electronic Hardware for Prior Art Investigations

    Directory of Open Access Journals (Sweden)

    Sellam Ismail

    2012-03-01

    Full Text Available In many legal matters, specifically patent litigation, determining and authenticating the date of computer hardware or other electronic products or components is often key to establishing the item as legitimate evidence of prior art. Such evidence can be used to buttress claims of technologies available or of events transpiring by or at a particular date.In 1945, the Electronics Industry Association published a standard, EIA 476-A, standardized in the reference Source and Date Code Marking (Electronic Industries Association, 1988.(see PDF for full tech corner

  19. Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros.

    Science.gov (United States)

    Valeri, Linda; Vanderweele, Tyler J

    2013-06-01

    Mediation analysis is a useful and widely employed approach to studies in the field of psychology and in the social and biomedical sciences. The contributions of this article are several-fold. First we seek to bring the developments in mediation analysis for nonlinear models within the counterfactual framework to the psychology audience in an accessible format and compare the sorts of inferences about mediation that are possible in the presence of exposure-mediator interaction when using a counterfactual versus the standard statistical approach. Second, the work by VanderWeele and Vansteelandt (2009, 2010) is extended here to allow for dichotomous mediators and count outcomes. Third, we provide SAS and SPSS macros to implement all of these mediation analysis techniques automatically, and we compare the types of inferences about mediation that are allowed by a variety of software macros. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  20. The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

    DEFF Research Database (Denmark)

    Elmlund, Hans; Baraznenok, Vera; Lindahl, Martin

    2006-01-01

    CDK8 (cyclin-dependent kinase 8), along with CycC, Med12, and Med13, form a repressive module (the Cdk8 module) that prevents RNA polymerase II (pol II) interactions with Mediator. Here, we report that the ability of the Cdk8 module to prevent pol II interactions is independent of the Cdk8......-dependent kinase activity. We use electron microscopy and single-particle reconstruction to demonstrate that the Cdk8 module forms a distinct structural entity that binds to the head and middle region of Mediator, thereby sterically blocking interactions with pol II....

  1. Intrathymic laminin-mediated interactions: role in T cell migration and development

    Directory of Open Access Journals (Sweden)

    Wilson eSavino

    2015-11-01

    Full Text Available Intrathymic T cell differentiation is a key process for the development and maintenance of cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We have proposed a multivectorial model for describing intrathymic thymocyte migration. One of the individual vectors comprises interactions mediated by laminins, a heterotrimeric protein family of the extracellular matrix. Several laminins are expressed in the thymus, being produced by microenvironmental cells, particularly thymic epithelial cells. Also, thymocytes and epithelial cells express integrin-type laminin receptors. Functionally, it has been reported that the dy/dy mutant mouse (lacking the laminin isoform 211 exhibits defective thymocyte differentiation. Several data show haptotactic effects of laminins upon thymocytes, as well as their adhesion on thymic epithelial cells; both effects being prevented by anti-laminin or anti-laminin receptor antibodies. Interestingly, laminin synergizes with chemokines to enhance thymocyte migration, whereas classe-3 semaphorins and B ephrins, which exhibit chemorepulsive effects in the thymus, downregulate laminin-mediated migratory responses of thymocytes. More recently, we showed that knocking down the ITGA6 gene (which encodes the α6 integrin chain of laminin receptors in human thymic epithelial cells, modulates a large number of cell-migration related genes, and results in changes of adhesion pattern of thymocytes onto the thymic epithelium. Overall, laminin-mediated interactions can be placed at the cross-road of the multivectorial process of thymocyte migration, with a direct influence per se, as well as by modulating other molecular interactions associated with the intrathymic trafficking events.

  2. KAJIAN METAMORFOSIS PERFORMANCE ART SERTA ASPEK SOSIALNYA

    Directory of Open Access Journals (Sweden)

    Satriana Didiek Isnanta

    2006-01-01

    Full Text Available In the middle of recent development of Indonesian contemporary fine arts world, primarily works regarding the development of technology, New Media Art is one of examples. In the arts context, its uses are often understood as an offer of novel possibility in creating or experiencing the arts. One of them is the metamorphoses of performance art to be multimedia performance, and last metamorphoses into video performance. Video performance, was born out of long history of performance art progress around 1909 through the manifesto of Futurist group in Paris, whose members were poets, painters, and theater players, by using human body as a medium, performance art did dematerialization within art. Video performance in its presentation, perceived that human body was not anymore to be its part, however, what emerged then was virtual body. The existence of body was not really actual, however, its presence could be felt from the visual display coming out from a projector. Here, performance art has been mediated and metamorphosed. In addition, the problems of art and technological fusion promoting the metamorphoses of performance art to be video performance like mentioned above, this writing also discusses social aspects in the line with the emergence and development of performance art in Indonesia. At first, performance art as a process of making aware and resistance arts by deconstructing social reality and the state of being established of the fine arts itself. Second, the ambient media phenomenon in the global advertising practice (including Indonesia distracting struggle direction of performance art “genue” from the process of making aware media into “kitsch” art as a frontline point of advertising for market interest. Abstract in Bahasa Indonesia: Dalam perkembangan dunia seni rupa kontemporer Indonesia dewasa ini, khususnya karya-karya yang bersinggungan dengan perkembangan teknologi, New Media Art (seni media baru adalah salah satu contohnya

  3. The Role of Art in Emotional-Moral Reflection on Risky and Controversial Technologies : the Case of BNCI

    NARCIS (Netherlands)

    Roeser, S.; Alfano, V.R.; Nevejan, Caroline

    2018-01-01

    In this article, we explore the role that art can play in ethical reflection on risky and controversial technologies. New technologies often give rise to societal controversies about their potential risks and benefits. Over the last decades, social scientists, psychologists, and philosophers have

  4. Mediation Analysis with Multiple Mediators.

    Science.gov (United States)

    VanderWeele, T J; Vansteelandt, S

    2014-01-01

    Recent advances in the causal inference literature on mediation have extended traditional approaches to direct and indirect effects to settings that allow for interactions and non-linearities. In this paper, these approaches from causal inference are further extended to settings in which multiple mediators may be of interest. Two analytic approaches, one based on regression and one based on weighting are proposed to estimate the effect mediated through multiple mediators and the effects through other pathways. The approaches proposed here accommodate exposure-mediator interactions and, to a certain extent, mediator-mediator interactions as well. The methods handle binary or continuous mediators and binary, continuous or count outcomes. When the mediators affect one another, the strategy of trying to assess direct and indirect effects one mediator at a time will in general fail; the approach given in this paper can still be used. A characterization is moreover given as to when the sum of the mediated effects for multiple mediators considered separately will be equal to the mediated effect of all of the mediators considered jointly. The approach proposed in this paper is robust to unmeasured common causes of two or more mediators.

  5. Interactive displays natural human-interface technologies

    CERN Document Server

    Bhowmik, Achintya K

    2014-01-01

    One of the first books to provide an in-depth discussion of the technologies, applications and trends in the rapidly emerging field of interactive displays (touch, gesture & voice) The book will cover the technologies, applications and trends in the field of interactive displays, namely interfaces based on touch, gesture and voice and those using a combination of these technologies. The book will be split into 4 main parts with each being dedicated to a specific user interface. Part 1 ''Touch Interfaces'' will provide a review of the currently deployed touch-screen technologies and applications. It will also cover the recent developments towards achieving thinner, lightweight and cost-reduced touch screen panels in the future via integration of touch functionalities. Part 2 ''Gesture Interfaces'' will examine techniques and applications in stereoscopic 3D computer vision, structured-light 3D computer vision and time-of-flight 3D computer vision in gesture interfaces. Part 3 ''Voice Interfaces'' will revie...

  6. PXR as a mediator of herb-drug interaction.

    Science.gov (United States)

    Hogle, Brett C; Guan, Xiudong; Folan, M Maggie; Xie, Wen

    2018-04-01

    Medicinal herbs have been a part of human medicine for thousands of years. The herb-drug interaction is an extension of drug-drug interaction, in which the consumptions of herbs cause alterations in the metabolism of drugs the patients happen to take at the same time. The pregnane X receptor (PXR) has been established as one of the most important transcriptional factors that regulate the expression of phase I enzymes, phase II enzymes, and drug transporters in the xenobiotic responses. Since its initial discovery, PXR has been implicated in multiple herb-drug interactions that can lead to alterations of the drug's pharmacokinetic properties and cause fluctuating therapeutic efficacies, possibly leading to complications. Regions of the world that heavily incorporate herbalism into their primary health care and people turning to alternative medicines as a personal choice could be at risk for adverse reactions or unintended results from these interactions. This article is intended to highlight our understanding of the PXR-mediated herb-drug interactions. Copyright © 2017. Published by Elsevier B.V.

  7. Base technology development enhances state-of-the-art in meeting performance requirements

    International Nuclear Information System (INIS)

    Freedman, J.M.; Allen, G.C. Jr.; Luna, R.E.

    1987-01-01

    Sandia National Laboratories (SNL) has responsibility to the United States Department of Energy (DOE) for baseline technology to support the design of radioactive material transportation packages. To fulfill this responsibility, SNL works with industry, government agencies, and national laboratories to identify and develop state-of-the-art technology required to design and test safe, cost-effective radioactive materials packages. Principal elements of the base technology program include: 1) analysis techniques, 2) testing, 3) subsystem and component development, 4) packaging systems development support, and 5) technical support for policy development. These program elements support a systems approach for meeting performance requirements and assure that there is a sound underlying technical basis for both transportation packaging design and associated policy decisions. Highlights from the base technology program included in this paper are testing, design and analysis methods, advanced materials, risk assessment and logistics models, and transportation package support

  8. The state of the art of wind energy conversion systems and technologies: A review

    International Nuclear Information System (INIS)

    Cheng, Ming; Zhu, Ying

    2014-01-01

    Highlights: • This paper reviews the state of the art of wind energy conversion systems. • Different types of common wind energy conversion systems are classified and compared. • The four most popular MPPT control methods are reviewed and compared. • The latest development of wind energy conversion technologies is introduced. • Future trends of the wind energy conversion technologies are discussed. - Abstract: This paper gives a comprehensive review of the state of the art of wind energy conversion systems (WECS) and technologies, with an emphasis on wind power generator and control. First, different types of common WECSs are classified according to their features and drive train types. The WECSs are compared on the basis of the volume, weight, cost, efficiency, system reliability and fault ride through capability. The maximum power point tracking (MPPT) control, which aims to make the generator speed meet an optimum value to ensure the maximum energy yield, plays a key role in the variable speed WECSs. A comprehensive review and comparison of the four most popular MPPT control methods are carried out and improvements for each method are presented. Furthermore, the latest development of wind energy conversion technologies is introduced, such as the brushless doubly fed induction generator (BDFIG), the stator permanent magnet synchronous generators, the magnetic-geared generators, dual power flow WECS with the electrical variable transmission (EVT) machine, and direct grid-connected WECS. Finally, the future trends of the technologies are discussed

  9. Art, Media, and Sense-making in Responsive Urban Environments

    DEFF Research Database (Denmark)

    Allingham, Peter

    2013-01-01

    The aim of the article is to elucidate experience and sense-making in interactive, responsive urban environments through analysis of aesthetic and media aspects of art in such environments. As an analytic example the sculpture D-Tower from the Dutch town of Doetinchem has been chosen. The sculptu...... in order to make hitherto invisible and private emotions and feelings visible and public.......The aim of the article is to elucidate experience and sense-making in interactive, responsive urban environments through analysis of aesthetic and media aspects of art in such environments. As an analytic example the sculpture D-Tower from the Dutch town of Doetinchem has been chosen. The sculpture...... artistic and interactive, responsive media qualities are blended, new forms of experience and sense-making are promoted. It may happen due to emergence and adaptation that may transform both the ‘experiencee’ and also the experiential environment. In this case information technology has been applied...

  10. Developing Course Materials for Technology-Mediated Chinese Language Learning

    Science.gov (United States)

    Kubler, Cornelius C.

    2018-01-01

    This article discusses principles involved in developing course materials for technology-mediated Chinese language learning, with examples from a new course designed to take into account the needs of distance and independent learners. Which learning environment is most efficient for a given learning activity needs to be carefully considered. It…

  11. Med5(Nut1) and Med17(Srb4) Are Direct Targets of Mediator Histone H4 Tail Interactions

    Science.gov (United States)

    Liu, Zhongle; Myers, Lawrence C.

    2012-01-01

    The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone tail peptides substituted with an amino acid analog that is a UV activatible crosslinker, we have identified specific subunits within Mediator that participate in histone tail interactions. Using Mediator purified from mutant yeast strains we have evaluated the impact of these subunits on histone tail binding. This analysis has identified the Med5 subunit of Mediator as a target for histone tail interactions and suggests that the previously observed effect of med5 mutations on telomeric heterochromatin and silencing is direct. PMID:22693636

  12. Techno-Organic Practices in the Nordic Art

    DEFF Research Database (Denmark)

    Beloff, Laura

    2017-01-01

    biological matter and natural environment. Roy Ascott has claimed already in 2000: ‘MOISTWARE erodes the boundary between hardware and wetware’ (Ascott 2000). Biotechnology is an engineering discipline that has, in recent decades, entered the realm of the arts. A growing number of artists utilizing...... technological and biotechnological methods are also inextricably pairing art practices with living matter. Historical antecedents for this type of art can be traced to art that deals with biological or technological matter, for example land art, art that included animals, and digital art works. The art works...

  13. Art27 interacts with GATA4, FOG2 and NKX2.5 and is a novel co-repressor of cardiac genes.

    Directory of Open Access Journals (Sweden)

    Daniel R Carter

    Full Text Available Transcription factors play a crucial role in regulation of cardiac biology. FOG-2 is indispensable in this setting, predominantly functioning through a physical interaction with GATA-4. This study aimed to identify novel co-regulators of FOG-2 to further elaborate on its inhibitory activity on GATA-4. The Art27 transcription factor was identified by a yeast-2-hybrid library screen to be a novel FOG-2 protein partner. Characterisation revealed that Art27 is co-expressed with FOG-2 and GATA-4 throughout cardiac myocyte differentiation and in multiple structures of the adult heart. Art27 physically interacts with GATA-4, FOG-2 and other cardiac transcription factors and by this means, down-regulates their activity on cardiac specific promoters α-myosin heavy chain, atrial natriuretic peptide and B-type natriuretic peptide. Regulation of endogenous cardiac genes by Art27 was shown using microarray analysis of P19CL6-Mlc2v-GFP cardiomyocytes. Together these results suggest that Art27 is a novel transcription factor that is involved in downregulation of cardiac specific genes by physically interacting and inhibiting the activity of crucial transcriptions factors involved in cardiac biology.

  14. Scientists and artists: ""Hey! You got art in my science! You got science on my art

    Energy Technology Data Exchange (ETDEWEB)

    Elfman, Mary E [Los Alamos National Laboratory; Hayes, Birchard P [Los Alamos National Laboratory; Michel, Kelly D [Los Alamos National Laboratory; Boyer, Brian D [Los Alamos National Laboratory

    2010-01-01

    The pairing of science and art has proven to be a powerful combination since the Renaissance. The combination of these two seemingly disparate disciplines ensured that even complex scientific theories could be explored and effectively communicated to both the subject matter expert and the layman. In modern times, science and art have frequently been considered disjoint, with objectives, philosophies, and perspectives often in direct opposition to each other. However, given the technological advances in computer science and high fidelity 3-D graphics development tools, this marriage of art and science is once again logically complimentary. Art, in the form of computer graphics and animation created on supercomputers, has already proven to be a powerful tool for improving scientific research and providing insight into nuclear phenomena. This paper discusses the power of pairing artists with scientists and engineers in order to pursue the possibilities of a widely accessible lightweight, interactive approach. We will use a discussion of photo-realism versus stylization to illuminate the expected beneficial outcome of such collaborations and the societal advantages gained by a non-traditional pa11nering of these two fields.

  15. Arte e tecnologia: intersecções

    Directory of Open Access Journals (Sweden)

    Paulo Bernardino

    2010-01-01

    formulations according to positioning of the author and the observer. The result of the intersection between technology and interactivity drives us to perceive the development of the idea of shared production that spreads out as will inherent to the attitude of the creative act. The work, on being revealed in the aspiration of interactivity enounces a positioning that is linked to the technological means, on space and proceedings issues. In the art studies, it is further growing the importance of a quest for a neutral, universal guide line, in order to assimilate an ideological component the reveals itself in the attitude inherent to the use of these new digital technologies. We will try to understand how is the meaning of the images coordinated, and why do we need and seek for images. To finish we will endeavor to the proceedings of the viewer before the digital innovations, in order to understand in which way the interaction affects the positioning of the subject in relation to aspectos of creativity.

  16. Indigenous Learning Preferences and Interactive Technologies

    Science.gov (United States)

    Kitchenham, Andrew

    2017-01-01

    This three-year research study examined the influence of interactive technologies on the math achievement of Indigenous students in Years 4, 5, 6 and 7 technology-equipped classrooms in a rural elementary school in British Columbia, Canada. Using a mixed-methods approach, the researcher conducted semistructured interviews and collected math…

  17. How nursing home residents with dementia respond to the interactive art installation ‘VENSTER' : a pilot study

    NARCIS (Netherlands)

    Tom Luyten; Susy Braun; Gaston Jamin; L. de Witte; Susan van Hooren

    2017-01-01

    The goal of this study was (1) to determine whether and how nursing home residents with dementia respond to the interactive art installation in general and (2) to identify whether responses change when the content type and, therefore, the nature of the interaction with the artwork changes. The

  18. Technology as Mediation Tool for Improving Teaching Profession in Higher Education Practices

    Science.gov (United States)

    Altinay-Gazi, Zehra; Altinay-Aksal, Fahriye

    2017-01-01

    Technology became a mediation tool for forming information and developing skills is teacher education programs of higher education institutions because technological tools can be used for self-reflection of prospective teachers' teaching performances. Practical implementation of teacher education programmes is a part of quality indicator in higher…

  19. Viewing Chinese art on an interactive tabletop.

    Science.gov (United States)

    Hsieh, Chun-ko; Hung, Yi-Ping; Ben-Ezra, Moshe; Hsieh, Hsin-Fang

    2013-01-01

    To protect fragile paintings and calligraphy, Taiwan's National Palace Museum (NPM) has policies controlling the frequency and duration of their exposure. So, visitors might not see the works they planned to see. To address this problem, the NPM installed an interactive tabletop for viewing the works. This tabletop, the first to feature multiresolution and gigapixel photography technology, displays extremely high-quality images revealing brushwork-level detail. A user study at the NPM examined the tabletop's performance and collected visitor feedback.

  20. Applying Multi-Touch Technology to Facilitate the Learning of Art Appreciation: From the View of Motivation and Annotation

    Science.gov (United States)

    Hung, Hui-Chun; Young, Shelley Shwu-Ching

    2017-01-01

    Handheld technologies with multi-touch functions have been embraced by the young generation and become their important tool for social and learning purposes. The purpose of this study was to explore how the state-of-art devices could be integrated into authentic art appreciation courses to motivate and enhance students' learning. It was conducted…

  1. DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

    Directory of Open Access Journals (Sweden)

    Lei Li

    Full Text Available Protein-protein interactions (PPIs are frequently mediated by the binding of a modular domain in one protein to a short, linear peptide motif in its partner. The advent of proteomic methods such as peptide and protein arrays has led to the accumulation of a wealth of interaction data for modular interaction domains. Although several computational programs have been developed to predict modular domain-mediated PPI events, they are often restricted to a given domain type. We describe DomPep, a method that can potentially be used to predict PPIs mediated by any modular domains. DomPep combines proteomic data with sequence information to achieve high accuracy and high coverage in PPI prediction. Proteomic binding data were employed to determine a simple yet novel parameter Ligand-Binding Similarity which, in turn, is used to calibrate Domain Sequence Identity and Position-Weighted-Matrix distance, two parameters that are used in constructing prediction models. Moreover, DomPep can be used to predict PPIs for both domains with experimental binding data and those without. Using the PDZ and SH2 domain families as test cases, we show that DomPep can predict PPIs with accuracies superior to existing methods. To evaluate DomPep as a discovery tool, we deployed DomPep to identify interactions mediated by three human PDZ domains. Subsequent in-solution binding assays validated the high accuracy of DomPep in predicting authentic PPIs at the proteome scale. Because DomPep makes use of only interaction data and the primary sequence of a domain, it can be readily expanded to include other types of modular domains.

  2. Trait-mediated trophic interactions: is foraging theory keeping up?

    Science.gov (United States)

    Steven F. Railsback; Bret C. Harvey

    2013-01-01

    Many ecologists believe that there is a lack of foraging theory that works in community contexts, for populations of unique individuals each making trade-offs between food and risk that are subject to feedbacks from behavior of others. Such theory is necessary to reproduce the trait-mediated trophic interactions now recognized as widespread and strong. Game theory can...

  3. Computer-mediated interdisciplinary teams: theory and reality.

    Science.gov (United States)

    Vroman, Kerryellen; Kovacich, Joann

    2002-05-01

    The benefit of experience, tempered with the wisdom of hindsight and 5 years of text-based, asynchronous, computer-mediated, interdisciplinary team communications, provides the energy, insights and data shared in this article. Through the theoretical lens of group dynamics and the epistemology of interdisciplinary teaming, we analyze the interactions of a virtual interdisciplinary team to provide an understanding and appreciation of collaborative interdisciplinary communication in the context of interactive technologies. Whilst interactive technologies may require new patterns of language similar to that of learning a foreign language, what is communicated in the interdisciplinary team process does not change. Most important is the recognition that virtual teams, similar to their face-to-face counterparts, undergo the same challenges of interdisciplinary teaming and group developmental processes of formation: forming, storming, norming, performing, and transforming. After examining these dynamics of communication and collaboration in the context of the virtual team, the article concludes with guidelines facilitating interdisciplinary team computer-mediated communication.

  4. Mediated Effects of Technology Competencies and Experiences on Relations among Attitudes Towards Technology Use, Technology Ownership, and Self Efficacy about Technological Pedagogical Content Knowledge

    Science.gov (United States)

    Yerdelen-Damar, Sevda; Boz, Yezdan; Aydın-Günbatar, Sevgi

    2017-08-01

    This study examined the relations of preservice science teachers' attitudes towards technology use, technology ownership, technology competencies, and experiences to their self-efficacy beliefs about technological pedagogical content knowledge (TPACK). The present study also investigated interrelations among preservice teachers' attitudes towards technology use, technology ownership, technology competencies, and experiences. The participants of study were 665 elementary preservice science teachers (467 females, 198 males) from 7 colleges in Turkey. The proposed model based on educational technology literature was tested using structural equation modeling. The model testing results revealed that preservice teachers' technology competencies and experiences mediated the relation of technology ownership to their TPACK self efficacy beliefs. The direct relation of their possession of technology to their TPACK self efficacy beliefs was insignificant while the indirect relation through their technology competencies and experiences was significant. The results also indicated there were significant direct effects of preservice teachers' attitudes towards technology use, technology competencies, and experiences on their TPACK self efficacy beliefs.

  5. Light and dark an exploration in science, nature, art and technology

    CERN Document Server

    Greene, David

    2002-01-01

    An entertaining, instructive, diverse, and unusual book, Light and Dark: An Exploration in Science, Nature, Art and Technology encompasses a wide range of topics not normally found in one book.With more than 100 diagrams, graphs, and figures, the subjects discussed include the history of artificial lighting, eclipse cycles, light-sensitive eyeglasses, rainbows, art, bioluminescence, the clock setting at the South Pole, zebra stripe patterns, lighthouses, color perception, the harvest moon, and how information and speech can be conveyed by light from the sun or a laser.The book encourages readers to take a more careful look at many familiar phenomena, such as the variations in the duration of twilight through the year and the ability of human vision to misinterpret patterns of lines under certain conditions. It describes the anatomical peculiarities of four-eyed fish and explains how the Jewish calendar contrives to follow both solar and lunar cycles. It also presents the reasons why tortoise shell cats are al...

  6. Graphical User Interface in Art

    Science.gov (United States)

    Gwilt, Ian

    This essay discusses the use of the Graphical User Interface (GUI) as a site of creative practice. By creatively repositioning the GUI as a work of art it is possible to challenge our understanding and expectations of the conventional computer interface wherein the icons and navigational architecture of the GUI no longer function as a technological tool. These artistic recontextualizations are often used to question our engagement with technology and to highlight the pivotal place that the domestic computer has taken in our everyday social, cultural and (increasingly), creative domains. Through these works the media specificity of the screen-based GUI can broken by dramatic changes in scale, form and configuration. This can be seen through the work of new media artists who have re-imagined the GUI in a number of creative forms both, within the digital, as image, animation, net and interactive art, and in the analogue, as print, painting, sculpture, installation and performative event. Furthermore as a creative work, the GUI can also be utilized as a visual way-finder to explore the relationship between the dynamic potentials of the digital and the concretized qualities of the material artifact.

  7. Negative Interpersonal Interactions and Dating Abuse Perpetration: The Mediating Role of Dispositional Forgivingness.

    Science.gov (United States)

    Garthe, Rachel C; Griffin, Brandon J; Worthington, Everett L; Goncy, Elizabeth A; Sullivan, Terri N; Coleman, Jennifer A; Davis, Don E; Kwakye-Nuako, Charlotte O; Mokushane, Thapelo; Makola, Solomon; Anakwah, Nkansah

    2017-06-01

    Theory and research suggest that an individual's negative interactions with his or her parents or romantic partner are associated with the perpetration of dating abuse. Research is beginning to explore the role of forgivingness within abusive romantic relationships, and these preliminary findings suggest that dispositional forgivingness might mediate the relations between negative interpersonal interactions and dating abuse. The current study assessed negative interactions with one's parents and one's romantic partner, the frequency of dating abuse perpetration, and dispositional forgivingness of others and oneself among a sample of emerging adults in college ( n = 421). Dispositional forgivingness of others was negatively associated with the perpetration of emotional/verbal dating abuse and threatening behaviors, and it mediated relations between negative interpersonal interactions and dating abuse perpetration. Our findings suggest that the tendency to forgive others may explain why some individuals who experience negative interpersonal interactions with parents or romantic partners do not escalate to perpetration of abuse within their romantic relationships. Implications for future research and application are discussed.

  8. Lifelong Learning in Artistic Context Mediated by Advanced Technologies

    Science.gov (United States)

    Ferrari, Mirella

    2016-01-01

    This research starts by analysing the current state of artistic heritage in Italy and studying some examples in Europe: we try to investigate the scope of non-formal learning in artistic context, mediated by advanced technology. The framework within which we have placed our investigation is that of lifelong learning and lifedeep learning. The…

  9. Asymptotically approaching the past: historiography and critical use of sources in art technological source research

    NARCIS (Netherlands)

    Clarke, M.; Kroustallis, S.; Townsend, J.H.; Cenalmor Bruquetas, E.; Stijnman, A.; San Andres Moya, M.

    2008-01-01

    This paper proposes that historiographic methods should be applied during art technological source research. Sources cannot always be used uncritically as being simply reliable records of contemporary workshop practice. The accuracy, date and origin of the technical information embedded within

  10. Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

    DEFF Research Database (Denmark)

    Zhu, Xuefeng; Wirén, Marianna; Sinha, Indranil

    2006-01-01

    Mediator exists in a free form containing the Med12, Med13, CDK8, and CycC subunits (the Srb8-11 module) and a smaller form, which lacks these four subunits and associates with RNA polymerase II (Pol II), forming a holoenzyme. We use chromatin immunoprecipitation (ChIP) and DNA microarrays...... to investigate genome-wide localization of Mediator and the Srb8-11 module in fission yeast. Mediator and the Srb8-11 module display similar binding patterns, and interactions with promoters and upstream activating sequences correlate with increased transcription activity. Unexpectedly, Mediator also interacts...... with the downstream coding region of many genes. These interactions display a negative bias for positions closer to the 5' ends of open reading frames (ORFs) and appear functionally important, because downregulation of transcription in a temperature-sensitive med17 mutant strain correlates with increased Mediator...

  11. A-State-of-the-Art Report on Application of Radiation Technology to Environmental Pollution Control

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Kwang; Lee, Myun Joo

    2004-06-15

    Radiation technology has been rapidly developed for decades and its applicability also enlarged to many fields such as environmental protection, medical care, manufacturing industry, agriculture, and bio technology. In this report, we focused on the present situation of the development of radiation facilities and state-of-the-art on application of radiation to environmental pollution control including purification of flue gas, waste water treatment, and recycling of biological waste. We especially discussed the radiation technology for environmental pollution control and described the capability of its application to the industrial plants in Korea.

  12. Med5(Nut1 and Med17(Srb4 are direct targets of mediator histone H4 tail interactions.

    Directory of Open Access Journals (Sweden)

    Zhongle Liu

    Full Text Available The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone tail peptides substituted with an amino acid analog that is a UV activatible crosslinker, we have identified specific subunits within Mediator that participate in histone tail interactions. Using Mediator purified from mutant yeast strains we have evaluated the impact of these subunits on histone tail binding. This analysis has identified the Med5 subunit of Mediator as a target for histone tail interactions and suggests that the previously observed effect of med5 mutations on telomeric heterochromatin and silencing is direct.

  13. From art to applied science.

    Science.gov (United States)

    Schatzberg, Eric

    2012-09-01

    Before "applied science" and "technology" became keywords, the concept of art was central to discourse about material culture and its connections to natural knowledge. By the late nineteenth century, a new discourse of applied science had replaced the older discourse of art. This older discourse of art, especially as presented in Enlightenment encyclopedias, addressed the relationship between art and science in depth. But during the nineteenth century the concept of fine art gradually displaced the broader meanings of "art," thus undermining the utility of the term for discourse on the relationship between knowledge and practice. This narrowed meaning of "art" obscured key aspects of the industrial world. In effect, middle-class agents of industrialism, including "men of science," used the rhetoric of "applied science" and, later, "technology" to cement the exclusion of artisanal knowledge from the discourse of industrial modernity.

  14. Experiential Avoidance as a Mediator between Rejection Sensitivity and Social Interaction Anxiety

    Directory of Open Access Journals (Sweden)

    Marcella L. Sintos

    2017-12-01

    Full Text Available Due to the overarching and related concepts involved in interpersonal sensitivity, this study aimed to look at the differences between, and relationships of, some of its concepts by explaining the mediating effect of experiential avoidance on rejection sensitivity and social interaction anxiety. One hundred fifty-nine undergraduates within the National Capital Region, aged 16 to 40 (M = 19.29, SD = 2.89, and comprising 89 females and 70 males participated in the study. Results show that both rejection sensitivity and experiential avoidance significantly affect social interaction anxiety. Also, a full mediation occurs when experiential avoidance serves as a mediator. This is explained through the occurrence of habitual coping, whereby the cognitive aspect of behavior (in this case, rejection sensitivity becomes dormant and unnecessary. Some variables which may have possibly accounted for the relationship between these concepts may be considered for future research to validate and better understand the findings of this study.

  15. A State-of-the-Art Report on Technologies of a Safety Assessment and a Radioactivity Exposure Assessment for the Decommissioning Process of Nuclear Facilities

    International Nuclear Information System (INIS)

    Jeong, Kwan Seong; Kang, Young Ae; Lee, Dong Gyu; Lee, Kune Woo; Jung, Chong Hun

    2007-09-01

    This report is to provide the reference contents of research and development for technologies of radioactivity exposure and safety assessment for development of the decommissioning technology for nuclear facilities. This report consists of as follows: - Analyzing and discussing on state-of-the-art technologies of a radioactivity exposure assessment of a decommissioning for nuclear facilities - Analyzing and discussing on state-of-the-art technologies of a safety assessment of a decommissioning for nuclear facilities

  16. A State-of-the-Art Report on Technologies of a Safety Assessment and a Radioactivity Exposure Assessment for the Decommissioning Process of Nuclear Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Kwan Seong; Kang, Young Ae; Lee, Dong Gyu; Lee, Kune Woo; Jung, Chong Hun

    2007-09-15

    This report is to provide the reference contents of research and development for technologies of radioactivity exposure and safety assessment for development of the decommissioning technology for nuclear facilities. This report consists of as follows: - Analyzing and discussing on state-of-the-art technologies of a radioactivity exposure assessment of a decommissioning for nuclear facilities - Analyzing and discussing on state-of-the-art technologies of a safety assessment of a decommissioning for nuclear facilities.

  17. The K Domain Mediates Homologous and Heterologous Interactions Between FLC and SVP Proteins of Brassica juncea

    Directory of Open Access Journals (Sweden)

    Ma Guanpeng

    2015-07-01

    Full Text Available The transcription factors FLOWERING LOCUS C (FLC and SHORT VEGETATIVE PHASE (SVP can interact to form homologous and heterologous protein complexes that regulate flowering time in Brassica juncea Coss. (Mustard.Previous studies showed that protein interactions were mediated by the K domain, which contains the subdomains K1, K2 and K3. However, it remains unknown how the subdomains mediate the interactions between FLC and SVP. In the present study, we constructed several mutants of subdomains K1–K3 and investigated the mechanisms involved in the heterologous interaction of BjFLC/BjSVP and in the homologous interaction of BjFLC/BjFLC or BjSVP/BjSVP. Yeast two-hybrid and β-Galactosidase activity assays showed that the 19 amino acids of the K1 subdomain in BjSVP and the 17 amino acids of the K1 subdomain in BjFLC were functional subdomains that interact with each other to mediate hetero-dimerization. The heterologous interaction was enhanced by the K2 subdomain of BjSVP protein, but weakened by its interhelical domain L2. The heterologous interaction was also enhanced by the K2 subdomain of BjFLC protein, but weakened by its K3 subdomain. The homologous interaction of BjSVP was mediated by the full K-domain. However, the homologous interaction of BjFLC was regulated only by its K1 and weakened by its K2 and K3 subdomains. The results provided new insights into the interactions between FLC and SVP, which will be valuable for further studies on the molecular regulation mechanisms of the regulation of flowering time in B. juncea and other Brassicaceae.

  18. New Global Art Connection: Paying Tribute to the Wave-Makers (1910-2010)

    Science.gov (United States)

    Kan, Koon Hwee

    2013-01-01

    This paper highlights "Wave-Makers (1910--2010)", a collaborative timeline redesign project, which involves interactive and advanced web-based technology to connect and complement arts curricula at two higher education institutions, one located in China and another in the United States. Through in-depth research, video-conferencing,…

  19. Presence in Video-Mediated Interactions: Case Studies at CSIRO

    Science.gov (United States)

    Alem, Leila

    Although telepresence and a sense of connectedness with others are frequently mentioned in media space studies, as far as we know, none of these studies report attempts at assessing this critical aspect of user experience. While some attempts have been made to measure presence in virtual reality or augmented reality, (a comprehensive review of existing measures is available in Baren and Ijsselsteijn [2004]), very little work has been reported in measuring presence in video-mediated collaboration systems. Traditional studies of video-mediated collaboration have mostly focused their evaluation on measures of task performance and user satisfaction. Videoconferencing systems can be seen as a type of media space; they rely on technologies of audio, video, and computing put together to create an environment extending the embodied mind. This chapter reports on a set of video-mediated collaboration studies conducted at CSIRO in which different aspects of presence are being investigated. The first study reports the sense of physical presence a specialist doctor experiences when engaged in a remote consultation of a patient using the virtual critical care unit (Alem et al., 2006). The Viccu system is an “always-on” system connecting two hospitals (Li et al., 2006). The presence measure focuses on the extent to which users of videoconferencing systems feel physically present in the remote location. The second study reports the sense of social presence users experience when playing a game of charades with remote partners using a video conference link (Kougianous et al., 2006). In this study the presence measure focuses on the extent to which users feel connected with their remote partners. The third study reports the sense of copresence users experience when building collaboratively a piece of Lego toy (Melo and Alem, 2007). The sense of copresence is the extent to which users feel present with their remote partner. In this final study the sense of copresence is

  20. Drawing a Transductive Ecosophy in Process: Technological Arts, Residual Matter, Associated Milieus

    Directory of Open Access Journals (Sweden)

    Gisèle Trudel

    2015-06-01

    Full Text Available Drawing a Transductive Ecosophy in Process: Technological Arts, Residual Matter, Associated Milieus by Gisèle Trudel. NANO: New American Notes Online, Issue 7: The Aesthetics of Trash - nanocrit.com. This text examines the tetralogy of media artworks about residual matter produced by Ælab between 2008 and 2014. Taking its own title as a diagram (Deleuze and Guattari Mille Plateaux, it charts and builds on the processes of these artworks, elucidating their relations to materiality, philosophy and technicity. Technological research-creation becomes in these instances a transdisciplinary aesthetic act, emerging from an ecology of practices that combine humans, non-humans and waste matter in an effort to increase attentiveness in actions.

  1. Neutrons and art

    International Nuclear Information System (INIS)

    Panczyk, E.; Walis, L.

    2004-01-01

    Following modern trends in art objects connoisseurship, through examination of the structure of art objects supports traditional studies conducted by art historians based on composition, iconographic and stylistic comparisons. It must be emphasized that complete technological examinations are carried out by means of comprehensive physical and chemical studies. Among various methods used for the examination of art objects, methods which apply neutrons such as instrumental neutron activation analysis (INAA), prompt gamma activation analysis (PGAA) and neutron-induced autoradiography are crucial due to their high sensitivity, reproducibility and capability of simultaneous determination of several tens of elements. Systematic studies on art objects using instrumental neutron activation analysis and neutron autoradiography have been carried out in the institute of Nuclear Chemistry and Technology. It was possible to accumulate a number of essential data on the concentration of trace elements particularly in chalk grounds and pigments (such as lead white, lead-tin yellow, smalt), Chinese porcelain, Thai ceramics, silver denarius, jewellery made of copper alloys, as well as in the clay fillings of Egyptian mummies. The above mentioned examination of art objects prior to their conservation helps to determine precisely the materials used in the process of creating art objects, as well as to identify the appropriate place of origin of particular materials. (author)

  2. Theoretical Propositions for the Citizen Formation Mediated by Technology

    Directory of Open Access Journals (Sweden)

    Tania Margarita Martínez de Padrón

    2018-02-01

    Full Text Available The research presented emerges from the connotations concerning the formation of the citizenship by the information technology and communication. Be part of the conception of the current citizen and the influence that has emerged through the utility of the various social networks, as well as Canaima education project and the guidance provided to schoolchildren in this sense. The general objective was to generate propositions theoretical that guide the formation of citizenship mediated by ICT in the primary schools of Santa Teresa del Tuy. The methodology used was the qualitative paradigm, based on the interpretative phenomenological approach of Heidegger, which is interested in discovering and understanding the meanings, habits and practices of the human being. Castle (2000: 5. The researcher approached the field object of study to observe, describe and interpret a reality. As an instrument used the interview in depth. The information obtained was recorded in pictures which allowed to comply with the development of specific objectives through triangulation. On whose findings prevailed deviating from the use of technological tools and how these have formed the formation of citizenship in school children in their behavior and actions. At the same time, allowed know from educational technological approach, that sparing the teacher provides guidance that redirect the formation of citizenship. Also was the stated objective as it was the theoretical propositions that guide the formation of citizens ICT-mediated.

  3. Metamorphosing art: multimedia spectacles as new forms of art and education

    OpenAIRE

    Santana, Helena; Santana, Rosário

    2004-01-01

    The interaction of different domains of knowledge and art, namely music, theatre, design, mathematics, physics… contributes to organise a musical performance that has an original form and develops new forms of education. Using different art forms – BACH2CAGE - is an original spectacle who confluences different domains of knowledge, communication and art. “More than a performance, Bach2Cage is a process, an experimental laboratory in crossing music/performing arts with multimedia/digital ...

  4. Explanation in causal inference methods for mediation and interaction

    CERN Document Server

    VanderWeele, Tyler

    2015-01-01

    A comprehensive examination of methods for mediation and interaction, VanderWeele's book is the first to approach this topic from the perspective of causal inference. Numerous software tools are provided, and the text is both accessible and easy to read, with examples drawn from diverse fields. The result is an essential reference for anyone conducting empirical research in the biomedical or social sciences.

  5. Best-practice model for technology enhanced learning in the creative arts

    Directory of Open Access Journals (Sweden)

    Jess Power

    2016-12-01

    Full Text Available This paper presents a best-practice model for the redesign of virtual learning environments (VLEs within creative arts to augment blended learning. In considering a blended learning best-practice model, three factors should be considered: the conscious and active human intervention, good learning design and pedagogical input, and the sensitive handling of the process by trained professionals. This study is based on a comprehensive VLE content analysis conducted across two academic schools within the creative arts at one Post-92 higher education (HE institution. It was found that four main barriers affect the use of the VLE within creative arts: lack of flexibility in relation to navigation and interface, time in developing resources, competency level of tutors (confidence in developing online resources balanced against other flexible open resources and factors affecting the engagement of ‘digital residents’. The experimental approach adopted in this study involved a partnership between the learning technology advisor and academic staff, which resulted in a VLE best-practice model that focused directly on improving aesthetics and navigation. The approach adopted in this study allowed a purposive sample of academic staff to engage as participants, stepping back cognitively from their routine practices in relation to their use of the VLE and questioning approaches to how they embed the VLE to support teaching and learning. The model presented in this paper identified a potential solution to overcome the challenges of integrating the VLE within creative arts. The findings of this study demonstrate positive impact on staff and student experience and provide a sustainable model of good practice for the redesign of the VLE within creative disciplines.

  6. Human-technology interaction for standoff IED detection

    Science.gov (United States)

    Zhang, Evan; Zou, Yiyang; Zachrich, Liping; Fulton, Jack

    2011-03-01

    IEDs kill our soldiers and innocent people every day. Lessons learned from Iraq and Afghanistan clearly indicated that IEDs cannot be detected/defeated by technology alone; human-technology interaction must be engaged. In most cases, eye is the best detector, brain is the best computer, and technologies are tools, they must be used by human being properly then can achieve full functionality. In this paper, a UV Raman/fluorescence, CCD and LWIR 3 sensor fusion system for standoff IED detection and a handheld fusion system for close range IED detection are developed and demonstrated. We must train solders using their eyes or CCD/LWIR cameras to do wide area search while on the move to find small suspected area first then use the spectrometer because the laser spot is too small, to scan a one-mile long and 2-meter wide road needs 185 days although our fusion system can detect the IED in 30m with 1s interrogating time. Even if the small suspected area (e.g., 0.5mx0.5m) is found, human eyes still cannot detect the IED, soldiers must use or interact with the technology - laser based spectrometer to scan the area then they are able to detect and identify the IED in 10 minutes not 185 days. Therefore, the human-technology interaction approach will be the best solution for IED detection.

  7. Anger in women treated with assisted reproductive technology (ART): effects on mother and newborn.

    Science.gov (United States)

    Muscatello, Maria Rosaria Anna; Lorusso, Simona; Bruno, Antonio; Reale, Rosa; Ciura, Giulia La; Laganà, Antonio Simone; Retto, Giovanni; Sturlese, Emanuele; Zoccali, Rocco Antonio

    2016-03-01

    To assess anger, as well as other negative emotions, in women who underwent assisted reproductive technology (ART) respect to women who conceived naturally, and explore the effect of anger on neonatal outcomes. We recorded personal and obstetric history of the patients, neonatal weight, Apgar score, obstetric and neonatal complications. We performed Structural Clinical Interview for DSM-SCID I and II in order to assess the DSM IV axis I and axis II, State-Trait Anger Expression Inventory 2 (STAXI-2), the Self-rating Depression Scale (SDS) and Self-rating Anxiety scale (SAS). On the STAXI-2 scale, the ART group scored higher than the natural conception group on measures of general tendency and personality disposition to get angry. Moreover, the ART group women showed quite low levels of tolerance to negative environmental feedback. Our results further suggest that trait anger provides the most meaningful contribution as predictor of weight at birth. No significant differences were found for anxiety and depression between the two groups. Our study highlights the important role of anger during pregnancy, and suggests the need for further studies on both biochemical and behavioural patterns in larger samples of women who became pregnant by ART.

  8. Music Technology-Mediated Teaching and Learning Approach for Music Education: A Case Study from an Elementary School in South Korea

    Science.gov (United States)

    Kim, Eunjin

    2013-01-01

    This study aims to show how music technology mediated (or music software mediated) music teaching and learning can provide an effective pedagogy in music education. It also seeks to demonstrate that music technology mediated teaching is in accordance with socio-educational trends for both postmodern values and IT mediated learning. The new…

  9. Investigations of interactions mediated by neutral currents

    International Nuclear Information System (INIS)

    Witek, M.

    2007-03-01

    The report is devoted to four-fermion interactions mediated by the neutral currents. The results from the second phase of LEP are presented, when the production of two massive bosons was possible with the increased energy of the e + e - collisions. It enabled for a direct test of nonabelian structure of the electroweak theory. The results concern the four-fermion production of the pairs of the ZZ bosons, single Z and Zγ * production as well as search for anomalous gauge bosons couplings. The large part of the report is devoted to experimental techniques, physics analyses and discussion of results. (author)

  10. Arquitectura, arte funcional

    Directory of Open Access Journals (Sweden)

    Monjo Carrió, Juan

    1985-10-01

    Full Text Available The begining of this work is devoted to the analysis of the concepts of Art, Science and Technique and their historical evolution, distinguishing between "fine arts" and "technique arts". Following, Architect and Architecture terms are defined both conceptual and professionally, analysing as well its historical evolution and pointing out the interdependence between the architectural conception as "fine art" and the constructive technology as "technique art", finally reminding the necessary scientific base of this one (Construction Physics. Consequently, the need for architecture professionals of constructive technology knowledge, is also reminded. At last, the functional character of the Architecture (Architecture as a "functional art" is analysed, going over the three basic aspects of this functionality (Integrity-firmitas, Habitability-utilitas and Aesthetics-venustas.Se inicia el trabajo analizando los conceptos de Arte, Ciencia y Técnica y su evolución histórica, distinguiendo entre ¡as "bellas artes" y las "artes técnicas". A continuación se definen los conceptos de Arquitecto y Arquitectura, tanto conceptual como profesionalmente, analizando, asimismo, su evolución histórica y haciendo hincapié en la interdependencia entre la concepción arquitectónica como "bella arte" y la tecnología constructiva como "arte técnica", para terminar recordando la necesaria base científica de esta última (la Física de la Construcción. Como consecuencia, se recuerda la necesidad de los conocimientos de la tecnología constructiva en los arquitectos profesionales. Por último, se analiza el carácter funcional de la Arquitectura (Arquitectura como "arte funcional" y se hace un breve recorrido por los tres aspectos básicos de esa funcionalidad (Integridad-firmitas, Habitabilidad-utilitas y Estética-venustas.

  11. Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems.

    Science.gov (United States)

    Kumar, Santosh; Rao, P S S; Earla, Ravindra; Kumar, Anil

    2015-03-01

    Substance abuse is a common problem among HIV-infected individuals. Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs have been identified as major reasons for non-adherence to antiretroviral therapy (ART) among HIV patients. The literature also suggests a decrease in the response to ART among HIV patients who use these substances, leading to failure to achieve optimal virological response and increased disease progression. This review discusses the challenges with adherence to ART as well as observed drug interactions and known toxicities with major drugs of abuse, such as alcohol, smoking, methamphetamine, cocaine, marijuana, and opioids. The lack of adherence and drug interactions potentially lead to decreased efficacy of ART drugs and increased ART, and drugs of abuse-mediated toxicity. As CYP is the common pathway in metabolizing both ART and drugs of abuse, we discuss the possible involvement of CYP pathways in such drug interactions. We acknowledge that further studies focusing on common metabolic pathways involving CYP and advance research in this area would help to potentially develop novel/alternate interventions and drug dose/regimen adjustments to improve medication outcomes in HIV patients who consume drugs of abuse.

  12. Socially Interactive and Passive Technologies Enhance Friendship Quality: An Investigation of the Mediating Roles of Online and Offline Self-Disclosure.

    Science.gov (United States)

    Desjarlais, Malinda; Joseph, Jessica J

    2017-05-01

    Previous studies indicate that characteristics of social-based technologies (STs) stimulate the sharing of intimate information online, which in turn enhances the quality of friendships. In addition, intimate online self-disclosure has been positively associated with offline self-disclosure. One objective of the current study was to combine the literature and test a model which postulates that STs use stimulates online self-disclosure which facilitates offline self-disclosure and, thereby, enhances the quality of close friendships. A second objective of this study was to examine if the aforementioned model applies to two categories of STs, including socially interactive technologies (SITs; e.g., instant messaging) and socially passive technologies (SPTs; e.g., reading posts on social networking sites). An online survey was conducted with 212 young adults between 18 and 25 years of age. The proposed indirect positive effects of SITs and SPTs use on the quality of friendships were supported. The positive effect of SITs use on the quality of friendships was explained entirely by the young adults' disclosure of personal information when using SITs which facilitated intimate self-disclosure during face-to-face interactions. Although there was not a direct effect of SPTs use on the quality of friendships, SPTs use was positively related to SPTs self-disclosure, which had a positive effect on offline self-disclosure. The current study enhances our understanding regarding the positive effects associated with the use of STs among close friends and identifies the contribution of online self-disclosure for offline interactions.

  13. Technology and Teacher-Student Interactions: A Review of Empirical Research

    Science.gov (United States)

    Harper, Ben

    2018-01-01

    As technology becomes ubiquitous in education, it is critical to understand the ways in which technology influences interactions between teachers and their students. The overarching research question that guided this systematic review was: What does research tell us about how technology influences interactions between teachers and students in K-12…

  14. The Role of Artefacts in Presence Mediation

    NARCIS (Netherlands)

    Vyas, Dhaval; Tzovaras, D

    2007-01-01

    Approaches to support computer mediated communication (CMC) have predominantly relied on the face-to-face communication paradigm. However, interaction and coordination can also be supported by different technological artefacts. In fact, most researches [1, 2, 3] related to ethnomethodology have

  15. Multimedia database retrieval technology and applications

    CERN Document Server

    Muneesawang, Paisarn; Guan, Ling

    2014-01-01

    This book explores multimedia applications that emerged from computer vision and machine learning technologies. These state-of-the-art applications include MPEG-7, interactive multimedia retrieval, multimodal fusion, annotation, and database re-ranking. The application-oriented approach maximizes reader understanding of this complex field. Established researchers explain the latest developments in multimedia database technology and offer a glimpse of future technologies. The authors emphasize the crucial role of innovation, inspiring users to develop new applications in multimedia technologies

  16. The best I can be: how self-accountability impacts product choice in technology mediated environments

    OpenAIRE

    Rowe, Zoe O.; Wilson, Hugh; Dimitriu, Radu; Breiter, Katja; Charnley, Fiona

    2017-01-01

    Technology-mediated environments are important not only as the location for an increasing proportion of purchases, but also as an even more pervasive part of the purchase journey. While most research into online consumer behavior focuses on attitudes as an antecedent of product choice, this article focuses on an important but hardly explored variable that may be impacted by technology-mediated environments: self-accountability. Laboratory experiments suggest that self-accountability may influ...

  17. The teacher acting as mediator in new technologies use: a case study in physics teaching

    OpenAIRE

    Almeida Valiati, Eliane Regina de; Heineck, Renato

    2005-01-01

    Nowadays, the new technologies challenge the educational practices. When teachers face this new teaching and learning pattern they need to adopt a different attitude: of a mediator, in which one its main role is to experience and mediate processes of learning construction proportioned and encouraged by the increasing inclusion of New Communication and Information Technologies (NCTIs) at schools. This paper presents the results obtained in a research which objective was to evaluate the use of ...

  18. Bluetooth as a Playful Public Art Interface

    Science.gov (United States)

    Stukoff, Maria N.

    This chapter investigates how the application of emergent communication technologies assisted in the design of playful art experience in a public place. Every Passing Moment (EPM), was a mobile public artwork that tracked and recorded any discoverable Bluetooth device to automatically seed a flower in a virtual garden projected onto an urban screen. The EPM was the first public art work to run blu_box, a custom-designed Bluetooth system for mobile telephony. The aim of blu_box was to build a system that supported playful interactions between the public and an urban screen, openly accessible to anyone with a Bluetooth-enabled mobile phone. This participatory engagement was observed in EPM on three levels, namely; unconscious, conscious, and dynamic play. Furthermore, this chapter highlights how sound and face-to-face communication proved imperative in the play dynamics of EPM. In conclusion, this chapter proposes ways in which the use of emergent communication technologies in public places, especially when interfaced with urban screening platforms, can construct playful city spaces for the public at large.

  19. VIRTUAL HERITAGE ARCHIVES: BUILDING A CENTRALIZED AUSTRALIAN ROCK ART ARCHIVE

    Directory of Open Access Journals (Sweden)

    R. A. Haubt

    2013-07-01

    Full Text Available This paper examines use of multi-media in the curation, presentation and promotion of rock art. It discusses the construction of a centralised Australian rock art database and explores new technologies available for looking at rock art. In 2011, Prof. Taçon Chair in Rock Art Research and Director of PERAHU (Place, Evolution and Rock Art Heritage Unit called for a national rock art database raising awareness of the importance of preserving rock art as part of Australia's valuable Indigenous heritage (Taçon, 2011. Australia has over 100,000 rock art sites, important heritage places for Indigenous and non-Indigenous Australians and a testament to over 10,000 years of human activity, including interactions with other peoples and the environment. Many of these sites have not been documented or recorded and are threatened by natural and cultural agents. It is becoming increasingly important to develop conservation models for the protection and preservation of sites. Indigenous cultural heritage is difficult to manage on a local government level due to complex human / time / environment relationships and the importance of intangible cultural heritage (SoE SEWPAC, 2011. Currently no centralised database system exists in Australia to curate, present and promote rock art.

  20. Is art a

    Directory of Open Access Journals (Sweden)

    Fabienne Crettaz von Roten

    2007-09-01

    Full Text Available This paper relates to a special case of science-society mediation set up during the Science et Cité festival 2005. This national event took place in about twenty cities in Switzerland to promote a closer cooperation between science and society via art (theatre, music, dance, exhibitions, cinema, etc., in order to reach the population at large. Results on the profile of the public, the role played by the cultural institutions involved, the motives of the visitors and the role of art in the science-society dialogue show that the goals aimed at by the festival's organisers were only partially reached. Moreover, the analyses shed light on the complex relation between art, science and society in public understanding of science activities.

  1. Hedonic Benefits of Close and Distant Interaction Partners: The Mediating Roles of Social Approval and Authenticity.

    Science.gov (United States)

    Venaglia, Rachel B; Lemay, Edward P

    2017-09-01

    The current research utilized ecological momentary assessment methodology to examine affective responses to interacting with close versus distant interaction partners during naturally occurring social interactions, and to test predictions regarding the mediating roles of perceived social approval and authenticity. Analysis of 4,602 social interactions reported by 176 participants suggested that, relative to interactions with distant partners, interactions with close partners were characterized by more positive affect. This effect was mediated by perceived social approval and authenticity. These findings suggest that social interactions with close others confer greater hedonic benefits relative to interactions with distant partners due to greater confidence in social approval and feelings of authenticity. Exploratory analyses suggested that interactions with close partners featured warmer and less shy behavior, and that participants who placed more importance on close relationships (as measured by high relational-interdependent self-construal) experienced more approval and authenticity in their interactions, particularly with distant partners.

  2. Interplay between cooperation-enhancing mechanisms in evolutionary games with tag-mediated interactions

    Science.gov (United States)

    Hadzibeganovic, Tarik; Stauffer, Dietrich; Han, Xiao-Pu

    2018-04-01

    Cooperation is fundamental for the long-term survival of biological, social, and technological networks. Previously, mechanisms for the enhancement of cooperation, such as network reciprocity, have largely been studied in isolation and with often inconclusive findings. Here, we present an evolutionary, multiagent-based, and spatially explicit computer model to specifically address the interactive interplay between such mechanisms. We systematically investigate the effects of phenotypic diversity, network structure, and rewards on cooperative behavior emerging in a population of reproducing artificial decision makers playing tag-mediated evolutionary games. Cooperative interactions are rewarded such that both the benefits of recipients and costs of donators are affected by the reward size. The reward size is determined by the number of cooperative acts occurring within a given reward time frame. Our computational experiments reveal that small reward frames promote unconditional cooperation in populations with both low and high diversity, whereas large reward frames lead to cycles of conditional and unconditional strategies at high but not at low diversity. Moreover, an interaction between rewards and spatial structure shows that relative to small reward frames, there is a strong difference between the frequency of conditional cooperators populating rewired versus non-rewired networks when the reward frame is large. Notably, in a less diverse population, the total number of defections is comparable across different network topologies, whereas in more diverse environments defections become more frequent in a regularly structured than in a rewired, small-world network of contacts. Acknowledging the importance of such interaction effects in social dilemmas will have inevitable consequences for the future design of cooperation-enhancing protocols in large-scale, distributed, and decentralized systems such as peer-to-peer networks.

  3. Mechanisms and ecological implications of plant-mediated interactions between belowground and aboveground insect herbivores

    NARCIS (Netherlands)

    Papadopoulou, G.V.; Dam, N.M. van

    2017-01-01

    Plant-mediated interactions between belowground (BG) and aboveground (AG) herbivores have received increasing interest recently. However, the molecular mechanisms underlying ecological consequences of BG–AG interactions are not fully clear yet. Herbivore-induced plant defenses are complex and

  4. Digital technology use among disadvantaged Australians: implications for equitable consumer participation in digitally-mediated communication and information exchange with health services.

    Science.gov (United States)

    Newman, Lareen; Biedrzycki, Kate; Baum, Fran

    2012-05-01

    To present research findings on access to, and use of, digital information and communication technologies (ICTs) by Australians from lower income and disadvantaged backgrounds to determine implications for equitable consumer access to digitally-mediated health services and information. Focus groups were held in 2008-09 with 80 residents from lower income and disadvantaged backgrounds in South Australia, predominantly of working- and family-formation age (25 to 55 years). Qualitative analysis was conducted on a-priori and emergent themes to describe dominant categories. Access to, and use of, computers, the Internet and mobile phones varied considerably in extent, frequency and quality within and across groups due to differences in abilities, resources and life experience. Barriers and facilitators included English literacy (including for native speakers), technological literacy, education, income, housing situation, social connection, health status, employment status, and trust. Many people gained ICT skills by trial and error or help from friends, and only a few from formal programs, resulting in varied skills. The considerable variation in ICT access and use within lower income and disadvantaged groups must be acknowledged and accommodated by health initiatives and services when delivering digitally-mediated consumer-provider interaction, online health information, or online self-management of health conditions. If services require consumers to participate in a digitally-mediated communication exchange, then we suggest they might support skills and technology acquisition, or provide non-ICT alternatives, in order to avoid exacerbating health inequities.

  5. Interactive uncertainty reduction strategies and verbal affection in computer-mediated communication

    NARCIS (Netherlands)

    Antheunis, M.L.; Schouten, A.P.; Valkenburg, P.M.; Peter, J.

    2012-01-01

    The goal of this study was to investigate the language-based strategies that computer-mediated communication (CMC) users employ to reduce uncertainty in the absence of nonverbal cues. Specifically, this study investigated the prevalence of three interactive uncertainty reduction strategies (i.e.,

  6. A framework for interactive learning in emerging technologies

    OpenAIRE

    Rens L.J. Vandeberg; Ellen H.M. Moors

    2008-01-01

    Innovation is an interactive learning process which is of special interest for emerging technologies in which complex complementary knowledge from heterogeneous stakeholders is combined. In the emerging phase of technology development a lot of knowledge is tacit and can only be transferred face-to-face. At the same time a shared vision between stakeholders is being formed that acts as a driver for innovation. Although the importance of interactive learning is widely acknowledged, an adequate ...

  7. Autonomic nervous system mediated effects of food intake. Interaction between gastrointestinal and cardiovascular systems.

    NARCIS (Netherlands)

    van Orshoven, N.P.

    2008-01-01

    The studies presented in this thesis focused on the autonomic nervous system mediated interactions between the gastrointestinal and cardiovascular systems in response to food intake and on potential consequences of failure of these interactions. The effects of food intake on cardiovascular

  8. Spin-offs from laser ablation in art conservation

    Science.gov (United States)

    Asmus, J.; Elford, J.; Parfenov, V.

    2013-05-01

    In 1973 The Center for Art Conservation Studies (CASS) was established at the University of California, San Diego (UCSD). This was in response to demonstrations that were conducted during January-March 1972 in Venice for UNESCO, Venice in Peril, International Fund for Monuments, and the Italian Petroleum Institute (ENI). The feasibility investigation explored in-situ pulsed holography, holographic interferometry, and laser ablation divestment for applications in art conservation practice. During subsequent decades scores of UCSD graduate and undergraduate students as well as conservators, conservation scientists, academics, and engineers who resided in CASS as "Visiting Scholars" contributed to advancing the understanding and performance of radiation technologies in the arts. Several technologies in addition to those involving optical wavelengths were also investigated to aid in art conservation and conservation science. Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR) were employed to detect and map moisture within masonry. Lead isotopic analyses revealed authenticity and provenance of Benin bronzes. Inside-out x-ray radiography facilitated the detection of defects in stone. Ultrasonic imaging was introduced for the mapping of fresco strata. Photoacoustic Spectroscopy (PAS) was used to characterize varnish layers on paintings. Digital image processing was introduced in order to detect and visualize pentimenti within paintings as well as to perform virtual restoration and provide interactive museum displays. Holographic images were employed as imaginary theater sets. In the years that followed the graduation of students and the visits of professional collaborators, numerous other applications of radiation ablation began appearing in a wide variety of other fields such as aircraft maintenance, ship maintenance, toxic chemical remediation, biological sterilization, food processing, industrial fabrication, industrial maintenance, nuclear

  9. p62 regulates CD40-mediated NFκB activation in macrophages through interaction with TRAF6

    Energy Technology Data Exchange (ETDEWEB)

    Seibold, Kristina; Ehrenschwender, Martin, E-mail: martin.ehrenschwender@ukr.de

    2015-08-14

    CD40 is a member of the tumor necrosis factor (TNF) receptor family. Activation-induced recruitment of adapter proteins, so-called TNF-receptor-associated factors (TRAFs) to the cytoplasmic tail of CD40 triggers signaling cascades important in the immune system, but has also been associated with excessive inflammation in diseases such as atherosclerosis and rheumatoid arthritis. Especially, pro-inflammatory nuclear factor κB (NFκB) signaling emanating from CD40-associated TRAF6 appears to be a key pathogenic driving force. Consequently, targeting the CD40-TRAF6 interaction is emerging as a promising therapeutic strategy, but the underlying molecular machinery of this signaling axis is to date poorly understood. Here, we identified the multifunctional adaptor protein p62 as a critical regulator in CD40-mediated NFκB signaling via TRAF6. CD40 activation triggered formation of a TRAF6-p62 complex. Disturbing this interaction tremendously reduced CD40-mediated NFκB signaling in macrophages, while TRAF6-independent signaling pathways remained unaffected. This highlights p62 as a potential target in hyper-inflammatory, CD40-associated pathologies. - Highlights: • CD40 activation triggers interaction of the adapter protein TRAF6 with p62. • TRAF6-p62 interaction regulates CD40-mediated NFκB signaling in macrophages. • Defective TRAF6-p62 interaction reduces CD40-mediated NFκB activation in macrophages.

  10. (2012 30 Windsor Y B Access Just 103 A VIEW FROM WITHIN: RECONCEPTUALIZING MEDIATOR INTERACTIONS

    Directory of Open Access Journals (Sweden)

    Debbie De Girolamo

    2012-10-01

    Full Text Available This paper explores mediator interactions from within the mediation process. It is difficult to obtain access to mediations due to issues of confidentiality and litigation privilege, thus restricting direct empirical research. During a yearlong ethnographic study during which the author was a participant-observer of a number of commercial mediations, the nature of mediations was explored from an independent observational perspective – separate from the process yet within the process. In this study, real life patterns of interactions are examined through case study analysis. It offers a reconceptualization of the nature of mediator interventions, one that moves beyond the accepted understanding of third party intervention. It suggests that the mediator has a fugitive identity in mediation, reflecting a traditional neutral third party intervener role, a party role and an adviser role. Dans le présent document, l‟auteure explore les interactions des médiateurs dans le cadre du processus de médiation. Il est difficile d‟obtenir l‟accès aux séances de médiation en raison du secret professionnel et du privilège relatif au litige, et cette difficulté limite la recherche empirique directe. Au cours d‟une étude ethnographique qui s‟est déroulée sur une année et à laquelle l‟auteure a participé comme observatrice d‟un certain nombre de médiations commerciales, la nature des médiations a été explorée d‟un point de vue observationnel indépendant – distinct du processus bien qu‟au sein du processus. Dans la présente étude, des situations réelles d‟interaction sont examinées au moyen de l‟analyse d‟études de cas. L‟auteure offre une reconceptualisation de la nature des interventions du médiateur, qui va au-delà de ce qui est reconnu comme l‟intervention d‟une tierce partie. Le médiateur aurait une identité fugace dans le processus de médiation, cette identité s‟expliquant par un r

  11. Evidence for water-mediated mechanisms in coral–algal interactions

    Science.gov (United States)

    Jorissen, Hendrikje; Skinner, Christina; Osinga, Ronald; de Beer, Dirk

    2016-01-01

    Although many coral reefs have shifted from coral-to-algal dominance, the consequence of such a transition for coral–algal interactions and their underlying mechanisms remain poorly understood. At the microscale, it is unclear how diffusive boundary layers (DBLs) and surface oxygen concentrations at the coral–algal interface vary with algal competitors and competitiveness. Using field observations and microsensor measurements in a flow chamber, we show that coral (massive Porites) interfaces with thick turf algae, macroalgae, and cyanobacteria, which are successful competitors against coral in the field, are characterized by a thick DBL and hypoxia at night. In contrast, coral interfaces with crustose coralline algae, conspecifics, and thin turf algae, which are poorer competitors, have a thin DBL and low hypoxia at night. Furthermore, DBL thickness and hypoxia at the interface with turf decreased with increasing flow speed, but not when thick turf was upstream. Our results support the importance of water-mediated transport mechanisms in coral–algal interactions. Shifts towards algal dominance, particularly dense assemblages, may lead to thicker DBLs, higher hypoxia, and higher concentrations of harmful metabolites and pathogens along coral borders, which in turn may facilitate algal overgrowth of live corals. These effects may be mediated by flow speed and orientation. PMID:27512146

  12. Natural Interaction Based Online Military Boxing Learning System

    Science.gov (United States)

    Yang, Chenglei; Wang, Lu; Sun, Bing; Yin, Xu; Wang, Xiaoting; Liu, Li; Lu, Lin

    2013-01-01

    Military boxing, a kind of Chinese martial arts, is widespread and health beneficial. In this paper, the authors introduce a military boxing learning system realized by 3D motion capture, Web3D and 3D interactive technologies. The interactions with the system are natural and intuitive. Users can observe and learn the details of each action of the…

  13. A state of the art on metallic fuel technology development

    International Nuclear Information System (INIS)

    Hwang, Woan; Kang, Hee Young; Nam, Cheol; Kim, Jong Oh

    1997-01-01

    Since worldwide interest turned toward ceramic fuels before the full potential of metallic fuel could be achieved in the late 1960's, the development of metallic fuels continued throughout the 1970's at ANL's experimental breeder reactor II (EBR-II) because EBR-II continued to be fueled with the metallic uranium-fissium alloy, U-5Fs. During this decade the performance limitations of metallic fuel were satisfactorily resolved resolved at EBR-II. The concept of the IFR developed at ANL since 1984. The technical feasibility had been demonstrated and the technology database had been established to support its practicality. One key features of the IFR is that the fuel is metallic, which brings pronounced benefits over oxide in improved inherent safety and lower processing costs. At the outset of the 1980's, it appeared that metallic fuels are recognized as a professed viable option with regard to safety, integral fuel cycle, waste minimization and deployment economics. This paper reviews the key advances in the last score and summarizes the state-of the art on metallic fuel technology development. (author). 29 refs., 1 tab

  14. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 3: Space power and thermal management

    International Nuclear Information System (INIS)

    1991-06-01

    Viewgraphs of briefings from the SSTAC/ARTS review of the draft integrated technology plan on thermal power and thermal management are presented. Topics covered include: space energy conversion research and technology; space photovoltaic energy conversion; chemical energy conversion and storage; thermal energy conversion; power management; thermal management; space nuclear power; high capacity power; surface power and thermal management; space platforms power and thermal management; and project SELENE

  15. Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb.

    Science.gov (United States)

    Wang, Wei; Yao, Xiao; Huang, Yan; Hu, Xiangming; Liu, Runzhong; Hou, Dongming; Chen, Ruichuan; Wang, Gang

    2013-01-01

    The Mediator is a multi-subunit complex that transduces regulatory information from transcription regulators to the RNA polymerase II apparatus. Growing evidence suggests that Mediator plays roles in multiple stages of eukaryotic transcription, including elongation. However, the detailed mechanism by which Mediator regulates elongation remains elusive. In this study, we demonstrate that Mediator MED23 subunit controls a basal level of transcription by recruiting elongation factor P-TEFb, via an interaction with its CDK9 subunit. The mRNA level of Egr1, a MED23-controlled model gene, is reduced 4-5 fold in Med23 (-/-) ES cells under an unstimulated condition, but Med23-deficiency does not alter the occupancies of RNAP II, GTFs, Mediator complex, or activator ELK1 at the Egr1 promoter. Instead, Med23 depletion results in a significant decrease in P-TEFb and RNAP II (Ser2P) binding at the coding region, but no changes for several other elongation regulators, such as DSIF and NELF. ChIP-seq revealed that Med23-deficiency partially reduced the P-TEFb occupancy at a set of MED23-regulated gene promoters. Further, we demonstrate that MED23 interacts with CDK9 in vivo and in vitro. Collectively, these results provide the mechanistic insight into how Mediator promotes RNAP II into transcription elongation.

  16. Science Walden: Exploring the Convergence of Environmental Technologies with Design and Art

    Directory of Open Access Journals (Sweden)

    Hyun-Kyung Lee

    2016-12-01

    Full Text Available Science Walden, which is inspired by two prominent literary works, namely, Walden by Henry David Thoreau (1817–1862 and Walden Two by Burrhus Frederic Skinner (1904–1990, is aimed at establishing a community that embodies humanistic values while embracing scientific advancement to produce renewable energy and water sources. This study attempts to capitalize on feces standard money (FSM and artistic collaboration between scientists and artists as a means of achieving the forms of life depicted in Walden and Walden Two. On our campus, we designed and built a pavilion that serves as a laboratory where scientific advantages, design, and art are merged. In the pavilion, feces are processed in reactors and facilities for sustainable energy production, and rainwater is harvested and treated for use in daily life. Our application of design and art contributes to easing interaction between the general public and scientists because it visualizes an ambiguous theory and concretizes it into an understandable image.

  17. When a Body Meets a Body: An Exploration of the Negative Impact of Social Interactions on Museum Experiences of Art

    Science.gov (United States)

    Pelowski, Matthew; Liu, Tao; Palacios, Victor; Akiba, Fuminori

    2014-01-01

    We consider the phenomenon of social interactions within the art museum, arguing that even the bare possibility of meeting others or intruding into their gaze can have a profoundly detrimental effect on art experience. This is done by tracing a finding from our previous studies in which we considered three museum galleries--each with the same…

  18. Internet-Mediated Technologies and Mixed Methods Research: Problems and Prospects

    Science.gov (United States)

    Hesse-Biber, Sharlene; Griffin, Amy J.

    2013-01-01

    This article provides an examination of a range of mixed methods research projects that employ Internet-mediated technologies (IMT) for data collection. Using a case study approach, this article allows for the uncovering of a process by which IMT are used as a data collection medium in mixed methods praxis. Under the theoretical position of medium…

  19. Maqasid al-Shariah as a Complementary Framework for Conventional Bioethics: Application in Malaysian Assisted Reproductive Technology (ART) Fatwa.

    Science.gov (United States)

    Ibrahim, Abdul Halim; Rahman, Noor Naemah Abdul; Saifuddeen, Shaikh Mohd

    2017-09-11

    Rapid development in the area of assisted reproductive technology (ART), has benefited mankind by addressing reproductive problems. However, the emergence of new technologies and techniques raises various issues and discussions among physicians and the masses, especially on issues related to bioethics. Apart from solutions provided using conventional bioethics framework, solutions can also be derived via a complementary framework of bioethics based on the Higher Objectives of the Divine Law (Maqasid al-Shariah) in tackling these problems. This approach in the Islamic World has been applied and localised in the Malaysian context. Thus, this paper highlights a conceptual theoretical framework for solving current bioethical issues, with a special focus on ART in the Malaysian context, and compares this theory with conventional theories of bioethics.

  20. Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein–Protein Interaction Analysis, and Protein Function Exploration

    Directory of Open Access Journals (Sweden)

    Els Beghein

    2017-07-01

    Full Text Available Over the last two decades, nanobodies or single-domain antibodies have found their way in research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid heavy chain only antibodies, possess remarkable characteristics that favor their use over conventional antibodies or fragments thereof, in selected areas of research. In this review, we assess the current status of nanobodies as research tools in diverse aspects of fundamental research. We discuss the use of nanobodies as detection reagents in fluorescence microscopy and focus on recent advances in super-resolution microscopy. Second, application of nanobody technology in investigating protein–protein interactions is reviewed, with emphasis on possible uses in mass spectrometry. Finally, we discuss the potential value of nanobodies in studying protein function, and we focus on their recently reported application in targeted protein degradation. Throughout the review, we highlight state-of-the-art engineering strategies that could expand nanobody versatility and we suggest future applications of the technology in the selected areas of fundamental research.

  1. Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein-Protein Interaction Analysis, and Protein Function Exploration.

    Science.gov (United States)

    Beghein, Els; Gettemans, Jan

    2017-01-01

    Over the last two decades, nanobodies or single-domain antibodies have found their way in research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid heavy chain only antibodies, possess remarkable characteristics that favor their use over conventional antibodies or fragments thereof, in selected areas of research. In this review, we assess the current status of nanobodies as research tools in diverse aspects of fundamental research. We discuss the use of nanobodies as detection reagents in fluorescence microscopy and focus on recent advances in super-resolution microscopy. Second, application of nanobody technology in investigating protein-protein interactions is reviewed, with emphasis on possible uses in mass spectrometry. Finally, we discuss the potential value of nanobodies in studying protein function, and we focus on their recently reported application in targeted protein degradation. Throughout the review, we highlight state-of-the-art engineering strategies that could expand nanobody versatility and we suggest future applications of the technology in the selected areas of fundamental research.

  2. Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein–Protein Interaction Analysis, and Protein Function Exploration

    Science.gov (United States)

    Beghein, Els; Gettemans, Jan

    2017-01-01

    Over the last two decades, nanobodies or single-domain antibodies have found their way in research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid heavy chain only antibodies, possess remarkable characteristics that favor their use over conventional antibodies or fragments thereof, in selected areas of research. In this review, we assess the current status of nanobodies as research tools in diverse aspects of fundamental research. We discuss the use of nanobodies as detection reagents in fluorescence microscopy and focus on recent advances in super-resolution microscopy. Second, application of nanobody technology in investigating protein–protein interactions is reviewed, with emphasis on possible uses in mass spectrometry. Finally, we discuss the potential value of nanobodies in studying protein function, and we focus on their recently reported application in targeted protein degradation. Throughout the review, we highlight state-of-the-art engineering strategies that could expand nanobody versatility and we suggest future applications of the technology in the selected areas of fundamental research. PMID:28725224

  3. Sustainability, cognitive technologies and the digital semiosphere

    DEFF Research Database (Denmark)

    Bruni, Luis Emilio

    2015-01-01

    The convergence of digital and multimodal cognitive technologies offers the possibility to interact in an ‘on-line’ cultural process mediated by new ways of representing our thoughts, emotions, ideas, beliefs, opinions and behaviours. Such technological integration not only alters and introduces...

  4. Technology Mediated Instruction and its Effect on Cognitive Scaffolding, motivation and Academic Performance in EFL Context

    Directory of Open Access Journals (Sweden)

    Sepideh Berenji

    2017-11-01

    Full Text Available Technology mediated learning brings together the users with shared interests. This method makes learners informally engaged in language learning. This study intended to investigate the effect of technology mediated instruction on cognitive scaffolding, academic performance and motivation. Employing a quasi-experimental research, 80 learners from two intact classes at Islamic Azad University, Osku Branch were selected as the experimental and control groups. Telegram as a tool was used in the experimental group, while the control group received traditional way of instruction. Critical ethnography approach was implemented to consider the amount of cognitive scaffolding. To measure the students’ motivational level in both groups, Course Interest Survey (CIS was administered at the end of the semester. The total average score for each group was calculated. To compare students’ academic achievement, their average scores in the final academic test were considered. An Independent samples t-test in was used to compare the mean scores. The results indicated that technology mediated learning brought about cognitive scaffolding and the students in the experimental group outperformed the control group in terms of motivation and academic achievement. The results of the study suggest that to bring about academically successful students, practitioners should use technology mediated instruction.

  5. Developmental Transformations Art Therapy: An Embodied, Interactional Approach

    Science.gov (United States)

    Rosen, Marni; Pitre, Renée; Johnson, David Read

    2016-01-01

    A new method of art therapy is described, based on Developmental Transformations, in which the therapist participates in joint art making with a client. The therapist's task is to present a graduated set of interpersonal demands on the client through the artwork, helping the client find adaptive responses to accommodations required by others, as…

  6. Ceramic dental biomaterials and CAD/CAM technology: state of the art.

    Science.gov (United States)

    Li, Raymond Wai Kim; Chow, Tak Wah; Matinlinna, Jukka Pekka

    2014-10-01

    Ceramics are widely used as indirect restorative materials in dentistry because of their high biocompatibility and pleasing aesthetics. The objective is to review the state of the arts of CAD/CAM all-ceramic biomaterials. CAD/CAM all-ceramic biomaterials are highlighted and a subsequent literature search was conducted for the relevant subjects using PubMed followed by manual search. Developments in CAD/CAM technology have catalyzed researches in all-ceramic biomaterials and their applications. Feldspathic glass ceramic and glass infiltrated ceramic can be fabricated by traditional laboratory methods or CAD/CAM. The advent of polycrystalline ceramics is a direct result of CAD/CAM technology without which the fabrication would not have been possible. The clinical uses of these ceramics have met with variable clinical success. Multiple options are now available to the clinicians for the fabrication of aesthetic all ceramic restorations. Copyright © 2014 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  7. The Digital Economy: Social Interaction Technologies – an Overview

    Directory of Open Access Journals (Sweden)

    Teófilo Redondo

    2015-03-01

    Full Text Available Social interaction technologies (SIT is a very broad field that encompasses a large list of topics: interactive and networked computing, mobile social services and the Social Web, social software and social media, marketing and advertising, various aspects and uses of blogs and podcasting, corporate value and web-based collaboration, e-government and online democracy, virtual volunteering, different aspects and uses of folksonomies, tagging and the social semantic cloud of tags, blog-based knowledge management systems, systems of online learning, with their ePortfolios, blogs and wikis in education and journalism, legal issues and social interaction technology, dataveillance and online fraud, neogeography, social software usability, social software in libraries and nonprofit organizations, and broadband visual communication technology for enhancing social interaction. The fact is that the daily activities of many businesses are being socialized, as is the case with Yammer (https://www.yammer.com/, the social enterprise social network. The leitmotivs of social software are: create, connect, contribute, and collaborate.

  8. The Mediating Role of Knowledge Sharing on Information Technology and Innovation

    Directory of Open Access Journals (Sweden)

    Onwika Kaewchur

    2013-12-01

    Full Text Available This study aims to investigate the relationship between information technology, knowledge sharing, and a firm’s innovation. Knowledge sharing as a mediating effect is also simultaneously investigated with regard to the relationship between information technology and a firm’s innovation. In this research, the quantitative method was mainly employed. The data was collected with a survey. A total of 224 respondents from herbal manufacturing companies were included in the research. The results presented in this paper demonstrate that knowledge sharing and information technology can critically influence the organization’s innovation and can play a vital role as a significant success factor in this process.

  9. DIBS: a repository of disordered binding sites mediating interactions with ordered proteins.

    Science.gov (United States)

    Schad, Eva; Fichó, Erzsébet; Pancsa, Rita; Simon, István; Dosztányi, Zsuzsanna; Mészáros, Bálint

    2018-02-01

    Intrinsically Disordered Proteins (IDPs) mediate crucial protein-protein interactions, most notably in signaling and regulation. As their importance is increasingly recognized, the detailed analyses of specific IDP interactions opened up new opportunities for therapeutic targeting. Yet, large scale information about IDP-mediated interactions in structural and functional details are lacking, hindering the understanding of the mechanisms underlying this distinct binding mode. Here, we present DIBS, the first comprehensive, curated collection of complexes between IDPs and ordered proteins. DIBS not only describes by far the highest number of cases, it also provides the dissociation constants of their interactions, as well as the description of potential post-translational modifications modulating the binding strength and linear motifs involved in the binding. Together with the wide range of structural and functional annotations, DIBS will provide the cornerstone for structural and functional studies of IDP complexes. DIBS is freely accessible at http://dibs.enzim.ttk.mta.hu/. The DIBS application is hosted by Apache web server and was implemented in PHP. To enrich querying features and to enhance backend performance a MySQL database was also created. dosztanyi@caesar.elte.hu or bmeszaros@caesar.elte.hu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press.

  10. Fall prevention intervention technologies: A conceptual framework and survey of the state of the art.

    Science.gov (United States)

    Hamm, Julian; Money, Arthur G; Atwal, Anita; Paraskevopoulos, Ioannis

    2016-02-01

    In recent years, an ever increasing range of technology-based applications have been developed with the goal of assisting in the delivery of more effective and efficient fall prevention interventions. Whilst there have been a number of studies that have surveyed technologies for a particular sub-domain of fall prevention, there is no existing research which surveys the full spectrum of falls prevention interventions and characterises the range of technologies that have augmented this landscape. This study presents a conceptual framework and survey of the state of the art of technology-based fall prevention systems which is derived from a systematic template analysis of studies presented in contemporary research literature. The framework proposes four broad categories of fall prevention intervention system: Pre-fall prevention; Post-fall prevention; Fall injury prevention; Cross-fall prevention. Other categories include, Application type, Technology deployment platform, Information sources, Deployment environment, User interface type, and Collaborative function. After presenting the conceptual framework, a detailed survey of the state of the art is presented as a function of the proposed framework. A number of research challenges emerge as a result of surveying the research literature, which include a need for: new systems that focus on overcoming extrinsic falls risk factors; systems that support the environmental risk assessment process; systems that enable patients and practitioners to develop more collaborative relationships and engage in shared decision making during falls risk assessment and prevention activities. In response to these challenges, recommendations and future research directions are proposed to overcome each respective challenge. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  11. A Multi-Case Study of University Students' Language-Learning Experience Mediated by Mobile Technologies: A Socio-Cultural Perspective

    Science.gov (United States)

    Ma, Qing

    2017-01-01

    Emerging mobile technologies can be considered a new form of social and cultural artefact that mediates people's language learning. This multi-case study investigates how mobile technologies mediate a group of Hong Kong university students' L2 learning, which serves as a lens with which to capture the personalised, unique, contextual and…

  12. ENGage: The use of space and pixel art for increasing primary school children's interest in science, technology, engineering and mathematics

    Science.gov (United States)

    Roberts, Simon J.

    2014-01-01

    The Faculty of Engineering at The University of Nottingham, UK, has developed interdisciplinary, hands-on workshops for primary schools that introduce space technology, its relevance to everyday life and the importance of science, technology, engineering and maths. The workshop activities for 7-11 year olds highlight the roles that space and satellite technology play in observing and monitoring the Earth's biosphere as well as being vital to communications in the modern digital world. The programme also provides links to 'how science works', the environment and citizenship and uses pixel art through the medium of digital photography to demonstrate the importance of maths in a novel and unconventional manner. The interactive programme of activities provides learners with an opportunity to meet 'real' scientists and engineers, with one of the key messages from the day being that anyone can become involved in science and engineering whatever their ability or subject of interest. The methodology introduces the role of scientists and engineers using space technology themes, but it could easily be adapted for use with any inspirational topic. Analysis of learners' perceptions of science, technology, engineering and maths before and after participating in ENGage showed very positive and significant changes in their attitudes to these subjects and an increase in the number of children thinking they would be interested and capable in pursuing a career in science and engineering. This paper provides an overview of the activities, the methodology, the evaluation process and results.

  13. Theory and state-of-the-art technology of software reliability

    International Nuclear Information System (INIS)

    Suzudo, Tomoaki; Watanabe, Norio

    1999-11-01

    Since FY 1997 , the Japan Atomic Energy Research Institute has been conducting a project , Study on Reliability of Digital I and C Systems. As part of the project , the methodologies and tools to improve software reliability were reviewed in order to examine the theory and the state-of-the-art technology in this field. It is surmised, as results from the review, that computerized software design and implementation tool (CASE tool), algebraic analysis to ensure the consistency between software requirement framework and its detailed design specification, and efficient test method using the internal information of the software (white-box test) at the validation phase just before the completion of the development will play a key role to enhance software reliability in the future. (author)

  14. Interactive Contemporary Art : Participation in Practice

    NARCIS (Netherlands)

    Brown, K.J.

    2014-01-01

    Audience participation has polarized the critical debate surrounding contemporary art's social, moral and aesthetic potential. This incisive collection of essays sheds new light on the political, ethical and artistic capacity of participatory works and tests the most recent theoretical approaches to

  15. Separating monocular and binocular neural mechanisms mediating chromatic contextual interactions.

    Science.gov (United States)

    D'Antona, Anthony D; Christiansen, Jens H; Shevell, Steven K

    2014-04-17

    When seen in isolation, a light that varies in chromaticity over time is perceived to oscillate in color. Perception of that same time-varying light may be altered by a surrounding light that is also temporally varying in chromaticity. The neural mechanisms that mediate these contextual interactions are the focus of this article. Observers viewed a central test stimulus that varied in chromaticity over time within a larger surround that also varied in chromaticity at the same temporal frequency. Center and surround were presented either to the same eye (monocular condition) or to opposite eyes (dichoptic condition) at the same frequency (3.125, 6.25, or 9.375 Hz). Relative phase between center and surround modulation was varied. In both the monocular and dichoptic conditions, the perceived modulation depth of the central light depended on the relative phase of the surround. A simple model implementing a linear combination of center and surround modulation fit the measurements well. At the lowest temporal frequency (3.125 Hz), the surround's influence was virtually identical for monocular and dichoptic conditions, suggesting that at this frequency, the surround's influence is mediated primarily by a binocular neural mechanism. At higher frequencies, the surround's influence was greater for the monocular condition than for the dichoptic condition, and this difference increased with temporal frequency. Our findings show that two separate neural mechanisms mediate chromatic contextual interactions: one binocular and dominant at lower temporal frequencies and the other monocular and dominant at higher frequencies (6-10 Hz).

  16. The Tools, Approaches and Applications of Visual Literacy in the Visual Arts Department of Cross River University of Technology, Calabar, Nigeria

    Science.gov (United States)

    Ecoma, Victor

    2016-01-01

    The paper reflects upon the tools, approaches and applications of visual literacy in the Visual Arts Department of Cross River University of Technology, Calabar, Nigeria. The objective of the discourse is to examine how the visual arts training and practice equip students with skills in visual literacy through methods of production, materials and…

  17. The good field trip: How elementary students from diverse socio-economic backgrounds learn science, art, and technology at a museum

    Science.gov (United States)

    Martell, Sandra Toro

    The Good Field Trip is a study that uses an ethnographic approach to answer the question of what learning looks like during a field trip to a museum. The study uses the Contextual Model of Learning (Falk & Dierking, 2000) to investigate elementary students' personal, physical, and sociocultural contexts of learning as well as how time affects students' thoughts and feelings about the experience. The author accompanied a group of eight students on a three and a half day camp-like experience to a museum that promotes environmental stewardship and the integration of art, science, and technology use and learning. The author videotaped the students' conversations and experiences and interviewed students before, during, and after the trip. Analyses of the videotapes were supplemented with student documents, including comic books, journal notes, and reflective essays about the trip. Findings include that not all experiences are marked as science, art, and technology; technology use does not occur; art is presented in a more formalized manner than science, which is composed of observation and the acquisition of knowledge about plants and animals; and conversations and activities resemble traditional modes of learning in school settings.

  18. Designing interactive technology for crowd experiences - beyond sanitization

    DEFF Research Database (Denmark)

    Veerasawmy, Rune

    2014-01-01

    This dissertation concerns the topic on designing interactive technology for crowd expe- riences. It takes the outset in the experience-oriented design approach within interaction design, exploring the research question how can we conceptually understand and design interactive technology for crowd...... experiences? Through theoretical studies of sociological crowd theory and pragmatist perspectives on experience combined with design exper- iments at sporting events this dissertation establishes an conceptual understanding of crowd experience. The outcome of this work is furthermore synthesized...... in a conceptual model of social experiences that presents crowd experiences as a distinct type of social experience. This is different from what previously have been explored within experi- ence-oriented design. This dissertation is composed of four research papers framed by an overview that summarizes...

  19. Art in the Service of Science

    Science.gov (United States)

    Asmus, J. F.

    In fields such as studio art, art conservation, archaeology, anthropology, music, and architecture it is often understood that many of the advances emerge from the introduction of new developments from science and technology. Scientific research is often justified on the basis of its past as well as potential future fallout into other endeavors as diverse as medicine, manufacturing, and the humanities. The diffusion of scientific innovation into the practice of art conservation has been punctuated by the introduction of a series of diverse technologies. Trace element and isotopic analyses, infrared imaging, ultraviolet fluorescence inspection, advanced coatings and adhesives, scanning electron microscopy, and photon/electron microprobes are notable examples. For the past thirty years various laser technologies have demonstrated utility in the practice of art conservation, as well. These include photon cleaning and divestment, holographic display and nondestructive analysis, surface characterization through laser fluorescence, radiation scattering and absorption, as well as laser-induced ultrasound. At the dawn of laser technology's introduction into the art conservation field (1972-74) the Center for Art/Science Studies (CASS) was established at the University of California, San Diego (UCSD) with the hope of accelerating and broadening the diffusion of scientific developments into art conservation practice. Surprisingly, one of the first events in the CASS/UCSD transpired when a Visual Arts Department student employed a primitive laser statue cleaner to "correct" a silk-screen print. In the course of maintaining her laser this art student discovered a dramatically improved method for aligning the complex optical beam train by utilizing her artistic training. A few months later another CASS/UCSD student in the Photographic Arts Program (while modifying a ruby laser to experiment with theater-lighting special effects) discovered an improved laser beam

  20. Using interactive video technology in nursing education: a pilot study.

    Science.gov (United States)

    Zerr, Daria M; Pulcher, Karen L

    2008-02-01

    A pilot study was conducted to analyze the benefits of using interactive technology with external assessors and graduating senior nursing students during Senior Nurse Leadership Assessment Day at the University of Central Missouri. The primary aim was to determine whether videoconferencing technology would promote recruitment and retention of professional nurse external assessors without compromising student learning. Among the issues discussed are the advantages and disadvantages of using interactive videoconferencing technology in education and the influence of external assessors in nursing education. The study results indicate that interactive videoconferencing is an effective, accepted format for educational opportunities such as Senior Nurse Leadership Assessment Day, based on the lived experiences of the study participants. In addition, the results demonstrate that interactive videoconferencing does not compromise student learning or assessment by external assessors.

  1. Evolutionists and Australian Aboriginal art: 1885-1915

    Directory of Open Access Journals (Sweden)

    Susan Lowish

    2015-06-01

    Full Text Available This paper examines key examples of writing about Australian Aboriginal art in the decades around 1900 specifically in relation to the way in which it is used to provide evidence for theories concerning the evolution of art. Analysis of published works by late nineteenth-century men of science reveals the main influences shaping their perceptions of Aboriginal art during this time and provides an early working definition of this emerging category. This paper confirms that turn-of-the-century European understandings of Aboriginal art were based on limited evidence mediated through a specifically ethnographic notion of ‘decorative art’.

  2. New Media Art at the Intersection between Technology and Politics and the Social Conditions

    OpenAIRE

    Ertuğrul, Gökçen

    2016-01-01

    This article, by problematising the relationship between technology, art and the socialconditions, aims to examine the ways through which new artistic positions are emergingwithin digital capitalist conditions. The postfordist society of control works with digitaltechnologies and this has produced mechanisms of bio-power which are articulatedaround the code. Under the conditions of digital culture in which social relations areorganised around the network structure, an examination of the manif...

  3. Interactive simulation of technology management foresight

    DEFF Research Database (Denmark)

    Hansen, Mette Sanne; Rasmussen, Lauge Baungaard; Jacobsen, Peter

    2013-01-01

    of either qualitative or quantitative processes due to the complexity and uncertainty of the more or less interrelated technology tracks. Accordingly, the foresight approach must allow for interaction between the real-world system and the model builders, for example by using an interacting narrative...... is often occurring in companies. The use of CSA makes it possible for management to close the often experienced knowledge and activity gaps between the strategic, tactical and operational levels in a company. The outcome of developing and using CSA is a generic approach that enables the interaction between...... narrative simulation (scenarios) and numerical simulation. These interactive processes can take place on the strategic, tactical and operational levels of an organization and thus contribute to close the gaps that often exist between these levels. The combined foresight simulation approach is, however...

  4. Technological mediation as a learning tool for writing and reading

    Directory of Open Access Journals (Sweden)

    Gladys Molano Caro

    2015-12-01

    Full Text Available This article disclosed the progress a technological mediation has built to the adquisition, use and development of reading and writing from Cognitive Affective Method for Learning -MACPA-. A development like the one being proposed, is an option for children and young people to, activate, promote, develop and / or enhance the learning of reading and writing. Likewise, it is an option to consider the results achieved in the PISA test and case reports, done by teachers by teachers, showing that that elementary students do not perform production of texts so spontaneous or directed; and they fail to make progress in reading comprehension levels. Given this context, the partial results achieved in the second phase of the research aims to implement a technology platform based mediation MACPA as an educational resource to enhance the processes of reading and writing among students from first to fourth grades of primary education. Accordingly, through Article basis be found in a software for reading and writing that takes into account the particularities of learning of students with intellectual disabilities, learning disabilities in students who have not evidenced difficulties in academic learning processes, though they require a new method to accelerate learning.

  5. art@CMS SciArt Workshops

    CERN Document Server

    Hoch, Michael; Preece, Stephen; Storr, Mick; Petrilli, Achille

    2017-01-01

    Recent developments in science education policy and practice suggest that successful learning in the 21st century requires the horizontal connectedness across areas of knowledge by linking the arts and humanities with science, technology, engineering and mathematics (STEM) subjects. The rapidly increasing STEAM movement calls for arts integration into science teaching and learning to help school students develop skills that are necessary to thrive in an innovation economy. Education and outreach in high - energy physics are not an exception to these developments. This paper outlines a series of learning activities for students at secondary and tertiary level that use a cross - disciplinary approach to fostering creativity and imagination in physics education and outreach.

  6. art@CMS SciArt Workshops

    CERN Document Server

    Hoch, Michael; Preece, Stephen; Storr, Mick; Petrilli, Achille

    2016-01-01

    Recent developments in science education policy and practice suggest that successful learning in the 21st century requires the horizontal connectedness across areas of knowledge by linking the arts and humanities with science, technology, engineering and mathematics (STEM) subjects. The rapidly increasing STEAM movement calls for arts integration into science teaching and learning to help school students develop skills that are necessary to thrive in an innovation economy. Education and outreach in high - energy physics are not an exception to these developments. This paper outlines a series of learning activities for students at secondary and tertiary level that use a cross - disciplinary approach to fostering creativity and imagination in physics education and outreach.

  7. Web 2.0 Technologies and Parent Involvement of ELL Students: An Ecological Perspective

    Science.gov (United States)

    Shin, Dong-shin; Seger, Wendy

    2016-01-01

    This study explores how ELL students' parents participated in a blog-mediated English language arts curriculum in a second grade classroom at a U.S. urban school, and how they supported their children's learning of school-based writing. Adopting ecological perspectives on technological affordances, this study views digital literacy as discursive…

  8. Causal mediation analysis with multiple causally non-ordered mediators.

    Science.gov (United States)

    Taguri, Masataka; Featherstone, John; Cheng, Jing

    2018-01-01

    In many health studies, researchers are interested in estimating the treatment effects on the outcome around and through an intermediate variable. Such causal mediation analyses aim to understand the mechanisms that explain the treatment effect. Although multiple mediators are often involved in real studies, most of the literature considered mediation analyses with one mediator at a time. In this article, we consider mediation analyses when there are causally non-ordered multiple mediators. Even if the mediators do not affect each other, the sum of two indirect effects through the two mediators considered separately may diverge from the joint natural indirect effect when there are additive interactions between the effects of the two mediators on the outcome. Therefore, we derive an equation for the joint natural indirect effect based on the individual mediation effects and their interactive effect, which helps us understand how the mediation effect works through the two mediators and relative contributions of the mediators and their interaction. We also discuss an extension for three mediators. The proposed method is illustrated using data from a randomized trial on the prevention of dental caries.

  9. A state of the art on metallic fuel technology development

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Woan; Kang, Hee Young; Nam, Cheol; Kim, Jong Oh [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    Since worldwide interest turned toward ceramic fuels before the full potential of metallic fuel could be achieved in the late 1960`s, the development of metallic fuels continued throughout the 1970`s at ANL`s experimental breeder reactor II (EBR-II) because EBR-II continued to be fueled with the metallic uranium-fissium alloy, U-5Fs. During this decade the performance limitations of metallic fuel were satisfactorily resolved resolved at EBR-II. The concept of the IFR developed at ANL since 1984. The technical feasibility had been demonstrated and the technology database had been established to support its practicality. One key features of the IFR is that the fuel is metallic, which brings pronounced benefits over oxide in improved inherent safety and lower processing costs. At the outset of the 1980`s, it appeared that metallic fuels are recognized as a professed viable option with regard to safety, integral fuel cycle, waste minimization and deployment economics. This paper reviews the key advances in the last score and summarizes the state-of the art on metallic fuel technology development. (author). 29 refs., 1 tab.

  10. A Proposal to Develop Interactive Classification Technology

    Science.gov (United States)

    deBessonet, Cary

    1998-01-01

    Research for the first year was oriented towards: 1) the design of an interactive classification tool (ICT); and 2) the development of an appropriate theory of inference for use in ICT technology. The general objective was to develop a theory of classification that could accommodate a diverse array of objects, including events and their constituent objects. Throughout this report, the term "object" is to be interpreted in a broad sense to cover any kind of object, including living beings, non-living physical things, events, even ideas and concepts. The idea was to produce a theory that could serve as the uniting fabric of a base technology capable of being implemented in a variety of automated systems. The decision was made to employ two technologies under development by the principal investigator, namely, SMS (Symbolic Manipulation System) and SL (Symbolic Language) [see debessonet, 1991, for detailed descriptions of SMS and SL]. The plan was to enhance and modify these technologies for use in an ICT environment. As a means of giving focus and direction to the proposed research, the investigators decided to design an interactive, classificatory tool for use in building accessible knowledge bases for selected domains. Accordingly, the proposed research was divisible into tasks that included: 1) the design of technology for classifying domain objects and for building knowledge bases from the results automatically; 2) the development of a scheme of inference capable of drawing upon previously processed classificatory schemes and knowledge bases; and 3) the design of a query/ search module for accessing the knowledge bases built by the inclusive system. The interactive tool for classifying domain objects was to be designed initially for textual corpora with a view to having the technology eventually be used in robots to build sentential knowledge bases that would be supported by inference engines specially designed for the natural or man-made environments in which the

  11. Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

    Science.gov (United States)

    Nishikawa, Joy L; Boeszoermenyi, Andras; Vale-Silva, Luis A; Torelli, Riccardo; Posteraro, Brunella; Sohn, Yoo-Jin; Ji, Fei; Gelev, Vladimir; Sanglard, Dominique; Sanguinetti, Maurizio; Sadreyev, Ruslan I; Mukherjee, Goutam; Bhyravabhotla, Jayaram; Buhrlage, Sara J; Gray, Nathanael S; Wagner, Gerhard; Näär, Anders M; Arthanari, Haribabu

    2016-02-25

    Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex. Aberrant function of transcription activators has been implicated in several diseases. However, therapeutic targeting efforts have been hampered by a lack of detailed molecular knowledge of the mechanisms of gene activation by disease-associated transcription activators. We previously identified an activator-targeted three-helix bundle KIX domain in the human MED15 Mediator subunit that is structurally conserved in Gal11/Med15 Mediator subunits in fungi. The Gal11/Med15 KIX domain engages pleiotropic drug resistance transcription factor (Pdr1) orthologues, which are key regulators of the multidrug resistance pathway in Saccharomyces cerevisiae and in the clinically important human pathogen Candida glabrata. The prevalence of C. glabrata is rising, partly owing to its low intrinsic susceptibility to azoles, the most widely used antifungal agent. Drug-resistant clinical isolates of C. glabrata most commonly contain point mutations in Pdr1 that render it constitutively active, suggesting that this transcriptional activation pathway represents a linchpin in C. glabrata multidrug resistance. Here we perform sequential biochemical and in vivo high-throughput screens to identify small-molecule inhibitors of the interaction of the C. glabrata Pdr1 activation domain with the C. glabrata Gal11A KIX domain. The lead compound (iKIX1) inhibits Pdr1-dependent gene activation and re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection. Determining the NMR structure of the C. glabrata Gal11A KIX domain provides a detailed understanding of the molecular mechanism of Pdr1 gene activation and multidrug resistance inhibition by iKIX1. We have demonstrated the feasibility of small-molecule targeting of a

  12. Human-computer interaction and management information systems

    CERN Document Server

    Galletta, Dennis F

    2014-01-01

    ""Human-Computer Interaction and Management Information Systems: Applications"" offers state-of-the-art research by a distinguished set of authors who span the MIS and HCI fields. The original chapters provide authoritative commentaries and in-depth descriptions of research programs that will guide 21st century scholars, graduate students, and industry professionals. Human-Computer Interaction (or Human Factors) in MIS is concerned with the ways humans interact with information, technologies, and tasks, especially in business, managerial, organizational, and cultural contexts. It is distinctiv

  13. Beyond knowledge and skills: the use of a Delphi study to develop a technology-mediated teaching strategy.

    Science.gov (United States)

    Rowe, Michael; Frantz, Jose; Bozalek, Vivienne

    2013-04-10

    While there is evidence to suggest that teaching practices in clinical education should include activities that more accurately reflect the real world, many educators base their teaching on transmission models that encourage the rote learning of knowledge and technical skills. Technology-mediated instruction may facilitate the development of professional attributes that go beyond "having" knowledge and skills, but there is limited evidence for how to integrate technology into these innovative teaching approaches. This study used a modified Delphi method to help identify the professional attributes of capable practitioners, the approaches to teaching that may facilitate the development of these attributes, and finally, how technology could be integrated with those teaching strategies in order to develop capable practitioners. Open-ended questions were used to gather data from three different expert panels, and results were thematically analysed. Clinical educators should not view knowledge, skills and attitudes as a set of products of learning, but rather as a set of attributes that are developed during a learning process. Participants highlighted the importance of continuing personal and professional development that emphasised the role of values and emotional response to the clinical context. To develop these attributes, clinical educators should use teaching activities that are learner-centred, interactive, integrated, reflective and that promote engagement. When technology-mediated teaching activities are considered, they should promote the discussion of clinical encounters, facilitate the sharing of resources and experiences, encourage reflection on the learning process and be used to access content outside the classroom. In addition, educational outcomes must drive the integration of technology into teaching practice, rather than the features of the technology. There is a need for a cultural change in clinical education, in which those involved with the

  14. The artist emerges: visual art learning alters neural structure and function.

    Science.gov (United States)

    Schlegel, Alexander; Alexander, Prescott; Fogelson, Sergey V; Li, Xueting; Lu, Zhengang; Kohler, Peter J; Riley, Enrico; Tse, Peter U; Meng, Ming

    2015-01-15

    How does the brain mediate visual artistic creativity? Here we studied behavioral and neural changes in drawing and painting students compared to students who did not study art. We investigated three aspects of cognition vital to many visual artists: creative cognition, perception, and perception-to-action. We found that the art students became more creative via the reorganization of prefrontal white matter but did not find any significant changes in perceptual ability or related neural activity in the art students relative to the control group. Moreover, the art students improved in their ability to sketch human figures from observation, and multivariate patterns of cortical and cerebellar activity evoked by this drawing task became increasingly separable between art and non-art students. Our findings suggest that the emergence of visual artistic skills is supported by plasticity in neural pathways that enable creative cognition and mediate perceptuomotor integration. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. A 2D suspension of active agents: the role of fluid mediated interactions

    International Nuclear Information System (INIS)

    Behmadi, Hojjat; Najafi, Ali; Fazli, Zahra

    2017-01-01

    Taking into account both the Vicsek short-range ordering and the far-field hydrodynamic interactions mediated by the ambient fluid, we investigate the role of long-range interactions in the ordering phenomena in a quasi 2-dimensional active suspension. By studying the number fluctuations, the velocity correlation functions and cluster size distribution function, we show that depending on the number density of swimmers and the strength of noise, the hydrodynamic interactions can have significant effects in a suspension. For a fixed value of noise, at larger density of particles, long-range interactions enhance the particle pairing and cluster formation in the system. (paper)

  16. Modern analytic methods applied to the art and archaeology; Metodos analiticos modernos aplicados al arte y la arqueologia

    Energy Technology Data Exchange (ETDEWEB)

    Tenorio C, M. D.; Longoria G, L. C., E-mail: dolores.tenorio@inin.gob.m [ININ, Departamento de Quimica, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2010-07-01

    The interaction of diverse areas as the analytic chemistry, the history of the art and the archaeology has allowed the development of a variety of techniques used in archaeology, in conservation and restoration. These methods have been used to date objects, to determine the origin of the old materials and to reconstruct their use and to identify the degradation processes that affect the integrity of the art works. The objective of this chapter is to offer a general vision on the researches that have been realized in the Instituto Nacional de Investigaciones Nucleares (ININ) in the field of cultural goods. A series of researches carried out in collaboration with national investigators and of the foreigner is described shortly, as well as with the great support of degree students and master in archaeology of the National School of Anthropology and History, since one of the goals that have is to diffuse the knowledge of the existence of these techniques among the young archaeologists, so that they have a wider vision of what they could use in an in mediate future and they can check hypothesis with scientific methods. (Author)

  17. Izvođenje umetničko/teorijskog rada u mediju hiperteksta – net art Marka Amerike / Performance of Artistic/Theoretical Work in Medium of Hypertext – Mark Amerika’s Net Art

    Directory of Open Access Journals (Sweden)

    Sanela Nikolić

    2014-10-01

    Full Text Available In this study, I focus on the problem of relations between art and theoretical work when they are performed in hypertext/hypermedia Net Art environment. Mark Amerika’s hypermedia practice, produced by digital technologies and focused on the questions of status, functions and modes of art and theory productions in information and biopolitical society, is considered as a case study. Amerika uses hypertext and hypermedia for realization of research art practice and as a media of post-pedagogical and theoretical work which deviate from determined types of scholarly discourses about art and expanding the concept of writing in hypermedia direction. Referring to biopolitical theories, Amerika emphasizes the communication linkage problem between biological organism and networked, hypertextual systems which is always de/regulatory. Remixology, implemented in digital, interactive internet environment, Amerika considers as a critical metaactivity against the manipulation of behavior in mass media of communications space and system of global networking.

  18. Art and Culture in the Space Age

    Science.gov (United States)

    Guidi, A.; de Chiara, V.

    2002-01-01

    The relation between culture and science it is a key point for understanding of our changing world. The relation between Art and Science needs to be analyzed more deeply and some specific field have to be studied with the help of people who really work in these field. One of the selected field will be certainly "theatre" one of the most ancient form of art and especially of communication. Since the Greek culture theatre contributed to diffuse culture, not only in the same community, but even in different one. Actors and their play were always travelling around. With the help of a director and of an actor in the paper will be described the argument from them point of view. Another fundamental art form is "Architecture". There is in the last period a strong changing in this field, the architecture is the form of art which is more related to technology. It can be said that Architecture can be considered as a "bridge" between Art and Technology. Finally even all the visual arts are strongly influenced by the nowadays technology. Different kind of visual arts will be considered, and impressions from people working on them will be analysed. An other aspect of our changing world is the evolution of the communication and the diffusion of culture, through century. This aspect and the nowadays level of "communication technology" is another key point who will be further analyzed. Conclusion is identified in opening the door to a wider variety of experiments on the International Space Station (ISS). A type of experiments devoted to involve a wider number of people in space technology. A type of experiments which will also bring the space age closer to a public that has least interest in technical fields. This increase of public support will bring to the space technology an increase in development. The more public interest there is in a certain technology, the larger it is its development. Finally this type of experiments would also open sociological and psychological study.

  19. Informal Language Learning Setting: Technology or Social Interaction?

    Science.gov (United States)

    Bahrani, Taher; Sim, Tam Shu

    2012-01-01

    Based on the informal language learning theory, language learning can occur outside the classroom setting unconsciously and incidentally through interaction with the native speakers or exposure to authentic language input through technology. However, an EFL context lacks the social interaction which naturally occurs in an ESL context. To explore…

  20. State-of-art technology of fuels for burning minor actinides. An OECD/NEA study

    International Nuclear Information System (INIS)

    Ogawa, Toru; Konings, R.J.M.; Pillon, S.; Schram, R.P.C.; Verwerft, M.; Wallenius, J.

    2005-01-01

    At OECD/NEA, Working Party on Scientific Issues in Partitioning and Transmutation was formed for 2000-2004, which studied the status and trends of scientific issues in Partitioning and Transmutation (P and T). The study included the scientific and technical issues of fuels and materials, which are related to dedicated systems for transmutation. This paper summarizes the state-of-art technology of the fuels for burning minor actinides (neptunium, americium and curium). (author)

  1. Digital Technology and the Interactive Television

    Directory of Open Access Journals (Sweden)

    Ozéias Teixeira de Souza

    2008-08-01

    Full Text Available In this article it is analyzed the impact that the digital technology process causes in the way that television participates of the social life in Brazil. Trying a non-hermeneutic approach, it is proposed to think this new role of television, from the materiality existing on this media that can bring more interactivity and conducts the changes over people behavior. In our opinion, we realize that materiality can support the transposition of the nowadays analogical interaction form – the televiewer-television model – to a user-machine model in the digital television.

  2. THE ISSUE OF FORMING FUTURE MUSIC TEACHERS’ PROFESSIONAL COMPETENCE BY COMPUTER TECHNOLOGY TOOLS IN THE THEORY OF NATIONAL ART

    Directory of Open Access Journals (Sweden)

    Lyudmila Gavrilova

    2017-04-01

    Full Text Available The article deals with theoretical aspects of forming future music teachers’ professional competence by computer technology tools. The concept of professional competence has become a major criterion of preparing students for professional activities. The issue of the article is relevant as the competence approach has become a basis of implementing computer technologies into future music teachers’ training. The authors give a detailed analysis of implementing computer technologies into musical education. The special attention is paid to using a computer in musical education and making electronic pedagogical resources. The aim of the article is to outline the directions of national art research in the process of implementing computer tools that is one of the most efficient ways of updating process of future music teachers’ training. The article reveals theoretical aspects of forming future music teachers’ professional competence by computer technology tools. The authors point out that implementing musical and computer technologies into music art practice is realized in some directions: using a computer as a new musical instrument in composers, sound engineers, and arrangers’ activities; using a computer for studying the quality of music sound, analysing sounds and music compositions, spectral analysis of acoustic characteristics of singers’ voice; studying ancient music manuscripts due to digital technology; developing hardware and software for music education. A distinct direction of research is the pedagogical aspect of using a computer in music education (music and the use of special software for recording and editing music, the use of multimedia to enhance visibility in education, development of e-learning resources, etc.. The authors conclude that implementing computer technologies into future music teachers’ training makes this process more efficient. In the authors’ opinion the widespread introduction of distance learning

  3. Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly.

    Science.gov (United States)

    Chereji, Razvan V; Bharatula, Vasudha; Elfving, Nils; Blomberg, Jeanette; Larsson, Miriam; Morozov, Alexandre V; Broach, James R; Björklund, Stefan

    2017-09-06

    Mediator is a multi-unit molecular complex that plays a key role in transferring signals from transcriptional regulators to RNA polymerase II in eukaryotes. We have combined biochemical purification of the Saccharomyces cerevisiae Mediator from chromatin with chromatin immunoprecipitation in order to reveal Mediator occupancy on DNA genome-wide, and to identify proteins interacting specifically with Mediator on the chromatin template. Tandem mass spectrometry of proteins in immunoprecipitates of mediator complexes revealed specific interactions between Mediator and the RSC, Arp2/Arp3, CPF, CF 1A and Lsm complexes in chromatin. These factors are primarily involved in chromatin remodeling, actin assembly, mRNA 3'-end processing, gene looping and mRNA decay, but they have also been shown to enter the nucleus and participate in Pol II transcription. Moreover, we have found that Mediator, in addition to binding Pol II promoters, occupies chromosomal interacting domain (CID) boundaries and that Mediator in chromatin associates with proteins that have been shown to interact with CID boundaries, such as Sth1, Ssu72 and histone H4. This suggests that Mediator plays a significant role in higher-order genome organization. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. How ordinary judges and juries decide the seemingly complex technological questions of patentability over the prior art.

    Science.gov (United States)

    Kieff, F Scott

    2003-01-01

    Determinations of patentability over the prior art are often thought to raise questions that are so technologically complex that they require special training and judgment to answer, especially in fast-moving fields like modern biotechnology. This essay explores the somewhat counterintuitive argument that under the U.S. system they do not and should not. According to this view, determinations of patentability over the prior art are based entirely on factual inquiries that are best made by lay judges and juries, just like the factual determinations these people regularly make in any ordinary nonpatent trial. This is good because judges and juries are adept at these determinations, and because appellate courts are adept at reviewing them. It leads to a system that is cheaper overall in allowing private litigants to better predict outcomes that also better approximate the correct answer than would be possible under other regimes premised upon the expert technological knowledge and judgment of a decisionmaker.

  5. Art : accessible, renewable technology

    International Nuclear Information System (INIS)

    Middleton, C.D.

    2004-01-01

    This paper focuses on the role of non-governmental organization (NGO) citizen groups in Ontario in the use and production of electricity. NGOs have the potential to act both directly on their own accord, and indirectly by pressuring government and others. Current demand for electricity is divided between industrial, commercial and residential users. Citizens have an important role to play in reducing energy demand. On the supply side, there is a revival of interest in renewable energy based on wind, photovoltaic and local-hydro technologies as a result of the escalating environmental and economic costs of coal and nuclear generation. However, citizen groups have greater interest and enthusiasm than technical expertise, creating a mismatch between technological solutions and human need or use of them. This paper discusses how this mismatch applies to renewable-energy technologies, many of which are not especially user-friendly, or accessible. While alternative technologies are increasingly welcomed by government, industry is developing a large and growing array of technological devices. In between this is the citizen, who, despite keen interest, can be overwhelmed by the complexity of the situation. This paper links the theoretical perspective to the real world with a discussion of the dynamics between people and renewable energy in citizen groups and makes particular reference to one group, Citizens for Renewable Energy, that has been making renewable energy technology more accessible to its members for over a decade

  6. THE SPECIFICS OF ART INFORMATION AND COMMUNICATION IN ART CLASSES

    Directory of Open Access Journals (Sweden)

    Maja Hrvanović

    2013-09-01

    Full Text Available In this study, the author puts forward the hypothesis that the representation of information of artistic type in art classes affects the formation of judgement of taste as one of the most important factors for intensifying and memorising the experience of artistic content. The function of art education is to enable an individual to „read“ the work of art, to supply him with skills and knowledge necessary to recognise formally significant determinants in art. Creation of new conceptual design, functional usage of visual information in communication process, individuality in shaping their own criteria, are just some of the determinants of artistic development. Art education accorded with development of technology and visual communication is necessary for human development of young individuals and improvement of their general level of culture. Conceptually – concrete art can uncritically be understood as direct and „comprehensible“. The observer with basic artistic education has no difficulties in expressing judgement about realistic work of art, because all mental functions, by analogy, occur with the experience. Art formed in the area of symbolic self-expression, areal structure, requires special knowledge and skills to overcome sensed and decorative levels when experiencing a work of art. The classes of art education should teach the students the methods of judging the artistic quality, to significantly influence their ability of critical analysis, interpretation and formation of judgement of taste

  7. Attractive PHHP interactions revealed by state-of-the-art ab initio calculations.

    Science.gov (United States)

    Yourdkhani, Sirous; Jabłoński, Mirosław; Echeverría, Jorge

    2017-10-25

    We report in this work a combined structural and state-of-the-art computational study of homopolar P-HH-P intermolecular contacts. Database surveys have shown the abundance of such surprisingly unexplored contacts, which are usually accompanied by other weak interactions in the solid state. By means of a detailed theoretical study utilizing SAPT(DFT), MP2, SCS-MP2, MP2C and CCSD(T) methods and both aug-cc-pVXZ and aug-cc-pCVXZ (X = D, T, Q, 5) basis sets as well as extrapolation to the CBS limit, we have shown that P-HH-P contacts are indeed attractive and considerably strong. SAPT(DFT) calculations have revealed the dispersive nature of the P-HH-P interaction with only minor contribution of the inductive term, whereas the first-order electrostatic term is clearly overbalanced by the first-order exchange energy. In general the computed interaction energies follow the trend: E ≈ E < E < E. Our results have also shown that the aug-cc-pVDZ (or aug-cc-pCVDZ) basis set is not yet well balanced and that the second-order dispersion energy term is the slowest converging among all SAPT(DFT) energy components. Compared to aug-cc-pVXZ basis sets, their core-correlation counterparts have a modest influence on all supermolecular interaction energies and a negligible influence on both the SAPT(DFT) interaction energy and its components.

  8. Constraining flavor changing interactions from LHC Run-2 dilepton bounds with vector mediators

    Directory of Open Access Journals (Sweden)

    Farinaldo S. Queiroz

    2016-12-01

    Full Text Available Within the context of vector mediators, is a new signal observed in flavor changing interactions, particularly in the neutral mesons systems K0−K¯0, D0−D¯0 and B0−B0¯, consistent with dilepton resonance searches at the LHC? In the attempt to address this very simple question, we discuss the complementarity between flavor changing neutral current (FCNC and dilepton resonance searches at the LHC run 2 at 13 TeV with 3.2 fb−1 of integrated luminosity, in the context of vector mediators at tree level. Vector mediators, are often studied in the flavor changing framework, specially in the light of the recent LHCb anomaly observed at the rare B decay. However, the existence of stringent dilepton bound severely constrains flavor changing interactions, due to restrictive limits on the Z′ mass. We discuss this interplay explicitly in the well motivated framework of a 3-3-1 scheme, where fermions and scalars are arranged in the fundamental representation of the weak SU(3 gauge group. Due to the paucity of relevant parameters, we conclude that dilepton data leave little room for a possible new physics signal stemming from these systems, unless a very peculiar texture parametrization is used in the diagonalization of the CKM matrix. In other words, if a signal is observed in such flavor changing interactions, it unlikely comes from a 3-3-1 model.

  9. Remote and continuous gamma spectrometry for environmental radiation protection: state of the art technology and perspectives

    International Nuclear Information System (INIS)

    Van Put, Ph.; Lellis, C.; Debauche, A.; Lacroix, J-P.

    2004-01-01

    The instruments technologies for radiological protection of the environment have been considerably enhanced since the last 20 years. From very simple warning bells in the early 80s, the instruments have been sophisticated nowadays to a degree where their performances can be compared to the performances achieved in low level laboratories. This presentation will briefly overview the evolution of these instruments by comparing their technology, their methodology and their performances. Next, it will present the concepts of the state of the art technology in the field of continuous monitoring of the environment. A discussion will follow on the performances and the limitations of this technology. Finally, the presentation will highlight the future perspective of developments by taking into account recent progress in the field of radiation detectors, telecommunication and computer sciences among others. (authors)

  10. Toehold-mediated internal control to probe the near-field interaction between the metallic nanoparticle and the fluorophore

    Science.gov (United States)

    Ang, Y. S.; Yung, L. Y. L.

    2014-10-01

    Metallic nanoparticles (MNPs) are known to alter the emission of vicinal fluorophores through the near-field interaction, leading to either fluorescence quenching or enhancement. Much ambiguity remains in the experimental outcome of such a near-field interaction, particularly for bulk colloidal solution. It is hypothesized that the strong far-field interference from the inner filter effect of the MNPs could mask the true near-field MNP-fluorophore interaction significantly. Thus, in this work, a reliable internal control capable of decoupling the near-field interaction from far-field interference is established by the use of the DNA toehold concept to mediate the in situ assembly and disassembly of the MNP-fluorophore conjugate. A model gold nanoparticle (AuNP)-Cy3 system is used to investigate our proposed toehold-mediated internal control system. The maximum fluorescence enhancement is obtained for large-sized AuNP (58 nm) separated from Cy3 at an intermediate distance of 6.8 nm, while fluorescence quenching is observed for smaller-sized AuNP (11 nm and 23 nm), which is in agreement with the theoretical values reported in the literature. This work shows that the toehold-mediated internal control design can serve as a central system for evaluating the near-field interaction of other MNP-fluorophore combinations and facilitate the rational design of specific MNP-fluorophore systems for various applications.Metallic nanoparticles (MNPs) are known to alter the emission of vicinal fluorophores through the near-field interaction, leading to either fluorescence quenching or enhancement. Much ambiguity remains in the experimental outcome of such a near-field interaction, particularly for bulk colloidal solution. It is hypothesized that the strong far-field interference from the inner filter effect of the MNPs could mask the true near-field MNP-fluorophore interaction significantly. Thus, in this work, a reliable internal control capable of decoupling the near

  11. Young Pianists Exploring Improvisation Using Interactive Music Technology

    Science.gov (United States)

    Rowe, Victoria; Triantafyllaki, Angeliki; Anagnostopoulou, Xristina

    2015-01-01

    The use of music technology in the enhancement of young pianists' musical improvisations has been scarcely explored in instrumental music teaching and learning research. In the present study, 19 piano pupils aged 6-10 from the UK and Greece used an interactive improvisation system called Musical Interaction Relying On Reflexion (MIROR)-Impro for…

  12. Robot-assisted gait training for stroke patients: current state of the art and perspectives of robotics.

    Science.gov (United States)

    Morone, Giovanni; Paolucci, Stefano; Cherubini, Andrea; De Angelis, Domenico; Venturiero, Vincenzo; Coiro, Paola; Iosa, Marco

    2017-01-01

    In this review, we give a brief outline of robot-mediated gait training for stroke patients, as an important emerging field in rehabilitation. Technological innovations are allowing rehabilitation to move toward more integrated processes, with improved efficiency and less long-term impairments. In particular, robot-mediated neurorehabilitation is a rapidly advancing field, which uses robotic systems to define new methods for treating neurological injuries, especially stroke. The use of robots in gait training can enhance rehabilitation, but it needs to be used according to well-defined neuroscientific principles. The field of robot-mediated neurorehabilitation brings challenges to both bioengineering and clinical practice. This article reviews the state of the art (including commercially available systems) and perspectives of robotics in poststroke rehabilitation for walking recovery. A critical revision, including the problems at stake regarding robotic clinical use, is also presented.

  13. Hopi and Anasazi Alignments and Rock Art

    Science.gov (United States)

    Bates, Bryan C.

    The interaction of light and shadow on ancestral Puebloan rock art, or rock art demarcating sunrise/set horizon points that align with culturally significant dates, has long been assumed to be evidence of "intentional construct" for marking time or event by the native creator. However, anthropological rock art research requires the scientific control of cultural time, element orientation and placement, structure, and association with other rock art elements. The evaluation of five exemplars challenges the oft-held assumption that "if the interaction occurs, it therefore supports intentional construct" and thereby conveys meaning to the native culture.

  14. Intercultural and Media Education on Art Classes

    Science.gov (United States)

    Borges, Maria José; Chaves, Anabela; Costa, Manuela; Pereira, Emília Sá

    2009-01-01

    Visual art, music and literature, are part of the culture. Thus Art shows the interactions between different cultures. The aim of the article is to present some activities to include intercultural issues in Art and Mother Language classes. Art classes also give the opportunity to do Media Education.

  15. VISUAL ARTS AS THE FIELD OF KNOWLEDGE IN ARTE NA ESCOLA - DAC / UFSC PROJECT

    Directory of Open Access Journals (Sweden)

    Richard Perassi Luiz de Sousa

    2011-07-01

    Full Text Available This paper presents and justifies the content worked in the extension course "The Visual Arts as a field of knowledge," which was sponsored by the Departamento Artístico Cultural – DAC/ UFSC, within the project "Arte na Escola". The course was directed at teachers of Art and also received other stakeholders in the study of Visual Arts, focusing on contemporary art. Art is justified as a field of knowledge in that, throughout its history, many have been developed knowledge, technologies and expertise applied to the development of artistic activities. In addition, each work of art represents a unique and innovative testimony of their time and offers a new set of knowledge, which broadens the cultural heritage of humanity. Finally, knowledge and artistic products are also applied in developing other areas of knowledge.

  16. Azadirachtin interacts with retinoic acid receptors and inhibits retinoic acid-mediated biological responses.

    Science.gov (United States)

    Thoh, Maikho; Babajan, Banaganapalli; Raghavendra, Pongali B; Sureshkumar, Chitta; Manna, Sunil K

    2011-02-11

    Considering the role of retinoids in regulation of more than 500 genes involved in cell cycle and growth arrest, a detailed understanding of the mechanism and its regulation is useful for therapy. The extract of the medicinal plant Neem (Azadirachta indica) is used against several ailments especially for anti-inflammatory, anti-itching, spermicidal, anticancer, and insecticidal activities. In this report we prove the detailed mechanism on the regulation of retinoic acid-mediated cell signaling by azadirachtin, active components of neem extract. Azadirachtin repressed all trans-retinoic acid (ATRA)-mediated nuclear transcription factor κB (NF-κB) activation, not the DNA binding but the NF-κB-dependent gene expression. It did not inhibit IκBα degradation, IκBα kinase activity, or p65 phosphorylation and its nuclear translocation but inhibited NF-κB-dependent reporter gene expression. Azadirachtin inhibited TRAF6-mediated, but not TRAF2-mediated NF-κB activation. It inhibited ATRA-induced Sp1 and CREB (cAMP-response element-binding protein) DNA binding. Azadirachtin inhibited ATRA binding with retinoid receptors, which is supported by biochemical and in silico evidences. Azadirachtin showed strong interaction with retinoid receptors. It suppressed ATRA-mediated removal of retinoid receptors, bound with DNA by inhibiting ATRA binding to its receptors. Overall, our data suggest that azadirachtin interacts with retinoic acid receptors and suppresses ATRA binding, inhibits falling off the receptors, and activates transcription factors like CREB, Sp1, NF-κB, etc. Thus, azadirachtin exerts anti-inflammatory and anti-metastatic responses by a novel pathway that would be beneficial for further anti-inflammatory and anti-cancer therapies.

  17. Azadirachtin Interacts with Retinoic Acid Receptors and Inhibits Retinoic Acid-mediated Biological Responses*

    Science.gov (United States)

    Thoh, Maikho; Babajan, Banaganapalli; Raghavendra, Pongali B.; Sureshkumar, Chitta; Manna, Sunil K.

    2011-01-01

    Considering the role of retinoids in regulation of more than 500 genes involved in cell cycle and growth arrest, a detailed understanding of the mechanism and its regulation is useful for therapy. The extract of the medicinal plant Neem (Azadirachta indica) is used against several ailments especially for anti-inflammatory, anti-itching, spermicidal, anticancer, and insecticidal activities. In this report we prove the detailed mechanism on the regulation of retinoic acid-mediated cell signaling by azadirachtin, active components of neem extract. Azadirachtin repressed all trans-retinoic acid (ATRA)-mediated nuclear transcription factor κB (NF-κB) activation, not the DNA binding but the NF-κB-dependent gene expression. It did not inhibit IκBα degradation, IκBα kinase activity, or p65 phosphorylation and its nuclear translocation but inhibited NF-κB-dependent reporter gene expression. Azadirachtin inhibited TRAF6-mediated, but not TRAF2-mediated NF-κB activation. It inhibited ATRA-induced Sp1 and CREB (cAMP-response element-binding protein) DNA binding. Azadirachtin inhibited ATRA binding with retinoid receptors, which is supported by biochemical and in silico evidences. Azadirachtin showed strong interaction with retinoid receptors. It suppressed ATRA-mediated removal of retinoid receptors, bound with DNA by inhibiting ATRA binding to its receptors. Overall, our data suggest that azadirachtin interacts with retinoic acid receptors and suppresses ATRA binding, inhibits falling off the receptors, and activates transcription factors like CREB, Sp1, NF-κB, etc. Thus, azadirachtin exerts anti-inflammatory and anti-metastatic responses by a novel pathway that would be beneficial for further anti-inflammatory and anti-cancer therapies. PMID:21127062

  18. Sound Art Situations

    DEFF Research Database (Denmark)

    Krogh Groth, Sanne; Samson, Kristine

    2017-01-01

    and combine theories from several fields. Aspects of sound art studies, performance studies and contemporary art studies are presented in order to theoretically explore the very diverse dimensions of the two sound art pieces: Visual, auditory, performative, social, spatial and durational dimensions become......This article is an analysis of two sound art performances that took place June 2015 in outdoor public spaces in the social housing area Urbanplanen in Copenhagen, Denmark. The two performances were On the production of a poor acoustics by Brandon LaBelle and Green Interactive Biofeedback...... Environments (GIBE) by Jeremy Woodruff. In order to investigate the complex situation that arises when sound art is staged in such contexts, the authors of this article suggest exploring the events through approaching them as ‘situations’ (Doherty 2009). With this approach it becomes possible to engage...

  19. Plant-Mediated Systemic Interactions Between Pathogens, Parasitic Nematodes, and Herbivores Above- and Belowground

    NARCIS (Netherlands)

    Biere, A.; Goverse, A.

    2016-01-01

    Plants are important mediators of interactions between aboveground (AG) and belowground (BG) pathogens, arthropod herbivores, and nematodes (phytophages). We highlight recent progress in our understanding of within- and cross-compartment plant responses to these groups of phytophages in terms of

  20. Plant-mediated systemic interactions between pathogens, parasitic nematodes, and herbivores above- and belowground

    NARCIS (Netherlands)

    Biere, A.; Goverse, Aska

    2016-01-01

    Plants are important mediators of interactions between aboveground (AG) and belowground (BG) pathogens, arthropod herbivores, and nematodes (phytophages). We highlight recent progress in our understanding of within and cross-compartment plant responses to these groups of phytophages in terms of

  1. Exploring How Technology Mediates the Types of Relationships Formed in Sociotechnical Systems

    Science.gov (United States)

    Chu, Kar-Hai

    2012-01-01

    This work presents an exploratory study of how technology mediates the different types of relationships that are formed in sociotechnical systems. More people each day are connecting with each other through social networks, online communities, and other forms of virtual environments. Whether for education, information seeking, friendship,…

  2. Wolfram technologies as an integrated scalable platform for interactive learning

    Science.gov (United States)

    Kaurov, Vitaliy

    2012-02-01

    We rely on technology profoundly with the prospect of even greater integration in the future. Well known challenges in education are a technology-inadequate curriculum and many software platforms that are difficult to scale or interconnect. We'll review an integrated technology, much of it free, that addresses these issues for individuals and small schools as well as for universities. Topics include: Mathematica, a programming environment that offers a diverse range of functionality; natural language programming for getting started quickly and accessing data from Wolfram|Alpha; quick and easy construction of interactive courseware and scientific applications; partnering with publishers to create interactive e-textbooks; course assistant apps for mobile platforms; the computable document format (CDF); teacher-student and student-student collaboration on interactive projects and web publishing at the Wolfram Demonstrations site.

  3. Shadow art

    KAUST Repository

    Mitra, Niloy J.

    2009-01-01

    "To them, I said, the truth would be literally nothing but the shadows of the images." - Plato, The Republic Shadow art is a unique form of sculptural art where the 2D shadows cast by a 3D sculpture are essential for the artistic effect. We introduce computational tools for the creation of shadow art and propose a design process where the user can directly specify the desired shadows by providing a set of binary images and corresponding projection information. Since multiple shadow images often contradict each other, we present a geometric optimization that computes a 3D shadow volume whose shadows best approximate the provided input images. Our analysis shows that this optimization is essential for obtaining physically realizable 3D sculptures. The resulting shadow volume can then be modified with a set of interactive editing tools that automatically respect the often intricate shadow constraints. We demonstrate the potential of our system with a number of complex 3D shadow art sculptures that go beyond what is seen in contemporary art pieces. © 2009 ACM.

  4. Panel session on the state of the art in nuclear reactor technology

    International Nuclear Information System (INIS)

    Roche, R.

    1977-01-01

    The state of the art in the technology of pressure vessels and piping of the primary cooling circuit of nuclear steam supply systems is discussed. Design and analysis are considered in the frame of the two types of nuclear reactor retained in France (PWR and the pool type LMFBR). Designing nuclear pressure vessels asks for some more specific Codes and Standards than for conventional vessels, and the stress analysis complementing by a direct comparison between operating loads and failure loads is a mandatory practice in France. As for pool type LMFBR, the structural problems of the nuclear vessel are essentially due to component shape, small thickness, and large stress range

  5. Audio Technology and Mobile Human Computer Interaction

    DEFF Research Database (Denmark)

    Chamberlain, Alan; Bødker, Mads; Hazzard, Adrian

    2017-01-01

    Audio-based mobile technology is opening up a range of new interactive possibilities. This paper brings some of those possibilities to light by offering a range of perspectives based in this area. It is not only the technical systems that are developing, but novel approaches to the design...... and understanding of audio-based mobile systems are evolving to offer new perspectives on interaction and design and support such systems to be applied in areas, such as the humanities....

  6. Learning Opportunities in Synchronous Computer-Mediated Communication and Face-to-Face Interaction

    Science.gov (United States)

    Kim, Hye Yeong

    2014-01-01

    This study investigated how synchronous computer-mediated communication (SCMC) and face-to-face (F2F) oral interaction influence the way in which learners collaborate in language learning and how they solve their communicative problems. The findings suggest that output modality may affect how learners produce language, attend to linguistic forms,…

  7. Art and architecture as experience: an alternative approach to bridging art history and the neurosciences.

    Science.gov (United States)

    Zschocke, Nina

    2012-08-01

    In 1972, Michael Baxandal characterizes the processes responsible for the cultural relativism of art experience as highly complex and unknown in their physiological detail. While art history still shows considerable interest in the brain sciences forty years later, most cross-disciplinary studies today are referring to the neurosciences in an attempt to seek scientific legitimization of variations of a generalized and largely deterministic model of perception, reducing interaction between a work of art and its observers to a set of biological automatisms. I will challenge such an approach and take up art theory's interest in the historico-cultural and situational dimensions of art experience. Looking at two examples of large-scale installation and sculptural post-war American art, I will explore instable perceptions of depth and changing experiences of space that indicate complex interactions between perceptual and higher cognitive processes. The argument will draw on recent theories describing neuronal processes underlying multistable phenomena, eye movement, visual attention and decision-making. As I will show a large number of neuroscientific studies provide theoretical models that help us analyse not the anthropological constants but the influence of cultural, individual and situational variables on aesthetic experience.

  8. State of the art magnetic resonance imaging

    International Nuclear Information System (INIS)

    Weissman, J.D.

    1987-01-01

    In less than a decade Magnetic Resonance Imaging (MRI) has evolved from a laboratory demonstration to a safe and effective technique for clinical diagnosis. This evolutionary process continues. At this time 2-D and 3-D imaging of the head and body is firmly established in clinical use. Surface coil imaging, two-component chemical shift imaging, in-vivo spectroscopy and flow imaging are currently in various stages of development. The present state of the art of MRI is a function of an array of technologies: magnet, Rf coil, Rf pulse amplifier, gradient coil and driver, pulse programmer, A/D converter, computer system architecture, array processors and mass storage (both magnetic and optical). The overall product design is the result of a complex process which balances the advantages and disadvantages of each component for optimal system performance and flexibility. The author discusses the organization of a state-of-the-art MRI system. Several examples of the kinds of system interactions affecting design choices are given. (Auth.)

  9. How do patients actually experience and use art in hospitals? The significance of interaction: a user-oriented experimental case study

    OpenAIRE

    Nielsen, Stine L.; Fich, Lars B.; Roessler, Kirsten K.; Mullins, Michael F.

    2017-01-01

    ABSTRACT This article aims to understand patient wellbeing and satisfaction and to qualify the current guidelines for the application of art in hospitals. Employing anthropological methods, we focus on the interactional aspects of art in health interventions. A user-oriented study ranked 20 paintings, followed by an experiment using paintings in the dayroom of five medical wards. Fieldwork was done over a two-week period. During the first week, dayrooms were configured without the presence of...

  10. Two pion mediated scalar isoscalar NN interaction in the nuclear medium

    International Nuclear Information System (INIS)

    Kaskulov, Murat M.; Oset, E.; Vacas, M.J. Vicente

    2006-01-01

    We study the modification of the nucleon-nucleon interaction in a nuclear medium in the scalar isoscalar channel, mediated by the exchange of two correlated (σ channel) or uncorrelated pions. For this purpose we use a standard approach for the renormalization of pions in nuclei. The corrections obtained for the NN interaction in the medium in this channel are of the order of 20% of the free one in average, and the consideration of short-range correlations plays an important role in providing these moderate changes. Yet, the corrections are sizable enough to suggest further studies of the stability and properties of nuclear matter

  11. 3D technology in fine art and craft exploring 3D printing, scanning, sculpting and milling

    CERN Document Server

    Mongeon, Bridgette

    2015-01-01

    The possibilities for creation are endless with 3D printing, sculpting, scanning, and milling, and new opportunities are popping up faster than artists can keep up with them. 3D Technology in Fine Art and Craft takes the mystery out of these exciting new processes by demonstrating how to navigate their digital components and showing their real world applications. Artists will learn to incorporate these new technologies into their studio work and see their creations come to life in a physical form never before possible. Featuring a primer on 3D basics for beginners,interviews, tutorials, and ar

  12. Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

    Science.gov (United States)

    Luisier, Raphaëlle; Unterberger, Elif B.; Goodman, Jay I.; Schwarz, Michael; Moggs, Jonathan; Terranova, Rémi; van Nimwegen, Erik

    2014-01-01

    Gene regulatory interactions underlying the early stages of non-genotoxic carcinogenesis are poorly understood. Here, we have identified key candidate regulators of phenobarbital (PB)-mediated mouse liver tumorigenesis, a well-characterized model of non-genotoxic carcinogenesis, by applying a new computational modeling approach to a comprehensive collection of in vivo gene expression studies. We have combined our previously developed motif activity response analysis (MARA), which models gene expression patterns in terms of computationally predicted transcription factor binding sites with singular value decomposition (SVD) of the inferred motif activities, to disentangle the roles that different transcriptional regulators play in specific biological pathways of tumor promotion. Furthermore, transgenic mouse models enabled us to identify which of these regulatory activities was downstream of constitutive androstane receptor and β-catenin signaling, both crucial components of PB-mediated liver tumorigenesis. We propose novel roles for E2F and ZFP161 in PB-mediated hepatocyte proliferation and suggest that PB-mediated suppression of ESR1 activity contributes to the development of a tumor-prone environment. Our study shows that combining MARA with SVD allows for automated identification of independent transcription regulatory programs within a complex in vivo tissue environment and provides novel mechanistic insights into PB-mediated hepatocarcinogenesis. PMID:24464994

  13. A State-of-the-Art Survey of Indoor Positioning and Navigation Systems and Technologies

    Directory of Open Access Journals (Sweden)

    Wilson Sakpere

    2017-12-01

    Full Text Available The research and use of positioning and navigation technologies outdoors has seen a steady and exponential growth. Based on this success, there have been attempts to implement these technologies indoors, leading to numerous studies. Most of the algorithms, techniques and technologies used have been implemented outdoors. However, how they fare indoors is different altogether. Thus, several technologies have been proposed and implemented to improve positioning and navigation indoors. Among them are Infrared (IR, Ultrasound, Audible Sound, Magnetic, Optical and Vision, Radio Frequency (RF, Visible Light, Pedestrian Dead Reckoning (PDR/Inertial Navigation System (INS and Hybrid. The RF technologies include Bluetooth, Ultra-wideband (UWB, Wireless Sensor Network (WSN, Wireless Local Area Network (WLAN, Radio-Frequency Identification (RFID and Near Field Communication (NFC. In addition, positioning techniques applied in indoor positioning systems include the signal properties and positioning algorithms. The prevalent signal properties are Angle of Arrival (AOA, Time of Arrival (TOA, Time Difference of Arrival (TDOA and Received Signal Strength Indication (RSSI, while the positioning algorithms are Triangulation, Trilateration, Proximity and Scene Analysis/ Fingerprinting. This paper presents a state-of-the-art survey of indoor positioning and navigation systems and technologies, and their use in various scenarios. It analyses distinct positioning technology metrics such as accuracy, complexity, cost, privacy, scalability and usability. This paper has profound implications for future studies of positioning and navigation.

  14. Erica the Rhino: A Case Study in Using Raspberry Pi Single Board Computers for Interactive Art

    Directory of Open Access Journals (Sweden)

    Philip J. Basford

    2016-06-01

    Full Text Available Erica the Rhino is an interactive art exhibit created by the University of Southampton, UK. Erica was created as part of a city wide art trail in 2013 called “Go! Rhinos”, curated by Marwell Wildlife, to raise awareness of Rhino conservation. Erica arrived as a white fibreglass shell which was then painted and equipped with five Raspberry Pi Single Board Computers (SBC. These computers allowed the audience to interact with Erica through a range of sensors and actuators. In particular, the audience could feed and stroke her to prompt reactions, as well as send her Tweets to change her behaviour. Pi SBCs were chosen because of their ready availability and their educational pedigree. During the deployment, ‘coding clubs’ were run in the shopping centre where Erica was located, and these allowed children to experiment with and program the same components used in Erica. The experience gained through numerous deployments around the country has enabled Erica to be upgraded to increase reliability and ease of maintenance, whilst the release of the Pi 2 has allowed her responsiveness to be improved.

  15. Ethically sound technology? Guidelines for interactive ethical assessment of personal health monitoring.

    Science.gov (United States)

    Palm, Elin; Nordgren, Anders; Verweij, Marcel; Collste, Göran

    2013-01-01

    Novel care-technologies possess a transformational potential. Future care and support may be provided via monitoring technologies such as smart devices, sensors, actors (robots) and Information and Communication Technologies. Such technologies enable care provision outside traditional care institutions, for instance in the homes of patients. Health monitoring may become "personalized" i.e. tailored to the needs of individual care recipients' but may also alter relations between care providers and care recipents, shape and form the care environment and influence values central to health-care. Starting out from a social constructivist theory of technology, an interactive ethical assessment-model is offered. The suggested model supplements a traditional analysis based on normative ethical theory (top-down approach) with interviews including relevant stakeholders (a bottom-up approach). This method has been piloted by small-scale interviews encircling stakeholder perspectives on three emerging technologies: (1) Careousel, a smart medicine-management device, (2) Robot Giraff, an interactive and mobile communication-device and (3) I-Care, a care-software that combines alarm and register system. By incorporating stakeholder perspectives into the analysis, the interactive ethical assessment model provides a richer understanding of the impact of PHM-technologies on ethical values than a traditional top-down model. If the assessment is conducted before the technology has reached the market - preferably in close interaction with developers and users - ethically sound technologies may be obtained.

  16. Air pollution control technologies and their interactions

    Energy Technology Data Exchange (ETDEWEB)

    Nalbandian, H. [IEA Clean Coal Centre, London (United Kingdom)

    2004-11-01

    A large number of coal-fired power stations have been fitted/retrofitted with dedicated air pollutant control technologies. Experience shows that these technologies can have complex interactions and can impact each other as well as balance of plant, positively and/or negatively. Particulate matter (PM) is usually captured with electrostatic precipitators (ESPs) and fabric filters (FF). These technologies are efficient and reliable but their performance may be affected by modifying operating conditions and introducing primary measures for NOx reduction. Flue gas desulphurisation (FGD) systems for SO{sub 2} control have been installed in many facilities with the most popular technology being the wet limestone/gypsum scrubber. FGD use can decrease particulate matter and mercury emissions which is a major issue in the USA, cause an increase in carbon dioxide emissions, and in solids by-product. Primary measures such as low NOx burners (LNBs) and overfire air (OFA) minimise NOx formation but can increase carbon in ash (CIA) which can cause problems with fly ash sales but may also improve mercury capture. Reducing NOx emissions with selective catalytic reduction (SCR) can result in a decrease in particulate matter, an increase in SO{sub 3} emissions and trace increase in NH{sub 3}. This can cause fouling and loss of performance of the air preheater, due to the formation of ammonium sulphates. One way of alleviating this is improved soot-blowing and other cleaning capabilities. This report studies these and other interactions between existing air pollution control technologies in pulverised coal fired power plants. 249 refs., 13 figs., 18 tabs.

  17. Seasonal and scale-dependent variability in nutrient- and allelopathy-mediated macrophyte–phytoplankton interactions

    Directory of Open Access Journals (Sweden)

    Lombardo P.

    2013-08-01

    Full Text Available macrophyte–phytoplankton interactions were investigated using a dual laboratory and field approach during a growing season, with responses quantified as changes in biomass. Short-term, close-range interactions in laboratory microcosms always led to mutual exclusion of macrophytes (Elodea canadensis or Ceratophyllum demersum and algae (Raphidocelis subcapitata, Fistulifera pelliculosa or cyanobacteria (Synechococcus leopoliensis, suggesting regulation by positive feedback mechanisms, progressively establishing and reinforcing a “stable state”. Laboratory results suggest that close-range regulation of R. subcapitata and F. pelliculosa by macrophytes was primarily via nutrient (N, P mediation. Sprig-produced allelochemicals may have contributed to inhibition of S. leopoliensis in C. demersum presence, while S. leopoliensis was apparently enhanced by nutrients leaked by subhealthy (discolored leaves; biomass loss E. canadensis. Seasonal changes in algal growth suppression were correlated with sprig growth. Marginal differences in in situ phytoplankton patterns inside and outside monospecific macrophyte stands suggest that the nutrient- and/or allelopathy-mediated close-range mechanisms observed in the laboratory did not propagate at the macrophyte-stand scale. Factors operating at a larger scale (e.g., lake trophic state, extent of submerged vegetation coverage appear to override in situ macrophyte–phytoplankton close-range interactions.

  18. Social Skills as a Mediator between Anxiety Symptoms and Peer Interactions among Children and Adolescents

    Science.gov (United States)

    Motoca, Luci M.; Williams, Sandra; Silverman, Wendy K.

    2012-01-01

    Objective The present study used a cross-sectional design to examine the relations among youth anxiety symptoms, positive and negative peer interactions, and social skills. Also examined was the mediating role of social skills in the relations between youth anxiety symptoms and positive and negative peer interactions. Youth sex and age were examined as moderators. Method The sample consisted of 397 children and adolescents (M = 10.11 years; 53.4% boys; 74.8% Hispanic Latino) referred to an anxiety disorders clinic. Anxiety symptoms, positive and negative peer interactions, and social skills were assessed using youth and parent ratings. Results Structural equation modeling results indicated that for youth ratings only, youth anxiety symptoms were negatively related to positive peer interactions controlling for primary social phobia and comorbid depressive disorders. For both youth and parent ratings, youth anxiety symptoms were positively related to negative peer interactions and negatively related to social skills. Also for both youth and parent ratings, social skills mediated the relations between youth anxiety symptoms and positive and negative peer interactions. For parent ratings only, the effects of youth anxiety symptoms and social skills on peer interactions were significantly moderated by youth age. Youth sex was not a significant moderator using youth and parent ratings. Conclusions Findings suggest difficulties with social skills and peer interactions are problematic features of youth referred for anxiety problems. Findings highlight the need to improve understanding of anxiety symptoms, social skills, and peer interactions in this population. PMID:22471319

  19. Social skills as a mediator between anxiety symptoms and peer interactions among children and adolescents.

    Science.gov (United States)

    Motoca, Luci M; Williams, Sandra; Silverman, Wendy K

    2012-01-01

    The present study used a cross-sectional design to examine the relations among youth anxiety symptoms, positive and negative peer interactions, and social skills. Also examined was the mediating role of social skills in the relations between youth anxiety symptoms and positive and negative peer interactions. Youth sex and age were examined as moderators. The sample consisted of 397 children and adolescents (M = 10.11 years; 53.4% boys; 74.8% Hispanic Latino) referred to an anxiety disorders clinic. Anxiety symptoms, positive and negative peer interactions, and social skills were assessed using youth and parent ratings. Structural equation modeling results indicated that for youth ratings only, youth anxiety symptoms were negatively related to positive peer interactions controlling for primary social phobia and comorbid depressive disorders. For both youth and parent ratings, youth anxiety symptoms were positively related to negative peer interactions and negatively related to social skills. Also for both youth and parent ratings, social skills mediated the relations between youth anxiety symptoms and positive and negative peer interactions. For parent ratings only, the effects of youth anxiety symptoms and social skills on peer interactions were significantly moderated by youth age. Youth sex was not a significant moderator using youth and parent ratings. Findings suggest that difficulties with social skills and peer interactions are problematic features of youth referred for anxiety problems. Findings highlight the need to improve understanding of anxiety symptoms, social skills, and peer interactions in this population.

  20. Psychiatric disorders among women and men in assisted reproductive technology (ART) treatment. The Danish National ART-Couple (DANAC) cohort

    DEFF Research Database (Denmark)

    Schmidt, Lone; Hageman, Ida; Hougaard, Charlotte Ørsted

    2013-01-01

    -matched population-based cohort of couples with no history of ART treatment. Furthermore, the objective is to study the reproductive outcome of ART treatment among women who have a registered diagnosis of a mental disorder or have used medication for mental disorders prior to ART treatment compared with women in ART...

  1. Tests of fundamental symmetries and interactions - using nuclei and lasers

    NARCIS (Netherlands)

    Jungmann, Klaus Peter

    State of the art laser technology and modern spectroscopic methods allow to address issues of fundamental symmetries and fundamental interactions in atoms with high precision experiments. In particular the discrete symmetries Parity (P), Charge Conjugation (C), Time Reversal (T) as well as their

  2. From Mediatized Emotion to Digital Affect Cultures: New Technologies and Global Flows of Emotion

    OpenAIRE

    Katrin Döveling; Anu A. Harju; Denise Sommer

    2018-01-01

    Research on the processes of mediatization aims to explore the mutual shaping of media and social life and how new media technologies influence and infiltrate social practices and cultural life. We extend this discussion of media’s role in transforming the everyday by including in the discussion the mediatization of emotion and discuss what we conceptualize as digital affect culture(s). We understand these as relational, contextual, globally emergent spaces in the digital environment where af...

  3. Mn(ii) mediated degradation of artemisinin based on Fe3O4@MnSiO3-FA nanospheres for cancer therapy in vivo

    Science.gov (United States)

    Chen, Jian; Zhang, Weijie; Zhang, Min; Guo, Zhen; Wang, Haibao; He, Mengni; Xu, Pengping; Zhou, Jiajia; Liu, Zhenbang; Chen, Qianwang

    2015-07-01

    Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe2+ mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn2+ could substitute for Fe2+ to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hydrophobic ART into tumors in mice models. Mn2+ was released in acidic tumor environments and intracellular lysosomes, interacting with ART to kill cancer cells. The ART-loaded nanocarriers could suppress tumor growth more efficiently than free ART, which could be further illustrated by magnetic resonance imaging (MRI). Histological analysis revealed that the drug delivery system had no obvious effect on the major organs of mice. ART has been reported to have lower toxicity than chemotherapeutics. The ART-loaded nanocarriers are promising to be used in improving the survival of chemotherapy patients, providing a novel method for clinical tumor therapy.Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe2+ mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn2+ could substitute for Fe2+ to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hydrophobic ART into tumors in mice models. Mn2+ was released in acidic tumor environments and intracellular lysosomes, interacting with ART to kill cancer cells. The ART-loaded nanocarriers could suppress tumor growth more efficiently than free ART, which could be further illustrated by magnetic resonance imaging (MRI). Histological analysis revealed that the drug delivery system had no obvious effect on the major organs of mice. ART has been reported to have lower toxicity than chemotherapeutics. The ART-loaded nanocarriers are promising to be used in

  4. The Influence of Interactive Multimedia Technology to Enhance Achievement Students on Practice Skills in Mechanical Technology

    Science.gov (United States)

    Made Rajendra, I.; Made Sudana, I.

    2018-01-01

    Interactive multimedia technology empowers the educational process by means of increased interaction between teachers and the students. The utilization of technology in the instructional media development has an important role in the increase of the quality of teaching and learning achievements of students. The application of multimedia technology in the instructional media development is able to integrate aspects of knowledge and skills. The success of multimedia technology has revolutionized teaching and learning methods. The design of the study was quasi-experimental with pre and post. The instrument used is the form of questionnaires and tests This study reports research findings indicated that there is a significance difference between the mean performances of students in the experimental group than those students in the control group. The students in the experimental group performed better in mechanical technology practice and in retention test than those in the control group. The study recommended that multimedia instructional tool is an effective tool to enhance achievement students on practice skills in mechanical Technology.

  5. Art Appreciation as a Learned Competence: A Museum-based Qualitative Study of Adult Art Specialist and Art Non-Specialist Visitors

    Directory of Open Access Journals (Sweden)

    Rajka Bračun Sova

    2015-12-01

    Full Text Available Since Bourdieu, it has been argued that art appreciation requires “knowledge”. The focus of this qualitative study was to examine art appreciation as a learned competence by exploring two different groups of museum visitors: art specialists and art non-specialists. The research was conducted at Moderna galerija in Ljubljana. Twenty-three adults were recruited and accompanied during their visit to the museum. Participants were requested to “think out loud”, which meant to talk about what they saw, thought, and felt about the artworks. There was a short interview conducted with each participant before entering the museum to gain insight into their art-related and museum-visiting experience. The analysis of the data revealed that some processes of art appreciation were similar within the two groups. Both art specialists and art non-specialists interact with museum objects physically and intellectually; they see contents and formal qualities as a whole; they respond emotionally to artworks; appreciation includes their personal experience; they search museum interpretation/information for their understanding. Some noticeable differences were found. Art specialists respond to artworks with more understanding and are willing to put more effort into art appreciation, whereas art non-specialists respond with less understanding and put less effort into art appreciation. This paper focuses on the differences between the two groups; reflective and spontaneous appreciation of art, objective and subjective appreciation of art and the effort put into art appreciation. The paper ends with a discussion of the implications of the study for the teaching of art and museum education.

  6. Water-mediated interactions between trimethylamine-N-oxide and urea.

    Science.gov (United States)

    Hunger, Johannes; Ottosson, Niklas; Mazur, Kamila; Bonn, Mischa; Bakker, Huib J

    2015-01-07

    The amphiphilic osmolyte trimethylamine-N-oxide (TMAO) is commonly found in natural organisms, where it counteracts biochemical stress associated with urea in aqueous environments. Despite the important role of TMAO as osmoprotectant, the mechanism behind TMAO's action has remained elusive. Here, we study the interaction between urea, TMAO, and water in solution using broadband (100 MHz-1.6 THz) dielectric spectroscopy. We find that the previously reported tight hydrogen bonds between 3 water molecules and the hydrophilic amine oxide group of TMAO, remain intact at all investigated concentrations of urea, showing that no significant hydrogen bonding occurs between the two co-solutes. Despite the absence of direct TMAO-urea interactions, the solute reorientation times of urea and TMAO show an anomalous nonlinear increase with concentration, for ternary mixtures containing equal amounts of TMAO and urea. The nonlinear increase of the reorientation correlates with changes in the viscosity, showing that the combination of TMAO and urea cooperatively enhances the hydrogen-bond structure of the ternary solutions. This nonlinear increase is indicative of water mediated interaction between the two solutes and is not observed if urea is combined with other amphiphilic solutes.

  7. Variation in plant-mediated interactions between rhizobacteria and caterpillars: potential role of soil composition

    NARCIS (Netherlands)

    Pangesti, N.P.D.; Pineda Gomez, A.M.; Dicke, M.; Loon, van J.J.A.

    2015-01-01

    Selected strains of non-pathogenic rhizobacteria can trigger induced systemic resistance (ISR) in plants against aboveground insect herbivores. However, the underlying mechanisms of plant-mediated interactions between rhizobacteria and herbivorous insects are still poorly understood. Using

  8. Facing Sound - Voicing Art

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2013-01-01

    This article is based on examples of contemporary audiovisual art, with a special focus on the Tony Oursler exhibition Face to Face at Aarhus Art Museum ARoS in Denmark in March-July 2012. My investigation involves a combination of qualitative interviews with visitors, observations of the audience´s...... interactions with the exhibition and the artwork in the museum space and short analyses of individual works of art based on reception aesthetics and phenomenology and inspired by newer writings on sound, voice and listening....

  9. Assessment of the State of the Art of Integrated Vehicle Health Management Technologies as Applicable to Damage Conditions

    Science.gov (United States)

    Reveley, Mary S.; Kurtoglu, Tolga; Leone, Karen M.; Briggs, Jeffrey L.; Withrow, Colleen A.

    2010-01-01

    A survey of literature from academia, industry, and other Government agencies assessed the state of the art in current integrated vehicle health management (IVHM) aircraft technologies. These are the technologies that are used for assessing vehicle health at the system and subsystem level. This study reports on how these technologies are employed by major military and commercial platforms for detection, diagnosis, prognosis, and mitigation. Over 200 papers from five conferences from the time period of 2004 to 2009 were reviewed. Over 30 of these IVHM technologies are then mapped into the 17 different adverse event damage conditions identified in a previous study. This study illustrates existing gaps and opportunities for additional research by the NASA IVHM Project.

  10. Remote mixed oxide fabrication facility development. Volume 2. State-of-the-art review of remote maintenance system technology

    International Nuclear Information System (INIS)

    Horgos, R.M.; Masch, M.L.

    1979-06-01

    This report provides a state-of-the-art review of remote systems technology, which includes manipulators, process connectors, vision systems and specialized process systems. A proposed mixed oxide fuel fabrication facility was reviewed and evaluated for identification of major remote maintenance and repair tasks. The technological areas were evaluated on the basis of their suitability or applicability for remote maintenance and repair of a proposed fully remote operating mixed oxide fuel fabrication facility. A technological base exists from which the design criteria for a reliable, remote operating facility can be established. Commercially available systems and components, along with those remote technologies now in development, will require modifications to adapt them to specific plant designs and requirements

  11. How do patients actually experience and use art in hospitals? The significance of interaction: a user-oriented experimental case study.

    Science.gov (United States)

    Nielsen, Stine L; Fich, Lars B; Roessler, Kirsten K; Mullins, Michael F

    2017-12-01

    This article aims to understand patient wellbeing and satisfaction and to qualify the current guidelines for the application of art in hospitals. Employing anthropological methods, we focus on the interactional aspects of art in health interventions. A user-oriented study ranked 20 paintings, followed by an experiment using paintings in the dayroom of five medical wards. Fieldwork was done over a two-week period. During the first week, dayrooms were configured without the presence of art and in the second week were configured with the artworks. Semi-structured interviews, observation, participant observation and informal conversation were carried out and were informed by thermal cameras, which monitored the usage, patient occupation and flow in two of the dayrooms. The study shows that art contributes to creating an environment and atmosphere where patients can feel safe, socialize, maintain a connection to the world outside the hospital and support their identity. We conclude that the presence of visual art in hospitals contributes to health outcomes by improving patient satisfaction as an extended form of health care. The article draws attention to further research perspectives and methods associated with the development of art in hospitals.

  12. Mediation Analysis with Multiple Mediators

    OpenAIRE

    VanderWeele, T.J.; Vansteelandt, S.

    2014-01-01

    Recent advances in the causal inference literature on mediation have extended traditional approaches to direct and indirect effects to settings that allow for interactions and non-linearities. In this paper, these approaches from causal inference are further extended to settings in which multiple mediators may be of interest. Two analytic approaches, one based on regression and one based on weighting are proposed to estimate the effect mediated through multiple mediators and the effects throu...

  13. A chemical arms race at sea mediates algal host-virus interactions.

    Science.gov (United States)

    Bidle, Kay D; Vardi, Assaf

    2011-08-01

    Despite the critical importance of viruses in shaping marine microbial ecosystems and lubricating upper ocean biogeochemical cycles, relatively little is known about the molecular mechanisms mediating phytoplankton host-virus interactions. Recent work in algal host-virus systems has begun to shed novel insight into the elegant strategies of viral infection and subcellular regulation of cell fate, which not only reveal tantalizing aspects of viral replication and host resistance strategies but also provide new diagnostic tools toward elucidating the impact of virus-mediated processes in the ocean. Widespread lateral gene transfer between viruses and their hosts plays a prominent role in host-virus diversification and in the regulation of host-virus infection mechanisms by allowing viruses to manipulate and 'rewire' host metabolic pathways to facilitate infection. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Preschool Interactive Peer Play Mediates Problem Behavior and Learning for Low-Income Children

    Science.gov (United States)

    Bulotsky-Shearer, Rebecca J.; Bell, Elizabeth R.; Romero, Sandy L.; Carter, Tracy M.

    2012-01-01

    The study employed a developmental, ecological, and resiliency framework to examine whether interactive peer play competencies mediated associations between teacher reported problem behavior and learning outcomes for a representative sample of urban low-income children (N = 507 across 46 Head Start classrooms). Structural equation models provided…

  15. Teaching 21st-Century Art Education in a "Virtual" Age: Art Cafe at Second Life

    Science.gov (United States)

    Lu, Lilly

    2010-01-01

    The emerging three-dimensional (3D) virtual world (VW) technology offers great potential for teaching contemporary digital art and growing digital visual culture in 21st-century art education. Such online virtual worlds are built and conceptualized based on information visualization and visual metaphors. Recently, an increasing number of…

  16. Changes in RANKL during the first two years after cART initiation in HIV-infected cART naïve adults

    DEFF Research Database (Denmark)

    Mathiesen, Inger Hee Mabuza; Salem, Mohammad; Gerstoft, Jan

    2017-01-01

    accelerated bone loss could be mediated by increased soluble RANKL (sRANKL) levels associated with CD4+ T cell recovery. METHODS: We used multiplex immunoassays to determine sRANKL and OPG concentrations in plasma from 48 HIV patients at baseline and 12, 24, 48 and 96 weeks after cART initiation. RESULTS......: Soluble RANKL changed significantly over time (overall p = 0.02) with 25% decrease (95% CI: -42 to -5) at week 24 compared to baseline and stabilized at a lower level thereafter. We found no correlation between CD4+ T cell count increment and changes in sRANKL or between percentage change in BMD...... and changes in sRANKL. CONCLUSION: In this study there was no indication that the accelerated bone loss after cART initiation was mediated by early changes in sRANKL due to CD4+ T cell recovery. Future studies should focus on the initial weeks after initiation of cART. TRIAL REGISTRATION: Clinical...

  17. Anisotropic Surface State Mediated RKKY Interaction Between Adatoms on a Hexagonal Lattice

    Science.gov (United States)

    Einstein, Theodore; Patrone, Paul

    2012-02-01

    Motivated by recent numerical studies of Ag on Pt(111), we derive a far-field expression for the RKKY interaction mediated by surface states on a (111) FCC surface, considering the effect of anisotropy in the Fermi edge. The main contribution to the interaction comes from electrons whose Fermi velocity vF is parallel to the vector R connecting the interacting adatoms; we show that in general, the corresponding Fermi wave-vector kF is not parallel to R. The interaction is oscillatory; the amplitude and wavelength of oscillations have angular dependence arising from the anisotropy of the surface state band structure. The wavelength, in particular, is determined by the component of the aforementioned kF that is parallel to R. Our analysis is easily generalized to other systems. For Ag on Pt(111), our results indicate that the RKKY interaction between pairs of adatoms should be nearly isotropic and so cannot account for the anisotropy found in the studies motivating our work.

  18. Health promoting interactive technology: Finnish, Norwegian, Russian and Swedish students' reflections.

    Science.gov (United States)

    Kostenius, Catrine; Hertting, Krister

    2016-09-01

    The aim of this study was to elucidate Finnish, Norwegian, Russian and Swedish students' reflections and ideas on how interactive technology can be used to promote health in school. The data were collected in the northern part of these four countries, and 630 students aged 13-15 filled out the World Health Organization's 'Health Behavior in School-Aged Children' self-completion questionnaire with one additional open question, which is analyzed in this article (n = 419). The phenomenological analysis resulted in four themes: A sense of control, Balancing enjoyable options, Sharing with others and Learning made easier. The students point out that interactive technology promotes empowerment and independence, reduces stress and makes learning easier. They argue for a healthy balance of Internet use for it to be health promoting. According to the students, good relationships increase well-being; and interactive technology can offer a way to socialize, provide a tool for meeting and making new friends, help when not feeling well and give support when encouraging classmates. We argue, based on the findings of the present study and previous research, that students need a combination of freedom and meaningful relationships with adults who have an empowered child perspective, to fully take advantage of the empowering effects of interactive technology. We suggest, as implications for practice, that teachers, school leaders and health care professionals find ways to act as partners using an appreciative process, asking questions on what works well, to make interactive technology an enabling technology to increase health literacy, thus improving health and well-being in students. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Game Mechanics and Bodily Interactions: Designing Interactive Technologies for Sports Training

    DEFF Research Database (Denmark)

    Jensen, Mads Møller

    and enjoyment. Thus, despite being two coexisting research areas, they do not extend or contribute to one another per se. However, bridging this gap by combining skill acquisition knowledge from sports training technologies with motivational game mechanics from bodily games holds great potential for designing...... and developing relevant and engaging training experiences. I term this combination interactive sports training games. This dissertation bridges this gap by exploring how to design and develop bodily interactions that leverage the quality and engagement of sports training by using game mechanics, but also how...... to identify and avoid the pitfalls and challenges that emerge in the process. It further explores how competition can be facilitated in bodily games and how it affects players. These explorations are done by designing, developing and evaluating innovative interactive sports training games. The results...

  20. Interactive lighting art installation in virtual environments as a stimulus for public Ownership in urban development – Brighter Brunnshög

    Directory of Open Access Journals (Sweden)

    Kim Boa

    2018-01-01

    Full Text Available Urban development projects are often 1opposed by residents due to a lack of sense of ownership over the project. This study is a methodological approach in creating interactive lighting art installations in virtual environments to stimulate this sense of ownership. The study is part of the Brighter Brunnshög project, which is the initial stage of the urban development plan for new research centres in Brunnshög, Sweden. The main goal of this research is to explore the impact of virtual lighting art installations on residents´ attitudes toward the urban development of their area. The research is based on qualitative field studies and focus group interviews, and was assessed with questionnaires. The design itself is based on the results of the research data and consists of three criteria; awareness, mutuality, and adaptability. The results of the assessment indicate that interactive lighting art installations in virtual environments have the potential to create awareness of areas under urban development, which is a fundamental condition for creating place attachment, and by extension, a sense of ownership over the project.

  1. Editorial: Special Issue: Art, brain and languages

    DEFF Research Database (Denmark)

    Lewis Brooks, Anthony (aka Tony); Monção, Ana

    2010-01-01

    IJART is a top venue for high quality research and artworks that advance state-of-the-art contributions in the area of the arts and new technologies. The focus is on the multi-disciplinary emerging area of computational art. With the evolution of intelligent devices, sensors and ambient intelligent....../ubiquitous systems, it is not surprising to see many research projects starting to explore the design of intelligent artistic artefacts. This is a new multi-disciplinary area that is still in its infancy. Ambient intelligence(AmI) supports the vision that technology will become invisible, embedded in our natural...

  2. Lectin receptor kinases participate in protein-protein interactions to mediate plasma membrane-cell wall adhesions in Arabidopsis

    NARCIS (Netherlands)

    Gouget, A.; Senchou, V.; Govers, F.; Sanson, A.; Barre, A.; Rougé, P.; Pont-Lezica, R.; Canut, H.

    2006-01-01

    Interactions between plant cell walls and plasma membranes are essential for cells to function properly, but the molecules that mediate the structural continuity between wall and membrane are unknown. Some of these interactions, which are visualized upon tissue plasmolysis in Arabidopsis

  3. Interactive Whiteboards and All That Jazz: Analysing Classroom Activity with Interactive Technologies

    Science.gov (United States)

    Tanner, Howard; Beauchamp, Gary; Jones, Sonia; Kennewell, Steve

    2010-01-01

    The term "orchestration", has been used to describe the teacher's role in activity settings incorporating interactive technologies. This musical analogy suggests pre-planned manipulation of events to generate "performance" leading to learning. However, in two recent projects we have observed how effective teaching and learning…

  4. Development of a security system for assisted reproductive technology (ART).

    Science.gov (United States)

    Hur, Yong Soo; Ryu, Eun Kyung; Park, Sung Jin; Yoon, Jeong; Yoon, San Hyun; Yang, Gi Deok; Hur, Chang Young; Lee, Won Don; Lim, Jin Ho

    2015-01-01

    In the field of assisted reproductive technology (ART), medical accidents can result in serious legal and social consequences. This study was conducted to develop a security system (called IVF-guardian; IG) that could prevent mismatching or mix-ups in ART. A software program was developed in collaboration with outside computer programmers. A quick response (QR) code was used to identify the patients, gametes and embryos in a format that was printed on a label. There was a possibility that embryo development could be affected by volatile organic components (VOC) in the printing material and adhesive material in the label paper. Further, LED light was used as the light source to recognize the QR code. Using mouse embryos, the effects of the label paper and LED light were examined. The stability of IG was assessed when applied in clinical practice after developing the system. A total of 104 cycles formed the study group, and 82 cycles (from patients who did not want to use IG because of safety concerns and lack of confidence in the security system) to which IG was not applied comprised the control group. Many of the label paper samples were toxic to mouse embryo development. We selected a particular label paper (P touch label) that did not affect mouse embryo development. The LED lights were non-toxic to the development of the mouse embryos under any experimental conditions. There were no differences in the clinical pregnancy rates between the IG-applied group and the control group (40/104 = 38.5 % and 30/82 = 36.6 %, respectively). The application of IG in clinical practice did not affect human embryo development or clinical outcomes. The use of IG reduces the misspelling of patient names. Using IG, there was a disadvantage in that each treatment step became more complicated, but the medical staff improved and became sufficiently confident in ART to offset this disadvantage. Patients who received treatment using the IG system also went through a somewhat

  5. The Computer Generated Art/Contemporary Cinematography And The Remainder Of The Art History. A Critical Approach

    Directory of Open Access Journals (Sweden)

    Modesta Lupașcu

    2016-11-01

    Full Text Available The paper analyses the re-conceptualization of the intermedial trope of computer generated images/VFX in recent 3D works/cinema scenes through several examples from art history, which are connected with. The obvious connections between art history and images are not conceived primarily as an embodiment of a painting, the introduction of the real into the image, but prove the reconstructive tendencies of contemporary post-postmodern art. The intellectual, the casual, or the obsessive interaction with art history shown by the new film culture, is already celebrated trough 3D computer generated art, focused to a consistently pictorialist cinematography.

  6. URBAN CHILDHOOD ROUTINES MEDIATED BY TECHNOLOGY: A VISUAL ANALYSIS

    Directory of Open Access Journals (Sweden)

    González-Patiño, Javier

    2011-07-01

    Full Text Available With the goal of documenting routines in which a technological component had some type of impact and observe the influences of immediate environments, exploring meaning and sense, interviews and some observations and, especially, a series of photographs taken by a young girl about her daily life were collected. The purpose of this article is to foster a critical debate about the social and developmental consequences that have been attributed to changes in the living conditions of contemporary Western urban children. For the analytical approach and the analysis of the data, it was especially important to take into consideration the characteristics of the case study participant, a high social class 12 year old pre-adolescent who lives in a home where a large variety of information and communication technology equipment is at her disposal. The conclusions that are presented mainly revolve around two issues. First, related to the emergence of multimodal communication situations, of increasingly semiotic complexity, promoted by digital practices visible in different styles of mediation in the uses of technologies identified as: "convergence", "divergence" and "accessibility". Second, that these technological practices facilitate transformations in space, whether public, private or virtual, altering the importance that traditionally held by other places in the processes of socialization of urban children. This article is published in Spanish.

  7. Techno-economic Performance of State-of-the-Art Oxyfuel Technology for Low-CO2 Coal-fired Electricity Production

    NARCIS (Netherlands)

    Van Der Spek, Mijndert; Eldrup, Nils Henrik; Skagestad, Ragnhild; Ramirez, Andrea

    2017-01-01

    This work presents a techno-economic analysis of a 2015 state-of-the art ASC PC oxyfuel power plant. This work adds to the existing body of techno-economic studies on coal oxycombustion that use less advanced oxyfuel technology and/or steam cycles. The study shows that this oxyfuel configuration has

  8. The impact of ART on union dissolution

    DEFF Research Database (Denmark)

    Martins, Mariana Veloso; Vassard, Ditte; Hougaard, Charlotte Ørsted

    2018-01-01

    .99-1.01). A significant interaction between ART status and common children showed that the risk of break-up was attributed to childlessness regardless of having gone through ART treatment. LIMITATIONS REASON FOR CAUTION: This study did not control for involuntary childlessness, non-ART fertility care (ovulation induction...

  9. Using immersive media and digital technology to communicate Earth Science

    Science.gov (United States)

    Kapur, Ravi

    2016-04-01

    A number of technologies in digital media and interactivity have rapidly advanced and are now converging to enable rich, multi-sensoral experiences which create opportunities for both digital art and science communication. Techniques used in full-dome film-making can now be deployed in virtual reality experiences; gaming technologies can be utilised to explore real data sets; and collaborative interactivity enable new forms of public artwork. This session will explore these converging trends through a number of emerging and forthcoming projects dealing with Earth science, climate change and planetary science.

  10. Implementing Reliability Centered Maintenance (RCM) with State of the Art PT&I Technologies

    Science.gov (United States)

    Hollis, Sean; Sasser, Chase

    2016-01-01

    Building on the work that was started two decades ago, Jacobs Space Operations Group has utilized state of the art PTI technologies to assess the current condition of the assets they manage under the Test and Operations Support Contract (TOSC). Specifically, the Asset Management department leveraged the benefits of ultrasound technology to quantify a motor issue in the Liquid Oxygen Storage Area, and troubleshoot the sources prior to loading the tank to perform Verification and Validation (VV) activities. This technology was efficient, easy to implement, and provided system engineers with data on a possible source of the problem. In situations where legacy motors are exhibiting unexpected noises, it may seem easier to remove and refurbish the motor and replace the bearings because that solution resolves most of the common causes of the noise. However, that solution would have involved additional spending and may not have solved issues stemming from the foundation, if those existed. By utilizing the ultrasound equipment provided by UE Systems, the sound profiles allowed Jacobs TOSC team to determine that the issue resembled a faulty bearing. After replacing the bearing, the unexpected noise ceased.

  11. Write like a visual artist: Tracing the textually mediated art world

    Directory of Open Access Journals (Sweden)

    Janna Klostermann

    2016-12-01

    Full Text Available This study examines the social organisation of Canada’s art world from the standpoint of practising visual artists. Bringing together theories of literacy and institutional ethnography, the article investigates the literacy practices of visual artists, making visible how artists use written texts to participate in public galleries and in the social and institutional relations of the art world. Drawing on extended ethnographic research, including interviews, observational field notes and textual analyses, this study sheds light on the ways visual artists enact particular texts, enact organisational processes, and to enact the social and conceptual worlds they are a part of. Through the lens of visual artists, this study locates two particular texts – the artist statement and the bio statement – in the extended social and institutional relations of the art world.

  12. Let's Draw: Utilizing Interactive White Board to Support Kindergarten Children's Visual Art Learning Practice

    Science.gov (United States)

    Chou, Pao-Nan; Chang, Chi-Cheng; Chen, Mei-Yin

    2017-01-01

    Compared to other academic disciplines, interactive white board (IWB) research in early childhood education is still in its infancy. To add more knowledge base regarding the instructional effectiveness of IWB for young children, this study aimed to investigate educational phenomenon of using an IWB to teach visual art to kindergarten students. The…

  13. Tunable-Range, Photon-Mediated Atomic Interactions in Multimode Cavity QED

    Directory of Open Access Journals (Sweden)

    Varun D. Vaidya

    2018-01-01

    Full Text Available Optical cavity QED provides a platform with which to explore quantum many-body physics in driven-dissipative systems. Single-mode cavities provide strong, infinite-range photon-mediated interactions among intracavity atoms. However, these global all-to-all couplings are limiting from the perspective of exploring quantum many-body physics beyond the mean-field approximation. The present work demonstrates that local couplings can be created using multimode cavity QED. This is established through measurements of the threshold of a superradiant, self-organization phase transition versus atomic position. Specifically, we experimentally show that the interference of near-degenerate cavity modes leads to both a strong and tunable-range interaction between Bose-Einstein condensates (BECs trapped within the cavity. We exploit the symmetry of a confocal cavity to measure the interaction between real BECs and their virtual images without unwanted contributions arising from the merger of real BECs. Atom-atom coupling may be tuned from short range to long range. This capability paves the way toward future explorations of exotic, strongly correlated systems such as quantum liquid crystals and driven-dissipative spin glasses.

  14. Inter-technology knowledge spillovers for energy technologies

    International Nuclear Information System (INIS)

    Nemet, Gregory F.

    2012-01-01

    Both anecdotal evidence and the innovation literature indicate that important advances in energy technology have made use of knowledge originating in other technological areas. This study uses the set of U.S. patents granted from 1976 to 2006 to assess the role of knowledge acquired from outside each energy patent's technological classification. It identifies the effect of external knowledge on the forward citation frequency of energy patents. The results support the claim above. Regression coefficients on citations to external prior art are positive and significant. Further, the effect of external citations is significantly larger than that of other types of citations. Conversely, citations to prior art that is technologically near have a negative effect on forward citation frequency. These results are robust across several alternative specifications and definitions of whether each flow of knowledge is external. Important energy patents have drawn heavily from external prior art categorized as chemical, electronics, and electrical; they cite very little prior art from computers, communications, and medical inventions.

  15. Assessing the relationship between technology readiness and continuance intention in an E-appointment system: relationship quality as a mediator.

    Science.gov (United States)

    Chen, Shih-Chih; Jong, Din; Lai, Min-Tsai

    2014-09-01

    Numerous types of self-service technologies have prevailed due to innovations in network and information technology. To hospitals, patient intentions to continue to use the e-appointment system are crucial. Previous investigations discussed only the relationships between the technology readiness of users and their continuance intentions, and ignored the most important mediator, relationship quality. This study explored the relationships among technology readiness, relationship quality, and continuance intention. The research results demonstrated that both optimism and innovativeness significantly and positively influenced continuance intention through the mediating effect of relationship quality. However, discomfort and insecurity hid not significantly influence relationship quality or continuance intention. Finally, theoretical contributions, managerial implications and future research directions were discussed.

  16. NASA Science Engagement Through "Sky Art"

    Science.gov (United States)

    Bethea, K. L.; Damadeo, K.

    2013-12-01

    Sky Art is a NASA-funded online community where the public can share in the beauty of nature and the science behind it. At the center of Sky Art is a gallery of amateur sky photos submitted by users that are related to NASA Earth science mission research areas. Through their submissions, amateur photographers from around the world are engaged in the process of making observations, or taking pictures, of the sky just like many NASA science instruments. By submitting their pictures and engaging in the online community discussions and interactions with NASA scientists, users make the connection between the beauty of nature and atmospheric science. Sky Art is a gateway for interaction and information aimed at drawing excitement and interest in atmospheric phenomena including sunrises, sunsets, moonrises, moonsets, and aerosols, each of which correlates to a NASA science mission. Educating the public on atmospheric science topics in an informal way is a central goal of Sky Art. NASA science is included in the community through interaction from scientists, NASA images, and blog posts on science concepts derived from the images. Additionally, the website connects educators through the formal education pathway where science concepts are taught through activities and lessons that align with national learning standards. Sky Art was conceived as part of the Education and Public Outreach program of the SAGE III on ISS mission. There are currently three other NASA mission involved with Sky Art: CALIPSO, GPM, and CLARREO. This paper will discuss the process of developing the Sky Art online website, the challenges of growing a community of users, as well as the use of social media and mobile applications in science outreach and education.

  17. Outcome of assisted reproductive technology (ART) and subsequent self-reported life satisfaction.

    Science.gov (United States)

    Kuivasaari-Pirinen, Paula; Koivumaa-Honkanen, Heli; Hippeläinen, Maritta; Raatikainen, Kaisa; Heinonen, Seppo

    2014-01-01

    To compare life satisfaction between women with successful or unsuccessful outcome after assisted reproductive treatment (ART) by taking into account the time since the last ART. Cohort study. Tertiary hospital. A total of 987 consecutive women who had undergone ART during 1996-2007 were invited and altogether 505 women participated in the study. A postal enquiry with a life satisfaction scale. Self-reported life satisfaction in respect to the time since the last ART. In general, women who achieved a live birth after ART had a significantly higher life satisfaction than those who had unsuccessful ART, especially when compared in the first three years. The difference disappeared in the time period of 6-9 years after ART. The unsuccessfully treated women who had a child by some other means before or after the unsuccessful ART had comparable life satisfaction with successfully treated women even earlier. Even if unsuccessful ART outcome is associated with subsequent lower level of life satisfaction, it does not seem to threaten the long-term wellbeing.

  18. Plant-plant interactions mediate the plastic and genotypic response of Plantago asiatica to CO

    NARCIS (Netherlands)

    Loon, Van Marloes P.; Rietkerk, Max; Dekker, Stefan C.; Hikosaka, Kouki; Ueda, Miki U.; Anten, Niels P.R.

    2016-01-01

    Background and Aims The rising atmospheric CO2 concentration ([CO2]) is a ubiquitous selective force that may strongly impact species distribution and vegetation functioning. Plant-plant interactions could mediate the trajectory of vegetation responses to elevated

  19. A Review of Wireless Sensor Technologies and Applications in Agriculture and Food Industry: State of the Art and Current Trends

    OpenAIRE

    Ruiz-Garcia, Luis; Lunadei, Loredana; Barreiro, Pilar; Robla, Jose Ignacio

    2009-01-01

    The aim of the present paper is to review the technical and scientific state of the art of wireless sensor technologies and standards for wireless communications in the Agri- Food sector. These technologies are very promising in several fields such as environmental monitoring, precision agriculture, cold chain control or traceability. The paper focuses on WSN (Wireless Sensor Networks) and RFID (Radio Frequency Identification), presenting the different systems available, recent developments a...

  20. Art Therapy

    DEFF Research Database (Denmark)

    Skov, Vibeke; Pedersen, Inge Nygaard

    2014-01-01

    Abstract Based on a Jungian approach, this article will introduce an integrative model to therapeutic change using art therapy methods as practical tools, with the aim of improving quality of life and in the prevention of depression. In a research study involving six participants, painting, clay...... work and drumming were used together with imagination and personal dialogues linked to the artwork. These art therapy processes attempted to combine the participant’s experience of inner and outer reality. The effect of gaining more knowledge about their inner reality using dreams and symbols......, was that participants gained a new understanding about their personal life. In addition, some participants were able to continue to use art therapy experiences as selfdevelopmental tools after the research study terminated. Jung’s description of the interactive relationship between the two living parts of the psyche...

  1. Writing on Pigments in Natural History and Art Technology in Sixteenth-Century Germany and Switzerland.

    Science.gov (United States)

    Oltrogge, Doris

    2015-01-01

    Renaissance painters used a number of inorganic color materials. The development of mineralogy as a discipline opened a new discourse on mineral pigments. Agricola and other naturalists were familiar with the contemporary writings on art technology, but their focus was different. Therefore, the exchange of knowledge between these two color worlds remained selective. One possible meeting point was the Kunstkammer where the study of natural objects and materials was combined with an interest in the manual execution of a painting.

  2. Analysis of the Varicella-Zoster Virus IE62 N-Terminal Acidic Transactivating Domain and Its Interaction with the Human Mediator Complex▿

    OpenAIRE

    Yamamoto, Shinobu; Eletsky, Alexander; Szyperski, Thomas; Hay, John; Ruyechan, William T.

    2009-01-01

    The varicella-zoster virus major transactivator, IE62, contains a potent N-terminal acidic transcriptional activation domain (TAD). Our experiments revealed that the minimal IE62 TAD encompasses amino acids (aa) 19 to 67. We showed that the minimal TAD interacts with the human Mediator complex. Site-specific mutations revealed residues throughout the minimal TAD that are important for both activation and Mediator interaction. The TAD interacts directly with aa 402 to 590 of the MED25 subunit,...

  3. Metal-metal interaction mediates the iron induction of Drosophila MtnB

    International Nuclear Information System (INIS)

    Qiang, Wenjia; Huang, Yunpeng; Wan, Zhihui; Zhou, Bing

    2017-01-01

    Metallothionein (MT) protein families are a class of small and universal proteins rich in cysteine residues. They are synthesized in response to heavy metal stresses to sequester the toxic ions by metal-thiolate bridges. Five MT family members, namely MtnA, MtnB, MtnC, MtnD and MtnE, have been discovered and identified in Drosophila. These five isoforms of MTs are regulated by metal responsive transcription factor dMTF-1 and play differentiated but overlapping roles in detoxification of metal ions. Previous researches have shown that Drosophila MtnB responds to copper (Cu), cadmium (Cd) and zinc (Zn). Interestingly in this study we found that Drosophila MtnB expression also responds to elevated iron levels in the diet. Further investigations revealed that MtnB plays limited roles in iron detoxification, and the direct binding of MtnB to ferrous iron in vitro is also weak. The induction of MtnB by iron turns out to be mediated by iron interference of other metals, because EDTA at even a partial concentration of that of iron can suppress this induction. Indeed, in the presence of iron, zinc homeostasis is altered, as reflected by expression changes of zinc transporters dZIP1 and dZnT1. Thus, iron-mediated MtnB induction appears resulting from interrupted homeostasis of other metals such as zinc, which in turns induced MtnB expression. Metal-metal interaction may more widely exist than we expected. - Highlights: • Metallothionein B expression is regulated by iron in Drosophila melanogaster. • MtnB has limited physiological roles in iron detoxification. • Binding affinity of MtnB to iron is weak in vitro. • Induction of Drosophila MtnB by iron is mediated indirectly through metal-metal interaction.

  4. Global Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions

    Science.gov (United States)

    2016-12-01

    Award Number: W81XWH-11-2-0175 TITLE: Global Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions PRINCIPAL...Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions 5b. GRANT NUMBER W81XWH-11-2-0175 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...genetic diversity in the population, in hospitalized children with severe dengue illness and cluster investigation of their neighborhoods, and by using

  5. Instrumental Genesis in Technology-Mediated Learning: From Double Stimulation to Expansive Knowledge Practices

    Science.gov (United States)

    Ritella, Giuseppe; Hakkarainen, Kai

    2012-01-01

    The purpose of the present paper is to examine the socio-cultural foundations of technology-mediated collaborative learning. Toward that end, we discuss the role of artifacts in knowledge-creating inquiry, relying on the theoretical ideas of Carl Bereiter, Merlin Donald, Pierre Rabardel, Keith Sawyer and L. S. Vygotsky. We argue that epistemic…

  6. DMPD: Signal transduction pathways mediated by the interaction of CpG DNA withToll-like receptor 9. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 14751759 Signal transduction pathways mediated by the interaction of CpG DNA withTo...;16(1):17-22. (.png) (.svg) (.html) (.csml) Show Signal transduction pathways mediated by the interaction of... CpG DNA withToll-like receptor 9. PubmedID 14751759 Title Signal transduction pathways media

  7. Modern analytic methods applied to the art and archaeology

    International Nuclear Information System (INIS)

    Tenorio C, M. D.; Longoria G, L. C.

    2010-01-01

    The interaction of diverse areas as the analytic chemistry, the history of the art and the archaeology has allowed the development of a variety of techniques used in archaeology, in conservation and restoration. These methods have been used to date objects, to determine the origin of the old materials and to reconstruct their use and to identify the degradation processes that affect the integrity of the art works. The objective of this chapter is to offer a general vision on the researches that have been realized in the Instituto Nacional de Investigaciones Nucleares (ININ) in the field of cultural goods. A series of researches carried out in collaboration with national investigators and of the foreigner is described shortly, as well as with the great support of degree students and master in archaeology of the National School of Anthropology and History, since one of the goals that have is to diffuse the knowledge of the existence of these techniques among the young archaeologists, so that they have a wider vision of what they could use in an in mediate future and they can check hypothesis with scientific methods. (Author)

  8. Values-led Participatory Design - Mediating the Emergence of Values

    DEFF Research Database (Denmark)

    Iversen, Ole Sejer; Leong, Tuck Wah

    2012-01-01

    There is a growing interest in values-led inquiries within participatory design. One approach argues that working with values is a recursive 3-phase process that supports the emergence, development and grounding of values. In this paper we focus solely upon the emergence phase, proposing...... an approach that can support the emergence of values during the initial phase of a values-led inquiry. To illustrate this approach and to ground our discussion, we draw from a recent participatory design case where we were engaged in the design of digital technology to support the experiences of young adults...... with severe intellectual disabilities, in an art museum. By describing how we establish, negotiate and the debrief values during this initial phase of a values-led inquiry. By foregrounding both explicit and implicit mediation in the PD process we show how a theoretical understanding of mediation can...

  9. Non-Identity-Mediated CRISPR-Bacteriophage Interaction Mediated via the Csy and Cas3 Proteins ▿#

    Science.gov (United States)

    Cady, Kyle C.; O'Toole, George A.

    2011-01-01

    Studies of the Escherichia, Neisseria, Thermotoga, and Mycobacteria clustered regularly interspaced short palindromic repeat (CRISPR) subtypes have resulted in a model whereby CRISPRs function as a defense system against bacteriophage infection and conjugative plasmid transfer. In contrast, we previously showed that the Yersinia-subtype CRISPR region of Pseudomonas aeruginosa strain UCBPP-PA14 plays no detectable role in viral immunity but instead is required for bacteriophage DMS3-dependent inhibition of biofilm formation by P. aeruginosa. The goal of this study is to define the components of the Yersinia-subtype CRISPR region required to mediate this bacteriophage-host interaction. We show that the Yersinia-subtype-specific CRISPR-associated (Cas) proteins Csy4 and Csy2 are essential for small CRISPR RNA (crRNA) production in vivo, while the Csy1 and Csy3 proteins are not absolutely required for production of these small RNAs. Further, we present evidence that the core Cas protein Cas3 functions downstream of small crRNA production and that this protein requires functional HD (predicted phosphohydrolase) and DEXD/H (predicted helicase) domains to suppress biofilm formation in DMS3 lysogens. We also determined that only spacer 1, which is not identical to any region of the DMS3 genome, mediates the CRISPR-dependent loss of biofilm formation. Our evidence suggests that gene 42 of phage DMS3 (DMS3-42) is targeted by CRISPR2 spacer 1 and that this targeting tolerates multiple point mutations between the spacer and DMS3-42 target sequence. This work demonstrates how the interaction between P. aeruginosa strain UCBPP-PA14 and bacteriophage DMS3 can be used to further our understanding of the diverse roles of CRISPR system function in bacteria. PMID:21398535

  10. Increasing Responsive Parent–Child Interactions and Joint Engagement: Comparing the Influence of Parent-Mediated Intervention and Parent Psychoeducation

    Science.gov (United States)

    Gulsrud, Amanda; Kasari, Connie

    2016-01-01

    Enhancing immediate and contingent responding by caregivers to children’s signals is an important strategy to support social interactions between caregivers and their children with autism. Yet, there has been limited examination of parents’ responsive behaviour in association with children’s social behaviour post caregiver-mediated intervention. Eighty-five dyads were randomized to one of two 10-week caregiver-training interventions. Parent–child play interactions were coded for parental responsivity and children’s joint engagement. Significant gains in responsivity and time jointly engaged were found post JASPER parent-mediated intervention over a psychoeducation intervention. Further, combining higher levels of responsive behaviour with greater adoption of intervention strategies was associated with greater time jointly engaged. Findings encourage a focus on enhancing responsive behaviour in parent-mediated intervention models. PMID:26797940

  11. Cell-cell interactions mediate cytoskeleton organization and collective endothelial cell chemotaxis.

    Science.gov (United States)

    Shamloo, Amir

    2014-09-01

    This study investigates the role of cell-cell and cell-ligand interactions in cytoskeleton organization of endothelial cells (ECs) and their directional migration within a microfluidic device. The migration of ECs in response to a biochemical factor was studied. Mathematical analysis of the cell migration pathways and cellular cytoskeleton revealed that directional migration, migration persistence length, migration speed, and cytoskeletal stress fiber alignment can be mediated by the level of cell contacts as well as the presence or absence of a biochemical polarizing factor. It was shown that in the presence of a biochemical polarizing factor, higher cell density and more frequent cell contacts has a reinforcing effect on collective cell chemotaxis. In contrast, in the absence of a polarizing factor, high cell density can decrease or suppress the ability of the cells to migrate. Also, the correlation of actin stress fiber organization and alignment with directional migration of ECs was investigated. It was shown that in the presence of a biochemical polarizing factor, stress fibers within the cytoskeleton of ECs can be significantly aligned parallel to the gradient direction when the cells have higher level of contacts. The results also show that the organization and alignment of actin stress fibers is mediated by cell adhesion junctions during collective cell migration and introduce cell-cell interactions as a key factor during collective cell chemotaxis. © 2014 Wiley Periodicals, Inc.

  12. Environmental impacts and benefits of state-of-the-art technologies for E-waste management.

    Science.gov (United States)

    Ikhlayel, Mahdi

    2017-10-01

    This study aims to evaluate the environmental impacts and benefits of state-of-the-art technologies for proper e-waste handling using Jordan as a case study. Life Cycle Assessment (LCA) was employed to evaluate five advanced management systems represent state-of-the-art treatment technologies, including sanitary landfilling; proper recycling of metals, materials, and precious metals (PMs); and incineration of plastic and the hazardous portion of printed circuit boards (PCBs). Six e-waste products that contribute the most to the e-waste in Jordan were included in the assessment of each scenario, which resulted in 30 total cases of e-waste management. The findings indicated that landfills for the entire components of the e-waste stream are the worst option and should be avoided. The most promising e-waste management scenario features integrated e-waste processes based on the concept of Integrated Waste Management (IWM), including recycling materials such as non-PMs and PMs, incinerating plastic and the hazardous content of PCBs using the energy recovered from incineration, and using sanitary landfills of residues. For this scenario, the best environmental performance was obtained for the treatment of mobile phones. Incineration of the portion of hazardous waste using energy recovery is an option that deserves attention. Because scenario implementation depends on more than just the environmental benefits (e.g., economic cost and technical aspects), the study proposes a systematic approach founded on the IWM concept for e-waste management scenario selection. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. ICT in the Arts

    DEFF Research Database (Denmark)

    Brooks, Anthony Lewis

    2014-01-01

    Increased use of ICT in art projects opens novel opportunities for contemporary artists seeking innovative means to create and express beyond the traditional in new ways and places. This can also be beyond what is conventionally considered art. Thus, wider and transdisciplinary philosophical...... perspectives become apparent. Specific examples are presented from the author’s portfolio with a focus on biofeedback and unencumbered gesture control of digital media. Parallel is increased attention to creativity seen from within academia and industry with specific education programmes reflecting how...... creative industries are important to economic well being in society. This contribution1 presents across these borders through introducing an international conference series titled ArtsIT within a special issue of the International Journal on Arts and Technology, which are vehicles for contemporary artists...

  14. Collaborative virtual environments art exhibition

    Science.gov (United States)

    Dolinsky, Margaret; Anstey, Josephine; Pape, Dave E.; Aguilera, Julieta C.; Kostis, Helen-Nicole; Tsoupikova, Daria

    2005-03-01

    This panel presentation will exhibit artwork developed in CAVEs and discuss how art methodologies enhance the science of VR through collaboration, interaction and aesthetics. Artists and scientists work alongside one another to expand scientific research and artistic expression and are motivated by exhibiting collaborative virtual environments. Looking towards the arts, such as painting and sculpture, computer graphics captures a visual tradition. Virtual reality expands this tradition to not only what we face, but to what surrounds us and even what responds to our body and its gestures. Art making that once was isolated to the static frame and an optimal point of view is now out and about, in fully immersive mode within CAVEs. Art knowledge is a guide to how the aesthetics of 2D and 3D worlds affect, transform, and influence the social, intellectual and physical condition of the human body through attention to psychology, spiritual thinking, education, and cognition. The psychological interacts with the physical in the virtual in such a way that each facilitates, enhances and extends the other, culminating in a "go together" world. Attention to sharing art experience across high-speed networks introduces a dimension of liveliness and aliveness when we "become virtual" in real time with others.

  15. Anisotropic surface-state-mediated RKKY interaction between adatoms on a hexagonal lattice

    Science.gov (United States)

    Patrone, Paul N.; Einstein, T. L.

    2012-01-01

    Motivated by recent numerical studies of Ag on Pt(111), we derive an expression for the RKKY interaction mediated by surface states, considering the effect of anisotropy in the Fermi edge. Our analysis is based on a stationary phase approximation. The main contribution to the interaction comes from electrons whose Fermi velocity vF is parallel to the vector R connecting the interacting adatoms; we show that, in general, the corresponding Fermi wave vector kF is not parallel to R. The interaction is oscillatory; the amplitude and wavelength of oscillations have angular dependence arising from the anisotropy of the surface-state band structure. The wavelength, in particular, is determined by the projection of this kF (corresponding to vF) onto the direction of R. Our analysis is easily generalized to other systems. For Ag on Pt(111), our results indicate that the RKKY interaction between pairs of adatoms should be nearly isotropic and so cannot account for the anisotropy found in the studies motivating our work. However, for metals with surface-state dispersions similar to Be(101¯0), we show that the RKKY interaction should have considerable anisotropy.

  16. A Critical Review of the State-of-the-Art in Autonomous Land Vehicle Systems and Technology; TOPICAL

    International Nuclear Information System (INIS)

    DURRNAT-WHYTE, HUGH

    2001-01-01

    This report describes the current state-of-the-art in Autonomous Land Vehicle (ALV) systems and technology. Five functional technology areas are identified and addressed. For each a brief, subjective, preface is first provided which envisions the necessary technology for the deployment of an operational ALV system. Subsequently, a detailed literature review is provided to support and elaborate these views. It is further established how these five technology areas fit together as a functioning whole. The essential conclusion of this report is that the necessary sensors, algorithms and methods to develop and demonstrate an operationally viable all-terrain ALV already exist and could be readily deployed. A second conclusion is that the successful development of an operational ALV system will rely on an effective approach to systems engineering. In particular, a precise description of mission requirements and a clear definition of component functionality is essential

  17. Mutually Beneficial Foreign Language Learning: Creating Meaningful Interactions through Video-Synchronous Computer-Mediated Communication

    Science.gov (United States)

    Kato, Fumie; Spring, Ryan; Mori, Chikako

    2016-01-01

    Providing learners of a foreign language with meaningful opportunities for interactions, specifically with native speakers, is especially challenging for instructors. One way to overcome this obstacle is through video-synchronous computer-mediated communication tools such as Skype software. This study reports quantitative and qualitative data from…

  18. Small Wind Turbine Technology Assessment; Estado del Arte de la Tecnologia de Pequeos Aerogeneradores

    Energy Technology Data Exchange (ETDEWEB)

    Avia Aranda, F; Cruz Cruz, I [CIEMAT. Madrid (Spain)

    1999-03-01

    The result of the study carried out under the scope of the ATYCA project Test Plant of Wind Systems for Isolated Applications, about the state of art of the small wind turbine technology (wind turbines with swept area smaller than 40 m``2) is presented. The study analyzes the collected information on 60 models of wind turbines from 23 manufactures in the worldwide market. Data from Chinese manufacturers, that have a large participation in the total number of small turbines in operation, are not included, due to the unavailability of the technical information. (Author) 15 refs.

  19. Prosthetic Smart Socket Technology to Improve Patient Interaction, Usability, Comfort, Fit and Function

    Science.gov (United States)

    2017-10-01

    impact on society beyond science and technology ? Nothing to report at this time. 5. CHANGES/PROBLEMS: Changes in approach and reasons for...AWARD NUMBER: W81XWH-16-1-0785 TITLE: Prosthetic Smart Socket Technology to Improve Patient Interaction, Usability, Comfort, Fit and Function...2016 - 29 Sep 2017 4. TITLE AND SUBTITLE Prosthetic Smart Socket Technology to Improve Patient Interaction, Usability, Comfort, Fit and Function 5a

  20. ART-SCIENCE OF THE SPACE AGE: towards a platform for art-science collaborations at ESTEC

    Science.gov (United States)

    Domnitch, E.; Gelfand, D.

    2015-10-01

    In 2013, in collaboration with ESTEC scientist Bernard Foing and the ArtScience Interfaculty (Royal Academy of the Arts, The Hague), Synergetica Lab (Amsterdam) developed a course, which was repeated in 2015, for bachelor's and master's students aimed at seeding interactions with ESA researchers. The participants created artworks investigating space travel, radio astronomy, microgravity, ecosynthesis as well as extraterrestrial physics and architecture [1] [2]. After their initial presentation at the Royal Academy, these artworks were shown at ESTEC, TodaysArt Festival (The Hague), and TEC ART (Rotterdam). These presentations prompted diverse future collaborations and outreach opportunities, including the European Planetary Science Congress 2014 (Cascais) and the AxS Festival (Los Angeles).

  1. Media Art

    DEFF Research Database (Denmark)

    Ekman, Ulrik

    2015-01-01

    environments, experience time, and develop identities individually and socially. Interviews with working media artists lend further perspectives on these cultural transformations. Drawing on cultural theory, new media art studies, human-computer interaction theory, and software studies, this cutting-edge book...... critically unpacks the complex ubiquity-effects confronting us every day....

  2. O-Tu-Kapua ('What Clouds See'): A Mixed Reality Experience Bridging Art, Science and Technology in Meaningful Ways

    Science.gov (United States)

    Jowsey, Susan; Aguayo, Claudio

    2017-01-01

    Mixed Reality learning environments can provide opportunities to educationally enhance previously isolated scientific concepts by using art and technology as mediums for understanding the world. Participatory experiences provide a kinetic means of comprehending often-abstract knowledge, creating the conditions for sensory learning that is…

  3. Art/Net/Work

    DEFF Research Database (Denmark)

    Andersen, Christian Ulrik; Lindstrøm, Hanne

    2006-01-01

    The seminar Art|Net|Work deals with two important changes in our culture. On one side, the network has become essential in the latest technological development. The Internet has entered a new phase, Web 2.0, including the occurrence of as ‘Wiki’s’, ‘Peer-2-Peer’ distribution, user controlled...... on the ‘network’ itself as a phenomenon and are often using technological networks as a mean of production and distribution. This changes the artistic practice and the distribution channels of art works – and the traditional notions of ‘work’, ‘origin’ and ‘rights’ are increasingly perceived as limiting...... the praxis of the artist. We see different kinds of interventions and activism (including ‘hacktivism’) using the network as a way of questioning the invisible rules that govern public and semi-public spaces. Who ‘owns’ them? What kind of social relationships do they generate? On what principle...

  4. Between cinema and contemporary art Entre cinema e arte contemporânea

    OpenAIRE

    André Parente; Victa Carvalho

    2009-01-01

    Between cinema and contemporary art — How is the new media changing the original architectural, technological, and discursive dimensions of the "device" cinema? How do these experiments create new displacements or points of departure from the instituted representation model? The notion of "device" allows us to rethink cinema, avoiding cleavages and technological, historical and aesthetic determinisms. Unlike the dominant cinema, several cinematographic works reinvent ...

  5. Future Computing Technology (3/3)

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Computing of the future will be affected by a number of fundamental technologies in development today, many of which are already on the way to becoming commercialized. In this series of lectures, we will discuss hardware and software development that will become mainstream in the timeframe of a few years and how they will shape or change the computing landscape - commercial and personal alike. Topics range from processor and memory aspects, programming models and the limits of artificial intelligence, up to end-user interaction with wearables or e-textiles. We discuss the impact of these technologies on the art of programming, the data centres of the future and daily life. On the third day of the Future Computing Technology series, we will touch on societal aspects of the future of computing. Our perception of computers may at time seem passive, but in reality we are a vital chain of the feedback loop. Human-computer interaction, innovative forms of computers, privacy, process automation, threats and medica...

  6. Performing arts as a social technology for community health promotion in northern Ghana

    Directory of Open Access Journals (Sweden)

    Michael Frishkopf

    2016-02-01

    Full Text Available Objective: We present first-phase results of a performing arts public health intervention, ‘Singing and Dancing for Health,’ aiming to promote healthier behaviors in Ghana’s impoverished Northern Region. We hypothesize that live music and dance drama provide a powerful technology to overcome barriers such as illiteracy, lack of adequate media access, inadequate health resources, and entrenched sociocultural attitudes. Our research objective is to evaluate this claim. Methods: In this first phase, we evaluated the effectiveness of arts interventions in improving knowledge and behaviors associated with reduced incidence of malaria and cholera, focusing on basic information and simple practices, such as proper hand washing. Working with the Youth Home Cultural Group, we codeveloped two ‘dance dramas’ delivering health messages through dialog, lyrics, and drama, using music and dance to attract spectators, focus attention, infuse emotion, and socialize impact. We also designed knowledge, attitude, and behavior surveys as measurement instruments. Using purposive sampling, we selected three contrasting test villages in the vicinity, contrasting in size and demographics. With cooperation of chiefs, elders, elected officials, and Ghana Health Service officers, we conducted a baseline survey in each village. Next, we performed the interventions, and subsequently conducted follow-up surveys. Using a more qualitative approach, we also tracked a select subgroup, conducted focus group studies, and collected testimonials. Surveys were coded and data were analyzed by Epi Info. Results: Both quantitative and qualitative methods indicated that those who attended the dance drama performances were likelier than those who did not attend to list the causal, preventive, and transmission factors of malaria and cholera. Also, the same attendees were likelier than nonattendees to list some activities they do to prevent malaria, cholera, and other sanitation

  7. Preparing for Assisted Reproductive Technology

    Science.gov (United States)

    ... CDC Cancel Submit Search The CDC Assisted Reproductive Technology (ART) Note: Javascript is disabled or is not ... visit this page: About CDC.gov . Assisted Reproductive Technology (ART) What Is ART Patient Resources Preparing for ...

  8. Interactive Teaching Across Culture and Technology

    OpenAIRE

    Chumbo, Isabel (Ed.); Silva, Elisabete Mendes (Ed.)

    2015-01-01

    Remember the time when you had a teacher in front of a blackboard endlessly talking, sometimes in a rambling way to students? Those days are gone. This project is a proof of that and aims at palliating students’ boredom. Interactive Teaching Materials across Culture and Technology (INTACT) intends to present an alternative way in the teaching paradigm as it intends to be a resourceful tool in the teaching/learning process. Both teachers and students can work together coopera...

  9. The Factors Influencing Young Children's Social Interaction in Technology Integration

    Science.gov (United States)

    Lim, Eun Mee

    2015-01-01

    When technology integration is accomplished successfully in early childhood education settings, children tend to interact more with one another and exchange information related to computer tasks as well as the overall classroom on-going curriculum themes. Therefore, to explore how young children are interacting in computer areas when using…

  10. Proyectando siluetas: mediación artística

    OpenAIRE

    MELERO GONZÁLEZ, ESTHER

    2016-01-01

    [EN] This final degree Project aims to be an experiential introduction to the field of A rtistic Mediation and the Art Therapy through a basic study about the fundamental concepts of both in order to apply them in the way that our degree trains us and adding the support and monitoring of professionals from this field of knowledge along with my tutor and director of the Master in Art Therapy at our university. We worked in a...

  11. Development of soil-structure interaction analysis method (II) - Volume 1

    International Nuclear Information System (INIS)

    Chang, S. P.; Ko, H. M.; Park, H. K. and others

    1994-02-01

    This project includes following six items : free field analysis for the determination of site input motions, impedance analysis which simplifies the effects of soil-structure interaction by using lumped parameters, soil-structure interaction analysis including the material nonlinearity of soil depending on the level of strains, strong geometric nonlinearity due to the uplifting of the base, seismic analysis of underground structure such as varied pipes, seismic analysis of liquid storage tanks. Each item contains following contents respectively : state-of-the-art review on each item and data base construction on the past researches, theoretical review on the technology of soil-structure interaction analysis, proposing preferable technology and estimating the domestic applicability, proposing guidelines for evaluation of safety and analysis scheme

  12. Young children accessing the learning of others: mediation through the ‘witnessing’ of others’ gestural interactions

    Directory of Open Access Journals (Sweden)

    Karl Wall

    2006-05-01

    Full Text Available Contextualisation Children’s interactions in the classroom arguably underpin many of the learning events and activities they experience. These may involve their classroom teacher, teaching assistants, other adults (including, in the primary school, context, parents / carers, their peers or other children entering the room where they are working. The paper that follows, reflects on the nature of such interactions, focusing on gestural behaviours, observed as part of a programme of doctoral study. It explores the notion of how the ‘witnessing’ of others’ interactions may contribute to and inform the behaviour, understanding and learning of a child, as they work with their peers and a teacher on a grouped task. In so doing, it re-examines the notion of the more experienced other, associated with Vygotsky’s ideas on social interaction in a pedagogic context and draws on a range of disciplines for both practical and theoretical inspiration. Abstract: Arising from a study of grouped 5-6 year olds’ gestural interactions, an extension to Vygotskian notions of mediation is proposed. This is developed through a consideration of ideas grounded in: cultural psychology, situated learning, distributed cognition , the analysis of ‘task affordances’. The potential significance and role of a child’s ‘witnessing’ of the mediational interactions of others is discussed informed by data drawn from the author’s current research. The implications for teachers’ practice as a more ‘experienced other’, in such interactions, are briefly discussed.

  13. Self-Care Technologies in HCI

    DEFF Research Database (Denmark)

    Nunes, Francisco; Verdezoto, Nervo; Fitzpatrick, Geraldine

    2015-01-01

    Many studies show that self-care technologies can support patients with chronic conditions and their carers in understanding the ill body and increasing control of their condition. However, many of these studies have largely privileged a medical perspective and thus overlooked how patients......-care, and increasing the influence on medical research and practice around self-care technology....... and carers integrate self-care into their daily lives and mediate their conditions through technology. In this review, we focus on how patients and carers use and experience self-care technology through a Human-Computer Interaction (HCI) lens. We analyse studies of self-care published in key HCI journals...

  14. New interactions in the dark sector mediated by dark energy

    International Nuclear Information System (INIS)

    Brookfield, Anthony W.; Bruck, Carsten van de; Hall, Lisa M. H.

    2008-01-01

    Cosmological observations have revealed the existence of a dark matter sector, which is commonly assumed to be made up of one particle species only. However, this sector might be more complicated than we currently believe: there might be more than one dark matter species (for example, two components of cold dark matter or a mixture of hot and cold dark matter) and there may be new interactions between these particles. In this paper we study the possibility of multiple dark matter species and interactions mediated by a dark energy field. We study both the background and the perturbation evolution in these scenarios. We find that the background evolution of a system of multiple dark matter particles (with constant couplings) mimics a single fluid with a time-varying coupling parameter. However, this is no longer true on the perturbative level. We study the case of attractive and repulsive forces as well as a mixture of cold and hot dark matter particles

  15. Colloquium: Digital Technologies--Help or Hindrance for the Humanities?

    Science.gov (United States)

    Barker, Elton; Bissell, Chris; Hardwick, Lorna; Jones, Allan; Ridge, Mia; Wolffe, John

    2012-01-01

    This article offers reflections arising from a recent colloquium at the Open University on the implications of the development of digital humanities for research in arts disciplines, and also for their interactions with computing and technology. Particular issues explored include the ways in which the digital turn in humanities research is also a…

  16. Graphics Tablet Technology in Second Year Thermal Engineering Teaching

    Science.gov (United States)

    Carrillo, Antonio; Cejudo, José Manuel; Domínguez, Fernando; Rodríguez, Eduardo

    2013-01-01

    Graphics tablet technology is well known in markets such as manufacturing, graphics arts and design but it has not yet found widespread acceptance for university teaching. A graphics tablet is an affordable teaching tool that combines the best features from traditional and new media. It allows developing a progressive, interactive lecture (as a…

  17. Technology and plasma-materials interaction processes of tokamak disruptions

    International Nuclear Information System (INIS)

    McGrath, R.T.; Kellman, A.G.

    1992-01-01

    A workshop on the technology and plasma-materials interaction processes of tokamak disruptions was held April 3, 1992 in Monterey, California, as a satellite meeting of the 10th International Conference on Plasma-Surface Interactions. The objective was to bring together researchers working on disruption measurements in operating tokamaks, those performing disruption simulation experiments using pulsed plasma gun, electron beam and laser systems, and computational physicists attempting to model the evolution and plasma-materials interaction processes of tokamak disruptions. This is a brief report on the workshop. 4 refs

  18. Consideration on the interaction between society and nuclear technology

    International Nuclear Information System (INIS)

    Shinoda, Yoshihiko

    2007-01-01

    A social conflict over nuclear technology arises from the different interactions between society and nuclear technology. The purpose of this review is to grasp the essential points of this social conflict from a social viewpoint. These essential points can be discerned by interpreting results of polls about nuclear technology and the future of society in general. As a result, attitudes towards nuclear technology can be explained in terms of differences of general views on society such as social order or social progress. The attitudes of people toward nuclear technology were divided into strong agreement, weak agreement, weak objection and strong objection in order to obtain useful information for clarification of social conflict on this issue. Results of polls of people who have weak agreement for nuclear technology reveal their ambivalence about nuclear technology. This raises concern that further implementation of nuclear technology might cause these people to shift their views to objection. (author)

  19. Educating for the Workplace through the Arts.

    Science.gov (United States)

    Getty Education Inst. for the Arts, Los Angeles, CA.

    Business leaders are increasingly realizing that arts education is beneficial in preparing young people for the workplace. Increasingly, business is acknowledging that arts education develops collaborative and teamwork skills, technological competencies, flexible thinking, and an appreciation for diversity. The need for imagination and creativity…

  20. Female age in ART : When to stop?

    NARCIS (Netherlands)

    Broekmans, FJ; Klinkert, ER

    2004-01-01

    With increasing age the probability of ongoing pregnancy established by the use of assisted reproduction technology ( ART) decreases. As a result the question arises whether age limits for the application of ART should be established. From a literature review and ongoing research data it appears

  1. Transformative art: art as means for long-term neurocognitive change.

    Science.gov (United States)

    Preminger, Son

    2012-01-01

    Every artwork leads to a unique experience by the observer or participant, may it be sensory, emotional, cognitive, interactive, or spiritual experience. At the neurobiological level, such experiences are manifested as activation of the corresponding neural networks. Neuroscience has demonstrated that experience, in particular repeated experience, can cause a long-term change in the involved brain circuits (experience-dependent plasticity). This review will discuss the molding and transformative aspect of arts, examining how repeated and on-going experience of arts may alter cognitive, emotional, and behavioral patterns as well as their underlying neural circuits. The application of this approach to cognitive training and neuropsychological rehabilitation methods will be addressed as well. In addition, it will be suggested that this approach to art, as a long-term transformative medium, may lead to a novel viewpoint on art and a different approach to its creation. Artists can design artworks that aspire to form, in addition to one-shot influencing experience, on-going experiences which gradually create a lasting change, possibly improving audiences' neuropsychological functions.

  2. Transformative Art:Art as Means for Long-term Neurocognitive Change

    Directory of Open Access Journals (Sweden)

    Son ePreminger

    2012-04-01

    Full Text Available Every artwork leads to a unique experience by the observer or participant, may it be sensory, emotional, cognitive, interactive or spiritual experience. At the neurobiological level, such experiences are manifested as activation of the corresponding neural networks. Neuroscience has demonstrated that experience, in particular repeated experience, can cause a long-term change in the involved brain circuits (experience-dependent plasticity. This review will discuss the molding and transformative aspect of arts, examining how repeated and on-going experience of arts may alter cognitive, emotional and behavioral patterns as well as their underlying neural circuits. The application of this approach to cognitive training and neuropsychological rehabilitation methods will be addressed as well. In addition, it will be suggested that this approach to art, as long-term transformative, may lead to a novel viewpoint on art and a different approach to its creation. Artists can design artworks that aspire to form, in addition to one-shot influencing experience, on-going experiences which gradually create a lasting change, possibly improving audiences' neuropsychological functions.

  3. Efficient thermal desalination technologies with renewable energy systems: A state-of-the-art review

    Energy Technology Data Exchange (ETDEWEB)

    Esfahani, Iman Janghorban; Rashidi, Jouan; Ifaei, Pouya; Yoo, ChangKyoo [Center for Environmental Studies, Kyung Hee University, Yongin (Korea, Republic of)

    2016-02-15

    Due to the current fossil fuel crisis and associated adverse environmental impacts, renewable energy sources (RES) have drawn interest as alternatives to fossil fuels for powering water desalination systems. Over the last few decades the utility of renewable energy sources such as solar, geothermal, and wind to run desalination processes has been explored. However, the expansion of these technologies to larger scales is hampered by techno-economic and thermo-economic challenges. This paper reviews the state-of-the-art in the field of renewable energy-powered thermal desalination systems (RE-PTD) to compare their productivity and efficiency through thermodynamic, economic, and environmental analyses. We performed a comparative study using published data to classify RE-PTD systems technologies on the basis of the energy collection systems that they use. Among RE-PTD systems, solar energy powered-thermal desalination systems demonstrate high thermo-environ-economic efficiency to produce fresh water to meet various scales of demand.

  4. Efficient thermal desalination technologies with renewable energy systems: A state-of-the-art review

    International Nuclear Information System (INIS)

    Esfahani, Iman Janghorban; Rashidi, Jouan; Ifaei, Pouya; Yoo, ChangKyoo

    2016-01-01

    Due to the current fossil fuel crisis and associated adverse environmental impacts, renewable energy sources (RES) have drawn interest as alternatives to fossil fuels for powering water desalination systems. Over the last few decades the utility of renewable energy sources such as solar, geothermal, and wind to run desalination processes has been explored. However, the expansion of these technologies to larger scales is hampered by techno-economic and thermo-economic challenges. This paper reviews the state-of-the-art in the field of renewable energy-powered thermal desalination systems (RE-PTD) to compare their productivity and efficiency through thermodynamic, economic, and environmental analyses. We performed a comparative study using published data to classify RE-PTD systems technologies on the basis of the energy collection systems that they use. Among RE-PTD systems, solar energy powered-thermal desalination systems demonstrate high thermo-environ-economic efficiency to produce fresh water to meet various scales of demand.

  5. Les dispositifs du Net art

    OpenAIRE

    Fourmentraux, Jean-Paul

    2010-01-01

    La pratique du Net art radicalise la question du potentiel communicationnel d’un média —Internet— qui constitue tout à la fois le support technique, l’outil créatif et le dispositif social de l’œuvre. Les technologies de l’information et de la communication (TIC) placent en effet l’œuvre d’art au cœur d’une négociation socialement distribuée entre l’artiste et le public. L’article est focalisé sur cette construction collective du Net art et sur ses mises en scènes. Il montre le travail artist...

  6. Establishment of database and network for research of stream generator and state of the art technology review

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jae Bong; Hur, Nam Su; Moon, Seong In; Seo, Hyeong Won; Park, Bo Kyu; Park, Sung Ho; Kim, Hyung Geun [Sungkyunkwan Univ., Seoul (Korea, Republic of)

    2004-02-15

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology.

  7. Establishment of database and network for research of stream generator and state of the art technology review

    International Nuclear Information System (INIS)

    Choi, Jae Bong; Hur, Nam Su; Moon, Seong In; Seo, Hyeong Won; Park, Bo Kyu; Park, Sung Ho; Kim, Hyung Geun

    2004-02-01

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology

  8. Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery.

    Directory of Open Access Journals (Sweden)

    Felipe Merino

    2015-06-01

    Full Text Available Highly specific transcriptional regulation depends on the cooperative association of transcription factors into enhanceosomes. Usually, their DNA-binding cooperativity originates from either direct interactions or DNA-mediated allostery. Here, we performed unbiased molecular simulations followed by simulations of protein-DNA unbinding and free energy profiling to study the cooperative DNA recognition by OCT4 and SOX2, key components of enhanceosomes in pluripotent cells. We found that SOX2 influences the orientation and dynamics of the DNA-bound configuration of OCT4. In addition SOX2 modifies the unbinding free energy profiles of both DNA-binding domains of OCT4, the POU specific and POU homeodomain, despite interacting directly only with the first. Thus, we demonstrate that the OCT4-SOX2 cooperativity is modulated by an interplay between protein-protein interactions and DNA-mediated allostery. Further, we estimated the change in OCT4-DNA binding free energy due to the cooperativity with SOX2, observed a good agreement with experimental measurements, and found that SOX2 affects the relative DNA-binding strength of the two OCT4 domains. Based on these findings, we propose that available interaction partners in different biological contexts modulate the DNA exploration routes of multi-domain transcription factors such as OCT4. We consider the OCT4-SOX2 cooperativity as a paradigm of how specificity of transcriptional regulation is achieved through concerted modulation of protein-DNA recognition by different types of interactions.

  9. Ratio-of-Mediator-Probability Weighting for Causal Mediation Analysis in the Presence of Treatment-by-Mediator Interaction

    Science.gov (United States)

    Hong, Guanglei; Deutsch, Jonah; Hill, Heather D.

    2015-01-01

    Conventional methods for mediation analysis generate biased results when the mediator--outcome relationship depends on the treatment condition. This article shows how the ratio-of-mediator-probability weighting (RMPW) method can be used to decompose total effects into natural direct and indirect effects in the presence of treatment-by-mediator…

  10. Vicious vs. Virtuous Cycles of Turn Negotiation in Video-Mediated Telecollaboration: Interactional Sociolinguistics Perspective

    Science.gov (United States)

    Akiyama, Yuka

    2016-01-01

    To examine how participants' different eTandem experiences could be attributed to the way they co-constructed turns, this study analyzed turn negotiation practices of one dyad who engaged in video-mediated interaction between Japan and America. This dyad was chosen for analysis because they expressed the greatest frustration and required a…

  11. Impact of technology-infused interactive learning environments on college professors' instructional decisions and practices

    Science.gov (United States)

    Kuda Malwathumullage, Chamathca Priyanwada

    Recent advancements in instructional technology and interactive learning space designs have transformed how undergraduate classrooms are envisioned and conducted today. Large number of research studies have documented the impact of instructional technology and interactive learning spaces on elevated student learning gains, positive attitudes, and increased student engagement in undergraduate classrooms across nation. These research findings combined with the movement towards student-centered instructional strategies have motivated college professors to explore the unfamiliar territories of instructional technology and interactive learning spaces. Only a limited number of research studies that explored college professors' perspective on instructional technology and interactive learning space use in undergraduate classrooms exist in the education research literature. Since college professors are an essential factor in undergraduate students' academic success, investigating how college professors perceive and utilize instructional technology and interactive learning environments can provide insights into designing effective professional development programs for college professors across undergraduate institutions. Therefore, the purpose of this study was to investigate college professors' pedagogical reasoning behind incorporating different types of instructional technologies and teaching strategies to foster student learning in technology-infused interactive learning environments. Furthermore, this study explored the extent to which college professors' instructional decisions and practices are affected by teaching in an interactive learning space along with their overall perception of instructional technology and interactive learning spaces. Four college professors from a large public Midwestern university who taught undergraduate science courses in a classroom based on the 'SCALE-UP model' participated in this study. Major data sources included classroom

  12. THE POSSIBILITY OF USING INFORMATION TECHNOLOGY IN THE PROCESS OF PROFESSIONAL SELF-DETERMINATION OF THE FUTURE EXPERT ARTS AND CULTURE

    Directory of Open Access Journals (Sweden)

    T. U. Medvedeva

    2015-01-01

    Full Text Available The article discusses the problem of formation of professionals in the field of art and culture, educational opportunities disclosed information technology. As an analytical sample of the material used job-producers for students to analyze practical classes on "Marketing, public relations and advertising in producing activities"

  13. Arte e Mí­dia: aproximações e distinções

    Directory of Open Access Journals (Sweden)

    Arlindo Machado

    2008-11-01

    technological means. Naturally, the techniques, the methods, the devices that the artist uses to conceive, construct and exhibit works of art are not mere inert tools, nor innocent means indifferent in regard to the results, which can be interchanged at will by any number of other means. They are charged with concepts, zthey have a history, they derive from well-defined productive conditions. The media arts, as any art strictly determined through technical means, present the artist with the permanent challenge of counterposing himself or herself against technological determinism, of refusing the preconfigured operative models built into the devices, thus assuring that the resulting artwork is not a mere endorsement of the objectives of productivity of the technological society. They delineate a clear border between what is, on the one hand, mere industrial production of agreeable designs for the mass media, and on the other, the search for an ethics and an aesthetics for the electronic era. Keywords media arts, mass media, technological mediation

  14. ARTE: French-German Experiments in Crossing the Borders. 'One Media – Three Screens' Convergence and Interactivity at its Full Potential?

    Directory of Open Access Journals (Sweden)

    Anna Wiehl

    2014-12-01

    Full Text Available This contribution aims at discussing policies of convergence as well as at questioning whether the current strategies really exploit the options of digital media to its full potential – especially with regard to transmedia-storytelling, interactivity, participation and networking. By the paradigm of the 'European Culture Channel' ARTE, we draw a sketch of the portfolio of existing and emerging new formats and user practices. In the second part, we examine one specific genre from this context: the web-or trans-media-documentary. Taking Prison Valley as a case study, we consider transformations on both the macro and the micro level. Eventually, we question whether ARTE fulfils its promise to be the first "100% bi-medial channel" (ARTE mission statement, or whether it promotes an 'extended side-by-sideness' of devices and practices – some first steps towards the synergetic potential of media convergence.

  15. Interactivity, Game Creation, Design, Learning, and Innovation

    DEFF Research Database (Denmark)

    This book constitutes the proceedings of two conferences: The 5th International Conference on ArtsIT, Interactivity and Game Creation (ArtsIT 2016) and the First International Conference on Design, Learning and Innovation (DLI 2016). ArtsIT is reflecting trends in the expanding field of digital art......, interactive art, and how game creation is considered an art form. The decision was made to augment the title of ArtsIT to be in future known as “The International Conference on Interactivity, Game Creation, Design, Learning, and Innovation”. The event was hosted in Esbjerg, Denmark in May 2016 and attracted...

  16. Promoting Art through Technology, Education and Research of Natural Sciences (PATTERNS) across Wyoming, A Wyoming NSF EPSCoR Funded Project

    Science.gov (United States)

    Gellis, B. S.; McElroy, B. J.

    2016-12-01

    PATTERNS across Wyoming is a science and art project that promotes new and innovative approaches to STEM education and outreach, helping to re-contextualize how educators think about creative knowledge, and how to reach diverse audiences through informal education. The convergence of art, science and STEM outreach efforts is vital to increasing the presence of art in geosciences, developing multidisciplinary student research opportunities, expanding creative STEM thinking, and generating creative approaches of visualizing scientific data. A major goal of this project is to train art students to think critically about the value of scientific and artistic inquiry. PATTERNS across Wyoming makes science tangible to Wyoming citizens through K-14 art classrooms, and promotes novel maker-based art explorations centered around Wyoming's geosciences. The first PATTERNS across Wyoming scientific learning module (SIM) is a fish-tank sized flume that recreates natural patterns in sand as a result of fluid flow and sediment transport. It will help promotes the understanding of river systems found across Wyoming (e.g. Green, Yellowstone, Snake). This SIM, and the student artwork inspired by it, will help to visualize environmental-water changes in the central Rocky Mountains and will provide the essential inspiration and tools for Wyoming art students to design biological-driven creative explorations. Each art class will receive different fluvial system conditions, allowing for greater understanding of river system interactions. Artwork will return to the University of Wyoming for a STE{A}M Exhibition inspired by Wyoming's varying fluvial systems. It is our hope that new generations of science and art critical thinkers will not only explore questions of `why' and `how' scientific phenomena occur, but also `how' to better predict, conserve and study invaluable artifacts, and visualize conditions which allow for better control of scientific outcomes and public understanding.

  17. Wearing embodied emotions a practice based design research on wearable technology

    CERN Document Server

    Ugur, Seçil

    2013-01-01

    Today, people are in an era of digitally mediated Human-to-Human Interaction, which cannot provide full sensorial contact and therefore, emotions cannot be communicated completely. The intimate cover of the human body, i.e. garment is the interface, where many personal traits are embodied. With the improvements in textile and electronics industry, this embodiment can be carried on a higher level, where the garments become dynamic interfaces and extensions of the human body. This book consists of a research on skin, clothes and technology as extensions of human body, emotions, technology-mediat

  18. Narrative in young children’s digital art-making

    OpenAIRE

    Sakr, Mona; Connelly, Vince; Wild, Mary

    2016-01-01

    Digital technologies have material and social properties that have the potential to create new opportunities for children’s expressive arts practices. The presence and development of oral narratives in young children’s visual art-making on paper has been noted in previous research, but little is known about the narratives children create when they engage in digital art-making. How do young children construct narratives during digital art-making? How do the features of these narratives relate ...

  19. The Benefits of Social Technology Use Among Older Adults Are Mediated by Reduced Loneliness

    Science.gov (United States)

    2016-01-01

    Abstract Technology has the ability to enhance and enrich the lives of older adults by facilitating better interpersonal relationships. However, few studies have directly examined associations between technology use for social reasons and physical and psychological health among older adults. The current study examines the benefits of technology use in 591 older adults from the 2012 wave of the Health and Retirement Study (Mage = 68.18, SD = 10.75; 55.5% female). Social technology use was assessed through five technology-based behaviors (i.e., using e-mail, social networking sites, online video/phone calls, online chatting/instant messaging, using a smartphone). Attitudes toward the usability and benefits of technology use were also assessed. Older adults had generally positive attitudes toward technology. Higher social technology use was associated with better self-rated health, fewer chronic illnesses, higher subjective well-being, and fewer depressive symptoms. Furthermore, each of the links between social technology use and physical and psychological health was mediated by reduced loneliness. Close relationships are a large determinant of physical health and well-being, and technology has the potential to cultivate successful relationships among older adults. PMID:27541746

  20. The Benefits of Social Technology Use Among Older Adults Are Mediated by Reduced Loneliness.

    Science.gov (United States)

    Chopik, William J

    2016-09-01

    Technology has the ability to enhance and enrich the lives of older adults by facilitating better interpersonal relationships. However, few studies have directly examined associations between technology use for social reasons and physical and psychological health among older adults. The current study examines the benefits of technology use in 591 older adults from the 2012 wave of the Health and Retirement Study (Mage = 68.18, SD = 10.75; 55.5% female). Social technology use was assessed through five technology-based behaviors (i.e., using e-mail, social networking sites, online video/phone calls, online chatting/instant messaging, using a smartphone). Attitudes toward the usability and benefits of technology use were also assessed. Older adults had generally positive attitudes toward technology. Higher social technology use was associated with better self-rated health, fewer chronic illnesses, higher subjective well-being, and fewer depressive symptoms. Furthermore, each of the links between social technology use and physical and psychological health was mediated by reduced loneliness. Close relationships are a large determinant of physical health and well-being, and technology has the potential to cultivate successful relationships among older adults.