WorldWideScience

Sample records for techniques results revealed

  1. Robotic pyeloplasty: technique and results.

    Science.gov (United States)

    Peschel, Reinhard; Neururer, Richard; Bartsch, Georg; Gettman, Matthew T

    2004-11-01

    The da Vinci robotic system can be used to perform dismembered and nondismembered pyeloplasty techniques effectively. Robotics not only seems to improve dexterity and surgical precision but also provides an ergonomic surgical environment for a surgeon performing complex reconstructive procedures such as pyeloplasty. Although performance-enhancing features of the da Vinci robot seem to decrease the difficulty of intracorporeal suturing, a learning curve also exists for telerobotic procedures. This learning curve may decrease as experience with telerobotics increases and as advances in technology are introduced. Presently, the interaction between the primary and assistant surgeon seems crucial to the success of the procedure. Although the early clinical experience with robotic pyeloplasty is favorable, continuing clinical evaluation and careful follow-up are required to determine if the procedure is as efficacious in the long run as open pyeloplasty and laparoscopic pyeloplasty.

  2. Laminotomy in adults: technique and results.

    Science.gov (United States)

    Ruggeri, Andrea; Pichierri, Angelo; Marotta, Nicola; Tarantino, Roberto; Delfini, Roberto

    2012-02-01

    The objective of this study was to describe step by step our surgical technique of laminotomy and analyze our series with regard to spinal deformities (risk and predisposing factors), postoperative pain and rate of postoperative contusions. Data regarding patients who underwent our technique of laminotomy (N = 40, mean follow-up: 52 ms) (N = 40) between 2002 and 2006 were retrospectively evaluated. The technique used is illustrated in depth. Chronic pain was present in 30% with a mean score of 3/10 cm (Graphic Rating Scale). Postoperative kyphoses occurred in three patients, all below 35 years of age and with laminotomies which involved C2 and/or C7. None of these deformities required further surgical treatment because they were self-limiting or asymptomatic at a mean follow-up of 52 months. Based on the results, our technique proved to be safe and effective in terms of late deformities, blood loss, early and chronic postoperative pain and protection from postoperative accidents over the surgical site.

  3. Technique and results of cartilage shield tympanoplasty

    Directory of Open Access Journals (Sweden)

    Sohil I Vadiya

    2014-01-01

    Full Text Available Aim: Use of cartilage for repair of tympanic membrane is recommended by many otologists. The current study aims at evaluating results of cartilage shield tympanoplasty in terms of graft take up and hearing outcomes. Material and Methods: In the current study, cartilage shield tympanoplasty(CST is used in ears with high risk perforations of the tympanic membrane. A total of 40 ears were selected where type I CST was done in 30 ears and type III CST was done in 10 ears. Results: An average of 37.08 dB air bone gap(ABG was present in pre operative time and an average of 19.15 dB of ABG was observed at 6 months after the surgery with hearing gain of 17.28 dB on average was observed. Graft take up rate of 97.5% was observed. The technique is modified to make it easier and to minimize chances of lateralization of graft. Conclusion: The hearing results of this technique are comparable to other methods of tympanic membrane repair.

  4. Amygdalohippocampotomy: surgical technique and clinical results.

    Science.gov (United States)

    Gonçalves-Ferreira, Antonio; Campos, Alexandre Rainha; Herculano-Carvalho, Manuel; Pimentel, Jose; Bentes, Carla; Peralta, Ana Rita; Morgado, Carlos

    2013-05-01

    The removal of mesial temporal structures, namely amygdalohippocampectomy, is the most efficient surgical procedure for the treatment of epilepsy. However, disconnection of the epileptogenic zones, as in temporal lobotomy or, for different purposes, hemispherotomy, have shown equivalent results with less morbidity. Thus, authors of the present study began performing selective amygdalohippocampotomy in cases of refractory mesial temporal lobe epilepsy (TLE) to treat mesial temporal lobe sclerosis (MTLS). The authors conducted a retrospective analysis of all cases of amygdalohippocampotomy collected in a database between November 2007 and March 2011. Since 2007, 21 patients (14 males and 7 females), ages 20-58 years (mean 41 years), all with TLE due to MTLS, were treated with selective ablation of the lateral amygdala plus perihippocampal disconnection (anterior one-half to two-thirds in dominant hemisphere), the left side in 11 cases and the right in 10. In 20 patients the follow-up was 2 or more years (range 24-44 months, average 32 months). Clinical outcome for epilepsy 2 years after surgery (20 patients) was good/very good in 19 patients (95%) with an Engel Class I (15 patients [75%]) or II outcome (4 patients [20%]) and bad in 1 patient (5%) with an Engel Class IV outcome (extratemporal focus and later reoperation). Surgical morbidity included hemiparesis (capsular hypertensive hemorrhage 24 hours after surgery, 1 patient), verbal memory worsening (2 patients), and quadrantanopia (permanent in 2 patients, transient in 1). Late psychiatric depression developed in 3 cases. Operative time was reduced by about 30 minutes (15%) on average with this technique. Amygdalohippocampotomy is as effective as amygdalohippocampectomy to treat MTLS and is a potentially safer, time-saving procedure.

  5. Laparoscopic antireflux surgery--technique and results.

    Science.gov (United States)

    Fingerhut, A; Etienne, J C; Millat, B; Comandella, M G

    1997-09-01

    Although gastroesophageal reflux disease (GERD) can be effectively treated by proton-pump inhibitors, surgery is still the only means of definitive cure of the disease. After introduction of laparoscopic surgery, there has been a clear trend to surgical repair of the incompetent cardia. The indications for surgical treatment are: endoscopically proven esophagitis, persistent or recurrent complaints under medical treatment, esophageal stricture and/or pH-metrically proven acid reflux as well as reflux-induced coughing (chronic aspiration). Although the laparoscopic antireflux operations is a technically demanding procedure, it can be performed with similar results as compared to conventional surgery. The operative technique is reported in detail. From January 1992 to March 1997, 146 consecutive patients with GERD have been operated on laparoscopically. The overall conversion rate was 8.2% (n = 12). 133 patients were operated on according to the Nissen procedure including hiatoplasty. The Toupet operation was performed in only one case. 84 men and 42 women had a mean age of 49 years (20-76). The median duration of symptoms was 48 months (1-600). Except five patients all had medical treatment for at least 2 years. Twice pneumatic balloon dilatation of an esophageal stricture was necessary preoperatively. The median operation time was 210 minutes (70-660). Conversion to open surgery because of intraoperative complications was necessary in 6 patients. Postoperative complications occurred in 14 patients, all of them being successfully treated conservatively. No patient died. 121 patients (90.3%) had follow up examinations for at least 6 months. Retreatment was necessary in 5 cases: 1x slipped Nissen (laparoscopic repair), 1x intrathoracic hernia (conventional reoperation), 2x dysphagia > 4 months postoperatively (endoscopic balloon dilatation) and 1x recurrent ulcer (conventional operation). With a correct indication, laparoscopic Nissen repair for GERD is a suitable

  6. Transjugular liver biopsy: indications, technique and results.

    Science.gov (United States)

    Dohan, A; Guerrache, Y; Boudiaf, M; Gavini, J-P; Kaci, R; Soyer, P

    2014-01-01

    Transjugular liver biopsy is a safe, effective and well-tolerated technique to obtain liver tissue specimens in patients with diffuse liver disease associated with severe coagulopathies or massive ascites. Transjugular liver biopsy is almost always feasible. The use of ultrasonographic guidance for percutaneous puncture of the right internal jugular vein is recommended to decrease the incidence of local cervical minor complications. Semiautomated biopsy devices are very effective in obtaining optimal tissue samples for a precise and definite histological diagnosis with a very low rate of complication. The relative limitations of transjugular liver biopsy are the cost, the radiation dose given to the patient, the increased procedure time by comparison with the more common percutaneous liver biopsy, and the need of a well-trained interventional radiologist.

  7. Imaging Atmospheric Cerenkov Telescopes Techniques and Results

    CERN Document Server

    Bradbury, S M

    2001-01-01

    The hunt for cosmic TeV particle accelerators is prospering through Imaging Atmospheric Cerenkov Telescopes. We face challenges such as low light levels and MHz trigger rates, and the need to distinguish between particle air showers stemming from primary gamma rays and those due to the hadronic cosmic ray background. Our test beam is provided by the Crab Nebula, a steady accelerator of particles to energies beyond 20 TeV. Highly variable gamma-ray emission, coincident with flares at longer wavelengths, is revealing the particle acceleration mechanisms at work in the relativistic jets of Active Galaxies. These 200 GeV to 20 TeV photons propagating over cosmological distances allow us to place a limit on the infra-red background linked to galaxy formation and, some speculate, to the decay of massive relic neutrinos. Gamma rays produced in neutralino annihilation or the evaporation of primordial black holes may also be detectable. These phenomena and a zoo of astrophysical objects will be the targets of the next...

  8. The retreatment: Indications, technique and results

    Energy Technology Data Exchange (ETDEWEB)

    Islak, Civan, E-mail: cislak@istanbul.edu.tr [Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Division of Neuroradiology, Kocamustafapasa, Istanbul 34098 (Turkey)

    2013-10-01

    Durability of endovascular treatment of intracranial aneurysms has always been an issue and a very strong point of criticism. Although studies on long-term results have made it clear that endovascular treatment safe and effective they, nonetheless showed retreatment after endovascular treatment is nearly 5–10 times more frequent than surgical clipping. Risk factors predisposing high probability of retreatment are aneurysm with dissecting nature, incomplete coiling, sac size larger than 10 mm and localization at the bifurcations such as basilar tip. The indications for retreatment after endovascular treatment are not clear yet, although certain morphologic criteria can be used. Retreatment appears not to negate the initial advantage of endovascular treatment over surgical treatment and can be performed very small morbi-mortality numbers.

  9. Mandibular distraction in neonates: indications, technique, results

    Directory of Open Access Journals (Sweden)

    Sesenna Enrico

    2012-02-01

    Full Text Available Abstract Background The Pierre Robin Sequence features were first described by Robin in 1923 and include micrognathia, glossoptosis and respiratory distress with an incidence estimated as 1:8,500 to 1:20,000 newborns. Upper airway obstruction and feeding difficulties are the main concerns related to the pathology. Mandibular distraction should be considered a treatment option (when other treatments result inadequate. Patiants and methods Ten patients between the ages of 1 month and 2 years with severe micrognathia and airway obstruction were treated with Mandibular Distraction Osteogenesis (MDO. All patients underwent fibroscopic examination of the upper airway and a radiographic imaging and/or computed tomography scans to detect malformations and to confirm that the obstruction was caused by posterior tongue displacement. All patients were evaluated by a multidisciplinary team. Indications for surgery included frequent apneic episodes with severe desaturation (70%. Gavage therapy was employed in all patients since oral feeding was not possible. The two tracheotomy patients were 5 months and 2 years old respectively, and the distraction procedure was performed to remove the tracheotomy tube. All patients were treated with bilateral mandibular distraction: two cases with an external multivector distraction device, six cases with an internal non-resorbable device and two cases with an internal resorbable device. In one case, the patient with Goldenhar's Syndrome, the procedure was repeated. Results The resolution of symptoms was obtained in all patients, and, when present, tracheotomy was removed without complications. Of the two patients with pre-existing tracheotomies, in the younger patient (5 months old the tracheotomy was removed 7 days postoperatively. In the Goldenhar's syndrome case (2 years old a Montgomery device was necessary for 6 months due to the presence of tracheotomy-inducted tracheomalacia. Patients were discharged when the

  10. Recurrent coarctation: interventional techniques and results.

    Science.gov (United States)

    Saxena, Anita

    2015-04-01

    Coarctation of the aorta (CoA) accounts for 5% to 8% of all congenital heart defects. With all forms of interventions for native CoA, repeat intervention may be required due to restenosis and/or aneurysm formation. Restenosis rates vary from 5% to 24% and are higher in infants and children and in those with arch hypoplasia. Although repeat surgery can be done for recurrent CoA, guidelines from a number of professional societies have recommended balloon angioplasty with or without stenting as the preferred intervention for patients with isolated recoarctation. For infants and young children with recurrent coarctation, balloon angioplasty has been shown to be safe and effective with low incidence of complications. However, the rates of restenosis and reinterventions are high with balloon angioplasty alone. Endovascular stent placement is indicated, either electively in adults or as a bailout procedure in those who develop a complication such as dissection or intimal tear after balloon angioplasty. Conventionally bare metal stents are used; these can be dilated later if required. Covered stents, introduced more recently, are best reserved for those who have aneurysm at the site of previous repair or who develop a complication such as aortic wall perforation or tear. Stents produce complete abolition of gradients across the coarct segment in a majority of cases with good opening of the lumen on angiography. The long-term results are better than that of balloon angioplasty alone, with very low rates of restenosis. However, endovascular stenting is a technically demanding procedure and can be associated with serious complications rarely.

  11. Revealing components of the galaxy population through nonparametric techniques

    CERN Document Server

    Bamford, Steven P; Nichol, Robert C; Miller, Christopher J; Wasserman, Larry; Genovese, Christopher R; Freeman, Peter E

    2008-01-01

    The distributions of galaxy properties vary with environment, and are often multimodal, suggesting that the galaxy population may be a combination of multiple components. The behaviour of these components versus environment holds details about the processes of galaxy development. To release this information we apply a novel, nonparametric statistical technique, identifying four components present in the distribution of galaxy H$\\alpha$ emission-line equivalent-widths. We interpret these components as passive, star-forming, and two varieties of active galactic nuclei. Independent of this interpretation, the properties of each component are remarkably constant as a function of environment. Only their relative proportions display substantial variation. The galaxy population thus appears to comprise distinct components which are individually independent of environment, with galaxies rapidly transitioning between components as they move into denser environments.

  12. New diagnostic technique for Zeeman-compensated atomic beam slowing: technique and results

    OpenAIRE

    Molenaar, P.A.; Van Der Straten, P.; Heideman, H.G.M.; Metcalf, H

    2001-01-01

    We have developed a new diagnostic tool for the study of Zeeman-compensated slowing of an alkali atomic beam. Our time-of-flight technique measures the longitudinal veloc- ity distribution of the slowed atoms with a resolution below the Doppler limit of 30 cm/s. Furthermore, it can map the position and velocity distribution of atoms in either ground hyperfine level inside the solenoid without any devices inside the solenoid. The technique reveals the optical pumping ef- fects, and shows in de...

  13. Force-clamp analysis techniques reveal stretched exponential unfolding kinetics in ubiquitin

    CERN Document Server

    Lannon, Herbert; Brujic, Jasna

    2012-01-01

    Force-clamp spectroscopy reveals the unfolding and disulfide bond rupture times of single protein molecules as a function of the stretching force, point mutations and solvent conditions. The statistics of these times reveal whether the protein domains are independent of one another, the mechanical hierarchy in the polyprotein chain, and the functional form of the probability distribution from which they originate. It is therefore important to use robust statistical tests to decipher the correct theoretical model underlying the process. Here we develop multiple techniques to compare the well-established experimental data set on ubiquitin with existing theoretical models as a case study. We show that robustness against filtering, agreement with a maximum likelihood function that takes into account experimental artifacts, the Kuiper statistic test and alignment with synthetic data all identify the Weibull or stretched exponential distribution as the best fitting model. Our results are inconsistent with recently ...

  14. Endoscopic thoracic sympathectomy for hyperhidrosis: Technique and results

    Directory of Open Access Journals (Sweden)

    Cina C

    2007-01-01

    Full Text Available Outline: We review the clinical features of hyperhidrosis and the range of treatments used for this condition. We describe in detail the technique of endoscopic sympathectomy. We summarize studies that have reported results of endoscopic sympathectomy. We present new data highlighting the difference in quality of life between patients with hyperhidrosis and controls.

  15. Seismic techniques of enhanced oil recovery: experimental and field results

    Energy Technology Data Exchange (ETDEWEB)

    Kuznetsov, O.L.; Simkin, E.M.; Chilingar, G.V.; Gorfunkel, M.V.; Robertson, J.O. Jr.

    2002-09-15

    Application of secondary and tertiary oil recovery techniques during late field development stages usually yields poor results. The reasons are principally due to the low efficiency of these technologies, probably because the gravity and capillary forces are not properly considered. Improved efficiency for hydrocarbon recovery produced by seismic vibration is discussed. (author)

  16. Endoscopic thoracic sympathectomy for hyperhidrosis: Technique and results

    OpenAIRE

    Cina C; Cina M; Clase C

    2007-01-01

    Outline: We review the clinical features of hyperhidrosis and the range of treatments used for this condition. We describe in detail the technique of endoscopic sympathectomy. We summarize studies that have reported results of endoscopic sympathectomy. We present new data highlighting the difference in quality of life between patients with hyperhidrosis and controls.

  17. Endoscopic thoracic sympathectomy for hyperhidrosis: Technique and results

    Science.gov (United States)

    Cinà, C S; Cinà, M M; Clase, C M

    2007-01-01

    Outline: We review the clinical features of hyperhidrosis and the range of treatments used for this condition. We describe in detail the technique of endoscopic sympathectomy. We summarize studies that have reported results of endoscopic sympathectomy. We present new data highlighting the difference in quality of life between patients with hyperhidrosis and controls. PMID:19789674

  18. The influence of sampling technique on ACT Plus results.

    Science.gov (United States)

    Brouwer, Monique E; Miraziz, Ramen; Agbulos, Grace; Steel, Rona; Hales, Peter; Klineberg, Peter

    2012-12-01

    The manufacturer of the ACT Plus Automated Coagulation Timer, Medtronic Inc., recommends that test cartridges be prewarmed and the activating reagent resuspended (tapped/ mixed) before patient testing. In a busy clinical environment, these recommendations may be overlooked or disregarded. In this study, the impact of sampling technique on ACT Plus test results was investigated. In Series 1, two test cartridges were split into four individual chambers. Two ACT Plus machines were used, allowing for three separate comparisons to be made. The sample results from test Chambers 2 (cold/tapped), 3 (warmed/ not tapped), and 4 (cold/not tapped) were compared individually against the result from test Chamber 1, the recommended technique (warm/tapped). In Series 2, the manufacturer's recommendations were tested using a single double cartridge (warm/ tapped). Results were interpreted using the Bland-Altman method of analysis. The prewarming and tapping of cartridges before use independently influenced the agreement of results when compared with cartridges that were not prewarmed and tapped. Each factor (temperature and mixing) when excluded was found to affect the standard deviation and decrease the agreement of results. By following the manufacturer's recommendations to standardize the sampling technique, ACT Plus test results are more accurate.

  19. Results of NDE Technique Evaluation of Clad Hydrides

    Energy Technology Data Exchange (ETDEWEB)

    Kunerth, Dennis C. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    This report fulfills the M4 milestone, M4FT-14IN0805023, Results of NDE Technique Evaluation of Clad Hydrides, under Work Package Number FT-14IN080502. During service, zirconium alloy fuel cladding will degrade via corrosion/oxidation. Hydrogen, a byproduct of the oxidation process, will be absorbed into the cladding and eventually form hydrides due to low hydrogen solubility limits. The hydride phase is detrimental to the mechanical properties of the cladding and therefore it is important to be able to detect and characterize the presence of this constituent within the cladding. Presently, hydrides are evaluated using destructive examination. If nondestructive evaluation techniques can be used to detect and characterize the hydrides, the potential exists to significantly increase test sample coverage while reducing evaluation time and cost. To demonstrate the viability this approach, an initial evaluation of eddy current and ultrasonic techniques were performed to demonstrate the basic ability to these techniques to detect hydrides or their effects on the microstructure. Conventional continuous wave eddy current techniques were applied to zirconium based cladding test samples thermally processed with hydrogen gas to promote the absorption of hydrogen and subsequent formation of hydrides. The results of the evaluation demonstrate that eddy current inspection approaches have the potential to detect both the physical damage induced by hydrides, e.g. blisters and cracking, as well as the combined effects of absorbed hydrogen and hydride precipitates on the electrical properties of the zirconium alloy. Similarly, measurements of ultrasonic wave velocities indicate changes in the elastic properties resulting from the combined effects of absorbed hydrogen and hydride precipitates as well as changes in geometry in regions of severe degradation. However, for both approaches, the signal responses intended to make the desired measurement incorporate a number of contributing

  20. Intramedullary nailing of the proximal humerus: evolution, technique, and results.

    Science.gov (United States)

    Dilisio, Matthew F; Nowinski, Robert J; Hatzidakis, Armodios M; Fehringer, Edward V

    2016-05-01

    Proximal humerus fractures are the third most common fracture in the elderly. Although most fractures can be treated conservatively with acceptable outcomes, certain fracture patterns are at high risk for progression to humeral malunions, nonunions, stiffness, and post-traumatic arthrosis. The goal of antegrade humeral nailing of proximal humerus fractures is to provide stability to a reduced fracture that allows early motion to optimize patient outcomes. Certain technical pearls are pivotal in managing these difficult fractures with nails; these include rotator cuff management, respect of the soft tissues, anatomic tuberosity position, blood supply maintenance, knowledge of the deforming forces on the proximal humerus, fracture reduction, and rehabilitation strategies. Modern proximal humeral nail designs and techniques assist the surgeon in adhering to these principles and have demonstrated promising outcomes. Humeral nail designs have undergone significant innovation during the past 40 years and now can provide stable fixation in the humeral shaft distally as well as improved stability in the head and tuberosity fragments, which were the common site of fixation failure with earlier generation implants. Compared with other fixation strategies, such as locking plate fixation, no compelling evidence exists to suggest one technique over another. The purpose of this review is to describe the history, results, new designs, and techniques that make modern intramedullary nailing of proximal humerus fractures a viable treatment option.

  1. On-shell Techniques and Universal Results in Quantum Gravity

    CERN Document Server

    Bjerrum-Bohr, N E J; Vanhove, Pierre

    2013-01-01

    We compute the leading post-Newtonian and quantum corrections to the Coulomb and Newtonian potentials using the full modern arsenal of on-shell techniques; we employ spinor-helicity variables everywhere, use the Kawai-Lewellen-Tye (KLT) relations to derive gravity amplitudes from gauge theory and use unitarity methods to extract the terms needed at one-loop order. We stress that our results are universal and thus will hold in any quantum theory of gravity with the same low-energy degrees of freedom as we are considering. Previous results for the corrections to the same potentials, derived historically using Feynman graphs, are verified explicitly, but our approach presents a huge simplification, since starting points for the computations are compact and tedious index contractions and various complicated integral reductions are eliminated from the onset, streamlining the derivations. We also analyze the spin dependence of the results using the KLT factorization, and show how the spinless correction in the fram...

  2. Results of arthrospine assisted percutaneous technique for lumbar discectomy

    Directory of Open Access Journals (Sweden)

    Mohinder Kaushal

    2016-01-01

    Full Text Available Background: Avaialable minimal invasive arthro/endoscopic techniques are not compatible with 30 degree arthroscope which orthopedic surgeons uses in knee and shoulder arthroscopy. Minimally invasive “Arthrospine assisted percutaneous technique for lumbar discectomy” is an attempt to allow standard familiar microsurgical discectomy and decompression to be performed using 30° arthroscope used in knee and shoulder arthroscopy with conventional micro discectomy instruments. Materials and Methods: 150 patients suffering from lumbar disc herniations were operated between January 2004 and December 2012 by indiginously designed Arthrospine system and were evaluated retrospectively. In lumbar discectomy group, there were 85 males and 65 females aged between 18 and 72 years (mean, 38.4 years. The delay between onset of symptoms to surgery was between 3 months to 7 years. Levels operated upon included L1-L2 (n = 3, L2-L3 (n = 2, L3-L4 (n = 8, L4-L5 (n = 90, and L5-S1 (n = 47. Ninety patients had radiculopathy on right side and 60 on left side. There were 22 central, 88 paracentral, 12 contained, 3 extraforaminal, and 25 sequestrated herniations. Standard protocol of preoperative blood tests, x-ray LS Spine and pre operative MRI and pre anaesthetic evaluation for anaesthesia was done in all cases. Technique comprised localization of symptomatic level followed by percutaneous dilatation and insertion of a newly devised arthrospine system devise over a dilator through a 15 mm skin and fascial incision. Arthro/endoscopic discectomy was then carried out by 30° arthroscope and conventional disc surgery instruments. Results: Based on modified Macnab's criteria, of 150 patients operated for lumbar discectomy, 136 (90% patients had excellent to good, 12 (8% had fair, and 2 patients (1.3% had poor results. The complications observed were discitis in 3 patients (2%, dural tear in 4 patients (2.6%, and nerve root injury in 2 patients (1.3%. About 90% patients

  3. Non-invasive techniques for revealing the palette of the Romantic painter Francesco Hayez

    Science.gov (United States)

    Rampazzi, Laura; Brunello, Valentina; Corti, Cristina; Lissoni, Elena

    2017-04-01

    This paper describes the first systematic analysis of the palette of Francesco Hayez, one of the most outstanding artists of European Romanticism, whose painting technique has never been extensively investigated despite the plethora of artistic studies. He lived in a particular moment in the history of painting, as in the first half of the 19th century many synthetic pigments were available, also in tin tubes, but traditional materials were still used. Sixteen paintings on canvas and on panels, created between 1823 and 1868, were analyzed in situ through non-invasive techniques (infrared reflectography and infrared reflection spectroscopy). Imaging investigation provided clues on painting technique, revealing some cases of pentimenti and underdrawings. A preliminary survey was carried out on a hundred pure pigments used up to the 19th century and on new synthetic colours, in order to attain reference spectra for the interpretation of painting spectra. The portable infrared instrument provided insight into Hayez's painting materials, identifying barite, ivory black, lead-tin yellow, Naples yellow, ochres, Prussian blue, and white lead. The pigments were often blended, to obtain a unique fabric appearance or to attain cold shades. The results pointed to a siccative oil as a binder, mixed with white lead so that it could act as a catalyzer in polymerization reactions, and in some cases with a proteinaceous binder and resins. The preparation was made with gypsum and white lead mixed with a siccative oil. The results showed that the artist used a typical traditional palette, throughout his career, in order to lead to brilliant colours and with long-term stability. Anyway, the possible presence of cobalt blue in a few paintings suggests that Hayez had probably started testing the new colours, since the second decade of 19th century.

  4. Non-invasive techniques for revealing the palette of the Romantic painter Francesco Hayez.

    Science.gov (United States)

    Rampazzi, Laura; Brunello, Valentina; Corti, Cristina; Lissoni, Elena

    2017-04-05

    This paper describes the first systematic analysis of the palette of Francesco Hayez, one of the most outstanding artists of European Romanticism, whose painting technique has never been extensively investigated despite the plethora of artistic studies. He lived in a particular moment in the history of painting, as in the first half of the 19th century many synthetic pigments were available, also in tin tubes, but traditional materials were still used. Sixteen paintings on canvas and on panels, created between 1823 and 1868, were analyzed in situ through non-invasive techniques (infrared reflectography and infrared reflection spectroscopy). Imaging investigation provided clues on painting technique, revealing some cases of pentimenti and underdrawings. A preliminary survey was carried out on a hundred pure pigments used up to the 19th century and on new synthetic colours, in order to attain reference spectra for the interpretation of painting spectra. The portable infrared instrument provided insight into Hayez's painting materials, identifying barite, ivory black, lead-tin yellow, Naples yellow, ochres, Prussian blue, and white lead. The pigments were often blended, to obtain a unique fabric appearance or to attain cold shades. The results pointed to a siccative oil as a binder, mixed with white lead so that it could act as a catalyzer in polymerization reactions, and in some cases with a proteinaceous binder and resins. The preparation was made with gypsum and white lead mixed with a siccative oil. The results showed that the artist used a typical traditional palette, throughout his career, in order to lead to brilliant colours and with long-term stability. Anyway, the possible presence of cobalt blue in a few paintings suggests that Hayez had probably started testing the new colours, since the second decade of 19th century. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Hydroponic cultivation techniques: good results with Eg system

    Energy Technology Data Exchange (ETDEWEB)

    Mimiola, G.; Sigliuzzo, C. (Tecnagro, Valenzano (Italy))

    1988-12-01

    This report describes results obtained at the Tecnagro agronomic institute (Valenzano, Italy) in which research is being carried out on the use of the Eg hydroponic system developed in Israel. The research program examined the following: composition of nutritive solutions for ornamental plants and vegetables, methods of application of nutritive substances, breeding densities for ornamental plants and vegetables. Successful nutritive formulas were obtained which resulted, in the case of ornamental plants, in increases in plant height (from 30 to 50%), foliage area (50%), as well as, in shortened growth cycles. For vegetables, shortened growth cycles were developed along with a greater and more consistant production. From the economics point of view, tomatoes proved to be the best choice of vegetable for cultivation with the Eg technique.

  6. Shaeer’s Technique: A Minimally Invasive Procedure for Monsplasty and Revealing the Concealed Penis

    Science.gov (United States)

    2016-01-01

    Background: A concealed penis is a condition where part of the penis is invisible below the surface of the prepubic skin. Dermolipectomy can correct this condition, although it involves a long abdominal crease incision, or infrapubic incision around the base of the penis, and a possibility for genital lymphedema. This study describes Shaeer’s technique, a minimally invasive method for revealing the concealed penis. Methods: A 1- to 2-cm-long incision was cut over the anterior superior iliac spine (ASIS) on either side. A long curved blunt forceps was inserted from one incision, down to the base of the penis and then up to the contralateral ASIS. A 5-mm wide nonabsorbable tape was picked up by the forceps from 1 incision and pulled through to emerge from the other. Pulling on the tape cephalad pulled the mons pubis and revealed the penis. The tape was sutured to the periosteum overlying the ASIS on either side. Patients were followed up for 18 months for penile length, complications, and overall satisfaction. Results: Twenty patients were operated upon. Preoperatively, flaccid visible length was 3 ± 0.9 cm, and erect visible length was 8 ± 4.6 cm. Postoperatively, the flaccid visible length was 7.1 ± 2.1 cm, with a 57.9% improvement in length (P penis. PMID:27622092

  7. Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using "-omics" techniques

    Directory of Open Access Journals (Sweden)

    Workman Chris

    2011-04-01

    Full Text Available Abstract Background Addition of sugar syrups to the basic wort is a popular technique to achieve higher gravity in beer fermentations, but it results in dilution of the free amino nitrogen (FAN content in the medium. The multicomponent protease enzyme Flavourzyme has beneficial effect on the brewer's yeast fermentation performance during high gravity fermentations as it increases the initial FAN value and results in higher FAN uptake, higher specific growth rate, higher ethanol yield and improved flavour profile. Results In the present study, transcriptome and metabolome analysis were used to elucidate the effect on the addition of the multicomponent protease enzyme Flavourzyme and its influence on the metabolism of the brewer's yeast strain Weihenstephan 34/70. The study underlines the importance of sufficient nitrogen availability during the course of beer fermentation. The applied metabolome and transcriptome analysis allowed mapping the effect of the wort sugar composition on the nitrogen uptake. Conclusion Both the transcriptome and the metabolome analysis revealed that there is a significantly higher impact of protease addition for maltose syrup supplemented fermentations, while addition of glucose syrup to increase the gravity in the wort resulted in increased glucose repression that lead to inhibition of amino acid uptake and hereby inhibited the effect of the protease addition.

  8. Computer Package of Metasubject Results Valuation Techniques in Elementary School

    Directory of Open Access Journals (Sweden)

    Ulanovskaya I.M.,

    2014-08-01

    Full Text Available The new Federal state educational standards define requirements for metasubject results of primary schooling. For their assessment, diagnostic package and test methods were developed in Psychological Institute of Russian Academy of Education and Moscow State University of Psychology and Education. A computer version of this package is provided. It includes techniques "Permutations" (author A.Z. Zak, "Calendar" (authors G.A. Zuckerman and O.L. Obukhova, "Quests of Mathematics" (authors S.F. Gorbov, O.V. Savelyeva, N.L. Tabachnikova, "Preparation of the text" (author Z.N. Novlyanskaya. The computer package helps to evaluate main metasubject results related to the development of thinking and mastery of the tools of learning activity. Two additional methods ("Children’s tasks" by G.A. Zuckerman and "Tips" by E.V. Chudinova are focused on the diagnosis of formation of the ability to learn. Using computer tools allow schools to quickly diagnose the results of primary school education, to identify its strengths and weaknesses, prepare correction programs.

  9. Laparoscopic Sacral Uteropexy with Cravat Technique--Experience and Results

    Directory of Open Access Journals (Sweden)

    Murat Api

    2014-08-01

    Full Text Available Objective The aim of the present study was to evaluate the safety and efficacy of a “Cravat’’ technique for the management of uterine prolapse in patients who want to preserve uterus, involving suspension of the uterus from the sacral promontory by using polypropylene mesh. Materials and Methods A prospective observational study between January 2011 and September 2013 was conducted. Prior to surgery, prolapse assessment was undertaken with Baden-Walker halfway system to grade the degree of prolapse at all sites. Patients with severe uterine prolapse (stage II-IV who want to preserve uterus, were operated with Cravat technique. All patients were evaluated at 2 weeks and 6 weeks after surgery and followed for 6 months. Outcomes were evaluated objectively by vaginal examination using Baden-Walker halfway classification, and subjectively classifying patients as ‘very satisfied’, ‘satisfied’ and ‘not satisfied’ at the 6th month postoperatively. Results Sacral uteropexy was successfully performed by laparoscopy in 32/33 patients (one needed to be converted to laparotomy. Nine patients also had a concurrent procedure as colporaphy anterior, colporaphy posterior or transobturator tape. Postoperative recovery has been uneventful with subjective and objective cure rates were 96.9% and 93.9%, respectively at six month. One recurrence of total prolapse needed to be reoperated and two patients with sacrouteropexy still remained at stage 2 prolapse. There have been no cases of graft exposure, rejection or infection with a median follow-up of 23.9 months. Conclusions Laparoscopic sacral uteropexy with “Cravat technique” was found to be safe and simple procedure.

  10. Cystoscopic-assisted partial cystectomy: description of technique and results

    Directory of Open Access Journals (Sweden)

    Gofrit ON

    2014-10-01

    Full Text Available Ofer N Gofrit,1 Amos Shapiro,1 Ran Katz,1 Mordechai Duvdevani,1 Vladimir Yutkin,1 Ezekiel H Landau,1 Kevin C Zorn,2 Guy Hidas,1 Dov Pode1 1Department of Urology, Hadassah Hebrew University Hospital, Jerusalem, Israel; 2Department of Surgery, Section of Urology, Montreal, Canada Background: Partial cystectomy provides oncological results comparable with those of radical cystectomy in selected patients with invasive bladder cancer without the morbidity associated with radical cystectomy and urinary diversion. We describe a novel technique of partial cystectomy that allows accurate identification of tumor margins while minimizing damage to the rest of the bladder. Methods: During the study period, 30 patients underwent partial cystectomy for invasive high-grade cancer. In 19 patients, the traditional method of tumor identification was used, ie, identifying the tumor by palpation and cystotomy. In eleven patients, after mobilization of the bladder, flexible cystoscopy was done and the light of the cystoscope was pointed toward one edge of the planned resected ellipse around the tumor, thus avoiding cystotomy. Results: Patients who underwent partial cystectomy using the novel method were similar in all characteristics to patients operated on using the traditional technique except for tumor diameter which was significantly larger in patients operated on using the novel method (4.3±1.5 cm versus 3.11±1.18 cm, P=0.032. Complications were rare in both types of surgery. The 5-year local recurrence-free survival was marginally superior using the novel method (0.8 versus 0.426, P=0.088. Overall, disease-specific and disease-free survival rates were similar. Conclusion: The use of a flexible cystoscope during partial cystectomy is a simple, low-cost maneuver that assists in planning the bladder incision and minimizes injury to the remaining bladder by avoiding the midline cystotomy. Initial oncological results show a trend toward a lower rate of local

  11. Magnetic resonance imaging urodynamics: technique development and preliminary results

    Directory of Open Access Journals (Sweden)

    Gustavo Borghesi

    2006-06-01

    Full Text Available OBJECTIVES: In this preliminary study we report the development of the video urodynamic technique using magnetic resonance imaging (MRI. MATERIALS AND METHODS: We studied 6 women with genuine stress urinary incontinence, diagnosed by history and physical examination. Urodynamic examination was performed on multichannel equipment with the patient in the supine position. Coughing and Valsalva maneuvers were performed at volumes of 150, 250 and 350 mL. Simultaneously, MRI was carried out by using 1.5 T GE Signa CV/i high-speed scanner with real time fluoroscopic imaging possibilities. Fluoroscopic imaging was accomplished in the corresponding planes with T2-weighted single shot fast spin echo sequences at a speed of about 1 frame per second. Both studies were recorded and synchronized, resulting in a single video urodynamic examination. RESULTS: Dynamic MRI with cine-loop reconstruction of 1 image per second demonstrated the movement of all compartment of the relaxed pelvis during straining with the concomitant registration of abdominal and intravesical pressures. In 5 patients, urinary leakage was demonstrated during straining and the Valsalva leak point pressure (VLPP was determined as the vesical pressure at leak subtracted from baseline bladder pressure. Mean VLPP was 72.6 cm H2O (ranging from 43 to 122 cm H2O. CONCLUSIONS: The concept of MRI video urodynamics is feasible. In a clinical perspective, practical aspects represent a barrier to daily use and it should be recommended for research purposes.

  12. Transcorporeal cervical foraminotomy: description of technique and results

    Directory of Open Access Journals (Sweden)

    Guilherme Pereira Corrêa Meyer

    2014-09-01

    Full Text Available OBJECTIVE: Retrospective analyses of 216 patients undergoing foraminal decompression with transcorporeal approach and review of the surgical technique. METHOD: 216 patients with minimum follow-up of 2 years and an average of 41.8 months were included in the study. The clinical records of these patients were reviewed for complications, NDI (neck disability index and VAS (visual analogue scale. Pre and post-operative radiographs were used to evaluate the disc height. RESULTS: At the end of follow-up patients had significant clinical improvement with reduction of NDI of 88.3% and 86.5% and 68.3% of the VAS for neck and upper limb, respectively (p<0.05. A reduction of 8.8% of the disc height was observed without other complications associated (p<0.05. CONCLUSION: Radicular decompression through a transcorporeal approach is an alternative that provides good clinical results without the need for a fusion and with few complications.

  13. “ROCAMBOLE-LIKE” BICEPS TENODESIS: TECHNIQUE AND RESULTS

    Science.gov (United States)

    Godinho, Glaydson Gomes; Mesquita, Fabrício Augusto Silva; França, Flávio de Oliveira; Freitas, José Márcio Alves

    2015-01-01

    Objective: To present a new technique for bicipital tenodesis and its results: accomplished partially via arthroscopy and grounded in concepts of the normal and pathological anatomy of the tendon of the biceps long head. It is based on the predisposition of this tendon towards becoming attached to the intertubercular sulcus after rupture or tenotomy (auto-tenodesis). Methods: Evaluations were conducted on 63 patients (63 shoulders), aged from 32 to 77 years (average 55), consisting of 32 females (51%) and 31 males (49%). Thirty-five of the patients (55.6%) were over 60 years of age and 28 patients (44.4%) were under 60 years of age. Eighteen were sports participants (28.6%). Fourteen had injuries associated with the subscapularis (22.2%). The average follow up was 43 months (ranging from 12 to 74 months). The right shoulder accounted for 48 cases (76.2%), of which one was a left-handed individual and 47 were right-handed. The left shoulder accounted for 15 (23%) of the patients, of whom two were left-handed and 13 were right-handed. There were no bilateral occurrences. The statistical analysis were done using SPSS version 18. Pearson's chi-square test and continuity corrections were used to investigate the statistical significance of associations between variables. Associations were taken to be statistically significant when p was less than 0.05. Results: Residual Popeye deformity was perceived by seven patients (11.1%); it was only observed by the examiner in 15 cases (23.8%); and neither the patient nor the examiner observed it in 41 cases (65%). There were no statistically valid influences from age, participation in contact or throwing sports, subscapularis tendon-associated injury or Popeye deformity. Fifty-eight patients (92.06%) were satisfied, two patients were dissatisfied (3.17%) and three patients were indifferent (4.76%). Conclusion: The technique presented high patient satisfaction rates (92.06%) and residual deformity was perceived by 11.1% of the

  14. Field results of antifouling techniques for optical instruments

    Science.gov (United States)

    Strahle, W.J.; Hotchkiss, F.S.; Martini, M.A.

    1998-01-01

    An anti-fouling technique is developed for the protection of optical instruments from biofouling which leaches a bromide compound into a sample chamber and pumps new water into the chamber prior to measurement. The primary advantage of using bromide is that it is less toxic than the metal-based antifoulants. The drawback of the bromide technique is also discussed.

  15. The SIGN nail for knee fusion: technique and clinical results

    Directory of Open Access Journals (Sweden)

    Anderson Duane Ray

    2016-01-01

    Full Text Available Purpose: Evaluate the efficacy of using the SIGN nail for instrumented knee fusion. Methods: Six consecutive patients (seven knees, three males with an average age of 30.5 years (range, 18–50 years underwent a knee arthrodesis with SIGN nail (mean follow-up 10.7 months; range, 8–14 months. Diagnoses included tuberculosis (two knees, congenital knee dislocation in two knees (one patient, bacterial septic arthritis (one knee, malunited spontaneous fusion (one knee, and severe gout with 90° flexion contracture (one knee. The nail was inserted through an anteromedial entry point on the femur and full weightbearing was permitted immediately. Results: All knees had clinical and radiographic evidence of fusion at final follow-up and none required further surgery. Four of six patients ambulated without assistive device, and all patients reported improved overall physical function. There were no post-operative complications. Conclusion: The technique described utilizing the SIGN nail is both safe and effective for knee arthrodesis and useful for austere environments with limited fluoroscopy and implant options.

  16. Endoscopic incisional therapy for benign esophageal strictures: Technique and results.

    Science.gov (United States)

    Samanta, Jayanta; Dhaka, Narendra; Sinha, Saroj Kant; Kochhar, Rakesh

    2015-12-25

    Benign esophageal strictures refractory to the conventional balloon or bougie dilatation may be subjected to various adjunctive modes of therapy, one of them being endoscopic incisional therapy (EIT). A proper delineation of the stricture anatomy is a prerequisite. A host of electrocautery and mechanical devices may be used, the most common being the use of needle knife, either standard or insulated tip. The technique entails radial incision and cutting off of the stenotic rim. Adjunctive therapies, to prevent re-stenosis, such as balloon dilatation, oral or intralesional steroids or argon plasma coagulation can be used. The common strictures where EIT has been successfully used are Schatzki's rings (SR) and anastomotic strictures (AS). Short segment strictures (< 1 cm) have been found to have the best outcome. When compared with routine balloon dilatation, EIT has equivalent results in treatment naïve cases but better long term outcome in refractory cases. Anecdotal reports of its use in other types of strictures have been noted. Post procedure complications of EIT are mild and comparable to dilatation therapy. As of the current evidence, incisional therapy can be used for management of refractory AS and SR with relatively short stenosis (< 1 cm) with good safety profile and acceptable long term patency.

  17. Dust tracking techniques applied to the STARDUST facility: First results

    Energy Technology Data Exchange (ETDEWEB)

    Malizia, A., E-mail: malizia@ing.uniroma2.it [Associazione EURATOM-ENEA, Department of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome (Italy); Camplani, M. [Grupo de Tratamiento de Imágenes, E.T.S.I de Telecomunicación, Universidad Politécnica de Madrid (Spain); Gelfusa, M. [Associazione EURATOM-ENEA, Department of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome (Italy); Lupelli, I. [Associazione EURATOM-ENEA, Department of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome (Italy); EURATOM/CCFE Association, Culham Science Centre, Abingdon (United Kingdom); Richetta, M.; Antonelli, L.; Conetta, F.; Scarpellini, D.; Carestia, M.; Peluso, E.; Bellecci, C. [Associazione EURATOM-ENEA, Department of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome (Italy); Salgado, L. [Grupo de Tratamiento de Imágenes, E.T.S.I de Telecomunicación, Universidad Politécnica de Madrid (Spain); Video Processing and Understanding Laboratory, Universidad Autónoma de Madrid (Spain); Gaudio, P. [Associazione EURATOM-ENEA, Department of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome (Italy)

    2014-10-15

    Highlights: •Use of an experimental facility, STARDUST, to analyze the dust resuspension problem inside the tokamak in case of loss of vacuum accident. •PIV technique implementation to track the dust during a LOVA reproduction inside STARDUST. •Data imaging techniques to analyze dust velocity field: first results and data discussion. -- Abstract: An important issue related to future nuclear fusion reactors fueled with deuterium and tritium is the creation of large amounts of dust due to several mechanisms (disruptions, ELMs and VDEs). The dust size expected in nuclear fusion experiments (such as ITER) is in the order of microns (between 0.1 and 1000 μm). Almost the total amount of this dust remains in the vacuum vessel (VV). This radiological dust can re-suspend in case of LOVA (loss of vacuum accident) and these phenomena can cause explosions and serious damages to the health of the operators and to the integrity of the device. The authors have developed a facility, STARDUST, in order to reproduce the thermo fluid-dynamic conditions comparable to those expected inside the VV of the next generation of experiments such as ITER in case of LOVA. The dust used inside the STARDUST facility presents particle sizes and physical characteristics comparable with those that created inside the VV of nuclear fusion experiments. In this facility an experimental campaign has been conducted with the purpose of tracking the dust re-suspended at low pressurization rates (comparable to those expected in case of LOVA in ITER and suggested by the General Safety and Security Report ITER-GSSR) using a fast camera with a frame rate from 1000 to 10,000 images per second. The velocity fields of the mobilized dust are derived from the imaging of a two-dimensional slice of the flow illuminated by optically adapted laser beam. The aim of this work is to demonstrate the possibility of dust tracking by means of image processing with the objective of determining the velocity field values

  18. EM techniques for archaeological laboratory experiments: preliminary results

    Science.gov (United States)

    Capozzoli, Luigi; De Martino, Gregory; Giampaolo, Valeria; Raffaele, Luongo; Perciante, Felice; Rizzo, Enzo

    2015-04-01

    model. The integration of electric and electromagnetic data allowed us to overcome the limits of each technique, especially in terms of resolution and depth, in humid/saturated conditions was investigated and the effectiveness of three-dimensional acquisitions was studied to better explore archeological sites and reduce the uncertainties related on the interpretation of geophysical analysis. The complexity of the relationship between archaeological features in the subsoil and their geophysical response requires efforts in the interpretation of resulting data. Reference Campana S. and Piro, S., (2009): Seeing the unseen - Geophysics and landscape archaeology., CRC Press, London, 2. No. of pages: 376. ISBN: 978-0-415-44721-8. Conyers, L. and Goodman, D., (1997): Ground-Penetrating Radar: An Introduction for Archaeologists. Walnut Creek, Calif.: AltaMira Press. Davis, J.L. and Annan, A.P. (1989): Ground-penetrating radar for high-resolution mapping of soil and rock stratigraphy. Geophysical Prospecting, 37, 531-551.

  19. New results on sporadic ionization observed with the API technique

    Science.gov (United States)

    Bakhmetieva, N. V.; Belikovich, V. V.; Kagan, L. M.

    We present new results of our studies of sporadic E-layers E s by means of the artificial periodic irregularities API technique Artificial periodic irregularities were generated in antinodes of the standing electromagnetic wave formed due to interference of HF radio waves transmitted vertically and reflected from the ionosphere The API are horizontally aligned with a vertical scale of one-half of the wavelength lambda of the transmitted wave for more details on the API method and its applications see Belikovich et al Ionospheric Research by Means of Artificial Periodic Irregularities - Katlenburg-Lindau Germany 2002 Copernicus GmbH ISBN 3-936586-03-9 160 pp Recently we have presented and experimentally realized a method to determine the sporadic E-layer ion composition the molecular masses of the predominant metallic ions and the total ion densities on the basis of the measurements of the amplitude and the decay time of the API signals To study the structure of sporadic ionization layers in the E region as well as a possibility and effectiveness of Es modification by high-power radiowave transmissions we designed and carried out another experiment at the SURA facility 56 1 r N 44 1 r E in August 10-15 2004 The ionosphere modification was done by O-mode waves using two SURA transmitters at the frequency 4 3 MHz with effective radiated power ERP of about 60 MW at the transmitting schedule of the 1-min on 2-min off so-called additional heating The third transmitter was used for API formation and

  20. Microendoscopic lumbar discectomy: Technique and results of 188 cases

    Directory of Open Access Journals (Sweden)

    Arvind G Kulkarni

    2014-01-01

    Full Text Available Background: Discectomy performed open or with an operating microscope remains the standard surgical management. Tubular retractor system is being increasingly used. Potential benefits include less muscle and local damage, better cosmesis, decreased pain and operative time and faster recovery after surgery. We have evaluated the outcome of micro endoscopic discectomy (MED utilizing tubular retractors in terms of safety and efficacy of the technique. Materials and Methods: 188 consecutive patients who underwent surgery for herniated disc using the tubular retractors between April 2007 and April 2012 are reported. All patients had a preoperative MRI (Magnetic Resonance Imaging and were operated by a single surgeon with the METRx system (Medtronic, Sofamor-Danek, Memphis, TN using 18 and 16 mm ports. All patients were mobilized as soon as pain subsided and discharged within 24-48 hours post surgery. The results were evaluated by using VAS (Visual Analog Scale 0-5 for back and leg pain and ODI (Oswestry Disability Index. Patients were followed up at intervals of 1 week, 6 weeks, 3 months, 6 months, 12 months and 2 years. Results: The mean age of patients was 46 years (range 16-78 years and the sex ratio was 1.5 males to 1 female. The mean followup was 22 months (range 8-69 months. The mean VAS scale for leg pain improved from 4.14 to 0.76 ( P < 0.05 and the mean VAS scale for back pain improved from 4.1 to 0.9 ( P < 0.05. The mean ODI changed from 59.5 to 22.6 ( P < 0.05. The mean operative time per level was about 50 minutes (range 20-90 minutes. Dural punctures occurred in 11 (5% cases. Average blood loss was 30 ml (range 10-500 ml. A wrong level was identified and later corrected in a case of revision discectomy. Four patients with residual disc-herniation had revision MED and three patients with recurrent disc herniation later underwent fusion. One patient had wound infection which needed a debridement. Conclusion: MED for herniated discs

  1. Examining the Results of Podcast Relaxation Techniques in Higher Education

    Science.gov (United States)

    Ricks, Jenny; Naquin, Millie; Vest, Amy; Hurtt, Dee; Cole, Diane

    2011-01-01

    College students face many stressors such as academic course work, finances, living away from home, and planning for the future. Knowledge of stress management techniques can assist students in coping with such stressors, especially when disseminated through convenient technologies which are increasingly common in their personal and academic…

  2. Genetic Diversity Caused by Environmental Stress in Natural Populations of Niupidujuan as Revealed by RAPD Technique

    Institute of Scientific and Technical Information of China (English)

    DU Ying-da; XING Ming; YANG Zhi-yong; LIU Yan-fei; CHEN Xia

    2011-01-01

    Multiplex environmental factors are generally expected to have significant effects on genetic diversity of plant populations.In this study,randomly amplified polymorphic DNA(RAPD) technique was used to reveal the genetic diversity in the same species of four populations collected from Niupidujuan(Rhododendron chrysanthum) at different altitudes,an endangered species,endemic to Northeast China.Initially,twenty informative and reproducible primers were chosen for final RAPD analysis.A total of 152 clear bands were obtained,including 143 polymorphic ones.With the help of POPGENE software,the poly rate was calculated to be 94.07% and the evenness of amplified bands for every primer was 6.8.Additionally,the mean observed number of alleles was 1.7265 with an effective number of 1.3608.An examination of the gene indicated a diversity of 0.2162 with an information diversity index of 0.3313.For these data,the clustering blurred analysis was performed with the aid of NTSYS-pc software to define the Nei's gene diversity and the Shannon information diversity index of the four plant populations.The relationships between the genetic diversity indexes on the one hand and the geographic and climatic factors on the other hand were estimated by the Pearson correlation with SPSS 11.0 software.The results of the correlation analysis show that there were significant(P<0.05) or highly significant(P<0.01) correlations between each of the genetic diversity indexes and the different temperature which were mainly caused by the altitude different populations located.These data highlight the importance of native populations in shaping the spatial genetic structure in Niupidujuan.

  3. Percutaneous peritoneovenous shunt positioning: technique and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Orsi, Franco; Grasso, Rosario Francesco; Bonomo, Guido; Marinucci, Irene [Division of Radiology, European Institute of Oncology, Milan (Italy); Monti, Cinzia [Institute of Radiology, University of Milan (Italy); Bellomi, Massimo [Division of Radiology, European Institute of Oncology, Milan (Italy); Institute of Radiology, University of Milan (Italy)

    2002-05-01

    Nine peritoneovenous shunts were positioned by percutaneous technique in seven patients with advanced malignancy causing severe refractory ascites, and in two patients with hepatic cirrhosis (one with hepatocarcinoma). In all patients the shunts were percutaneously placed through the subclavian vein in the angiographic suite under digital fluoroscopic guide. No complications directly related to the procedure occurred. The shunt was successfully positioned in all patients in 60 min average time. No patient showed symptoms related to pulmonary overload or to disseminated intravascular coagulation. All patients had a significant improvement of the objective symptoms related to ascites such as respiratory symptoms, dyspepsia, and functional impairment to evacuation describing an improvement of their quality of life. Maximum shunt patency was 273 days. Percutaneous placement of peritoneovenous shunt is a safe, fast, and inexpensive procedure, extremely useful in resolution of refractory ascites, reducing symptoms, and allowing effective palliation, with a great improvement in quality of life. (orig.)

  4. A Novel Microvascular Flow Technique: Initial Results in Thyroids.

    Science.gov (United States)

    Machado, Priscilla; Segal, Sharon; Lyshchik, Andrej; Forsberg, Flemming

    2016-03-01

    To evaluate the flow imaging capabilities of a new prototype ultrasound (US) image processing technique (superb micro-vascular imaging [SMI]; Toshiba Medical Systems, Tokyo, Japan) for depiction of microvascular flow in normal thyroid tissue and thyroid nodules compared with standard color and power Doppler US imaging.Ten healthy volunteers and 22 patients, with a total of 25 thyroid nodules, scheduled for US-guided fine needle aspiration were enrolled in this prospective study. Subjects underwent US examination consisting of grayscale, color and power Doppler imaging (CDI and PDI) followed by color and monochrome SMI and pulsed Doppler. SMI is a novel, microvascular flow imaging mode implemented on the Aplio 500 US system (Toshiba). SMI uses advanced clutter suppression to extract flow signals from large to small vessels and depicts this information at high frame rates as a color overlay image or as a monochrome map of flow. Two radiologists independently scored still images and digital clips for overall flow detection, vessel branching details and noise on a visual-analog scale of 1 (worst) to 10 (best).For the volunteers SMI visualized microvasculature with significantly lower velocity than CDI and PDI (P SMI demonstrated microvascular flow with significantly higher image scores and provided better depiction of the vessel branching details compared with CDI and PDI (P SMI mode than in the other modes, including color SMI (P SMI mode consistently improved the depiction of thyroid microvascular flow compared with standard CDI and PDI.

  5. Multi-Model Combination techniques for Hydrological Forecasting: Application to Distributed Model Intercomparison Project Results

    Energy Technology Data Exchange (ETDEWEB)

    Ajami, N K; Duan, Q; Gao, X; Sorooshian, S

    2005-04-11

    This paper examines several multi-model combination techniques: the Simple Multi-model Average (SMA), the Multi-Model Super Ensemble (MMSE), Modified Multi-Model Super Ensemble (M3SE) and the Weighted Average Method (WAM). These model combination techniques were evaluated using the results from the Distributed Model Intercomparison Project (DMIP), an international project sponsored by the National Weather Service (NWS) Office of Hydrologic Development (OHD). All of the multi-model combination results were obtained using uncalibrated DMIP model outputs and were compared against the best uncalibrated as well as the best calibrated individual model results. The purpose of this study is to understand how different combination techniques affect the skill levels of the multi-model predictions. This study revealed that the multi-model predictions obtained from uncalibrated single model predictions are generally better than any single member model predictions, even the best calibrated single model predictions. Furthermore, more sophisticated multi-model combination techniques that incorporated bias correction steps work better than simple multi-model average predictions or multi-model predictions without bias correction.

  6. Multi-Model Combination Techniques for Hydrological Forecasting: Application to Distributed Model Intercomparison Project Results

    Energy Technology Data Exchange (ETDEWEB)

    Ajami, N; Duan, Q; Gao, X; Sorooshian, S

    2006-05-08

    This paper examines several multi-model combination techniques: the Simple Multimodel Average (SMA), the Multi-Model Super Ensemble (MMSE), Modified Multi-Model Super Ensemble (M3SE) and the Weighted Average Method (WAM). These model combination techniques were evaluated using the results from the Distributed Model Intercomparison Project (DMIP), an international project sponsored by the National Weather Service (NWS) Office of Hydrologic Development (OHD). All of the multi-model combination results were obtained using uncalibrated DMIP model outputs and were compared against the best uncalibrated as well as the best calibrated individual model results. The purpose of this study is to understand how different combination techniques affect the skill levels of the multi-model predictions. This study revealed that the multi-model predictions obtained from uncalibrated single model predictions are generally better than any single member model predictions, even the best calibrated single model predictions. Furthermore, more sophisticated multi-model combination techniques that incorporated bias correction steps work better than simple multi-model average predictions or multi-model predictions without bias correction.

  7. The GT resonance revealed in beta sup + -decay using new experimental techniques

    CERN Document Server

    Algora, A; Rubio, B; Taín, J L; Agramunt, J; Blomqvist, J M; Batist, L; Borcea, R; Collatz, R; Gadea, A; Gerl, J; Gierlik, M; aGórska, M; Guilbaud, O; Grawe, H; Hellström, M; Hu, Z; Janas, Z; Karny, M; Kirchner, R; Kleinheinz, P; Liu, W; Martínez, T; Moroz, F; Plochocki, A; Rejmund, M; Roeckl, E; Rykaczewski, K; Shibata, M; Szerypo, J; Wittmann, V

    1999-01-01

    The GT beta decay of sup 1 sup 5 sup 0 Ho has been studied with a Total Absorption Spectrometer (TAS), with an array of 6 Euroball CLUSTER Ge detectors (the CLUSTER CUBE), and with an alpha detector. The three techniques complement each other. The results provide the first observation of an extremely sharp resonance in GT beta decay.

  8. New diagnostic technique for Zeeman-compensated atomic beam slowing: technique and results

    NARCIS (Netherlands)

    Molenaar, P.A.; Straten, P. van der; Heideman, H.G.M.; Metcalf, H.

    2001-01-01

    We have developed a new diagnostic tool for the study of Zeeman-compensated slowing of an alkali atomic beam. Our time-of-flight technique measures the longitudinal veloc- ity distribution of the slowed atoms with a resolution below the Doppler limit of 30 cm/s. Furthermore, it can map the position

  9. Double bundle posterior cruciate ligament reconstruction: surgical technique and results.

    Science.gov (United States)

    Fanelli, Gregory C; Beck, John D; Edson, Craig J

    2010-12-01

    The keys to successful posterior cruciate ligament reconstruction are to identify and treat all pathology, use strong graft material, accurately place tunnels in anatomic insertion sites, minimize graft bending, use a mechanical graft tensioning device, use primary and back-up graft fixation, and use the appropriate postoperative rehabilitation program. Adherence to these technical principles results in successful single and double-bundle arthroscopic transtibial tunnel posterior cruciate ligament reconstruction based upon stress radiography, arthrometer, knee ligament rating scales, and patient satisfaction measurements.

  10. Ear surgery techniques results on hearing threshold improvement

    Directory of Open Access Journals (Sweden)

    Farhad Mokhtarinejad

    2013-01-01

    Full Text Available Background: Bone conduction (BC threshold depression is not always by means of sensory neural hearing loss and sometimes it is an artifact caused by middle ear pathologies and ossicular chain problems. In this research, the influences of ear surgeries on bone conduction were evaluated. Materials and Methods: This study was conducted as a clinical trial study. The ear surgery performed on 83 patients classified in four categories: Stapedectomy, tympanomastoid surgery and ossicular reconstruction partially or totally; Partial Ossicular Replacement Prosthesis (PORP and Total Ossicular Replacement Prosthesis (TORP. Bone conduction thresholds assessed in frequencies of 250, 500, 1000, 2000 and 4000 Hz pre and post the surgery. Results: In stapedectomy group, the average of BC threshold in all frequencies improved approximately 6 dB in frequency of 2000 Hz. In tympanomastoid group, BC threshold in the frequency of 500, 1000 and 2000 Hz changed 4 dB (P-value < 0.05. Moreover, In the PORP group, 5 dB enhancement was seen in 1000 and 2000 Hz. In TORP group, the results confirmed that BC threshold improved in all frequencies especially at 4000 Hz about 6.5 dB. Conclusion: In according to results of this study, BC threshold shift was seen after several ear surgeries such as stapedectomy, tympanoplasty, PORP and TORP. The average of BC improvement was approximately 5 dB. It must be considered that BC depression might happen because of ossicular chain problems. Therefore; by resolving middle ear pathologies, the better BC threshold was obtained, the less hearing problems would be faced.

  11. First successful lower-extremity transplantation: technique and functional result.

    Science.gov (United States)

    Zuker, Ronald M; Redett, Rick; Alman, Ben; Coles, John G; Timoney, Norma; Ein, Sigmund H

    2006-05-01

    Composite tissue transplantation has emerged as a viable alternative to prosthetics and complex reconstructive surgery. Thus far it is reserved for cases which cannot be effectively reconstructed and where it offers some benefits over prostheses. It has been used in the upper extremity with encouraging results and, most recently, in the face. This report outlines what is believed to be the first such use in the lower extremity. A normal lower limb in a 3-month-old ischiopagus twin who was not going to survive was transplanted to the appropriate pelvic position, revascularized, and reinnervated in an otherwise healthy sister. The limb survived and, because of the immune compatibility, did not require immune suppressive therapy. The return of muscle function in the transplanted limb is encouraging. The transplanted limb appears to be fully sensate. In addition to reinnervation, the limb is now spontaneously under the cortical control of the recipient.

  12. Measuring 35S of Aerosol Sulfate: Techniques and First Results

    Science.gov (United States)

    Brothers, L. A.; Dominguez, G.; Bluen, B.; Corbin, A.; Abramian, A.; Thiemens, M. H.

    2007-12-01

    On a global and regional level, the cycling of sulfur in the environment has consequences for air quality, human health, and may contribute to global climate change. Due to its multiple oxidation states, the sulfur cycle is very complex and poorly understood. Stable isotopes are currently used to understand reaction pathways as well as sources and sinks of sulfurous compounds in the environment. Sulfur also has one short lived (τ1/2 ~87 d) radioactive isotope (35S) which is continuously made in the atmosphere by the cosmic ray spallation of argon, is then quickly oxidized to 35SO2 and enters the atmospheric sulfur cycle. The short-lived radioactive nature of this isotope of sulfur provides us with potentially powerful tracer for understanding the time scales at which sulfur is oxidized, deposited, and transported in the atmosphere and the deposition of atmospheric sulfate into rivers and water catchments. However, despite its potential, the use of 35S as a tracer of aerosol chemistry has not been fully exploited, Here we present details of instrumental set up for measuring 35S in aerosol sulfate and some preliminary results of measurements of 35S abundances in aerosols from Riverside (inland) and La Jolla (coastal) CA and discuss the sensitivity and limitations of the measurements in providing insights into day/night aerosol chemistry (Riverside) as well as the uptake of SO2 pollution in coastal environments by sea-salt aerosols. Also, we present preliminary results from measurement of sulfate in river water in Ecuador before and after precipitation events.

  13. Randomization techniques for assessing the significance of gene periodicity results

    Directory of Open Access Journals (Sweden)

    Vuokko Niko

    2011-08-01

    Full Text Available Abstract Background Modern high-throughput measurement technologies such as DNA microarrays and next generation sequencers produce extensive datasets. With large datasets the emphasis has been moving from traditional statistical tests to new data mining methods that are capable of detecting complex patterns, such as clusters, regulatory networks, or time series periodicity. Study of periodic gene expression is an interesting research question that also is a good example of challenges involved in the analysis of high-throughput data in general. Unlike for classical statistical tests, the distribution of test statistic for data mining methods cannot be derived analytically. Results We describe the randomization based approach to significance testing, and show how it can be applied to detect periodically expressed genes. We present four randomization methods, three of which have previously been used for gene cycle data. We propose a new method for testing significance of periodicity in gene expression short time series data, such as from gene cycle and circadian clock studies. We argue that the underlying assumptions behind existing significance testing approaches are problematic and some of them unrealistic. We analyze the theoretical properties of the existing and proposed methods, showing how our method can be robustly used to detect genes with exceptionally high periodicity. We also demonstrate the large differences in the number of significant results depending on the chosen randomization methods and parameters of the testing framework. By reanalyzing gene cycle data from various sources, we show how previous estimates on the number of gene cycle controlled genes are not supported by the data. Our randomization approach combined with widely adopted Benjamini-Hochberg multiple testing method yields better predictive power and produces more accurate null distributions than previous methods. Conclusions Existing methods for testing significance

  14. Revealing −1 Programmed Ribosomal Frameshifting Mechanisms by Single-Molecule Techniques and Computational Methods

    Directory of Open Access Journals (Sweden)

    Kai-Chun Chang

    2012-01-01

    Full Text Available Programmed ribosomal frameshifting (PRF serves as an intrinsic translational regulation mechanism employed by some viruses to control the ratio between structural and enzymatic proteins. Most viral mRNAs which use PRF adapt an H-type pseudoknot to stimulate −1 PRF. The relationship between the thermodynamic stability and the frameshifting efficiency of pseudoknots has not been fully understood. Recently, single-molecule force spectroscopy has revealed that the frequency of −1 PRF correlates with the unwinding forces required for disrupting pseudoknots, and that some of the unwinding work dissipates irreversibly due to the torsional restraint of pseudoknots. Complementary to single-molecule techniques, computational modeling provides insights into global motions of the ribosome, whose structural transitions during frameshifting have not yet been elucidated in atomic detail. Taken together, recent advances in biophysical tools may help to develop antiviral therapies that target the ubiquitous −1 PRF mechanism among viruses.

  15. The Results of Teaching Middle School Students Two Relaxation Techniques as Part of a Conflict Prevention Program.

    Science.gov (United States)

    Dacey, John S.; And Others

    1997-01-01

    Boston College Conflict Prevention Program techniques for relaxation and self-control were taught to middle-school students in two Boston schools. Preliminary results from teacher interviews revealed that students spontaneously used these methods to calm their "fight-or-flight" reactions in real conflicts. Results also indicated that…

  16. Revealing t-tubules in striated muscle with new optical super-resolution microscopy techniques

    Directory of Open Access Journals (Sweden)

    Isuru D. Jayasinghe

    2014-12-01

    Full Text Available The t-tubular system plays a central role in the synchronisation of calcium signalling and excitation-contraction coupling in most striated muscle cells. Light microscopy has been used for imaging t-tubules for well over 100 years and together with electron microscopy (EM, has revealed the three-dimensional complexities of the t-system topology within cardiomyocytes and skeletal muscle fibres from a range of species. The emerging super-resolution single molecule localisation microscopy (SMLM techniques are offering a near 10-fold improvement over the resolution of conventional fluorescence light microscopy methods, with the ability to spectrally resolve nanometre scale distributions of multiple molecular targets. In conjunction with the next generation of electron microscopy, SMLM has allowed the visualisation and quantification of intricate t-tubule morphologies within large areas of muscle cells at an unprecedented level of detail. In this paper, we review recent advancements in the t-tubule structural biology with the utility of various microscopy techniques. We outline the technical considerations in adapting SMLM to study t-tubules and its potential to further our understanding of the molecular processes that underlie the sub-micron scale structural alterations observed in a range of muscle pathologies.

  17. Cell-material interactions revealed via material techniques of surface patterning.

    Science.gov (United States)

    Yao, Xiang; Peng, Rong; Ding, Jiandong

    2013-10-04

    Cell-material interactions constitute a key fundamental topic in biomaterials study. Various cell cues and matrix cues as well as soluble factors regulate cell behaviors on materials. These factors are coupled with each other as usual, and thus it is very difficult to unambiguously elucidate the role of each regulator. The recently developed material techniques of surface patterning afford unique ways to reveal the underlying science. This paper reviews the pertinent material techniques to fabricate patterns of microscale and nanoscale resolutions, and corresponding cell studies. Some issues are emphasized, such as cell localization on patterned surfaces of chemical contrast, and effects of cell shape, cell size, cell-cell contact, and seeding density on differentiation of stem cells. Material cues to regulate cell adhesion, cell differentiation and other cell events are further summed up. Effects of some physical properties, such as surface topography and matrix stiffness, on cell behaviors are also discussed; nanoscaled features of substrate surfaces to regulate cell fate are summarized as well. The pertinent work sheds new insight into the cell-material interactions, and is stimulating for biomaterial design in regenerative medicine, tissue engineering, and high-throughput detection, diagnosis, and drug screening. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Murillo's paintings revealed by spectroscopic techniques and dedicated laboratory-made micro X-ray diffraction.

    Science.gov (United States)

    Duran, A; Siguenza, M B; Franquelo, M L; Jimenez de Haro, M C; Justo, A; Perez-Rodriguez, J L

    2010-06-25

    This paper describes one of the first case studies using micro-diffraction laboratory-made systems to analyse painting cross-sections. Pigments, such as lead white, vermilion, red ochre, red lac, lapis lazuli, smalt, lead tin yellow type I, massicot, ivory black, lamp black and malachite, were detected in cross-sections prepared from six Bartolomé Esteban Murillo paintings by micro-Raman and micro-XRD combined with complementary techniques (optical microscopy, SEM-EDS, and FT-IR). The use of micro-XRD was necessary due to the poor results obtained with conventional XRD. In some cases, pigment identification was only possible by combining results from the different analytical techniques utilised in this study.

  19. Predicting Performance of Schools by Applying Data Mining Techniques on Public Examination Results

    Directory of Open Access Journals (Sweden)

    J. Macklin Abraham Navamani

    2015-02-01

    Full Text Available This study work presents a systematic analysis of various features of the higher grade school public examination results data in the state of Tamil Nadu, India through different data mining classification algorithms to predict the performance of Schools. Nowadays the parents always targets to select the right city, school and factors which contributes to the success of the results in schools of their children. There could be possible effects of factors such as Ethnic mix, Medium of study, geography could make a difference in results. The proposed work would focus on two fold factors namely Machine Learning algorithms to predict School performance with satisfying accuracy and to evaluate the data mining technique which would give better accuracy of the learning algorithms. It was found that there exist some apparent and some less noticeable attributes that demonstrate a strong correlation with student performance. Data were collected through the credible source data preparation and correlation analysis. The findings revealed that the public examinations results data was a very helpful predictor of performance of school in order to improve the result with maximum level and also improved the overall accuracy with the help of Adaboost technique.

  20. Application of colour magnification technique for revealing skin microcirculation changes under regional anaesthetic input

    Science.gov (United States)

    Rubins, Uldis; Spigulis, Janis; Miscuks, Aleksejs

    2013-11-01

    In this work the colour magnification technique was applied for monitoring of palm skin microcirculation changes under peripheral (Plexus Brachialis with axiliary access) Regional Anaesthesia (RA). During the RA procedure 20 minute video of patient's forearm was taken at steady light conditions. Video content was processed offline by custom developed Matlab software with build-in colour magnification algorithm that performs temporal filtering of video sequence near-heartbeat frequency, spatial decomposition of video and amplification of pulsatile signal in every pixel of skin image. Using this method, we are able to visualize the subcutaneous microcirculation changes in high spatial resolution. The results showed different blood pulse amplitude dynamics over the skin regions of palm and forearm during the RA. The colour magnification technique could be used for real-time monitoring of RA effect.

  1. Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using "-omics" techniques

    DEFF Research Database (Denmark)

    Piddocke, Maya Petrova; Fazio, Alessandro; Vongsangnak, Wanwipa

    2011-01-01

    Background: Addition of sugar syrups to the basic wort is a popular technique to achieve higher gravity in beer fermentations, but it results in dilution of the free amino nitrogen (FAN) content in the medium. The multicomponent protease enzyme Flavourzyme has beneficial effect on the brewer......'s yeast fermentation performance during high gravity fermentations as it increases the initial FAN value and results in higher FAN uptake, higher specific growth rate, higher ethanol yield and improved flavour profile. Results: In the present study, transcriptome and metabolome analysis were used...... syrup to increase the gravity in the wort resulted in increased glucose repression that lead to inhibition of amino acid uptake and hereby inhibited the effect of the protease addition....

  2. Mechanical properties of ultra thin metallic films revealed by synchrotron techniques

    Energy Technology Data Exchange (ETDEWEB)

    Gruber, Patric Alfons

    2007-07-20

    A prerequisite for the study of the scaling behavior of mechanical properties of ultra thin films is a suitable testing technique. Therefore synchrotron-based in situ testing techniques were developed and optimized in order to characterize the stress evolution in ultra thin metallic films on compliant polymer substrates during isothermal tensile tests. Experimental procedures for polycrystalline as well as single crystalline films were established. These techniques were used to systematically investigate the influence of microstructure, film thickness (20 to 1000 nm) and temperature (-150 to 200 C) on the mechanical properties. Passivated and unpassivated Au and Cu films as well as single crystalline Au films on polyimide substrates were tested. Special care was also dedicated to the microstructural characterization of the samples which was very important for the correct interpretation of the results of the mechanical tests. Down to a film thickness of about 100 to 200 nm the yield strength increased for all film systems (passivated and unpassivated) and microstructures (polycrystalline and singlecrystalline). The influence of different interfaces was smaller than expected. This could be explained by a dislocation source model based on the nucleation of perfect dislocations. For polycrystalline films the film thickness as well as the grain size distribution had to be considered. For smaller film thicknesses the increase in flow stress was weaker and the deformation behavior changed because the nucleation of perfect dislocations became unfavorable. Instead, the film materials used alternative mechanisms to relieve the high stresses. For regular and homogeneous deformation the total strain was accommodated by the nucleation and motion of partial dislocations. If the deformation was localized due to initial cracks in a brittle interlayer or local delamination, dislocation plasticity was not effective enough to relieve the stress concentration and the films showed

  3. Dynamics of human telomerase RNA structure revealed by antisense oligonucleotide technique.

    Science.gov (United States)

    Vasilkova, Daria V; Azhibek, Dulat M; Zatsepin, Timofei S; Naraikina, Yulia V; Prassolov, Vladimir S; Prokofjeva, Maria M; Zvereva, Maria I; Rubtsova, Maria P

    2013-12-01

    Telomeres are the nucleoprotein complexes that cap the linear chromosome ends. Telomerase is a ribonucleoprotein that maintains telomere length in stem, embryonic and cancer cells. Somatic cells don't contain active telomerase and telomere function as mitotic clock and telomere length determines the number of cell divisions. Telomerase RNA (TER) contains the template for telomere synthesis and serves as a structural scaffold for holoenzyme assembly. We compared different oligonucleotide based methods for telomerase RNA inhibition, such as antisense oligonucleotides, knockdown by transient siRNA transfection and silencing by miRNA derived from short expressed RNA hairpin in HEK293 cells. All of these methods were applied to different TER regions. Our results revealed that CR2/CR3 domain of TER is accessible in vitro and in vivo and could serve as an optimal site for oligonucleotide-based telomerase silencing.

  4. Surgery for left ventricular aneurysm after myocardial infarction:techniques selection and results assessment

    Institute of Scientific and Technical Information of China (English)

    CHEN Xin; QIU Zhi-bing; XU Ming; LIU Le-le; JIANG Ying-shuo; WANG Li-ming

    2012-01-01

    Background The most appropriate surgical approach for patients with post-infarction left ventricular (LV) aneurysm remains undetermined.We compared the efficacy of the linear versus patch repair techniques,and investigated the mid-term changes of LV geometry and cardiac function,for repair of LV aneurysms.Methods We reviewed the records of 194 patients who had surgery for a post-infarction LV aneurysm between 1998 and 2010.Short-term and mid-term outcomes,including complications,cardiac function and mortality,were assessed.LV end-diastolic and systolic dimensions (LVEDD and LVESD),LV end-diastolic and end-systolic volume indexes (LVEDVI and LVESVI) and LV ejection fraction (LVEF) were measured on pre-operative and follow-up echocardiography.Results Overall in-hospital mortality was 4.12%,and major morbidity showed no significant differences between the two groups.Multivariate analysis identified preoperative left ventricular end diastolic pressure >20 mmHg,low cardiac output and aortic clamping time >2 hours as risk factors for early mortality.Follow-up revealed that LVEF improved from 37% pre-operation to 45% 12 months post-operation in the patch group (P=0.008),and from 44% pre-operation to 40% 12 months postoperation in the linear group (P=0.032).In contrast,the LVEDVI and LVESVI in the linear group were significantly reduced immediately after the operation,and increased again at follow-up.However,in the patch group,the LVEDVI and LVESVI were significantly reduced at follow-up.And there were significant differences in the correct value changes of LVEF and left ventricular remodeling between linear repair and patch groups.Conclusions Persistent reduction of LV dimensions after the patch repair procedure seems to be a procedure-related problem.The choice of the technique should be tailored on an individual basis and surgeon's preference.The patch remodeling technique results in a better LVEF improvement,further significant reductions in LV dimensions

  5. High throughput techniques to reveal the molecular physiology and evolution of digestion in spiders.

    Science.gov (United States)

    Fuzita, Felipe J; Pinkse, Martijn W H; Patane, José S L; Verhaert, Peter D E M; Lopes, Adriana R

    2016-09-07

    Spiders are known for their predatory efficiency and for their high capacity of digesting relatively large prey. They do this by combining both extracorporeal and intracellular digestion. Whereas many high throughput ("-omics") techniques focus on biomolecules in spider venom, so far this approach has not yet been applied to investigate the protein composition of spider midgut diverticula (MD) and digestive fluid (DF). We here report on our investigations of both MD and DF of the spider Nephilingis (Nephilengys) cruentata through the use of next generation sequencing and shotgun proteomics. This shows that the DF is composed of a variety of hydrolases including peptidases, carbohydrases, lipases and nuclease, as well as of toxins and regulatory proteins. We detect 25 astacins in the DF. Phylogenetic analysis of the corresponding transcript(s) in Arachnida suggests that astacins have acquired an unprecedented role for extracorporeal digestion in Araneae, with different orthologs used by each family. The results of a comparative study of spiders in distinct physiological conditions allow us to propose some digestion mechanisms in this interesting animal taxon. All the high throughput data allowed the demonstration that DF is a secretion originating from the MD. We identified enzymes involved in the extracellular and intracellular phases of digestion. Besides that, data analyses show a large gene duplication event in Araneae digestive process evolution, mainly of astacin genes. We were also able to identify proteins expressed and translated in the digestive system, which until now had been exclusively associated to venom glands.

  6. Genetic diversity in Penaeus chinensis shrimp as revealed by RAPD technique

    Institute of Scientific and Technical Information of China (English)

    庄志猛; 石拓; 孔杰; 刘萍; 刘振辉; 孟宪红; 邓景耀

    2001-01-01

    The random amplified polymorphic DNA analysis was used to estimate genetic diversity in one successively cultivated stock and three wild stocks of Penaeus chinensis shrimp, two of which were collected from the spawning and wintering grounds in the west coast of Korean Peninsula, and one from the feeding ground in the China coast of the Yellow Sea. A random primer kit was employed to scan the genomic DNA in 20 individuals of each index stock. A total of 110 reproducible RAPD markers were obtained, 68.2 % of which showed a sound eonformability within all the individuals detected, implying that the genetic variability in P. chinensis is relatively low. The proportions of polymorphic loci among these four stocks ranged from 20% to 33.3%, while the degrees of genetic polymorphisms varied from 0.0093 to 0.0307. The genetic variability of inter-stocks was higher than that of intra-stock. The genetic diversity in different stocks differed from each other; that is, a less genetic differentiation in the spawning and wintering stocks from the west coast of Korean Peninsula was revealed and their genetic diversities were higher than that of the spawning stock in the Bohai Sea and the China coast of the Yellow Sea. As detected, the genetic diversity in the successively cultivated stock was the lowest among these four stocks. Through genetic distance analysis between a random pair of individuals, a dendrogram of the above-mentioned four stocks was constructed by unweighted pair group method with arithmetic mean. The results based on cluster analysis well fitted with the geographical distribution of P. chinensis in the Bohai and Yellow Seas.

  7. Three-dimensional nipple-areola tattooing: a new technique with superior results.

    Science.gov (United States)

    Halvorson, Eric G; Cormican, Michael; West, Misti E; Myers, Vinnie

    2014-05-01

    Traditional coloring techniques for nipple-areola tattooing ignore the artistic principles of light and shadow to create depth on a two-dimensional surface. The method presented in this article is essentially the inverse of traditional technique and results in a more realistic and three-dimensional reconstruction that can appear better than surgical methods. The application of three-dimensional techniques or "realism" in tattoo artistry has significant potential to improve the aesthetic outcomes of reconstructive surgery.

  8. The strength of EPR and ENDOR techniques in revealing structure-function relationships in metalloproteins.

    Science.gov (United States)

    Van Doorslaer, Sabine; Vinck, Evi

    2007-09-01

    Recent technological and methodological advances have strongly increased the potential of electron paramagnetic resonance (EPR) and electron nuclear double resonance (ENDOR) techniques to characterize the structure and dynamics of metalloproteins. These developments include the introduction of powerful pulsed EPR/ENDOR methodologies and the development of spectrometers operating at very high microwave frequencies and high magnetic fields. This overview focuses on how valuable information about metalloprotein structure-function relations can be obtained using a combination of EPR and ENDOR techniques. After an overview of the historical development and a limited theoretical description of some of the key EPR and ENDOR techniques, their potential will be highlighted using selected examples of applications to iron-, nickel-, cobalt-, and copper-containing proteins. We will end with an outlook of future developments.

  9. Fra Angelico's painting technique revealed by terahertz time-domain imaging (THz-TDI)

    Science.gov (United States)

    Koch Dandolo, Corinna Ludovica; Picollo, Marcello; Cucci, Costanza; Jepsen, Peter Uhd

    2016-10-01

    We have investigated with terahertz time-domain imaging (THz-TDI) the well-known Lamentation over the dead Christ panel painting (San Marco Museum, Florence) painted by Fra Giovanni Angelico within 1436 and 1441. The investigation provided a better understanding of the construction and gilding technique used by the eminent artist, as well as the plastering technique used during the nineteenth-century restoration intervention. The evidence obtained from THz-TDI scans was correlated with the available documentation on the preservation history of the art piece. Erosion and damages documented for the wooden support, especially in the lower margin, found confirmation in the THz-TD images.

  10. Novel and highly diverse fungal endophytes in soybean revealed by the consortium of two different techniques.

    Science.gov (United States)

    de Souza Leite, Tiago; Cnossen-Fassoni, Andréia; Pereira, Olinto Liparini; Mizubuti, Eduardo Seiti Gomide; de Araújo, Elza Fernandes; de Queiroz, Marisa Vieira

    2013-02-01

    Fungal endophytes were isolated from the leaves of soybean cultivars in Brazil using two different isolation techniques - fragment plating and the innovative dilution-to-extinction culturing - to increase the species richness, frequency of isolates and diversity. A total of 241 morphospecies were obtained corresponding to 62 taxa that were identified by analysis of the internal transcribed spacer (ITS) of the ribosomal DNA (rDNA). The Phylum Ascomycota predominated, representing 99% and 95.2% of isolates in the Monsoy and Conquista cultivars, respectively, whereas the Phylum Basidiomycota represented 1% and 4.8% of isolates, respectively. The genera Ampelomyces, Annulohypoxylon, Guignardia, Leptospora, Magnaporthe, Ophiognomonia, Paraconiothyrium, Phaeosphaeriopsis, Rhodotorula, Sporobolomyces, and Xylaria for the first time were isolated from soybean; this suggests that soybean harbours novel and highly diverse fungi. The yeasts genera Rhodotorula and Sporobolomyces (subphylum Pucciniomycotina) represent the Phylum Basidiomycota. The species richness was greater when both isolation techniques were used. The diversity of fungal endophytes was similar in both cultivars when the same isolation technique was used except for Hill's index, N1. The use of ITS region sequences allowed the isolates to be grouped according to Order, Class and Phylum. Ampelomyces, Chaetomium, and Phoma glomerata are endophytic species that may play potential roles in the biological control of soybean pathogens. This study is one of the first to apply extinction-culturing to isolate fungal endophytes in plant leaves, thus contributing to the development and improvement of this technique for future studies.

  11. Comparing visualization techniques for learning second language prosody – first results

    DEFF Research Database (Denmark)

    Niebuhr, Oliver; Alm, Maria Helena; Schümchen, Nathalie

    2017-01-01

    and then analyzed in terms of (a) prosodic-pattern consistency and (b) correctness of the prosodic patterns. In addition, the participants rated the usability of the visualization techniques. The results from the phonological analysis converged with the usability ratings in showing that iconic techniques...

  12. Techniques for Revealing 3d Hidden Archeological Features: Morphological Residual Models as Virtual-Polynomial Texture Maps

    Science.gov (United States)

    Pires, H.; Martínez Rubio, J.; Elorza Arana, A.

    2015-02-01

    The recent developments in 3D scanning technologies are not been accompanied by visualization interfaces. We are still using the same types of visual codes as when maps and drawings were made by hand. The available information in 3D scanning data sets is not being fully exploited by current visualization techniques. In this paper we present recent developments regarding the use of 3D scanning data sets for revealing invisible information from archaeological sites. These sites are affected by a common problem, decay processes, such as erosion, that never ceases its action and endangers the persistence of last vestiges of some peoples and cultures. Rock art engravings, or epigraphical inscriptions, are among the most affected by these processes because they are, due to their one nature, carved at the surface of rocks often exposed to climatic agents. The study and interpretation of these motifs and texts is strongly conditioned by the degree of conservation of the imprints left by our ancestors. Every single detail in the remaining carvings can make a huge difference in the conclusions taken by specialists. We have selected two case-studies severely affected by erosion to present the results of the on-going work dedicated to explore in new ways the information contained in 3D scanning data sets. A new method for depicting subtle morphological features in the surface of objects or sites has been developed. It allows to contrast human patterns still present at the surface but invisible to naked eye or by any other archaeological inspection technique. It was called Morphological Residual Model (MRM) because of its ability to contrast the shallowest morphological details, to which we refer as residuals, contained in the wider forms of the backdrop. Afterwards, we have simulated the process of building Polynomial Texture Maps - a widespread technique that as been contributing to archaeological studies for some years - in a 3D virtual environment using the results of MRM

  13. Innovative combination of spectroscopic techniques to reveal nanoparticle fate in a crop plant

    Science.gov (United States)

    Larue, Camille; Castillo-Michel, Hiram; Stein, Ricardo J.; Fayard, Barbara; Pouyet, Emeline; Villanova, Julie; Magnin, Valérie; Pradas del Real, Ana-Elena; Trcera, Nicolas; Legros, Samuel; Sorieul, Stéphanie; Sarret, Géraldine

    2016-05-01

    Nanotechnology is the new industrial revolution of our century. Its development leads to an increasing use of nanoparticles and thus to their dissemination. Their fate in the environment is of great concern and especially their possible transfer in trophic chains might be an issue for food safety. However, so far our knowledge on this topic has been restricted by the lack of appropriate techniques to characterize their behavior in complex matrices. Here, we present in detail the use of cutting-edge beam-based techniques for nanoparticle in situ localization, quantification and speciation in a crop plant species (Lactuca sativa). Lettuce seedlings have been exposed to TiO2 and Ag nanoparticles and analyzed by inductively coupled plasma spectrometry, micro-particle induced X-ray emission coupled to Rutherford backscattering spectroscopy on nuclear microprobe, micro-X-ray fluorescence spectroscopy and X-ray absorption near edge structure spectroscopy. The benefits and drawbacks of each technique are discussed, and the types of information that can be drawn, for example on the translocation to edible parts, change of speciation within the plant, detoxification mechanisms, or impact on the plant ionome, are highlighted. Such type of coupled approach would be an asset for nanoparticle risk assessment.

  14. A technique for revealing scale-dependent patterns in fracture spacing data

    Science.gov (United States)

    Roy, Ankur; Perfect, Edmund; Dunne, William M.; McKay, Larry D.

    2014-07-01

    Data on fracture spacing along scan lines have been widely analyzed for the purposes of characterization. Most of these studies, however, either consider the cumulative frequency of spacing data without regard to the actual sequence of the spacing values or compute an average spacing that may not work for clustered fractures. The coefficient of variation parameter is often used to differentiate between clustered, random, and anticlustered fractures in a scan line but does not address the issue of scale-dependent variations in spacing. Lacunarity is a parameter that has been previously used for delineating scale-dependent clustering in fracture networks with similar fractal dimensions. This technique has the further capability of identifying scales at which different patterns emerge within the same data set. Lacunarity can also delineate possible fractal behavior. This paper tests the ability of lacunarity to find patterns (fractal/uniform/random) within synthetic and natural fracture clusters. A set of four model scan lines (uniformly spaced fractures, periodically spaced fracture clusters, fractal fracture clusters, and random fractures) was considered. The first derivative of the lacunarity curves of these models was used to find the intercluster distance and organization of fractures within the clusters. The same technique was then applied to a set of two natural fracture scan line data, one with fracture clusters with fractal organization within and the other with randomly spaced fractures. It was found that the proposed technique could discriminate between the random and clustered patterns, find the intercluster distance, and identify the type of spatial organization within the clusters.

  15. In vivo dosimetry for total body irradiation: five-year results and technique comparison.

    Science.gov (United States)

    Patel, Reshma P; Warry, Alison J; Eaton, David J; Collis, Christopher H; Rosenberg, Ivan

    2014-07-08

    The aim of this work is to establish if the new CT-based total body irradiation (TBI) planning techniques used at University College London Hospital (UCLH) and Royal Free Hospital (RFH) are comparable to the previous technique at the Middlesex Hospital (MXH) by analyzing predicted and measured diode results. TBI aims to deliver a homogeneous dose to the entire body, typically using extended SSD fields with beam modulation to limit doses to organs at risk. In vivo dosimetry is used to verify the accuracy of delivered doses. In 2005, when the Middlesex Hospital was decommissioned and merged with UCLH, both UCLH and the RFH introduced updated CT-planned TBI techniques, based on the old MXH technique. More CT slices and in vivo measurement points were used by both; UCLH introduced a beam modulation technique using MLC segments, while RFH updated to a combination of lead compensators and bolus. Semiconductor diodes were used to measure entrance and exit doses in several anatomical locations along the entire body. Diode results from both centers for over five years of treatments were analyzed and compared to the previous MXH technique for accuracy and precision of delivered doses. The most stable location was the field center with standard deviations of 4.1% (MXH), 3.7% (UCLH), and 1.7% (RFH). The least stable position was the ankles. Mean variation with fraction number was within 1.5% for all three techniques. In vivo dosimetry can be used to verify complex modulated CT-planned TBI, and demonstrate improvements and limitations in techniques. The results show that the new UCLH technique is no worse than the previous MXH one and comparable to the current RFH technique.

  16. The Immersive Virtual Reality Experience: A Typology of Users Revealed Through Multiple Correspondence Analysis Combined with Cluster Analysis Technique.

    Science.gov (United States)

    Rosa, Pedro J; Morais, Diogo; Gamito, Pedro; Oliveira, Jorge; Saraiva, Tomaz

    2016-03-01

    Immersive virtual reality is thought to be advantageous by leading to higher levels of presence. However, and despite users getting actively involved in immersive three-dimensional virtual environments that incorporate sound and motion, there are individual factors, such as age, video game knowledge, and the predisposition to immersion, that may be associated with the quality of virtual reality experience. Moreover, one particular concern for users engaged in immersive virtual reality environments (VREs) is the possibility of side effects, such as cybersickness. The literature suggests that at least 60% of virtual reality users report having felt symptoms of cybersickness, which reduces the quality of the virtual reality experience. The aim of this study was thus to profile the right user to be involved in a VRE through head-mounted display. To examine which user characteristics are associated with the most effective virtual reality experience (lower cybersickness), a multiple correspondence analysis combined with cluster analysis technique was performed. Results revealed three distinct profiles, showing that the PC gamer profile is more associated with higher levels of virtual reality effectiveness, that is, higher predisposition to be immersed and reduced cybersickness symptoms in the VRE than console gamer and nongamer. These findings can be a useful orientation in clinical practice and future research as they help identify which users are more predisposed to benefit from immersive VREs.

  17. Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition.

    Science.gov (United States)

    Alhede, Morten; Qvortrup, Klaus; Liebrechts, Ramon; Høiby, Niels; Givskov, Michael; Bjarnsholt, Thomas

    2012-07-01

    Bacterial biofilms are imaged by various kinds of microscopy including confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). One limitation of CLSM is its restricted magnification, which is resolved by the use of SEM that provides high-magnification spatial images of how the single bacteria are located and interact within the biofilm. However, conventional SEM is limited by the requirement of dehydration of the samples during preparation. As biofilms consist mainly of water, the specimen dehydration might alter its morphology. High magnification yet authentic images are important to understand the physiology of biofilms. We compared conventional SEM, Focused Ion Beam (FIB)-SEM and CLSM with SEM techniques [cryo-SEM and environmental-SEM (ESEM)] that do not require dehydration. In the case of cryo-SEM, the biofilm is not dehydrated but kept frozen to obtain high-magnification images closer to the native state of the sample. Using the ESEM technique, no preparation is needed. Applying these methods to biofilms of Pseudomonas aeruginosa showed us that the dehydration of biofilms substantially influences its appearance and that a more authentic biofilm image emerges when combining all methods. © 2012 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  18. Combined Use of Electron and Light Microscopy Techniques Reveals False Secondary Shell Units in Megaloolithidae Eggshells.

    Science.gov (United States)

    Moreno-Azanza, Miguel; Bauluz, Blanca; Canudo, José Ignacio; Gasca, José Manuel; Torcida Fernández-Baldor, Fidel

    2016-01-01

    Abnormalities in the histo- and ultrastructure of the amniote eggshell are often related to diverse factors, such as ambient stress during egg formation, pathologies altering the physiology of the egg-laying females, or evolutionarily selected modifications of the eggshell structure that vary the physical properties of the egg, for example increasing its strength so as to avoid fracture during incubation. When dealing with fossil materials, all the above hypotheses are plausible, but a detailed taphonomical study has to be performed to rule out the possibility that secondary processes of recrystallization have occurred during fossilization. Traditional analyses, such as optical microscopy inspection and cathodoluminescence, have proven not to be enough to understand the taphonomic story of some eggshells. Recently, electron backscatter diffraction has been used, in combination with other techniques, to better understand the alteration of fossil eggshells. Here we present a combined study using scanning electron microscopy, optical microscopy, cathodoluminescence and electron backscatter diffraction of eggshell fragments assigned to Megaloolithus cf. siruguei from the Upper Cretaceous outcrops of the Cameros Basin. We focus our study on the presence of secondary shell units that mimic most aspects of the ultrastructure of the eggshell mammillae, but grow far from the inner surface of the eggshell. We call these structures extra-spherulites, describe their crystal structure and demonstrate their secondary origin. Our study has important implications for the interpretation of secondary shell units as biological or pathological structures. Thus, electron backscatter diffraction complements other microscope techniques as a useful tool for understanding taphonomical alterations in fossil eggshells.

  19. Nerve-sparing techniques and results in robot-assisted radical prostatectomy

    Science.gov (United States)

    Aytac, Omer; Atug, Fatih

    2016-01-01

    Nerve-sparing techniques in robot-assisted radical prostatectomy (RARP) have advanced with the developments defining the prostate anatomy and robotic surgery in recent years. In this review we discussed the surgical anatomy, current nerve-sparing techniques and results of these operations. It is important to define the right and key anatomic landmarks for nerve-sparing in RARP which can demonstrate individual variations. The patients' risk assessment before the operation and intraoperative anatomic variations may affect the nerve-sparing technique, nerve-sparing degree and the approach. There is lack of randomized control trials for different nerve-sparing techniques and approaches in RARP, therefore accurate preoperative and intraoperative assessment of the patient is crucial. Current data shows that, performing the maximum possible nerve-sparing using athermal techniques have better functional outcomes. PMID:27995221

  20. OSCILLATION RESULTS RELATED TO INTEGRAL AVERAGING TECHNIQUE FOR EVEN ORDER NEUTRAL DIFFERENTIAL EQUATION WITH DEVIATING ARGUMENTS

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper, we study an even order neutral differential equation with deviating arguments, and obtain new oscillation results without the assumptions which were required for related results given before. Our results extend and improve many known oscillation criteria, based on the standard integral averaging technique.

  1. Combined techniques for characterising pasta structure reveals how the gluten network slows enzymic digestion rate.

    Science.gov (United States)

    Zou, Wei; Sissons, Mike; Gidley, Michael J; Gilbert, Robert G; Warren, Frederick J

    2015-12-01

    The aim of the present study is to characterise the influence of gluten structure on the kinetics of starch hydrolysis in pasta. Spaghetti and powdered pasta were prepared from three different cultivars of durum semolina, and starch was also purified from each cultivar. Digestion kinetic parameters were obtained through logarithm-of-slope analysis, allowing identification of sequential digestion steps. Purified starch and semolina were digested following a single first-order rate constant, while pasta and powdered pasta followed two sequential first-order rate constants. Rate coefficients were altered by pepsin hydrolysis. Confocal microscopy revealed that, following cooking, starch granules were completely swollen for starch, semolina and pasta powder samples. In pasta, they were completely swollen in the external regions, partially swollen in the intermediate region and almost intact in the pasta strand centre. Gluten entrapment accounts for sequential kinetic steps in starch digestion of pasta; the compact microstructure of pasta also reduces digestion rates.

  2. The phenotypic flexibility of the visceral organs of pythons during digestion revealed by modern imaging techniques

    DEFF Research Database (Denmark)

    Hansen, Kasper; Lauridsen, Henrik; Nielsen, Tobias Wang

    the visceral organs and intestines. Fasting Burmese pythons (Python molurus) were scanned before and at 2, 16, 24, 40, 48, 72 and 132 hours after ingestion of one rat. Acquired images revealed a gradual disappearance of the meal accompanied by an overall expansion of the intestine, shrinking of the gallbladder......, and a 30% increase in heart volume. These immediate responses following ingestion are consistent with previous invasive studies of pythons. In conclusion, our study showed that MRI and CT are capable to repeatedly and non-invasively image the phenotypic flexibility of internal organs in vertebrates.......Pythons, renowned for their abilities to fast for manybmonths and ingest very large meals, exhibit extreme physiological adaptations to their “sit-and-wait predator” lifestyle. In particular, the size and function of their visceral organs are rapidly up- and downregulated during the transitions...

  3. The phenotypic flexibility of the visceral organs of pythons during digestion revealed by modern imaging techniques

    DEFF Research Database (Denmark)

    Hansen, Kasper; Lauridsen, Henrik; Nielsen, Tobias Wang

    Pythons, renowned for their abilities to fast for manybmonths and ingest very large meals, exhibit extreme physiological adaptations to their “sit-and-wait predator” lifestyle. In particular, the size and function of their visceral organs are rapidly up- and downregulated during the transitions...... the visceral organs and intestines. Fasting Burmese pythons (Python molurus) were scanned before and at 2, 16, 24, 40, 48, 72 and 132 hours after ingestion of one rat. Acquired images revealed a gradual disappearance of the meal accompanied by an overall expansion of the intestine, shrinking of the gallbladder......, and a 30% increase in heart volume. These immediate responses following ingestion are consistent with previous invasive studies of pythons. In conclusion, our study showed that MRI and CT are capable to repeatedly and non-invasively image the phenotypic flexibility of internal organs in vertebrates....

  4. Combined Use of Electron and Light Microscopy Techniques Reveals False Secondary Shell Units in Megaloolithidae Eggshells.

    Directory of Open Access Journals (Sweden)

    Miguel Moreno-Azanza

    Full Text Available Abnormalities in the histo- and ultrastructure of the amniote eggshell are often related to diverse factors, such as ambient stress during egg formation, pathologies altering the physiology of the egg-laying females, or evolutionarily selected modifications of the eggshell structure that vary the physical properties of the egg, for example increasing its strength so as to avoid fracture during incubation. When dealing with fossil materials, all the above hypotheses are plausible, but a detailed taphonomical study has to be performed to rule out the possibility that secondary processes of recrystallization have occurred during fossilization. Traditional analyses, such as optical microscopy inspection and cathodoluminescence, have proven not to be enough to understand the taphonomic story of some eggshells. Recently, electron backscatter diffraction has been used, in combination with other techniques, to better understand the alteration of fossil eggshells. Here we present a combined study using scanning electron microscopy, optical microscopy, cathodoluminescence and electron backscatter diffraction of eggshell fragments assigned to Megaloolithus cf. siruguei from the Upper Cretaceous outcrops of the Cameros Basin. We focus our study on the presence of secondary shell units that mimic most aspects of the ultrastructure of the eggshell mammillae, but grow far from the inner surface of the eggshell. We call these structures extra-spherulites, describe their crystal structure and demonstrate their secondary origin. Our study has important implications for the interpretation of secondary shell units as biological or pathological structures. Thus, electron backscatter diffraction complements other microscope techniques as a useful tool for understanding taphonomical alterations in fossil eggshells.

  5. Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiaemolecular form identification

    Directory of Open Access Journals (Sweden)

    Pinto João

    2011-08-01

    Full Text Available Abstract Background Anopheles gambiae M and S molecular forms, the major malaria vectors in the Afro-tropical region, are ongoing a process of ecological diversification and adaptive lineage splitting, which is affecting malaria transmission and vector control strategies in West Africa. These two incipient species are defined on the basis of single nucleotide differences in the IGS and ITS regions of multicopy rDNA located on the X-chromosome. A number of PCR and PCR-RFLP approaches based on form-specific SNPs in the IGS region are used for M and S identification. Moreover, a PCR-method to detect the M-specific insertion of a short interspersed transposable element (SINE200 has recently been introduced as an alternative identification approach. However, a large-scale comparative analysis of four widely used PCR or PCR-RFLP genotyping methods for M and S identification was never carried out to evaluate whether they could be used interchangeably, as commonly assumed. Results The genotyping of more than 400 A. gambiae specimens from nine African countries, and the sequencing of the IGS-amplicon of 115 of them, highlighted discrepancies among results obtained by the different approaches due to different kinds of biases, which may result in an overestimation of MS putative hybrids, as follows: i incorrect match of M and S specific primers used in the allele specific-PCR approach; ii presence of polymorphisms in the recognition sequence of restriction enzymes used in the PCR-RFLP approaches; iii incomplete cleavage during the restriction reactions; iv presence of different copy numbers of M and S-specific IGS-arrays in single individuals in areas of secondary contact between the two forms. Conclusions The results reveal that the PCR and PCR-RFLP approaches most commonly utilized to identify A. gambiae M and S forms are not fully interchangeable as usually assumed, and highlight limits of the actual definition of the two molecular forms, which might

  6. Nerve-sparing techniques and results in robot-assisted radical prostatectomy

    OpenAIRE

    Tavukçu, Hasan Hüseyin; Aytac, Omer; Atug, Fatih

    2016-01-01

    Nerve-sparing techniques in robot-assisted radical prostatectomy (RARP) have advanced with the developments defining the prostate anatomy and robotic surgery in recent years. In this review we discussed the surgical anatomy, current nerve-sparing techniques and results of these operations. It is important to define the right and key anatomic landmarks for nerve-sparing in RARP which can demonstrate individual variations. The patients' risk assessment before the operation and intraoperative an...

  7. Liver metastases: interventional therapeutic techniques and results, state of the art

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, T.J.; Mueller, P.K.; Mack, M.G.; Straub, R.; Engelmann, K. [Dept. of Radiology, Univ. of Frankfurt (Germany); Neuhaus, P. [Dept. of Surgery, Humboldt University of Berlin (Germany)

    1999-05-01

    The liver is the most common site of metastatic tumour deposits. Hepatic metastases are the major cause of morbidity and mortality in patients with gastrointestinal carcinomas and other malignant tumours. The rationale and results for interventional therapeutic techniques in the treatment of liver metastases are presented. For the treatment of patients with irresectable liver metastases, alternative local ablative therapeutic modalities have been developed. Technique and results of local interventional therapies are presented such as microwave-, radiofrequency (RF)- and ultrasound ablation, and laser-induced interstitial therapy (LITT), cryotherapy and local drug administration such as alcohol injection, endotumoral chemotherapy and regional chemoembolisation. In addition to cryotherapy, all ablative techniques can be performed percutaneously with low morbidity and mortality. Cryotherapy is an effective and precise technique for inducing tumour necrosis, but it is currently performed via laparotomy. Percutaneous local alcohol injection results in an inhomogeneous distribution in liver metastases with unreliable control rates. Local chemotherapeutic drug instillation and regional chemoembolisation produces relevant but non-reproducible lesions. Laser-induced interstitial thermotherapy (LITT) performed under MRI guidance results in precise and reproducible areas of induced necrosis with a local control of 94 %, and with an improved survival rate. Interventional therapeutic techniques of liver metastases do result in a remarkable local tumour control rate with improved survival results. (orig.) With 5 figs., 1 tab., 43 refs.

  8. The effect of sampling technique on PCR-based bacteriological results of bovine milk samples.

    Science.gov (United States)

    Hiitiö, Heidi; Simojoki, Heli; Kalmus, Piret; Holopainen, Jani; Pyörälä, Satu; Taponen, Suvi

    2016-08-01

    The aim of the study was to evaluate the effect of sampling technique on the microbiological results of bovine milk samples using multiplex real-time PCR. Comparison was made between a technique where the milk sample was taken directly from the udder cistern of the udder quarter using a needle and vacuum tube and conventional sampling. The effect of different cycle threshold (Ct) cutoff limits on the results was also tested to estimate the amount of amplified DNA in the samples. A total of 113 quarters from 53 cows were tested pairwise using both techniques, and each sample was studied with real-time PCR. Sampling from the udder cistern reduced the number of species per sample compared with conventional sampling. In conventional samples, the number of positive Staphylococcus spp. results was over twice that of samples taken with the needle technique, indicating that most of the Staphylococcus spp. originated from the teat or environmental sources. The Ct values also showed that Staphylococcus spp. were present in most samples only in low numbers. Routine use of multiplex real-time PCR in mastitis diagnostics could benefit from critical evaluation of positive Staphylococcus spp. results with Ct values between 34.0 and 37.0. Our results emphasize the importance of a careful aseptic milk sampling technique and a microbiologically positive result for a milk sample should not be automatically interpreted as an intramammary infection or mastitis. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  9. Barcoded pyrosequencing reveals that consumption of galactooligosaccharides results in a highly specific bifidogenic response in humans.

    Directory of Open Access Journals (Sweden)

    Lauren M G Davis

    Full Text Available Prebiotics are selectively fermented ingredients that allow specific changes in the gastrointestinal microbiota that confer health benefits to the host. However, the effects of prebiotics on the human gut microbiota are incomplete as most studies have relied on methods that fail to cover the breadth of the bacterial community. The goal of this research was to use high throughput multiplex community sequencing of 16S rDNA tags to gain a community wide perspective of the impact of prebiotic galactooligosaccharide (GOS on the fecal microbiota of healthy human subjects. Fecal samples from eighteen healthy adults were previously obtained during a feeding trial in which each subject consumed a GOS-containing product for twelve weeks, with four increasing dosages (0, 2.5, 5, and 10 gram of GOS. Multiplex sequencing of the 16S rDNA tags revealed that GOS induced significant compositional alterations in the fecal microbiota, principally by increasing the abundance of organisms within the Actinobacteria. Specifically, several distinct lineages of Bifidobacterium were enriched. Consumption of GOS led to five- to ten-fold increases in bifidobacteria in half of the subjects. Increases in Firmicutes were also observed, however, these changes were detectable in only a few individuals. The enrichment of bifidobacteria was generally at the expense of one group of bacteria, the Bacteroides. The responses to GOS and the magnitude of the response varied between individuals, were reversible, and were in accordance with dosage. The bifidobacteria were the only bacteria that were consistently and significantly enriched by GOS, although this substrate supported the growth of diverse colonic bacteria in mono-culture experiments. These results suggest that GOS can be used to enrich bifidobacteria in the human gastrointestinal tract with remarkable specificity, and that the bifidogenic properties of GOS that occur in vivo are caused by selective fermentation as well as by

  10. Tympanoplasty: a 5-year review of results using the a la demanda (AAD) technique.

    Science.gov (United States)

    Olaizola, F

    1988-07-01

    The effectiveness of different surgical procedures to eradicate cholesteatoma in the middle ear was studied. The author reviewed 1405 cases conducted during 10 years (1974 to 1984) and found that the most important causes of failure are pocket cholesteatoma and residual cholesteatoma. With the goal of diminishing these factors, a la demanda (AAD) technique has been used for the past 5 years, with optimistic results--only 2.4% failures during this period. Other causes of failures have also been studied. The evolution of the surgical technique has had two orientations: to improve the results and to eliminate the failures. In the author's clinic there has been a percentage of failures, which has motivated an orientation toward more resolutive and destructive instead of conservative, techniques.

  11. Comparison of results from different NDE techniques from ceramic matrix composites with varying porosity levels

    Science.gov (United States)

    Smyth, Imelda; Ojard, Greg; Santhosh, Unni; Ahmad, Jalees; Gowayed, Yasser

    2015-03-01

    Ceramic matrix composites (CMC's) are attractive materials for use in advanced turbine engines. Due to the nature of available processing techniques, however, the amount and distribution of porosity in CMC's can vary greatly. This can be particularly true in parts with complex geometries. It is therefore important to characterize the porosity with non-destructive techniques and understand its effect on properties. A series of CMC samples were fabricated with varying levels of porosity and analyzed with different NDE techniques. The results were categorized and analyzed with respect to ease of interpretation and degree to which they could be quantified and used in models to determine the effects of defects. The results were also correlated with microstructural examination and mechanical properties.

  12. TAPP - Stuttgart technique and result of a large single center series

    Directory of Open Access Journals (Sweden)

    Bittner R

    2006-01-01

    Full Text Available Laparoscopic hernioplasty is assessed as a difficult operation. Operative technique determines the frequency of complications, the time of recovery and the rate of recurrences. A proper technique is absolutely necessary to achieve results that are superior to open hernia surgery. Technique: The key points in our technique are 1 use of nondisposable instruments; 2 use of blunt trocars, consisting of expanding and non-incisive cone-shaped tips; 3 spacious and curved opening to the peritoneum, high above all possible hernia openings; 4 meticulous dissection of the entire pelvic floor; 5 complete reduction of the hernial sac; 6 wide parietalization of the peritoneal sac, at least down to the mid of psoas muscle; 7 implantation of a large mesh, at least 10 cm x 15 cm; 8 fixation of the mesh by clip to Cooper′s ligament, to the rectus muscle and lateral to the epigastric vessels, high above the ileopubic tract; 9 the use of glue allows fixation also to the latero-caudial region; and 10 closure of the peritoneum by running suture. Results: With this technique in 12,678 hernia repairs, the following results could be achieved: operating time - 40 min; morbidity - 2.9%; recurrence rate - 0.7%; disability of work - 14 days. In all types of hernias (recurrence after previous open surgery, recurrence after previous preperitoneal operation, scrotal hernia, hernia in patients after transabdominal prostate resection, similar results could be achieved. Summary: Laparoscopic hernia repair can be performed successfully in clinical practice even by surgeons in training. Precondition for the success is a strictly standardized operative technique and a well-structured educational program.

  13. Long-Term Results of Endoscopic Lumbar Discectomy by "Destandau's Technique"

    Science.gov (United States)

    Kamble, Bhavna; Patond, Kisan

    2016-01-01

    Study Design Prospective study. Purpose The aim of the study was to present long-term results from a 10-year follow-up after endoscopic lumbar discectomy (ELD) by "Destandau's technique". Overview of Literature Endoscopic disc surgery by Destandau's technique using ENDOSPINE Karl Storz system is a relatively new technique. It was introduced in 1993. It has been gaining popularity among the spine surgeons, as it is attractive for small skin incision and allows a gentle and excellent tissue dissection with excellent visualization. Many authors have published results of their own studies; however, in all these studies the long-term follow up of the patients has not been emphasized. Methods A total of 21 patients selected on basis of strict inclusion criteria's underwent ELD from November 2004 to March 2005. Surgery outcome was assessed by using "Prolo's Anatomic-Functional-Economic Rating System" (1986). Patients were followed up to 10 years. In addtion, we compared the results of our study with other studies. Results Outcomes were excellent in 17 patients (80.95%), good in 3 (14.28%) and fair in 1 (4.78%), with no patients having a poor result. In our study, 19 patients (90.47%) were able to resume their previous works/jobs, and only 2 (9.52%) needed to change their jobs for lighter work. No patient retired from his or her previous daily routine following the operation. Conclusions The initial and long-term results are very good for endoscopic lumbar discectomy by Destandau's technique. In properly selected patients it is a safe and minimally invasive technique, and we recommend ELD in properly selected patients. PMID:27114770

  14. Asymmetric distribution of cone-shaped lipids in a highly curved bilayer revealed by a small angle neutron scattering technique

    Energy Technology Data Exchange (ETDEWEB)

    Sakuma, Y; Imai, M [Department of Physics, Ochanomizu University, Bunkyo, Tokyo 112-8610 (Japan); Urakami, N [Department of Physics and Information Sciences, Yamaguchi University, Yamaguchi 753-8512 (Japan); Taniguchi, T, E-mail: imai@phys.ocha.ac.jp [Department of Chemical Engineering, Kyoto University, Kyoto 606-8510 (Japan)

    2011-07-20

    We have investigated the lipid sorting in a binary small unilamellar vesicle (SUV) composed of cone-shaped (1,2-dihexanoyl-sn-glycero-3-phosphocholine: DHPC) and cylinder-shaped (1,2-dipalmitoyl-sn-glycero-3-phosphocholine: DPPC) lipids. In order to reveal the lipid sorting we adopted a contrast matching technique of small angle neutron scattering (SANS), which extracts the distribution of deuterated lipids in the bilayer quantitatively without steric modification of lipids as in fluorescence probe techniques. First the SANS profile of protonated SUVs at a film contrast condition showed that SUVs have a spherical shape with an inner radius of 190 A and a bilayer thickness of 40 A. The SANS profile of deuterated SUVs at a contrast matching condition showed a characteristic scattering profile, indicating an asymmetric distribution of cone-shaped lipids in the bilayer. The characteristic profile was described well by a spherical bilayer model. The fitting revealed that most DHPC molecules are localized in the outer leaflet. Thus the shape of the lipid is strongly coupled with the membrane curvature. We compared the obtained asymmetric distribution of the cone-shaped lipids in the bilayer with the theoretical prediction based on the curvature energy model.

  15. Asymmetric distribution of cone-shaped lipids in a highly curved bilayer revealed by a small angle neutron scattering technique

    Science.gov (United States)

    Sakuma, Y.; Urakami, N.; Taniguchi, T.; Imai, M.

    2011-07-01

    We have investigated the lipid sorting in a binary small unilamellar vesicle (SUV) composed of cone-shaped (1,2-dihexanoyl-sn-glycero-3-phosphocholine: DHPC) and cylinder-shaped (1,2-dipalmitoyl-sn-glycero-3-phosphocholine: DPPC) lipids. In order to reveal the lipid sorting we adopted a contrast matching technique of small angle neutron scattering (SANS), which extracts the distribution of deuterated lipids in the bilayer quantitatively without steric modification of lipids as in fluorescence probe techniques. First the SANS profile of protonated SUVs at a film contrast condition showed that SUVs have a spherical shape with an inner radius of 190 Å and a bilayer thickness of 40 Å. The SANS profile of deuterated SUVs at a contrast matching condition showed a characteristic scattering profile, indicating an asymmetric distribution of cone-shaped lipids in the bilayer. The characteristic profile was described well by a spherical bilayer model. The fitting revealed that most DHPC molecules are localized in the outer leaflet. Thus the shape of the lipid is strongly coupled with the membrane curvature. We compared the obtained asymmetric distribution of the cone-shaped lipids in the bilayer with the theoretical prediction based on the curvature energy model.

  16. Percutaneous radiofrequency ablation of osteoid osteomas. Technique and results; Perkutane Radiofrequenzablation von Osteoidosteomen. Technik und Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Bruners, P.; Penzkofer, T. [Lehrstuhl fuer Angewandte Medizintechnik, Helmholtz Inst. fuer Biomedizinische Technik, RWTH Aachen (Germany); Guenther, R. W.; Mahnken, A. [Klinik fuer Radiologische Diagnostik, Universitaetsklinikum RWTH Aachen (Germany)

    2009-08-15

    Purpose: Osteoid osteoma is a benign primary bone tumor that typically occurs in children and young adults. Besides local pain, which is often worse at night, prompt relief due to medication with acetylsalicylic acid (ASS) is characteristic for this bone lesion. Because long-term medication with ASS does not represent an alternative treatment strategy due to its potentially severe side effects, different minimally invasive image-guided techniques for the therapy of osteoid osteoma have been developed. In this context radiofrequency (RF) ablation in particular has become part of the clinical routine. The technique and results of image-guided RF ablation are compared to alternative treatment strategies. Materials and Methods: Using this technique, an often needle-shaped RF applicator is percutaneously placed into the tumor under image guidance. Then a high-frequency alternating current is applied by the tip of the applicator which leads to ionic motion within the tissue resulting in local heat development and thus in thermal destruction of the surrounding tissue including the tumor. Results: The published primary and secondary success rates of this technique are 87 and 83%, respectively. Surgical resection and open curettage show comparable success rates but are associated with higher complication rates. In addition image-guided RF ablation of osteoid osteomas is associated with low costs. (orig.)

  17. Early and midterm results of kissing stent technique in the management of aortoiliac obstructive disease.

    Science.gov (United States)

    Pulli, Raffaele; Dorigo, Walter; Fargion, Aaron; Angiletta, Domenico; Azas, Leonidas; Pratesi, Giovanni; Alessi Innocenti, Alessandro; Pratesi, Carlo

    2015-04-01

    To retrospectively analyze the early and the midterm results of endovascular management of aortoiliac obstructive disease with the kissing stent technique. From January 2005 to September 2012, 229 consecutive endovascular interventions for aortoiliac obstructive disease were performed; data from all the interventions were prospectively collected in a dedicated database. In 41 patients, the kissing stent technique at the level of aortic bifurcation was performed (group 1), whereas in the remaining 188 it was not (group 2). Perioperative results were compared with chi-squared test. Follow-up results were analyzed with Kaplan-Meier curves and compared with log-rank test. Trans-Atlantic Inter-Society Consensus II C and D lesions were present in 66% of patients in group 1 and in 28.5% in group 2 (P kissing stent technique provided satisfactory results in patients with obstructive aortoiliac diseases, without an increase in immediate and midterm complications, representing an effective solution in complex anatomies. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Geometry of the Farallon Slab Revealed by Joint Interpretation of Wavefield Imaging and Tomography Results from the Earthscope Transportable Array

    Science.gov (United States)

    Pavlis, G. L.; Wang, Y.

    2015-12-01

    A significant number of P and S wave tomography models have been produced in the past decade using various subsets of data from the Earthscope USArray and different inversion algorithms. We focus here on published tomography results that span large portions of the final footprint of the USArray. We use 3D visualization techniques to search for common features in different tomography models. We also compare tomography results to features seen in our current generation wavefield images. Recent innovations of our plane wave migration method have yielded what is arguably the highest resolution image ever produced of the mantle in the vicinity of the transition zone. The new results reveal a rich collection of coherent, dipping structures seen throughout the upper mantle and transition zone. These dipping interfaces are judged significant according to a coherence metric. We treat these surfaces as strain markers to assess proposed models for geometry of the 3D geometry of the Farallon Slab under North America. We find the following geologic interpretations are well supported by independent results: 1. The old Farallon under eastern North America and below the base of transition zone is universally seen as a high velocity anomaly. 2. All results support a simple, 3D kinematic model of the updip limit of the Farallon slab window that follows a track from Cape Mendocino, across Nevada, and northern Arizona and New Mexico. 3. All models show a strong low-velocity mantle under the southwestern U.S. 4. A low-velocity features is universally seen related to the Yellowstone-Snake River system. Shorter wavelength features observed in different tomography models are inconsistent showing that the theme of this session is very important to understand what features are in current results are real. Isopach maps of the thickness of the transition show a systematic difference in transition zone thickness in the western and eastern US. The transition zone thickens in the eastern US in

  19. Rotational Acceleration during Head Impact Resulting from Different Judo Throwing Techniques

    Science.gov (United States)

    MURAYAMA, Haruo; HITOSUGI, Masahito; MOTOZAWA, Yasuki; OGINO, Masahiro; KOYAMA, Katsuhiro

    2014-01-01

    Most severe head injuries in judo are reported as acute subdural hematoma. It is thus necessary to examine the rotational acceleration of the head to clarify the mechanism of head injuries. We determined the rotational acceleration of the head when the subject is thrown by judo techniques. One Japanese male judo expert threw an anthropomorphic test device using two throwing techniques, Osoto-gari and Ouchigari. Rotational and translational head accelerations were measured with and without an under-mat. For Osoto-gari, peak resultant rotational acceleration ranged from 4,284.2 rad/s2 to 5,525.9 rad/s2 and peak resultant translational acceleration ranged from 64.3 g to 87.2 g; for Ouchi-gari, the accelerations respectively ranged from 1,708.0 rad/s2 to 2,104.1 rad/s2 and from 120.2 g to 149.4 g. The resultant rotational acceleration did not decrease with installation of an under-mat for both Ouchi-gari and Osoto-gari. We found that head contact with the tatami could result in the peak values of translational and rotational accelerations, respectively. In general, because kinematics of the body strongly affects translational and rotational accelerations of the head, both accelerations should be measured to analyze the underlying mechanism of head injury. As a primary preventative measure, throwing techniques should be restricted to participants demonstrating ability in ukemi techniques to avoid head contact with the tatami. PMID:24477065

  20. Features of Intangible Assets Inventory Technique and the Recognition of Its Results

    OpenAIRE

    Nataliya Kantsedal

    2014-01-01

    Practical implementation of science-based inventory methodology promotes objective and reliable estimates of results for further interpretation in the accounting system, as well the decision-making on eliminated shortcomings and violations. The scope of the article is an analysis of the legal provisions of inventory of intangible assets and organizing the views of the individual authors to identify problem issues to be addressed in terms of specification of technique for intangible assets inv...

  1. Functional results after cholesteatoma surgery in an adult population using the retrograde mastoidectomy technique.

    Science.gov (United States)

    Minovi, Amir; Venjacob, Johanna; Volkenstein, Stefan; Dornhoffer, John; Dazert, Stefan

    2014-03-01

    In this retrospective study, we analyzed the functional results after using the retrograde mastoidectomy technique for cholesteatoma removal in an adult patient population. The described technique was used at a tertiary referral center for cholesteatoma removal in 218 adult patients, representing 242 operated ears, with an average follow-up time of 20.3 months. With the retrograde mastoidectomy technique, the cholesteatoma is removed posteriorly through the canal wall, from the epitympanic region toward the mastoid, with the option to reconstruct the posterior bony canal wall or create an open mastoid cavity, depending on the size of the defect. Primary surgery was carried out in 58.7 % ears, with the remaining 41.3 % representing revision surgery. In 151 cases, the posterior canal wall was reconstructed, and in 91 cases a classical CWD with an open mastoid cavity was created. In the majority of the cases (n = 213, 88.0 %), a primary hearing restoration was performed. There were 18 recurrences (12.7 %) in primary cases and 22 recurrences (22 %) in revision surgeries. Ninety percent of the recurrences (36 of 40 cases) occurred within 5 years. A postoperative air-bone gap of less than 20 dB was achieved in 61.6 % of the operated ears. Ears with a reconstructed posterior canal wall had significantly better hearing results than those cases in which a CWD procedure was used (air-bone gap of 17.6 versus 22.5 dB, p < 0.05). The retrograde mastoidectomy technique for cholesteatoma removal resulted in satisfying hearing results in the majority of the cases, with a recurrence rate comparable to the current literature.

  2. Evaluation of the functional results after rotator cuff arthroscopic repair with the suture bridge technique

    Directory of Open Access Journals (Sweden)

    Alberto Naoki Miyazaki

    Full Text Available ABSTRACT OBJECTIVE: To evaluate the results of arthroscopic treatment of large and extensive rotator cuff injuries (RCI that involved the supra and infraspinatus muscles using the suture bridge (SB technique. METHODS: Between July 2010 and November 2014, 37 patients with RCI who were treated with SB technique were evaluated. The study included all patients with a minimum follow-up of 12 months who underwent primary surgery of the shoulder. Twenty-four patients were male and 13 were female. The mean age was 60 years (45-75. The dominant side was affected in 32 cases. The most common cause of injury was trauma (18 cases. The mean preoperative motion was 123°, 58°, T11. Through magnetic resonance imaging, 36 fatty degenerations were classified according to Goutallier. Patients underwent rotator cuff repair with SB technique, which consists of using a medial row anchor with two Corkscrew(r fibertape(r or fiberwire(r at the articular margin, associated with lateral fixation without stitch using PushLocks(r or SwiveLocks(r. RESULTS: The mean age was 60 years and mean fatty degeneration was 2.6. The mean range of motion (following the AAOS in the postoperative evaluation was 148° of forward elevation, 55° in lateral rotation and medial rotation in T9. Using the criteria of the University of California at Los Angeles (UCLA, 35 (94% patients had excellent and good results; one (2.7%, fair; and one (2.7%, poor. CONCLUSION: Arthroscopic repair of a large and extensive RCI using SB technique had good and excellent results in 94% of the patients.

  3. Features of Intangible Assets Inventory Technique and the Recognition of Its Results

    OpenAIRE

    Nataliya Kantsedal

    2014-01-01

    Practical implementation of science-based inventory methodology promotes objective and reliable estimates of results for further interpretation in the accounting system, as well the decision-making on eliminated shortcomings and violations. The scope of the article is an analysis of the legal provisions of inventory of intangible assets and organizing the views of the individual authors to identify problem issues to be addressed in terms of specification of technique for intangible assets inv...

  4. Arthroscopic Repair of Combined Bankart and SLAP Lesions: Operative Techniques and Clinical Results

    OpenAIRE

    Cho, Hyung Lae; Lee, Choon Key; Hwang, Tae Hyok; Suh, Kuen Tak; Park, Jong Won

    2010-01-01

    Background To evaluate the clinical results and operation technique of arthroscopic repair of combined Bankart and superior labrum anterior to posterior (SLAP) lesions, all of which had an anterior-inferior Bankart lesion that continued superiorly to include separation of the biceps anchor in the patients presenting recurrent shoulder dislocations. Methods From May 2003 to January 2006, we reviewed 15 cases with combined Bankart and SLAP lesions among 62 patients with recurrent shoulder dislo...

  5. Functional results in airflow improvement using a "flip-flap" alar technique: our experience.

    Science.gov (United States)

    Di Stadio, Arianna; Macro, Carlo

    2017-02-21

    Pinched nasal point can be arising as congenital malformation or as results of unsuccessfully surgery. The nasal valve alteration due to this problem is not only an esthetic problem but also a functional one because can modify the nasal airflow. Several surgical techniques were proposed in literature, we proposed our. The purpose of the study is the evaluation of nose airway flow using our flip-flap technique for correction of pinched nasal tip. This is a retrospective study conducted on twelve patients. Tip cartilages were remodeled by means of autologous alar cartilage grafting. The patients underwent a rhinomanometry pre and post-surgery to evaluate the results, and they performed a self-survey to evaluate their degree of satisfaction in term of airflow sensation improvement. Rhinomanometry showed improved nasal air flow (range from 25% to 75%) in all patients. No significant differences were showed between unilateral and bilateral alar malformation (p=0.49). Patient's satisfaction reached the 87.5%. Our analysis on the combined results (rhinomanometry and surveys) showed that this technique leads to improvement of nasal flow in patients affected by pinched nasal tip in all cases. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  6. Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge

    Science.gov (United States)

    Cash, David M.; Frost, Chris; Iheme, Leonardo O.; Ünay, Devrim; Kandemir, Melek; Fripp, Jurgen; Salvado, Olivier; Bourgeat, Pierrick; Reuter, Martin; Fischl, Bruce; Lorenzi, Marco; Frisoni, Giovanni B.; Pennec, Xavier; Pierson, Ronald K.; Gunter, Jeffrey L.; Senjem, Matthew L.; Jack, Clifford R.; Guizard, Nicolas; Fonov, Vladimir S.; Collins, D. Louis; Modat, Marc; Cardoso, M. Jorge; Leung, Kelvin K.; Wang, Hongzhi; Das, Sandhitsu R.; Yushkevich, Paul A.; Malone, Ian B.; Fox, Nick C.; Schott, Jonathan M.; Ourselin, Sebastien

    2015-01-01

    Structural MRI is widely used for investigating brain atrophy in many neurodegenerative disorders, with several research groups developing and publishing techniques to provide quantitative assessments of this longitudinal change. Often techniques are compared through computation of required sample size estimates for future clinical trials. However interpretation of such comparisons is rendered complex because, despite using the same publicly available cohorts, the various techniques have been assessed with different data exclusions and different statistical analysis models. We created the MIRIAD atrophy challenge in order to test various capabilities of atrophy measurement techniques. The data consisted of 69 subjects (46 Alzheimer's disease, 23 control) who were scanned multiple (up to twelve) times at nine visits over a follow-up period of one to two years, resulting in 708 total image sets. Nine participating groups from 6 countries completed the challenge by providing volumetric measurements of key structures (whole brain, lateral ventricle, left and right hippocampi) for each dataset and atrophy measurements of these structures for each time point pair (both forward and backward) of a given subject. From these results, we formally compared techniques using exactly the same dataset. First, we assessed the repeatability of each technique using rates obtained from short intervals where no measurable atrophy is expected. For those measures that provided direct measures of atrophy between pairs of images, we also assessed symmetry and transitivity. Then, we performed a statistical analysis in a consistent manner using linear mixed effect models. The models, one for repeated measures of volume made at multiple time-points and a second for repeated “direct” measures of change in brain volume, appropriately allowed for the correlation between measures made on the same subject and were shown to fit the data well. From these models, we obtained estimates of the

  7. Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge.

    Science.gov (United States)

    Cash, David M; Frost, Chris; Iheme, Leonardo O; Ünay, Devrim; Kandemir, Melek; Fripp, Jurgen; Salvado, Olivier; Bourgeat, Pierrick; Reuter, Martin; Fischl, Bruce; Lorenzi, Marco; Frisoni, Giovanni B; Pennec, Xavier; Pierson, Ronald K; Gunter, Jeffrey L; Senjem, Matthew L; Jack, Clifford R; Guizard, Nicolas; Fonov, Vladimir S; Collins, D Louis; Modat, Marc; Cardoso, M Jorge; Leung, Kelvin K; Wang, Hongzhi; Das, Sandhitsu R; Yushkevich, Paul A; Malone, Ian B; Fox, Nick C; Schott, Jonathan M; Ourselin, Sebastien

    2015-12-01

    Structural MRI is widely used for investigating brain atrophy in many neurodegenerative disorders, with several research groups developing and publishing techniques to provide quantitative assessments of this longitudinal change. Often techniques are compared through computation of required sample size estimates for future clinical trials. However interpretation of such comparisons is rendered complex because, despite using the same publicly available cohorts, the various techniques have been assessed with different data exclusions and different statistical analysis models. We created the MIRIAD atrophy challenge in order to test various capabilities of atrophy measurement techniques. The data consisted of 69 subjects (46 Alzheimer's disease, 23 control) who were scanned multiple (up to twelve) times at nine visits over a follow-up period of one to two years, resulting in 708 total image sets. Nine participating groups from 6 countries completed the challenge by providing volumetric measurements of key structures (whole brain, lateral ventricle, left and right hippocampi) for each dataset and atrophy measurements of these structures for each time point pair (both forward and backward) of a given subject. From these results, we formally compared techniques using exactly the same dataset. First, we assessed the repeatability of each technique using rates obtained from short intervals where no measurable atrophy is expected. For those measures that provided direct measures of atrophy between pairs of images, we also assessed symmetry and transitivity. Then, we performed a statistical analysis in a consistent manner using linear mixed effect models. The models, one for repeated measures of volume made at multiple time-points and a second for repeated "direct" measures of change in brain volume, appropriately allowed for the correlation between measures made on the same subject and were shown to fit the data well. From these models, we obtained estimates of the

  8. A novel technique for rat liver transplantation using Quick Linker system: a preliminary result.

    Science.gov (United States)

    Oldani, Graziano; Maestri, Marcello; Gaspari, Annalisa; Lillo, Ettore; Angelastri, Giacomo; Lenti, Luca Matteo; Rademacher, Johannes; Alessiani, Mario; Dionigi, Paolo

    2008-10-01

    The clinical success of liver transplantation is founded upon years of experimental research. Since Kamada and colleagues developed the "two-cuff" technique, the rat has become the best model for extensive investigations. Although the Kamada technique is technically complex and not easy to master, it is still the mainstay of orthotopic liver transplantation in rodents. We have developed a modified three-cuff version of this technique that facilitates anastomosis and markedly reduces warm ischemia time. The new technique involves a set of five microinstruments (the Quick-Linker system) designed and manufactured by our group. It was tested in male Lewis rats (group 1, donors n = 10, recipients n = 10). The graft was explanted as usual and standard cuffs were attached to the portal vein and the supra- and infrahepatic vena cavae. Corresponding vessels in the recipient were isolated, and Quicker-Linker holding rings were attached to each. The vessels were then clamped and the native organ removed. Once the graft was positioned in the recipient's abdomen, the holding rings attached to the recipient vessels and the cuffs applied to graft vessels were automatically aligned and joined with the aid of a special alignment tool. Warm ischemia times were always inferior to 6 minutes. Survival at postoperative day 10 was 80%. Liver function was well preserved in all of the surviving rats. The Quick-Linker technique significantly shortens warm ischemia time and allows rapid anastomosis that is relatively independent of operator skill. It can be considered a reliable option for microsurgeons looking for quick results and high success rates.

  9. A Short-term Comparison Between Result of Palisade Cartilage Tympanoplasty and Temporalis Fascia Technique

    Directory of Open Access Journals (Sweden)

    Mahmood Shishegar

    2012-03-01

    Full Text Available Introduction: The use of cartilage as a grafting material has been advocated in cases where there is a high risk of graft failure, such as subtotal perforations, adhesive processes, and residual defects after primary tympanoplasties. The purpose of this study was to compare the graft acceptance rates and auditory outcomes of cartilage tympanoplasty operations using a palisade technique with those of primary tympanoplasty using temporalis fascia in a homogenous group of patients. Study Design: Prospective study.  Materials and Methods:The study population included 54 patients who were operated on in two groups (palisade technique & temporalis fascia technique with each group containing 27 patients. Patients with pure subtotal perforations (perforation of >50% of the whole tympanic membrane [TM] area, an intact ossicular chain, at least a one month dry period, and normal middle ear mucosa were included in the study. Grafts acceptance rates and pre- and post-operative audiograms were compared. The follow-up time was six months.  Results: Graft acceptance was achieved in all patients (100% in the palisade cartilage tympanoplasty group and in 25 patients (92.5% in the temporalis fascia group. This difference was not statistically significant (P= 0.15. Comparison of the increases in mean speech reception threshold, air–bone gap, and pure-tone average scores between both techniques showed no significant changes.    Conclusion: Our experience with the palisade cartilage technique demonstrates that subtotal or total perforation at high risk for graft failure can be treated efficiently, and that a durable and resistant reconstruction of the TM with reasonable auditory function can be achieved.  

  10. A short-term evaluation between the result of palisade cartilage tympanoplasty and temporalis fascia technique

    Directory of Open Access Journals (Sweden)

    Irfan Ul Shamas

    2014-01-01

    Full Text Available Introduction: The use of cartilage as a grafting material has been advocated in cases where there is a high risk of graft failure, such as subtotal perforations, adhesive processes, and residual defects after primary tympanoplasties. The purpose of this study was to compare the graft acceptance rates and auditory outcomes of cartilage tympanoplasty operations using a palisade technique with those of primary tympanoplasty using temporalis fascia in a homogenous group of patients. Study Design: Prospective study. Materials and Methods: The study population included 54 patients who were operated on in two groups (palisade technique and temporalis fascia technique with each group containing 27 patients. Patients with pure subtotal perforations (perforation of >50% of the whole tympanic membrane [TM] area, an intact ossicular chain, at least 1 month dry period, and normal middle ear mucosa were included in the study. Grafts acceptance rates and pre and postoperative audiograms were compared. The follow-up time was 6 months. Results: Graft acceptance was achieved in all patients (100% in the palisade cartilage tympanoplasty group and in 25 patients (92.5% in the temporalis fascia group. This difference was not statistically significant (P = 0.15. Comparison of the increases in mean speech reception threshold, air-bone gap, and pure-tone average scores between both techniques showed no significant changes. Conclusion: Our experience with the palisade cartilage technique demonstrates that subtotal or total perforation at high risk for graft failure can be treated efficiently, and that a durable and resistant reconstruction of the TM with reasonable auditory function can be achieved.

  11. Results of hip arthroplasty using Paavilainen technique in patients with congenitally dislocated hip

    Directory of Open Access Journals (Sweden)

    R. M. Tikhilov

    2014-01-01

    Full Text Available The purpose of the study was to analyze the medium- and long-term results of hip arthroplasty using Paavilainen technique in patients with the congenitally dislocated hip. Methods: From 2001 to 2012 180 operations were carried out were using the Paavilainen technique in 140 patients with high dislocation of the hip (Crowe IV. All patients were clinically evaluated using the Harris Hip Score (HHS, VAS and radiography. Statistical analysis was performed using the Pearson correlation coefficients, multiple regression analysis and classification trees analysis. Results: The average Harris score improved from preoperative 41.6 (40,3-43,5 to 79.3 (77,9-82,7 at final follow-up, and the difference was significant. Early complications were 9% (the most frequent were fractures of the proximal femur, later - 16.7% (pseudoarthrosis of the greater trochanter, 13.9%; disclocations-1,1%, aseptic loosening of the components - 1.7%, reoperation performed in 8.3% of cases. Such factors as age and limb length has statistically significant effect on functional outcomes. Established predictive model allows to get the best possible functional outcome in such patients with severe dysplasia. Conclusions: Total Hip arthroplasty using the Paavilainen technique is an effective method of surgical treatment in patients with the congenitally dislocated hip, but it is technically difficult operation with a high incidence of complications in comparison with standard primary total hip replacement.

  12. RESULTS OF THE USE OF PEEK CAGES IN THE TREATMENT OF BASILAR INVAGINATION BY GOEL TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Carelli Teixeira da Silva

    2016-03-01

    Full Text Available ABSTRACT Objective: Analysis of the use of polyetheretherketone (PEEK cages for atlantoaxial facet realignment and distraction for treatment of basilar invagination by Goel technique. Method: Retrospective descriptive statistical analysis of the neurological status, pain, presence of subsidence and bone fusion with the use of PEEK cages in 8 atlantoaxial joints of 4 patients with basilar invagination. All patients were treated with atlantoaxial facet distraction and realignment and subsequent arthrodesis C1-C2 by the technique of Goel modified by the use of PEEK cage. Results: All patients showed improvement in Nurick neurological assessment scale and Visual Analogue Scale (VAS of pain. There were no cases of subsidence, migration, or damage to the vertebral artery during the insertion of the cage. All joints evolved with bone fusion, assessed by dynamic radiographs, and computed tomography. Two patients developed neuropathic pain in dermatome of C2 and one patient had unilateral vertebral artery injury during C2 instrumentation treated with insertion of pedicle screw to control the bleeding. Conclusion: The results of the treatment of basilar invagination by the Goel technique with the use of PEEK cages shown to be effective and safe although further studies are needed to confirm this use.

  13. Techniques And Results For The Calibration Of The MST Prototype For The Cherenkov Telescope Array

    CERN Document Server

    ,

    2016-01-01

    The next generation instrument for ground-based gamma-ray astronomy will be the Cherenkov Telescope Array (CTA), consisting of approximately 100 telescopes in three sizes, built on two sites with one each in the Northern and Southern Hemi- spheres. Up to 40 of these will be Medium Size Telescopes (MSTs) which will dominate sensitivity in the core energy range. Since 2012, a full size mechanical prototype for the modified 12 m Davies-Cotton design MST has been in operation in Berlin. This doc- ument describes the techniques which have been implemented to calibrate and optimise the mechanical and optical performance of the prototype, and gives the results of over three years of observations and measurements. Pointing calibration techniques will be discussed, along with the development of a bending model, and calibration of the CCD cameras used for pointing measurements. Additionally alignment of mirror segments using the Bokeh method is shown.

  14. Indication, surgical technique and results of endoscopic fascial release in plantar fasciitis (E FRPF).

    Science.gov (United States)

    Jerosch, Jörg; Schunck, Jochem; Liebsch, Dietrich; Filler, Tim

    2004-09-01

    The purpose of the present study is to present the surgical technique for, and review our indications and results after, endoscopic fascial release in patients with plantar fasciitis. In five thiel-embalmed human specimens, a biportal technique for endoscopic release of the plantar fascia was established. The aim was here to evaluate the relation between the plantar fascia and the heel spur and to perform a release that would not exceed 50-70% of the diameter of the calcaneoplantar fascia. The endoscopic technique was performed within the last 5 years in ten male and seven female patients. All patients with the clinical entity of plantar fasciitis underwent conservative treatment for at least 6 months. The average age at surgery was 35 years (24-56 years). In the first five patients, surgery was performed under c-arm control. In all patients the operation could be finished endoscopically. The endoscopic portals healed without complications. The time for surgery during the learning curve ranged between 21 and 74 min (average 41 min) and was still longer compared to the open technique. The clinical follow-up ranged between 4 and 48 months (average 18.5 months). Out of 17 patients, 13 improved clinically, and they would choose the treatment option again. In the Ogilvie-Harris score, seven patients showed good and six excellent results. In two patients, the initial results were not satisfactory, because of a bony stress reaction of the calcaneus. This complication was treated by 6 weeks of partial weight bearing, without any further problems. Two other patients developed secondary pain in the lateral column. In spite of the minimal invasive approach it seems to be important to be careful in increasing the weight bearing in early rehabilitation. The technique of the endoscopic plantar fascia release (E FRPF) can be performed in a standardised and reproducible procedure. The follow-up examination showed good midterm results, but a loss of stability of the plantar arch

  15. Murillo's paintings revealed by spectroscopic techniques and dedicated laboratory-made micro X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Duran, A., E-mail: adrian@icmse.csic.es [Materials Science Institute of Seville, Avda Americo Vespucio 49, 41092 Seville (Spain); Centre de Recherche et de Restauration des Musees de France (C2RMF-CNRS), Palais du Louvre, 14 quai Francois Mitterrand, 75001 Paris (France); Siguenza, M.B.; Franquelo, M.L.; Haro, M.C. Jimenez de; Justo, A.; Perez-Rodriguez, J.L. [Materials Science Institute of Seville, Avda Americo Vespucio 49, 41092 Seville (Spain)

    2010-06-25

    This paper describes one of the first case studies using micro-diffraction laboratory-made systems to analyse painting cross-sections. Pigments, such as lead white, vermilion, red ochre, red lac, lapis lazuli, smalt, lead tin yellow type I, massicot, ivory black, lamp black and malachite, were detected in cross-sections prepared from six Bartolome Esteban Murillo paintings by micro-Raman and micro-XRD combined with complementary techniques (optical microscopy, SEM-EDS, and FT-IR). The use of micro-XRD was necessary due to the poor results obtained with conventional XRD. In some cases, pigment identification was only possible by combining results from the different analytical techniques utilised in this study.

  16. Pluto Revealed: First Results from the Historic 1st Fly-By Space Mission

    Science.gov (United States)

    Smith, Kimberly Ennico

    2015-01-01

    On July 14, 2015, after a 9.5 year trek across the solar system, NASAs New Horizons spacecraft successfully flew by the dwarf planet Pluto and its system of moons, taking imagery, spectra and in-situ particle data. Data obtained by New Horizons will address numerous outstanding questions on the geology and composition of Pluto and Charon, plus measurements of Plutos atmosphere, and provide revised understanding of the formation and evolution of Pluto and Charon and its smaller moons. This data set is an invaluable glimpse into the outer Third Zone of the Solar System. Data from the intense July 14th fly-by sequence will be downlinked to Earth over a period of 16 months, the duration set by the large data set (over 60 GBits), tempered by limited transmission bandwidth rates (1-2 kbps) and sharing the three 70m DSN assets. This presentation summarizes the New Horizons mission and early science results.

  17. Exoplanet hosts reveal lithium depletion: Results from a homogeneous statistical analysis

    CERN Document Server

    Figueira, P; Delgado-Mena, E; Adibekyan, V Zh; Sousa, S G; Santos, N C; Israelian, G

    2014-01-01

    Aims. We study the impact of the presence of planets on the lithium abundance of host stars and evaluate the previous claim that planet hosts exhibit lithium depletion when compared to their non-host counterparts. Methods. Using previously published lithium abundances, we remove the confounding effect of the different fundamental stellar parameters by applying a multivariable regression on our dataset. In doing so, we explicitly make an assumption made implicitly by different authors: that lithium abundance depends linearly on fundamental stellar parameters. Using a moderator variable to distinguish stars with planets from those without, we evaluate the existence of an offset in lithium abundances between the two groups. We perform this analysis first for stars that present a clear lithium detection exclusively and include in a second analysis upper lithium measurements. Results. Our analysis shows that under the above-mentioned assumption of linearity, a statistically significant negative offset in lithium a...

  18. Radiation Hardening by Software Techniques on FPGAs: Flight Experiment Evaluation and Results

    Science.gov (United States)

    Schmidt, Andrew G.; Flatley, Thomas

    2017-01-01

    We present our work on implementing Radiation Hardening by Software (RHBSW) techniques on the Xilinx Virtex5 FPGAs PowerPC 440 processors on the SpaceCube 2.0 platform. The techniques have been matured and tested through simulation modeling, fault emulation, laser fault injection and now in a flight experiment, as part of the Space Test Program- Houston 4-ISS SpaceCube Experiment 2.0 (STP-H4-ISE 2.0). This work leverages concepts such as heartbeat monitoring, control flow assertions, and checkpointing, commonly used in the High Performance Computing industry, and adapts them for use in remote sensing embedded systems. These techniques are extremely low overhead (typically software, remotely uploading the new experiment to the ISS SpaceCube 2.0 platform, and conducting the experiment continuously for 16 days before the platform was decommissioned. The experiment was conducted on two PowerPCs embedded within the Virtex5 FPGA devices and the experiment collected 19,400 checkpoints, processed 253,482 status messages, and incurred 0 faults. These results are highly encouraging and future work is looking into longer duration testing as part of the STP-H5 flight experiment.

  19. Variances in the projections, resulting from CLIMEX, Boosted Regression Trees and Random Forests techniques

    Science.gov (United States)

    Shabani, Farzin; Kumar, Lalit; Solhjouy-fard, Samaneh

    2016-05-01

    The aim of this study was to have a comparative investigation and evaluation of the capabilities of correlative and mechanistic modeling processes, applied to the projection of future distributions of date palm in novel environments and to establish a method of minimizing uncertainty in the projections of differing techniques. The location of this study on a global scale is in Middle Eastern Countries. We compared the mechanistic model CLIMEX (CL) with the correlative models MaxEnt (MX), Boosted Regression Trees (BRT), and Random Forests (RF) to project current and future distributions of date palm (Phoenix dactylifera L.). The Global Climate Model (GCM), the CSIRO-Mk3.0 (CS) using the A2 emissions scenario, was selected for making projections. Both indigenous and alien distribution data of the species were utilized in the modeling process. The common areas predicted by MX, BRT, RF, and CL from the CS GCM were extracted and compared to ascertain projection uncertainty levels of each individual technique. The common areas identified by all four modeling techniques were used to produce a map indicating suitable and unsuitable areas for date palm cultivation for Middle Eastern countries, for the present and the year 2100. The four different modeling approaches predict fairly different distributions. Projections from CL were more conservative than from MX. The BRT and RF were the most conservative methods in terms of projections for the current time. The combination of the final CL and MX projections for the present and 2100 provide higher certainty concerning those areas that will become highly suitable for future date palm cultivation. According to the four models, cold, hot, and wet stress, with differences on a regional basis, appears to be the major restrictions on future date palm distribution. The results demonstrate variances in the projections, resulting from different techniques. The assessment and interpretation of model projections requires reservations

  20. Variances in the projections, resulting from CLIMEX, Boosted Regression Trees and Random Forests techniques

    Science.gov (United States)

    Shabani, Farzin; Kumar, Lalit; Solhjouy-fard, Samaneh

    2017-08-01

    The aim of this study was to have a comparative investigation and evaluation of the capabilities of correlative and mechanistic modeling processes, applied to the projection of future distributions of date palm in novel environments and to establish a method of minimizing uncertainty in the projections of differing techniques. The location of this study on a global scale is in Middle Eastern Countries. We compared the mechanistic model CLIMEX (CL) with the correlative models MaxEnt (MX), Boosted Regression Trees (BRT), and Random Forests (RF) to project current and future distributions of date palm ( Phoenix dactylifera L.). The Global Climate Model (GCM), the CSIRO-Mk3.0 (CS) using the A2 emissions scenario, was selected for making projections. Both indigenous and alien distribution data of the species were utilized in the modeling process. The common areas predicted by MX, BRT, RF, and CL from the CS GCM were extracted and compared to ascertain projection uncertainty levels of each individual technique. The common areas identified by all four modeling techniques were used to produce a map indicating suitable and unsuitable areas for date palm cultivation for Middle Eastern countries, for the present and the year 2100. The four different modeling approaches predict fairly different distributions. Projections from CL were more conservative than from MX. The BRT and RF were the most conservative methods in terms of projections for the current time. The combination of the final CL and MX projections for the present and 2100 provide higher certainty concerning those areas that will become highly suitable for future date palm cultivation. According to the four models, cold, hot, and wet stress, with differences on a regional basis, appears to be the major restrictions on future date palm distribution. The results demonstrate variances in the projections, resulting from different techniques. The assessment and interpretation of model projections requires reservations

  1. Results of an ECE Varying Degrees of Corrosion and Time of Application of the Technique

    Directory of Open Access Journals (Sweden)

    Espericueta-González D.E.

    2012-10-01

    Full Text Available The objective of the Electrochemical Chloride Extraction (ECE is to remove the chloride ions (Cl- which are embedded in concrete, since these ions are considered to result in accelerating the process of corrosion in steel reinforcement. The ECE is an electrochemical technique in which ions Cl- are transported to the outside of the concrete by means of an electric field. In this paper we present the results of mortar samples made in the laboratory. The specimens were previously contaminated with 2% NaCl by mass of cement, and stored in water curing tanks at constant laboratory of 95% RH for one and sixty days. Afterward, mortars underwent an ECE in times of 15, 30 and 60 days of treatment. The results obtained under these conditions show that increasing the duration of the ECE will get a higher amount of Cl-ions removed from the mortar. It should be noted that the extent of the corroded reinforcement is a critical variable in the effectiveness of the technique.

  2. Supramalleolar osteotomies for degenerative joint disease of the ankle joint: indication, technique and results.

    Science.gov (United States)

    Barg, Alexej; Pagenstert, Geert I; Horisberger, Monika; Paul, Jochen; Gloyer, Marcel; Henninger, Heath B; Valderrabano, Victor

    2013-09-01

    Patients with varus or valgus hindfoot deformities usually present with asymmetric ankle osteoarthritis. In-vitro biomechanical studies have shown that varus or valgus hindfoot deformity may lead to altered load distribution in the tibiotalar joint which may result in medial (varus) or lateral (valgus) tibiotalar joint degeneration in the short or medium term. The treatment of asymmetric ankle osteoarthritis remains challenging, because more than half of the tibiotalar joint surface is usually preserved. Therefore, joint-sacrificing procedures like total ankle replacement or ankle arthrodesis may not be the most appropriate treatment options. The shortand midterm results following realignment surgery, are very promising with substantial pain relief and functional improvement observed post-operatively. In this review article we describe the indications, surgical techniques, and results from of realignment surgery of the ankle joint in the current literature.

  3. LONG TERM FOLLOW UP RESULTS OF RUPTURE TENDO CALCANEUM TREATED BY LINDHOLM TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Sibaji

    2015-11-01

    Full Text Available INTRODUCTION: Rupture of tendon calcaneum is a common problem.There are proponents of both conservative and operative methods.Inadequate strength and re ruptures are frequent. To address both the problems we have chosen Lindholm technique and doing it for last 20 yrs with very good results. MATERIALS AND METHODS: From January 1994 to August 2013, 112 consecutive patients were treated by this method, 85 cases were fresh ruptures, 23 were neglected ruptures and four cases were re rupture after operation done elsewhere. Torn tendo calcaneum was repaired by Kessler suture, it was then augmented with two 8cm by 1cm turn down flap of gastrosoleus apponeurosis. Skin suture was done with utmost care. BK pop cast was done in equinus position of ankle for four weeks, followed by gradual weight bearing with heel raised shoe for six months. RESULTS: All patients went back to their pre injury activity level. In four patients there were superficial skin infection which healed without skin necrosis. One patient needed rotation flap. Evaluation was done by modified Rupp score. It was found to be excellent in 47% cases good in 43% cases and fair in 8% cases. CONCLUSION: Lindholm technique was originally described for neglected cases, we used it in all cases to avoid any complication in fresh cases and found it universally successful.

  4. What Do the California Standards Test Results Reveal about the Movement toward Eighth-Grade Algebra for All?

    Science.gov (United States)

    Liang, Jian-Hua; Heckman, Paul E.; Abedi, Jamal

    2012-01-01

    In California, an increasing number of 8th graders have taken algebra courses since 2003. This study examines students' California Standards Test (CST) results in grades 7 through 11, aiming to reveal who took the CST for Algebra I in 8th grade and whether the increase has led to a rise in students' taking higher-level mathematics CSTs and an…

  5. What Do the California Standards Test Results Reveal about the Movement toward Eighth-Grade Algebra for All?

    Science.gov (United States)

    Liang, Jian-Hua; Heckman, Paul E.; Abedi, Jamal

    2012-01-01

    In California, an increasing number of 8th graders have taken algebra courses since 2003. This study examines students' California Standards Test (CST) results in grades 7 through 11, aiming to reveal who took the CST for Algebra I in 8th grade and whether the increase has led to a rise in students' taking higher-level mathematics CSTs and an…

  6. Numerical modelling of radon-222 entry into houses: An outline of techniques and results

    DEFF Research Database (Denmark)

    Andersen, C.E.

    2001-01-01

    Numerical modelling is a powerful tool for studies of soil gas and radon-222 entry into houses. It is the purpose of this paper to review some main techniques and results. In the past, modelling has focused on Darcy flow of soil gas (driven by indoor–outdoor pressure differences) and combined...... diffusive and advective transport of radon. Models of different complexity have been used. The simpler ones are finite-difference models with one or two spatial dimensions. The more complex models allow for full three-dimensional and time dependency. Advanced features include: soil heterogeneity, anisotropy......, fractures, moisture, non-uniform soil temperature, non-Darcy flow of gas, and flow caused by changes in the atmospheric pressure. Numerical models can be used to estimate the importance of specific factors for radon entry. Models are also helpful when results obtained in special laboratory or test structure...

  7. Comparison of NDT techniques to evaluate CFRP. Results obtained in a MAIzfp round robin test

    Energy Technology Data Exchange (ETDEWEB)

    Grosse, Christian U. [Technische Univ. Muenchen (Germany). Chair of Non-destructive Testing; Goldammer, Matthias; Grager, Jan-Carl [Siemens AG Corporate Technology, Muenchen (Germany); and others

    2016-10-01

    Fiber reinforced polymeric materials are used for lightweight constructions and are an integral part of cars, airplanes or rotor blades of wind turbines. Nondestructive testing (NDT) methods play an increasing role concerning the manufacturing process and the inspection during lifetime. The selection of the best NDT technique for a certain application depends - of course - on many factors including the type, position and size of the defect to be detected but also on secondary issues like accessibility, automation, testing costs, reliability and resolution to mention only some. For the more technical-scientific part of these issues, the determination of the probability of detection (PoD) plays a significant role. Early in the design process questions should be raised concerning the probability with which certain attribute of interest (a defect that has an effect on the structural behavior) can be detected (and localized) in a certain construction. Several defect types have been identified to be critical like impact damages, undulations and porosity. Test samples out of differently processed Carbon Fiber-Reinforced Polymers (CFRP) as used in the automotive or aeronautical industry have been produced including defects of different type and size. In order to determine the PoD and to check whether a technique is applicable the different partners applied a broad variety of selected NDT techniques including Micro CT, Ultrasound (including phased-array and air-coupled UT), Active Thermography, Eddy Current, Vibration and Visual Analysis and Local Acoustic Resonance Spectroscopy (LARS). The presentation will summarize some of the results of the experiments and ongoing data analysis.

  8. Laparoscopic vasectomy in African savannah elephant (Loxodonta africana); surgical technique and results.

    Science.gov (United States)

    Marais, Hendrik J; Hendrickson, Dean A; Stetter, Mark; Zuba, Jeffery R; Penning, Mark; Siegal-Willott, Jess; Hardy, Christine

    2013-12-01

    Several small, enclosed reserves in southern Africa are experiencing significant elephant population growth, which has resulted in associated environmental damage and changes in biodiversity. Although several techniques exist to control elephant populations, e.g., culling, relocation, and immunocontraception, the technique of laparoscopic vasectomy of free-ranging bull elephants was investigated. Bilateral vasectomies were performed in 45 elephants. Of these elephants, one died within 24 hr of recovery and two had complications during surgery but recovered uneventfully. Histologic examination confirmed the resected tissue as ductus deferens in all the bulls. Most animals recovered uneventfully and showed no abnormal behavior after surgery. Complications recorded included incisional dehiscence, 1 full-thickness and 2 partial-thickness lacerations of the large intestine, and initial sling-associated complications, for example, deep radial nerve paresis. One bull was found dead 6 weeks after surgery without showing any prior abnormal signs. Vasectomy in free-ranging African bull elephants may be effectively performed in their normal environment. The surgical procedure can be used as a realistic population management tool in free-ranging elephants without major anesthetic, surgical, or postoperative complications.

  9. Creation of a Neovagina by Laparoscopic Modified Vecchietti Technique: Anatomic and Functional Results.

    Science.gov (United States)

    Baptista, Eduardo; Carvalho, Giselda; Nobre, Carlos; Dias, Isabel; Torgal, Isabel

    2016-09-01

    Purpose To evaluate the anatomic and functional results of a laparoscopic modified Vecchietti technique for the creation of a neovagina in patients with congenital vaginal aplasia. Methods Retrospective study of nine patients with congenital vaginal aplasia submitted to the laparoscopic Vecchietti procedure, in our department, between 2006 and 2013. The anatomical results were evaluated by assessing the length, width and epithelialization of the neovagina at the postoperative visits. The functional outcome was evaluated using the Rosen Female Sexual Function Index (FSFI) questionnaire and comparing the patients' results to those of a control group of 20 healthy women. The statistical analysis was performed using SPSS Statistics version 19.0 (IBM, Armonk, NY, USA), Student t-test, Mann-Whitney U test and Fisher exact test. Results The condition underlying the vaginal aplasia was Mayer-Rokitansky-Küster-Hauser syndrome in eight cases, and androgen insensitivity syndrome in one case. The average preoperative vaginal length was 2.9 cm. At surgery, the mean age of the patients was 22.2 years. The surgery was performed successfully in all patients and no intra or postoperative complications were recorded. At the first postoperative visit (6 to 8 weeks after surgery), the mean vaginal length was 8.1 cm. In all cases, the neovagina was epithelialized and had an appropriate width. The mean FSFI total and single domain scores did not differ significantly from those of the control group: 27.5 vs. 30.6 (total); 4.0 vs. 4.2 (desire); 4.4 vs. 5.2 (arousal); 5.2 vs. 5.3 (lubrication); 4.2 vs. 5.0 (orgasm); 5.3 vs. 5.5 (satisfaction) and 4.4 vs. 5.4 (comfort). Conclusions This modified laparoscopic Vecchietti technique is a simple, safe and effective procedure, which allows patients with congenital vaginal aplasia to have a satisfactory sexual activity, comparable to that of normal controls.

  10. Results of Patello-Tibial Cerclage Wire Technique for Comminuted Patella Fractures Treated with Partial Patellectomy

    Directory of Open Access Journals (Sweden)

    Ender Alagöz

    2014-12-01

    Full Text Available Aim: Partial patellectomy and patellotibial cerclage technique used in comminuted inferior pole patellar fractures were evaluated and the results were discussed. Methods: Thirteen patients who have undergone partial distal patellar excision were evaluated in the study. In all patients, the inferior pole of the patella was resected, patellar tendon was sutured to the proximal patellar fragment and patellotibial cerclage was performed. At the last visit, the patients were evaluated using measurement of the distance between the superior pole of the patella and the tibial tubercle, the Lysholm knee scoring scale, knee range of motion and thigh circumference measurement. Results: The mean flexion value was 131.10 (±4.6 in normal knees and 117.20 (±8.0 in operated knees. The mean thigh diameter was 49.5 (±3.7 cm and 46.4 (±4.5 cm in normal knees and in operated knees, respectively. The mean Lysholm knee score in the patient group was 84.3 (±17.1 points. The mean distance between the superior pole of the patella and the tibial tubercle was 10.6 (±1.0 cm in normal knees and 10.1 (±1.2 cm in operated knees. The exstensor mechanism was intact in all patients and no revision surgery was performed. Conclusion: Patellotibial cerclage technique performed after partial patellectomy permits early motion and protects patients from harmful effects of immobilization; and good functional results are obtained if patients start early knee motion.

  11. Seasonal differences in the subjective assessment of outdoor thermal conditions and the impact of analysis techniques on the obtained results

    Science.gov (United States)

    Kántor, Noémi; Kovács, Attila; Takács, Ágnes

    2016-11-01

    Wide research attention has been paid in the last two decades to the thermal comfort conditions of different outdoor and semi-outdoor urban spaces. Field studies were conducted in a wide range of geographical regions in order to investigate the relationship between the thermal sensation of people and thermal comfort indices. Researchers found that the original threshold values of these indices did not describe precisely the actual thermal sensation patterns of subjects, and they reported neutral temperatures that vary among nations and with time of the year. For that reason, thresholds of some objective indices were rescaled and new thermal comfort categories were defined. This research investigates the outdoor thermal perception patterns of Hungarians regarding the Physiologically Equivalent Temperature ( PET) index, based on more than 5800 questionnaires. The surveys were conducted in the city of Szeged on 78 days in spring, summer, and autumn. Various, frequently applied analysis approaches (simple descriptive technique, regression analysis, and probit models) were adopted to reveal seasonal differences in the thermal assessment of people. Thermal sensitivity and neutral temperatures were found to be significantly different, especially between summer and the two transient seasons. Challenges of international comparison are also emphasized, since the results prove that neutral temperatures obtained through different analysis techniques may be considerably different. The outcomes of this study underline the importance of the development of standard measurement and analysis methodologies in order to make future studies comprehensible, hereby facilitating the broadening of the common scientific knowledge about outdoor thermal comfort.

  12. Seasonal differences in the subjective assessment of outdoor thermal conditions and the impact of analysis techniques on the obtained results.

    Science.gov (United States)

    Kántor, Noémi; Kovács, Attila; Takács, Ágnes

    2016-11-01

    Wide research attention has been paid in the last two decades to the thermal comfort conditions of different outdoor and semi-outdoor urban spaces. Field studies were conducted in a wide range of geographical regions in order to investigate the relationship between the thermal sensation of people and thermal comfort indices. Researchers found that the original threshold values of these indices did not describe precisely the actual thermal sensation patterns of subjects, and they reported neutral temperatures that vary among nations and with time of the year. For that reason, thresholds of some objective indices were rescaled and new thermal comfort categories were defined. This research investigates the outdoor thermal perception patterns of Hungarians regarding the Physiologically Equivalent Temperature (PET) index, based on more than 5800 questionnaires. The surveys were conducted in the city of Szeged on 78 days in spring, summer, and autumn. Various, frequently applied analysis approaches (simple descriptive technique, regression analysis, and probit models) were adopted to reveal seasonal differences in the thermal assessment of people. Thermal sensitivity and neutral temperatures were found to be significantly different, especially between summer and the two transient seasons. Challenges of international comparison are also emphasized, since the results prove that neutral temperatures obtained through different analysis techniques may be considerably different. The outcomes of this study underline the importance of the development of standard measurement and analysis methodologies in order to make future studies comprehensible, hereby facilitating the broadening of the common scientific knowledge about outdoor thermal comfort.

  13. Cardiac CT for the assessment of chest pain: Imaging techniques and clinical results

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Hans-Christoph, E-mail: christoph.becker@med.uni-muenchen.de [Ludwig-Maximilians-University, Grosshadern Clinic, Department of Clinical Radiology, Marchioninistr. 15, 81377 Munich (Germany); Johnson, Thorsten [Ludwig-Maximilians-University, Grosshadern Clinic, Department of Clinical Radiology, Marchioninistr. 15, 81377 Munich (Germany)

    2012-12-15

    Immediate and efficient risk stratification and management of patients with acute chest pain in the emergency department is challenging. Traditional management of these patients includes serial ECG, laboratory tests and further on radionuclide perfusion imaging or ECG treadmill testing. Due to the advances of multi-detector CT technology, dedicated coronary CT angiography provides the potential to rapidly and reliably diagnose or exclude acute coronary artery disease. Life-threatening causes of chest pain, such as aortic dissection and pulmonary embolism can simultaneously be assessed with a single scan, sometimes referred to as “triple rule out” scan. With appropriate patient selection, cardiac CT can accurately diagnose heart disease or other sources of chest pain, markedly decrease health care costs, and reliably predict clinical outcomes. This article reviews imaging techniques and clinical results for CT been used to evaluate patients with chest pain entering the emergency department.

  14. An evaluation of the partial reflection technique and results from the winter 1971 - 1972 D region

    Science.gov (United States)

    Dasilva, L. C.; Bowhill, S. A.

    1974-01-01

    Fundamental physical and chemical processes, and measurement techniques on the D region are reviewed. Design considerations about a partial-reflection system are made, and the main characteristics of the partial-reflection system at the University of Illinois are presented. The nature of the partial reflections is discussed, particularly reflections produced by gradients in electron density and by random fluctuations in a locally homogeneous random medium. Possible reasons for disagreement between partial reflections and rocket measurements are discussed. Some suggestions are made to improve partial-reflection data reduction, including the use of only maximums of the reflections and deconvolution of the data. The results of partial-reflection measurements at Wallops Island, Virginia during the 1971-1972 winter are presented and compared to rocket measurements.

  15. Data Assimilation Techniques for Ionospheric Reference Scenarios - project overview and first results

    Science.gov (United States)

    Gerzen, Tatjana; Mainul Hoque, M.; Wilken, Volker; Minkwitz, David; Schlüter, Stefan

    2015-04-01

    this technique for the generation of IRSs covering the EGNOS V3 service area. This presentation gives an overview about the DAIS project and the first results. We outline the assimilation approach, show test run results and finally address and discuss open questions.

  16. Competitive elite golf: a review of the relationships between playing results, technique and physique.

    Science.gov (United States)

    Hellström, John

    2009-01-01

    Elite golfers commonly use fitness and technical training to become more competitive. The aim of this paper was to review the literature regarding the relationships between elite golfers' playing results, technique and physique. The competitive outcome is a direct function of the score. The three golf statistical measures that show the strongest correlations to scoring average are greens in regulation (GIR), scrambling, and putts per GIR. However, more detailed game statistics are needed where the distances to the targets are known before and after the strokes. Players affect ball displacement by controlling clubhead velocity and clubface angle during club and ball impact. X-factor studies have produced ambiguous results, possibly caused by different definitions of upper torso, rotation and top of backswing. Higher clubhead speed is generally associated with larger spinal rotation and shoulder girdle protraction at the top of the backswing. It is also associated with higher ground reaction forces and torques, a bottom-up and sequential increase of body segment angular velocities, a rapid increase of spinal rotation and a late adduction of the wrists during the downswing. Players can increase the clubhead speed generated by a swinging motion by actively adding a force couple. Wrist, elbow and shoulder force couple strategies should be differentiated when investigating the technique. Physical parameters such as anthropometrics, strength and flexibility are associated with skill level and clubhead speed. Current studies have investigated the linear correlation between arm and shaft lengths and clubhead speed, but a quadratic relationship may be stronger due to changes in moment of inertia. Fitness training can increase and perhaps decrease the clubhead speed and striking distance, depending on training methods and the player's fitness and level of skill. Future studies may focus on individual training needs and the relationship between physique, execution and its

  17. Antegrade scrotal sclerotherapy of internal spermatic veins for varicocele treatment: technique, complications, and results

    Directory of Open Access Journals (Sweden)

    Alessandro Crestani

    2016-01-01

    Full Text Available Varicocele repair is mainly indicated in young adult patients with clinical palpable varicocele and abnormal semen parameters. Varicocele treatment is associated with a significant improvement in sperm concentration, motility, morphology, and pregnancy rate. Antegrade scrotal sclerotherapy (ASS represented one of the main alternatives to the traditional inguinal or suprainguinal surgical ligation. This article reviews the use of ASS for varicocele treatment. We provide a brief overview of the history of the procedure and present our methods used in ASS. In addition, we review complication and success of ASS, including our own retrospective data of treating 674 patients over the last 17 years. Herein, we analyzed step by step the ASS technique and described our results with an original modified technique with a long follow-up. Between December 1997 and December 2014, we performed 674 ASS. Mean operative time was 14 min (range 9 to 50 min. No significant intraoperative complications were reported. Within 90 days from the procedure, postoperative complications were recorded in overall 49 (7.2% patients. No major complications were recorded. A persistent/recurrent varicocele was detected in 40 (5.9% cases. In 32/40 (80% cases, patients showed preoperative grade III varicoceles. In patients with a low sperm number before surgery, sperm count improved from 13 × 10 6 to 21 × 10 6 ml−1 (P < 0.001. The median value of the percentage of progressive motile forms at 1 h improved from 25% to 45% (P < 0.001. Percentage of normal forms increased from 17% before surgery to 35% 1 year after the procedure (P < 0.001. In the subgroup of the 168 infertile patients, 52 (31% fathered offspring at a 12-month-minimum follow-up. Therefore, ASS is an effective minimal invasive treatment for varicocele with low recurrence/persistence rate.

  18. Photolysis frequency measurement techniques: results of a comparison within the ACCENT project

    Directory of Open Access Journals (Sweden)

    K. C. Clemitshaw

    2008-09-01

    Full Text Available An intercomparison of different radiometric techniques measuring atmospheric photolysis frequencies j(NO2, j(HCHO and j(O1D was carried out in a two-week field campaign in June 2005 at Jülich, Germany. Three double-monochromator based spectroradiometers (DM-SR, three single-monochromator based spectroradiometers with diode-array detectors (SM-SR and seventeen filter radiometers (FR (ten j(NO2-FR, seven j(O1D-FR took part in this comparison. For j(NO2, all spectroradiometer results agreed within ±3%. For j(HCHO, agreement was slightly poorer between −8% and +4% of the DM-SR reference result. For the SM-SR deviations were explained by poorer spectral resolutions and lower accuracies caused by decreased sensitivities of the photodiode arrays in a wavelength range below 350 nm. For j(O1D, the results were more complex within +8% and −4% with increasing deviations towards larger solar zenith angles for the SM-SR. The direction and the magnitude of the deviations were dependent on the technique of background determination. All j(NO2-FR showed good linearity with single calibration factors being sufficient to convert from output voltages to j(NO2. Measurements were feasible until sunset and comparison with previous calibrations showed good long-term stability. For the j(O1D-FR, conversion from output voltages to j(O1D needed calibration factors and correction functions considering the influences of total ozone column and elevation of the sun. All instruments showed good linearity at photolysis frequencies exceeding about 10% of maximum values. At larger solar zenith angles, the agreement was non-uniform with deviations explainable by insufficient correction functions. Comparison with previous calibrations for some j(O1D-FR indicated

  19. Changes in selected biochemical indices resulting from various pre-sampling handling techniques in broilers.

    Science.gov (United States)

    Chloupek, Petr; Bedanova, Iveta; Chloupek, Jan; Vecerek, Vladimir

    2011-05-13

    Since it is not yet clear whether it is possible to satisfactorily avoid sampling-induced stress interference in poultry, more studies on the pattern of physiological response and detailed quantification of stress connected with the first few minutes of capture and pre-sampling handling in poultry are required. This study focused on detection of changes in the corticosterone level and concentrations of other selected biochemical parameters in broilers handled in two different manners during blood sampling (involving catching, carrying, restraint, and blood collection itself) that lasted for various time periods within the interval 30-180 seconds. Stress effects of pre-sampling handling were studied in a group (n = 144) of unsexed ROSS 308 broiler chickens aged 42 d. Handling (catching, carrying, restraint, and blood sampling itself) was carried out in a gentle (caught, held and carried carefully in an upright position) or rough (caught by the leg, held and carried with lack of care in inverted position) manner and lasted for 30 s, 60 s, 90 s, 120 s, 150 s, and 180 s. Plasma corticosterone, albumin, glucose, cholesterol, lactate, triglycerides and total protein were measured in order to assess the stress-induced changes to these biochemical indices following handling in the first few minutes of capture. Pre-sampling handling in a rough manner resulted in considerably higher plasma concentrations of all biochemical indices monitored when compared with gentle handling. Concentrations of plasma corticosterone after 150 and 180 s of handling were considerably higher (P technique. Concentrations of plasma lactate were also increased by prolonged handling duration. Handling for 90-180 seconds resulted in a highly significant elevation of lactate concentration in comparison with 30 s handling regardless of handling technique. Similarly to corticosterone concentrations, a strong positive correlation was found between plasma lactate and duration of pre-sampling handling

  20. A Morphing Technique Applied to Lung Motions in Radiotherapy: Preliminary Results

    Directory of Open Access Journals (Sweden)

    R. Laurent

    2010-01-01

    Full Text Available Organ motion leads to dosimetric uncertainties during a patient’s treatment. Much work has been done to quantify the dosimetric effects of lung movement during radiation treatment. There is a particular need for a good description and prediction of organ motion. To describe lung motion more precisely, we have examined the possibility of using a computer technique: a morphing algorithm. Morphing is an iterative method which consists of blending one image into another image. To evaluate the use of morphing, Four Dimensions Computed Tomography (4DCT acquisition of a patient was performed. The lungs were automatically segmented for different phases, and morphing was performed using the end-inspiration and the end-expiration phase scans only. Intermediate morphing files were compared with 4DCT intermediate images. The results showed good agreement between morphing images and 4DCT images: fewer than 2 % of the 512 by 256 voxels were wrongly classified as belonging/not belonging to a lung section. This paper presents preliminary results, and our morphing algorithm needs improvement. We can infer that morphing offers considerable advantages in terms of radiation protection of the patient during the diagnosis phase, handling of artifacts, definition of organ contours and description of organ motion.

  1. Arthroscopic repair of combined Bankart and SLAP lesions: operative techniques and clinical results.

    Science.gov (United States)

    Cho, Hyung Lae; Lee, Choon Key; Hwang, Tae Hyok; Suh, Kuen Tak; Park, Jong Won

    2010-03-01

    To evaluate the clinical results and operation technique of arthroscopic repair of combined Bankart and superior labrum anterior to posterior (SLAP) lesions, all of which had an anterior-inferior Bankart lesion that continued superiorly to include separation of the biceps anchor in the patients presenting recurrent shoulder dislocations. From May 2003 to January 2006, we reviewed 15 cases with combined Bankart and SLAP lesions among 62 patients with recurrent shoulder dislocations who underwent arthroscopic repair. The average age at surgery was 24.2 years (range, 16 to 38 years), with an average follow-up period of 15 months (range, 13 to 28 months). During the operation, we repaired the unstable SLAP lesion first with absorbable suture anchors and then also repaired Bankart lesion from the inferior to superior fashion. We analyzed the preoperative and postoperative results by visual analogue scale (VAS) for pain, the range of motion, American Shoulder and Elbow Surgeon (ASES) and Rowe shoulder scoring systems. We compared the results with the isolated Bankart lesion. VAS for pain was decreased from preoperative 4.9 to postoperative 1.9. Mean ASES and Rowe shoulder scores were improved from preoperative 56.4 and 33.7 to postoperative 91.8 and 94.1, respectively. There were no specific complication and no significant limitation of motion more than 10 degree at final follow-up. We found the range of motions after the arthroscopic repair in combined lesions were gained more slowly than in patients with isolated Bankart lesions. In recurrent dislocation of the shoulder with combined Bankart and SLAP lesion, arthroscopic repair using absorbable suture anchors produced favorable clinical results. Although it has technical difficulty, the concomitant unstable SLAP lesion should be repaired in a manner that stabilizes the glenohumeral joint, as the Bankart lesion can be repaired if the unstable SLAP lesion is repaired first.

  2. Técnica de suturas ajustables: Resultados Technique of adjustable sutures: Results

    Directory of Open Access Journals (Sweden)

    Lourdes R. Hernández Santos

    2001-06-01

    Full Text Available Se realizó un estudio sensorial y motor preoperatorio y posoperatorio a 84 pacientes que acudieron a la consulta de Visión Binocular con el diagnóstico de estrabismo horizontal a partir de los 13 años de edad. El método estadístico utilizado fue "t" o Chi cuadrado. Nos trazamos como objetivo determinar los resultados posoperatorios de la cirugía de estrabismo realizada con la técnica de suturas ajustables, que fueron los siguientes: el 61 % de los pacientes con exotropía y el 71,4 % con el diagnóstico de exotropía se encontraban en ortotropía a los 6 meses de la intervención. El 71,4 % de los pacientes con esotropía y el 83,3 % con el diagnóstico de esotropía se encontraban en ortotropía al año de la intervención. Esta técnica quirúrgica permite la modificación de la desviación en el posoperatorio inmediato.A preoperative and postoperative sensorial and motor study was conducted among 84 patients who received attention at the consultation room of Binocular Vision with the diagnosis of horizontal strabismus from the age of 13 years old on. The statistical method used was "t" or chi square test. Our objective was to determine the postoperative results of the strabismus surgery performed by the technique of adjustable sutures. The results were as follows: 61 % of the patients with exotropia and 71.4 % with the diagnosis of exotropia were in orthotropia 6 months after the operation. 71.4 % of the patients with exotropia and 83.3 % with the diagnosis of exotropia were in orthotropia a year after the operation. This surgical technique allows the modification of the deviation in the immediate postoperative.

  3. Ambiguities in results obtained with 2D gel replicon mapping techniques

    NARCIS (Netherlands)

    Linskens, Maarten H.K.; Huberman, Joel A.

    1990-01-01

    Recently, two 2-dimensional (2D) gel techniques, termed neutral/neutral and neutral/alkaline, have been developed and employed to map replication origins in eukaryotic plasmids and chromosomal DNA. The neutral/neutral technique, which requires less DNA for analysis, has been preferentially used in r

  4. Fusing Observations and Model Results for Creation of Enhanced Ozone Spatial Fields: Comparison of Three Techniques

    Science.gov (United States)

    This paper presents three simple techniques for fusing observations and numerical model predictions. The techniques rely on model/observation bias being considered either as error free, or containing some uncertainty, the latter mitigated with a Kalman filter approach or a spati...

  5. Total cysto-prostatectomy: Technique description and results in 2 dogs.

    Science.gov (United States)

    Bacon, Nicholas; Souza, Carlos H de M; Franz, Sarah

    2016-02-01

    We describe a novel technique for total cysto-prostatectomy, followed by uretero-urethral anastomosis in 2 dogs. The technique was successful and was performed without pubic osteotomy. Post-operative urinary tract infections may be a potentially serious event.

  6. Proximal gastric vagotomy: effects of two operative techniques on clinical and gastric secretory results.

    Science.gov (United States)

    Hallenbeck, G A; Gleysteen, J J; Aldrete, J S; Slaughter, R L

    1976-01-01

    PGV performed in 39 patients by separating the lesser omentum from the stomach beginning 6 or 7 cm proximal to the pylorus and skeletonizing the distal 1 to 2 cm of esophagus was followed by 15.4% of proven and 10.2 of suspected recurrent ulcers. Insulin tests were done during the first 3 months postoperatively on 31 of the patients, including the 6 with proven and the 4 with suspected recurrent ulcers. The peak acid output to insulin minus tha basal acid output (PAOI-BAO) was less than 5 mEq/hr in 16 cases (52%) and from 5 to 25 mEq/hr in the remaining 15 cases. In 6 patients with proven recurrent ulcer, PAOI-BAO averaged 21.9 mEq/hr (range, 11.3 to 41.8); in the 4 patients with suspected recurrence, 9.5 (range, 4.4 to 11.8).The operative technique was changed in one respect; the distal 5 to 7.5 cm of the esophagus was skeletonized. In 14 patients, the mean PAOI-BAO +/- S.E. within 3 months of PGV was 1985 +/- 0.7 mEq/hr, and 13 of 14 values were less than 5 mEq/hr. One patient developed recurrent ulcer and required re-operation; this patient's value for PAO-BAO was 1.8 mEq/hr. The results show quantitatively that great differences in the completeness of PGV result from differences in the periesophageal dissection and emphasize its importance if optimal results are to be obtained and, especially, if the efficacy of the operation is to be judged. PMID:1015889

  7. [The implementation of polymerase chain reaction technique: the real time to reveal and differentiate the viruses of human papilloma of high carcinogenic risk].

    Science.gov (United States)

    Andosova, L D; Kontorshchikova, K N; Blatova, O L; Kudel'kina, S Iu; Kuznetsova, I A; Belov, A V; Baĭkova, R A

    2011-07-01

    The polymerase chain reaction technique was applied in "real time" format to evaluate the occurrence rate and infection ratio of various genotypes of human papilloma of high carcinogenic risk in virus-positive women and contact persons. The examination sampling consisted of 738 women aged of 17-50 years. The examination results permitted to establish high percentage of infection of 546 patients (74%) by carcinogenic papilloma viruses. The analysis of detection rate of various genotypes of human papilloma of high carcinogenic risk established that the 56th and 16th types of high carcinogenic risk are revealed more often than others--in 33% and 15.4% correspondingly. In males, first place in occurrence rate is for those types of virus of human papilloma: the 56th n = 10 (33.3%), 16th n = 3 (10%), 45th n = 3 (10%), 51th n = 3 (10%). The rest of genotypes are detected in 3-7% cases.

  8. In situ NMR and electrochemical quartz crystal microbalance techniques reveal the structure of the electrical double layer in supercapacitors.

    Science.gov (United States)

    Griffin, John M; Forse, Alexander C; Tsai, Wan-Yu; Taberna, Pierre-Louis; Simon, Patrice; Grey, Clare P

    2015-08-01

    Supercapacitors store charge through the electrosorption of ions on microporous electrodes. Despite major efforts to understand this phenomenon, a molecular-level picture of the electrical double layer in working devices is still lacking as few techniques can selectively observe the ionic species at the electrode/electrolyte interface. Here, we use in situ NMR to directly quantify the populations of anionic and cationic species within a working microporous carbon supercapacitor electrode. Our results show that charge storage mechanisms are different for positively and negatively polarized electrodes for the electrolyte tetraethylphosphonium tetrafluoroborate in acetonitrile; for positive polarization charging proceeds by exchange of the cations for anions, whereas for negative polarization, cation adsorption dominates. In situ electrochemical quartz crystal microbalance measurements support the NMR results and indicate that adsorbed ions are only partially solvated. These results provide new molecular-level insight, with the methodology offering exciting possibilities for the study of pore/ion size, desolvation and other effects on charge storage in supercapacitors.

  9. Conjunction Assessment Techniques and Operational Results from the Magnetospheric Multiscale Mission

    Science.gov (United States)

    Williams, Trevor; Carpenter, Russell; Farahmand, Mitra; Ottenstein, Neil; Demoret, Michael; Godine, Dominic

    2017-01-01

    This paper will describe the results that have been obtained to date during the MMS mission concerning conjunction assessment. MMS navigation makes use of a weak-signal GPS-based system: this allows signals to be received even when MMS is flying above the GPS orbits, producing a highly accurate determination of the four MMS orbits. This data is downlinked to the MMS Mission Operations Center (MOC) and used by the Flight Dynamics Operations Area (FDOA) for both maneuver design and conjunction assessment. The MMS fly in tetrahedron formations around apogee, in order to collect simultaneous particles and fields science data. The original plan was to fly tetrahedra between 10 and 160 km in size; however, after Phase 1a of the mission, the science team requested that smaller sizes be flown if feasible. After analysis (to be detailed in a companion paper), a new minimum size of 7 km was decided upon. Flying at this reduced scale size makes conjunction assessment between the MMS spacecraft even more important: the methods that are used by the MMS FDOA to address this problem will be described in the paper, and a summary given of the previous analyses that went into the development of these techniques. Details will also be given of operational experiences to date. Finally, two CA mitigation maneuver types that have been designed (but never yet required to actually be performed) will also be outlined.

  10. Laparoscopic parastomal hernia repair: a description of the technique and initial results.

    Science.gov (United States)

    Zacharakis, Emmanouil; Hettige, Roland; Purkayastha, Sanjay; Aggarwal, Rajesh; Athanasiou, Thanos; Darzi, Ara; Ziprin, Paul

    2008-06-01

    In this study, the authors review their initial results with the laparoscopic approach for parastomal hernia repair. Between 2006 and 2007, 4 patients were treated laparoscopically at our institution. The hernia sac was not excised. A piece of Gore-Tex DualMesh with a central keyhole and a radial incision was cut so that it could provide at least 3 to 5 cm of overlap of the fascial defect. The mesh was secured to the margins of the hernia with circumferential metal tacking and trans-fascial sutures. No complications occurred in the postoperative period. After a median follow-up of 9 months, recurrence occurred in 1 patient. This was our first patient in whom mesh fixation was performed only with circumferential metal tacking. The laparoscopic repair of parastomal hernias seems to be a safe, feasible and promising technique offering the advantages of minimally-invasive surgery. The success of this approach depends on longer follow-up reports and standardization of the technical elements.

  11. INVESTIGATION OF DAMPENED SYSTEM AND DRY OFFSET PRINTING TECHNIQUES AND COMPARISON OF REPRODUCTION RESULTS

    Directory of Open Access Journals (Sweden)

    Sinan ULU

    2006-03-01

    Full Text Available Printing ; is the process of reproduction rapid transfering of the images, inscriptions, figures and graphics on to a surface in the original format. The dampened system offset printing is the smooth printing system. Smooth printing is based on the principal of repelling of the water by the oil inside the ink and not to be mixed with. The printed and unprinted surfaces on the plate has a chemical characteristic. The process of printing occurs in the way that. The unprinted areas captures water and repell ink, the printed areas captures ink and repell water.The dry offset system is; the combination of the flexo and dampened system offset methods. In the method the relief part of the plate transfers the image to the smooth surfaced rubber printing cylinder and the image is transferred to the material by the cylinder. Water is not needed for humidification. So the plate is not wetted before printing. The pictures or positive dias are not printed by dry ofset method but, the hand dravings, very detailed desings and quite small texts could be printed to the range of six colors. In this study, an evaluation of the comparison of the process stages and reproduction results of the two techniques is conducted.

  12. Development of a New Technique to Assess Susceptibility to Predation Resulting from Sublethal Stresses (Indirect Mortality)

    Energy Technology Data Exchange (ETDEWEB)

    Cada, G.F.

    2003-08-25

    Fish that pass through a hydroelectric turbine may not be killed directly, but may nonetheless experience sublethal stresses that will increase their susceptibility to predators (indirect mortality). There is a need to develop reliable tests for indirect mortality so that the full consequences of passage through turbines (and other routes around a hydroelectric dam) can be assessed. We evaluated a new technique for assessing indirect mortality, based on a behavioral response to a startling stimulus (akin to perceiving an approaching predator). We compare this technique to the standard predator preference test. The behavioral response is a rapid movement commonly referred to as a startle response, escape response, or C-shape, based on the characteristic body position assumed by the fish. When viewed from above, a startled fish bends into a C-shape, then springs back and swims away in a direction different from its original orientation. This predator avoidance (escape) behavior can be compromised by sublethal stresses that temporarily stun or disorient the fish. We subjected striped shiners and fathead minnows to varying intensities of either turbulence (10-, 20- or 30-min) or 2-min exposures to a fish anesthetic (100 or 200 mg/L of tricaine methanesulfonate), and evaluated their subsequent behavior. Individual fish were given a startle stimulus and filmed with a high-speed video camera. Each fish was startled and filmed twice before being stressed, and then at 1-, 5-, 15-, and 30-min post-exposure. The resulting image files were analyzed for a variety of behavioral measures including: presence of a response, time to first reaction, duration of reaction, time to formation of maximum C-shape, time to completion of C-shape, and completeness of C-shape. The most immediate measure of potential changes in fish behavior was whether stressed fish exhibited a startle response. For striped shiners, the number of fish not responding to the stimulus was significantly different

  13. Evaluation of Midterm Clinical Results of All inside Suture Technique in Meniscus Repair

    Directory of Open Access Journals (Sweden)

    Murat Gül

    2015-03-01

    Full Text Available Aim: The aim of this study was to evaluate the functional outcomes of arthroscopic all-inside meniscal repair at an average 5-year follow-up. Methods: Thirty-two patients (29 males 3 females; 19 right knees, 13 left knees, who underwent arthroscopic all-inside meniscal repair, were included in the study. Clinical examination and magnetic resonance imaging were the main diagnostic tools. The mean age of the patients was 28 years (23-41 years. ACL reconstruction was performed in the same session in 12 patients with meniscal injury associated with ACL tear. Preoperative and postoperative functional knee scores of the patients were assessed by modified Marshall functional knee scores in their last follow-up. Results: The mean follow-up period was 58 months (range 49- 81. Marshall knee scores in the last follow-up were found to be excellent in 23 patients, good - in 8 patients, and moderate in 1 patient. ACL reconstruction was performed in the same session in 12 patients with meniscal injury associated with ACL tear. A statistically significant functional improvement was detected in patients with meniscal repair after 5 years. Conclusion: This study showed that all-inside meniscal repair technique is an easy and reliable method for the treatment of meniscus tears. (The Medical Bulletin of Haseki 2015; 53:47-51

  14. The 21-SPONGE HI Absorption Survey I: Techniques and Initial Results

    CERN Document Server

    Murray, Claire E; Goss, W M; Dickey, John M; Heiles, Carl; Lindner, Robert R; Babler, Brian; Pingel, Nickolas M; Lawrence, Allen; Jencson, Jacob; Hennebelle, Patrick

    2015-01-01

    We present methods and results from "21-cm Spectral Line Observations of Neutral Gas with the EVLA" (21-SPONGE), a large survey for Galactic neutral hydrogen (HI) absorption with the Karl G. Jansky Very Large Array (VLA). With the upgraded capabilities of the VLA, we reach median root-mean-square (RMS) noise in optical depth of $\\sigma_{\\tau}=9\\times 10^{-4}$ per $0.42\\rm\\,km\\,s^{-1}$ channel for the 31 sources presented here. Upon completion, 21-SPONGE will be the largest HI absorption survey with this high sensitivity. We discuss the observations and data reduction strategies, as well as line fitting techniques. We prove that the VLA bandpass is stable enough to detect broad, shallow lines associated with warm HI, and show that bandpass observations can be combined in time to reduce spectral noise. In combination with matching HI emission profiles from the Arecibo Observatory ($\\sim3.5'$ angular resolution), we estimate excitation (or spin) temperatures ($\\rm T_s$) and column densities for Gaussian componen...

  15. Thermodynamic Spectrum of Solar Flares Based on SDO/EVE Observations: Techniques and First Results

    CERN Document Server

    Wang, Yuming; Zhang, Jie; Liu, Kai; Liu, Rui; Shen, Chenglong; Chamberlin, Phillip C

    2015-01-01

    SDO/EVE provide rich information of the thermodynamic processes of solar activities, particularly of solar flares. Here, we develop a method to construct thermodynamic spectrum (TDS) charts based on the EVE spectral lines. Reading from the charts, we are able to easily recognize if there is a late phase following a main phase of a flare, and able to learn the begin, peak and end times of the flare as well as the drift of the temperature, i.e., the cooling rate, of the heated plasma during the flare. Through four M-class flares of different types, we illustrate which thermodynamic information can be revealed from the TDS charts. Further, we investigate the TDS charts of all the flares greater than M5.0, and some interesting results are achieved. First, there are two distinct drift patterns, called Type I and Type II. For Type I flares, the enhanced emission drifts from high to low temperture, whereas for Type II flares, the drift is somewhat reversed, suggesting a more violent and durable heating during Type I...

  16. Early Results of Chimney Technique for Type B Aortic Dissections Extending to the Aortic Arch

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Chen [Affiliated Hospital of Nantong University, Department of General Surgery (China); Tang, Hanfei; Qiao, Tong; Liu, Changjian; Zhou, Min, E-mail: 813477618@qq.com [The Affiliated Hospital of Nanjing University Medical School, Department of Vascular Surgery, Nanjing Drum Tower Hospital (China)

    2016-01-15

    ObjectiveTo summarize our early experience gained from the chimney technique for type B aortic dissection (TBAD) extending to the aortic arch and to evaluate the aortic remodeling in the follow-up period.MethodsFrom September 2011 to July 2014, 27 consecutive TBAD patients without adequate proximal landing zones were retrograde analyzed. Chimney stent-grafts were deployed parallel to the main endografts to reserve flow to branch vessels while extending the landing zones. In the follow-up period, aortic remodeling was observed with computed tomography angiography.ResultsThe technical success rate was 100 %, and endografts were deployed in zone 0 (n = 3, 11.1 %), zone 1 (n = 18, 66.7 %), and zone 2 (n = 6, 22.2 %). Immediately, proximal endoleaks were detected in 5 patients (18.5 %). During a mean follow-up period of 17.6 months, computed tomography angiography showed all the aortic stent-grafts and chimney grafts to be patent. Favorable remodeling was observed at the level of maximum descending aorta and left subclavian artery with expansion of true lumen (from 18.4 ± 4.8 to 25 ± 0.86 mm, p < 0.001 and 27.1 ± 0.62 to 28.5 ± 0.37 mm, p < 0.001) and depressurization of false lumen (from 23.7 ± 2.7 to 8.7 ± 3.8 mm, p < 0.001, from 5.3 ± 1.2 to 2.1 ± 2.1 mm, p < 0.001). While at the level of maximum abdominal aorta, suboptimal remodeling of the total aorta (from 24.1 ± 0.4 to 23.6 ± 1.5 mm, p = 0.06) and true lumen (from 13.8 ± 0.6 to 14.5 ± 0.4 mm, p = 0.08) was observed.ConclusionBased on our limited experience, the chimney technique with thoracic endovascular repair is demonstrated to be promising for TBAD extending to the arch with favorable aortic remodeling.

  17. Nurse Practitioners' Use of Communication Techniques: Results of a Maryland Oral Health Literacy Survey.

    Directory of Open Access Journals (Sweden)

    Laura W Koo

    Full Text Available We examined nurse practitioners' use and opinions of recommended communication techniques for the promotion of oral health as part of a Maryland state-wide oral health literacy assessment. Use of recommended health-literate and patient-centered communication techniques have demonstrated improved health outcomes.A 27-item self-report survey, containing 17 communication technique items, across 5 domains, was mailed to 1,410 licensed nurse practitioners (NPs in Maryland in 2010. Use of communication techniques and opinions about their effectiveness were analyzed using descriptive statistics. General linear models explored provider and practice characteristics to predict differences in the total number and the mean number of communication techniques routinely used in a week.More than 80% of NPs (N = 194 routinely used 3 of the 7 basic communication techniques: simple language, limiting teaching to 2-3 concepts, and speaking slowly. More than 75% of respondents believed that 6 of the 7 basic communication techniques are effective. Sociodemographic provider characteristics and practice characteristics were not significant predictors of the mean number or the total number of communication techniques routinely used by NPs in a week. Potential predictors for using more of the 7 basic communication techniques, demonstrating significance in one general linear model each, were: assessing the office for user-friendliness and ever taking a communication course in addition to nursing school.NPs in Maryland self-reported routinely using some recommended health-literate communication techniques, with belief in their effectiveness. Our findings suggest that NPs who had assessed the office for patient-friendliness or who had taken a communication course beyond their initial education may be predictors for using more of the 7 basic communication techniques. These self-reported findings should be validated with observational studies. Graduate and continuing

  18. Percutaneous elastic intramedullary nailing of metacarpal fractures: Surgical technique and clinical results study

    Directory of Open Access Journals (Sweden)

    Farook Mohamed Z

    2011-07-01

    Full Text Available Abstract Background We reviewed our results and complications of using a pre-bent 1.6 mm Kirschner wire (K-wire for extra-articular metacarpal fractures. The surgical procedure was indicated for angulation at the fracture site in a true lateral radiograph of at least 30 degrees and/or in the presence of a rotatory deformity. Methods A single K-wire is pre-bent in a lazy-S fashion with a sharp bend at approximately 5 millimeters and a longer smooth curve bent in the opposite direction. An initial entry point is made at the base of the metacarpal using a 2.5 mm drill by hand. The K-wire is inserted blunt end first in an antegrade manner and the fracture reduced as the wire is passed across the fracture site. With the wire acting as three-point fixation, early mobilisation is commenced at the metacarpo-phalangeal joint in a Futuro hand splint. The wire is usually removed with pliers post-operatively at four weeks in the fracture clinic. Results We studied internal fixation of 18 little finger and 2 ring finger metacarpal fractures from November 2007 to August 2009. The average age of the cohort was 25 years with 3 women and 17 men. The predominant mechanism was a punch injury with 5 diaphyseal and 15 metacarpal neck fractures. The time to surgical intervention was a mean 13 days (range 4 to 28 days. All fractures proceeded to bony union. The wire was extracted at an average of 4.4 weeks (range three to six weeks. At an average follow up of 8 weeks, one fracture had to be revised for failed fixation and three superficial wound infections needed antibiotic treatment. Conclusions With this simple and minimally invasive technique performed as day-case surgery, all patients were able to start mobilisation immediately. The general outcome was good hand function with few complications.

  19. Longo's痔切除術%Stapled Haemorrhoidectomy with Longo's Technique: Our Results After Three Years

    Institute of Scientific and Technical Information of China (English)

    David BERNASCONI; Arianna C. SANZO; Giacomo URSO; Giovanni PIAZZA; Nello GRASSI; Alfonso M. MAIORANA

    2001-01-01

    The authors evaluate a new surgical procedure for the treatment of haemorrhoids. The technique was introduced by Longo in 1994 and consists in what is defined "Anal Lifting". With the help of a special kit equipped of a stapler. The surgical procedure gives several advantages, particularly in the post-operative treatment.No need of medications and no post-operative pain, the technique is also suitable for day-surgery regimen. The authors focuse the need of further long term evaluation.

  20. A comparison of two common sample preparation techniques for lipid and fatty acid analysis in three different coral morphotypes reveals quantitative and qualitative differences.

    Science.gov (United States)

    Conlan, Jessica A; Rocker, Melissa M; Francis, David S

    2017-01-01

    Lipids are involved in a host of biochemical and physiological processes in corals. Therefore, changes in lipid composition reflect changes in the ecology, nutrition, and health of corals. As such, accurate lipid extraction, quantification, and identification is critical to obtain comprehensive insight into a coral's condition. However, discrepancies exist in sample preparation methodology globally, and it is currently unknown whether these techniques generate analogous results. This study compared the two most common sample preparation techniques for lipid analysis in corals: (1) tissue isolation by air-spraying and (2) crushing the coral in toto. Samples derived from each preparation technique were subsequently analysed to quantify lipids and their constituent classes and fatty acids in four common, scleractinian coral species representing three distinct morphotypes (Acropora millepora, Montipora crassotuberculata, Porites cylindrica, and Pocillopora damicornis). Results revealed substantial amounts of organic material, including lipids, retained in the skeletons of all species following air-spraying, causing a marked underestimation of total lipid concentration using this method. Moreover, lipid class and fatty acid compositions between the denuded skeleton and sprayed tissue were substantially different. In particular, the majority of the total triacylglycerol and total fatty acid concentrations were retained in the skeleton (55-69% and 56-64%, respectively). As such, the isolated, sprayed tissue cannot serve as a reliable proxy for lipid quantification or identification in the coral holobiont. The in toto crushing method is therefore recommended for coral sample preparation prior to lipid analysis to capture the lipid profile of the entire holobiont, permitting accurate diagnoses of coral condition.

  1. New results and implications for lunar crustal iron distribution using sensor data fusion techniques

    Science.gov (United States)

    Clark, P. E.; McFadden, L. A.

    2000-02-01

    Remote measurements of the Moon have provided iron maps, and thus essential constraints for models of lunar crustal formation and mare basalt petrogenesis. A bulk crustal iron map was produced for the equatorial region from Apollo gamma-ray (AGR) spectrometer measurements, and a global iron variation map from recent Clementine spectral reflectance (CSR) measurements. Both iron maps show bimodal distribution, but have significantly different peak values and variations. In this paper, CSR data have been recalibrated to pyroxene in lunar landing site soils. A residual iron map is derived from the difference between AGR (bulk) and recalibrated CSR (pyroxene) iron abundances. The most likely interpretation is that the residual represents ferrous iron in olivine. This residual iron is anticorrelated to basin age, with older basins containing less olivine, suggesting segregation of basin basalt sources from a progressively fractionating underlying source region at the time of basin formation. Results presented here provide a quantitative basis for (1) establishing the relationship between direct geochemical (gamma-ray, X-ray) and mineralogical (near-IR) remote sensing data sets using sensor data fusion techniques to allow (2) simultaneous determination of elemental and mineralogical component distribution on remote targets and (3) meaningful interpretation of orbital and ground-based spectral reflectance measurements. When calibrated data from the Lunar Prospector mission are available, mapping of bulk crustal iron and iron-bearing soil components will be possible for the entire Moon. Similar analyses for data from the Near Earth Asteroid Rendezvous (NEAR) mission to asteroid 433 Eros will constrain models of asteroid formation.

  2. Results of a nuclear power plant application of A New Technique for Human Error Analysis (ATHEANA)

    Energy Technology Data Exchange (ETDEWEB)

    Whitehead, D.W.; Forester, J.A. [Sandia National Labs., Albuquerque, NM (United States); Bley, D.C. [Buttonwood Consulting, Inc. (United States)] [and others

    1998-03-01

    A new method to analyze human errors has been demonstrated at a pressurized water reactor (PWR) nuclear power plant. This was the first application of the new method referred to as A Technique for Human Error Analysis (ATHEANA). The main goals of the demonstration were to test the ATHEANA process as described in the frame-of-reference manual and the implementation guideline, test a training package developed for the method, test the hypothesis that plant operators and trainers have significant insight into the error-forcing-contexts (EFCs) that can make unsafe actions (UAs) more likely, and to identify ways to improve the method and its documentation. A set of criteria to evaluate the success of the ATHEANA method as used in the demonstration was identified. A human reliability analysis (HRA) team was formed that consisted of an expert in probabilistic risk assessment (PRA) with some background in HRA (not ATHEANA) and four personnel from the nuclear power plant. Personnel from the plant included two individuals from their PRA staff and two individuals from their training staff. Both individuals from training are currently licensed operators and one of them was a senior reactor operator on shift until a few months before the demonstration. The demonstration was conducted over a 5-month period and was observed by members of the Nuclear Regulatory Commission`s ATHEANA development team, who also served as consultants to the HRA team when necessary. Example results of the demonstration to date, including identified human failure events (HFEs), UAs, and EFCs are discussed. Also addressed is how simulator exercises are used in the ATHEANA demonstration project.

  3. The Oblique Metaphyseal Shortening Osteotomy of the Distal Ulna: Surgical Technique and Results of Ten Patients.

    Science.gov (United States)

    Benis, Szabolcs; Goubau, Jean F; Mermuys, Koen; Van Hoonacker, Petrus; Berghs, Bart; Kerckhove, Diederick; Vanmierlo, Bert

    2017-02-01

    Background Ulnocarpal abutment is a common condition following distal radius fractures. There are different surgical methods of treatment for this pathology: open and arthroscopic wafer procedure or an ulnar shortening osteotomy. We describe an oblique metaphyseal shortening osteotomy of the distal ulna using two cannulated headless compression screws. We report the results of 10 patients treated with this method. Materials and Methods Out of 17 patients, 10 could be reviewed retrospectively for this study. Patient-rated outcomes were measured using the VAS (visual analogue scale) for pain, PRWHE (patient-rated wrist and hand evaluation) survey, and Quick-DASH (disability of arm, shoulder and hand) survey for functional outcomes. At the review we measured the range of motion (ROM) of the wrist (extension and flexion, ulnar and radial deviation, pronation and supination). Grip strength, pronation, and supination strength of the forearm was measured using a calibrated hydraulic dynamometer. ROM and strength of the affected wrist was compared with ROM and strength of the unaffected wrist. Surgical Procedure Oblique long metaphyseal osteotomy of the distal ulna (from proximal-ulnar to distal-radial), fixed with two cannulated headless compression screws. Results The average postoperative VAS score for pain was 23.71 (standard deviation [SD] of 30.41). The average postoperative PRWHE score was 32.55 (SD of 26.28). The average postoperative Quick-DASH score was 28.65 (SD of 27.21). The majority of patients had a comparable ROM and strength between the operated side and the non-operated side. Conclusion This surgical technique has the advantage of reducing the amount of hardware and to decrease the potential hinder caused by it on medium term. Moreover, the incision remains smaller, and the anatomic metaphyseal localization of the osteotomy potentially allows a better and rapid healing.

  4. Triple labrum tears repaired with the JuggerKnot™ soft anchor: Technique and results

    Directory of Open Access Journals (Sweden)

    Vivek Agrawal

    2015-01-01

    Full Text Available Purpose: The 2-year outcomes of patients undergoing repair of triple labrum tears using an all-suture anchor device were assessed. Materials and Methods: Eighteen patients (17 male, one female; mean age 36.4 years, range: 14.2-62.3 years with triple labrum tears underwent arthroscopic repair using the 1.4 mm JuggerKnot Soft Anchor (mean number of anchors 11.5, range: 9-19 anchors. Five patients had prior surgeries performed on their operative shoulder. Patients were followed for a mean of 2.0 years (range: 1.6-3.0 years. Constant-Murley shoulder score (CS and Flexilevel scale of shoulder function (FLEX-SF scores were measured, with preoperative and final postoperative mean scores compared with a paired Student′s t-test (P < 0.05. Magnetic resonance imaging (MRI was also performed at final postoperative. Results: Overall total CS and FLEX-SF scores increased from 52.9 ± 20.4 to 84.3 ± 10.7 (P < 0.0001 and from 29.3 ± 4.7 to 42.0 ± 7.3 (P < 0.0001, respectively. When divided into two groups by whether or not glenohumeral arthrosis was present at the time of surgery (n = 9 each group, significant improvements in CS and FLEX-SF were obtained for both groups (P < 0.0015. There were no intraoperative complications. All patients, including contact athletes, returned to their preinjury level of sports activity and were satisfied. MRI evaluation revealed no instances of subchondral cyst formation or tunnel expansion. Anchor tracts appeared to heal with fibrous tissue, complete bony healing, or combined fibro-osseous healing. Conclusion: Our results are encouraging, demonstrating a consistent healing of the anchor tunnels through arthroscopic treatment of complex labrum lesions with a completely suture-based implant. It further demonstrates a meaningful improvement in patient outcomes, a predictable return to activity, and a high rate of patient satisfaction. Level of Evidence: Level IV case series.

  5. Measuring Three-Dimensional Thorax Motion Via Biplane Radiographic Imaging: Technique and Preliminary Results.

    Science.gov (United States)

    Baumer, Timothy G; Giles, Joshua W; Drake, Anne; Zauel, Roger; Bey, Michael J

    2016-01-01

    Measures of scapulothoracic motion are dependent on accurate imaging of the scapula and thorax. Advanced radiographic techniques can provide accurate measures of scapular motion, but the limited 3D imaging volume of these techniques often precludes measurement of thorax motion. To overcome this, a thorax coordinate system was defined based on the position of rib pairs and then compared to a conventional sternum/spine-based thorax coordinate system. Alignment of the rib-based coordinate system was dependent on the rib pairs used, with the rib3:rib4 pairing aligned to within 4.4 ± 2.1 deg of the conventional thorax coordinate system.

  6. Fast Spectral Velocity Estimation Using Adaptive Techniques: In-Vivo Results

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jakobsson, Andreas; Udesen, Jesper

    2007-01-01

    spectral Capon (BPC) method is based on a standard minimum variance technique adapted to account for both averaging over slowtime and depth. The Blood Amplitude and Phase Estimation technique (BAPES) is based on finding a set of matched filters (one for each velocity component of interest) and filtering...... the blood process over slow-time and averaging over depth to find the power spectral density estimate. In this paper, the two adaptive methods are explained, and performance Is assessed in controlled steady How experiments and in-vivo measurements. The three methods were tested on a circulating How rig...

  7. Results and analysis of the 2008-2009 Insulin Injection Technique Questionnaire survey

    NARCIS (Netherlands)

    De Coninck, Carina; Frid, Anders; Gaspar, Ruth; Hicks, Debbie; Hirsch, Larry; Kreugel, Gillian; Liersch, Jutta; Letondeur, Corinne; Sauvanet, Jean-Pierre; Tubiana, Nadia; Strauss, Kenneth

    2010-01-01

    Background: The efficacy of injection therapy in diabetes depends on correct injection technique and, to provide patients with guidance in this area, we must understand how they currently inject. Methods: From September 2008 to June 2009, 4352 insulin-injecting Type 1 and Type 2 diabetic patients fr

  8. Separator Reconnection at the Magnetopause for Predominantly Northward and Southward IMF: Techniques and Results

    Science.gov (United States)

    Glocer, Alex; Dorelli, J.; Toth, G.; Komar, C. M.; Cassak, P. A.

    2016-01-01

    In this work, we demonstrate how to track magnetic separators in three-dimensional simulated magnetic fields with or without magnetic nulls, apply these techniques to enhance our understanding of reconnection at the magnetopause. We present three methods for locating magnetic separators and apply them to 3-D resistive MHD simulations of the Earth's magnetosphere using the Block-Adaptive-Tree Solar-wind Roe-type Upwind Scheme code. The techniques for finding separators and determining the reconnection rate are insensitive to interplanetary magnetic field (IMF) clock angle and can in principle be applied to any magnetospheric model. Moreover, the techniques have a number of advantages over prior separator finding techniques applied to the magnetosphere. The present work examines cases of high and low resistivity for two clock angles. We go beyond previous work examine the separator during Flux Transfer Events (FTEs). Our analysis of reconnection on the magnetopause yields a number of interesting conclusions: Reconnection occurs all along the separator even during predominately northward IMF cases. Multiple separators form in low-resistivity conditions, and in the region of an FTE the separator splits into distinct branches. Moreover, the local contribution to the reconnection rate, as determined by the local parallel electric field, drops in the vicinity of the FTE with respect to the value when there are none.

  9. Entire papilla preservation technique in the regenerative treatment of deep intrabony defects: 1-Year results.

    Science.gov (United States)

    Aslan, Serhat; Buduneli, Nurcan; Cortellini, Pierpaolo

    2017-09-01

    This study evaluates the clinical outcomes of a novel tunnel-like surgical technique in the treatment of isolated deep intrabony defects. Twelve patients presenting with at least one isolated deep intrabony defect received regenerative periodontal treatment with "entire papilla preservation (EPP)" technique. Access to the intrabony defect for debridement was provided by a bevelled vertical releasing incision positioned in the buccal gingiva of the neighbouring inter-dental space. Following the elevation of a buccal flap, an inter-dental tunnel was prepared undermining the defect-associated papilla. Granulation tissue was removed, root surfaces were carefully debrided and bone substitutes and enamel matrix derivative were applied. Microsurgical suturing technique was used for optimal wound closure. Early healing was uneventful in all cases, and 100% wound closure was maintained during the entire healing period. At 1-year, there was significant attachment gain of 6.83±2.51 mm (p<0.001). The 7±2.8 mm reduction in probing depth was also significant (p<0.001), which was associated with minimal increase in gingival recession (0.16±0.38 mm, p=0.166). Tunnel-like "EPP" technique may limit the risk of wound failure particularly in the early healing phase, thereby preventing exposure of regenerative biomaterials, possibly enhancing stabilization of blood clot in deep intrabony defects and leading to optimal clinical outcomes. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. The results of cataract nigra cases operated with the mini-nuc technique.

    Science.gov (United States)

    Yuzbasioglu, Erdal; Helvacioglu, Firat; Tugcu, Betul; Terzi, Nazire; Keskinbora, Kadircan

    2009-12-01

    The purpose of this study was to evaluate the efficacy and safety of the mini-nuc technique for the removal of brunescent and black cataracts. A prospective study was carried out in 33 eyes of 33 patients with cataract nigra operated with the mini-nuc technique between April 2002 and June 2003. Slit-lamp examinations, intraocular pressure (IOP) measurements, and best-corrected visual acuity (BCVA) were assessed pre- and postoperatively. Accompanying systemic diseases were noted. Intraoperative and postoperative complications were evaluated. Unilateral eyes of 33 patients (18 male [54.5%], 15 female [45.5%]) aged between 65 and 90 years (mean 72 years) were operated with the mini-nuc technique. Preoperative BCVA values varied between light perception and 0.2 in the Snellen chart. Intraocular lenses (IOL) were implanted into all of the patients (27 in-the-bag [81.8%], four to sulcus [12.1%], and two with scleral fixation [6.1%]). During the surgery, five patients (15.15%) had zonular dialysis and two (6.1%) had posterior capsule rupture and vitreous loss. Postoperatively, three (9.1%) rises in IOP, two (6.1%) hyphema, and one (3%) IOL subluxation were observed. At the first day visit, the mean of the uncorrected visual acuities (UCVA) was 0.5 in the Snellen chart. At the third month visit, the mean BCVA was observed to be 0.8. The residual mean astigmatism was 0.75 D against the rule. The mini-nuc technique was effective in removing brunescent and black cataracts with a low rate of serious complications. The mini-nuc technique, which is also performed with a small incision and without sutures, might be an alternative to phacoemulsification in cases of cataract nigra.

  11. Salivary bacterial fingerprints of established oral disease revealed by the Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS technique

    Directory of Open Access Journals (Sweden)

    Daniel Belstrøm

    2016-01-01

    Full Text Available Background and objective: The composition of the salivary microbiota, as determined using various molecular methods, has been reported to differentiate oral health from diseases. Thus, the purpose of this study was to utilize the newly developed molecular technique HOMINGS (Human Oral Microbe Identification using Next Generation Sequencing for comparison of the salivary microbiota in patients with periodontitis, patients with dental caries, and orally healthy individuals. The hypothesis was that this method could add on to the existing knowledge on salivary bacterial profiles in oral health and disease. Design: Stimulated saliva samples (n=30 were collected from 10 patients with untreated periodontitis, 10 patients with untreated dental caries, and 10 orally healthy individuals. Salivary microbiota was analyzed using HOMINGS and statistical analysis was performed using Kruskal–Wallis test with Benjamini–Hochberg's correction. Results: From a total of 30 saliva samples, a mean number of probe targets of 205 (range 120–353 were identified, and a statistically significant higher mean number of targets was registered in samples from patients with periodontitis (mean 220, range 143–306 and dental caries (mean 221, range 165–353 as compared to orally healthy individuals (mean 174, range 120–260 (p=0.04 and p=0.04. Nine probe targets were identified with a different relative abundance between groups (p<0.05. Conclusions: Cross-sectional comparison of salivary bacterial profiles by means of HOMINGS analysis showed that different salivary bacterial profiles were associated with oral health and disease. Future large-scale prospective studies are needed to evaluate if saliva-based screening for disease-associated oral bacterial profiles may be used for identification of patients at risk of acquiring periodontitis and dental caries.

  12. Colonic perforation resulting from ingested chicken bone revealing previously undiagnosed colonic adenocarcinoma: report of a case and review of literature.

    Science.gov (United States)

    McGregor, Douglas H; Liu, Xiaoying; Ulusarac, Ozlem; Ponnuru, Kimberly D; Schnepp, Stephanie L

    2011-02-18

    An 86 year old male with a four-day history of nonspecific gastrointestinal symptoms was found on colonoscopy to have evidence of sigmoid colon obstruction and possible perforation. Emergent operative exploration revealed diffuse peritonitis, sigmoid perforation, adjacent dense adhesions, and a foreign body protruding through the perforated area. Pathologic examination showed the foreign body to be a sliver of bone consistent with chicken bone and the sigmoid subacute perforation to be associated distally with a circumferential ulcerated obstructing mass, microscopically seen to be transmurally infiltrating adenocarcinoma, signet-ring cell type. There was extensive acute and organizing peritonitis, 100% Escherichia coli was cultured from peritoneal fluid, and the patient died two days postoperatively with sepsis and hypotension. This appears to be the fifth reported case of colonic perforation resulting from foreign body perforation due to previously undiagnosed adenocarcinoma. The four previously reported cases were all deeply invasive adenocarcinoma of sigmoid colon, and the foreign bodies included three chicken/poultry bones and a metallic staple. These five cases are highly unusual examples of a potentially lethal malignant neoplasm being clinically revealed by a usually (but not always) innocuous event, the ingestion of a small foreign body.

  13. Colonic perforation resulting from ingested chicken bone revealing previously undiagnosed colonic adenocarcinoma: report of a case and review of literature

    Directory of Open Access Journals (Sweden)

    Ulusarac Ozlem

    2011-02-01

    Full Text Available Abstract An 86 year old male with a four-day history of nonspecific gastrointestinal symptoms was found on colonoscopy to have evidence of sigmoid colon obstruction and possible perforation. Emergent operative exploration revealed diffuse peritonitis, sigmoid perforation, adjacent dense adhesions, and a foreign body protruding through the perforated area. Pathologic examination showed the foreign body to be a sliver of bone consistent with chicken bone and the sigmoid subacute perforation to be associated distally with a circumferential ulcerated obstructing mass, microscopically seen to be transmurally infiltrating adenocarcinoma, signet-ring cell type. There was extensive acute and organizing peritonitis, 100% Escherichia coli was cultured from peritoneal fluid, and the patient died two days postoperatively with sepsis and hypotension. This appears to be the fifth reported case of colonic perforation resulting from foreign body perforation due to previously undiagnosed adenocarcinoma. The four previously reported cases were all deeply invasive adenocarcinoma of sigmoid colon, and the foreign bodies included three chicken/poultry bones and a metallic staple. These five cases are highly unusual examples of a potentially lethal malignant neoplasm being clinically revealed by a usually (but not always innocuous event, the ingestion of a small foreign body.

  14. Planned posterior assisted levitation in severe subluxated cataract: Surgical technique and clinical results

    Directory of Open Access Journals (Sweden)

    Tova Lifshitz

    2012-01-01

    Full Text Available We report the surgical technique and outcome of planned posterior assisted levitation (P-PAL in four cases of subluxated cataract. P-PAL was planned as the preferred approach in all cases. A spatula was inserted via the pars plana, the whole lens was lifted to the anterior chamber and then removed through a scleral tunnel incision. Anterior chamber intraocular lenses were implanted in all cases. All four eyes had severe subluxation of the crystalline lenses with marked phacodonesis. Two eyes had history of blunt trauma, and the other two eyes had severe pseudoexfoliation with spontaneous lens subluxation. Follow-up ranged from 1 to 2 years in three cases. The postoperative visual acuity was 20/80 or better. No intraoperative complications were observed. In conclusion, the P-PAL technique was successfully performed during cataract surgery in four eyes with severe subluxated cataracts. There were no complications over the long-term follow-up.

  15. Planned posterior assisted levitation in severe subluxated cataract: Surgical technique and clinical results

    Science.gov (United States)

    Lifshitz, Tova; Levy, Jaime; Kratz, Assaf; Belfair, Nadav; Tsumi, Erez

    2012-01-01

    We report the surgical technique and outcome of planned posterior assisted levitation (P-PAL) in four cases of subluxated cataract. P-PAL was planned as the preferred approach in all cases. A spatula was inserted via the pars plana, the whole lens was lifted to the anterior chamber and then removed through a scleral tunnel incision. Anterior chamber intraocular lenses were implanted in all cases. All four eyes had severe subluxation of the crystalline lenses with marked phacodonesis. Two eyes had history of blunt trauma, and the other two eyes had severe pseudoexfoliation with spontaneous lens subluxation. Follow-up ranged from 1 to 2 years in three cases. The postoperative visual acuity was 20/80 or better. No intraoperative complications were observed. In conclusion, the P-PAL technique was successfully performed during cataract surgery in four eyes with severe subluxated cataracts. There were no complications over the long-term follow-up. PMID:23202402

  16. A truly knotless technique for scleral fixation of intraocular lenses: Two-year results

    Directory of Open Access Journals (Sweden)

    Naresh K Yadav

    2012-01-01

    Full Text Available Scleral fixated intraocular lens (SFIOL is a safe and effective option for managing optical aphakia. Suture related complications like suture erosion, suture breakage, endophthalmitis, etc. are unique to SFIOL. The knots can be covered by partial thickness flaps or they can be rotated into scleral tissues without flaps to reduce the complications. We performed a recently described novel technique which obviates the need for knot and scleral flaps in securing the SFIOL. This novel 2-point Ab externo knotless technique may reduce the knot related problems. Twenty-three eyes undergoing this knotless SFIOL procedure were analyzed for intraoperative and postoperative complications. Twenty-two eyes either maintained or improved on their preoperative vision. All patients had a minimum follow-up of 24 months.

  17. Galaxy Cluster Mass Reconstruction Project: I. Methods and first results on galaxy-based techniques

    CERN Document Server

    Old, L; Pearce, F R; Croton, D; Muldrew, S I; Muñoz-Cuartas, J C; Gifford, D; Gray, M E; von der Linden, A; Mamon, G A; Merrifield, M R; Müller, V; Pearson, R J; Ponman, T J; Saro, A; Sepp, T; Sifón, C; Tempel, E; Tundo, E; Wang, Y O; Wojtak, R

    2014-01-01

    This paper is the first in a series in which we perform an extensive comparison of various galaxy-based cluster mass estimation techniques that utilise the positions, velocities and colours of galaxies. Our primary aim is to test the performance of these cluster mass estimation techniques on a diverse set of models that will increase in complexity. We begin by providing participating methods with data from a simple model that delivers idealised clusters, enabling us to quantify the underlying scatter intrinsic to these mass estimation techniques. The mock catalogue is based on a Halo Occupation Distribution (HOD) model that assumes spherical Navarro, Frenk and White (NFW) haloes truncated at R_200, with no substructure nor colour segregation, and with isotropic, isothermal Maxwellian velocities. We find that, above 10^14 M_solar, recovered cluster masses are correlated with the true underlying cluster mass with an intrinsic scatter of typically a factor of two. Below 10^14 M_solar, the scatter rises as the nu...

  18. Pyrosequencing and mid-infrared spectroscopy techniques reveal distinct aggregate stratification of soil bacterial communities and organic matter composition

    Science.gov (United States)

    This study integrated physical, chemical, and molecular techniques to assess relationships between soil bacterial community structures and the quantity and quality of soil organic carbon (SOC) at the soil microenvironment scale (e.g., within different aggregate size-fractions). To accomplish this g...

  19. Analysis of polyethylene wear of reverse shoulder components: A validated technique and initial clinical results.

    Science.gov (United States)

    Lewicki, Kathleen A; Bell, John-Erik; Van Citters, Douglas W

    2016-06-27

    One of the most prevalent phenomena associated with reverse total shoulder arthroplasty (rTSA) is scapular notching. Current methods examine only the damage to the scapula and no methods are available for quantifying the total wear volume of the polyethylene humeral bearing. Quantifying the polyethylene material loss may provide insight into the mechanism for scapular notching and into the particle dose delivered to the patient. A coordinate measurement machine (CMM) and custom computer algorithms were employed to quantify the volumetric wear of polyethylene humeral bearings. This technique was validated using two never-implanted polyethylene humeral liners with a controlled amount of wear in clinically relevant locations. The technique was determined to be accurate to within 10% of the known value and within 5 mm(3) of the gravimetrically determined values. Following validation, ten retrieved polyethylene humeral liners were analyzed to determine a baseline for future clinical tests. Four of the ten polyethylene humeral liners showed visible and measureable wear volumes ranging from 40 mm(3) to 90 mm(3) total with a maximum wear rate as high as 470 mm(3) /year in one short duration and significantly damaged humeral liner. This validated technique has the potential to relate patient outcomes such as scapular notching grades to polyethylene release into the body. While the total wear volumes are less than reported in literature for cases of osteolysis in knee and hip patients, dosages are well within the osteolytic thresholds that have been suggested, indicating that osteolysis may be a clinical concern in the shoulder. This work provides the basis for future studies that relate volumetric wear to patient outcomes. This article is protected by copyright. All rights reserved.

  20. Mechanics of the ankle and subtalar joints revealed through a 3D quasi-static stress MRI technique.

    Science.gov (United States)

    Siegler, S; Udupa, J K; Ringleb, S I; Imhauser, C W; Hirsch, B E; Odhner, D; Saha, P K; Okereke, E; Roach, N

    2005-03-01

    A technique to study the three-dimensional (3D) mechanical characteristics of the ankle and of the subtalar joints in vivo and in vitro is described. The technique uses an MR scanner compatible 3D positioning and loading linkage to load the hindfoot with precise loads while the foot is being scanned. 3D image processing algorithms are used to derive from the acquired MR images bone morphology, hindfoot architecture, and joint kinematics. The technique was employed to study these properties both in vitro and in vivo. The ankle and subtler joint motion and the changes in architecture produced in response to an inversion load and an anterior drawer load were evaluated. The technique was shown to provide reliable measures of bone morphology. The left-to-right variations in bone morphology were less than 5%. The left-to-right variations in unloaded hindfoot architecture parameters were less than 10%, and these properties were only slightly affected by inversion and anterior drawer loads. Inversion and anterior drawer loads produced motion both at the ankle and at the subtalar joint. In addition, high degree of coupling, primarily of internal rotation with inversion, was observed both at the ankle and at the subtalar joint. The in vitro motion produced in response to inversion and anterior drawer load was greater than the in vivo motion. Finally, external motion, measured directly across the ankle complex, produced in response to load was much greater than the bone movements measured through the 3D stress MRI technique indicating the significant effect of soft tissue and skin interference.

  1. Statistically-constrained shallow text marking: techniques, evaluation paradigm and results

    Science.gov (United States)

    Murphy, Brian; Vogel, Carl

    2007-02-01

    We present three natural language marking strategies based on fast and reliable shallow parsing techniques, and on widely available lexical resources: lexical substitution, adjective conjunction swaps, and relativiser switching. We test these techniques on a random sample of the British National Corpus. Individual candidate marks are checked for goodness of structural and semantic fit, using both lexical resources, and the web as a corpus. A representative sample of marks is given to 25 human judges to evaluate for acceptability and preservation of meaning. This establishes a correlation between corpus based felicity measures and perceived quality, and makes qualified predictions. Grammatical acceptability correlates with our automatic measure strongly (Pearson's r = 0.795, p = 0.001), allowing us to account for about two thirds of variability in human judgements. A moderate but statistically insignificant (Pearson's r = 0.422, p = 0.356) correlation is found with judgements of meaning preservation, indicating that the contextual window of five content words used for our automatic measure may need to be extended.

  2. Trochanteric osteotomies in revision total hip arthroplasty: contemporary techniques and results.

    Science.gov (United States)

    Jando, Victor T; Greidanus, Nelson V; Masri, Bassam A; Garbuz, Donald S; Duncan, Clive P

    2005-01-01

    Revision total hip arthroplasty (THA) presents several challenges to the orthopaedic surgeon and typically requires the use of a more extensile surgical approach. Osteotomy of the greater trochanter can be considered as the ultimate extensile exposure in revision THA. The methods of trochanteric osteotomy can be categorized into three types: the standard trochanteric osteotomy, the trochanteric slide, and the extended trochanteric osteotomy. Although the standard osteotomy and trochanteric slide osteotomy provide excellent acetabular exposure, in the revision setting they are frequently associated with an unacceptably high rate of nonunion and proximal migration of the trochanteric fragment. The extended trochanteric osteotomy (ETO) has increased in popularity as the number and complexity of revision THAs continue to increase. Two commonly used techniques are the ETO via a posterolateral approach or via a modified direct lateral approach. Both techniques provide wide exposure of the acetabulum, facilitate femoral component exposure and removal, aid in canal preparation and femoral reconstruction, and allow for correction of proximal femoral deformity. The osteotomy fragment is easily secured and may be advanced distally to achieve proper tensioning of the abductors. Recent literature demonstrates that the ETO has a relatively low rate of nonunion and is associated with fewer intraoperative femoral fractures or cortical perforations, as well as decreased surgical time.

  3. Introduction results of radiosurgery technique in cervical pathology consultation. Analysis of five years 2004 – 2009.

    Directory of Open Access Journals (Sweden)

    Rafael E. Pérez Castro

    2011-06-01

    Full Text Available AA cross sectional study and retrospective was performed in patients having cervical intraepithelial neoplasia (CIN, mainly in high grade lesions (CIN II, CIN III and C. In situ, which were treated with radiosurgery technique in the University General Hospital “Camilo Cienfuegos” Sancti Spiritus during the period may 2004 – may 2009 with the objective to evaluate the radiosurgery`s behaviour in the period mentioned before. The studied group was conformed by 550 patients having high grade lesions and low grade persistent lesions (NIC I with previous biopsy, a smaller group of 24 cases was formed by benign pathologies tributary of this procedure. High grade lesions were of major indications (73.1%. 69 cases were false negative (13.3%; since the second decade of life were presented high and low grade lesions of cervical pathology, a good correlation punch – cone byopsy was checked; edges of the surgical section behave properly, lower than what it is established in the international standard (6.7. The procedure had a great economic and social impact, because it is an ambulatory technique with few difficulties, low cost, and a fast integration patient – normal work.

  4. Problems at the Leading Edge of Space Weathering as Revealed by TEM Combined with Surface Science Techniques

    Science.gov (United States)

    Christoffersen, R.; Dukes, C. A.; Keller, L. P.; Rahman, Z.; Baragiola, R. A.

    2015-01-01

    Both transmission electron micros-copy (TEM) and surface analysis techniques such as X-ray photoelectron spectroscopy (XPS) were instrumen-tal in making the first characterizations of material generated by space weathering in lunar samples [1,2]. Without them, the nature of nanophase metallic Fe (npFe0) correlated with the surface of lunar regolith grains would have taken much longer to become rec-ognized and understood. Our groups at JSC and UVa have been using both techniques in a cross-correlated way to investigate how the solar wind contributes to space weathering [e.g., 3]. These efforts have identified a number of ongoing problems and knowledge gaps. Key insights made by UVa group leader Raul Barag-iola during this work are gratefully remembered.

  5. [Tibial defects and infected non-unions : Treatment results after Masquelet technique].

    Science.gov (United States)

    Moghaddam, A; Ermisch, C; Fischer, C; Zietzschmann, S; Schmidmaier, G

    2017-03-01

    The treatment of non-unions with large bone defects or osteitis is a major challenge in orthopedic and trauma surgery. A new concept of therapy is a two-step procedure: Masquelet technique according to the diamond concept. Between February 2010 and June 2014, 55 patients with tibia non-unions or infections were treated in a two-step Masquelet technique in our center. The patients' average age was 48 (median 50; minimum 15-maximum 72) with an average BMI (body mass index) of 28 (27; 18-52). There were 10 (18 %) female and 45 (82 %) male patients in the group. All study patients went through a follow up. Bone healing and clinical functional data were collected, as well as data according to subjective patient statements about pain and everyday limitations. In 42 cases (76.4 %) the outcome was a sufficient bony consolidation. On average, the time to heal was 10.3 (8, 5; 3-40) months, defect gaps were 4 cm (3 cm; 0,6-26 cm), and on average the patients had had 6 (median 4; range 1-31) previous operations . In all cases patients received osteosynthesis as well as a defect filling with RIA (reamer-irrigator-aspirator), and growth factor BMP-7 (bone morphogenetic protein-7). In 13 cases (23.6 %) there was no therapeutic success. In the evaluation of the SF12 questionnaire the mental health score increased from 47.4 (49.1; 27.6-65.7) to 49.8 (53.0; 28.7-69.4) and the well-being score from 32.7 (32.7;16.9-55.7) to 36.6 (36.5; 24.6-55.9). The two-step bone grafting method in the Masquelet technique used for tibia non-unions according to the diamond concept is a promising treatment option. Its application for tibia shaft non-unions with large bone defects or infections means a high degree of safety for the patient.

  6. ATR-FTIR spectroscopy reveals polycyclic aromatic hydrocarbon contamination despite relatively pristine site characteristics: Results of a field study in the Niger Delta.

    Science.gov (United States)

    Obinaju, Blessing E; Martin, Francis L

    2016-01-01

    Fourier-transform infrared (FTIR) spectroscopy is an emerging technique to detect biochemical alterations in biological tissues, particularly changes due to sub-lethal exposures to environmental contaminants. We have previously shown the potential of attenuated total reflection FTIR (ATR-FTIR) spectroscopy to detect real-time exposure to contaminants in sentinel organisms as well as the potential to relate spectral alterations to the presence of specific environmental agents. In this study based in the Niger Delta (Nigeria), changes occurring in fish tissues as a result of polycyclic aromatic hydrocarbon (PAH) exposure at contaminated sites are compared to the infrared (IR) spectra of the tissues obtained from a relatively pristine site. Multivariate analysis revealed that PAH contamination could be occurring at the pristine site, based on the IR spectra and significant (P<0.0001) differences between sites. The study provides evidence of the IR spectroscopy techniques' sensitivity and supports their potential application in environmental biomonitoring. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. [ECCE with self-sealing cataract incision. Technique and clinical results].

    Science.gov (United States)

    Pham, D T; Wollensak, J; Drosch, S

    1995-06-01

    We present of modified technique for sutureless ECCE with a trapezoidal tunnel incision of 11 mm. The operation can be performed in a closed system because of the self-sealing wound construction. Compared to the sutured corneoscleral ECCE the new procedure has important advantages: the procedure is safe even during the critical phase following nucleus extraction. The procedure is therefore safer, faster, more economical and suture-induced astigmatism is avoided. Clinical experience after 2 years showed that postoperative complications were reduced significantly. Iris prolapse, wound dehiscens and hyphema occurred at a rate of 2%. The astigmatism (Jaffe analysis) was at a rate of 2 D, stable within 4 weeks after surgery, and did not change up to 2 years postoperatively. The astigmatism induced was then reduced about 0.5 D by a radical suture.

  8. Early Results Show Reduced Infection Rate Using No-touch Technique for Expander/ADM Breast Reconstruction

    OpenAIRE

    Henry B. Wilson, MD, FACS

    2015-01-01

    Summary: Infection is a common complication of immediate breast reconstruction that often leads to device removal, a result emotionally devastating to the patient and frustrating for her surgeon. “No-touch” techniques have been used in other surgical disciplines and plastic surgery, but they have not been reported for breast reconstruction with tissue expanders or implants and acellular dermis. We report a novel technique of tissue expander and acellular dermis placement using no-touch princi...

  9. Percutaneous Nucleoplasty Using Coblation Technique for the Treatment of Chronic Nonspecific Low Back Pain: 5-year Follow-up Results

    Directory of Open Access Journals (Sweden)

    Da-Jiang Ren

    2015-01-01

    Conclusions: Although previously published short- and medium-term outcomes after percutaneous nucleoplasty appeared to be satisfactory, our long-term follow-up results show a significant decline in patient satisfaction over time. Percutaneous nucleoplasty is a safe and simple technique, with therapeutic effectiveness for the treatment of chronic LBP in selected patients. The technique is minimally invasive and can be used as part of a stepwise treatment plan for chronic LBP.

  10. Clinical and Histological Results of Vertical Ridge Augmentation of Atrophic Posterior Mandible with Inlay Technique of Cancellous Equine Bone Blocks

    OpenAIRE

    Pistilli R; Barausse C; Checchi L; Nannmark U; Felice P

    2013-01-01

    Aim: We want to evaluate a new bone block material in the inlay technique, for the vertical bone augmentation of a posterior atrophic mandible, in order to perfom aesthetic and prosthetic rehabilitation and enable implant insertion. Materials & Methods: Inlay technique and the subsequent successful implant rehabilitation in the atrophic right posterior mandible in a 42-year-old woman, was completed using a cancellous equine bone block as grafting material. Results: Three months after ...

  11. Preliminary results of the study on wind erosion in the Qinghai-Tibetan Plateau using 137Cs technique

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The worldwide fallout of caesium-137 (137Cs) associated with the nuclear weapon tests during the 1950s and 1960s has provided a valuable man-made tracer for studies of soil erosion and sediment delivery. But relatively few researchers have used it to estimate wind erosion. In this note, the 137Cs technique is introduced into the studies of wind erosion and its modern processes in the Qinghai-Tibetan Plateau. Two 137Cs reference inventories of 982.11 and 2 376.04 Bq·m-2 were established preminarily, distributed in the south and middle-north parts of the studied area respectively. By analyzing the patterns of 137Cs depth profiles from sampling sites, the aeolian processes of erosion and deposition in nearly 40 years have been revealed, i.e. the shrub coppice dunes (S1) and semi-fixed dunefields (S3) experienced the alternation of erosion and deposition, while the grasslands (S4, S6 and S7) and dry farmlands (S5) suffered erosion only. By using 137Cs model, the average wind erosion rates for shrub coppice dune (S1), semi-fixed dune fields (S3), dry farmlands (S5) and grasslands (S4, S6 and S7) were estimated to be 84.14, 69.43, 30.68 and 21.84 t·ha-1·a-1 respectively, averaging 47.59 t·ha-1·a-1 for the whole plateau, which can be regarded as of the medium erosion standard. These results derived from 137Cs for the first time have significant implications for the further research of wind erosion and desertification control in the Qinghai-Tibetan Plateau.

  12. Postpartum Hemorrhage Treated with Gelfoam Slurry Embolization Using the Superselective Technique: Immediate Results and 1-Month MRI Follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Pellerin, Olivier, E-mail: olivier.pellerin@egp.aphp.fr [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Bats, Anne-Sophie [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Gynecologic and Oncologic Surgery Department (France); Primio, Massimiliano Di; Palomera-Ricco, Ana [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Pinot de Villechenon, Gabrielle [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Anesthesia and Surgical Intensive Care Unit (France); and others

    2013-02-15

    To evaluate the efficacy and safety of superselective embolization of the uterine arteries in a postpartum hemorrhage. Between November 2004 and January 2011, a total of 44 consecutive women (median {+-} standard deviation age 34 {+-} 3 years, range 23-41 years) were referred to our institution for postpartum intractable hemorrhage management. All patients were embolized with a microcatheter that was placed deep into the uterine arteries upstream of the cervical arteries. The embolic agent was a mixture of contrast medium and 5 Multiplication-Sign 5 Multiplication-Sign 5 cm pieces of gelfoam (Gelita-Spon) modified into a gelatin emulsion as follows: rapid mixing through a three-way stopcock with two 2.5-ml syringes. A 1-ml syringe was used for injection. One month after embolization, all patients underwent magnetic resonance imaging and clinical examination. Technical and clinical success was obtained in all cases. Thirty-five patients experienced bleeding related to poor retraction of the uterus, 7 patients because of a tear of the cervix and 2 because of a vaginal hematoma. Pre- and postembolization red blood cell transfusions were (mean {+-} standard deviation [SD]) 6 {+-} 1.2 (range 3-8) U and 2 {+-} 0.7 (range 2-4) U, respectively. One-month magnetic resonance imaging follow-up revealed no sign of ischemic myometrium or necrosis, and no instances of uterine rupture and no pelvic vein thrombosis. Incidental findings included two small intramyometrial hematic collections. All uterine arteries were patent via magnetic resonance angiography. Seventeen patients had concomitant fibroids, all of which appeared hypovascular. This technique permits good, safe clinical results with no marked damage to the uterine arteries or the uterus itself.

  13. [Bernese periacetabular osteotomy. : Indications, technique and results 30 years after the first description].

    Science.gov (United States)

    Lerch, T D; Steppacher, S D; Liechti, E F; Siebenrock, K A; Tannast, M

    2016-08-01

    The Bernese periacetabular osteotomy (PAO) is a surgical technique for the treatment of (1) hip dysplasia and (2) femoroacetabular impingement due to acetabular retroversion. The aim of the surgery is to prevent secondary osteoarthritis by improvement of the hip biomechanics. In contrast to other pelvic osteotomies, the posterior column remains intact with this technique. This improves the inherent stability of the acetabular fragment and thereby facilitates postoperative rehabilitation. The birth canal remains unchanged. Through a shortened ilioinguinal incision, four osteotomies and one controlled fracture around the acetabulum are performed. The direction of acetabular reorientation differs for both indications while the sequence of the osteotomies remains the same. This surgical approach allows for a concomitant osteochondroplasty in the case of an aspherical femoral head-neck junction. The complication rate is relatively low despite the complexity of the procedure. The key point for a successful long term outcome is an optimal reorientation of the acetabulum for both indications. With an optimal reorientation and a spherical femoral head, the cumulative survivorship of the hip after 10 years is 80-90 %. For the very first 75 patients, the cumulative 20-year survivorship was 60 %. The preliminary evaluation of the same series at a 30-year follow-up still showed a survivorship of approximately 30 %. The PAO has become the standard procedure for the surgical therapy of hip dysplasia in adolescents and adults.

  14. Ultra-mini PNL (UMP): Material, indications, technique, advantages and results.

    Science.gov (United States)

    Desai, Janak D

    2017-01-01

    Stone disease has afflicted mankind since centuries; records from ancient civilisations of India and Egypt have shown stones in human bodies. The scientific mind of humans has always made smart endeavours to remove the kidney stones. From large instruments made like the beaks of different animals and birds in 600 BC (Indian civilisation) to extremely sophisticated and miniaturised endoscopic intruments of today the human race has travelled a long way. The theme has always been to remove the stones with minimal morbidity and mortality and with minimum pain to the patient. The article takes you through the journey of instruments used in 600 BC until today. The story of instrumentation is a symbiosis of the medical minds along with engineering advances. The story of miniaturisation could not have moved further without the development of lasers, fiberoptics and sophisticated cameras. As the field stands today, we remove more complex stones by larger endoscopic intervention and smaller stones by miniaturised instruments. The article discusses all the merits and shortcomings of various techniques: from open surgery to standard PCNL to Mini PCNL to Ultra- Mini PCNL to Micro-PCNL.

  15. Pulsed transthrombotic fibrinolysis: technique and results in the management of occluded lower limb bypass grafts.

    Science.gov (United States)

    Payelle, G; Maiza, D; Coffin, O; Alachkar, F; Alweis, S; Courtheoux, P; Khayat, M C; Gérard, J L; Théron, J

    1997-03-01

    Between March 1987 and March 1993 we used pulsed transthrombotic fibrinolysis to treat 58 symptomatic thrombotic occlusions of lower limb bypass grafts in 45 patients. There were 17 suprainguinal grafts and 28 infrainguinal grafts. Treatment consisted of pulsed infusion of fibrinolytic agents into the thrombus followed by continuous infusion using an electric pump. Minor percutaneous or surgical procedures were often associated. The mean delay to treatment was 7 days. The mean duration of treatment was 150 +/- 66 minutes. Immediate patency was achieved in 88% of cases with no significant difference between suprainguinal and infrainguinal grafts. The clinical success rate was 55%. Actuarial patency at 1 year was 54% +/- 11% for suprainguinal grafts and 26% +/- 7% for infrainguinal grafts. The probability of patency was much lower in patients whose grafts had been implanted within 3 months before occlusion and in patients in whom an adjuvant procedure had not been performed. This study demonstrates that, in cases not requiring immediate surgery, pulsed transthrombotic fibrinolysis can achieve durable patency by treating both the bypass and distal arterial network. This technique allows identification of lesions causing thrombosis and adaptation of treatment specifically to these lesions.

  16. Low-field MR arthrography of the shoulder joint: technique, indications, and clinical results

    Energy Technology Data Exchange (ETDEWEB)

    Kreitner, K.-F.; Thelen, M. [Department of Radiology, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz (Germany); Loew, R. [Department of Radiology, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz (Germany); Department of Radiology, University Hospital, 1201 Basel (Switzerland); Runkel, M. [Department of Traumatology, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz (Germany); Department of Traumatology and Hand Surgery, Klinikum Konstanz, Konstanz (Germany); Zoellner, J. [Department of Orthopedic Surgery, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz (Germany)

    2003-02-01

    In the age of cost containment and urgent reductions in health care expenditures, new options have to be explored to satisfy both diagnostic requirements and economic limitations. The introduction of low-field MR systems for assessment of joint disorders seemed to be an option for lower costs. The purpose of this article is to summarize available experiences with low-field MR arthrography of the glenohumeral joint with respect to image quality and diagnostic accuracy in detecting labral and rotator cuff lesions. Up to now, there has been only a limited number of studies available dealing with low-field MR arthrography of the glenohumeral joint. They reveal that, despite a minor image quality in comparison with high-field imaging, low-field MR arthrography of the shoulder allows for sufficient evaluation of intra- and extra-articular structures in the detection of major abnormalities such as glenohumeral instability or rotator cuff disease. Furthermore, open-configured MR scanners enable kinematic studies: Besides the analysis of normal motion, pathological findings in patients with instabilities and impingement syndrome can be delineated. They further offer the possibility for performing MR imaging-guided arthrography of the shoulder. This was first described using an open C-arm scanner with a vertically oriented magnetic field so that MR arthrography may be performed in one setting. (orig.)

  17. Restoration of horizontal stability in complete acromioclavicular joint separations: surgical technique and preliminary results.

    Science.gov (United States)

    Li, Haoqing; Wang, Chuanshun; Wang, Jiandong; Wu, Kai; Hang, Donghua

    2013-11-13

    Our purpose was to investigate the clinical efficacy of arthroscope-assisted acromioclavicular ligament reconstruction in combination with double endobutton coracoclavicular ligament reconstruction for the treatment of complete acromioclavicular joint dislocation. During the period from February 2010 to October 2012, ten patients with Rockwood types IV and V acromioclavicular joint dislocation were hospitalized and nine were treated with acromioclavicular ligament reconstruction combined with double endobutton of coracoclavicular ligament reconstruction. The improvement in shoulder functions was assessed using a Constant score and visual analog scale (VAS) system. The mean follow-up period was 33.6 ± 5.4 months. The mean Constant scores improved from 25.2 ± 6.6 preoperatively to 92.4 ± 6.5 postoperatively, while the mean VAS score decreased from 5.9 ± 1.4 to 1.2 ± 0.9; significant differences were observed. The final follow-up revealed that excellent outcomes were achieved in eight patients and good outcome in two patients. Arthroscope-assisted acromioclavicular ligament reconstruction in combination with double endobutton of coracoclavicular ligament reconstruction is an effective approach for treatment of acute complete acromioclavicular joint dislocation.

  18. Korean round-robin result for new international program to assess the reliability of emerging nondestructive techniques

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyung Cho; Kim, Jin Gyum; Kang, Sung Sik; Jhung, Myung Jo [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2017-04-15

    The Korea Institute of Nuclear Safety, as a representative organization of Korea, in February 2012 participated in an international Program to Assess the Reliability of Emerging Nondestructive Techniques initiated by the U.S. Nuclear Regulatory Commission. The goal of the Program to Assess the Reliability of Emerging Nondestructive Techniques is to investigate the performance of emerging and prospective novel nondestructive techniques to find flaws in nickel-alloy welds and base materials. In this article, Korean round-robin test results were evaluated with respect to the test blocks and various nondestructive examination techniques. The test blocks were prepared to simulate large-bore dissimilar metal welds, small-bore dissimilar metal welds, and bottom-mounted instrumentation penetration welds in nuclear power plants. Also, lessons learned from the Korean round-robin test were summarized and discussed.

  19. Korean Round-Robin Tests Result for New International Program to Assess the Reliability of Emerging Nondestructive Techniques

    Directory of Open Access Journals (Sweden)

    Kyung Cho Kim

    2017-04-01

    Full Text Available The Korea Institute of Nuclear Safety, as a representative organization of Korea, in February 2012 participated in an international Program to Assess the Reliability of Emerging Nondestructive Techniques initiated by the U.S. Nuclear Regulatory Commission. The goal of the Program to Assess the Reliability of Emerging Nondestructive Techniques is to investigate the performance of emerging and prospective novel nondestructive techniques to find flaws in nickel-alloy welds and base materials. In this article, Korean round-robin test results were evaluated with respect to the test blocks and various nondestructive examination techniques. The test blocks were prepared to simulate large-bore dissimilar metal welds, small-bore dissimilar metal welds, and bottom-mounted instrumentation penetration welds in nuclear power plants. Also, lessons learned from the Korean round-robin test were summarized and discussed.

  20. Clustering the Results of Brainstorm Sessions: Applying Word Similarity Techniques to Cluster Dutch Nouns

    NARCIS (Netherlands)

    Amrit, Chintan Amrit; Hek, Jeroen

    2016-01-01

    This research addresses the problem of clustering the results of brainstorm sessions. Going through all ideas and clustering them can be a time consuming task. In this research we design a computer-aided approach that can help with clustering of these results. We have limited ourselves to looking at

  1. Clustering the Results of Brainstorm Sessions: Applying Word Similarity Techniques to Cluster Dutch Nouns

    NARCIS (Netherlands)

    Amrit, Chintan; Hek, Jeroen

    2016-01-01

    This research addresses the problem of clustering the results of brainstorm sessions. Going through all ideas and clustering them can be a time consuming task. In this research we design a computer-aided approach that can help with clustering of these results. We have limited ourselves to looking at

  2. Parallel Comparison of N-Linked Glycopeptide Enrichment Techniques Reveals Extensive Glycoproteomic Analysis of Plasma Enabled by SAX-ERLIC.

    Science.gov (United States)

    Totten, Sarah M; Feasley, Christa L; Bermudez, Abel; Pitteri, Sharon J

    2017-03-03

    Protein glycosylation is of increasing interest due to its important roles in protein function and aberrant expression with disease. Characterizing protein glycosylation remains analytically challenging due to its low abundance, ion suppression issues, and microheterogeneity at glycosylation sites, especially in complex samples such as human plasma. In this study, the utility of three common N-linked glycopeptide enrichment techniques is compared using human plasma. By analysis on an LTQ-Orbitrap Elite mass spectrometer, electrostatic repulsion hydrophilic interaction liquid chromatography using strong anion exchange solid-phase extraction (SAX-ERLIC) provided the most extensive N-linked glycopeptide enrichment when compared with multilectin affinity chromatography (M-LAC) and Sepharose-HILIC enrichments. SAX-ERLIC enrichment yielded 191 unique glycoforms across 72 glycosylation sites from 48 glycoproteins, which is more than double that detected using other enrichment techniques. The greatest glycoform diversity was observed in SAX-ERLIC enrichment, with no apparent bias toward specific glycan types. SAX-ERLIC enrichments were additionally analyzed by an Orbitrap Fusion Lumos mass spectrometer to maximize glycopeptide identifications for a more comprehensive assessment of protein glycosylation. In these experiments, 829 unique glycoforms were identified across 208 glycosylation sites from 95 plasma glycoproteins, a significant improvement from the initial method comparison and one of the most extensive site-specific glycosylation analysis in immunodepleted human plasma to date. Data are available via ProteomeXchange with identifier PXD005655.

  3. Molecular Techniques Revealed Highly Diverse Microbial Communities in Natural Marine Biofilms on Polystyrene Dishes for Invertebrate Larval Settlement

    KAUST Repository

    Lee, On On

    2014-01-09

    Biofilm microbial communities play an important role in the larval settlement response of marine invertebrates. However, the underlying mechanism has yet to be resolved, mainly because of the uncertainties in characterizing members in the communities using traditional 16S rRNA gene-based molecular methods and in identifying the chemical signals involved. In this study, pyrosequencing was used to characterize the bacterial communities in intertidal and subtidal marine biofilms developed during two seasons. We revealed highly diverse biofilm bacterial communities that varied with season and tidal level. Over 3,000 operational taxonomic units with estimates of up to 8,000 species were recovered in a biofilm sample, which is by far the highest number recorded in subtropical marine biofilms. Nineteen phyla were found, of which Cyanobacteria and Proteobacteria were the most dominant one in the intertidal and subtidal biofilms, respectively. Apart from these, Actinobacteria, Bacteroidetes, and Planctomycetes were the major groups recovered in both intertidal and subtidal biofilms, although their relative abundance varied among samples. Full-length 16S rRNA gene clone libraries were constructed for the four biofilm samples and showed similar bacterial compositions at the phylum level to those revealed by pyrosequencing. Laboratory assays confirmed that cyrids of the barnacle Balanus amphitrite preferred to settle on the intertidal rather than subtidal biofilms. This preference was independent of the biofilm bacterial density or biomass but was probably related to the biofilm community structure, particularly, the Proteobacterial and Cyanobacterial groups. © 2014 Springer Science+Business Media New York.

  4. Iliac crest allograft glenoid reconstruction for recurrent anterior shoulder instability in athletes: Surgical technique and results

    Directory of Open Access Journals (Sweden)

    Randy Mascarenhas

    2014-01-01

    Full Text Available Performing a labral repair alone in patients with recurrent anterior instability and a large glenoid defect has led to poor outcomes. We present a technique involving the use of the iliac crest allograft inserted into the glenoid defect in athletes with recurrent anterior shoulder instability and large bony defects of the glenoid (>25% of glenoid diameter. All athletes with recurrent anterior shoulder instability and a large glenoid defect that underwent open anterior shoulder stabilization and glenoid reconstruction with the iliac crest allograft were followed over a 4-year period. Preoperatively, a detailed history and physical exam were obtained along with standard radiographs and magnetic resonance imaging of the affected shoulder. All patients also completed the Simple Shoulder Test (SST and American Shoulder and Elbow Surgeons (ASES evaluation forms preoperatively. A computed tomography scan was obtained postoperatively to assess osseous union of the graft and the patient again went through a physical exam in addition to completing the SST, ASES, and Western Ontario Shoulder Instability Index (WOSI forms. 10 patients (9 males, 1 female were followed for an average of 16 months (4-36 months and had a mean age of 24.4 years. All patients exhibited a negative apprehension/relocation test and full shoulder strength at final follow-up. Eight of 10 patients had achieved osseous union at 6 months (80.0%. ASES scores improved from 64.3 to 97.8, and SST scores improved from 66.7 to 100. Average postoperative WOSI scores were 93.8%. The use of the iliac crest allograft provides a safe and clinically useful alternative compared to previously described procedures for recurrent shoulder instability in the face of glenoid deficiency.

  5. Mucosal proctectomy and ileoanal pull-through technique and functional results in 23 consecutive patients.

    Science.gov (United States)

    Bodzin, J H; Kestenberg, W; Kaufmann, R; Dean, K

    1987-07-01

    Mucosal proctectomy with ileoanal pull-through in the treatment of ulcerative colitis and familial polyposis provides a technique for the preservation of the anal sphincters and relatively normal mechanisms of continence. Five patients had straight ileoanal anastomosis while 18 had the construction of a J-pouch. A two-team approach was used for simultaneous abdominal and perineal procedures to facilitate a shortened operating time. A loop ileostomy was routinely used in the postoperative period and was closed an average of 4.5 months (range: 2-16 months) later without complication. Prolonged preoperative hospitalization was rarely necessary and outpatient steroid enema preparation was routinely used. There were no deaths. Nineteen patients with functioning pull-through procedures have been followed an average of 23 months (range: 3-42 months). Two other patients have not had ileostomy closure because of complications. The two remaining patients had intractable diarrhea and have since undergone conversion to a permanent ileostomy. The 19 patients are continent, having three to nine bowel movements each day. Nearly all wear a perineal sanitary pad because of rare, unpredictable leakage of small amounts of fluid, especially at night. Complications were significant in this group of patients. Intestinal obstruction was a frequent problem, occurring in 52 per cent of the entire series and necessitating reoperation in 22 per cent. Anal stricture was a problem in another five patients. A variety of other minor problems occurred and most were treated nonoperatively. In spite of moderate diarrhea and occasional leakage of stool, all patients with functioning pull-through procedures prefer their current status to life with an ileostomy.(ABSTRACT TRUNCATED AT 250 WORDS)

  6. Modified urethrovesical anastomosis during robot-assisted simple prostatectomy: Technique and results

    Directory of Open Access Journals (Sweden)

    Octavio Castillo

    2016-06-01

    Conclusion: The results of our study show that RASP with UVA is a feasible, secure, and reproducible procedure with low morbidity. Additional series with larger patient cohorts are needed to validate this approach.

  7. Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture-based techniques

    DEFF Research Database (Denmark)

    Friis-Holm, Lotte Bjerrum; Engberg, R.M.; Leser, T.D.

    2006-01-01

    The microbial communities of the ileum and cecum of broiler chickens from a conventional and an organic farm were investigated using conventional culture techniques as well as cloning and sequencing of 16S rRNA genes. Eighty-five percent of the 557 cloned sequences were ...% of the cecal clones belonged to this cluster in conventional and organic broiler chickens, respectively. We were, however, able to recover a number of these phylotypes by cultivation, and the isolates were shown to be butyric acid producers. The investigation was a descriptive rather than a comparative study...... of 2 different rearing systems; however, several differences were observed. For instance, Clostridium perfringens was found in significantly higher numbers in the birds from the organic farm compared with the conventional broilers, probably due to the addition of salinomycin to the conventional feed...

  8. Survey of the results of acute sciatic nerve repair comparing epineural and perineurial techniques in the lower extremities of rat

    Institute of Scientific and Technical Information of China (English)

    Hamid Karimi; Kamal Seyed Forootan; Gholamreza Moein; Seyed Jaber Mosavi; Batol Ghorbani Iekta

    2015-01-01

    Objective: To study the result of nerve repair in the two mentioned techniques in rats to find the proper answer to the existing disagreement. Methods: Twenty adult male rats were included in treatment group. Acutely disconnected sciatic nerve was repaired by Epineural technique in half of the rats;in the other half perineurial technique was applied. After 80 d, the number of grown axons of distal on the repair site was calculated through the use of an optical microscope. Additionally by studying the foot print of the rats the return of neural motor activity was evaluated. Results: In epineural group, SFI index was: (56.33±32.30) and in perineurial group: (55.71±30.31);P value=0.930 with their being no difference between these two techniques of surgery. However, in comparing epineural and perineurial groups in the groups themselves, statistical tests showed a significant difference showing functional improvement in comparison with the day before surgery P value=0.0001. Statistical tests showed that the average of axons' number distal to anastomosis site in the epineural group was (349±80) and in the perineurial group was (405±174). These groups have no significant difference regarding the number of axons (P value=0.36). Conclusion:The results of epineural and perineurial surgery techniques show no difference in nerve repair, SFI index, or axon counting in distal part.

  9. Platelet-Rich Fibrin (PRF) in Implants Dentistry in Combination with New Bone Regenerative Flapless Technique: Evolution of the Technique and Final Results.

    Science.gov (United States)

    Cortese, Antonio; Pantaleo, Giuseppe; Amato, Massimo; Howard, Candace M; Pedicini, Lorenzo; Claudio, Pier Paolo

    2017-01-01

    Most common techniques for alveolar bone augmentation are guided bone regeneration (GBR) and autologous bone grafting. GBR studies demonstrated long-term reabsorption using heterologous bone graft. A general consensus has been achieved in implant surgery for a minimal amount of 2 mm of healthy bone around the implant. A current height loss of about 3-4 mm will result in proper deeper implant insertion when alveolar bone expansion is not planned because of the dome shape of the alveolar crest. To manage this situation a split crest technique has been proposed for alveolar bone expansion and the implants' insertion in one stage surgery. Platelet-rich fibrin (PRF) is a healing biomaterial with a great potential for bone and soft tissue regeneration without inflammatory reactions, and may be used alone or in combination with bone grafts, promoting hemostasis, bone growth, and maturation. The aim of this study was to demonstrate the clinical effectiveness of PRF combined with a new split crest flapless modified technique in 5 patients vs. 5 control patients. Ten patients with horizontal alveolar crests deficiency were treated in this study, divided into 2 groups: Group 1 (test) of 5 patients treated by the flapless split crest new procedure; Group 2 (control) of 5 patients treated by traditional technique with deeper insertion of smaller implants without split crest. The follow-up was performed with x-ray orthopantomography and intraoral radiographs at T0 (before surgery), T1 (operation time), T2 (3 months) and T3 (6 months) post-operation. All cases were successful; there were no problems at surgery and post-operative times. All implants succeeded osteointegration and all patients underwent uneventful prosthetic rehabilitation. Mean height bone loss was 1 mm, measured as bone-implant most coronal contact (Δ-BIC), and occurred at immediate T2 post-operative time (3 months). No alveolar bone height loss was detected at implant insertion time, which was instead

  10. Tools, Techniques, and Training: Results of an E-Resources Troubleshooting Survey

    Science.gov (United States)

    Rathmel, Angela; Mobley, Liisa; Pennington, Buddy; Chandler, Adam

    2015-01-01

    A primary role of any e-resources librarian or staff is troubleshooting electronic resources (e-resources). While much progress has been made in many areas of e-resources management (ERM) to understand the ERM lifecycle and to manage workflows, troubleshooting access remains a challenge. This collaborative study is the result of the well-received…

  11. Scapular allograft reconstruction after total scapulectomy: surgical technique and functional results

    NARCIS (Netherlands)

    Capanna, R.; Totti, F.; Geest, I.C.M. van der; Muller, D.A.

    2015-01-01

    HYPOTHESIS: Scapular allograft reconstruction after total scapulectomy preserving the rotator cuff muscles is an oncologically safe procedure and results in good functional outcome with a low complication rate. METHODS: The data of 6 patients who underwent scapular allograft reconstruction after a

  12. Treatment of simple bone cysts by topical infiltrations of methylprednisolone acetate: Technique and results

    Energy Technology Data Exchange (ETDEWEB)

    Carrata, A.; Garbagna, P.; Mapelli, S.; Zucchi, V.

    1983-02-01

    The authors report their experience in the percutaneous treatment of simple bone cysts by intra-cystic local infiltrations of methylprednisolone acetate. In particular, the method adopted, the evolution of the radiologic picture and the results, achieved are described. Sixty patients were successfully treated without complications or surgery.

  13. SURGICAL TECHNIQUE, SHORT- AND LONG-TERM RESULTS OF THE HORSESHOE KIDNEY TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    Sh. R. Galeev

    2015-01-01

    Full Text Available The experience of horseshoe kidney transplant operations is significantly restricted. Transplant surgeons often refuse to use horseshoe kidney due to a number of serious abnormalities of vessels and upper urinary tract in these organs. However, the constant shortage of donor organs and an increase in patients on the waiting list for kidney transplantation make us reconsider our approach to the selection of donor organs. The aim of this work was to demonstrate our result of horseshoe kidney transplantation. 

  14. Clinical Results After Prostatic Artery Embolization Using the PErFecTED Technique: A Single-Center Study

    Energy Technology Data Exchange (ETDEWEB)

    Amouyal, Gregory, E-mail: gregamouyal@hotmail.com; Thiounn, Nicolas, E-mail: nicolas.thiounn@aphp.fr; Pellerin, Olivier, E-mail: olivier.pellerin@aphp.fr [Université Paris Descartes - Sorbonne - Paris - Cité, Faculté de Médecine (France); Yen-Ting, Lin, E-mail: ymerically@gmail.com [Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Interventional Radiology Department (France); Giudice, Costantino Del, E-mail: costantino.delgiudice@aphp.fr [Université Paris Descartes - Sorbonne - Paris - Cité, Faculté de Médecine (France); Dean, Carole, E-mail: carole.dean@aphp.fr [Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Interventional Radiology Department (France); Pereira, Helena, E-mail: helena.pereira@aphp.fr [Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Clinical Research Unit (France); Chatellier, Gilles, E-mail: gilles.chatellier@aphp.fr; Sapoval, Marc, E-mail: marc.sapoval2@aphp.fr [Université Paris Descartes - Sorbonne - Paris - Cité, Faculté de Médecine (France)

    2016-03-15

    BackgroundProstatic artery embolization (PAE) has been performed for a few years, but there is no report on PAE using the PErFecTED technique outside from the team that initiated this approach.ObjectiveThis single-center retrospective open label study reports our experience and clinical results on patients suffering from symptomatic BPH, who underwent PAE aiming at using the PErFecTED technique.Materials and MethodsWe treated 32 consecutive patients, mean age 65 (52–84 years old) between December 2013 and January 2015. Patients were referred for PAE after failure of medical treatment and refusal or contra-indication to surgery. They were treated using the PErFecTED technique, when feasible, with 300–500 µm calibrated microspheres (two-night hospital stay or outpatient procedure). Follow-up was performed at 3, 6, and 12 months.ResultsWe had a 100 % immediate technical success of embolization (68 % of feasibility of the PErFecTED technique) with no immediate complications. After a mean follow-up of 7.7 months, we observed a 78 % rate of clinical success. Mean IPSS decreased from 15.3 to 4.2 (p = .03), mean QoL from 5.4 to 2 (p = .03), mean Qmax increased from 9.2 to 19.2 (p = .25), mean prostatic volume decreased from 91 to 62 (p = .009) mL. There was no retrograde ejaculation and no major complication.ConclusionPAE using the PErFecTED technique is a safe and efficient technique to treat bothersome LUTS related to BPH. It is of interest to note that the PErFecTED technique cannot be performed in some cases for anatomical reasons.

  15. Polymorphism of omega-gliadins in durum wheat as revealed by the two-step APAGE/SDS-PAGE technique.

    Science.gov (United States)

    Nieto-Taladriz, M T; Branlard, G; Dardevet, M

    1994-03-01

    Polymorphism of omega-gliadins was studied in 243 durum wheats from 27 countries using the two-step one-dimensional APAGE/SDS-PAGE technique. A total of 12 bands of different mobility were observed, and four of them were found to be different from those previously detected by Khelifi et al. (1992) in bread wheat. Fifteen alleles, six coded by the Gli-A1 locus and nine coded by the Gli-B1 locus, were identified, accounting for 19 different electrophoretic patterns. Seven new alleles were detected: two at the Gli-A1 locus and five at the Gli-B1 locus. The polymorphism found at the Gli-A1 and Gli-B1 loci was slightly greater than that found in bread wheat. Allelic differences between both species were higher at the Gli-B1 locus. A comparison of the frequencies of alleles in both species was carried out. The null allele, Gli-A1e, was more common in durum wheat than in bread wheat. The Gli-B1b allele, present in 60% of the bread wheats, was found in only 2% of the durum wheats and Gli-B1e, very common in durum wheat (45%), was rare in bread wheat (4%). The Gli-B1IV allele, common in durum wheat (28%), was not detected in bread wheat.

  16. [Conservative surgery for supraglottic carcinoma. Surgical technique. Oncologic and functional results].

    Science.gov (United States)

    Vega, S F; Scola, B; Vega, M F; Martinez, T; Scola, E

    1996-08-01

    We present the results of a retrospective study of 817 patients treated with conservative surgery for carcinomas of the supraglottic larynx at ENT department of the Gregorio Maranón Hospital between 1962-1993. The disease was staged using the criteria set forth in 1988 by the AJCC, and 36,2% were stages III and IV. From the 817 patients treated with conservative surgery 230 were extended supraglottic laryngectomies. Our theoretic treatment protocol is presented. The 5 years actuarial uncorrected survival rate related to stage was 83,9%, 83,2%, 78,5% and 55,3% for stages I, II, III and IV respectively. Local-regional failure occurred in 32,9% patients overall, and the most common site for local-regional failure was the cervical nodes. The 5 years local control rate related to stage was 86,97%, 89,1%, 82,15% and 66,55% for stages I, II, III and IV respectively. In extended supraglottic laryngectomies the 5 years uncorrected survival rate was 62,6% in supraglottic laryngectomies (SL) extended to the base of the tongue, 62,5% in SL extended to the hypopharynx, 72,5% in SL extended to the arythenoyd and 79,4% in SL extended to the vocal chord. The 5 years local control rate was 87% in SL extended to the base of the tongue, 85,7% in SL extended to the hypopharynx, 97% in SL extended to the arythenoid and 90,8% in SL extended to the vocal chord. Functional results have been evaluated according to a three grade scale. Good and fair results were 97.6% for swallowing, 90% for respiration and 95.8% for the quality of voice.

  17. Changes in Selected Biochemical Indices Resulting from Various Pre-sampling Handling Techniques in Broilers

    Directory of Open Access Journals (Sweden)

    Chloupek Petr

    2011-05-01

    Full Text Available Abstract Background Since it is not yet clear whether it is possible to satisfactorily avoid sampling-induced stress interference in poultry, more studies on the pattern of physiological response and detailed quantification of stress connected with the first few minutes of capture and pre-sampling handling in poultry are required. This study focused on detection of changes in the corticosterone level and concentrations of other selected biochemical parameters in broilers handled in two different manners during blood sampling (involving catching, carrying, restraint, and blood collection itself that lasted for various time periods within the interval 30-180 seconds. Methods Stress effects of pre-sampling handling were studied in a group (n = 144 of unsexed ROSS 308 broiler chickens aged 42 d. Handling (catching, carrying, restraint, and blood sampling itself was carried out in a gentle (caught, held and carried carefully in an upright position or rough (caught by the leg, held and carried with lack of care in inverted position manner and lasted for 30 s, 60 s, 90 s, 120 s, 150 s, and 180 s. Plasma corticosterone, albumin, glucose, cholesterol, lactate, triglycerides and total protein were measured in order to assess the stress-induced changes to these biochemical indices following handling in the first few minutes of capture. Results Pre-sampling handling in a rough manner resulted in considerably higher plasma concentrations of all biochemical indices monitored when compared with gentle handling. Concentrations of plasma corticosterone after 150 and 180 s of handling were considerably higher (P Conclusions These results indicate that the pre-sampling procedure may be a considerably stressful procedure for broilers, particularly when carried out with lack of care and exceeding 120 seconds.

  18. Multidetector computed tomography of urolithiasis. Technique and results; Multidetektor-Computertomografie der Urolithiasis. Technik und Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Karul, M.; Regier, M. [Universitaetsklinikum Hamburg-Eppendorf, Hamburg (Germany). Zentrum fuer Radiologie und Endoskopie; Heuer, R. [Universitaetsklinikum Hamburg-Eppendorf, Hamburg (Germany). Zentrum fuer Operative Medizin

    2013-02-15

    The diagnosis of acute urolithiasis results from unenhanced multidetector computed tomography (MDCT). This test analyses the functional and anatomical possibility for passing an ureteral calculi, the localization and dimension of which are important parameters for further therapy. Alternatively chronic urolithiasis could be ruled out by magnetic resonance urography (MRU). MRU is the first choice especially in pregnant women and children because of radiation hygiene. Enhanced MDCT must be emphasized as an alternative to intravenous urography (IVU) for diagnosis of complex drainage of urine and suspected disorder of the involved kidney. This review illustrates the principles of different tests and the clinical relevance thereof. (orig.)

  19. [Distraction osteogenesis in the midface. Indications, technique and first long-term results].

    Science.gov (United States)

    Kessler, Peter; Kloss, Frank; Hirschfelder, Ursula; Neukam, Friedrich Wilhelm; Wiltfang, Jörg

    2003-01-01

    Since the beginning of 1998, eleven patients have been treated by osteodistraction to correct hypoplasia of the maxilla and midface of various origins. Among them were six patients who were treated by high LeFort I osteotomies and insertion of subcutaneous intraoral distraction devices in the malar region. In the remaining five patients extraoral distraction devices were applied after LeFort I, II and III osteotomies. Distraction osteogenesis was successful in all cases, resulting in a mean sagittal bone gain measured parallel to the skull base of 9.5 mm (range 4.5-12.0) in the group treated with intraoral distractors and a mean of 19.4 mm in the extraoral distraction group (range 15.0-25.0). All patients were kept under orthodontic supervision before, during, and after osteodistraction. In eight patients long-term cephalometric and clinical evaluation after a mean follow-up period of 24 months in the intraoral distraction group (range 22-26) and 12 months in the extraoral distraction group (range 10-14) show stable results concerning the skeletal and dental relations. Long-term follow-up is necessary.

  20. Comparison of the results of MIS-TLIF and open TLIF techniques in laborers

    Directory of Open Access Journals (Sweden)

    Daniel De Abreu Oliveira

    2014-01-01

    Full Text Available Objective: To compare clinical outcomes in laborers who have undergone open transforaminal interbody fusion (TLIF and minimally invasive transforaminal interbody fusion (MIS TLIF. Methods: 78 patients were submitted to lumbar arthrodesis by the same two spine surgeons partners from January 2008 to December 2012. Forty-one were submitted to traditional open arthrodesis and 37 to the minimally invasive procedure. Three patients were not included because they had already retired from work. The analyzed variables were length of hospitalization, length of follow-up, type of access (TILF or MIS TLIF, need for blood transfusion, percentage of improvement or worsening after surgery, pre- and postoperative VAS scale, time off work, pre-and postoperative Oswestry disability index, and general aspects of the laborers such as age, education, profession, working time, amount of daily weight carried at work, and use or not of personal protective equipment. Results: Time off work was longer in the TLIF group (average of 9.84 months compared with the MIS TLIF group (average of 3.20 months. Significant improvement in postoperative VAS and Oswestry was achieved in both groups. Average length of hospitalization was 5.73 days for the TLIF group and 2.76 days for the MIS TLIF group. Conclusions: Minimally invasive transforaminal lumbar interbody fusion presents similar results when compared to open TLIF, but has the benefits of less postoperative morbidity, shorter hospitalization times, and faster rehabilitation in laborer patients.

  1. GLOBAL CONVERGENCE RESULTS OF A THREE TERM MEMORY GRADIENT METHOD WITH A NON-MONOTONE LINE SEARCH TECHNIQUE

    Institute of Scientific and Technical Information of China (English)

    Sun Qingying

    2005-01-01

    In this paper, a new class of three term memory gradient method with nonmonotone line search technique for unconstrained optimization is presented. Global convergence properties of the new methods are discussed. Combining the quasi-Newton method with the new method, the former is modified to have global convergence property. Numerical results show that the new algorithm is efficient.

  2. Angiography of the temporomandibular joint. Description of an experimental technique with initial results.

    Science.gov (United States)

    Takagi, R; Shimoda, T; Westesson, P L; Takahashi, A; Morris, T W; Sano, T; Moses, J J

    1994-10-01

    The vascular supply to the temporomandibular joint is not completely understood. To form a base for advancement in this area we developed a method for experimental angiography of the temporomandibular joint that was applied to fresh temporomandibular joint autopsy specimens. Via the external carotid artery the vessels were infused with a mixture of barium and an acrylic resin. The specimens were sectioned and contact radiographs were obtained. These showed the vascularity of the joint and the surrounding structures with great detail. Most of the vascular supply appears to come from the lateral and medial aspects of the condyle head and from the anterior and posterior disk attachments. The method was applied to both normal and abnormal joints and the results suggest that this method could be used to gather further understanding of the vascularity of the temporomandibular joint relative to disease.

  3. Contact therapy in the region of pharynx and oral cavity: Afterloading technique, irradiation planning, and results

    Energy Technology Data Exchange (ETDEWEB)

    Fritz, P.; Bauer, M.; Fehrentz, D.; Zum Winkel, K.; Weidauer, H.; Singer, R.

    1985-05-01

    The contact irradiation in the region of pharynx and mouth with an afterloading unit is presented. Twelve patients with recurrent carcinomas of the squamous cell epithelium have been treated. A stable and reproducible positioning of the source probes in the tumor region is made possible by special applicator prostheses which are adapted to the post-operative situation. The irradiation scheme is based on the transformation of the source co-ordinates from the stereoradiographic localization system into the co-ordinate system of the computed tomogram. At least three fixed metal points which are inserted in the applicator prostheses and visualized by stereoradiography as well as by computed tomography serve as mutual reference points for both co-ordinate systems. The source positioning in the tumor region is optimized by CT irradiation planning. Three cases are presented in order to describe the principles of the method. Preliminary results are discussed.

  4. Thermodynamic Spectrum of Solar Flares Based on SDO/EVE Observations: Techniques and First Results

    Science.gov (United States)

    Wang, Yuming; Zhou, Zhenjun; Zhang, Jie; Liu, Kai; Liu, Rui; Shen, Chenglong; Chamberlin, Phillip C.

    2016-01-01

    The Solar Dynamics Observatory (SDO)/EUV Variability Experiment (EVE) provides rich information on the thermodynamic processes of solar activities, particularly on solar flares. Here, we develop a method to construct thermodynamic spectrum (TDS) charts based on the EVE spectral lines. This tool could potentially be useful for extreme ultraviolet (EUV) astronomy to learn about the eruptive activities on distant astronomical objects. Through several cases, we illustrate what we can learn from the TDS charts. Furthermore, we apply the TDS method to 74 flares equal to or greater than the M5.0 class, and reach the following statistical results. First, EUV peaks are always behind the soft X-ray (SXR) peaks and stronger flares tend to have faster cooling rates. There is a power-law correlation between the peak delay times and the cooling rates, suggesting a coherent cooling process of flares from SXR to EUV emissions. Second, there are two distinct temperature drift patterns, called Type I and Type II. For Type I flares, the enhanced emission drifts from high to low temperature like a quadrilateral, whereas for Type II flares the drift pattern looks like a triangle. Statistical analysis suggests that Type II flares are more impulsive than Type I flares. Third, for late-phase flares, the peak intensity ratio of the late phase to the main phase is roughly correlated with the flare class, and the flares with a strong late phase are all confined. We believe that the re-deposition of the energy carried by a flux rope, which unsuccessfully erupts out, into thermal emissions is responsible for the strong late phase found in a confined flare. Furthermore, we show the signatures of the flare thermodynamic process in the chromosphere and transition region in the TDS charts. These results provide new clues to advance our understanding of the thermodynamic processes of solar flares and associated solar eruptions, e.g., coronal mass ejections.

  5. Extended endoscopic endonasal transsphenoidal approach for retrochiasmatic craniopharyngioma: Surgical technique and results

    Directory of Open Access Journals (Sweden)

    Suresh K Sankhla

    2015-01-01

    Full Text Available Objective: Surgical treatment of retrochiasmatic craniopharyngioma still remains a challenge. While complete removal of the tumor with preservation of the vital neurovascular structures is often the goal of the treatment, there is no optimal surgical approach available to achieve this goal. Transcranial and transsphenoidal microsurgical approaches, commonly used in the past, have considerable technical limitations. The extended endonasal endoscopic surgical route, obtained by removal of tuberculum sellae and planum sphenoidale, offers direct midline access to the retrochiasmatic space and provides excellent visualization of the undersurface of the optic chiasm. In this report, we describe the technical details of the extended endoscopic approach, and review our results using this approach in the surgical management of retrochiasmatic craniopharyngiomas. Methods: Fifteen children, including 9 girls and 6 boys, aged 8 to 15 years underwent surgery using extended endoscopic transsphenoidal approach between 2008 and 2014. Nine patients had a surgical procedure done previously and presented with recurrence of symptoms and regrowth of their residual tumors. Results: A gross total or near total excision was achieved in 10 (66.7% patients, subtotal resection in 4 (26.7%, and partial removal in 1 (6.7% patient. Postoperatively, headache improved in 93.3%, vision recovered in 77.3%, and the hormonal levels stabilised in 66.6%. Three patients (20% developed postoperative CSF leaks which were managed conservatively. Three (20% patients with diabetes insipidus and 2 (13.3% with panhypopituitarism required long-term hormonal replacement therapy. Conclusions: Our early experience suggests that the extended endonasal endoscopic approach is a reasonable option for removal of the retrochiasmal craniopharyngiomas. Compared to other surgical approaches, it provides better opportunities for greater tumor removal and visual improvement without any increase in risks.

  6. Early Results Show Reduced Infection Rate Using No-touch Technique for Expander/ADM Breast Reconstruction

    Directory of Open Access Journals (Sweden)

    Henry B. Wilson, MD, FACS

    2015-03-01

    Full Text Available Summary: Infection is a common complication of immediate breast reconstruction that often leads to device removal, a result emotionally devastating to the patient and frustrating for her surgeon. “No-touch” techniques have been used in other surgical disciplines and plastic surgery, but they have not been reported for breast reconstruction with tissue expanders or implants and acellular dermis. We report a novel technique of tissue expander and acellular dermis placement using no-touch principles with a self-retaining retractor system that holds promise to decrease infectious complications of breast reconstruction.

  7. Seed dispersal into wetlands: Techniques and results for a restored tidal freshwater marsh

    Science.gov (United States)

    Neff, K.P.; Baldwin, A.H.

    2005-01-01

    Although seed dispersal is assumed to be a major factor determining plant community development in restored wetlands, little research exists on density and species richness of seed available through dispersal in these systems. We measured composition and seed dispersal rates at a restored tidal freshwater marsh in Washington, DC, USA by collecting seed dispersing through water and wind. Seed dispersal by water was measured using two methods of seed collection: (1) stationary traps composed of coconut fiber mat along an elevation gradient bracketing the tidal range and (2) a floating surface trawl net attached to a boat. To estimate wind dispersal rates, we collected seed from stationary traps composed of coconut fiber mat positioned above marsh vegetation. We also collected a small number of samples of debris deposited along high tide lines (drift lines) and feces of Canada Goose to explore their seed content. We used the seedling emergence method to determine seed density in all samples, which involved placing the fiber mats or sample material on top of potting soil in a greenhouse misting room and enumerating emerging seedlings. Seedlings from a total of 125 plant species emerged during this study (including 82 in river trawls, 89 in stationary water traps, 21 in drift lines, 39 in wind traps, and 10 in goose feces). The most abundant taxa included Bidens frondosa, Boehmeria cylindrica, Cyperus spp., Eclipta prostrata, and Ludwigia palustris. Total seedling density was significantly greater for the stationary water traps (212 + 30.6 seeds/m2/month) than the equal-sized stationary wind traps (18 + 6.0 seeds/m(2)/month). Lower-bound estimates of total species richness based on the non-parametric Chao 2 asymptotic estimators were greater for seeds in water (106 + 1.4 for stationary water traps and 104 + 5.5 for trawl samples) than for wind (54 + 6.4). Our results indicate that water is the primary source of seeds dispersing to the site and that a species-rich pool

  8. THERMODYNAMIC SPECTRUM OF SOLAR FLARES BASED ON SDO/EVE OBSERVATIONS: TECHNIQUES AND FIRST RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yuming; Zhou, Zhenjun; Liu, Kai; Liu, Rui; Shen, Chenglong [CAS Key Laboratory of Geospace Environment, Department of Geophysics and Planetary Sciences, University of Science and Technology of China, Hefei, Anhui 230026 (China); Zhang, Jie [School of Physics, Astronomy and Computational Sciences, George Mason University, 4400 University Drive, MSN 6A2, Fairfax, VA 22030 (United States); Chamberlin, Phillip C., E-mail: ymwang@ustc.edu.cn [Solar Physics Laboratory, Heliophysics Division, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2016-03-15

    The Solar Dynamics Observatory (SDO)/EUV Variability Experiment (EVE) provides rich information on the thermodynamic processes of solar activities, particularly on solar flares. Here, we develop a method to construct thermodynamic spectrum (TDS) charts based on the EVE spectral lines. This tool could potentially be useful for extreme ultraviolet (EUV) astronomy to learn about the eruptive activities on distant astronomical objects. Through several cases, we illustrate what we can learn from the TDS charts. Furthermore, we apply the TDS method to 74 flares equal to or greater than the M5.0 class, and reach the following statistical results. First, EUV peaks are always behind the soft X-ray (SXR) peaks and stronger flares tend to have faster cooling rates. There is a power-law correlation between the peak delay times and the cooling rates, suggesting a coherent cooling process of flares from SXR to EUV emissions. Second, there are two distinct temperature drift patterns, called Type I and Type II. For Type I flares, the enhanced emission drifts from high to low temperature like a quadrilateral, whereas for Type II flares the drift pattern looks like a triangle. Statistical analysis suggests that Type II flares are more impulsive than Type I flares. Third, for late-phase flares, the peak intensity ratio of the late phase to the main phase is roughly correlated with the flare class, and the flares with a strong late phase are all confined. We believe that the re-deposition of the energy carried by a flux rope, which unsuccessfully erupts out, into thermal emissions is responsible for the strong late phase found in a confined flare. Furthermore, we show the signatures of the flare thermodynamic process in the chromosphere and transition region in the TDS charts. These results provide new clues to advance our understanding of the thermodynamic processes of solar flares and associated solar eruptions, e.g., coronal mass ejections.

  9. Biomechanical caracterisation of lumbar belt by full-field techniques: Preliminary results

    CERN Document Server

    Bonnaire, Rebecca; Calmels, Paul; Convert, Reynald

    2013-01-01

    In France, 50% of the population per year is suffering from low back pain. Lumbar belt are frequently proposed as a part of the treatment of this pathology. However mechanical ways of working of this medical device is not clearly understood, but abdominal pressure is often related. So an optical method was developed in this study to measure strain in lumbar belt and trunk interface and to derive a pressure estimation. Optical method consisted of coupling fringe projection and digital image correlation (DIC). Measurement has been carried out on the right side of a manikin wearing a lumbar belt. Average strain is 0.2 and average pressure is 1 kPa. Continuation of this study will be comparison of strain and pressure in different areas of lumbar belt (left side, front and back) and comparison of different lumbar belts. Results will be used in a finite elements model to determine lumbar belt impact in intern body. In long term, this kind of study will be done on human.

  10. A surgical rat model of sleeve gastrectomy with staple technique: long-term weight loss results.

    Science.gov (United States)

    Patrikakos, Panagiotis; Toutouzas, Konstantinos G; Perrea, Despoina; Menenakos, Evangelos; Pantopoulou, Alkistis; Thomopoulos, Theodore; Papadopoulos, Stefanos; Bramis, John I

    2009-11-01

    Sleeve gastrectomy (SG) is one of the surgical procedures applied for treating morbid obesity consisting of removing the gastric fundus and transforming the stomach into a narrow gastric tube. The aim of this experimental study is to create a functional model of SG and to present the long-term weight loss results. Twenty adult Wistar rats were fed with high fat diet for 12 weeks before being divided randomly in two groups of ten rats each. One group underwent SG performed with the use of staples, and the other group underwent a sham operation (control group). The animals' weight was evaluated weekly for 15 weeks after the operation. All animals survived throughout the experiment. After the operation both groups started to lose weight with maximum weight loss on the seventh postoperative day (POD) for the sham-operated group and on the 15th POD for the SG group. Thereafter, both groups started to regain weight but with different rates. By the fourth postoperative week (POW), the average weight of the sham group did not differ statistically significantly compared to the preoperative weight, while after the eighth POW, rats' average weight was statistically significantly increased compared to the preoperative value. On the other hand, average weight of the SG group was lower postoperatively until the end of the study compared to the preoperative average weight. We have created a surgical rat model of experimental SG model, enabling the further study of biochemical and hormonal parameters.

  11. Ultrasound-guided endocavitary drainage of pelvic abscesses: Technique, results and complications

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, R.S.; McGrath, F P.; Haslam, P.J.; Varghese, J.C.; Lee, M.J

    2003-01-01

    AIM: To evaluate the experience in our institution with ultrasound-guided transrectal and transvaginal (endocavitary) drainage of pelvic abscesses. MATERIALS AND METHODS: Eighteen patients (four male, 14 female; mean age 55 years, range 30-78 years) presenting with pelvic abscesses were referred to our institution for therapeutic drainage over a 4 year period. Patients received broad-spectrum antibiotics prior to drainage, which was performed by either the transvaginal or transrectal route under ultrasound guidance. Patients were given sedo-analgesia in the form of midazolam and fentanyl and local anaesthesia was also employed. Eight French catheters were inserted into the abscess cavities, and patients were subsequently monitored on a daily basis by a member of the interventional radiology team until such time as it was deemed appropriate to remove the catheter. RESULTS: Eighteen catheters were placed in 17 patients, and transvaginal aspiration alone was performed in one patient. Drainage was successful in 16 of 17 patients, but a transgluteal approach was ultimately required in the remaining patient to enable passage of a larger catheter into an infected haematoma. The mean duration of drainage was 5 days, mean time to defervesce 2 days. Spontaneous catheter dislodgement occurred in four patients associated with straining, but this did not have any adverse effect in three of the four patients. CONCLUSION: Endocavitary drainage is an effective method of treatment for pelvic abscesses. Spontaneous catheter dislodgement does not affect patient outcome.

  12. Medial release and lateral imbrication for intractable anterior knee pain: diagnostic process, technique, and results

    Directory of Open Access Journals (Sweden)

    Meldrum AR

    2015-01-01

    Full Text Available Alexander R Meldrum,1 Jeremy R Reed,2 Megan D Dash3 1Department of Surgery, Section of Orthopedic Surgery, University of Calgary, Calgary, AB, Canada; 2Department of Surgery, University of Saskatchewan College of Medicine, Regina, SK, Canada; 3Department of Family Medicine, College of Medicine, University of Saskatchewan, Regina, SK, Canada Purpose: To present two cases of intractable patellofemoral pain syndrome treated with a novel procedure, arthroscopic medial release, and lateral imbrication of the patellar retinaculum. Patients and methods: This case series presents the treatment of three knees in two patients (one bilateral in whom an all-inside arthroscopic medial release and lateral imbrication of the patellar retinaculum was performed. Subjective measurement of pain was the primary outcome measurement, and subjective patellofemoral instability was the secondary outcome measurement. Results: Subjectively the two patients had full resolution of their pain, without any patellofemoral instability. Conclusion: Medial release and lateral imbrication of the patellar retinaculum is a new surgical procedure that has been used in the treatment of intractable patellofemoral pain syndrome. This is the first report of its kind in the literature. While outcome measurements were less than ideal, the patients had positive outcomes, both functionally and in terms of pain. Keywords: anterior knee pain syndrome, chondromalacia patellae, runners knee, patellar chondropathy, patellofemoral dysfunction, patellofemoral tracking disorder

  13. Iterative reconstruction techniques for computed tomography part 2: initial results in dose reduction and image quality

    Energy Technology Data Exchange (ETDEWEB)

    Willemink, Martin J.; Leiner, Tim; Jong, Pim A. de; Nievelstein, Rutger A.J.; Schilham, Arnold M.R. [Utrecht University Medical Center, Department of Radiology, P.O. Box 85500, Utrecht (Netherlands); Heer, Linda M. de [Cardiothoracic Surgery, Utrecht (Netherlands); Budde, Ricardo P.J. [Utrecht University Medical Center, Department of Radiology, P.O. Box 85500, Utrecht (Netherlands); Gelre Hospital, Department of Radiology, Apeldoorn (Netherlands)

    2013-06-15

    To present the results of a systematic literature search aimed at determining to what extent the radiation dose can be reduced with iterative reconstruction (IR) for cardiopulmonary and body imaging with computed tomography (CT) in the clinical setting and what the effects on image quality are with IR versus filtered back-projection (FBP) and to provide recommendations for future research on IR. We searched Medline and Embase from January 2006 to January 2012 and included original research papers concerning IR for CT. The systematic search yielded 380 articles. Forty-nine relevant studies were included. These studies concerned: the chest(n = 26), abdomen(n = 16), both chest and abdomen(n = 1), head(n = 4), spine(n = 1), and no specific area (n = 1). IR reduced noise and artefacts, and it improved subjective and objective image quality compared to FBP at the same dose. Conversely, low-dose IR and normal-dose FBP showed similar noise, artefacts, and subjective and objective image quality. Reported dose reductions ranged from 23 to 76 % compared to locally used default FBP settings. However, IR has not yet been investigated for ultra-low-dose acquisitions with clinical diagnosis and accuracy as endpoints. Benefits of IR include improved subjective and objective image quality as well as radiation dose reduction while preserving image quality. Future studies need to address the value of IR in ultra-low-dose CT with clinically relevant endpoints. (orig.)

  14. Use of allogenic (iliac) corticocancellous graft for Le Fort I interpositional defects: technique and results.

    Science.gov (United States)

    Posnick, Jeffrey C; Sami, Ali

    2015-01-01

    We performed a retrospective review of a consecutive series of 50 patients who had undergone Le Fort I with interpositional grafting during a 3-year period. Maxillary repositioning included horizontal advancement and vertical and transverse change to the extent that an interpositional graft was considered necessary. Allogenic (iliac) corticocancellous bone was used in all cases. Each patient underwent analytic model planning to document the maxillary vector change data points. The recorded data served as an indicator of the osteotomy site gaps requiring grafting. Standardized photographs in centric relation at a minimum of 12 months after treatment were analyzed to measure overjet, overbite, midline position, and first molar lateral occlusion. Specific maxillary region wound healing parameters were reviewed. The patients' mean age at surgery was 32 years (range 15 to 60). Analytic model planning clarified that the study patients had an average of 8 mm horizontal advancement, 2 mm vertical lengthening, and 2 mm of transverse expansion. The data confirmed a favorable occlusion at a minimum of 1 year after surgery with maintenance of a normal overjet (49 of 50 patients, 98%), normal overbite (48 of 50 patients, 96%), planned dental midline positioning (45 of 50 patients, 90%), and ideal first molar lateral occlusion (48 of 50 patients, 96%) for most patients. None of the study patients sustained wound healing complications. Also, no cases of postoperative sepsis or viral illness developed. The results of the present study have confirmed that iliac corticocancellous allograft has minimal systemic or recipient site complications and can be safely used to fill complex 3-dimensional interpositional defects associated with Le Fort I osteotomy and/or repositioning. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  15. Difficulties and Problematic Steps in Teaching the Onstep Technique for Inguinal Hernia Repair, Results from a Focus Group Interview

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Laursen, Jannie; Rosenberg, Jacob

    2016-01-01

    Background. When a new surgical technique is brought into a department, it is often experienced surgeons that learn it first and then pass it on to younger surgeons in training. This study seeks to clarify the problems and positive experiences when teaching and training surgeons in the Onstep...... technique for inguinal hernia repair, seen from the instructor's point of view. Methods. We designed a qualitative study using a focus group to allow participants to elaborate freely and facilitate a discussion. Participants were surgeons with extensive experience in performing the Onstep technique from...... Germany, UK, France, Belgium, Italy, Greece, and Sweden. Results. Four main themes were found, with one theme covering three subthemes: instruction of others (experience, patient selection, and tailored teaching), comfort, concerns/fear, and anatomy. Conclusion. Surgeons receiving a one-day training...

  16. Comparison of the cytology technique and the frozen section results in intraoperative consultation of the breast lesions

    Directory of Open Access Journals (Sweden)

    "Haeri H

    2002-07-01

    Full Text Available The cytology study is effective and reliable technique in intraoperative consultation. This study was performed to evaluate the accuracy of the cytology study in intraoperative consultation of the breast lesions. 125 specimens of the breast lesions were examined and studied in Imam Khomeini Hospital during the years 1998-99. The sensitivity, specificity and accuracy for cytological method were 87.5% , 95%, 90.5% and for the frozen section 92.4%, 100% and 95.4% respectively. The false positive reports were 2% in the cytology technique and the most important source of error and false postivie reports was fibroadenoma in this method. By reviewing the results. It could be concluded that combination of these two techniques is beneficial and more reliable in intraoperative consultation resports of the breast lesions

  17. Clinical and Histological Results of Vertical Ridge Augmentation of Atrophic Posterior Mandible with Inlay Technique of Cancellous Equine Bone Blocks

    Directory of Open Access Journals (Sweden)

    Pistilli R

    2013-12-01

    Full Text Available Aim: We want to evaluate a new bone block material in the inlay technique, for the vertical bone augmentation of a posterior atrophic mandible, in order to perfom aesthetic and prosthetic rehabilitation and enable implant insertion. Materials & Methods: Inlay technique and the subsequent successful implant rehabilitation in the atrophic right posterior mandible in a 42-year-old woman, was completed using a cancellous equine bone block as grafting material. Results: Three months after surgical procedure both clinical and histological aspects show complete integration of the biomaterial with the surrounding bone and three dental implants were placed. Computed tomography and conventional radiography showed a 5mm mean vertical bone gain. Conclusion: Cancellous equine bone grafts may be an effective alternative to autogenous bone and/or inorganic bovine bone for reconstruction of the posterior mandible using inlay technique.

  18. Importance of integrated results of different non-destructive techniques in order to evaluate defects in panel paintings: the contribution of infrared, optical and ultrasonic techniques

    Science.gov (United States)

    Sfarra, S.; Theodorakeas, P.; Ibarra-Castanedo, C.; Avdelidis, N. P.; Paoletti, A.; Paoletti, D.; Hrissagis, K.; Bendada, A.; Koui, M.; Maldague, X.

    2011-06-01

    The increasing deterioration of panel paintings can be due to physical processes that take place during exhibition or transit, or as a result of temperature and humidity fluctuations within a building, church or museum. In response to environmental alterations, a panel painting can expand or contract and a new equilibrium state is eventually reached. These adjustments though, are usually accompanied by a change in shape in order to accommodate to the new conditions. In this work, a holographic method for detecting detached regions and micro-cracks is described. Some of these defects are confirmed by Thermographic Signal Reconstruction (TSR) technique. In addition, Pulsed Phase Thermography (PPT) and Principal Component Thermography (PCT) allow to identify with greater contrast two artificial defects in Mylar which are crucial to understand the topic of interest: the discrimination between defect materials. Finally, traditional contact ultrasounds applications, are widely applied for the evaluation of the wood quality in several characterization procedures. Inspecting the specimen from the front side, the natural and artificial defects of the specimen are confirmed. Experimental results derived by the application of the integrated methods on an Italian panel painting reproduction, called The Angel specimen, are presented. The main advantages that these techniques can offer to the conservation and restoration of artworks are emphasized.

  19. Adult spinal deformity treated with minimally invasive surgery. Description of surgical technique, radiological results and literature review.

    Science.gov (United States)

    Domínguez, I; Luque, R; Noriega, M; Rey, J; Alía, J; Urda, A; Marco, F

    2017-09-06

    The prevalence of adult spinal deformity has been increasing exponentially over time. Surgery has been credited with good radiological and clinical results. The incidence of complications is high. MIS techniques provide good results with fewer complications. This is a retrospective study of 25 patients with an adult spinal deformity treated by MIS surgery, with a minimum follow-up of 6 months. Radiological improvement was SVA from 5 to 2cm, coronal Cobb angle from 31° to 6°, and lumbar lordosis from 18° to 38°. All of these parameters remained stable over time. We also present the complications that appeared in 4 patients (16%). Only one patient needed reoperation. We describe the technique used and review the references on the subject. We conclude that the MIS technique for treating adult spinal deformity has comparable results to those of the conventional techniques but with fewer complications. Copyright © 2017 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Preferred tools and techniques for implantation of cardiac electronic devices in Europe: results of the European Heart Rhythm Association survey.

    Science.gov (United States)

    Bongiorni, Maria Grazia; Proclemer, Alessandro; Dobreanu, Dan; Marinskis, Germanas; Pison, Laurent; Blomstrom-Lundqvist, Carina

    2013-11-01

    The aim of this European Heart Rhythm Association (EHRA) survey was to assess clinical practice in relation to the tools and techniques used for cardiac implantable electronic devices procedures in the European countries. Responses to the questionnaire were received from 62 members of the EHRA research network. The survey involved high-, medium-, and low-volume implanting centres, performing, respectively, more than 200, 100-199 and under 100 implants per year. The following topics were explored: the side approach for implantation, surgical techniques for pocket incision, first venous access for lead implantation, preference of lead fixation, preferred coil number for implantable cardioverter-defibrillator (ICD) leads, right ventricular pacing site, generator placement site, subcutaneous ICD implantation, specific tools and techniques for cardiac resynchronization therapy (CRT), lead implantation sequence in CRT, coronary sinus cannulation technique, target site for left ventricular lead placement, strategy in left ventricular lead implant failure, mean CRT implantation time, optimization of the atrioventricular (AV) and ventriculo-ventricular intervals, CRT implants in patients with permanent atrial fibrillation, AV node ablation in patients with permanent AF. This panoramic view allows us to find out the operator preferences regarding the techniques and tools for device implantation in Europe. The results showed different practices in all the fields we investigated, nevertheless the survey also outlines a good adherence to the common standards and recommendations.

  1. Image processing techniques revealing the relationship between the field-measured ambient gamma dose equivalent rate and geological conditions at a granitic area, Velence Mountains, Hungary

    Science.gov (United States)

    Beltran Torres, Silvana; Petrik, Attila; Zsuzsanna Szabó, Katalin; Jordan, Gyozo; Szabó, Csaba

    2017-04-01

    In order to estimate the annual dose that the public receive from natural radioactivity, the identification of the potential risk areas is required which, in turn, necessitates understanding the relationship between the spatial distribution of natural radioactivity and the geogenic risk factors (e.g., rock types, dykes, faults, soil conditions, etc.). A detailed spatial analysis of ambient gamma dose equivalent rate was performed in the western side of Velence Mountains, the largest outcropped granitic area in Hungary. In order to assess the role of local geology in the spatial distribution of ambient gamma dose rates, field measurements were carried out at ground level at 300 sites along a 250 m x 250 m regular grid in a total surface of 14.7 km2. Digital image processing methods were applied to identify anomalies, heterogeneities and spatial patterns in the measured gamma dose rates, including local maxima and minima determination, digital cross sections, gradient magnitude and gradient direction, second derivative profile curvature, local variability, lineament density, 2D autocorrelation and directional variogram analyses. Statistical inference showed that different gamma dose rate levels are associated with the rock types (i.e., Carboniferous granite, Pleistocene colluvial, proluvial, deluvial sediments and talus, and Pannonian sand and pebble), with the highest level on the Carboniferous granite including outlying values. Moreover, digital image processing revealed that linear gamma dose rate spatial features are parallel to the SW-NE dyke system and possibly to the NW-SE main fractures. The results of this study underline the importance of understanding the role of geogenic risk factors influencing the ambient gamma dose rate received by public. The study also demonstrates the power of the image processing techniques for the identification of spatial pattern in field-measured geogenic radiation.

  2. Next-Generation Sequencing Techniques Reveal that Genomic Imprinting Is Absent in Day-Old Gallus gallus domesticus Brains.

    Science.gov (United States)

    Wang, Qiong; Li, Kaiyang; Zhang, Daixi; Li, Junying; Xu, Guiyun; Zheng, Jiangxia; Yang, Ning; Qu, Lujiang

    2015-01-01

    Genomic imprinting is a phenomenon characterized by parent-of-origin-specific gene expression. While widely documented in viviparous mammals and plants, imprinting in oviparous birds remains controversial. Because genomic imprinting is temporal- and tissue-specific, we investigated this phenomenon only in the brain tissues of 1-day-old chickens (Gallus gallus). We used next-generation sequencing technology to compare four transcriptomes pooled from 11 chickens, generated from reciprocally crossed families, to the DNA sequences of their parents. Candidate imprinted genes were then selected from these sequence alignments and subjected to verification experiments that excluded all but one SNP. Subsequent experiments performed with two new sets of reciprocally crossed families resulted in the exclusion of that candidate SNP as well. Attempts to find evidence of genomic imprinting from long non-coding RNAs yielded negative results. We therefore conclude that genomic imprinting is absent in the brains of 1-day-old chickens. However, due to the temporal and tissue specificity of imprinting, our results cannot be extended to all growth stages and tissue types.

  3. Techniques and results

    Digital Repository Service at National Institute of Oceanography (India)

    Mudholkar, A.V.; Pattan, J.N.; Sudhakar, M.

    was carried out to narrow down the area for detailed exploration These studies were done to candidate mine sites in the area of high potential The database to record details was created in the National Institute of Oceanography (NIO), India, Goa and Engineers...

  4. Salivary bacterial fingerprints of established oral disease revealed by the Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) technique

    DEFF Research Database (Denmark)

    Belstrøm, Daniel; Paster, Bruce J; Fiehn, Nils-Erik;

    2016-01-01

    Identification using Next Generation Sequencing) for comparison of the salivary microbiota in patients with periodontitis, patients with dental caries, and orally healthy individuals. The hypothesis was that this method could add on to the existing knowledge on salivary bacterial profiles in oral health...... and disease. DESIGN: Stimulated saliva samples (n=30) were collected from 10 patients with untreated periodontitis, 10 patients with untreated dental caries, and 10 orally healthy individuals. Salivary microbiota was analyzed using HOMINGS and statistical analysis was performed using Kruskal-Wallis test...... with Benjamini-Hochberg's correction. RESULTS: From a total of 30 saliva samples, a mean number of probe targets of 205 (range 120-353) were identified, and a statistically significant higher mean number of targets was registered in samples from patients with periodontitis (mean 220, range 143-306) and dental...

  5. Salivary bacterial fingerprints of established oral disease revealed by the Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) technique

    DEFF Research Database (Denmark)

    Belstrøm, Daniel; Paster, Bruce J; Fiehn, Nils-Erik;

    2016-01-01

    and disease. DESIGN: Stimulated saliva samples (n=30) were collected from 10 patients with untreated periodontitis, 10 patients with untreated dental caries, and 10 orally healthy individuals. Salivary microbiota was analyzed using HOMINGS and statistical analysis was performed using Kruskal-Wallis test...... with Benjamini-Hochberg's correction. RESULTS: From a total of 30 saliva samples, a mean number of probe targets of 205 (range 120-353) were identified, and a statistically significant higher mean number of targets was registered in samples from patients with periodontitis (mean 220, range 143-306) and dental...... Identification using Next Generation Sequencing) for comparison of the salivary microbiota in patients with periodontitis, patients with dental caries, and orally healthy individuals. The hypothesis was that this method could add on to the existing knowledge on salivary bacterial profiles in oral health...

  6. Investigation of condenser deficiencies utilizing state-of-the art test instrumentation and modeling techniques and results from post modification testing

    Energy Technology Data Exchange (ETDEWEB)

    Bell, R.J.; Hardy, C.D. [Heat Exchanger Systems, Inc., Boston, MA (United States)

    1996-05-01

    Higher than design condenser pressure is a major contributor to poor station heat rates and the need to shed load during the summer months. State-of-the art test instrumentation when properly utilized can usually reveal the cause of condenser malperformance. Recent developments in condenser modeling utilizing computational fluids dynamics techniques allow the utility to test various condenser modifications in order to ascertain which modification will result in the greatest decrease in condenser pressure. This paper describes the condenser test instrumentation recently installed in a large mid-western fossil station to diagnose the cause of high condenser pressure. The paper also presents analyzed data results identifying both the cause and magnitude of the performance deficiency. Results of CFD modeling are presented demonstrating what corrective modifications appear the most promising.

  7. Multistage bioassociation of uranium onto an extremely halophilic archaeon revealed by a unique combination of spectroscopic and microscopic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Bader, Miriam; Müller, Katharina; Foerstendorf, Harald; Drobot, Björn [Helmholtz-Zentrum Dresden – Rossendorf, Institute of Resource Ecology, Bautzner Landstraße 400, 01328 Dresden (Germany); Schmidt, Matthias; Musat, Niculina [Helmholtz Centre for Environmental Research–UFZ, Department of Isotope Biogeochemistry, Permoserstraße 15, 04318 Leipzig (Germany); Swanson, Juliet S.; Reed, Donald T. [Los Alamos National Laboratory, Repository Science and Operations, 1400 University Drive, Carlsbad, NM, 88220 (United States); Stumpf, Thorsten [Helmholtz-Zentrum Dresden – Rossendorf, Institute of Resource Ecology, Bautzner Landstraße 400, 01328 Dresden (Germany); Cherkouk, Andrea, E-mail: a.cherkouk@hzdr.de [Helmholtz-Zentrum Dresden – Rossendorf, Institute of Resource Ecology, Bautzner Landstraße 400, 01328 Dresden (Germany)

    2017-04-05

    Highlights: • First prolonged kinetics study of uranium to halophilic archaea was performed. • An atypical time-dependent bioassociation behavior of uranium was observed. • Unique combination of spectroscopic and microscopic methods was used. • In situ ATR FT-IR showed association of U(VI) to phosphoryl and carboxylate groups. • Time-dependent changes of U(VI) localization could be monitored by SEM/EDX. - Abstract: The interactions of two extremely halophilic archaea with uranium were investigated at high ionic strength as a function of time, pH and uranium concentration. Halobacterium noricense DSM-15987 and Halobacterium sp. putatively noricense, isolated from the Waste Isolation Pilot Plant repository, were used for these investigations. The kinetics of U(VI) bioassociation with both strains showed an atypical multistage behavior, meaning that after an initial phase of U(VI) sorption, an unexpected interim period of U(VI) release was observed, followed by a slow reassociation of uranium with the cells. By applying in situ attenuated total reflection Fourier-transform infrared spectroscopy, the involvement of phosphoryl and carboxylate groups in U(VI) complexation during the first biosorption phase was shown. Differences in cell morphology and uranium localization become visible at different stages of the bioassociation process, as shown with scanning electron microscopy in combination with energy dispersive X-ray spectroscopy. Our results demonstrate for the first time that association of uranium with the extremely halophilic archaeon is a multistage process, beginning with sorption and followed by another process, probably biomineralization.

  8. Results of a bone splint technique for the treatment of lower limb deformities in children with type I osteogenesis imperfecta

    Directory of Open Access Journals (Sweden)

    Dasheng Lin

    2013-01-01

    Full Text Available Background: Children with osteogenesis imperfecta (OI can suffer from frequent fractures and limb deformities, resulting in impaired ambulation. Osteopenia and thin cortices complicate orthopedic treatment in this group. This study evaluates the clinical results of a bone splint technique for the treatment of lower limb deformities in children with type I OI. The technique consists of internal plating combined with cortical strut allograft fixation. Materials and Methods: We prospectively followed nine children (five boys, four girls with lower limb deformities due to type I OI, who had been treated with the bone splint technique (11 femurs, four tibias between 2003 and 2006. The fracture healing time, deformity improvement, ambulation ability and complications were recorded to evaluate treatment effects. Results: At the time of surgery the average age in our study was 7.7 years (range 5-12 years. The average length of followup was 69 months (range 60-84 months. All patients had good fracture healing with an average healing time of 14 weeks (range 12-16 weeks and none experienced further fractures, deformity, or nonunion. The fixation remained stable throughout the procedure in all cases, with no evidence of loosening or breakage of screws and the deformity and mobility significantly improved after surgery. Of the two children confined to bed before surgery, one was able to walk on crutches and the other needed a wheelchair. The other seven patients could walk without walking aids or support like crutches. Conclusions: These findings suggest that the bone splint technique provides good mechanical support and increases the bone mass. It is an effective treatment for children with OI and lower limb deformities.

  9. Reconstruction of a deficient patella in revision total knee arthroplasty: results of a new surgical technique using transcortical wiring.

    Science.gov (United States)

    Seo, Jai-Gon; Moon, Young-Wan; Lee, Byung-Hoon; Kim, Sang-Min

    2015-02-01

    This study aimed to report the results of a novel surgical technique for the reconstruction of a deficient patella during revision total knee arthroplasty (TKA). Twenty-eight patients (30 knees) with a deficient patella were treated with an onlay-type prosthesis and bone-augmenting procedure, using acrylic bone cement and transcortical wiring. The technique was indicated when the thickness of remnant patella was less than 8mm with variable amounts of the peripheral rim. Mean follow-up period was 36.6months (range, 24 to 55months).The respective mean Knee Society scores for knee and function improved from 34.2 and 23 points, preoperatively to 73.5 and 61 points, at final follow-up. One patient experienced patellar fracture 1week after surgery. There were no complications associated with implanted hardware. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Comparative study on the treatment of Rockwood type III acute acromioclavicular dislocation: Clinical results from the TightRope(®) technique vs. K-wire fixation.

    Science.gov (United States)

    Horst, K; Garving, C; Thometzki, T; Lichte, P; Knobe, M; Dienstknecht, T; Hofman, M; Pape, H-C

    2017-04-01

    The aim of this study was to address the inconsistency regarding the operative treatment of Rockwood type III acromioclavicular joint separation. We compared results after single- and double TightRope(®) reduction with results after acromioclavicular transfixation via K-wires only and additional ligament augmentation in acute acromioclavicular (AC) joint separations graded Rockwood type III, and hypothesized that the TightRope(®) technique leads to better clinical and radiological results. We conducted a retrospective clinical cohort study and included 42 consecutive patients (mean age 43 years [24-66]) diagnosed and operatively treated between 2004 and 2012 (mean follow-up was 54.6 months [15-118]). Specific shoulder scores as well as scores reflecting the patients' overall mental and physical health status were used. Radiological evaluation was also performed. The SF12 test revealed comparability between all subgroups. Specific shoulder tests and a visual analogue scale demonstrated comparable results. Radiographic measurements showed a significant reduction in the AC distance and CC distance after surgery in all subgroups. The early complication rate was 9.5% for all patients, while late complications occurred in 14.3% of all cases. Compared to the established methods, the operative TightRope(®) procedures represent a safe alternative in Rockwood III injuries. All investigated techniques predominantly led to good and excellent clinical results in acute Rockwood type III AC joint instabilities. Avoidance of material removal and shorter hospital stays appear to speak in favour for the TightRope(®) technique. IV. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  11. Preliminary results from osteosynthesis using Ender nails by means of a percutaneous technique, in humeral diaphysis fractures in adults☆

    Science.gov (United States)

    Godinho, Glaydson Gomes; França, Flávio de Oliveira; Freitas, José Márcio Alves; Santos, Flávio Márcio Lago; Correa, Guilherme de Almeida Sellos; Maia, Lucas Russo

    2015-01-01

    Objective To demonstrate the clinical and functional results from treatment of humeral diaphysis fractures using Ender nails. Methods Eighteen patients who underwent osteosynthesis of humeral diaphysis fractures using Ender nails were evaluated. In addition to the clinical and radiographic evaluations, patients with a minimum of one year of follow-up were assessed by means of the Constant, American Shoulder and Elbow Surgeons (ASES), Mayo Clinic and Simple Shoulder Value (SSV) functional scores, and in relation to the degree of satisfaction with the final result. The fixation technique used was by means of an anterograde percutaneous route. Results All the patients achieved fracture consolidation, after a mean of 2.9 months (ranging from 2 to 4 months). The mean Constant score was 85.7 (ranging from 54 to 100) and the mean ASES score was 95.9 (ranging from 76 to 100). All the patients achieved the maximum score on the Mayo Clinic scale. Conclusion Fixation of humeral diaphysis fractures using Ender nails by means of a percutaneous technique was shown to be a method with promising preliminary results. PMID:26417566

  12. A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

    Directory of Open Access Journals (Sweden)

    Claas Wodarczyk

    Full Text Available Polycystin-1 (PC-1, the product of the PKD1 gene, mutated in the majority of cases of Autosomal Dominant Polycystic Kidney Disease (ADPKD, is a very large (approximately 520 kDa plasma membrane receptor localized in several subcellular compartments including cell-cell/matrix junctions as well as cilia. While heterologous over-expression systems have allowed identification of several of the potential biological roles of this receptor, its precise function remains largely elusive. Studying PC-1 in vivo has been a challenging task due to its complexity and low expression levels. To overcome these limitations and facilitate the study of endogenous PC-1, we have inserted HA- or Myc-tag sequences into the Pkd1 locus by homologous recombination. Here, we show that our approach was successful in generating a fully functional and easily detectable endogenous PC-1. Characterization of PC-1 distribution in vivo showed that it is expressed ubiquitously and is developmentally-regulated in most tissues. Furthermore, our novel tool allowed us to investigate the role of PC-1 in brain, where the protein is abundantly expressed. Subcellular localization of PC-1 revealed strong and specific staining in ciliated ependymal and choroid plexus cells. Consistent with this distribution, we observed hydrocephalus formation both in the ubiquitous knock-out embryos and in newborn mice with conditional inactivation of the Pkd1 gene in the brain. Both choroid plexus and ependymal cilia were morphologically normal in these mice, suggesting a role for PC-1 in ciliary function or signalling in this compartment, rather than in ciliogenesis. We propose that the role of PC-1 in the brain cilia might be to prevent hydrocephalus, a previously unrecognized role for this receptor and one that might have important implications for other genetic or sporadic diseases.

  13. Comparison of three different insertion techniques with LMA-UniqueTM in adults: results of a randomized trial

    Directory of Open Access Journals (Sweden)

    Merih Eglen

    Full Text Available Abstract Background The triple airway maneuver insertion technique allowed faster insertion of the LMA. This study compared three different insertion techniques of the laryngeal mask airway-UniqueTM. Methods One hundred and eighty ASA I-II patients aged 18-65 years were included into the study. Patients were randomly allocated to the standard, rotational and triple airway maneuver (triple group. In the standard group (n = 60, the LMA (Laryngeal Mask Airway was inserted with digital intraoral manipulation. In the triple group (n = 60, the LMA was inserted with triple airway maneuver (mouth opening, head extension and jaw thrust. In the rotational group (n = 60, LMA was inserted back-to-front, like a Guedel airway. Successful insertion at first attempt, time for successful insertion, fiber optic assessment, airway morbidity and hemodynamic responses were assessed. Results Successful insertion at the first attempt was 88.3% for the standard, 78.3% for the rotational and 88.3% for the triple group. Overall success rate (defined as successful insertion at first and second attempt was 93% for the standard, 90% for the rotational and 95% for the triple group. Time for successful insertion was significantly shorter in the triple group (mean [range] 8.63 [5-19]s compared with the standard (11.78 [6-24]s and rotational group (11.57 [5-31]s. Fiber optic assessment, airway morbidity and hemodynamic responses were similar in all groups. Conclusions Rotational and triple airway maneuver insertion techniques are acceptable alternatives. Triple airway maneuver technique shows higher overall success rates and allows shorter insertion time for LMA insertion and should therefore be kept in mind for emergent situations.

  14. First results on a process-oriented rain area classification technique using Meteosat Second Generation SEVIRI nighttime data

    Directory of Open Access Journals (Sweden)

    B. Thies

    2008-04-01

    Full Text Available A new technique for process-oriented rain area classification using Meteosat Second Generation SEVIRI nighttime data is introduced. It is based on a combination of the Advective Convective Technique (ACT which focuses on precipitation areas connected to convective processes and the Rain Area Delineation Scheme during Nighttime (RADS-N a new technique for the improved detection of stratiform precipitation areas (e.g. in connection with mid-latitude frontal systems. The ACT which uses positive brightness temperature differences between the water vapour (WV and the infrared (IR channels (ΔTWV-IR for the detection of convective clouds and connected precipitating clouds has been transferred from Meteosat First Generation (MFG Metesoat Visible and Infra-Red Imager radiometer (MVIRI to Meteosat Second Generation (MSG Spinning Enhanced Visible and InfraRed Imager (SEVIRI. RADS-N is based on the new conceptual model that precipitating cloud areas are characterised by a large cloud water path (cwp and the presence of ice particles in the upper part of the cloud. The technique considers information about both parameters inherent in the channel differences ΔT3.9-10.8, ΔT3.9-7.3, ΔT8.7-10.8, and ΔT10.8-12.1, to detect potentially precipitating cloud areas. All four channel differences are used to gain implicit knowledge about the cwp. ΔT8.7-10.8 and ΔT10.8-12.1 are additionally considered to gain information about the cloud phase. First results of a comparison study between the classified rain areas and corresponding ground based radar data for precipitation events in connection with a cold front occlusion show encouraging performance of the new proposed process-oriented rain area classification scheme.

  15. [Late results of the "simplified technique" in the surgical management of a thoracoabdominal aortic aneurysm, ten years later - clinical report].

    Science.gov (United States)

    Dinis da Gama, A

    2007-01-01

    The authors report the clinical case of a dissecting thoracoabdominal aortic aneurysm, in a 49-years old female, with the diagnosis of Marfan's syndrome, who underwent surgical treatment utilizing the "simplified technique", introduced by ourselves in 1983, for the management of this most demanding situation. Reviewed ten years later, having reassumed her social and professional life, a control angio-CT disclosed the procedure of aortic reconstruction and the revascularization of the digestive and renal arteries working in excellent condition. The unique and singular reconstructive procedure here utilized and its excellent long term result, justify its presentation and divulgation.

  16. The role of disease perceptions and results sharing in psychological adaptation after genetic susceptibility testing: the REVEAL Study.

    Science.gov (United States)

    Ashida, Sato; Koehly, Laura M; Roberts, J Scott; Chen, Clara A; Hiraki, Susan; Green, Robert C

    2010-12-01

    This study evaluates the extent to which psychological adaptation (validated measures of depressive symptoms, anxiety, and test-specific distress) after genetic susceptibility testing is influenced by changes in beliefs about Alzheimer's disease (AD) and sharing of test results with others. Adult children of AD patients (N=269) from a randomized clinical trial involving genetic testing for apolipoprotein E (APOE) provided information before, as well as 6 weeks and 12 months after results disclosure. The levels of adaptation varied highly among participants at 12-month assessment. Participants who learned that they were ε4 negative (lower risk) had a reduction in perceived risk and concern about developing AD compared with those who learned that they were ε4 positive. Those who received results through an extended educational protocol (three in-person visits) had a larger decline in AD concern than those in a condensed protocol (educational brochure and two in-person visits). Increase in AD concern 6 weeks after disclosure was associated with increase in depression scores (b=0.20, Ptesting (b=0.18, P=0.02) 1 year after testing. Increase in perceived risk (b=0.16, P=0.04) was also associated with higher AD genetic testing distress. Sharing the test results with health professionals and friends (but not family) was associated with decrease in depression (b=-0.11, P=0.05) and anxiety levels (b=-0.16, Ptesting may help facilitate test recipients' long-term psychological adaptation.

  17. Comparison of Surgical Blade and Cryosurgery with Liquid Nitrogen Techniques in Treatment of Physiologic Gingival Pigmentation: Short Term Results

    Directory of Open Access Journals (Sweden)

    Saeed Rahmati

    2014-12-01

    Full Text Available Statement of the Problem: Melanin pigmentation of the gingiva is a crucial esthetic problem. A variety of methods have been used for gingival depigmentation. Purpose: The purpose of this study was to compare the results of two treatment modalities: scalpel technique and cryotherapy with liquid nitrogen in treatment of gingival pigmentation. Materials and Method: Twenty patients with chief complaint of gingival pigmentation participated in our study. 10 patients were treated with cryotherapy and remaining 10 participants were undergone the scalpel technique surgery. We evaluated acquiescence and comfort of the patients, degree of depigmentation, based on the area of pigmentation shown by gridlines option in Microsoft Paint software, and the presence or absence of gingival recession before and one month after treatment. Data was analyzed using Mann-Whitney and Chi-Square tests. A significance level of p≤ 0.05 was adopted. Results: Mean value and standard deviation of depigmentation for group A and group B was 96.17±2.51 and 95±2.48, respectively. The difference was not statistically significant (p= 0.225. There was no association between the treatment modality and the gingival recession (p= 0.303 or the treatment modality and the patient satisfaction (p= 0.346. No significant difference was found between gingival recession measures before and after the operation in the two treatment modalities. Conclusion: Surgical blade and cryosurgery with liquid nitrogen had no significant difference in treatment of physiologic gingival pigmentation. Both Techniques are acceptable in the treatment of gingival pigmentation.

  18. Techniques for the manufacturing of stiff and lightweight optical mirror panels based on slumping of glass sheets: concepts and results

    Science.gov (United States)

    Canestrari, R.; Ghigo, M.; Pareschi, G.; Basso, S.; Motta, G.; Doro, M.; Giro, E.; Lessio, L.

    2009-08-01

    In the last decade Very High Energy (VHE) gamma-ray astronomy has improved rapidly opening a new window for ground-based astronomy with surprising implications in the theoretical models. Nowadays, it is possible to make imaging, photometry and spectroscopy of sources with good sensitivity and angular resolution using new facilities as MAGIC, HESS and VERITAS. The latest results of astronomy in the TeV band obtained using such facilities demonstrate the essential role of this window for high energy astrophysics. For this reason new projects (e.g. CTA and AGIS) have been started with the aim to increase the sensitivity and expand the energy band coverage. For such telescopes arrays probably tens of thousands of optical mirror panels must be manufactured with an adequate industrial process, then tested and mounted into the telescopes. Because of the high number of mirrors it is mandatory to perform feasibility studies to test various techniques to meet the technical and cost-effectiveness requirements for the next generation TeV telescopes as CTA and AGIS. In this context at the Astronomical Observatory of Brera (INAF-OAB) we have started the investigation of different techniques for the manufacturing of stiff and lightweight optical glass mirror panels. These panels show a sandwich-like structure with two thin glass skins on both sides, the reflective one being optically shaped using an ad-hoc slumping procedure. The technologies here presented can be addressed both for primary or secondary mirrors for the next generation of Cherenkov telescopes. In this paper we present and discuss the different techniques we are investigating with some preliminary results obtained from test panels realized.

  19. Computational Analysis Reveals the Association of Threonine 118 Methionine Mutation in PMP22 Resulting in CMT-1A

    Directory of Open Access Journals (Sweden)

    Chundi Vinay Kumar

    2014-01-01

    Full Text Available The T118M mutation in PMP22 gene is associated with Charcot Marie Tooth, type 1A (CMT1A. CMT1A is a form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Mutations in CMT related disorder are seen to increase the stability of the protein resulting in the diseased state. We performed SNP analysis for all the nsSNPs of PMP22 protein and carried out molecular dynamics simulation for T118M mutation to compare the stability difference between the wild type protein structure and the mutant protein structure. The mutation T118M resulted in the overall increase in the stability of the mutant protein. The superimposed structure shows marked structural variation between the wild type and the mutant protein structures.

  20. Endovascular techniques for the treatment of ruptured abdominal aortic aneurysms: 7-year intention-to-treat results.

    Science.gov (United States)

    Dalainas, Ilias; Nano, Giovanni; Bianchi, Paolo; Stegher, Silvia; Casana, Renato; Malacrida, Giovanni; Tealdi, Domenico G

    2006-10-01

    The purpose of this single-institution study was to describe our 7-year intention-to-treat results, obtained with the use of endovascular techniques for the treatment of ruptured abdominal aortic aneurysms (rAAA). From October 1998 until March 2005, a total of 28 patients were admitted or transferred to our department with an rAAA. They were all treated according to a management protocol of intention-to-treat with endovascular techniques. Twenty of the patients received endovascular treatment and the remaining 8 underwent an open surgery procedure. The mortality rate of the endovascularly treated patients was 40% (8 in 20), whereas of the 8 surgical patients 3 survived (mortality = 62.5%). The overall mortality rate of the 28 patients admitted with an rAAA was 46.4% (13 of 28 patients). In our experience the intension-to-treat protocol for rAAA offered acceptable results in terms of mortality rates. Multi-center studies are necessary to establish the role of endovascular treatment in patients with rAAA.

  1. Clinical features, cytology and bacterial culture results in dogs with and without cheilitis and comparison of three sampling techniques.

    Science.gov (United States)

    Doelle, Maren; Loeffler, Anette; Wolf, Katharina; Kostka, Veit; Linek, Monika

    2016-06-01

    Cheilitis is a common presentation in dogs associated with a variety of skin diseases and often complicated by microbial infections. To describe and compare clinical and cytological features and bacterial culture results from the lower lips of dogs with cheilitis (as compared to healthy controls), and to evaluate three cytology sampling techniques for their abilities to differentiate between the groups. Fifty six dogs with cheilitis and 54 controls. Anatomy and clinical signs of the lower lip were recorded. Cytology samples taken by tape strip, direct impression and swabs rolled over skin were scored semiquantitatively for microorganisms, inflammatory cells and keratinocytes. Cytology scores were correlated with semiquantitative bacterial culture scores. Pure breeds, frequency of lip folds and all cytology scores except keratinocytes were higher in dogs with cheilitis than in controls, but a substantial overlap was seen in all microorganisms between the groups. Hypersensitivity disorders were diagnosed in 40 of 56 dogs with cheilitis. The tape strip technique yielded the greatest differences between groups. Bacterial growth was reported in 100% of dogs with cheilitis and in 93% of the controls. Pathogens such as Staphylococcus pseudintermedius, Escherichia coli and Pseudomonas spp were found more frequently in dogs with cheilitis. Cytology and bacterial culture were poorly correlated. Cheilitis was associated with primary hypersensitivity disorders and the presence of a lip fold was a predisposing factor. Results of aerobic culture were similar to prior studies on pyoderma of other body sites, except for higher rates of Pseudomonas spp. isolation. © 2016 ESVD and ACVD.

  2. Long-term results of the surgical treatment of Peyronie's disease with Egydio's technique: a European multicentre study

    Institute of Scientific and Technical Information of China (English)

    Salvatore Sansalone; Giulio Garaffa; Rados Djinovic; Stefano Pecoraro; Mauro Silvanis; Guido Barbagli; Alessandro Zucchi; Giuseppe Vespasiani; Carla Loreto8

    2011-01-01

    The long-term outcomes of 157 patients affected by Peyronie's disease (PD) who underwent penile straightening with Egydio's technique between January 2004 and December 2008 are reported.Only patients with PD who were stable for at least 6-12 months prior to surgery were enrolled in this study.Preoperative assessment included a dynamic echo colour Doppler ultrasound scan to evaluate the degree of penile deformity and the peak systolic velocity in the cavernosal arteries and an assessment of erectile function with the administration of the International Index of Erectile Function 5 (11EF-5) questionnaire.Stretched penile length was recorded pre-and postoperatively.Surgical complications,cosmesis and sexual function,patient satisfaction and postoperative erectile function were assessed postoperatively at 3 months,i year and 2 years,respectively.After a median follow-up period of 20 months (range:12-24 months),we found that mild residual curvature (12%) and glans hypoesthesia (3%) were the only causes of partial dissatisfaction.No rejection of the graft was observed.All patients recovered their ability to penetrate with no difficulty.In addition,an intraoperative average increase of 2.5 cm (range:1.7-4.1 cm) in stretched penile length was recorded,with all patients engaging in penetrative sexual intercourse.In conclusion,this procedure represents a safe and reproducible technique for the correction of penile curvature resulting from PD and yields excellent cosmetic and functional results.

  3. DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

    Directory of Open Access Journals (Sweden)

    Raajit Rampal

    2014-12-01

    Full Text Available Somatic mutations in IDH1/IDH2 and TET2 result in impaired TET2-mediated conversion of 5-methylcytosine (5mC to 5-hydroxymethylcytosine (5hmC. The observation that WT1 inactivating mutations anticorrelate with TET2/IDH1/IDH2 mutations in acute myeloid leukemia (AML led us to hypothesize that WT1 mutations may impact TET2 function. WT1 mutant AML patients have reduced 5hmC levels similar to TET2/IDH1/IDH2 mutant AML. These mutations are characterized by convergent, site-specific alterations in DNA hydroxymethylation, which drive differential gene expression more than alterations in DNA promoter methylation. WT1 overexpression increases global levels of 5hmC, and WT1 silencing reduced 5hmC levels. WT1 physically interacts with TET2 and TET3, and WT1 loss of function results in a similar hematopoietic differentiation phenotype as observed with TET2 deficiency. These data provide a role for WT1 in regulating DNA hydroxymethylation and suggest that TET2 IDH1/IDH2 and WT1 mutations define an AML subtype defined by dysregulated DNA hydroxymethylation.

  4. Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes.

    Directory of Open Access Journals (Sweden)

    Greta E Weiss

    2015-02-01

    Full Text Available During blood stage Plasmodium falciparum infection, merozoites invade uninfected erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand binding events. Understanding each element in this process increases the potential to block the parasite's life cycle via drugs or vaccines. To investigate specific receptor-ligand interactions, they were systematically blocked using a combination of genetic deletion, enzymatic receptor cleavage and inhibition of binding via antibodies, peptides and small molecules, and the resulting temporal changes in invasion and morphological effects on erythrocytes were filmed using live cell imaging. Analysis of the videos have shown receptor-ligand interactions occur in the following sequence with the following cellular morphologies; 1 an early heparin-blockable interaction which weakly deforms the erythrocyte, 2 EBA and PfRh ligands which strongly deform the erythrocyte, a process dependant on the merozoite's actin-myosin motor, 3 a PfRh5-basigin binding step which results in a pore or opening between parasite and host through which it appears small molecules and possibly invasion components can flow and 4 an AMA1-RON2 interaction that mediates tight junction formation, which acts as an anchor point for internalization. In addition to enhancing general knowledge of apicomplexan biology, this work provides a rational basis to combine sequentially acting merozoite vaccine candidates in a single multi-receptor-blocking vaccine.

  5. Comparison of the Coe Thellier Thellier and microwave palaeointensity techniques using high-titanium titanomagnetites: results from a Tertiary basaltic intrusion from the Sydney Basin, New South Wales

    Science.gov (United States)

    Thomas, D. Neil; Hill, Mimi J.; Garcia, Alexander S.

    2004-12-01

    Conventional Thellier and microwave (MW) palaeointensity experiments, accompanied by rock magnetic tests, were conducted on samples from an early Tertiary (ca. 49 Ma) basaltic intrusion [the Peats Ridge (PR) basalt] from the Sydney Basin. Thermomagnetic and low-temperature susceptibility measurements suggest that the dominant magnetic mineral is Ti-enriched titanomagnetite (˜TM65-TM50) and hysteresis results indicate that the majority of samples exhibit PSD-like behaviour. Some samples show evidence of alteration, during laboratory heating, but only at temperatures in excess of 400 °C. No alteration is observed in the dominant temperature range (~70-300 °C) used for calculation of palaeointensities. Stepwise thermal demagnetisation studies reveal single component (after removal of a small viscous), reverse polarity magnetisations in all samples, with a mean characteristic remanence (ChRM) direction of D/I=197°/+60° ( α95=5°, k=62). Coe-Thellier-Thellier (CTT) experiments yielded a high success rate, with 68% of samples conforming to standard acceptance criteria. Microwave (MW) palaeointensity experiments, predominantly using the perpendicular applied field technique, produced a greater success rate of 82%. Mean palaeointensities of 27.1±4.4 μT ( N=21) and 27.4±4.0 μT ( N=28) were obtained from the CTT and MW techniques, respectively. These means could not be distinguished statistically, and the respective quality indicators were similar. These results suggest that the new microwave technique for calculating palaeointensities is, in this case, equivalent to the well-established CTT technique. This is an intuitive outcome, given that rock magnetic analyses suggest that alteration does not occur below the Curie temperature of the samples. Our results therefore provide a positive test for the equivalence of the MW and CTT techniques. The Virtual Dipole Moment (VDM) value for the intrusion is 4.7±0.7×10 22 Am 2, suggesting that the dipole field was

  6. The efficiency of tobacco Bel-W3 and native species for ozone biomonitoring in subtropical climate, as revealed by histo-cytochemical techniques

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Edenise S., E-mail: ealves@ibot.sp.gov.br [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Moura, Barbara B., E-mail: bmourabio@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Pedroso, Andrea N.V., E-mail: andreanvpedroso@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Tresmondi, Fernanda, E-mail: ftresmondi@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Domingos, Marisa, E-mail: mmingos@superig.com.br [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil)

    2011-12-15

    We aimed to verify whether hydrogen peroxide (H{sub 2}O{sub 2}) accumulation and cell death are detected early in three bioindicators of ozone (O{sub 3}), Nicotiana tabacum 'Bel-W3', Ipomoea nil 'Scarlet O'Hara' and Psidium guajava 'Paluma', and whether environmental factors also affect those microscopic markers. The three species were exposed to chronic levels of O{sub 3} in a subtropical area and a histo-cytochemical technique that combines 3,3'-diaminobenzidine (DAB) with Evans blue staining was used in the assessments. The three species accumulated H{sub 2}O{sub 2}, but a positive correlation with O{sub 3} concentration was only observed in N. tabacum. A positive correlation between O{sub 3} and cellular death was also observed in N. tabacum. In I. nil and P. guajava, environmental factors were responsible for symptoms at the microscopic level, especially in P. guajava. We conclude that the most appropriate and least appropriate bioindicator plant for O{sub 3} monitoring in the subtropics are N. tabacum 'Bel-W3' and P. guajava 'Paluma', respectively. - Highlights: > H{sub 2}O{sub 2} and cell death occur in response to O{sub 3} and other stressful factors. > H{sub 2}O{sub 2} can be detected by DAB and cell death by Evans blue staining. > These techniques contribute for analysis of susceptible bioindicator species. > H{sub 2}O{sub 2} and cell death were explained by high levels of O{sub 3} in N. tabacum 'Bel-W3'. > N. tabacum is the most appropriate plant for monitoring in subtropics. - Nicotiana tabacum 'Bel-W3' is better than native species for O{sub 3} biomonitoring in the subtropics, as revealed by histo-cytochemical techniques.

  7. Mapping Breakpoints of Complex Chromosome Rearrangements Involving a Partial Trisomy 15q23.1-q26.2 Revealed by Next Generation Sequencing and Conventional Techniques.

    Directory of Open Access Journals (Sweden)

    Qiong Pan

    Full Text Available Complex chromosome rearrangements (CCRs, which are rather rare in the whole population, may be associated with aberrant phenotypes. Next-generation sequencing (NGS and conventional techniques, could be used to reveal specific CCRs for better genetic counseling. We report the CCRs of a girl and her mother, which were identified using a combination of NGS and conventional techniques including G-banding, fluorescence in situ hybridization (FISH and PCR. The girl demonstrated CCRs involving chromosomes 3 and 8, while the CCRs of her mother involved chromosomes 3, 5, 8, 11 and 15. HumanCytoSNP-12 Chip analysis identified a 35.4 Mb duplication on chromosome 15q21.3-q26.2 in the proband and a 1.6 Mb microdeletion at chromosome 15q21.3 in her mother. The proband inherited the rearranged chromosomes 3 and 8 from her mother, and the duplicated region on chromosome 15 of the proband was inherited from the mother. Approximately one hundred genes were identified in the 15q21.3-q26.2 duplicated region of the proband. In particular, TPM1, SMAD6, SMAD3, and HCN4 may be associated with her heart defects, and HEXA, KIF7, and IDH2 are responsible for her developmental and mental retardation. In addition, we suggest that a microdeletion on the 15q21.3 region of the mother, which involved TCF2, TCF12, ADMA10 and AQP9, might be associated with mental retardation. We delineate the precise structures of the derivative chromosomes, chromosome duplication origin and possible molecular mechanisms for aberrant phenotypes by combining NGS data with conventional techniques.

  8. Clinical results of a surgical technique using endobuttons for complete tendon tear of pectoralis major muscle: report of five cases

    Directory of Open Access Journals (Sweden)

    Uchiyama Yoshiyasu

    2011-09-01

    Full Text Available Abstract Background We herein describe a surgical technique for the repair of complete tear of the pectoralis major (PM tendon using endobuttons to strengthen initial fixation. Methods Five male patients (3 judo players, 1 martial arts player, and 1 body builder were treated within 2 weeks of sustaining complete tear of the PM tendon. Average age at surgery and follow-up period were 28.4 years (range, 23-33 and 28.8 months (range, 24-36. A rectangular bone trough (about 1 × 4 cm was created on the humerus at the insertion of the distal PM tendon. The tendon stump was introduced into this trough, and fixed to the reverse side of the humeral cortex using endobuttons and non-absorbable suture. Clinical assessment of re-tear was examined by MRI. Shoulder range of motion (ROM, outcome of treatment, and isometric power were measured at final follow-up. Results There were no clinical re-tears, and MRI findings also showed continuity of the PM tendon in all cases at final follow-up. Average ROM did not differ significantly between the affected and unaffected shoulders. The clinical outcomes at final follow-up were excellent (4/5 cases or good (1/5. In addition, postoperative isometric power in horizontal flexion of the affected shoulder showed complete recovery when compared with the unaffected side. Conclusions Satisfactory outcomes could be obtained when surgery using the endobutton technique was performed within 2 weeks after complete tear of the PM tendon. Therefore, our new technique appears promising as a useful method to treat complete tear of the PM tendon.

  9. Atmosphere-Ionosphere Response to the M9 Tohoku Earthquake Revealed by Joined Satellite and Ground Observations. Preliminary results

    CERN Document Server

    Ouzounov, Dimitar; Romanov, Alexey; Romanov, Alexander; Tsybulya, Konstantin; Davidenko, Dimitri; Kafatos, Menas; Taylor, Patrick

    2011-01-01

    The recent M9 Tohoku Japan earthquake of March 11, 2011 was the largest recorded earthquake ever to hit this nation. We retrospectively analyzed the temporal and spatial variations of four different physical parameters - outgoing long wave radiation (OLR), GPS/TEC, Low-Earth orbit tomography and critical frequency foF2. These changes characterize the state of the atmosphere and ionosphere several days before the onset of this earthquake. Our first results show that on March 8th a rapid increase of emitted infrared radiation was observed from the satellite data and an anomaly developed near the epicenter. The GPS/TEC data indicate an increase and variation in electron density reaching a maximum value on March 8. Starting on this day in the lower ionospheric there was also confirmed an abnormal TEC variation over the epicenter. From March 3-11 a large increase in electron concentration was recorded at all four Japanese ground based ionosondes, which return to normal after the main earthquake. We found a positiv...

  10. Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription.

    Science.gov (United States)

    Hoffman, Elizabeth A; McCulley, Andrew; Haarer, Brian; Arnak, Remigiusz; Feng, Wenyi

    2015-03-01

    We have previously demonstrated that in Saccharomyces cerevisiae replication, checkpoint inactivation via a mec1 mutation leads to chromosome breakage at replication forks initiated from virtually all origins after transient exposure to hydroxyurea (HU), an inhibitor of ribonucleotide reductase. Here we sought to determine whether all replication forks containing single-stranded DNA gaps have equal probability of producing double-strand breaks (DSBs) when cells attempt to recover from HU exposure. We devised a new methodology, Break-seq, that combines our previously described DSB labeling with next generation sequencing to map chromosome breaks with improved sensitivity and resolution. We show that DSBs preferentially occur at genes transcriptionally induced by HU. Notably, different subsets of the HU-induced genes produced DSBs in MEC1 and mec1 cells as replication forks traversed a greater distance in MEC1 cells than in mec1 cells during recovery from HU. Specifically, while MEC1 cells exhibited chromosome breakage at stress-response transcription factors, mec1 cells predominantly suffered chromosome breakage at transporter genes, many of which are the substrates of those transcription factors. We propose that HU-induced chromosome fragility arises at higher frequency near HU-induced genes as a result of destabilized replication forks encountering transcription factor binding and/or the act of transcription. We further propose that replication inhibitors can induce unscheduled encounters between replication and transcription and give rise to distinct patterns of chromosome fragile sites.

  11. 454 Pyrosequencing and Sanger sequencing of tropical mycorrhizal fungi provide similar results but reveal substantial methodological biases.

    Science.gov (United States)

    Tedersoo, Leho; Nilsson, R Henrik; Abarenkov, Kessy; Jairus, Teele; Sadam, Ave; Saar, Irja; Bahram, Mohammad; Bechem, Eneke; Chuyong, George; Kõljalg, Urmas

    2010-10-01

    • Compared with Sanger sequencing-based methods, pyrosequencing provides orders of magnitude more data on the diversity of organisms in their natural habitat, but its technological biases and relative accuracy remain poorly understood. • This study compares the performance of pyrosequencing and traditional sequencing for species' recovery of ectomycorrhizal fungi on root tips in a Cameroonian rain forest and addresses biases related to multi-template PCR and pyrosequencing analyses. • Pyrosequencing and the traditional method yielded qualitatively similar results, but there were slight, but significant, differences that affected the taxonomic view of the fungal community. We found that most pyrosequencing singletons were artifactual and contained a strongly elevated proportion of insertions compared with natural intra- and interspecific variation. The alternative primers, DNA extraction methods and PCR replicates strongly influenced the richness and community composition as recovered by pyrosequencing. • Pyrosequencing offers a powerful alternative for the identification of ectomycorrhizal fungi in pooled root samples, but requires careful selection of molecular tools. A well-populated backbone database facilitates the detection of biological and technical artifacts. The pyrosequencing pipeline is available at http://unite.ut.ee/454pipeline.tgz.

  12. Deep scientific drilling results from Koyna and Killari earthquake regions reveal why Indian shield lithosphere is unusual, thin and warm

    Directory of Open Access Journals (Sweden)

    O.P. Pandey

    2016-09-01

    Full Text Available The nature of crustal and lithospheric mantle evolution of the Archean shields as well as their subsequent deformation due to recent plate motions and sustained intraplate geodynamic activity, has been a subject of considerable interest. In view of this, about three decades ago, a new idea was put forward suggesting that out of all shield terrains, the Indian shield has an extremely thin lithosphere (∼100 km, compared to 250–350 km, elsewhere, apart from being warm, non-rigid, sheared and deformed. As expected, it met with scepticism by heat flow and the emerging seismic tomographic study groups, who on the contrary suggested that the Indian shield has a cool crust, besides a coherent and thick lithosphere (as much as 300–400 km like any other shield. However, recently obtained integrated geological and geophysical findings from deep scientific drillings in 1993 Killari (Mw: 6.3 and 1967 Koyna (Mw: 6.3 earthquake zones, as well as newly acquired geophysical data over other parts of Indian shield terrain, have provided a totally new insight to this debate. Beneath Killari, the basement was found consisting of high density, high velocity mid crustal amphibolite to granulite facies rocks due to exhumation of the deeper crustal layers and sustained granitic upper crustal erosion. Similar type of basement appears to be present in Koyna region too, which is characterized by considerably high upper crustal temperatures. Since, such type of crust is depleted in radiogenic elements, it resulted into lowering of heat flow at the surface, increase in heat flow contribution from the mantle, and upwarping of the lithosphere-asthenosphere boundary. Consequently, the Indian shield lithosphere has become unusually thin and warm. This study highlights the need of an integrated geological, geochemical and geophysical approach in order to accurately determine deep crust-mantle thermal regime in continental areas.

  13. Metabolic profiling reveals altered pattern of central metabolism in navel orange plants as a result of boron deficiency.

    Science.gov (United States)

    Liu, Guidong; Dong, Xiaochang; Liu, Leichao; Wu, Lishu; Peng, Shu'ang; Jiang, Cuncang

    2015-04-01

    We focused on the changes of metabolite profiles in navel orange plants under long-term boron (B) deficiency using a gas chromatography-mass spectrometry (GC-MS) approach. Curling of the leaves and leaf chlorosis were observed only in the upper leaves (present before start of the treatment) of B-deficient plants, while the lower leaves (grown during treatment) did not show any visible symptoms. The metabolites with up-accumulation in B-deficient leaves were mainly proline, l-ornithine, lysine, glucoheptonic acid, fucose, fumarate, oxalate, quinate, myo-inositol and allo-inositol, while the metabolites with down-accumulation in B-deficient leaves were mainly serine, asparagine, saccharic acid, citrate, succinate, shikimate and phytol. The levels of glucose and fructose were increased only in the upper leaves by B deficiency, while starch content was increased in all the leaves and in roots. The increased levels of malate, ribitol, gluconic acid and glyceric acid occurred only in the lower leaves of B-deficient plants. The increased levels of phenols only in the upper leaves indicated that the effects of B on phenol metabolism in citrus plants may be a consequence of disruptions in leaf structure. Metabolites with opposite reactions in upper and lower leaves were mainly glutamine, glycine and pyrrole-2-carboxylic acid. To our knowledge, the phenomena of allo-inositol even higher than myo-inositol occurred characterized for the first time in this species. These results suggested that the altered pattern of central metabolism may be either specific or adaptive responses of navel orange plants to B deficiency. © 2014 Scandinavian Plant Physiology Society.

  14. Metabolic analysis revealed altered amino acid profiles in Lupinus albus organs as a result of boron deficiency.

    Science.gov (United States)

    Alves, Marta; Chicau, Paula; Matias, Helena; Passarinho, José; Pinheiro, Carla; Ricardo, Cândido Pinto

    2011-07-01

    We analysed the changes in the metabolites of Lupinus albus organs (leaf-blades, petioles, apexes, hypocotyls and roots) as a consequence of B deficiency. The deficiency did not affect malate concentration and induced only minor changes in the sugar content, suggesting that the carbohydrate metabolism is little affected by the deficiency. Contrarily, marked changes in the content of free amino acids were observed, with some specific variations associated with the different organs. These changes indicate that various aspects of metabolism implicated in the amino acid accumulation were affected by B deficiency. Most of the detected changes appear to have implications with some stress responses or signalling processes. Asparagine and proline that increase in many stresses also accumulated in petioles, apexes and hypocotyls. Accumulation of γ-aminobutyric acid shunt amino acids, indicative of production of reactive oxygen species, occurs in the same three organs and also the roots. The increase in the branched-chain amino acids, observed in all organs, suggests the involvement of B with the cytoskeleton, whereas glycine decrease in leaf-blades and active growing organs (apexes and roots) could be associated with the proposed role of this amino acids in plant signalling in processes that might be associated with the decreased growth rates observed in B deficiency. Despite the admitted importance of free amino acids in plant metabolism, the available information on this matter is scarce. So our results bring new information concerning the effects of B deficiency in the metabolism of the several L. albus organs. Copyright © Physiologia Plantarum 2011.

  15. Deep scientific drilling results from Koyna and Killari earthquake regions reveal why Indian shield lithosphere is unusual, thin and warm

    Institute of Scientific and Technical Information of China (English)

    O.P. Pandey

    2016-01-01

    The nature of crustal and lithospheric mantle evolution of the Archean shields as well as their subse-quent deformation due to recent plate motions and sustained intraplate geodynamic activity, has been a subject of considerable interest. In view of this, about three decades ago, a new idea was put forward suggesting that out of all shield terrains, the Indian shield has an extremely thin lithosphere (w100 km, compared to 250e350 km, elsewhere), apart from being warm, non-rigid, sheared and deformed. As expected, it met with scepticism by heat flow and the emerging seismic tomographic study groups, who on the contrary suggested that the Indian shield has a cool crust, besides a coherent and thick lithosphere (as much as 300e400 km) like any other shield. However, recently obtained integrated geological and geophysical findings from deep scientific drillings in 1993 Killari (Mw: 6.3) and 1967 Koyna (Mw: 6.3) earthquake zones, as well as newly acquired geophysical data over other parts of Indian shield terrain, have provided a totally new insight to this debate. Beneath Killari, the basement was found consisting of high density, high velocity mid crustal amphibolite to granulite facies rocks due to exhumation of the deeper crustal layers and sustained granitic upper crustal erosion. Similar type of basement appears to be present in Koyna region too, which is characterized by considerably high upper crustal temperatures. Since, such type of crust is depleted in radiogenic elements, it resulted into lowering of heat flow at the surface, increase in heat flow contribution from the mantle, and upwarping of the lithosphere-asthenosphere boundary. Consequently, the Indian shield lithosphere has become unusually thin and warm. This study highlights the need of an integrated geological, geochemical and geophysical approach in order to accurately determine deep crust-mantle thermal regime in continental areas.

  16. Characterization of Bond Strength of U-Mo Fuel Plates Using the Laser Shockwave Technique: Capabilities and Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    J. A. Smith; D. L. Cottle; B. H. Rabin

    2013-09-01

    This report summarizes work conducted to-date on the implementation of new laser-based capabilities for characterization of bond strength in nuclear fuel plates, and presents preliminary results obtained from fresh fuel studies on as-fabricated monolithic fuel consisting of uranium-10 wt.% molybdenum alloys clad in 6061 aluminum by hot isostatic pressing. Characterization involves application of two complementary experimental methods, laser-shock testing and laser-ultrasonic imaging, collectively referred to as the Laser Shockwave Technique (LST), that allows the integrity, physical properties and interfacial bond strength in fuel plates to be evaluated. Example characterization results are provided, including measurement of layer thicknesses, elastic properties of the constituents, and the location and nature of generated debonds (including kissing bonds). LST provides spatially localized, non-contacting measurements with minimum specimen preparation, and is ideally suited for applications involving radioactive materials, including irradiated materials. The theoretical principles and experimental approaches employed in characterizing nuclear fuel plates are described, and preliminary bond strength measurement results are discussed, with emphasis on demonstrating the capabilities and limitations of these methods. These preliminary results demonstrate the ability to distinguish bond strength variations between different fuel plates. Although additional development work is necessary to validate and qualify the test methods, these results suggest LST is viable as a method to meet fuel qualification requirements to demonstrate acceptable bonding integrity.

  17. [A new mini-invasive technique for the treatment of sleep breathing disorders: preliminary results of a clinical experience].

    Science.gov (United States)

    Fibbi, A; Presta, A; Fasciolo, G

    1999-02-01

    The REPOSE system is a new, mini-invasive technique with which the base of the tongue is suspended to treat sleep breathing disorders (SBD) induced by hypertrophy of the base of the tongue. The surgical technique calls for the intra-oral insertion of a small titanium screw in the anterior portion of the mandible. Two polypropylene threads are attached to the screw and these are passed through the base of the tongue and then tied at the point where it is inserted in the floor of the mouth, thus effectively suspending the base of the tongue. 10 patients with SBD due to hypertrophy of the base of the tongue underwent this procedure. Only one major complication was found: an infection requiring sectioning of the suspension thread. For an average 7 to 30 days all patients showed signs of odinophagia, bilateral otalgia, dysphagia and dislalia. In all patients snoring either disappeared altogether or was significantly reduced. Statistical analysis of the pre- and post-operative polysonnograph data showed a significant reduction in the apnea index (AI), the respiratory distress index (RDI) (p = 0.009) as well as a significant improvement in the degree of oxygen saturation (SaO2) (p = 0.008). The results were independent from the body mass since the patients did not lose weight during the follow-up period.

  18. ARTHRODESIS OF THE FIRST METATARSOPHALANGEAL JOINT IN PATIENTS WITH RHEUMATOID ARTHRITIS AND HALLUX VALGUS: CHOICE OF TECHNIQUE OF ARTHRODESIS FIXATION, COMPLICATIONS AND LONG-TERM RESULTS

    Directory of Open Access Journals (Sweden)

    V. P. Pavlov

    2014-01-01

    Full Text Available Objective: to study results of arthrodesis of the first metatarsophalangeal joint (I MPT joint in patients with rheumatoidarthritis (RA and hallux valgus, assess methods of arthrodesis fixation, reveal complications and analyze longterm results.Subjects and methods. Authors observed 86 patients with RA, female : male ratio 3.2:1, mean age was 53.8±9.5 years (from 18 to 75 years; 80 from them had seropositive and 6 – seronegative RA. 72 patients had low, and 14 –moderate activity of the disease. II stage of RA was revealed in 31.4%, III – in 62.8%, IV – in 5.8%; 52.3% of  patients had I and 47.7% – II functional class. All patients  ad hallux valgus as a component of typical deformation of the forefoot – digitis V rheumaticus (DVR. Standard global reconstructive operation (SGRO and its modification (MGRO were used. Both techniques included arthrodesis of the I MTP joint where fusion of bones was fixed with Kirschner wire and compression clamps in groups A and B respectively. Results of surgical treatmentwere assessed separately for I and II–V toes. The present work provides solely the results of the I MTP joint arthrodesis.Results. Assessment of the I MTP joint with hallux valgus before and 2.3±1.5 years after operation based on AOFAS comprised 35.51±8.16/82.32±6.09 in the group A and 39.93±6.65/82.26±5,59 in the group B. Inefficiency of arthrodesis of the I MTP joint was observed in 3 patients from the group B (2.15%. Before operation, 3 from 141 feet had hallux valgus of the II stage (21–40°; III (41–60° and IV (>60° stages of hallux valgus were recorded in 90 and48 feet respectively. Following 2.3 years after arthrodesis normal I MTP joints (10–11° were observed in 131 feet whereas, that of the II stage of hallux valgus (12–20° – in 10 feet.Conclusion. High efficacy of arthrodesis of the I MTP joint in patients with RA and hallux valgus and, subsequently, low failure rate (2.15% were achieved as

  19. Quartz preferred orientation in naturally deformed mylonitic rocks (Montalto shear zone-Italy): a comparison of results by different techniques, their advantages and limitations

    Science.gov (United States)

    Fazio, Eugenio; Punturo, Rosalda; Cirrincione, Rosolino; Kern, Hartmut; Pezzino, Antonino; Wenk, Hans-Rudolf; Goswami, Shalini; Mamtani, Manish A.

    2016-12-01

    In the geologic record, the quartz c-axis patterns are widely adopted in the investigation of crystallographic preferred orientations (CPO) of naturally deformed rocks. To this aim, in the present work, four different methods for measuring quartz c-axis orientations in naturally sheared rocks were applied and compared: the classical universal stage technique, the computer-integrated polarization microscopy method (CIP), the time-of-flight (TOF) neutron diffraction analysis , and the electron backscatter diffraction (EBSD). Microstructural analysis and CPO patterns of quartz, together with the ones obtained for feldspars and micas in mylonitic granitoid rocks, have been then considered to solve structural and geological questions related to the Montalto crustal scale shear zone (Calabria, southern Italy). Results obtained by applying the different techniques are discussed, and the advantages as well as limitations of each method are highlighted. Importantly, our findings suggest that patterns obtained by means of different techniques are quite similar. In particular, for such mylonites, a subsimple shear (40% simple shear vs 60% pure shear) by shape analysis of porphyroclasts was inferred. A general tendency of an asymmetric c-maximum near to the Z direction (normal to foliation) suggesting dominant basal slip, consistent with fabric patterns related to dynamically recrystallization under greenschist facies, is recognized. Rhombohedral slip was likely active as documented by pole figures of positive and negative rhombs (TOF), which reveal also potential mechanical Dauphiné twinning. Results showed that the most complete CPO characterization on deformed rocks is given by the TOF (from which also other quartz crystallographic axes can be obtained as well as various mineral phases may be investigated). However, this use is restricted by the fact that (a) there are very few TOF facilities around the world and (b) there is loss of any domainal reference, since TOF is a

  20. Percutaneous internal jugular venous cannulation for extracorporeal circulation during minimally invasive technique in children with congenital heart disease: operative technique and results.

    Science.gov (United States)

    Vida, Vladimiro L; Tiberio, Ivo; Gallo, Michele; Guariento, Alvise; Suti, Emirjeta; Pittarello, Demetrio; Stellin, Giovanni

    2016-10-01

    The aim of this study was to evaluate the safety and efficacy of the percutaneous cannulation of the internal jugular venous (PCIJV) for extracorporeal circulation during minimally invasive cardiac surgery (MICS) in children with simple congenital heart disease. From September 2007, 83 children (<16 years) underwent PCIJV for extracorporeal circulation. Primary outcome of the study was to evaluate the safety and advantages of PCIJV technique. Technical steps and pitfalls of PCIJV technique are described. Median age at surgery was 9 years (range 3.5-16 years) and median body weight was 31 kilograms (range 13-72 kilograms); 32 patients (40%) had a body weight less than 30 kilograms. The PCIJV was achieved with a 14 French cannula in 61 pts (73%), with a 17 Fr cannula in 22 (23%). The PIJVC was judged difficult in 2 patients (2.4%); in both of them cannulation was achieved at a different venous site There were no procedure-related complications and no flow disturbances during the extracorporeal circulation. The PCIJV during MICS is an effective and reproducible technique for achieving peripheral CPB in children with simple CHDs. We progressively expanded the use of this technique in smaller children and this allows us to further minimize surgical trauma without experiencing venous drainage's problems.

  1. Perisciatic Ultrasound-Guided Infiltration for Treatment of Deep Gluteal Syndrome: Description of Technique and Preliminary Results.

    Science.gov (United States)

    Rosales, Julio; García, Nicolás; Rafols, Claudio; Pérez, Marcelo; Verdugo, Marco A

    2015-11-01

    The objective of this study was to describe a perisciatic ultrasound-guided infiltration technique for treatment of deep gluteal syndrome and to report its preliminary clinical results. A mixture of saline (20 mL), a local anesthetic (4 mL), and a corticosteroid solution (1 mL) was infiltrated in the perisciatic region between the gluteus maximus and pelvitrochanteric muscles. Relative pain relief was achieved in 73.7% of the patients, with average preprocedural and postprocedural visual analog scale scores of 8.3 and 2.8, respectively. Fifty percent of patients reported recurrence of discomfort, and the average duration of the therapeutic effect in these patients was 5.3 weeks.

  2. Randomised Response Technique-An Innovative Method To Measure Culturally Sensitive Variables : Results From A Pilot Study

    Directory of Open Access Journals (Sweden)

    Soudarssanane M. B

    2003-01-01

    Full Text Available Research questions: What is the advantage of Randomized Response Technique (RRT over the conventional Direct Interview (DI and Anonymous Questionnaire (AQ in the assessment of culturally sensitive variables? Objectives: To compare the efficacy of the three methods, namely RRT, DI and AQ in the measurement of prevalence of Pre/Extra marital sex. Study design: Cross sectional study, using the three methods. Setting: A pilot study in a given community in Pondicherry. Statistical analysis: Probability equations. Results: The prevalence of pre/extra marital sex in the study population by the DI, AQ and RRT methods were 0%, 6% and 10% respectively in this pilot study. Conclusion: RRT improves validity of measurement of culturally sensitive variables both by ensuring a high participation in the study and by enabling a true response by assuring full confidentiality of information.

  3. Flight test results for the F-8 digital fly-by-wire aircraft control sensor analytic redundancy management technique

    Science.gov (United States)

    Deckert, J. C.

    1981-01-01

    This paper reviews the formulation and flight test results of an algorithm to detect and isolate the first failure of any one of twelve duplex control sensor signals being monitored. The technique uses like-signal differences for fault detection while relying upon analytic redundancy relationships among unlike quantities to isolate the faulty sensor. The fault isolation logic utilizes the modified sequential probability ratio test, which explicitly accommodates the inevitable irreducible low frequency errors present in the analytic redundancy residuals. In addition, the algorithm uses sensor output selftest, which takes advantage of the duplex sensor structure by immediately removing a highly erratic sensor from control calculations and analytic redundancy relationships while awaiting a definitive fault isolation decision via analytic redundancy. This study represents a proof of concept demonstration of a methodology that can be applied to duplex or higher flight control sensor configurations and, in addition, can monitor the health of one simplex signal per analytic redundancy relationship.

  4. Percutaneous Nucleoplasty Using Coblation Technique for the Treatment of Chronic Nonspecific Low Back Pain: 5-year Follow-up Results

    Institute of Scientific and Technical Information of China (English)

    Da-Jiang Ren; Xiu-Mei Liu; Sui-Yong Du; Tian-Sheng Sun; Zhi-Cheng Zhang; Fang Li

    2015-01-01

    Background:This study evaluated the efficacy of percutaneous nucleoplasty using coblation technique for the treatment of chronic nonspecific low back pain (LBP),after 5 years of follow-up.Methods:From September 2004 to November 2006,172 patients underwent percutaneous nucleoplasty for chronic LBP in our department.Forty-one of these patients were followed up for a mean period of 67 months.Nucleoplasty was performed at L3/4 in 1 patient;L4/5 in 25 patients;L5/S1 in 2 patients;L3/4 and L4/5 in 2 patients;L4/5 and L5/S1 in 7 patients;and L3/4,L4/5,and L5/S1 in 4 patients.Patients were assessed preoperatively and at 1 week,1 year,3 years,and 5 years postoperatively.Pain was graded using a 10-cm Visual Analogue Scale (VAS) and the percentage reduction in pain score was calculated at each postoperative time point.The Oswestry Disability Index (ODI) was used to assess disability-related to lumbar spine degeneration,and patient satisfaction was assessed using the modified MacNab criteria.Results:There were significant differences among the preoperative,1-week postoperative,and 3-year postoperative VAS and ODI scores,but not between the 3-and 5-year postoperative scores.There were no significant differences in age,sex,or preoperative symptoms between patients with effective and ineffective treatment,but there were significant differences in the number of levels treated,Pfirrmann grade of intervertebral disc degeneration,and provocative discography findings between these two groups.Excellent or good patient satisfaction was achieved in 87.9% of patients after 1 week,72.4% after 1 year,67.7% after 3 years,and 63.4% at the last follow-up.Conclusions:Although previously published short-and medium-term outcomes after percutaneous nucleoplasty appeared to be satisfactory,our long-term follow-up results show a significant decline in patient satisfaction over time.Percutaneous nucleoplasty is a safe and simple technique,with therapeutic effectiveness for the treatment of

  5. Evaluation of the incidence on insufficient cytology results comparing different ultrasound-guided aspiration techniques for thyroid nodules

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seong Hyng; Park, Jun Hyun; Park, Ji Kang [Dept. of Radiology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju (Korea, Republic of)

    2013-07-15

    We compared the incidence of insufficient thyroid cytology due to blood-stained materials or low cellularity in terms of aspiration technique, especially focusing on the degree of suction pressure and needle size. Three experienced radiologists performed ultrasound-guided aspiration for thyroid nodules in 1174 thyroid nodules consecutively. Three different techniques were used; (A) using a 25 gauge needle with mainly capillary technique in 269 nodules; (B) using a 25 gauge needle with 3 cc syringe and minimal suction pressure in 303 nodules; (C) using a 22-23 gauge needle with 10 cc syringe and aspirator in 602 nodules. The differences of the incidence of the insufficient cytology among the three aspiration techniques and relationships of the incidence and needle size/degree of suction pressure was statistically analyzed using the Mann-Whitney U test and the chi-square test with linear-by-linear association. Overall, the difference in insufficient cytology was significant across the three aspiration technique (p = 0.004), and the incidence tended to increase significantly with increase of needle size and degree of suction pressure (p < 0.001). A pairwise comparison of aspiration techniques found significant differences (p = 0.003) between techniques (A) and (C), and no differences between technique (B) and (C) (p 0.07) and between techniques (A) and (B) (p = 0.10). The incidence of insufficient cytology was significantly low in the capillary technique, and it increased significantly with the increase of needle size and degree of suction pressure.

  6. Caveats in transneuronal tracing with unmodified rabies virus: an evaluation of aberrant results using a nearly perfect tracing technique

    Directory of Open Access Journals (Sweden)

    Tom J.H. Ruigrok

    2016-07-01

    Full Text Available Apart from the genetically engineered, modified, strains of rabies virus (RABV, unmodified ‘fixed’ virus strains of RABV, such as the ‘French’ subtype of CVS11, are used to examine synaptically connected networks in the brain. This technique has been shown to have all the prerequisite characteristics for ideal tracing as it does not metabolically affect infected neurons within the time span of the experiment, it is transferred transneuronally in one direction only and to all types of neurons presynaptic to the infected neuron, number of transneuronal steps can be precisely controlled by survival time and it is easily detectable with a sensitive technique.Here, using the ‘French’ CVS 11 subtype of RABV in Wistar rats, we show that some of these characteristics may not be as perfect as previously indicated. Using injection of RABV in hind limb muscles, we show that RABV-infected spinal motoneurons may already show lysis 1 or 2 days after infection. Using longer survival times we were able to establish that Purkinje cells may succumb approximately 3 days after infection. In addition, some neurons seem to resist infection, as we noted that the number of RABV-infected inferior olivary neurons did not progress in the same rate as other infected neurons. Furthermore, in our hands, we noted that infection of Purkinje cells did not result in expected transneuronal labeling of cell types that are presynaptic to Purkinje cells such as molecular layer interneurons and granule cells. However, these cell types were readily infected when RABV was injected directly in the cerebellar cortex. Conversely, neurons in the cerebellar nuclei that project to the inferior olive did not take up RABV when this was injected in the inferior olive, whereas these cells could be infected with RABV via a transneuronal route. These results suggest that viral entry from the extracellular space depends on other factors or mechanisms than those used for retrograde

  7. Generating Representative Sets and Summaries for Large Collection of Images Using Image Cropping Techniques and Result Comparison

    Directory of Open Access Journals (Sweden)

    Abdullah Al-Mamun

    2015-11-01

    Full Text Available The collection of photos hosted on photo archives and social networking sites has been increasing exponentially. It is really hard to get the summary of a large image set without browsing through the entire collection. In this paper two different techniques of image cropping (random windows technique and sequential windows technique have been proposed to generate effective representative sets. A ranking mechanism has been also proposed for finding the best representative set.

  8. [Liver transplantation--indications, surgical technique, results--the analysis of a clinical series of 200 cases].

    Science.gov (United States)

    Popescu, I; Ionescu, M; Braşoveanu, V; Hrehoreţ, D; Matei, E; Dorobantu, B; Zamfir, R; Alexandrescu, S; Grigorie, M; Tulbure, D; Popa, L; Ungureanu, M; Tomescu, D; Droc, G; Popescu, H; Cristea, A; Gheorghe, L; Iacob, S; Gheorghe, C; Boroş, M; Lupescu, I; Vlad, L; Herlea, V; Croitoru, M; Platon, P; Alloub, A

    2010-01-01

    Initially considered experimental, liver transplantation (LT) has become the treatment of choice for the patients with end-stage liver diseases. Between April 2000 and October 2009, 200 LTs (10 reLTs) were performed in 190 patients, this study being retrospective. There were transplanted 110 men and 80 women, 159 adults and 31 children with the age between 1 and 64 years old (mean age--39.9). The main indication in the adult group was represented by viral cirrhosis, while the pediatric series the etiology was mainly glycogenosis and biliary atresia. There were performed 143 whole graft LTs, 46 living donor LTs, 6 split LTs, 4 reduced LTs and one domino LT RESULTS: The postoperative survival was 90% (170 patients). The patient and graft one-year and five-year survivals were 76.9%, 73.6% and 71%, 68.2%, respectively. The early complications occurred in 127 patients (67%). The late complications were recorded in 71 patients (37.3%). The intraoperative and early postoperative mortality rate was 9.5% (18 patients). The Romanian liver transplantation program from Fundeni includes all types of current surgical techniques and the results are comparable with those from other international centers.

  9. Comparison of oncological results and functional outcomes of radical prostatectomy techniques – retropubic, laparoscopic and robot-assisted

    Directory of Open Access Journals (Sweden)

    E. A. Prilepskaya

    2015-01-01

    Full Text Available Radical prostatectomy (RP continues to be the «gold standard» in the treatment of localized prostate cancer (PC for patients with a life expectancy of 10 years.The purpose of this article is to review pertinent literature to the several surgical approaches for PC and compare both functional outcomes and oncological results of radical retropubic prostatectomy (RRP, laparoscopic radical prostatectomy (LRP and robot-assisted radical prostatectomy (RARP. We chose and systematically reviewed 44 articles published between 1999 and 2013. Comparison analysis showed that the mean blood loss during RRP, LRP and RARP was 935, 442 and 191 ml respectively. Intraoperative transfusion required 19,9; 6,3 and 4,6 % patients respectively. We’d like to outline in our functional outcomes that within the 6-months and 12-months period of follow-up acute urinary retention experienced 89,1 and 92,7 % patients undergoing RARP.However, lack of certain data and absence of standard assessment methods made objective evaluation of erectile function quite complex. Oncologic results revealed that positive surgical margin rates were higher for RARP in comparison to patients after RRP and LRP (the difference was statistically significant.Nevertheless, the absence of randomized approach in an overwhelming majority of cases, as well as the short follow-up period are serious deterrents limiting the number of such trials. Therefore it’s still impossible today to draw certain conclusions about the superiority of any surgical approach for RP

  10. Transarterial Chemoembolization (TACE) in hepatocellular carcinoma: Technique, indication and results; Transarterielle Chemoembolisation (TACE) des hepatozellulaeren Karzinoms: Technik, Indikationsstellung und Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, T.J.; Zangos, S.; Balzer, J.O.; Nabil, M.; Rao, P.; Eichler, K.; Abdelkader, A. [Inst. fuer Diagnostische und Interventionelle Radiologie, J.W. Goethe-Univ., Frankfurt (Germany); Bechstein, W.O. [Klinik fuer Allgemeinchirurgie, J.W. Goethe-Univ., Frankfurt (Germany); Zeuzem, S. [Klinik fuer Innere Medizin, Hepatologie, J.W. Goethe-Univ., Frankfurt (Germany)

    2007-11-15

    To present current data on technique, indications and results of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). The principle of TACE is the intra-arterial injection of chemotherapeutic drug combinations like doxorubicin, cisplatin and mitomycin into the hepatic artery, followed by lipiodol injection, Gelfoam for vessel occlusion and degradable microspheres. The side effects and complications after TACE range from fever, upper abdominal pain and vomiting to acute or chronic liver cell failure. The palliative effect in unresectable HCC using TACE allows local tumor control in 15 to 60% of cases and 5-year survival rates ranging from 8 - 43%. The potentially curative treatment option allows local tumor control from 18 - 63%. The neoadjuvant treatment option of TACE in combination with other treatment options like percutaneous ethanol injection (PEI) or radiofrequency ablation (RFA) reach local tumor control rates between 80 - 96%. The bridging effect of TACE before liver transplantation reaches 5-year survival rates from 59 - 93%. The symptomatic therapy option of TACE is used to counteract pain directly caused by HCC and acute/subacute bleeding in the HCC. The local tumor response reaches up to 88% and the bleeding control is from 83 to 100%. (orig.)

  11. Use of relaxation techniques and complementary and alternative medicine by American adults with insomnia symptoms: results from a national survey.

    Science.gov (United States)

    Bertisch, Suzanne M; Wells, Rebecca Erwin; Smith, Michael T; McCarthy, Ellen P

    2012-12-15

    Though relaxation training is recommended for insomnia, national patterns of use remain unknown. Similarly, rates of complementary and alternative medicine (CAM) use by adults with insomnia are not well established. We sought to elucidate the patterns and reasons for use of relaxation techniques and CAM use by adults with insomnia symptoms. We used the 2007 National Health Interview Survey (n = 23,358) to estimate prevalence of use among adults by self-reported insomnia symptom status. Among adults reporting insomnia symptoms (n = 4,415), we examined reasons for use and disclosure to medical professionals. We employed logistic regression to determine the adjusted associations between relaxation techniques use, CAM use, and insomnia symptoms. Among adults with insomnia symptoms, 23% used relaxation techniques and 45% used CAM annually. After adjustment, adults with insomnia symptoms had higher likelihood of using relaxation techniques (aOR 1.48, 95% CI 1.32, 1.66) and CAM (aOR 1.29, 95% CI 1.15, 1.44) compared with adults without insomnia. Deep breathing exercise was the most commonly used relaxation technique. Fewer than 2% of adults with insomnia used CAM specifically for insomnia. Only 26% of adults with insomnia symptoms disclosed their relaxation techniques use to medical professionals. Being male, lower educational and physical activity levels, income relaxation techniques use among adults with insomnia symptoms. While adults with insomnia symptoms commonly use relaxation techniques and CAM, few are using for their insomnia. Facilitating discussions about relaxation techniques may foster targeted use for insomnia.

  12. Fontan Operation and the Cavopulmonary Technique: Immediate and Late Results According to the Presence of Atrial Fenestration

    Directory of Open Access Journals (Sweden)

    Edmar Atik

    2002-02-01

    Full Text Available OBJECTIVE: To compare immediate and late results in patients with or without fenestration who underwent cavopulmonary anastomosis so that we could assess the efficiency of the technique. METHODS: Sixty-two patients underwent surgery between 1988 and 1999, 41 with fenestration (group I -G I and 21 without fenestration (group II -G II. Tricuspid atresia was prevalent in group I (23-56% and single ventricle was prevalent in group II (14-66%. Mean ages at the time of operation were 7.3 years in group I and 7.6 in group II. At late follow-up, mean ages were 10.6 years in group I and 12.8 years in group II. RESULTS: Immediate and late mortality were 7.3% in G-I and 4.7% in G-II. Significant pleural effusion occurred in 41.4% of G-I patients and in 23.8% of G-II patients. Significant pericardial effusion occurred in 29.2% and 14.2%, respectively, in groups I and II. Central venous pressure was greater in G-II, 17.7 cm in H2O, as opposed to 15 cm in G-I. Hospital stay was similar between the groups, 26.3 and 21.8 days, respectively. Cyanosis and arterial insaturation occurred in 5 patients, and 4 patients were in functional class II, all from G-I. At late follow-up, 58 (93.5% were in functional class I. Sinus rhythm was present in 94%, and pulmonary perfusion was similar in both groups. Eleven patients who underwent spirometry had good tolerance to physical effort. CONCLUSION: Atrial fenestration did not improve the immediate or late follow-up of patients who underwent cavopulmonary anastomosis, and is, therefore, dispensable.

  13. Mexico City land subsidence in 2014-2015 with Sentinel-1 IW TOPS: Results using the Intermittent SBAS (ISBAS) technique

    Science.gov (United States)

    Sowter, Andrew; Bin Che Amat, Moh.; Cigna, Francesca; Marsh, Stuart; Athab, Ahmed; Alshammari, Lubna

    2016-10-01

    Differential Interferometric Synthetic Aperture Radar (DInSAR) can be considered as an efficient and cost effective technique for monitoring land subsidence due to its large spatial coverage and high accuracy provided. The recent commissioning of the first Sentinel-1 satellite offers improved support to operational surveys using DInSAR due to regular observations from a wide-area product. In this paper we show the results of an intermittent small-baseline subset (ISBAS) time-series analysis of 18 Interferometric Wide swath (IW) products of a 39,000 km2 area of Mexico acquired between 3 October 2014 and 7 May 2015 using the Terrain Observation with Progressive Scans in azimuth (TOPS) imaging mode. The ISBAS processing was based upon the analysis of 143 small-baseline differential interferograms. After the debursting, merging and deramping steps necessary to process Sentinel-1 IW products, the method followed a standard approach to the DInSAR analysis. The Sentinel-1 ISBAS results confirm the magnitude and extent of the deformation that was observed in Mexico City, Chalco, Ciudad Nezahualcóyotl and Iztapalapa by other C-band and L-band DInSAR studies during the 1990s and 2000s. Subsidence velocities from the Sentinel-1 analysis are, in places, in excess of -24 cm/year along the satellite line-of-sight, equivalent to over ∼40 cm/year vertical rates. This paper demonstrates the potential of Sentinel-1 IW TOPS imagery to support wide-area DInSAR surveys over what is a very large and diverse area in terms of land cover and topography.

  14. Bio-functions and molecular carbohydrate structure association study in forage with different source origins revealed using non-destructive vibrational molecular spectroscopy techniques

    Science.gov (United States)

    Ji, Cuiying; Zhang, Xuewei; Yan, Xiaogang; Mostafizar Rahman, M.; Prates, Luciana L.; Yu, Peiqiang

    2017-08-01

    The objectives of this study were to: 1) investigate forage carbohydrate molecular structure profiles; 2) bio-functions in terms of CHO rumen degradation characteristics and hourly effective degradation ratio of N to OM (HEDN/OM), and 3) quantify interactive association between molecular structures, bio-functions and nutrient availability. The vibrational molecular spectroscopy was applied to investigate the structure feature on a molecular basis. Two sourced-origin alfalfa forages were used as modeled forages. The results showed that the carbohydrate molecular structure profiles were highly linked to the bio-functions in terms of rumen degradation characteristics and hourly effective degradation ratio. The molecular spectroscopic technique can be used to detect forage carbohydrate structure features on a molecular basis and can be used to study interactive association between forage molecular structure and bio-functions.

  15. Long-term results and comparison of the three different high tibial osteotomy and fixation techniques in medial compartment arthrosis.

    Science.gov (United States)

    Polat, Gökhan; Balcı, Halil İbrahim; Çakmak, Mehmet Fevzi; Demirel, Mehmet; Şen, Cengiz; Aşık, Mehmet

    2017-03-16

    The purpose of this study is to report and analyze the long-term outcomes of the patients who underwent high tibial osteotomy (HTO) with three different techniques for the treatment of medial compartment arthrosis. A total of 187 patients (195 knees) who underwent HTO between 1990 and 2010 were retrospectively evaluated. Eighty-eight knees, opening-wedge osteotomy with Puddu plate (group A); 51 knees, transverse osteotomy below the tubercle with external fixator (group B); and 29 knees, closing-wedge osteotomy with staple fixation (group C) were included in the study. The patients (mean age 44.9 ± 10.6 years, mean follow-up of 12.4 ± 3.2 years) were called for final controls and survival rates of the knees, and functional evaluations of the patients were performed using Knee Society Score (KSS) and Hospital for Special Surgery (HSS) knee score assessments. In the comparison of the three groups, there were no differences regarding the mean age, preoperative arthrosis levels, or preoperative deformity analyses (n.s.). The main finding of these comparisons showed that the closing-wedge osteotomy has the greatest lateralization effect on mechanical axis deviation (MAD) (p = 0.024), the greatest valgization effect on medial proximal tibial angles (MPTA) (p = 0.026), and the lowest posterior tibial slope (PTS) angles (p = 0.032) in comparison to the other groups. There were no functional differences between the three groups in the long-term assessment of patients with KSS and HSS knee scores. According to the Kaplan-Meier survival analysis, the probability of the survival of the native knee joint after HTO was 93.4% in 5 years and 71.2% in 10 years in our study group. During the follow-up of the 168 knees, revision surgery with total knee replacement was needed in 27 knees (16%). The mean time from HTO to total knee replacement was 8.9 years in these patients. HTO has acceptable long-term clinical and functional results that should not be

  16. Techniques and results of extremities dosimetric assessments among interventional imagery operators; Techniques et resultats d'evaluations dosimetriques des extremites chez les operateurs en imagerie interventionnelle

    Energy Technology Data Exchange (ETDEWEB)

    Donadille, L.; Tagnard-Merat, F.; Rehel, J.L. [Institut de Radioprotection et de Surete Nucleaire, 92 - Fontenay aux Roses (France); Gauron, C. [Institut national de recherche et de securite pour la prevention des accidents du travail et des maladies professionnelles (INRS), Centre de Paris, 30 rue Olivier Noyer, 75680 Paris Cedex 1 4 (France)

    2009-07-01

    The authors evoke different surveys made among interventional imagery operators to assess the doses received by their hands. The operators had a local dosimeter on their middle finger nail during a single procedure, and had then to fill in a questionnaire. At least ten measurements per operator are required for the survey. The survey started in 2008 and is planned to end in December 2009. Some results are already briefly discussed

  17. Tenodese bicipital "a rocambole": técnica e resultados "Rocambole-like" biceps tenodesis: technique and results

    Directory of Open Access Journals (Sweden)

    Glaydson Gomes Godinho

    2011-01-01

    ,883, com a prática esportiva (p = 0,195 ou com a lesão associada do subescapular (p = 0,958.OBJECTIVE: To present a new technique for bicipital tenodesis and its results: accomplished partially via arthroscopy and grounded in concepts of the normal and pathological anatomy of the tendon of the biceps long head. It is based on the predisposition of this tendon towards becoming attached to the intertubercular sulcus after rupture or tenotomy (auto-tenodesis. METHODS: Evaluations were conducted on 63 patients (63 shoulders, aged from 32 to 77 years (average 55, consisting of 32 females (51% and 31 males (49%. Thirty-five of the patients (55.6% were over 60 years of age and 28 patients (44.4% were under 60 years of age. Eighteen were sports participants (28.6%. Fourteen had injuries associated with the subscapularis (22.2%. The average follow up was 43 months (ranging from 12 to 74 months. The right shoulder accounted for 48 cases (76.2%, of which one was a left-handed individual and 47 were right-handed. The left shoulder accounted for 15 (23% of the patients, of whom two were left-handed and 13 were right-handed. There were no bilateral occurrences. The statistical analysis were done using SPSS version 18. Pearson's chi-square test and continuity corrections were used to investigate the statistical significance of associations between variables. Associations were taken to be statistically significant when p was less than 0.05. RESULTS: Residual Popeye deformity was perceived by seven patients (11.1%; it was only observed by the examiner in 15 cases (23.8%; and neither the patient nor the examiner observed it in 41 cases (65%. There were no statistically valid influences from age, participation in contact or throwing sports, subscapularis tendon-associated injury or Popeye deformity. Fifty-eight patients (92.06% were satisfied, two patients were dissatisfied (3.17% and three patients were indifferent (4.76%. CONCLUSION: The technique presented high patient satisfaction

  18. Tracing transfer processes of metal pollutants from soils to surface water using environmental magnetic techniques - results from Paris suburbia (France)

    Science.gov (United States)

    Franke, Christine; Lamy, Isabelle; van Oort, Folkert; Thiesson, Julien; Barsalini, Luca

    2015-04-01

    Major river systems in Europe are potential sinks for environmental pollutions and therefore reflect the consequences of European industrialization and urbanization. Surface water pollution is a major concern for the health of the population and its related ecosystems as well as for the water quality. Within the variety of different typical pollutants in a river watershed, the metallic fraction embraces many toxic/dangerous contaminants. Each of these elements comprises different sources and follows specific processes throughout its pathways from its origin to and within the river system. But the detection, estimation and follow up of the different contaminants is highly complex. Physico-chemical techniques such as environmental and rock magnetics are powerful complementary tools to traditional methods because they comprise the possibility to trace the entire metal fraction and do offer the possibility to perform spatio-temporal analyze campaigns directly in the field and on a relative high number of samples from both the river and the adjacent areas (suspended particular matter, soils, dust, sediments, etc). In this study, we took advantages of the recent results on the Seine river (France) that have shown the high potential of environmental magnetic methods to estimate the metal fraction in suspended particular matter samples, and to allow the discrimination of its natural detrital, biogenic or anthropogenic origin (see parallel EGU abstract of Kayvantash et al. in this session). We focused on a suburban agricultural area west of Paris (Pierrelaye-Bessancourt) adjacent to the Seine river, which suffers from a high accumulation of heavy metal pollutants caused by long-term historical irrigation with urban waste waters. For the time being, these heavy metals seem to be geochemically fixed in the surface layer mainly by the soil organic matter. Future land use planning, however, arises questions on the fate of these pollutants and their potential remobilization by

  19. Intermediate to long-term results following the bernese periacetabular osteotomy and predictors of clinical outcome: surgical technique.

    Science.gov (United States)

    Matheney, Travis; Kim, Young-Jo; Zurakowski, David; Matero, Catherine; Millis, Michael

    2010-09-01

    The Bernese periacetabular osteotomy is a commonly used non-arthroplasty option to treat developmental hip dysplasia in symptomatic younger patients. Predicting which hips will remain preserved and which hips will go on to require arthroplasty following periacetabular osteotomy is a major challenge. In the present study, we assessed the intermediate to long-term results following periacetabular osteotomy to demonstrate the clinical outcomes for patients with varying amounts of dysplasia and arthritis. From these results, a probability-of-failure analysis was conducted to predict the likelihood of hip preservation and to improve surgical decision-making. Of the 189 hips (in 157 patients) that were treated with periacetabular osteotomy by a single surgeon from May 1991 to September 1998, thirty-one had diagnoses other than developmental hip dysplasia and twenty-three were lost to follow-up. The remaining 135 hips (in 109 patients) were retrospectively reviewed at an average of nine years. Hips were evaluated with use of the pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index postoperatively as well as with radiographs that were made preoperatively and at one and more than five years postoperatively. Osteotomy failure was defined as a pain score of ≥10 or the need for total hip arthroplasty. One hundred and two hips (76%) remained preserved at an average of nine years, with an average Western Ontario and McMaster Universities pain score of 2.4 of 20. Thirty-three hips (24%) met the failure criteria: seventeen underwent arthroplasty at an average of 6.1 years after the osteotomy, and sixteen had a postoperative pain score of ≥10. Kaplan-Meier analysis with arthroplasty as the end point revealed a survival rate of 96% (95% confidence interval, 93% to 99%) at five years and 84% (95% confidence interval, 77% to 90%) at ten years. Complications occurred in twenty hips. Fifteen hips (11%) were treated with a subsequent arthroscopy because

  20. A technique for sequential leaching of coal and fly ash resulting in good recovery of trace elements.

    Science.gov (United States)

    Norris, Pauline; Chen, Chien-Wei; Pan, Wei-Ping

    2010-03-17

    Coal and fly ash contain many elements. These elements exist in different forms which may change throughout the coal combustion process. There are several processes, including X-ray techniques and leaching techniques by which studies have attempted to assess the form of a particular element in a sample. This work focuses on determining the leachability of selected elements sequentially leached in four extraction solutions: water, 1M ammonium acetate, 3M hydrochloric acid and 50% hydrofluoric acid. The emphasis is on evaluating the steps involved in the leaching process with the mass recovery for each element being the basis for evaluation. The total amount of each element that will leach out under the given extraction condition is presented as a fraction of the total present in the material. The materials evaluated were NIST coal and fly ash standards. The elements measured in this study include aluminum, barium, beryllium, calcium, chromium, cobalt, iron, magnesium, manganese, nickel, potassium, sodium, strontium, vanadium and zinc.

  1. Application of the {sup 210}Pb-dating technique to evaluate environmental changes resulting from recent human activities

    Energy Technology Data Exchange (ETDEWEB)

    Jenkinson, A.V.; Chisari, R.; Farrar, Y.J.; Heijnis, H.; McOrist, G.D. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia); Hallegraeff, G. [University of Tasmania, Tasmania, (Australia). Department of Plant Science; Hughes, M.; Napoli, M. [University of Sydney, Sydney, NSW (Australia). Department of Geology and Geophysics; James, J.M. [University of Sydney, NSW, (Australia). School of Chemistry; McMinn, A.; Thomson, P. [University of Tasmania, Tasmania, (Australia). Institute of Antartic and Southern Ocean Studies; Smith, J.D.; Tinker, R.A. [University of Melbourne, Parkville, VIC (Australia). School of Chemistry, Marine Chemistry Laboratory

    1997-10-01

    The {sup 210}Pb-dating technique has shown particular promise for the study of recent environmental change by enabling the establishment of chronologies for contemporary environmental processes. In this paper two case studies are discussed. Case Study (1) looks at trace element and heavy metal levels in the estuaries of the Georges River and the Hacking River which are partly located in suburban Sydney and Case Study (2) looks at blooms of the toxic dinoflagellate Gymnodinium catenatum which were first observed in Tasmanian waters, principally the Huon and Derwent Rivers in 1980. In both cases the {sup 210}Pb dating technique has been used to establish the sequence of sediment deposition in order to associate an age to the sediment layer which contains the entity under investigation 7 refs., 5 figs.

  2. Sphincter-Sparing Surgery in Patients with Low-Lying Rectal Cancer: Techniques, Oncologic Outcomes, and Functional Results

    OpenAIRE

    Bordeianou, Liliana; Maguire, Lillias Holmes; Alavi, Karim; Sudan, Ranjan; Wise, Paul E.; Kaiser, Andreas M

    2014-01-01

    Background Rectal cancer management has evolved into a complex multimodality approach with survival, local recurrence, and quality of life parameters being the relevant endpoints. Surgical treatment for low rectal cancer has changed dramatically over the past 100 years. Discussion Abdominoperineal resection, once the standard of care for all rectal cancers, has become much less frequently utilized as surgeons devise and test new techniques for preserving the sphincters, maintaining continuity...

  3. Nail Braces as an Alternative Treatment for Ingrown Toenails: Results From a Comparison With the Winograd Technique.

    Science.gov (United States)

    Guler, Olcay; Tuna, Hamide; Mahirogullari, Mahir; Erdil, Mehmet; Mutlu, Serhat; Isyar, Mehmet

    2015-01-01

    Ingrown toenails are one of the most frequent nail disorders and can be treated with conservative or surgical approaches. Although discovered a long time ago, the available data are still very limited on the potential effectiveness of nail braces for ingrown toenail treatment. In the present retrospective study, we compared nail braces with surgical wedge excision using the Winograd technique with respect to the time to return to work, recurrence, interval to recurrence, and patient satisfaction. A total of 159 patients were divided into the nail brace (n = 74; mean age 29.51 ± 8.48 years) and Winograd technique (n = 85; mean age 26.95 ± 8.06 years) groups. In the nail brace group, the mean time to return to work (4.15 ± 1.07 days) was significantly shorter than that in the Winograd technique group (13.8 ± 2.26 days; p .05). A statistically significant difference was observed in the mean interval to recurrence (12.46 ± 1.60 versus 13.24 ± 2.48 months, respectively; p = .031). The progression-free follow-up periods for the nail brace and Winograd technique groups were 15.45 ± 0.22 months (95% confidence interval 15.02 to 15.88) and 17.18 ± 0.29 months (95% confidence interval 16.61 to 17.84), respectively. We have concluded that the use of nail braces is an appropriate alternative treatment of ingrown toenails with high patient satisfaction, fast recovery times, and a low recurrence rate.

  4. Excimer laser "corneal shaping": a new technique for customized trephination in penetrating keratoplasty. First experimental results in rabbits.

    Science.gov (United States)

    Schmitz, Klaus; Schreiber, Wolfram; Behrens-Baumann, Wolfgang

    2003-05-01

    The aim of the presented experimental work was to develop a technique for congruent trephination of donor and recipient corneas in free form using a 193-nm excimer laser and to study the clinical follow-up after the application of the technique in a rabbit model. In 12 New Zealand White rabbits homologous penetrating keratoplasty was performed. Trephination of donor buttons and recipient beds was achieved in six animals by conventional mechanical trephination and in six by excimer laser trephination with a guided laser beam in a non-circular geometry. The surgical procedure and its applicability to human subjects were evaluated and the postoperative clinical course was followed for 6 months. The surgical procedure of full-thickness excimer laser trephination could be performed reproducibly in the animal model both for dissection of the donor buttons and for preparation of the recipient beds. Keratoplasty was performed with kidney-shaped transplants after trephination in free form with the guided laser beam. Postoperative clinical follow-up did not show any differences between the two trephination groups that could be related to the applied trephination technique. After 6 months we observed well-adapted and clear corneal grafts, kidney-shaped in the excimer trephination group and circular in the mechanical trephination group. No side effects on the crystalline lens and the central retina could be clinically observed following excimer laser trephination. We present the first experimental study of keratoplasty with freely selected transplant geometry and perfect congruence of donor button and recipient bed. The application of this technique in certain corneal disorders in humans will offer improved treatment options in the future.

  5. A new volumetric CT machine for dental imaging based on the cone-beam technique: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Mozzo, P. [Dept. of Medical Physics, University Hospital, Verona (Italy); Procacci, C.; Tacconi, A.; Tinazzi Martini, P.; Bergamo Andreis, I.A. [Dept. of Radiology, University Hospital, Verona (Italy)

    1998-12-01

    The objective of this paper is to present a new type of volumetric CT which uses the cone-beam technique instead of traditional fan-beam technique. The machine is dedicated to the dento-maxillo-facial imaging, particularly for planning in the field of implantology. The main characteristics of the unit are presented with reference to the technical parameters as well as the software performance. Images obtained are reported as various 2D sections of a volume reconstruction. Also, measurements of the geometric accuracy and the radiation dose absorbed by the patient are obtained using specific phantoms. Absorbed dose is compared with that given off by spiral CT. Geometric accuracy, evaluated with reference to various reconstruction modalities and different spatial orientations, is 0.8-1 % for width measurements and 2.2 % for height measurements. Radiation dose absorbed during the scan shows different profiles in central and peripheral axes. As regards the maximum value of the central profile, dose from the new unit is approximately one sixth that of traditional spiral CT. The new system appears to be very promising in dento-maxillo-facial imaging and, due to the good ratio between performance and low cost, together with low radiation dose, very interesting in view of large-scale use of the CT technique in such diagnostic applications. (orig.) With 10 figs., 3 tabs., 15 refs.

  6. Refinement of the free radial forearm flap reconstructive technique after resection of large oropharyngeal malignancies with excellent functional results.

    Science.gov (United States)

    Moerman, Mieke; Vermeersch, Hubert; Van Lierde, Kristiane; Fahimi, Hossein; Van Cauwenberge, Paul

    2003-09-01

    Wide resection of oropharyngeal malignancies implicates the risk of velopharyngeal insufficiency, which can cause nasal regurgitation and hypernasality. A meticulous reconstruction is necessary to avoid impairment and handicap in deglutition and speech. In the classic reconstructive techniques for large oropharyngeal defects, functional outcome only regards deglutition. We also focus on nasality, because hypernasality often occurs as a consequence in this type of reconstruction. In four patients, the surgical defect is closed with a free radial forearm flap sutured to the posterior side of the hard palate, thus imitating a caudally based pharyngeal flap. Speech is assessed by an independent speech pathologist, perceptually and acoustically. Deglutition is evaluated by a questionnaire and videofluoroscopy. All patients had normal food intake. They did not report alterations in speech quality or verbal communication. Perceptual evaluation of articulation, voice, and nasality was optimal. Objective measurements with acoustical analysis and nasality scores confirmed the excellent functional outcome. Videofluoroscopy showed an unimpaired bolus transport with a complete velopharyngeal closure and optimal oral and pharyngeal clearance times. This meticulous reconstructive technique ensures an excellent functional outcome. The absence of nasality, in particular, proves the value of this refinement. The technique allows wide surgical margins and complete velopharyngeal closure. Copyright 2003 Wiley Periodicals, Inc. Head Neck 25: 772-777, 2003

  7. Optical mammography: a new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: preliminary results with radiologic-pathologic correlation.

    Science.gov (United States)

    Athanasiou, Alexandra; Vanel, Daniel; Fournier, Laure; Balleyguier, Corinne

    2007-02-28

    The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640 nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging-histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (<10 mm) infiltrating malignant lesions and ductal carcinoma in situ (DCIS). False positive results were seen in benign proliferative lesions. Dynamic optical breast imaging is a novel, low-cost, non-invasive technique yielding a new type of information about the physiology of breast lesions. Absorption is due to haemoglobin and its products, therefore reflecting the angiogenic status of breast tumours.

  8. Optical mammography: a new technique for visualizing breast lesions in women presenting non palpable BIRADS 4–5 imaging findings: preliminary results with radiologic–pathologic correlation

    Science.gov (United States)

    Vanel, Daniel; Fournier, Laure; Balleyguier, Corinne

    2007-01-01

    The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4–5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640 nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging–histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (<10 mm) infiltrating malignant lesions and ductal carcinoma in situ (DCIS). False positive results were seen in benign proliferative lesions. Dynamic optical breast imaging is a novel, low-cost, non-invasive technique yielding a new type of information about the physiology of breast lesions. Absorption is due to haemoglobin and its products, therefore reflecting the angiogenic status of breast tumours. PMID:17339139

  9. Chronic pain after inguinal hernia repair with the ONSTEP versus the Lichtenstein technique, results of a double-blinded multicenter randomized clinical trial

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Burcharth, Jakob; Fonnes, Siv;

    2016-01-01

    PURPOSE: The open new simplified totally extraperitoneal (ONSTEP) technique for the repair of inguinal hernia was presented some years ago with promising initial results regarding chronic pain. We conducted a randomized clinical trial investigating the ONSTEP technique versus the Lichtenstein...... participants with primary unilateral hernias, having surgical repair of their hernia at one of five participating general surgical departments. At surgery, participants were allocated (1:1) to the ONSTEP or the Lichtenstein technique for inguinal hernia repair. Participants were followed up with questionnaires...... was not seen in the ONSTEP group. CONCLUSION: The ONSTEP technique was not superior to the Lichtenstein technique regarding chronic pain following repair of primary inguinal hernias in males. TRIAL REGISTRATION: https://clinicaltrials.gov NCT01753219....

  10. In-office insertion of a miniaturized insertable cardiac monitor: Results from the Reveal LINQ In-Office 2 randomized study.

    Science.gov (United States)

    Rogers, John D; Sanders, Prashanthan; Piorkowski, Christopher; Sohail, M Rizwan; Anand, Rishi; Crossen, Karl; Khairallah, Farhat S; Kaplon, Rachelle E; Stromberg, Kurt; Kowal, Robert C

    2017-02-01

    Recent miniaturization of an insertable cardiac monitor (ICM) may make it possible to move device insertion from a hospital to office setting. However, the safety of this strategy is unknown. The primary objective was to compare the safety of inserting the Reveal LINQ ICM in an office vs a hospital environment. Ancillary objectives included summarizing device- and procedure-related adverse events and responses to a physician questionnaire. Five hundred twenty-one patients indicated for an ICM were randomized (1:1 ratio) to undergo ICM insertion in a hospital or office environment at 26 centers in the United States in the Reveal LINQ In-Office 2 study (ClinicalTrials.gov identifier NCT02395536). Patients were followed for 90 days. ICM insertion was successful in all 482 attempted patients (office: 251; hospital: 231). The untoward event rate (composite of unsuccessful insertion and ICM- or insertion-related complications) was 0.8% (2 of 244) in the office and 0.9% (2 of 227) in the hospital (95% confidence interval, -3.0% to 2.9%; 5% noninferiority: P office and 4.4% (10 of 227) of hospital insertions (95% confidence interval [office minus inhospital rates], -5.8% to 1.9%; 5% noninferiority: P office vs a hospital, there were fewer delays >15 minutes (16% vs 35%; P office location "very convenient" more frequently than the hospital location (85% vs 27%; P < .001). The safety profile for the insertion of the Reveal LINQ ICM is excellent irrespective of insertion environment. These results may expand site of service options for LINQ insertion. Copyright © 2016 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  11. FIXATION OF FRACTURES OF THE DISTAL EXTREMITY OF THE RADIUS USING THE MODIFIED KAPANDJI TECHNIQUE: EVALUATION OF THE RADIOLOGICAL RESULTS.

    Science.gov (United States)

    Neto, Antonio Piva; Lhamby, Fabio Colla

    2011-01-01

    To demonstrate a simple and efficacious option for treating fractures of the distal extremity of the radius using Kirschner wires. Between September 2008 and April 2009, 48 patients with fractures of the distal extremity of the radius, classified as A3 according to the AO classification, were treated surgically using a modification of the Kapandji technique. Out of the 48 wrists operated, 42 (87.5%) presented postoperative measurements within the acceptable limits. We used the parameters of McQuenn and Caspers who considered that the radial angulation should be wider than 19° and the volar angulation should be narrower than -12°. All the postoperative volar inclination measurements were narrower than -3°. The mean preoperative radial inclination was 13.14° and the mean postoperative value was 21.18°. The mean preoperative volar inclination was 28.75° and the mean postoperative value was 3.31°. The mean preoperative radial height was 5.25 mm and the mean postoperative value was 9.48 mm. The technique described here had excellent stability for treating fractures of the distal extremity of the radius classified as A3. It was easy to implement and minimally invasive, with minimal surgical complications, and it was inexpensive.

  12. Evaluation of coblation lingual tonsil removal technique for obstructive sleep apnea in Asians: preliminary results of surgical morbidity and prognosticators.

    Science.gov (United States)

    Wee, Jee Hye; Tan, Kenglu; Lee, Woo-Hyun; Rhee, Chae-Seo; Kim, Jeong-Whun

    2015-09-01

    Retroglossal obstruction is one of the etiologies causing obstructive sleep apnea (OSA) and can be addressed by removing some tissues of the tongue base. However, because of its deep-seated location, its surgical removal is still challenging. Although coblation technique has been introduced, its efficacy and morbidity need further evaluation, particularly in Asians. This study aimed to assess its safety and effectiveness and to identify outcome prognosticators. Forty-seven OSA patients who underwent coblation lingual tonsil removal were included. Retroglossal obstruction was confirmed by drug-induced sleep videofluoroscopy. Attended full-night polysomnography was performed twice; before and 6 months after surgery in 27 patients. The tongue base was fully exposed with three deep-seated traction sutures, visualized with a 30° or 70° endoscope, and ablated using a coblator. Surgical success was defined with postoperative apnea hypopnea index (AHI) 50 %. Postoperative morbidities were evaluated. Demographic and polysomnographic parameters between success and failure groups were compared. None of the patients had immediate postoperative hemorrhage. Postoperatively, one patient had delayed hemorrhage and one patient severe respiratory difficulty. Taste loss, tongue dysmotility, dental injury or severe oropharyngeal stricture were absent. A mean AHI decreased from 37.7 ± 18.6 to 18.7 ± 14.8/h (P Coblation lingual tonsil removal technique showed minimal morbidity and favorable outcome in Koreans. The surgical outcome might be associated with the severity of single respiratory events.

  13. A statistical approach for site error correction in lightning location networks with DF/TOA technique and its application results

    Science.gov (United States)

    Lu, Tao; Chen, Mingli; Du, Yaping; Qiu, Zongxu

    2017-02-01

    Lightning location network (LLN) with DF/TOA (direction-finder/time-of-arrival) combined technique has been widely used in the world. However, the accuracy of the lightning data from such LLNs has still been restricted by "site error", especially for those detected only by two DF/TOA sensors. In this paper we practice a statistical approach for evaluation and correction of "site error" for DF/TOA type LLN based on its lightning data. By comparing lightning locations recorded by at least 4 sensors between DF and TOA techniques, the spatial characteristics of "site error" for each sensor in the network can be obtained. The obtained "site error" then can be used to improve the accuracy of lightning locations especially those recorded by only 2 sensors. With this approach, the "site error" patterns for 23 sensors in Yunnan LLN are obtained. The features of these site error patterns are in good consistency with those in literature. Significant differences in lightning locations before and after "site error" corrections indicate that the proposed approach works effectively.

  14. A field technique for rapid lithological discrimination and ore mineral identification: Results from Mamandur Polymetal Deposit, India

    Indian Academy of Sciences (India)

    D Ramakrishnan; M Nithya; K D Singh; Rishikesh Bharti

    2013-02-01

    This work illustrates the efficiency of field spectroscopy for rapid identification of minerals in ore body, alteration zone and host rocks. The adopted procedure involves collection of field spectra, their processing for noise, spectral matching and spectral un-mixing with selected library end-members. Average weighted spectral similarity and effective peak matching techniques were used to draw end-members from library. Constrained linear mixture modelling technique was used to convolve end-member spectra. Linear mixture model was optimized based on root mean square error between field- and modelled-spectra. Estimated minerals and their abundances were subsequently compared with conventional procedures such as petrography, X-ray diffraction and X-ray fluorescence for accuracy assessment. The mineralized zone is found to contain azurite, galena, chalcopyrite, bornite, molybdenite, marcacite, gahnite, hematite, goethite, anglesite and malachite. The alteration zone contains chlorite, kaolinite, actinolite and mica. These mineral assemblages correlate well with the petrographic measurements (2 = 0.89). Subsequently, the bulk chemistry of field samples was compared with spectroscopically derived cumulative weighted mineral chemistry and found to correlate well (2 = 0.91–0.98) at excellent statistical significance levels (90–99%). From this study, it is evident that field spectroscopy can be effectively used for rapid mineral identification and abundance estimation.

  15. The arcuate fold-and-thrust belt of northern Taiwan: Results of a two-stage rotation revealed from a paleomagnetic study

    Science.gov (United States)

    Sonnette, Lionel; Lee, Jian-Cheng; Horng, Chorng-Shern

    2017-10-01

    The Taiwan orogen is the result of the collision of the Luzon Volcanic Arc pushed northwestward by the Philippine Sea Plate against the Chinese Continental Margin since the Late Miocene and is still uplifting nowadays. The fold-and-thrust belt in northern Taiwan shows an arcuate shape from SW to NE: the strike of the main tectonic structures changes from N 0 ° E to N 70 ° E. Such curvature has not yet been properly interpreted so far. In this study we used paleomagnetic analyses to decipher the tectonic evolution along the fold-and-thrust belt in northern Taiwan, which reveals complex magnetization patterns both in ante-folding and post-folding formations. We also interpret that the fold-and-thrust belt in northern Taiwan has experienced two main rotational events: a 30 - 60 ± 14 ° clockwise rotation followed by a 30 ± 7 ° counterclockwise rotation during the ages of 4.6-1.5 Ma.

  16. Use of combined microscopic and spectroscopic techniques to reveal interactions between uranium and Microbacterium sp. A9, a strain isolated from the Chernobyl exclusion zone

    Energy Technology Data Exchange (ETDEWEB)

    Theodorakopoulos, Nicolas [CEA, DSV, IBEB, SBVME, LIPM, F-13108 Saint-Paul-lez-Durance (France); CNRS, UMR 7265, F-13108 Saint-Paul-lez-Durance (France); Université d' Aix-Marseille, F-13108 Saint-Paul-lez-Durance (France); IRSN/PRP-ENV/SERIS/L2BT, bat 183, B.P. 3, F-13115 Saint Paul-lez-Durance (France); Chapon, Virginie [CEA, DSV, IBEB, SBVME, LIPM, F-13108 Saint-Paul-lez-Durance (France); CNRS, UMR 7265, F-13108 Saint-Paul-lez-Durance (France); Université d' Aix-Marseille, F-13108 Saint-Paul-lez-Durance (France); Coppin, Fréderic; Floriani, Magali [IRSN/PRP-ENV/SERIS/L2BT, bat 183, B.P. 3, F-13115 Saint Paul-lez-Durance (France); Vercouter, Thomas [CEA, DEN, DANS, DPC SEARS, LANIE, F-91191 Gif-Sur-Yvette Cedex (France); Sergeant, Claire [Univ Bordeaux, CENBG, UMR5797, F-33170 Gradignan (France); CNRS, IN2P3, CENBG, UMR5797, F-33170 Gradignan (France); Camilleri, Virginie [IRSN/PRP-ENV/SERIS/L2BT, bat 183, B.P. 3, F-13115 Saint Paul-lez-Durance (France); Berthomieu, Catherine [CEA, DSV, IBEB, SBVME, LIPM, F-13108 Saint-Paul-lez-Durance (France); CNRS, UMR 7265, F-13108 Saint-Paul-lez-Durance (France); Université d' Aix-Marseille, F-13108 Saint-Paul-lez-Durance (France); Février, Laureline, E-mail: laureline.fevrier@irsn.fr [IRSN/PRP-ENV/SERIS/L2BT, bat 183, B.P. 3, F-13115 Saint Paul-lez-Durance (France)

    2015-03-21

    Highlights: • Microbacterium sp. A9 develops various detoxification mechanisms. • Microbacterium sp. A9 promotes metal efflux from the cells. • Microbacterium sp. A9 releases phosphate to prevent uranium entrance in the cells. • Microbacterium sp. A9 stores U intracellularly as autunite. - Abstract: Although uranium (U) is naturally found in the environment, soil remediation programs will become increasingly important in light of certain human activities. This work aimed to identify U(VI) detoxification mechanisms employed by a bacteria strain isolated from a Chernobyl soil sample, and to distinguish its active from passive mechanisms of interaction. The ability of the Microbacterium sp. A9 strain to remove U(VI) from aqueous solutions at 4 °C and 25 °C was evaluated, as well as its survival capacity upon U(VI) exposure. The subcellular localisation of U was determined by TEM/EDX microscopy, while functional groups involved in the interaction with U were further evaluated by FTIR; finally, the speciation of U was analysed by TRLFS. We have revealed, for the first time, an active mechanism promoting metal efflux from the cells, during the early steps following U(VI) exposure at 25 °C. The Microbacterium sp. A9 strain also stores U intracellularly, as needle-like structures that have been identified as an autunite group mineral. Taken together, our results demonstrate that this strain exhibits a high U(VI) tolerance based on multiple detoxification mechanisms. These findings support the potential role of the genus Microbacterium in the remediation of aqueous environments contaminated with U(VI) under aerobic conditions.

  17. Arthroscopic rotator cuff repair: analysis of technique and results at 2- and 3-year follow-up.

    Science.gov (United States)

    Tauro, J C

    1998-01-01

    We present 53 patients who underwent arthroscopic rotator cuff repair and had a minimum of 2-year follow-up. Most tears were avulsions of the supraspinatus from the greater tuberosity, some with associated longitudinal tears. Longitudinal tears were repaired with a side-to-side suturing technique. Avulsion tears from the tuberosity were repaired using nonretrievable suture anchors. Traditional open-mobilization techniques, such as elevating the cuff off the glenoid neck and scapular fossa, and cutting the coraco-humeral ligament, were performed arthroscopically as needed. All repairs were performed using O-PDS or 1-PDS suture and a 7-mm suture punch for suture delivery. Both simple and mattress suture configurations were used. An anterolateral operative portal was used in most cases. A modified UCLA rating system that included additional points for abduction range of motion and strength was adapted for clinical evaluation in this study (maximum score, 45 points). The average preoperative rating was 17 (range, 9 to 26). The average postoperative rating was 41 (range, 16 to 45). There were 36 excellent (41 to 45 points), 13 good (36 to 40 points), 1 fair (30 to 35 points), and 3 poor (mobilization is relatively simple and has allowed us to repair larger tears. Based on our experience, arthroscopic rotator cuff repair is technically achievable and a superior alternative in selected cases for an experienced shoulder arthroscopist. Patients who underwent arthroscopic repairs had less scarring and shorter hospital stays and, we believe, less postoperative pain and easier rehabilitation compared with open repairs.

  18. Short- and midterm results of the fascia suture technique for closure of femoral artery access sites after endovascular aneurysm repair.

    Science.gov (United States)

    Montán, Carl; Lehti, Leena; Holst, Jan; Björses, Katarina; Resch, Timothy A

    2011-12-01

    To evaluate the midterm outcomes and potential risk factors associated with the fascia suture technique (FST) for closure of femoral artery access sites after percutaneous endovascular aneurysm repair (EVAR). Between April 2007 and April 2008, 100 consecutive EVAR cases were evaluated retrospectively. A third of the procedures were emergent (16 ruptured aneurysms). Of the 187 femoral access sites, 160 (85.5%) were closed by the FST as a first choice. Pre- and postoperative chart and imaging data were collected from computerized medical records for analysis of demographics and the rate of complications (bleeding, infection, thrombosis, pseudoaneurysms, and stenosis). Preoperative risk factors for FST failure were analyzed with regard to obesity (based on the subcutaneous fat layer), plaque at the femoral access site, and stenosis based on the pre- and 1-year postoperative computed tomography scans. Of the 160 FST closures, 146 (91.3%) were technically successful. The 14 (8.8%) technical failures were converted to open cutdown intraoperatively because of bleeding (11, 6.8%), inadequate limb perfusion (2, 1.2%), and a broken guidewire (1, 0.6%). Two (1.2%) pseudoaneurysms required surgical repair after 2 weeks. Data from the 1-year follow-up showed no signs of increased stenosis, thrombosis, or formation of plaque. Nine small (<1 cm(3)) pseudoaneurysms were detected and managed conservatively. No preoperative risk factors were associated with FST failure. The fascia suture technique seems to be safe, effective, and simple to use for closing percutaneous access sites after EVAR. Complications are rare, and the outcome is not affected by obesity, femoral calcification, or femoral artery stenosis.

  19. A novel, integrated PET-guided MRS technique resulting in more accurate initial diagnosis of high-grade glioma.

    Science.gov (United States)

    Kim, Ellen S; Satter, Martin; Reed, Marilyn; Fadell, Ronald; Kardan, Arash

    2016-06-01

    Glioblastoma multiforme (GBM) is the most common and lethal malignant glioma in adults. Currently, the modality of choice for diagnosing brain tumor is high-resolution magnetic resonance imaging (MRI) with contrast, which provides anatomic detail and localization. Studies have demonstrated, however, that MRI may have limited utility in delineating the full tumor extent precisely. Studies suggest that MR spectroscopy (MRS) can also be used to distinguish high-grade from low-grade gliomas. However, due to operator dependent variables and the heterogeneous nature of gliomas, the potential for error in diagnostic accuracy with MRS is a concern. Positron emission tomography (PET) imaging with (11)C-methionine (MET) and (18)F-fluorodeoxyglucose (FDG) has been shown to add additional information with respect to tumor grade, extent, and prognosis based on the premise of biochemical changes preceding anatomic changes. Combined PET/MRS is a technique that integrates information from PET in guiding the location for the most accurate metabolic characterization of a lesion via MRS. We describe a case of glioblastoma multiforme in which MRS was initially non-diagnostic for malignancy, but when MRS was repeated with PET guidance, demonstrated elevated choline/N-acetylaspartate (Cho/NAA) ratio in the right parietal mass consistent with a high-grade malignancy. Stereotactic biopsy, followed by PET image-guided resection, confirmed the diagnosis of grade IV GBM. To our knowledge, this is the first reported case of an integrated PET/MRS technique for the voxel placement of MRS. Our findings suggest that integrated PET/MRS may potentially improve diagnostic accuracy in high-grade gliomas.

  20. Application of a Shape-Memory Alloy Concentrator in Displaced Patella Fractures: Technique and Long-Term Results.

    Science.gov (United States)

    Zhang, Yuntong; Wang, Panfeng; Xia, Yan; Zhou, Panyu; Xie, Yang; Xu, Shuogui; Zhang, Chuncai

    2017-02-01

    Operative treatment is usually recommended in displaced patella fractures. Several techniques have been advocated for internal fixation of patella fractures. Despite the relatively good clinical outcomes that have been demonstrated in many studies, postoperative morbidities such as fixation failure, nonunion, infection, and knee stiffness are not uncommon. We present a new alternative treatment technique for displaced patellar fractures. Between April 1995 and May 2005, we used the Nitinol Patella Concentrator (NTPC) to treat 156 consecutive patients with displaced patellar fractures. Injuries arose from vehicular accidents in 56 (35.9%) cases, direct falls onto the knee in 85 (54.5%) cases, and sports injuries in 15 (9.6%) cases. The mean patient age was 46.3 years (range, 25-77 years). Clinical assessments were made using the Böstman knee score and the MOS SF-36 questionnaire (Medical Outcomes Study 36-item short-form health survey), which were both recorded at the final follow-up visit. The mean follow-up was 7.3 years (range, 6-17 years). At the final follow-up, the Böstman knee scores were excellent in 88 cases (28-30), good in 55 (20-27), and unsatisfactory in 13 (<20). According to the MOS SF-36 evaluation, the average score was 84.5 (range, 62-91). Treatment of patellar fracture with the NTPC not only may serve as an effective and rigid fixation method in multifragmented displaced and inferior pole fractures, but also may provide continuous concentrative compression during the osseous healing process. Thus, use of the NTPC may help restore the functional integrity of the extensor mechanism and permit early rehabilitation with a lower incidence of postoperative complications. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  1. Regional glacier changes in the Ötztal Alps (Tyrol, Austria) - Results from different remote sensing techniques

    Science.gov (United States)

    Klug, Christoph; Rieg, Lorenzo; Sailer, Rudolf

    2017-04-01

    Climate change will pose a variety of challenges in the future, with global sea level rise among the most important ones. Out of all contributions to sea level rise, the contribution from glaciers is the one with the highest uncertainty. This is mainly because only very few and not necessarily representative glaciers are measured regularly. Among others, this limits the validation of extrapolation models. On a regional scale, remote sensing data offer several possibilities for the mapping and monitoring of glaciers. Especially with the advent of very high resolution data, new possibilities can be exploited. The monitoring of glacier area, the calculation of the geodetic glacier mass balances and the tracking of changes in the seasonal snow and firn bodies of glaciers on a regional scale can not only help to enhance the spatial, but also the temporal coverage of observations. The Ötztal Alps in Tyrol, Austria have been a research focus for the University of Innsbruck for several decades. Ongoing glaciological field measurements at two reference glaciers (Hintereisferner and Kesselwandferner) and data from different remote sensing techniques provide a valuable basis for a variety of research. The presented study analyses high-resolution airborne laser scanning (ALS) data, with more than 10 years of annual campaigns on Hintereisferner (2001-2013) and two campaigns covering all of the Ötztal Alps (2006 and 2010) in combination with orthoimages and optical satellite data. Furthermore Pléiades tri-stereo data (2015 and 2016) are available to calculate very high resolution and high quality digital terrain models (DTM). These DTM can be used to extend the time series in combination with the DTM based on ALS data and enable the calculation of the geodetic glacier mass balance for over 150 glaciers within the study area. Furthermore, the optical information (ALS intensity, orthoimages and optical satellite data) is used for surface classification in order to monitor the

  2. Intravascular ultrasound guidance of percutaneous coronary intervention in ostial chronic total occlusions: a description of the technique and procedural results.

    Science.gov (United States)

    Ryan, Nicola; Gonzalo, Nieves; Dingli, Philip; Cruz, Oscar Vedia; Jiménez-Quevedo, Pilar; Nombela-Franco, Luis; Nuñez-Gil, Ivan; Trigo, María Del; Salinas, Pablo; Macaya, Carlos; Fernandez-Ortiz, Antonio; Escaned, Javier

    2017-02-14

    Inability to cross the lesion with a guidewire is the most common reason for failure in percutaneous revascularization (PCI) of chronic total occlusions (CTOs). An ostial or stumpless CTO is an acknowledged challenge for CTO recanalization due to difficulty in successful wiring. IVUS imaging provides the opportunity to visualize the occluded vessel and to aid guidewire advancement. We review the value of this technique in a single-centre experience of CTO PCI. This series involves 22 patients who underwent CTO-PCI using IVUS guidance for stumpless CTO wiring at our institution. CTO operators with extensive IVUS experience in non-CTO cases carried out all procedures. Procedural and outcome data was prospectively entered into the institutional database and a retrospective analysis of clinical, angiographic and technical data performed. 17 (77%) of the 22 procedures were successful. The mean age was 59.8 ± 11.5 years, and 90.9% were male. The most commonly attempted lesions were located in the left anterior descending 36.4% (Soon et al. in J Intervent Cardiol 20(5):359-366, 2007) and Circumflex artery (LCx) 31.8% (Mollet et al. in Am J Cardiol 95(2):240-243, 2005). Mean JCTO score was 3.09 ± 0.75 (3.06 ± 0.68, 3.17 ± 0.98 in the successful and failed groups respectively p = 0.35). The mean contrast volume was 378.7 ml ± 114.7 (389.9 ml ± 130.5, 349.2 ml ± 52.2 p = 0.3 in the successful and failed groups respectively). There was no death, coronary artery bypass grafting or myocardial infarction requiring intervention in this series. When the success rates were analyzed taking into account the date of adoption of this technique, the learning curve had no significant impact on CTO-PCI success. This series describes a good success rate in IVUS guided stumpless wiring of CTOs in consecutive patients with this complex anatomical scenario.

  3. Technical results of the French electricity supply industry 2002; Resultats techniques du secteur electrique en France 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    Provisional detailed results of power flows in France in 2002, with the operating context and international comparisons. This booklet presents provisional results, expressed in rounded values because of some estimated values. Data come from measures made by RTE, completed by various actors of the power system and by estimations made by RTE: general results France; operation outlook; energy flows; exchanges with foreign countries; French consumption; French generation; network operation; access to the transmission network; development over the past 15 years; international comparisons; terminology.

  4. Technical results of the power sector in France 2001; Resultats techniques du secteur electrique en France 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Provisional detailed results of power flows in France in 2002, with the operating context and international comparisons. This booklet presents provisional results, expressed in rounded values because of some estimated values. Data come from measures made by RTE, completed by various actors of the power system and by estimations made by RTE: general results France; operation outlook; energy flows; exchanges with foreign countries; French consumption; French generation; network operation; access to the transmission network; development over the past 15 years; international comparisons; terminology.

  5. Pulley Reconstruction As Part of the Surgical Treatment for de Quervain Disease: Surgical Technique with Medium-Term Results.

    Science.gov (United States)

    van der Wijk, Jacobien; Goubau, Jean F; Mermuys, Koen; van Hoonacker, Petrus; Vanmierlo, Bert; Kerckhove, Diederick; Berghs, Bart

    2015-08-01

    Background Simple decompression of the first extensor compartment is commonly used for treating de Quervain disease, with the possible complication of subluxation of the tendons of the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) over the radial styloid. To prevent this painful subluxation of the tendons, several methods of reconstructing the pulley have been proposed. Questions/Purposes The purpose of our study was to evaluate a new technique for reconstructing the first extensor compartment following a release for de Quervain disease. Patients and Methods A retrospective study (mean length 40.4 months) was performed in 45 patients. The outcome assessment involved two different questionnaires and ultrasound evaluation of any tendon subluxation. Results None of the patients required reoperation for tendon instability or incomplete decompression of the first extensor compartment. Two patients experienced clicking around the radial styloid after surgery. This was not related to the amount of volar migration of the tendons. Conclusions We believe the reconstruction proposed here is an effective method of preventing painful subluxation of the APL and EPB following a release of the first extensor compartment.

  6. Outcome of arthroscopic subscapularis tendon repair: Are the results improving with improved techniques and equipment?: A retrospective case series

    Directory of Open Access Journals (Sweden)

    G R Arun

    2016-01-01

    Conclusion: At a median followup of 2 years, 95% of patients had a good to excellent result after an arthroscopic subscapularis tendon repair. We conclude that the midterm results show that arthroscopic subscapularis repair remains a good option for the treatment of patients with subscapularis tendon repair.

  7. Embryonic NOTES thoracic sympathectomy for palmar hyperhidrosis: results of a novel technique and comparison with the conventional VATS procedure.

    Science.gov (United States)

    Zhu, Li-Huan; Chen, Long; Yang, Shengsheng; Liu, Daoming; Zhang, Jixue; Cheng, Xianjin; Chen, Weisheng

    2013-11-01

    To avoid the disadvantages of chronic pain and chest wall paresthesia associated with video-assisted thoracic surgery (VATS) procedures, we developed a novel surgical technique for performing sympathectomy by embryonic natural orifice transumbilical endoscopic surgery (E-NOTES) with a flexible endoscope. In this study, we compared the outcomes of E-NOTES with conventional VATS thoracic sympathectomy on palmar hyperhidrosis. From January 2010 to April 2011, a total of 66 patients with severe palmar hyperhidrosis were treated with thoracic sympathectomy in our department. Thirty-four transumbilical thoracic sympathectomies were performed via a 5-mm umbilicus incision with ultrathin gastroscope, then compared with 32 conventional needlescopic thoracic sympathectomies. Retrospective statistical analysis of a prospectively collected group of patients was performed. There was no significant difference with regard to gender, mean age, body mass index, and length of hospital stay between the two groups. The operative time for E-NOTES thoracic sympathectomy was longer than that of VATS thoracic sympathectomy (56.4 ± 10.8 vs. 40.3 ± 6.5 min, p sympathectomy reported successful treatment of their palmar hyperhidrosis. Compensatory hyperhidrosis was noticed in 7 (20.1 %) and 6 (18.8 %) patients in the E-NOTES and VATS groups, respectively (p > 0.05). Postoperative pain and paresthesia were significantly reduced in the E-NOTES group at each time interval, and the aesthetic effect of the incision was superior in the E-NOTES group. Transumbilical-diaphragmatic thoracic sympathectomy is a safe and efficacious alternative to the conventional approach. This novel procedure can further reduce postoperative pain and chest wall paresthesia as well as afford maximum cosmetic benefits by hiding the surgical incision in the umbilicus.

  8. Geophysical techniques in the historical center of Venice (Italy): preliminary results from HVSR and multichannel analysis of surface waves

    Science.gov (United States)

    Trevisani, Sebastiano; Rocca, Michele; Boaga, Jacopo

    2014-05-01

    This presentation aims to outline the preliminary findings related to an extensive seismic survey conducted in the historical center of Venice, Italy. The survey was conducted via noninvasive and low-cost seismic techniques based on surface waves analysis and microtremor methods, mainly using single station horizontal to vertical spectral ratio techninques (HVSR) and multichannel analysis of surface waves in passive (ReMI) and active (MASW) configurations. The importance and the fragility of the cultural heritage of Venice, coupled with its peculiar geological and geotechnical characteristics, stress the importance of a good knowledge of its geological architecture and seismic characteristics as an opportunity to improve restoration and conservation planning. Even if Venice is located in a relatively low seismic hazard zone, a local characterization of soil resonance frequencies and surficial shear waves velocities could improve the planning of engineering interventions, furnishing important information on possible local effects related to seismic amplification and possible coupling within buildings and soil resonance frequencies. In the specific we collected more than 50 HVSR single station noise measurements and several passive and active multichannel analysis of surface waves located in the historical center. In this work we report the characteristics of the conducted seismic surveys (instrumentation, sampling geometry, etc.) and the preliminary findings of our analysis. Moreover, we discuss briefly the practical issues, mainly of logistic nature, of conducting this kind of surveys in a peculiar and crowed historical center as represented by Venice urban contest. Acknowledgments Instrumentation acquired in relation to the project co-financed by Regione Veneto, POR-CRO, FESR, 2007-2013, action 1.1.1. "Supporto ad attività di ricerca, processi e reti di innovazione e alla creazione di imprese in settori a elevato contenuto tecnologico"

  9. Transcription profile analysis reveals that zygotic division results in uneven distribution of specific transcripts in apical/basal cells of tobacco.

    Directory of Open Access Journals (Sweden)

    Ligang Ma

    Full Text Available BACKGROUND: Asymmetric zygotic division in higher plants results in the formation of an apical cell and a basal cell. These two embryonic cells possess distinct morphologies and cell developmental fates. It has been proposed that unevenly distributed cell fate determinants and/or distinct cell transcript profiles may be the underlying reason for their distinct fates. However, neither of these hypotheses has convincing support due to technical limitations. METHODOLOGY/PRINCIPAL FINDINGS: Using laser-controlled microdissection, we isolated apical and basal cells and constructed cell type-specific cDNA libraries. Transcript profile analysis revealed difference in transcript composition. PCR and qPCR analysis confirmed that transcripts of selected embryogenesis-related genes were cell-type preferentially distributed. Some of the transcripts that existed in zygotes were found distinctly existed in apical or basal cells. The cell type specific de novo transcription was also found after zygotic cell division. CONCLUSIONS/SIGNIFICANCE: Thus, we found that the transcript diversity occurs between apical and basal cells. Asymmetric zygotic division results in the uneven distribution of some embryogenesis related transcripts in the two-celled proembryos, suggesting that a differential distribution of some specific transcripts in the apical or basal cells may involve in guiding the two cell types to different developmental destinies.

  10. High-resolution, terrestrial radar velocity observations and model results reveal a strong bed at stable, tidewater Rink Isbræ, West Greenland

    Science.gov (United States)

    Bartholomaus, T. C.; Walker, R. T.; Stearns, L. A.; Fahnestock, M. A.; Cassotto, R.; Catania, G. A.; Felikson, D.; Fried, M.; Sutherland, D.; Nash, J. D.; Shroyer, E.

    2015-12-01

    At tidewater Rink Isbræ, on the central west coast of Greenland, satellite observations reveal that glacier velocities and terminus positions have remained stable, while the lowest 25 km have thinned 30 m since 1985. Over this same time period, other tidewater glaciers in central west Greenland have retreated, thinned and accelerated. Here we present field observations and model results to show that the flow of Rink Isbræ is resisted by unusually high basal shear stresses. Terrestrial radar interferometry (TRI) observations over 9 days in summer 2014 demonstrate weak velocity response to 4 km wide, full thickness calving events. Velocities at the terminus change by +/- 10% in response to rising and falling tides within a partial-width, 2.5-km-long floating ice tongue; however these tidal perturbations damp out within 2 km of the grounding line. Inversions for basal shear stress and force balance analyses together show that basal shear stresses in excess of 300 kPa support the majority of the driving stress at thick, steep Rink Isbræ. These observational and modeling results tell a consistent story in which a strong bed may limit the unstable tidewater glacier retreats observed elsewhere. Rink Isbræ has an erosion resistant quartzite bed with low fracture density. We hypothesize that this geology may play a major role in the bed strength.

  11. Comparative evaluation of the results of three techniques in the reconstruction of the anterior cruciate ligament, with a minimum follow-up of two years.

    Science.gov (United States)

    Cury, Ricardo de Paula Leite; Sprey, Jan Willem Cerf; Bragatto, André Luiz Lima; Mansano, Marcelo Valentim; Moscovici, Herman Fabian; Guglielmetti, Luiz Gabriel Betoni

    2017-01-01

    To compare the clinical results of the reconstruction of the anterior cruciate ligament by transtibial, transportal, and outside-in techniques. This was a retrospective study on 90 patients (ACL reconstruction with autologous flexor tendons) operated between August 2009 and June 2012, by the medial transportal (30), transtibial (30), and "outside-in" (30) techniques. The following parameters were assessed: objective and subjective IKDC, Lysholm, KT1000, Lachman test, Pivot-Shift and anterior drawer test. On physical examination, the Lachman test and Pivot-Shift indicated a slight superiority of the outside-in technique, but without statistical significance (p = 0.132 and p = 0.186 respectively). The anterior drawer, KT1000, subjective IKDC, Lysholm, and objective IKDC tests showed similar results in the groups studied. A higher number of complications were observed in the medial transportal technique (p = 0.033). There were no statistically significant differences in the clinical results of patients undergoing reconstruction of the anterior cruciate ligament by transtibial, medial transportal, and outside-in techniques.

  12. Trends in changes of elite sportswomen’ technique, specializing in 20 km race walk, considering rising of their sports results

    Directory of Open Access Journals (Sweden)

    Sovenko S.P.

    2015-04-01

    Full Text Available Purpose: on the base of bio-mechanical characteristics’ analysis determination of trends in technique’s changes of elite sportswomen, specializing in 20 kilometers’ race walk, with rising of their sport results. Material: the research covered 13 elite sportswomen, specializing in 20 kilometers’ race walk (396 measurements. Results: bio-mechanical characteristics of the best 20 kilometers’ race walk sportswomen at Ukrainian championships 2014-2015 have been elucidated. Comparative analysis of elite sportswomen, having different sport results, has been conducted. Conclusions: improvement of sportsmanship to world level (from 1:38:37 to 1:31:35 takes place at the account of increasing of step length to 1.10 m (S = 0,01; shortening of phase of single support X average = 0.26 sec.; S = 0.01 owing to reduction of shock absorption time to 0.08 sec.

  13. Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity.

    Science.gov (United States)

    Williams, Stephen R; Zies, Deborah; Mullegama, Sureni V; Grotewiel, Michael S; Elsea, Sarah H

    2012-06-08

    Haploinsufficiency of RAI1 results in Smith-Magenis syndrome (SMS), a disorder characterized by intellectual disability, multiple congenital anomalies, obesity, neurobehavioral abnormalities, and a disrupted circadian sleep-wake pattern. An inverted melatonin rhythm (i.e., melatonin peaks during the day instead of at night) and associated sleep-phase disturbances in individuals with SMS, as well as a short-period circadian rhythm in mice with a chromosomal deletion of Rai1, support SMS as a circadian-rhythm-dysfunction disorder. However, the molecular cause of the circadian defect in SMS has not been described. The circadian oscillator temporally orchestrates metabolism, physiology, and behavior largely through transcriptional modulation. Data support RAI1 as a transcriptional regulator, but the genes it might regulate are largely unknown. Investigation into the role that RAI1 plays in the regulation of gene transcription and circadian maintenance revealed that RAI1 regulates the transcription of circadian locomotor output cycles kaput (CLOCK), a key component of the mammalian circadian oscillator that transcriptionally regulates many critical circadian genes. Data further show that haploinsufficiency of RAI1 and Rai1 in SMS fibroblasts and the mouse hypothalamus, respectively, results in the transcriptional dysregulation of the circadian clock and causes altered expression and regulation of multiple circadian genes, including PER2, PER3, CRY1, BMAL1, and others. These data suggest that heterozygous mutation of RAI1 and Rai1 leads to a disrupted circadian rhythm and thus results in an abnormal sleep-wake cycle, which can contribute to an abnormal feeding pattern and dependent cognitive performance. Finally, we conclude that RAI1 is a positive transcriptional regulator of CLOCK, pinpointing a novel and important role for this gene in the circadian oscillator.

  14. X-ray microCT imaging technique reveals corm microstructures of an arctic-boreal cotton-sedge, Eriophorum vaginatum.

    Science.gov (United States)

    Bogart, Sarah J; Spiers, Graeme; Cholewa, Ewa

    2010-09-01

    X-ray computed tomography (CT), a non-destructive imaging technique, has recently been effectively applied to botanical research. In this study an X-ray microCT technique was developed to allow for anatomical study of the overwintering corms of Eriophorum vaginatum, an ecologically important sedge species in arctic tussock-tundra and boreal peatlands. Using a GE Medical MS8X-130 X-ray microCT scanner, optimal imaging parameters included scanning isolated corms at 80 k Vp and 100 microA with a 3500 ms exposure time and an isotropic voxel size of 10 microm. A Gaussian blur image filter with a blur radius (sigma) of two pixels was applied to the optimal dataset to improve visual detection and contrast of tissues while removing 99.2% of image noise. Using the developed X-ray microCT technique several undocumented anatomical characteristics of the corm were identified including the vascular connection between a parent corm and branching cormel and the 3D shape of sclereid clusters. The 3D structure of sclereid clusters was determined whereby the perimeter of their lance shape is greatly reinforced by sclereids with thicker secondary cell walls as compared to those of the interior of the cluster. The structure of sclereid clusters and their association with leaf traces suggests they may be stabilizing the corm-leaf connection to protect vascular tissues from physical damage. The proposed X-ray microCT technique is an excellent tool for determination of the 3D structure of E. vaginatum corms and may be used to detect alterations in tissue structure and chemistry in response to environmental change in this and other Cyperaceous species.

  15. OSTEOSYNTHESIS OF PROXIMAL HUMERAL END FRACTURES WITH FIXED-ANGLE PLATE AND LOCKING SCREWS: TECHNIQUE AND RESULTS

    Science.gov (United States)

    Cohen, Marcio; Amaral, Marcus Vinicius; Monteiro, Martim; Brandão, Bruno Lobo; Motta Filho, Geraldo Rocha

    2015-01-01

    Describe the results of proximal humeral fractures surgically treated with the Philos locking plate system. Method: Between March 2003 and October 2004 we prospectively reviewed 24 of 26 patients with proximal humerus fractures treated with a Philos plate. The mean follow-up time was 12 months and the mean age of patients was 57 years. Six patients had four-part proximal humerus fractures, 11 patients had three-part proximal humerus fractures, and nine patients had two-part proximal humerus fractures. Clinical evaluation was performed using the University of California at Los Angeles (UCLA) criteria. Results: The mean UCLA score was 30 points (17-34). All fractures showed union. Three patients showed fracture union at varus position. The mean UCLA score for these patients was 27 points. Conclusion: Osteosynthesis with Philos plate provides a stable fixation method with good functional outcome. PMID:26998460

  16. Surgical and pathomorphological results of total mesorectumectomy by using waterjet dissection technique in patients with rectal cancer

    Directory of Open Access Journals (Sweden)

    D. V. Sidorov

    2016-01-01

    Full Text Available Background. The paper presents our own experience of using a waterjet dissector ERBEJET2® in the course of surgical interventions for colorectal cancer. This experience is unique for Russia.Materials and methods. Waterjet dissection method associated with total  mesorectumectomy was used by us in 20 patients suffering from rectal cancer. An average age of patients was 59.2 ± 13.9 years. In all the patients surgeries were performed for adenogenic colorectal cancer, morphologically verified at the preoperative stage. Resected preparations were studied on morphological level. For comparison, two control groups of 20 patients were selected, in which the rectum mobilization was performed by using monopolar coagulator and harmonic scalpel. The studied groups were matched by gender, age, location and the tumor extent. All the surgeries were performed by one surgical team.Results. Results of the study demonstrated advantages of waterjet dissection when performing total mesorectumectomy due to a minimum depth of tissue damage on the lateral margin of resection.Conclusion. Waterjet dissectors have taken their place in the extensive list of tools used when performing surgical interventions for colorectal cancer, that allows to expect an improvement of functional and oncological results of the surgical treatment.

  17. Long-term results of Troidl's technique of endoscopic pneumatic dilatation for achalasia of the esophagus. A prospective clinical trial.

    Science.gov (United States)

    Eypasch, E; Troidl, H; Sommer, H; Vestweber, K H

    1987-01-01

    In a prospective clinical trial, 26 consecutive patients underwent endoscopic pneumatic dilatation over a 10-year period. Dilatation was achieved by means of a balloon attached to a normal gastrointestinal fiberscope. With the endoscope in an inverse position, the device was placed in the cardia and the dilatation process was monitored macroscopically. Before dilatation, patients suffered from dysphagia (92%), reduced speed of swallowing (100%), symptom aggravation under stress (73%), weight loss (50%), aspiration, pain, regurgitation, and vomiting. After dilatation and long-term follow-up (mean of 5 years), symptoms could be markedly reduced, especially the speed of eating and symptom aggravation under stress. Excellent and good results (Visick scale) were achieved in 76%. Fair results were achieved in 20%. To date, perforation and other complications have not occurred. Mortality was zero. Our series was an uncontrolled trial, so the results are hardly comparable to other studies. Furthermore, the small number of patients in our study represents a weak point with regard to complications. We conclude that the main advantages of the procedure are its simplicity and practicability. The simple procedure may be the method of choice in elderly patients. Of course, no final decision can be made until a well-designed controlled trial has been carried out.

  18. A comparative study of Sephadex, glass wool and Percoll separation techniques on sperm quality and IVF results for cryopreserved bovine semen

    Science.gov (United States)

    Lee, Hae-Lee; Kim, Sue-Hee; Ji, Dong-Beom

    2009-01-01

    The aim of this study was to compare the effects of spermatozoa separation techniques on sperm quality and in-vitro fertilization (IVF) results for cryopreserved bovine semen. Sephadex, glass wool and Percoll gradient separation techniques were used for sperm separation and sperm motility, morphology and membrane integrity were evaluated before and after separation. Also, cleavage and blastocyst developmental rate were investigated after IVF with sperm recovered by each separation technique. The motility of samples obtained by the three separation techniques were greater compared to the control samples (p < 0.05). The percentage of spermatozoa with intact plasma-membrane integrity, identified by 6-carboxyfluoresceindiacetate/propidium iodide fluorescent staining and the hypo-osmotic swelling test, was highest in the glass wool filtration samples (p < 0.05). The cleavage and blastocyst rate of total oocytes produced from glass wool filtration samples were also higher than the control and Sephadex filtration samples (p < 0.05), but were not significantly different from Percoll separation samples. However, a significantly greater number of cleaved embryos produced by glass wool filtration developed to blastocyst stage than those produced by Percoll separation (p < 0.05). These results indicate that spermatozoa with good quality can be achieved by these three separation techniques and can be used for bovine IVF. In particular, it suggests that glass wool filtration would be the most effective method of the three for improving sperm quality and embryo production for cryopreserved bovine spermatozoa. PMID:19687626

  19. Pulsed carbon dioxide laser for cartilage vaporization and subchondral bone perforation in horses. Part I: Technique and clinical results.

    Science.gov (United States)

    Roth, J E; Nixon, A J; Gantz, V A; Meyer, D; Mohammed, H

    1991-01-01

    A carbon dioxide laser, used in a rapidly pulsed mode, was evaluated for intra-articular use in horses. Under arthroscopic guidance, a lensed 5 mm laser probe attached directly to a hand-held carbon dioxide laser was inserted into one intercarpal joint of eight horses. In four horses, a cartilage crater 1 cm in diameter was created to the level of the subchondral bone of the articular surface of the third carpal bone. In four horses, the laser was directed perpendicular to the articular surface of the third carpal bone and activated to penetrate the cartilage and subchondral bone. The intercarpal joint of the opposite carpus in each horse was subjected to arthroscopic examination and insertion of the laser probe for an equivalent time. The laser was not activated and these joints served as sham operated controls. The horses were evaluated clinically for 8 weeks, then euthanatized, and the joints were examined radiographically, grossly, and histologically. Pulsed carbon dioxide laser vaporized cartilage readily but penetrated bone poorly. Cartilage vaporization resulted in no greater swelling, heat, pain on flexion, lameness, or synovial fluid reaction than the sham procedure. Laser drilling resulted in a shallow, charred hole with a tenacious carbon residue, and in combination with the thermal damage to deeper bone, resulted in increased swelling, mild lameness and a low-grade, but persistent synovitis. The carbon dioxide laser is a useful intra-articular instrument for removal of cartilage and has potential application in inaccessible regions of diarthrodial joints. It does not penetrate bone sufficiently to have application in subchondral drilling.

  20. Pet Food Palatability Evaluation: A Review of Standard Assay Techniques and Interpretation of Results with a Primary Focus on Limitations.

    Science.gov (United States)

    Aldrich, Gregory C; Koppel, Kadri

    2015-01-16

    The pet food industry continues to grow steadily as a result of new innovative products. Quality control and product development tests for pet foods are typically conducted through palatability testing with dogs and cats. Palatability is the measure of intake of a food that indicates acceptance or the measure of preference of one food over another. Pet food palatability is most commonly measured using a single-bowl or a two-bowl assay. While these tests answer some questions about the animals' perception of the food, there are many limitations as well. This review addresses some of these limitations and indicates opportunities for future research.

  1. Early results from an angiosome-directed open surgical technique for venous arterialization in patients with critical lower limb ischemia

    DEFF Research Database (Denmark)

    Houlind, Kim Christian; Hallenberg, Christian; Christensen, Johnny

    2013-01-01

    Background: Patients with critical lower limb ischemia without patent pedal arteries cannot be treated by the conventional arterial reconstruction. Venous arterialization has been suggested to improve limb salvage in this subgroup of patients but has not gained wide acceptance. We report our early...... experience after implementing deep and superficial venous arterialization of the lower limb. Materials and methods: Ten patients with critical ischemia and without crural or pedal arteries available for conventional bypass surgery or angioplasty were treated with distal venous arterialization. Inflow...... of the ischemic lesion. Venous valves were destroyed using antegrade valvulotomes, guide wires, knob needles, or retrograde valvulotomes via an extra incision. Results: Seven of the operated limbs were amputated after 23 (1256) days (median [range]). The main reasons for amputation were lack of healing of either...

  2. Validation Techniques of network harmonic models based on switching of a series linear component and measuring resultant harmonic increments

    DEFF Research Database (Denmark)

    Wiechowski, Wojciech Tomasz; Lykkegaard, Jan; Bak, Claus Leth

    2007-01-01

    In this paper two methods of validation of transmission network harmonic models are introduced. The methods were developed as a result of the work presented in [1]. The first method allows calculating the transfer harmonic impedance between two nodes of a network. Switching a linear, series network...... are used for calculation of the transfer harmonic impedance between the nodes. The determined transfer harmonic impedance can be used to validate a computer model of the network. The second method is an extension of the fist one. It allows switching a series element that contains a shunt branch......, as for example a transmission line. Both methods require that harmonic measurements performed at two ends of the disconnected element are precisely synchronized....

  3. New digital demodulator with matched filters and curve segmentation techniques for BFSK demodulation: FPGA implementation and results

    Directory of Open Access Journals (Sweden)

    Jorge Torres Gómez

    2016-04-01

    Full Text Available The current article addresses digital implementation of new demodulation schemes for Binary Frequency Shift Keying (BFSK, and has two main objectives: of the description of the performance of the new processing method and its implementation on FPGA technology. Performance is analyzed by means of the total number of demodulated bits free of errors without noise, and by means of the BER parameter. The proposed method exhibits to have better performance than the solutions reported. Additionally, the solution obtained shows lower complexity than reported methods in regard to the total number of adders and multipliers. The implementation is described for FPGA systems, and the System Generator software is used for testing and simulating the results.

  4. Evaluation of the functional results after different techniques for treatment of retinal detachment due to macular holes.

    Science.gov (United States)

    Rashed, O; Sheta, S

    1989-01-01

    A total of 50 eyes with retinal detachment due to macular holes were treated in the period from July 1986 to December 1987. In all, 10 eyes underwent pneumatic retinopexy using plain room air. A total of 30 eyes were treated by pars plana vitrectomy, followed by fluid/air exchange, with no treatment of the macular break; in 9 of these the detachment recurred, reflattening of the retina by air tamponade followed by laser photo-coagulation. The other 10 eyes underwent pars plana vitrectomy followed by silicone oil tamponading because of proliferative vitreoretinopathy (PVR). This paper compares the functional results for each group. The parameters used included visual acuity, color vision and visual fields.

  5. Radial forearm flap plus Flexor Carpi Radialis tendon in Achilles tendon reconstruction: Surgical technique, functional results, and gait analysis.

    Science.gov (United States)

    Innocenti, Marco; Tani, Massimiliano; Carulli, Christian; Ghezzi, Serena; Raspanti, Andrea; Menichini, Giulio

    2015-11-01

    Wound dehiscence, infection, and necrosis of tendon and overlying skin are severe complications after open repairs of Achilles tendon. A simultaneous reconstruction should be provided in a single stage operation. We evaluated the outcomes of one of the possible options: the radial forearm free flap with Flexor Carpi Radialis (FCR) tendon. Between 2006 and 2014, six patients affected by infection and necrosis after Achilles tendon open repair underwent multi-tissutal reconstruction by a composite radial forearm free flap including a vascularized FCR tendon. The mean skin and tendon defect was respectively 9.8 cm × 4.7 cm and 6.5 cm. After reconstruction, patients underwent clinical examination, including the Achilles Tendon Total Rupture Score (ATRS) questionnaire, DASH score, MRI study, and a computer-assisted gait analysis. All flaps survived and no complications were recorded. Full weightbearing was allowed within 2 months after surgery. The mean follow-up was 36.2 months (range 12-96). MRI showed an optimal reconstruction of the tendon. Range of motion was minimally reduced if compared to the contralateral side. Gait analysis showed the recovery of a nearly symmetrical stance phase, time to heel off, and step length of the gate. ATRS and DASH score improved to a mean value of 85.2 (range 83-88) and 8.0 (range 3-15) respectively. This procedure provided an anatomical reconstruction of the Achilles tendon and skin achieving good and objective functional results; donor site morbidity was limited to the sacrifice of the radial artery, which, in our opinion, is a minor drawback if compared to the quality of the results. © 2015 Wiley Periodicals, Inc.

  6. Results of applying a non-evaporative mitigation technique to laser-initiated surface damage on fused-silica

    Energy Technology Data Exchange (ETDEWEB)

    Adams, J J; Bolourchi, M; Bude, J D; Guss, G M; Matthews, M J; Nostrand, M C

    2010-10-26

    We present results from a study to determine an acceptable CO{sub 2} laser-based non-evaporative mitigation protocol for use on surface damage sites in fused-silica optics. A promising protocol is identified and evaluated on a set of surface damage sites created under ICF-type laser conditions. Mitigation protocol acceptability criteria for damage re-initiation and growth, downstream intensification, and residual stress are discussed. In previous work, we found that a power ramp at the end of the protocol effectively minimizes the residual stress (<25 MPa) left in the substrate. However, the biggest difficulty in determining an acceptable protocol was balancing between low re-initiation and problematic downstream intensification. Typical growing surface damage sites mitigated with a candidate CO{sub 2} laser-based mitigation protocol all survived 351 nm, 5 ns damage testing to fluences >12.5 J/cm{sup 2}. The downstream intensification arising from the mitigated sites is evaluated, and all but one of the sites has 100% passing downstream damage expectation values. We demonstrate, for the first time, a successful non-evaporative 10.6 {micro}m CO{sub 2} laser mitigation protocol applicable to fused-silica optics used on fusion-class lasers like the National Ignition Facility (NIF).

  7. Techniques, tools and best practices for ligand electron-density analysis and results from their application to deposited crystal structures.

    Science.gov (United States)

    Pozharski, Edwin; Weichenberger, Christian X; Rupp, Bernhard

    2013-02-01

    As a result of substantial instrumental automation and the continuing improvement of software, crystallographic studies of biomolecules are conducted by non-experts in increasing numbers. While improved validation almost ensures that major mistakes in the protein part of structure models are exceedingly rare, in ligand-protein complex structures, which in general are most interesting to the scientist, ambiguous ligand electron density is often difficult to interpret and the modelled ligands are generally more difficult to properly validate. Here, (i) the primary technical reasons and potential human factors leading to problems in ligand structure models are presented; (ii) the most common categories of building errors or overinterpretation are classified; (iii) a few instructive and specific examples are discussed in detail, including an electron-density-based analysis of ligand structures that do not contain any ligands; (iv) means of avoiding such mistakes are suggested and the implications for database validity are discussed and (v) a user-friendly software tool that allows non-expert users to conveniently inspect ligand density is provided.

  8. A novel field transplantation technique reveals intra-specific metal-induced oxidative responses in strains of Ectocarpus siliculosus with different pollution histories.

    Science.gov (United States)

    Sáez, Claudio A; González, Alberto; Contreras, Rodrigo A; Moody, A John; Moenne, Alejandra; Brown, Murray T

    2015-04-01

    A novel field transplantation technique, in which seaweed material is incorporated into dialysis tubing, was used to investigate intra-specific responses to metals in the model brown alga Ectocarpus siliculosus. Metal accumulation in the two strains was similar, with higher concentrations in material deployed to the metal-contaminated site (Ventanas, Chile) than the pristine site (Quintay, Chile). However, the oxidative responses differed. At Ventanas, strain Es147 (from low-polluted site) underwent oxidative damage whereas Es524 (from highly polluted site) was not affected. Concentrations of reduced ascorbate (ASC) and reduced glutathione (GSH) were significantly higher in Es524. Activities of the antioxidant enzymes superoxide dismutase (SOD), ascorbate peroxidase (APX), catalase (CAT), and glutathione reductase (GR) all increased in Es524, whereas only SOD increased in Es147. For the first time, employing a field transplantation technique, we provide unambiguous evidence of inter-population variation of metal-tolerance in brown algae and establish that antioxidant defences are, in part, responsible.

  9. Bayesian Machine Learning Techniques for revealing complex interactions among genetic and clinical factors in association with extra-intestinal Manifestations in IBD patients

    Science.gov (United States)

    Menti, E; Lanera, C; Lorenzoni, G; Giachino, Daniela F.; Marchi, Mario De; Gregori, Dario; Berchialla, Paola

    2016-01-01

    The objective of the study is to assess the predictive performance of three different techniques as classifiers for extra-intestinal manifestations in 152 patients with Crohn’s disease. Naïve Bayes, Bayesian Additive Regression Trees and Bayesian Networks implemented using a Greedy Thick Thinning algorithm for learning dependencies among variables and EM algorithm for learning conditional probabilities associated to each variable are taken into account. Three sets of variables were considered: (i) disease characteristics: presentation, behavior and location (ii) risk factors: age, gender, smoke and familiarity and (iii) genetic polymorphisms of the NOD2, CD14, TNFA, IL12B, and IL1RN genes, whose involvement in Crohn’s disease is known or suspected. Extra-intestinal manifestations occurred in 75 patients. Bayesian Networks achieved accuracy of 82% when considering only clinical factors and 89% when considering also genetic information, outperforming the other techniques. CD14 has a small predicting capability. Adding TNFA, IL12B to the 3020insC NOD2 variant improved the accuracy.

  10. Surface Deformation Associated with Geothermal Fluids Extraction at the Cerro Prieto Geothermal Field, Baja California, Mexico Revealed by DInSAR Technique

    Science.gov (United States)

    Sarychikhina, O.; Glowacka, E.; Mojarro, J.

    2016-08-01

    The Differential Synthetic Aperture Radar Interferometry (DInSAR) is widely used for surface deformation detection and monitoring.In this paper, ERS-1/2, ENVISAT and RADARSAT-2 synthetic aperture radar (SAR) images acquired between 1993 and 2014 were processed to investigate the evolution of surface deformation at the Cerro Prieto geothermal field, Baja California, Mexico. The conventional DInSAR together with the interferogram stacking method was applied. Average LOS (line of sight) displacement velocity maps were generated for different periods: 1993 - 1997, 1998 - 2000, 2004, 2005, 2007, 2009, and 2012 - 2014, revealing that the area corresponding to Cerro Prieto basin presented the important surface deformation (mainly subsidence) during the entire time of investigation. The changes in the surface deformation pattern and rate were identified. These changes have a good correlation in time with the changes of production in the Cerro Prieto geothermal field.

  11. Initial Results from a New Lake Elsinore Sediment Core Reveal Evidence for Hydrologic Change During the Late-Glacial/Holocene Transition

    Science.gov (United States)

    Fantozzi, J. M.; Kirby, M. E.; Lund, S.; Hiner, C.

    2010-12-01

    While there are several well-developed records of marine climate from Southern California that span the late-Glacial/Holocene transition, there are currently no high-resolution terrestrial counterparts. In June 2010, a 20 meter sediment core covering 10-30 meters below the sediment-water interface was extracted from the depocenter of Lake Elsinore, California - the largest natural, permanent lake in the region. Here, we present the initial results of a multi-proxy study on the section of this sediment core that spans the late-Glacial/Holocene transition (10-18.5 m below the sediment-water line [bswl]). Initial results reveal three distinct sediment units. Unit I (10-15m bswl) is composed of a homogeneous, often mottled (bioturbated?), gray mud with high and moderately variable magnetic susceptibility values (avg=1.20±0.29x10-7m3/kg), low organic matter content (6.50±0.83%), and highly variable carbonate content (12.21±4.89%). Unit II (15-17m bswl) is a transitional unit that begins as a gray mud similar to that of Unit I and transitions into a massive to laminated brown mud with low and variable magnetic susceptibility values (0.88±0.38x10-7m3/kg), increasing organic matter content (11.52±2.19%), and highly variable carbonate content (10.84±4.75%). Unit III (17-18.5m bswl) is characterized by a massive to laminated brown mud with very low and stable magnetic susceptibility values (0.87±0.19x10-7m3/kg), declining organic matter content (11.21±2.02%), and low to negligible carbonate content (5.0±0.87%). Together, these data indicate a significant change in Lake Elsinore’s depositional environment that is likely related to hydrologic change (i.e. average lake level) during the late Glacial to Holocene transition - a change that has not previously been documented in Southern California.

  12. Passage Retrieval: A Probabilistic Technique.

    Science.gov (United States)

    Melucci, Massimo

    1998-01-01

    Presents a probabilistic technique to retrieve passages from texts having a large size or heterogeneous semantic content. Results of experiments comparing the probabilistic technique to one based on a text segmentation algorithm revealed that the passage size affects passage retrieval performance; text organization and query generality may have an…

  13. A novel technique using potassium permanganate and reflectance confocal microscopy to image biofilm extracellular polymeric matrix reveals non-eDNA networks in Pseudomonas aeruginosa biofilms.

    Science.gov (United States)

    Swearingen, Matthew C; Mehta, Ajeet; Mehta, Amar; Nistico, Laura; Hill, Preston J; Falzarano, Anthony R; Wozniak, Daniel J; Hall-Stoodley, Luanne; Stoodley, Paul

    2016-02-01

    Biofilms are etiologically important in the development of chronic medical and dental infections. The biofilm extracellular polymeric substance (EPS) determines biofilm structure and allows bacteria in biofilms to adapt to changes in mechanical loads such as fluid shear. However, EPS components are difficult to visualize microscopically because of their low density and molecular complexity. Here, we tested potassium permanganate, KMnO4, for use as a non-specific EPS contrast-enhancing stain using confocal laser scanning microscopy in reflectance mode. We demonstrate that KMnO4 reacted with EPS components of various strains of Pseudomonas, Staphylococcus and Streptococcus, yielding brown MnO2 precipitate deposition on the EPS, which was quantifiable using data from the laser reflection detector. Furthermore, the MnO2 signal could be quantified in combination with fluorescent nucleic acid staining. COMSTAT image analysis indicated that KMnO4 staining increased the estimated biovolume over that determined by nucleic acid staining alone for all strains tested, and revealed non-eDNA EPS networks in Pseudomonas aeruginosa biofilm. In vitro and in vivo testing indicated that KMnO4 reacted with poly-N-acetylglucosamine and Pseudomonas Pel polysaccharide, but did not react strongly with DNA or alginate. KMnO4 staining may have application as a research tool and for diagnostic potential for biofilms in clinical samples.

  14. Relations between Anthropometric Characteristics and Motor Abilities of 14 – 15U Female Swimmers on 50m Result for each Technique

    Directory of Open Access Journals (Sweden)

    Goran Dimitrić

    2016-10-01

    Full Text Available In aim of correlation between antropometric characteristics, motor abilities and results of swimming 50m in all swimming techniques, a group of 22 swimmers (girls of Serbian national team, aged 14-15, underwent some anthropometric measurements as well as some motor abilities. Observed longitudinal dimensions were: body height, body mass, arm span and torax circumference and observed motor abilities were: body strength (arms, legs, stomach and flexibility (trunk and arms. Regression analisys showed that arm span corellated with 50m butterfly and free style score as well as strenght of body and legs corellated with 50m backstroke and free style score. Other measures didn΄t corelatted significantly on this sample. Study results confirms importance of arm span and some segments of body strenhgt of swimmers (girls for successful swimm on 50m in butterfly, backstroke and freestyle techniques in the age 14-15 years.

  15. Evaluation of the results from surgical treatment of fractures of the lateral extremity of the clavicle, using the double ligature technique

    Directory of Open Access Journals (Sweden)

    Alberto Naoki Miyazaki

    2015-04-01

    Full Text Available OBJECTIVE: To evaluate the incidence of consolidation in surgical treatment of fractures of the lateral extremity of the clavicle using the double subcoracoid ligature technique, with nonabsorbable No. 5 thread.METHODS: Between May 1993 and June 2013, the Shoulder and Elbow Group of our service surgically treated 116 patients (116 shoulders with fractures of the lateral extremity of the clavicle. Among these, we were able to reassess 65 cases. The surgical technique used consisted of double subcoracoid ligature with two nonabsorbable threads. In two patients classified as type III, we had to combine this technique with use of an interfragmentary screw for fixation of the intra-articular portion of the acromioclavicular joint.RESULTS: We achieved fracture consolidation in 90%. Fourteen cases (21% evolved with major complications: four cases of pseudarthrosis, five of adhesive capsulitis, two of delayed consolidation and three of loss of reduction. Two cases (3% evolved with minor complications of skin granuloma.CONCLUSION: The double ligature technique for fractures of the lateral extremity of the clavicle promotes the stabilization needed for consolidation to take place, without the need for synthesis using metal components. It avoids reoperation for the synthesis material to be removed. Moreover, it is a low-cost procedure with good reproducibility and preservation of the acromioclavicular joint.

  16. Characteristics of intercommunications of sport results and indexes of technique and tactic of competition activity of highly qualified sportsmen of karate-do.

    Directory of Open Access Journals (Sweden)

    Baranov M.V.

    2011-02-01

    Full Text Available The effectiveness of the individualization of technical and tactical training of athletes of karate-offensive, maneuver, and expectant management style duels. By analyzing the competitive activities of representatives of these styles, world and European champion 2007-2009 classification features were identified techniques and tactics of karate-do and established differences in their use of technical-tactical vehicles. Results of correlation analysis of the relationship of sports results and performance of technical and tactical actions of these athletes can determine the direction of individualization of training in different styles of karate fights.

  17. IS THERE A METALLICITY CEILING TO FORM CARBON STARS?-A NOVEL TECHNIQUE REVEALS A SCARCITY OF C STARS IN THE INNER M31 DISK

    Energy Technology Data Exchange (ETDEWEB)

    Boyer, M. L. [Observational Cosmology Lab, Code 665, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Girardi, L. [Osservatorio Astronomico di Padova-INAF, Vicolo dell' Osservatorio 5, I-35122 Padova (Italy); Marigo, P. [Department of Physics and Astronomy G. Galilei, University of Padova, Vicolo dell' Osservatorio 3, I-35122 Padova (Italy); Williams, B. F.; Rosenfield, P.; Dalcanton, J. J.; Weisz, D. R. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Aringer, B.; Nowotny, W. [Department of Astrophysics, University of Vienna, Tuerkenschanzstrasse 17, A-1180 Wien (Austria); Dorman, C. E.; Guhathakurta, P. [University of California Observatories/Lick Observatory, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States); Melbourne, J. L. [Caltech Optical Observatories, Division of Physics, Mathematics and Astronomy, Mail Stop 301-17, California Institute of Technology, Pasadena, CA 91125 (United States); Olsen, K. A. G., E-mail: martha.boyer@nasa.gov [National Optical Astronomy Observatory, 950 North Cherry Avenue, Tucson, AZ 85719 (United States)

    2013-09-01

    We use medium-band near-infrared (NIR) Hubble Space Telescope WFC3 photometry with model NIR spectra of asymptotic giant branch (AGB) stars to develop a new tool for efficiently distinguishing carbon-rich (C-type) AGB stars from oxygen-rich (M-type) AGB stars in galaxies at the edge of and outside the Local Group. We present the results of a test of this method on a region of the inner disk of M31, where we find a surprising lack of C stars, contrary to the findings of previous C star searches in other regions of M31. We find only one candidate C star (plus up to six additional, less certain C star candidates), resulting in an extremely low ratio of C to M stars (C/M= (3.3{sup +20}{sub -0.1}) Multiplication-Sign 10{sup -4}) that is one to two orders of magnitude lower than other C/M estimates in M31. The low C/M ratio is likely due to the high metallicity in this region which impedes stars from achieving C/O > 1 in their atmospheres. These observations provide stringent constraints to evolutionary models of metal-rich AGB stars and suggest that there is a metallicity threshold above which M stars are unable to make the transition to C stars, dramatically affecting AGB mass loss and dust production and, consequently, the observed global properties of metal-rich galaxies.

  18. Is there a metallicity ceiling to form carbon stars? - A novel technique reveals a scarcity of C stars in the inner M31 disk

    CERN Document Server

    Boyer, M L; Marigo, P; Williams, B F; Aringer, B; Nowotny, W; Rosenfield, P; Dorman, C E; Guhathakurta, P; Dalcanton, J J; Melbourne, J L; Olsen, K A G; Weisz, D R

    2013-01-01

    We use medium-band near-infrared (NIR) Hubble Space Telescope WFC3 photometry with model NIR spectra of Asymptotic Giant Branch (AGB) stars to develop a new tool for efficiently distinguishing carbon-rich (C-type) AGB stars from oxygen-rich (M-type) AGB stars in galaxies at the edge of and outside the Local Group. We present the results of a test of this method on a region of the inner disk of M31, where we find a surprising lack of C stars, contrary to the findings of previous C star searches in other regions of M31. We find only 1 candidate C star (plus up to 6 additional, less certain C stars candidates), resulting in an extremely low ratio of C to M stars (C/M = (3.3(+20,-0.1))x10^-4) that is 1-2 orders of magnitude lower than other C/M estimates in M31. The low C/M ratio is likely due to the high metallicity in this region which impedes stars from achieving C/O > 1 in their atmospheres. These observations provide stringent constraints evolutionary models of metal-rich AGB stars and suggest that there is ...

  19. Is There a Metallicity Ceiling to Form Carbon Stars? - A Novel Technique Reveals a Scarcity of C-Stars in the Inner M31 Disk

    Science.gov (United States)

    Boyer, Martha L.; Girardi, L.; Marigo, P.; Williams, B. F.; Aringer, B.; Nowotny, W.; Rosenfield, P.; Dorman, C. E.; Guhathakurta, P.; Dalcanton, J. J.; Melbourne, J. L.; Olsen, K. A. G.; Weisz, D. R.

    2013-01-01

    We use medium-band near-infrared (NIR) Hubble Space Telescope WFC3 photometry with model NIR spectra of Asymptotic Giant Branch (AGB) stars to develop a new tool for efficiently distinguish- ing carbon-rich (C-type) AGB stars from oxygen-rich (M-type) AGB stars in galaxies at the edge of and outside the Local Group. We present the results of a test of this method on a region of the inner disk of M31, where we nd a surprising lack of C stars, contrary to the ndings of previous C star searches in other regions of M31. We nd only 1 candidate C star (plus up to 6 additional, less certain C stars candidates), resulting in an extremely low ratio of C to M stars (C=M = (3.3(sup +20)(sub - 0.1) x 10(sup -4)) that is 1-2 orders of magnitude lower than other C/M estimates in M31. The low C/M ratio is likely due to the high metallicity in this region which impedes stars from achieving C/O > 1 in their atmospheres. These observations provide stringent constraints to evolutionary models of metal-rich AGB stars and suggest that there is a metallicity threshold above which M stars are unable to make the transition to C stars, dramatically affecting AGB mass loss and dust production and, consequently, the observed global properties of metal-rich galaxies.

  20. Long-Term Results of Mini-Open Repair Technique in the Treatment of Acute Achilles Tendon Rupture: A Prospective Study.

    Science.gov (United States)

    Taşatan, Ersin; Emre, Tuluhan Yunus; Demircioğlu, Demet Tekdöş; Demiralp, Bahtiyar; Kırdemir, Vecihi

    2016-01-01

    An ideal surgical treatment of acute Achilles tendon rupture includes restoring the original length of the tendon, minimizing possible adhesions with the surrounding tissues, minimizing the risk of repeat rupture, alleviating wound problems, and providing an acceptable cosmetic outcome. In the mini-open repair technique, unlike the percutaneous repair technique, the quality of the tenodesis can be visualized without disturbing the healing potential of the surrounding tissues, thus minimizing wound problems. The purpose of the present study was to assess the long-term results of the mini-open repair technique in patients with acute Achilles tendon rupture. A total of 20 consecutive patients with acute Achilles tendon rupture, admitted to our inpatient clinic from October 2003 to March 2008, were included in the present study. The patients underwent Achilles tenodesis with the mini-open repair technique, and each patient was followed up for 5 years. The study was completed in April 2013. The surgical procedure was performed with the assistance of a device designed in our orthosis laboratories, similarly to that defined by Assal et al. Of the 20 patients, 18 were male and 2 were female. Their mean age was 39.3 (range 21 to 55) years. The Achilles tendon rupture was located on the left side in 15 patients (75%) and on the right side in 5 patients (25%). The mean follow-up duration was 58.5 (range 18 to 60) months and no complications occurred during the follow-up period, including repeat rupture, wound site infection, and sural nerve injury. The mean American Orthopaedic Foot and Ankle Society scale score for the patients was 99.2 (range 94 to 100) points at the final follow-up visit. All our patients were able to return to work and sporting activities. According to the Trillat scores, the outcome was excellent in 19 patients and good in 1 patient at the 18th postoperative month. No complaint, such as pain or loss of function, that might have a negative effect on the

  1. Discovering diamonds under coal piles: Revealing exclusive business intelligence about online consumers through the use of Web Data Mining techniques embedded in an analytical customer relationship management framework

    Directory of Open Access Journals (Sweden)

    Myriam Ertz

    2016-02-01

    Full Text Available Web Mining has gained prominence over the last decade. This rise is concomitant with the upsurge of pure players, the multiple challenges of data deluge, the trend toward automation and integration within organization, as well as a desire for hyper segmentation. Confronted, partly or totally, with these multiple issues, companies recourse increasingly to replicate the data mining toolbox on web data. Although much is known about the technical aspect of WM, little is known about the extent to which WM actually fits within a customer relationship management system, designed at attracting and retaining the maximum amount of customers. An exploratory study involving twelve senior professionals and scholars indicated that WM is well-suited to achieve most of the customer relationship management objective, with regards to the profiling of existing web customers. The results of this study suggest that the engineering of WM processes into analytic customer relationship management systems, may yield highly beneficial returns, provided that some guidelines are scrupulously followed.

  2. Body image perception, satisfaction and somatotype in male and female athletes and non-athletes: results using a novel morphing technique.

    Science.gov (United States)

    Stewart, Arthur D; Benson, Philip J; Michanikou, Evangelia G; Tsiota, Dimitra G; Narli, Margarita K

    2003-10-01

    Thirty-six adults (24 males, 12 females) were assessed for anthropometric somatotype and body image (perception and satisfaction) by a novel technique using quantitative distortion of a digital still image. Software produced random distortions in nine body regions. The participants manipulated interactive slider controls to adjust each body feature in turn, recreate their perceived image and indicate their desired image. There were no differences in perception between the sexes. However, the ideal-actual differences (i.e. satisfaction) indicated that males desired larger and females smaller features, respectively, in the chest and thighs (P Somatotype analysis indicated that the physique associated with minimal dissatisfaction was 2.0-5.0-3.0 for males and 3.0-2.5-3.0 for females. Cluster analysis, combining anthropometric and satisfaction data, revealed seven distinct subgroups distinguished by particular attributes of physical appearance. We conclude that the method is reliable and that body image includes sex-specific, anthropometric, perceptual and personality-related components.

  3. MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Zangos, Stephan [Johann Wolfgang Goethe-University, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt/Main (Germany); Johann Wolfgang Goethe-University, Institute for Diagnostic and Interventional Radiology, Frankfurt/Main (Germany); Eichler, Katrin; Engelmann, Kerstin; Ahmed, Mukhtiar; Dettmer, Sebastian; Herzog, Christopher; Pegios, Wasilios; Wetter, A.; Lehnert, Thomas; Mack, Martin G.; Vogl, Thomas J. [Johann Wolfgang Goethe-University, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt/Main (Germany)

    2005-01-01

    The purpose of this study was to examine the feasibility and safety of MR-guided biopsies with a transgluteal approach in patients with uncertain or suspicious prostate lesions. Twenty-five patients with uncertain or suspicious focal prostate lesions detected by high-field MR imaging of the prostate gland using endorectal coil imaging were biopsied with a transgluteal approach in a low-field MRI system (0.2 T, Concerto, Siemens). The procedures were guided using T1-weighted FLASH sequences. The prostate gland was biopsied repeatedly with a coaxial technique through a 15-gauge pencil tip with a 16-gauge biopsy handy (median 3.8 samples per patient). Complications and biopsy findings were documented retrospectively. Using T1-weighted sequences biopsy procedures were performed successfully with MR guidance in all cases without any side effects or complications. The median intervention time was 11.3 min. Pathological findings revealed ten cases of hyperplasia or atrophy, three cases of prostatitis, ten cases of carcinoma and two cases of normal tissue. The clinical follow-up showed that in two patients prostate cancer was missed at MR-guided biopsy. Transgluteal MR-guided biopsy of the prostate gland is a safe and promising approach for histological clarification of uncertain or suspicious lesions. (orig.)

  4. Técnica de "mini-nuc" de Blumenthal: resultados de 454 casos Mini-nuc Blumenthal technique: results of 454 cases

    Directory of Open Access Journals (Sweden)

    Mauro Waiswol

    2001-06-01

    Full Text Available Objetivo: Analisar retrospectivamente os resultados do tratamento cirúrgico de catarata pela técnica de "Mini-Nuc" de Blumenthal. Método: Foram, assim, submetidos à extração extracapsular de catarata pela referida técnica, realizada sempre pelo mesmo cirurgião (MW, 454 olhos de 284 pacientes (148 mulheres e 136 homens, em período de seis anos (fevereiro de 1994 a março de 2000. Resultados: Os resultados apontaram baixas taxas de complicações intra-operatórias (4,8%, sendo que a da ruptura da cápsula posterior ocorreu em 3,7% dos casos. Correção da acuidade visual igual ou maior que 20/40 foi obtida em 89,1% dos casos. Conclusão: A técnica mostrou-se, portanto, eficaz, com a vantagem de prescindir de instrumentação sofisticada e envolver baixos custos.Purpose: In this retrospective study the results of surgical management of cataract by the Mini-Nuc Blumenthal technique were analyzed. Methods: ECCE with Mini-Nuc Blumenthal technique was carried out always by the same surgeon (M.W. on 454 eyes of 284 patients (148 women and 136 men during a period of six years (from February 1994 to March 2000. Results: Low rates (4.8% of transoperative complications were recorded; posterior capsule rupture occurred in 3.7% of the cases. Visual acuity equal to or higher than 20/40 was observed in 89.1% of the cases. Conclusion: The technique was efficient for cataract surgery with the advantage of dispensing with sophisticated instrumentation and involving low costs.

  5. Single-Center Experience and 1-Year Follow-up Results of 'Sandwich Technique' in the Management of Common Iliac Artery Aneurysms During EVAR

    Energy Technology Data Exchange (ETDEWEB)

    Ricci, Carmelo; Ceccherini, Claudio, E-mail: claudiocec@hotmail.it; Cini, Marco; Vigni, Francesco; Leonini, Sara [Policlinico Santa Maria alle Scotte, Azienda Ospedaliera Universitaria Senese, Radiologia Interventistica (Italy); Tommasino, Giulio; Muzzi, Luigi; Tucci, Enrico; Benvenuti, Antonio; Neri, Eugenio [Policlinico Santa Maria alle Scotte, Azienda Ospedaliera Universitaria Senese, Chirurgia del Cuore e dei grossi vasi (Italy)

    2012-10-15

    Purpose: Abdominal aortic aneurysm (AAA) accompanied by common iliac artery (CIA) aneurysms requires a more demanding procedure owing to the difficulties in obtaining an adequate distal landing zone for the stent-graft limb(s), a potential site of endoleak. The 'sandwich technique' is a procedure to increase EVAR feasibility in the setting of adverse or challenging CIA anatomy. Its main advantages include no restrictions in terms of CIA diameter or length or internal iliac artery (IIA) diameter, no need to wait for a specific stent-graft. Our purpose is to describe our single-center experience and one year follow-up results of this new procedure. Materials and Methods: From April 2009 to June 2010, the sandwich technique was performed in our institution in 7 patients treated for AAA and unilateral CIA aneurysms (n. 5) or bilateral CIA aneurysms (n. 2). Inclusion criteria were the presence of unilateral or bilateral CIA aneurysm (independently from its diameter), IIA artery measuring up to 9 mm in its maximum diameter, not dilatation of IIA and EIA. Results: The mean follow-up length was 15 months (range: 14-20 months). All stent-implanted iliac branches remained patent on 1 year follow-up and IIA flow was preserved. None of the patients had symptoms of pelvic ischemia. CT scan follow-up showed aneurysm shrinkage in five patients, without any sign of endoleaks in all cases. Conclusions: In selected cases, the 'sandwich technique' showed good outcomes confirming to be a safe and easy to perform way to overcome anatomical constraints and expanding the limits of EVAR.

  6. Using super-resolution technique to elucidate the effects of imaging resolution on transport properties resulting from pore-scale modelling simulations

    Science.gov (United States)

    Karsanina, Marina; Gerke, Kirill; Khirevich, Siarhei; Sizonenko, Timofey; Korost, Dmitry

    2017-04-01

    Permeability is one of the fundamental properties of porous media and is required for large-scale Darcian fluid flow and mass transport models. Whilst permeability can be directly measured at a range of scales, there are increasing opportunities to evaluate permeability from pore-scale simulations. It is well known that single phase flow properties of digital rocks will depend on the resolution of the 3D pore image. Such studies are usually performed by coarsening X-ray microtomography scans. Recently we have proposed a novel approach to fuse multi-scale porous media images using stochastic reconstruction techniques based on directional correlation functions. Here we apply this slightly modified approach to create 3D pore images of different spatial resolution, i.e. stochastic super-resolution method. Contrary to coarsening techniques, this approach preserves porosity values and allows to incorporate fine scale data coming from such imaging techniques as SEM or FIB-SEM. We compute absolute permeability of the same porous media species under different resolutions using lattice-Boltzmann and finite difference methods to model Stokes flow in order to elucidate the effects of image resolution on resulting permeability values and compare stochastic super-resolution technique against conventional coarsening image processing technique. References: 1) Karsanina, M.V., Gerke, K.M., Skvortsova, E.B. and Mallants, D. (2015) Universal spatial correlation functions for describing and reconstructing soil microstructure. PLoS ONE 10(5), e0126515. 2) Gerke, K. M., & Karsanina, M. V. (2015). Improving stochastic reconstructions by weighting correlation functions in an objective function. EPL (Europhysics Letters),111(5), 56002. 3) Gerke, K. M., Karsanina, M. V., Vasilyev, R. V., & Mallants, D. (2014). Improving pattern reconstruction using directional correlation functions. EPL (Europhysics Letters), 106(6), 66002. 4) Gerke, K.M., Karsanina, M. V, Mallants, D., 2015. Universal

  7. Revealing Interactions between Human Resources, Quality of Life and Environmental Changes within Socially-oriented Observations : Results from the IPY PPS Arctic Project in the Russian North

    Science.gov (United States)

    Vlasova, Tatiana

    2010-05-01

    Socially-oriented Observations (SOO) in the Russian North have been carried out within multidisciplinary IPY PPS Arctic project under the leadership of Norway and supported by the Research Council of Norway as well as Russian Academy of Sciences. The main objective of SOO is to increase knowledge and observation of changes in quality of life conditions (state of natural environment including climate and biota, safe drinking water and foods, well-being, employment, social relations, access to health care and high quality education, etc.) and - to reveal trends in human capital and capacities (health, demography, education, creativity, spiritual-cultural characteristics and diversity, participation in decision making, etc.). SOO have been carried out in industrial cities as well as sparsely populated rural and nature protection areas in observation sites situated in different bioms (from coastal tundra to southern taiga zone) of Murmansk, Arkhangelsk Oblast and Republic of Komi. SOO were conducted according to the international protocol included in PPS Arctic Manual. SOO approaches based both on local people's perceptions and statistics help to identify main issues and targets for life quality, human capital and environment improvement and thus to distinguish leading SOO indicators for further monitoring. SOO have revealed close interaction between human resources, quality of life and environmental changes. Negative changes in human capital (depopulation, increasing unemployment, aging, declining physical and mental health, quality of education, loss of traditional knowledge, marginalization etc.), despite peoples' high creativity and optimism are becoming the major driving force effecting both the quality of life and the state of environment and overall sustainability. Human induced disturbances such as uncontrolled forests cuttings and poaching are increasing. Observed rapid changes in climate and biota (ice and permafrost melting, tundra shrubs getting taller and

  8. New emerging results on molecular gas, stars, and dust at z~2, as revealed by low star formation rate and low stellar mass star-forming galaxies

    Science.gov (United States)

    Dessauges-Zavadsky, Miroslava; Schaerer, Daniel; Combes, Francoise; Egami, Eiichi; Swinbank, Mark; Richard, Johan; Sklias, Panos; Rawle, Tim D.

    2015-08-01

    The large surveys of main sequence star-forming galaxies (SFGs) at z~2, made at near-IR and mm wavelengths, have revolutionized our picture of galaxies at this critical epoch, where the cosmic star formation rate (SFR) density is at its peak and the stellar mass (Ms) assembly is rapid. They reveal that ~70% of SFGs are young, rotation dominated disk-like systems, yet dynamically hotter and geometrically thicker than local spirals, with larger molecular gas fractions (fgas).It is time to refine this modern picture of z~2 galaxies by extending the current studies toward the more numerous and typical SFGs, characterized by SFRstar, and dust properties in 8 such sub-SFR*, lensed SFGs at z=1.5-3.6, achieved thanks to gravitational lensing and IRAM/PdBI, Herschel, Spitzer, and HST multi-wavelength data. They extend the dynamical range in SFR and Ms of our compilation of CO-detected SFGs at z>1 from the literature, and allow us to revisit and propose new correlations between IR and CO luminosities, molecular gas, stellar and dust masses, specific SFR, molecular gas depletion timescales (tdepl), fgas, dust-to-gas ratios, and redshift, to be directly compared with galaxy evolution models.We find an increase of tdepl with Ms, as now revealed by low-Ms SFGs at z>1 and also observed at z=0, which contrasts with the acknowledged constant tdepl in "bathtub" models and refutes the linearity of the Kennicutt-Schmidt relation. A steady increase of fgas with redshift is predicted by cosmological models and is observed from z~0 to z~1.5, but is followed by a mild increase toward higher redshifts, which we further confirm with our highest redshift CO measurement in an SFR* galaxy at z=3.6. We provide the first fgas measure in z>1 SFGs at the low-Ms end 109.4

  9. Epidemiological Characteristics and Clinical Treatment Outcome of Typhoid Fever in Ningbo, China, 2005-2014: Pulsed-Field Gel Electorophoresis Results Revealing Great Proportion of Common Transmission Sources.

    Science.gov (United States)

    Song, Qifa; Yang, Yuanbin; Lin, Wenping; Yi, Bo; Xu, Guozhang

    2017-09-25

    We aimed to describe the molecular epidemiological characteristics and clinical treatment outcome of typhoid fever in Ningbo, China during 2005-2014. Eighty-eight Salmonella Typhi isolates were obtained from 307 hospitalized patients. Three prevalent pulsed-field gel electrophoresis (PFGE) patterns of 54 isolates from 3 outbreaks were identified. Overall, there were 64 (72.7%) isolates from clustered cases and 24 (27.3%) isolates from sporadic cases. Resistance to nalidixic acid (NAL) (n = 47; 53.4%) and ampicillin (AMP) (n = 40; 45.4%) and rare resistance to tetracycline (TET) (n = 2; 2.3%) and gentamicin (GEN) (n = 2; 2.3%) were observed. No isolates resistant to cefotaxime (CTX), chloramphenicol (CL), ciprofloxacin (CIP), and trimethoprim-sulfamethoxazole (SXT) were found. The occurrence of reduced sensitivity to CIP was 52.3% (n = 46). The medians of fever clearance time in cases with and without complications were 7 (interquartile range (IQR): 4-10) and 5 (IQR: 3-7) days (P = 0.001), respectively, when patients were treated with CIP or levofloxacin (LEV) and/or third-generation cephalosporins (CEP). Rates of serious complications were at low levels: peritonitis (2.3%), intestinal hemorrhage (6.8%), and intestinal perforation (1.1%). The present study revealed a long-term clustering trend with respect to PFGE patterns, occasional outbreaks, and the rapid spread of AMP resistance and decreased CIP susceptibility among S. Typhi isolates in recent years.

  10. Revealing pre-earthquake signatures in atmosphere and ionosphere associated with 2015 M7.8 and M7.3 events in Nepal. Preliminary results

    CERN Document Server

    Ouzounov, Dimitar; Davidenko, Dmitry

    2015-01-01

    We analyze retrospectively/prospectively the transient variations of three different physical parameters of atmosphere during the time of M7.8 and M7.3 events in Nepal: outgoing earth radiation (OLR), GPS/TEC and the thermodynamic proprieties in the lower atmosphere. We found that in mid March 2015 a rapid augment of satellite observed earth radiation in atmosphere and the anomaly located in close vicinity to the future M7.8 epicenter reached the maximum on April 21-22. Our continuous satellite analysis revealed prospectively the new strong anomaly on May 3th, which was the reason to contemplate another large event in the area. On May 12, 2015 a large aftershock of M7.3 occurred. The analysis of air temperature from weather ground station near Katmandu shows analogous patterns with offset 1-2 days earlier to the satellite anomalies. The GPS/TEC data analysis indicates an augment and variation in electron density reaching a maximum value during April 22-24 period. A strong negative TEC anomaly in the crest of ...

  11. The Atlas-3D project - IX. The merger origin of a fast and a slow rotating Early-Type Galaxy revealed with deep optical imaging: first results

    CERN Document Server

    Duc, Pierre-Alain; Serra, Paolo; Michel-Dansac, Leo; Ferriere, Etienne; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; McDermid, Richard M; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Weijmans, Anne-Marie; Young, Lisa M

    2011-01-01

    The mass assembly of galaxies leaves imprints in their outskirts, such as shells and tidal tails. The frequency and properties of such fine structures depend on the main acting mechanisms - secular evolution, minor or major mergers - and on the age of the last substantial accretion event. We use this to constrain the mass assembly history of two apparently relaxed nearby Early-Type Galaxies (ETGs) selected from the Atlas-3D sample, NGC 680 and NGC 5557. Our ultra deep optical images obtained with MegaCam on the Canada-France-Hawaii Telescope reach 29 mag/arcsec^2 in the g-band. They reveal very low-surface brightness (LSB) filamentary structures around these ellipticals. Among them, a gigantic 160 kpc long tail East of NGC 5557 hosts gas-rich star-forming objects. NGC 680 exhibits two major diffuse plumes apparently connected to extended HI tails, as well as a series of arcs and shells. Comparing the outer stellar and gaseous morphology of the two ellipticals with that predicted from models of colliding galax...

  12. Methods and Techniques Used to Convey Total System Performance Assessment Analyses and Results for Site Recommendation at Yucca Mountain, Nevada, USA

    Energy Technology Data Exchange (ETDEWEB)

    P. D. Mattie; J. A. McNeish; D. S. Sevougian; R. W. Andrews

    2001-04-13

    Total System Performance Assessment (TSPA) is used as a key decision-making tool for the potential geologic repository for high level radioactive waste at Yucca Mountain, Nevada, USA. Because of the complexity and uncertainty involved in a post-closure performance assessment, an important goal is to produce a transparent document describing the assumptions, the intermediate steps, the results, and the conclusions of the analyses. An important objective for a TSPA analysis is to illustrate confidence in performance projections of the potential repository given a complex system of interconnected process models, data, and abstractions. The methods and techniques used for the recent TSPA analyses demonstrate an effective process to portray complex models and results with transparency and credibility.

  13. Methods and Techniques Used to Convey Total System Performance Assessment Analyses and Results for Site Recommendation at Yucca Mountain, Nevada, USA

    Energy Technology Data Exchange (ETDEWEB)

    Mattie, Patrick D.; McNeish, Jerry A.; Sevougian, S. David [Duke Engineering and Services, Las Vegas, NV (United States); Andrews, Robert W. [Bechtel SAIC Company, Las Vegas, NV (United States)

    2001-07-01

    Total System Performance Assessment (TSPA) is used as a key decision-making tool for the potential geologic repository of high level radioactive waste at Yucca Mountain, Nevada USA. Because of the complexity and uncertainty involved in a post-closure performance assessment, an important goal is to produce a transparent document describing the assumptions, the intermediate steps, the results, and the conclusions of the analyses. An important objective for a TSPA analysis is to illustrate confidence in performance projections of the potential repository given a complex system of interconnected process models, data, and abstractions. The methods and techniques used for the recent TSPA analyses demonstrate an effective process to portray complex models and results with transparency and credibility.

  14. [Demands on professional nursing staff in institutions for dialysis from the view of male and female patients--the results of a survey by means of Critical Incident Technique].

    Science.gov (United States)

    Reuschenbach, Bernd; Mohr, Tina

    2005-04-01

    Contemporary models of competence in nursing are usually based on the questioning of nursing staff and therefore reflect their professional self-image. Our research focuses on the views of male and female patients on the relevant competencies of professional nursing staff. The "Critical Incident Techniqu" (CIT) (Flanagan, 1954) was applied to reveal relevant demands according to the patients' point of view. This technique has proven to be a suitable method for the reflection of nursing practice in this field of research and has provided realistic descriptions of staff behaviour. Nursing in the field of dialysis was chosen because of the specialized qualifications on staff needed and the high expectations assumed in this care. The CIT-interviews of one female and five male patients were transcribed and the content was analysed. Two main fields of demands were identified: "soft skills" and "hard skills". The patients especially stressed the demands on communicative and empathic competence ("soft skills"). Further research may be useful to validate the results with a larger sample.

  15. Improved L-C resonant decay technique for Q measurement of quasilinear power inductors: New results for MPP and ferrite powdered cores

    Science.gov (United States)

    Niedra, Janis M.; Gerber, Scott S.

    1995-01-01

    The L-C resonant decay technique for measuring circuit Q or losses is improved by eliminating the switch from the inductor-capacitor loop. A MOSFET switch is used instead to momentarily connect the resonant circuit to an existing voltage source, which itself is gated off during the decay transient. Very reproducible, low duty cycle data could be taken this way over a dynamic voltage range of at least 10:1. Circuit Q is computed from a polynomial fit to the sequence of the decaying voltage maxima. This method was applied to measure the losses at 60 kHz in inductors having loose powder cores of moly permalloy and an Mn-Zn power ferrite. After the copper and capacitor losses are separated out, the resulting specific core loss is shown to be roughly as expected for the MPP powder, but anomalously high for the ferrite powder. Possible causes are mentioned.

  16. Evaluation of result of minimally invasive plating osteosynthesis (MIPO technique in the treatment of fracture distal tibia: a prospective follow-up study from Chhattisgarh, India.

    Directory of Open Access Journals (Sweden)

    Pravin Kumar Jangde

    2015-09-01

    Full Text Available Background High speed motor vehicle accidents are on the rise over the past few years, a major cause of complex fractures of tibia. The main treatment aim of this type of fractures is reinstatement of the normal alignment and articular congruity. Although different surgical techniques are available, but minimally invasive plating osteosynthesis (MIPO is most popular in minimal articular comminution and damage of soft tissue envelope. MIPO advantages are no periosteal dissections, no disruption of hematoma, stable fixation, early mobilization, less complications and relatively higher rates of union. The main objective of this study was to evaluate the functional and clinical outcomes of distal tibia fracture patients, treated by internal fixation by MIPO technique with locking compression plate (LCP. Methods Twenty patients with closed distal tibia fracture with or without intra articular extension treated with MIPO with LCP were prospectively followed for average duration of 18.45 months (range 5-30 months. Fractures were classified according AO classification into broad types. Results Average duration of injury-surgery interval was 12days. The age incidence was an average of 38.95 yrs. High occurrence of fracture was seen in labourer (65%, maximum cases (50% mode of injury was due to road traffic accidents. 75% of the patients showed radiologic union in 13-16 weeks, full weight bearing was achieved in 13-16 weeks. Overall achievement was 75% excellent, 10% good, 10% fair and 5% with poor result. Conclusion The present study confirmed that MIPO with LCP is an effective and safe treatment method in terms of union time and complications rate for distal tibia fracture.

  17. Autologous chondrocyte transplantation for the treatment of articular cartilage defects in the knee joint. Techniques and results; Autologe Chondrozytentransplantation zur Behandlung von Knorpeldefekten des Kniegelenks. Techniken und Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Marlovits, S.; Kutscha-Lissberg, F.; Aldrian, S.; Resinger, C.; Singer, P.; Zeller, P.; Vecsei, V. [Universitaetsklinik fuer Unfallchirurgie, Medizinische Universitaet Wien (Austria)

    2004-08-01

    Currently the use of autologous chondrocytes as a cartilage-repair procedure for the repair of injured articular cartilage of the knee joint, is recommended. This review presents the technique of autologous chondrocyte transplantation (ACT) and their modifications as matrix-associated autologous chondrocyte transplantation (MACT). Beside the surgical procedure the experimental and clinical results are discussed. Furthermore the major complications and the indication guidelines are presented. Articular cartilage in adults has a poor ability to self-repair after a substantial injury. Surgical therapeutic efforts in treating cartilage defects have focused on bringing new cells capable of chondrogenesis into the lesions. With ACT good to excellent clinical results are seen in isolated posttraumatic lesions of the knee joint in the younger patient with the formation of hyalinelike repair tissue. The major complications are periosteal hypertrophy, delamination of the transplant, arthrofibrosis and transplant failure. The current limitations include osteoarthritic defects and higher patient age. With the right indication and operative technique ACT is an effective and save option for the treatment of large full thickness cartilage defect of the knee joint. (orig.) [German] Zur Behandlung umschriebener Defekte des artikulaeren Kniegelenkgelenkknorpels wird der Einsatz autologer Knorpelzellen zunehmend als neue biologische Methode empfohlen. Die Technik der autologen Chondrozytentransplantation (ACT) und deren Modifikationen als matrixassoziierte autologe Chondrozytentransplantation (MACT) werden dargestellt. Es erfolgt ein Ueberblick ueber die experimentellen und klinischen Ergebnisse mit der Darstellung der haeufigsten Komplikationen und den derzeit gueltigen Indikationsrichtlinien. Unter Verwendung qualitativ hochwertiger Zellen zeigen besonders posttraumatische Knorpeldefekte bei juengeren Patienten eine hohe Erfolgsquote mit der Ausbildung eines hyalinartigen

  18. Gene tree parsimony of multilocus snake venom protein families reveals species tree conflict as a result of multiple parallel gene loss.

    Science.gov (United States)

    Casewell, Nicholas R; Wagstaff, Simon C; Harrison, Robert A; Wüster, Wolfgang

    2011-03-01

    The proliferation of gene data from multiple loci of large multigene families has been greatly facilitated by considerable recent advances in sequence generation. The evolution of such gene families, which often undergo complex histories and different rates of change, combined with increases in sequence data, pose complex problems for traditional phylogenetic analyses, and in particular, those that aim to successfully recover species relationships from gene trees. Here, we implement gene tree parsimony analyses on multicopy gene family data sets of snake venom proteins for two separate groups of taxa, incorporating Bayesian posterior distributions as a rigorous strategy to account for the uncertainty present in gene trees. Gene tree parsimony largely failed to infer species trees congruent with each other or with species phylogenies derived from mitochondrial and single-copy nuclear sequences. Analysis of four toxin gene families from a large expressed sequence tag data set from the viper genus Echis failed to produce a consistent topology, and reanalysis of a previously published gene tree parsimony data set, from the family Elapidae, suggested that species tree topologies were predominantly unsupported. We suggest that gene tree parsimony failure in the family Elapidae is likely the result of unequal and/or incomplete sampling of paralogous genes and demonstrate that multiple parallel gene losses are likely responsible for the significant species tree conflict observed in the genus Echis. These results highlight the potential for gene tree parsimony analyses to be undermined by rapidly evolving multilocus gene families under strong natural selection.

  19. Revealing Rembrandt

    Directory of Open Access Journals (Sweden)

    Andrew J Parker

    2014-04-01

    Full Text Available The power and significance of artwork in shaping human cognition is self-evident. The starting point for our empirical investigations is the view that the task of neuroscience is to integrate itself with other forms of knowledge, rather than to seek to supplant them. In our recent work, we examined a particular aspect of the appreciation of artwork using present-day functional magnetic resonance imaging (fMRI. Our results emphasised the continuity between viewing artwork and other human cognitive activities. We also showed that appreciation of a particular aspect of artwork, namely authenticity, depends upon the co-ordinated activity between the brain regions involved in multiple decision making and those responsible for processing visual information. The findings about brain function probably have no specific consequences for understanding how people respond to the art of Rembrandt in comparison with their response to other artworks. However, the use of images of Rembrandt’s portraits, his most intimate and personal works, clearly had a significant impact upon our viewers, even though they have been spatially confined to the interior of an MRI scanner at the time of viewing. Neuroscientific studies of humans viewing artwork have the capacity to reveal the diversity of human cognitive responses that may be induced by external advice or context as people view artwork in a variety of frameworks and settings.

  20. The use of prediction models of spontaneous pregnancy in in vitro fertilization units reveals differences between the expected results of public and private clinics in Spain.

    Science.gov (United States)

    Gabbanini, Massimo; Privitera, Laura; Monzó, Ana; Higueras, Gemma; Fuster, Sonia; Garrido, Nicolás; Bosch, Ernesto; Pellicer, Antonio

    2010-11-01

    To evaluate the applicability of prediction models (PM) of spontaneous pregnancy (SP) in a population of infertile patients from a university-affiliated private assisted reproductive technology center (Instituto Valenciano de Infertilidad) and in the reproductive medicine section of a public university hospital (La Fe), both belonging to the same city (Valencia, Spain) between January and December 2008. We calculated the probability of SP using the PM developed by Hunault et al. in our two populations, and observed an estimated probability of SP<40% or the PM applicable in approximately 97% of the studied couples, and statistical differences between pregnancy probabilities in the two settings that were mainly a result of different age, sperm quality, and referral policies, leading us to conclude that the usefulness of PMs is limited in our environment. Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  1. Label-free porous silicon immunosensor for broad detection of opiates in a blind clinical study and results comparison to commercial analytical chemistry techniques.

    Science.gov (United States)

    Bonanno, Lisa M; Kwong, Tai C; DeLouise, Lisa A

    2010-12-01

    In this work, we evaluate for the first time the performance of a label-free porous silicon (PSi) immunosensor assay in a blind clinical study designed to screen authentic patient urine specimens for a broad range of opiates. The PSi opiate immunosensor achieved 96% concordance with liquid chromatography-mass spectrometry/tandem mass spectrometry (LC-MS/MS) results on samples that underwent standard opiate testing (n = 50). In addition, successful detection of a commonly abused opiate, oxycodone, resulted in 100% qualitative agreement between the PSi opiate sensor and LC-MS/MS. In contrast, a commercial broad opiate immunoassay technique (CEDIA) achieved 65% qualitative concordance with LC-MS/MS. Evaluation of important performance attributes including precision, accuracy, and recovery was completed on blank urine specimens spiked with test analytes. Variability of morphine detection as a model opiate target was <9% both within-run and between-day at and above the cutoff limit of 300 ng mL(-1). This study validates the analytical screening capability of label-free PSi opiate immunosensors in authentic patient samples and is the first semiquantitative demonstration of the technology's successful clinical use. These results motivate future development of label-free PSi technology to reduce complexity and cost of diagnostic testing particularly in a point-of-care setting.

  2. Evidence of Two Component Accretion Flows as revealed by time lag properties: Results of Long-Term RXTE/ASM Data Analysis

    Science.gov (United States)

    Ghosh, Arindam; Chakrabarti, Sandip Kumar

    2016-07-01

    Long-term RXTE/ASM X-ray data of several Galactic black hole candidates (BHCs) are analyzed. The results of this analysis show the existence of two component accretion flow (TCAF) in both low-mass and high-mass X-ray binaries (LMXBs & HMXBs). Large disks with long viscous timescales in the accreting matter with high angular momentum are prevalent in LMXBs due to processes like Roche lobe overflow, while small disks with little viscous delays are observed in HMXBs, primarily because of wind accretion. Two parameters are defined as photon indices, independent of the choice of a BHC, in order to find correlation between the two components, namely, the Keplerian disk component and the sub-Keplerian component, thereby estimating the time lag between two aforesaid timescales. Fluxes of hard and soft photons are observed to be anti-correlated with respect to these photon indices. The time lags give us an idea of the viscosity in the Keplerian component.

  3. Landscape genetics reveals inbreeding and genetic bottlenecks in the extremely rare short-globose cacti Mammillaria pectinifera (Cactaceae as a result of habitat fragmentation

    Directory of Open Access Journals (Sweden)

    Reyna Maya-García

    2017-02-01

    Full Text Available Mammillaria pectinifera is an endemic, short-globose cactus species, included in the IUCN list as a threatened species with only 18 remaining populations in the Tehuacán-Cuicatlán Valley in central Mexico. We evaluated the population genetic diversity and structure, connectivity, recent bottlenecks and population size, using nuclear microsatellites. M. pectinifera showed high genetic diversity but some evidence of heterozygote deficiency (FIS, recent bottlenecks in some populations and reductions in population size. Also, we found low population genetic differentiation and high values of connectivity for M. pectinifera, as the result of historical events of gene flow through pollen and seed dispersal. M. pectinifera occurs in sites with some degree of disturbance leading to the isolation of its populations and decreasing the levels of gene flow among them. Excessive deforestation also changes the original vegetation damaging the natural habitats. This species will become extinct if it is not properly preserved. Furthermore, this species has some ecological features that make them more vulnerable to disturbance such as a very low growth rates and long life cycles. We suggest in situ conservation to prevent the decrease of population sizes and loss of genetic diversity in the natural protected areas such as the Tehuacán-Cuicatlán Biosphere Reserve. In addition, a long-term ex situ conservation program is need to construct seed banks, and optimize seed germination and plant establishment protocols that restore disturbed habitats. Furthermore, creating a supply of living plants for trade is critical to avoid further extraction of plants from nature.

  4. Pilot Study on Folate Bioavailability from A Camembert Cheese reveals contradictory findings to recent results from a Human Short-term study

    Directory of Open Access Journals (Sweden)

    Sabine eMönch

    2016-04-01

    Full Text Available Different dietary sources of folate have differing bioavailabilities which may affect their nutritional value. In order to examine if these differences also occur within the same food products, a short term human pilot study was undertaken as a follow-up study to a previously published human trial to evaluate the relative native folate bioavailabilities from low-fat Camembert cheese compared to pteroylmonoglutamic acid as the reference dose. Two healthy human subjects received the test foods in a randomized cross-over design separated by a 14-day equilibrium phase. Folate body pools were saturated with a pteroylmonoglutamic acid supplement before the first testing and between the testings. Folates in test foods and blood plasma were analysed by stable isotope dilution assays. The biokinetic parameters Cmax, tmax and AUC were determined in plasma within the interval of 0 to 12 hours. When comparing the ratio estimates of AUC and Cmax for the different Camembert cheeses, a higher bioavailability was found for the low-fat Camembert assessed in the present study (≥64% compared to a different brand in our previous investigation (8.8%. It is suggested that these differences may arise from the different folate distribution in the soft dough and firm rind as well as differing individual folate vitamer proportions. The results clearly underline the importance of the food matrix, even within the same type of food product, in terms of folate bioavailability. Moreover, our findings add to the increasing number of studies questioning the general assumption of 50 % bioavailability as the rationale behind the definition of folate equivalents. However, more research is needed to better understand the interactions between individual folate vitamers and other food components and the potential impact on folate bioavailability and metabolism.

  5. Pilot Study on Folate Bioavailability from a Camembert Cheese Reveals Contradictory Findings to Recent Results from a Human Short-term Study.

    Science.gov (United States)

    Mönch, Sabine; Netzel, Michael; Netzel, Gabriele; Ott, Undine; Frank, Thomas; Rychlik, Michael

    2016-01-01

    Different dietary sources of folate have differing bioavailabilities, which may affect their nutritional "value." In order to examine if these differences also occur within the same food products, a short-term human pilot study was undertaken as a follow-up study to a previously published human trial to evaluate the relative native folate bioavailabilities from low-fat Camembert cheese compared to pteroylmonoglutamic acid as the reference dose. Two healthy human subjects received the test foods in a randomized cross-over design separated by a 14-day equilibrium phase. Folate body pools were saturated with a pteroylmonoglutamic acid supplement before the first testing and between the testings. Folates in test foods and blood plasma were analyzed by stable isotope dilution assays. The biokinetic parameters C max, t max, and area under the curve (AUC) were determined in plasma within the interval of 0-12 h. When comparing the ratio estimates of AUC and C max for the different Camembert cheeses, a higher bioavailability was found for the low-fat Camembert assessed in the present study (≥64%) compared to a different brand in our previous investigation (8.8%). It is suggested that these differences may arise from the different folate distribution in the soft dough and firm rind as well as differing individual folate vitamer proportions. The results clearly underline the importance of the food matrix, even within the same type of food product, in terms of folate bioavailability. Moreover, our findings add to the increasing number of studies questioning the general assumption of 50% bioavailability as the rationale behind the definition of folate equivalents. However, more research is needed to better understand the interactions between individual folate vitamers and other food components and the potential impact on folate bioavailability and metabolism.

  6. Total hip replacement using hemi-circumferential interposition acetabuloplasty for acetabular deficiency in post-Perthes deformities: technique and long-term results

    NARCIS (Netherlands)

    D. Haverkamp; H. Eijer; R.K. Marti

    2006-01-01

    We describe a technique of hemi-circumferential interposition grafting that allows placement of the cup in the anatomical position of the original acetabulum in the rare cases of post-Perthes or Perthes-like deformities of the femoral head combined with a steep and shallow acetabulum. This technique

  7. Resultados de la técnica stop and chop en la facoemulsificación Results of stop and chop technique in phacoemulsification

    Directory of Open Access Journals (Sweden)

    Juan Raúl Hernández Silva

    2010-06-01

    Full Text Available OBJETIVOS: Describir los resultados morfofuncionales alcanzados con la técnica stop and chop en la cirugía de catarata por facoemulsificación (faco, en el Centro de Microcirugía Ocular del Instituto Cubano de Oftalmología "Ramón Pando Ferrer" entre Junio de 2006 y Marzo de 2009. MÉTODOS: Se realizó un estudio descriptivo, transversal en el cual el universo y la muestra del trabajo lo constituyeron todos los pacientes con diagnóstico de catarata presenil y senil, quienes cumplían con los criterios de selección y aceptaron someterse a la técnica quirúrgica señalada, lo cual correspondió a 201 ojos operados. Estos datos se analizaron a través de tablas de contingencia con frecuencias absolutas y relativas; además se emplearon medias con el uso del programa de procesamiento de datos SPSS versión 11.1, donde se aplicó la prueba t de student para su comparación. RESULTADOS: Se encontró que la catarata predominó en mayores de 70 años en el 33,4 % de los pacientes. La mejor agudeza visual con corrección obtenida se incrementó hasta siete líneas en la escala de Snellen en el 93,0 % de los casos; el cilindro refractivo apenas se modificó en 0,15 dioptrías; la pérdida de células endoteliales fue de 8,2 % y las complicaciones operatorias fueron de 1,5 %. CONCLUSIONES: La edad de los pacientes sometidos a cirugía de catarata por la técnica de stop and chop fue en su mayoría de más de 70 años. La MAVC posoperatoria ganó hasta siete líneas en la escala de Snellen; el astigmatismo que se indujo en la cirugía fue menor de media dioptría; la pérdida celular y las complicaciones posoperatorias no fueron significativas.OBJECTIVES: To describe the morphofunctional results of the stop and chop technique in cataract surgery in phacoemulsification at the Eye Microsurgery Center of "Ramón Pando Ferrer" Cuban Institute of Ophthalmology from June 2006 to March 2009. METHODS: A cross-sectional descriptive study was conducted. The

  8. Plastia da valva mitral com a técnica do "Duplo Teflon": resultados de 10 anos Mitral valve repair with "Double Teflon" technique: 10-year results

    Directory of Open Access Journals (Sweden)

    Carlos Manuel de Almeida Brandão

    2007-12-01

    Full Text Available OBJETIVO: O objetivo deste trabalho é apresentar os resultados clínicos tardios da plástica da valva mitral com a técnica do "Duplo Teflon". MÉTODOS: A plástica de "Duplo Teflon" consiste em técnica de reparo mitral com ressecção quadrangular da cúspide posterior, anuloplastia segmentar com plicatura do anel com de fios com "pledgets" sobre uma tira de Teflon, e sutura borda a borda da cúspide. Entre abril de 1994 e dezembro de 2003, 133 pacientes com diagnóstico de insuficiência mitral degenerativa com alongamento ou rotura de cordas da cúspide posterior foram submetidos à plástica com esta técnica. A idade média foi de 60,4 anos e 60,9% eram do sexo feminino. Quanto à avaliação clínica no pré-operatório, 29,3% dos pacientes estavam em classe funcional IV, 55,7% em classe III e 15,0% em classe II. Técnicas associadas de plástica mitral foram utilizadas em 15,2% dos pacientes, sendo a mais comum o encurtamento de cordas. Vinte e seis (19,5% pacientes foram submetidos a operações associadas. RESULTADOS: Houve um (0,75% óbito hospitalar. No período pós-operatório tardio, 95,5% dos sobreviventes estavam em classe funcional I. As taxas linearizadas de tromboembolismo, reoperação e óbito foram 0,9%, 0,3% e 0,6% pacientes/ano, respectivamente. A sobrevida atuarial em 10 anos foi de 94,1% ± 3,6%. As sobrevidas atuariais livre de tromboembolismo e reoperação foram de 97,3 ± 1,5% e 99,2 ± 0,8%, respectivamente. Não houve casos de endocardite ou hemólise. CONCLUSÃO: A plástica da valva mitral com a técnica do "Duplo Teflon" apresenta baixa morbi-mortalidade e boa evolução clínica tardia.OBJECTIVE: The purpose of this paper is to present the late clinical results of mitral valve repair with the "Double Teflon" technique. METHODS: "Double Teflon" technique consists of a quadrangular resection of the posterior leaflet, annulus plication with "pledgetted" stitches over a Teflon patch, and leaflet suture. Between

  9. Saturation of superstorms and finite compressibility of the magnetosphere: Results of the magnetogram inversion technique and global PPMLR-MHD model

    Science.gov (United States)

    Mishin, V. V.; Mishin, V. M.; Karavaev, Yu.; Han, J. P.; Wang, C.

    2016-07-01

    We report on novel features of the saturation process of the polar cap magnetic flux and Poynting flux into the magnetosphere from the solar wind during three superstorms. In addition to the well-known effect of the interplanetary electric (Esw) and southward magnetic (interplanetary magnetic field (IMF) Bz) fields, we found that the saturation depends also on the solar wind ram pressure Pd. By means of the magnetogram inversion technique and a global MHD numerical model Piecewise Parabolic Method with a Lagrangian Remap, we explore the dependence of the magnetopause standoff distance on ram pressure and the southward IMF. Unlike earlier studies, in the considered superstorms both Pd and Bz achieve extreme values. As a result, we show that the compression rate of the dayside magnetosphere decreases with increasing Pd and the southward Bz, approaching very small values for extreme Pd ≥ 15 nPa and Bz ≤ -40 nT. This dependence suggests that finite compressibility of the magnetosphere controls saturation of superstorms.

  10. Radiotherapy for treatment of bursitis. Indication, technique, own results, literature survey; Strahlentherapie bei der Periarthropathia humeroscapularis (PHS). Indikation, Technik, eigene Ergebnisse, Literaturuebersicht

    Energy Technology Data Exchange (ETDEWEB)

    Heyd, R. [Staedtische Kliniken Offenbach am Main (Germany). Strahlenklinik]|[Frankfurt Univ. (Germany). Klinik fuer Strahlentherapie und Onkologie; Schopohl, B.; Boettcher, H.D. [Frankfurt Univ. (Germany). Klinik fuer Strahlentherapie und Onkologie

    1998-12-31

    Our own experience covers 41 primarily chronic cases. The patients have been irradiated with a telecobalt device with isocentric opposing fields, receiving 4x1.0 Gy within two weeks; 15 patients (36.6%) received a second radiation treatment (8 Gy), and one patient (2.4%) a third (12 Gy). After a follow-up period of 44 months on the average, the results were: Complete remittence of pain in 44%, abatement of pain in 44%, and no effect in 12%. Improvement of shoulder joint motility was achieved in 78%. The rate of recidivation was as low as 3%. A statistical evaluation of data acquired revealed that the prognosis is worst in case of a long period of pain preceding commencement of radiotherapy, combined with intensive prior therapy. (orig./CB) [Deutsch] In einer eigenen Untersuchung wurden 41 ueberwiegend chronische Faelle mit 4x1,0 Gy in 2 Wochen an einem Telekobaltgeraet mit isozentrischen Gegenfeldern behandelt, 15 (36,6%) erhielten eine 2. Bestrahlungsserie (8 Gy), ein Fall (2,4%) eine Dritte (12 Gy). Nach einem Nachbeobachtungszeitraum von median 44 Monaten fand sich bei 44% eine komplette Schmerzremission, bei 44% eine Linderung und 12% waren ohne einen Einfluss der Behandlung. Eine Verbesserung der Motilitaet des Schultergelenkes wurde bei 78% erreicht. Die Rezidivrate lag bei nur 3%. Nach statistischer Bearbeitung der Daten erwies sich die Kombination einer langen Beschwerdedauer vor Einleitung der Radiotherapie und intensiver Vortherapie als prognostisch unguenstiger (p=0,02). (orig.)

  11. Ambiguity Revealed

    OpenAIRE

    Subir Bose; Matthew Polisson; Ludovic Renou

    2012-01-01

    We derive necessary and suffcient conditions for data sets composed of state-contingent prices and consumption to be consistent with two prominent models of decision making under ambiguity: variational preferences and smooth ambiguity. The revealed preference conditions for the maxmin expected utility and subjective expected utility models are characterized as special cases.

  12. Ambiguity revealed

    OpenAIRE

    Bayer, Ralph-C; Bose, Subir; Polisson, Matthew; Renou, Ludovic

    2013-01-01

    We derive necessary and sufficient conditions for data sets composed of state-contingent prices and consumption to be consistent with two prominent models of decision making under uncertainty: variational preferences and smooth ambiguity. The revealed preference conditions for subjective expected utility, maxmin expected utility, and multiplier preferences are characterised as special cases. We implement our tests on data from a portfolio choice experiment.

  13. Behavioral Risk Profile of Men Who Have Sex with Men in Beijing, China: Results from a Cross-sectional Survey with Randomized Response Techniques

    Institute of Scientific and Technical Information of China (English)

    Guo-Zhu Geng; Ge Gao; Yu-Hua Ruan; Ming-Run Yu; Yun-Hua Zhou

    2016-01-01

    Background:Human immunodeficiency virus (HIV) is spreading rapidly among men who have sex with men (MSM) in China.Anonymous questionnaires or direct interviews have been frequently used to study their behavior.The aim of the study was to describe the behavioral risk profile of the MSM in Beijing using the randomized response techniques (RRTs).Methods:A cross-sectional survey of sexual behavior among a sample of MSM was conducted in two HIV counseling and testing clinics in Beijing.The survey was carried out with an anonymous questionnaire containing sensitive questions on sexual behavior.To obtain the honest responses to the sensitive questions,three distinctive RRTs were used in the questionnaire:(1) Additive randomized response model for quantitative questions,(2) randomized response model for multiple choice questions,and (3) Simmons randomized response model for binomial questions.Formulae for the point estimate,variance,and confidence interval (CI) were provided for each specific model.Results:Using RRTs in a sample of 659 participants,the mean age at first homosexual encounter was estimated to be 21.7 years (95% CI:21.2-22.2),and each had sex with about three (2.9,95% CI:2.4-3.4) male partners on average in the past month.The estimated rate for consistent condom use was 56.4% (95% CI:50.1-62.8%).In addition,condom was estimated to be used among 80.0% (95% CI:74.1-85.9%) of the population during last anal sex with a male partner.Conclusions:Our study employed RRTs in a survey containing questions on sexual behavior among MSM,and the results showed that RRT might be a useful tool to obtain truthful feedback on sensitive information such as sexual behavior from the respondents,especially in traditional Chinese cultural settings.

  14. Apocalypto: revealing lost text with XMT

    Science.gov (United States)

    Mills, David; Davis, Graham R.; Lai, Yu-kun; Rosin, Paul

    2014-09-01

    "Can brute-force high-contrast tomography techniques and image processing techniques retrieve textual content from damaged heritage materials?" The Dental Institute at Queen Mary University of London (QMUL) is the leading centre for very high contrast X-Ray Microtomography imaging. The Apocalypto Project is our collaboration with the heritage community and experts in Computer Vision systems in the Computer Science Department at Cardiff University. This collaboration has developed techniques and a workflow that allows us to reveal textual content from moisture-damaged parchment rolls. This article will also present some initial results from burned and heat shrunken parchment rolls, an insect damaged Mamluk cap and a birch bark roll.

  15. Mathematics revealed

    CERN Document Server

    Berman, Elizabeth

    1979-01-01

    Mathematics Revealed focuses on the principles, processes, operations, and exercises in mathematics.The book first offers information on whole numbers, fractions, and decimals and percents. Discussions focus on measuring length, percent, decimals, numbers as products, addition and subtraction of fractions, mixed numbers and ratios, division of fractions, addition, subtraction, multiplication, and division. The text then examines positive and negative numbers and powers and computation. Topics include division and averages, multiplication, ratios, and measurements, scientific notation and estim

  16. Aneurisma paraclinóideo: técnica cirúrgica e resultados em 51 pacientes Paraclinoid aneurysms: surgical technique and results in 51 patients

    Directory of Open Access Journals (Sweden)

    Roberto Leal Silveira

    2004-06-01

    Full Text Available Analisam-se 51 pacientes portadores de 55 aneurismas paraclinóideos (APC submetidos a tratamento cirúrgico. Em decorrência de tratar-se de procedimento de alta complexidade, descrevemos em pormenor os seus aspectos técnicos. O processo clinóideo anterior foi removido por via extradural após secção da duplicação dural da tenda da fissura orbitária superior e/ou por via intradural. Conseguiu-se exclusão do APC nos 51 pacientes. Em dois casos a clipagem foi parcial e, em três, ocorreu oclusão da ACI. Em 42 (82% pacientes ocorreu bom resultado; em 5 (10%, incapacidade moderada; em 1 (2%, incapacidade grave e três (6% faleceram por infarto cerebral. Sete (13,7% pacientes tiveram lesão adicional do nervo óptico, sendo parcial em 4 (7,7% e total em 3 (6%.An analysis of the surgical results of 51 patients harboring 55 paraclinoid aneurysms is performed, along with a throughoutful description of it’s complex microsurgical technique. The anterior clinoid process was removed by the extradural route after sectioning the dural duplication between the superior orbital fissure and the dura of the temporal lobe, and/or by the intradural approach. All 55 aneurysms was excluded. In two cases the clipping was partial and the internal carotid artery were ocluded in three cases. The surgical outcome was good in 42 (82% patients, moderate incapacity occurred in five (10% and severe incapacity in one patient (2%. Three patients (6% died due to brain infarction. Seven patients (13,7% had adicional lesion of the optic nerve, being partial in 4 (7,7% and total in 3 (6%.

  17. Anterior single odontoid screw placement for type II odontoid fractures: our modified surgical technique and initial results in a cohort study of 15 patients

    Science.gov (United States)

    Munakomi, Sunil; Tamrakar, Karuna; Chaudhary, Pramod Kumar; Bhattarai, Binod

    2016-01-01

    Objective: Anterior odontoid screw fixation for type II odontoid fracture is the ideal management option. However in the context of unavailability of an O-arm or neuro-navigation and poor images from the available C-arm may be an obstacle to ideal trajectory and placement of the odontoid screw. We herein detail  our surgical technique so as to ensure a correct trajectory and subsequent good fusion in Type II odontoid fractures. This may be advantageous  in clinical set ups lacking state of the art facilities.  Methods and Results: In this cohort study we included 15 consecutive patients who underwent anterior odontoid screw placement. We routinely dissect the longus colli to completely visualize the entire width of C3 body. We then perform a median C2-C3 disectomy followed by creating a gutter in the superior end of C3 body. We then guide the Kirchsner (K) wire purchasing adequate anterior cortex of C2. Rest of the procedure follows the similar steps as described for odontoid screw placement. We achieved 100% correct trajectory and screw placement in our study. There were no instances of screw break out, pull out or nonunion. There was one patient mortality following myocardial infarction in our study. Conclusion: Preoperative imaging details, proper patient positioning, meticulous dissection, thorough anatomical knowledge and few added surgical nuances are the cornerstones in ideal odontoid screw placement. This may be pivotal in managing  patients in developing nations having rudimentary neurosurgical set up. PMID:27990259

  18. Clinical observation and quality of life in terms of nasal sinusitis after radiotherapy for nasopharyngeal carcinoma: long-term results from different nasal irrigation techniques

    Science.gov (United States)

    Luo, H-H; Fu, Z-C; Liao, S-G; Li, D-S

    2014-01-01

    Objective: The aim of our study was to investigate the relationship between nasal irrigation techniques (NIT) and the survival rate and the quality of life (QOL) in patients with nasal sinusitis (NS). Methods: We studied data from 1134 patients with nasopharyngeal carcinoma (NPC) who received radical radiotherapy, which were randomly divided into three groups (A, B and C). Group A used nasal irrigator; Group B used homemade nasal irrigation (NI) connector combined with enemator; and Group C used nasal sprayer. The clinical effects, 5-year overall survival (OS) and progression-free survival (PFS) were observed. Furthermore, the QOL in patients with NS was evaluated using the Sino-Nasal Outcome Test 20. Results: The median follow-up time was 69 months. The 5-year OS and PFS were 80.5% and 73.2%, respectively, for all patients. There was no significant difference in OS, PFS, xerostomia and neck skin toxicity grade 3 and greater among groups. There was no difference among groups. The incidence of NS was the highest in group C. Conclusion: The symptoms of NS seriously affected the QOL period of 1 year. Group C showed no improvement during the follow-up period, which for A and B, by contrast, had after 1 year. Although the exact mechanism remains to be explored in NIT, our findings suggest that patients with NPC should nasal irrigate for 2 years after radiotherapy. Advances in knowledge: Our study shows that a nasal irrigator is necessary for patients with NPC for a high QOL in terms of NS. PMID:24814695

  19. Imaged-guided liver stereotactic body radiotherapy using VMAT and real-time adaptive tumor gating. Concerns about technique and preliminary clinical results.

    Science.gov (United States)

    Llacer-Moscardo, Carmen; Riou, Olivier; Azria, David; Bedos, Ludovic; Ailleres, Norbert; Quenet, Francois; Rouanet, Philippe; Ychou, Marc; Fenoglietto, Pascal

    2017-01-01

    Motion management is a major challenge in abdominal SBRT. We present our study of SBRT for liver tumors using intrafraction motion review (IMR) allowing simultaneous KV information and MV delivery to synchronize the beam during gated RapidArc treatment. Between May 2012 and March 2015, 41 patients were treated by liver SBRT using gated RapidArc technique in a Varian Novalis Truebeam STx linear accelerator. PTV was created by expanding 5 mm from the ITV. Dose prescription ranged from 40 to 50 Gy in 5-10 fractions. The prescribed dose and fractionation were chosen depending on hepatic function and dosimetric results. Thirty-four patients with a minimal follow-up of six months were analyzed for local control and toxicity. Accuracy for tumor repositioning was evaluated for the first ten patients. With a median follow-up of 13 months, the treatment was well tolerated and no patient presented RILD, perforation or gastrointestinal bleeding. Acute toxicity was found in 3 patients with G1 abdominal pain, 2 with G1 nausea, 10 with G1 asthenia and 1 with G2 asthenia. 6 patients presented asymptomatic transitory perturbation of liver enzymes. In-field local control was 90.3% with 7 complete responses, 14 partial responses and 7 stabilisations. 3 patients evolved "in field". 12 patients had an intrahepatic progression "out of field". Mean intrafraction deviation of fiducials in the craneo-caudal direction was 0.91 mm (0-6 mm). The clinical tolerance and oncological outcomes were favorable when using image-guided liver SBRT with real-time adaptive tumor gating.

  20. Theory-based interventions combining mental simulation and planning techniques to improve physical activity: Null results from two randomized controlled trials

    Directory of Open Access Journals (Sweden)

    Carine Meslot

    2016-11-01

    Full Text Available Interventions to assist individuals in initiating and maintaining regular participation in physical activity are not always effective. Psychological and behavioural theories advocate the importance of both motivation and volition in interventions to change health behaviour. Interventions adopting self-regulation strategies that foster motivational and volitional components may, therefore, have utility in promoting regular physical activity participation. We tested the efficacy of an intervention adopting motivational (mental simulation and volitional (implementation intentions components to promote a regular physical activity in two studies. Study 1 adopted a cluster randomised design students in which participants (n=92 were allocated to one of three conditions: mental simulation plus implementation intention, implementation intention only, or control. Study 2 adopted a 2 (mental simulation vs. no mental simulation x 2 (implementation intention vs. no implementation intention randomised controlled design in which fitness centre attendees (n=184 were randomly allocated one of four conditions: mental simulation only, implementation intention only, combined, or control. Physical activity behaviour was measured by self-report (Study 1 or fitness centre attendance (Study 2 at 4- (Studies 1 and 2 and 19- (Study 2 only week follow-up periods. Findings revealed no statistically significant main or interactive effects of the mental simulation and implementation intention conditions on physical activity outcomes in either study. Despite adopting protocols consistent with previous research, utilizing objective behavioural measures, and having sufficient statistical power, results provide evidence that, in contrast to previous findings, the motivational and volitional components are not effective in changing physical activity behaviour. Future research should focus on the format of the intervention components, test the effects of each component alone and

  1. Recanalization strategy for chronic total occlusions with tapered and stiff-tip guidewire. The results of CTO new techniQUE for STandard procedure (CONQUEST) trial.

    Science.gov (United States)

    Mitsudo, Kazuaki; Yamashita, Takehiro; Asakura, Yasushi; Muramatsu, Toshiya; Doi, Osamu; Shibata, Yoshisato; Morino, Yoshihiro

    2008-11-01

    The success rate of percutaneous coronary intervention (PCI) for chronic total coronary occlusion (CTO) lesions varies depending on the guidewire manipulation skills of the operator. The standardization of guidewire technique is very important. A new technique with a new tapered wire (Conquest, Confianza Pro) was tested to verify effectiveness for higher initial success rates and standardization of PCI for CTO. A prospective, multicenter registry was conducted at 6 investigational sites. In the CONQUEST trial, The CTO lesions were treated by using an intermediate guidewire to cross the lesion. If it did not cross, the guidewire was changed to the Conquest guidewire. If it did not cross, "seesaw-wiring" or the "parallel-wire technique" was performed. The primary endpoint was the initial procedural success rate. A total of 110 patients representing 116 CTO lesions were treated from July 2003 through March 2004. The procedural success rate was 86.2% on the first try, and 88.8% on the second try, respectively. The guidewire success rate on the second try was 90.5% during the hospital stay; no deaths, or acute myocardial infarctions were confirmed. Two patients deteriorated into tamponade, and surgical or percutaneous drainage was performed in each patient without any sequelae. A guidewire technique in PCI for CTOs that starts with the intermediate guidewire and moves to the Confianza Pro tapered guidewire, either alone or by performing a see-saw or parallel-wire technique, can achieve a high initial success rate with an acceptably low major complication rate.

  2. Real-Time Pretreatment Review Limits Unacceptable Deviations on a Cooperative Group Radiation Therapy Technique Trial: Quality Assurance Results of RTOG 0933

    Energy Technology Data Exchange (ETDEWEB)

    Gondi, Vinai, E-mail: vgondi@chicagocancer.org [Cadence Brain Tumor Center and CDH Proton Center, Warrenville, Illinois (United States); University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin (United States); Cui, Yunfeng [Duke University School of Medicine, Durham, North Carolina (United States); Mehta, Minesh P. [University of Maryland School of Medicine, Baltimore, Maryland (United States); Manfredi, Denise [Radiation Therapy Oncology Group—RTQA, Philadelphia, Pennsylvania (United States); Xiao, Ying; Galvin, James M. [Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (United States); Rowley, Howard [University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin (United States); Tome, Wolfgang A. [Montefiore Medical Center and Institute for Onco-Physics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York (United States)

    2015-03-01

    Purpose: RTOG 0933 was a phase II trial of hippocampal avoidance during whole brain radiation therapy for patients with brain metastases. The results demonstrated improvement in short-term memory decline, as compared with historical control individuals, and preservation of quality of life. Integral to the conduct of this trial were quality assurance processes inclusive of pre-enrollment credentialing and pretreatment centralized review of enrolled patients. Methods and Materials: Before enrolling patients, all treating physicians and sites were required to successfully complete a “dry-run” credentialing test. The treating physicians were credentialed based on accuracy of magnetic resonance imaging–computed tomography image fusion and hippocampal and normal tissue contouring, and the sites were credentialed based on protocol-specified dosimetric criteria. Using the same criteria, pretreatment centralized review of enrolled patients was conducted. Physicians enrolling 3 consecutive patients without unacceptable deviations were permitted to enroll further patients without pretreatment review, although their cases were reviewed after treatment. Results: In all, 113 physicians and 84 sites were credentialed. Eight physicians (6.8%) failed hippocampal contouring on the first attempt; 3 were approved on the second attempt. Eight sites (9.5%) failed intensity modulated radiation therapy planning on the first attempt; all were approved on the second attempt. One hundred thirteen patients were enrolled in RTOG 0933; 100 were analyzable. Eighty-seven cases were reviewed before treatment; 5 (5.7%) violated the eligibility criteria, and 21 (24%) had unacceptable deviations. With feedback, 18 cases were approved on the second attempt and 2 cases on the third attempt. One patient was treated off protocol. Twenty-two cases were reviewed after treatment; 1 (4.5%) violated the eligibility criteria, and 5 (23%) had unacceptable deviations. Conclusions: Although >95% of the

  3. Effectiveness of control techniques in drinking water installations. Survey of recent scientific research results; Effectiviteit beheerstechnieken in drinkwaterinstallaties. RIVM inventariseert recente wetenschappelijke bevindingen

    Energy Technology Data Exchange (ETDEWEB)

    Scheffer, W.

    2012-12-15

    A literature survey has been carried out on current scientific knowledge about the effectiveness of management techniques for Legionella in potable water systems. The examined scientific literature from 2007-201 comprises mainly case studies on the effect of the introduction of a certain management technique on Legionella growth [Dutch] Het RIVM heeft in opdracht van de Inspectie Leefomgeving en Transport (ILT) literatuuronderzoek gedaan naar de huidige wetenschappelijke kennis over de effectiviteit van beheerstechnieken voor legionella in drinkwaterinstallaties. De onderzochte wetenschappelijke literatuur uit 2007-201 I betreft vooral casestudies naar het effect van de introductie van een bepaalde beheerstechniek op de legionellagroei.

  4. REVEALED ALTRUISM

    OpenAIRE

    Cox, James C; Friedman, Daniel; Sadiraj, Vjollca

    2009-01-01

    This pap er develops a theory of revealed preferences over oneís own and othersímonetary payo§s. We intro duce ìmore altruistic thanî(MAT), a partial ordering over preferences, and interpret it with known parametric mo dels. We also intro duce and illustrate ìmore generous thanî (MGT), a partial ordering over opp ortunity sets. Several recent discussions of altruism fo cus on two player extensive form games of complete information in which the Örst mover (FM) cho oses a more or less gen...

  5. Fechamento de canal arterial por minitoracotomia: técnica e resultados Patent ductus arteriosus (PDA closure with minithoracotomy: technique and results

    Directory of Open Access Journals (Sweden)

    Pedro R. SALERNO

    2000-09-01

    Full Text Available CASUÍSTICA E MÉTODOS: No período de novembro de 1996 a dezembro de 1997, 15 crianças portadoras de canal arterial (CA, sendo 12 do sexo feminino, com idade média de 2,7 anos, peso médio de 13,9 kg foram submetidas a fechamento do CA por minitoracotomia. O ecodopplercardiograma confirmou o diagnóstico em todos o casos e mostrou o diâmetro do CA entre 2 mm e 10 mm, com média de 4,06 mm. A indicação cirúrgica foi eletiva em todos os casos. A operação consistiu de minitoracotomia esquerda no 4º espaço intercostal de 2,5 cm a 3,0 cm, seguida de dissecção do CA e clipagem do mesmo com 2 clips metálicos. Não foi utilizada drenagem pleural em nenhum dos casos. RESULTADOS: Todos os pacientes receberam alta em média no 4º dia de pós-operatório, sem nenhum escape pelo CA ao ecodopplercardiograma. CONCLUSÃO: O fechamento de CA por minitoracotomia é uma alternativa de tratamento que reduz o período de internação, bom efeito cosmético e baixo índice de complicações.OBJECTIVE:The purpose of this study was to describe a new technique for closure of patent ductus arteriosus (PDA by minithoracotomy (2.5 a 3.0 cm and clipping the PDA with titanium clips. MATERIAL AND METHODS: From November 1996 to December 1997, 15 children with PDA underwent surgical closure. The mean age at the time of operation was 2.7 years, mean weight was 13.9 kg. The procedure was through a left minithoracotomy at the 4º intercostal space. The ductus was identified, dissected and isolated. Interruption of ductal flow was performed by direct clipping with two clips. The chest was closed without a chest drain. Unless the patient was ventilator dependent before the closure, the child usually was extubated in the operating room. RESULTS: Color doppler echocardiography demonstrated total occlusion of the ductus in all patients. All 15 patients were discharged from the hospital on the 4º postoperative day (mean. CONCLUSION: We conclude that surgical closure of

  6. Tests of heat techniques in households. Analysis of the results of the field tests; Praktijkprestaties van warmtetechnieken bij huishoudens. Analyse resultaten veldtesten

    Energy Technology Data Exchange (ETDEWEB)

    De Jong, A.; Friedel, P.; Overman, P. [Energy Matters, Driebergen (Netherlands)

    2012-11-15

    The development within conventional techniques and new techniques for the recovery and generation of heat in the house construction industry led to a need for knowledge of efficiencies of those techniques in practice. Therefore a project has been set up to gain insight into the efficiencies. In the field tests, five heat techniques are investigated: high-efficiency boilers, solar water heaters, balanced ventilation systems with heat recovery (also called heat recovery systems) and heat pump water heaters [Dutch] De ontwikkeling binnen conventionele technieken en nieuwe technieken voor de terugwinning en opwekking van warmte in de woningbouw leidden ertoe dat er bij verschillende partijen in de keten een kennisbehoefte is ontstaan naar de rendementen van deze technieken in de praktijk. Daartoe heeft AgentschapNL een project opgezet om meer inzicht te verkrijgen in deze rendementen. In de veldtesten worden vijf warmtechnieken bekeken: HR-ketels, HRe-ketels, zonneboilers, gebalanceerde ventilatiesystemen met warmteterugwinning (verder WTW-systemen genoemd) en warmtepompboilers. Deze worden op minutenbasis bemeten.

  7. Using the Oaxaca-Blinder Decomposition Technique to Analyze Learning Outcomes Changes over Time: An Application to Indonesia's Results in PISA Mathematics. Policy Research Working Paper 5584

    Science.gov (United States)

    Barrera-Osorio, Felipe; Garcia-Moreno, Vicente; Patrinos, Harry Anthony; Porta, Emilio

    2011-01-01

    The Oaxaca-Blinder technique was originally used in labor economics to decompose earnings gaps and to estimate the level of discrimination. It has been applied since in other social issues, including education, where it can be used to assess how much of a gap is due to differences in characteristics (explained variation) and how much is due to…

  8. Interpretation of results from on-farm experiments: manure-nitrogen recovery on grassland as affected by manure quality and application technique. 1. An agronomic analysis

    NARCIS (Netherlands)

    Groot, J.C.J.; Ploeg, van der J.D.; Verhoeven, F.P.M.; Lantinga, E.A.

    2007-01-01

    In a 5-year field experiment, a comparison was made between the manure application practices of two adjacent dairy farms in the north of the Netherlands. Grassland management systems at Drogeham and Harkema contrasted in manure application technique (surface application versus shallow injection,

  9. Results of Using the Take-Away Technique on Students' Achievements and Attitudes in High School Physics and Physical Science Courses

    Science.gov (United States)

    Carifio, James; Doherty, Michael

    2012-01-01

    The Take-away Technique was used in High School Physics and Physical Science courses for the unit on Newtonian mechanics in a teacher (6) by grade level (4) partially crossed design (N = 272). All classes received the same IE instructional treatment. The experimental group (classrooms) did a short Take-away after each class summarizing the key…

  10. Machine-assisted verification of latent fingerprints: first results for nondestructive contact-less optical acquisition techniques with a CWL sensor

    Science.gov (United States)

    Hildebrandt, Mario; Kiltz, Stefan; Krapyvskyy, Dmytro; Dittmann, Jana; Vielhauer, Claus; Leich, Marcus

    2011-11-01

    A machine-assisted analysis of traces from crime scenes might be possible with the advent of new high-resolution non-destructive contact-less acquisition techniques for latent fingerprints. This requires reliable techniques for the automatic extraction of fingerprint features from latent and exemplar fingerprints for matching purposes using pattern recognition approaches. Therefore, we evaluate the NIST Biometric Image Software for the feature extraction and verification of contact-lessly acquired latent fingerprints to determine potential error rates. Our exemplary test setup includes 30 latent fingerprints from 5 people in two test sets that are acquired from different surfaces using a chromatic white light sensor. The first test set includes 20 fingerprints on two different surfaces. It is used to determine the feature extraction performance. The second test set includes one latent fingerprint on 10 different surfaces and an exemplar fingerprint to determine the verification performance. This utilized sensing technique does not require a physical or chemical visibility enhancement of the fingerprint residue, thus the original trace remains unaltered for further investigations. No particular feature extraction and verification techniques have been applied to such data, yet. Hence, we see the need for appropriate algorithms that are suitable to support forensic investigations.

  11. Determination of hydraulic properties of the Callovo-Oxfordian argillite at the bure site: Synthesis of the results obtained in deep boreholes using several in situ investigation techniques

    Science.gov (United States)

    Distinguin, Marc; Lavanchy, Jean-Marc

    -term monitoring sections). Borehole simulators were used to define a suitable flow model taking into account the complete pressure history of the borehole, and to derive best-guess estimates and uncertainty ranges for the hydraulic parameters. The sources of perturbations and the consistency of results are discussed in this paper. For instance, for a same interval tested through different techniques, an overestimation by one order of magnitude of the hydraulic conductivity due to a large overestimation of pore pressure during packer test was observed. In situ permeability estimations are also compared with those obtained from laboratory tests on core samples. Both short-term and long-term measurements provide values for the hydraulic conductivity at different scales with high consistency. This parameter is shown to be less than 2 × 10 -12 m/s. Pressures measurements from long-term monitoring are sufficiently accurate for determining formation hydraulic heads. A pressure profile in the argillite, derived from the extensive set of data currently available, shows an overpressure in the argillite 20-60 m above its surrounding formations. As a whole, the pressure data and derived hydraulic properties acquired from deep boreholes, offer a high degree of reliability and constitute a major contribution to the hydraulic characterisation of the low-permeable argillite formation. In 2006, this data will be complemented with measurements carried out in the Laboratory at 490 m depth, with the aim to characterize in greater depth the pressure profile of the argillite.

  12. Percutaneous thermoablation of lung metastases. Indication, techniques, first results, and imaging findings; Perkutane Laserablation von Lungenmetastasen. Indikation, technische Durchfuehrung, erste Ergebnisse und Bildbefunde

    Energy Technology Data Exchange (ETDEWEB)

    Weigel, C.; Schuchmann, S.; Kirsch, M.; Mensel, B.; Hosten, N. [Abteilung fuer Diagnostische und Interventionelle Radiologie, Klinikum der Ernst-Moritz-Arndt-Universtiaet Greifswald (Germany)

    2004-05-01

    Not unlike thermoablation of liver metastases, thermoablation of metastases to the lungs is gaining clinical interest. Radiofrequency ablation and laser-induced interstitial thermotherapy are both used clinically. Initially it was suspected that percutaneous treatment of lung metastases would result in a rate of pneumothoraces and tissue reactions which would not be clinically acceptable. However, this did not prove true. Fear of pneumothoraces however did lead to the desire for an applicator with a maximally reduced diameter. While clinical results are not yet available, technical success rates of laser-induced interstitial thermotherapy of lung metastases are promising. The percentage of pneumothoraces does not differ significantly from that seen in diagnostic procedures. Large metastases may be treated by simultaneous use of multiple applicators or by repositioning of an applicator (pullback technique). Surgical experience is still guiding us in deciding which primaries' metastases may be successfully treated percutaneously. The literature indicates that lung metastases from colorectal primaries are especially suited. Radiotherapy is only an alternative method in cases of lung metastases if they cause symptoms (such as pain because of thorax infiltration or difficulty in breathing because of bronchial lesion). Due to the risk of radiation-induced pneumonia general radiotherapy is not to be recommended. The possibility of stereotactic ray treatment is being considered, but because breathing shifts the metastases it is not yet feasible. Therefore, percutaneous thermoablation could be used as a minimally invasive, rather riskless therapeutic option for a relatively high percentage of inoperable lung metastases. (orig.) [German] Die Thermoablation von Lungenmetastasen ist dabei, sich aehnlich erfolgreich im klinischen Alltag zu etablieren wie die heute weit verbreitete Thermoablation von Lebermetastasen. Bei beiden Metastasierungsformen kommen die Radiofrequenz

  13. (25143) Itokawa: The Power of Radiometric Techniques for the Interpretation of Remote Thermal Observations in the Light of the Hayabusa Rendezvous Results

    CERN Document Server

    Müller, T G; Usui, F

    2014-01-01

    The near-Earth asteroid (25143) Itokawa was characterised in great detail by the Japanese Hayabusa mission. We revisited the available thermal observations in the light of the true asteroid properties with the goal to evaluate the possibilities and limitations of thermal model techniques. In total, we used 25 published ground-based mid-infrared photometric observations and 5 so far unpublished measurements from the Japanese infrared astronomical satellite AKARI in combination with improved H-G values. Our thermophysical model (TPM) approach allowed us to determine correctly the sense of rotation, to estimate the thermal inertia and to derive robust effective size and albedo values by only using a simple spherical shape model. A more complex shape model, derived from light-curve inversion techniques, improved the quality of the predictions considerably and made the interpretation of thermal light-curve possible. The radiometrically derived effective diameter value agrees within 2% of the true Itokawa size valu...

  14. Breathing adapted radiotherapy: final clinic results of the program for the support to costly innovating techniques (Stic) of 2003; La radiotherapie asservie a la respiration: resultats cliniques finaux du programme de Soutien aux techniques innovantes couteuses (Stic) de 2003

    Energy Technology Data Exchange (ETDEWEB)

    Giraud, P. [Universite Paris Descartes, 75 - Paris (France); Hopital europeen Georges-Pompidou, 75 - Paris (France); Giraud, P.; Morvan, E.; Djadi-Prat, J.; Rosenwald, J.C. [Institut Curie, 75 - Paris (France); Carrere, M.O. [GATE UMR CNRS 5824, 69 - Lyon (France); Centre Leon-Berard, 69 - Lyon (France)

    2010-10-15

    The authors report the comparison, from a clinic point of view, between breathing adapted conformational radiotherapy (BART) and conventional conformational radiotherapy, in the case of lung and breast cancers. The assessment comprised a clinic examination, a thoracic radiography, breathing functional tests, a thoracic scanography at different moments (3, 6, 12, 18 and 24 months), and dosimetric criteria for tumour target volumes and the different thoracic organs at risk. Data have been collected among more than six hundred patients. Breathing adapted techniques allow acute and late toxicity to be reduced, notably for the lung, heart and oesophagus during a lung irradiation. They are less interesting for mammary irradiation, but could be important for a radiotherapy of the left breast. Short communication

  15. MRI-Guided Intervention for Breast Lesions Using the Freehand Technique in a 3.0-T Closed-Bore MRI Scanner: Feasibility and Initial Results

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hye Young [Department of Radiology, Gyeongsang National University Hospital, Jinju 660-702 (Korea, Republic of); Kim, Sun Mi; Jang, Mijung; Yun, Bo La [Department of Radiology, Seoul National University Bundang Hospital, Seongnam 463-707 (Korea, Republic of); Kim, Sung-Won; Kang, Eunyoung [Department of Surgery, Seoul National University Bundang Hospital, Seongnam 463-707 (Korea, Republic of); Park, So Yeon [Department of Pathology, Seoul National University Bundang Hospital, Seongnam 463-707 (Korea, Republic of); Moon, Woo Kyung [Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul 110-744 (Korea, Republic of); Ko, Eun Sook [Department of Radiology, Samsung Medical Center, Seoul 135-710 (Korea, Republic of)

    2013-07-01

    To report the feasibility of magnetic resonance imaging (MRI)-guided intervention for diagnosing suspicious breast lesions detectable by MRI only, using the freehand technique with a 3.0-T closed-bore MRI scanner. Five women with 5 consecutive MRI-only breast lesions underwent MRI-guided intervention: 3 underwent MRI-guided needle localization and 2, MRI-guided vacuum-assisted biopsy. The interventions were performed in a 3.0-T closed-bore MRI system using a dedicated phased-array breast coil with the patients in the prone position; the freehand technique was used. Technical success and histopathologic outcome were analyzed. MRI showed that four lesions were masses (mean size, 11.5 mm; range, 7-18 mm); and 1, a nonmass-like enhancement (maximum diameter, 21 mm). The locations of the lesions with respect to the breast with index cancer were as follows: different quadrant, same breast - 3 cases; same quadrant, same breast - 1 case; and contralateral breast - 1 case. Histopathologic evaluation of the lesions treated with needle localization disclosed perilobular hemangioma, fibrocystic change, and fibroadenomatous change. The lesions treated with vacuum-assisted biopsy demonstrated a radial scar and atypical apocrine hyperplasia. Follow-up MRI after 2-7 months (mean, 4.6 months) confirmed complete lesion removal in all cases. MRI-guided intervention for breast lesions using the freehand technique with a 3.0-T closed-bore MRI scanner is feasible and accurate for diagnosing MRI-only lesions.

  16. CT-guided percutaneous radiofrequency ablation in osteoid osteoma. Re-assessments of results with optimized technique and possible pain patterns in mid-term follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Omlor, G.; Merle, C.; Lehner, B.; Ewerbeck, V. [Universitaetsklinik Heidelberg (Germany). Orthopaedische Universitaetsklinik; Rehnitz, C.; Weber, M.A. [Universitaetsklinik Heidelberg (Germany). Klinik fuer Diagnostische und Interventionelle Radiologie; Ludwig, K. [Klinikum Herford (Germany). Klinik fuer Diagnostische und Interventionelle Radiologie

    2012-04-15

    To re-assess radiofrequency ablation (RFA) of osteoid osteoma (OO) with an optimized technique and to evaluate patterns of post-interventional pain important for the detection of recurrence. 44 consecutive patients with OO treated with precise inclusion criteria by RFA were examined retrospectively. RFA was performed with an optimized technique. Technical success (TS), primary and secondary clinical success (PCS/SCS) and minor and major complications (MIC/MAC) were evaluated. Pain patterns defined as 'osteoid osteoma-specific pain' (OOSP) and 'unspecific pain' (UP), 'limitations in daily activity' (LDA) and 'patient satisfaction' (PS) were evaluated using a numeric rating scale (0 - 10; 0 = no pain, 0 = no limitation, 10 = fully satisfied). The pain intensity before and after RFA was compared. The mean follow-up time was 35 months (n = 40, range 2 - 60 months). TS was 100 % (n = 44), PCS 98 % (n = 44), and SCS 100 % (n = 40). MIC and MAC were 0 % (n = 44). OOSP was 0 after RFA in all 44 patients. UP was 0 in 24 of 40 patients (60 %), 1 in 11 patients (28 %) for up to 7 days and 1 - 4 in 5 patients (13 %) for 30 - 180 days. LDA was 0 in 39 of 40 patients (98 %), and 1 in 1 patient. PS was 10 in all patients. The pain after RFA was significantly less than before RFA (p < 0.0001). Using an optimized technique primary clinical success rates in the high nineties have to be expected. Unspecific pain of low intensity is not unusual after RFA and has to be distinguished from pain caused by recurrent disease. (orig.)

  17. An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result

    Directory of Open Access Journals (Sweden)

    Chi-Ta Lin

    2013-01-01

    Full Text Available An anthropomorphic phantom was used to investigate a treatment technique and analyze the dose distributions for helical irradiation of the total skin (HITS by helical tomotherapy (HT. Hypothetical bolus of thicknesses of 0, 10, and 15 mm was added around the phantom body to account for the dose homogeneity and setup uncertainty. A central core structure was assigned as a “complete block” to force the dose tangential delivery. HITS technique with prescribed dose (Dp of 36 Gy in 36 fractions was generated. The radiochromic EBT2 films were used for the dose measurements. The target region with 95.0% of the Dp received by more than 95% of the PTV was obtained. The calculated mean doses for the organs at risk (OARs were 4.69, 3.10, 3.20, and 2.94 Gy for the lung, heart, liver, and kidneys, respectively. The measurement doses on a phantom surface for a plan with 10 mm hypothetical bolus and bolus thicknesses of 0, 1, 2, and 3 mm are 89.5%, 111.4%, 116.9%, and 117.7% of Dp, respectively. HITS can provide an accurate and uniform treatment dose in the skin with limited doses to OARs and is safe to replace a total skin electron beam regimen.

  18. Proof-of-principle results for identifying the composition of dust particles and volcanic ash samples through the technique of photon activation analysis at the IAC

    Science.gov (United States)

    Mamtimin, Mayir; Cole, Philip L.; Segebade, Christian

    2013-04-01

    Instrumental analytical methods are preferable in studying sub-milligram quantities of airborne particulates collected in dust filters. The multi-step analytical procedure used in treating samples through chemical separation can be quite complicated. Further, due to the minute masses of the airborne particulates collected on filters, such chemical treatment can easily lead to significant levels of contamination. Radio-analytical techniques, and in particular, activation analysis methods offer a far cleaner alternative. Activation methods require minimal sample preparation and provide sufficient sensitivity for detecting the vast majority of the elements throughout the periodic table. In this paper, we will give a general overview of the technique of photon activation analysis. We will show that by activating dust particles with 10- to 30-MeV bremsstrahlung photons, we can ascertain their elemental composition. The samples are embedded in dust-collection filters and are irradiated "as is" by these photons. The radioactivity of the photonuclear reaction products is measured with appropriate spectrometers and the respective analytes are quantified using multi-component calibration materials. We shall provide specific examples of identifying the elemental components of airborne dust particles and volcanic ash by making use of bremsstrahlung photons from an electron linear accelerator at the Idaho Accelerator Center in Pocatello, Idaho.

  19. [Long-term results of mitral percutaneous valvuloplasty with Inoue technique. Seven-years experience at the Cardiology Hospital of the National Medical Center "Siglo XXI", IMSS].

    Science.gov (United States)

    Flores Flores, Jesús; Ledesma Velasco, Mariano; Palomo Villada, José Antonio; Montoya Guerrero, Silvestre; Estrada Gallegos, Joel; Astudillo Sandoval, Raúl; Abundes Velasco, Arturo; González Díaz, Belinda; Argüero Sánchez, Rubén; Farell Campa, Javier

    2006-01-01

    Since the last decade, percutaneous balloon mitral valvuloplasty with Inoue catheter is considered the treatment of choice for selected patients (mobile valve, no calcification and minimal subvalvular disease) with rheumatic mitral stenosis. We present the seven-year follow-up experience of 456 patients treated with this technique in the catheter laboratory of the Cardiology Hospital in National Medical Center SXXI. It is a retrospective, transversal and observational study performed with data obtained from January 1994 and December 2000, with a follow-up of 58.5 +/- 26.6 months (range 12-96 mean 22). We achieve an initial success of 82.8%, improvement of initial mitral valve area from 0.9 +/- 0.1 to 1.8 +/- 0.3 cm2, with a gain area from 88 to 106% (p 90%. From these patients, 93.1% remained in NYHA-II or -I functional class and the incidence of restenosis decreased.

  20. Results of the application of seismic-reflection and electromagnetic techniques for near-surface hydrogeologic and environmental investigations at Fort Bragg, North Carolina

    Science.gov (United States)

    Meyer, M.T.; Fine, J.M.

    1997-01-01

    As part of the U.S. Geological Survey's Resource Conservation and Recovery Act, Facilities Investigations at Fort Bragg, North Carolina, selected geophysical techniques were evaluated for their usefulness as assessment tools for determining subsurface geology, delineating the areal extent of potentially contaminated landfill sites, and locating buried objects and debris of potential environmental concern. Two shallow seismic-reflection techniques (compression and shear wave) and two electromagnetic techniques (ground-penetrating radar and terrain conductivity) were evaluated at several sites at the U.S. Army Base. The electromagnetic techniques also were tested for tolerance to cultural noise, such as nearby fences, vehicles, and power lines. For the terrain conductivity tests, two instruments were used--the EM31 and EM34, which have variable depths of exploration. The shallowest reflection event was 70 feet below land surface observed in common-depth point, stacked compression-wave data from 24- and 12-fold shallow-seismic-reflection surveys. Several reflection events consistent with clay-sand interfaces between 70 and 120 feet below land surface, along with basement-saprolite surfaces, were imaged in the 24-fold, common- depth-point stacked data. 12-fold, common-depth-point stacked data set contained considerably more noise than the 24-fold, common-depth-point data, due to reduced shot-to-receiver redundancy. Coherent stacked reflection events were not observed in the 24-fold, common-depth-point stacked shear-wave data because of the partial decoupling of the shear- wave generator from the ground. At one site, ground-penetrating radar effectively delineated a shallow, 2- to 5-foot thick sand unit bounded by thin (less than 1 foot) clay layers. The radar signal was completely attenuated where the overlying and underlying clay units thickened and the sand unit thinned. The pene- tration depth of the radar signal was less than 10 feet below land surface. A slight

  1. A New Rerouting Technique for the Extensor Pollicis Longus in Palliative Treatment for Wrist and Finger Extension Paralysis Resulting From Radial Nerve and C5C6C7 Root Injury.

    Science.gov (United States)

    Laravine, Jennifer; Cambon-Binder, Adeline; Belkheyar, Zoubir

    2016-03-01

    Wrist and finger extension paralysis is a consequence of an injury to the radial nerve or the C5C6C7 roots. Despite these 2 different levels of lesions, palliative treatment for this type of paralysis depends on the same tendon transfers. A large majority of the patients are able to compensate for a deficiency of the extension of the wrist and fingers. However, a deficiency in the opening of the first web space, which could be responsible for transfers to the abductor pollicis longus, the extensor pollicis brevis, and the extensor pollicis longus (EPL), frequently exists. The aim of this work was to evaluate the feasibility of a new EPL rerouting technique outside of Lister's tubercle. Another aim was to verify whether this technique allows a better opening of the thumb-index pinch in this type of paralysis. In the first part, we performed an anatomic study comparing the EPL rerouting technique and the frequently used technique for wrist and finger extension paralyses. In the second part, we present 2 clinical cases in which this new technique will be practiced. Preliminary results during this study favor the EPL rerouting technique. This is a simple and reproducible technique that allows for good opening of the first web space in the treatment of wrist and finger extension paralysis.

  2. The Number Density Evolution of Extreme Emission Line Galaxies in 3D-HST: Results from a Novel Automated Line Search Technique for Slitless Spectroscopy

    CERN Document Server

    Maseda, Michael V; Rix, Hans-Walter; Momcheva, Ivelina; Brammer, Gabriel B; Franx, Marijn; Lundgren, Britt F; Skelton, Rosalind E; Whitaker, Katherine E

    2016-01-01

    The multiplexing capability of slitless spectroscopy is a powerful asset in creating large spectroscopic datasets, but issues such as spectral confusion make the interpretation of the data challenging. Here we present a new method to search for emission lines in the slitless spectroscopic data from the 3D-HST survey utilizing the Wide-Field Camera 3 on board the Hubble Space Telescope. Using a novel statistical technique, we can detect compact (extended) emission lines at 90% completeness down to fluxes of 1.5 (3.0) times 10^{-17} erg/s/cm^2, close to the noise level of the grism exposures, for objects detected in the deep ancillary photometric data. Unlike previous methods, the Bayesian nature allows for probabilistic line identifications, namely redshift estimates, based on secondary emission line detections and/or photometric redshift priors. As a first application, we measure the comoving number density of Extreme Emission Line Galaxies (restframe [O III] 5007 equivalent widths in excess of 500 Angstroms)...

  3. Whole-organ perfusion of the pancreas using dynamic volume CT in patients with primary pancreas carcinoma: acquisition technique, post-processing and initial results

    Energy Technology Data Exchange (ETDEWEB)

    Kandel, Sonja; Kloeters, Christian; Meyer, Henning; Hein, Patrick; Rogalla, Patrik [Charite - Universitaetsmedizin Berlin, Department of Radiology, Campus Charite Mitte, Berlin (Germany); Hilbig, Andreas [Charite - University Medicine, Medical Clinic III - Hematology and Oncology, Campus Virchow Klinikum, Berlin (Germany)

    2009-11-15

    The purpose of this study was to evaluate a whole-organ perfusion protocol of the pancreas in patients with primary pancreas carcinoma and to analyse perfusion differences between normal and diseased pancreatic tissue. Thirty patients with primary pancreatic malignancy were imaged on a 320-slice CT unit. Twenty-nine cancers were histologically proven. CT data acquisition was started manually after contrast-material injection (8 ml/s, 350 mg iodine/ml) and dynamic density measurements in the right ventricle. After image registration, perfusion was determined with the gradient-relationship technique and volume regions-of-interest were defined for perfusion measurements. Contrast time-density curves and perfusion maps were generated. Statistical analysis was performed using the Kolmogorov-Smirnov test for analysis of normal distribution and Kruskal-Wallis test (nonparametric ANOVA) with Bonferroni correction for multiple stacked comparisons. In all 30 patients the entire pancreas was imaged, and registration could be completed in all cases. Perfusion of pancreatic carcinomas was significantly lower than of normal pancreatic tissue (P < 0.001) and could be visualized on colored perfusion maps. The 320-slice CT allows complete dynamic visualization of the pancreas and enables calculation of whole-organ perfusion maps. Perfusion imaging carries the potential to improve detection of pancreatic cancers due to the perfusion differences. (orig.)

  4. Investigation of a miRNA-Induced Gene Silencing Technique in Petunia Reveals Alterations in miR173 Precursor Processing and the Accumulation of Secondary siRNAs from Endogenous Genes.

    Directory of Open Access Journals (Sweden)

    Yao Han

    Full Text Available MIGS (miRNA-induced gene silencing is a straightforward and efficient gene silencing technique in Arabidopsis. It works by exploiting miR173 to trigger the production of phasiRNAs (phased small interfering RNAs. MIGS can be used in plant species other than Arabidopsis by co-expression of miR173 and target gene fragments fused to an upstream miR173 target site. However, the efficiency and technical mechanisms have not been thoroughly investigated in other plants. In this work, two vectors, pMIGS-chs and pMIGS-pds, were constructed and transformed into petunia plants. The transgenic plants showed CHS (chalcone synthase and PDS (phytoene desaturase gene-silencing phenotypes respectively, indicating that MIGS functions in petunia. MIGS-chs plants were used to investigate the mechanisms of this technique in petunia. Results of 5'- RACE showed that the miR173 target site was cleaved at the expected position and that endogenous CHS genes were cut at multiple positions. Small RNA deep sequencing analysis showed that the processing of Arabidopsis miR173 precursors in MIGS-chs transgenic petunia plants did not occur in exactly the same way as in Arabidopsis, suggesting differences in the machinery of miRNA processing between plant species. Small RNAs in-phase with the miR173 cleavage register were produced immediately downstream from the cleavage site and out-of-phase small RNAs were accumulated at relatively high levels from processing cycle 5 onwards. Secondary siRNAs were generated from multiple sites of endogenous CHS-A and CHS-J genes, indicating that miR173 cleavage induced siRNAs have the same ability to initiate siRNA transitivity as the siRNAs functioning in co-suppression and hpRNA silencing. On account of the simplicity of vector construction and the transitive amplification of signals from endogenous transcripts, MIGS is a good alternative gene silencing method for plants, especially for silencing a cluster of homologous genes with redundant

  5. Theory-Based Interventions Combining Mental Simulation and Planning Techniques to Improve Physical Activity: Null Results from Two Randomized Controlled Trials.

    Science.gov (United States)

    Meslot, Carine; Gauchet, Aurélie; Allenet, Benoît; François, Olivier; Hagger, Martin S

    2016-01-01

    Interventions to assist individuals in initiating and maintaining regular participation in physical activity are not always effective. Psychological and behavioral theories advocate the importance of both motivation and volition in interventions to change health behavior. Interventions adopting self-regulation strategies that foster motivational and volitional components may, therefore, have utility in promoting regular physical activity participation. We tested the efficacy of an intervention adopting motivational (mental simulation) and volitional (implementation intentions) components to promote a regular physical activity in two studies. Study 1 adopted a cluster randomized design in which participants (n = 92) were allocated to one of three conditions: mental simulation plus implementation intention, implementation intention only, or control. Study 2 adopted a 2 (mental simulation vs. no mental simulation) × 2 (implementation intention vs. no implementation intention) randomized controlled design in which fitness center attendees (n = 184) were randomly allocated one of four conditions: mental simulation only, implementation intention only, combined, or control. Physical activity behavior was measured by self-report (Study 1) or fitness center attendance (Study 2) at 4- (Studies 1 and 2) and 19- (Study 2 only) week follow-up periods. Findings revealed no statistically significant main or interactive effects of the mental simulation and implementation intention conditions on physical activity outcomes in either study. Findings are in contrast to previous research which has found pervasive effects for both intervention strategies. Findings are discussed in light of study limitations including the relatively small sample sizes, particularly for Study 1, deviations in the operationalization of the intervention components from previous research and the lack of a prompt for a goal intention. Future research should focus on ensuring uniformity in the format of the

  6. Theory-Based Interventions Combining Mental Simulation and Planning Techniques to Improve Physical Activity: Null Results from Two Randomized Controlled Trials

    Science.gov (United States)

    Meslot, Carine; Gauchet, Aurélie; Allenet, Benoît; François, Olivier; Hagger, Martin S.

    2016-01-01

    Interventions to assist individuals in initiating and maintaining regular participation in physical activity are not always effective. Psychological and behavioral theories advocate the importance of both motivation and volition in interventions to change health behavior. Interventions adopting self-regulation strategies that foster motivational and volitional components may, therefore, have utility in promoting regular physical activity participation. We tested the efficacy of an intervention adopting motivational (mental simulation) and volitional (implementation intentions) components to promote a regular physical activity in two studies. Study 1 adopted a cluster randomized design in which participants (n = 92) were allocated to one of three conditions: mental simulation plus implementation intention, implementation intention only, or control. Study 2 adopted a 2 (mental simulation vs. no mental simulation) × 2 (implementation intention vs. no implementation intention) randomized controlled design in which fitness center attendees (n = 184) were randomly allocated one of four conditions: mental simulation only, implementation intention only, combined, or control. Physical activity behavior was measured by self-report (Study 1) or fitness center attendance (Study 2) at 4- (Studies 1 and 2) and 19- (Study 2 only) week follow-up periods. Findings revealed no statistically significant main or interactive effects of the mental simulation and implementation intention conditions on physical activity outcomes in either study. Findings are in contrast to previous research which has found pervasive effects for both intervention strategies. Findings are discussed in light of study limitations including the relatively small sample sizes, particularly for Study 1, deviations in the operationalization of the intervention components from previous research and the lack of a prompt for a goal intention. Future research should focus on ensuring uniformity in the format of the

  7. Phase I report : Evaluating marsh and upland habitat management techniques and their resulting effects on wildlife in the San Luis Valley, Colorado

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is the result of a lawsuit that Monte Vista National Wildlife Refuge and other refuges were involved in focusing on the compatibility issue related to...

  8. Dethrombosis of the lower extremity arteries using the power-pulse spray technique in patients with recent onset thrombotic occlusions: results of the DETHROMBOSIS Registry.

    Science.gov (United States)

    Shammas, Nicolas W; Dippel, Eric J; Shammas, Gail; Gayton, Laura; Coiner, Denise; Jerin, Mike

    2008-10-01

    partial or complete thrombus resolution in about two thirds of the patients treated. The overall safety outcome was favorable, but large studies are needed to test the effectiveness of the P-PS/RT technique prior to routine use.

  9. The outcome of a bilateral leg amputation according to Syme;s technique as a result of posttraumatic complications: a case report.

    Science.gov (United States)

    Wasiak, Krzysztof; Paczkowski, Paweł; Danis, Dariusz

    2005-04-30

    Background. The purpose of this article is to present the problems encountered in treatment and rehabilitation, including prosthesis fitting, in the case of a 17-year-old female patient who underwent a bilateral leg amputation using Syme's method. Case history. The patient incurred crushing injuries of both feet and the knee joints, resulting from a severe multi-organ injury. As a result of post-traumatic changes and deformations of the feet, including algodystrophic changes, amputation proved to be the only procedure that would restore the patient locomotive capacity. Outcome. As a result of the treatment applied, the patient regained the ability to move about, while the primary limitation on her locomotive abilities turned out to be the status of her knee joints, which had been severely damaged in the accident.

  10. Surgical treatment of moyamoya disease: operative technique for encephalo-duro-arterio-myo-synangiosis, its follow-up, clinical results, and angiograms.

    Science.gov (United States)

    Kinugasa, K; Mandai, S; Kamata, I; Sugiu, K; Ohmoto, T

    1993-04-01

    Moyamoya syndrome is defined as the development of collateral anastomosis pathways at the base of the brain, associated with chronic progressive stenosis of the carotid fork. Both reconstructive vascular surgery and conservative strategies are used to treat this syndrome, but the latter cannot prevent the disease from progressing. We describe the procedure of encephalo-duro-arterio-myo-synangiosis (EDAMS), and report the results in 17 patients (28 sides) who underwent EDAMS. The clinical symptoms of moyamoya disease include transient ischemic attacks, reversible ischemic neurological deficits, stroke, seizures, Gerstmann's syndrome, involuntary movements, or mental retardation resulting from the lack of cerebral blood flow. The clinical results of EDAMS were poor in one patient, fair in two, good in five, excellent in eight, and fair on one side and excellent on the other side in one patient. Postoperative angiograms showed widespread collateral circulation on the ischemic brain surface in patients undergoing EDAMS.

  11. Behavioral Risk Profile of Men Who Have Sex with Men in Beijing, China: Results from a Cross-sectional Survey with Randomized Response Techniques

    Directory of Open Access Journals (Sweden)

    Guo-Zhu Geng

    2016-01-01

    Conclusions: Our study employed RRTs in a survey containing questions on sexual behavior among MSM, and the results showed that RRT might be a useful tool to obtain truthful feedback on sensitive information such as sexual behavior from the respondents, especially in traditional Chinese cultural settings.

  12. Lipidomics and H218O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio embryos

    Directory of Open Access Journals (Sweden)

    Melissa Q. McDougall

    2016-08-01

    Full Text Available We hypothesized that vitamin E (α-tocopherol is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6, the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio defined diets without (E− or with added α-tocopherol (E+, 500 mg RRR-α-tocopheryl acetate/kg diet for a minimum of 80 days, and then spawned them to obtain E− and E+ embryos. The E− compared with E+ embryos were 82% less responsive (p<0.01 to a light/dark stimulus at 96 h post-fertilization (hpf, demonstrating impaired locomotor behavior, even in the absence of gross morphological defects. Evaluation of phospholipid (PL and lysophospholipid (lyso-PL composition using untargeted lipidomics in E− compared with E+ embryos at 24, 48, 72, and 120 hpf showed that four PLs and three lyso-PLs containing docosahexaenoic acid (DHA, including lysophosphatidylcholine (LPC 22:6, required for transport of DHA into the brain, p<0.001, were at lower concentrations in E− at all time-points. Additionally, H218O labeling experiments revealed enhanced turnover of LPC 22:6 (p<0.001 and three other DHA-containing PLs in the E− compared with the E+ embryos, suggesting that increased membrane remodeling is a result of PL depletion. Together, these data indicate that α-tocopherol deficiency in the zebrafish embryo causes the specific depletion and increased turnover of DHA-containing PL and lyso-PLs, which may compromise DHA delivery to the brain and thereby contribute to the functional impairments observed in E− embryos.

  13. Results on the electrochromic and photocatalytic properties of vanadium doped tungsten oxide thin films prepared by reactive dc magnetron sputtering technique

    Science.gov (United States)

    Muthu Karuppasamy, K.; Subrahmanyam, A.

    2008-02-01

    In this investigation, vanadium doped tungsten oxide (V : WO3) thin films are prepared at room temperature by reactive dc magnetron sputtering employing a tungsten-vanadium 'inlay' target. In comparison with pure sputtered tungsten oxide thin films, 11% vanadium doping is observed to decrease the optical band gap, enhance the colour neutral property, decrease the coloration efficiency (from 121 to 13 cm2 C-1), increase the surface work function (4.68-4.83 eV) and significantly enhance the photocatalytic efficiency in WO3 thin films. These observations suggest that (i) vanadium creates defect levels that are responsible for optical band gap reduction, (ii) multivalent vanadium bonding with terminal oxygen in the WO3 lattice gives rise to localized covalent bonds and thus results in an increase in the work function, and (iii) a suitable work function of V : WO3 with ITO results in an enhancement of the photocatalytic activity. These results on electrochromic and photocatalytic properties of V : WO3 thin films show good promise in the low maintenance window application.

  14. Results on the electrochromic and photocatalytic properties of vanadium doped tungsten oxide thin films prepared by reactive dc magnetron sputtering technique

    Energy Technology Data Exchange (ETDEWEB)

    Karuppasamy, K Muthu; Subrahmanyam, A [Semiconductor Laboratory, Department of Physics, Indian Institute of Technology Madras, Chennai 600036 (India)

    2008-02-07

    In this investigation, vanadium doped tungsten oxide (V : WO{sub 3}) thin films are prepared at room temperature by reactive dc magnetron sputtering employing a tungsten-vanadium 'inlay' target. In comparison with pure sputtered tungsten oxide thin films, 11% vanadium doping is observed to decrease the optical band gap, enhance the colour neutral property, decrease the coloration efficiency (from 121 to 13 cm{sup 2} C{sup -1}), increase the surface work function (4.68-4.83 eV) and significantly enhance the photocatalytic efficiency in WO{sub 3} thin films. These observations suggest that (i) vanadium creates defect levels that are responsible for optical band gap reduction, (ii) multivalent vanadium bonding with terminal oxygen in the WO{sub 3} lattice gives rise to localized covalent bonds and thus results in an increase in the work function, and (iii) a suitable work function of V : WO{sub 3} with ITO results in an enhancement of the photocatalytic activity. These results on electrochromic and photocatalytic properties of V : WO{sub 3} thin films show good promise in the low maintenance window application.

  15. Experimental techniques; Techniques experimentales

    Energy Technology Data Exchange (ETDEWEB)

    Roussel-Chomaz, P. [GANIL CNRS/IN2P3, CEA/DSM, 14 - Caen (France)

    2007-07-01

    This lecture presents the experimental techniques, developed in the last 10 or 15 years, in order to perform a new class of experiments with exotic nuclei, where the reactions induced by these nuclei allow to get information on their structure. A brief review of the secondary beams production methods will be given, with some examples of facilities in operation or under project. The important developments performed recently on cryogenic targets will be presented. The different detection systems will be reviewed, both the beam detectors before the targets, and the many kind of detectors necessary to detect all outgoing particles after the reaction: magnetic spectrometer for the heavy fragment, detection systems for the target recoil nucleus, {gamma} detectors. Finally, several typical examples of experiments will be detailed, in order to illustrate the use of each detector either alone, or in coincidence with others. (author)

  16. Development of a Technique and Method of Testing Aircraft Models with Turboprop Engine Simulators in a Small-scale Wind Tunnel - Results of Tests

    Directory of Open Access Journals (Sweden)

    A. V. Petrov

    2004-01-01

    Full Text Available This report presents the results of experimental investigations into the interaction between the propellers (Ps and the airframe of a twin-engine, twin-boom light transport aircraft with a Π-shaped tail. An analysis was performed of the forces and moments acting on the aircraft with rotating Ps. The main features of the methodology for windtunnel testing of an aircraft model with running Ps in TsAGI’s T-102 wind tunnel are outlined.The effect of 6-blade Ps slipstreams on the longitudinal and lateral aerodynamic characteristics as well as the effectiveness of the control surfaces was studied on the aircraft model in cruise and takeoff/landing configurations. The tests were conducted at flow velocities of V∞ = 20 to 50 m/s in the ranges of angles of attack α =  -6 to 20 deg, sideslip angles of β = -16 to 16 deg and blade loading coefficient of B 0 to 2.8. For the aircraft of unusual layout studied, an increase in blowing intensity is shown to result in decreasing longitudinal static stability and significant asymmetry of the directional stability characteristics associated with the interaction between the Ps slipstreams of the same (left-hand rotation and the empennage.

  17. Superficial temporal artery-middle cerebral artery bypass combined with encephalo-duro-myo-synangiosis in treating moyamoya disease: surgical techniques, indications and midterm follow-up results

    Institute of Scientific and Technical Information of China (English)

    XU Bin; SONG Dong-lei; MAO Ying; GU Yu-xiang; XU Hong; LIAO Yu-jun; LIU Chuang-hong; ZHOU Liang-fu

    2012-01-01

    Background Surgical interventions for moyamoya disease include direct and indirect revascularizations.This study aimed to evaluate the therapeutic effect of superficial temporal artery-middle cerebral artery bypass combined with an indirect revascularization procedure,encephalo-duro-myo-synangiosis,in the treatment of moyamoya disease.Methods From October 2005 to November 2009,we performed this combined revascularization procedure in 111 patients with different types and stages of moyamoya disease.The superficial temporal artery,middle meningeal artery and the deep temporal artery were evaluated for individualized surgical planning in these cases.The integrity of the deep temporal artery and the middle meningeal artery network,and the pre-existing spontaneous anastomoses of the distal branches of the external carotid artery with the cortical arteries were well preserved.The mean follow-up time was 72.5 months,all clinical and radiological data were retrospectively reviewed.Results A total of 198 stomas were performed in 122 hemispheres,all remaining patent until the last follow-up.The encephalo-duro-myo-synangiosis resulted in extensive anastomoses of the deep temporal artery (100%),the middle meningeal artery (90.9%),and the sphenopalatine artery (39.8%) with the cortical arteries,respectitvely.The superficial temporal artery,deep temporal artery,and the middle meningeal artery were significantly thickened in 88 patients as determined by digital subtraction angiography at follow-up.The relative cerebral blood flow increased significantly within one week after the operation.At 6 months post the operation,the relative cerebral blood flow was further increased by 15.5% from the gradual formation of anastomoses as a result of indirect revascularization.Transient ischemic attacks were effectively reduced or totally arrested.The neurological deficits significantly improved in 37 patients,with the National Institutes of Health Stroke Scale scores lowered by 2

  18. Restoration of prehension with the double free muscle technique following complete avulsion of the brachial plexus. Indications and long-term results.

    Science.gov (United States)

    Doi, K; Muramatsu, K; Hattori, Y; Otsuka, K; Tan, S H; Nanda, V; Watanabe, M

    2000-05-01

    Recent interest in reconstruction of the upper limb following brachial plexus injuries has focused on the restoration of prehension following complete avulsion of the brachial plexus. Double free muscle transfer was performed in patients who had complete avulsion of the brachial plexus. After initial exploration of the brachial plexus and (if possible) repair of the fifth cervical nerve root, the first free muscle, used to restore elbow flexion and finger extension, is transferred and reinnervated by the spinal accessory nerve. The second free muscle, transferred to restore finger flexion, is reinnervated by the fifth and sixth intercostal nerves. The motor branch of the triceps brachii is reinnervated by the third and fourth intercostal nerves to restore elbow extension. Hand sensibility is restored by suturing of the sensory rami of the intercostal nerves to the median nerve or the ulnar nerve component of the medial cord. Secondary reconstructive procedures, such as arthrodesis of the carpometacarpal joint of the thumb, shoulder arthrodesis, and tenolysis of the transferred muscle and the distal tendons, may be required to improve the functional outcome. The early results were evaluated in thirty-two patients who had had reconstruction with use of the double free muscle procedure. Twenty-six of these patients were followed for at least twenty-four months (mean duration, thirty-nine months) after the second free muscle transfer, and they were assessed with regard to the long-term outcome as well. Satisfactory (excellent or good) elbow flexion was restored in twenty-five (96 percent) of the twenty-six patients and satisfactory prehension (more than 30 degrees of total active motion of the fingers), in seventeen (65 percent). Fourteen patients (54 percent) could position the hand in space, negating simultaneous flexion of the elbow, while moving the fingers at least 30 degrees and could use the reconstructed hand for activities requiring the use of two hands, such

  19. PRELIMINARY RESULTS OF ATMOSPHERIC DEPOSITION OF MAJOR AND TRACE ELEMENTS IN THE GREATER AND LESSER CAUCASUS MOUNTAINS STUDIED BY THE MOSS TECHNIQUE AND NEUTRON ACTIVATION ANALYSIS

    Directory of Open Access Journals (Sweden)

    S. Shetekauri

    2015-05-01

    Full Text Available The method of moss biomonitoring of atmospheric deposition of trace elements was applied for the first time in the western Caucasus Mountains to assess the environmental situation in this region. The sixteen moss samples have been collected in 2014 summer growth period along altitudinal gradients in the range of altitudes from 600 m to 2665 m. Concentrations of Na, Mg, Al, Cl, K, Ca, Ti, V, Mn, Fe, Zn, As, Br, Rb, Mo, Cd, I, Sb, Ba, La, Sm, W, Au, and U determined by neutron activation analysis in the moss samples are reported. A comparison with the data for moss collected in Norway (pristine area was carried out.  Multivariate statistical analysis of the results was used for assessment pollution sources in the studied part of the Caucasus. The increase in concentrations of most of elements with rising altitude due to gradually disappearing vegetation cover and wind erosion of soil was observed. A comparison with the available data for moss collected in the Alps at the same altitude (~ 2500 m was performed.

  20. 3D cone-beam CT guidance, a novel technique in renal biopsy - results in 41 patients with suspected renal masses

    Energy Technology Data Exchange (ETDEWEB)

    Braak, Sicco J.; Heesewijk, Johannes P.M. van; Strijen, Marco J.L. van [St Antonius Hospital, Department of Radiology, PO Box 2500, Nieuwegein (Netherlands); Melick, Harm H.E. van; Onaca, Mircea G. [St Antonius Hospital, Department of Urology, Nieuwegein (Netherlands)

    2012-11-15

    To determine whether 3D cone-beam computed tomography (CBCT) guidance allows safe and accurate biopsy of suspected small renal masses (SRM), especially in hard-to-reach anatomical locations. CBCT guidance was used to perform 41 stereotactic biopsy procedures of lesions that were inaccessible for ultrasound guidance or CT guidance. In CBCT guidance, a 3D-volume data set is acquired by rotating a C-arm flat-panel detector angiosystem around the patient. In the data set, a needle trajectory is determined and, after co-registration, a fusion image is created from fluoroscopy and a slice from the data set, enabling the needle to be positioned in real time. Of the 41 lesions, 22 were malignant, 17 were benign, and 2 were nondiagnostic. The two nondiagnostic lesions proved to be renal cell carcinoma. There was no growth during follow-up imaging of the benign lesions (mean 29 months). This resulted in a sensitivity, specificity, PPV, NPV, and accuracy of 91.7, 100, 100, 89.5, and 95.1%, respectively. Mean dose-area product value was 44.0 Gy.cm{sup 2} (range 16.5-126.5). There was one minor bleeding complication. With CBCT guidance, safe and accurate biopsy of a suspected SRM is feasible, especially in hard-to-reach locations of the kidney. (orig.)

  1. 卫生应急关键技术筛选框架设计与结果分析*%Research on the Framework Design of Selecting Key Techniques of Public Health Emergency Response and the Analysis of Results

    Institute of Scientific and Technical Information of China (English)

    吴群红; 胥娇; 郝艳华; 宁宁

    2013-01-01

      目的:探讨卫生应急关键技术概念、内涵、筛选框架、原则及方法。方法:运用头脑风暴法及专题讨论法,构建卫生应急关键技术筛选框架,通过议题小组法明确卫生应急关键技术筛选标准,运用德尔菲法筛选关键技术。结果:设计了基于突发公共卫生事件分类、生命周期处置流程、技术层次、技术范畴的四维卫生应急关键技术研究框架,通过平均算术法和秩和法筛选了包括一级、二级技术在内的9大类共59项基层迫切需要的卫生应急关键技术集。结论:卫生应急关键技术的框架设计和筛选方法具有科学性、实用性和可操作性,研究可为今后进一步遴选、研究和开发关键技术提供概念框架和工具指南。%Objective: To explore the concept, connotation, selection framework, principles and methods of selecting the key techniques of health emergency. Methods: By using method of brainstorming and focused group discussion, the framework of selecting the key techniques of public health emergency was constructed, the criteria for key techniques selection was developed through nominal group discussion method;then a set of key techniques were identified through nominal group discussion method. Results:The framework for selecting key techniques was designed based on four dimensions: the classification of emergency events, life cycle of emergency response, level of techniques and technique category; based on the results of arithmetic average and rank sum method, 59 key techniques out of 9 types were selected. Conclusion: Selection framework and method of public health emergency key techniques are scientific, feasible, and applicable, which provide the conceptual framework and guideline for further research.

  2. Estapedotomia totalmente endoscópica: técnica e resultados preliminares Fully endoscopic stapes surgery (stapedotomy: technique and preliminary results

    Directory of Open Access Journals (Sweden)

    João Flávio Nogueira Júnior

    2011-12-01

    visualization of important structures. b To show initial results, discuss possible advantages and disadvantages of this instrument. METHODS: 15 patients with otosclerosis were selected to undergo stapedotomies in 2010. The data and surgery videos were analyzed retrospectively (study case series. The anatomical conditions of the oval window niche and surgical steps were described and used to assess possible benefits of such procedures. RESULTS: The surgeries were performed with endoscopes only and all relevant anatomical structures were visualized without difficulty. No complications were observed and 14 of the 15 patients reported improvement of their hearing, confirmed by postoperative audiological tests. CONCLUSION: Totally endoscopic stapes surgeries are technically feasible, safe and promising. In this small series, the main advantages were: virtually no trauma to the chorda tympani nerve and excellent vision. The disadvantages were the lack of stereoscopic vision, having to work with one hand only and the learning curve.

  3. The result analysis by A-Frame technique in coating failure detection; Analise dos resultados do uso da tecnica A-Frame na localizacao de falhas no revestimento

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Fabio Amarante; Leite, Daniele C.F. [PETROBRAS, Rio de Janeiro, RJ (Brazil); Oliver, Joao Hipolito L. [TRANSPETRO - PETROBRAS Transportes, Rio de Janeiro, RJ (Brazil)

    2005-07-01

    This paper presents the method used to helps the on land pipeline integrity management, focusing on external corrosion control. The method is achieved by gathering together the data from an Over The Line Survey (OLS) and an In Line Inspection (ILI). As the corrosion occurs at a coating fault in a non-effective cathodic protection (cp) area, both coating and metal loss inspection data were employed in this method. The OLS is applied to pinpoint and graduate the coating faults in underground pipeline by using the Coating Attenuation / A-Frame (ACVG - Alternate Current Voltage Gradient) technic. The ILI is applied to measure the external metal loss (corrosion) by running a smart PIG tool. In some pipelines a huge number of coating fault can be found, but it doesn't mean that all of them must be repaired, so it is a need to identify the critical coating fault, so that the number of digging for coating repair can be drastically reduced. In the other way, as the smart PIG can provide data of corrosion in the pipe, the coating fault on a corroded area can be considered as a critical one. Together, those data may point the spot where the cathodic protection was not effective and the coating failure resulted in corrosion on the pipe. This method has been a helpful criterion to identify critical coating faults and reduce the overall repair cost, it can be also used to indirect evaluate the performance of cp system, since no corrosion indication on a coating fault area can be assumed that the CP is effective. (author)

  4. Serum 3,3'-L-diiodothyronine, a direct radioimmunoassay in human serum: method and clinical results. [/sup 125/I tracer technique

    Energy Technology Data Exchange (ETDEWEB)

    Burger, A.; Sakoloff, C.

    1977-09-01

    A specific radioimmunoassay for 3,3'-diiodothyronine (T/sub 2/) is described which is capable of detecting as little as 1.3 ng/dl. The antiserum recognizes mainly T/sub 2/; biliary conjugates of T/sub 2/ bind slightly to the antibody. The intraassay and interassay coefficients of variation were, respectively, 5.7% and 13.1%. T/sub 2/ was detected in the serum of hypothyroid patients treated with triiodothyronine (T/sub 3/) and in euthyroid subjects treated with reverse triiodothyronine (rT/sub 3/). These results suggest that both T/sub 3/ and rT/sub 3/ are deiodinated to T/sub 2/. Serum concentrations of T/sub 2/ in normal subjects decreased with age. Between 20 and 40 years the mean concentration was 4.3 +- 2.0 ng/dl (2 SD), between 41 and 60 years it varied from 1.9 to 5.8 ng/dl (3.8 +- 0.3 ng/dl, SE) and in elderly subjects have 60 years concentrations varied from unmeasurable to 4 ng/dl (2.9 +- 0.4 ng/dl, SE). Low serum T/sub 2/ concentrations were found in anorexia nervosa (2.5 +- 0.3 ng/dl, SE). In hypothyroidism the serum concentrations were low or unmeasurable. As most of the hypothyroid subjects were elderly their serum T/sub 2/ concentrations overlapped with the low values found in the elderly euthyroid subjects. In classical hyperthyroidism serum T/sub 2/ concentrations were greatly increased (3.3 to 31 ng/dl (11.8 +- 2.7 ng/dl, SE) but in ''T/sub 3/ toxicosis'' the concentrations were only modestly increased (2.4 to 8.8 ng/dl, 5.2 +- 0.8 ng/dl, SE).

  5. Noninvasive assessment of coronary artery disease by multislice spiral computed tomography using a new retrospectively ECG-gated image reconstruction technique. Comparison with angiographic results

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Yuichi; Matsumoto, Naoya; Kato, Masahiko [Nihon Univ., Tokyo (Japan). Surugadai Hospital] [and others

    2003-04-01

    The present study was designed to investigate the accuracy of multislice spiral computed tomography (MSCT) in detecting coronary artery disease, compared with coronary angiography (CAG), using a new retrospectively ECG-gated reconstruction method that reduced cardiac motion artifact. The study group comprised 54 consecutive patients undergoing MSCT and CAG. MSCT was performed using a SOMATOM Volume Zoom (4-detector-row, Siemens, Germany) with slice thickness 1.0 mm, pitch 1.5 (table feed: 1.5 mm per rotation) and gantry rotation time 500 ms. Metoprolol (20-60 mg) was administered orally prior to MSCT imaging. ECG-gated image reconstruction was performed with the reconstruction window (250 ms) positioned immediately before atrial contraction in order to reduce the cardiac motion artifact caused by the abrupt diastolic ventricular movement occurring during the rapid filling and atrial contraction periods. Following inspection of the volume rendering images, multiplanar reconstruction images and axial images of the left main coronary artery (LMCA), left anterior descending artery (LAD), left circumflex artery (LCx) and right coronary artery (RCA) were obtained and evaluated for luminal narrowing. The results were compared with those obtained by CAG. Of 216 coronary arteries, 206 (95.4%) were assessable; 10 arteries were excluded from the analysis because of severe calcification (n=4), stents (n=3) or insufficient contrast enhancement (n=3). The sensitivity to detect coronary stenoses {>=}50% was 93.5% and the specificity to define luminal narrowing <50% was 97.2%. The positive predictive value and the negative predictive value were 93.5% and 97.2%, respectively. The sensitivity was still satisfactory (80.6%) even when non-assessable arteries were included in the analysis. The new retrospectively ECG-gated reconstruction method for MSCT has excellent diagnostic accuracy in detecting significant coronary artery stenoses. (author)

  6. A Technique for Determining Relaxation Times by Free-Flight Tests of Low-Fineness-Ratio Cones; with Experimental Results for Air at Equilibrium Temperatures up to 3440 K

    Science.gov (United States)

    Stephenson, Jack D.

    1960-01-01

    This report describes a technique which combines theory and experiments for determining relaxation times in gases. The technique is based on the measurement of shapes of the bow shock waves of low-fineness-ratio cones fired from high-velocity guns. The theory presented in the report provides a means by which shadowgraph data showing the bow waves can be analyzed so as to furnish effective relaxation times. Relaxation times in air were obtained by this technique and the results have been compared with values estimated from shock tube measurements in pure oxygen and nitrogen. The tests were made at velocities ranging from 4600 to 12,000 feet per second corresponding to equilibrium temperatures from 35900 R (19900 K) to 6200 R (34400 K), under which conditions, at all but the highest temperatures, the effective relaxation times were determined primarily by the relaxation time for oxygen and nitrogen vibrations.

  7. Can we derive an 'exchange rate' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU technique

    Directory of Open Access Journals (Sweden)

    Segal Leonie

    2009-04-01

    Full Text Available Abstract Background Stroke-specific outcome measures and descriptive measures of health-related quality of life (HRQoL are unsuitable for informing decision-makers of the broader consequences of increasing or decreasing funding for stroke interventions. The quality-adjusted life year (QALY provides a common metric for comparing interventions over multiple dimensions of HRQoL and mortality differentials. There are, however, many circumstances when – because of timing, lack of foresight or cost considerations – only stroke-specific or descriptive measures of health status are available and some indirect means of obtaining QALY-weights becomes necessary. In such circumstances, the use of regression-based transformations or mappings can circumvent the failure to elicit QALY-weights by allowing predicted weights to proxy for observed weights. This regression-based approach has been dubbed 'Transfer to Utility' (TTU regression. The purpose of the present study is to demonstrate the feasibility and value of TTU regression in stroke by deriving transformations or mappings from stroke-specific and generic but descriptive measures of health status to a generic preference-based measure of HRQoL in a sample of Australians with a diagnosis of acute stroke. Findings will quantify the additional error associated with the use of condition-specific to generic transformations in stroke. Methods We used TTU regression to derive empirical transformations from three commonly used descriptive measures of health status for stroke (NIHSS, Barthel and SF-36 to a preference-based measure (AQoL suitable for attaching QALY-weights to stroke disease states; based on 2570 observations drawn from a sample of 859 patients with stroke. Results Transformations from the SF-36 to the AQoL explained up to 71.5% of variation in observed AQoL scores. Differences between mean predicted and mean observed AQoL scores from the 'severity-specific' item- and subscale-based SF-36

  8. Técnica e resultados da endarterectomia de artéria coronária Technique and results of coronary endarterectomy

    Directory of Open Access Journals (Sweden)

    Pedro R Salerno

    1994-09-01

    que a endarterectomia é um procedimento que, utilizado criteriosamente, possibilita uma RM completa e com resultados consistentes.The surgical approach to coronary artery disease has improved a lot during the past two decades. With the widespread use of balloon angioplasty, a growing percentage of surgical patients, have complex coronary pathology. In properly selected patients, coronary endarterectomy has been a valuable adjunt to bypass techiniques by removing obstructing lesions and preparing the distal artery for bypass grafting. Over a 5 years period (1988 to 1993, 2781 patients underwent surgical revascularization at our Instituition (Hospital do Coração. Coronary artery bypass combined with coronary endarterectomy was done in 110 patients. There were 99 men (90% and 11 women, mean age 58.9 years. For comparation patients were placed into two groups: Group A, patients undergoing endarterectomy to one artery, 104 patients - 94.5%. Group B, patients with more than one endarterectomy - 6 patients 5.4%. Perioperative myocardial infarction envolving the area supplied by the endarterectomized artery occurred in 6.3%, (7 patients. In 3 (2.7% the infarction was not related with the endarterectomized artery. Complications during the post-operative period were: arrhythmia in 26 patients (23.6%, return to the operation room for control of bleeding in 12 (10.9%, acute renal failure in 10 (9%, and low cardiac output in 4 (3.6% patients. Operative mortality rate was 4.5% (5/110, due to low cardiac output and multiple organs failure; 4 (3.8% patients belonged to Group A and 1 to Group B (16.6%. This study demostrates that multiple bypass grafting and adjunt coronary endarterectomy, can yeld good clinical results in patients with difuse coronary artery disease, many of whom would otherwise be inoperable.

  9. Techniques and results for open hip preservation

    Directory of Open Access Journals (Sweden)

    David eLevy

    2015-12-01

    Full Text Available While hip arthroscopy grows in popularity, there are still many circumstances under which open hip preservation is most appropriately indicated. This article specifically reviews open hip preservation procedures for a variety of hip conditions. Femoral acetabular impingement may be corrected using an open surgical hip dislocation. Acetabular dysplasia may be corrected using a periacetabular osteotomy. Acetabular protrusio may require surgical hip dislocation with rim trimming and a possible valgus intertrochanteric osteotomy. Legg-Calve ́-Perthes disease produces complex deformities that may be better served with osteotomies of the proximal femur and/ or acetabulum. Chronic slipped capital femoral epiphysis (SCFE may also benefit from a surgical hip dislocation and/or proximal femoral osteotomy.

  10. Transportation and Distribution of Exogenous JA Revealed by Radioisotope Technique in Hevea brasiliensis%同位素示踪技术研究JA在巴西橡胶树中的运输和分布

    Institute of Scientific and Technical Information of China (English)

    史敏晶; 田维敏

    2012-01-01

    为了研究外源茉莉酸(jasmonic acid,JA)在巴西橡胶树中的移动方向、运输途径以及分布规律,以无性系CATAS7-33-97为实验材料,对其幼嫩萌条进行外施3H-JA和3H-JA+机械伤害处理,用同位素示踪技术对外源3H-JA在萌条不同部位的放射性强度进行了研究.结果表明,外施JA在进入植株体内1h后,大部分集中在施用部位;伤害能明显阻止外源JA进入树皮组织,但同时也阻止进入了的JA再向其他部位转移;新梢中积累的JA明显低于施用部位,但比其他4个部位都高.外源JA在巴西橡胶树中可以同时向上和向下运输,运输的途径主要是韧皮部,但木质部也是运输部位之一.由此可见,在巴西橡胶树中,外源JA能够迅速地被运输到周边部位,代谢旺盛的部位具有易富集JA的能力,而机械伤害对JA在植株体内的分布有明显的影响.%In order to research the mobile direction and approach of exogenous JA as well as regularity of distribution in Hevea brasiliensis.The shoots of clone CATAS7-33-97 were used as the experimental material, which had been treated respectively by applying exogenous 3H-JA, mechanical wounding and exogenous 3H-JA.By using radioisotope technique, the radioactivity in the different sites of shoot was studied.The results showed that the most radioactivity of 3H-JA sustained in the bark of treated site within one hour, and mechanical wounding hindered the entrance of exogenous JA meanwhile held back the entered JA to the around regions.The radioactivity in the sample of extending new shoot was obviously lower than the radioactivity of the treated site bark, but significantly higher than the other four sites.Exogenous JA could be transported upwards and downwards through phloem mainly and xylem secondary.Thus it could be seen that exogenous JA was rapidly transported to the regions around wounded site after entrance, and the vigorous tender site accumulated JA easily.Moreover, mechanical

  11. Landing Techniques in Beach Volleyball

    Science.gov (United States)

    Tilp, Markus; Rindler, Michael

    2013-01-01

    The aims of the present study were to establish a detailed and representative record of landing techniques (two-, left-, and right-footed landings) in professional beach volleyball and compare the data with those of indoor volleyball. Beach volleyball data was retrieved from videos taken at FIVB World Tour tournaments. Landing techniques were compared in the different beach and indoor volleyball skills serve, set, attack, and block with regard to sex, playing technique, and court position. Significant differences were observed between men and women in landings following block actions (χ2(2) = 18.19, p volleyball revealed overall differences both in men (χ2(2) = 161.4, p volleyball players land more often on both feet than indoor volleyball players. Besides the softer surface in beach volleyball, and therefore resulting lower loads, these results might be another reason for fewer injuries and overuse conditions compared to indoor volleyball. Key Points About 1/3 of all jumping actions in beach volleyball result in a landing on one foot. Especially following block situations men land on one foot more often than women. Landing techniques are related to different techniques and positions. Landings on one foot are less common in beach volleyball than indoor volleyball. This could be a reason for fewer injuries and overuse conditions. PMID:24149150

  12. Surface science techniques

    CERN Document Server

    Bracco, Gianangelo

    2013-01-01

    The book describes the experimental techniques employed to study surfaces and interfaces. The emphasis is on the experimental method. Therefore all chapters start with an introduction of the scientific problem, the theory necessary to understand how the technique works and how to understand the results. Descriptions of real experimental setups, experimental results at different systems are given to show both the strength and the limits of the technique. In a final part the new developments and possible extensions of the techniques are presented. The included techniques provide microscopic as well as macroscopic information. They cover most of the techniques used in surface science.

  13. LANDING TECHNIQUES IN BEACH VOLLEYBALL

    Directory of Open Access Journals (Sweden)

    Markus Tilp

    2013-09-01

    Full Text Available The aims of the present study were to establish a detailed and representative record of landing techniques (two-, left-, and right-footed landings in professional beach volleyball and compare the data with those of indoor volleyball. Beach volleyball data was retrieved from videos taken at FIVB World Tour tournaments. Landing techniques were compared in the different beach and indoor volleyball skills serve, set, attack, and block with regard to sex, playing technique, and court position. Significant differences were observed between men and women in landings following block actions (χ²(2 = 18.19, p < 0.01 but not following serve, set, and attack actions. Following blocking, men landed more often on one foot than women. Further differences in landings following serve and attack with regard to playing technique and position were mainly observed in men. The comparison with landing techniques in indoor volleyball revealed overall differences both in men (χ²(2 = 161.4, p < 0.01 and women (χ²(2 = 84.91, p < 0.01. Beach volleyball players land more often on both feet than indoor volleyball players. Besides the softer surface in beach volleyball, and therefore resulting lower loads, these results might be another reason for fewer injuries and overuse conditions compared to indoor volleyball

  14. Emerging optical nanoscopy techniques

    Directory of Open Access Journals (Sweden)

    Montgomery PC

    2015-09-01

    Full Text Available Paul C Montgomery, Audrey Leong-Hoi Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (ICube, Unistra-CNRS, Strasbourg, France Abstract: To face the challenges of modern health care, new imaging techniques with subcellular resolution or detection over wide fields are required. Far field optical nanoscopy presents many new solutions, providing high resolution or detection at high speed. We present a new classification scheme to help appreciate the growing number of optical nanoscopy techniques. We underline an important distinction between superresolution techniques that provide improved resolving power and nanodetection techniques for characterizing unresolved nanostructures. Some of the emerging techniques within these two categories are highlighted with applications in biophysics and medicine. Recent techniques employing wider angle imaging by digital holography and scattering lens microscopy allow superresolution to be achieved for subcellular and even in vivo, imaging without labeling. Nanodetection techniques are divided into four subcategories using contrast, phase, deconvolution, and nanomarkers. Contrast enhancement is illustrated by means of a polarized light-based technique and with strobed phase-contrast microscopy to reveal nanostructures. Very high sensitivity phase measurement using interference microscopy is shown to provide nanometric surface roughness measurement or to reveal internal nanometric structures. Finally, the use of nanomarkers is illustrated with stochastic fluorescence microscopy for mapping intracellular structures. We also present some of the future perspectives of optical nanoscopy. Keywords: microscopy, imaging, superresolution, nanodetection, biophysics, medical imaging

  15. Emerging optical nanoscopy techniques

    Science.gov (United States)

    Montgomery, Paul C; Leong-Hoi, Audrey

    2015-01-01

    To face the challenges of modern health care, new imaging techniques with subcellular resolution or detection over wide fields are required. Far field optical nanoscopy presents many new solutions, providing high resolution or detection at high speed. We present a new classification scheme to help appreciate the growing number of optical nanoscopy techniques. We underline an important distinction between superresolution techniques that provide improved resolving power and nanodetection techniques for characterizing unresolved nanostructures. Some of the emerging techniques within these two categories are highlighted with applications in biophysics and medicine. Recent techniques employing wider angle imaging by digital holography and scattering lens microscopy allow superresolution to be achieved for subcellular and even in vivo, imaging without labeling. Nanodetection techniques are divided into four subcategories using contrast, phase, deconvolution, and nanomarkers. Contrast enhancement is illustrated by means of a polarized light-based technique and with strobed phase-contrast microscopy to reveal nanostructures. Very high sensitivity phase measurement using interference microscopy is shown to provide nanometric surface roughness measurement or to reveal internal nanometric structures. Finally, the use of nanomarkers is illustrated with stochastic fluorescence microscopy for mapping intracellular structures. We also present some of the future perspectives of optical nanoscopy. PMID:26491270

  16. An Exploratory Study of Critical Factors Affecting the Efficiency of Sorting Techniques (Shell, Heap and Treap)

    CERN Document Server

    Folorunso, Olusegun; Salako, Oluwatimilehin

    2012-01-01

    The efficiency of sorting techniques has a significant impact on the overall efficiency of a program. The efficiency of Shell, Heap and Treap sorting techniques in terms of both running time and memory usage was studied, experiments conducted and results subjected to factor analysis by SPSS. The study revealed the main factor affecting these sorting techniques was time taken to sort.

  17. Use of double-layer autologous dermal flap in the treatment of recurrent and/or infected incisional hernias: presentation of the surgical technique and the results of 1-year follow-up-a prospective, consecutive cohort study.

    Science.gov (United States)

    Martis, G; Damjanovich, L

    2016-06-01

    The difficulties of treating recurrent and/or infected incisional hernias are well known in surgical practice. Several surgical techniques and various types of grafts are available for surgeons. This study presents a new surgical technique option together with the results of the 1-year follow-up. The primary aim of the study is to present the surgical technique of the procedure suitable for the treatment of recurrent and/or infected incisional hernias. The secondary aim is to determine the recurrence rate and analyse the surgical complications. The tertiary aim is to present the quality of life test results performed 3, 6 and 12 months after the surgery. The authors evaluated the results of 36 recurrent and/or infected incisional hernia surgeries (11 men, average age 60.6 years; 25 women, average age 58.9 years) performed with their own surgical method in the framework of a tightly controlled, prospective, interventional and observational consecutive cohort study conducted between 1 January 2011 and 31 December 2013 at a university surgical department. The study evaluates the results of the 1-year follow-up period. All 36 patients had at least one recurrence of abdominal wall hernia; 12 of them also had concurrent infection of the synthetic graft and a complicating fistula. The mean BMI was 31.82 kg/m(2) (25.2-43.5 kg/m(2)). The average size of the abdominal wall defect was 145.9 cm(2) (59-275 cm(2)). The abdominal wall reconstruction was performed using an autologous, double-layer dermal flap. The grafts, which had been inserted during previous surgeries, were removed completely. The autologous dermal tissue was prepared using the flap harvested during dermolipectomy. The reconstruction was achieved using a tension-free technique. The essence of the abdominal wall reconstruction is the completion of the abdominal wall defect by a double-layer autologous dermal flap. The original abdominal wall defect was not closed by direct sutures. The quality of the

  18. Revealing interference by continuous variable discordant states.

    Science.gov (United States)

    Meda, A; Olivares, S; Degiovanni, I P; Brida, G; Genovese, M; Paris, M G A

    2013-08-15

    In general, a pair of uncorrelated Gaussian states mixed in a beam splitter (BS) produces a correlated state at the output. However, when the inputs are identical Gaussian states the output state is equal to the input, and no correlations appear, as the interference had not taken place. On the other hand, since physical phenomena do have observable effects, and the BS is there, a question arises on how to reveal the interference between the two beams. We prove theoretically and demonstrate experimentally that this is possible if at least one of the two beams is prepared in a discordant, i.e., Gaussian correlated, state with a third beam. We also apply the same technique to reveal the erasure of polarization information. Our experiment involves thermal states and the results show that Gaussian discordant states, even when they show a positive Glauber P-function, may be useful to achieve specific tasks.

  19. The Comparison Analysis of Test Result of Ultrasonic △ Technique and TOFD Method%超声△法与TOFD法在薄壁电子束焊缝上的检测结果对比分析

    Institute of Scientific and Technical Information of China (English)

    史亦韦; 王乃波; 卢超

    2012-01-01

    采用超声△衍射法和TOFD法对模拟缺陷进行检测,得出了缺陷检测波形图和B/C扫描图.对比分析了超声△衍射法与TOFD法的检测结果.实验表明利用超声△衍射法能够识别近表面垂直表面的面状缺陷,有效地对缺陷进行定位,能够很好地克服表面盲区,对缺陷的检测识别能力不受缺陷方向限制.从检测结果数据可以看出超声△衍射法的检测灵敏度和缺陷识别能力优于TOFD法.%Through the inspection of ultrasonic A technique and TOFD method on simulate flaws, concluded signal oscillogram and B/C scan of flaws. The signal characteristics of ultrasonic A technique and TOFD method were analyzed and interpreted. The results show that the defects which are perpendicular to the surface can be identified and located effectively, and can overcome surface blind area effectively, and the recognition capibility for defects is not limited by the orientation of them. From the results it can be seen that the achieved flaw sensitivity and probability of detection are substantially better than TOFD method.

  20. Research Results Research Results

    Science.gov (United States)

    2009-04-01

    A Highly Efficient Route for Selective Phenol Hydrogenation to Cyclohexanone A Novel Mechanism Employed by KSHV to Maintain the Latent Infection was Revealed Breakthrough in the Synthesis of Interconnected NW/NT and NT/NW/NT Heterojunctions with Branched Topology GABA Transporter-1 Activity Modulates Hippocampal Theta Oscillation and Theta Burst Stimulation-Induced Long-Term Potentiation Meta-analysis of Vitamin D, Calcium and the Prevention of Breast Cancer New Findings on the Origin of TrpRS PKCd Regulates Cortical Radial Migration by Stabilizing the Cdk5 Activator P35 PKU Research Team Publishes Papers on Inhalation Exposure to Pollutant and Cancer Risk Progress of the Research on Arbitrarily Elliptical Invisibility Cloaks An Advance in Complete Oxidation of Formaldehyde at Low Temperatures

  1. Xenon ventilation CT using dual-source and dual-energy technique in children with bronchiolitis obliterans: correlation of xenon and CT density values with pulmonary function test results

    Energy Technology Data Exchange (ETDEWEB)

    Goo, Hyun Woo; Yang, Dong Hyun; Seo, Joon Beom; Chae, Eun Jin; Lee, Jeongjin [University of Ulsan College of Medicine, Department of Radiology and Research Institute of Radiology, Asan Medical Center, Songpa-gu, Seoul (Korea); Hong, Soo-Jong; Yu, Jinho; Kim, Byoung-Ju [University of Ulsan College of Medicine, Department of Pediatrics, Asan Medical Center, Seoul (Korea); Krauss, Bernhard [Siemens Medical Solutions AG-Computed Tomography, Forchheim (Germany)

    2010-09-15

    Xenon ventilation CT using dual-source and dual-energy technique is a recently introduced, promising functional lung imaging method. To expand its clinical applications evidence of additional diagnostic value of xenon ventilation CT over conventional chest CT is required. To evaluate the usefulness of xenon ventilation CT using dual-source and dual-energy technique in children with bronchiolitis obliterans (BO). Seventeen children (age 7-18 years; 11 boys) with BO underwent xenon ventilation CT using dual-source and dual-energy technique. Xenon and CT density values were measured in normal and hyperlucent lung regions on CT and were compared between the two regions. Volumes of hyperlucent regions and ventilation defects were calculated with thresholds determined by visual and histogram-based analysis. Indexed volumes of hyperlucent lung regions and ventilation defects were correlated with pulmonary function test results. Effective doses of xenon CT were calculated. Xenon (14.6 {+-} 6.4 HU vs 26.1 {+-} 6.5 HU; P < 0.001) and CT density (-892.8 {+-} 25.4 HU vs -812.3 {+-} 38.7 HU; P < 0.001) values were significantly lower in hyperlucent regions than in normal lung regions. Xenon and CT density values showed significant positive correlation for the entire lung in 16 children ({gamma} = 0.55 {+-} 0.17, P < 0.001 or =0.017) and for hyperlucent regions in 13 children ({gamma} = 0.44 {+-} 0.16, P < 0.001 or =0.001-0.019). Indexed volumes and volume percentages of hyperlucent lung regions and ventilation defects showed strong negative correlations with forced expiratory volume [FEV1, ({gamma} = -0.64-0.85, P {<=} 0.006)], FEV1/forced vital capacity [FVC, ({gamma} = -0.63-0.84, P {<=} 0.008)], and forced midexpiratory flow rate [FEF{sub 25-75}, ({gamma} = -0.68-0.88, P {<=} 0.002). Volume percentages of xenon ventilation defects (35.0 {+-} 16.4%)] were not significantly different from those of hyperlucent lung regions (38.2 {+-} 18.6%). However, mismatches between the

  2. Evaluation of gravimetric techniques to estimate the microvascular filtration coefficient.

    Science.gov (United States)

    Dongaonkar, R M; Laine, G A; Stewart, R H; Quick, C M

    2011-06-01

    Microvascular permeability to water is characterized by the microvascular filtration coefficient (K(f)). Conventional gravimetric techniques to estimate K(f) rely on data obtained from either transient or steady-state increases in organ weight in response to increases in microvascular pressure. Both techniques result in considerably different estimates and neither account for interstitial fluid storage and lymphatic return. We therefore developed a theoretical framework to evaluate K(f) estimation techniques by 1) comparing conventional techniques to a novel technique that includes effects of interstitial fluid storage and lymphatic return, 2) evaluating the ability of conventional techniques to reproduce K(f) from simulated gravimetric data generated by a realistic interstitial fluid balance model, 3) analyzing new data collected from rat intestine, and 4) analyzing previously reported data. These approaches revealed that the steady-state gravimetric technique yields estimates that are not directly related to K(f) and are in some cases directly proportional to interstitial compliance. However, the transient gravimetric technique yields accurate estimates in some organs, because the typical experimental duration minimizes the effects of interstitial fluid storage and lymphatic return. Furthermore, our analytical framework reveals that the supposed requirement of tying off all draining lymphatic vessels for the transient technique is unnecessary. Finally, our numerical simulations indicate that our comprehensive technique accurately reproduces the value of K(f) in all organs, is not confounded by interstitial storage and lymphatic return, and provides corroboration of the estimate from the transient technique.

  3. Retinal Image Simulation of Subjective Refraction Techniques.

    Science.gov (United States)

    Perches, Sara; Collados, M Victoria; Ares, Jorge

    2016-01-01

    Refraction techniques make it possible to determine the most appropriate sphero-cylindrical lens prescription to achieve the best possible visual quality. Among these techniques, subjective refraction (i.e., patient's response-guided refraction) is the most commonly used approach. In this context, this paper's main goal is to present a simulation software that implements in a virtual manner various subjective-refraction techniques--including Jackson's Cross-Cylinder test (JCC)--relying all on the observation of computer-generated retinal images. This software has also been used to evaluate visual quality when the JCC test is performed in multifocal-contact-lens wearers. The results