WorldWideScience

Sample records for techniques specific applications

  1. Industrial application of domain specific languages combined with formal techniques

    NARCIS (Netherlands)

    Schuts, M.; Hooman, J.

    2016-01-01

    Two Domain Specific Languages (DSLs) have been developed to improve the development of a power control component of interventional X-ray systems of Philips. Configuration files and test cases are generated from instances of these DSLs. To increase the confidence in these instances and the generators

  2. A fast and robust patient specific Finite Element mesh registration technique: application to 60 clinical cases

    CERN Document Server

    Bucki, Marek; Payan, Yohan; 10.1016/j.media.2010.02.003

    2010-01-01

    Finite Element mesh generation remains an important issue for patient specific biomechanical modeling. While some techniques make automatic mesh generation possible, in most cases, manual mesh generation is preferred for better control over the sub-domain representation, element type, layout and refinement that it provides. Yet, this option is time consuming and not suited for intraoperative situations where model generation and computation time is critical. To overcome this problem we propose a fast and automatic mesh generation technique based on the elastic registration of a generic mesh to the specific target organ in conjunction with element regularity and quality correction. This Mesh-Match-and-Repair (MMRep) approach combines control over the mesh structure along with fast and robust meshing capabilities, even in situations where only partial organ geometry is available. The technique was successfully tested on a database of 5 pre-operatively acquired complete femora CT scans, 5 femoral heads partially...

  3. A Study of Applications of Multiagent System Specifications and the Key Techniques in Automatic Abstracts System

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In this thesis, multiagent system specifications, multiagent system architecture s , agent communication languages and agent communication protocols, automatic abs tracting based on multiagent technologies are studied. Some concerned problems o f designs and realization of automatic abstracting systems based on multiagent t echnologies are studied, too. Chapter 1 shows the significance and objectives of the thesis, its main contents are summarized, and innovations of the thesis are showed. Some basic concepts of agents and multiagent systems are studied in Cha pter 2. The definitions of agents and multiagent systems are given, and the theo ry, technologies and applications of multiagent systems are summarized. Furtherm ore, some important studying trends of multiagent systems are set forward. Multi agent system specifications are studied in Chapter 3. MAS/KIB—a multiagent syst em specification is built using mental states such as K(Know), B(Belief) , and I(Intention), its grammar and semanteme are discussed, axioms and infe rence rules are given, and some properties are researched. We also compare MAS/K IB with other existing specifications. MAS/KIB has the following characteristics : (1) each agent has its own world outlook; (2) no global data in the system; (3 ) processes of state changes are used as indexes to systems; (4) it has the char acteristics of not only time series logic but also dynamic logic; and (5) intera ctive actions are included. The architectures of multiagent systems are studied in Chapter 4. First, we review some typical architecture of multiagent systems, agent network architecture, agent federated architecture, agent blackboard archi tecture, and Foundation of Intelligent Physical Agent(FIPA) architecture. For th e first time, we set forward and study the layering and partitioning models of t he architectures of multiagent systems, organizing architecture models, and inte roperability architecture model of multiagent

  4. Brachytherapy applications and techniques

    CERN Document Server

    Devlin, Phillip M

    2015-01-01

    Written by the foremost experts in the field, this volume is a comprehensive text and practical reference on contemporary brachytherapy. The book provides detailed, site-specific information on applications and techniques of brachytherapy in the head and neck, central nervous system, breast, thorax, gastrointestinal tract, and genitourinary tract, as well as on gynecologic brachytherapy, low dose rate and high dose rate sarcoma brachytherapy, vascular brachytherapy, and pediatric applications. The book thoroughly describes and compares the four major techniques used in brachytherapy-intraca

  5. A Way Memoization Technique for Reducing Power Consumption of Caches in Application Specific Integrated Processors

    CERN Document Server

    Ishihara, Tohru

    2011-01-01

    This paper presents a technique for eliminating redundant cache-tag and cache-way accesses to reduce power consumption. The basic idea is to keep a small number of Most Recently Used (MRU) addresses in a Memory Address Buffer (MAB) and to omit redundant tag and way accesses when there is a MAB-hit. Since the approach keeps only tag and set-index values in the MAB, the energy and area overheads are relatively small even for a MAB with a large number of entries. Furthermore, the approach does not sacrifice the performance. In other words, neither the cycle time nor the number of executed cycles increases. The proposed technique has been applied to Fujitsu VLIW processor (FR-V) and its power saving has been estimated using NanoSim. Experiments for 32kB 2-way set associative caches show the power consumption of I-cache and D-cache can be reduced by 40% and 50%, respectively.

  6. Techniques for Wireless Applications

    KAUST Repository

    Gaaloul, Fakhreddine

    2012-05-01

    Switching techniques have been first proposed as a spacial diversity techniques. These techniques have been shown to reduce considerably the processing load while letting multi-antenna systems achieve a specific target performance. In this thesis, we take a different look at the switching schemes by implementing them for different other wireless applications. More specifically, this thesis consists of three main parts, where the first part considers a multiuser environment and an adaptive scheduling algorithm based on the switching with post-selection scheme for statistically independent but non-identically distributed channel conditions. The performance of this switched based scheduler is investigated and a multitude of performance metrics are presented. In a second part, we propose and analyze the performance of three switched-based algorithms for interference reduction in the downlink of over-loaded femtocells. For instance, performance metrics are derived in closed-form and these metrics are used to compare these three proposed schemes. Finally in a third part, a switch based opportunistic channel access scheme is proposed for a cognitive radio system and its performance is analyzed in terms of two new proposed metrics namely the average cognitive radio access and the waiting time duration.

  7. Application of decision-tree technique to assess herd specific risk factors for coliform mastitis in sows

    Directory of Open Access Journals (Sweden)

    Imke Gerjets

    2011-06-01

    Full Text Available The aim of the study was to investigate factors associated with coliform mastitis in sows, determined at herd level, by applying the decision-tree technique. Coliform mastitis represents an economically important disease in sows after farrowing that also affects the health, welfare and performance of the piglets. The decision-tree technique, a data mining method, may be an effective tool for making large datasets accessible and different sow herd information comparable. It is based on the C4.5-algorithm which generates trees in a top-down recursive strategy. The technique can be used to detect weak points in farm management. Two datasets of two farms in Germany, consisting of sow-related parameters, were analysed and compared by decision-tree algorithms. Data were collected over the period of April 2007 to August 2010 from 987 sows (499 CM-positive sows and 488 CM-negative sows and 596 sows (322 CM-positive sows and 274 CM-negative sows, respectively. Depending on the dataset, different graphical trees were built showing relevant factors at the herd level which may lead to coliform mastitis. To our understanding, this is the first time decision-tree modeling was used to assess risk factors for coliform mastitis. Herd specific risk factors for the disease were illustrated what could prove beneficial in disease and herd management.

  8. APPLICATION OF NUCLEAR TECHNIQUE

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    1 Application of Fission Track Technique in Stratigraphy Guo Shilun Hao Xiuhong Chen Baoliu Huang Weiwen (Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China) Laterite (red soil) is distributed in the south of China from Qinling mountains to Hainan province and extends to Southeast Asia. The age of the formation and deposition of the laterite is an important subject in geological research. Due to lack of fossils of ancient animals and plants, as well as other objects which could be used for dating , the age of the laterite and its related stratum is unknown in the south of China.

  9. Application of an Impedimetric Technique for the Detection of Lytic Infection of Salmonella spp. by Specific Phages

    Directory of Open Access Journals (Sweden)

    Lara R. P. Amorim

    2009-01-01

    Full Text Available This study was performed to evaluate the adaption of the impedimetric method to detect the lytic infection by Salmonella-specific bacteriophages and to provide a higher selectivity to this rapid method in detecting Salmonella spp. by using specific agents. Three bacteriophages and twelve strains of Salmonella spp. were tested. Each of the twelve strains was used separately to inoculate TSB together with each one of the phages. The inoculum concentration was between 106 and 107 cfu/mL, at a cell: phage ratio of 1 : 100. From the sample analysis, based on conductance (G measurements (37°C, the infection could be detected, by observation of both detection-time delay and distinct curve trends. The main conclusions were that kinetic detection by impedance microbiology with phage typing constitutes a method of determining whether a test microorganism is sensitive to the bacteriophage and a method to evaluate whether a lytic bacteriophage is present in a sample, by affecting bacterial growth rate/metabolic change.

  10. Some Approaches for Integration of Specification Techniques

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2000-01-01

    It is often useful to apply several specification techniques within the same software development project. This raises the question how specification techniques can be integrated. In this presentation we give three different examples of how this can be done. In the first example, we summarise how...

  11. Application of surface plasmon resonance for the detection of carbohydrates, glycoconjugates, and measurement of the carbohydrate-specific interactions: a comparison with conventional analytical techniques. A critical review.

    Science.gov (United States)

    Safina, Gulnara

    2012-01-27

    Carbohydrates (glycans) and their conjugates with proteins and lipids contribute significantly to many biological processes. That makes these compounds important targets to be detected, monitored and identified. The identification of the carbohydrate content in their conjugates with proteins and lipids (glycoforms) is often a challenging task. Most of the conventional instrumental analytical techniques are time-consuming and require tedious sample pretreatment and utilising various labeling agents. Surface plasmon resonance (SPR) has been intensively developed during last two decades and has received the increasing attention for different applications, from the real-time monitoring of affinity bindings to biosensors. SPR does not require any labels and is capable of direct measurement of biospecific interaction occurring on the sensing surface. This review provides a critical comparison of modern analytical instrumental techniques with SPR in terms of their analytical capabilities to detect carbohydrates, their conjugates with proteins and lipids and to study the carbohydrate-specific bindings. A few selected examples of the SPR approaches developed during 2004-2011 for the biosensing of glycoforms and for glycan-protein affinity studies are comprehensively discussed.

  12. Statistical and Economic Techniques for Site-specific Nematode Management.

    Science.gov (United States)

    Liu, Zheng; Griffin, Terry; Kirkpatrick, Terrence L

    2014-03-01

    Recent advances in precision agriculture technologies and spatial statistics allow realistic, site-specific estimation of nematode damage to field crops and provide a platform for the site-specific delivery of nematicides within individual fields. This paper reviews the spatial statistical techniques that model correlations among neighboring observations and develop a spatial economic analysis to determine the potential of site-specific nematicide application. The spatial econometric methodology applied in the context of site-specific crop yield response contributes to closing the gap between data analysis and realistic site-specific nematicide recommendations and helps to provide a practical method of site-specifically controlling nematodes.

  13. Photogrammetric techniques for aerospace applications

    Science.gov (United States)

    Liu, Tianshu; Burner, Alpheus W.; Jones, Thomas W.; Barrows, Danny A.

    2012-10-01

    Photogrammetric techniques have been used for measuring the important physical quantities in both ground and flight testing including aeroelastic deformation, attitude, position, shape and dynamics of objects such as wind tunnel models, flight vehicles, rotating blades and large space structures. The distinct advantage of photogrammetric measurement is that it is a non-contact, global measurement technique. Although the general principles of photogrammetry are well known particularly in topographic and aerial survey, photogrammetric techniques require special adaptation for aerospace applications. This review provides a comprehensive and systematic summary of photogrammetric techniques for aerospace applications based on diverse sources. It is useful mainly for aerospace engineers who want to use photogrammetric techniques, but it also gives a general introduction for photogrammetrists and computer vision scientists to new applications.

  14. Geolocation Techniques Principles and Applications

    CERN Document Server

    Gentile, Camillo; Raulefs, Ronald; Teolis, Carole

    2013-01-01

    Geolocation Techniques: Principles and Applications provides a comprehensive overview of geolocation technologies and techniques, from radio-frequency based to inertial based. The focus of this book is to provide an overview on the different types of infra-structure supported by most commercial localization systems as well as on the most popular computational techniques which these systems employ. This book can serve as a reference for scholarly activities such as teaching, self-learning, or research.

  15. Principled Variance Reduction Techniques for Real Time Patient-Specific Monte Carlo Applications within Brachytherapy and Cone-Beam Computed Tomography

    Science.gov (United States)

    Sampson, Andrew Joseph

    This dissertation describes the application of two principled variance reduction strategies to increase the efficiency for two applications within medical physics. The first, called correlated Monte Carlo (CMC) applies to patient-specific, permanent-seed brachytherapy (PSB) dose calculations. The second, called adjoint-biased forward Monte Carlo (ABFMC), is used to compute cone-beam computed tomography (CBCT) scatter projections. CMC was applied for two PSB cases: a clinical post-implant prostate, and a breast with a simulated lumpectomy cavity. CMC computes the dose difference, DeltaD, between the highly correlated dose computing homogeneous and heterogeneous geometries. The particle transport in the heterogeneous geometry assumed a purely homogeneous environment, and altered particle weights accounted for bias. Average gains of 37 to 60 are reported from using CMC, relative to un-correlated Monte Carlo (UMC) calculations, for the prostate and breast CTV's, respectively. To further increase the efficiency up to 1500 fold above UMC, an approximation called interpolated correlated Monte Carlo (ICMC) was applied. ICMC computes DeltaD using CMC on a low-resolution (LR) spatial grid followed by interpolation to a high-resolution (HR) voxel grid followed. The interpolated, HR DeltaD is then summed with a HR, pre-computed, homogeneous dose map. ICMC computes an approximate, but accurate, HR heterogeneous dose distribution from LR MC calculations achieving an average 2% standard deviation within the prostate and breast CTV's in 1.1 sec and 0.39 sec, respectively. Accuracy for 80% of the voxels using ICMC is within 3% for anatomically realistic geometries. Second, for CBCT scatter projections, ABFMC was implemented via weight windowing using a solution to the adjoint Boltzmann transport equation computed either via the discrete ordinates method (DOM), or a MC implemented forward-adjoint importance generator (FAIG). ABFMC, implemented via DOM or FAIG, was tested for a

  16. Principles, techniques, and applications of biocatalyst immobilization for industrial application.

    Science.gov (United States)

    Eş, Ismail; Vieira, José Daniel Gonçalves; Amaral, André Corrêa

    2015-03-01

    Immobilization is one of the most effective and powerful tools used in industry, which has been studied and improved since the last century. Various immobilization techniques and support materials have been used on both laboratory and industrial scale. Each immobilization technique is applicable for a specific production mostly depending on the cost and sensibility of process. Compared to free biocatalyst systems, immobilization techniques often offer better stability, increased activity and selectivity, higher resistance, improved separation and purification, reuse of enzymes, and consequently more efficient process. Recently, many reviews have been published about immobilization systems; however, most of them have focused on a specific application or not emphasized in details. This review focuses on most commonly used techniques in industry with many recent applications including using bioreactor systems for industrial production. It is also aimed to emphasize the advantages and disadvantages of the immobilization techniques and how these systems improve process productivity compared to non-immobilized systems.

  17. Myositis specific autoantibodies : specificity and clinical applications

    NARCIS (Netherlands)

    Hengstman, G.J.D.

    2005-01-01

    The sera of about half of the patients with myositis contain autoantibodies that are specific for this group of diseases compared to other inflammatory connective tissue disorders. In a recent study we showed that these myositis specific autoantibodies (MSAs) are also specific for myositis as compar

  18. Myositis specific autoantibodies : specificity and clinical applications

    NARCIS (Netherlands)

    Hengstman, G.J.D.

    2005-01-01

    The sera of about half of the patients with myositis contain autoantibodies that are specific for this group of diseases compared to other inflammatory connective tissue disorders. In a recent study we showed that these myositis specific autoantibodies (MSAs) are also specific for myositis as compar

  19. Mining software specifications methodologies and applications

    CERN Document Server

    Lo, David

    2011-01-01

    An emerging topic in software engineering and data mining, specification mining tackles software maintenance and reliability issues that cost economies billions of dollars each year. The first unified reference on the subject, Mining Software Specifications: Methodologies and Applications describes recent approaches for mining specifications of software systems. Experts in the field illustrate how to apply state-of-the-art data mining and machine learning techniques to address software engineering concerns. In the first set of chapters, the book introduces a number of studies on mining finite

  20. Pinch Technique: Theory and Applications

    CERN Document Server

    Binosi, D; 10.1016/j.physrep.2009.05.001

    2009-01-01

    We review the theoretical foundations and most important physical applications of the Pinch Technique (PT). This method allows the construction of off-shell Green's functions in non-Abelian gauge theories that are independent of the gauge-fixing parameter and satisfy ghost-free Ward identities. We first present the diagrammatic formulation of the technique in QCD, deriving at one loop the gauge independent gluon self-energy, quark-gluon vertex, and three-gluon vertex, together with their Abelian Ward identities. The generalization to theories with spontaneous symmetry breaking is carried out in detail, and the connection with the optical theorem and the dispersion relations are explained within the electroweak sector of the Standard Model. The equivalence between the PT and the Feynman gauge of the Background Field Method (BFM) is elaborated, and the crucial differences between the two methods are critically scrutinized. The Batalin-Vilkovisky quantization method and the general formalism of algebraic renorma...

  1. Raman Imaging Techniques and Applications

    CERN Document Server

    2012-01-01

    Raman imaging has long been used to probe the chemical nature of a sample, providing information on molecular orientation, symmetry and structure with sub-micron spatial resolution. Recent technical developments have pushed the limits of micro-Raman microscopy, enabling the acquisition of Raman spectra with unprecedented speed, and opening a pathway to fast chemical imaging for many applications from material science and semiconductors to pharmaceutical drug development and cell biology, and even art and forensic science. The promise of tip-enhanced raman spectroscopy (TERS) and near-field techniques is pushing the envelope even further by breaking the limit of diffraction and enabling nano-Raman microscopy.

  2. Multimedia watermarking techniques and applications

    CERN Document Server

    Kirovski, Darko

    2006-01-01

    Intellectual property owners must continually exploit new ways of reproducing, distributing, and marketing their products. However, the threat of piracy looms as a major problem with digital distribution and storage technologies. Multimedia Watermarking Techniques and Applications covers all current and future trends in the design of modern systems that use watermarking to protect multimedia content. Containing the works of contributing authors who are worldwide experts in the field, this volume is intended for researchers and practitioners, as well as for those who want a broad understanding

  3. Pinch technique: Theory and applications

    Science.gov (United States)

    Binosi, Daniele; Papavassiliou, Joannis

    2009-08-01

    We review the theoretical foundations and the most important physical applications of the Pinch Technique (PT). This general method allows the construction of off-shell Green’s functions in non-Abelian gauge theories that are independent of the gauge-fixing parameter and satisfy ghost-free Ward identities. We first present the diagrammatic formulation of the technique in QCD, deriving, at one loop, the gauge independent gluon self-energy, quark-gluon vertex, and three-gluon vertex, together with their Abelian Ward identities. The generalization of the PT to theories with spontaneous symmetry breaking is carried out in detail, and the profound connection with the optical theorem and the dispersion relations are explained within the electroweak sector of the Standard Model. The equivalence between the PT and the Feynman gauge of the Background Field Method (BFM) is elaborated, and the crucial differences between the two methods are critically scrutinized. A variety of field theoretic techniques needed for the generalization of the PT to all orders are introduced, with particular emphasis on the Batalin-Vilkovisky quantization method and the general formalism of algebraic renormalization. The main conceptual and technical issues related to the extension of the technique beyond one loop are described, using the two-loop construction as a concrete example. Then the all-order generalization is thoroughly examined, making extensive use of the field theoretic machinery previously introduced; of central importance in this analysis is the demonstration that the PT-BFM correspondence persists to all orders in perturbation theory. The extension of the PT to the non-perturbative domain of the QCD Schwinger-Dyson equations is presented systematically, and the main advantages of the resulting self-consistent truncation scheme are discussed. A plethora of physical applications relying on the PT are finally reviewed, with special emphasis on the definition of gauge

  4. Principles, Techniques, and Applications of Tissue Microfluidics

    Science.gov (United States)

    Wade, Lawrence A.; Kartalov, Emil P.; Shibata, Darryl; Taylor, Clive

    2011-01-01

    The principle of tissue microfluidics and its resultant techniques has been applied to cell analysis. Building microfluidics to suit a particular tissue sample would allow the rapid, reliable, inexpensive, highly parallelized, selective extraction of chosen regions of tissue for purposes of further biochemical analysis. Furthermore, the applicability of the techniques ranges beyond the described pathology application. For example, they would also allow the posing and successful answering of new sets of questions in many areas of fundamental research. The proposed integration of microfluidic techniques and tissue slice samples is called "tissue microfluidics" because it molds the microfluidic architectures in accordance with each particular structure of each specific tissue sample. Thus, microfluidics can be built around the tissues, following the tissue structure, or alternatively, the microfluidics can be adapted to the specific geometry of particular tissues. By contrast, the traditional approach is that microfluidic devices are structured in accordance with engineering considerations, while the biological components in applied devices are forced to comply with these engineering presets.

  5. Risk based technique for improving technical specifications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, I. S.; Jae, M. S.; Kim, B. S.; Hwang, S. W.; Kang, K. M.; Park, S. S.; Yu, Y. S. [Hanyang Univ., Seoul (Korea, Republic of)

    2001-03-15

    The objective of this study is to develop the systematic guidance for reviewing the documents associated with the changes of technical specifications. The work done in this fiscal year is the following : surveys in TS requirements, TS improvements and TS regulations in foreign countries as well as Korea, surveys on the state-of-the-art of RITSs and their use in Korea, development of a decision-making framework for both the licensee and the regulation agency, description of risk measures, assessment methodology on STI/AOT, and adverse effects caused by periodic maintenance, which are explained in appendix. The results of this study might contribute to enhancing the quality of the current technical specifications and contribute to preparing the risk informed regulation program using the decision-making framework developed in this study.

  6. Aerospace management techniques: Commercial and governmental applications

    Science.gov (United States)

    Milliken, J. G.; Morrison, E. J.

    1971-01-01

    A guidebook for managers and administrators is presented as a source of useful information on new management methods in business, industry, and government. The major topics discussed include: actual and potential applications of aerospace management techniques to commercial and governmental organizations; aerospace management techniques and their use within the aerospace sector; and the aerospace sector's application of innovative management techniques.

  7. ANALYSIS OF RELATIONS BETWEEN JUDO TECHNIQUES AND SPECIFIC MOTOR ABILITIES

    Directory of Open Access Journals (Sweden)

    Patrik Drid

    2006-06-01

    Full Text Available Specific physical preparation affects the development of motor abilities required for execution of specific movements in judo. When selecting proper specific exercises for judo for a target motor ability, it is necessary to precede it with the study of the structure of specific judo techniques and activities of individual muscle groups engaged for execution of the technique. On the basis of this, one can understand which muscles are most engaged during realization of individual techniques, which serves as a standpoint for selection of a particular complex of specific exercises to produce the highest effects. In addition to the development of particular muscle groups, the means of specific preparation will take effect on the development of those motor abilities which are evaluated as the indispensable for the development of particular qualities which are characteristic for judo. This paper analyses the relationship between judo techniques field and specific motor abilities.

  8. An ASIC Low Power Primer Analysis, Techniques and Specification

    CERN Document Server

    Chadha, Rakesh

    2013-01-01

    This book provides an invaluable primer on the techniques utilized in the design of low power digital semiconductor devices.  Readers will benefit from the hands-on approach which starts form the ground-up, explaining with basic examples what power is, how it is measured and how it impacts on the design process of application-specific integrated circuits (ASICs).  The authors use both the Unified Power Format (UPF) and Common Power Format (CPF) to describe in detail the power intent for an ASIC and then guide readers through a variety of architectural and implementation techniques that will help meet the power intent.  From analyzing system power consumption, to techniques that can employed in a low power design, to a detailed description of two alternate standards for capturing the power directives at various phases of the design, this book is filled with information that will give ASIC designers a competitive edge in low-power design. Starts from the ground-up and explains what power is, how it is measur...

  9. ELECTRICAL TECHNIQUES FOR ENGINEERING APPLICATIONS.

    Science.gov (United States)

    Bisdorf, Robert J.

    1985-01-01

    Surface electrical geophysical methods have been used in such engineering applications as locating and delineating shallow gravel deposits, depth to bedrock, faults, clay zones, and other geological phenomena. Other engineering applications include determining water quality, tracing ground water contaminant plumes and locating dam seepages. Various methods and electrode arrays are employed to solve particular geological problems. The sensitivity of a particular method or electrode array depends upon the physics on which the method is based, the array geometry, the electrical contrast between the target and host materials, and the depth to the target. Each of the available electrical methods has its own particular advantages and applications which the paper discusses.

  10. Principles, Techniques, and Applications of Tissue Microfluidics

    Science.gov (United States)

    Wade, Lawrence A.; Kartalov, Emil P.; Shibata, Darryl; Taylor, Clive

    2011-01-01

    The principle of tissue microfluidics and its resultant techniques has been applied to cell analysis. Building microfluidics to suit a particular tissue sample would allow the rapid, reliable, inexpensive, highly parallelized, selective extraction of chosen regions of tissue for purposes of further biochemical analysis. Furthermore, the applicability of the techniques ranges beyond the described pathology application. For example, they would also allow the posing and successful answering of new sets of questions in many areas of fundamental research. The proposed integration of microfluidic techniques and tissue slice samples is called tissue microfluidics because it molds the microfluidic architectures in accordance with each particular structure of each specific tissue sample. Thus, microfluidics can be built around the tissues, following the tissue structure, or alternatively, the microfluidics can be adapted to the specific geometry of particular tissues. By contrast, the traditional approach is that microfluidic devices are structured in accordance with engineering considerations, while the biological components in applied devices are forced to comply with these engineering presets. The proposed principles represent a paradigm shift in microfluidic technology in three important ways: Microfluidic devices are to be directly integrated with, onto, or around tissue samples, in contrast to the conventional method of off-chip sample extraction followed by sample insertion in microfluidic devices. Architectural and operational principles of microfluidic devices are to be subordinated to suit specific tissue structure and needs, in contrast to the conventional method of building devices according to fluidic function alone and without regard to tissue structure. Sample acquisition from tissue is to be performed on-chip and is to be integrated with the diagnostic measurement within the same device, in contrast to the conventional method of off-chip sample prep and

  11. Application specific compression : final report.

    Energy Technology Data Exchange (ETDEWEB)

    Melgaard, David Kennett; Byrne, Raymond Harry; Myers, Daniel S.; Harrison, Carol D.; Lee, David S.; Lewis, Phillip J.; Carlson, Jeffrey J.

    2008-12-01

    With the continuing development of more capable data gathering sensors, comes an increased demand on the bandwidth for transmitting larger quantities of data. To help counteract that trend, a study was undertaken to determine appropriate lossy data compression strategies for minimizing their impact on target detection and characterization. The survey of current compression techniques led us to the conclusion that wavelet compression was well suited for this purpose. Wavelet analysis essentially applies a low-pass and high-pass filter to the data, converting the data into the related coefficients that maintain spatial information as well as frequency information. Wavelet compression is achieved by zeroing the coefficients that pertain to the noise in the signal, i.e. the high frequency, low amplitude portion. This approach is well suited for our goal because it reduces the noise in the signal with only minimal impact on the larger, lower frequency target signatures. The resulting coefficients can then be encoded using lossless techniques with higher compression levels because of the lower entropy and significant number of zeros. No significant signal degradation or difficulties in target characterization or detection were observed or measured when wavelet compression was applied to simulated and real data, even when over 80% of the coefficients were zeroed. While the exact level of compression will be data set dependent, for the data sets we studied, compression factors over 10 were found to be satisfactory where conventional lossless techniques achieved levels of less than 3.

  12. Micro manufacturing techniques and applications

    CERN Document Server

    Du, Ruxu; Li, Zifu

    2013-01-01

    Micro/meso-scale manufacturing has been developed in research fields of machining, forming, materials and others, but its potential to industries are yet to be fully realized. The theme of the current volume was to build a bridge joining academic research and industrial needs in micro manufacturing. Among the 12 papers selected for publication are three keynote addresses onmicro and desktop factories for micro/meso-scale manufacturing applicationsand future visions, tissue cutting mechanics and applications for needlecore biopsy and guidance, and micro-texturing onto amorphous carbonmaterials

  13. Image fusion theories, techniques and applications

    CERN Document Server

    Mitchell, HB

    2010-01-01

    This text provides a comprehensive introduction to the theories, techniques and applications of image fusion. It examines in detail many real-life examples of image fusion, including panchromatic sharpening and ensemble color image segmentation.

  14. Performability Modelling Tools, Evaluation Techniques and Applications

    NARCIS (Netherlands)

    Haverkort, Boudewijn R.H.M.

    1990-01-01

    This thesis deals with three aspects of quantitative evaluation of fault-tolerant and distributed computer and communication systems: performability evaluation techniques, performability modelling tools, and performability modelling applications. Performability modelling is a relatively new

  15. Development and applications of the IGISOL technique

    CERN Document Server

    Äystö, J

    2001-01-01

    The development and present status of the Ion Guide Isotope Separator On-Line technique is presented. Applications to nuclear physics research include decay spectroscopy of proton- and neutron-rich nuclei of refractory elements and studies of their ground-state properties by collinear laser spectroscopy. Future developments, including ion-beam manipulations by linear RFQ and Penning traps, are discussed together with high-energy applications of the IGISOL technique.

  16. TV content analysis techniques and applications

    CERN Document Server

    Kompatsiaris, Yiannis

    2012-01-01

    The rapid advancement of digital multimedia technologies has not only revolutionized the production and distribution of audiovisual content, but also created the need to efficiently analyze TV programs to enable applications for content managers and consumers. Leaving no stone unturned, TV Content Analysis: Techniques and Applications provides a detailed exploration of TV program analysis techniques. Leading researchers and academics from around the world supply scientifically sound treatment of recent developments across the related subject areas--including systems, architectures, algorithms,

  17. Interactive data visualization foundations, techniques, and applications

    CERN Document Server

    Ward, Matthew; Keim, Daniel

    2015-01-01

    Interactive Data Visualization: Foundations, Techniques, and Applications, Second Edition provides all the theory, details, and tools necessary to build visualizations and systems involving the visualization of data. In color throughout, it explains basic terminology and concepts, algorithmic and software engineering issues, and commonly used techniques and high-level algorithms. Full source code is provided for completing implementations.

  18. Language-parametric Techniques for Language-Specific Editors

    NARCIS (Netherlands)

    De Jonge, M.

    2014-01-01

    The goal of this dissertation is to develop techniques that simplify the implementation of tool support for new languages. More specifically, we focus on language-parametric solutions for the implementation of language-specific editor support. In the first part of this dissertation we investigate ge

  19. A Knowledge—Based Specification Technique for Protocol Development

    Institute of Scientific and Technical Information of China (English)

    张尧学; 史美林; 等

    1993-01-01

    is paper proposes a knowledge-based specification technique(KST)for protocol development.This technique semi-automatically translates a protocol described in an informal description(natural languages or graphs)into one described in forml specifications(Estells and SDL).The translation processes are suported by knowledge stored in the knowledge base.This paper discusses the concept,the specification control mechanism of KST and the rules and algorithms for production of FSM's which is the basis of Estelle and SDL.

  20. On specific features of investigation of fluid flows by photometric techniques

    Science.gov (United States)

    Vologdin, V. A.; Davydov, V. V.; Velichko, E. N.

    2016-08-01

    Specific features of investigation of the fluid flow structure in a pipeline by photometric techniques are considered. The applicability of the photometric techniques based on the Doppler effect to such studies is discussed. A new method for detecting defects on inner walls of a pipeline that involves the use of the laser radiation scattered from particles in a flowing fluid is suggested.

  1. A Survey of Structured and Object-Oriented Software Specification Methods and Techniques

    NARCIS (Netherlands)

    Wieringa, R.J.

    1998-01-01

    This article surveys techniques used in structured and object-oriented software specification methods. The techniques are classified as techniques for the specification of external interaction and internal decomposition. The external specification techniques are further subdivided into techniques fo

  2. Phase equilibria basic principles, applications, experimental techniques

    CERN Document Server

    Reisman, Arnold

    2013-01-01

    Phase Equilibria: Basic Principles, Applications, Experimental Techniques presents an analytical treatment in the study of the theories and principles of phase equilibria. The book is organized to afford a deep and thorough understanding of such subjects as the method of species model systems; condensed phase-vapor phase equilibria and vapor transport reactions; zone refining techniques; and nonstoichiometry. Physicists, physical chemists, engineers, and materials scientists will find the book a good reference material.

  3. Techniques and Applications of Urban Data Analysis

    KAUST Repository

    AlHalawani, Sawsan N.

    2016-05-26

    Digitization and characterization of urban spaces are essential components as we move to an ever-growing ’always connected’ world. Accurate analysis of such digital urban spaces has become more important as we continue to get spatial and social context-aware feedback and recommendations in our daily activities. Modeling and reconstruction of urban environments have thus gained unprecedented importance in the last few years. Such analysis typically spans multiple disciplines, such as computer graphics, and computer vision as well as architecture, geoscience, and remote sensing. Reconstructing an urban environment usually requires an entire pipeline consisting of different tasks. In such a pipeline, data analysis plays a strong role in acquiring meaningful insights from the raw data. This dissertation primarily focuses on the analysis of various forms of urban data and proposes a set of techniques to extract useful information, which is then used for different applications. The first part of this dissertation presents a semi-automatic framework to analyze facade images to recover individual windows along with their functional configurations such as open or (partially) closed states. The main advantage of recovering both the repetition patterns of windows and their individual deformation parameters is to produce a factored facade representation. Such a factored representation enables a range of applications including interactive facade images, improved multi-view stereo reconstruction, facade-level change detection, and novel image editing possibilities. The second part of this dissertation demonstrates the importance of a layout configuration on its performance. As a specific application scenario, I investigate the interior layout of warehouses wherein the goal is to assign items to their storage locations while reducing flow congestion and enhancing the speed of order picking processes. The third part of the dissertation proposes a method to classify cities

  4. Techniques and applications of path integration

    CERN Document Server

    Schulman, L S

    2005-01-01

    A book of techniques and applications, this text defines the path integral and illustrates its uses by example. It is suitable for advanced undergraduates and graduate students in physics; its sole prerequisite is a first course in quantum mechanics. For applications requiring specialized knowledge, the author supplies background material.The first part of the book develops the techniques of path integration. Topics include probability amplitudes for paths and the correspondence limit for the path integral; vector potentials; the Ito integral and gauge transformations; free particle and quadra

  5. Digital Holographic Microscopy Principles, Techniques, and Applications

    CERN Document Server

    Kim, Myung K

    2011-01-01

    Digital holography is an emerging field of new paradigm in general imaging applications. By replacing the photochemical procedures with electronic imaging and having a direct numerical access to the complex optical field, a wide range of new imaging capabilities become available, many of them difficult or infeasible in conventional holography. An increasing number of researchers—not only in optical physics and optical engineering, but also in diverse applications areas such as microbiology, medicine, marine science, particle analysis, microelectromechanics, and metrology—are realizing and exploiting the new capabilities of digital holography. Digital Holographic Microscopy: Principles, Techniques, and Applications, by Dr. Myung K. Kim, is intended to provide a brief but consistent introduction to the principles of digital holography as well as to give an organized overview of the large number of techniques and applications being developed. This will also shed some light on the range of possibilities for f...

  6. Immobilization Techniques for Microarray: Challenges and Applications

    Directory of Open Access Journals (Sweden)

    Satish Balasaheb Nimse

    2014-11-01

    Full Text Available The highly programmable positioning of molecules (biomolecules, nanoparticles, nanobeads, nanocomposites materials on surfaces has potential applications in the fields of biosensors, biomolecular electronics, and nanodevices. However, the conventional techniques including self-assembled monolayers fail to position the molecules on the nanometer scale to produce highly organized monolayers on the surface. The present article elaborates different techniques for the immobilization of the biomolecules on the surface to produce microarrays and their diagnostic applications. The advantages and the drawbacks of various methods are compared. This article also sheds light on the applications of the different technologies for the detection and discrimination of viral/bacterial genotypes and the detection of the biomarkers. A brief survey with 115 references covering the last 10 years on the biological applications of microarrays in various fields is also provided.

  7. Developing Communication Skills: General Considerations and Specific Techniques.

    Science.gov (United States)

    Joiner, Elizabeth Garner; Westphal, Patricia Barney, Ed.

    This practical book is designed for the classroom teacher of a second or foreign language at any level. The articles are grouped into two distinct but interdependent sections on general considerations and specific techniques. The contents of the first section are as follows: "Moi Tarzan, Vous Jane?: A Study of Communicative Competence" by P.B.…

  8. Progress in application of CFD techniques

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Computational Fluid Dynamics (CFD) is an important branch of fluid mechanics, and will continue to play great roles on the design of aerospace vehicles, explora- tion of new concept vehicles and new aerodynamic technology. This paper will present the progress of CFD from point of view of engineering application in recent years at CARDC, including the software integration, grid technique, speeding up of convergence, unsteady fluid computation,etc., and also give some engineering application examples of CFD at CARDC.

  9. Comparison of techniques for the detection of monocyte specific antigens.

    Science.gov (United States)

    Jager, M J; Thompson, J S; Claas, F H; Van Rood, J J

    1985-10-10

    Monocyte specific antigens are relevant in renal and bone marrow transplantation, but a reproducible monocyte-antigen system has not yet been recognized. In order to establish a sensitive test system with reproducible results in monocyte serology, 3 different monocyte cytotoxicity techniques were compared. In our hands the two-colour fluorescence test on post-Ficoll total leukocyte suspensions fulfilled the criteria. This technique was used to screen sera from multiparous women and renal transplant recipients for the presence of monocyte specific antibodies. By testing sera on cells from individuals who were HLA compatible with the serum donors, anti-HLA reactions were excluded. Several promising sera containing monocyte specific antibodies were identified, thus indicating the success of our approach.

  10. Audit Techniques for Service Oriented Architecture Applications

    Directory of Open Access Journals (Sweden)

    Liviu Adrian COTFAS

    2010-01-01

    Full Text Available The Service Oriented Architecture (SOA approach enables the development of flexible distributed applications. Auditing such applications implies several specific challenges related to interoperability, performance and security. The service oriented architecture model is described and the advantages of this approach are analyzed. We also highlight several quality attributes and potential risks in SOA applications that an architect should be aware when designing a distributed system. Key risk factors are identified and a model for risk evaluation is introduced. The top reasons for auditing SOA applications are presented as well as the most important standards. The steps for a successful audit process are given and discussed.

  11. Object recognition techniques in real applications

    NARCIS (Netherlands)

    Fernandez Robles, Laura

    2016-01-01

    This thesis proposes and evaluates object description and retrieval techniques in different real applications. First, we addressed the classification of boar spermatozoa according to acrosome integrity, which is an important challenge in the veterinary field. We presented several methods based on in

  12. Soft computing techniques in engineering applications

    CERN Document Server

    Zhong, Baojiang

    2014-01-01

    The Soft Computing techniques, which are based on the information processing of biological systems are now massively used in the area of pattern recognition, making prediction & planning, as well as acting on the environment. Ideally speaking, soft computing is not a subject of homogeneous concepts and techniques; rather, it is an amalgamation of distinct methods that confirms to its guiding principle. At present, the main aim of soft computing is to exploit the tolerance for imprecision and uncertainty to achieve tractability, robustness and low solutions cost. The principal constituents of soft computing techniques are probabilistic reasoning, fuzzy logic, neuro-computing, genetic algorithms, belief networks, chaotic systems, as well as learning theory. This book covers contributions from various authors to demonstrate the use of soft computing techniques in various applications of engineering.  

  13. Soft Computing Techniques for Process Control Applications

    Directory of Open Access Journals (Sweden)

    Rahul Malhotra

    2011-09-01

    Full Text Available Technological innovations in soft computing techniques have brought automation capabilities to new levelsof applications. Process control is an important application of any industry for controlling the complexsystem parameters, which can greatly benefit from such advancements. Conventional control theory isbased on mathematical models that describe the dynamic behaviour of process control systems. Due to lackin comprehensibility, conventional controllers are often inferior to the intelligent controllers. Softcomputing techniques provide an ability to make decisions and learning from the reliable data or expert’sexperience. Moreover, soft computing techniques can cope up with a variety of environmental and stabilityrelated uncertainties. This paper explores the different areas of soft computing techniques viz. Fuzzy logic,genetic algorithms and hybridization of two and abridged the results of different process control casestudies. It is inferred from the results that the soft computing controllers provide better control on errorsthan conventional controllers. Further, hybrid fuzzy genetic algorithm controllers have successfullyoptimized the errors than standalone soft computing and conventional techniques.

  14. Progress in application of CFD techniques

    Institute of Scientific and Technical Information of China (English)

    CHEN ZuoBin; JIANG Xiong; ZHOU Zhu; XIAO HanShan; HUANG Yong; MOU Bin; XIAO ZhongYun; LIU Gang; WANG YunTao

    2008-01-01

    Computational Fluid Dynamics (CFD) is an important branch of fluid mechanics,and will continue to play great roles on the design of aerospace vehicles,exploration of new concept vehicles and new aerodynamic technology.This paper will present the progress of CFD from point of view of engineering application in recent years at CARDC,including the software integration,grid technique,speeding up of convergence,unsteady fluid computation,etc.,and also give some engineering application examples of CFD at CARDC.

  15. Emerging wireless networks concepts, techniques and applications

    CERN Document Server

    Makaya, Christian

    2011-01-01

    An authoritative collection of research papers and surveys, Emerging Wireless Networks: Concepts, Techniques, and Applications explores recent developments in next-generation wireless networks (NGWNs) and mobile broadband networks technologies, including 4G (LTE, WiMAX), 3G (UMTS, HSPA), WiFi, mobile ad hoc networks, mesh networks, and wireless sensor networks. Focusing on improving the performance of wireless networks and provisioning better quality of service and quality of experience for users, it reports on the standards of different emerging wireless networks, applications, and service fr

  16. Microfluidic desalination techniques and their potential applications.

    Science.gov (United States)

    Roelofs, S H; van den Berg, A; Odijk, M

    2015-09-07

    In this review we discuss recent developments in the emerging research field of miniaturized desalination. Traditionally desalination is performed to convert salt water into potable water and research is focused on improving performance of large-scale desalination plants. Microfluidic desalination offers several new opportunities in comparison to macro-scale desalination, such as providing a platform to increase fundamental knowledge of ion transport on the nano- and microfluidic scale and new microfluidic sample preparation methods. This approach has also lead to the development of new desalination techniques, based on micro/nanofluidic ion-transport phenomena, which are potential candidates for up-scaling to (portable) drinking water devices. This review assesses microfluidic desalination techniques on their applications and is meant to contribute to further implementation of microfluidic desalination techniques in the lab-on-chip community.

  17. Multidirectional mobilities: Advanced measurement techniques and applications

    Science.gov (United States)

    Ivarsson, Lars Holger

    Today high noise-and-vibration comfort has become a quality sign of products in sectors such as the automotive industry, aircraft, components, households and manufacturing. Consequently, already in the design phase of products, tools are required to predict the final vibration and noise levels. These tools have to be applicable over a wide frequency range with sufficient accuracy. During recent decades a variety of tools have been developed such as transfer path analysis (TPA), input force estimation, substructuring, coupling by frequency response functions (FRF) and hybrid modelling. While these methods have a well-developed theoretical basis, their application combined with experimental data often suffers from a lack of information concerning rotational DOFs. In order to measure response in all 6 DOFs (including rotation), a sensor has been developed, whose special features are discussed in the thesis. This transducer simplifies the response measurements, although in practice the excitation of moments appears to be more difficult. Several excitation techniques have been developed to enable measurement of multidirectional mobilities. For rapid and simple measurement of the loaded mobility matrix, a MIMO (Multiple Input Multiple Output) technique is used. The technique has been tested and validated on several structures of different complexity. A second technique for measuring the loaded 6-by-6 mobility matrix has been developed. This technique employs a model of the excitation set-up, and with this model the mobility matrix is determined from sequential measurements. Measurements on ``real'' structures show that both techniques give results of similar quality, and both are recommended for practical use. As a further step, a technique for measuring the unloaded mobilities is presented. It employs the measured loaded mobility matrix in order to calculate compensation forces and moments, which are later applied in order to compensate for the loading of the

  18. Nonuniform sampling techniques for antenna applications

    Science.gov (United States)

    Rahmat-Samii, Yahya; Cheung, Rudolf Lap-Tung

    1987-01-01

    A two-dimensional sampling technique, which can employ irregularly spaced samples (amplitude and phase) in order to generate the complete far-field patterns is presented. The technique implements a matrix inversion algorithm, which depends only on the nonuniform sampled data point locations and with no dependence on the actual field values at these points. A powerful simulation algorithm is presented to allow a real-life simulation of many reflector/feed configurations and to determine the usefulness of the nonuniform sampling technique for the copolar and cross-polar patterns. Additionally, an overlapped window concept and a generalized error simulation model are discussed to identify the stability of the technique for recovering the field data among the nonuniform sampled data. Numerical results are tailored for the pattern reconstruction of a 20-m offset reflector antenna operating at L-band. This reflector is planned to be used in a proposed measurement concept of large antenna aboard the Space Shuttle, whereby it would be almost impractical to accurately control the movement of the Shuttle with respect to the RF source in prescribed directions in order to generate uniform sampled points. Also, application of the nonuniform sampling technique to patterns obtained using near-field measured data is demonstrated. Finally, results of an actual far-field measurement are presented for the construction of patterns of a reflector antenna from a set of nonuniformly distributed measured amplitude and phase data.

  19. Development of atom probe specimen preparation techniques for specific regions in steel materials.

    Science.gov (United States)

    Takahashi, Jun; Kawakami, Kazuto; Yamaguchi, Yukiko; Sugiyama, Masaaki

    2007-09-01

    More elaborated specimen preparation techniques for atom probe analysis were developed using a focused ion beam with a sample lift-out system so as to expand the application field in steel materials. The techniques enable atom probe analysis of sample steel at site-specific regions of interest. The preferable form of the needle specimen was provided by electrostatic field calculation using a finite element method. The new techniques were applied to the observation of a bainite-ferrite interface in a low carbon steel, and atomic-scale partitioning and segregation of alloying elements at the phase interface were directly observed in three dimensions.

  20. Interactive data visualization foundations, techniques, and applications

    CERN Document Server

    Ward, Matthew; Keim, Daniel

    2010-01-01

    Visualization is the process of representing data, information, and knowledge in a visual form to support the tasks of exploration, confirmation, presentation, and understanding. This book is designed as a textbook for students, researchers, analysts, professionals, and designers of visualization techniques, tools, and systems. It covers the full spectrum of the field, including mathematical and analytical aspects, ranging from its foundations to human visual perception; from coded algorithms for different types of data, information and tasks to the design and evaluation of new visualization techniques. Sample programs are provided as starting points for building one's own visualization tools. Numerous data sets have been made available that highlight different application areas and allow readers to evaluate the strengths and weaknesses of different visualization methods. Exercises, programming projects, and related readings are given for each chapter. The book concludes with an examination of several existin...

  1. Multimedia encryption and authentication techniques and applications

    CERN Document Server

    Furht, Borko

    2006-01-01

    Intellectual property owners must continually exploit new ways of reproducing, distributing, and marketing their products. However, the threat of piracy looms as a major problem with digital distribution and storage technologies. Multimedia Encryption and Authentication Techniques and Applications covers current and future trends in the design of modern systems that use encryption and authentication to protect multimedia content. Containing the works of contributing authors who are worldwide experts in their fields, this volume is intended for researchers and practitioners, as well as for thos

  2. Assessing Specific Sexual Behavior: Instrument Development and Validation Techniques.

    Science.gov (United States)

    Webb, Monica C; Chaney, J Don; Chen, W William; Dodd, Virginia J; Huang, I-Chan; Sanders, Sadie

    2015-02-01

    Through the use of multi-modal methods, the purpose of this study was to develop and assess measurement properties of an instrument evaluating specific sexual behaviors of college students and the role alcohol intoxication plays in one's intention to participate in these behaviors. A modified version of N. Krause's instrument development process was applied to create a behavior-specific instrument assessing oral, vaginal, and anal sex behaviors. The process included a review by expert scholars in relevant fields, cognitive interviews with the target population using screen-capture program Camtasia, piloting to assess measurement scales, and a formal investigation. The applied instrument development process employed screen capture software and web-based surveying in a cost-effective format suitable for mixed-method measurement development. The development and application of the instrument provides a clearer understanding of the relationship between alcohol use and sexual activity and aids in the development of effective public health interventions and policies.

  3. [Allele-specific PCR and its application in forensic science].

    Science.gov (United States)

    Nie, Yan-chai; Wang, Bin; Zhao, Zi-qin; Zhou, Huai-gu

    2014-08-01

    Allele-specific polymerase chain reaction (AS-PCR) is a technique based on allele-specific primers, which can be used to analyze single nucleotide polymorphism (SNP) effectively including the transition, transversion and insertion/deletion polymorphism and has been exploited in the study of diseases research, molecular diagnosis, and forensic biological evidence. The article systematically reviews the principle, the detection methods, improvement of AS-PCR, and its research updates in the fields of autosome, Y chromosome and mitochondrial SNP, as well as its application in forensic science.

  4. Application of Electromigration Techniques in Environmental Analysis

    Science.gov (United States)

    Bald, Edward; Kubalczyk, Paweł; Studzińska, Sylwia; Dziubakiewicz, Ewelina; Buszewski, Bogusław

    Inherently trace-level concentration of pollutants in the environment, together with the complexity of sample matrices, place a strong demand on the detection capabilities of electromigration methods. Significant progress is continually being made, widening the applicability of these techniques, mostly capillary zone electrophoresis, micellar electrokinetic chromatography, and capillary electrochromatography, to the analysis of real-world environmental samples, including the concentration sensitivity and robustness of the developed analytical procedures. This chapter covers the recent major developments in the domain of capillary electrophoresis analysis of environmental samples for pesticides, polycyclic aromatic hydrocarbons, phenols, amines, carboxylic acids, explosives, pharmaceuticals, and ionic liquids. Emphasis is made on pre-capillary and on-capillary chromatography and electrophoresis-based concentration of analytes and detection improvement.

  5. MR cholangiography: techniques and clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Pavone, P.; Laghi, A.; Panebianco, V.; Catalano, C.; Lobina, L.; Passariello, R. [Department of Radiology, University of Rome (Italy)

    1998-07-01

    Magnetic resonance cholangiography (MRCP) is a new non-invasive imaging technique for the evaluation of bilio-pancreatic disorders. Different sequences, using both breathhold and non-breathhold techniques, have been employed in order to obtain MRCP images. The authors discuss the technical aspects, particularly focusing their attention on a non-breathhold, three-dimensional, fat-suppressed turbo-spin-echo sequence, optimized on a 0.5-T magnet with 15 mT/m gradients. Clinical applications of MRCP are evaluated, presenting data from both the literature and personal experience. The main indication for MRCP study is represented by the evaluation of common bile duct obstruction, with the aim of assessing the presence of the obstruction (accuracy 85-100 %) and, subsequently, its level (accuracy 91-100 %) and its cause. The utility of associating conventional MR images to MRCP in malignant strictures in order to characterize and stage the malignant lesions is also discussed. Finally, data are presented regarding the indications and utility of MR pancreatography in the evaluation of patients with chronic pancreatitis. (orig.) With 11 figs., 45 refs.

  6. Recent applications of nuclear track emulsion technique

    Energy Technology Data Exchange (ETDEWEB)

    Zarubin, P. I., E-mail: zarubin@lhe.jinr.ru [Joint Institute for Nuclear Research, Veksler and Baldin Laboratory of High Energy Physics (Russian Federation)

    2016-12-15

    A survey of recent results obtained using the nuclear track emulsion (NTE) technique in low energy applications is given. NTE irradiation with 60 MeV {sup 8}He nuclei provides identification of their decays at stopping, evaluation of the possibility of α range spectrometry, and observation of drift of thermalized {sup 8}He atoms. Correlations of α particles studied in {sup 12}C → 3α splitting induced by 14.1 MeV neutrons indicate the presence of a superposition of 0{sup +} and 2{sup +} states of the {sup 8}Be nucleus in the ground state of {sup 12}C. Angular correlations of fragments are studied in boron-enriched NTE, and the prospects of NTE application in radioactivity and nuclear fission research are discussed. It is proposed to use an automated microscope to search for collinear tripartition of heavy nuclei implanted in NTE. Surface irradiation of NTE by a {sup 252}Cf source is started. Planar events containing fragment pairs and long range α particles, as well as fragment triples, are studied. NTE samples are calibrated using Kr and Xe ions with an energy of 1.2 and 3 A MeV.

  7. Application of Electroporation Technique in Biofuel Processing

    Directory of Open Access Journals (Sweden)

    Yousuf Abu

    2017-01-01

    Full Text Available Biofuels production is mostly oriented with fermentation process, which requires fermentable sugar as nutrient for microbial growth. Lignocellulosic biomass (LCB represents the most attractive, low-cost feedstock for biofuel production, it is now arousing great interest. The cellulose that is embedded in the lignin matrix has an insoluble, highly-crystalline structure, so it is difficult to hydrolyze into fermentable sugar or cell protein. On the other hand, microbial lipid has been studying as substitute of plant oils or animal fat to produce biodiesel. It is still a great challenge to extract maximum lipid from microbial cells (yeast, fungi, algae investing minimum energy.Electroporation (EP of LCB results a significant increase in cell conductivity and permeability caused due to the application of an external electric field. EP is required to alter the size and structure of the biomass, to reduce the cellulose crystallinity, and increase their porosity as well as chemical composition, so that the hydrolysis of the carbohydrate fraction to monomeric sugars can be achieved rapidly and with greater yields. Furthermore, EP has a great potential to disrupt the microbial cell walls within few seconds to bring out the intracellular materials (lipid to the solution. Therefore, this study aims to describe the challenges and prospect of application of EP technique in biofuels processing.

  8. Application of TDS technique to developed reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Escobar, Freddy H.; Montealegre, Matilde [Petroleum Engineering Department, Universidad Surcolombiana, Av. Pastrana - Cra 1, Neiva (Huila-Colombia) (Colombia)

    2007-02-15

    Well test interpretation methods for a single well in infinite reservoirs may not be suitable for those wells when their pressure is affected by other wells operating in the same reservoir. This effect becomes more significant as both the flow rate and the test duration increase. It is observed in drawdown tests when the well experiences an additional pressure decline due to production from other wells and, also, when the well produces under pseudosteady state before shut-in it for a buildup test. When pressure data are interpreted as recorded, estimation of reservoir parameters may not be accurate. Slider1-3 introduced a technique for analyzing a pressure test that takes into account the effect of nearby active wells. Corrected or extrapolated pressures are obtained by applying the superposition principle to include the pressure decline contribution from the neighboring wells. Traditional semilog plots are then constructed and permeability and skin factor can be estimated, respectively, from the slope and intercept of their linear trend. A new technique, called TDS (Tiab's Direct Synthesis), was designed to analyze pressure and pressure derivative data without using type-curve matching. It uses characteristic features found on the derivative plot, so reservoir parameters are directly estimated. It depends upon how well the pressure derivative is calculated. If derivative is taken to the recorded pressure data the resulting curve will not be properly defined and the estimated parameters may be erroneous. Application of the TDS technique to wells in depleted reservoirs is presented here. The recorded pressure is extrapolated to include the contribution from other wells as suggested by Slider. Once the pressure derivative of the extrapolated data is taken, the TDS technique as discussed by Tiab [Tiab, D. 1993. Analysis of Pressure and Pressure Derivative without Type-Curve Matching: 1- Factor de dano and Wellbore Storage. J. Pet. Sci. Eng. 12 (1995), 171

  9. New approaches in intelligent control techniques, methodologies and applications

    CERN Document Server

    Kountchev, Roumen

    2016-01-01

    This volume introduces new approaches in intelligent control area from both the viewpoints of theory and application. It consists of eleven contributions by prominent authors from all over the world and an introductory chapter. This volume is strongly connected to another volume entitled "New Approaches in Intelligent Image Analysis" (Eds. Roumen Kountchev and Kazumi Nakamatsu). The chapters of this volume are self-contained and include summary, conclusion and future works. Some of the chapters introduce specific case studies of various intelligent control systems and others focus on intelligent theory based control techniques with applications. A remarkable specificity of this volume is that three chapters are dealing with intelligent control based on paraconsistent logics.

  10. The reliability of specific sacro-occipital technique diagnostic tests.

    Science.gov (United States)

    Leboeuf, C

    1991-01-01

    Four interexaminer and one intraexaminer agreement studies were performed on specific diagnostic tests commonly employed within sacro-occipital technique (SOT). Ten of the tests were evaluated in more than one interexaminer study. Of these, only one test (bilateral supine leg raise with cervical compaction) had at least fair reliability more than once. Six of these 10 tests obtained poor agreement in more than one study. One examiner out of two had a number of excellent and fair intraexaminer values, whereas the other examiner generally had poor results. There may have been some treatment effect as a comparison of the combined intraexaminer diagnosis for two observers after no treatment and after treatment showed that the repeatability diminished from Kappa of 0.36 in untreated cases (which were expected to have high agreement of before and after treatment findings) to a Kappa of 0.27 for those subjects having received treatment (which were expected to have low agreement of before and after treatment findings). It appears unlikely that SOT tests can be reproduced to a sufficiently high degree to constitute useful clinical procedures.

  11. Applications of Electromigration Techniques: Applications of Electromigration Techniques in Food Analysis

    Science.gov (United States)

    Wieczorek, Piotr; Ligor, Magdalena; Buszewski, Bogusław

    Electromigration techniques, including capillary electrophoresis (CE), are widely used for separation and identification of compounds present in food products. These techniques may also be considered as alternate and complementary with respect to commonly used analytical techniques, such as high-performance liquid chromatography (HPLC), or gas chromatography (GC). Applications of CE concern the determination of high-molecular compounds, like polyphenols, including flavonoids, pigments, vitamins, food additives (preservatives, antioxidants, sweeteners, artificial pigments) are presented. Also, the method developed for the determination of proteins and peptides composed of amino acids, which are basic components of food products, are studied. Other substances such as carbohydrates, nucleic acids, biogenic amines, natural toxins, and other contaminations including pesticides and antibiotics are discussed. The possibility of CE application in food control laboratories, where analysis of the composition of food and food products are conducted, is of great importance. CE technique may be used during the control of technological processes in the food industry and for the identification of numerous compounds present in food. Due to the numerous advantages of the CE technique it is successfully used in routine food analysis.

  12. Specification and compilation of real-time stream processing applications

    NARCIS (Netherlands)

    Geuns, Stephanus Joannes

    2015-01-01

    This thesis is concerned with the specification, compilation and corresponding temporal analysis of real-time stream processing applications that are executed on embedded multiprocessor systems. An example of such applications are software defined radio applications. These applications typically hav

  13. Designing Micro- and Nanoswimmers for Specific Applications.

    Science.gov (United States)

    Katuri, Jaideep; Ma, Xing; Stanton, Morgan M; Sánchez, Samuel

    2017-01-17

    Self-propelled colloids have emerged as a new class of active matter over the past decade. These are micrometer sized colloidal objects that transduce free energy from their surroundings and convert it to directed motion. The self-propelled colloids are in many ways, the synthetic analogues of biological self-propelled units such as algae or bacteria. Although they are propelled by very different mechanisms, biological swimmers are typically powered by flagellar motion and synthetic swimmers are driven by local chemical reactions, they share a number of common features with respect to swimming behavior. They exhibit run-and-tumble like behavior, are responsive to environmental stimuli, and can even chemically interact with nearby swimmers. An understanding of self-propelled colloids could help us in understanding the complex behaviors that emerge in populations of natural microswimmers. Self-propelled colloids also offer some advantages over natural microswimmers, since the surface properties, propulsion mechanisms, and particle geometry can all be easily modified to meet specific needs. From a more practical perspective, a number of applications, ranging from environmental remediation to targeted drug delivery, have been envisioned for these systems. These applications rely on the basic functionalities of self-propelled colloids: directional motion, sensing of the local environment, and the ability to respond to external signals. Owing to the vastly different nature of each of these applications, it becomes necessary to optimize the design choices in these colloids. There has been a significant effort to develop a range of synthetic self-propelled colloids to meet the specific conditions required for different processes. Tubular self-propelled colloids, for example, are ideal for decontamination processes, owing to their bubble propulsion mechanism, which enhances mixing in systems, but are incompatible with biological systems due to the toxic propulsion fuel and

  14. [Progress in transgenic fish techniques and application].

    Science.gov (United States)

    Ye, Xing; Tian, Yuan-Yuan; Gao, Feng-Ying

    2011-05-01

    Transgenic technique provides a new way for fish breeding. Stable lines of growth hormone gene transfer carps, salmon and tilapia, as well as fluorescence protein gene transfer zebra fish and white cloud mountain minnow have been produced. The fast growth characteristic of GH gene transgenic fish will be of great importance to promote aquaculture production and economic efficiency. This paper summarized the progress in transgenic fish research and ecological assessments. Microinjection is still the most common used method, but often resulted in multi-site and multi-copies integration. Co-injection of transposon or meganuclease will greatly improve the efficiency of gene transfer and integration. "All fish" gene or "auto gene" should be considered to produce transgenic fish in order to eliminate misgiving on food safety and to benefit expression of the transferred gene. Environmental risk is the biggest obstacle for transgenic fish to be commercially applied. Data indicates that transgenic fish have inferior fitness compared with the traditional domestic fish. However, be-cause of the genotype-by-environment effects, it is difficult to extrapolate simple phenotypes to the complex ecological interactions that occur in nature based on the ecological consequences of the transgenic fish determined in the laboratory. It is critical to establish highly naturalized environments for acquiring reliable data that can be used to evaluate the environ-mental risk. Efficacious physical and biological containment strategies remain to be crucial approaches to ensure the safe application of transgenic fish technology.

  15. Industrial applications of advanced control techniques

    Institute of Scientific and Technical Information of China (English)

    刘国平

    2003-01-01

    This paper discusses two industrial control applications using advanced control techniques. They are theoptimal-tuning nonlinear PID control of hydraulic systems and the neural predictive control of combustor acoustic ofgas turbines. For hydraulic control systems, an optimal PID controller with inverse of dead zone is introduced toovercome the dead zone and is designed to satisfy desired time-domain performance requirements. Using the adaptivemodel, an optimal-tuning PID control scheme is proposed to provide optimal PID parameters even in the case wherethe system dynamics is time variant. For combustor acoustic control of gas turbines, a neural predictive controlstrategy is presented, which consists of three parts: an output model, output predictor and feedback controller. Theoutput model of the combustor acoustic is established using neural networks to predict the output and overcome thetime delay of the system, which is often very large, compared with the sampling period. The output-feedback con-troller is introduced which uses the output of the predictor to suppress instability in the combustion process. The a-bove control strategies are implemented in the SIMULINK/dSPACE controller development environment. Theirperformance is evaluated on the industrial hydraulic test rig and the industrial combustor test rig.

  16. Study of multibeam techniques for bathymetry and seabottom backscatter applications

    Digital Repository Service at National Institute of Oceanography (India)

    Nair, R.R.; Chakraborty, B.

    In this paper, a brief discussion is carried out on the application of the different techniques of echosounding. A deteiled appraisal of the presently used multibeam technique is mentioned. Some of the important discoveries of seabed features around...

  17. Automatic generation of executable communication specifications from parallel applications

    Energy Technology Data Exchange (ETDEWEB)

    Pakin, Scott [Los Alamos National Laboratory; Wu, Xing [NCSU; Mueller, Frank [NCSU

    2011-01-19

    Portable parallel benchmarks are widely used and highly effective for (a) the evaluation, analysis and procurement of high-performance computing (HPC) systems and (b) quantifying the potential benefits of porting applications for new hardware platforms. Yet, past techniques to synthetically parameterized hand-coded HPC benchmarks prove insufficient for today's rapidly-evolving scientific codes particularly when subject to multi-scale science modeling or when utilizing domain-specific libraries. To address these problems, this work contributes novel methods to automatically generate highly portable and customizable communication benchmarks from HPC applications. We utilize ScalaTrace, a lossless, yet scalable, parallel application tracing framework to collect selected aspects of the run-time behavior of HPC applications, including communication operations and execution time, while abstracting away the details of the computation proper. We subsequently generate benchmarks with identical run-time behavior from the collected traces. A unique feature of our approach is that we generate benchmarks in CONCEPTUAL, a domain-specific language that enables the expression of sophisticated communication patterns using a rich and easily understandable grammar yet compiles to ordinary C + MPI. Experimental results demonstrate that the generated benchmarks are able to preserve the run-time behavior - including both the communication pattern and the execution time - of the original applications. Such automated benchmark generation is particularly valuable for proprietary, export-controlled, or classified application codes: when supplied to a third party. Our auto-generated benchmarks ensure performance fidelity but without the risks associated with releasing the original code. This ability to automatically generate performance-accurate benchmarks from parallel applications is novel and without any precedence, to our knowledge.

  18. Dancers' Application of the Alexander Technique

    Science.gov (United States)

    Fortin, Sylvie; Girard, Fernande

    2005-01-01

    This qualitative study describes the experience of professional contemporary dancers studying and applying the Alexander Technique to their dancing. This study was motivated by: 1. years of teaching both dance and somatics, 2. a strong desire to better understand how the Alexander Technique can be applied by dancers, and 3. a gap that the…

  19. Application of digital image processing techniques to astronomical imagery 1977

    Science.gov (United States)

    Lorre, J. J.; Lynn, D. J.

    1978-01-01

    Nine specific techniques of combination of techniques developed for applying digital image processing technology to existing astronomical imagery are described. Photoproducts are included to illustrate the results of each of these investigations.

  20. Applications of surface analytical techniques in Earth Sciences

    Science.gov (United States)

    Qian, Gujie; Li, Yubiao; Gerson, Andrea R.

    2015-03-01

    to show how each technique is applied and used to obtain specific information and to resolve real problems, which forms the central theme of this review. Although this review focuses on applications of these techniques to study mineralogical and geological samples, we also anticipate that researchers from other research areas such as Material and Environmental Sciences may benefit from this review.

  1. Nonlinear temporal pulse cleaning techniques and application

    Institute of Scientific and Technical Information of China (English)

    Yi; Xu; Jianzhou; Wang; Yansui; Huang; Yanyan; Li; Xiaomin; Lu; Yuxin; Leng

    2013-01-01

    Two different pulse cleaning techniques for ultra-high contrast laser systems are comparably analysed in this work.The first pulse cleaning technique is based on noncollinear femtosecond optical-parametric amplification(NOPA)and second-harmonic generation(SHG)processes.The other is based on cross-polarized wave(XPW)generation.With a double chirped pulse amplifier(double-CPA)scheme,although temporal contrast enhancement in a high-intensity femtosecond Ti:sapphire chirped pulse amplification(CPA)laser system can be achieved based on both of the techniques,the two different pulse cleaning techniques still have their own advantages and are suitable for different contrast enhancement requirements of different laser systems.

  2. Application of luminescence techniques in retrospective dosimetry

    DEFF Research Database (Denmark)

    Bøtter-Jensen, L.; Jungner, H.

    1999-01-01

    Luminescence signals measured from minerals within bricks or ceramic samples can provide information about the absorbed radiation dose. This feature has for several years been used in dating archaeological and geological samples and recently luminescence techniques have been intensively used far...... retrospective assessment of accident doses received by the population after a nuclear accident. The development of new luminescence techniques after the Chernobyl accident has considerably improved the sensitivity and precision in the evaluation of accident doses. This paper reviews the development work...

  3. A Disaster Document Classification Technique Using Domain Specific Ontologies

    Directory of Open Access Journals (Sweden)

    Qazi Mudassar Ilyas

    2015-12-01

    Full Text Available Manual data collection and entry is one of the bottlenecks in conventional disaster management information systems. Time is a critical factor in emergency situations and timely data collection and processing may help in saving several lives. An effective disaster management system needs to collect data from World Wide Web automatically. A prerequisite for data collection process is document classification mechanism to classify a particular document into different categories. Ontologies are formal bodies of knowledge used to capture machine understandable semantics of a domain of interest and have been used successfully to support document classification in various domains. This paper presents an ontology-based document classification technique for automatic data collection in a disaster management system. A general ontology of disasters is used that contains the description of several natural and man-made disasters. The proposed technique augments the conventional classification measures with the ontological knowledge to improve the precision of classification. A preliminary implementation of the proposed technique shows promising results with up to 10% overall improvement in precision when compared with conventional classification methods.

  4. Expert System Techniques and Applications in AEC-Design

    DEFF Research Database (Denmark)

    Andersen, Tom

    This part of a book presents expert system techniques applicable to building design and construction, and it reports and evaluates on systems developed in thar domain.......This part of a book presents expert system techniques applicable to building design and construction, and it reports and evaluates on systems developed in thar domain....

  5. 48 CFR 9904.417-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Techniques for application... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.417-50 Techniques for application. (a) The cost of money... capitalized, such as the method used for financial accounting and reporting, may be used, provided...

  6. 48 CFR 9904.401-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Techniques for application... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-50 Techniques for application. (a) The standard... in estimating costs in pricing a proposal and in accumulating and reporting costs on the...

  7. Moving objects management models, techniques and applications

    CERN Document Server

    Meng, Xiaofeng; Xu, Jiajie

    2014-01-01

    This book describes the topics of moving objects modeling and location tracking, indexing and querying, clustering, location uncertainty, traffic aware navigation and privacy issues as well as the application to intelligent transportation systems.

  8. Optical coherence tomography: Technique and applications

    DEFF Research Database (Denmark)

    Thomsen, Jakob Borup; Sander, Birgit; Mogensen, Mette;

    2009-01-01

    Optical coherence tomography (OCT) is a noninvasive optical imaging modality providing real-time video rate images in two and three dimensions of biological tissues with micrometer resolution. OCT fills the gap between ultrasound and confocal microscopy, since it has a higher resolution than ultr...... of retinal diseases. The potential of OCT in many other applications is currently being explored, such as in developmental biology, skin cancer diagnostics, vulnerable plaque detection in cardiology, esophageal diagnostics and a number of other applications within oncology....

  9. Applications of electrochemical techniques in mineral analysis.

    Science.gov (United States)

    Niu, Yusheng; Sun, Fengyue; Xu, Yuanhong; Cong, Zhichao; Wang, Erkang

    2014-09-01

    This review, covering reports published in recent decade from 2004 to 2013, shows how electrochemical (EC) techniques such as voltammetry, electrochemical impedance spectroscopy, potentiometry, coulometry, etc., have made significant contributions in the analysis of minerals such as clay, sulfide, oxide, and oxysalt. It was discussed based on the classifications of both the types of the used EC techniques and kinds of the analyzed minerals. Furthermore, minerals as electrode modification materials for EC analysis have also been summarized. Accordingly, research vacancies and future development trends in these areas are discussed.

  10. 3D-printed patient-specific applications in orthopedics

    Directory of Open Access Journals (Sweden)

    Wong KC

    2016-10-01

    Full Text Available Kwok Chuen Wong Department of Orthopedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong Abstract: With advances in both medical imaging and computer programming, two-dimensional axial images can be processed into other reformatted views (sagittal and coronal and three-dimensional (3D virtual models that represent a patients’ own anatomy. This processed digital information can be analyzed in detail by orthopedic surgeons to perform patient-specific orthopedic procedures. The use of 3D printing is rising and has become more prevalent in medical applications over the last decade as surgeons and researchers are increasingly utilizing the technology’s flexibility in manufacturing objects. 3D printing is a type of manufacturing process in which materials such as plastic or metal are deposited in layers to create a 3D object from a digital model. This additive manufacturing method has the advantage of fabricating objects with complex freeform geometry, which is impossible using traditional subtractive manufacturing methods. Specifically in surgical applications, the 3D printing techniques can not only generate models that give a better understanding of the complex anatomy and pathology of the patients and aid in education and surgical training, but can also produce patient-specific surgical guides or even custom implants that are tailor-made to the surgical requirements. As the clinical workflow of the 3D printing technology continues to evolve, orthopedic surgeons should embrace the latest knowledge of the technology and incorporate it into their clinical practice for patient-specific orthopedic applications. This paper is written to help orthopedic surgeons stay up-to-date on the emerging 3D technology, starting from the acquisition of clinical imaging to 3D printing for patient-specific applications in orthopedics. It 1 presents the necessary steps to prepare the medical images that are

  11. Big data for development : applications and techniques

    NARCIS (Netherlands)

    Ali, Anwaar; Qadir, Junaid; ur Rasool, Raihan; Sathiaseelan, Arjuna; Zwitter, Andrej; Crowcroft, Jon

    2016-01-01

    With the explosion of social media sites and proliferation of digital computing devices and Internet access, massive amounts of public data is being generated on a daily basis. Efficient techniques/algorithms to analyze this massive amount of data can provide near real-time information about emergin

  12. Big data for development : applications and techniques

    NARCIS (Netherlands)

    Ali, Anwaar; Qadir, Junaid; ur Rasool, Raihan; Sathiaseelan, Arjuna; Zwitter, Andrej; Crowcroft, Jon

    2016-01-01

    With the explosion of social media sites and proliferation of digital computing devices and Internet access, massive amounts of public data is being generated on a daily basis. Efficient techniques/algorithms to analyze this massive amount of data can provide near real-time information about

  13. Model checking timed automata : techniques and applications

    NARCIS (Netherlands)

    Hendriks, Martijn.

    2006-01-01

    Model checking is a technique to automatically analyse systems that have been modeled in a formal language. The timed automaton framework is such a formal language. It is suitable to model many realistic problems in which time plays a central role. Examples are distributed algorithms, protocols, emb

  14. Performance Comparisons of MIMO Techniques with Application to WCDMA Systems

    Directory of Open Access Journals (Sweden)

    Li Chuxiang

    2004-01-01

    Full Text Available Multiple-input multiple-output (MIMO communication techniques have received great attention and gained significant development in recent years. In this paper, we analyze and compare the performances of different MIMO techniques. In particular, we compare the performance of three MIMO methods, namely, BLAST, STBC, and linear precoding/decoding. We provide both an analytical performance analysis in terms of the average receiver and simulation results in terms of the BER. Moreover, the applications of MIMO techniques in WCDMA systems are also considered in this study. Specifically, a subspace tracking algorithm and a quantized feedback scheme are introduced into the system to simplify implementation of the beamforming scheme. It is seen that the BLAST scheme can achieve the best performance in the high data rate transmission scenario; the beamforming scheme has better performance than the STBC strategies in the diversity transmission scenario; and the beamforming scheme can be effectively realized in WCDMA systems employing the subspace tracking and the quantized feedback approach.

  15. Dynamic Binary Modification Tools, Techniques and Applications

    CERN Document Server

    Hazelwood, Kim

    2011-01-01

    Dynamic binary modification tools form a software layer between a running application and the underlying operating system, providing the powerful opportunity to inspect and potentially modify every user-level guest application instruction that executes. Toolkits built upon this technology have enabled computer architects to build powerful simulators and emulators for design-space exploration, compiler writers to analyze and debug the code generated by their compilers, software developers to fully explore the features, bottlenecks, and performance of their software, and even end-users to extend

  16. Application of luminescence techniques in retrospective dosimetry

    DEFF Research Database (Denmark)

    Bøtter-Jensen, L.; Jungner, H.

    1999-01-01

    Luminescence signals measured from minerals within bricks or ceramic samples can provide information about the absorbed radiation dose. This feature has for several years been used in dating archaeological and geological samples and recently luminescence techniques have been intensively used far...... retrospective assessment of accident doses received by the population after a nuclear accident. The development of new luminescence techniques after the Chernobyl accident has considerably improved the sensitivity and precision in the evaluation of accident doses. This paper reviews the development work......, especially on optically stimulated luminescence methods for retrospective assessment of accident doses carried out at Riso National Laboratory in collaboration with the University of Helsinki as part bf a joint European Union research project. We demonstrate that doses lower than 100 mGy can be measured from...

  17. Application of PCR techniques in toxicology

    Directory of Open Access Journals (Sweden)

    Maja Kazubek

    2010-10-01

    Full Text Available Molecular biology techniques have become widely used in toxicology, leading to the creation of a new science – molecular toxicology. The goal of molecular toxicology is to detect and study the changes induced by xenobiotics at the molecular level. The research scope of molecular toxicology includes examination of mutations in genomic DNA, differences in mRNA expression and study of genotype indicating individual sensitivity.The processes of activation and detoxification of xenobiotics, drugs and environmental carcinogens involve several enzymes (xenobiotic-metabolizing enzymes – XMEs. Most of the chemicals entering our bodies, regardless of whether they have medical, pathogenic or carcinogenic properties, require metabolic activation by phase I enzymes (cytochrome P-450. In the next process the phase I products are usually detoxified by phase II enzymes, mainly by epoxide hydrolase, glutathione transferase, N-acetyltransferase or sulfotransferase. PCR techniques allow precise study of the effects of xenobiotics on cells and tissues by examining the level of activation of genes coding for phase I and II enzymes, or by testing the activity of other elements of the transcriptome. Studies of sensitivity of individual cells or tissues based on examination of mutation or gene polymorphism presence are also relevant.This paper presents the possibility of using various PCR techniques in toxicology and especially in the study of genetically determined sensitivity to xenobiotics. It also covers the possibilities of applying qPCR and qRT-PCR methods in the search for exposure biomarkers with particular emphasis on individual cytochrome P450 isoforms. Furthermore, it provides information about the possibility of implementing the differential display technique in the identification of new genes activated by toxic agents.

  18. Application of Tuina Techniques to Spinal Diseases

    Institute of Scientific and Technical Information of China (English)

    FANG Min; SHEN Guo-quan; YAN Jun-tao; HAN Chou-ping

    2003-01-01

    @@ It's one of the earliest medical techniques to relieve pain, restore health and enjoy comfort with manipulations. Knowledge on spinal neck pain, shoulder pain, low back pain and leg pain can be traced back to the early stage of human evolution and upright position of two legs. Therefore the history of treating spinal diseases with Tuina or manipulations probably keeps the same pace with civilization.

  19. Terahertz spectroscopy and imaging – Modern techniques and applications

    DEFF Research Database (Denmark)

    Jepsen, Peter Uhd; Cooke, David; Koch, Martin

    2011-01-01

    Over the past three decades a new spectroscopic technique with unique possibilities has emerged. Based on coherent and time-resolved detection of the electric field of ultrashort radiation bursts in the far-infrared, this technique has become known as terahertz time-domain spectroscopy (THz-TDS)....... of research, where THz spectroscopic techniques have proven to be useful research tools, and the potential for industrial applications of THz spectroscopic and imaging techniques are discussed....

  20. Techniques for Finding Vulnerabilities in Web Applications

    Directory of Open Access Journals (Sweden)

    Mihai Sandulescu

    2014-03-01

    Full Text Available The current trend is to move everything on the Internet. Because a lot of companies store sensitive user information, security has become mandatory. Usually, software developers don’t follow some basic practices in order to secure their applications. This paper will present in the second chapter, the white-box, black-box and gray-box methods which can be used in order to test applications for possible vulnerabilities. It focuses on fuzz testing, which is a black-box testing method, presented in the third chapter. The fourth chapter presents the stages of a fuzzing test and in the final chapter, we show a basic practical example on how to use the Burp Suite[8] fuzzer to find a vulnerability.

  1. Neutron Scattering in Biology Techniques and Applications

    CERN Document Server

    Fitter, Jörg; Katsaras, John

    2006-01-01

    The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.

  2. RPC application in muography and specific developments

    CERN Document Server

    Menedeu, Eve Le

    2016-01-01

    Muography is an imaging technique for large and dense structures as volcanoes or nuclear reactors using atmospheric muons. We applied this technique to the observation of the Puy de D\\^ome, a volcano 2 km wide close to Clermont-Ferrand, France. The detection is performed with a 1m$\\times$1m$\\times$1.80m telescope made of 4 layers of single gap glass-RPCs operated in avalanche mode. The 1 cm$^2$ pad readout uses the Hardroc2 ASICs. The three data taking campaigns over the last three years showed that a RPC detector can be operated in-situ with good performances. Further developments to decrease the gas and power consumption and to improve the position and timing resolution of the detector are ongoing.

  3. Hardware Compilation of Application-Specific Memory-Access Interconnect

    DEFF Research Database (Denmark)

    Venkataramani, Girish; Bjerregaard, Tobias; Chelcea, Tiberiu;

    2006-01-01

    . SOMA synthesizes a memory access network (MAN) architecture that facilitates dynamic scheduling and ordering of memory accesses. The paper describes a basic MAN construction technique that illustrates how dynamic ordering helps in efficiently maintaining memory consistency and how dynamic scheduling......A major obstacle to successful high-level synthesis (HLS) of large-scale application-specified integrated circuit systems is the presence of memory accesses to a shared-memory subsystem. The latency to access memory is often not statically predictable, which creates problems for scheduling...... operations dependent on memory reads. More fundamental is that dependences between accesses may not be statically provable (e.g., if the specification language permits pointers), which introduces memory-consistency problems. Addressing these issues with static scheduling results in overly conservative...

  4. Application of optical spectroscopic techniques for disease diagnosis

    Science.gov (United States)

    Saha, Anushree

    Optical spectroscopy, a truly non-invasive tool for remote diagnostics, is capable of providing valuable information on the structure and function of molecules. However, most spectroscopic techniques suffer from drawbacks, which limit their application. As a part of my dissertation work, I have developed theoretical and experimental methods to address the above mentioned issues. I have successfully applied these methods for monitoring the physical, chemical and biochemical parameters of biomolecules involved in some specific life threatening diseases like lead poisoning and age-related macular degeneration (AMD). I presented optical studies of melanosomes, which are one of the vital organelles in the human eye, also known to be responsible for a disease called age-related macular degeneration (AMD), a condition of advanced degeneration which causes progressive blindness. I used Raman spectroscopy, to first chemically identify the composition of melanosome, and then monitor the changes in its functional and chemical behavior due to long term exposure to visible light. The above study, apart from explaining the role of melanosomes in AMD, also sets the threshold power for lasers used in surgeries and other clinical applications. In the second part of my dissertation, a battery of spectroscopic techniques was successfully applied to explore the different binding sites of lead ions with the most abundant carrier protein molecule in our circulatory system, human serum albumin. I applied optical spectroscopic tools for ultrasensitive detection of heavy metal ions in solution which can also be used for lead detection at a very early stage of lead poisoning. Apart from this, I used Raman microspectroscopy to study the chemical alteration occurring inside a prostate cancer cell as a result of a treatment with a low concentrated aqueous extract of a prospective drug, Nerium Oleander. The experimental methods used in this study has tremendous potential for clinical

  5. Applications of observational techniques in pavement engineering

    CSIR Research Space (South Africa)

    Steyn, WJVDM

    2007-05-01

    Full Text Available includes engineers, site agents, contractors, managers and anybody else that has a specific concern with roads and their functioning) has a daily requirement to record events on roads. These include the whole spectrum of the life of a road, starting... to the travelling public include the following: • Visual evaluation of pavement condition as required for Pavement Management Systems (PMS) and rehabilitation evaluations; • Forensic investigations of failures on pavements; • Construction / as-built records...

  6. The six-port technique with microwave and wireless applications

    CERN Document Server

    Ghannouchi, Fadhel M

    2009-01-01

    One of the main issues in microwave and wireless system design is to ensure high performance with low cost techniques. The six-port technique helps allow for this in critical network design areas. This practical resource offers you a thorough overview the six-port technique, from basic principles of RF measurement based techniques and multiport design, to coverage of key applications, such as vector network analyzers, software defined radio, and radar. The first book dedicated to six-port applications and principles, this volume serves as a current, one-stop guide offering you cost-effective s

  7. ProThes: Thesaurus-based Meta-Search Engine for a Specific Application Domain

    OpenAIRE

    Braslavski, P.; Alshanski, G.; Shishkin, A.; П.И. Браславский

    2004-01-01

    In this poster we introduce ProThes, a pilot meta-search engine (MSE) for a specific application domain. ProThes combines three approaches: meta-search, graphical user interface (GUI) for query specification, and thesaurus-based query techniques. ProThes attempts to employ domain-specific knowledge, which is represented by both a conceptual thesaurus and results ranking heuristics. Since the knowledge representation is separated from the MSE core, adjusting the system to a specific domain is ...

  8. Real analysis modern techniques and their applications

    CERN Document Server

    Folland, Gerald B

    1999-01-01

    An in-depth look at real analysis and its applications-now expanded and revised.This new edition of the widely used analysis book continues to cover real analysis in greater detail and at a more advanced level than most books on the subject. Encompassing several subjects that underlie much of modern analysis, the book focuses on measure and integration theory, point set topology, and the basics of functional analysis. It illustrates the use of the general theories and introduces readers to other branches of analysis such as Fourier analysis, distribution theory, and probability theory.This edi

  9. Laser induced fluorescence technique for environmental applications

    Science.gov (United States)

    Utkin, Andrei B.; Felizardo, Rui; Gameiro, Carla; Matos, Ana R.; Cartaxana, Paulo

    2014-08-01

    We discuss the development of laser induced fluorescence sensors and their application in the evaluation of water pollution and physiological status of higher plants and algae. The sensors were built on the basis of reliable and robust solid-state Nd:YAG lasers. They demonstrated good efficiency in: i) detecting and characterizing oil spills and dissolved organic matter; ii) evaluating the impact of stress on higher plants (cork oak, maritime pine, and genetically modified Arabidopsis); iii) tracking biomass changes in intertidal microphytobenthos; and iv) mapping macroalgal communities in the Tagus Estuary.

  10. Defectoscopic and Clinical Applications of Infrared Technique

    Science.gov (United States)

    Kopal, I.; Koštial, P.; Špička, I.; Pleva, L.; Jančíková, Z.

    2017-02-01

    The article deals with possible visualization of inhomogeneities in inorganic materials, such as laminates, as well as organic materials, such as bones. This work also provides a study of the visualization of internal fixation (nail), introduced in a bone by the IR technique. In the theoretical part, we present thermal wave propagation and a theoretical approach to the possibility of visualization of the boundary between two different materials with different thermal conductivity. Further on, the experimental method is tested with success on discovering artificial defects in glass laminates. In the second part of the article, a successful method of the visualization of the internal fixator position in a bone under IR excitation is presented. Methods of processing the data measured with the use of an infrared camera are presented in detail.

  11. Surface modification: advantages, techniques, and applications

    Energy Technology Data Exchange (ETDEWEB)

    Natesan, K.

    2000-03-01

    Adequate performance of materials at elevated temperatures is a potential problem in many systems within the chemical, petroleum, process, and power-generating industries. Degradation of materials occurs because of interaction between the structural material and the exposure environment. These interactions are generally undesired chemical reactions that can lead to accelerated wastage and alter the functional requirements and/or structural integrity of the materials. Therefore, material selection for high-temperature applications must be based not only on a material strength properties but also on resistance to the complex environments prevalent in the anticipated exposure environment. As plants become larger, the satisfactory performance and reliability of components play a greater role in plant availability and economics. However, system designers are becoming increasingly concerned with finding the least expensive material that will satisfactorily perform the design function for the desired service life. This present paper addresses the benefits of surface modification and identified several criteria for selection and application of modified surfaces in the power sector. A brief review is presented on potential methods for modification of surfaces, with the emphasis on coatings. In the final section of the paper, several examples address the requirements of different energy systems and surface modification avenues that have been applied to resolve the issues.

  12. Application of image fusion techniques in DSA

    Science.gov (United States)

    Ye, Feng; Wu, Jian; Cui, Zhiming; Xu, Jing

    2007-12-01

    Digital subtraction angiography (DSA) is an important technology in both medical diagnoses and interposal therapy, which can eliminate the interferential background and give prominence to blood vessels by computer processing. After contrast material is injected into an artery or vein, a physician produces fluoroscopic images. Using these digitized images, a computer subtracts the image made with contrast material from a series of post injection images made without background information. By analyzing the characteristics of DSA medical images, this paper provides a solution of image fusion which is in allusion to the application of DSA subtraction. We fuse the images of angiogram and subtraction, in order to obtain the new image which has more data information. The image that fused by wavelet transform can display the blood vessels and background information clearly, and medical experts gave high score on the effect of it.

  13. Application of goal programming technique in government statutory ...

    African Journals Online (AJOL)

    Application of goal programming technique in government statutory budget in Anambra State. ... Open Access DOWNLOAD FULL TEXT ... data obtained from the 15 communities of Orumba South Local Government Area of Anambra State.

  14. Model Driven Testing of Web Applications Using Domain Specific Language

    OpenAIRE

    Viet-Cuong Nguyen

    2015-01-01

    As more and more systems move to the cloud, the importance of web applications has increased recently. Web applications need more strict requirements in order to sup-port higher availability. The techniques in quality assurance of these applications hence become essential, the role of testing for web application becomes more significant. Model-driven testing is a promising paradigm for the automation of software testing. In the web domain, the challenge however remains in the creation of mode...

  15. Application of ellipsometry techniques to biological materials

    Energy Technology Data Exchange (ETDEWEB)

    Arwin, Hans, E-mail: han@ifm.liu.s

    2011-02-28

    Ellipsometry is well-suited for bioadsorption studies and numerous reports, mainly using null ellipsometry, are found on this subject whereas investigations addressing structural properties of thin biolayers are few. Here two examples based on the use of spectroscopic ellipsometry (SE) on the latter are briefly discussed. In the first example, time evolution of thickness, spectral refractive index and surface mass density of a fibrinogen matrix forming on a silicon substrate are investigated with SE and a structural model of the protein matrix is discussed. In the second example a model dielectric function concept for protein monolayers is presented. The model allows parameterization of the optical properties which facilitates monitoring of temperature induced degradation of a protein layer. More recently, photonic structures in beetles have been studied with SE. It is shown here that full Mueller-matrix SE can resolve very complex nanostructures in scarab beetles, more specifically chiral structures causing reflected light to become circularly polarized.

  16. CLP application to nanomaterials: a specific aspect

    Directory of Open Access Journals (Sweden)

    Maria Alessandrelli

    2011-01-01

    Full Text Available This paper aims at describing some relevant aspects related to the classification, labelling and packaging of nanomaterials. Concerns have been raised about potential adverse effects to humans or the environment as result of impacts of nanomaterials. The new Regulation (EC no. 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP does not contain any specific definition or provision related to nanomaterials nevertheless they are covered by the definition of substance set in the Regulation. It is recognized that different particle sizes or forms of the same substance can have different classification. Thus, if substances are placed on the market both at nanoscale and as bulk, a separate classification and labelling may be required if the available data on the intrinsic properties indicate a difference in hazard class between the two forms. CLP Regulation requires the manufacturer or importer to ensure that the information used to classify relates to the forms or physical states in which the substance is placed on the market and in which it can reasonably be expected to be used. Moreover, CLP demands testing relating to physical hazards to be performed if such information is missing or not adequate to conclude on classification. Further developments of the CLP guidance documents and implementation tools are needed in order to cover nanomaterials more specifically.

  17. 10 CFR 40.31 - Application for specific licenses.

    Science.gov (United States)

    2010-01-01

    ... Application for specific licenses. (a) A person may file an application for specific license on NRC Form 313... equipment. (vi) Assessment of releases. A brief description of the methods and equipment to assess releases... description of the means of restoring the facility to a safe condition after an accident. (xii)...

  18. [Application of molecular biological techniques in Taenia identification].

    Science.gov (United States)

    Li, Yan; Liu, Hang; Yang, Yi-Mei

    2011-10-01

    The traditional identification of Taenia spp. based on morphological features of adult and cysticercus has difficulties in identifying the morphologically similar species. The recent development of molecular techniques provides more scientific ways for distinguishing Taenia species. This paper summarizes the application of molecular biological techniques in the identification of Taenia, such as analysis of DNA sequence, PCR-RFLP and LAMP.

  19. 48 CFR 9905.501-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Techniques for application... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS FOR EDUCATIONAL INSTITUTIONS 9905.501-50 Techniques for... practices used in estimating costs in pricing a proposal and in accumulating and reporting costs on...

  20. Sterilization techniques for biodegradable scaffolds in tissue engineering applications

    Science.gov (United States)

    Dai, Zheng; Ronholm, Jennifer; Tian, Yiping; Sethi, Benu; Cao, Xudong

    2016-01-01

    Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on different sterilization techniques including heat, chemical, irradiation, and other novel sterilization techniques for various biodegradable scaffolds. Comparisons of these techniques, including their sterilization mechanisms, post-sterilization effects, and sterilization efficiencies, are discussed. PMID:27247758

  1. Different Techniques of MRU: Pitfalls & Clinical Applications

    Directory of Open Access Journals (Sweden)

    H. Nayyeri

    2005-08-01

    Full Text Available Introduction & Background: Magnetic resonance urography (MRU refers to MR imaging of the urinary col-lecting systems and it provides information roughly analogous to conventional intravenous urography. There are two basic MRU imaging strategies, (1 Static MRU uses T2W scans and rely on the presence of fluid in the pelvicaliceal systems and the ureters; (2 Excretory MRU is performed after administration of IV Gd using a 3D gradient echo sequence. Static MRU is best used for dilated collecting systems and can be employed regardless of renal function. Excretory MRU is usually preferred over static techniques for the demonstration of non-distended ureters; however, it is contraindicated in severely impaired renal function. As MR urograms are often displayed as maximum intensity projections, a low signal intensity ureteral stone surrounded by high signal intensity urine may be obscured on maximum intensity projection images. A prob-lem in static MR urography is the superimposition of fluid-filled structures (i.e. bowel loops, gall bladder and bile ducts, CSF, or any intraabdominal fluid collection on reconstructed images which may create false posi-tive findings or obscure true abnormalities. Non-distended ureters may escape detection on static MR uro-grams, resulting in the incorrect diagnosis of complete ureteral obstruction. Parapelvic cysts may simulate hy-dronephrosis while calyceal diverticulae may simulate simple renal cysts on static MRU. Excretory MR urography is performed in all such cases; however, Gd may create different problems when it becomes too concentrated within the collecting system. Sufficiently concentrated Gd shortens T2 relaxation times to the point that signal loss from T2 relaxation exceeds the T1 shortening effects of the contrast agent. This may result in poor visualization of all or a portion of collecting system on T1W images. Concentrated Gd in the renal collecting system also causes signal loss on T2W images

  2. Processing Techniques and Applications of Silk Hydrogels in Bioengineering

    Directory of Open Access Journals (Sweden)

    Michael Floren

    2016-09-01

    Full Text Available Hydrogels are an attractive class of tunable material platforms that, combined with their structural and functional likeness to biological environments, have a diversity of applications in bioengineering. Several polymers, natural and synthetic, can be used, the material selection being based on the required functional characteristics of the prepared hydrogels. Silk fibroin (SF is an attractive natural polymer for its excellent processability, biocompatibility, controlled degradation, mechanical properties and tunable formats and a good candidate for the fabrication of hydrogels. Tremendous effort has been made to control the structural and functional characteristic of silk hydrogels, integrating novel biological features with advanced processing techniques, to develop the next generation of functional SF hydrogels. Here, we review the several processing methods developed to prepare advanced SF hydrogel formats, emphasizing a bottom-up approach beginning with critical structural characteristics of silk proteins and their behavior under specific gelation environments. Additionally, the preparation of SF hydrogel blends and other advanced formats will also be discussed. We conclude with a brief description of the attractive utility of SF hydrogels in relevant bioengineering applications.

  3. Processing Techniques and Applications of Silk Hydrogels in Bioengineering

    Science.gov (United States)

    Floren, Michael; Migliaresi, Claudio; Motta, Antonella

    2016-01-01

    Hydrogels are an attractive class of tunable material platforms that, combined with their structural and functional likeness to biological environments, have a diversity of applications in bioengineering. Several polymers, natural and synthetic, can be used, the material selection being based on the required functional characteristics of the prepared hydrogels. Silk fibroin (SF) is an attractive natural polymer for its excellent processability, biocompatibility, controlled degradation, mechanical properties and tunable formats and a good candidate for the fabrication of hydrogels. Tremendous effort has been made to control the structural and functional characteristic of silk hydrogels, integrating novel biological features with advanced processing techniques, to develop the next generation of functional SF hydrogels. Here, we review the several processing methods developed to prepare advanced SF hydrogel formats, emphasizing a bottom-up approach beginning with critical structural characteristics of silk proteins and their behavior under specific gelation environments. Additionally, the preparation of SF hydrogel blends and other advanced formats will also be discussed. We conclude with a brief description of the attractive utility of SF hydrogels in relevant bioengineering applications. PMID:27649251

  4. 48 CFR 9904.416-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... actuarial present value of benefits applicable to employees already retired shall be amortized over a period... incurred, the amount of the loss to be recognized currently shall be the present value of the future... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.416-50 Techniques for application. (a) Measurement...

  5. Intelligent techniques in engineering management theory and applications

    CERN Document Server

    Onar, Sezi

    2015-01-01

    This book presents recently developed intelligent techniques with applications and theory in the area of engineering management. The involved applications of intelligent techniques such as neural networks, fuzzy sets, Tabu search, genetic algorithms, etc. will be useful for engineering managers, postgraduate students, researchers, and lecturers. The book has been written considering the contents of a classical engineering management book but intelligent techniques are used for handling the engineering management problem areas. This comprehensive characteristics of the book makes it an excellent reference for the solution of complex problems of engineering management. The authors of the chapters are well-known researchers with their previous works in the area of engineering management.

  6. Industrial heating principles, techniques, materials, applications, and design

    CERN Document Server

    Deshmukh, Yeshvant V

    2005-01-01

    Industry relies on heating for a wide variety of processes involving a broad range of materials. Each process and material requires heating methods suitable to its properties and the desired outcome. Despite this, the literature lacks a general reference on design techniques for heating, especially for small- and medium-sized applications. Industrial Heating: Principles, Techniques, Materials, Applications, and Design fills this gap, presenting design information for both traditional and modern heating processes and auxiliary techniques.The author leverages more than 40 years of experience int

  7. Review on Micro- and Nanolithography Techniques and Their Applications

    Directory of Open Access Journals (Sweden)

    Werayut Srituravanich

    2012-01-01

    Full Text Available This article reviews major micro- and nanolithography techniques and their applications from commercial micro devices to emerging applications in nanoscale science and engineering. Micro- and nanolithography has been the key technology in manufacturing of integrated circuits and microchips in the semiconductor industry. Such a technology is also sparking a magnificent transformation of nanotechnology. The lithography techniques including photolithography, electron beam lithography, focused ion beam lithography, soft lithography, nanoimprint lithography and scanning probe lithography are discussed. Furthermore, their applications are reviewed and summarized into four major areas: electronics and microsystems, medical and biotech, optics and photonics, and environment and energy harvesting.

  8. Millimeter-wave/THz FMCW radar techniques for sensing applications

    Science.gov (United States)

    Mirando, D. Amal; Higgins, Michael D.; Wang, Fenggui; Petkie, Douglas T.

    2016-10-01

    Millimeter-wave and terahertz continuous-wave radar systems have been used to measure physiological signatures for biometric applications and for a variety of non-destructive evaluation applications, such as the detection of defects in materials. Sensing strategies for the simplest homodyne systems, such as a Michelson Interferometer, can be enhanced by using Frequency Modulated Continuous Wave (FMCW) techniques. This allows multiple objects or surfaces to be range resolved while monitoring the phase of the signal in a particular range bin. We will discuss the latest developments in several studies aimed at demonstrating how FMCW techniques can enhance mmW/THz sensing applications.

  9. Application of Freeman Chain Codes: An Alternative Recognition Technique for Malaysian Car Plates

    CERN Document Server

    Jusoh, Nor Amizam

    2011-01-01

    Various applications of car plate recognition systems have been developed using various kinds of methods and techniques by researchers all over the world. The applications developed were only suitable for specific country due to its standard specification endorsed by the transport department of particular countries. The Road Transport Department of Malaysia also has endorsed a specification for car plates that includes the font and size of characters that must be followed by car owners. However, there are cases where this specification is not followed. Several applications have been developed in Malaysia to overcome this problem. However, there is still problem in achieving 100% recognition accuracy. This paper is mainly focused on conducting an experiment using chain codes technique to perform recognition for different types of fonts used in Malaysian car plates.

  10. MO-E-12A-01: Quantitative Imaging: Techniques, Applications, and Challenges

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, E; Jeraj, R [University of Wisconsin, Madison, WI (United States); McNitt-Gray, M [UCLA School of Medicine, Los Angeles, CA (United States); Cao, Y [University of Michigan, Ann Arbor, MI (United States)

    2014-06-15

    The first symposium in the Quantitative Imaging Track focused on the introduction of quantitative imaging (QI) by illustrating the potential of QI in diagnostic and therapeutic applications in research and patient care, highlighting key challenges in implementation of such QI applications, and reviewing QI efforts of selected national and international agencies and organizations, including the FDA, NCI, NIST, and RSNA. This second QI symposium will focus more specifically on the techniques, applications, and challenges of QI. The first talk of the session will focus on modalityagnostic challenges of QI, beginning with challenges of the development and implementation of QI applications in single-center, single-vendor settings and progressing to the challenges encountered in the most general setting of multi-center, multi-vendor settings. The subsequent three talks will focus on specific QI challenges and opportunities in the modalityspecific settings of CT, PET/CT, and MR. Each talk will provide information on modality-specific QI techniques, applications, and challenges, including current efforts focused on solutions to such challenges. Learning Objectives: Understand key general challenges of QI application development and implementation, regardless of modality. Understand selected QI techniques and applications in CT, PET/CT, and MR. Understand challenges, and potential solutions for such challenges, for the applications presented for each modality.

  11. Review of Matrix Decomposition Techniques for Signal Processing Applications

    Directory of Open Access Journals (Sweden)

    Monika Agarwal,

    2014-01-01

    Full Text Available Decomposition of matrix is a vital part of many scientific and engineering applications. It is a technique that breaks down a square numeric matrix into two different square matrices and is a basis for efficiently solving a system of equations, which in turn is the basis for inverting a matrix. An inverting matrix is a part of many important algorithms. Matrix factorizations have wide applications in numerical linear algebra, in solving linear systems, computing inertia, and rank estimation is an important consideration. This paper presents review of all the matrix decomposition techniques used in signal processing applications on the basis of their computational complexity, advantages and disadvantages. Various Decomposition techniques such as LU Decomposition, QR decomposition , Cholesky decomposition are discussed here. Keywords –

  12. Videogrammetric Model Deformation Measurement Technique for Wind Tunnel Applications

    Science.gov (United States)

    Barrows, Danny A.

    2006-01-01

    Videogrammetric measurement technique developments at NASA Langley were driven largely by the need to quantify model deformation at the National Transonic Facility (NTF). This paper summarizes recent wind tunnel applications and issues at the NTF and other NASA Langley facilities including the Transonic Dynamics Tunnel, 31-Inch Mach 10 Tunnel, 8-Ft high Temperature Tunnel, and the 20-Ft Vertical Spin Tunnel. In addition, several adaptations of wind tunnel techniques to non-wind tunnel applications are summarized. These applications include wing deformation measurements on vehicles in flight, determining aerodynamic loads based on optical elastic deformation measurements, measurements on ultra-lightweight and inflatable space structures, and the use of an object-to-image plane scaling technique to support NASA s Space Exploration program.

  13. The innovative application of surface geophysical techniques for remedial investigations

    Energy Technology Data Exchange (ETDEWEB)

    Saunders, W.R. [OYO Geospace, Fort Myers, FL (United States); Smith, S. [ICF Kaiser Engineers, Boston, MA (United States); Gilmore, P. [Fishbeck, Thomson, Carr and Huber, Aida, MI (United States); Cox, S. [Blasland, Bouck, and Lee, Edison, NJ (United States)

    1993-03-01

    When researchers are investigating potential subsurface contamination at hazardous waste landfills, the surface geophysical techniques they may use are often limited. Many geophysical surveys are concerned with areas next to and not directly within the landfill units. The highly variable properties of the materials within the landfill may result in geophysical data that are either difficult or impossible to interpret. Therefore, contamination at these sites may not be detected until substantial lateral migration away from the unit has occurred. In addition, because of the poor resolution of some techniques, the landfill as a whole must be considered as a source, where discrete disposal areas within landfill units may be the actual point sources of contaminants. In theory, if specific sources within the landfill are identified and isolated, then reduced time, effort, and expenditures will be required for remediation activities. In the summer of 1989, the Idaho National Engineering Laboratory (INEL) investigated a small potentially hazardous waste landfill to determine if contaminant hot spots could be identified within the landfill and to determine if significant vertical and lateral migration of contaminants was occurring away from these locations. Based on the present hydrogeologic conditions, researchers anticipated that subsurface flow would be primarily vertical, with the zone of saturation at a depth greater than 150 meters. This necessitated that the survey be performed, for the most part, directly on the capped portion of the landfill. Focused geophysical surveys conducted off the landfill would not have provided useful information concerning conditions directly beneath the landfill. This paper discusses the planning, application, and analysis of four combined sensing methods: two methods of electromagnetic induction [low induction (Em) and time domain (TEM)], ground penetrating radar (GPR), and soil gas.

  14. Specification Patent Management for Web Application Platform Ecosystem

    Science.gov (United States)

    Fukami, Yoshiaki; Isshiki, Masao; Takeda, Hideaki; Ohmukai, Ikki; Kokuryo, Jiro

    Diversified usage of web applications has encouraged disintegration of web platform into management of identification and applications. Users make use of various kinds of data linked to their identity with multiple applications on certain social web platforms such as Facebook or MySpace. There has emerged competition among web application platforms. Platformers can design relationship with developers by controlling patent of their own specification and adopt open technologies developed external organizations. Platformers choose a way to open according to feature of the specification and their position. Patent management of specification come to be a key success factor to build competitive web application platforms. Each way to attract external developers such as standardization, open source has not discussed and analyzed all together.

  15. Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields

    CERN Document Server

    Morris, Michael D

    2010-01-01

    The book presents the latest technological advances in Raman spectroscopy that are presently redrawing the landscape of many fields of biomedical and pharmaceutical R&D. Numerous examples are given to illustrate the application of the new methods and compared with established and related techniques. The book is suitable for both new researchers and practitioners in this area as well as for those familiar with the Raman technique but seeking to keep abreast of the latest dramatic advances in this field.

  16. Review and classification of variability analysis techniques with clinical applications.

    Science.gov (United States)

    Bravi, Andrea; Longtin, André; Seely, Andrew J E

    2011-10-10

    Analysis of patterns of variation of time-series, termed variability analysis, represents a rapidly evolving discipline with increasing applications in different fields of science. In medicine and in particular critical care, efforts have focussed on evaluating the clinical utility of variability. However, the growth and complexity of techniques applicable to this field have made interpretation and understanding of variability more challenging. Our objective is to provide an updated review of variability analysis techniques suitable for clinical applications. We review more than 70 variability techniques, providing for each technique a brief description of the underlying theory and assumptions, together with a summary of clinical applications. We propose a revised classification for the domains of variability techniques, which include statistical, geometric, energetic, informational, and invariant. We discuss the process of calculation, often necessitating a mathematical transform of the time-series. Our aims are to summarize a broad literature, promote a shared vocabulary that would improve the exchange of ideas, and the analyses of the results between different studies. We conclude with challenges for the evolving science of variability analysis.

  17. 9th International Conference on Optimization : Techniques and Applications

    CERN Document Server

    Wang, Song; Wu, Soon-Yi

    2015-01-01

    This book presents the latest research findings and state-of-the-art solutions on optimization techniques and provides new research direction and developments. Both the theoretical and practical aspects of the book will be much beneficial to experts and students in optimization and operation research community. It selects high quality papers from The International Conference on Optimization: Techniques and Applications (ICOTA2013). The conference is an official conference series of POP (The Pacific Optimization Research Activity Group; there are over 500 active members). These state-of-the-art works in this book authored by recognized experts will make contributions to the development of optimization with its applications.

  18. Application of optimisation techniques in groundwater quantity and quality management

    Indian Academy of Sciences (India)

    Amlan Das; Bithin Datta

    2001-08-01

    This paper presents the state-of-the-art on application of optimisation techniques in groundwater quality and quantity management. In order to solve optimisation-based groundwater management models, researchers have used various mathematical programming techniques such as linear programming (LP), nonlinear programming (NLP), mixed-integer programming (MIP), optimal control theory-based mathematical programming, differential dynamic programming (DDP), stochastic programming (SP), combinatorial optimisation (CO), and multiple objective programming for multipurpose management. Studies reported in the literature on the application of these methods are reviewed in this paper.

  19. Privacy-aware knowledge discovery novel applications and new techniques

    CERN Document Server

    Bonchi, Francesco

    2010-01-01

    Covering research at the frontier of this field, Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques presents state-of-the-art privacy-preserving data mining techniques for application domains, such as medicine and social networks, that face the increasing heterogeneity and complexity of new forms of data. Renowned authorities from prominent organizations not only cover well-established results-they also explore complex domains where privacy issues are generally clear and well defined, but the solutions are still preliminary and in continuous development. Divided into seve

  20. Knowledge based systems advanced concepts, techniques and applications

    CERN Document Server

    1997-01-01

    The field of knowledge-based systems (KBS) has expanded enormously during the last years, and many important techniques and tools are currently available. Applications of KBS range from medicine to engineering and aerospace.This book provides a selected set of state-of-the-art contributions that present advanced techniques, tools and applications. These contributions have been prepared by a group of eminent researchers and professionals in the field.The theoretical topics covered include: knowledge acquisition, machine learning, genetic algorithms, knowledge management and processing under unc

  1. A VIKOR Technique with Applications Based on DEMATEL and ANP

    Science.gov (United States)

    Ou Yang, Yu-Ping; Shieh, How-Ming; Tzeng, Gwo-Hshiung

    In multiple criteria decision making (MCDM) methods, the compromise ranking method (named VIKOR) was introduced as one applicable technique to implement within MCDM. It was developed for multicriteria optimization of complex systems. However, few papers discuss conflicting (competing) criteria with dependence and feedback in the compromise solution method. Therefore, this study proposes and provides applications for a novel model using the VIKOR technique based on DEMATEL and the ANP to solve the problem of conflicting criteria with dependence and feedback. In addition, this research also uses DEMATEL to normalize the unweighted supermatrix of the ANP to suit the real world. An example is also presented to illustrate the proposed method with applications thereof. The results show the proposed method is suitable and effective in real-world applications.

  2. Advances in neutron radiographic techniques and applications: a method for nondestructive testing.

    Science.gov (United States)

    Berger, Harold

    2004-10-01

    A brief history of neutron radiography is presented to set the stage for a discussion of significant neutron radiographic developments and an assessment of future directions for neutron radiography. Specific advances are seen in the use of modern, high dynamic range imaging methods (image plates and flat panels) and for high contrast techniques such as phase contrast, and phase-sensitive imaging. Competition for neutron radiographic inspection may develop as these techniques offer application prospects for X-ray methods.

  3. Advanced magnetron sputtering techniques-principles and applications

    Institute of Scientific and Technical Information of China (English)

    D.G.Teer

    2004-01-01

    @@ The technique of ion plating was introduced by Mattox[1] in 1963. All PVD techniques used for the deposition of hard wear resistant coatings for tribological applications rely on the ion bombardment of the coating during deposition in order to obtain the required coating properties and are all variations of the original ion plating technique. To obtain a dense, hard, wear resistant coating the ion current density during deposition needs to be high, more than 1 mA/cm2 and the energy of the ions should be not more than about 50 eV.

  4. International Conference on Soft Computing Techniques and Engineering Application

    CERN Document Server

    Li, Xiaolong

    2014-01-01

    The main objective of ICSCTEA 2013 is to provide a platform for researchers, engineers and academicians from all over the world to present their research results and development activities in soft computing techniques and engineering application. This conference provides opportunities for them to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration.

  5. Positron emission particle tracking-Application and labelling techniques

    Institute of Scientific and Technical Information of China (English)

    David J.Parker; Xianfeng Fan

    2008-01-01

    The positron emission particle tracking (PEPT) technique has been widely used in science and engineering to obtain detailed information on the motion and flow fields of fluids or granular materials in multiphase systems, for example, fluids in rock cracks, chemical reactors and food processors; dynamic behaviour of granular materials in chemical reactors, granulators, mixers, dryers, rotating kilns and ball mills. The information obtained by the PEPT technique can be used to optimise the design, operational conditions for a wide range of industrial process systems, and to evaluate modelling work. The technique is based on tracking radioactively labelled particles (up to three particles) by detecting the pairs of back-to-back 511 ke V -γ-rays arising from annihilation of emitted positrons. It therefore involves a positron camera, location algorithms for calculating the tracer location and speed, and tracer labelling techniques. This paper will review the particle tracking technique from tracking algorithm, tracer labelling to their application.

  6. Bioanalytical applications of isothermal nucleic acid amplification techniques.

    Science.gov (United States)

    Deng, Huimin; Gao, Zhiqiang

    2015-01-01

    The most popular in vitro nucleic acid amplification techniques like polymerase chain reaction (PCR) including real-time PCR are costly and require thermocycling, rendering them unsuitable for uses at point-of-care. Highly efficient in vitro nucleic acid amplification techniques using simple, portable and low-cost instruments are crucial in disease diagnosis, mutation detection and biodefense. Toward this goal, isothermal amplification techniques that represent a group of attractive in vitro nucleic acid amplification techniques for bioanalysis have been developed. Unlike PCR where polymerases are easily deactivated by thermally labile constituents in a sample, some of the isothermal nucleic acid amplification techniques, such as helicase-dependent amplification and nucleic acid sequence-based amplification, enable the detection of bioanalytes with much simplified protocols and with minimal sample preparations since the entire amplification processes are performed isothermally. This review focuses on the isothermal nucleic acid amplification techniques and their applications in bioanalytical chemistry. Starting off from their amplification mechanisms and significant properties, the adoption of isothermal amplification techniques in bioanalytical chemistry and their future perspectives are discussed. Representative examples illustrating the performance and advantages of each isothermal amplification technique are discussed along with some discussion on the advantages and disadvantages of each technique.

  7. Selected Teacher Performance Specifications Generally Applicable to Teacher Education Curricula.

    Science.gov (United States)

    Johnson, Charles E.; Shearron, Gilbert F.

    This bulletin contains selected lists of teacher performance specifications regarded as generally applicable to teacher education curriculum for undergraduates. ("Performance specifications" are statements which describe particular competencies or competency requirements that a teacher should possess in order to operate at optimum effectiveness in…

  8. Development of an interventional pain management specific instrument for methodologic quality assessment of nonrandomized studies of interventional techniques.

    Science.gov (United States)

    Manchikanti, Laxmaiah; Hirsch, Joshua A; Heavner, James E; Cohen, Steven P; Benyamin, Ramsin M; Sehgal, Nalini; Falco, Frank J E; Vallejo, Ricardo; Onyewu, Obi; Zhu, Jie; Kaye, Alan D; Boswell, Mark V; Helm, Standiford; Candido, Kenneth D; Diwan, Sudhir; Simopoulos, Thomas T; Singh, Vijay; Pampati, Vidyasagar; Racz, Gabor B; Raj, P Prithvi

    2014-01-01

    The major component of a systematic review is assessment of the methodologic quality and bias of randomized and nonrandomized trials. While there are multiple instruments available to assess the methodologic quality and bias for randomized controlled trials (RCTs), there is a lack of extensively utilized instruments for observational studies, specifically for interventional pain management (IPM) techniques. Even Cochrane review criteria for randomized trials is considered not to be a "gold standard," but merely an indication of the current state of the art review methodology. Recently a specific instrument to assess the methodologic quality of randomized trials has been developed for interventional techniques. Our objective was to develop an IPM specific instrument to assess the methodological quality of nonrandomized trials or observational studies of interventional techniques. The item generation for the instrument was based on a definition of quality, to the extent to which the design and conduct of the trial were congruent with the objectives of the study. Applicability was defined as the extent to which procedures produced by the study could be applied using contemporary IPM techniques. Multiple items based on Cochrane review criteria and Interventional Pain Management Techniques - Quality Appraisal of Reliability and Risk of Bias Assessment for Nonrandomized Studies (IPM-QRBNR) were utilized. A total of 16 items were developed which formed the IPM-QRBNR tool. The assessment was performed in multiple stages. The final assessment was 4 nonrandomized studies. The inter-rater agreement was moderate to good for IPM-QRBNR criteria. Limited validity or accuracy assessment of the instrument and the large number of items to be scored were limitations. We have developed a new comprehensive instrument to assess the methodological quality of nonrandomized studies of interventional techniques. This instrument provides extensive information specific to interventional

  9. The development of chromosome microdissection and microcloning technique and its applications in genomic research.

    Science.gov (United States)

    Zhou, Ruo-Nan; Hu, Zan-Min

    2007-03-01

    The technique of chromosome microdissection and microcloning has been developed for more than 20 years. As a bridge between cytogenetics and molecular genetics, it leads to a number of applications: chromosome painting probe isolation, genetic linkage map and physical map construction, and expressed sequence tags generation. During those 20 years, this technique has not only been benefited from other technological advances but also cross-fertilized with other techniques. Today, it becomes a practicality with extensive uses. The purpose of this article is to review the development of this technique and its application in the field of genomic research. Moreover, a new method of generating ESTs of specific chromosomes developed by our lab is introduced. By using this method, the technique of chromosome microdissection and microcloning would be more valuable in the advancement of genomic research.

  10. An introduction to Kundalini yoga meditation techniques that are specific for the treatment of psychiatric disorders.

    Science.gov (United States)

    Shannahoff-Khalsa, David S

    2004-02-01

    The ancient system of Kundalini yoga includes a vast array of meditation techniques and many were discovered to be specific for treating the psychiatric disorders as we know them today. One such technique was found to be specific for treating obsessive-compulsive disorder (OCD), the fourth most common psychiatric disorder, and the tenth most disabling disorder worldwide. Two published clinical trials are described here for treating OCD using a specific Kundalini yoga protocol. This OCD protocol also includes techniques that are useful for a wide range of anxiety disorders, as well as a technique specific for learning to manage fear, one for tranquilizing an angry mind, one for meeting mental challenges, and one for turning negative thoughts into positive thoughts. Part of that protocol is included here and published in detail elsewhere. In addition, a number of other disorder-specific meditation techniques are included here to help bring these tools to the attention of the medical and scientific community. These techniques are specific for phobias, addictive and substance abuse disorders, major depressive disorders, dyslexia, grief, insomnia and other sleep disorders.

  11. A Comparative Study of Ranging Techniques in Deep Space Applications

    Science.gov (United States)

    Cong, Bo; Mao, Nanping; Tao, Xiaohong

    2016-02-01

    In this paper, main ranging techniques in deep space applications are elaborated and analyzed. Their ranging accuracy, acquisition time and complexity are compared. It is shown that the code-tone ranging method has obvious advantage over others in deep space tracking. Start your abstract here...

  12. Applications of nuclear and isotopic techniques in Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Hilmy, N.; Hendranto, K. [Centre for Applications of Isotopes and Radiation, Batan (Indonesia)

    1994-12-31

    Applications of Nuclear and Isotopic Techniques have been developed by the National Atomic Energy Agency (BATAN) since early 1970 in Indonesia. The scope of these applications covers various fields such as agriculture, hydrology, sedimentology and industry. Some applications of tracer techniques in industry which have been done such as measurement of homogeneity of mixing process in fertiliser and paper factory, residence time distribution in gold processing plant, mercury inventory in caustic soda plant, enhanced oil recovery in oil production wells, leakage investigation in dust chamber of fertiliser plant and blockage of pipeline, are presented in this paper. In the field of NDT by radiographic technique, BATAN regularly conducts training courses and also issues licences for Level I and II. Some applications of nuclear techniques in agriculture such as mutation breeding, animal production and animal health have shown the potential of radiation in creating variability as a basis for varietal improvements in several food crop species, the potential of using isotopes as tracers in the studies on metabolism, particularly in relation to the efficiency of rumen fermentative digestion and biological evaluation of locally available feedstuffs from agricultural and agro-industrial byproducts. So far, four varieties of nice, two varieties of soybean, and one variety of mungbean have been officially approved for release, and one formulation of feed supplement utilizing locally available agricultural and agro-industrial byproducts has been established and used for cattle and goats. In animal health, a radiovaccine against coccidiosis in poultry has been produced and used routinely.

  13. 48 CFR 9904.403-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    .... 9904.403-50 Section 9904.403-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.403-50 Techniques for application. (a)(1) Separate... ascertain. In these latter cases the basis for allocation shall be a measurement of the output of...

  14. 48 CFR 9904.418-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    .... 9904.418-50 Section 9904.418-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.418-50 Techniques for application. (a) Determination of direct cost and indirect cost. (1) The business unit's written policy classifying costs as direct...

  15. 48 CFR 9904.411-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    .... 9904.411-50 Section 9904.411-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.411-50 Techniques for application. (a) Material cost...) The method of computation used for any inventory costing method selected pursuant to the provisions...

  16. 48 CFR 9904.406-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ...) When a transitional cost accounting period is required under the provisions of 9904.406-40(a)(3), the.... 9904.406-50 Section 9904.406-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.406-50 Techniques for application. (a) The cost of...

  17. 48 CFR 9904.412-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... pursuant to the provisions of this Standard. The accounting treatment to be afforded to such gains and.... 9904.412-50 Section 9904.412-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.412-50 Techniques for application. (a) Components...

  18. Application of Data Collection Techniques by Human Performance Technology Practitioners

    Science.gov (United States)

    Duan, Minjing

    2011-01-01

    By content-analyzing 22 published cases from a variety of professional and academic books and journals, this study examines the status quo of human performance technology (HPT) practitioners' application of five major data collection techniques in their everyday work: questionnaire, interview, focus group, observation, and document collection. The…

  19. Scanning tunneling microscopy II further applications and related scanning techniques

    CERN Document Server

    Güntherodt, Hans-Joachim

    1992-01-01

    Scanning Tunneling Microscopy II, like its predecessor, presents detailed and comprehensive accounts of the basic principles and broad range of applications of STM and related scanning probe techniques. The applications discussed in this volume come predominantly from the fields of electrochemistry and biology. In contrast to those described in Vol. I, these sudies may be performed in air and in liquids. The extensions of the basic technique to map other interactions are described inchapters on scanning force microscopy, magnetic force microscopy, scanning near-field optical microscopy, together with a survey of other related techniques. Also described here is the use of a scanning proximal probe for surface modification. Togehter, the two volumes give a comprehensive account of experimental aspcets of STM. They provide essentialreading and reference material for all students and researchers involvedin this field.

  20. Scanning tunneling microscopy II further applications and related scanning techniques

    CERN Document Server

    Güntherodt, Hans-Joachim

    1995-01-01

    Scanning Tunneling Microscopy II, like its predecessor, presents detailed and comprehensive accounts of the basic principles and broad range of applications of STM and related scanning probe techniques. The applications discussed in this volume come predominantly from the fields of electrochemistry and biology. In contrast to those described in STM I, these studies may be performed in air and in liquids. The extensions of the basic technique to map other interactions are described in chapters on scanning force microscopy, magnetic force microscopy, and scanning near-field optical microscopy, together with a survey of other related techniques. Also described here is the use of a scanning proximal probe for surface modification. Together, the two volumes give a comprehensive account of experimental aspects of STM. They provide essential reading and reference material for all students and researchers involved in this field. In this second edition the text has been updated and new methods are discussed.

  1. Usability evaluation techniques in mobile commerce applications: A systematic review

    Science.gov (United States)

    Hussain, Azham; Mkpojiogu, Emmanuel O. C.

    2016-08-01

    Obviously, there are a number of literatures concerning the usability of mobile commerce (m-commerce) applications and related areas, but they do not adequately provide knowledge about usability techniques used in most of the empirical usability evaluation for m-commerce application. Therefore, this paper is aimed at producing the usability techniques frequently used in the aspect of usability evaluation for m-commerce applications. To achieve the stated objective, systematic literature review was employed. Sixty seven papers were downloaded in usability evaluation for m-commerce and related areas; twenty one most relevant studies were selected for review in order to extract the appropriate information. The results from the review shows that heuristic evaluation, formal test and think aloud methods are the most commonly used methods in m-commerce application in comparison to cognitive walkthrough and the informal test methods. Moreover, most of the studies applied control experiment (33.3% of the total studies); other studies that applied case study for usability evaluation are 14.28%. The results from this paper provide additional knowledge to the usability practitioners and research community for the current state and use of usability techniques in m-commerce application.

  2. The microwave palaeointensity technique and its application to lava

    CERN Document Server

    Hill, M J

    2000-01-01

    application is required at each power step thus removing the need for accurate reproducibility of absorbed microwave power and also reducing experimental time. This method as well as a previous method developed for use with ceramic samples are described and discussed. The microwave palaeointensity technique has been used successfully in three palaeomagnetic studies (that include rock magnetic and directional analyses). These are a study of historic lava from Mt. Etna, Sicily, a detailed through the flow study of the 1960 Kilauea lava flow, Hawaii and a study of Tertiary Australian lava. Palaeointensity results are compared to observatory records and / or results of previous studies using conventional techniques. The research undertaken, described in this thesis, demonstrates that the microwave palaeointensity technique is a viable technique for use with lava. This enables greater confidence that any palaeointensity results obtained are not affected by sample alteration during experimentation. The suitability ...

  3. Industrial application of formal models generated from domain specific languages

    NARCIS (Netherlands)

    Hooman, J.

    2016-01-01

    Domain Specific Languages (DSLs) provide a lightweight approach to incorporate formal techniques into the industrial workflow. From DSL instances, formal models and other artefacts can be generated, such as simulation models and code. Having a single source for all artefacts improves maintenance and

  4. RF circuit design techniques for MF-UHF applications

    CERN Document Server

    Eroglu, Abdullah

    2013-01-01

    Magnetic resonance imaging, semiconductor processing, and RFID are some of the critical applications within the medium frequency (MF) to ultrahigh frequency (UHF) range that require RF designers to have a solid understanding of analytical and experimental RF techniques. Designers need to be able to design components and devices cost effectively, and integrate them with high efficiency, minimal loss, and required power. Computer-aided design (CAD) tools also play an important part in helping to reduce costs and improve accuracy through optimization. RF Circuit Design Techniques for MF-UHF Appli

  5. Image and video compression fundamentals, techniques, and applications

    CERN Document Server

    Joshi, Madhuri A; Dandawate, Yogesh H; Joshi, Kalyani R; Metkar, Shilpa P

    2014-01-01

    Image and video signals require large transmission bandwidth and storage, leading to high costs. The data must be compressed without a loss or with a small loss of quality. Thus, efficient image and video compression algorithms play a significant role in the storage and transmission of data.Image and Video Compression: Fundamentals, Techniques, and Applications explains the major techniques for image and video compression and demonstrates their practical implementation using MATLAB® programs. Designed for students, researchers, and practicing engineers, the book presents both basic principles

  6. Bladesmithing with Murray Carter modern application of traditional techniques

    CERN Document Server

    Carter, Murray

    2011-01-01

    Bladesmithing with Murray Carter provides the reader with an in-depth look into traditional Japanese Cutlery forging techniques and their modern applications. A non-stop flow of inquiries to Murray has prompted him to reveal the secret techniques learned during 18 years in Japan, where he lived and worked as a village bladesmith. He now shares this wealth of information for the benefit of the curious reader and Japanese knife enthusiast alike. Owners of nearly 15,000 of Murray's knives will be delighted to see a comprehensive book written by the knives' creator. Features: 250+ dazzling, f

  7. Review of optimization techniques of polygeneration systems for building applications

    Science.gov (United States)

    Y, Rong A.; Y, Su; R, Lahdelma

    2016-08-01

    Polygeneration means simultaneous production of two or more energy products in a single integrated process. Polygeneration is an energy-efficient technology and plays an important role in transition into future low-carbon energy systems. It can find wide applications in utilities, different types of industrial sectors and building sectors. This paper mainly focus on polygeneration applications in building sectors. The scales of polygeneration systems in building sectors range from the micro-level for a single home building to the large- level for residential districts. Also the development of polygeneration microgrid is related to building applications. The paper aims at giving a comprehensive review for optimization techniques for designing, synthesizing and operating different types of polygeneration systems for building applications.

  8. Compilation Techniques Specific for a Hardware Cryptography-Embedded Multimedia Mobile Processor

    Directory of Open Access Journals (Sweden)

    Masa-aki FUKASE

    2007-12-01

    Full Text Available The development of single chip VLSI processors is the key technology of ever growing pervasive computing to answer overall demands for usability, mobility, speed, security, etc. We have so far developed a hardware cryptography-embedded multimedia mobile processor architecture, HCgorilla. Since HCgorilla integrates a wide range of techniques from architectures to applications and languages, one-sided design approach is not always useful. HCgorilla needs more complicated strategy, that is, hardware/software (H/S codesign. Thus, we exploit the software support of HCgorilla composed of a Java interface and parallelizing compilers. They are assumed to be installed in servers in order to reduce the load and increase the performance of HCgorilla-embedded clients. Since compilers are the essence of software's responsibility, we focus in this article on our recent results about the design, specifications, and prototyping of parallelizing compilers for HCgorilla. The parallelizing compilers are composed of a multicore compiler and a LIW compiler. They are specified to abstract parallelism from executable serial codes or the Java interface output and output the codes executable in parallel by HCgorilla. The prototyping compilers are written in Java. The evaluation by using an arithmetic test program shows the reasonability of the prototyping compilers compared with hand compilers.

  9. Compilation Techniques Specific for a Hardware Cryptography-Embedded Multimedia Mobile Processor

    Directory of Open Access Journals (Sweden)

    Masa-aki FUKASE

    2007-12-01

    Full Text Available The development of single chip VLSI processors is the key technology of ever growing pervasive computing to answer overall demands for usability, mobility, speed, security, etc. We have so far developed a hardware cryptography-embedded multimedia mobile processor architecture, HCgorilla. Since HCgorilla integrates a wide range of techniques from architectures to applications and languages, one-sided design approach is not always useful. HCgorilla needs more complicated strategy, that is, hardware/software (H/S codesign. Thus, we exploit the software support of HCgorilla composed of a Java interface and parallelizing compilers. They are assumed to be installed in servers in order to reduce the load and increase the performance of HCgorilla-embedded clients. Since compilers are the essence of software's responsibility, we focus in this article on our recent results about the design, specifications, and prototyping of parallelizing compilers for HCgorilla. The parallelizing compilers are composed of a multicore compiler and a LIW compiler. They are specified to abstract parallelism from executable serial codes or the Java interface output and output the codes executable in parallel by HCgorilla. The prototyping compilers are written in Java. The evaluation by using an arithmetic test program shows the reasonability of the prototyping compilers compared with hand compilers.

  10. Techniques and applications of endoscopic spine surgery. Part I:overview of current techniques

    Institute of Scientific and Technical Information of China (English)

    Kai-Xuan Liu; MD; PhD

    2013-01-01

    Background Spinal pain is a serious health and social-economic problem. Endoscopic spine surgery as a treatment option for spinal pain has gained tremendous attention and growth in the past 2 decades, and a variety of endoscopic techniques have been invented to treat a wide range of spinal conditions. Purposes The purposes of this 2-part review article are to 1 ) overview the published techniques of endoscopic spine surgery, 2 ) summarize the applications of these techniques in treating various spinal conditions, and 3 ) evaluate the clinical evidence of the safety and effectiveness of these endoscopic techniques in treating some of the most common spinal conditions. The first part of the review article provides an overview of currently most commonly used techniques. Methods We searched the PubMed database for publications concerning endoscopic spine surgery and reviewed the relevant articles published in the English language. Results Discectomy and foraminotomy are the most common types of spine surgery that can currently be done endoscopically. Endoscopic techniques have been used to treat a wide range of spinal disorders located in the lumbar, cervical, as well as the thoracic regions of the spine.

  11. Commercial Application of Technique for Removing Sulfates from Reforming Catalyst

    Institute of Scientific and Technical Information of China (English)

    JiChangqing

    2002-01-01

    In the course of reduction of reforming catalyst by not hydrogen a certain amount of chlorine containing compounds is added to the recycle hydrogen to facilitate the reduction of sulfates.The outcome of commercial application of this technique has revealed that the procedure of "regeneration by chlorination→reduction→sulfate removal→sulfiding and oil feed-in"aimed at sulate removal is very simple and can recover the reaction activity of reforming catalyst after having been poisoned by sulfates.This procedure can be disseminated for application in refineries.

  12. [Application of molecular marker techniques in invasion ecology].

    Science.gov (United States)

    Chu, Dong; Zhang, You-jun; Wan, Fang-hao

    2007-06-01

    Alien invasive species can cause huge economic loss in agricultural and forestry production, and threaten biodiversity and human health. The research of invasion ecology is of significance in understanding the invasion mechanisms of alien invasive species and in developing corresponding sustainable control methods. Molecular marker is regarded as a useful tool in approaching some essential issues in the research of invasion ecology. In this paper, the applications of molecular marker techniques in the studies of identification, geographic distribution, invasive source, spread pattern, genetic variation, hybridization, and gene introgression of alien invasive species were reviewed, and the application prospects were discussed.

  13. Cloud computing and digital media fundamentals, techniques, and applications

    CERN Document Server

    Li, Kuan-Ching; Shih, Timothy K

    2014-01-01

    Cloud Computing and Digital Media: Fundamentals, Techniques, and Applications presents the fundamentals of cloud and media infrastructure, novel technologies that integrate digital media with cloud computing, and real-world applications that exemplify the potential of cloud computing for next-generation digital media. It brings together technologies for media/data communication, elastic media/data storage, security, authentication, cross-network media/data fusion, interdevice media interaction/reaction, data centers, PaaS, SaaS, and more.The book covers resource optimization for multimedia clo

  14. Literature survey of heat transfer enhancement techniques in refrigeration applications

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, M.K.; Shome, B. [Rensselaer Polytechnic Inst., Troy, NY (United States). Dept. of Mechanical Engineering, Aeronautical Engineering and Mechanics

    1994-05-01

    A survey has been performed of the technical and patent literature on enhanced heat transfer of refrigerants in pool boiling, forced convection evaporation, and condensation. Extensive bibliographies of the technical literature and patents are given. Many passive and active techniques were examined for pure refrigerants, refrigerant-oil mixtures, and refrigerant mixtures. The citations were categorized according to enhancement technique, heat transfer mode, and tube or shell side focus. The effects of the enhancement techniques relative to smooth and/or pure refrigerants were illustrated through the discussion of selected papers. Patented enhancement techniques also are discussed. Enhanced heat transfer has demonstrated significant improvements in performance in many refrigerant applications. However, refrigerant mixtures and refrigerant-oil mixtures have not been studied extensively; no research has been performed with enhanced refrigerant mixtures with oil. Most studies have been of the parametric type; there has been inadequate examination of the fundamental processes governing enhanced refrigerant heat transfer, but some modeling is being done and correlations developed. It is clear that an enhancement technique must be optimized for the refrigerant and operating condition. Fundamental processes governing the heat transfer must be examined if models for enhancement techniques are to be developed; these models could provide the method to optimize a surface. Refrigerant mixtures, with and without oil present, must be studied with enhancement devices; there is too little known to be able to estimate the effects of mixtures (particularly NARMs) with enhanced heat transfer. Other conclusions and recommendations are offered.

  15. Single-cell epigenomics: techniques and emerging applications.

    Science.gov (United States)

    Schwartzman, Omer; Tanay, Amos

    2015-12-01

    Epigenomics is the study of the physical modifications, associations and conformations of genomic DNA sequences, with the aim of linking these with epigenetic memory, cellular identity and tissue-specific functions. While current techniques in the field are characterizing the average epigenomic features across large cell ensembles, the increasing interest in the epigenetics within complex and heterogeneous tissues is driving the development of single-cell epigenomics. We review emerging single-cell methods for capturing DNA methylation, chromatin accessibility, histone modifications, chromosome conformation and replication dynamics. Together, these techniques are rapidly becoming a powerful tool in studies of cellular plasticity and diversity, as seen in stem cells and cancer.

  16. Applications of lattice QCD techniques for condensed matter systems

    Science.gov (United States)

    Buividovich, P. V.; Ulybyshev, M. V.

    2016-08-01

    We review the application of lattice QCD techniques, most notably the Hybrid Monte Carlo (HMC) simulations, to first-principle study of tight-binding models of crystalline solids with strong inter-electron interactions. After providing a basic introduction into the HMC algorithm as applied to condensed matter systems, we review HMC simulations of graphene, which in the recent years have helped to understand the semimetal behavior of clean suspended graphene at the quantitative level. We also briefly summarize other novel physical results obtained in these simulations. Then we comment on the applicability of hybrid Monte Carlo to topological insulators and Dirac and Weyl semimetals and highlight some of the relevant open physical problems. Finally, we also touch upon the lattice strong-coupling expansion technique as applied to condensed matter systems.

  17. Application of thermal analysis techniques in activated carbon production

    Science.gov (United States)

    Donnals, G.L.; DeBarr, J.A.; Rostam-Abadi, M.; Lizzio, A.A.; Brady, T.A.

    1996-01-01

    Thermal analysis techniques have been used at the ISGS as an aid in the development and characterization of carbon adsorbents. Promising adsorbents from fly ash, tires, and Illinois coals have been produced for various applications. Process conditions determined in the preparation of gram quantities of carbons were used as guides in the preparation of larger samples. TG techniques developed to characterize the carbon adsorbents included the measurement of the kinetics of SO2 adsorption, the performance of rapid proximate analyses, and the determination of equilibrium methane adsorption capacities. Thermal regeneration of carbons was assessed by TG to predict the life cycle of carbon adsorbents in different applications. TPD was used to determine the nature of surface functional groups and their effect on a carbon's adsorption properties.

  18. APPLICATION OF NOVEL NEUTRON CORRELATION TECHNIQUES TO NUCLEAR MATERIAL MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Sale, K

    2006-06-09

    Confirmation of the fissile mass of a system containing plutonium can be done using neutron multiplicity techniques. This can be accomplished with a detector system that is smaller and less costly than a standard neutron multiplicity counter (NMC). Also the fissile mass of a uranium containing system can be confirmed by passive means. Recent work at Lawrence Livermore National Laboratory has demonstrated that simple slab neutron detectors and a novel approach to data acquisition and analysis can be used to make an accurate measurement of the mass of fissile materials. Purely passive measurement of kilogram quantities of highly enriched uranium (HEU) have also been shown to be feasible. In this paper we discuss calculational tools for assessing the application of these techniques to fissile material transparency regimes. The tools required to adequately model the correlations and their application will be discussed.

  19. Performance of fertigation technique for phosphorus application in cotton

    Directory of Open Access Journals (Sweden)

    M. Aslam

    2009-05-01

    Full Text Available Low native soil phosphorus availability coupled with poor utilization of added phosphorus is one of the major constraints limiting the productivity of the crops. With a view of addressing this issue, field studies were conducted to compare the relative efficacy of broadcast and fertigation techniques for phosphorus application during 2005-2006 using cotton as a test crop. Two methods of phosphorus application i.e. broadcast and fertigation were evaluated using five levels of P2O5 (0, 30, 45, 60 and 75 kg P2O5 ha -1. Fertigation showed an edge over broadcast method at all levels of phosphorus application. The highest seed cotton yield was recorded with 75 kg P2O5 ha-1. Fertilizer phosphorus applied at the rate of 60 kg ha-1 through fertigation produced 3.4 tons ha-1 of seed cotton yield, which was statistically identical to 3.3 tons recorded with 75 kg ha-1 of broadcast phosphorus. Agronomic performance of phosphorus was influenced considerably by either method of fertilizer application. The seed cotton yield per kg of fertigation phosphorus was 48% higher than the corresponding broadcast application. The results of these studies showed that fertigation was the most efficient method of phosphorus application compared with the conventional broadcast application of fertilizers.

  20. Internet tomography an introduction to concepts, techniques, tools and applications

    CERN Document Server

    Moloisane, Abia; O’Droma, Máirtín

    2013-01-01

    Internet tomography, introduced from basic principles through to techniques, tools and applications, is the subject of this book. The design of Internet Tomography Measurement Systems (ITMS) aimed at mapping the Internet performance profile spatially and temporally over paths between probing stations is a particular focus.The Internet Tomography Measurement System design criteria addressed include:Minimally-invasive, independent and autonomous, active or passive measurement;Flexibility and scalability;Capability of targeting local, regional and global Internet paths and underlying IP networks;

  1. Spray drying technique: II. Current applications in pharmaceutical technology.

    Science.gov (United States)

    Sollohub, Krzysztof; Cal, Krzysztof

    2010-02-01

    This review presents current applications of spray drying in pharmaceutical technology. The topics discussed include the obtention of excipients and cospray dried composites, methods for increasing the aqueous solubility and bioavailability of active substances, and modified release profiles from spray-dried particles. This review also describes the use of the spray drying technique in the context of biological therapies, such as the spray drying of proteins, inhalable powders, and viable organisms, and the modification of the physical properties of dry plant extracts.

  2. An introduction to synchrotron radiation techniques and applications

    CERN Document Server

    Willmott, Philip

    2011-01-01

    This book introduces the reader to the basic concepts of the generation and manipulation of synchrotron light, its interaction with matter, and the application of synchrotron light in the “classical” techniques, while including some of the most modern technological developments. As much as possible, complicated mathematical derivations and formulas are avoided. A more heuristic approach is adopted, whereby the general physical reasoning behind the equations is highlighted.

  3. Storing files in a parallel computing system based on user or application specification

    Science.gov (United States)

    Faibish, Sorin; Bent, John M.; Nick, Jeffrey M.; Grider, Gary; Torres, Aaron

    2016-03-29

    Techniques are provided for storing files in a parallel computing system based on a user-specification. A plurality of files generated by a distributed application in a parallel computing system are stored by obtaining a specification from the distributed application indicating how the plurality of files should be stored; and storing one or more of the plurality of files in one or more storage nodes of a multi-tier storage system based on the specification. The plurality of files comprise a plurality of complete files and/or a plurality of sub-files. The specification can optionally be processed by a daemon executing on one or more nodes in a multi-tier storage system. The specification indicates how the plurality of files should be stored, for example, identifying one or more storage nodes where the plurality of files should be stored.

  4. Hyperspherical harmonics expansion techniques application to problems in physics

    CERN Document Server

    Das, Tapan Kumar

    2016-01-01

    The book provides a generalized theoretical technique for solving the fewbody Schrödinger equation. Straight forward approaches to solve it in terms of position vectors of constituent particles and using standard mathematical techniques become too cumbersome and inconvenient when the system contains more than two particles. The introduction of Jacobi vectors, hyperspherical variables and hyperspherical harmonics as an expansion basis is an elegant way to tackle systematically the problem of an increasing number of interacting particles. Analytic expressions for hyperspherical harmonics, appropriate symmetrisation of the wave function under exchange of identical particles and calculation of matrix elements of the interaction have been presented. Applications of this technique to various problems of physics have been discussed. In spite of straight forward generalization of the mathematical tools for increasing number of particles, the method becomes computationally difficult for more than a few particles. Hen...

  5. On the Application of TLS Techniques to AC Electrical Drives

    Directory of Open Access Journals (Sweden)

    M. Cirrincione

    2005-03-01

    Full Text Available This paper deals with the application of a new neuron, the TLS EXIN neuron, to AC induction motor drives. In particular, it addresses two important subjects of AC induction motor drives: the on-line estimation of the electrical parameters of the machine and the speed estimation in sensorless drives. On this basis, this work summarizes the parameter estimation and sensorless techniques already developed by the authors over these last few years, all based on the TLS EXIN. With regard to sensorless, two techniques are proposed: one based on the MRAS and the other based on the full-order Luenberger observer. The work show some of the most significant results obtained by the authors in these fields and stresses the important potentiality of this new neural technique in AC induction machine drives.

  6. Imaging of the hip and bony pelvis. Techniques and applications

    Energy Technology Data Exchange (ETDEWEB)

    Davies, A.M. [Royal Orthopaedic Hospital, Birmingham (United Kingdom). MRI Centre; Johnson, K.J. [Princess of Wales Birmingham Children' s Hospital (United Kingdom); Whitehouse, R.W. (eds.) [Manchester Royal Infirmary (United Kingdom). Dept. of Clinical Radiology

    2006-07-01

    This is a comprehensive textbook on imaging of the bony pelvis and hip joint that provides a detailed description of the techniques and imaging findings relevant to this complex anatomical region. In the first part of the book, the various techniques and procedures employed for imaging the pelvis and hip are discussed in detail. The second part of the book documents the application of these techniques to the diverse clinical problems and diseases encountered. Among the many topics addressed are congenital and developmental disorders including developmental dysplasia of the hip, irritable hip and septic arthritis, Perthes' disease and avascular necrosis, slipped upper femoral epiphysis, bony and soft tissue trauma, arthritis, tumours and hip prostheses. Each chapter is written by an acknowledged expert in the field, and a wealth of illustrative material is included. This book will be of great value to musculoskeletal and general radiologists, orthopaedic surgeons and rheumatologists. (orig.)

  7. Application of the electrosorption technique to remove Metribuzin pesticide.

    Science.gov (United States)

    Kitous, O; Cheikh, A; Lounici, H; Grib, H; Pauss, A; Mameri, N

    2009-01-30

    The present work deals with the removal of Metribuzin from aqueous solutions in a batch and continuous mode using electrosorption technique. This technique is based on the combination of two processes: the adsorption of Metribuzin into activated granular carbon (GAC) column and the application of the electrochemical potential. The effects of various experimental parameters (electrochemical potential, volumetric flow rate and initial Metribuzin concentration) on the removal efficiency were investigated. The pesticide sorption capacity at the breakthrough point of the GAC column reached 22 mg(pesticide)g(GAC)(-1). It was increased by more than 100% when the desired electrical potential (-50 mV/SCE) was applied in comparison with the conventional GAC column in similar experimental conditions without electrical potential. Evenmore, the electrosorption technique reduced considerably the drastic decrease encountered when passing from batch mode to continuous column mode.

  8. Application of supercritical fluid to separation techniques; Chorinkai ryutai no bunri gijutsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Minamino, Y.; Aki, T. [Mitsubishi Kakoki Kaisha Ltd., Tokyo (Japan)

    1994-09-05

    The application of supercritical fluid on separation techniques and its problems are reviewed. The application is at a standstill contrary to large expectation for it except component extraction from natural foods such as caffeine removal from coffee. Various problems are thus pointed out to be solved as follows; a study on new applications other than substitutional use for organic solvents, cost reduction, a study on new safe advanced fluids suitable for specific objects other than CO2, and combination with other several separation techniques. The new practical applications of supercritical fluid expected in the near future are as follows; low-cost mass production of antibodies by use of the immunity system of hens, drying of porous bodies intercalated in aqueous solution, removal of residual unreacted monomers and organic solvents from medical polymers, development of supercritical chromatographic equipment possible to separate pure functional food materials, and analytical extraction of functional groups including hetero atoms from harmful substances. 6 refs., 2 figs., 2 tabs.

  9. Application of altitude control techniques for low altitude earth satellites

    Science.gov (United States)

    Nickerson, K. G.; Herder, R. W.; Glass, A. B.; Cooley, J. L.

    1977-01-01

    The applications sensors of many low altitude earth satellites designed for recording surface or atmospheric data require near zero orbital eccentricities for maximum usefulness. Coverage patterns and altitude profiles require specified values of orbit semimajor axis. Certain initial combinations of semimajor axis, eccentricity, and argument of perigee can produce a so called 'frozen orbit' and minimum altitude variation which enhances sensor coverage. This paper develops information on frozen orbits and minimum altitude variation for all inclinations, generalizing previous results. In the altitude regions where most of these satellites function (between 200 and 1000 kilometers) strong atmospheric drag effects influence the evolution of the initial orbits. Active orbital maneuver control techniques to correct evolution of orbit parameters while minimizing the frequency of maneuvers are presented. The paper presents the application of theoretical techniques for control of near frozen orbits and expands upon the methods useful for simultaneously targeting several inplane orbital parameters. The applications of these techniques are illustrated by performance results from the Atmosphere Explorer (AE-3 and -5) missions and in preflight maneuver analysis and plans for the Seasat Oceanographic Satellite.

  10. [Application of cell co-culture techniques in medical studies].

    Science.gov (United States)

    Luo, Yun; Sun, Gui-Bo; Qin, Meng; Yao, Fan; Sun, Xiao-Bo

    2012-11-01

    As the cell co-culture techniques can better imitate an in vivo environment, it is helpful in observing the interactions among cells and between cells and the culture environment, exploring the effect mechanisms of drugs and their possible targets and filling the gaps between the mono-layer cell culture and the whole animal experiments. In recently years, they has attracted much more attention from the medical sector, and thus becoming one of research hotspots in drug research and development and bio-pharmaceutical fields. The cell co-culture techniques, including direct and indirect methods, are mainly used for studying pathological basis, new-type treatment methods and drug activity screening. Existing cell co-culture techniques are used for more pharmacological studies on single drug and less studies on interaction of combined drugs, such as collaborative compatibility and attenuation and synergistic effect among traditional Chinese medicines (TCMs). In line with the action characteristics of multi-component and multi-target, the cell co-culture techniques provide certain reference value for future studies on the effect and mechanism of combined TCMs on organisms as well as new methods for studies on TCMs and their compounds. This essay summarizes cell co-culture methods and their application and look into the future of their application in studies on TCMs and compounds.

  11. Automated Design of Application-Specific Smart Camera Architectures

    NARCIS (Netherlands)

    Caarls, W.

    2008-01-01

    Parallel heterogeneous multiprocessor systems are often shunned in embedded system design, not only because of their design complexity but because of the programming burden. Programs for such systems are architecture-dependent: the application developer needs architecture-specific knowledge to imple

  12. Internet factories: Creating application-specific networks on-demand

    NARCIS (Netherlands)

    Strijkers, R.J.; Makkes, M.X.; Laat, C. de; Meijer, R.J.

    2014-01-01

    We introduce the concept of Internet factories. Internet factories structure the task of creating and managing application-specific overlay networks using infrastructure-as-a-service clouds. We describe the Internet factory architecture and report on a proof of concept with three examples that progr

  13. Application software, domain-specific languages, and language design assistants

    NARCIS (Netherlands)

    J. Heering (Jan)

    2000-01-01

    textabstractWhile application software does the real work, domain-specific languages (DSLs) are tools to help produce it efficiently, and language design assistants in turn are meta-tools to help produce DSLs quickly. DSLs are already in wide use (HTML for web pages, Excel macros for spreadsheet

  14. Virtual 3d City Modeling: Techniques and Applications

    Science.gov (United States)

    Singh, S. P.; Jain, K.; Mandla, V. R.

    2013-08-01

    3D city model is a digital representation of the Earth's surface and it's related objects such as Building, Tree, Vegetation, and some manmade feature belonging to urban area. There are various terms used for 3D city models such as "Cybertown", "Cybercity", "Virtual City", or "Digital City". 3D city models are basically a computerized or digital model of a city contains the graphic representation of buildings and other objects in 2.5 or 3D. Generally three main Geomatics approach are using for Virtual 3-D City models generation, in first approach, researcher are using Conventional techniques such as Vector Map data, DEM, Aerial images, second approach are based on High resolution satellite images with LASER scanning, In third method, many researcher are using Terrestrial images by using Close Range Photogrammetry with DSM & Texture mapping. We start this paper from the introduction of various Geomatics techniques for 3D City modeling. These techniques divided in to two main categories: one is based on Automation (Automatic, Semi-automatic and Manual methods), and another is Based on Data input techniques (one is Photogrammetry, another is Laser Techniques). After details study of this, finally in short, we are trying to give the conclusions of this study. In the last, we are trying to give the conclusions of this research paper and also giving a short view for justification and analysis, and present trend for 3D City modeling. This paper gives an overview about the Techniques related with "Generation of Virtual 3-D City models using Geomatics Techniques" and the Applications of Virtual 3D City models. Photogrammetry, (Close range, Aerial, Satellite), Lasergrammetry, GPS, or combination of these modern Geomatics techniques play a major role to create a virtual 3-D City model. Each and every techniques and method has some advantages and some drawbacks. Point cloud model is a modern trend for virtual 3-D city model. Photo-realistic, Scalable, Geo-referenced virtual 3

  15. Hardware Compilation of Application-Specific Memory-Access Interconnect

    DEFF Research Database (Denmark)

    Venkataramani, Girish; Bjerregaard, Tobias; Chelcea, Tiberiu

    2006-01-01

    A major obstacle to successful high-level synthesis (HLS) of large-scale application-specified integrated circuit systems is the presence of memory accesses to a shared-memory subsystem. The latency to access memory is often not statically predictable, which creates problems for scheduling operat...... memory consistency. Postlayout experiments demonstrate that SOMA's application-specific MAN construction significantly improves power and performance for a range of benchmarks.......A major obstacle to successful high-level synthesis (HLS) of large-scale application-specified integrated circuit systems is the presence of memory accesses to a shared-memory subsystem. The latency to access memory is often not statically predictable, which creates problems for scheduling...... operations dependent on memory reads. More fundamental is that dependences between accesses may not be statically provable (e.g., if the specification language permits pointers), which introduces memory-consistency problems. Addressing these issues with static scheduling results in overly conservative...

  16. MEMS-Based Power Generation Techniques for Implantable Biosensing Applications

    Directory of Open Access Journals (Sweden)

    Jonathan Lueke

    2011-01-01

    Full Text Available Implantable biosensing is attractive for both medical monitoring and diagnostic applications. It is possible to monitor phenomena such as physical loads on joints or implants, vital signs, or osseointegration in vivo and in real time. Microelectromechanical (MEMS-based generation techniques can allow for the autonomous operation of implantable biosensors by generating electrical power to replace or supplement existing battery-based power systems. By supplementing existing battery-based power systems for implantable biosensors, the operational lifetime of the sensor is increased. In addition, the potential for a greater amount of available power allows additional components to be added to the biosensing module, such as computational and wireless and components, improving functionality and performance of the biosensor. Photovoltaic, thermovoltaic, micro fuel cell, electrostatic, electromagnetic, and piezoelectric based generation schemes are evaluated in this paper for applicability for implantable biosensing. MEMS-based generation techniques that harvest ambient energy, such as vibration, are much better suited for implantable biosensing applications than fuel-based approaches, producing up to milliwatts of electrical power. High power density MEMS-based approaches, such as piezoelectric and electromagnetic schemes, allow for supplemental and replacement power schemes for biosensing applications to improve device capabilities and performance. In addition, this may allow for the biosensor to be further miniaturized, reducing the need for relatively large batteries with respect to device size. This would cause the implanted biosensor to be less invasive, increasing the quality of care received by the patient.

  17. Elements of slow-neutron scattering basics, techniques, and applications

    CERN Document Server

    Carpenter, J M

    2015-01-01

    Providing a comprehensive and up-to-date introduction to the theory and applications of slow-neutron scattering, this detailed book equips readers with the fundamental principles of neutron studies, including the background and evolving development of neutron sources, facility design, neutron scattering instrumentation and techniques, and applications in materials phenomena. Drawing on the authors' extensive experience in this field, this text explores the implications of slow-neutron research in greater depth and breadth than ever before in an accessible yet rigorous manner suitable for both students and researchers in the fields of physics, biology, and materials engineering. Through pedagogical examples and in-depth discussion, readers will be able to grasp the full scope of the field of neutron scattering, from theoretical background through to practical, scientific applications.

  18. Development of Plant Application Technique of Low Dose Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Byung Yeoup; Kim, Jae Sung; Lim, Yong Taek (and others)

    2007-07-15

    The project was carried out to achieve three aims. First, development of application techniques of cell-stimulating effects by low-dose radiation. Following irradiation with gamma-rays of low doses, beneficial effects in crop germination, early growth, and yield were investigated using various plant species and experimental approaches. For the actual field application, corroborative studies were also carried out with a few concerned experimental stations and farmers. Moreover, we attempted to establish a new technique of cell cultivation for industrial mass-production of shikonin, a medicinal compound from Lithospermum erythrorhizon and thereby suggested new application fields for application techniques of low-dose radiation. Second, elucidation of action mechanisms of ionizing radiation in plants. By investigating changes in plant photosynthesis and physiological metabolism, we attempted to elucidate physiological activity-stimulating effects of low-dose radiation and to search for radiation-adaptive cellular components. Besides, analyses of biochemical and molecular biological mechanisms for stimulus-stimulating effects of low-dose radiation were accomplished by examining genes and proteins inducible by low-dose radiation. Third, development of functional crop plants using radiation-resistant factors. Changes in stress-tolerance of plants against environmental stress factors such as light, temperature, salinity and UV-B stress after exposed to low-dose gamma-rays were investigated. Concerned reactive oxygen species, antioxidative enzymes, and antioxidants were also analyzed to develop high value-added and environment-friendly functional plants using radiation-resistant factors. These researches are important to elucidate biological activities increased by low-dose radiation and help to provide leading technologies for improvement of domestic productivity in agriculture and development of high value-added genetic resources.

  19. Assessing specific gravity of young Eucalyptus plantation trees using a resistance drilling technique

    Science.gov (United States)

    José Tarcísio da Silva Oliveira; Xiping Wang; Graziela Baptista Vidaurre

    2017-01-01

    The resistance drilling technique has been in focus for assessing the specific gravity (SG) of young Eucalyptus trees from plantations for pulpwood production. Namely, the data of 50 34-month-old and 50 62-monthold trees from Eucalyptus grandis × Eucalyptus urophylla clonal plantations was evaluated, while...

  20. Specification Techniques for Multi-Modal Dialogues in the U-Wish Project

    NARCIS (Netherlands)

    Nijholt, A.; Dijk, van E.M.A.G.; Donk, O.; Sanchez, B.; Nada, N.; Rashid, A.; Arndt, T.; Sanchez, M.

    2000-01-01

    In this paper we describe the development of a specification technique for specifying interactive web-based services. We wanted to design a language that can be a means of communication between designers and developers of interactive services, that makes it easier to develop web-based services fitte

  1. Specification Techniques for Multi-Modal Dialogues in the U-Wish Project

    NARCIS (Netherlands)

    Nijholt, Antinus; Donk, O.A.; van Dijk, Elisabeth M.A.G.; Donk, O.; Sanchez, B.; Nada, N.; Rashid, A.; Arndt, T.; Sanchez, M.

    2000-01-01

    In this paper we describe the development of a specification technique for specifying interactive web-based services. We wanted to design a language that can be a means of communication between designers and developers of interactive services, that makes it easier to develop web-based services

  2. Application Protocol, Initial Graphics Exchange Specification (IGES), Layered Electrical Product

    Energy Technology Data Exchange (ETDEWEB)

    O`Connell, L.J. [ed.

    1994-12-01

    An application protocol is an information systems engineering view of a specific product The view represents an agreement on the generic activities needed to design and fabricate the product the agreement on the information needed to support those activities, and the specific constructs of a product data standard for use in transferring some or all of the information required. This application protocol describes the data for electrical and electronic products in terms of a product description standard called the Initial Graphics Exchange Specification (IGES). More specifically, the Layered Electrical Product IGES Application Protocol (AP) specifies the mechanisms for defining and exchanging computer-models and their associated data for those products which have been designed in two dimensional geometry so as to be produced as a series of layers in IGES format The AP defines the appropriateness of the data items for describing the geometry of the various parts of a product (shape and location), the connectivity, and the processing and material characteristics. Excluded is the behavioral requirements which the product was intended to satisfy, except as those requirements have been recorded as design rules or product testing requirements.

  3. Compound-specific radiocarbon analysis - Analytical challenges and applications

    Energy Technology Data Exchange (ETDEWEB)

    Mollenhauer, G; Rethemeyer, J [Alfred-Wegener Institute for Polar and Marine Research Am Handelshafen 12, 27570 Bremerhaven (Germany)], E-mail: Gesine.Mollenhauer@awi.de

    2009-01-01

    Within the last decades, techniques have become available that allow measurement of isotopic compositions of individual organic compounds (compound-specific isotope measurements). Most often the carbon isotopic composition of these compounds is studied, including stable carbon ({delta}{sup 13}C) and radiocarbon ({delta}{sup 14}C) measurements. While compound-specific stable carbon isotope measurements are fairly simple, and well-established techniques are widely available, radiocarbon analysis of specific organic compounds is a more challenging method. Analytical challenges include difficulty obtaining adequate quantities of sample, tedious and complicated laboratory separations, the lack of authentic standards for measuring realistic processing blanks, and large uncertainties in values of {delta}{sup 14}C at small sample sizes. The challenges associated with sample preparation for compound-specific {delta}{sup 14}C measurements will be discussed in this contribution. Several years of compound-specific radiocarbon analysis have revealed that in most natural samples, purified organic compounds consist of heterogeneous mixtures of the same compound. These mixtures could derive from multiple sources, each having a different initial reservoir age but mixed in the same terminal reservoir, from a single source but mixed after deposition, or from a prokaryotic organism using variable carbon sources including mobilization of ancient carbon. These processes not only represent challenges to the interpretation of compound-specific radiocarbon data, but provide unique tools for the understanding of biogeochemical and sedimentological processes influencing the preserved organic geochemical records in marine sediments. We will discuss some examples where compound-specific radiocarbon analysis has provided new insights for the understanding of carbon source utilization and carbon cycling.

  4. Application of Artificial Intelligence Techniques in Unmanned Aerial Vehicle Flight

    Science.gov (United States)

    Bauer, Frank H. (Technical Monitor); Dufrene, Warren R., Jr.

    2003-01-01

    This paper describes the development of an application of Artificial Intelligence for Unmanned Aerial Vehicle (UAV) control. The project was done as part of the requirements for a class in Artificial Intelligence (AI) at Nova southeastern University and as an adjunct to a project at NASA Goddard Space Flight Center's Wallops Flight Facility for a resilient, robust, and intelligent UAV flight control system. A method is outlined which allows a base level application for applying an AI method, Fuzzy Logic, to aspects of Control Logic for UAV flight. One element of UAV flight, automated altitude hold, has been implemented and preliminary results displayed. A low cost approach was taken using freeware, gnu, software, and demo programs. The focus of this research has been to outline some of the AI techniques used for UAV flight control and discuss some of the tools used to apply AI techniques. The intent is to succeed with the implementation of applying AI techniques to actually control different aspects of the flight of an UAV.

  5. Research and Application of MEMS technique tat BSFF

    Institute of Scientific and Technical Information of China (English)

    YiFu-ting; PENGLigang-qiang; ZHANGJu-fang; HANYong; XIANDing-chang

    2001-01-01

    LIGA technique has been developed since 1993 at BSRF,including the fabrication of LIGA mask, deep X-ray Lithography,electroplating,the pouring molding and the applications in some fields.The LIGA mask with gold absorbing structures of 20μm thick ness and 5μm width and Kapton membrane of around 5μm thicness has been successfull fabricated and applied to the deep X-ray lithography with the PMMA structure of 1mm thickness or obove.the beamline form a wiggler is used for the deep X-ray lithography of LIGA statiion and is open to othe institutes researching the deep X-ray lithography.The normal process of LIGA technique with the exception of molding has been established with the PMMA structures of 500μm thickness at BSRF.The largest aspect ratio of PMMA structrues can reach about 50 with the height of 500μm and the lateral siae of 10μm. The nickel and copper structures with the theickness of 0.5mm and 1mm have been made by using the electroplating technique.The SU8 as a resist material of deep etch lithography with UV light is also developed in the fabrication of LIGA mask and some devices at BSRF.Electromagnetic stepping micro motor,haet exchange,accelerator,structures used in the EDM(electro discharge machinging) are being developed for the future applications.

  6. On the suitability of SIFT technique to deal with image modifications specific to confocal scanning laser microscopy.

    Science.gov (United States)

    Stanciu, Stefan G; Hristu, Radu; Boriga, Radu; Stanciu, George A

    2010-10-01

    Computer vision tasks such as recognition and classification of objects and structures or image registration and retrieval can provide significant information when applied to microscopy images. Recently developed techniques for the detection and description of local features make the extraction and description of local image features that are invariant to various changes possible. The invariance and robustness of feature detection and description techniques play a key role in the design and implementation of object recognition, image registration, or image mosaicing applications. The scale-invariant feature transform (SIFT) technique is a widely used method for the detection, description, and matching of image features. In this article we present the results of our experiments regarding the repeatability of SIFT features, and to the precision of the SIFT feature matching, under image modifications specific to confocal scanning laser microscopy (CSLM). We have analyzed the behavior of SIFT while changing the pinhole aperture, photomultiplier gain, laser beam power, and electronic zoom. Our experiments, conducted on CSLM images, show that the SIFT technique is able to match detected key points between images acquired at different values of the acquisition parameters with good precision and represents a consistent tool for computer vision applications in CSLM.

  7. Scheduling Semiconductor Multihead Testers Using Metaheuristic Techniques Embedded with Lot-Specific and Configuration-Specific Information

    Directory of Open Access Journals (Sweden)

    Yi-Feng Hung

    2013-01-01

    Full Text Available In the semiconductor back-end manufacturing, the device test central processing unit (CPU is most costly and is typically the bottleneck machine at the test plant. A multihead tester contains a CPU and several test heads, each of which can be connected to a handler that processes one lot of the same device. The residence time of a lot is closely related to the product mix on test heads, which increases the complexity of this problem. It is critical for the test scheduling problem to reduce CPU's idle time and to increase tester utilization. In this paper, a multihead tester scheduling problem is formulated as an identical parallel machine scheduling problem with the objective of minimizing makespan. A heuristic grouping method is developed to obtain a good initial solution in a short time. Three metaheuristic techniques, using lot-specific and configuration-specific information, are proposed to receive a near-optimum and are compared to traditional approaches. Computational experiments show that a tabu search with lot-specific information outperforms all other competing approaches.

  8. Optimizing calibration intervals for specific applications to reduce maintenance costs

    Energy Technology Data Exchange (ETDEWEB)

    Collier, Steve; Holland, Jack [Servomex Group, Crowborough (United Kingdom)

    2009-11-01

    The introduction of the Servomex MultiExact 5400 analyzer has presented an opportunity to review the cost of ownership and how improvements to an analyzer's performance may be used to reduce this. Until now, gas analyzer manufacturers have taken a conservative approach to calibration intervals based on site practices and experience covering a wide range of applications. However, if specific applications are considered, then there is an opportunity to reduce costs by increasing calibration intervals. This paper demonstrates how maintenance costs may be reduced by increasing calibration intervals for those gas analyzers used for monitoring Air Separation Units (ASUs) without detracting from their performance.(author)

  9. Application of Fascial Manipulation technique in chronic shoulder pain--anatomical basis and clinical implications.

    Science.gov (United States)

    Day, Julie Ann; Stecco, Carla; Stecco, Antonio

    2009-04-01

    Classical anatomy still relegates muscular fascia to a role of contention. Nonetheless, different hypotheses concerning the function of this resilient tissue have led to the formulation of numerous soft tissue techniques for the treatment of musculoskeletal pain. This paper presents a pilot study concerning the application of one such manual technique, Fascial Manipulation, in 28 subjects suffering from chronic posterior brachial pain. This method involves a deep kneading of muscular fascia at specific points, termed centres of coordination (cc) and centres of fusion (cf), along myofascial sequences, diagonals, and spirals. Visual Analogue Scale (VAS) measurement of pain administered prior to the first session, and after the third session was compared with a follow-up evaluation at 3 months. Results suggest that the application of Fascial Manipulation technique may be effective in reducing pain in chronic shoulder dysfunctions. The anatomical substratum of the myofascial continuity has been documented by dissections and the biomechanical model is discussed.

  10. Machine Learning Identification of Protein Properties Useful for Specific Applications

    KAUST Repository

    Khamis, Abdullah

    2016-03-31

    Proteins play critical roles in cellular processes of living organisms. It is therefore important to identify and characterize their key properties associated with their functions. Correlating protein’s structural, sequence and physicochemical properties of its amino acids (aa) with protein functions could identify some of the critical factors governing the specific functionality. We point out that not all functions of even well studied proteins are known. This, complemented by the huge increase in the number of newly discovered and predicted proteins, makes challenging the experimental characterization of the whole spectrum of possible protein functions for all proteins of interest. Consequently, the use of computational methods has become more attractive. Here we address two questions. The first one is how to use protein aa sequence and physicochemical properties to characterize a family of proteins. The second one focuses on how to use transcription factor (TF) protein’s domains to enhance accuracy of predicting TF DNA binding sites (TFBSs). To address the first question, we developed a novel method using computational representation of proteins based on characteristics of different protein regions (N-terminal, M-region and C-terminal) and combined these with the properties of protein aa sequences. We show that this description provides important biological insight about characterization of the protein functional groups. Using feature selection techniques, we identified key properties of proteins that allow for very accurate characterization of different protein families. We demonstrated efficiency of our method in application to a number of antimicrobial peptide families. To address the second question we developed another novel method that uses a combination of aa properties of DNA binding domains of TFs and their TFBS properties to develop machine learning models for predicting TFBSs. Feature selection is used to identify the most relevant characteristics

  11. Innovative SU-8 Lithography Techniques and Their Applications

    Directory of Open Access Journals (Sweden)

    Jeong Bong Lee

    2014-12-01

    Full Text Available SU-8 has been widely used in a variety of applications for creating structures in micro-scale as well as sub-micron scales for more than 15 years. One of the most common structures made of SU-8 is tall (up to millimeters high-aspect-ratio (up to 100:1 3D microstructure, which is far better than that made of any other photoresists. There has been a great deal of efforts in developing innovative unconventional lithography techniques to fully utilize the thick high aspect ratio nature of the SU-8 photoresist. Those unconventional lithography techniques include inclined ultraviolet (UV exposure, back-side UV exposure, drawing lithography, and moving-mask UV lithography. In addition, since SU-8 is a negative-tone photoresist, it has been a popular choice of material for multiple-photon interference lithography for the periodic structure in scales down to deep sub-microns such as photonic crystals. These innovative lithography techniques for SU-8 have led to a lot of unprecedented capabilities for creating unique micro- and nano-structures. This paper reviews such innovative lithography techniques developed in the past 15 years or so.

  12. Measuring and Assessing Application-Specific Technology Readiness

    Directory of Open Access Journals (Sweden)

    Antonino Ardilio

    2015-11-01

    Full Text Available Technology readiness is a crucial issue for decision-makers in technology-driven enterprises, determining whether the technology will or won’t be adopted for use in products or as a process technology. We know that, in some cases, lower technology readiness will be accepted by the users; these could be end-users, but, more often, it will be used in companies. The impact of a too early or too late adopted technology can be huge for companies and can even threaten market position or the existence of the company itself. Research institutes and technology developers, in particular application-oriented research organizations, might be also interested in which parameters or technology attributes should be improved or extended, according to the addressed application field, so that the technology fulfils the market-requested functions and a fast diffusion in the market can be achieved. Existing technology readiness models cover the various usages of the technology. In many cases, they assess the technology’s use in across different industries and application fields. However, the requirements in many fields are mostly different and very specific; thus, evaluation at such a high level can’t conclude whether the technology should be considered and adopted in the applications involved. This paper introduces an approach on how to determine and map the application-specific readiness of technology by decomposing both the application and the technology into its requested functions, as well as dynamically mapping the individual technology performance criteria. The applicability of this model will be demonstrated and discussed by a use case in the area of OLED-technology.

  13. Articular dysfunction patterns in patients with mechanical neck pain: a clinical algorithm to guide specific mobilization and manipulation techniques.

    Science.gov (United States)

    Dewitte, Vincent; Beernaert, Axel; Vanthillo, Bart; Barbe, Tom; Danneels, Lieven; Cagnie, Barbara

    2014-02-01

    In view of a didactical approach for teaching cervical mobilization and manipulation techniques to students as well as their use in daily practice, it is mandatory to acquire sound clinical reasoning to optimally apply advanced technical skills. The aim of this Masterclass is to present a clinical algorithm to guide (novice) therapists in their clinical reasoning to identify patients who are likely to respond to mobilization and/or manipulation. The presented clinical reasoning process is situated within the context of pain mechanisms and is narrowed to and applicable in patients with a dominant input pain mechanism. Based on key features in subjective and clinical examination, patients with mechanical nociceptive pain probably arising from articular structures can be categorized into specific articular dysfunction patterns. Pending on these patterns, specific mobilization and manipulation techniques are warranted. The proposed patterns are illustrated in 3 case studies. This clinical algorithm is the corollary of empirical expertise and is complemented by in-depth discussions and knowledge exchange with international colleagues. Consequently, it is intended that a carefully targeted approach contributes to an increase in specificity and safety in the use of cervical mobilizations and manipulation techniques as valuable adjuncts to other manual therapy modalities.

  14. Applications of synchrotron-based X-ray techniques in environmental science

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Synchrotron-based X-ray techniques have been widely applied to the fields of environmental science due to their element-specific and nondestructive properties and unique spectral and spatial resolution advantages.The techniques are capable of in situ investigating chemical speciation,microstructure and mapping of elements in question at the molecular or nanometer scale,and thus provide direct evidence for reaction mechanisms for various environmental processes.In this contribution,the applications of three types of the techniques commonly used in the fields of environmental research are reviewed,namely X-ray absorption spectroscopy (XAS),X-ray fluorescence (XRF) spectroscopy and scanning transmission X-ray microscopy (STXM).In particular,the recent advances of the techniques in China are elaborated,and a selection of the applied examples are provided in the field of environmental science.Finally,the perspectives of synchrotron-based X-ray techniques are discussed.With their great progress and wide application,the techniques have revolutionized our understanding of significant geo-and bio-chemical processes.It is anticipatable that synchrotron-based X-ray techniques will continue to play a significant role in the fields and significant advances will be obtained in decades ahead.

  15. Decomposition techniques in mathematical programming engineering and science applications

    CERN Document Server

    Conejo, Antonio J; Minguez, Roberto; Garcia-Bertrand, Raquel

    2006-01-01

    Optimization plainly dominates the design, planning, operation, and c- trol of engineering systems. This is a book on optimization that considers particular cases of optimization problems, those with a decomposable str- ture that can be advantageously exploited. Those decomposable optimization problems are ubiquitous in engineering and science applications. The book considers problems with both complicating constraints and complicating va- ables, and analyzes linear and nonlinear problems, with and without in- ger variables. The decomposition techniques analyzed include Dantzig-Wolfe, Benders, Lagrangian relaxation, Augmented Lagrangian decomposition, and others. Heuristic techniques are also considered. Additionally, a comprehensive sensitivity analysis for characterizing the solution of optimization problems is carried out. This material is particularly novel and of high practical interest. This book is built based on many clarifying, illustrative, and compu- tional examples, which facilitate the learning p...

  16. Different Applications of Rheological Techniques in Studies of Physical Gels

    DEFF Research Database (Denmark)

    Hvidt, Søren

    -forming biopolymers. Physical gels are also used in the paint industry to minimize sedimentation. Delayed and controlled drug release is of importance in the pharmaceutical industry, and one way to obtain this control is to hide active components in physical gels. Two excellent reviews cover many aspects...... of the elastic storage modulus, G’, and loss modulus, G”, as a function of e.g. frequency, temperature, or time. Two other techniques, which can be very useful for studies of gels, are creep and relaxation measurements. These techniques, which allow determinations of the compliance and the relaxation modulus...... importance in many applications. When a gel is deformed with increasing strain or strain amplitudes most gels eventually rupture. The yield stress denotes the maximum stress gels can withstand. Different ways of determining yield stress will be illustrated. Oscillatory measurements only allow determinations...

  17. Combined acquisition technique (CAT for neuroimaging of multiple sclerosis at low specific absorption rates (SAR.

    Directory of Open Access Journals (Sweden)

    Armin Biller

    Full Text Available PURPOSE: To compare a novel combined acquisition technique (CAT of turbo-spin-echo (TSE and echo-planar-imaging (EPI with conventional TSE. CAT reduces the electromagnetic energy load transmitted for spin excitation. This radiofrequency (RF burden is limited by the specific absorption rate (SAR for patient safety. SAR limits restrict high-field MRI applications, in particular. MATERIAL AND METHODS: The study was approved by the local Medical Ethics Committee. Written informed consent was obtained from all participants. T2- and PD-weighted brain images of n = 40 Multiple Sclerosis (MS patients were acquired by CAT and TSE at 3 Tesla. Lesions were recorded by two blinded, board-certificated neuroradiologists. Diagnostic equivalence of CAT and TSE to detect MS lesions was evaluated along with their SAR, sound pressure level (SPL and sensations of acoustic noise, heating, vibration and peripheral nerve stimulation. RESULTS: Every MS lesion revealed on TSE was detected by CAT according to both raters (Cohen's kappa of within-rater/across-CAT/TSE lesion detection κCAT = 1.00, at an inter-rater lesion detection agreement of κLES = 0.82. CAT reduced the SAR burden significantly compared to TSE (p<0.001. Mean SAR differences between TSE and CAT were 29.0 (± 5.7 % for the T2-contrast and 32.7 (± 21.9 % for the PD-contrast (expressed as percentages of the effective SAR limit of 3.2 W/kg for head examinations. Average SPL of CAT was no louder than during TSE. Sensations of CAT- vs. TSE-induced heating, noise and scanning vibrations did not differ. CONCLUSION: T2-/PD-CAT is diagnostically equivalent to TSE for MS lesion detection yet substantially reduces the RF exposure. Such SAR reduction facilitates high-field MRI applications at 3 Tesla or above and corresponding protocol standardizations but CAT can also be used to scan faster, at higher resolution or with more slices. According to our data, CAT is no more uncomfortable than TSE scanning.

  18. Beaming teaching application: recording techniques for spatial xylophone sound rendering

    DEFF Research Database (Denmark)

    Markovic, Milos; Madsen, Esben; Olesen, Søren Krarup;

    2012-01-01

    BEAMING is a telepresence research project aiming at providing a multimodal interaction between two or more participants located at distant locations. One of the BEAMING applications allows a distant teacher to give a xylophone playing lecture to the students. Therefore, rendering of the xylophone...... played at student's location is required at teacher's site. This paper presents a comparison of different recording techniques for a spatial xylophone sound rendering. Directivity pattern of the xylophone was measured and spatial properties of the sound field created by a xylophone as a distributed sound...

  19. Pulsed electrical discharges for medicine and biology techniques, processes, applications

    CERN Document Server

    Kolikov, Victor

    2015-01-01

    This book presents the application of pulsed electrical discharges in water and water dispersions of metal nanoparticles in medicine (surgery, dentistry, and oncology), biology, and ecology. The intensive electrical and shock waves represent a novel technique to destroy viruses and this way to  prepare anti-virus vaccines. The method of pulsed electrical discharges in water allows to decontaminate water from almost all known bacteria and spores of fungi being present in human beings. The nanoparticles used are not genotoxic and mutagenic. This book is useful for researchers and graduate students.

  20. Lab-on-a-chip techniques, circuits, and biomedical applications

    CERN Document Server

    Ghallab, Yehya H

    2010-01-01

    Here's a groundbreaking book that introduces and discusses the important aspects of lab-on-a-chip, including the practical techniques, circuits, microsystems, and key applications in the biomedical, biology, and life science fields. Moreover, this volume covers ongoing research in lab-on-a-chip integration and electric field imaging. Presented in a clear and logical manner, the book provides you with the fundamental underpinnings of lab-on-a-chip, presents practical results, and brings you up to date with state-of-the-art research in the field. This unique resource is supported with over 160 i

  1. Digital signal processing techniques and applications in radar image processing

    CERN Document Server

    Wang, Bu-Chin

    2008-01-01

    A self-contained approach to DSP techniques and applications in radar imagingThe processing of radar images, in general, consists of three major fields: Digital Signal Processing (DSP); antenna and radar operation; and algorithms used to process the radar images. This book brings together material from these different areas to allow readers to gain a thorough understanding of how radar images are processed.The book is divided into three main parts and covers:* DSP principles and signal characteristics in both analog and digital domains, advanced signal sampling, and

  2. Electromagnetic and Thermal Dosimetric Techniques in Humans and its Application

    Science.gov (United States)

    Hirata, Akimasa; Fujiwara, Osamu

    There has been increasing public concern about the adverse health effects of human exposure to radio frequency fields. Radio frequency fields are also used for medical application. This paper reviews electromagnetic and thermal computational dosimetric techniques, which has been developed by the authors. The feature of the thermal dosimetric method is that body core temperature can be computed reasonably unlike conventional method. This scheme is particularly useful for intense localized or whole-body electromagnetic wave exposure. Computational examples are shown to verify the effectiveness of the proposal.

  3. Optical and digital microscopic imaging techniques and applications in pathology.

    Science.gov (United States)

    Chen, Xiaodong; Zheng, Bin; Liu, Hong

    2011-01-01

    The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy to facilitate clinical screening and diagnosis. This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications of optical microscopes, electron microscopes, scanning tunnel microscopes, and fluorescence microscopes. The interface of microscopy with digital image acquisition methods is discussed. The recent developments and future perspectives of contemporary microscopic imaging techniques such as three-dimensional and in vivo imaging are analyzed for their clinical potentials.

  4. Application of digital image processing techniques to astronomical imagery, 1979

    Science.gov (United States)

    Lorre, J. J.

    1979-01-01

    Several areas of applications of image processing to astronomy were identified and discussed. These areas include: (1) deconvolution for atmospheric seeing compensation; a comparison between maximum entropy and conventional Wiener algorithms; (2) polarization in galaxies from photographic plates; (3) time changes in M87 and methods of displaying these changes; (4) comparing emission line images in planetary nebulae; and (5) log intensity, hue saturation intensity, and principal component color enhancements of M82. Examples are presented of these techniques applied to a variety of objects.

  5. Application of stereo photogrammetric techniques for measuring African Elephants

    Directory of Open Access Journals (Sweden)

    A. J Hall-Martin

    1979-01-01

    Full Text Available Measurements of shoulder height and back length of African elephants were obtained by means of stereo photogrammetric techniques. A pair of Zeiss UMK 10/1318 cameras, mounted on a steel frame on the back of a vehicle, were used to photograph the elephants in the Addo Elephant National Park, Republic of South Africa. Several modifications of normal photogrammetry procedure applicable to the field situation (eg. control points and the computation of results (eg. relative orientation are briefly mentioned. Six elephants were immobilised after being photographed and the measurements obtained from them agreed within a range of 1 cm-10 cm with the photogrammetric measurements.

  6. Study of multilayers by PIXE technique. Application to paintings

    Science.gov (United States)

    Brissaud, Ivan; Lagarde, Gérard; Midy, Pierre

    1996-08-01

    In this article we propose the application of a new algorithm to determine the concentration profile of colour pigments in painting. This is performed by PIXE technique at different proton energies. The algorithm is based on the singular value decomposition of the matrix obtained by discretization of the integral equation for the concentration profile. To check this method, many paint multilayers of acrylic colours were prepared. First results obtained from different experiments at the AGLAE accelerator in the Palais du Louvre at Paris are presented: the nature and the thickness of each colour layer were determined with a good agreement. The analysis of easel paintings is in progress.

  7. Techniques, Applications and Challenging Issue in Text Mining

    Directory of Open Access Journals (Sweden)

    Shaidah Jusoh

    2012-11-01

    Full Text Available Text mining is a very exciting research area as it tries to discover knowledge from unstructured texts. These texts can be found on a desktop, intranets and the internet. The aim of this paper is to give an overview of text mining in the contexts of its techniques, application domains and the most challenging issue. The focus is given on fundamentals methods of text mining which include natural language possessing and information extraction. This paper also gives a short review on domains which have employed text mining. The challenging issue in text mining which is caused by the complexity in a natural language is also addressed in this paper.

  8. Digital holography and wavefront sensing principles, techniques and applications

    CERN Document Server

    Schnars, Ulf; Watson, John; Jüptner, Werner

    2015-01-01

    This book presents a self-contained treatment of the principles and major applications of digital hologram recording and numerical reconstruction (Digital Holography). This second edition has been significantly revised and enlarged. The authors have extended the chapter on Digital Holographic Microscopy to incorporate new sections on particle sizing, particle image velocimetry and underwater holography. A new chapter now deals comprehensively and extensively with computational wave field sensing. These techniques represent a fascinating alternative to standard interferometry and Digital Holography. They enable wave field sensing without the requirement of a particular reference wave, thus allowing the use of low brilliance light sources and even liquid-crystal displays (LCD) for interferometric applications.              

  9. An Acoustic Communication Technique of Nanorobot Swarms for Nanomedicine Applications.

    Science.gov (United States)

    Loscrí, Valeria; Vegni, Anna Maria

    2015-09-01

    In this contribution, we present a communication paradigm among nanodevices, based on acoustic vibrations for medical applications. We consider a swarm of nanorobots able to communicate in a distributed and decentralized fashion, propelled in a biological environment (i.e., the human brain). Each nanorobot is intended to i) recognize a cancer cell, ii) destroy it, and then iii) forward information about the presence of cancer formation to other nanorobots, through acoustic signals. The choice of acoustic waves as communication mean is related to the application context, where it is not advisable either to use indiscriminate chemical substances or electromagnetic waves. The effectiveness of the proposed approach is assessed in terms of achievement of the objective (i.e., to destroy the majority of tumor cells), and the velocity of detection and destruction of cancer cells, through a comparison with other related techniques.

  10. Application of adaptive antenna techniques to future commercial satellite communication

    Science.gov (United States)

    Ersoy, L.; Lee, E. A.; Matthews, E. W.

    1987-01-01

    The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

  11. Target Detection: Remote Sensing Techniques for Defence Applications

    Directory of Open Access Journals (Sweden)

    B. B. Chaudhuri

    1995-10-01

    Full Text Available The tremendous development in remote sensing technology in the recent past has opened up new challenges in defence applications. On important area of such applications is in target detection. This paper describes both classical and newly developed approaches to detect the targets by using remotely-sensed digital images. The classical approach includes statistical classification methods and image processing techniques. The new approach deals with a relatively new sensor technology, namely, synthetic aperture radar (SAR systems and fast developing tools, like neural networks and multisource data integration for analysis and interpretation. With SAR images, it is possible to detect targets or features of a target that is otherwise not possible. Neural networks and multisource data integration tools also have a great potential in analysing and interpreting remote sensing data for target detection.

  12. Analysis of Formal Methods for Specification of E-Commerce Applications

    Directory of Open Access Journals (Sweden)

    Sadiq Ali Khan

    2016-01-01

    Full Text Available E-commerce based application characteristics portray elevated dynamics while incorporating decentralized nature. Extreme emphasis influencing structural design plus implementation, positions such applications highly appreciated. Significant research articles reveal that, applying formal methods addressing challenges incumbent with E-commerce based applications, contribute towards reliability and robustness obliging the system. Anticipating and designing sturdy e-process and concurrent implementation, allows application behavior extra strength against errors, frauds and hacking, minimizing program faults during application operations. Programmers find extreme difficulty guaranteeing correct processing under all circumstances, however, not impossible. Concealed flaws and errors, triggered only under unexpected and unanticipated scenarios, pilot subtle mistakes and appalling failures. Code authors utilize various formal methods for reducing these flaws. Mentioning prominent methods would include, ASM (Abstract State Machines, B-Method, z-Language, UML (Unified Modelling Language etc. This paper primarily focuses different formal methods applied while deliberating specification and verification techniques for cost effective.

  13. Application of Structured Light System Technique for Authentication of Wooden Panel Paintings

    Directory of Open Access Journals (Sweden)

    Fernando Buchón-Moragues

    2016-06-01

    Full Text Available This paper presents a new application of photogrammetric techniques for protecting cultural heritage. The accuracy of the method and the fact that it can be used to carry out different tests without contact between the sample and the instruments can make this technique very useful for authenticating and cataloging artworks. The application focuses on the field of pictorial artworks, and wooden panel paintings in particular. In these works, the orography formed by the brushstrokes can be easily digitalized using a photogrammetric technique, called Structured Light System, with submillimeter accuracy. Thus, some of the physical characteristics of the brushstrokes, like minimum and maximum heights or slopes become a fingerprint of the painting. We explain in detail the general principles of the Structured Light System Technique and the specific characteristics of the commercial set-up used in this work. Some experiments are carried out on a sample painted by us to check the accuracy limits of the technique and to propose some tests that can help to stablish a methodology for authentication purposes. Finally, some preliminary results obtained on a real pictorial artwork are presented, providing geometrical information of its metric features as an example of the possibilities of this application.

  14. Application of Structured Light System Technique for Authentication of Wooden Panel Paintings

    Science.gov (United States)

    Buchón-Moragues, Fernando; Bravo, José María; Ferri, Marcelino; Redondo, Javier; Sánchez-Pérez, Juan Vicente

    2016-01-01

    This paper presents a new application of photogrammetric techniques for protecting cultural heritage. The accuracy of the method and the fact that it can be used to carry out different tests without contact between the sample and the instruments can make this technique very useful for authenticating and cataloging artworks. The application focuses on the field of pictorial artworks, and wooden panel paintings in particular. In these works, the orography formed by the brushstrokes can be easily digitalized using a photogrammetric technique, called Structured Light System, with submillimeter accuracy. Thus, some of the physical characteristics of the brushstrokes, like minimum and maximum heights or slopes become a fingerprint of the painting. We explain in detail the general principles of the Structured Light System Technique and the specific characteristics of the commercial set-up used in this work. Some experiments are carried out on a sample painted by us to check the accuracy limits of the technique and to propose some tests that can help to stablish a methodology for authentication purposes. Finally, some preliminary results obtained on a real pictorial artwork are presented, providing geometrical information of its metric features as an example of the possibilities of this application. PMID:27314353

  15. Application of Structured Light System Technique for Authentication of Wooden Panel Paintings.

    Science.gov (United States)

    Buchón-Moragues, Fernando; Bravo, José María; Ferri, Marcelino; Redondo, Javier; Sánchez-Pérez, Juan Vicente

    2016-06-14

    This paper presents a new application of photogrammetric techniques for protecting cultural heritage. The accuracy of the method and the fact that it can be used to carry out different tests without contact between the sample and the instruments can make this technique very useful for authenticating and cataloging artworks. The application focuses on the field of pictorial artworks, and wooden panel paintings in particular. In these works, the orography formed by the brushstrokes can be easily digitalized using a photogrammetric technique, called Structured Light System, with submillimeter accuracy. Thus, some of the physical characteristics of the brushstrokes, like minimum and maximum heights or slopes become a fingerprint of the painting. We explain in detail the general principles of the Structured Light System Technique and the specific characteristics of the commercial set-up used in this work. Some experiments are carried out on a sample painted by us to check the accuracy limits of the technique and to propose some tests that can help to stablish a methodology for authentication purposes. Finally, some preliminary results obtained on a real pictorial artwork are presented, providing geometrical information of its metric features as an example of the possibilities of this application.

  16. Application of borehole acoustic logging techniques in engineering geology

    Energy Technology Data Exchange (ETDEWEB)

    McCann, D.M.; McCann, C.

    1977-01-01

    Most site investigations for civil engineering developments use a large number of boreholes to obtain geological information and to collect samples for geotechnical measurements in the laboratory. However, samples taken from boreholes are often highly disturbed and even the most carefully taken sample is subjected to a relief in the overburden pressure as it is removed from the ground. There has, thus, been a growing interest in the use of boreholes for in-situ testing methods in order to optimize the amount of useful information that can be obtained from a borehole study. In this paper, the use of borehole geophysical logging technique in engineering geological applications is reviewed with special emphasis on acoustic methods. The study also includes the associated methods of surface to borehole and borehole to borehole measurements, which have an equally important role to play in the civil engineering field. The results of several case histories are presented and these demonstrate the practical application of borehole geophysical techniques. Of particular interest in the study is an examination of (a) the determination of the dynamic elastic moduli in a rock mass, (b) the variation in lithology with depth and associated changes in the engineering properties and (c) the continuity of strata between boreholes.

  17. An Efficient Application Specific Memory Storage and ASIP Behavior Optimization in Embedded System

    Directory of Open Access Journals (Sweden)

    Ravi Khatwal

    2016-07-01

    Full Text Available Low power embedded system requires effective memory design system which improves the system performance with the help of memory implementation techniques. Application specific data allocation design pattern implements the memory storage area and internal cell design techniques implements data transition speeds. Embedded cache design is implemented with simulator and scheduling approaches which can reduce the cache miss behavior and improve the cache hit quantities. Cache hit optimization, delay reduction and latency prediction techniques are effective for ASIP design. The design functionality is simply specifying the tradeoff among various design metrics like performance, power, size, cost and flexibility. ASIP behavior and memory storage area optimized for low power embedded system and implements cycle time with effective scheduling techniques which implements the system performance with low power consumption.

  18. Development of optical techniques for chemical engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Lamadie, F.; Charton, S.; Langlard, M. de; Ouattara, M.; Sentis, M. [CEA, Centre de Marcoule, DEN,DTEC,SGCS, F-30207 Marcoule (France)

    2016-07-01

    The design of separation processes for nuclear spend fuel treatment, dedicated to either research studies or industrial applications, is currently based on a phenomenological approach, relying on Computational Fluid Dynamics, and complemented by validation tests performed at small-scale. Indeed, most of the steps of the Purex process involve multiphasic flows (dissolution, leaching, liquid-liquid extraction, precipitation, filtration, etc.). Therefore an accurate knowledge of the dispersed phase properties is required in order to assess their coupling with the flow features, to predict the process performance and efficiency and to achieve size reduction or extrapolation. Hence, the measurements of particulate flows properties, and especially the particles (or drops or bubbles) size distribution, concentration (i.e. hold-up) and velocity has become a growing issue. Relevant techniques for measuring these flow properties are multiple, from the high-speed video acquisition coupled to image processing to the laser-induced fluorescence, including the particle imaging velocimetry or interferometric techniques (digital in-line holography, rainbow refractometry, etc.). In this communication, different techniques developed at CEA Marcoule for the characterization of multiphase flows, will be introduced. The strong interaction with computational fluid dynamics, in the scope of a multi-scale approach, will be discussed through typical results of gas-liquid, liquid-liquid and solid-liquid flows possibly encountered in nuclear fuel reprocessing process. (authors)

  19. Evaluation of the compound-specific stable isotope (CSSI) technique in an agricultural watershed in Manitoba, Canada

    Science.gov (United States)

    Reiffarth, Dominic; Petticrew, Ellen; Lobb, David

    2015-04-01

    Tracing the movement of sediment within a watershed allows for the determination of sediment sources and sinks. By tracing and apportioning sources contributing to a sink, environmental concerns such as erosion and the transport of sediment-bound pollutants may be addressed. Common tools used in tracing have included the use of soil geochemistry, fallout radionuclides (FRNs), color and magnetism. Recently, the use of compound-specific stable isotopes (CSSIs) has been investigated as a potential tracing tool. The application, reliability and analytical procedures for CSSIs in soil and sediment tracing are still undergoing evaluation in order to determine the robustness, cost and reliability of the method. The CSSI technique adds to the current toolbox of methods by providing a land use-specific tracer i.e. organic compounds (fatty acids, FAs) that are of plant origin. The FAs are analyzed for the 13C:12C ratios (the stable isotopes of carbon) for each specific type of FA uniquely of plant origin. An investigation of FA biomarkers and their applicability to tracing using the CSSI technique was undertaken in the South Tobacco Creek Watershed (STCW, 75 km2), Manitoba, Canada, over a two year period (2012-2013) throughout the growing season. Transects and sampling points were determined so as to capture temporal and spatial variability within the watershed. The vegetation i.e. crops were planted so as to be separated topographically, thereby isolating field hydrology and mixing of crop FA signals, with inter-annual crop rotation. The data are to be analyzed to determine the spatial and temporal influences of the CSSI signal and the potential for recognizing a representative field sample. Points further downstream of the cropped fields were also sampled to determine the ability to apportion sediments and detect influences on the CSSI signal after transport. Results of the sampling, in both the near and far field, will allow the evaluation of this technique as a robust

  20. Development of a PCR technique specific for Demodex injai in biological specimens.

    Science.gov (United States)

    Sastre, N; Ravera, I; Ferreira, D; Altet, L; Sánchez, A; Bardagí, M; Francino, O; Ferrer, L

    2013-09-01

    The identification of Demodex injai as a second Demodex species of dog opened new questions and challenges in the understanding on the Demodex-host relationships. In this paper, we describe the development of a conventional PCR technique based on published genome sequences of D. injai from GenBank that specifically detects DNA from D. injai. This technique amplifies a 238-bp fragment corresponding to a region of the mitochondrial 16S rDNA of D. injai. The PCR was positive in DNA samples obtained from mites identified morphologically as D. injai, which served as positive controls, as well as in samples from three cases of demodicosis associated with proliferation of mites identified as D. injai. Furthermore, the PCR was positive in 2 out of 19 healthy dogs. Samples of Demodex canis and Demodex folliculorum were consistently negative. Skin samples from seven dogs with generalized demodicosis caused by D. canis were all negative in the D. injai-specific PCR, demonstrating that in generalized canine demodicosis, mite proliferation is species-specific. This technique can be a useful tool in the diagnosis and in epidemiologic and pathogenic studies.

  1. Techniques for endoscopic and non-endoscopic intracorporeal laser applications.

    Science.gov (United States)

    Fuchs, B; Philipp, C; Engel-Murke, F; Shaltout, J; Berlien, H P

    1993-08-01

    This article deals with various designs of CO2 and Nd:YAG lasers currently used in surgery. It is discussed how their wavelength and beampath characteristics can be utilized in either the contact or the non-contact method to achieve specific clinical aims. These may concern endoscopic procedures, e.g. palliative tumour destruction or haemangioma or cystic membrane coagulation, or non-endoscopic procedures, as exemplified by two case reports on treatment for a congenital vascular disorder and varicosis, respectively. As there is a certain overlap of laser and high-frequency applications, their respective advantages and drawbacks are compared in detail. The main safety concern in HF surgery is that of errant currents in the patient, whereas in laser applications the main hazard is to the operators' eyes. This hazard can be safely eliminated.

  2. Modular Ontology Techniques and their Applications in the Biomedical Domain.

    Science.gov (United States)

    Pathak, Jyotishman; Johnson, Thomas M; Chute, Christopher G

    2008-08-05

    In the past several years, various ontologies and terminologies such as the Gene Ontology have been developed to enable interoperability across multiple diverse medical information systems. They provide a standard way of representing terms and concepts thereby supporting easy transmission and interpretation of data for various applications. However, with their growing utilization, not only has the number of available ontologies increased considerably, but they are also becoming larger and more complex to manage. Toward this end, a growing body of work is emerging in the area of modular ontologies where the emphasis is on either extracting and managing "modules" of an ontology relevant to a particular application scenario (ontology decomposition) or developing them independently and integrating into a larger ontology (ontology composition). In this paper, we investigate state-of-the-art approaches in modular ontologies focusing on techniques that are based on rigorous logical formalisms as well as well-studied graph theories. We analyze and compare how such approaches can be leveraged in developing tools and applications in the biomedical domain. We conclude by highlighting some of the limitations of the modular ontology formalisms and put forward additional requirements to steer their future development.

  3. EPR spectroscopy and its use in planta - a promising technique to disentangle the origin of specific ROS

    Directory of Open Access Journals (Sweden)

    Anja eSteffen-Heins

    2015-03-01

    Full Text Available While it is widely accepted that reactive oxygen species (ROS are common players in developmental processes and a large number of adaptations to abiotic and biotic stresses in plants, we still do not know a lot about ROS level control at cellular or organelle level. One major problem that makes ROS hard to quantify and even to identify is their short lifetime. A promising technique that helps to understand ROS level control in planta is the electron paramagnetic resonance (EPR spectroscopy. Application of the spin trapping method and the spin probe technique by this advanced method enables the quantification and identification of specific ROS in different plant tissues, cells or organelles or under different conditions. This mini review summarizes the knowledge using EPR spectroscopy as a method for ROS detection in plants under different stress conditions or during development. This technique allows disentangling the origin of specific ROS and transient alteration in ROS levels that occur by changes in ROS production and scavenging.

  4. Highly integrated application specific MMICs for active phased array radar applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den

    1999-01-01

    Application specific MMIC solutions for active array radar, developed at TNO-FEL, are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart

  5. Highly Integrated Application Specific MMICS for Active Phased Array Radar Applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den

    2000-01-01

    Application specific MMIC solutions for active array radar, developed at TNO-FEL. are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart

  6. 37 CFR 1.163 - Specification and arrangement of application elements in a plant application.

    Science.gov (United States)

    2010-07-01

    ... development. (4) Latin name of the genus and species of the plant claimed. (5) Variety denomination. (6... of application elements in a plant application. 1.163 Section 1.163 Patents, Trademarks, and... PATENT CASES National Processing Provisions Plant Patents § 1.163 Specification and arrangement of...

  7. Highly Integrated Application Specific MMICS for Active Phased Array Radar Applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den

    2000-01-01

    Application specific MMIC solutions for active array radar, developed at TNO-FEL. are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart s

  8. Highly integrated application specific MMICs for active phased array radar applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den

    1999-01-01

    Application specific MMIC solutions for active array radar, developed at TNO-FEL, are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart s

  9. Applications of nuclear techniques relevant for civil security

    Science.gov (United States)

    Valkovi, Vlado

    2006-05-01

    The list of materials which are subject to inspection with the aim of reducing the acts of terrorism includes explosives, narcotics, chemical weapons, hazardous chemicals and radioactive materials. To this we should add also illicit trafficking with human beings. The risk of nuclear terrorism carried out by sub-national groups is considered not only in construction and/or use of nuclear device, but also in possible radioactive contamination of large urban areas. Modern personnel, parcel, vehicle and cargo inspection systems are non-invasive imaging techniques based on the use of nuclear analytical techniques. The inspection systems use penetrating radiations: hard x-rays (300 keV or more) or gamma-rays from radioactive sources (137Cs and 60Co with energies from 600 to 1300 keV) that produce a high resolution radiograph of the load. Unfortunately, this information is ''non-specific'' in that it gives no information on the nature of objects that do not match the travel documents and are not recognized by a visual analysis of the radiographic picture. Moreover, there are regions of the container where x and gamma-ray systems are ''blind'' due to the high average atomic number of the objects irradiated that appear as black spots in the radiographic image. Contrary to that is the use of neutrons; as results of the bombardment, nuclear reactions occur and a variety of nuclear particles, gamma and x-ray radiation is emitted, specific for each element in the bombarded material. The problem of material (explosive, drugs, chemicals, etc.) identification can be reduced to the problem of measuring elemental concentrations. Neutron scanning technology offers capabilities far beyond those of conventional inspection systems. The unique automatic, material specific detection of terrorist threats can significantly increase the security at ports, border-crossing stations, airports, and even within the domestic transportation infrastructure of potential urban targets as well as

  10. Applications of nuclear techniques relevant for civil security

    Energy Technology Data Exchange (ETDEWEB)

    Valkovi, Vlado [Institute Ruder Boskovi, Zagreb (Croatia)

    2006-05-15

    The list of materials which are subject to inspection with the aim of reducing the acts of terrorism includes explosives, narcotics, chemical weapons, hazardous chemicals and radioactive materials. To this we should add also illicit trafficking with human beings. The risk of nuclear terrorism carried out by sub-national groups is considered not only in construction and/or use of nuclear device, but also in possible radioactive contamination of large urban areas. Modern personnel, parcel, vehicle and cargo inspection systems are non-invasive imaging techniques based on the use of nuclear analytical techniques. The inspection systems use penetrating radiations: hard x-rays (300 keV or more) or gamma-rays from radioactive sources ({sup 137}Cs and {sup 60}Co with energies from 600 to 1300 keV) that produce a high resolution radiograph of the load. Unfortunately, this information is 'non-specific' in that it gives no information on the nature of objects that do not match the travel documents and are not recognized by a visual analysis of the radiographic picture. Moreover, there are regions of the container where x and gamma-ray systems are 'blind' due to the high average atomic number of the objects irradiated that appear as black spots in the radiographic image. Contrary to that is the use of neutrons; as results of the bombardment, nuclear reactions occur and a variety of nuclear particles, gamma and x-ray radiation is emitted, specific for each element in the bombarded material. The problem of material (explosive, drugs, chemicals, etc.) identification can be reduced to the problem of measuring elemental concentrations. Neutron scanning technology offers capabilities far beyond those of conventional inspection systems. The unique automatic, material specific detection of terrorist threats can significantly increase the security at ports, border-crossing stations, airports, and even within the domestic transportation infrastructure of potential

  11. Application of lean manufacturing techniques in the Emergency Department.

    Science.gov (United States)

    Dickson, Eric W; Singh, Sabi; Cheung, Dickson S; Wyatt, Christopher C; Nugent, Andrew S

    2009-08-01

    "Lean" is a set of principles and techniques that drive organizations to continually add value to the product they deliver by enhancing process steps that are necessary, relevant, and valuable while eliminating those that fail to add value. Lean has been used in manufacturing for decades and has been associated with enhanced product quality and overall corporate success. To evaluate whether the adoption of Lean principles by an Emergency Department (ED) improves the value of emergency care delivered. Beginning in December 2005, we implemented a variety of Lean techniques in an effort to enhance patient and staff satisfaction. The implementation followed a six-step process of Lean education, ED observation, patient flow analysis, process redesign, new process testing, and full implementation. Process redesign focused on generating improvement ideas from frontline workers across all departmental units. Value-based and operational outcome measures, including patient satisfaction, expense per patient, ED length of stay (LOS), and patient volume were compared for calendar year 2005 (pre-Lean) and periodically after 2006 (post-Lean). Patient visits increased by 9.23% in 2006. Despite this increase, LOS decreased slightly and patient satisfaction increased significantly without raising the inflation adjusted cost per patient. Lean improved the value of the care we delivered to our patients. Generating and instituting ideas from our frontline providers have been the key to the success of our Lean program. Although Lean represents a fundamental change in the way we think of delivering care, the specific process changes we employed tended to be simple, small procedure modifications specific to our unique people, process, and place. We, therefore, believe that institutions or departments aspiring to adopt Lean should focus on the core principles of Lean rather than on emulating specific process changes made at other institutions.

  12. Application Specific Performance Technology for Productive Parallel Computing

    Energy Technology Data Exchange (ETDEWEB)

    Malony, Allen D. [Univ. of Oregon, Eugene, OR (United States); Shende, Sameer [Univ. of Oregon, Eugene, OR (United States)

    2008-09-30

    Our accomplishments over the last three years of the DOE project Application- Specific Performance Technology for Productive Parallel Computing (DOE Agreement: DE-FG02-05ER25680) are described below. The project will have met all of its objectives by the time of its completion at the end of September, 2008. Two extensive yearly progress reports were produced in in March 2006 and 2007 and were previously submitted to the DOE Office of Advanced Scientific Computing Research (OASCR). Following an overview of the objectives of the project, we summarize for each of the project areas the achievements in the first two years, and then describe in some more detail the project accomplishments this past year. At the end, we discuss the relationship of the proposed renewal application to the work done on the current project.

  13. Novel Designs for Application Specific MEMS Pressure Sensors

    DEFF Research Database (Denmark)

    Fragiacomo, Giulio; Reck, Kasper; Lorenzen, Lasse Vestergaard

    2010-01-01

    In the framework of developing innovative microfabricated pressure sensors, we present here three designs based on different readout principles, each one tailored for a specific application. A touch mode capacitive pressure sensor with high sensitivity (14 pF/bar), low temperature dependence...... and high capacitive output signal (more than 100 pF) is depicted. An optical pressure sensor intrinsically immune to electromagnetic interference, with large pressure range (0-350 bar) and a sensitivity of 1 pm/bar is presented. Finally, a resonating wireless pressure sensor power source free...

  14. Physics of nuclear radiations concepts, techniques and applications

    CERN Document Server

    Rangacharyulu, Chary

    2013-01-01

    Physics of Nuclear Radiations: Concepts, Techniques and Applications makes the physics of nuclear radiations accessible to students with a basic background in physics and mathematics. Rather than convince students one way or the other about the hazards of nuclear radiations, the text empowers them with tools to calculate and assess nuclear radiations and their impact. It discusses the meaning behind mathematical formulae as well as the areas in which the equations can be applied. After reviewing the physics preliminaries, the author addresses the growth and decay of nuclear radiations, the stability of nuclei or particles against radioactive transformations, and the behavior of heavy charged particles, electrons, photons, and neutrons. He then presents the nomenclature and physics reasoning of dosimetry, covers typical nuclear facilities (such as medical x-ray machines and particle accelerators), and describes the physics principles of diverse detectors. The book also discusses methods for measuring energy a...

  15. Applications of synchrotron radiation techniques to materials science 4

    Energy Technology Data Exchange (ETDEWEB)

    Mini, S.M. [ed.] [Northern Illinois Univ., DeKalb, IL (United States)]|[Argonne National Lab., IL (United States); Stock, S.R. [ed.] [Georgia Inst. of Tech., Atlanta, GA (United States); Perry, D.L. [ed.] [Lawrence Berkeley National Lab., CA (United States); Terminello, L.J. [ed.] [Lawrence Livermore National Lab., CA (United States)

    1998-12-31

    As more synchrotron facilities are constructed and go online both in the US and in other countries, even more applications of synchrotron radiation will be realized. Both basic and applied research possibilities are manifold, including studies of materials mentioned below and those that are yet to be discovered. Also, the combination of synchrotron-based spectroscopic techniques with ever increasing high-resolution microscopy allows researchers to study very small domains of materials in an attempt to understand their chemical and electronic properties. This is especially important in the areas of composites and other related materials involving material bonding interfaces. The topics covered in this symposium include surfaces, interfaces, electronic materials, metal oxides, solar cells, thin films, carbides, polymers, alloys, nanoparticles, and graphitic materials. Results reported at this symposium relate recent advances in X-ray absorption and scattering, imaging, tomography, microscopy, and topography methods.

  16. Study on application of optical clearing technique in skin diseases

    Science.gov (United States)

    Shan, Hao; Liang, Yanmei; Wang, Jingyi; Li, Yan

    2012-11-01

    So far, the study of the optical clearing is almost always about healthy tissue. However, the ultimate goal is to detect diseases for clinical application. Optical clearing on diseased skins is explored. The effect is evaluated by applying a combined liquid paraffin and glycerol mixed solution on several kinds of diseased skins in vitro. Scanning experiments from optical coherence tomography show that it has different effects among fibroma, pigmented nevus, and seborrheic keratosis. Based on the results, we conclude that different skin diseases have different compositions and structures, and their optical parameters and biological characteristics should be different, which implies that the optical clearing technique may have selectivity and may not be suitable for all kinds of skin diseases.

  17. The Application of Quantitative Fluorescence Techniques in China

    Institute of Scientific and Technical Information of China (English)

    Hu Yutao; Yang Haibo; Guo Qingxia

    2000-01-01

    The introduction of multi-methods of Geo-logging at wellsite has become the major measurement of oil & gas exploration. From the early stage of manually geo-logging to the modern mudlogging with new techonlogies of MWD, LWD and QFT etc. The new technologies have played very important roles in the exploring of oil & gas. Being one of the newest technology of mudlogging, QFT has been widely used in oilfield for about 3 years. When it is put in operation in some oilfields of China in 1997, its advantages in oil & gas detection at wellsite have been continuously recognized, especially in the detection of shows of light oil and condensed oil.Aset of powerful classification standard of resource rock oil bearing grades and the interpretation standards have been summarized by the application of the quantitative fluorescencelogging techniques (QFT) in Basins of China, together with gas-logging data, and other information got from the Geo-logging procedures at wellsite.

  18. Optical and Digital Microscopic Imaging Techniques and Applications in Pathology

    Directory of Open Access Journals (Sweden)

    Xiaodong Chen

    2011-01-01

    Full Text Available The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy to facilitate clinical screening and diagnosis. This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications of optical microscopes, electron microscopes, scanning tunnel microscopes, and fluorescence microscopes. The interface of microscopy with digital image acquisition methods is discussed. The recent developments and future perspectives of contemporary microscopic imaging techniques such as three-dimensional and in vivo imaging are analyzed for their clinical potentials.

  19. Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications

    Directory of Open Access Journals (Sweden)

    Anna Gilpin

    2017-01-01

    Full Text Available As the gap between donors and patients in need of an organ transplant continues to widen, research in regenerative medicine seeks to provide alternative strategies for treatment. One of the most promising techniques for tissue and organ regeneration is decellularization, in which the extracellular matrix (ECM is isolated from its native cells and genetic material in order to produce a natural scaffold. The ECM, which ideally retains its inherent structural, biochemical, and biomechanical cues, can then be recellularized to produce a functional tissue or organ. While decellularization can be accomplished using chemical and enzymatic, physical, or combinative methods, each strategy has both benefits and drawbacks. The focus of this review is to compare the advantages and disadvantages of these methods in terms of their ability to retain desired ECM characteristics for particular tissues and organs. Additionally, a few applications of constructs engineered using decellularized cell sheets, tissues, and whole organs are discussed.

  20. Nonlinear plasmonic imaging techniques and their biological applications

    Science.gov (United States)

    Deka, Gitanjal; Sun, Chi-Kuang; Fujita, Katsumasa; Chu, Shi-Wei

    2017-01-01

    Nonlinear optics, when combined with microscopy, is known to provide advantages including novel contrast, deep tissue observation, and minimal invasiveness. In addition, special nonlinearities, such as switch on/off and saturation, can enhance the spatial resolution below the diffraction limit, revolutionizing the field of optical microscopy. These nonlinear imaging techniques are extremely useful for biological studies on various scales from molecules to cells to tissues. Nevertheless, in most cases, nonlinear optical interaction requires strong illumination, typically at least gigawatts per square centimeter intensity. Such strong illumination can cause significant phototoxicity or even photodamage to fragile biological samples. Therefore, it is highly desirable to find mechanisms that allow the reduction of illumination intensity. Surface plasmon, which is the collective oscillation of electrons in metal under light excitation, is capable of significantly enhancing the local field around the metal nanostructures and thus boosting up the efficiency of nonlinear optical interactions of the surrounding materials or of the metal itself. In this mini-review, we discuss the recent progress of plasmonics in nonlinear optical microscopy with a special focus on biological applications. The advancement of nonlinear imaging modalities (including incoherent/coherent Raman scattering, two/three-photon luminescence, and second/third harmonic generations that have been amalgamated with plasmonics), as well as the novel subdiffraction limit imaging techniques based on nonlinear behaviors of plasmonic scattering, is addressed.

  1. Nonlinear plasmonic imaging techniques and their biological applications

    Directory of Open Access Journals (Sweden)

    Deka Gitanjal

    2016-07-01

    Full Text Available Nonlinear optics, when combined with microscopy, is known to provide advantages including novel contrast, deep tissue observation, and minimal invasiveness. In addition, special nonlinearities, such as switch on/off and saturation, can enhance the spatial resolution below the diffraction limit, revolutionizing the field of optical microscopy. These nonlinear imaging techniques are extremely useful for biological studies on various scales from molecules to cells to tissues. Nevertheless, in most cases, nonlinear optical interaction requires strong illumination, typically at least gigawatts per square centimeter intensity. Such strong illumination can cause significant phototoxicity or even photodamage to fragile biological samples. Therefore, it is highly desirable to find mechanisms that allow the reduction of illumination intensity. Surface plasmon, which is the collective oscillation of electrons in metal under light excitation, is capable of significantly enhancing the local field around the metal nanostructures and thus boosting up the efficiency of nonlinear optical interactions of the surrounding materials or of the metal itself. In this mini-review, we discuss the recent progress of plasmonics in nonlinear optical microscopy with a special focus on biological applications. The advancement of nonlinear imaging modalities (including incoherent/coherent Raman scattering, two/three-photon luminescence, and second/third harmonic generations that have been amalgamated with plasmonics, as well as the novel subdiffraction limit imaging techniques based on nonlinear behaviors of plasmonic scattering, is addressed.

  2. Quantum theory of many-body systems techniques and applications

    CERN Document Server

    Zagoskin, Alexandre

    2014-01-01

    This text presents a self-contained treatment of the physics of many-body systems from the point of view of condensed matter. The approach, quite traditionally, uses the mathematical formalism of quasiparticles and Green’s functions. In particular, it covers all the important diagram techniques for normal and superconducting systems, including the zero-temperature perturbation theory and the Matsubara, Keldysh and Nambu-Gor'kov formalism, as well as an introduction to Feynman path integrals. This new edition contains an introduction to the methods of theory of one-dimensional systems (bosonization and conformal field theory) and their applications to many-body problems.   Intended for graduate students in physics and related fields, the aim is not to be exhaustive, but to present enough detail to enable the student to follow the current research literature, or to apply the techniques to new problems. Many of the examples are drawn from mesoscopic physics, which deals with systems small enough that quantum...

  3. Techniques applicable for purifying Chironex fleckeri (box-jellyfish) venom.

    Science.gov (United States)

    Othman, I; Burnett, J W

    1990-01-01

    A survey of several techniques to isolate a purified lethal factor from the tentacles of Chironex fleckeri was completed. Heterologous band patterns were obtained from specific eluates after gel filtration, ion exchange, immunoaffinity and hydrophobic chromatography. SDS-PAGE revealed a dense band at 24,000 mol. wt in many of these fractions. Isoelectric focusing of the crude venom resulted in considerable loss of activity but indicated significant purification in the fractions having a pI of 5.2-6.8. These fractions were also immunologically active against sera from a convalescing post-evenomation patient. The primary difficulties encountered in jellyfish venom purification are the lack of stability and the tendency of the active toxins to adhere to each other and to various support matrices.

  4. Characterization of Brazilian wheat cultivars for specific technological applications

    Directory of Open Access Journals (Sweden)

    Patrícia Matos Scheuer

    2011-09-01

    Full Text Available Functional and technological properties of wheat depend on its chemical composition, which together with structural and microscopic characteristics, define flour quality. The aim of the present study was to characterize four Brazilian wheat cultivars (BRS Louro, BRS Timbauva, BRS Guamirim and BRS Pardela and their respective flours in order to indicate specific technological applications. Kernels were analyzed for test weight, thousand kernel weight, hardness, moisture, and water activity. Flours were analyzed for water activity, color, centesimal composition, total dietary fiber, amylose content and identification of high molecular weight glutenins. The rheological properties of the flours were estimated by farinography, extensography, falling number, rapid visco amylography, and glutomatic and glutork equipment. Baking tests and scanning electron microscopy were also performed. The data were subjected to analysis of variance and principal component analysis. BRS Timbauva and BRS Guamirim presented results that did not allow for specific technological application. On the other hand, BRS Louro presented suitable characteristics for the elaboration of products with low dough strength such as cakes, pies and biscuits, while BRS Pardela seemed suitable for bread and pasta products.

  5. New Complexity Scalable MPEG Encoding Techniques for Mobile Applications

    Directory of Open Access Journals (Sweden)

    Stephan Mietens

    2004-03-01

    Full Text Available Complexity scalability offers the advantage of one-time design of video applications for a large product family, including mobile devices, without the need of redesigning the applications on the algorithmic level to meet the requirements of the different products. In this paper, we present complexity scalable MPEG encoding having core modules with modifications for scalability. The interdependencies of the scalable modules and the system performance are evaluated. Experimental results show scalability giving a smooth change in complexity and corresponding video quality. Scalability is basically achieved by varying the number of computed DCT coefficients and the number of evaluated motion vectors but other modules are designed such they scale with the previous parameters. In the experiments using the “Stefan” sequence, the elapsed execution time of the scalable encoder, reflecting the computational complexity, can be gradually reduced to roughly 50% of its original execution time. The video quality scales between 20 dB and 48 dB PSNR with unity quantizer setting, and between 21.5 dB and 38.5 dB PSNR for different sequences targeting 1500 kbps. The implemented encoder and the scalability techniques can be successfully applied in mobile systems based on MPEG video compression.

  6. Video distribution techniques over WiMAX networks for m-Health applications.

    Science.gov (United States)

    Markarian, Garik; Mihaylova, Lyudmila; Tsitserov, Dmitry V; Zvikhachevskaya, A

    2012-01-01

    In this paper, we propose a novel approach for video distribution over IEEE 802.16 networks for mobile Healthcare (m-Health) applications. The technique incorporates resource distribution, scheduling, and content-aware video streaming taking advantage of a flexible quality of service functionality offered by IEEE 802.16/WiMAX technology. The proposed technique is thoroughly investigated using network simulator software under various real-life m-Health scenarios, which include streaming video over medium access control layer service connections. It is shown that the technique is fully compatible with the WiMAX standard specification and allows a 9-16% increase in the overall network throughput, which is dependent upon the initial system configuration and the selection of WiMAX user parameters.

  7. Evaluation of mesh morphing and mapping techniques in patient specific modelling of the human pelvis.

    Science.gov (United States)

    Salo, Zoryana; Beek, Maarten; Whyne, Cari Marisa

    2012-08-01

    Robust generation of pelvic finite element models is necessary to understand variation in mechanical behaviour resulting from differences in gender, aging, disease and injury. The objective of this study was to apply and evaluate mesh morphing and mapping techniques to facilitate the creation and structural analysis of specimen-specific finite element (FE) models of the pelvis. A specimen-specific pelvic FE model (source mesh) was generated following a traditional user-intensive meshing scheme. The source mesh was morphed onto a computed tomography scan generated target surface of a second pelvis using a landmarked-based approach, in which exterior source nodes were shifted to target surface vertices, while constrained along a normal. A second copy of the morphed model was further refined through mesh mapping, in which surface nodes of the initial morphed model were selected in patches and remapped onto the surfaces of the target model. Computed tomography intensity-based material properties were assigned to each model. The source, target, morphed and mapped models were analyzed under axial compression using linear static FE analysis, and their strain distributions were evaluated. Morphing and mapping techniques were effectively applied to generate good quality and geometrically complex specimen-specific pelvic FE models. Mapping significantly improved strain concurrence with the target pelvis FE model.

  8. Specificity of noninvasive blood glucose sensing using optical coherence tomography technique: a pilot study.

    Science.gov (United States)

    Larin, Kirill V; Motamedi, Massoud; Ashitkov, Taras V; Esenaliev, Rinat O

    2003-05-21

    Noninvasive monitoring of blood glucose concentration in diabetic patients would significantly reduce complications and mortality associated with this disease. In this paper, we experimentally and theoretically studied specificity of noninvasive blood glucose monitoring with the optical coherence tomography (OCT) technique. OCT images and signals were obtained from skin of Yucatan micropigs and New Zealand rabbits. Obtained results demonstrate that: (1) several body osmolytes may change the refractive index mismatch between the interstitial fluid (ISF) and scattering centres in tissue, however the effect of the glucose is approximately one to two orders of magnitude higher; (2) an increase of the ISF glucose concentration in the physiological range (3-30 mM) may decrease the scattering coefficient by 0.22% mM(-1) due to cell volume change; (3) stability of the OCT signal slope is dependent on tissue heterogeneity and motion artefacts; and (4) moderate skin temperature fluctuations (+/- 1 degree C) do not decrease accuracy and specificity of the OCT-based glucose sensor, however substantial skin heating or cooling (several degrees C) significantly change the OCT signal slope. These results suggest that the OCT technique may provide blood glucose concentration monitoring with sufficient specificity under normal physiological conditions.

  9. Splintless orthognathic surgery: a novel technique using patient-specific implants (PSI).

    Science.gov (United States)

    Gander, Thomas; Bredell, Marius; Eliades, Theodore; Rücker, Martin; Essig, Harald

    2015-04-01

    In the past few years, advances in three-dimensional imaging have conducted to breakthrough in the diagnosis, treatment planning and result assessment in orthognathic surgery. Hereby error-prone and time-consuming planning steps, like model surgery and transfer of the face bow, can be eluded. Numerous positioning devices, in order to transfer the three-dimensional treatment plan to the intraoperative site, have been described. Nevertheless the use of positioning devices and intraoperative splints are failure-prone and time-consuming steps, which have to be performed during the operation and during general anesthesia of the patient. We describe a novel time-sparing and failsafe technique using patient-specific implants (PSI) as positioning guides and concurrently as rigid fixation of the maxilla in the planned position. This technique avoids elaborate positioning and removal of manufactured positioning devices and allows maxillary positioning without the use of occlusal splints.

  10. Analytical Electrochemistry: Methodology and Applications of Dynamic Techniques.

    Science.gov (United States)

    Heineman, William R.; Kissinger, Peter T.

    1980-01-01

    Reports developments involving the experimental aspects of finite and current analytical electrochemistry including electrode materials (97 cited references), hydrodynamic techniques (56), spectroelectrochemistry (62), stripping voltammetry (70), voltammetric techniques (27), polarographic techniques (59), and miscellany (12). (CS)

  11. Task-specific singing dystonia: vocal instability that technique cannot fix.

    Science.gov (United States)

    Halstead, Lucinda A; McBroom, Deanna M; Bonilha, Heather Shaw

    2015-01-01

    Singer's dystonia is a rare variation of focal laryngeal dystonia presenting only during specific tasks in the singing voice. It is underdiagnosed since it is commonly attributed to technique problems including increased muscle tension, register transition, or wobble. Singer's dystonia differs from technique-related issues in that it is task- and/or pitch-specific, reproducible and occurs independently from the previously mentioned technical issues.This case series compares and contrasts profiles of four patients with singer's dystonia to increase our knowledge of this disorder. This retrospective case series includes a detailed case history, results of singing evaluations from individual voice teachers, review of singing voice samples by a singing voice specialist, evaluation by a laryngologist with endoscopy and laryngeal electromyography (LEMG), and spectral analysis of the voice samples by a speech-language pathologist. Results demonstrate the similarities and unique differences of individuals with singer's dystonia. Response to treatment and singing status varied from nearly complete relief of symptoms with botulinum toxin injections to minor relief of symptoms and discontinuation of singing. The following are the conclusions from this case series: (1) singer's dystonia exists as a separate entity from technique issues, (2) singer's dystonia is consistent with other focal task-specific dystonias found in musicians, (3) correctly diagnosing singer's dystonia allows singer's access to medical treatment of dystonia and an opportunity to modify their singing repertoire to continue singing with the voice they have, and (4) diagnosis of singer's dystonia requires careful sequential multidisciplinary evaluation to isolate the instability and confirm dystonia by LEMG and spectral voice analysis. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  12. Lithographically defined shape-specific polymeric particulates for nanomedicine application

    Science.gov (United States)

    Tao, Li

    Size and shape are fundamental properties of micro/nano particles that are critically important for nanomedicine applications. Extensive studies have revealed the effect particle size has on spherical particles with respect to biological behaviors such as blood circulation time or targeting efficacy to specific receptors on the cell. In contrast, the importance of particle shape has been less understood. The major contributing factor is that conventional bottom-up fabrication methods are limited in their ability to control the shape of polymeric particles precisely. This dissertation will mainly focus on the development of top-down platforms to fabricate shape-specific polymeric particles. Shape-specific polymeric particles incorporated with fluorescent or magnetic agents were demonstrated with high uniformity. Microfluidic testing platform was built to verify the shape effect on the flow behavior of fabricated particles. The fabrication platform developed here opened up the opportunity to perform fundamental study on how shape can alter the biological behavior of polymeric nanomedicine, thus leading to a more rational design of nanomedicine with enhanced efficacy but reduced toxicity.

  13. Literature Review of Cosmetic Procedures in Men: Approaches and Techniques are Gender Specific.

    Science.gov (United States)

    Cohen, Brandon E; Bashey, Sameer; Wysong, Ashley

    2017-02-01

    The proportion of men receiving non-surgical cosmetic procedures has risen substantially in recent years. Various physiologic, anatomic, and motivational considerations differentiate the treatments for male and female patients. Nevertheless, research regarding approaches to the male cosmetic patient is scarce. We sought to provide an overview and sex-specific discussion of the most popular cosmetic dermatologic procedures pursued by men by conducting a comprehensive literature review pertaining to non-surgical cosmetic procedures in male patients. The most common and rapidly expanding non-surgical interventions in men include botulinum toxin, filler injection, chemical peels, microdermabrasion, laser resurfacing, laser hair removal, hair transplantation, and minimally invasive techniques for adipose tissue reduction. Important sex-specific factors associated with each of these procedures should be considered to best serve the male cosmetic patient.

  14. Multimodality Image Fusion-Guided Procedures: Technique, Accuracy, and Applications

    Energy Technology Data Exchange (ETDEWEB)

    Abi-Jaoudeh, Nadine, E-mail: naj@mail.nih.gov [National Institutes of Health, Radiology and Imaging Sciences (United States); Kruecker, Jochen, E-mail: jochen.kruecker@philips.com [Philips Research North America (United States); Kadoury, Samuel, E-mail: samuel.kadoury@polymtl.ca [Ecole Polytechnique de Montreal, Department of Computer and Software Engineering, Institute of Biomedical Engineering (Canada); Kobeiter, Hicham, E-mail: hicham.kobeiter@gmail.com [CHU Henri Mondor, UPEC, Departments of Radiology and d' imagrie medicale (France); Venkatesan, Aradhana M., E-mail: VenkatesanA@cc.nih.gov; Levy, Elliot, E-mail: levyeb@cc.nih.gov; Wood, Bradford J., E-mail: bwood@cc.nih.gov [National Institutes of Health, Radiology and Imaging Sciences (United States)

    2012-10-15

    Personalized therapies play an increasingly critical role in cancer care: Image guidance with multimodality image fusion facilitates the targeting of specific tissue for tissue characterization and plays a role in drug discovery and optimization of tailored therapies. Positron-emission tomography (PET), magnetic resonance imaging (MRI), and contrast-enhanced computed tomography (CT) may offer additional information not otherwise available to the operator during minimally invasive image-guided procedures, such as biopsy and ablation. With use of multimodality image fusion for image-guided interventions, navigation with advanced modalities does not require the physical presence of the PET, MRI, or CT imaging system. Several commercially available methods of image-fusion and device navigation are reviewed along with an explanation of common tracking hardware and software. An overview of current clinical applications for multimodality navigation is provided.

  15. Current issues in the treatment of specific phobia: recommendations for innovative applications of hypnosis.

    Science.gov (United States)

    Spiegel, Sharon B

    2014-04-01

    Specific phobia is the most common and treatable of the anxiety disorders. Exposure-based therapies are the treatment of choice and empirically validated protocols are available that promise rapid and effective results. In many cases, however, patients are reluctant to comply with demanding schedules of exposure, increasing the risk of treatment failure. Furthermore, in clinical practice, patients often present with multiple phobias and other Axis I and Axis II disorders that can further complicate therapy. This article covers four important issues that have been addressed in the literature: (a) managing resistance to treatment, (b) reducing length of treatment, (c) clarifying the optimal application of relaxation training, and (d) applying advances in cognitive neuroscience. These issues are reviewed and recommendations proposed for ways in which to modify current treatments. Specific suggestions are provided for implementing these recommendations including examples of innovative applications of standard hypnotic techniques.

  16. The Application of TAPM for Site Specific Wind Energy Forecasting

    Directory of Open Access Journals (Sweden)

    Merlinde Kay

    2016-02-01

    Full Text Available The energy industry uses weather forecasts for determining future electricity demand variations due to the impact of weather, e.g., temperature and precipitation. However, as a greater component of electricity generation comes from intermittent renewable sources such as wind and solar, weather forecasting techniques need to now also focus on predicting renewable energy supply, which means adapting our prediction models to these site specific resources. This work assesses the performance of The Air Pollution Model (TAPM, and demonstrates that significant improvements can be made to only wind speed forecasts from a mesoscale Numerical Weather Prediction (NWP model. For this study, a wind farm site situated in North-west Tasmania, Australia was investigated. I present an analysis of the accuracy of hourly NWP and bias corrected wind speed forecasts over 12 months spanning 2005. This extensive time frame allows an in-depth analysis of various wind speed regimes of importance for wind-farm operation, as well as extreme weather risk scenarios. A further correction is made to the basic bias correction to improve the forecast accuracy further, that makes use of real-time wind-turbine data and a smoothing function to correct for timing-related issues. With full correction applied, a reduction in the error in the magnitude of the wind speed by as much as 50% for “hour ahead” forecasts specific to the wind-farm site has been obtained.

  17. Vapor generation – atomic spectrometric techniques. Expanding frontiers through specific-species preconcentration. A review

    Energy Technology Data Exchange (ETDEWEB)

    Gil, Raúl A.; Pacheco, Pablo H.; Cerutti, Soledad [Área de Química Analítica, Facultad de Química Bioquímica y Farmacia, Universidad Nacional de San Luis, Ciudad de San Luis 5700 (Argentina); Instituto de Química de San Luis, INQUISAL, Centro Científico-Tecnológico de San Luis (CCT-San Luis), Consejo Nacional de Investigaciones Científicas y Universidad Nacional de San Luis, Ciudad de San Luis 5700 (Argentina); Martinez, Luis D., E-mail: ldm@unsl.edu.ar [Área de Química Analítica, Facultad de Química Bioquímica y Farmacia, Universidad Nacional de San Luis, Ciudad de San Luis 5700 (Argentina); Instituto de Química de San Luis, INQUISAL, Centro Científico-Tecnológico de San Luis (CCT-San Luis), Consejo Nacional de Investigaciones Científicas y Universidad Nacional de San Luis, Ciudad de San Luis 5700 (Argentina)

    2015-05-22

    This article reviews 120 articles found in SCOPUS and specific Journal cites corresponding to the terms ‘preconcentration’; ‘speciation’; ‘vapor generation techniques’ and ‘atomic spectrometry techniques’ in the last 5 years. - Highlights: • Recent advances in vapor generation and atomic spectrometry were reviewed. • Species-specific preconcentration strategies after and before VG were discussed. • New preconcentration and speciation analysis were evaluated within this framework. - Abstract: We review recent progress in preconcentration strategies associated to vapor generation techniques coupled to atomic spectrometric (VGT-AS) for specific chemical species detection. This discussion focuses on the central role of different preconcentration approaches, both before and after VG process. The former was based on the classical solid phase and liquid–liquid extraction procedures which, aided by automation and miniaturization strategies, have strengthened the role of VGT-AS in several research fields including environmental, clinical, and others. We then examine some of the new vapor trapping strategies (atom-trapping, hydride trapping, cryotrapping) that entail improvements in selectivity through interference elimination, but also they allow reaching ultra-low detection limits for a large number of chemical species generated in conventional VG systems, including complete separation of several species of the same element. This review covers more than 100 bibliographic references from 2009 up to date, found in SCOPUS database and in individual searches in specific journals. We finally conclude by giving some outlook on future directions of this field.

  18. 46 CFR 24.05-5 - Specific application noted in text.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Specific application noted in text. 24.05-5 Section 24... Application § 24.05-5 Specific application noted in text. (a) At the beginning of the various parts, subparts, and sections, a more specific application is generally given for the particular portion of the...

  19. The specifics of dosimetry for food irradiation applications

    Science.gov (United States)

    Kuntz, Florent; Strasser, Alain

    2016-12-01

    Dose measurement applied to food irradiation is obviously a very important and critical aspect of this process. It is described in many standards and guides. The application of appropriate dosimetry tools is explained. This helps to ensure traceability of this measurement and number of dosimeters available on the market are well studied even though theirs response should be characterized while used in routine processing conditions. When employed in low energy radiation fields, these dosimeters may exhibit specific response compared to the usual Cobalt 60 source irradiation. Traceable calibration or correction factor assessment of this energy dependency is mandatory. It is to mention that the absorbed dose is measured in the dosimeter itself and unfortunately not in/on the food product. However, existing dosimetry systems fulfill all relevant requirements.

  20. Improvement and Primary Application of Theory of Fuel Specific Consumption

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The high efficiency utilization of energy conversion systems has been regarded as one of the most effective ways to cope with the everincreasing depletion of fossil fuel and the greenhouse gas effect. The design, optimization and refurbishment of thermal systems definitely need the help of proper application of energy conservation theory, especially exergy analysis. Conventional exergy analysis only considers the energy consumption of each device in isolation without taking the interactions among devices into consideration. In addition, the exergy destruction and exergetic efficiency are always the criterion for the evaluation of the device performances; however, great controversies exist. This paper presents the development of fuel specific consumption analysis considering the interactions among devices to provide more information for energy-savings of thermal systems.

  1. Applications of Mapping and Tomographic Techniques in Gem Sciences

    Science.gov (United States)

    Shen, A. H.

    2014-12-01

    Gem Sciences are scientific studies of gemstones - their genesis, provenance, synthesis, enhancement, treatment and identification. As high quality forms of specific minerals, the gemstones exhibit unusual physical properties that are usually unseen in the regular counterparts. Most gemstones are colored by trace elements incorporated in the crystal lattice during various growth stages; forming coloration zones of various scales. Studying the spectral and chemical contrast across color zones helps elucidating the origins of colors. These are done by UV-visible spectrometers with microscope and LA-ICPMS in modern gemological laboratories. In the case of diamonds, their colored zones arise from various structural defects incorporated in different growth zones and are studied with FTIR spectrometers with IR microscope and laser photoluminescence spectrometers. Advancement in modern synthetic techniques such as chemical vapor deposition (CVD) has created some problem for identification. Some exploratory experiments in carbon isotope mapping were done on diamonds using SIMS. The most important issue in pearls is to identify one particular pearl being a cultured one or a natural pearl. The price difference can be enormous. Classical way of such identification is done by x-ray radiographs, which clearly show the bead and the nacre. Modern cultured pearl advancement has eliminated the need for an artificial bead, but a small piece of tissue instead. Nowadays, computer x-ray tomography (CT) scanning devices are used to depict the clear image of the interior of a pearl. In the Chinese jade market, filling fissures with epoxy and/or wax are very commonly seen. We are currently exploring Magnetic Resonance Imaging (MRI) technique to map the distribution of artificial resin within a polycrystalline aggregates.

  2. EVALUATION OF VARIOUS COMPILER OPTIMIZATION TECHNIQUES RELATED TO MIBENCH BENCHMARK APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Jeyaraj Andrews

    2013-01-01

    Full Text Available Tuning compiler optimization for a given application of particular computer architecture is not an easy task, because modern computer architecture reaches higher levels of compiler optimization. These modern compilers usually provide a larger number of optimization techniques. By applying all these techniques to a given application degrade the program performance as well as more time consuming. The performance of the program measured by time and space depends on the machine architecture, problem domain and the settings of the compiler. The brute-force method of trying all possible combinations would be infeasible, as it’s complexity O(2n even for “n” on-off optimizations. Even though many existing techniques are available to search the space of compiler options to find optimal settings, most of those approaches can be expensive and time consuming. In this study, machine learning algorithm has been modified and used to reduce the complexity of selecting suitable compiler options for programs running on a specific hardware platform. This machine learning algorithm is compared with advanced combined elimination strategy to determine tuning time and normalized tuning time. The experiment is conducted on core i7 processor. These algorithms are tested with different mibench benchmark applications. It has been observed that performance achieved by a machine learning algorithm is better than advanced combined elimination strategy algorithm.

  3. Nano-computed tomography. Technique and applications; Nanocomputertomografie. Technik und Applikationen

    Energy Technology Data Exchange (ETDEWEB)

    Kampschulte, M.; Sender, J.; Litzlbauer, H.D.; Althoehn, U.; Schwab, J.D.; Alejandre-Lafont, E.; Martels, G.; Krombach, G.A. [University Hospital Giessen (Germany). Dept. of Diagnostic and Interventional Radiology; Langheinirch, A.C. [BG Trauma Hospital Frankfurt/Main (Germany). Dept. of Diagnostic and Interventional Radiology

    2016-02-15

    Nano-computed tomography (nano-CT) is an emerging, high-resolution cross-sectional imaging technique and represents a technical advancement of the established micro-CT technology. Based on the application of a transmission target X-ray tube, the focal spot size can be decreased down to diameters less than 400 nanometers (nm). Together with specific detectors and examination protocols, a superior spatial resolution up to 400 nm (10 % MTF) can be achieved, thereby exceeding the resolution capacity of typical micro-CT systems. The technical concept of nano-CT imaging as well as the basics of specimen preparation are demonstrated exemplarily. Characteristics of atherosclerotic plaques (intraplaque hemorrhage and calcifications) in a murine model of atherosclerosis (ApoE{sub (-/-)}/LDLR{sub (-/-)} double knockout mouse) are demonstrated in the context of superior spatial resolution in comparison to micro-CT. Furthermore, this article presents the application of nano-CT for imaging cerebral microcirculation (murine), lung structures (porcine), and trabecular microstructure (ovine) in contrast to micro-CT imaging. This review shows the potential of nano-CT as a radiological method in biomedical basic research and discusses the application of experimental, high resolution CT techniques in consideration of other high resolution cross-sectional imaging techniques.

  4. Hybrid specification, storage, retrieval and runtime application of clinical guidelines.

    Science.gov (United States)

    Shahar, Y

    2006-06-01

    Clinical guidelines are a major tool in improving the quality of medical care. However, most guidelines are in free text, are not machine-comprehensible and are not easily accessible to clinicians at the point of care. We have designed and implemented a web-based, modular, distributed architecture, the Digital Electronic Guideline Library (DeGeL), which facilitates gradual conversion of clinical guidelines from text to a formal representation in the chosen target guideline ontology. The architecture supports guideline classification, semantic markup, context-sensitive search, browsing, run-time application and retrospective quality assessment. The DeGeL hybrid meta-ontology includes elements common to all guideline ontologies, such as semantic classification and domain knowledge; it also includes four content-representation formats: free text, semi-structured text, semi-formal representation and a formal representation. These formats support increasingly sophisticated computational tasks. Guidelines can thus be in a hybrid representation in which guidelines, and even parts of the same guideline, might exist at different formalisation levels. We have also developed and rigorously evaluated a methodology and an associated web-based tool, Uruz, for gradually structuring and semi-formalising free-text clinical guidelines. Finally, we have designed, implemented and evaluated a new approach, the hybrid runtime application model, for supporting runtime application of clinical guidelines that are not necessarily in a machine-comprehensible format; in particular, when the guideline is in a semi-formal representation and the patient's data are either in an electronic medical record or in a paper format. The tool implementing this new approach, the Spock module, is customised at this point to the Asbru guideline specification language and exploits the hybrid structure of guidelines in DeGeL. The Spock module also exploits our temporal-abstraction mediator to the patient

  5. CARBON NANOTUBES: A REVIEW ON PREPARATION TECHNIQUES AND APPLICATIONS IN VARIOUS FIELDS

    Directory of Open Access Journals (Sweden)

    SaiSowjanya Palla

    2013-02-01

    Full Text Available Carbon nanotubes (CNTs are allotropes of carbon with a nanostructure that can have a length-to-diameter ratio greater than 1,000,000. Different types of carbon nanotubes can be produced by different methods: Arc discharge, laser ablation, chemical vapour deposition and flame synthesis. Purification of the tubes can be divided into a couple of main techniques: oxidation, acid treatment, annealing, sonication, filtering and functionalisation techniques. Economically feasible large-scale production and purification techniques still have to be developed. Fundamental and practical nanotube researches have shown possible applications in the fields of energy storage, molecular electronics, nanomechanic devices, composite materials and immobilization of enzymes. Various immobilization methods have been developed, and in particular, specific attachment of enzymes on carbon nanotubes has been an important focus of attention. With the growing attention paid to cascade enzymatic reaction, it is possible that multi enzyme co-immobilization would be one of the next goals in the future. In this paper, we focus on preparation techniques, various applications of CNTs and enzyme immobilization on carbon nanotubes.

  6. Key Techniques and Application Progress of Molecular Pharmacognosy

    Institute of Scientific and Technical Information of China (English)

    XIAO Xue-feng; HU Jing; XU Hai-yu; GAO Wen-yuan; ZHANG Tie-jun; LIU Chang-xiao

    2011-01-01

    At the boundary between pharmacognosy and molecular biology, molecular pharmacognosy has developed as a new borderline discipline. This paper reviews the methods, application, and prospect of molecular pharmacognosy. DNA marker is one of genetic markers and some molecular marker methods which have been successfully used for genetic diversity identification and new medicinal resources development. Recombinant DNA technology provides a powerful tool that enables scientists to engineer DNA sequences. Gene chip technique could be used in determination of gene expression profiles, analyses of polymorphisms, construction of genomic library, analysis of mapping, and sequencing by hybridization. Using the methods and theory of molecular biology and pharmacognosy, molecular pharmacognosy represents an extremely prospective branch of pharmacognosy and focuses on the study of systemic growth of medicinal plants, identification and evaluation of germplasm resources, plant metabolomics and production of active compounds. Furthermore, the great breakthrough of molecular pharmacognosy could be anticipated on DNA fingerprint analysis, cultivar improvement, DNA identification, and a global DNA barcoding system in the future.

  7. Hot gas stream application in micro-bonding technique

    Science.gov (United States)

    Andrijasevic, Daniela; Giouroudi, Ioanna; Smetana, Walter; Boehm, Stefan; Brenner, Werner

    2006-01-01

    This paper presents a new concept for bonding micro-parts with dimensions in the range of 50 μm to 300 μm. Two different kinds of adhesives - polyurethane adhesive foil and hot melt glue - were applied to a basic substrate by different techniques. The focused and concentrated hot gas stream softened glue which had been applied in a solid state. Micro-parts were then embossed in the softened glue, or covered and shielded by it. In this way, a rigid and compact bond was obtained after cooling. For the positioning of micro-parts (optical fibers), it has been necessary to manufacture adequate V-grooves. Finite element analyses using the ANSYS TM program package were performed in order to evaluate parameters which govern the heat transfer to the adhesive and substrate respectively. Experimental results are in good agreement with results obtained by the numerical simulations. The advantages of this new approach are small system size, low capital costs, simple usage, applicability to many material combinations, easy integration into existing production lines, etc.

  8. Exploring Gamification Techniques and Applications for Sustainable Tourism

    Directory of Open Access Journals (Sweden)

    Adina Letiţia Negruşa

    2015-08-01

    Full Text Available Tourism is perceived as an appropriate solution for pursuing sustainable economic growth due to its main characteristics. In the context of sustainable tourism, gamification can act as an interface between tourists (clients, organisations (companies, NGOs, public institutions and community, an interface built in a responsible and ethical way. The main objective of this study is to identify gamification techniques and applications used by organisations in the hospitality and tourism industry to improve their sustainable activities. The first part of the paper examines the relationship between gamification and sustainability, highlighting the links between these two concepts. The second part identifies success stories of gamification applied in hospitality and tourism and reviews gamification benefits by analysing the relationship between tourism organisations and three main tourism stakeholders: tourists, tourism employees and local community. The analysis is made in connection with the main pillars of sustainability: economic, social and environmental. This study is positioning the role of gamification in the tourism and hospitality industry and further, into the larger context of sustainable development.

  9. Multiplex-FISH (M-FISH): technique, developments and applications.

    Science.gov (United States)

    Kearney, L

    2006-01-01

    Multiplex FISH (M-FISH) represents one of the most significant developments in molecular cytogenetics of the past decade. Originally designed to generate 24 colour karyotyping, the technique has spawned many variations and an equally diverse range of applications. In tumour and leukaemia cytogenetics, the two groups that have been targeted represent both ends of the cytogenetic spectrum: those with an apparently normal karyotype (suspected of harbouring small rearrangements not detectable by conventional cytogenetics) and those with a complex aberrant karyotype (which are difficult to karyotype accurately due to the sheer number of aberrations). In research, mouse M-FISH provides a powerful tool to characterize mouse models of a disease. In addition, the ability to accurately karyotype single metaphases without selection makes M-FISH the perfect tool in chromosome breakage studies and for characterizing clonal evolution of tumours. Finally, M-FISH has emerged as the perfect partner for the developing genomic microarray (array CGH) technologies, providing a powerful approach to gene discovery.

  10. Techniques of DNA methylation analysis with nutritional applications.

    Science.gov (United States)

    Mansego, Maria L; Milagro, Fermín I; Campión, Javier; Martínez, J Alfredo

    2013-01-01

    Epigenetic mechanisms are likely to play an important role in the regulation of metabolism and body weight through gene-nutrient interactions. This review focuses on methods for analyzing one of the most important epigenetic mechanisms, DNA methylation, from single nucleotide to global measurement depending on the study goal and scope. In addition, this study highlights the major principles and methods for DNA methylation analysis with emphasis on nutritional applications. Recent developments concerning epigenetic technologies are showing promising results of DNA methylation levels at a single-base resolution and provide the ability to differentiate between 5-methylcytosine and other nucleotide modifications such as 5-hydroxymethylcytosine. A large number of methods can be used for the analysis of DNA methylation such as pyrosequencing™, primer extension or real-time PCR methods, and genome-wide DNA methylation profile from microarray or sequencing-based methods. Researchers should conduct a preliminary analysis focused on the type of validation and information provided by each technique in order to select the best method fitting for their nutritional research interests.

  11. Development and application of simulation technique for hydrokinetic hammer

    Institute of Scientific and Technical Information of China (English)

    Tianye ZHU; Qingyan WANG; Kun YIN; Siyi WANG

    2007-01-01

    The computer simulation is an important method for hydrokinetic hammer design. Various kinds of simulation measures with their technical characters and applications being taken during the computer aided design are enumerated. Computer simulation supports plenty of valuable references to the designer. Each type of simulation process is used to explore the exact aspect of the performance of hydrokinetic hammer and each type of simulation method has its own excellences and deficiencies. Thus the integrative simulation methods based on modern computational technology are brought forward to obtain the perfect capability of the whole product. Along with the development of computer hardware and software, various kinds of platforms have been provided to different simulation methods that can be carried out with distinct working flows. The jet flow element is the core part of the hydrokinetic hammer. We can build the ideal simulation model of it by means of CFD (computational fluid dynamics) technology. On the other hand, to set up the digital model of piston and hammer, the best way is to build the virtual prototype using automatic dynamic analysis of mechanical system. As a result of the argumentation, we think the technique of Virtual Prototype and CFD are the prime way to process the combined computer simulation for hydrokinetic hammer.

  12. Application of Dynamic Speckle Techniques in Monitoring Biofilms Drying Process

    Science.gov (United States)

    Enes, Adilson M.; Júnior, Roberto A. Braga; Dal Fabbro, Inácio M.; da Silva, Washington A.; Pereira, Joelma

    2008-04-01

    Horticultural crops exhibit losses far greater than grains in Brazil which are associated to inappropriate maturation, mechanical bruising, infestation by microorganisms, wilting, etc. Appropriate packing prevents excessive mass loss associated to transpiration as well as to respiration, by controlling gas exchanging with outside environment. Common packing materials are identified as plastic films, waxes and biofilms. Although research developed with edible films and biopolymers has increased during last years to attend the food industry demands, avoiding environmental problems, little efforts have been reported on biofilm physical properties investigations. These properties, as drying time and biofilm interactions with environment are considered of basic importance. This research work aimed to contribute to development of a methodology to evaluate yucca (Maniot vulgaris) based biofilms drying time supported by a biospeckle technique. Biospeckle is a phenomenon generated by a laser beam scattered on a dynamic active surface, producing a time varying pattern which is proportional to the surface activity level. By capturing and processing the biospeckle image it is possible to attribute a numerical quantity to the surface bioactivity. Materials exhibiting high moisture content will also show high activity, which will support the drying time determination. Tests were set by placing biofilm samples on polyetilen plates and further submitted to laser exposition at four hours interval to capture the pattern images, generating the Intensities Dispersion Modulus. Results indicates that proposed methodology is applicable in determining biofilm drying time as well as vapor losses to environment.

  13. Investigation of microwave hologram techniques for application to earth resources

    Science.gov (United States)

    Larson, R. W.; Bayma, R. W.; Evans, M. B.; Zelenka, J. S.; Doss, H. W.; Ferris, J. E.

    1974-01-01

    An investigation of microwave hologram techniques for application to earth resources was conducted during the period from June 1971 to November 1972. The objective of this investigation has been to verify the feasibility of an orbital microwave holographic radar experiment. The primary advantage of microwave hologram radar (MHR) over the side-looking airborne radar (SLAR) is that of aspect or viewing angle; the MHR has a viewing angle identical with that of photography and IR systems. The combination of these systems can thus extend the multispectral analysis concept to span optical through microwave wavelengths. Another advantage is the capacity of the MHR system to generate range contours by operating in a two-frequency mode. It should be clear that along-track resolution of an MHR can be comparable with SLAR systems, but cross-track resolution will be approximately an order of magnitude coarser than the range resolution achievable with an arbitrary SLAR system. An advantage of the MHR over the SLAR is that less average transmitter power is required. This reduction in power results from the much larger receiving apertures associated with MHR systems.

  14. MR angiography of the body. Technique and clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Neri, Emanuele [Pisa Univ. Radiodiagnostica 1 Universitaria (Italy). Diagnostic and Interventional Radiology Dept. of Oncology, Transplants, and Advanced Technologies in Medicine; Cosottini, Mirco [Pisa Univ. (Italy). Unit of Neuroradiology Dept. of Neurosciences; Caramella, Davide (eds.) [Pisa Univ. (Italy). Diagnostic and Interventional Radiology Dept. of Oncology, Transplants, and Advanced Technologies in Medicine

    2010-07-01

    Magnetic resonance angiography (MRA) continues to undergo exciting technological advances that are rapidly being translated into clinical practice. It also has evident advantages over other imaging modalities, including better patient safety compared with CT angiography and superior accuracy and contrast resolution compared with ultrasonography. With the aid of numerous high-quality illustrations, this book reviews the current role of MRA of the body. It is divided into three sections. The first section is devoted to issues relating to image acquisition technique and sequences. Individual chapters focus on flow-based MRA, contrast media, contrast-enhanced MRA, artifacts, and image processing. The second and principal section of the book addresses the clinical applications of MRA in various parts of the body, including the neck vessels, the spine, the thoracic aorta and pulmonary vessels, the heart and coronary arteries, the abdominal aorta and renal arteries, and peripheral vessels. The role of the blood pool contrast agents for the diagnosis and characterization of vascular disease is fully explored. The final section considers the role of MRA in patients undergoing liver or pancreas and kidney transplantation. This book will be an invaluable aid to all radiologists who work with MRA. (orig.)

  15. Surgical Tips in Frozen Abdomen Management: Application of Coliseum Technique

    Directory of Open Access Journals (Sweden)

    Ioannis D. Kyriazanos

    2015-01-01

    Full Text Available Wound dehiscence is a serious postoperative complication, with an incidence of 0.5–3% after primary closure of a laparotomy incision, and represents an acute mechanical failure of wound healing. Relatively recently the concept of “intentional open abdomen” was described and both clinical entities share common pathophysiological and clinical pathways (“postoperative open abdominal wall”. Although early reconstruction is the target, a significant proportion of patients will develop adhesions between abdominal viscera and the anterolateral abdominal wall, a condition widely recognized as “frozen abdomen,” where delayed wound closure appears as the only realistic alternative. We report our experience with a patient who presented with frozen abdomen after wound dehiscence due to surgical site infection and application of the “Coliseum technique” for its definitive surgical management. This novel technique represents an innovative alternative to abdominal exploration, for cases of “malignant” frozen abdomen due to peritoneal carcinomatosis. Lifting the edges of the surgical wound upwards and suspending them under traction by threads from a retractor positioned above the abdomen facilitates approach to the peritoneal cavity, optimizes exposure of intra-abdominal organs, and prevents operative injury to the innervation and blood supply of abdominal wall musculature, a crucial step for subsequent hernia repair.

  16. Application of Isothermal Amplification Techniques for Identification of Madurella mycetomatis, the Prevalent Agent of Human Mycetoma.

    Science.gov (United States)

    Ahmed, Sarah A; van de Sande, Wendy W J; Desnos-Ollivier, Marie; Fahal, Ahmed H; Mhmoud, Najwa A; de Hoog, G S

    2015-10-01

    Appropriate diagnosis and treatment of eumycetoma may vary significantly depending on the causative agent. To date, the most common fungus causing mycetoma worldwide is Madurella mycetomatis. This species fails to express any recognizable morphological characteristics, and reliable identification can therefore only be achieved with the application of molecular techniques. Recombinase polymerase amplification (RPA) and loop-mediated isothermal amplification (LAMP) are proposed as alternatives to phenotypic methods. Species-specific primers were developed to target the ribosomal DNA (rDNA) internal transcribed spacer (ITS) region of M. mycetomatis. Both isothermal amplification techniques showed high specificity and sufficient sensitivity to amplify fungal DNA and proved to be appropriate for detection of M. mycetomatis. Diagnostic performance of the techniques was assessed in comparison to conventional PCR using biopsy specimens from eumycetoma patients. RPA is reliable and easy to operate and has the potential to be implemented in areas where mycetoma is endemic. The techniques may be expanded to detect fungal DNA from environmental samples. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  17. Application of Thin Bed Log Evaluation Techniques in Dagang Oilfield

    Institute of Scientific and Technical Information of China (English)

    Fan Zhiren; Jiao Cuihua; Liu Dewu; Heng zhi

    1995-01-01

    @@ Some techniques are presented in this paper through which vertical resolution of individual logs can be increased by mathematical and geological ana lysis methods. These techniques provide a solid basis for accurate delineation and evaluation of thin beds.

  18. Two applications of airtightness control techniques on big assemblies

    CERN Document Server

    Devallan, C; Marcellin, J

    1973-01-01

    Deals with two airtightness control techniques respectively applied on intersecting storage rings (ISR) at CERN in Geneva and on a liquid methane storage tank. These two big assemblies called for two different control techniques which use helium and ammonia respectively as tracer gas. Existing practical leakage detection techniques to meet industrial needs are discussed at the end of the article. (2 refs).

  19. Application of nuclear techniques in Poland; Perspektywy wykorzystania atomistyki w Polsce

    Energy Technology Data Exchange (ETDEWEB)

    Chmielewski, A.G.; Owczarczyk, A.; Urbanski, P. [Instytut Chemii i Techniki Jadrowej, Warsaw (Poland); Romanowski, M. [Biuro Studiow i Projektow Techniki Jadrowej `Proatom`, Warsaw (Poland); Stegowski, Z. [Akademia Gorniczo-Hutnicza, Cracow (Poland); Nowak, K. [Osrodek Badawczo-Rozwojowy Izotopow, Swierk-Otwock (Poland); Pachan, A. [Instytut Problemow Jadrowych, Swierk-Otwock (Poland); Tanczyk, R. [Centralne Laboratorium Ochrony Radiologicznej, Warsaw (Poland); Jablonski, R. [Zaklad Techniki Izotopowej `Polon-Izot`, Warsaw (Poland)

    1997-12-31

    The commercial applications of nuclear techniques in Poland have been presented. The special attention have been paid at: radiation technologies, application of radiometric gages in different branches of industry, tracer techniques, production and application of radiation sources in medicine, industry and material testing. 10 refs, 6 figs, 6 tabs.

  20. Innovative application of virtual display technique in virtual museum

    Science.gov (United States)

    Zhang, Jiankang

    2017-09-01

    Virtual museum refers to display and simulate the functions of real museum on the Internet in the form of 3 Dimensions virtual reality by applying interactive programs. Based on Virtual Reality Modeling Language, virtual museum building and its effective interaction with the offline museum lie in making full use of 3 Dimensions panorama technique, virtual reality technique and augmented reality technique, and innovatively taking advantages of dynamic environment modeling technique, real-time 3 Dimensions graphics generating technique, system integration technique and other key virtual reality techniques to make sure the overall design of virtual museum.3 Dimensions panorama technique, also known as panoramic photography or virtual reality, is a technique based on static images of the reality. Virtual reality technique is a kind of computer simulation system which can create and experience the interactive 3 Dimensions dynamic visual world. Augmented reality, also known as mixed reality, is a technique which simulates and mixes the information (visual, sound, taste, touch, etc.) that is difficult for human to experience in reality. These technologies make virtual museum come true. It will not only bring better experience and convenience to the public, but also be conducive to improve the influence and cultural functions of the real museum.

  1. A specific closed percutaneous technique for reduction of Jeffery type II lesion.

    Science.gov (United States)

    Chotel, Franck; Sailhan, Frédéric; Martin, Jean-Noël; Filipe, Georges; Pem, Rajkumar; Garnier, Emmanuelle; Berard, Jerôme

    2006-09-01

    Open reduction is commonly recommended in Jeffery type II fractures. Attempts to reduce these fractures percutaneously were reported as unsafe and unreliable. We revisited this technique and used a specific percutaneous reduction that turned out to be successful in two cases. Instead of lifting the radial head as described in leverage maneuver, we use a pushing-back procedure to reduce the fracture. The maneuver aims at suppressing the capitellum interposition between the head fragment and the metaphysis by reproducing the reversed trajectory of trauma. This reduction is made possible because of the posterior periosteal attachment of the radial head. A few weeks after the procedure, the two patients remained painless, recovered a complete range of motion in prono-supination and returned to sports. In these two cases, the procedure used led to a prompt recovery and provided a much better outcome than described with the classic open approach.

  2. Possible fabrication techniques and welding specifications for the external cylinder of the CMS coil

    CERN Document Server

    Castoldi, M; Desirelli, Alberto; Favre, G; Losasso, M; Sequeira-Lopes-Tavares, S; Sgobba, Stefano; Tardy, T; Levesy, B; Reytier, M

    2000-01-01

    The Compact Muon Solenoid (CMS) is one of the experiments, which are being designed in the framework of the Large Hadron Collider (LHC) project at CERN. The design field of the CMS magnet is 4 T, the magnetic length is 12.5 m and the free aperture is 6 m in diameter. This is achieved with a 4 layer and 5 module superconducting Al- stabilized coil energized at a nominal current of 20 kA at 4.5 K. In the CMS coil the structural function is ensured, unlike in other existing Al-stabilized thin solenoids, both by the Al-alloy reinforced conductor and the external cylinder. The calculated stress level in the cylinder at operating conditions is particularly severe. In this paper the different possible fabrication techniques are assessed and compared and a possible welding specification for this component is given. (9 refs).

  3. Inspection Workshop-6: OSI Technologies: Methodologies and Techniques for Application

    Energy Technology Data Exchange (ETDEWEB)

    Krioutchenkov, V.; Shchukin, V.; Sweeney, J.J.

    2000-09-14

    On-Site Inspection (OSI) Workshop-6 met 26-30 June 2000 in Vienna, hosted by the Provisional Technical Secretariat (PTS) of the CTBT Organization. The purpose of the workshop was to provide guidance on OSI Operational Manual (OM) development for Working Group B (WGB) of the CTBT preparatory Commission (PrepCom) in the general areas of equipment and logistics. The two main sessions of this workshop, titled ''OSI Equipment: Development of Functional and Operational Requirements, Specifications and Application Procedures'' and ''OSI Logistics: Continued Work on Standing Arrangements, Status of Inspectors and Support Equipment Issues'' reflected this focus. For this workshop, the schedule of work was divided into two parts: The first half of the week were sessions with formal paper presentations and discussion; the latter half of the week used two smaller subgroups to focus on and discuss separately equipment and logistics issues. Drawing heavily on the results of the five previous workshops, these subgroups produced material to be considered by Working Group B. This provisional material is intended to advance the process of equipment definition and procurement and establish procedures for logistics that can be incorporated into the OSI Operational Manual. The participants agreed that using subgroups in this workshop was an especially effective mechanism for discussion of different expert opinion on technical issues, and that having access to material presented at the previous five OSI workshops was particularly valuable.

  4. The EDF catalogue of technical specifications (reference HN), standardization center; Catalogue des specifications techniques EDF (reference HN) centre de normalisation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    A list of EDF technical specifications, valid at the 01/01/1996 date, is presented. Specifications domains such as electrical installations, equipment and materials, uninsulated and insulated conductors, measurement, control and command, electric power generating or transforming equipment, electrical appliances, telecommunications, electronic and computer systems, are covered

  5. Application of nonlinear dynamic techniques to high pressure plasma jets

    Science.gov (United States)

    Ghorui, S.; Das, A. K.

    2010-02-01

    Arcs and arc plasmas have been known and used for welding, cutting, chemical synthesis and multitude of other industrial applications for more than hundred years. Though a copious source of heat, light and active species, plasma arc is inherently unstable, turbulent and difficult to control. During recent years, primarily driven by the need of new and energy efficient materials processing, various research groups around the world have been studying new and innovative ways of looking at the issues related to arc dynamics, arc stabilization, species non equilibrium, flow and heat transfer in a stabilized arc plasma device. In this context, experimental determination of nature of arc instabilities using tools of non-linear dynamics, theoretical model formulation, prediction of instability behavior under given operating conditions and possible control methods for the observed instabilities in arcs are reviewed. Space selective probing of the zones inside arc plasma devices without disturbing the system is probably the best way to identify the originating zone of instabilities inside such devices. Existence of extremely high temperature and inaccessibility to direct experimentations due to mechanical obstructions make this task extremely difficult. Probing instabilities in otherwise inaccessible inner regions of the torches, using binary gas mixture as plasma gas is a novel technique that primarily rests on a process known as demixing in arcs. Once a binary gas mixture enters the constricted plasma column, the demixing process sets in causing spatial variations for each of the constituent gases depending on the diffusion coefficients and the gradient of the existing temperature field. By varying concentrations of the constituent gases in the feeding line, it is possible to obtain spatial variations of the plasma composition in a desired manner, enabling spatial probing of the associated zones. Detailed compositional description of different zones inside the torch may be

  6. Application of integrated data mining techniques in stock market forecasting

    Directory of Open Access Journals (Sweden)

    Chin-Yin Huang

    2014-12-01

    Full Text Available Stock market is considered too uncertain to be predictable. Many individuals have developed methodologies or models to increase the probability of making a profit in their stock investment. The overall hit rates of these methodologies and models are generally too low to be practical for real-world application. One of the major reasons is the huge fluctuation of the market. Therefore, the current research focuses in the stock forecasting area is to improve the accuracy of stock trading forecast. This paper introduces a system that addresses the particular need. The system integrates various data mining techniques and supports the decision-making for stock trades. The proposed system embeds the top-down trading theory, artificial neural network theory, technical analysis, dynamic time series theory, and Bayesian probability theory. To experimentally examine the trading return of the presented system, two examples are studied. The first uses the Taiwan Semiconductor Manufacturing Company (TSMC data-set that covers an investment horizon of 240 trading days from 16 February 2011 to 23 January 2013. Eighty four transactions were made using the proposed approach and the investment return of the portfolio was 54% with an 80.4% hit rate during a 12-month period in which the TSMC stock price increased by 25% (from $NT 78.5 to $NT 101.5. The second example examines the stock data of Evergreen Marine Corporation, an international marine shipping company. Sixty four transactions were made and the investment return of the portfolio was 128% in 12 months. Given the remarkable investment returns in trading the example TSMC and Evergreen stocks, the proposed system demonstrates promising potentials as a viable tool for stock market forecasting.

  7. Split Hopkinson pressure bar technique: Experiments, analyses and applications

    Science.gov (United States)

    Gama, Bazle Anwer

    A critical review of the Hopkinson bar experimental technique is performed to identify the validity and applicability of the classic one-dimensional theory. A finite element model of the Hopkinson bar experiment is developed in three-dimensions and is used in detailed numerical analyses. For a small diameter hard specimen, the bar-specimen interfaces are non-planar, which predicts higher specimen strain and, thus, lower initial modulus in the linear elastic phase of deformation. In such cases, the stress distribution in the specimen is not uni-axial and a chamfered specimen geometry is found to provide better uni-axial stress condition in the specimen. In addition, a new Hopkinson bar with transmission tube is found suitable for small strain measurement of small diameter specimens. A one-dimensional exact Hopkinson bar theory considering the stress wave propagation in an equal diameter specimen has been formulated which predicts physically meaningful results in all extreme cases as compared to classic theory. In light of the theoretical and numerical investigations, an experimental methodology for rate dependent modulus and strength is developed. Quasi-static and dynamic behavior of plain weave (15 x 15) S-2 glass/SC15 composites has been investigated. A new circular-rectangular prism specimen (C-RPS) geometry is found suitable for testing laminated composites in the in-plane directions. Rate sensitive strength, non-linear strain and elastic modulus parameters for plain-weave (15 x 15) S-2 glass/SC15 composites have been experimentally determined.

  8. Application of techniques of biomechanics in the status evaluation and pathology correction of locomotor system

    Directory of Open Access Journals (Sweden)

    Romakina N.A.

    2015-09-01

    Full Text Available The article deals with the problem of development and the modern state of biomechanics as a scientific and practical direction in medicine under the context of technological advance herein a specific attention is paid to the achievements of the Russian schools. It is shown a necessity of wide usage of instrumental biomechanical diagnostics of locomotive disorders for intrinsic substantiation of rehabilitation treatment tactics and monitoring of its medical efficiency particularly for persons with remote effects of surgical interventions such as osteosynthesis, spondylosynthesis, total joint replacements. Non-invasive technique, possibility of its multiple application and rather low cost make actual using of locomotion clinical analysis techniques for rehabilitation treatment of concerned patients of different age groups.

  9. Open Knowledge Representation Techniques and Its Application in Precision Forming Design

    Directory of Open Access Journals (Sweden)

    Wang Ping

    2016-01-01

    Full Text Available Precision forming knowledge of precision forging parts can be acquired from various sources and generally requires an effective representation for its efficient reuse. According to the specific characteristics of the precision forming of car forging parts, the precision forming engineering knowledge has been classified into several kinds with the method of the open knowledge representation techniques for the different kinds of knowledge proposed. The open representation techniques of precision forming knowledge and its application are described in detail, and combined with the development of the precision forming design system of the automotive starter guiding cylinder based on knowledge. The results show that the precision forming knowledge is represented in an effective way will solve the problem of fusion of precision forming knowledge and precision forming manufacturing, and improve greatly the utilization efficiency of the precision forming knowledge.

  10. Application of learning techniques based on kernel methods for the fault diagnosis in industrial processes

    Directory of Open Access Journals (Sweden)

    Jose M. Bernal-de-Lázaro

    2016-05-01

    Full Text Available This article summarizes the main contributions of the PhD thesis titled: "Application of learning techniques based on kernel methods for the fault diagnosis in Industrial processes". This thesis focuses on the analysis and design of fault diagnosis systems (DDF based on historical data. Specifically this thesis provides: (1 new criteria for adjustment of the kernel methods used to select features with a high discriminative capacity for the fault diagnosis tasks, (2 a proposed approach process monitoring using statistical techniques multivariate that incorporates a reinforced information concerning to the dynamics of the Hotelling's T2 and SPE statistics, whose combination with kernel methods improves the detection of small-magnitude faults; (3 an robustness index to compare the diagnosis classifiers performance taking into account their insensitivity to possible noise and disturbance on historical data.

  11. Application of mass spectrometry-based proteomics techniques for the detection of protein doping in sports.

    Science.gov (United States)

    Kay, Richard G; Creaser, Colin S

    2010-04-01

    Mass spectrometry-based proteomic approaches have been used to develop methodologies capable of detecting the abuse of protein therapeutics such as recombinant human erythropoietin and recombinant human growth hormone. Existing detection methods use antibody-based approaches that, although effective, suffer from long assay development times and specificity issues. The application of liquid chromatography with tandem mass spectrometry and selected reaction-monitoring-based analysis has demonstrated the ability to detect and quantify existing protein therapeutics in plasma. Furthermore, the multiplexing capability of selected reaction-monitoring analysis has also aided in the detection of multiple downstream biomarkers in a single analysis, requiring less sample than existing immunological techniques. The flexibility of mass spectrometric instrumentation has shown that the technique is capable of detecting the abuse of novel and existing protein therapeutics, and has a vital role in the fight to keep sports drug-free.

  12. Specification and Verification of Web Applications in Rewriting Logic

    Science.gov (United States)

    Alpuente, María; Ballis, Demis; Romero, Daniel

    This paper presents a Rewriting Logic framework that formalizes the interactions between Web servers and Web browsers through a communicating protocol abstracting HTTP. The proposed framework includes a scripting language that is powerful enough to model the dynamics of complex Web applications by encompassing the main features of the most popular Web scripting languages (e.g. PHP, ASP, Java Servlets). We also provide a detailed characterization of browser actions (e.g. forward/backward navigation, page refresh, and new window/tab openings) via rewrite rules, and show how our models can be naturally model-checked by using the Linear Temporal Logic of Rewriting (LTLR), which is a Linear Temporal Logic specifically designed for model-checking rewrite theories. Our formalization is particularly suitable for verification purposes, since it allows one to perform in-depth analyses of many subtle aspects related to Web interaction. Finally, the framework has been completely implemented in Maude, and we report on some successful experiments that we conducted by using the Maude LTLR model-checker.

  13. Hardware-specific image compression techniques for the animation of CFD data

    Science.gov (United States)

    Jones, Stephen C.; Moorhead, Robert J., II

    1992-06-01

    The visualization and animation of computational fluid dynamics (CFD) data is vital in understanding the varied parameters that exist in the solution field. Scientists need accurate and efficient visualization techniques. The animation of CFD data is not only computationally expensive but also expensive in the allocation of memory, both RAM and disk. Preserving animations of the CFD data visualizations is useful, since recreation of the animation is expensive when dealing with extremely large data structures. Researchers of CFD data may wish to follow a particle trace over an experimental fuselage design, but are unable to retain the animation for efficient retrieval without rendering or consuming a considerable amount of disk space. The spatial image resolution is reduced from 1280 X 1024 to 512 X 480 in going from the workstation format to a video format, therefore, a desire to save these animations on disk results. Saving on disk allows the animation to maintain the spatial and intensity quality of the rendered image and allows the display of the animation at approximately 30 frames/sec, the standard video rate. The goal is to develop optimal image compression algorithms that allow visualization animations, captures as independent RGB images, to be recorded to tape or disk. If recorded to disk, the image sequence is compressed in non-realtime with a technique which allows subsequent decompression at approximately 30 frames/sec to simulate the temporal resolution of video. Initial compression is obtained through mapping RGB colors in each frame to a 12-bit colormap image. The colormap is animation sequence dependent and is created by histogramming the colors in the animation sequence and mapping those colors with relation to specific regions of the L*a*b* color coordinate system to take advantage of the uniform nature of the L*a*b* color system. Further compression is obtained by taking interframe differences, specifically comparing respective blocks between

  14. A brainwave signal measurement and data processing technique for daily life applications.

    Science.gov (United States)

    Yasui, Yoshitsugu

    2009-01-01

    A technique for measuring the psychophysiological status of the human and associated applications based on normal brain signals are examined and evaluated. A small single-point dry electrode developed for mobile use can capture brainwave activity from among dense external and internal electrical noise, and subsequently extract targeted frequency components. Continuous measurements during day and night provide a brainwave profile including wake and sleep states that can consistently explain states of human awareness. Statistical evaluation provides psychophysiological state change patterns which can be used to distinguish levels of alertness so as to prevent or avoid hazardous situations. We have taken a typical daily activity, namely, driving a car, to examine the applicability of our proposed method. Test results in terms of brain wave state show that the pattern while driving is changed by specific activity such as when talking on a mobile phone.

  15. 48 CFR 9904.405-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... cost accounting techniques which establishes and maintains adequate cost identification to permit audit... materiality, the Government and the contractor reach agreement on an alternate method that satisfies...

  16. Approximate calculational techniques for radiation protection applications (collection of papers presented at the November 1985 American Nuclear Society meeting)

    Energy Technology Data Exchange (ETDEWEB)

    Rice, A.F.; Roussin, R.W. (comps.)

    1986-09-01

    Although radiation protection principles are, on the whole, well understood and a whole series of computer codes exist for their solution, it is felt that there is a need for practical, approximate techniques to be used by the practicing nuclear engineer for a variety of applications. Within the context of approximate techniques, the papers presented cover a broad overview of specific problems, for example, skyshine and penetration analysis, with applications extending from general nuclear reactor design to spent fuel storage and fusion. Separate abstracts have been prepared for individual papers.

  17. Magnetic Resonance Microscopy Spatially Resolved NMR Techniques and Applications

    CERN Document Server

    Codd, Sarah

    2008-01-01

    This handbook and ready reference covers materials science applications as well as microfluidic, biomedical and dental applications and the monitoring of physicochemical processes. It includes the latest in hardware, methodology and applications of spatially resolved magnetic resonance, such as portable imaging and single-sided spectroscopy. For materials scientists, spectroscopists, chemists, physicists, and medicinal chemists.

  18. Application of image processing techniques for contrast enhancement in dense breast digital mammograms

    Science.gov (United States)

    Nunes, Fatima d. L. d. S.; Schiabel, Homero; Benatti, Rodrigo H.

    1999-05-01

    Dense breasts, that usually are characteristic of women less than 40 years old, difficult many times early detection of breast cancer. In this work we present the application of some image processing techniques intended to enhance the contrast in dense breast images, regarding the detection of clustered microcalcifications. The procedure was, firstly, determining in the literature the main techniques used for mammographic images contrast enhancement. The results indicate that, in general: (1) as expected, the overall performance of the CAD scheme for clusters detection decreased when applied exclusively to dense breast images, compared to the application to a set of images without this characteristic; (2) most of the techniques for contrast enhancement used successfully in generic mammography images databases are not able to enhance structures of athirst in databases formed only by dense breasts images, due to the very poor contrast between microcalcifications, for example, and other tissues. These features should stress, therefore, the need of developing a methodology specifically for this type of images in order to provide better conditions to the detection of breast suspicious structures in these group of women.

  19. 46 CFR 70.05-5 - Specific application noted in text.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Specific application noted in text. 70.05-5 Section 70... PROVISIONS Application § 70.05-5 Specific application noted in text. (a) At the beginning of the various... of the text involved. This application sets forth the types, sizes, or services or vessels to...

  20. 46 CFR 188.05-5 - Specific application noted in text.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Specific application noted in text. 188.05-5 Section 188... GENERAL PROVISIONS Application § 188.05-5 Specific application noted in text. (a) At the beginning of the... portion of the text involved. This application sets forth the types, sizes, or services or vessels...

  1. 46 CFR 90.05-5 - Specific application noted in text.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Specific application noted in text. 90.05-5 Section 90... VESSELS GENERAL PROVISIONS Application § 90.05-5 Specific application noted in text. (a) At the beginning... particular portion of the text involved. This application sets forth the types, sizes, or services or...

  2. Application of geoinformation techniques in sustainable development of marginal rural

    Science.gov (United States)

    Leszczynska, G.

    2009-04-01

    on location, properties of attributes and mutual relations of objects analyses of synergic influence of specific development forms on the environment and development of rural areas will be carried out. The important aspect here is the possibility of linking the phenomena and processes presented in maps with functional relations, including the space and time function. Application of that solution will allow analysis of actual marginal rural areas management system as a model of object and it will allow application of artificial intelligence as decision support tool. The system designed in that way will be characterized by the following properties: - it will be modelled and built of mutually communicating objects implemented by software using special object types. - division of the software into objects will facilitate its analysis. - dynamic properties of object structures: polymorphism, hermetization and implementation of methods in object structure will be applied. - objects will be used as the set of system model elements, which will assure ease of its modification. - specialization of classes will be introduced by means of inheritance of fields and methods [Muller, 2000]. The applied methods of object design coupled with GIS use should allow integration of marginal rural areas management according to the principle of sustainable development.

  3. The relevance vector machine technique for channel equalization application

    OpenAIRE

    Chen, S.; Gunn, S.R.; Harris, C J

    2001-01-01

    The recently introduced relevance vector machine (RVM) technique is applied to communication channel equalization. It is demonstrated that the RVM equalizer can closely match the optimal performance of the Bayesian equalizer, with a much sparser kernel representation than that is achievable by the state-of-art support vector machine (SVM) technique.

  4. Molecular biology techniques and applications for ocean sensing

    Science.gov (United States)

    Zehr, J. P.; Hewson, I.; Moisander, P.

    2009-05-01

    The study of marine microorganisms using molecular biological techniques is now widespread in the ocean sciences. These techniques target nucleic acids which record the evolutionary history of microbes, and encode for processes which are active in the ocean today. Molecular techniques can form the basis of remote instrumentation sensing technologies for marine microbial diversity and ecological function. Here we review some of the most commonly used molecular biological techniques. These techniques include the polymerase chain reaction (PCR) and reverse-transcriptase PCR, quantitative PCR, whole assemblage "fingerprinting" approaches (based on nucleic acid sequence or length heterogeneity), oligonucleotide microarrays, and high-throughput shotgun sequencing of whole genomes and gene transcripts, which can be used to answer biological, ecological, evolutionary and biogeochemical questions in the ocean sciences. Moreover, molecular biological approaches may be deployed on ocean sensor platforms and hold promise for tracking of organisms or processes of interest in near-real time.

  5. Two biased estimation techniques in linear regression: Application to aircraft

    Science.gov (United States)

    Klein, Vladislav

    1988-01-01

    Several ways for detection and assessment of collinearity in measured data are discussed. Because data collinearity usually results in poor least squares estimates, two estimation techniques which can limit a damaging effect of collinearity are presented. These two techniques, the principal components regression and mixed estimation, belong to a class of biased estimation techniques. Detection and assessment of data collinearity and the two biased estimation techniques are demonstrated in two examples using flight test data from longitudinal maneuvers of an experimental aircraft. The eigensystem analysis and parameter variance decomposition appeared to be a promising tool for collinearity evaluation. The biased estimators had far better accuracy than the results from the ordinary least squares technique.

  6. Molecular biology techniques and applications for ocean sensing

    Directory of Open Access Journals (Sweden)

    J. P. Zehr

    2008-11-01

    Full Text Available The study of marine microorganisms using molecular biological techniques is now widespread in the ocean sciences. These techniques target nucleic acids which record the evolutionary history of microbes, and encode for processes which are active in the ocean today. Here we review some of the most commonly used molecular biological techniques. Molecular biological techniques permit study of the abundance, distribution, diversity, and physiology of microorganisms in situ. These techniques include the polymerase chain reaction (PCR and reverse-transcriptase PCR, quantitative PCR, whole assemblage "fingerprinting" approaches (based on nucleic acid sequence or length heterogeneity, oligonucleotide microarrays, and high-throughput shotgun sequencing of whole genomes and gene transcripts, which can be used to answer biological, ecological, evolutionary and biogeochemical questions in the ocean sciences. Moreover, molecular biological approaches may be deployed on ocean sensor platforms and hold promise for tracking of organisms or processes of interest in near-real time.

  7. Molecular biology techniques and applications for ocean sensing

    Directory of Open Access Journals (Sweden)

    J. P. Zehr

    2009-05-01

    Full Text Available The study of marine microorganisms using molecular biological techniques is now widespread in the ocean sciences. These techniques target nucleic acids which record the evolutionary history of microbes, and encode for processes which are active in the ocean today. Molecular techniques can form the basis of remote instrumentation sensing technologies for marine microbial diversity and ecological function. Here we review some of the most commonly used molecular biological techniques. These techniques include the polymerase chain reaction (PCR and reverse-transcriptase PCR, quantitative PCR, whole assemblage "fingerprinting" approaches (based on nucleic acid sequence or length heterogeneity, oligonucleotide microarrays, and high-throughput shotgun sequencing of whole genomes and gene transcripts, which can be used to answer biological, ecological, evolutionary and biogeochemical questions in the ocean sciences. Moreover, molecular biological approaches may be deployed on ocean sensor platforms and hold promise for tracking of organisms or processes of interest in near-real time.

  8. 49 CFR 179.400 - General specification applicable to cryogenic liquid tank car tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false General specification applicable to cryogenic... MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specification for Cryogenic Liquid Tank Car Tanks and Seamless Steel Tanks (Classes DOT-113 and 107A) § 179.400 General specification applicable to cryogenic...

  9. Specification and testing of Multiplicative Time-Varying GARCH models with applications

    DEFF Research Database (Denmark)

    Amado, Cristina; Teräsvirta, Timo

    2017-01-01

    In this article, we develop a specification technique for building multiplicative time-varying GARCH models of Amado and Teräsvirta (2008, 2013). The variance is decomposed into an unconditional and a conditional component such that the unconditional variance component is allowed to evolve smoothly...... over time. This nonstationary component is defined as a linear combination of logistic transition functions with time as the transition variable. The appropriate number of transition functions is determined by a sequence of specification tests. For that purpose, a coherent modelling strategy based...... is illustrated in practice with two real examples: an empirical application to daily exchange rate returns and another one to daily coffee futures returns....

  10. Specifications and applications of the technical code for monitoring of building and bridge structures in China

    Directory of Open Access Journals (Sweden)

    Y Yang

    2016-12-01

    Full Text Available Recently, the exclusive compulsory technical code (GB 50982-2014 for structural health monitoring of buildings and bridges in China has been developed and implemented. This code covers the majority of the field monitoring methods and stipulates the corresponding technical parameters for monitoring of high-rise structures, large-span spatial structures, bridges and base-isolated structures. This article first presents the comprehensive review and linear comparison of existing structural health monitoring codes and standards. Subsequently, the progress of the codification of GB 50982-2014 is imparted and its main features and specifications are summarized. Finally, in accordance with GB50982-2014, several representative structural health monitoring practical applications of large-scale infrastructures in China are exemplified to illustrate how this national code can bridge the gap between theory and practical applications of structural health monitoring. This technical code is an important milestone in the application of well-established structural health monitoring techniques into the realistic and complex engineering projects. Also, it can provide abundant and authoritative information for practitioners and researchers involving the structural health monitoring techniques.

  11. Application of pattern recognition techniques to crime analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bender, C.F.; Cox, L.A. Jr.; Chappell, G.A.

    1976-08-15

    The initial goal was to evaluate the capabilities of current pattern recognition techniques when applied to existing computerized crime data. Performance was to be evaluated both in terms of the system's capability to predict crimes and to optimize police manpower allocation. A relation was sought to predict the crime's susceptibility to solution, based on knowledge of the crime type, location, time, etc. The preliminary results of this work are discussed. They indicate that automatic crime analysis involving pattern recognition techniques is feasible, and that efforts to determine optimum variables and techniques are warranted. 47 figures (RWR)

  12. Passive RF component technology materials, techniques, and applications

    CERN Document Server

    Wang, Guoan

    2012-01-01

    Focusing on novel materials and techniques, this pioneering volume provides you with a solid understanding of the design and fabrication of smart RF passive components. You find comprehensive details on LCP, metal materials, ferrite materials, nano materials, high aspect ratio enabled materials, green materials for RFID, and silicon micromachining techniques. Moreover, this practical book offers expert guidance on how to apply these materials and techniques to design a wide range of cutting-edge RF passive components, from MEMS switch based tunable passives and 3D passives, to metamaterial-bas

  13. Pilot Application of a Teaching Technique in Social Medicine

    Science.gov (United States)

    Wegman, David H.; and others

    1969-01-01

    Using techniques that combine community health services with a learning situation, Boston area medical students interviewed people within a community to determine whether existing medical facilities meet or fail to meet their health needs. (LP)

  14. Application of Molecular Diagnostic Techniques for Viral Testing

    OpenAIRE

    Cobo, Fernando

    2012-01-01

    Nucleic acid amplification techniques are commonly used currently to diagnose viral diseases and manage patients with this kind of illnesses. These techniques have had a rapid but unconventional route of development during the last 30 years, with the discovery and introduction of several assays in clinical diagnosis. The increase in the number of commercially available methods has facilitated the use of this technology in the majority of laboratories worldwide. This technology has reduced the...

  15. Study and application of X radiation sampling technique

    Institute of Scientific and Technical Information of China (English)

    葛良全; 章晔; 等

    1996-01-01

    The physical bases of a X radiation sampling technique are investigated.Three technical problems of unevenness,matrix and heterogeneous mineralization effects,are considered and successfully resolved.This new technique was appled to three sites of Au,Sn and Cu deposits(representing higher,medial and lower atomic number minerals)in different exploration stages in China and satisfactory results are obtained.

  16. Clinical Application of Movement-needling Technique: Stiff Neck

    Institute of Scientific and Technical Information of China (English)

    LIU Yan

    2005-01-01

    @@ Movement-needling Technique, a new acupuncture therapy, is based on traditional acupuncture therapy and anatomical principle, combining acupuncture and movement. Combining disease and syndrome differentiation, and integrating TCM and Western medical diagnosis, this technique is used to treat different diseases mainly with acupuncture,combining some movement in needling. These movements not only boost therapeutic effects of acupuncture, but also add new contents to traditional acupuncture.

  17. Chemical dosimetry techniques for various applications under different geometries

    CERN Document Server

    Gupta, B L; Narayan, G R; Nilekani, S R

    2000-01-01

    This paper gives the results of dosimetry for various applications under different geometrical arrangements. These applications include: gamma chambers, blood irradiators, radiotherapy using both sup 6 sup 0 Co and accelerators, animal irradiations with different types of radiation sources, fluid irradiators for sludge and rubber latex and industrial electron irradiators. The dosimeters used were Fricke, FBX and alanine/glutamine (spectrophotometric readout).

  18. A study on nuclear specific material detection technique using nuclear resonance reactions

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Y. K.; Ha, J. H.; Cho, Y. S.; Choi, B. H. [KAERI, Taejon (Korea, Republic of)

    2001-10-01

    The non-destructive nuclear material detection technique is one of the novel methods under somewhat dangerous environments, for example, high level radiation or landmine areas. Specially, the detection of a landmine is a hot issue on the peaceful use of nuclear technology for human welfare. Generally, the explosives contain specific elements such as {sup 14}N or {sup 35}Cl. The photo-nuclear resonance gamma-rays are produced by nuclear reaction {sup 13}C(p , {gamma}){sup 14}N or {sup 34}S(p, {gamma}){sup 35}Cl in which target is bombarded by about 2MeV proton beam extracted from the proton accelerator. To avoid other neighboring resonant gamma-rays, we selected a higher resonant energy above 5MeV. The resonance gamma rays produced are absorbed or scattered when they react with {sup 14}N or {sup 35}Cl included in the mines and explosive. We can determine existence and position of mines or explosives by detecting the absorption and scattering gamma-ray signals.

  19. Building Domain Specific Languages for Voice Recognition Applications

    Directory of Open Access Journals (Sweden)

    Cristian IONITA

    2008-01-01

    Full Text Available This paper presents a method of implementing the voice recognition for the control of software applications. The solutions proposed are based on transforming a subset of the natural language in commands recognized by the application using a formal language defined by the means of a context free grammar. At the end of the paper is presented the modality of integration of voice recognition and of voice synthesis for the Romanian language in Windows applications.

  20. The impact of the salting-out technique on the preparation of colloidal particulate systems for pharmaceutical applications.

    Science.gov (United States)

    Mendoza-Muñoz, Néstor; Quintanar-Guerrero, David; Allémann, Eric

    2012-12-01

    The recent advances in nanotechnology and its application in medicine have merged into a new concept called nanomedicine. Colloidal drug delivery systems and specifically polymeric nanoparticles are one of the most promising novel drug carriers due to their capacity for passive or active targeting for therapeutic and diagnostic applications. The introduction of novel therapeutic nanoscaled agents requires simple, efficient and feasible industrial-scale production methods. Biodegradable polymeric nanoparticles are usually prepared from preformed polymers by five techniques: emulsification- solvent evaporation, solvent displacement, salting-out, emulsification-solvent diffusion and double emulsion solvent evaporation. This review discusses the use of the salting-out technique for the preparation of nanoparticles in the development of systems for drug delivery and other pharmaceutical applications. The relevant applications, formulations and release characteristics of novel colloidal drug delivery preparations from research literature and patents are summarized. This review is intended as a tool for the rational development of polymeric colloidal systems for pharmaceutical use.

  1. Application-specific mesh-based heterogeneous FPGA architectures

    CERN Document Server

    Parvez, Husain

    2011-01-01

    This volume presents a new exploration environment for mesh-based, heterogeneous FPGA architectures. Readers will find a description of state-of-the-art techniques for reducing area requirements, which both increase performance and enable power reduction.

  2. Application of predictive modelling techniques in industry: from food design up to risk assessment.

    Science.gov (United States)

    Membré, Jeanne-Marie; Lambert, Ronald J W

    2008-11-30

    In this communication, examples of applications of predictive microbiology in industrial contexts (i.e. Nestlé and Unilever) are presented which cover a range of applications in food safety from formulation and process design to consumer safety risk assessment. A tailor-made, private expert system, developed to support safe product/process design assessment is introduced as an example of how predictive models can be deployed for use by non-experts. Its use in conjunction with other tools and software available in the public domain is discussed. Specific applications of predictive microbiology techniques are presented relating to investigations of either growth or limits to growth with respect to product formulation or process conditions. An example of a probabilistic exposure assessment model for chilled food application is provided and its potential added value as a food safety management tool in an industrial context is weighed against its disadvantages. The role of predictive microbiology in the suite of tools available to food industry and some of its advantages and constraints are discussed.

  3. Sequential specification of time-aware stream processing applications

    NARCIS (Netherlands)

    Geuns, Stefan J.; Hausmans, Joost P.H.M.; Bekooij, Marco J.G.

    2013-01-01

    Automatic parallelization of Nested Loop Programs (NLPs) is an attractive method to create embedded real-time stream processing applications for multi-core systems. However, the description and parallelization of applications with a time dependent functional behavior has not been considered in NLPs.

  4. Model order reduction techniques with applications in finite element analysis

    CERN Document Server

    Qu, Zu-Qing

    2004-01-01

    Despite the continued rapid advance in computing speed and memory the increase in the complexity of models used by engineers persists in outpacing them. Even where there is access to the latest hardware, simulations are often extremely computationally intensive and time-consuming when full-blown models are under consideration. The need to reduce the computational cost involved when dealing with high-order/many-degree-of-freedom models can be offset by adroit computation. In this light, model-reduction methods have become a major goal of simulation and modeling research. Model reduction can also ameliorate problems in the correlation of widely used finite-element analyses and test analysis models produced by excessive system complexity. Model Order Reduction Techniques explains and compares such methods focusing mainly on recent work in dynamic condensation techniques: - Compares the effectiveness of static, exact, dynamic, SEREP and iterative-dynamic condensation techniques in producing valid reduced-order mo...

  5. Applications of predictive maintenance techniques in industrial systems

    Directory of Open Access Journals (Sweden)

    Marjanović Aleksandra

    2011-01-01

    Full Text Available Prognostic methods represent a new methodology for system maintenance which offers significant time and cost savings. The paper offers a short overview of the available prognosis techniques and proposes the implementation of one model-based and one data-driven method. As a representative of the model-based methods the autoregressive moving average (ARMA modeling approach is chosen. The estimated model parameters are further used for implementing the early change detector which is realized as a Neyman-Pearson hypothesis test. On the other hand, hidden Markov model (HMM based prognosis illustrates the use of data-driven techniques. Using the cross-correlation input-output functions, HMM prognosis algorithm is proposed, as a suitable way of timely detection. Both techniques were implemented to detect performance changes of the water level sensor in a steam separator system in thermal power plants.

  6. Catalytic Methods in Asymmetric Synthesis Advanced Materials, Techniques, and Applications

    CERN Document Server

    Gruttadauria, Michelangelo

    2011-01-01

    This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milesto

  7. Techniques for Performance Improvement of Integer Multiplication in Cryptographic Applications

    Directory of Open Access Journals (Sweden)

    Robert Brumnik

    2014-01-01

    Full Text Available The problem of arithmetic operations performance in number fields is actively researched by many scientists, as evidenced by significant publications in this field. In this work, we offer some techniques to increase performance of software implementation of finite field multiplication algorithm, for both 32-bit and 64-bit platforms. The developed technique, called “delayed carry mechanism,” allows to preventing necessity to consider a significant bit carry at each iteration of the sum accumulation loop. This mechanism enables reducing the total number of additions and applies the modern parallelization technologies effectively.

  8. Chinese chart publishing data updating technique and application

    Science.gov (United States)

    Liu, G. H.; Peng, R. C.; Chen, Y.; Gao, W. J.; Guo, L. X.; Zheng, Y. D.

    2007-06-01

    Although the production of nautical chart has developed a lot in China, there are still some defects, such as the long period of producing nautical chart, the continuous correction to the nautical chart published, and so on. On basis of analyzing Chinese chart publishing data and its updating data, this paper researches on the technique of interactively updating server chart publishing data and the technique of automatically updating client chart publishing data, which will lay the foundation for constructing the mode of printing charts on demand in China.

  9. Applications of Indirect Imaging techniques in X-ray binaries

    CERN Document Server

    Harlaftis, E T

    2000-01-01

    A review is given on aspects of indirect imaging techniques in X-ray binaries which are used as diagnostics tools for probing the X-ray dominated accretion disc physics. These techniques utilize observed properties such as the emission line profile variability, the time delays between simultaneous optical/X-ray light curves curves, the light curves of eclipsing systems and the pulsed emission from the compact object in order to reconstruct the accretion disc's line emissivity (Doppler tomography), the irradiated disc and heated secondary (echo mapping), the outer disc structure (modified eclipse mapping) and the accreting regions onto the compact object, respectively.

  10. Strategies in the application of the Donnan membrane technique.

    NARCIS (Netherlands)

    Weng, L.P.; Vega, F.A.; Riemsdijk, van W.H.

    2011-01-01

    e Donnan membrane technique (DMT) can be applied to measure free ion concentrations both in laboratory and in situ in the field. In designing DMT experiments, different strategies can be taken, depending on whether accumulation is needed. (1) When the free ion concentration is above the detection li

  11. Application of multileaf collimator in breast cancer radiation techniques

    Science.gov (United States)

    Janiszewska, Marzena; Dupla, Dorota; Nowakowski, Grzegorz

    2004-07-01

    Modern radiation therapy tools allow a precise delivery of a high dose to a target area (so-called planning target volume -- PTV) and spare, at the same time, critical organs in the vicinity of cancerous lesions. One of the tools of conformal therapy is a multi-leaf collimator, which provides the opportunity to optimally adjust the therapeutic field to the tumor area. More difficult areas for radiation therapy include: mamma, after BCT, and chest after mammectomy with regional lymph nodes. The objective of the study is to present technical and physical aspects of breast carcinoma irradiation when applying a multi-leaf collimator. The following techniques were applied: (a) the isocentric technique of tangent fields (from two to four) for the mamma after BCT; (b) the method of a common isocenter, for the areas of mamma and for regional lymph nodes; (c) the technique of complementary photon + electron fields, for the area of chest after mammectomy and lymph nodes. The presented techniques were implemented as standard procedures in the preparation of breast carcinoma radiation treatment in the Lower Silesian Oncology Center.

  12. Electronics system design techniques for safety critical applications

    CERN Document Server

    Sterpone, Luca

    2008-01-01

    Addresses the development of techniques for the evaluation and the hardening of designs implemented on SRAM-based Field Programmable Gate Arrays. This title presents a design methodology solving industrial designer''s needs for implementing electronic systems using SRAM-based FPGAs in critical environments, like the space or avionic ones.

  13. 48 CFR 9905.506-50 - Techniques for application.

    Science.gov (United States)

    2010-10-01

    ... transitional cost accounting period is required under the provisions of 9905.506-40(a)(3), the institution may.... 9905.506-50 Section 9905.506-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS FOR EDUCATIONAL INSTITUTIONS 9905.506-50 Techniques...

  14. Secure image transform domain technique for steganographic applications

    Science.gov (United States)

    Alturki, Faisal T.; Mersereau, Russell M.

    2001-08-01

    Digital steganography is the art of secretly hiding information inside a multimedia signal in such a way that its very existence is concealed. In this paper, we present a new steganographic technique for covert communications. The technique embeds the hidden information in the transform domain after decorrelating the image samples in the spatial domain using a key. This results in a significant increase in the number of transform coefficients that can be used to transmit the hidden information, and therefore, increases the data embedding capacity. The hidden information is embedded in the transform domain after taking a block DCT of the decorrelated image. A quantization technique is used to embed the hidden data. The decoding process requires the availability of the same key that was used to decorrelate the image samples. By using quantization techniques, the hidden information can be recovered reliably. If the key is not available at the decoder it is impossible to recover the hidden information. Hence, this system is secure against removal attacks. The statistical properties of the cover and the stego image remain identical for small quantization steps. Therefore, the hidden data cannot be detected. The data embedding system is modeled as transmitting information through a Gaussian channel.

  15. The Applicability of Lean and Six Sigma Techniques to Clinical and Translational Research

    Science.gov (United States)

    Schweikhart, Sharon A.; Dembe, Allard E

    2010-01-01

    Background Lean and Six Sigma are business management strategies commonly used in production industries to improve process efficiency and quality. During the past decade, these process improvement techniques increasingly have been applied outside of the manufacturing sector, for example, in health care and in software development. This article concerns the potential use of Lean and Six Sigma to improve the processes involved in clinical and translational research. Improving quality, avoiding delays and errors, and speeding up the time to implementation of biomedical discoveries are prime objectives of the NIH Roadmap for Biomedical Research and the NIH Clinical and Translational Science Award (CTSA) program. Methods This article presents a description of the main principles, practices, and methodologies used in Lean and Six Sigma. Available literature involving applications of Lean and Six Sigma to health care, laboratory science, and clinical and translational research is reviewed. Specific issues concerning the use of these techniques in different phases of translational research are identified. Results Examples are provided of Lean and Six Sigma applications that are being planned at a current CTSA site, which could potentially be replicated elsewhere. We describe how different process improvement approaches are best adapted for particularly translational research phases. Conclusions Lean and Six Sigma process improvement methodologies are well suited to help achieve NIH’s goal of making clinical and translational research more efficient and cost-effective, enhancing the quality of the research, and facilitating the successful adoption of biomedical research findings into practice. PMID:19730130

  16. The applicability of Lean and Six Sigma techniques to clinical and translational research.

    Science.gov (United States)

    Schweikhart, Sharon A; Dembe, Allard E

    2009-10-01

    Lean and Six Sigma are business management strategies commonly used in production industries to improve process efficiency and quality. During the past decade, these process improvement techniques increasingly have been applied outside the manufacturing sector, for example, in health care and in software development. This article concerns the potential use of Lean and Six Sigma in improving the processes involved in clinical and translational research. Improving quality, avoiding delays and errors, and speeding up the time to implementation of biomedical discoveries are prime objectives of the National Institutes of Health (NIH) Roadmap for Medical Research and the NIH's Clinical and Translational Science Award program. This article presents a description of the main principles, practices, and methods used in Lean and Six Sigma. Available literature involving applications of Lean and Six Sigma to health care, laboratory science, and clinical and translational research is reviewed. Specific issues concerning the use of these techniques in different phases of translational research are identified. Examples of Lean and Six Sigma applications that are being planned at a current Clinical and Translational Science Award site are provided, which could potentially be replicated elsewhere. We describe how different process improvement approaches are best adapted for particular translational research phases. Lean and Six Sigma process improvement methods are well suited to help achieve NIH's goal of making clinical and translational research more efficient and cost-effective, enhancing the quality of the research, and facilitating the successful adoption of biomedical research findings into practice.

  17. Grazing impact of microzooplankton on phytoplankton in the Xiamen Bay using pigment-specific dilution technique

    Institute of Scientific and Technical Information of China (English)

    HUANG Bangqin; LIU Yuan; XIANG Weiguo; TIAN Haojie; LIU Hongbin; CAO Zhenrui; HONG Huasheng

    2008-01-01

    Phytoplankton group-specific growth and microzooplankton grazing were determined seasonally using the dilution technique with high-performance liquid chromatography (HPLC) in the Xiamen Bay, a subtropical bay in southeast China, between May 2003 and February 2004. The results showed that growth rates of phytoplankton ranged from 0.71 to 2.2 d -1 with the highest value occurred in the inner bay in May. Microzooplankton grazing rates ranged from 0.5 to 3.1 d-1 with the highest value occurred in the inner bay in August. Microzooplankton grazing impact ranged from 39% to 95% on total phytoplankton Chl a biomass, and 65% to 181% on primary production. The growth and grazing rates of each phytoplankton group varied, the highest growth rate (up to 3.3 d -1 ) was recorded for diatoms in August, while the maximum grazing rate ( up to 2.1 d -1 ) was recorded for chlorophytes in February in the inner bay. Among main phytoplankton groups, grazing pressure of microzooplankton ranged from 10% to 83% on Chl a biomass, and from 14% to 151% on primary production. The highest grazing pressure on biomass was observed for cryptophytes (83%) in August, while the maximum grazing pressure on primary production was observed for cyanobacteria (up to 151% ) in December in the inner bay. Net growth rates of larger phytoplanktons (diatoms and dinoflagellates) were higher than those of smaller groups (prasinophytes, chlorophytes and cyanobacteria). Relative preference index showed that microzooplankton grazed preferentially on prasinophytes and avoided to harvest diatoms in cold seasons ( December and February).

  18. A tri-gram based feature extraction technique using linear probabilities of position specific scoring matrix for protein fold recognition.

    Science.gov (United States)

    Paliwal, Kuldip K; Sharma, Alok; Lyons, James; Dehzangi, Abdollah

    2014-03-01

    In biological sciences, the deciphering of a three dimensional structure of a protein sequence is considered to be an important and challenging task. The identification of protein folds from primary protein sequences is an intermediate step in discovering the three dimensional structure of a protein. This can be done by utilizing feature extraction technique to accurately extract all the relevant information followed by employing a suitable classifier to label an unknown protein. In the past, several feature extraction techniques have been developed but with limited recognition accuracy only. In this study, we have developed a feature extraction technique based on tri-grams computed directly from Position Specific Scoring Matrices. The effectiveness of the feature extraction technique has been shown on two benchmark datasets. The proposed technique exhibits up to 4.4% improvement in protein fold recognition accuracy compared to the state-of-the-art feature extraction techniques.

  19. Stereomask lithography (SML): a universal multi-object micro-patterning technique for biological applications.

    Science.gov (United States)

    Zhao, Siwei; Chen, Arnold; Revzin, Alexander; Pan, Tingrui

    2011-01-21

    The advent of biological micro-patterning techniques has given new impetus to many areas of biological research, including quantitative biochemical analysis, tissue engineering, biosensing, and regenerative medicine. Derived from photolithography or soft lithography, current bio-patterning approaches have yet to completely address the needs of out-of-cleanroom, universal applicability, high feature resolution, as well as multi-object placement, though many have shown great promise to precisely pattern one specific biomaterial. In this paper, we present a novel versatile biological lithography technique to achieve integrated multi-object patterning with high feature resolution and high adaptability to various biomaterials, referred to as stereomask lithography (SML). Successive patterning of multiple objects is enabled by using unique three-dimensional masks (i.e., the stereomasks), which lay out current micropatterns while protecting pre-existing biological features on the substrate. Furthermore, high-precision reversible alignment among multiple bio-objects is achieved by adopting a peg-in-hole design between the substrate and stereomasks. We demonstrate that the SML technique is capable of constructing a complex biological microenvironment with various bio-functional components at the single-cell resolution, which to the best of our knowledge has not been realized before.

  20. Apt strain measurement technique for impulsive loading applications

    Science.gov (United States)

    Ranjan Nanda, Soumya; Kulkarni, Vinayak; Sahoo, Niranjan

    2017-03-01

    The necessity of precise measurement of strain time history for impulsive loading applications has been addressed in the present investigation. Finite element modeling is initially carried out for a hemispherical test model and stress bar assembly to arrive at an appropriate location for strain measurement. In dynamic calibration experiments, strain measurements are performed using two wire and three wire quarter bride arrangements along with half bridge circuit. Usefulness of these arrangements has been verified by analyzing strain signals in time and frequency domains. Comparison of recovered force time histories proved that the half bridge circuit is the most suitable for such applications. Actual shock tube testing of the instrumented hemispherical test model confirmed the applicability of half bridge circuit for short duration strain measurements.

  1. Techniques of EMG signal analysis: detection, processing, classification and applications

    Science.gov (United States)

    Hussain, M.S.; Mohd-Yasin, F.

    2006-01-01

    Electromyography (EMG) signals can be used for clinical/biomedical applications, Evolvable Hardware Chip (EHW) development, and modern human computer interaction. EMG signals acquired from muscles require advanced methods for detection, decomposition, processing, and classification. The purpose of this paper is to illustrate the various methodologies and algorithms for EMG signal analysis to provide efficient and effective ways of understanding the signal and its nature. We further point up some of the hardware implementations using EMG focusing on applications related to prosthetic hand control, grasp recognition, and human computer interaction. A comparison study is also given to show performance of various EMG signal analysis methods. This paper provides researchers a good understanding of EMG signal and its analysis procedures. This knowledge will help them develop more powerful, flexible, and efficient applications. PMID:16799694

  2. Application Specific Chemical Information Microprocessor (ASCI mu P)

    Science.gov (United States)

    2016-06-13

    techniques. These channels, 100 microns wide, were etched to a depth of about 10 microns. A cover plate with holes drilled into the glass, needed for...mode of the CE device. First, we have modified the initial design seen in Figure 1 to incorporate a three- metal electrode detection arrangement at the

  3. Nightmares in crisis: clinical applications of lucid dreaming techniques.

    Science.gov (United States)

    Brylowski, A

    1990-06-01

    A patient in crisis was offered treatment with a major focus on alleviating nightmares using lucid dreaming (dreaming while knowing that one is dreaming). Of sixty-eight non-psychotic patients seen consecutively in a psychiatry emergency room, she was one of 16 (23.5%) found to have a concurrent complaint of nightmares (dream anxiety disorder). The benefits of the skills developed with lucid dreaming extended into areas other than nightmares as the patient entered psychotherapy. The techniques appeared to play a role in the reduction of nightmare frequency, intensity, and distress, and to enhance ego growth and personal development. Further research in lucid dreaming as an adjunctive treatment for patients with nightmares and as a useful technique in psychotherapy is suggested.

  4. Different Applications of Rheological Techniques in Studies of Physical Gels

    DEFF Research Database (Denmark)

    Hvidt, Søren

    . Rheological techniques are used extensively in studies of physical gels and gelation. In the lecture some of the common techniques used in studies of gels will be addressed. Small amplitude oscillatory measurements are the most common type of measurement performed, and such measurements allow a determination......Physical gels are of both great scientific and practical interest. The cytoplasm of cells, which consists of a complex physical gel of protein filaments, is important for most of the cellular processes including cell division and cell motility. Nature has developed this complex system......-forming biopolymers. Physical gels are also used in the paint industry to minimize sedimentation. Delayed and controlled drug release is of importance in the pharmaceutical industry, and one way to obtain this control is to hide active components in physical gels. Two excellent reviews cover many aspects...

  5. MR enterography in children: Principles, technique, and clinical applications

    Directory of Open Access Journals (Sweden)

    Govind B Chavhan

    2013-01-01

    Full Text Available MR enterography is a constantly advancing technique for assessment of bowel with newer technology and sequences. It is being increasingly used for the assessment of inflammatory bowel disease and has almost replaced barium follow through examinations in many institutions. Its lack of radiation makes it an attractive alternative for bowel evaluation in children. It has been proved to be highly sensitive in the detection of Crohn disease in adults and children. It is also superior to barium studies in showing extra-enteric findings and detecting complications such as fistulas and abscesses. Even though at present it is almost exclusively used for the evaluation of inflammatory bowel disease, it has the potential to be used in other conditions affecting the bowel. The principles, MR enterography technique pertinent to children, and its utility in the assessment of Crohn disease in children are discussed in this review.

  6. Application of Sensing Techniques to Cellular Force Measurement

    Directory of Open Access Journals (Sweden)

    James H.-C. Wang

    2010-11-01

    Full Text Available Cell traction forces (CTFs are the forces produced by cells and exerted on extracellular matrix or an underlying substrate. CTFs function to maintain cell shape, enable cell migration, and generate and detect mechanical signals. As such, they play a vital role in many fundamental biological processes, including angiogenesis, inflammation, and wound healing. Therefore, a close examination of CTFs can enable better understanding of the cellular and molecular mechanisms of such processes. To this end, various force-sensing techniques for CTF measurement have been developed over the years. This article will provide a concise review of these sensing techniques and comment on the needs for improved force-sensing technologies for cell mechanics and biology research.

  7. On the selection of dimension reduction techniques for scientific applications

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Y J; Kamath, C

    2012-02-17

    Many dimension reduction methods have been proposed to discover the intrinsic, lower dimensional structure of a high-dimensional dataset. However, determining critical features in datasets that consist of a large number of features is still a challenge. In this paper, through a series of carefully designed experiments on real-world datasets, we investigate the performance of different dimension reduction techniques, ranging from feature subset selection to methods that transform the features into a lower dimensional space. We also discuss methods that calculate the intrinsic dimensionality of a dataset in order to understand the reduced dimension. Using several evaluation strategies, we show how these different methods can provide useful insights into the data. These comparisons enable us to provide guidance to a user on the selection of a technique for their dataset.

  8. Case report macroglossia: Review and application of tongue reduction technique

    Directory of Open Access Journals (Sweden)

    Bilommi R. Irhamni

    2015-05-01

    Full Text Available Congenital macroglossia is uncommon condition, Enlargement can be true as seen in vascular malformations or muscular enlargement. It may cause significant symptoms in children such as sleep apnea, respiratory distress, drooling, difficulty in swallowing and dysarthria. Long-standing macroglossia leads to an anterior open bite deformity, mucosal changes, exposure to potential trauma, increased incidence of upper respiratory tract infections and failure to thrive. Tongue movements, sounds and Speech articulation may also be affected. It is important to achieve uniform global reduction of the enlarged tongue for functional as well as esthetic reasons. The multiple techniques advocated for tongue reduction reveal that an ideal procedure has yet to emerge. In our case report we describe a modified reduction technique of the tongue globally preserving the taste, sensation and mobility of the tongue suitable for cases of enlargement of the tongue as in muscular hypertrophy. It can be used for repeat reductions without jeopardizing the mobility and sensibility of the tongue.

  9. Application of neutron activation tracer sediment technique on environmental science

    Institute of Scientific and Technical Information of China (English)

    YinYi; ZhongWei-Ni; 等

    1997-01-01

    Field and laboratory inverstigations were carried out to study the transport and dispersion law of polluted sediments near wastewater outlet using neutron activation tracer technique.The direction of transport and dispersion of polluted sediments,dispersion amount in different directions,sedimentary region of polluted sediment and evaluation of polluted risk are given.This provided a new test method for the study of environmental science and added a new forecasted content for the evaluation of environmental influence.

  10. Application of Grammatical Parsing Technique in Chinese Input

    Institute of Scientific and Technical Information of China (English)

    俞士汶

    1990-01-01

    In Peking University Computer Research Institute(PUCRI) a method of inputting Chinese sentences based on words has been developed.To reduce the troubles in choosing one word out of the others characterized by the same feature,grammatical parsing technique is applied to the method and good results have been achieved.This article describes the outline of the method.the principle of applying grammatical formulas and the branch-cutting algorithm used to speed up the grammatical parsing.

  11. Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications

    Science.gov (United States)

    Pepin, Kay M.; Ehman, Richard L.; McGee, Kiaran P.

    2015-01-01

    Tissue mechanical properties are significantly altered with the development of cancer. Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying tissue mechanical properties in vivo. This review describes the basic principles of MRE and introduces some of the many promising MRE methods that have been developed for the detection and characterization of cancer, evaluation of response to therapy, and investigation of the underlying mechanical mechanisms associated with malignancy. PMID:26592944

  12. Modern machine learning techniques and their applications in cartoon animation research

    CERN Document Server

    Yu, Jun

    2013-01-01

    The integration of machine learning techniques and cartoon animation research is fast becoming a hot topic. This book helps readers learn the latest machine learning techniques, including patch alignment framework; spectral clustering, graph cuts, and convex relaxation; ensemble manifold learning; multiple kernel learning; multiview subspace learning; and multiview distance metric learning. It then presents the applications of these modern machine learning techniques in cartoon animation research. With these techniques, users can efficiently utilize the cartoon materials to generate animations

  13. Moire Ct technique and its application on laser flexible manufacture

    Science.gov (United States)

    Li, Tianze; Hou, Luan; Jiang, Chuan; Zhang, Xia

    2010-10-01

    In the paper, the main properties of Moire fringe, such as average effect, amplification effect, corresponding relation are elaborated, and the principle of Moire Ct technique is represented. On the basis of main features of Moire fringe, multidirectional Moire Ct deflection system is designed using high accuracy Ccd, grating, filter, lens, planar mirror and optical splitter. The system has simple light path, and can be easily made into the one that has large caliber.It can analyze multidirectional records of the probe at the same time, and can obtain clear interference patterns.The iterative technique combined with computer chromatography algorithms is used to achieve inversion of multidirectional clear interference patterns so that the required parameters can be acquired. Moire Ct technique is applied to laser flexible manufacture. Produced parts are delaminated on the paper, and are stratified manufactured until they are connected to forming. Cad/Cam system is adopted to construct Spatial three-dimensional geometric model, and the data files are formed. Then by using the Small triangle plane, the inner and outer surfaces of the data files are discretized. Discretized parts model is made chromatography with mathematical methods using Cam software. A series of parallel horizontal intersecting planes are generated. The problems of filtering arrangement tangent points are solved by recombining the shape and structure relationship among the triangular mesh. Several conclusions are presented.

  14. Application of physical and chemical characterization techniques to metallic powders

    Energy Technology Data Exchange (ETDEWEB)

    Slotwinski, J. A. [Intelligent Systems Division, Engineering Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899 (United States); Watson, S. S.; Stutzman, P. E.; Ferraris, C. F.; Peltz, M. A.; Garboczi, E. J. [Materials and Structural Systems Division, Engineering Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899 (United States)

    2014-02-18

    Systematic studies have been carried out on two different powder materials used for additive manufacturing: stainless steel and cobalt-chrome. The characterization of these powders is important in NIST efforts to develop appropriate measurements and standards for additive materials and to document the property of powders used in a NIST-led additive manufacturing material round robin. An extensive array of characterization techniques was applied to these two powders, in both virgin and recycled states. The physical techniques included laser diffraction particle size analysis, X-ray computed tomography for size and shape analysis, and optical and scanning electron microscopy. Techniques sensitive to chemistry, including X-ray diffraction and energy dispersive analytical X-ray analysis using the X-rays generated during scanning electron microscopy, were also employed. Results of these analyses will be used to shed light on the question: how does virgin powder change after being exposed to and recycled from one or more additive manufacturing build cycles? In addition, these findings can give insight into the actual additive manufacturing process.

  15. Application of multivariate statistical techniques in microbial ecology.

    Science.gov (United States)

    Paliy, O; Shankar, V

    2016-03-01

    Recent advances in high-throughput methods of molecular analyses have led to an explosion of studies generating large-scale ecological data sets. In particular, noticeable effect has been attained in the field of microbial ecology, where new experimental approaches provided in-depth assessments of the composition, functions and dynamic changes of complex microbial communities. Because even a single high-throughput experiment produces large amount of data, powerful statistical techniques of multivariate analysis are well suited to analyse and interpret these data sets. Many different multivariate techniques are available, and often it is not clear which method should be applied to a particular data set. In this review, we describe and compare the most widely used multivariate statistical techniques including exploratory, interpretive and discriminatory procedures. We consider several important limitations and assumptions of these methods, and we present examples of how these approaches have been utilized in recent studies to provide insight into the ecology of the microbial world. Finally, we offer suggestions for the selection of appropriate methods based on the research question and data set structure.

  16. AN OVERVIEW OF REDUCED ORDER MODELING TECHNIQUES FOR SAFETY APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Mandelli, D.; Alfonsi, A.; Talbot, P.; Wang, C.; Maljovec, D.; Smith, C.; Rabiti, C.; Cogliati, J.

    2016-10-01

    The RISMC project is developing new advanced simulation-based tools to perform Computational Risk Analysis (CRA) for the existing fleet of U.S. nuclear power plants (NPPs). These tools numerically model not only the thermal-hydraulic behavior of the reactors primary and secondary systems, but also external event temporal evolution and component/system ageing. Thus, this is not only a multi-physics problem being addressed, but also a multi-scale problem (both spatial, µm-mm-m, and temporal, seconds-hours-years). As part of the RISMC CRA approach, a large amount of computationally-expensive simulation runs may be required. An important aspect is that even though computational power is growing, the overall computational cost of a RISMC analysis using brute-force methods may be not viable for certain cases. A solution that is being evaluated to assist the computational issue is the use of reduced order modeling techniques. During the FY2015, we investigated and applied reduced order modeling techniques to decrease the RISMC analysis computational cost by decreasing the number of simulation runs; for this analysis improvement we used surrogate models instead of the actual simulation codes. This article focuses on the use of reduced order modeling techniques that can be applied to RISMC analyses in order to generate, analyze, and visualize data. In particular, we focus on surrogate models that approximate the simulation results but in a much faster time (microseconds instead of hours/days).

  17. A survey of reflectometry techniques with applications to TFTR

    Energy Technology Data Exchange (ETDEWEB)

    Collazo, I.; Stacey, W.M. [Georgia Inst. of Tech., Atlanta, GA (United States); Wilgen, J.; Hanson, G.; Bigelow, T.; Thomas, C.E. [Oak Ridge National Lab., TN (United States); Bretz, N. [Princeton Univ., NJ (United States). Plasma Physics Lab.

    1993-12-01

    This report presents a review of reflectometry with particular attention to eXtraordinary mode (X-mode) reflectometry using the novel technique of dual frequency differential phase. The advantage of using an X-mode wave is that it can probe the edge of the plasma with much higher resolution and using a much smaller frequency range than with the Ordinary mode (O-Mode). The general problem with previous full phase reflectometry techniques is that of keeping track of the phase (on the order of 1000 fringes) as the frequency is swept over the band. The dual frequency phase difference technique has the advantage that since it is keeping track of the phase difference of two frequencies with a constant frequency separation, the fringe counting is on the order of only 3 to 5 fringes. This fringe count, combined with the high resolution of the X-mode wave and the small plasma access requirements of reflectometry, make X-mode reflectometry a very attractive diagnostic for today`s experiments and future fusion devices.

  18. Application of Remote Sensing Techniques for Mapping Shifting Cultivation

    Directory of Open Access Journals (Sweden)

    N.Vijaya Kumari

    2017-01-01

    Full Text Available Shifting cultivation is an ancient and primitive method of cultivation, also referred to as ‘slash and burn’ or ‘rotational bush fallow agricultural system’. The practice mainly involves removal of the forests by primitive slash and burn technique followed by mixed cropping for short period before abandoning the site. Tribals all over India are known to follow the practice of shifting cultivation with some regional variations. The present study has been undertaken to estimate the spatial distribution of podu cultivation in Srikakulam district of Andhra Pradesh by using remote sensing techniques. Results of the present study indicate that an estimated area of 10,491.857 acres of the forest area is under shifting cultivation in Srikakulam district. Shifting cultivation has caused a great deal of environmental degradation. Remote sensing techniques with repetitive coverage and synoptic view provide database for assessing environment degrading practices. Mapping of shifting areas is important not only from ecological point of view but also for management purposes.

  19. Action-specific effects in perception and their potential applications

    OpenAIRE

    Witt, Jessica K.; Linkenauger, Sally; Wickens, Chris

    2016-01-01

    Spatial perception is biased by action. Hills appear steeper and distances appear farther to individuals who would have to exert more effort to transverse the space. Objects appear closer, smaller, and faster when they are easier to obtain. Athletes who are playing better than others see their targets as bigger. These phenomena are collectively known as action-specific effects on perception. In this target article, we review evidence for action-specific effects, including evidence that they r...

  20. Recent advances in knowledge-based paradigms and applications enhanced applications using hybrid artificial intelligence techniques

    CERN Document Server

    Jain, Lakhmi

    2014-01-01

    This book presents carefully selected contributions devoted to the modern perspective of AI research and innovation. This collection covers several areas of applications and motivates new research directions. The theme across all chapters combines several domains of AI research , Computational Intelligence and Machine Intelligence including an introduction to  the recent research and models. Each of the subsequent chapters reveals leading edge research and innovative solution that employ AI techniques with an applied perspective. The problems include classification of spatial images, early smoke detection in outdoor space from video images, emergent segmentation from image analysis, intensity modification in images, multi-agent modeling and analysis of stress. They all are novel pieces of work and demonstrate how AI research contributes to solutions for difficult real world problems that benefit the research community, industry and society.

  1. Performance Testing of Data Delivery Techniques for AJAX Applications

    NARCIS (Netherlands)

    Bozdag, E.; Mesbah, A.; Van Deursen, A.

    2008-01-01

    Preprint of paper published in: Journal of Web Engineering (Rinton Press), 8 (4), 2009 AJAX applications are designed to have high user interactivity and low user-perceived latency. Real-time dynamic web data such as news headlines, stock tickers, and auction updates need to be propagated to the us

  2. Spread Spectrum Techniques and their Applications to Wireless Communications

    DEFF Research Database (Denmark)

    Prasad, Ramjee; Cianca, E.

    2005-01-01

    Spread Spectrum (SS) radio communications is on the verge of potentially explosive commercial development An SS-based multiple access, such as CDMA, has been chosen for 3G wireless communications. Other current applications of SS techniues are in Wireless LANs and Satellite Navigation Systems...

  3. Spread Spectrum Techniques and their Applications to Wireless Communications

    DEFF Research Database (Denmark)

    Prasad, Ramjee; Cianca, E.

    2005-01-01

    Spread Spectrum (SS) radio communications is on the verge of potentially explosive commercial development An SS-based multiple access, such as CDMA, has been chosen for 3G wireless communications. Other current applications of SS techniues are in Wireless LANs and Satellite Navigation Systems. Ho...

  4. Differential Scanning Calorimetry Techniques: Applications in Biology and Nanoscience

    Science.gov (United States)

    Gill, Pooria; Moghadam, Tahereh Tohidi; Ranjbar, Bijan

    2010-01-01

    This paper reviews the best-known differential scanning calorimetries (DSCs), such as conventional DSC, microelectromechanical systems-DSC, infrared-heated DSC, modulated-temperature DSC, gas flow-modulated DSC, parallel-nano DSC, pressure perturbation calorimetry, self-reference DSC, and high-performance DSC. Also, we describe here the most extensive applications of DSC in biology and nanoscience. PMID:21119929

  5. Comprehensive Interpretation Technique for Geophysical Data and Its Applications

    Institute of Scientific and Technical Information of China (English)

    SongJingming; RanXuefeng; HaoHongjiang

    2003-01-01

    Addressed in this paper was the comprehensive interpretation of all kinds of data and its applications in oil/gas exploration. Real examples were used to illustrate the importance of the comprehensive interpretation of gravity/magnetic/electric/seismic data as well as the results.

  6. Differential scanning calorimetry techniques: applications in biology and nanoscience.

    Science.gov (United States)

    Gill, Pooria; Moghadam, Tahereh Tohidi; Ranjbar, Bijan

    2010-12-01

    This paper reviews the best-known differential scanning calorimetries (DSCs), such as conventional DSC, microelectromechanical systems-DSC, infrared-heated DSC, modulated-temperature DSC, gas flow-modulated DSC, parallel-nano DSC, pressure perturbation calorimetry, self-reference DSC, and high-performance DSC. Also, we describe here the most extensive applications of DSC in biology and nanoscience.

  7. Nominal Group Technique and its Applications in Managing Quality in Higher Education

    Directory of Open Access Journals (Sweden)

    Rafikul Islam

    2011-09-01

    Full Text Available Quality management is an important aspect in all kinds of businesses – manufacturing or service. Idea generation plays a pivotal role in managing quality in organizations. It is thenew and innovative ideas which can help corporations to survive in the turbulent business environment. Research in group dynamics has shown that more ideas are generated by individuals working alone but in a group environment than the individuals engaged in a formal group discussion. In Nominal Group Technique (NGT, individuals work alone but in a group setting. This paper shows how NGT can be applied to generate large number of ideas to solve quality related problems specifically in Malaysian higher education setting. The paper also discusses the details of NGT working procedure andexplores the areas of its further applications.

  8. Design and integration of components for site specific control of fertilizer application

    NARCIS (Netherlands)

    Bergeijk, van J.

    2001-01-01

    Keywords: Precision Agriculture, Site Specific Agriculture, Global Positioning System, GPS, Fertilizer Application, Information System.

    Spatial and temporal variability in soil, crop and climate characteristics results in non optimal use of fertilizers when the application

  9. Molecular Probes in Marine Ecology: Concepts, Techniques and Applications

    Science.gov (United States)

    1990-03-12

    dynamics of benthic marine invertebrates, focusing specifically on scleractinian corals and gorgonian soft corals . I have initiated a study of genetic...Ecological Aspects Tom Chen, Center of Marino Biotechnology, University of Maryland, Baltimore, ND July 1 10330 A Translational Regulatory Mechanism for...alaae, coral . covepods. microflaaellates. dinoflacellates) (Rob Rovan). Isolate organisms and prepare DNA. Amplify rDNA usina universal (or zooxanthella

  10. Applications of the site-specific recombinase Cre to the study of genomic imprinting.

    Science.gov (United States)

    Oh-McGinnis, Rosemary; Jones, Meaghan J; Lefebvre, Louis

    2010-07-01

    The development of gene targeting approaches has had a tremendous impact on the functional analysis of the mouse genome. A specific application of this technique has been the adaptation of the bacteriophage P1 Cre/loxP site-specific recombinase system which allows for the precise recombination between two loxP sites, resulting in deletion or inversion of the intervening sequences. Because of the efficiency of this system, it can be applied to conditional deletions of relatively short coding sequences or regulatory elements but also to more extensive chromosomal rearrangement strategies. Both mechanistic and functional studies of genomic imprinting have benefited from the development of the Cre/loxP technology. Since imprinted genes within large chromosomal regions are regulated by the action of cis-acting sequences known as imprinting centers, chromosomal engineering approaches are particularly well suited to the elucidation of long-range mechanisms controlling the imprinting of autosomal genes. Here we review the applications of the Cre/loxP technology to the study of genomic imprinting, highlight important insights gained from these studies and discuss future directions in the field.

  11. Application of Active Flow Control Technique for Gust Load Alleviation

    Institute of Scientific and Technical Information of China (English)

    XU Xiaoping; ZHU Xiaoping; ZHOU Zhou; FAN Ruijun

    2011-01-01

    A new gust load alleviation technique is presented in this paper based on active flow control.Numerical studies are conducted to investigate the beneficial effects on the aerodynamic characteristics of the quasi “Global Hawk” airfoil using arrays of jets during the gust process.Based on unsteady Navier-Stokes equations,the grid-velocity method is introduced to simulate the gust influence,and dynamic response in vertical gust flow perturbation is investigated for the airfoil as well.An unsteady surface transpiration boundary condition is enforced over a user specified portion of the airfoil's surface to emulate the time dependent velocity boundary conditions.Firstly,after applying this method to simulate typical NACA0006 airfoil gust response to a step change in the angle of attack,it shows that the indicial responses of the airfoil make good agreement with the exact theoretical values and the calculated values in references.Furthermore,gust response characteristic for the quasi “Global Hawk” airfoil is analyzed.Five kinds of flow control techniques are introduced as steady blowing,steady suction,unsteady blowing,unsteady suction and synthetic jets.The physical analysis of the influence on the effects of gust load alleviation is proposed to provide some guidelines for practice.Numerical results have indicated that active flow control technique,as a new technology of gust load alleviation,can affect and suppress the fluid disturbances caused by gust so as to achieve the purpose of gust load alleviation.

  12. Application of Kalman Filtering Techniques for Microseismic Event Detection

    Science.gov (United States)

    Baziw, E.; Weir-Jones, I.

    - Microseismic monitoring systems are generally installed in areas of induced seismicity caused by human activity. Induced seismicity results from changes in the state of stress which may occur as a result of excavation within the rock mass in mining (i.e., rockbursts), and changes in hydrostatic pressures and rock temperatures (e.g., during fluid injection or extraction) in oil exploitation, dam construction or fluid disposal. Microseismic monitoring systems determine event locations and important source parameters such as attenuation, seismic moment, source radius, static stress drop, peak particle velocity and seismic energy. An essential part of the operation of a microseismic monitoring system is the reliable detection of microseismic events. In the absence of reliable, automated picking techniques, operators rely upon manual picking. This is time-consuming, costly and, in the presence of background noise, very prone to error. The techniques described in this paper not only permit the reliable identification of events in cluttered signal environments they have also enabled the authors to develop reliable automated event picking procedures. This opens the way to use microseismic monitoring as a cost-effective production/operations procedure. It has been the experience of the authors that in certain noisy environments, the seismic monitoring system may trigger on and subsequently acquire substantial quantities of erroneous data, due to the high energy content of the ambient noise. Digital filtering techniques need to be applied on the microseismic data so that the ambient noise is removed and event detection simplified. The monitoring of seismic acoustic emissions is a continuous, real-time process and it is desirable to implement digital filters which can also be designed in the time domain and in real-time such as the Kalman Filter. This paper presents a real-time Kalman Filter which removes the statistically describable background noise from the recorded

  13. Application of Neuro-Fuzzy Techniques for Solar Radiation

    OpenAIRE

    W. A. Rahoma; U. A. Rahoma; A. H. Hassan

    2011-01-01

    Problem statement: The prediction is very useful in solar energy applications because it permits to estimate solar data for locations where measurements are not available. The developed artificial intelligence models predict the solar radiation time series more effectively compared to the conventional procedures based on the clearness index. Approach: The forecasting ability of some models could be further enhanced with the use of additional meteorological parameters. After having simulated m...

  14. A Survey on Hough Transform, Theory, Techniques and Applications

    OpenAIRE

    Hassanein, Allam Shehata; Mohammad, Sherien; Sameer, Mohamed; Ragab, Mohammad Ehab

    2015-01-01

    For more than half a century, the Hough transform is ever-expanding for new frontiers. Thousands of research papers and numerous applications have evolved over the decades. Carrying out an all-inclusive survey is hardly possible and enormously space-demanding. What we care about here is emphasizing some of the most crucial milestones of the transform. We describe its variations elaborating on the basic ones such as the line and circle Hough transforms. The high demand for storage and computat...

  15. Optical and digital microscopic imaging techniques and applications in pathology

    OpenAIRE

    Xiaodong Chen; Bin Zheng; Hong Liu

    2011-01-01

    The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy to facilitate clinical screening and diagnosis. This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications o...

  16. APPLICATION OF NONLINEAR WATERMARK TECHNIQUES IN DIGITAL LIBRARIES

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    A digital watermark is an invisible mark embedded in a digital image that may be used for a number of different purposes including copyright protection. Due to the urgent need for protecting the copyright of digital products in digital library, digital watermarking has been proposed as a solution to this problem. This letter describes potential situations that nonlinear theory can be used to enhance robustness and security of the watermark in digital library. Some nonlinear watermark techniques have been enumerated. Experimental results show that the proposed scheme is superior to the general watermark scheme both in security and robustness in digital library.

  17. Polarization changing technique in macrocosm and it's application to radar

    Institute of Scientific and Technical Information of China (English)

    潘健; 毛二可

    2004-01-01

    A new model of air-surveillance radar (named polarization changing in macrocosm radar: PCM radar), which makes use of the polarization changing technique in macrocosm, is presented in this paper. On basis of careful selection of representative 98 states of polarization in macrocosm, PCM radar can not only perform transmitting and receiving polarization matching for various targets, consequently make full use of transmitting and receiving signals of radar, but also improve the capability against active interference and jamming. Experimental test in air defense early-warning radar system demonstrates that it can effectively enhance radar performance.

  18. Application of Adaptive Threading Technique to Hot Strip Mill

    Institute of Scientific and Technical Information of China (English)

    DING Jing-guo; HU Xian-lei; JIAO Jing-min; SHE Guang-fu; LIU Xiang-hua

    2008-01-01

    Thickness deviation of hot strip rolling needs to be strictly controlled in the computer system.An adaptive threading technique was researched,in which the measured data from threaded stands were used to predict thickness and material hardness errors,to modify the setup for the remaining unthreaded stands.After the adaptive threading model was used online on the hot strip mill of the Panzhihua Iron and Steel Group Co Ltd,the thickness deviation was decreased obviously.The hit rate of thickness control of different steel grades increases.

  19. Application of the Molecular Combing Technique to Starch Granules

    Directory of Open Access Journals (Sweden)

    Zhong-Dong Liu

    2009-10-01

    Full Text Available The molecular combing technique was used to dissociate the nanostructural units of starch granules from the starch fragments after a gelatinization process. With the help of atomic force microscopy (AFM, we observed that some nanostructural chains were just flowing out of the granules. It proves that there are substantive nanostructural units in the starch granules, a phenomenon not previously observed, so these nanostructural units were defined as suspected intermediates. Furthermore, we conclude that blocklets of starch granules are formed through twisting or distortion of nanochains.

  20. Remark on the applicability of Campbelling techniques for transient signals

    Energy Technology Data Exchange (ETDEWEB)

    Elter, Zs., E-mail: zsolt@nephy.chalmers.se [Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Göteborg (Sweden); CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance (France); Pázsit, I. [Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Göteborg (Sweden); Jammes, C. [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance (France)

    2016-03-21

    The signals of fission chambers are traditionally evaluated with Campbelling methods at medium count rates. Lately there has been a growing interest in the extension of Campbelling methods to cover a wider range of count rates. These methods are applied to measure the neutron flux in the stationary state of the reactor. However, there has not been any attempt to generalize these techniques for transient reactor states. This short note is devoted to a discussion of this question. It is shown through analytic and numerical calculations that for practical reasons the traditional, stationary Campbelling methods can be applied for transient scenarios as well.

  1. New optical tomographic & topographic techniques for biomedical applications

    Science.gov (United States)

    Buytaert, Jan

    The mammalian middle ear contains the eardrum and the three auditory ossicles, and forms an impedance match between sound in air and pressure waves in the fluid of the inner ear. Without this intermediate system, with its unsurpassed efficiency and dynamic range, we would be practically deaf. Physics-based modeling of this extremely complex mechanical system is necessary to help our basic understanding of the functioning of hearing. Highly realistic models will make it possible to predict the outcome of surgical interventions and to optimize design of ossicle prostheses and active middle ear implants. To obtain such models and with realistic output, basic input data is still missing. In this dissertation I developed and used two new optical techniques to obtain two essential sets of data: accurate three-dimensional morphology of the middle ear structures, and elasticity parameters of the eardrum. The first technique is a new method for optical tomography of macroscopic biomedical objects, which makes it possible to measure the three-dimensional geometry of the middle ear ossicles and soft tissues which are connecting and suspending them. I made a new and high-resolution version of this orthogonal-plane fluorescence optical sectioning method, to obtain micrometer resolution in macroscopic specimens. The result is thus a complete 3-D model of the middle (and inner) ear of gerbil in unprecedented quality. On top of high-resolution morphological models of the middle ear structures, I applied the technique in other fields of research as well. The second device works according to a new optical profilometry technique which allows to measure shape and deformations of the eardrum and other membranes or objects. The approach is called projection moire profilometry, and creates moire interference fringes which contain the height information. I developed a setup which uses liquid crystal panels for grid projection and optical demodulation. Hence no moving parts are present and

  2. Image blending techniques and their application in underwater mosaicing

    CERN Document Server

    Prados, Ricard; Neumann, László

    2014-01-01

    This work proposes strategies and solutions to tackle the problem of building photo-mosaics of very large underwater optical surveys, presenting contributions to the image preprocessing, enhancing and blending steps, and resulting in an improved visual quality of the final photo-mosaic. The text opens with a comprehensive review of mosaicing and blending techniques, before proposing an approach for large scale underwater image mosaicing and blending. In the image preprocessing step, a depth dependent illumination compensation function is used to solve the non-uniform illumination appearance du

  3. High-specific-energy secondary batteries and their applications

    Science.gov (United States)

    Cairns, E. J.

    1983-01-01

    The state of development, problems, and possible applications are discussed for a number of rechargeable cells, which include: lead/lead dioxide, cadmium/nickel oxide, hydrogen/nickel oxide, iron/nickel oxide, zinc/nickel oxide, zinc/silver oxide, zinc/halogen, lithium/titanium disulfide, lithium/iron sulfide, and sodium/sulfur cells.

  4. Application of Creativity Techniques in the Creation of Organizational Strategies

    Directory of Open Access Journals (Sweden)

    Alireza Aslani

    2012-08-01

    Full Text Available The majority of studies in the field of organizational strategies have concentrated on strategy formulation, distinct from strategy implementation. Disunion of these two processes often leads to disappointing results in the implementation of strategy. In such a condition, the creation of a suitable strategy in a way that could resolve the divergence of formulation from implementation is suggested by researchers. This means that the implementers of a strategy turn into the formulators. Therefore, presenting creative ideas and solutions is encouraged between related organizational staff at different levels. Noting that the possibility of emerging creative ideas in organizational meetings between persons from different organizational levels is low, fostering creativity and innovation techniques can be an ideal solution for successful group meetings. In this paper, after introducing the effective criteria that should be considered in the creation of collective action strategies in organizations, the suitable techniques for fostering creativity in this kind of meeting will be ranked based on the Fuzzy MADM approach.

  5. Application of magnetic resonance techniques for imaging tumour physiology

    Energy Technology Data Exchange (ETDEWEB)

    Stubbs, M. [Saint George' s Hospital Medical School, London (United Kingdom). Dept. of Biochemistry

    1999-07-01

    Magnetic resonance (MR) techniques have the unique ability to measure in vivo the biochemical content of living tissue in the body in a dynamic, non-invasive and non-destructive manner. MR also permits serial investigations of steady-state tumour physiology and biochemistry, as well as the response of a tumour to treatment. Magnetic resonance imaging (MRI), Magnetic resonance spectroscopy (MRS) and a mixture of the two techniques (spectroscopic imaging) allow some physiological parameters, for example pH, to be 'imaged'. Using these methods, information on tissue bioenergetics and phospolipid membrane turnover, pH, hypoxia, oxygenation, and various aspects of vascularity including blood flow, angiogenesis, permeability and vascular volume can be obtained. In addition, MRS methods can be used for monitoring anticancer drugs (e.g. 5FU, ifosfamide) and their metabolites at their sites of action. The role of these state-of-the-art MR methods in imaging tumour physiology and their potential role in the clinic are discussed. (orig.)

  6. The application of near infrared spectroscopy (NIR technique for

    Directory of Open Access Journals (Sweden)

    Sandor Barabassy

    2001-06-01

    Full Text Available The production of cow’s milk in Hungary fluctuates by 15-20 % annualy. Surplus milk is dried into powder and can also be converted to modified milk powders using techniques such as ultra filtration. From approximetely 20.000 tonnes, of all milk powder types, 3.000 tonnes, is converted using ultra filtration technology. Multivariable near infrared (NIR calibration was performed on powder mixtures of whole milk, skimmed milk, whey, retenate (protein concentrate and lactose for rapid fat, protein, lactose, water and ash content determination. More than 150 samples were prepared and measured in two NIRS labs (Scottish Agriculture College – SAC – Aberdeen and University of Horticulture and Food Science - UHFS – Budapest. The results obtained from the same samples were compared. The aims of the study were: 1. Rapid quantitative and qualitative determination of mixtures of milk powder products using NIR technique. 2. Comparison of the results achieved in Aberdeen (SAC and Budapest (UHFS institutes. The mass per cent varied between 0.0-2.8% for fat, 0.0-80% for protein, 6.6-100 % for lactose, 0.0-5.0 % for water and 0.0-8.0 % for ash. High correlation coefficients (0.97-0.99 were found for all five components.

  7. Application of transport phenomena analysis technique to cerebrospinal fluid.

    Science.gov (United States)

    Lam, C H; Hansen, E A; Hall, W A; Hubel, A

    2013-12-01

    The study of hydrocephalus and the modeling of cerebrospinal fluid flow have proceeded in the past using mathematical analysis that was very capable of prediction phenomenonologically but not well in physiologic parameters. In this paper, the basis of fluid dynamics at the physiologic state is explained using first established equations of transport phenomenon. Then, microscopic and molecular level techniques of modeling are described using porous media theory and chemical kinetic theory and then applied to cerebrospinal fluid (CSF) dynamics. Using techniques of transport analysis allows the field of cerebrospinal fluid dynamics to approach the level of sophistication of urine and blood transport. Concepts such as intracellular and intercellular pathways, compartmentalization, and tortuosity are associated with quantifiable parameters that are relevant to the anatomy and physiology of cerebrospinal fluid transport. The engineering field of transport phenomenon is rich and steeped in architectural, aeronautical, nautical, and more recently biological history. This paper summarizes and reviews the approaches that have been taken in the field of engineering and applies it to CSF flow.

  8. Category Specificity in Normal Episodic Learning: Applications to Object Recognition and Category-Specific Agnosia

    Science.gov (United States)

    Bukach, Cindy M.; Bub, Daniel N.; Masson, Michael E. J.; Lindsay, D. Stephen

    2004-01-01

    Studies of patients with category-specific agnosia (CSA) have given rise to multiple theories of object recognition, most of which assume the existence of a stable, abstract semantic memory system. We applied an episodic view of memory to questions raised by CSA in a series of studies examining normal observers' recall of newly learned attributes…

  9. Reusing UML specifications in a constrained application domain

    NARCIS (Netherlands)

    Blok, M.C.; Cybulski, J.L.

    1998-01-01

    This article describes a method of reusing computer software designed in UML (Unified Modelling Language) with the aid of a domain model. The method's main strength is the possibility of software reuse at the earliest stages of the development life cycle, i.e. specification of use cases and their ev

  10. 46 CFR 161.006-1 - Applicable specifications.

    Science.gov (United States)

    2010-10-01

    ...: SPECIFICATIONS AND APPROVAL ELECTRICAL EQUIPMENT Searchlights, Motor Lifeboat, for Merchant Vessels § 161.006-1...: 42S5—Screws, machine, cap and set, and nuts. 43B11—Bolts, nuts, studs, and tap-rivets (and materials... Society for Testing and Materials, 100 Barr Harbor Drive, West Conshohocken, PA 19428-2959....

  11. 42 CFR 447.53 - Applicability; specification; multiple charges.

    Science.gov (United States)

    2010-10-01

    ... HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PAYMENTS FOR SERVICES Payments: General...; specification; multiple charges. (a) Basic requirements. Except as specified in paragraph (b) of this section... his income required for personal needs, for medical care costs are excluded from cost sharing. (4...

  12. Advanced Multipath Mitigation Techniques for Satellite-Based Positioning Applications

    Directory of Open Access Journals (Sweden)

    Mohammad Zahidul H. Bhuiyan

    2010-01-01

    Full Text Available Multipath remains a dominant source of ranging errors in Global Navigation Satellite Systems (GNSS, such as the Global Positioning System (GPS or the future European satellite navigation system Galileo. Multipath is generally considered undesirable in the context of GNSS, since the reception of multipath can make significant distortion to the shape of the correlation function used for time delay estimation. However, some wireless communications techniques exploit multipath in order to provide signal diversity though in GNSS, the major challenge is to effectively mitigate the multipath, since we are interested only in the satellite-receiver transit time offset of the Line-Of-Sight (LOS signal for the receiver's position estimate. Therefore, the multipath problem has been approached from several directions in order to mitigate the impact of multipath on navigation receivers, including the development of novel signal processing techniques. In this paper, we propose a maximum likelihood-based technique, namely, the Reduced Search Space Maximum Likelihood (RSSML delay estimator, which is capable of mitigating the multipath effects reasonably well at the expense of increased complexity. The proposed RSSML attempts to compensate the multipath error contribution by performing a nonlinear curve fit on the input correlation function, which finds a perfect match from a set of ideal reference correlation functions with certain amplitude(s, phase(s, and delay(s of the multipath signal. It also incorporates a threshold-based peak detection method, which eventually reduces the code-delay search space significantly. However, the downfall of RSSML is the memory requirement which it uses to store the reference correlation functions. The multipath performance of other delay-tracking methods previously studied for Binary Phase Shift Keying-(BPSK- and Sine Binary Offset Carrier- (SinBOC- modulated signals is also analyzed in closed loop model with the new Composite

  13. Searching for Alternative Plasmonic Materials for Specific Applications

    Directory of Open Access Journals (Sweden)

    Amit Bansal

    2014-01-01

    Full Text Available The localized surface plasmon resonance (LSPR based optical properties such as light scattering, absorption, and extinction efficiencies of multimetallic and metal-semiconductor nanostructures will be studied. The effect of size, surrounding medium, interaction between the particles, composition of the particles, and substrate on LSPR peak position, its line width, and maxima of cross-sections will also be discussed to optimize the selected systems for various applications like plasmonic sensors and biomedical applications and to enhance the efficiency of solar cells. Therefore, by varying all these factors, the LSPR peak of multimetallic and metal-semiconductor nanostructures can be tuned over the entire UV-visible to infrared (IR region of the electromagnetic spectrum. Moreover the optical properties of underlying semiconductor materials can be enhanced by combining the semiconductor with noble metal nanoparticles.

  14. Transcranial Doppler: Techniques and advanced applications: Part 2

    Directory of Open Access Journals (Sweden)

    Arvind K Sharma

    2016-01-01

    Full Text Available Transcranial Doppler (TCD is the only diagnostic tool that can provide continuous information about cerebral hemodynamics in real time and over extended periods. In the previous paper (Part 1, we have already presented the basic ultrasound physics pertaining to TCD, insonation methods, and various flow patterns. This article describes various advanced applications of TCD such as detection of right-to-left shunt, emboli monitoring, vasomotor reactivity (VMR, monitoring of vasospasm in subarachnoid hemorrhage (SAH, monitoring of intracranial pressure, its role in stoke prevention in sickle cell disease, and as a supplementary test for confirmation of brain death.

  15. Application of advanced coating techniques to rocket engine components

    Science.gov (United States)

    Verma, S. K.

    1988-01-01

    The materials problem in the space shuttle main engine (SSME) is reviewed. Potential coatings and the method of their application for improved life of SSME components are discussed. A number of advanced coatings for turbine blade components and disks are being developed and tested in a multispecimen thermal fatigue fluidized bed facility at IIT Research Institute. This facility is capable of producing severe strains of the degree present in blades and disk components of the SSME. The potential coating systems and current efforts at IITRI being taken for life extension of the SSME components are summarized.

  16. Electronically steerable millimeter wave antenna techniques for space shuttle applications

    Science.gov (United States)

    Kummer, W. H.

    1975-01-01

    A large multi-function antenna aperture and related components are described which will perform electronic steering of one or more beams for two of the three applications envisioned: (1) communications, (2) radar, and (3) radiometry. The array consists of a 6-meter folded antenna that fits into two pallets. The communications frequencies are 20 and 30 GHz, while the radar is to operate at 13.9 GHz. Weight, prime power, and volumes are given parametrically; antenna designs, electronics configurations, and mechanical design were studied.

  17. Clinical application of modern ultrasound techniques after liver transplantation.

    Science.gov (United States)

    Teegen, Eva Maria; Denecke, Timm; Eisele, Robert; Lojewski, Christian; Neuhaus, Peter; Chopra, Sascha Santosh

    2016-10-01

    Liver transplantation has been established as a first-line therapy for a number of indications. Conventional ultrasound and contrast-enhanced ultrasound (CEUS) are methods of choice during the postoperative period as a safe and fast tool to detect potential complications and to enable early intervention if necessary. CEUS increases diagnostic quality and is an appropriate procedure for the examination of vessels and possibly bile ducts. This article presents the state of the art of ultrasound application during the early period after liver transplantation. It addresses common vascular complications and describes the identification of postoperative abnormal findings using ultrasound and CEUS.

  18. Transient analysis of power systems solution techniques, tools and applications

    CERN Document Server

    Martinez-Velasco, J

    2014-01-01

    A comprehensive introduction and up-to-date reference to SiC power semiconductor devices covering topics from material properties to applicationsBased on a number of breakthroughs in SiC material science and fabrication technology in the 1980s and 1990s, the first SiC Schottky barrier diodes (SBDs) were released as commercial products in 2001.  The SiC SBD market has grown significantly since that time, and SBDs are now used in a variety of power systems, particularly switch-mode power supplies and motor controls.  SiC power MOSFETs entered commercial production in 2011, providing rugged, hig

  19. Modern EMC analysis techniques II models and applications

    CERN Document Server

    Kantartzis, Nikolaos V

    2008-01-01

    The objective of this two-volume book is the systematic and comprehensive description of the most competitive time-domain computational methods for the efficient modeling and accurate solution of modern real-world EMC problems. Intended to be self-contained, it performs a detailed presentation of all well-known algorithms, elucidating on their merits or weaknesses, and accompanies the theoretical content with a variety of applications. Outlining the present volume, numerical investigations delve into printed circuit boards, monolithic microwave integrated circuits, radio frequency microelectro

  20. [The manipulation technique and clinical application of kinetic cupping].

    Science.gov (United States)

    Luo, Rong; Liu, Qi; Sun, Dan

    2013-07-01

    The characteristic of kinetic cupping is explained from treatment principles, manipulation and clinical application. The kinetic cupping is a new particular therapy that combines traditional cupping and kinetic therapy. With cups on the patient, limb action like flexion-extension, adduction-abduction and rotation is made to reinforce clinical effects, which has simple and safe manipulation, obvious efficacy and is well accepted by patient. It has more obvious advantage for pain that was caused by large-area soft tissue injury and discomfort where acupuncture is not appropriate.

  1. Modern applications of NMR tomography in physical chemistry. The characteristic features of the technique and its applications to studies of liquid-containing objects

    Energy Technology Data Exchange (ETDEWEB)

    Koptyug, Igor V; Sagdeev, Renad Z [International Tomography Center, Siberian Branch of the Russian Academy of Sciences, Novosibirsk (Russian Federation)

    2002-07-31

    This review concerns the state-of-the-art in the field of NMR tomography. The scope and limitations of the method, its capabilities, and some of the most widely used applications in physical chemistry are discussed. It is demonstrated that the technique is able to provide a vast variety of information about the state of objects under study and on the physicochemical processes occurring in them, which can be gained owing to the specific features of the technique. The review predominantly covers the studies of the structure and properties of various liquid-containing objects. The bibliography includes 232 references.

  2. New approaches in intelligent image analysis techniques, methodologies and applications

    CERN Document Server

    Nakamatsu, Kazumi

    2016-01-01

    This book presents an Introduction and 11 independent chapters, which are devoted to various new approaches of intelligent image processing and analysis. The book also presents new methods, algorithms and applied systems for intelligent image processing, on the following basic topics: Methods for Hierarchical Image Decomposition; Intelligent Digital Signal Processing and Feature Extraction; Data Clustering and Visualization via Echo State Networks; Clustering of Natural Images in Automatic Image Annotation Systems; Control System for Remote Sensing Image Processing; Tissue Segmentation of MR Brain Images Sequence; Kidney Cysts Segmentation in CT Images; Audio Visual Attention Models in Mobile Robots Navigation; Local Adaptive Image Processing; Learning Techniques for Intelligent Access Control; Resolution Improvement in Acoustic Maps. Each chapter is self-contained with its own references. Some of the chapters are devoted to the theoretical aspects while the others are presenting the practical aspects and the...

  3. The Needling Technique and Clinical Application of Point Zhibian

    Institute of Scientific and Technical Information of China (English)

    张远东

    2004-01-01

    @@ The Needling Technique The patient is asked to lie in a lateral or prone position. A No. 28 filiform needle of 3 cun is inserted perpendicularly into the point Zhibian (BL 54), with the direction of the needle tip varying according to the different conditions of the diseases. The needle can be directed in three directions, the first along the sciatic nerve; the second pointing to the genitals; and the third pointing to the anus. The reinforcing,reducing, or even needling manipulation can be used,and the needling depth can be deep or superficial.The needling can also be applied in combination with the warm-needle, cupping, and point-injection.

  4. Development and application of animation technique by using PIV database

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Y.H. [Korea Maritime University, Pusan (Korea); Choi, J.W. [IIT, Pusan (Korea); Seo, M.S.; Ahn, K.H.; Kim, M.Y. [Graduate School, Korea Maritime University, Pusan (Korea)

    1998-11-01

    Animation technique from the PIV database is particularly emphasized to give macroscopic and quantitative description of complex flow fields. As an example, a Karman vortex street(Re=2x10{sup 4}) from the two-dimensional cylinder immersed in a circular water tank is visualized and processed by PIV. Cross correlation algorithm to estimate the peak coefficients is adopted for the identification and its performance is compared to that of the FFT routine. All animation jobs are implemented completely on single personal computer. Compressed digital images are obtained by Motion-JPEG board and various AVI files are finally obtained through graphic processes. As results, continuous pictures of the spatial distribution of the instant vectors, turbulent intensity, turbulent kinetic energy, kinetic energy, vorticity and three Reynolds stress components are animated dynamically on PC monitor. And streak lines, trajectories and streamlines are also displayed in real-time sense. (author). 10 refs., 18 figs.

  5. Postselection technique for quantum channels with applications to quantum cryptography.

    Science.gov (United States)

    Christandl, Matthias; König, Robert; Renner, Renato

    2009-01-16

    We propose a general method for studying properties of quantum channels acting on an n-partite system, whose action is invariant under permutations of the subsystems. Our main result is that, in order to prove that a certain property holds for an arbitrary input, it is sufficient to consider the case where the input is a particular de Finetti-type state, i.e., a state which consists of n identical and independent copies of an (unknown) state on a single subsystem. Our technique can be applied to the analysis of information-theoretic problems. For example, in quantum cryptography, we get a simple proof for the fact that security of a discrete-variable quantum key distribution protocol against collective attacks implies security of the protocol against the most general attacks. The resulting security bounds are tighter than previously known bounds obtained with help of the exponential de Finetti theorem.

  6. Risk assessment techniques with applicability in marine engineering

    Science.gov (United States)

    Rudenko, E.; Panaitescu, F. V.; Panaitescu, M.

    2015-11-01

    Nowadays risk management is a carefully planned process. The task of risk management is organically woven into the general problem of increasing the efficiency of business. Passive attitude to risk and awareness of its existence are replaced by active management techniques. Risk assessment is one of the most important stages of risk management, since for risk management it is necessary first to analyze and evaluate risk. There are many definitions of this notion but in general case risk assessment refers to the systematic process of identifying the factors and types of risk and their quantitative assessment, i.e. risk analysis methodology combines mutually complementary quantitative and qualitative approaches. Purpose of the work: In this paper we will consider as risk assessment technique Fault Tree analysis (FTA). The objectives are: understand purpose of FTA, understand and apply rules of Boolean algebra, analyse a simple system using FTA, FTA advantages and disadvantages. Research and methodology: The main purpose is to help identify potential causes of system failures before the failures actually occur. We can evaluate the probability of the Top event.The steps of this analize are: the system's examination from Top to Down, the use of symbols to represent events, the use of mathematical tools for critical areas, the use of Fault tree logic diagrams to identify the cause of the Top event. Results: In the finally of study it will be obtained: critical areas, Fault tree logical diagrams and the probability of the Top event. These results can be used for the risk assessment analyses.

  7. Estrone specific molecularly imprinted polymeric nanospheres: synthesis, characterization and applications for electrochemical sensor development.

    Science.gov (United States)

    Congur, Gulsah; Senay, Hilal; Turkcan, Ceren; Canavar, Ece; Erdem, Arzum; Akgol, Sinan

    2013-06-28

    The aim of this study is (i) to prepare estrone-imprinted nanospheres (nano-EST-MIPs) and (ii) to integrate them into the electrochemical sensor as a recognition layer. N-methacryloyl-(l)-phenylalanine (MAPA) was chosen as the complexing monomer. Firstly, estrone (EST) was complexed with MAPA and the EST-imprinted poly(2-hyroxyethylmethacrylate-co-N-methacryloyl-(l)-phenylalanine) [EST-imprinted poly(HEMA-MAPA)] nanospheres were synthesized by surfactant- free emulsion polymerization method. The specific surface area of the EST-imprinted poly(HEMA-MAPA) nanospheres was found to be 1275 m2/g with a size of 163.2 nm in diameter. According to the elemental analysis results, the nanospheres contained 95.3 mmole MAPA/g nanosphere. The application of EST specific MIP nanospheres for the development of an electrochemical biosensor was introduced for the first time in our study by using electrochemical impedance spectroscopy (EIS) technique. This nano-MIP based sensor presented a great specificity and selectivity for EST.

  8. Epsilon Haemoglobin Specific Antibodies with Applications in Noninvasive Prenatal Diagnosis

    Science.gov (United States)

    Sørensen, Morten Dræby; Gonzalez Dosal, Regina; Jensen, Kim Bak; Christensen, Britta; Kølvraa, Steen; Jensen, Uffe Birk; Kristensen, Peter

    2009-01-01

    Invasive procedures for prenatal diagnosis are associated with increased risk of abortion; thus, development of noninvasive procedures would be beneficial. Based on the observation that embryonic nucleated red blood cell (NRBC) crosses the placenta and enters the circulation of pregnant women, the ability to identify such cell would allow development of such procedures. Identification of NRBCs in blood samples would be possible provided that specific antibodies are available. Here we have isolated recombinant antibodies using phage display. From the panel of antibody fragments specifically recognising ε-Hb, one was chosen for further characterization, DAb1. DAb1 binds to ε-Hb both in Western blots and immunocytochemistry. Several ε-Hb positive cells were detected in a blood sample taken as postchorionic villus sampling (CVS). To evaluate the sensitivity of the method, K562 cells (which express ε-Hb) were spiked in a blood sample followed by staining in solution and FACS analysis. PMID:19636421

  9. Epsilon Haemoglobin Specific Antibodies with Applications in Noninvasive Prenatal Diagnosis

    Directory of Open Access Journals (Sweden)

    Morten Dræby Sørensen

    2009-01-01

    Full Text Available Invasive procedures for prenatal diagnosis are associated with increased risk of abortion; thus, development of noninvasive procedures would be beneficial. Based on the observation that embryonic nucleated red blood cell (NRBC crosses the placenta and enters the circulation of pregnant women, the ability to identify such cell would allow development of such procedures. Identification of NRBCs in blood samples would be possible provided that specific antibodies are available. Here we have isolated recombinant antibodies using phage display. From the panel of antibody fragments specifically recognising ε-Hb, one was chosen for further characterization, DAb1. DAb1 binds to ε-Hb both in Western blots and immunocytochemistry. Several ε-Hb positive cells were detected in a blood sample taken as postchorionic villus sampling (CVS. To evaluate the sensitivity of the method, K562 cells (which express ε-Hb were spiked in a blood sample followed by staining in solution and FACS analysis.

  10. Time analysis for screw application: traditional lag technique versus self-tapping lag technique.

    Science.gov (United States)

    Gonzalez, J V; Trout, B M; Stuck, R M; Vrbos, L A

    1997-01-01

    A study was conducted to compare the procedural time of a 2.7-mm. fully threaded cortical screw versus a self-tapping, 2.4-mm. lag screw, which is reported to eliminate the need for overdrilling and tapping. The screws were applied by four board-certified podiatric and orthopedic physicians and four second-year podiatric and orthopedic residents. Each screw was placed through two 8-mm. layers of Last-a-foam, and the participants were timed for length of application of four screws from each system per week. The trials were repeated weekly for 4 weeks. The results showed a statistically significant difference between the length of time for insertion between a traditional cortical screw and a self-tapping lag screw, regardless of physician experience.

  11. VLSI synthesis of digital application specific neural networks

    Science.gov (United States)

    Beagles, Grant; Winters, Kel

    1991-01-01

    Neural networks tend to fall into two general categories: (1) software simulations, or (2) custom hardware that must be trained. The scope of this project is the merger of these two classifications into a system whereby a software model of a network is trained to perform a specific task and the results used to synthesize a standard cell realization of the network using automated tools.

  12. Theory of stochastic differential equations with jumps and applications mathematical and analytical techniques with applications to engineering

    CERN Document Server

    SITU, Rong

    2005-01-01

    Derivation of Ito's formulas, Girsanov's theorems and martingale representation theorem for stochastic DEs with jumpsApplications to population controlReflecting stochastic DE techniqueApplications to the stock market. (Backward stochastic DE approach)Derivation of Black-Scholes formula for market with and without jumpsNon-linear filtering problems with jumps.

  13. Recent advances in bioprinting techniques: approaches, applications and future prospects.

    Science.gov (United States)

    Li, Jipeng; Chen, Mingjiao; Fan, Xianqun; Zhou, Huifang

    2016-09-20

    Bioprinting technology shows potential in tissue engineering for the fabrication of scaffolds, cells, tissues and organs reproducibly and with high accuracy. Bioprinting technologies are mainly divided into three categories, inkjet-based bioprinting, pressure-assisted bioprinting and laser-assisted bioprinting, based on their underlying printing principles. These various printing technologies have their advantages and limitations. Bioprinting utilizes biomaterials, cells or cell factors as a "bioink" to fabricate prospective tissue structures. Biomaterial parameters such as biocompatibility, cell viability and the cellular microenvironment strongly influence the printed product. Various printing technologies have been investigated, and great progress has been made in printing various types of tissue, including vasculature, heart, bone, cartilage, skin and liver. This review introduces basic principles and key aspects of some frequently used printing technologies. We focus on recent advances in three-dimensional printing applications, current challenges and future directions.

  14. Inter-cooperative collective intelligence techniques and applications

    CERN Document Server

    Bessis, Nik

    2014-01-01

    This book covers the latest advances in the rapid growing field of inter-cooperative collective intelligence aiming the integration and cooperation of various computational resources, networks and intelligent processing paradigms to collectively build intelligence and advanced decision support and interfaces for end-users. The book brings a comprehensive view of the state-of-the-art in the field of integration of sensor networks, IoT and Cloud computing, massive and intelligent querying and processing of data. As a result, the book presents lessons learned so far and identifies new research issues, challenges and opportunities for further research and development agendas. Emerging areas of applications are also identified and usefulness of inter-cooperative collective intelligence is envisaged.   Researchers, software developers, practitioners and students interested in the field of inter-cooperative collective intelligence will find the comprehensive coverage of this book useful for their research, academic...

  15. An Experiential Survey on Image Mining Tools, Techniques and Applications

    Directory of Open Access Journals (Sweden)

    C. Lakshmi Devasena,

    2011-03-01

    Full Text Available Digitization in every sector leads to the growth of digital data in a tremendous amount. Digital data are not only available in the form of text but it is also available in the form of images, audio andvideo. Decision making people in every field like business, public sector, hospital, etc. are trying to get useful and implicit information from the already existing digital data bases. Image mining is the concept used to extract implicit and useful data from images stored in the large data bases. Image mining is used in variety of fields like medical diagnosis, space research, remote sensing, agriculture, industries and even in the educational field. This paper elaborates the research works already done in image mining and also summarizes different tool developed, algorithms emerged and the applications of image mining used to extract the useful images in various fields.

  16. Digital microfluidics: A promising technique for biochemical applications

    Science.gov (United States)

    Wang, He; Chen, Liguo; Sun, Lining

    2017-07-01

    Digital microfluidics (DMF) is a versatile microfluidics technology that has significant application potential in the areas of automation and miniaturization. In DMF, discrete droplets containing samples and reagents are controlled to implement a series of operations via electrowetting-on-dielectric. This process works by applying electrical potentials to an array of electrodes coated with a hydrophobic dielectric layer. Unlike microchannels, DMF facilitates precise control over multiple reaction processes without using complex pump, microvalve, and tubing networks. DMF also presents other distinct features, such as portability, less sample consumption, shorter chemical reaction time, flexibility, and easier combination with other technology types. Due to its unique advantages, DMF has been applied to a broad range of fields (e.g., chemistry, biology, medicine, and environment). This study reviews the basic principles of droplet actuation, configuration design, and fabrication of the DMF device, as well as discusses the latest progress in DMF from the biochemistry perspective.

  17. Resolving flows around black holes: numerical technique and applications

    CERN Document Server

    Curtis, Michael

    2015-01-01

    Black holes are believed to be one of the key ingredients of galaxy formation models, but it has been notoriously challenging to simulate them due to the very complex physics and large dynamical range of spatial scales involved. Here we address significant shortcomings of a Bondi-Hoyle-like prescription commonly invoked to estimate black hole accretion in cosmological hydrodynamic simulations of galaxy formation. We describe and implement a novel super-Lagrangian refinement scheme to increase, adaptively and 'on the fly', the mass and spatial resolution in targeted regions around the accreting black holes at limited computational cost. While our refinement scheme is generically applicable and flexible, for the purpose of this paper we select the smallest resolvable scales to match black holes' instantaneous Bondi radii, thus effectively resolving Bondi-Hoyle-like accretion in full galaxy formation simulations. This permits us to not only estimate gas properties close to the Bondi radius much more accurately, ...

  18. Acoustical Characteristics of Mastication Sounds: Application of Speech Analysis Techniques

    Science.gov (United States)

    Brochetti, Denise

    Food scientists have used acoustical methods to study characteristics of mastication sounds in relation to food texture. However, a model for analysis of the sounds has not been identified, and reliability of the methods has not been reported. Therefore, speech analysis techniques were applied to mastication sounds, and variation in measures of the sounds was examined. To meet these objectives, two experiments were conducted. In the first experiment, a digital sound spectrograph generated waveforms and wideband spectrograms of sounds by 3 adult subjects (1 male, 2 females) for initial chews of food samples differing in hardness and fracturability. Acoustical characteristics were described and compared. For all sounds, formants appeared in the spectrograms, and energy occurred across a 0 to 8000-Hz range of frequencies. Bursts characterized waveforms for peanut, almond, raw carrot, ginger snap, and hard candy. Duration and amplitude of the sounds varied with the subjects. In the second experiment, the spectrograph was used to measure the duration, amplitude, and formants of sounds for the initial 2 chews of cylindrical food samples (raw carrot, teething toast) differing in diameter (1.27, 1.90, 2.54 cm). Six adult subjects (3 males, 3 females) having normal occlusions and temporomandibular joints chewed the samples between the molar teeth and with the mouth open. Ten repetitions per subject were examined for each food sample. Analysis of estimates of variation indicated an inconsistent intrasubject variation in the acoustical measures. Food type and sample diameter also affected the estimates, indicating the variable nature of mastication. Generally, intrasubject variation was greater than intersubject variation. Analysis of ranks of the data indicated that the effect of sample diameter on the acoustical measures was inconsistent and depended on the subject and type of food. If inferences are to be made concerning food texture from acoustical measures of mastication

  19. Continuation of Development and Application of Data Processing Techniques and Analytic Procedures to Cloud Physics Data.

    Science.gov (United States)

    1976-07-30

    aircraft is fully explained. Practical applications of various mathematical techniques (such as: Newton’s forward formula, least square curve fitting, Pappus-Guldinus Theorem etc) are fully delineated. (Author)

  20. Application and evaluation of improved surgical aseptic technique curriculum in specialty nurse training in Henan Province

    Directory of Open Access Journals (Sweden)

    Bing Bai

    2016-09-01

    Conclusion: Novel surgical aseptic technique and application in the curriculum design of training for OR nurses should be developed to enhance their mastery of theoretical and practical skills and to modify their behaviors.

  1. Modern Radar Techniques for Geophysical Applications: Two Examples

    Science.gov (United States)

    Arokiasamy, B. J.; Bianchi, C.; Sciacca, U.; Tutone, G.; Zirizzotti, A.; Zuccheretti, E.

    2005-01-01

    The last decade of the evolution of radar was heavily influenced by the rapid increase in the information processing capabilities. Advances in solid state radio HF devices, digital technology, computing architectures and software offered the designers to develop very efficient radars. In designing modern radars the emphasis goes towards the simplification of the system hardware, reduction of overall power, which is compensated by coding and real time signal processing techniques. Radars are commonly employed in geophysical radio soundings like probing the ionosphere; stratosphere-mesosphere measurement, weather forecast, GPR and radio-glaciology etc. In the laboratorio di Geofisica Ambientale of the Istituto Nazionale di Geofisica e Vulcanologia (INGV), Rome, Italy, we developed two pulse compression radars. The first is a HF radar called AIS-INGV; Advanced Ionospheric Sounder designed both for the purpose of research and for routine service of the HF radio wave propagation forecast. The second is a VHF radar called GLACIORADAR, which will be substituting the high power envelope radar used by the Italian Glaciological group. This will be employed in studying the sub glacial structures of Antarctica, giving information about layering, the bed rock and sub glacial lakes if present. These are low power radars, which heavily rely on advanced hardware and powerful real time signal processing. Additional information is included in the original extended abstract.

  2. Applicability of three-dimensional imaging techniques in fetal medicine

    Energy Technology Data Exchange (ETDEWEB)

    Werner Junior, Heron; Daltro, Pedro; Gasparetto, Emerson Leandro, E-mail: heronwerner@hotmail.com [Clinica de Diagnostico Por Imagem (CDPI), Rio de Janeiro, RJ (Brazil); Santos, Jorge Lopes dos; Belmonte, Simone; Ribeiro, Gerson [Pontificia Universidade Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil); Marchiori, Edson [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil)

    2016-09-15

    Objective: To generate physical models of fetuses from images obtained with three-dimensional ultrasound (3D-US), magnetic resonance imaging (MRI), and, occasionally, computed tomography (CT), in order to guide additive manufacturing technology. Materials and Methods: We used 3D-US images of 31 pregnant women, including 5 who were carrying twins. If abnormalities were detected by 3D-US, both MRI and in some cases CT scans were then immediately performed. The images were then exported to a workstation in DICOM format. A single observer performed slice-by-slice manual segmentation using a digital high resolution screen. Virtual 3D models were obtained from software that converts medical images into numerical models. Those models were then generated in physical form through the use of additive manufacturing techniques. Results: Physical models based upon 3D-US, MRI, and CT images were successfully generated. The postnatal appearance of either the aborted fetus or the neonate closely resembled the physical models, particularly in cases of malformations. Conclusion: The combined use of 3D-US, MRI, and CT could help improve our understanding of fetal anatomy. These three screening modalities can be used for educational purposes and as tools to enable parents to visualize their unborn baby. The images can be segmented and then applied, separately or jointly, in order to construct virtual and physical 3D models. (author)

  3. Applicability of three-dimensional imaging techniques in fetal medicine*

    Science.gov (United States)

    Werner Júnior, Heron; dos Santos, Jorge Lopes; Belmonte, Simone; Ribeiro, Gerson; Daltro, Pedro; Gasparetto, Emerson Leandro; Marchiori, Edson

    2016-01-01

    Objective To generate physical models of fetuses from images obtained with three-dimensional ultrasound (3D-US), magnetic resonance imaging (MRI), and, occasionally, computed tomography (CT), in order to guide additive manufacturing technology. Materials and Methods We used 3D-US images of 31 pregnant women, including 5 who were carrying twins. If abnormalities were detected by 3D-US, both MRI and in some cases CT scans were then immediately performed. The images were then exported to a workstation in DICOM format. A single observer performed slice-by-slice manual segmentation using a digital high resolution screen. Virtual 3D models were obtained from software that converts medical images into numerical models. Those models were then generated in physical form through the use of additive manufacturing techniques. Results Physical models based upon 3D-US, MRI, and CT images were successfully generated. The postnatal appearance of either the aborted fetus or the neonate closely resembled the physical models, particularly in cases of malformations. Conclusion The combined use of 3D-US, MRI, and CT could help improve our understanding of fetal anatomy. These three screening modalities can be used for educational purposes and as tools to enable parents to visualize their unborn baby. The images can be segmented and then applied, separately or jointly, in order to construct virtual and physical 3D models. PMID:27818540

  4. Micro-oxygenation of red wine: techniques, applications, and outcomes.

    Science.gov (United States)

    Schmidtke, Leigh M; Clark, Andrew C; Scollary, Geoff R

    2011-02-01

    Wine micro-oxygenation (MOX) is the controlled addition of oxygen to wine in a manner designed to ensure that complete mass transfer of molecular oxygen from gaseous to dissolved state occurs. MOX was initially developed to improve the body, structure, and fruitfulness in red wines with high concentrations of tannins and anthocyanins, by replicating the ingress of oxygen thought to arise from barrel maturation, but without the need for putting all wine to barrel. This review describes the operational parameters essential for the effective performance of the micro-oxidation process as well as the chemical and microbiological outcomes. The methodologies for introducing oxygen into the wine, the rates of oxygen addition, and their relationship to oxygen solubility in the wine matrix are examined. The review focuses on the techniques used for monitoring the MOX process, including sensory assessment, physicochemical properties, and the critical balance of the rate of oxygen addition in relation to maintaining the sulfur dioxide concentration. The chemistry of oxygen reactivity with wine components, the changes in wine composition that occur as a consequence of MOX, and the potential for wine spoilage if proper monitoring is not adopted are examined. Gaps in existing knowledge are addressed focusing on the limitations associated with the transfer of concepts from research trials in small volume tanks to commercial practice, and the dearth of kinetic data for the various chemical and physical processes that are claimed to occur during MOX.

  5. Application of soil-stratigraphic techniques to engineering geology

    Energy Technology Data Exchange (ETDEWEB)

    Shlemon, R.J.

    1985-05-01

    Soil-stratigraphic techniques are being increasingly applied to engineeringgeological investigations for siting liquified natural gas (LNG) facilities, nuclear reactors, dams, and other critical structures. Soil (pedological) profiles in Quaternary sections are useful to ascertain the approximate age of sitearea sediments, to reconstruct local geomorphic history, to date the last movement of faults, and in some cases to determine recurrence intervals of displacements associated with faults or large mass-movements. Exemplified in geotechnical investigations for a proposed LNG terminal near Point Conception (Little Cojo Bay), California, soil stratigraphy was employed to date last displacement of site-area faults, to estimate age of marine platforms, and to help reconstruct regional geomorphic history. Similarly, at the General Electric Test Reactor (GETR) site near Livermore (Vallecitos), California, soil stratigraphy was instrumental to date last displacement and recurrence of site-area slip surfaces engendered either by tectonic or by mass-wasting processes. Datable markers included four, strongly-developed buried paleosols, each of which marked epochs of regional landscape stability during the Quaternary.

  6. Applicability of three-dimensional imaging techniques in fetal medicine

    Directory of Open Access Journals (Sweden)

    Heron Werner Júnior

    Full Text Available Abstract Objective: To generate physical models of fetuses from images obtained with three-dimensional ultrasound (3D-US, magnetic resonance imaging (MRI, and, occasionally, computed tomography (CT, in order to guide additive manufacturing technology. Materials and Methods: We used 3D-US images of 31 pregnant women, including 5 who were carrying twins. If abnormalities were detected by 3D-US, both MRI and in some cases CT scans were then immediately performed. The images were then exported to a workstation in DICOM format. A single observer performed slice-by-slice manual segmentation using a digital high resolution screen. Virtual 3D models were obtained from software that converts medical images into numerical models. Those models were then generated in physical form through the use of additive manufacturing techniques. Results: Physical models based upon 3D-US, MRI, and CT images were successfully generated. The postnatal appearance of either the aborted fetus or the neonate closely resembled the physical models, particularly in cases of malformations. Conclusion: The combined use of 3D-US, MRI, and CT could help improve our understanding of fetal anatomy. These three screening modalities can be used for educational purposes and as tools to enable parents to visualize their unborn baby. The images can be segmented and then applied, separately or jointly, in order to construct virtual and physical 3D models.

  7. Domain-driven specification techniques simplify the analysis of requirements for the KAON factory central control system

    Energy Technology Data Exchange (ETDEWEB)

    Inwood, C. (Inwood Real-Time Systems Associates, Kinburn, ON (Canada)); Ludgate, G.A.; Dohan, D.A.; Osberg, E.A.; Koscielniak, S. (British Columbia Univ., Vancouver (Canada). TRIUMF Facility)

    1990-08-01

    Domain-driven modelling, outlined in this paper, has been successfully applied to the analysis, specification and design of the KAON Factory central control system (KF-CCS). This advanced object-oriented technique is especially suited to the development of complex systems. Early in the project, four very natural domains were identified which simplified the analysis of requirements. (orig.).

  8. Domain-driven specification techniques simplify the analysis of requirements for the Kaon Factory central control system

    Science.gov (United States)

    Inwood, Clifford; Ludgate, G. A.; Dohan, D. A.; Osberg, E. A.; Koscielniak, S.

    1990-08-01

    Domain-driven modelling, outlined in this paper, has been successfully applied to the analysis, specification and design of the KAON Factory central control system (KF-CCS). This advanced object-oriented technique is especially suited to the development of complex systems. Early in the project, four very natural domains were identified which simplified the analysis of requirements.

  9. Techniques and applications for binaural sound manipulation in human-machine interfaces

    Science.gov (United States)

    Begault, Durand R.; Wenzel, Elizabeth M.

    1992-01-01

    The implementation of binaural sound to speech and auditory sound cues (auditory icons) is addressed from both an applications and technical standpoint. Techniques overviewed include processing by means of filtering with head-related transfer functions. Application to advanced cockpit human interface systems is discussed, although the techniques are extendable to any human-machine interface. Research issues pertaining to three-dimensional sound displays under investigation at the Aerospace Human Factors Division at NASA Ames Research Center are described.

  10. Numerical techniques for electromagnetic applications in microelectronic and radar imaging systems

    Science.gov (United States)

    Akerson, Jerome J.

    1998-12-01

    In this thesis, the application of numerical techniques to electromagnetic problems in microelectronic and radar imaging systems are investigated. In particular the following problems are studied: (1) Dielectric rib waveguide discontinuities are analyzed with the Finite Difference Time Domain (FDTD) method. The application of Berenger's Perfectly Matched Layer to multi-layered dielectrics is analyzed and the specific conditions needed to successfully match the multiple dielectric layers are determined and justified. An FDTD method to find the fundamental mode's spatial distribution is used to excite the discontinuity problem. It is shown that the computational domain can be reduced by twenty percent over Gaussian excitations. The effects of rib waveguide bend discontinuities and the effects of the rib geometry to the bend loss are presented. (2) An Impedance Boundary Condition (IBC) for two dimensional FDTD simulations containing thin, good conductor sheets is developed. The IBC uses a recursive convolution scheme based on approximating the conductor's impedance as a sum of exponentials. The effects of FDTD parameters such as grid size and time step on simulation accuracy are presented. The IBC is shown to accurately model the conductor loss over a wide frequency range. The verification is performed by comparing the quality factors of rectangular resonant structures determined by the FDTD simulation and analytical methods. (3) Phase unwrapping techniques for the inversion of terrain height using Synthetic Aperture Radar Interferometry (InSAR) data are analyzed. The weighted least squares and branch cut phase unwrapping techniques are specifically studied. An optimal branch cut method and a hybrid least squares/branch cut method are presented and used to unwrap the phase of both simulated and real SAR interferograms. When used to invert terrain height, these new SAR phase unwrapping methods offer over fifty percent reduction in root mean square (rms) height error

  11. Applications of non-standard maximum likelihood techniques in energy and resource economics

    Science.gov (United States)

    Moeltner, Klaus

    Two important types of non-standard maximum likelihood techniques, Simulated Maximum Likelihood (SML) and Pseudo-Maximum Likelihood (PML), have only recently found consideration in the applied economic literature. The objective of this thesis is to demonstrate how these methods can be successfully employed in the analysis of energy and resource models. Chapter I focuses on SML. It constitutes the first application of this technique in the field of energy economics. The framework is as follows: Surveys on the cost of power outages to commercial and industrial customers usually capture multiple observations on the dependent variable for a given firm. The resulting pooled data set is censored and exhibits cross-sectional heterogeneity. We propose a model that addresses these issues by allowing regression coefficients to vary randomly across respondents and by using the Geweke-Hajivassiliou-Keane simulator and Halton sequences to estimate high-order cumulative distribution terms. This adjustment requires the use of SML in the estimation process. Our framework allows for a more comprehensive analysis of outage costs than existing models, which rely on the assumptions of parameter constancy and cross-sectional homogeneity. Our results strongly reject both of these restrictions. The central topic of the second Chapter is the use of PML, a robust estimation technique, in count data analysis of visitor demand for a system of recreation sites. PML has been popular with researchers in this context, since it guards against many types of mis-specification errors. We demonstrate, however, that estimation results will generally be biased even if derived through PML if the recreation model is based on aggregate, or zonal data. To countervail this problem, we propose a zonal model of recreation that captures some of the underlying heterogeneity of individual visitors by incorporating distributional information on per-capita income into the aggregate demand function. This adjustment

  12. Identifying fly puparia by clearing technique: application to forensic entomology.

    Science.gov (United States)

    Sukontason, Kabkaew L; Ngern-Klun, Radchadawan; Sripakdee, Duanghatai; Sukontason, Kom

    2007-10-01

    In forensic investigations, immature stages of the fly (egg, larva, or puparia) can be used as entomological evidence at death scenes, not only to estimate the postmortem interval (PMI), analyze toxic substances, and to determine the manner of death but also to indicate the movement of a corpse in homicide cases. Of these immature stages, puparia represent the longest developmental time, which makes them of useful. However, in order for forensic entomologists to use puparia effectively, it is crucial that they are able to accurately identify the species of fly found in a corpse. Typically, these puparia are similar in general appearance, being coarctate and light brown to dark brown in color, which makes identification difficult. In this study, we report on the clearing technique used to pale the integument of fly puparia, thereby allowing observation of the anterior end (second to fourth segments) and the profile of the posterior spiracle, which are important clues for identification. We used puparia of the blowfly, Chrysomya megacephala (F.), as the model species in this experiment. With placement in a 20% potassium hydroxide solution daily and mounting on a clearing medium (Permount(R), New Jersey), the profile of the posterior spiracle could be clearly examined under a light microscope beginning on the fifth day after pupation, and the number of papillae in the anterior spiracle could be counted easily starting from the ninth day. Comparison of morphological features of C. megacephala puparia with those of other blowflies (Chrysomya nigripes [Aubertin], Chrysomya rufifacies [Macquart], Chrysomya villeneuvi [Patton], Lucilia cuprina [Wiedemann], and Hemipyrellia ligurriens [Wiedemann]) and a housefly (Musca domestica L.) revealed that the anterior ends and the profiles of the posterior spiracles had markedly distinguishing characteristics. Morphometric analysis of the length and width of puparia, along with the length of the gaps between the posterior spiracles

  13. Application of phaco prechop with phaco chop technique in phacoemulsification

    Directory of Open Access Journals (Sweden)

    Wei Liu

    2014-03-01

    Full Text Available AIM:To compare two phaco techniques, namely phaco prechop with phaco chop and divide and conquer, and to discuss the technical advantages of phaco prechop with phaco chop METHODS:The study included 131 patients(156 eyeswith age-related cataract eyes divided into 2 groups, group A including 68 patients(82 eyes, in which phaco prechop with phaco chop was performed, and group B including 63 patients(74 eyes, in which divide and conquer was performed. The mean parameters including average power(AP, U/S time, accumulated energy complex parameter(AECP, mean endothelial cell count, mean endothelial cell loss, intraoperative complications, postoperative uncorrected visual acuity(UCVAat 1d and 1wk, and corneal edema were reported in the two groups both preoperative and postoperative.RESULTS:The subgroups with same grade of lens nucleus hardness were compared. Parameters such as AP, U/S time, AECP in group A were significantly less than those in group B. Postoperative corneal clarity and UCVA at 1d in group A was better than that in group B. No significant difference was found in UCVA at 1wk after operation between the two groups. The difference in mean endothelial cell count at 3mo postoperative between the two groups was statistically insignificant(P>0.05, however the difference in endothelial cell loss at 3mo postoperatively between the two groups was statistically significant(PCONCLUSION:Compare with divide and conquer, phaco prechop with phaco chop utilized less phaco time, energy, and the rate of endothelial cell loss at 3mo postoperatively, and better early postoperative uncorrected visual acuity.

  14. Third Generation Sequencing Techniques and Applications to Drug Discovery

    Science.gov (United States)

    Ozsolak, Fatih

    2012-01-01

    Introduction There is an immediate need for functional and molecular studies to decipher differences between disease and “normal” settings to identify large quantities of validated targets with the highest therapeutic utilities. Furthermore, drug mechanism of action and biomarkers to predict drug efficacy and safety need to be identified for effective design of clinical trials, decreasing attrition rates, regulatory agency approval process and drug repositioning. By expanding the power of genetics and pharmacogenetics studies, next generation nucleic acid sequencing technologies have started to play an important role in all stages of drug discovery. Areas covered This article reviews the first and second generation sequencing technologies (SGSTs) and challenges they pose to biomedicine. The article then focuses on the emerging third generation sequencing technologies (TGSTs), their technological foundations and potential contributions to drug discovery. Expert Opinion Despite the scientific and commercial success of SGSTs, the goal of rapid, comprehensive and unbiased sequencing of nucleic acids has not been achieved. TGSTs promise to increase sequencing throughput and read lengths, decrease costs, run times and error rates, eliminate biases inherent in SGSTs, and offer capabilities beyond nucleic acid sequencing. Such changes will have positive impact in all sequencing applications to drug discovery. PMID:22468954

  15. Applications of discrete multiwavelet techniques to image denoising

    Science.gov (United States)

    Wang, Haihui; Peng, Jiaxiong; Wu, Wei; Ye, Bin

    2003-09-01

    In this paper, we present a new method by using 2-D discrete multiwavelet transform in image denoising. The developments in wavelet theory have given rise to the wavelet thresholding method, for extracting a signal from noisy data. The method of signal denoising via wavelet thresholding was popularized. Multiwavelets have recently been introduced and they offer simultaneous orthogonality, symmetry and short support. This property makes multiwavelets more suitable for various image processing applications, especially denoising. It is based on thresholding of multiwavelet coefficients arising from the standard scalar orthogonal wavelet transform. It takes into account the covariance structure of the transform. Denoising is images via thresholding of the multiwavelet coefficients result from preprocessing and the discrete multiwavelet transform can be carried out by threating the output in this paper. The form of the threshold is carefully formulated and is the key to the excellent results obtained in the extensive numerical simulations of image denoising. The performances of multiwavelets are compared with those of scalar wavelets. Simulations reveal that multiwavelet based image denoising schemes outperform wavelet based method both subjectively and objectively.

  16. Application of lightweight threading techniques to computational chemistry

    Science.gov (United States)

    Thornley, John; Muller, Richard P.; Mainz, Daniel T.; Çağin, Tahir; Goddard, William A.

    2001-05-01

    The recent advent of inexpensive commodity multiprocessor computers with standardized operating system support for lightweight threads provides computational chemists and other scientists with an exciting opportunity to develop sophisticated new approaches to materials simulation. We contrast the flexible performance characteristics of lightweight threading with the restrictions of traditional scientific supercomputing, based on our experiences with multithreaded molecular dynamics simulation. Motivated by the results of our molecular dynamics experiments, we propose an approach to multi-scale materials simulation using highly dynamic thread creation and synchronization within and between concurrent simulations at many different scales. This approach will enable extremely realistic simulations, with computing resources dynamically directed to areas where they are needed. Multi-scale simulations of this kind require large amounts of processing power, but are too sophisticated to be expressed using traditional supercomputing programming models. As a result, we have developed a high-level programming system called Sthreads that allows highly dynamic, nested multithreaded algorithms to be expressed. Program development is simplified through the use of innovative synchronization operations that allow multithreaded programs to be tested and debugged using standard sequential methods and tools. For this reason, Sthreads is very well suited to the complex multi-scale simulation applications that we are developing.

  17. Operation placement for application-specific digital microfluidic biochips

    DEFF Research Database (Denmark)

    Alistar, Mirela; Pop, Paul; Madsen, Jan

    2013-01-01

    Microfluidic-based biochips are replacing the conventional biochemical analyzers, and are able to integrate onchip all the necessary functions for biochemical analysis using microfluidics. The digital microfluidic biochips are based on the manipulation of liquids not as a continuous flow, but as ......, such that the application completion time is minimized. The proposed algorithm has been evaluated using several benchmarks.......Microfluidic-based biochips are replacing the conventional biochemical analyzers, and are able to integrate onchip all the necessary functions for biochemical analysis using microfluidics. The digital microfluidic biochips are based on the manipulation of liquids not as a continuous flow......, but as discrete droplets on an array of electrodes. Microfluidic operations, such as transport, mixing, split, are performed on this array by routing the corresponding droplets on a series of electrodes. Researchers have proposed several approaches for the synthesis of digital microfluidic biochips. All previous...

  18. High Performance Computing - Power Application Programming Interface Specification.

    Energy Technology Data Exchange (ETDEWEB)

    Laros, James H.,; Kelly, Suzanne M.; Pedretti, Kevin; Grant, Ryan; Olivier, Stephen Lecler; Levenhagen, Michael J.; DeBonis, David

    2014-08-01

    Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area [13, 3, 5, 10, 4, 21, 19, 16, 7, 17, 20, 18, 11, 1, 6, 14, 12]. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover the entire software space, from generic hardware interfaces to the input from the computer facility manager.

  19. Applications of NLP Techniques to Computer-Assisted Authoring of Test Items for Elementary Chinese

    Science.gov (United States)

    Liu, Chao-Lin; Lin, Jen-Hsiang; Wang, Yu-Chun

    2010-01-01

    The authors report an implemented environment for computer-assisted authoring of test items and provide a brief discussion about the applications of NLP techniques for computer assisted language learning. Test items can serve as a tool for language learners to examine their competence in the target language. The authors apply techniques for…

  20. Novel applications of optical techniques to the study of buried semiconductor interfaces

    Science.gov (United States)

    Wilson, Barbara A.

    1989-01-01

    Detailed electronic and structural information about buried semiconductor interfaces obtained through application of optical techniques is discussed. The measurements described include the determination of band discontinuities, strain, and disorder associated with semiconductor heterointerfaces. The contactless and nondestructive nature of these optical techniques is particularly important for the study of heterointerfaces which are inherently inaccessible to direct electrical or physical contact.

  1. Clinical Application and Characteristics of KONG's Scalp Acupuncture and Daoyin Technique

    Institute of Scientific and Technical Information of China (English)

    JIANG Ling-zhen; XIAO Yuan-chun

    2004-01-01

    @@ Scalp Acupuncture and Daoyin Technique, which are summarized by Dr. KONG in the light of his long-term acupuncture practice, has been considered as one of the clinical diagnostic and treatment programs in Chinese medicine by the State Administration of Traditional Chinese Medicine. In this paper, the characteristics and clinical application of Scalp Acupuncture and Daoyin Technique are presented as follows.

  2. [Western blot technique standardization for specific diagnosis of Chagas disease using excretory-secretory antigens of Trypanosoma cruzi epimastigotes].

    Science.gov (United States)

    Escalante, Hermes; Jara, César; Davelois, Kelly; Iglesias, Miguel; Benites, Adderly; Espinoza, Renzo

    2014-01-01

    Evaluate the effectiveness of Western Blot for the specific diagnosis of Chagas disease using excretory-secretory antigens of Trypanosoma cruzi epimastigotes. Antigens were obtained after twenty hours of incubation in Eagle’s Minimum Essential Medium, which were prepared at a protein concentration of 0.2 ug/uL to be faced with 10 mL pool of serum from patients with Chagas disease and a conjugated anti-IgG labeled with peroxidase. The presence of the following antigens was observed: 10, 12, 14, 15, 19, 20, 23, 26, 30, 33, 36, 40, 42, 46, 58, 63, 69, 91, 100, and 112 kDa; of which antigens of 10, 12, 14, 15, 19, 20, 23, and 26 kDa were considered to be specific using pools of serum from patients with other parasitosis and serum from people with no parasites. The sensitivity of the technique was assessed using individual serum from 65 patients with Chagas disease; and the specificity with serum from 40 patients with other parasitosis, and serums from five people who did not have parasites. The technique has a sensitivity of 95.4% in the detection of one to eight specific bands, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 93.7%. Western Blot technique with excretory-secretory antigens of T. cruzi epimastigotes is effective in the diagnosis of Chagas disease in Peru; therefore, it can be used as a confirmatory test.

  3. Selected applications of photothermal and photoluminescence heterodyne techniques for process control in silicon wafer manufacturing

    Science.gov (United States)

    Ehlert, Andreas; Kerstan, Michael; Lundt, Holger; Huber, Anton; Helmreich, Dieter; Geiler, Hans-Dieter; Karge, Harald; Wagner, Matthias

    1997-02-01

    Two noncontact laser-based heterodyne techniques, photothermal heterodyne (PTH) and photoluminescence heterodyne (PLH), are introduced and applied to processing and quality control in silicon wafer manufacturing. The crystallographic characteristics of process-induced defects in silicon wafers are suitable for the application of PTH and PLH techniques, which are demonstrated on selected examples from different steps of silicon wafer production. Both PLH and PTH techniques meet the demand for nondestructive and on-line-suitable measurement in the semiconductor industry.

  4. Actinide-specific sequestering agents and decontamination applications

    Energy Technology Data Exchange (ETDEWEB)

    Smith, William L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials and Molecular Research Division; Univ. of California, Berkeley, CA (United States). Dept. of Chemistry; Raymond, Kenneth N. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials and Molecular Research Division; Univ. of California, Berkeley, CA (United States). Dept. of Chemistry

    1981-04-07

    With the commercial development of nuclear reactors, the actinides have become very important industrial elements. A major concern of the nuclear industry is the biological hazard associated with nuclear fuels and their wastes. The acute chemical toxicity of tetravalent actinides, as exemplified by Th(IV), is similar to Cr(III) or Al(III). However, the acute toxicity of 239Pu(IV) is similar to strychnine, which is much more toxic than any of the non-radioactive metals such as mercury. Although the more radioactive isotopes of the transuranium elements are more acutely toxic by weight than plutonium, the acute toxicities of 239Pu, 241Am, and 244Cm are nearly identical in radiation dose, ~100 μCi/kg in rodents. Finally and thus, the extreme acute toxicity of 239Pu is attributed to its high specific activity of alpha emission.

  5. Knowledge elicitation techniques and application to nuclear plant maintenance

    Science.gov (United States)

    Doyle, E. Kevin

    The new millennium has brought with it the opportunity of global trade which in turn requires the utmost in efficiency from each individual industry. This includes the nuclear power industry, a point which was emphasized when the electrical generation industry began to be de regulated across North America the late 1990s and re-emphasized when the northeast power grid of North America collapsed in the summer of 2003. This dissertation deals with reducing the cost of the maintenance function of Candu nuclear power plants and initiating a strong link between universities and the Canadian nuclear industry. Various forms of RCM (reliability-centred maintenance) have been the tools of choice in industry for improving the maintenance function during the last 20 years. In this project, pilot studies, conducted at Bruce Power between 1999 and 2005, and reported on in this dissertation, lay out a path to implement statistical improvements as the next step after RCM in reducing the cost of the maintenance. Elicitation protocols, designed for the age group being elicited, address the much-documented issue of a lack of data. Clear, graphical, inferential statistical interfaces are accentuated and developed to aid in building the teams required to implement the various methodologies and to help in achieving funding targets. Graphical analysis and Crow/AMSAA (army materials systems analysis activity) plots are developed and demonstrated from the point of view of justifying the expenditures of cost reduction efforts. This dissertation ultimately speaks to the great opportunity being presented by this approach at this time: of capturing the baby-boom generation's huge pool of knowledge before those people retire. It is expected that the protocols and procedures referenced here will have applicability across the many disciplines where collecting expert information from a similar age group is required.

  6. Application of experimental and numerical simulation techniques to microscale devices

    Science.gov (United States)

    Somashekar, Vishwanath

    flow regime was observed at Reynolds number of 25 whereas the flow was turbulent at Reynolds numbers of 1000 and 1500. An image processing technique was applied to instantaneous images to extract quantitative mixing data by identifying regions with pH ≥ 9.3 and regions with pH < 9.3. The ensemble-averages were computed using these thresholded images to compare mixing performance between different Reynolds numbers. Finally, the spatial auto-correlation fields of the thresholded images fluctuations were evaluated, based on which large-scale turbulent structure were analyzed.

  7. Application techniques of coatings by thermal projection; Tecnicas de aplicacion de recubrimientos por proyeccion termica

    Energy Technology Data Exchange (ETDEWEB)

    Porcayo Calderon, Jesus [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1995-12-31

    The coatings applied by thermal projection have an important number of applications in different industries (chemical, oil, electric, nuclear, etc.). The main purpose of the protection by means of coatings is to alter the surface characteristics of a component so as to resist corrosive environments, abrasion and erosion, among others. The coatings can be applied by different methods, but due to the fact that its characteristics appreciably differ from the base metal, it is important the knowledge of its properties when a coating is selected for a specific use. In this article the characteristics of the applied coatings by thermal projection, the factors that affect its performance and the principal application techniques, are described. [Espanol] Los recubrimientos aplicados por proyeccion termica tienen un numero importante de aplicaciones en diferentes industrias (quimica, petrolera, electrica, nuclear, etc.). El proposito principal de la proteccion por medio de recubrimientos es alterar las caracteristicas de la superficie de un componente de manera que resista ambientes corrosivos, abrasion y erosion, entre otros. Los recubrimientos pueden aplicarse por diferentes metodos, pero debido a que sus propiedades difieren apreciablemente de las del metal base, es importante el conocimiento de sus propiedades cuando se selecciona un recubrimiento para un uso especifico. En este articulo se describen las caracteristicas de los recubrimientos aplicados por proyeccion termica, los factores que afectan su desempeno y las principales tecnicas de aplicacion.

  8. Application and further development of diffusion based 2D chemical imaging techniques in the rhizosphere

    Science.gov (United States)

    Hoefer, Christoph; Santner, Jakob; Borisov, Sergey; Kreuzeder, Andreas; Wenzel, Walter; Puschenreiter, Markus

    2015-04-01

    Two dimensional chemical imaging of root processes refers to novel in situ methods to investigate and map solutes at a high spatial resolution (sub-mm). The visualization of these solutes reveals new insights in soil biogeochemistry and root processes. We derive chemical images by using data from DGT-LA-ICP-MS (Diffusive Gradients in Thin Films and Laser Ablation Inductively Coupled Plasma Mass Spectrometry) and POS (Planar Optode Sensors). Both technologies have shown promising results when applied in aqueous environment but need to be refined and improved for imaging at the soil-plant interface. Co-localized mapping using combined DGT and POS technologies and the development of new gel combinations are in our focus. DGTs are smart and thin (images of the target area are plotted using imaging software. POS are, similar to DGT, thin sensor foils containing a fluorophore coating depending on the target analyte. The measurement principle is based on excitation of the flourophore by a specific wavelength and emission of the fluorophore depending on the presence of the analyte. The emitted signal is captured using optical filters and a DSLR camera. While DGT analysis is destructive, POS measurements can be performed continuously during the application. Both semi-quantitative techniques allow an in situ application to visualize chemical processes directly at the soil-plant interface. Here, we present a summary of results from rhizotron experiments with different plants in metal contaminated and agricultural soils.

  9. Selective Chemical-Lithographic Reaction Techniques Using Radiation Technology for Biological Application

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Kwan Woo; Kim, Keo Su; Kim, Hyun Jung; Kim, Hee Suk; Lee, Mi Jin [Sogang University, Seoul (Korea, Republic of)

    2010-05-15

    This report, titled 'selective Chemical-Lithographic Reaction Techniques Using Radiation Technology for Biological Application' contains a research summary, 1) development of selective reaction technology using irradiation of electron beams, 2) preparation of functional surfaces using selective radiation technology on carbon-based nanomaterials, and 3) development of bio-applicable biochips using combinatorial surface modification

  10. Technique development of PC104 embedded module and its application in the geophysical instrument design

    Institute of Scientific and Technical Information of China (English)

    滕云田; 张炼; 王彦; 刘晓芹; 马延妮

    2002-01-01

    The mainstream embedded resolutions widely adopted in the geophysical observation device are discussed in this paper. The advantages and its applicability of the PC104 embedded module are demonstrated through its performance description, technique development and its applications in the design of the fluxgate magnetometer, the movable seismograph and the GPS steering device.

  11. Review on Sol-Gel Derived Coatings:Process, Techniques and Optical Applications

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Sol-gel process is one of the simplest techniques to manufacture thin films. The quality of the prepared films depends on the parameters of the sol-gel process and the used technique for deposition. A great variety of the sol-gel derived films have been prepared for different applications. We present a review on the sol-gel derived coatings. The description of the process is introduced in details. Different sol-gel deposition techniques are mentioned. The optical applications of the sol-gel derived coatings are reviewed.

  12. The application of emulation techniques in the analysis of highly reliable, guidance and control computer systems

    Science.gov (United States)

    Migneault, Gerard E.

    1987-01-01

    Emulation techniques can be a solution to a difficulty that arises in the analysis of the reliability of guidance and control computer systems for future commercial aircraft. Described here is the difficulty, the lack of credibility of reliability estimates obtained by analytical modeling techniques. The difficulty is an unavoidable consequence of the following: (1) a reliability requirement so demanding as to make system evaluation by use testing infeasible; (2) a complex system design technique, fault tolerance; (3) system reliability dominated by errors due to flaws in the system definition; and (4) elaborate analytical modeling techniques whose precision outputs are quite sensitive to errors of approximation in their input data. Use of emulation techniques for pseudo-testing systems to evaluate bounds on the parameter values needed for the analytical techniques is then discussed. Finally several examples of the application of emulation techniques are described.

  13. Overview of independent component analysis technique with an application to synthetic aperture radar (SAR) imagery processing.

    Science.gov (United States)

    Fiori, Simone

    2003-01-01

    We present an overview of independent component analysis, an emerging signal processing technique based on neural networks, with the aim to provide an up-to-date survey of the theoretical streams in this discipline and of the current applications in the engineering area. We also focus on a particular application, dealing with a remote sensing technique based on synthetic aperture radar imagery processing: we briefly review the features and main applications of synthetic aperture radar and show how blind signal processing by neural networks may be advantageously employed to enhance the quality of remote sensing data.

  14. Three-dimensional radar imaging techniques and systems for near-field applications

    Energy Technology Data Exchange (ETDEWEB)

    Sheen, David M.; Hall, Thomas E.; McMakin, Douglas L.; Jones, Anthony M.; Tedeschi, Jonathan R.

    2016-05-12

    The Pacific Northwest National Laboratory has developed three-dimensional holographic (synthetic aperture) radar imaging techniques and systems for a wide variety of near-field applications. These applications include radar cross-section (RCS) imaging, personnel screening, standoff concealed weapon detection, concealed threat detection, through-barrier imaging, ground penetrating radar (GPR), and non-destructive evaluation (NDE). Sequentially-switched linear arrays are used for many of these systems to enable high-speed data acquisition and 3-D imaging. In this paper, the techniques and systems will be described along with imaging results that demonstrate the utility of near-field 3-D radar imaging for these compelling applications.

  15. Modification-specific proteomics: strategies for characterization of post-translational modifications using enrichment techniques

    DEFF Research Database (Denmark)

    Zhao, Yingming; Jensen, Ole N

    2009-01-01

    substrates and their PTM sites is key to dissection of PTM-mediated cellular processes. The past several years have seen a tremendous progress in developing MS-based proteomics technologies for global PTM analysis, including numerous studies of yeast and other microbes. Modification-specific enrichment...

  16. Methods and Techniques for the Design and Implementation of Domain-Specific Languages

    NARCIS (Netherlands)

    Hemel, Z.

    2012-01-01

    Domain-Specific Languages (DSLs) are programming language aimed at a particular problem domain, e.g. banking, database querying or website page lay-outs. Through the use of high-level concepts, a DSL raises the level of abstraction and expressive power of the programmer, and reduces the size of prog

  17. Methods and Techniques for the Design and Implementation of Domain-Specific Languages

    NARCIS (Netherlands)

    Hemel, Z.

    2012-01-01

    Domain-Specific Languages (DSLs) are programming language aimed at a particular problem domain, e.g. banking, database querying or website page lay-outs. Through the use of high-level concepts, a DSL raises the level of abstraction and expressive power of the programmer, and reduces the size of prog

  18. Using the SCR Specification Technique in a High School Programming Course.

    Science.gov (United States)

    Rosen, Edward; McKim, James C., Jr.

    1992-01-01

    Presents the underlying ideas of the Software Cost Reduction (SCR) approach to requirements specifications. Results of applying this approach to the teaching of programing to high school students indicate that students perform better in writing programs. An appendix provides two examples of how the method is applied to problem solving. (MDH)

  19. Evaluation of a novel technique in airway clearance therapy – Specific Cough Technique (SCT) in cystic fibrosis: A pilot study of a series of N-of-1 randomised controlled trials

    Science.gov (United States)

    Gursli, Sandra; Sandvik, Leiv; Bakkeheim, Egil; Skrede, Bjørn; Stuge, Britt

    2017-01-01

    Objectives: The aim of this pilot study was to evaluate the efficacy, safety and participants’ perception of a novel technique in airway clearance therapy – specific cough technique in cystic fibrosis. Methods: We conducted randomised controlled individual trials (N-of-1 randomised controlled trials) in six adults. Each trial included 8 weeks of treatment with two interventions each week, one with specific cough technique and one with forced expiration technique. The efficacy was investigated by a blinded assessor measuring wet weight of sputum (g) after each session. Perceived usefulness and preference was self-reported at the end of study. Additional measurements included oxygen saturation and heart rate before and after each session and lung function (week 2). Results: Three of six participants produced significantly higher mean sputum weight when using specific cough technique, differences being 21%, 38% and 23%, respectively. In three of the six participants, mean sputum weight was lower after forced expiration technique than after specific cough technique in each of the eight treatment pairs. Participant-reported outcomes were completed in all participants. Specific cough technique was reported to be easier to use in daily treatments and more normalising in everyday life. Conclusion: Specific cough technique was well tolerated and accepted by the participants with cystic fibrosis. Specific cough technique was non-inferior to forced expiration technique in terms of sputum production, thus specific cough technique appears to represent a promising alternative for clearing sputum in airway clearance therapy. PMID:28540046

  20. The Bactrocera dorsalis species complex: comparative cytogenetic analysis in support of Sterile Insect Technique applications.

    Science.gov (United States)

    Augustinos, Antonios A; Drosopoulou, Elena; Gariou-Papalexiou, Aggeliki; Bourtzis, Kostas; Mavragani-Tsipidou, Penelope; Zacharopoulou, Antigone

    2014-01-01

    The Bactrocera dorsalis species complex currently harbors approximately 90 different members. The species complex has undergone many revisions in the past decades, and there is still an ongoing debate about the species limits. The availability of a variety of tools and approaches, such as molecular-genomic and cytogenetic analyses, are expected to shed light on the rather complicated issues of species complexes and incipient speciation. The clarification of genetic relationships among the different members of this complex is a prerequisite for the rational application of sterile insect technique (SIT) approaches for population control. Colonies established in the Insect Pest Control Laboratory (IPCL) (Seibersdorf, Vienna), representing five of the main economic important members of the Bactrocera dorsalis complex were cytologically characterized. The taxa under study were B. dorsalis s.s., B. philippinensis, B. papayae, B. invadens and B. carambolae. Mitotic and polytene chromosome analyses did not reveal any chromosomal characteristics that could be used to distinguish between the investigated members of the B. dorsalis complex. Therefore, their polytene chromosomes can be regarded as homosequential with the reference maps of B. dorsalis s.s.. In situ hybridization of six genes further supported the proposed homosequentiallity of the chromosomes of these specific members of the complex. The present analysis supports that the polytene chromosomes of the five taxa under study are homosequential. Therefore, the use of the available polytene chromosome maps for B. dorsalis s.s. as reference maps for all these five biological entities is proposed. Present data provide important insight in the genetic relationships among the different members of the B. dorsalis complex, and, along with other studies in the field, can facilitate SIT applications targeting this complex. Moreover, the availability of 'universal' reference polytene chromosome maps for members of the complex

  1. Feature Specific Criminal Mapping using Data Mining Techniques and Generalized Gaussian Mixture Model

    OpenAIRE

    Uttam Mande; Y. Srinivas; Murthy, J. V. R.

    2012-01-01

    Lot of research is projected to map the criminal with that of crime and it is observed that there is still a huge increase in the crime rate due to the gap between the optimal usage of technologies and investigation. This has given scope for the development of new methodologies in the area of crime investigation using the techniques based on data mining, image processing, forensic, and social mining. In this paper, presents a model using new methodology for mapping the criminal with the crime...

  2. Specifics of the Activity-Based Costing applications in Hospital Management

    Directory of Open Access Journals (Sweden)

    Boris Popesko

    2013-03-01

    Full Text Available The current paper analyses the specifics of the application of Activity-Based Costing method in hospital management. Primary objective of the paper is to outline the methodology of the ABC application in hospitals. First part of the paper analyzes the ways of ABC implementation in published foreign studies. Second part describes the individual steps in ABC application and discusses the differences in the application procedures between the manufacturing and hospital organization.

  3. Statistical and Managerial Techniques for Six Sigma Methodology Theory and Application

    CERN Document Server

    Barone, Stefano

    2012-01-01

    Statistical and Managerial Techniques for Six Sigma Methodology examines the methodology through illustrating the most widespread tool and techniques involved in Six Sigma application. Both managerial and statistical aspects of Six Sigma will be analyzed, allowing the reader to apply these tools in the field. This book offers an insight on variation and risk management, and focuses on the structure and organizational aspects of the Six Sigma projects. It covers six sigma methodology, basic managerial techniques, basic statistical techniques, methods for variation and risk management and advanc

  4. Recent Progress in Application of Internal Oxidation Technique in Nb3Sn Strands

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Xingchen [Fermilab; Peng, Xuan [Hyper Tech Research Inc.; Sumption, Michael [Ohio State U.; Collings, E. W. [Ohio State U.

    2016-10-13

    The internal oxidation technique can generate ZrO2 nano particles in Nb3Sn strands, which markedly refine the Nb3Sn grain size and boost the high-field critical current density (Jc). This article summarizes recent efforts on implementing this technique in practical Nb3Sn wires and adding Ti as a dopant. It is demonstrated that this technique can be readily incorporated into the present Nb3Sn conductor manufacturing technology. Powder-in-tube (PIT) strands with fine subelements (~25 µm) based on this technique were successfully fabricated, and proper heat treatments for oxygen transfer were explored. Future work for producing strands ready for applications is proposed.

  5. [The application of minisatellite MS31A MVR-PCR digital coding technique in forensic science].

    Science.gov (United States)

    Hou, G

    2000-02-01

    Using isotope incorporate amplification technique of special 31A, 31A-A, 31A-G primers and alpha-32PdCTP, the minisatellite MS31A (located at D7S21 loci) was studied. A rapid, simple, and accurate MVR-PCR technique was successfully established. The technique can be applied in individual identification minutes amples, such as blood stains, semen stains contaminated by vaginal fluid, hair and bones. The sensitivity analysis revealed that this technique could detect 1 ng genoma DNA. It is also discribed about the application of the method in 40 criminal cases of rape and murder.

  6. COMPARISON OF THREE KINESIO TECHNIQUE APPLICATION ON JUMPING IN COLLEGIATE FEMALE ATHLETES

    Directory of Open Access Journals (Sweden)

    Kailash Sharma

    2015-06-01

    Full Text Available Background: Kinesio Tape (KT is a somewhat new type of taping technique gaining popularity as both treatment and performance enhancement tool. Considering the fact that KT can improve muscle performance, however, limited research has been done on the different technique of strips application of KT on functional performance. Therefore purpose of this study is to compare Comparison of three kinesio technique application on jumping in collegiate female athletes. Methods: 45 healthy collegiate female athletes were recruited based on inclusion and exclusion criteria. The subjects were randomly divided into three equal groups (group I, n=15, Group II, n=15 & group III, n=15. Group I received Y application of kinesio taping, Group II received I application of kinesio taping while, Group III underwent combined Y & I application of kinesio tape on triceps surae. Pre and post measurement of vertical jump (in terms of power average, power peak and horizontal distance were documented. Results: Statistically significant differences were found between the difference power average, difference power peak and difference horizontal jump in group I, II and III (p<0.001. Within group comparison also revealed statistically significant differences in power average, power peak and horizontal jump in all the three groups (p<0.001. Conclusion: Combined technique (Y and I application of kinesio was more effective in improving vertical jump (power average, power peak and horizontal jump as compared to Y and I application alone.

  7. Applications of solid state nuclear magnetic resonance techniques to the study of coals and polymers. [Ph. D. thesis; 125 references

    Energy Technology Data Exchange (ETDEWEB)

    Pembleton, R.G.

    1979-01-01

    The use of Nuclear Magnetic Resonance (NMR) to study molecules in the solid state has grown rapidly over the past several years. This is due to the advent of techniques which allow for the removal of certain interactions in the solid state which previously have thwarted most attempts at obtaining chemical shift or their anisotropies. With these parameters and others now available, NMR has become an important tool to be used in the understanding of the chemistry of solids. The work reported in this dissertation applies the techniques of solid state NMR to a number of chemical systems. Specific applications are made to crystallinity in polymers, to combined sample spinning and multiple pulse techniques, and to aromatic and aliphatic content of vitrain portions of coals of varying carbon content.

  8. Improved techniques in data analysis and interpretation of potential fields: examples of application in volcanic and seismically active areas

    Directory of Open Access Journals (Sweden)

    G. Florio

    2002-06-01

    Full Text Available Geopotential data may be interpreted by many different techniques, depending on the nature of the mathematical equations correlating specific unknown ground parameters to the measured data set. The investigation based on the study of the gravity and magnetic anomaly fields represents one of the most important geophysical approaches in the earth sciences. It has now evolved aimed both at improving of known methods and testing other new and reliable techniques. This paper outlines a general framework for several applications of recent techniques in the study of the potential methods for the earth sciences. Most of them are here described and significant case histories are shown to illustrate their reliability on active seismic and volcanic areas.

  9. On the Biomass Specific Growth Rates Estimation for Anaerobic Digestion using Differential Algebraic Techniques

    Directory of Open Access Journals (Sweden)

    Sette Diop

    2009-10-01

    Full Text Available The paper deals with identifiability and observability of anaerobic digestion (AD processes. In such kind of processes, generally carried out in continuously stirred tank bioreactors, the organic matter is depolluted by microorganisms into biogas and compost in the absence of oxygen. The biogas is an additional energy source, which can replace fossil fuel sources. The differential algebraic approach of general observation problems has been applied to investigate the identification and observation of a simple AD model. The major discovery is that the biomass specific growth rate can be stably estimated from easily measured quantities: the dilution rate and the biogas flow rate. Next if the yield coefficients are assumed known then, of course, the biomass concentration is observable. Unfortunately, even under the latter strongest assumption the substrate concentration is not observable. This concentration becomes observable if an additional model, say the Monod model, is assumed for the specific growth rate. Illustrative simulations are presented.

  10. Central neuronal motor behaviour in skilled and less skilled novices - Approaching sports-specific movement techniques.

    Science.gov (United States)

    Vogt, Tobias; Kato, Kouki; Schneider, Stefan; Türk, Stefan; Kanosue, Kazuyuki

    2017-02-14

    Research on motor behavioural processes preceding voluntary movements often refers to analysing the readiness potential (RP). For this, decades of studies used laboratory setups with controlled sports-related actions. Further, recent applied approaches focus on athlete-non-athlete comparisons, omitting possible effects of training history on RP. However, RP preceding real sport-specific movements in accordance to skill acquisition remains to be elucidated. Therefore, after familiarization 16 right-handed males with no experience in archery volunteered to perform repeated sports-specific movements, i.e. 40 arrow-releasing shots at 60s rest on a 15m distant standard target. Continuous, synchronised EEG and right limb EMG recordings during arrow-releasing served to detect movement onsets for RP analyses over distinct cortical motor areas. Based on attained scores on target, archery novices were, a posteriori, subdivided into a skilled and less skilled group. EMG results for mean values revealed no significant changes (all p>0.05), whereas RP amplitudes and onsets differed between groups but not between motor areas. Arrow-releasing preceded larger RP amplitudes (p<0.05) and later RP onsets (p<0.05) in skilled compared to less skilled novices. We suggest this to reflect attentional orienting and greater effort that accompanies central neuronal preparatory states of a sports-specific movement.

  11. Sample Subset Optimization Techniques for Imbalanced and Ensemble Learning Problems in Bioinformatics Applications.

    Science.gov (United States)

    Yang, Pengyi; Yoo, Paul D; Fernando, Juanita; Zhou, Bing B; Zhang, Zili; Zomaya, Albert Y

    2014-03-01

    Data sampling is a widely used technique in a broad range of machine learning problems. Traditional sampling approaches generally rely on random resampling from a given dataset. However, these approaches do not take into consideration additional information, such as sample quality and usefulness. We recently proposed a data sampling technique, called sample subset optimization (SSO). The SSO technique relies on a cross-validation procedure for identifying and selecting the most useful samples as subsets. In this paper, we describe the application of SSO techniques to imbalanced and ensemble learning problems, respectively. For imbalanced learning, the SSO technique is employed as an under-sampling technique for identifying a subset of highly discriminative samples in the majority class. In ensemble learning, the SSO technique is utilized as a generic ensemble technique where multiple optimized subsets of samples from each class are selected for building an ensemble classifier. We demonstrate the utilities and advantages of the proposed techniques on a variety of bioinformatics applications where class imbalance, small sample size, and noisy data are prevalent.

  12. Influence of rub-in technique on required application time and hand coverage in hygienic hand disinfection.

    Science.gov (United States)

    Kampf, Günter; Reichel, Mirja; Feil, Yvonne; Eggerstedt, Sven; Kaulfers, Paul-Michael

    2008-10-29

    Recent data indicate that full efficacy of a hand rub preparation for hygienic hand disinfection can be achieved within 15 seconds (s). However, the efficacy test used for the European Norm (EN) 1500 samples only the fingertips. Therefore, we investigated hand coverage using sixteen different application variations. The hand rub was supplemented with a fluorescent dye, and hands were assessed under UV light by a blind test, before and after application. Fifteen non-healthcare workers were used as subjects for each application variation apart from one test which was done with a group of twenty healthcare workers. All tests apart from the reference procedure were performed using 3 mL of hand rub. The EN 1500 reference procedure, which consists of 6 specific rub-in steps performed twice with an aliquot of 3 ml each time, served as a control. In one part of this study, each of the six steps was performed from one to five times before proceeding to the next step. In another part of the study, the entire sequence of six steps was performed from one to five times. Finally, all subjects were instructed to cover both hands completely, irrespective of any specific steps ("responsible application"). Each rub-in technique was evaluated for untreated skin areas. The reference procedure lasted on average 75 s and resulted in 53% of subjects with at least one untreated area on the hands. Five repetitions of the rub-in steps lasted on average 37 s with 67% of subjects having incompletely treated hands. One repetition lasted on average 17 s, and all subjects had at least one untreated area. Repeating the sequence of steps lasted longer, but did not yield a better result. "Responsible application" was quite fast, lasting 25 s among non-healthcare worker subjects and 28 s among healthcare workers. It was also effective, with 53% and 55% of hands being incompletely treated. New techniques were as fast and effective as "responsible application". Large untreated areas were found only

  13. Influence of rub-in technique on required application time and hand coverage in hygienic hand disinfection

    Directory of Open Access Journals (Sweden)

    Feil Yvonne

    2008-10-01

    Full Text Available Abstract Background Recent data indicate that full efficacy of a hand rub preparation for hygienic hand disinfection can be achieved within 15 seconds (s. However, the efficacy test used for the European Norm (EN 1500 samples only the fingertips. Therefore, we investigated hand coverage using sixteen different application variations. The hand rub was supplemented with a fluorescent dye, and hands were assessed under UV light by a blind test, before and after application. Fifteen non-healthcare workers were used as subjects for each application variation apart from one test which was done with a group of twenty healthcare workers. All tests apart from the reference procedure were performed using 3 mL of hand rub. The EN 1500 reference procedure, which consists of 6 specific rub-in steps performed twice with an aliquot of 3 ml each time, served as a control. In one part of this study, each of the six steps was performed from one to five times before proceeding to the next step. In another part of the study, the entire sequence of six steps was performed from one to five times. Finally, all subjects were instructed to cover both hands completely, irrespective of any specific steps ("responsible application". Each rub-in technique was evaluated for untreated skin areas. Results The reference procedure lasted on average 75 s and resulted in 53% of subjects with at least one untreated area on the hands. Five repetitions of the rub-in steps lasted on average 37 s with 67% of subjects having incompletely treated hands. One repetition lasted on average 17 s, and all subjects had at least one untreated area. Repeating the sequence of steps lasted longer, but did not yield a better result. "Responsible application" was quite fast, lasting 25 s among non-healthcare worker subjects and 28 s among healthcare workers. It was also effective, with 53% and 55% of hands being incompletely treated. New techniques were as fast and effective as "responsible

  14. Laboratory Determinants of Repeated-Sprint and Sport-Specific-Technique Ability in World-Class Ice Sledge Hockey Players.

    Science.gov (United States)

    Baumgart, Julia Kathrin; Sandbakk, Øyvind

    2016-03-01

    To investigate on-ice repeated-sprint and sports-specific-technique abilities and the relationships to aerobic and anaerobic off-ice capacities in world-class ice sledge hockey players. Twelve Norwegian national team players performed 8 repeated maximal 30-m sprints and a sports-specific-technique test while upper-body poling on ice, followed by 4 maximal upper-body strength tests and 8-s peak power and 3-min peak aerobic-capacity (VO2peak) tests while ergometer poling. The fastest 30-m sprint time was 6.5 ± 0.4 s, the fastest initial 10-m split-time 2.9 ± 0.2 s, and the corresponding power output 212 ± 37 W. Average 30-m time during the 8 repeated sprints was 6.7 ± 0.4 s, and the sprint-time decrement was 4.3% ± 1.8%. Time to execute the sport-specific-technique test was 25.6 ± 2.7 s. Averaged 1-repetition-maximum strength of the 4 exercises correlated with the fastest 30-m sprint time (r = -.77), the fastest initial 10-m split time (r = -.72), the corresponding power output (r = .67), and the average 30-m sprint time (r = -.84) (all P sprint test correlated with the highest initial 10-m power (r = .83, P sprint time (r = -.68, P sprint-time decrement. All off-ice variables except VO2peak correlated with technique-test time (r = -.58 to .73, all P ability to sprint fast and rapid execution of a technically complex test, whereas mode-specific endurance capacity is particularly important for maintenance of sprint ability in ice sledge hockey.

  15. Testing the applicability of six macroscopic skeletal aging techniques on a modern Southeast Asian sample.

    Science.gov (United States)

    Gocha, Timothy P; Ingvoldstad, Megan E; Kolatorowicz, Adam; Cosgriff-Hernandez, Meghan-Tomasita J; Sciulli, Paul W

    2015-04-01

    Most macroscopic skeletal aging techniques used by forensic anthropologists have been developed and tested only on reference material from western populations. This study examined the performance of six aging techniques on a known age sample of 88 Southeast Asian individuals. Methods examined included the Suchey-Brooks method of aging the symphyseal face of the os pubis (Brooks and Suchey, Hum. Evol. 5 (1990) 227), Buckberry and Chamberlain's, Am. J. Phys. Anthropol. 119 (2002) 231 and Osborne et al.'s, J. Forensic Sci. 49 (2004) 1 revisions of the Lovejoy et al., Am. J. Phys. Anthropol. 68 (1985) 15 method of aging the auricular surface of the ilium, İşcan et al.'s, J. Forensic Sci. 29 (1984) 1094, İşcan et al.'s, J. Forensic Sci. 30 (1985) 853 method of aging the sternal end of the fourth rib, and Meindl and Lovejoy's, Am. J. Phys. Anthropol. 68 (1985) 57 methods for aging both lateral-anterior and vault sutures on the cranium. The results of this study indicate that application of aging techniques commonly used in forensic anthropology to individuals identified as Asian, and more specifically Southeast Asian, should not be undertaken injudiciously. Of the six individual methods tested here, the Suchey-Brooks pubic symphysis aging method performs best, though average age estimates were still off by nearly 10 years or greater. Methods for aging the auricular surface perform next best, though the Osborne et al. method works better for individuals below 50 years and the Buckberry and Chamberlain method works better for those above 50 years. Methods for age estimation from the sternal ends of the fourth rib and vault and lateral-anterior cranial sutures perform poorly and are not recommended for use on remains of Southeast Asian ancestry. Combining age estimates from multiple indicators, specifically the pubic symphysis and one auricular surface method, was superior to individual methods. Data and a worked example are provided for calculating the conditional

  16. Efficacy of two sperm preparation techniques in reducing non-specific bacterial species from human semen

    Directory of Open Access Journals (Sweden)

    Prabath K Abeysundara

    2013-01-01

    Full Text Available Context: Artificial reproductive techniques using seminal preparations with bacteria may cause pelvic inflammatory disease and its sequalae. Aims: To assess efficacy of two sperm preparation techniques to clear bacteria and the effect of bacteriospermia on sperm recovery rates. Settings and Design: A descriptive cross-sectional study was carried out among males of subfertile couples. Subjects and Methods: Semen samples were randomly allocated into swim-up method (group S, n = 68 and density gradient method (group D, n = 50 for sperm preparation. Seminal fluid analysis and bacterial cultures were performed in each sample before and after sperm preparation. Statistical Analysis: McNemar′s chi-squared test and independent samples t-test in SPSS version 16.0 were used. Results: Organisms were found in 86 (72.88% out of 118 samples, before sperm preparation; Streptococcus species (n = 40, 46.51% of which 14 were Group D Streptococcus species, Coagulase negative Staphylococcus species (n = 17, 19.76%, Staphylococcus aureus (n = 13, 15.11%, Coliform species (n = 11, 12.79% of which 09 were Escherichia coli and Corynebacterium species (n = 5, 5.81%. There was a statistically significant reduction of culture positive samples in raw vs. processed samples; in group S, 49 (72.05% vs. 16 (23.52% and in group D, 37 (74% vs. 18 (36%. In group S and D, mean (SD recovery rates of culture positive vs. culture negative samples were 39.44% (SD-14.02 vs. 44.22% (SD-22.38, P = 0.39 and 52.50% (SD-37.16 vs. 49.58% (SD-40.32, P = 0.82 respectively. Conclusions: Both sperm preparation methods significantly reduced bacteria in semen, but total clearance was not achieved. Sperm recovery rate was not affected by bacteriospermia.

  17. Innovative directional and position specific sampling technique. Phase 3: Final report, July 1992--September 1994

    Energy Technology Data Exchange (ETDEWEB)

    Hutzel, W.J.; Hill, J.L. III; Foster, E.L.

    1994-09-01

    The POLO System is a major enhancement to the state of the art for subsurface environmental restoration equipment. The system locate s the tip position of penetrometer probes as they are placed underground while meeting the rigid constraints of environmental restoration applications. POLO is applicable to small diameter probes, does not obstruct the center of the probe, is rugged, is unaffected by the presence of steel or other magnetic material, and is capable of remote operation beneath underground tanks or foundations. The development and adaptation of the POLO System for use with penetrometers has progressed through three development phases prior to commercialization. Phases I and II of the contract included the design, testing, and integration of all components of the POLO device. Efforts were made to simulate field conditions in terms of the scale of the components as well as the operating environment. The preestablished success criterion, which has been maintained throughout the research, was to demonstrate path tracking with a total error of less than 0.50% of the distance traveled for distances less than 70 meters. The results tests on individual POLO components showed that the equipment met or exceeded the success criterion. Phase II laboratory scale path tracking experiments also met the success criterion. Phase III moved the POLO System into the field. The full-scale field demonstration tested the ability of the new POLO Module to track the path of a small diameter probe as it moved underground.

  18. Secure Scientific Applications Scheduling Technique for Cloud Computing Environment Using Global League Championship Algorithm

    Science.gov (United States)

    Abdulhamid, Shafi’i Muhammad; Abd Latiff, Muhammad Shafie; Abdul-Salaam, Gaddafi; Hussain Madni, Syed Hamid

    2016-01-01

    Cloud computing system is a huge cluster of interconnected servers residing in a datacenter and dynamically provisioned to clients on-demand via a front-end interface. Scientific applications scheduling in the cloud computing environment is identified as NP-hard problem due to the dynamic nature of heterogeneous resources. Recently, a number of metaheuristics optimization schemes have been applied to address the challenges of applications scheduling in the cloud system, without much emphasis on the issue of secure global scheduling. In this paper, scientific applications scheduling techniques using the Global League Championship Algorithm (GBLCA) optimization technique is first presented for global task scheduling in the cloud environment. The experiment is carried out using CloudSim simulator. The experimental results show that, the proposed GBLCA technique produced remarkable performance improvement rate on the makespan that ranges between 14.44% to 46.41%. It also shows significant reduction in the time taken to securely schedule applications as parametrically measured in terms of the response time. In view of the experimental results, the proposed technique provides better-quality scheduling solution that is suitable for scientific applications task execution in the Cloud Computing environment than the MinMin, MaxMin, Genetic Algorithm (GA) and Ant Colony Optimization (ACO) scheduling techniques. PMID:27384239

  19. Secure Scientific Applications Scheduling Technique for Cloud Computing Environment Using Global League Championship Algorithm.

    Science.gov (United States)

    Abdulhamid, Shafi'i Muhammad; Abd Latiff, Muhammad Shafie; Abdul-Salaam, Gaddafi; Hussain Madni, Syed Hamid

    2016-01-01

    Cloud computing system is a huge cluster of interconnected servers residing in a datacenter and dynamically provisioned to clients on-demand via a front-end interface. Scientific applications scheduling in the cloud computing environment is identified as NP-hard problem due to the dynamic nature of heterogeneous resources. Recently, a number of metaheuristics optimization schemes have been applied to address the challenges of applications scheduling in the cloud system, without much emphasis on the issue of secure global scheduling. In this paper, scientific applications scheduling techniques using the Global League Championship Algorithm (GBLCA) optimization technique is first presented for global task scheduling in the cloud environment. The experiment is carried out using CloudSim simulator. The experimental results show that, the proposed GBLCA technique produced remarkable performance improvement rate on the makespan that ranges between 14.44% to 46.41%. It also shows significant reduction in the time taken to securely schedule applications as parametrically measured in terms of the response time. In view of the experimental results, the proposed technique provides better-quality scheduling solution that is suitable for scientific applications task execution in the Cloud Computing environment than the MinMin, MaxMin, Genetic Algorithm (GA) and Ant Colony Optimization (ACO) scheduling techniques.

  20. 4D Contrast-enhanced MR Angiography with the Keyhole Technique in Children: Technique and Clinical Applications.

    Science.gov (United States)

    Krishnamurthy, Rajesh; Bahouth, Sara M; Muthupillai, Raja

    2016-01-01

    Unlike in adults, contrast agent-enhanced magnetic resonance (MR) angiography in the pediatric population raises unique challenges such as faster heart rates, more rapid arteriovenous transit, smaller structures, smaller volumes of contrast agent used, and more complex disease processes. A need exists for a rapid contrast-enhanced MR angiographic technique that can separate the arterial and venous phases of contrast enhancement in sedated pediatric patients breathing freely during the course of an examination. In time-resolved contrast-enhanced MR angiography with the keyhole method (four-dimensional [4D] contrast-enhanced MR angiography), various spatial and temporal frequency undersampling schemes are used to substantially reduce the time of acquisition without markedly compromising spatial resolution. The keyhole method can be briefly described as an undersampling approach in which only a small region of the k-space (keyhole) around the center is repeatedly sampled while the periphery is sampled only once during acquisition. This method provides a wide range of options that can be used to overcome conventional limitations of contrast-enhanced MR angiography in children and opens the door for several new pediatric applications, including evaluation of congenital heart disease in neonates and infants, thoracic and extremity vascular pathologic conditions, high-flow vascular malformations, systemic vein thrombosis, and pediatric portal hypertension. This review provides a technical overview of 4D contrast-enhanced MR angiography, outlines its advantages and pitfalls in the pediatric population, and also describes various applications in children, including modifications of the technique needed for each application. (©)RSNA, 2016.