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Sample records for techniques provide similar

  1. A Dimensionality Reduction Technique for Efficient Time Series Similarity Analysis

    Science.gov (United States)

    Wang, Qiang; Megalooikonomou, Vasileios

    2008-01-01

    We propose a dimensionality reduction technique for time series analysis that significantly improves the efficiency and accuracy of similarity searches. In contrast to piecewise constant approximation (PCA) techniques that approximate each time series with constant value segments, the proposed method--Piecewise Vector Quantized Approximation--uses the closest (based on a distance measure) codeword from a codebook of key-sequences to represent each segment. The new representation is symbolic and it allows for the application of text-based retrieval techniques into time series similarity analysis. Experiments on real and simulated datasets show that the proposed technique generally outperforms PCA techniques in clustering and similarity searches. PMID:18496587

  2. A Dimensionality Reduction Technique for Efficient Time Series Similarity Analysis.

    Science.gov (United States)

    Wang, Qiang; Megalooikonomou, Vasileios

    2008-03-01

    We propose a dimensionality reduction technique for time series analysis that significantly improves the efficiency and accuracy of similarity searches. In contrast to piecewise constant approximation (PCA) techniques that approximate each time series with constant value segments, the proposed method--Piecewise Vector Quantized Approximation--uses the closest (based on a distance measure) codeword from a codebook of key-sequences to represent each segment. The new representation is symbolic and it allows for the application of text-based retrieval techniques into time series similarity analysis. Experiments on real and simulated datasets show that the proposed technique generally outperforms PCA techniques in clustering and similarity searches.

  3. An efficient similarity measure technique for medical image registration

    Indian Academy of Sciences (India)

    In this paper, an efficient similarity measure technique is proposed for medical image registration. The proposed approach is based on the Gerschgorin circles theorem. In this approach, image registration is carried out by considering Gerschgorin bounds of a covariance matrix of two compared images with normalized ...

  4. Similarity of different lifting techniques in trunk muscular synergies.

    Science.gov (United States)

    Mirakhorlo, Mojtaba; Azghani, Mahmood Reza

    2015-01-01

    Lifting is known to be a major reason for musculoskeletal injuries. In this way, lifting has a crucial effect on human musculoskeletal system and intensity of this impact depends slightly on the selection of techniques. Underlying mechanisms by which trunk muscles are executed during performing lifting are central to biomechanical study of lifting techniques. In the current study, the trunk muscular control mechanisms of lifting are investigated using the synergetic control analysis. Non-negative matrix factorization has been used to extract trunk muscles synergies from their activities - which are computed by a previously validated musculoskeletal model - during different lifting techniques aimed to investigate motor control strategies. Three lifting techniques are considered; stoop, squat and semi-squat. Three synergies account for variety among muscle activation of trunk muscles with related VAF (Variability Account For) of over 95%. Trunk muscle synergy weightings and related time-varying coefficients are calculated for each kind of lifting techniques considering three synergies. Paired correlation coefficients between muscle synergies are all greater than 0.91 (P < 0.05) suggesting that trunk muscle synergies are similar for examined techniques in spite of their kinematic diversity. This similarity can be a result of their common ultimate goal. The acquired results also elucidate the mechanisms of muscle activation patterns that can be exploited in future studies and ergonomic interventions.

  5. Melodic Similarity and Applications Using Biologically-Inspired Techniques

    Directory of Open Access Journals (Sweden)

    Dimitrios Bountouridis

    2017-12-01

    Full Text Available Music similarity is a complex concept that manifests itself in areas such as Music Information Retrieval (MIR, musicological analysis and music cognition. Modelling the similarity of two music items is key for a number of music-related applications, such as cover song detection and query-by-humming. Typically, similarity models are based on intuition, heuristics or small-scale cognitive experiments; thus, applicability to broader contexts cannot be guaranteed. We argue that data-driven tools and analysis methods, applied to songs known to be related, can potentially provide us with information regarding the fine-grained nature of music similarity. Interestingly, music and biological sequences share a number of parallel concepts; from the natural sequence-representation, to their mechanisms of generating variations, i.e., oral transmission and evolution respectively. As such, there is a great potential for applying scientific methods and tools from bioinformatics to music. Stripped-down from biological heuristics, certain bioinformatics approaches can be generalized to any type of sequence. Consequently, reliable and unbiased data-driven solutions to problems such as biological sequence similarity and conservation analysis can be applied to music similarity and stability analysis. Our paper relies on such an approach to tackle a number of tasks and more notably to model global melodic similarity.

  6. Melodic Similarity and Applications Using Biologically-Inspired Techniques

    NARCIS (Netherlands)

    Bountouridis, D.|info:eu-repo/dai/nl/411292412; Brown, Dan; Wiering, F.|info:eu-repo/dai/nl/141928034; Veltkamp, R.C.|info:eu-repo/dai/nl/084742984

    2017-01-01

    Music similarity is a complex concept that manifests itself in areas such as Music Information Retrieval (MIR), musicological analysis and music cognition. Modelling the similarity of two music items is key for a number of music-related applications, such as cover song detection and

  7. An efficient similarity measure technique for medical image registration

    Indian Academy of Sciences (India)

    The similarity measures are tested on the matrix laboratory (MATLAB) plat- form of version 7.0.4. Table 4 shows the comparison of computational time required by various image registration methods. Figures 5a and c of the size 256 × 256 pixels are considered for the calculation of computational time of various similarity ...

  8. Evaluation of mfcc estimation techniques for music similarity

    DEFF Research Database (Denmark)

    Jensen, Jesper Højvang; Christensen, Mads Græsbøll; Murthi, Manohar

    2006-01-01

    Spectral envelope parameters in the form of mel-frequencycepstral coefficients are often used for capturing timbral information of music signals in connection with genre classification applications. In this paper, we evaluate mel-frequencycepstral coefficient (MFCC) estimation techniques, namely...... the classical FFT and linear prediction based implementations and an implementation based on the more recent MVDR spectral estimator. The performance of these methods are evaluated in genre classification using a probabilistic classifier based on Gaussian Mixture models. MFCCs based on fixed order, signal...

  9. Structural similarities between brain and linguistic data provide evidence of semantic relations in the brain.

    Directory of Open Access Journals (Sweden)

    Colleen E Crangle

    Full Text Available This paper presents a new method of analysis by which structural similarities between brain data and linguistic data can be assessed at the semantic level. It shows how to measure the strength of these structural similarities and so determine the relatively better fit of the brain data with one semantic model over another. The first model is derived from WordNet, a lexical database of English compiled by language experts. The second is given by the corpus-based statistical technique of latent semantic analysis (LSA, which detects relations between words that are latent or hidden in text. The brain data are drawn from experiments in which statements about the geography of Europe were presented auditorily to participants who were asked to determine their truth or falsity while electroencephalographic (EEG recordings were made. The theoretical framework for the analysis of the brain and semantic data derives from axiomatizations of theories such as the theory of differences in utility preference. Using brain-data samples from individual trials time-locked to the presentation of each word, ordinal relations of similarity differences are computed for the brain data and for the linguistic data. In each case those relations that are invariant with respect to the brain and linguistic data, and are correlated with sufficient statistical strength, amount to structural similarities between the brain and linguistic data. Results show that many more statistically significant structural similarities can be found between the brain data and the WordNet-derived data than the LSA-derived data. The work reported here is placed within the context of other recent studies of semantics and the brain. The main contribution of this paper is the new method it presents for the study of semantics and the brain and the focus it permits on networks of relations detected in brain data and represented by a semantic model.

  10. Data mining technique for fast retrieval of similar waveforms in Fusion massive databases

    Energy Technology Data Exchange (ETDEWEB)

    Vega, J. [Asociacion EURATOM/CIEMAT Para Fusion, Madrid (Spain)], E-mail: jesus.vega@ciemat.es; Pereira, A.; Portas, A. [Asociacion EURATOM/CIEMAT Para Fusion, Madrid (Spain); Dormido-Canto, S.; Farias, G.; Dormido, R.; Sanchez, J.; Duro, N. [Departamento de Informatica y Automatica, UNED, Madrid (Spain); Santos, M. [Departamento de Arquitectura de Computadores y Automatica, UCM, Madrid (Spain); Sanchez, E. [Asociacion EURATOM/CIEMAT Para Fusion, Madrid (Spain); Pajares, G. [Departamento de Arquitectura de Computadores y Automatica, UCM, Madrid (Spain)

    2008-01-15

    Fusion measurement systems generate similar waveforms for reproducible behavior. A major difficulty related to data analysis is the identification, in a rapid and automated way, of a set of discharges with comparable behaviour, i.e. discharges with 'similar' waveforms. Here we introduce a new technique for rapid searching and retrieval of 'similar' signals. The approach consists of building a classification system that avoids traversing the whole database looking for similarities. The classification system diminishes the problem dimensionality (by means of waveform feature extraction) and reduces the searching space to just the most probable 'similar' waveforms (clustering techniques). In the searching procedure, the input waveform is classified in any of the existing clusters. Then, a similarity measure is computed between the input signal and all cluster elements in order to identify the most similar waveforms. The inner product of normalized vectors is used as the similarity measure as it allows the searching process to be independent of signal gain and polarity. This development has been applied recently to TJ-II stellarator databases and has been integrated into its remote participation system.

  11. Data mining technique for fast retrieval of similar waveforms in Fusion massive databases

    International Nuclear Information System (INIS)

    Vega, J.; Pereira, A.; Portas, A.; Dormido-Canto, S.; Farias, G.; Dormido, R.; Sanchez, J.; Duro, N.; Santos, M.; Sanchez, E.; Pajares, G.

    2008-01-01

    Fusion measurement systems generate similar waveforms for reproducible behavior. A major difficulty related to data analysis is the identification, in a rapid and automated way, of a set of discharges with comparable behaviour, i.e. discharges with 'similar' waveforms. Here we introduce a new technique for rapid searching and retrieval of 'similar' signals. The approach consists of building a classification system that avoids traversing the whole database looking for similarities. The classification system diminishes the problem dimensionality (by means of waveform feature extraction) and reduces the searching space to just the most probable 'similar' waveforms (clustering techniques). In the searching procedure, the input waveform is classified in any of the existing clusters. Then, a similarity measure is computed between the input signal and all cluster elements in order to identify the most similar waveforms. The inner product of normalized vectors is used as the similarity measure as it allows the searching process to be independent of signal gain and polarity. This development has been applied recently to TJ-II stellarator databases and has been integrated into its remote participation system

  12. Intratracheal atomized surfactant provides similar outcomes as bolus surfactant in preterm lambs with respiratory distress syndrome.

    Science.gov (United States)

    Milesi, Ilaria; Tingay, David G; Zannin, Emanuela; Bianco, Federico; Tagliabue, Paolo; Mosca, Fabio; Lavizzari, Anna; Ventura, Maria Luisa; Zonneveld, C Elroy; Perkins, Elizabeth J; Black, Don; Sourial, Magdy; Dellacá, Raffaele L

    2016-07-01

    Aerosolization of exogenous surfactant remains a challenge. This study is aimed to evaluate the efficacy of atomized poractant alfa (Curosurf) administered with a novel atomizer in preterm lambs with respiratory distress syndrome. Twenty anaesthetized lambs, 127 ± 1 d gestational age, (mean ± SD) were instrumented before birth and randomized to receive either (i) positive pressure ventilation without surfactant (Control group), (ii) 200 mg/kg of bolus instilled surfactant (Bolus group) at 10 min of life or (iii) 200 mg/kg of atomized surfactant (Atomizer group) over 60 min from 10 min of life. All lambs were ventilated for 180 min with a standardized protocol. Lung mechanics, regional lung compliance (electrical impedance tomography), and carotid blood flow (CBF) were measured with arterial blood gas analysis. Dynamic compliance and oxygenation responses were similar in the Bolus and Atomizer groups, and both better than Control by 180 min (all P < 0.05; two-way ANOVA). Both surfactant groups demonstrated more homogeneous regional lung compliance throughout the study period. There were no differences in CBFConclusion:In a preterm lamb model, atomized surfactant resulted in similar gas exchange and mechanics as bolus administration. This study suggests evaluation of supraglottic atomization with this system when noninvasive support is warranted.

  13. Can Rural Minimally Invasive Surgery Fellowships Provide Operative Experience Similar to Urban Programs?

    Science.gov (United States)

    Ryan, James Patrick; Borgert, Andrew J; Kallies, Kara J; Carlson, Lea M; McCollister, Howard; Severson, Paul A; Kothari, Shanu N

    2016-01-01

    Operative experience in rural fellowship programs is largely unknown. The 2 of the most rural minimally invasive surgery (MIS)/bariatric fellowships are located in the upper Midwest. We hypothesized that these 2 programs would offer a similar operative experience to other U.S. programs in more urban locations. The 2011 to 2012 and 2012 to 2013 fellowship case logs from 2 rural Midwest programs were compared with case logs from 23 U.S. MIS/bariatric programs. All rural Midwest fellowship graduates completed a survey describing their fellowship experience and current practice. Statistical analysis included Wilcoxon rank-sum test. Setting included the 2 rural Midwest U.S. MIS/bariatric fellowship programs. Graduates from MIS/bariatric fellowship programs participated in the study. Mean volumes for bariatric, foregut, abdominal wall, small intestine, and hepatobiliary cases for rural Midwest fellows vs. other U.S. programs were 123.8 ± 23.7 vs. 150.2 ± 49.2 (p = 0.20); 44.3 ± 19.4 vs. 66.3 ± 35.5 (p = 0.18); 48.3 ± 28.0 vs. 57.9 ± 27.8 (p = 0.58); 11.3 ± 1.9 vs. 12.0 ± 8.7 (p = 0.58); and 55.0 ± 34.8 vs. 48.1 ± 42.6 (p = 0.63), respectively. Mean endoscopy volume was significantly higher among rural Midwest fellows (451.0 ± 395.2 vs. 99.7 ± 83.4; p = 0.05). All rural Midwest fellows reported an adequate number of cases as operating surgeon during fellowship. A total of 60% of fellows currently practice in a rural area. In all, 87% and 13% reported that their fellowship training was extremely or somewhat beneficial to their current practice, respectively. Rural MIS fellowship programs offer a similar operative experience to other U.S. programs. A greater volume of endoscopy cases was observed in rural Midwest fellowships. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  14. Explosive Contamination from Substrate Surfaces: Differences and Similarities in Contamination Techniques using RDX and C-4

    Energy Technology Data Exchange (ETDEWEB)

    C.J. Miller; T.S. Yoder

    2010-06-01

    The amount of time that an explosive is present on the surface of a material is dependent upon the original amount of explosive on the surface, temperature, humidity, rain, etc. This laboratory study focused on looking at similarities and differences in three different surface contamination techniques that are used when performance testing explosive trace detection equipment in an attempt to determine how effective the techniques are at replicating actual field samples. The three techniques used were dry transfer deposition of solutions using the Transportation Security Laboratory (TSL) patented dry transfer techniques (US patent 6470730), direct deposition of explosive standards, and fingerprinting of actual explosives. Explosives were deposited on the surface of one of five substrates using one of the three different deposition techniques. The process was repeated for each surface type using each contamination technique. The surface types used were: 50% cotton/50% polyester as found in T-shirts, 100% cotton with a smooth surface such as that found in a cotton dress shirt, 100% cotton on a rough surface such as that found on canvas or denim, suede leather such as might be found on jackets, purses, or shoes, and metal obtained from a car hood at a junk yard. The samples were not pre-cleaned prior to testing and contained sizing agents, and in the case of the metal, oil and dirt. The substrates were photographed using a Zeiss Discover V12 stereoscope with Axiocam ICc1 3 megapixel digital camera to determine the difference in the crystalline structure and surface contamination in an attempt to determine differences and similarities associated with current contamination techniques.

  15. Explosive Contamination from Substrate Surfaces: Differences and Similarities in Contamination Techniques Using RDX and C-4

    Science.gov (United States)

    Miller, C. J.; Yoder, T. S.

    2010-06-01

    Explosive trace detection equipment has been deployed to airports for more than a decade. During this time, the need for standardized procedures and calibrated trace amounts for ensuring that the systems are operating properly and detecting the correct explosive has been apparent but a standard representative of a fingerprint has been elusive. Standards are also necessary to evaluate instrumentation in the laboratories during development and prior to deployment to determine sample throughput, probability of detection, false positive/negative rates, ease of use by operator, mechanical and/or software problems that may be encountered, and other pertinent parameters that would result in the equipment being unusable during field operations. Since many laboratories do not have access to nor are allowed to handle explosives, the equipment is tested using techniques aimed at simulating the actual explosives fingerprint. This laboratory study focused on examining the similarities and differences in three different surface contamination techniques that are used to performance test explosive trace detection equipment in an attempt to determine how effective the techniques are at replicating actual field samples and to offer scenarios where each contamination technique is applicable. The three techniques used were dry transfer deposition of standard solutions using the Transportation Security Laboratory’s (TSL) patented dry transfer techniques (US patent 6470730), direct deposition of explosive standards onto substrates, and fingerprinting of actual explosives onto substrates. RDX was deposited on the surface of one of five substrates using one of the three different deposition techniques. The process was repeated for each substrate type using each contamination technique. The substrate types used were: 50% cotton/50% polyester as found in T-shirts, 100% cotton with a smooth surface such as that found in a cotton dress shirt, 100% cotton on a rough surface such as that

  16. Olympic weightlifting and plyometric training with children provides similar or greater performance improvements than traditional resistance training.

    Science.gov (United States)

    Chaouachi, Anis; Hammami, Raouf; Kaabi, Sofiene; Chamari, Karim; Drinkwater, Eric J; Behm, David G

    2014-06-01

    A number of organizations recommend that advanced resistance training (RT) techniques can be implemented with children. The objective of this study was to evaluate the effectiveness of Olympic-style weightlifting (OWL), plyometrics, and traditional RT programs with children. Sixty-three children (10-12 years) were randomly allocated to a 12-week control OWL, plyometric, or traditional RT program. Pre- and post-training tests included body mass index (BMI), sum of skinfolds, countermovement jump (CMJ), horizontal jump, balance, 5- and 20-m sprint times, isokinetic force and power at 60 and 300° · s(-1). Magnitude-based inferences were used to analyze the likelihood of an effect having a standardized (Cohen's) effect size exceeding 0.20. All interventions were generally superior to the control group. Olympic weightlifting was >80% likely to provide substantially better improvements than plyometric training for CMJ, horizontal jump, and 5- and 20-m sprint times, whereas >75% likely to substantially exceed traditional RT for balance and isokinetic power at 300° · s(-1). Plyometric training was >78% likely to elicit substantially better training adaptations than traditional RT for balance, isokinetic force at 60 and 300° · s(-1), isokinetic power at 300° · s(-1), and 5- and 20-m sprints. Traditional RT only exceeded plyometric training for BMI and isokinetic power at 60° · s(-1). Hence, OWL and plyometrics can provide similar or greater performance adaptations for children. It is recommended that any of the 3 training modalities can be implemented under professional supervision with proper training progressions to enhance training adaptations in children.

  17. Flow shop scheduling decisions through Techniques for Order Preference by Similarity to an Ideal Solution (TOPSIS

    Directory of Open Access Journals (Sweden)

    Arun Gupta

    2016-07-01

    Full Text Available The flow-shop scheduling problem (FSP has been widely studied in the literature and having a very active research area. Over the last few decades, a number of heuristic/meta-heuristic solution techniques have been developed. Some of these techniques offer excellent effectiveness and efficiency at the expense of substantial implementation efforts and being extremely complicated. This paper brings out the application of a Multi-Criteria Decision Making (MCDM method known as techniques for order preference by similarity to an ideal solution (TOPSIS using different weighting schemes in flow-shop environment. The objective function is identification of a job sequence which in turn would have minimum makespan (total job completion time. The application of the proposed method to flow shop scheduling is presented and explained with a numerical example. The results of the proposed TOPSIS based technique of FSP are also compared on the basis of some benchmark problems and found compatible with the results obtained from other standard procedures.

  18. Distance similarity matrix using ensemble of dimensional data reduction techniques: Vibration and aerocoustic case studies

    Science.gov (United States)

    Lopez, Israel; Sarigul-Klijn, Nesrin

    2009-10-01

    Vibration and acoustic-based health-monitoring techniques are used in the literature to monitor structural health under dynamic environment. In this paper, we propose a damage detection and monitoring method based on a distance similarity matrix of dimensionally reduced data wherein redundancy therein is removed. The matrix similarity approach is generic in nature and has the capability of multiscale representation of datasets. To extract damage-sensitive features, dimensional reduction techniques are applied and compared. An ensemble method of dimensional reduction feature outputs is presented and applied to two case studies. The results supports why ensembles can often perform better than any single-feature extraction method. For the first case study, aeroacoustic datasets are collected from controlled scaled experimental tests of controlled known damaged subscale wing structure. For the second case study, a vibration experiment study is used for abrupt change detection and tracking. The results of the two case studies demonstrate that the proposed method is very effective in detecting abrupt changes and the ensemble method developed here can be used for deterioration tracking.

  19. Finding the Better of Two Similar Designs by Monte Carlo Techniques

    DEFF Research Database (Denmark)

    Becker, Peter W.

    1974-01-01

    . The fraction which meets or exceeds the criterion is called the yield. Monte Carlo techniques can be used to simulate the population of systems and thus to estimate the ranking of two designs. The first result presented in the paper is a derivation of the probability that one design is better than another......, along with confidence limits for that probability. If the two designs are topologically the same, i.e., they differ only in the nominal values and actual distributions of true parameter values, then the same set of random numbers can be used for one simulation of each design. Due to the similarity...... there may be a positive correlation between the 2 results which can then be used to narrow the confidence limits from the crude method mentioned above. The second result is a derivation of these narrow confidence limits....

  20. Molecular techniques to distinguish morphologically similar Hydrilla verticillata, Egeria densa, Elodea nuttallii, and Elodea canadensis

    Science.gov (United States)

    Rybicki, Nancy B.; Kirshtein, Julie D.; Voytek, Mary A.

    2013-01-01

    The four submerged aquatic species, hydrilla (Hydrilla verticillata [monoecious and dioecious]), Brazilian waterweed (Egeria densa), Canadian waterweed (Elodea canadensis), and western waterweed (Elodea nuttallii), are difficult to positively identify because of their morphological similarity to each other, resulting in possible misidentification. This limits our ability to understand their past and present distribution, which is important in aquatic plant management. We investigated a molecular technique to identify these species, which are problematic because of their invasive nature on multiple continents. Approximately 100 samples of these species, ranging in age from 40-yr-old herbarium samples to recently collected plants, were collected from regions across the United States. The distribution and range of the samples collected in this research were compared to those reported in the literature. We confirmed information on the current wide distribution of both hydrilla biotypes in the United States and discovered that hydrilla had actually invaded the waterways near Washington, DC 6 yr earlier than originally reported. In addition, we found evidence of the confusion, dating back to the 1980s, between Canadian waterweed and western waterweed in the mid-Atlantic region of the United States. Canadian waterweed was previously reported as common and western waterweed as rare; however, our samples indicate the opposite is true. This information indicates there is a need for investigators to anticipate the spread of hydrilla populations to northern U.S. waterways, where it will compete with existing plant species, including Canadian and western waterweeds. Our ability to confirm distribution and pace of spread of invasive and noninvasive species will improve with increased application of molecular techniques.

  1. DISTINCTION OF MECHANICALLY PROCESSED WOOD SURFACES WITH SIMILAR QUALITIES USING SUNSET LASER TECHNIQUE

    Directory of Open Access Journals (Sweden)

    Anna Carolina de Almeida Andrade

    2016-06-01

    Full Text Available The ASTM D 1666-11 (2011 norm classifies the quality of wood surface pieces after its mechanical processing. Although this classification is difficult to achieve visually, the use of some tools, such as solid state laser, can facilitate this classification. The aim of this work was to evaluate the use of sunset laser to qualify mechanically processed surfaces with similar visual qualities. We used a log from the base of a Khaya ivorensis tree and one from a K. senegalensis tree, both 11 years old. 22 specimens of dimensions 600x140x30 mm (CxLxE were made of each species. The specimens were flattened with speeds of 2400, 3600 and 4000 min-1 and advanced speeds were predetermined in 6 and 15 m.min-1. Then the samples were illuminated with sunset laser and photographed at high resolution, the images were transferred to the software Image J. To evaluate the sunset laser, areas of defects in wood that are classified as regular and bad by ASTM D 1666-11 (2011 were used. There was a difference in classification of wood defects between the two methods used, from the 31 specimens classified as regularly by visual analysis, 8 of them were classified as bad by the laser method. The use of solid-state laser in the sunset laser technique was more efficient in evaluating small differences in mechanically processed wood defects compared to visual evaluation.

  2. Native and non-native plants provide similar refuge to invertebrate prey, but less than artificial plants.

    Directory of Open Access Journals (Sweden)

    Bart M C Grutters

    Full Text Available Non-native species introductions are widespread and can affect ecosystem functioning by altering the structure of food webs. Invading plants often modify habitat structure, which may affect the suitability of vegetation as refuge and could thus impact predator-prey dynamics. Yet little is known about how the replacement of native by non-native vegetation affects predator-prey dynamics. We hypothesize that plant refuge provisioning depends on (1 the plant's native status, (2 plant structural complexity and morphology, (3 predator identity, and (4 prey identity, as well as that (5 structurally similar living and artificial plants provide similar refuge. We used aquatic communities as a model system and compared the refuge provided by plants to macroinvertebrates (Daphnia pulex, Gammarus pulex and damselfly larvae in three short-term laboratory predation experiments. Plant refuge provisioning differed between plant species, but was generally similar for native (Myriophyllum spicatum, Ceratophyllum demersum, Potamogeton perfoliatus and non-native plants (Vallisneria spiralis, Myriophyllum heterophyllum, Cabomba caroliniana. However, plant refuge provisioning to macroinvertebrate prey depended primarily on predator (mirror carp: Cyprinus carpio carpio and dragonfly larvae: Anax imperator and prey identity, while the effects of plant structural complexity were only minor. Contrary to living plants, artificial plant analogues did improve prey survival, particularly with increasing structural complexity and shoot density. As such, plant rigidity, which was high for artificial plants and one of the living plant species evaluated in this study (Ceratophyllum demersum, may interact with structural complexity to play a key role in refuge provisioning to specific prey (Gammarus pulex. Our results demonstrate that replacement of native by structurally similar non-native vegetation is unlikely to greatly affect predator-prey dynamics. We propose that

  3. Statistical Techniques for Analyzing Process or "Similarity" Data in TID Hardness Assurance

    Science.gov (United States)

    Ladbury, R.

    2010-01-01

    We investigate techniques for estimating the contributions to TID hardness variability for families of linear bipolar technologies, determining how part-to-part and lot-to-lot variability change for different part types in the process.

  4. Weak hierarchies associated with similarity measures--an additive clustering technique.

    Science.gov (United States)

    Bandelt, H J; Dress, A W

    1989-01-01

    A new and apparently rather useful and natural concept in cluster analysis is studied: given a similarity measure on a set of objects, a sub-set is regarded as a cluster if any two objects a, b inside this sub-set have greater similarity than any third object outside has to at least one of a, b. These clusters then form a closure system which can be described as a hypergraph without triangles. Conversely, given such a system, one may attach some weight to each cluster and then compose a similarity measure additively, by letting the similarity of a pair be the sum of weights of the clusters containing that particular pair. The original clusters can be reconstructed from the obtained similarity measure. This clustering model is thus located between the general additive clustering model of Shepard and Arabie (1979) and the standard hierarchical model. Potential applications include fitting dendrograms with few additional nonnested clusters and simultaneous representation of some families of multiple dendrograms (in particular, two-dendrogram solutions), as well as assisting the search for phylogenetic relationships by proposing a somewhat larger system of possibly relevant "family groups", from which an appropriate choice (based on additional insight or individual preferences) remains to be made.

  5. Convergent Evolution Provides Evidence of Similar Radiations in Shell Shape in the Turtle Families Emydidae and Geoemydidae

    OpenAIRE

    McLaughlin, Connor

    2016-01-01

    We investigated phenotypic diversification in the species-rich and ecologically diverse turtle families Emydidae and Geoemydidae. In particular, we were interested in whether these groups, with many ecologically and morphologically similar species, show similar patterns of evolutionary radiation. We focused on directions of evolution and evolutionary allometry; we also quantitatively investigated whether two supposed morphological analogs shared within the two groups (e.g., “Box Turtles” and ...

  6. The Chitranjan Ranawat Award: Periarticular injections and femoral & sciatic blocks provide similar pain relief after TKA: a randomized clinical trial.

    Science.gov (United States)

    Spangehl, Mark J; Clarke, Henry D; Hentz, Joseph G; Misra, Lopa; Blocher, Joshua L; Seamans, David P

    2015-01-01

    Two of the more common methods of pain management after TKA are peripheral nerve blocks and intraarticular/periarticular injections. However, we are not aware of any study directly comparing the commonly used combination of a continuous femoral block given with a single-shot sciatic block with that of a periarticular injection after TKA. This randomized clinical trial compared a combined femoral and sciatic nerve block with periarticular injection as part of a multimodal pain protocol after total knee arthroplasty with respect to (1) pain; (2) narcotic use; (3) quadriceps function and length of stay; and (4) peripheral nerve complications. One hundred sixty patients completed randomization into two treatment arms: (1) peripheral nerve blocks (PNB; n=79) with an indwelling femoral nerve catheter and a single shot sciatic block; or (2) periarticular injection (PAI; n=81) using ropivacaine, epinephrine, ketorolac, and morphine. All patients received standardized general anesthesia and oral medications. The primary outcome was postoperative pain, on a 0 to 10 scale, measured on the afternoon of postoperative day 1 (POD 1). Secondary outcomes were narcotic use, quadriceps function, length of stay, and peripheral nerve complications. Mean pain scores on the afternoon of POD 1 were not different between groups (PNB group: 2.9 [SD 2.4]; PAI group: 3.0 [SD 2.2]; 95% confidence interval, -0.8 to 0.6; p=0.76). Mean pain scores taken at three times points on POD 1 were also similar between groups. Hospital length of stay was shorter for the PAI group (2.44 days [SD 0.65] versus 2.84 days [SD 1.34] for the PNB group; p=0.02). Narcotic consumption was higher the day of surgery for the PAI group (PAI group: 11.7 mg morphine equivalents [SD 13.1]; PNB group: 4.6 mg [SD 9.1]; pblocks. Periarticular injections provide adequate pain relief, are simple to use, and avoid the potential complications associated with nerve blocks. Level I, therapeutic study. See Guidelines for Authors for

  7. A method for analyzing the business case for provider participation in the National Cancer Institute's Community Clinical Oncology Program and similar federally funded, provider-based research networks.

    Science.gov (United States)

    Reiter, Kristin L; Song, Paula H; Minasian, Lori; Good, Marjorie; Weiner, Bryan J; McAlearney, Ann Scheck

    2012-09-01

    The Community Clinical Oncology Program (CCOP) plays an essential role in the efforts of the National Cancer Institute (NCI) to increase enrollment in clinical trials. Currently, there is little practical guidance in the literature to assist provider organizations in analyzing the return on investment (ROI), or business case, for establishing and operating a provider-based research network (PBRN) such as the CCOP. In this article, the authors present a conceptual model of the business case for PBRN participation, a spreadsheet-based tool and advice for evaluating the business case for provider participation in a CCOP organization. A comparative, case-study approach was used to identify key components of the business case for hospitals attempting to support a CCOP research infrastructure. Semistructured interviews were conducted with providers and administrators. Key themes were identified and used to develop the financial analysis tool. Key components of the business case included CCOP start-up costs, direct revenue from the NCI CCOP grant, direct expenses required to maintain the CCOP research infrastructure, and incidental benefits, most notably downstream revenues from CCOP patients. The authors recognized the value of incidental benefits as an important contributor to the business case for CCOP participation; however, currently, this component is not calculated. The current results indicated that providing a method for documenting the business case for CCOP or other PBRN involvement will contribute to the long-term sustainability and expansion of these programs by improving providers' understanding of the financial implications of participation. Copyright © 2011 American Cancer Society.

  8. Swarm Intelligence: New Techniques for Adaptive Systems to Provide Learning Support

    Science.gov (United States)

    Wong, Lung-Hsiang; Looi, Chee-Kit

    2012-01-01

    The notion of a system adapting itself to provide support for learning has always been an important issue of research for technology-enabled learning. One approach to provide adaptivity is to use social navigation approaches and techniques which involve analysing data of what was previously selected by a cluster of users or what worked for…

  9. A Similarity-Ranking Method on Semantic Computing for Providing Information-Services in Station-Concierge System

    Directory of Open Access Journals (Sweden)

    Motoki Yokoyama

    2017-07-01

    Full Text Available The prevalence of smartphones and wireless broadband networks have been progressing as a new Railway infomration environment. According to the spread of such devices and information technology, various types of information can be obtained from databases connected to the Internet. One scenario of obtaining such a wide variety of information resources is in the phase of user’s transportation. This paper proposes an information provision system, named the Station Concierge System that matches the situation and intention of passengers. The purpose of this system is to estimate the needs of passengers like station staff or hotel concierge and to provide information resources that satisfy user’s expectations dynamically. The most important module of the system is constructed based on a new information ranking method for passenger intention prediction and service recommendation. This method has three main features, which are (1 projecting a user to semantic vector space by using her current context, (2 predicting the intention of a user based on selecting a semantic vector subspace, and (3 ranking the services by a descending order of relevant scores to the user’ intention. By comparing the predicted results of our method with those of two straightforward computation methods, the experimental studies show the effectiveness and efficiency of the proposed method. Using this system, users can obtain transit information and service map that dynamically matches their context.

  10. EVALUATION OF THE METERED-DOSE INHALER TECHNIQUE AMONG HEALTHCARE PROVIDERS

    Directory of Open Access Journals (Sweden)

    E. Nadi F. Zeraati

    2005-07-01

    Full Text Available Poor inhaler technique is a common problem both in asthmatic patients and healthcare providers, which contributes to poor asthma control. This study was performed to evaluate the adequacy of metered-dose inhaler (MDI technique in a sample of physicians and nurses practicing in hospitals of Hamadan University of Medical Sciences. A total of 173 healthcare providers voluntary participated in this study. After the participants answered a questionnaire aimed at identifying their involvement in MDI prescribing and counseling, a trained observer assessed their MDI technique using a checklist of nine steps. Of the 173 participants, 35 (20.2% were physicians and 138 (79.8% were nurses. Only 12 participants (6.93% performed all steps correctly. Physicians performed essential steps significantly better than nurses (85.7% vs. 63.8%, P < 0.05. The majority of healthcare providers responsible for instructing patients on the correct MDI technique were unable to perform this technique correctly, indicating the need for regular formal training programs on inhaler techniques.

  11. Utilising three-dimensional printing techniques when providing unique assistive devices: A case report.

    Science.gov (United States)

    Day, Sarah Jane; Riley, Shaun Patrick

    2018-02-01

    The evolution of three-dimensional printing into prosthetics has opened conversations about the availability and cost of prostheses. This report will discuss how a prosthetic team incorporated additive manufacture techniques into the treatment of a patient with a partial hand amputation to create and test a unique assistive device which he could use to hold his French horn. Case description and methods: Using a process of shape capture, photogrammetry, computer-aided design and finite element analysis, a suitable assistive device was designed and tested. The design was fabricated using three-dimensional printing. Patient satisfaction was measured using a Pugh's Matrix™, and a cost comparison was made between the process used and traditional manufacturing. Findings and outcomes: Patient satisfaction was high. The three-dimensional printed devices were 56% cheaper to fabricate than a similar laminated device. Computer-aided design and three-dimensional printing proved to be an effective method for designing, testing and fabricating a unique assistive device. Clinical relevance CAD and 3D printing techniques can enable devices to be designed, tested and fabricated cheaper than when using traditional techniques. This may lead to improvements in quality and accessibility.

  12. Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world

    Directory of Open Access Journals (Sweden)

    Mitsue Meguro

    Full Text Available Abstract Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. Objectives: To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD. Methods: Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Results: Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. Conclusions: We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

  13. Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world.

    Science.gov (United States)

    Meguro, Mitsue; Ishizaki, Junichi; Meguro, Kenichi

    2009-01-01

    Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD). Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

  14. Pertimbangan Pembelian Oleh-oleh Pada Rute Perjalananan Wisatawan Menggunakan Technique for Others Preference by Similarity to Ideal Solution (TOPSIS

    Directory of Open Access Journals (Sweden)

    Oliver Samuel Simanjuntak

    2017-07-01

    Full Text Available Era modernisasi membawa dampak terhadap kebutuhan masyarakat, yaitu kebutuhan masyarakat melaksanakan pekerjaannya secara cepat dan mudah. Pada khususnya wisatawan, wisatawan yang mengunjungi suatu wilayah berkeinginan cepat dan mudah dalam pencarian oleh-oleh. Dalam pencarian oleh-oleh, wisatawan mengalami kendala dalam penentuan lokasi toko dan oleh-oleh Wisatawan harus mencari toko oleh-oleh secara manual. Aplikasi mobile merupakan salah satu solusi dalam pencarian informasi yang sering digunakan, karena aplikasi mobile dapat berguna dimanapun berada dan kapanpun waktunya. Tersedianya aplikasi mobile  juga sering dimanfaatkan masyarakat untuk mencari lokasi suatu tempat atau tujuan menggunakan Maps. Selain itu seiring dengan perkembangan teknologi, sekarang aplikasi mobile juga di manfaatkan dalam proses jual-beli secara online. Hal ini memberikan kemudahan bagi masyarakat dalam membantu, serta menyelesaikan pekerjaannya secara tepat, dan praktis. Aplikasi berbasis Android ini dibangun menggunakan bahasa pemprograman java dengan memanfaatkan metode TOPSIS (Technique For Others Preference by Similarity to Ideal Solution untuk memberikan pertimbangan kepada pengguna, serta memanfaatkan GoogleMaps API. Dengan aplikasi ini para wisatawan dapat menemukan toko oleh-oleh dan oleh-oleh secara bersamaan berdasarkan rute perjalanan. Selain itu, aplikasi ini,memberikan keuntungan kepada para pemilik toko oleh-oleh untuk menjual oleh-oleh secara online. Serta beberapa fitur yang menunjang proses jual-beli.

  15. An 11-Year Review of Keratoplasty in a Tertiary Referral Center in Turkey: Changing Surgical Techniques for Similar Indications.

    Science.gov (United States)

    Bozkurt, Tahir Kansu; Acar, Banu; Kilavuzoglu, Ayşe Ebru; Akdemir, Mehmet Orçun; Hamilton, David Rex; Cosar Yurteri, Cemile Banu; Acar, Suphi

    2017-11-01

    Study aims to evaluate the indications and surgical techniques for corneal transplantation and to report changes in trends for preferred keratoplasty surgical techniques. Clinical records of 815 consecutive corneal transplantations between January 1, 2004 and December 31, 2014 in Haydarpasa Numune Training and Research Hospital Eye Clinic were analyzed and classified into seven broad groups according to indications. Main outcome measures were change of leading indications and trends for surgical techniques. Leading indications for keratoplasty were keratoconus (KCN) (27.7%), bullous keratopathy (BK) (23%), postinfectious corneal scars (13.5%), regrafts (13.1%), corneal dystrophies (12.1%), and noninfectious corneal scars (5.4%). Regrafts were the only indication with a significantly increasing trend (Ptechniques including deep anterior lamellar keratoplasty (DALK) and Descemet stripping automated endothelial keratoplasty (DSAEK), there was a significant increasing trend in number and percentage of both LK techniques (DALK; P=0.001 and P=0.007, and DSAEK; Ptechnique for KCN and BK indications, (P=0.007 and P=0.01, respectively). Although PK was the most common surgical technique over the 11-year period (54.7%), both anterior and posterior LK techniques showed an emerging trend as the procedures of choice when indicated. No major shift was observed in the clinical indications for corneal transplantation over the previous 11 years, except for regrafts. Lamellar keratoplasty techniques largely overtook the PK technique, but PK was still the overall preferred technique in the era when both LK techniques were used.

  16. Damage control and austere environment external fixation: techniques for the civilian provider.

    Science.gov (United States)

    Gordon, Wade T; Grijalva, Steven; Potter, Benjamin K

    2012-01-01

    Extremity injuries associated with natural disasters and combat are typically high-energy, often open injuries, and routinely represent only part of the scope of injury to a poly-traumatized patient. The early management of these injuries is normally performed in austere environments, and relies heavily on the principles of damage control orthopaedics, with external fixation of associated long bone and peri-articular fractures. While the general principles of ATLS, wound management, and external fixation do not differ from that performed in the setting of civilian trauma, there are special considerations and alterations in standard practice that become necessary when providing this care in an austere environment. The purpose of this article is to review the principles and techniques of damage control orthopaedics and external fixation in the management of extremity trauma in the setting of combat- and natural disaster-related injuries.

  17. Short-arm human centrifugation with 0.4g at eye and 0.75g at heart level provides similar cerebrovascular and cardiovascular responses to standing.

    Science.gov (United States)

    Goswami, Nandu; Bruner, Michelle; Xu, Da; Bareille, Marie-Pierre; Beck, Arnaud; Hinghofer-Szalkay, Helmut; Blaber, Andrew P

    2015-07-01

    Orthostatic intolerance continues to be a problem with astronauts upon return to Earth as a result of cerebral and cardiovascular adaptations to weightlessness. We tested the hypothesis that artificial gravity from a short-arm human centrifuge (SAHC) could provide cerebral and cardiovascular stimuli similar to upright posture and thereby serve as a suitable countermeasure. We compared cardiovascular and cerebrovascular responses before, during, and after exposure to hyper-G with that of standing in healthy young participants. The head was positioned such that the middle cerebral artery (MCA) was 0.46 m from the center of rotation. Two levels of hyper-G that provided 1g and 2g at foot level were investigated. Continuous blood pressure, heart rate, calf blood volume, MCA mean blood flow velocity (MFV) and end-tidal CO2 were measured. Blood pressure at the level of the MCA (BP-MCA) and MFV was reduced during stand and at 2g. The relationship between MFV and BP-MCA at 2g was different from supine and similar to standing, while 1g centrifugation was not different from supine. The cardiovascular system was also not different from supine at 1g but was similarly challenged in 2g compared to stand. Our data suggest that short-arm centrifugation 2g at the feet, with the head offset 0.5 m from the center, provides similar cardiovascular and cerebral responses to standing. This supports the hypothesis that passive 2g SAHC exposure at the feet could be used as a countermeasure for in-flight cardiovascular and cerebrovascular deconditioning.

  18. Measurement of soil water erosion in Africa: the potential support provided by nuclear techniques

    Science.gov (United States)

    Mabit, Lionel

    2010-05-01

    Conservation of soil and water resources has become a major agronomic and environmental concern. Degradation phenomena, such as erosion, desertification and salinization affect 65% of soils worldwide. Soil degradation is currently affecting 1.9 billion hectares and is increasing at a rate of 5 to 7 million hectares each year. Almost 50% of 133 million ha degraded soils by overexploitation are located in Africa. The degradation of arable lands affects especially arid areas with poor vegetation cover and tropical areas with high intensity rainfall. Water erosion is by far the most common type of land degradation in Africa. Accelerated erosion decreases soil productivity, increases sedimentation and is related to environmental pollution problems in agro-ecosystems. To control soil erosion there is a need to assess the impact of major land use and the effectiveness of specific soil conservation technologies using various approaches. Effective erosion control starts with the knowledge of soil erosion rates and mechanisms. In Africa, various research projects on water erosion have been implemented involving different conventional techniques such as remote sensing, morphometric investigation, sediment transport models and sediment loading measurements, runoff plots and rainfall erosivity measurements. However, only limited quantitative data on erosion and sedimentation magnitude under African agroenvironmental condition are available. Traditional monitoring and modeling techniques for soil water erosion require many parameters and years of measurements of (inter-annual and mid-term) climatic variability and cropping practices. Conventional erosion and sedimentation methods are limited to provide mid-term trends in soil erosion, however fallout radionuclides (FRN) - e.g. 137-Cs, 210-Pb and 7-Be - have proven to be very powerful tools to trace soil erosion and sedimentation within the landscape from plot to basin scale. FRN techniques allow the estimation of short and

  19. Coagulant plus ballast technique provides a rapid mitigation of cyanobacterial nuisance.

    Directory of Open Access Journals (Sweden)

    Natalia P Noyma

    Full Text Available Cyanobacteria blooms are a risk to environmental health and public safety due to the potent toxins certain cyanobacteria can produce. These nuisance organisms can be removed from water bodies by biomass flocculation and sedimentation. Here, we studied the efficacy of combinations of a low dose coagulant (poly-aluminium chloride-PAC-or chitosan with different ballast compounds (red soil, bauxite, gravel, aluminium modified zeolite and lanthanum modified bentonite to remove cyanobacterial biomass from water collected in Funil Reservoir (Brazil. We tested the effect of different cyanobacterial biomass concentrations on removal efficiency. We also examined if zeta potential was altered by treatments. Addition of low doses of PAC and chitosan (1-8 mg Al L-1 to the cyanobacterial suspensions caused flock formation, but did not settle the cyanobacteria. When those low dose coagulants were combined with ballast, effective settling in a dose-dependent way up to 99.7% removal of the flocks could be achieved without any effect on the zeta potential and thus without potential membrane damage. Removal efficacy was influenced by the cyanobacterial biomass and at higher biomass more ballast was needed to achieve good removal. The combined coagulant-ballast technique provides a promising alternative to algaecides in lakes, ponds and reservoirs.

  20. Applying BI Techniques To Improve Decision Making And Provide Knowledge Based Management

    Directory of Open Access Journals (Sweden)

    Alexandra Maria Ioana FLOREA

    2015-07-01

    Full Text Available The paper focuses on BI techniques and especially data mining algorithms that can support and improve the decision making process, with applications within the financial sector. We consider the data mining techniques to be more efficient and thus we applied several techniques, supervised and unsupervised learning algorithms The case study in which these algorithms have been implemented regards the activity of a banking institution, with focus on the management of lending activities.

  1. One-stage exchange with antibacterial hydrogel coated implants provides similar results to two-stage revision, without the coating, for the treatment of peri-prosthetic infection.

    Science.gov (United States)

    Capuano, Nicola; Logoluso, Nicola; Gallazzi, Enrico; Drago, Lorenzo; Romanò, Carlo Luca

    2018-03-16

    Aim of this study was to verify the hypothesis that a one-stage exchange procedure, performed with an antibiotic-loaded, fast-resorbable hydrogel coating, provides similar infection recurrence rate than a two-stage procedure without the coating, in patients affected by peri-prosthetic joint infection (PJI). In this two-center case-control, study, 22 patients, treated with a one-stage procedure, using implants coated with an antibiotic-loaded hydrogel [defensive antibacterial coating (DAC)], were compared with 22 retrospective matched controls, treated with a two-stage revision procedure, without the coating. At a mean follow-up of 29.3 ± 5.0 months, two patients (9.1%) in the DAC group showed an infection recurrence, compared to three patients (13.6%) in the two-stage group. Clinical scores were similar between groups, while average hospital stay and antibiotic treatment duration were significantly reduced after one-stage, compared to two-stage (18.9 ± 2.9 versus 35.8 ± 3.4 and 23.5 ± 3.3 versus 53.7 ± 5.6 days, respectively). Although in a relatively limited series of patients, our data shows similar infection recurrence rate after one-stage exchange with DAC-coated implants, compared to two-stage revision without coating, with reduced overall hospitalization time and antibiotic treatment duration. These findings warrant further studies in the possible applications of antibacterial coating technologies to treat implant-related infections. III.

  2. 3D–2D image registration for target localization in spine surgery: investigation of similarity metrics providing robustness to content mismatch

    Science.gov (United States)

    De Silva, T; Uneri, A; Ketcha, M D; Reaungamornrat, S; Kleinszig, G; Vogt, S; Aygun, N; Lo, S-F; Wolinsky, J-P; Siewerdsen, J H

    2016-01-01

    In image-guided spine surgery, robust three-dimensional to two-dimensional (3D–2D) registration of preoperative computed tomography (CT) and intraoperative radiographs can be challenged by the image content mismatch associated with the presence of surgical instrumentation and implants as well as soft-tissue resection or deformation. This work investigates image similarity metrics in 3D–2D registration offering improved robustness against mismatch, thereby improving performance and reducing or eliminating the need for manual masking. The performance of four gradient-based image similarity metrics (gradient information (GI), gradient correlation (GC), gradient information with linear scaling (GS), and gradient orientation (GO)) with a multi-start optimization strategy was evaluated in an institutional review board-approved retrospective clinical study using 51 preoperative CT images and 115 intraoperative mobile radiographs. Registrations were tested with and without polygonal masks as a function of the number of multistarts employed during optimization. Registration accuracy was evaluated in terms of the projection distance error (PDE) and assessment of failure modes (PDE > 30 mm) that could impede reliable vertebral level localization. With manual polygonal masking and 200 multistarts, the GC and GO metrics exhibited robust performance with 0% gross failures and median PDE 14%; however, GO maintained robustness with a 0% gross failure rate. Overall, the GI, GC, and GS metrics were susceptible to registration errors associated with content mismatch, but GO provided robust registration (median PDE = 5.5 mm, 2.6 mm IQR) without manual masking and with an improved runtime (29.3 s). The GO metric improved the registration accuracy and robustness in the presence of strong image content mismatch. This capability could offer valuable assistance and decision support in spine level localization in a manner consistent with clinical workflow. PMID:26992245

  3. 3D-2D image registration for target localization in spine surgery: investigation of similarity metrics providing robustness to content mismatch

    Science.gov (United States)

    De Silva, T.; Uneri, A.; Ketcha, M. D.; Reaungamornrat, S.; Kleinszig, G.; Vogt, S.; Aygun, N.; Lo, S.-F.; Wolinsky, J.-P.; Siewerdsen, J. H.

    2016-04-01

    In image-guided spine surgery, robust three-dimensional to two-dimensional (3D-2D) registration of preoperative computed tomography (CT) and intraoperative radiographs can be challenged by the image content mismatch associated with the presence of surgical instrumentation and implants as well as soft-tissue resection or deformation. This work investigates image similarity metrics in 3D-2D registration offering improved robustness against mismatch, thereby improving performance and reducing or eliminating the need for manual masking. The performance of four gradient-based image similarity metrics (gradient information (GI), gradient correlation (GC), gradient information with linear scaling (GS), and gradient orientation (GO)) with a multi-start optimization strategy was evaluated in an institutional review board-approved retrospective clinical study using 51 preoperative CT images and 115 intraoperative mobile radiographs. Registrations were tested with and without polygonal masks as a function of the number of multistarts employed during optimization. Registration accuracy was evaluated in terms of the projection distance error (PDE) and assessment of failure modes (PDE  >  30 mm) that could impede reliable vertebral level localization. With manual polygonal masking and 200 multistarts, the GC and GO metrics exhibited robust performance with 0% gross failures and median PDE  interquartile range (IQR)) and a median runtime of 84 s (plus upwards of 1-2 min for manual masking). Excluding manual polygonal masks and decreasing the number of multistarts to 50 caused the GC-based registration to fail at a rate of  >14% however, GO maintained robustness with a 0% gross failure rate. Overall, the GI, GC, and GS metrics were susceptible to registration errors associated with content mismatch, but GO provided robust registration (median PDE  =  5.5 mm, 2.6 mm IQR) without manual masking and with an improved runtime (29.3 s). The GO metric

  4. Novel no touch technique of saphenous vein harvesting: Is great graft patency rate provided?

    Directory of Open Access Journals (Sweden)

    Nikolaos A Papakonstantinou

    2016-01-01

    Full Text Available Coronary artery bypass grafting surgery effectively relieves signs and symptoms of myocardial ischemia. The left internal thoracic artery (LITA graft is the gold standard having 90-95% patency rate at 10 years, whereas only 50% of saphenous vein (SV grafts are patent at 10 years. However, there is a novel "no touch" technique in order to harvest an SV complete with its cushion of surrounding tissue, thus maintaining its endothelium-intact. Significantly superior short- and long-term graft patency rates comparable to LITA grafts can be achieved. Consequently, the SV may be revived as an important conduit in coronary artery bypass surgery.

  5. Ultrasound-guided transversus abdominis plane block in patients undergoing open inguinal hernia repair: 0.125% bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine.

    Science.gov (United States)

    Erdoğan Arı, Dilek; Yıldırım Ar, Arzu; Karadoğan, Firdevs; Özcabı, Yetkin; Koçoğlu, Ayşegül; Kılıç, Fatih; Akgün, Fatma Nur

    2016-02-01

    To evaluate the effectiveness of 0.125% bupivacaine compared to 0.25% bupivacaine for ultrasound-guided transversus abdominis plane (TAP) block in patients undergoing open inguinal hernia repair. Randomized, double-blind study. Educational and research hospital. Forty adult patients of American Society of Anesthesiologists physical status I-III undergoing elective primary unilateral open inguinal hernia repair under spinal anesthesia. Patients in group I received 20 mL of 0.25% bupivacaine, whereas patients in group II received 20 mL of 0.125% bupivacaine for TAP block at the end of the surgery. Pain intensity was assessed at rest and during coughing using 10-cm visual analog scale score at 5, 15, 30, and 45 minutes and 1, 2, 4, 6, 12, and 24 hours after TAP block. Morphine consumption and time to first morphine requirement were recorded. Visual analog scale scores at rest and during coughing were not significantly different between groups at all time points measured. Twenty-four hours of morphine consumption (7.72±7.33 mg in group I and 6.06±5.20 mg in group II; P=.437) and time to first morphine requirement (182.35±125.16 minutes in group I and 143.21±87.28 minutes in group II; P=.332) were not different between groups. 0.125% Bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine for ultrasound-guided TAP block in patients undergoing open inguinal hernia repair. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Multi-objective clustering technique based on k-nodes update policy and similarity matrix for mining communities in social networks

    Science.gov (United States)

    Shang, Ronghua; Liu, Huan; Jiao, Licheng

    2017-11-01

    This paper proposes a relatively all-purpose network clustering technique based on the framework of multi-objective evolutionary algorithms, which can effectively dispose the issue of community detection in unsigned social networks, as well as in signed social networks. Firstly, we formulate a generalized similarity function to construct a similarity matrix, and then a pre-partitioning strategy is projected according to the similarity matrix. The pre-partitioning strategy merely considers nodes with high similarity values, which avoids the interference of noise nodes during the label update phase. In this way, at the initial phase of the algorithm, nodes with strong connections are fleetly gathered into sub-communities. Secondly, we elaborately devise a crossover operator, called cross-merging operator, to merge sub-communities generated by the pre-partitioning technique. Moreover, a special mutation operator, based on the similarity matrix of nodes, is implemented to adjust boundary nodes connecting different communities. Finally, to handle different types of networks, we, therefore, have presented the novel multi-objective optimization models for this issue. Through a bulk of rigorous experiments on both unsigned and signed social networks, the preeminent clustering performance illustrate that the proposed algorithm is capable of mining communities effectively.

  7. High Altitude Platforms for Disaster Recovery: Capabilities, Strategies, and Techniques for Providing Emergency Telecommunications

    Energy Technology Data Exchange (ETDEWEB)

    Juan D. Deaton

    2008-05-01

    Natural disasters and terrorist acts have significant potential to disrupt emergency communication systems. These emergency communication networks include first-responder, cellular, landline, and emergency answering services such as 911, 112, or 999. Without these essential emergency communications capabilities, search, rescue, and recovery operations during a catastrophic event will be severely debilitated. High altitude platforms could be fitted with telecommunications equipment and used to support these critical communications missions once the catastrophic event occurs. With the ability to be continuously on station, HAPs provide excellent options for providing emergency coverage over high-risk areas before catastrophic incidents occur. HAPs could also provide enhanced 911 capabilities using either GPS or reference stations. This paper proposes potential emergency communications architecture and presents a method for estimating emergency communications systems traffic patterns for a catastrophic event.

  8. New techniques provide low-cost X-ray inspection of highly attenuating materials

    International Nuclear Information System (INIS)

    Stupin, D.M.; Mueller, K.H.; Viskoe, D.A.; Howard, B.; Poland, R.W.; Schneberk, D.; Dolan, K.; Thompson, K.; Stoker, G.

    1995-01-01

    As a result of an arms reduction treaty between the United States and the Russian Federation, both countries will each be storing over 40,000 containers of plutonium. To help detect any deterioration of the containers and prevent leakage, the authors are designing a digital radiography and computed tomography system capable of handling this volume reliably, efficiently, and at a lower cost. The materials to be stored have very high x-ray attenuations, and, in the past, were inspected using 1- to 24-MV x-ray sources. This inspection system, however, uses a new scintillating (Lockheed) glass and an integrating CCD camera. Preliminary experiments show that this will permit the use of a 450-kV x-ray source. This low-energy system will cost much less than others designed to use a higher-energy x-ray source because it will require a less expensive source, less shielding, and less floor space. Furthermore, they can achieve a tenfold improvement in spatial resolution by using their knowledge of the point-spread function of the x-ray imaging system and a least-squares fitting technique

  9. Evaluation of the Metered-Dose Inhaler Technique among Health Care Providers Practicing in Hamadan University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    E. Nadi

    2004-07-01

    Full Text Available Poor inhaler technique is a common problem both in asthma patients and health care providers , which contributes to poor asthma control. The aim of this study was to evaluate the correctness of metered-dose inhaler (MDI technique in a sample of physicians , pharmacists and nurses practicing in Hamadan University hospitals. A total of 176 healthcare providers (35 internists and general physicians , 138 nurses and 3 pharmacists were participated voluntary in this study. After the participants answered a questionnaire aimed at identifying their involvement in MDI prescribing and counseling , a trained observer assessed their MDI technique using a checklist of ten steps.Of the 176 participants , 35(20% were physician , and 3 subjects (2% were pharmacists , and 138 (78% were nurses. However only 6 participants (3.4% performed all steps correctly. Physicians performed significantly better than non-physicians (8.6% vs. 2.13%.The majority of healthcare providers responsible for instructing patients on the correct MDI technique were unable to perform this technique correctly ‘indicating the need for regular formal training programmes on inhaler techniques.

  10. Protection provided by masks sinkers in interventional techniques; Proteccion ofrecida por mascaras plomadas en tecnicas intervencionistas

    Energy Technology Data Exchange (ETDEWEB)

    Pera Cegarra, O.; Alejo Luque, L.; Pifarre Martinez, J.

    2011-07-01

    The high doses that are taught in laboratories worked indispensable the use of shields and armor. In this context, the use of sinkers glasses is widespread, but not the sinkers of the masks. Our goal is to study the effectiveness of such masks for later comparison with that provided by leaded glasses with side shields. Specifically, compare the reduction in lens dose rate for different positions and orientations of the head of specialist intervention.

  11. Physicochemical, bioactive, and sensory properties of persimmon-based ice cream: technique for order preference by similarity to ideal solution to determine optimum concentration.

    Science.gov (United States)

    Karaman, Safa; Toker, Ömer Said; Yüksel, Ferhat; Çam, Mustafa; Kayacier, Ahmed; Dogan, Mahmut

    2014-01-01

    In the present study, persimmon puree was incorporated into the ice cream mix at different concentrations (8, 16, 24, 32, and 40%) and some physicochemical (dry matter, ash, protein, pH, sugar, fat, mineral, color, and viscosity), textural (hardness, stickiness, and work of penetration), bioactive (antiradical activity and total phenolic content), and sensory properties of samples were investigated. The technique for order preference by similarity to ideal solution approach was used for the determination of optimum persimmon puree concentration based on the sensory and bioactive characteristics of final products. Increase in persimmon puree resulted in a decrease in the dry matter, ash, fat, protein contents, and viscosity of ice cream mix. Glucose, fructose, sucrose, and lactose were determined to be major sugars in the ice cream samples including persimmon and increase in persimmon puree concentration increased the fructose and glucose content. Better melting properties and textural characteristics were observed for the samples with the addition of persimmon. Magnesium, K, and Ca were determined to be major minerals in the samples and only K concentration increased with the increase in persimmon content. Bioactive properties of ice cream samples improved and, in general, acetone-water extracts showed higher bioactivity compared with ones obtained using methanol-water extracts. The technique for order preference by similarity to ideal solution approach showed that the most preferred sample was the ice cream containing 24% persimmon puree. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  12. Effects of moisture content in cigar tobacco on nicotine extraction. Similarity between soxhlet and focused open-vessel microwave-assisted techniques.

    Science.gov (United States)

    Ng, Lay-Keow; Hupé, Michel

    2003-09-05

    The effects of tobacco moisture on nicotine yield were investigated in this study. Soxhlet and microwave-assisted techniques were used to extract nicotine from cigar fillers of varying moisture contents (5-20%), using a polar (methanol) and a non-polar (isooctane) solvent. The extracts were analyzed by a gas chromatograph equipped with a flame-ionization detector. For both extraction techniques, higher nicotine yields were consistently obtained with methanol than with isooctane from the same samples. Solubility of nicotine salts in methanol but not in isooctane is the major cause of this observation. Moreover, pronounced effects of the tobacco moisture content on extraction efficiency were observed with isooctane but not with methanol. For microwave assisted extraction (MAE) with isooctane, nicotine yield increased from 3 to 70% as the moisture level in tobacco was raised from 3 to 13%, and leveled off thereafter. Similar observations were made with Soxhlet extraction. While MAE results were rationalized by the known cell-rupture process, a mechanism based on the interaction between the solvents and the structural components of the plant cells has been proposed to account for the observations made with Soxhlet extraction.

  13. HybridSim-VS: a web server for large-scale ligand-based virtual screening using hybrid similarity recognition techniques.

    Science.gov (United States)

    Shang, Jinling; Dai, Xi; Li, Yecheng; Pistolozzi, Marco; Wang, Ling

    2017-11-01

    Molecular-similarity searches based on two-dimensional (2D) fingerprint and three-dimensional (3D) shape represent two widely used ligand-based virtual screening (VS) methods in computer-aided drug design. 2D fingerprint-based VS utilizes the binary fragment information on a known ligand, whereas 3D shape-based VS takes advantage of geometric information for predefined features from a 3D conformation. Given their different advantages, it would be desirable to hybridize 2D fingerprint and 3D shape molecular-similarity approaches in drug discovery. Here, we presented a general hybrid molecular-similarity protocol, referred to as HybridSim, obtained by combining the 2D fingerprint- and 3D shape-based similarity search methods and evaluated its performance on 595,036 actives and decoys for 40 pharmaceutically relevant targets available in the Directory of Useful Decoys Enhanced (DUD-E). Our results showed that HybridSim significantly improved the overall performance in 40 VS projects as compared with using only 2D fingerprint and 3D shape methods. Furthermore, HybridSim-VS, the first online platform using the proposed HybridSim method coupled with 17,839,945 screenable and purchasable compounds, was developed to provide large-scale and proficient VS capabilities to experts and nonexperts in the field. HybridSim-VS web server is freely available at http://www.rcidm.org/HybridSim-VS/. lingwang@scut.edu.cn. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  14. Could lymphatic mapping and sentinel node biopsy provide oncological providence for local resectional techniques for colon cancer? A review of the literature

    Directory of Open Access Journals (Sweden)

    Leroy Joel

    2008-09-01

    Full Text Available Abstract Background Endoscopic resectional techniques for colon cancer are undermined by their inability to determine lymph node status. This limits their application to only those lesions at the most minimal risk of lymphatic dissemination whereas their technical capacity could allow intraluminal or even transluminal address of larger lesions. Sentinel node biopsy may theoretically address this breach although the variability of its reported results for this disease is worrisome. Methods Medline, EMBASE and Cochrane databases were interrogated back to 1999 to identify all publications concerning lymphatic mapping for colon cancer with reference cross-checking for completeness. All reports were examined from the perspective of in vivo technique accuracy selectively in early stage disease (i.e. lesions potentially within the technical capacity of endoscopic resection. Results Fifty-two studies detailing the experiences of 3390 patients were identified. Considerable variation in patient characteristics as well as in surgical and histological quality assurances were however evident among the studies identified. In addition, considerable contamination of the studies by inclusion of rectal cancer without subgroup separation was frequent. Indeed such is the heterogeneity of the publications to date, formal meta-analysis to pool patient cohorts in order to definitively ascertain technique accuracy in those with T1 and/or T2 cancer is not possible. Although lymphatic mapping in early stage neoplasia alone has rarely been specifically studied, those studies that included examination of false negative rates identified high T3/4 patient proportions and larger tumor size as being important confounders. Under selected circumstances however the technique seems to perform sufficiently reliably to allow it prompt consideration of its use to tailor operative extent. Conclusion The specific question of whether sentinel node biopsy can augment the oncological

  15. PEMILIHAN STRATEGI PEMASARAN DI KAMPOENG KOPI BANARAN MENGGUNAKAN PENDEKATAN METODE ANALYTICAL NETWORK PROCESS (ANP DAN TECHNIQUE FOR ORDER PREFERENCE BY SIMILARITY TO AN IDEAL SOLUTION (TOPSIS

    Directory of Open Access Journals (Sweden)

    Aries Susanty

    2014-09-01

    Full Text Available Kampoeng Kopi Banaran belum dapat mencapai laba sesuai dengan target yang telah ditetapkan. Diduga hal ini terjadi karena semakin banyaknya pesaing dengan usaha sejenis, seperti Cimory, Kampoeng Rawa, Tlogo Plantation, Salib Putih, dan Umbul Sidomukti serta belum dimilikinya strategi pemasaran yang tepat oleh Kampoeng Kopi Banaran. Selama ini, Kampoeng Kopi Banaran baru memasarkan  produk-produk yang dimilikinya dengan menggunakan website, brosur,  dan promosi mulut ke mulut.  Berdasarkan hal tersebut, penelitian ini bertujuan untuk  mengidentifikasi kriteria dan subkriteria yang tepat bagi penyusunan strategi pemasaran dari Kampoeng Kopi Banaran, menentukan bobot dari setiap kriteria dan subkriteria tersebut, serta mengusulkan strategi pemasaran tertentu berdasarkan kriteria dan subkriteria tersebut. Dalam penelitian ini, terdapat delapan buah kriteria yang digunakan sebagai dasar untuk menyusun strategi pemasaran bagi Kampoeng Kopi Banaran, yaitu Managerial Capabilities (MC, Market Innovation Capabilities (MIC, Customer Linking Capabilities (CLC, Human Resource Assetes (HRA, Reputational Asset (RA, Competition (C, Economy (E, dan Social and cultural (SC. Selanjutnya kedelapan kriteria tersebut akan dijabarkan lagi menjadi sejumlah subkriteria. Metoda yang digunakan untuk menghitung bobot dari kriteria dan subkriteria adalah Analitycal Network Process (ANP; sedangkan metoda yang digunakan untuk penyusunan strategi pemasaran adalah  Technique for Others Reference by Similarity to Ideal Solution (TOPSIS . Data untuk penelitian ini diperoleh dengan melakukan penyebaran kuesioner kepada manager dan bagian marketing Kampoeng Kopi Banaran. Hasil pengolahan data menunjukkan kriteria yang memiliki bobot tertinggi untuk penyusunan strategi pemasaran di Kampoeng Kopi Banaran adalah Managerial Capabilities (MC (0,1897 dan sub kriteria yagn memiliki bobot tertinggi adalah subkriteria brand atau reputasi (0,1277. Selanjutnya, strategi yang terbaik

  16. Outsourced similarity search on metric data assets

    KAUST Repository

    Yiu, Man Lung

    2012-02-01

    This paper considers a cloud computing setting in which similarity querying of metric data is outsourced to a service provider. The data is to be revealed only to trusted users, not to the service provider or anyone else. Users query the server for the most similar data objects to a query example. Outsourcing offers the data owner scalability and a low-initial investment. The need for privacy may be due to the data being sensitive (e.g., in medicine), valuable (e.g., in astronomy), or otherwise confidential. Given this setting, the paper presents techniques that transform the data prior to supplying it to the service provider for similarity queries on the transformed data. Our techniques provide interesting trade-offs between query cost and accuracy. They are then further extended to offer an intuitive privacy guarantee. Empirical studies with real data demonstrate that the techniques are capable of offering privacy while enabling efficient and accurate processing of similarity queries.

  17. Is pelvic fixation the only option to provide additional stability to the sacral anchorage in long lumbar instrumentation? A comparative biomechanical study of new techniques.

    Science.gov (United States)

    Volkheimer, David; Reichel, Heiko; Wilke, Hans-Joachim; Lattig, Friederike

    2017-03-01

    Supplementary iliac screws have the highest potential to protect S1-pedicle-screws from loosening in long fusion constructs. However, this technique bridges the iliosacral joint with potential disadvantages for the patient. This study aimed to evaluate if two different established fixation techniques can be used in addition to pedicle screws as alternative to iliac screws, and if these two techniques can provide similar stability when S1-pedicle-screws are loosened. Flexibility testing with pure moments of 7.5Nm was performed with six human osteopenic/osteoporotic L4-pelvis specimens. The following conditions were investigated: 1. Intact; 2. Destabilization L5/S1; 3. Fixation with rigid L4-S1 pedicle-screw-system; 4. Condition 3- loosening of S1-screws; 5. Condition 4- L5-S2-lamina-hooks; 6. Condition 4- L5/S1-translaminar-screws; 7. Condition 4- S2-ala-ilium screws. Application of compressive L5-S2-lamina-hooks or L5/S1-translaminar-screws next to pedicle screws in L5 and S1 was feasible in all specimens. L4-S1-pedicle-screw-instrumentation reduced the Range of Motion significantly compared to the destabilized condition. After simulation of S1 screw loosening, lamina hooks only reduced the Range of Motion in flexion/extension significantly. L5/S1-translaminar-screws had a higher stabilizing effect in lateral bending and axial rotation, but the effect of both systems was smaller than with an instrumentation extension to the os ilium. In long lumbar pedicle screw instrumentations including L5/S1, additional ilium screws have the highest potential to protect the S1-anchorage. Additional L5/S1-translaminar-screws can increase stability of the lumbosacral junction without bridging the iliosacral joint, whereas lamina hooks showed no significant biomechanical benefit. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Unmixing of spectrally similar minerals

    CSIR Research Space (South Africa)

    Debba, Pravesh

    2009-01-01

    Full Text Available techniques is complicated when considering very similar spectral signatures. Iron-bearing oxide/hydroxide/sulfate minerals have similar spectral signatures. The study focuses on how could estimates of abundances of spectrally similar iron-bearing oxide...

  19. Systematic review: what surgical technique provides the best outcome for symptomatic partial articular-sided rotator cuff tears?

    Science.gov (United States)

    Bollier, Matthew; Shea, Kevin

    2012-01-01

    -open repair. Improved long-term results and decreased reoperation rates were reported in the tear completion and repair group. On the basis of the available evidence, no single technique provides superior clinical outcomes. Level I and II comparison studies are needed to determine the optimal treatment of partial articular-sided rotator cuff tears.

  20. Dimensionality Reduction Using Similarity-Induced Embeddings.

    Science.gov (United States)

    Passalis, Nikolaos; Tefas, Anastasios

    2017-08-08

    The vast majority of dimensionality reduction (DR) techniques rely on the second-order statistics to define their optimization objective. Even though this provides adequate results in most cases, it comes with several shortcomings. The methods require carefully designed regularizers and they are usually prone to outliers. In this paper, a new DR framework that can directly model the target distribution using the notion of similarity instead of distance is introduced. The proposed framework, called similarity embedding framework (SEF), can overcome the aforementioned limitations and provides a conceptually simpler way to express optimization targets similar to existing DR techniques. Deriving a new DR technique using the SEF becomes simply a matter of choosing an appropriate target similarity matrix. A variety of classical tasks, such as performing supervised DR and providing out-of-sample extensions, as well as, new novel techniques, such as providing fast linear embeddings for complex techniques, are demonstrated in this paper using the proposed framework. Six data sets from a diverse range of domains are used to evaluate the proposed method and it is demonstrated that it can outperform many existing DR techniques.

  1. Using data mining techniques to explore physicians' therapeutic decisions when clinical guidelines do not provide recommendations: methods and example for type 2 diabetes.

    Science.gov (United States)

    Toussi, Massoud; Lamy, Jean-Baptiste; Le Toumelin, Philippe; Venot, Alain

    2009-06-10

    Clinical guidelines carry medical evidence to the point of practice. As evidence is not always available, many guidelines do not provide recommendations for all clinical situations encountered in practice. We propose an approach for identifying knowledge gaps in guidelines and for exploring physicians' therapeutic decisions with data mining techniques to fill these knowledge gaps. We demonstrate our method by an example in the domain of type 2 diabetes. We analyzed the French national guidelines for the management of type 2 diabetes to identify clinical conditions that are not covered or those for which the guidelines do not provide recommendations. We extracted patient records corresponding to each clinical condition from a database of type 2 diabetic patients treated at Avicenne University Hospital of Bobigny, France. We explored physicians' prescriptions for each of these profiles using C5.0 decision-tree learning algorithm. We developed decision-trees for different levels of detail of the therapeutic decision, namely the type of treatment, the pharmaco-therapeutic class, the international non proprietary name, and the dose of each medication. We compared the rules generated with those added to the guidelines in a newer version, to examine their similarity. We extracted 27 rules from the analysis of a database of 463 patient records. Eleven rules were about the choice of the type of treatment and thirteen rules about the choice of the pharmaco-therapeutic class of each drug. For the choice of the international non proprietary name and the dose, we could extract only a few rules because the number of patient records was too low for these factors. The extracted rules showed similarities with those added to the newer version of the guidelines. Our method showed its usefulness for completing guidelines recommendations with rules learnt automatically from physicians' prescriptions. It could be used during the development of guidelines as a complementary source from

  2. Using data mining techniques to explore physicians' therapeutic decisions when clinical guidelines do not provide recommendations: methods and example for type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Toussi Massoud

    2009-06-01

    Full Text Available Abstract Background Clinical guidelines carry medical evidence to the point of practice. As evidence is not always available, many guidelines do not provide recommendations for all clinical situations encountered in practice. We propose an approach for identifying knowledge gaps in guidelines and for exploring physicians' therapeutic decisions with data mining techniques to fill these knowledge gaps. We demonstrate our method by an example in the domain of type 2 diabetes. Methods We analyzed the French national guidelines for the management of type 2 diabetes to identify clinical conditions that are not covered or those for which the guidelines do not provide recommendations. We extracted patient records corresponding to each clinical condition from a database of type 2 diabetic patients treated at Avicenne University Hospital of Bobigny, France. We explored physicians' prescriptions for each of these profiles using C5.0 decision-tree learning algorithm. We developed decision-trees for different levels of detail of the therapeutic decision, namely the type of treatment, the pharmaco-therapeutic class, the international non proprietary name, and the dose of each medication. We compared the rules generated with those added to the guidelines in a newer version, to examine their similarity. Results We extracted 27 rules from the analysis of a database of 463 patient records. Eleven rules were about the choice of the type of treatment and thirteen rules about the choice of the pharmaco-therapeutic class of each drug. For the choice of the international non proprietary name and the dose, we could extract only a few rules because the number of patient records was too low for these factors. The extracted rules showed similarities with those added to the newer version of the guidelines. Conclusion Our method showed its usefulness for completing guidelines recommendations with rules learnt automatically from physicians' prescriptions. It could be used

  3. Judgments of brand similarity

    NARCIS (Netherlands)

    Bijmolt, THA; Wedel, M; Pieters, RGM; DeSarbo, WS

    This paper provides empirical insight into the way consumers make pairwise similarity judgments between brands, and how familiarity with the brands, serial position of the pair in a sequence, and the presentation format affect these judgments. Within the similarity judgment process both the

  4. Minimally Invasive Endourological Techniques may Provide a Novel Method for Relieving Urinary Obstruction due to Ureterosciatic Herniation

    Science.gov (United States)

    Kato, Tomonori; Komiya, Akira; Ikeda, Ryoichi; Nakamura, Takeshi; Akakura, Koichiro

    2015-01-01

    Ureterosciatic herniation, the protrusion of the hernia sac through the sciatic foramen, is an extremely rare cause of ureteral obstruction. We describe a case revealed by severe left back pain in a 72-year-old female. She was referred to our hospital for urological assessment of left hydronephrosis observed by ultrasonography. Intravenous ureterography (IVU) showed findings compatible with a left sciatic ureter, a dilated ureter with a fixed kinking, which is known as the ‘curlicue’ sign. We decided to attempt recovery of the herniated ureter using a retrograde approach. Ureteral stent placement was performed to decompress the dilated upper urinary tract. The ureterosciatic hernia was relieved with the passage of a flexible guide wire and a double-pigtail stent. Three months after ureteral stenting, she refused continuing to have an indwelling stent and the stent was removed. Thereafter, IVU revealed recurrent ureterosciatic hernia; however, there was no hydroureter or hydronephrosis. The patient is currently being under observation for 6 years after stenting and continues to be without hydronephrosis or symptoms. Placement of an internal stent possibly provides the rigidity to the ureter, thereby reducing the hernia and urinary obstruction. In the previous reports, most symptomatic patients have been treated surgically, with conservative therapy reserved for asymptomatic patients. For the patient who is elderly or a poor surgical candidate, retrograde stenting may provide safe reduction and efficacious treatment. This endourological approach provides a minimally invasive means for the management of urinary obstruction caused by ureterosciatic herniation. PMID:25849669

  5. Genome-wide comparative analysis reveals similar types of NBS genes in hybrid Citrus sinensis genome and original Citrus clementine genome and provides new insights into non-TIR NBS genes.

    Directory of Open Access Journals (Sweden)

    Yunsheng Wang

    Full Text Available In this study, we identified and compared nucleotide-binding site (NBS domain-containing genes from three Citrus genomes (C. clementina, C. sinensis from USA and C. sinensis from China. Phylogenetic analysis of all Citrus NBS genes across these three genomes revealed that there are three approximately evenly numbered groups: one group contains the Toll-Interleukin receptor (TIR domain and two different Non-TIR groups in which most of proteins contain the Coiled Coil (CC domain. Motif analysis confirmed that the two groups of CC-containing NBS genes are from different evolutionary origins. We partitioned NBS genes into clades using NBS domain sequence distances and found most clades include NBS genes from all three Citrus genomes. This suggests that three Citrus genomes have similar numbers and types of NBS genes. We also mapped the re-sequenced reads of three pomelo and three mandarin genomes onto the C. sinensis genome. We found that most NBS genes of the hybrid C. sinensis genome have corresponding homologous genes in both pomelo and mandarin genomes. The homologous NBS genes in pomelo and mandarin suggest that the parental species of C. sinensis may contain similar types of NBS genes. This explains why the hybrid C. sinensis and original C. clementina have similar types of NBS genes in this study. Furthermore, we found that sequence variation amongst Citrus NBS genes were shaped by multiple independent and shared accelerated mutation accumulation events among different groups of NBS genes and in different Citrus genomes. Our comparative analyses yield valuable insight into the structure, organization and evolution of NBS genes in Citrus genomes. Furthermore, our comprehensive analysis showed that the non-TIR NBS genes can be divided into two groups that come from different evolutionary origins. This provides new insights into non-TIR genes, which have not received much attention.

  6. Intraclass reliability for assessing how well Taiwan constrained hospital-provided medical services using statistical process control chart techniques

    Directory of Open Access Journals (Sweden)

    Chien Tsair-Wei

    2012-05-01

    Full Text Available Abstract Background Few studies discuss the indicators used to assess the effect on cost containment in healthcare across hospitals in a single-payer national healthcare system with constrained medical resources. We present the intraclass correlation coefficient (ICC to assess how well Taiwan constrained hospital-provided medical services in such a system. Methods A custom Excel-VBA routine to record the distances of standard deviations (SDs from the central line (the mean over the previous 12 months of a control chart was used to construct and scale annual medical expenditures sequentially from 2000 to 2009 for 421 hospitals in Taiwan to generate the ICC. The ICC was then used to evaluate Taiwan’s year-based convergent power to remain unchanged in hospital-provided constrained medical services. A bubble chart of SDs for a specific month was generated to present the effects of using control charts in a national healthcare system. Results ICCs were generated for Taiwan’s year-based convergent power to constrain its medical services from 2000 to 2009. All hospital groups showed a gradually well-controlled supply of services that decreased from 0.772 to 0.415. The bubble chart identified outlier hospitals that required investigation of possible excessive reimbursements in a specific time period. Conclusion We recommend using the ICC to annually assess a nation’s year-based convergent power to constrain medical services across hospitals. Using sequential control charts to regularly monitor hospital reimbursements is required to achieve financial control in a single-payer nationwide healthcare system.

  7. Total arsenic concentrations in toenails quantified by two techniques provide a useful biomarker of chronic arsenic exposure in drinking water

    International Nuclear Information System (INIS)

    Adair, Blakely M.; Hudgens, Edward E.; Schmitt, Michael T.; Calderon, Rebecca L.; Thomas, David J.

    2006-01-01

    Accurate quantitation of any contaminant of interest is critical for exposure assessment and metabolism studies that support risk assessment. A preliminary step in an arsenic exposure assessment study in Nevada quantified total arsenic (TAs) concentrations in tissues as biomarkers of exposure. Participants in this study (n=95) were at least 45 years old, had lived in the area for more than 20 years, and were exposed to a wide range of arsenic concentrations in drinking water (3-2100ppb). Concentrations of TAs in blood, urine, and toenails determined by hydride generation-atomic fluorescence spectrometry (HG-AFS) ranged from below detection to 0.03, 0.76, and 12ppm, respectively; TAs in blood rarely exceeded the limit of detection. For comparison, TAs in toenails determined by neutron activation analysis (NAA) ranged from below detection to 16ppm. Significant (P 2 =0.3557 HG-AFS, adjusted r 2 =0.3922 NAA); TAs concentrations in urine were not described by drinking water As (adjusted r 2 =0.0170, P=0.1369). Analyses of TAs in toenails by HGAFS and NAA yielded highly concordant estimates (r=0.7977, P<0.0001). These results suggest that toenails are a better biomarker of chronic As exposure than urine in the current study, because the sequestration of As in toenails provides an integration of exposure over time that does not occur in urine

  8. Conversion technique from paper-based seismic profiles to SEG-Y degital data, provided by free softwares

    Science.gov (United States)

    Tuzino, Taqumi

    This article introduces a conversion method from paper-based seismic profiles to SEG-Y formatted degital data. This method employs two free software, NetPBM and Seismic Unix which work on Unix-like OS. The principle is 1) scanning paper-based profiles to obtain pixel images conposed of 8 bit charactor, 2) conversion of trace data format from character to floating and 3) paste of SEG-Y header to floating trace data. Paper-based profiles drown by line scan recorder were successfully converted to trace-by-pixel SEG-Y data. Paper based wiggle profiles were converted firstly to trace-by-pixel SEG-Y data, and then to trace-by-trace SEG-Y data, by using horizontal trace sum of trace-by-pixel data. Quality of these data was examined and proofed that they are tolerable to be used, though they have restriction of paper. SEG-Y convertied data would provide additional analyses; deconvolution, migration, seismic attribute analyses, and would be ready for interpretation softwares.

  9. The Turn the Tables Technique (T[cube]): A Program Activity to Provide Group Facilitators Insight into Teen Sexual Behaviors and Beliefs

    Science.gov (United States)

    Sclafane, Jamie Heather; Merves, Marni Loiacono; Rivera, Angelic; Long, Laura; Wilson, Ken; Bauman, Laurie J.

    2012-01-01

    The Turn the Tables Technique (T[cube]) is an activity designed to provide group facilitators who lead HIV/STI prevention and sexual health promotion programs with detailed and current information on teenagers' sexual behaviors and beliefs. This information can be used throughout a program to tailor content. Included is a detailed lesson plan of…

  10. The semantic similarity ensemble

    Directory of Open Access Journals (Sweden)

    Andrea Ballatore

    2013-12-01

    Full Text Available Computational measures of semantic similarity between geographic terms provide valuable support across geographic information retrieval, data mining, and information integration. To date, a wide variety of approaches to geo-semantic similarity have been devised. A judgment of similarity is not intrinsically right or wrong, but obtains a certain degree of cognitive plausibility, depending on how closely it mimics human behavior. Thus selecting the most appropriate measure for a specific task is a significant challenge. To address this issue, we make an analogy between computational similarity measures and soliciting domain expert opinions, which incorporate a subjective set of beliefs, perceptions, hypotheses, and epistemic biases. Following this analogy, we define the semantic similarity ensemble (SSE as a composition of different similarity measures, acting as a panel of experts having to reach a decision on the semantic similarity of a set of geographic terms. The approach is evaluated in comparison to human judgments, and results indicate that an SSE performs better than the average of its parts. Although the best member tends to outperform the ensemble, all ensembles outperform the average performance of each ensemble's member. Hence, in contexts where the best measure is unknown, the ensemble provides a more cognitively plausible approach.

  11. Similarity Measure of Graphs

    Directory of Open Access Journals (Sweden)

    Amine Labriji

    2017-07-01

    Full Text Available The topic of identifying the similarity of graphs was considered as highly recommended research field in the Web semantic, artificial intelligence, the shape recognition and information research. One of the fundamental problems of graph databases is finding similar graphs to a graph query. Existing approaches dealing with this problem are usually based on the nodes and arcs of the two graphs, regardless of parental semantic links. For instance, a common connection is not identified as being part of the similarity of two graphs in cases like two graphs without common concepts, the measure of similarity based on the union of two graphs, or the one based on the notion of maximum common sub-graph (SCM, or the distance of edition of graphs. This leads to an inadequate situation in the context of information research. To overcome this problem, we suggest a new measure of similarity between graphs, based on the similarity measure of Wu and Palmer. We have shown that this new measure satisfies the properties of a measure of similarities and we applied this new measure on examples. The results show that our measure provides a run time with a gain of time compared to existing approaches. In addition, we compared the relevance of the similarity values obtained, it appears that this new graphs measure is advantageous and  offers a contribution to solving the problem mentioned above.

  12. Selective Thoracic Fusion Provides Similar Health-Related Quality of Life but Can Cause More Lumbar Disc and Facet Joint Degeneration: A Comparison of Adolescent Idiopathic Scoliosis Patients With Normal Population 10 Years After Surgery.

    Science.gov (United States)

    Enercan, Meric; Kahraman, Sinan; Cobanoglu, Mutlu; Yilar, Sinan; Gokcen, Bahadir Huseyin; Karadereler, Selhan; Mutlu, Ayhan; Ulusoy, Levent Onur; Ozturk, Cagatay; Erturer, Erden; Gebes, Elif; Sanli, Tunay; Alanay, Ahmet; Hamzaoglu, Azmi

    2015-09-01

    To evaluate the long-term behavior of the lumbar curve in patients with adolescent idiopathic scoliosis treated with selective thoracic fusion and to assess the clinical and radiologic outcomes in this fusion group compared with an age- and gender-matched group. Selective thoracic fusion for the treatment of adolescent idiopathic scoliosis (AIS) preserves lumbar motion segments but leaves a residual deformity. By avoiding fusion of the lumbar spine, a greater mobility may be preserved, which may be an advantage in long-term follow-up in terms of degenerative changes in unfused segments. Group A included 25 AIS patients with mean a age of 23.8 years and a mean 11.4 years of follow-up. Group B included 30 age- and gender-matched subjects without any deformity. Preoperative, postoperative, and follow-up radiographs were reviewed. All patients had MRIs taken at the final follow-up in order to evaluate disc degeneration (DD) and facet joint degeneration (FJD) at the unfused lumbar spine. Clinical evaluation was done by using Scoliosis Research Society-22R, Oswestry Disability Index, and numerical rating scale. Sagittal and coronal balance and lowest instrumented vertebra disc angulation were stable over time. Mean grading of lumbar DD was 2.16 (2-4) in Group A and 1.86 (1-3) in Group B. Lumbar FJDs were 2.05 (1-4) in Group A and 1.60 (1-3) in Group B. There was significant difference between the two groups for DD except for the L4-L5 level (p = .26). FJD was significantly higher in the L1-L2 and L2-L3 levels (L1-L2, p = .002, L2-L3, p = .002) but not for the other levels. Outcome scores were similar without significant differences between the two groups (p > .05). Selective thoracic fusion provides satisfactory outcomes at more than 10 years of follow-up. Our study demonstrated a moderate increase in the rate of disc degeneration in the unfused segments. Facet joint degeneration was significant at the upper two levels adjacent to the lowest instrumented vertebra

  13. Similarity measures for protein ensembles

    DEFF Research Database (Denmark)

    Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper

    2009-01-01

    Analyses of similarities and changes in protein conformation can provide important information regarding protein function and evolution. Many scores, including the commonly used root mean square deviation, have therefore been developed to quantify the similarities of different protein conformatio...

  14. Similarity measures for protein ensembles

    DEFF Research Database (Denmark)

    Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper

    2009-01-01

    Analyses of similarities and changes in protein conformation can provide important information regarding protein function and evolution. Many scores, including the commonly used root mean square deviation, have therefore been developed to quantify the similarities of different protein conformations...

  15. Using nominal group technique among clinical providers to identify barriers and prioritize solutions to scaling up opioid agonist therapies in Ukraine.

    Science.gov (United States)

    Madden, Lynn; Bojko, Martha J; Farnum, Scott; Mazhnaya, Alyona; Fomenko, Tatiana; Marcus, Ruthanne; Barry, Declan; Ivanchuk, Irina; Kolomiets, Viktor; Filippovych, Sergey; Dvoryak, Sergey; Altice, Frederick L

    2017-11-01

    Opioid agonist therapies (OAT) like methadone and buprenorphine maintenance treatment remain markedly under-scaled in Ukraine despite adequate funding. Clinicians and administrators were assembled as part of an implementation science strategy to scale-up OAT using the Network for Improvement of Addiction Treatment (NIATx) approach. Nominal Group Technique (NGT), a key ingredient of the NIATx toolkit, was directed by three trained coaches within a learning collaborative of 18 OAT clinicians and administrators to identify barriers to increase OAT capacity at the regional "oblast" level, develop solutions, and prioritize local change projects. NGT findings were supplemented from detailed notes collected during the NGT discussion. The top three identified barriers included: (1) Strict regulations and inflexible policies dictating distribution and dispensing of OAT; (2) No systematic approach to assessing OAT needs on regional or local level; and (3) Limited funding and financing mechanisms combined with a lack of local/regional control over funding for OAT treatment services. NGT provides a rapid strategy for individuals at multiple levels to work collaboratively to identify and address structural barriers to OAT scale-up. This technique creates a transparent process to address and prioritize complex issues. Targeting these priorities allowed leaders at the regional and national level to advocate collectively for approaches to minimize obstacles and create policies to improve OAT services. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Intraoperative radiation therapy in patients with bladder cancer. A review of techniques allowing improved tumor doses and providing high cure rates without loss of bladder function

    International Nuclear Information System (INIS)

    Shipley, W.U.; Kaufman, S.D.; Prout, G.R. Jr.

    1987-01-01

    Conventional external beam irradiation, using modern megavoltage techniques and doses that do not harm bladder function, will permanently eradicate local bladder cancer in 30% to 50% of patients, compared with 70% to 90% with cystectomy. In appropriately chosen patients, open surgery can safely provide excellent exposure for the selective delivery of more radiant energy directly to the tumor and less to the uninvolved portion of the bladder. Intraoperative radiation therapy, by either a removable radium or iridium implant or a large single dose of electrons, has been reported to be safe and can permanently cure the bladder of cancer and also preserve bladder function in more than 75% of patients with solitary tumors that invade into but not beyond the bladder muscle. With the increasing interest in and availability of intraoperative radiation therapy in the US, this curative and bladder-sparing treatment for operable patients with bladder cancer invading the trigone is appropriate for careful clinical trial. 13 references

  17. Dimensionality Reduction using Similarity-induced Embeddings

    OpenAIRE

    Passalis, Nikolaos; Tefas, Anastasios

    2017-01-01

    The vast majority of Dimensionality Reduction (DR) techniques rely on second-order statistics to define their optimization objective. Even though this provides adequate results in most cases, it comes with several shortcomings. The methods require carefully designed regularizers and they are usually prone to outliers. In this work, a new DR framework, that can directly model the target distribution using the notion of similarity instead of distance, is introduced. The proposed framework, call...

  18. Parallel trajectory similarity joins in spatial networks

    KAUST Repository

    Shang, Shuo

    2018-04-04

    The matching of similar pairs of objects, called similarity join, is fundamental functionality in data management. We consider two cases of trajectory similarity joins (TS-Joins), including a threshold-based join (Tb-TS-Join) and a top-k TS-Join (k-TS-Join), where the objects are trajectories of vehicles moving in road networks. Given two sets of trajectories and a threshold θ, the Tb-TS-Join returns all pairs of trajectories from the two sets with similarity above θ. In contrast, the k-TS-Join does not take a threshold as a parameter, and it returns the top-k most similar trajectory pairs from the two sets. The TS-Joins target diverse applications such as trajectory near-duplicate detection, data cleaning, ridesharing recommendation, and traffic congestion prediction. With these applications in mind, we provide purposeful definitions of similarity. To enable efficient processing of the TS-Joins on large sets of trajectories, we develop search space pruning techniques and enable use of the parallel processing capabilities of modern processors. Specifically, we present a two-phase divide-and-conquer search framework that lays the foundation for the algorithms for the Tb-TS-Join and the k-TS-Join that rely on different pruning techniques to achieve efficiency. For each trajectory, the algorithms first find similar trajectories. Then they merge the results to obtain the final result. The algorithms for the two joins exploit different upper and lower bounds on the spatiotemporal trajectory similarity and different heuristic scheduling strategies for search space pruning. Their per-trajectory searches are independent of each other and can be performed in parallel, and the mergings have constant cost. An empirical study with real data offers insight in the performance of the algorithms and demonstrates that they are capable of outperforming well-designed baseline algorithms by an order of magnitude.

  19. Trajectory similarity join in spatial networks

    KAUST Repository

    Shang, Shuo

    2017-09-07

    The matching of similar pairs of objects, called similarity join, is fundamental functionality in data management. We consider the case of trajectory similarity join (TS-Join), where the objects are trajectories of vehicles moving in road networks. Thus, given two sets of trajectories and a threshold θ, the TS-Join returns all pairs of trajectories from the two sets with similarity above θ. This join targets applications such as trajectory near-duplicate detection, data cleaning, ridesharing recommendation, and traffic congestion prediction. With these applications in mind, we provide a purposeful definition of similarity. To enable efficient TS-Join processing on large sets of trajectories, we develop search space pruning techniques and take into account the parallel processing capabilities of modern processors. Specifically, we present a two-phase divide-and-conquer algorithm. For each trajectory, the algorithm first finds similar trajectories. Then it merges the results to achieve a final result. The algorithm exploits an upper bound on the spatiotemporal similarity and a heuristic scheduling strategy for search space pruning. The algorithm\\'s per-trajectory searches are independent of each other and can be performed in parallel, and the merging has constant cost. An empirical study with real data offers insight in the performance of the algorithm and demonstrates that is capable of outperforming a well-designed baseline algorithm by an order of magnitude.

  20. Skill (or lack thereof of data-model fusion techniques to provide an early warning signal for an approaching tipping point.

    Directory of Open Access Journals (Sweden)

    Riddhi Singh

    Full Text Available Many coupled human-natural systems have the potential to exhibit a highly nonlinear threshold response to external forcings resulting in fast transitions to undesirable states (such as eutrophication in a lake. Often, there are considerable uncertainties that make identifying the threshold challenging. Thus, rapid learning is critical for guiding management actions to avoid abrupt transitions. Here, we adopt the shallow lake problem as a test case to compare the performance of four common data assimilation schemes to predict an approaching transition. In order to demonstrate the complex interactions between management strategies and the ability of the data assimilation schemes to predict eutrophication, we also analyze our results across two different management strategies governing phosphorus emissions into the shallow lake. The compared data assimilation schemes are: ensemble Kalman filtering (EnKF, particle filtering (PF, pre-calibration (PC, and Markov Chain Monte Carlo (MCMC estimation. While differing in their core assumptions, each data assimilation scheme is based on Bayes' theorem and updates prior beliefs about a system based on new information. For large computational investments, EnKF, PF and MCMC show similar skill in capturing the observed phosphorus in the lake (measured as expected root mean squared prediction error. EnKF, followed by PF, displays the highest learning rates at low computational cost, thus providing a more reliable signal of an impending transition. MCMC approaches the true probability of eutrophication only after a strong signal of an impending transition emerges from the observations. Overall, we find that learning rates are greatest near regions of abrupt transitions, posing a challenge to early learning and preemptive management of systems with such abrupt transitions.

  1. Semantic Similarity between Web Documents Using Ontology

    Science.gov (United States)

    Chahal, Poonam; Singh Tomer, Manjeet; Kumar, Suresh

    2018-03-01

    The World Wide Web is the source of information available in the structure of interlinked web pages. However, the procedure of extracting significant information with the assistance of search engine is incredibly critical. This is for the reason that web information is written mainly by using natural language, and further available to individual human. Several efforts have been made in semantic similarity computation between documents using words, concepts and concepts relationship but still the outcome available are not as per the user requirements. This paper proposes a novel technique for computation of semantic similarity between documents that not only takes concepts available in documents but also relationships that are available between the concepts. In our approach documents are being processed by making ontology of the documents using base ontology and a dictionary containing concepts records. Each such record is made up of the probable words which represents a given concept. Finally, document ontology's are compared to find their semantic similarity by taking the relationships among concepts. Relevant concepts and relations between the concepts have been explored by capturing author and user intention. The proposed semantic analysis technique provides improved results as compared to the existing techniques.

  2. Similarity transformations of MAPs

    Directory of Open Access Journals (Sweden)

    Andersen Allan T.

    1999-01-01

    Full Text Available We introduce the notion of similar Markovian Arrival Processes (MAPs and show that the event stationary point processes related to two similar MAPs are stochastically equivalent. This holds true for the time stationary point processes too. We show that several well known stochastical equivalences as e.g. that between the H 2 renewal process and the Interrupted Poisson Process (IPP can be expressed by the similarity transformations of MAPs. In the appendix the valid region of similarity transformations for two-state MAPs is characterized.

  3. Can intubation harm the brain in critical care situations? A new simple technique may provide a method for controlling brain temperature

    DEFF Research Database (Denmark)

    Einer-Jensen, N.; Baptiste, K.E.; Madsen, F.

    2002-01-01

    to previous values when the oxygen flushing was stopped. Cooling was found in animals with a rete a similar cooling mechanism is present in man (no rete) under mirabile (pigs), and in animals without a rete (rats). intensive care, a simple flushing of the nasal cavities with gas will protect the brain against...

  4. Privacy-preserving matching of similar patients.

    Science.gov (United States)

    Vatsalan, Dinusha; Christen, Peter

    2016-02-01

    The identification of similar entities represented by records in different databases has drawn considerable attention in many application areas, including in the health domain. One important type of entity matching application that is vital for quality healthcare analytics is the identification of similar patients, known as similar patient matching. A key component of identifying similar records is the calculation of similarity of the values in attributes (fields) between these records. Due to increasing privacy and confidentiality concerns, using the actual attribute values of patient records to identify similar records across different organizations is becoming non-trivial because the attributes in such records often contain highly sensitive information such as personal and medical details of patients. Therefore, the matching needs to be based on masked (encoded) values while being effective and efficient to allow matching of large databases. Bloom filter encoding has widely been used as an efficient masking technique for privacy-preserving matching of string and categorical values. However, no work on Bloom filter-based masking of numerical data, such as integer (e.g. age), floating point (e.g. body mass index), and modulus (numbers wrap around upon reaching a certain value, e.g. date and time), which are commonly required in the health domain, has been presented in the literature. We propose a framework with novel methods for masking numerical data using Bloom filters, thereby facilitating the calculation of similarities between records. We conduct an empirical study on publicly available real-world datasets which shows that our framework provides efficient masking and achieves similar matching accuracy compared to the matching of actual unencoded patient records. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. New Similarity Functions

    DEFF Research Database (Denmark)

    Yazdani, Hossein; Ortiz-Arroyo, Daniel; Kwasnicka, Halina

    2016-01-01

    In data science, there are important parameters that affect the accuracy of the algorithms used. Some of these parameters are: the type of data objects, the membership assignments, and distance or similarity functions. This paper discusses similarity functions as fundamental elements in membership...

  6. Similarity after Goodman

    NARCIS (Netherlands)

    Decock, L.B.; Douven, I.

    2011-01-01

    In a famous critique, Goodman dismissed similarity as a slippery and both philosophically and scientifically useless notion. We revisit his critique in the light of important recent work on similarity in psychology and cognitive science. Specifically, we use Tversky's influential set-theoretic

  7. Use of multiple attributes decision-making Technique for Order Preference by Similarity to Ideal Solution (TOPSIS for Ghare-Gheshlagh calcite in determination of optimum geochemical sampling sites

    Directory of Open Access Journals (Sweden)

    Mansour Rezaei Azizi

    2015-04-01

    for green, white and pink calcites were varied 0.087, 0.247 and 0.997 respectively. The low amounts of Eu anomaly for green and white calcites attributed to low rock/fluid ratio (Nesbitt et al., 1990 and relatively more pH value (Cheng et al., 2013, however, increasing the Eu anomaly may be due to high rock/fluid ratio and less pH value. Ce anomalies are 0.0241, 0.0113 and 0.0131 in pink, white and green calcites respectively. The most negative Ce anomaly values show that calcite have precipitated under reduction conditions (Nesbitt et al., 1990. Discussion Recently, multiple attributes decision-making techniques help scientist to solve decision-making problems related to various controlling factors (Zhijun et al., 2013. One of these techniques is a Technique for Order Preference by Similarity to Ideal Solution (TOPSIS which is a quantitative weighted method (Momenei 2006. The identified criteria are CaO abundant in solution (C1, Eu anomaly (C2, Ce anomaly (C3, Sr abundant (C4 and volume (C5. The Index-Rock matrix also includes A1, A2 and A3 alternatives; as pink, green and white calcite respectively. The weighted normalized decision matrix can be calculated by multiplying the normalized evaluation matrix with its associated weight to obtain the result. The result show that Eu anomaly, volume, Sr abundant and Ce anomaly in order have higher role to investigate the geochemical study of area. Calculation of the relative closeness to the ideal solution (Cl * for pink, green and white calcites are 0.837, 0.445 and 0.157 respectively. It can be deduced that the most preferable calcite to be sampled for investigating geochemically are pink and green calcites. References Cheng, D.L., Jiang-haob, L., Shou-pengc, Z., Lianga, L., Zhao-bina, Y., Guo-lina, G. and Tinga, L., 2013. Geochemical characteristics of calcite and dolomite in sandstone of Dongying Sinking, Shandong Province, China. Procedia Earth and Planetary Science, 7(4: 504 – 507. Eftekharnezhad, J., 1973

  8. Similarity or difference?

    DEFF Research Database (Denmark)

    Villadsen, Anders Ryom

    2013-01-01

    While the organizational structures and strategies of public organizations have attracted substantial research attention among public management scholars, little research has explored how these organizational core dimensions are interconnected and influenced by pressures for similarity. In this p......While the organizational structures and strategies of public organizations have attracted substantial research attention among public management scholars, little research has explored how these organizational core dimensions are interconnected and influenced by pressures for similarity....... In this paper I address this topic by exploring the relation between expenditure strategy isomorphism and structure isomorphism in Danish municipalities. Different literatures suggest that organizations exist in concurrent pressures for being similar to and different from other organizations in their field...... of action. It is theorized that to meet this challenge organizations may substitute increased similarity on one core dimension for increased idiosyncrasy on another, but only after a certain level of isomorphism is reached. Results of quantitative analyses support this theory and show that an inverse U...

  9. Visualizing multiple word similarity measures.

    Science.gov (United States)

    Kievit-Kylar, Brent; Jones, Michael N

    2012-09-01

    Although many recent advances have taken place in corpus-based tools, the techniques used to guide exploration and evaluation of these systems have advanced little. Typically, the plausibility of a semantic space is explored by sampling the nearest neighbors to a target word and evaluating the neighborhood on the basis of the modeler's intuition. Tools for visualization of these large-scale similarity spaces are nearly nonexistent. We present a new open-source tool to plot and visualize semantic spaces, thereby allowing researchers to rapidly explore patterns in visual data that describe the statistical relations between words. Words are visualized as nodes, and word similarities are shown as directed edges of varying strengths. The "Word-2-Word" visualization environment allows for easy manipulation of graph data to test word similarity measures on their own or in comparisons between multiple similarity metrics. The system contains a large library of statistical relationship models, along with an interface to teach them from various language sources. The modularity of the visualization environment allows for quick insertion of new similarity measures so as to compare new corpus-based metrics against the current state of the art. The software is available at www.indiana.edu/~semantic/word2word/.

  10. Incremental Similarity and Turbulence

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole E.; Hedevang, Emil; Schmiegel, Jürgen

    This paper discusses the mathematical representation of an empirically observed phenomenon, referred to as Incremental Similarity. We discuss this feature from the viewpoint of stochastic processes and present a variety of non-trivial examples, including those that are of relevance for turbulence...

  11. Towards personalized medicine: leveraging patient similarity and drug similarity analytics.

    Science.gov (United States)

    Zhang, Ping; Wang, Fei; Hu, Jianying; Sorrentino, Robert

    2014-01-01

    The rapid adoption of electronic health records (EHR) provides a comprehensive source for exploratory and predictive analytic to support clinical decision-making. In this paper, we investigate how to utilize EHR to tailor treatments to individual patients based on their likelihood to respond to a therapy. We construct a heterogeneous graph which includes two domains (patients and drugs) and encodes three relationships (patient similarity, drug similarity, and patient-drug prior associations). We describe a novel approach for performing a label propagation procedure to spread the label information representing the effectiveness of different drugs for different patients over this heterogeneous graph. The proposed method has been applied on a real-world EHR dataset to help identify personalized treatments for hypercholesterolemia. The experimental results demonstrate the effectiveness of the approach and suggest that the combination of appropriate patient similarity and drug similarity analytics could lead to actionable insights for personalized medicine. Particularly, by leveraging drug similarity in combination with patient similarity, our method could perform well even on new or rarely used drugs for which there are few records of known past performance.

  12. Glove boxes and similar containments

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    According to the present invention a glove box or similar containment is provided with an exhaust system including a vortex amplifier venting into the system, the vortex amplifier also having its main inlet in fluid flow connection with the containment and a control inlet in fluid flow connection with the atmosphere outside the containment. (U.S.)

  13. Similarity and denoising.

    Science.gov (United States)

    Vitányi, Paul M B

    2013-02-13

    We can discover the effective similarity among pairs of finite objects and denoise a finite object using the Kolmogorov complexity of these objects. The drawback is that the Kolmogorov complexity is not computable. If we approximate it, using a good real-world compressor, then it turns out that on natural data the processes give adequate results in practice. The methodology is parameter-free, alignment-free and works on individual data. We illustrate both methods with examples.

  14. More Similar Than Different

    DEFF Research Database (Denmark)

    Pedersen, Mogens Jin

    2018-01-01

    What role do employee features play into the success of different personnel management practices for serving high performance? Using data from a randomized survey experiment among 5,982 individuals of all ages, this article examines how gender conditions the compliance effects of different...... incentive treatments—each relating to the basic content of distinct types of personnel management practices. The findings show that males and females are more similar than different in terms of the incentive treatments’ effects: Significant average effects are found for three out of five incentive...

  15. De fantasmas y similares

    Directory of Open Access Journals (Sweden)

    Ramón Baltar Veloso

    1977-06-01

    Full Text Available A tentative classification of ghost-words by their origin provides the background for the discussion of the possibility that the fish name solas, a hapax legomenon to be found in Pliny’s catalogue of fishes (Nat. 32.151 —according to the very dubious reading of the Bamberg MS— came into existence through a corruption of sepiola.

  16. Medicare Provider Data - Hospice Providers

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Hospice Utilization and Payment Public Use File provides information on services provided to Medicare beneficiaries by hospice providers. The Hospice PUF...

  17. Bridging Database Applications and Declarative Similarity Matching

    OpenAIRE

    Andrade Ribeiro, Leonardo; Schneider, Natália Cristina; de Souza Inácio, Andrei; Wagner, Harley Michel; von Wangenheim, Aldo

    2017-01-01

    Effective manipulation of string data is of fundamental importance to modern database applications. Very often, textual inconsistencies render equality comparisons meaningless and strings have to be matched in terms of their similarity. Previous work has proposed techniques to express similarity operations using declarative SQL statements. However, the non-trivial issue of embedding similarity support into object-oriented applications has received little attention. Particularly, declarative s...

  18. COMPUTATION OF IMAGE SIMILARITY WITH TIME SERIES

    Directory of Open Access Journals (Sweden)

    V. Balamurugan

    2011-11-01

    Full Text Available Searching for similar sequence in large database is an important task in temporal data mining. Similarity search is concerned with efficiently locating subsequences or whole sequences in large archives of sequences. It is useful in typical data mining applications and it can be easily extended to image retrieval. In this work, time series similarity analysis that involves dimensionality reduction and clustering is adapted on digital images to find similarity between them. The dimensionality reduced time series is represented as clusters by the use of K-Means clustering and the similarity distance between two images is found by finding the distance between the signatures of their clusters. To quantify the extent of similarity between two sequences, Earth Mover’s Distance (EMD is used. From the experiments on different sets of images, it is found that this technique is well suited for measuring the subjective similarity between two images.

  19. A technique for determining the optimum mix of logistics service providers of a make-to-order supply chain by formulating and solving a constrained nonlinear cost optimization problem

    Directory of Open Access Journals (Sweden)

    Mrityunjoy Roy

    2013-04-01

    Full Text Available In this paper, a technique has been developed to determine the optimum mix of logistic service providers of a make-to-order (MTO supply chain. A serial MTO supply chain with different stages/ processes has been considered. For each stage different logistic service providers with different mean processing lead times, but same lead time variances are available. A realistic assumption that for each stage, the logistic service provider who charges more for his service consumes less processing lead time and vice-versa has been made in our study. Thus for each stage, for each service provider, a combination of cost and mean processing lead time is available. Using these combinations, for each stage, a polynomial curve, expressing cost of that stage as a function of mean processing lead time is fit. Cumulating all such expressions of cost for the different stages along with incorporation of suitable constraints arising out of timely delivery, results in the formulation of a constrained nonlinear cost optimization problem. On solving the problem using mathematica, optimum processing lead time for each stage is obtained. Using these optimum processing lead times and by employing a simple technique the optimum logistic service provider mix of the supply chain along with the corresponding total cost of processing is determined. Finally to examine the effect of changes in different parameters on the optimum total processing cost of the supply chain, sensitivity analysis has been carried out graphically.

  20. Phishing Detection: Analysis of Visual Similarity Based Approaches

    Directory of Open Access Journals (Sweden)

    Ankit Kumar Jain

    2017-01-01

    Full Text Available Phishing is one of the major problems faced by cyber-world and leads to financial losses for both industries and individuals. Detection of phishing attack with high accuracy has always been a challenging issue. At present, visual similarities based techniques are very useful for detecting phishing websites efficiently. Phishing website looks very similar in appearance to its corresponding legitimate website to deceive users into believing that they are browsing the correct website. Visual similarity based phishing detection techniques utilise the feature set like text content, text format, HTML tags, Cascading Style Sheet (CSS, image, and so forth, to make the decision. These approaches compare the suspicious website with the corresponding legitimate website by using various features and if the similarity is greater than the predefined threshold value then it is declared phishing. This paper presents a comprehensive analysis of phishing attacks, their exploitation, some of the recent visual similarity based approaches for phishing detection, and its comparative study. Our survey provides a better understanding of the problem, current solution space, and scope of future research to deal with phishing attacks efficiently using visual similarity based approaches.

  1. Outsourced Similarity Search on Metric Data Assets

    DEFF Research Database (Denmark)

    Yiu, Man Lung; Assent, Ira; Jensen, Christian S.

    2012-01-01

    This paper considers a cloud computing setting in which similarity querying of metric data is outsourced to a service provider. The data is to be revealed only to trusted users, not to the service provider or anyone else. Users query the server for the most similar data objects to a query example...

  2. On different forms of self similarity

    International Nuclear Information System (INIS)

    Aswathy, R.K.; Mathew, Sunil

    2016-01-01

    Fractal geometry is mainly based on the idea of self-similar forms. To be self-similar, a shape must able to be divided into parts that are smaller copies, which are more or less similar to the whole. There are different forms of self similarity in nature and mathematics. In this paper, some of the topological properties of super self similar sets are discussed. It is proved that in a complete metric space with two or more elements, the set of all non super self similar sets are dense in the set of all non-empty compact sub sets. It is also proved that the product of self similar sets are super self similar in product metric spaces and that the super self similarity is preserved under isometry. A characterization of super self similar sets using contracting sub self similarity is also presented. Some relevant counterexamples are provided. The concepts of exact super and sub self similarity are introduced and a necessary and sufficient condition for a set to be exact super self similar in terms of condensation iterated function systems (Condensation IFS’s) is obtained. A method to generate exact sub self similar sets using condensation IFS’s and the denseness of exact super self similar sets are also discussed.

  3. An efficient similarity measure technique for medical image registration

    Indian Academy of Sciences (India)

    Author Affiliations. Vilas H Gaidhane1 Yogesh V Hote2 Vijander Singh1. Department of Instrumentation and Control Engineering, Netaji Subhas Institute of Technology, University of Delhi, New Delhi, 110 078 India; Department of Electrical Engineering, Indian Institute of Technology, Roorkee, 247 667 India ...

  4. Separation of similar yeast strains by IEF techniques

    Czech Academy of Sciences Publication Activity Database

    Horká, Marie; Růžička, F.; Holá, V.; Šlais, Karel

    2009-01-01

    Roč. 30, č. 12 (2009), s. 2134-2141 ISSN 0173-0835 R&D Projects: GA AV ČR IAAX00310701 Institutional research plan: CEZ:AV0Z40310501 Keywords : biofilm * Candida * lysis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.077, year: 2009

  5. An efficient similarity measure technique for medical image registration

    Indian Academy of Sciences (India)

    are obtained from the reference image by cropping the defective area using Adobe Photoshop. 7.0.1 software. In figure 4, row 1 shows the registration results for the image having the subacute stroke disease. The template image shows the particular affected region. In this experiment, the illu- mination (local distortion) effect ...

  6. Large-Scale Similarity Joins With Guarantees

    DEFF Research Database (Denmark)

    Pagh, Rasmus

    2015-01-01

    The ability to handle noisy or imprecise data is becoming increasingly important in computing. In the database community the notion of similarity join has been studied extensively, yet existing solutions have offered weak performance guarantees. Either they are based on deterministic filtering...... techniques that often, but not always, succeed in reducing computational costs, or they are based on randomized techniques that have improved guarantees on computational cost but come with a probability of not returning the correct result. The aim of this paper is to give an overview of randomized techniques...

  7. Intensity techniques

    DEFF Research Database (Denmark)

    Jacobsen, Finn

    2008-01-01

    The Handbook of Signal Processing in Acoustics will compile the techniques and applications of signal processing as they are used in the many varied areas of Acoustics. The Handbook will emphasize the interdisciplinary nature of signal processing in acoustics. Each Section of the Handbook...... from different areas, will find the self-contained chapters accessible and will be interested in the similarities and differences between the approaches and techniques used in different areas of acoustics....

  8. Reading network in dyslexia: Similar, yet different.

    Science.gov (United States)

    Waldie, Karen E; Wilson, Anna J; Roberts, Reece P; Moreau, David

    2017-11-01

    Dyslexia is a developmental disorder characterized by reading and phonological difficulties, yet important questions remain regarding its underlying neural correlates. In this study, we used partial least squares (PLS), a multivariate analytic technique, to investigate the neural networks used by dyslexics while performing a word-rhyming task. Although the overall reading network was largely similar in dyslexics and typical readers, it did not correlate with behavior in the same way in the two groups. In particular, there was a positive association between reading performance and both right superior temporal gyrus and bilateral insula activation in dyslexic readers but a negative correlation in typical readers. Together with differences in lateralization unique to dyslexics, this suggests that the combination of poor reading performance with high insula activity and atypical laterality is a consistent marker of dyslexia. These findings emphasize the importance of understanding right-hemisphere activation in dyslexia and provide promising directions for the remediation of reading disorders. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. The effect of providing feedback on inhaler technique and adherence from an electronic audio recording device, INCA®, in a community pharmacy setting: study protocol for a randomised controlled trial.

    Science.gov (United States)

    O'Dwyer, Susan Mary; MacHale, Elaine; Sulaiman, Imran; Holmes, Martin; Hughes, Cian; D'Arcy, Shona; Rapcan, Viliam; Taylor, Terence; Boland, Fiona; Bosnic-Anticevich, Sinthia; Reilly, Richard B; Ryder, Sheila A; Costello, Richard W

    2016-05-04

    Poor adherence to inhaled medication may lead to inadequate symptom control in patients with respiratory disease. In practice it can be difficult to identify poor adherence. We designed an acoustic recording device, the INCA® (INhaler Compliance Assessment) device, which, when attached to an inhaler, identifies and records the time and technique of inhaler use, thereby providing objective longitudinal data on an individual's adherence to inhaled medication. This study will test the hypothesis that providing objective, personalised, visual feedback on adherence to patients in combination with a tailored educational intervention in a community pharmacy setting, improves adherence more effectively than education alone. The study is a prospective, cluster randomised, parallel-group, multi-site study conducted over 6 months. The study is designed to compare current best practice in care (i.e. routine inhaler technique training) with the use of the INCA® device for respiratory patients in a community pharmacy setting. Pharmacies are the unit of randomisation and on enrolment to the study they will be allocated by the lead researcher to one of the three study groups (intervention, comparator or control groups) using a computer-generated list of random numbers. Given the nature of the intervention neither pharmacists nor participants can be blinded. The intervention group will receive feedback from the acoustic recording device on inhaler technique and adherence three times over a 6-month period along with inhaler technique training at each of these times. The comparator group will also receive training in inhaler use three times over the 6-month study period but no feedback on their habitual performance. The control group will receive usual care (i.e. the safe supply of medicines and advice on their use). The primary outcome is the rate of participant adherence to their inhaled medication, defined as the proportion of correctly taken doses of medication at the correct

  10. Testing Self-Similarity Through Lamperti Transformations

    KAUST Repository

    Lee, Myoungji

    2016-07-14

    Self-similar processes have been widely used in modeling real-world phenomena occurring in environmetrics, network traffic, image processing, and stock pricing, to name but a few. The estimation of the degree of self-similarity has been studied extensively, while statistical tests for self-similarity are scarce and limited to processes indexed in one dimension. This paper proposes a statistical hypothesis test procedure for self-similarity of a stochastic process indexed in one dimension and multi-self-similarity for a random field indexed in higher dimensions. If self-similarity is not rejected, our test provides a set of estimated self-similarity indexes. The key is to test stationarity of the inverse Lamperti transformations of the process. The inverse Lamperti transformation of a self-similar process is a strongly stationary process, revealing a theoretical connection between the two processes. To demonstrate the capability of our test, we test self-similarity of fractional Brownian motions and sheets, their time deformations and mixtures with Gaussian white noise, and the generalized Cauchy family. We also apply the self-similarity test to real data: annual minimum water levels of the Nile River, network traffic records, and surface heights of food wrappings. © 2016, International Biometric Society.

  11. Renewing the Respect for Similarity

    Directory of Open Access Journals (Sweden)

    Shimon eEdelman

    2012-07-01

    Full Text Available In psychology, the concept of similarity has traditionally evoked a mixture of respect, stemmingfrom its ubiquity and intuitive appeal, and concern, due to its dependence on the framing of the problemat hand and on its context. We argue for a renewed focus on similarity as an explanatory concept, bysurveying established results and new developments in the theory and methods of similarity-preservingassociative lookup and dimensionality reduction — critical components of many cognitive functions, aswell as of intelligent data management in computer vision. We focus in particular on the growing familyof algorithms that support associative memory by performing hashing that respects local similarity, andon the uses of similarity in representing structured objects and scenes. Insofar as these similarity-basedideas and methods are useful in cognitive modeling and in AI applications, they should be included inthe core conceptual toolkit of computational neuroscience.

  12. Semantic Similarity in Biomedical Ontologies

    OpenAIRE

    Pesquita, Catia; Faria, Daniel; Falc?o, Andr? O.; Lord, Phillip; Couto, Francisco M.

    2009-01-01

    In recent years, ontologies have become a mainstream topic in biomedical research. When biological entities are described using a common schema, such as an ontology, they can be compared by means of their annotations. This type of comparison is called semantic similarity, since it assesses the degree of relatedness between two entities by the similarity in meaning of their annotations. The application of semantic similarity to biomedical ontologies is recent; nevertheless, several studies hav...

  13. Similarity Learning of Manifold Data.

    Science.gov (United States)

    Chen, Si-Bao; Ding, Chris H Q; Luo, Bin

    2015-09-01

    Without constructing adjacency graph for neighborhood, we propose a method to learn similarity among sample points of manifold in Laplacian embedding (LE) based on adding constraints of linear reconstruction and least absolute shrinkage and selection operator type minimization. Two algorithms and corresponding analyses are presented to learn similarity for mix-signed and nonnegative data respectively. The similarity learning method is further extended to kernel spaces. The experiments on both synthetic and real world benchmark data sets demonstrate that the proposed LE with new similarity has better visualization and achieves higher accuracy in classification.

  14. Whole Genome Amplification of Day 3 or Day 5 Human Embryos Biopsies Provides a Suitable DNA Template for PCR-Based Techniques for Genotyping, a Complement of Preimplantation Genetic Testing

    Directory of Open Access Journals (Sweden)

    Elizabeth Schaeffer

    2017-01-01

    Full Text Available Our objective was to determine if whole genome amplification (WGA provides suitable DNA for qPCR-based genotyping for human embryos. Single blastomeres (Day 3 or trophoblastic cells (Day 5 were isolated from 342 embryos for WGA. Comparative Genomic Hybridization determined embryo sex as well as Trisomy 18 or Trisomy 21. To determine the embryo’s sex, qPCR melting curve analysis for SRY and DYS14 was used. Logistic regression indicated a 4.4%, 57.1%, or 98.8% probability of a male embryo when neither gene, SRY only, or both genes were detected, respectively (accuracy = 94.1%, kappa = 0.882, and p<0.001. Fluorescent Capillary Electrophoresis for the amelogenin genes (AMEL was also used to determine sex. AMELY peak’s height was higher and this peak’s presence was highly predictive of male embryos (AUC = 0.93, accuracy = 81.7%, kappa = 0.974, and p<0.001. Trisomy 18 and Trisomy 21 were determined using the threshold cycle difference for RPL17 and TTC3, respectively, which were significantly lower in the corresponding embryos. The Ct difference for TTC3 specifically determined Trisomy 21 (AUC = 0.89 and RPL17 for Trisomy 18 (AUC = 0.94. Here, WGA provides adequate DNA for PCR-based techniques for preimplantation genotyping.

  15. Efficient Similarity Retrieval in Music Databases

    DEFF Research Database (Denmark)

    Ruxanda, Maria Magdalena; Jensen, Christian Søndergaard

    2006-01-01

    Audio music is increasingly becoming available in digital form, and the digital music collections of individuals continue to grow. Addressing the need for effective means of retrieving music from such collections, this paper proposes new techniques for content-based similarity search. Each music......, the Vector Approximation file is adapted to the indexing of time sequences and to use a lower bound on the DTW distance. Using these techniques, the paper exploits the lack of a ground truth for queries to efficiently compute query results that differ only slightly from results that may be more accurate...

  16. Multimodal Similarity Gaussian Process Latent Variable Model.

    Science.gov (United States)

    Song, Guoli; Wang, Shuhui; Huang, Qingming; Tian, Qi

    2017-09-01

    Data from real applications involve multiple modalities representing content with the same semantics from complementary aspects. However, relations among heterogeneous modalities are simply treated as observation-to-fit by existing work, and the parameterized modality specific mapping functions lack flexibility in directly adapting to the content divergence and semantic complicacy in multimodal data. In this paper, we build our work based on the Gaussian process latent variable model (GPLVM) to learn the non-parametric mapping functions and transform heterogeneous modalities into a shared latent space. We propose multimodal Similarity Gaussian Process latent variable model (m-SimGP), which learns the mapping functions between the intra-modal similarities and latent representation. We further propose multimodal distance-preserved similarity GPLVM (m-DSimGP) to preserve the intra-modal global similarity structure, and multimodal regularized similarity GPLVM (m-RSimGP) by encouraging similar/dissimilar points to be similar/dissimilar in the latent space. We propose m-DRSimGP, which combines the distance preservation in m-DSimGP and semantic preservation in m-RSimGP to learn the latent representation. The overall objective functions of the four models are solved by simple and scalable gradient decent techniques. They can be applied to various tasks to discover the nonlinear correlations and to obtain the comparable low-dimensional representation for heterogeneous modalities. On five widely used real-world data sets, our approaches outperform existing models on cross-modal content retrieval and multimodal classification.

  17. Similarity joins in relational database systems

    CERN Document Server

    Augsten, Nikolaus

    2013-01-01

    State-of-the-art database systems manage and process a variety of complex objects, including strings and trees. For such objects equality comparisons are often not meaningful and must be replaced by similarity comparisons. This book describes the concepts and techniques to incorporate similarity into database systems. We start out by discussing the properties of strings and trees, and identify the edit distance as the de facto standard for comparing complex objects. Since the edit distance is computationally expensive, token-based distances have been introduced to speed up edit distance comput

  18. Dynamic similarity in erosional processes

    Science.gov (United States)

    Scheidegger, A.E.

    1963-01-01

    A study is made of the dynamic similarity conditions obtaining in a variety of erosional processes. The pertinent equations for each type of process are written in dimensionless form; the similarity conditions can then easily be deduced. The processes treated are: raindrop action, slope evolution and river erosion. ?? 1963 Istituto Geofisico Italiano.

  19. Semantic similarity in biomedical ontologies.

    Directory of Open Access Journals (Sweden)

    Catia Pesquita

    2009-07-01

    Full Text Available In recent years, ontologies have become a mainstream topic in biomedical research. When biological entities are described using a common schema, such as an ontology, they can be compared by means of their annotations. This type of comparison is called semantic similarity, since it assesses the degree of relatedness between two entities by the similarity in meaning of their annotations. The application of semantic similarity to biomedical ontologies is recent; nevertheless, several studies have been published in the last few years describing and evaluating diverse approaches. Semantic similarity has become a valuable tool for validating the results drawn from biomedical studies such as gene clustering, gene expression data analysis, prediction and validation of molecular interactions, and disease gene prioritization. We review semantic similarity measures applied to biomedical ontologies and propose their classification according to the strategies they employ: node-based versus edge-based and pairwise versus groupwise. We also present comparative assessment studies and discuss the implications of their results. We survey the existing implementations of semantic similarity measures, and we describe examples of applications to biomedical research. This will clarify how biomedical researchers can benefit from semantic similarity measures and help them choose the approach most suitable for their studies.Biomedical ontologies are evolving toward increased coverage, formality, and integration, and their use for annotation is increasingly becoming a focus of both effort by biomedical experts and application of automated annotation procedures to create corpora of higher quality and completeness than are currently available. Given that semantic similarity measures are directly dependent on these evolutions, we can expect to see them gaining more relevance and even becoming as essential as sequence similarity is today in biomedical research.

  20. Semantic similarity in biomedical ontologies.

    Science.gov (United States)

    Pesquita, Catia; Faria, Daniel; Falcão, André O; Lord, Phillip; Couto, Francisco M

    2009-07-01

    In recent years, ontologies have become a mainstream topic in biomedical research. When biological entities are described using a common schema, such as an ontology, they can be compared by means of their annotations. This type of comparison is called semantic similarity, since it assesses the degree of relatedness between two entities by the similarity in meaning of their annotations. The application of semantic similarity to biomedical ontologies is recent; nevertheless, several studies have been published in the last few years describing and evaluating diverse approaches. Semantic similarity has become a valuable tool for validating the results drawn from biomedical studies such as gene clustering, gene expression data analysis, prediction and validation of molecular interactions, and disease gene prioritization. We review semantic similarity measures applied to biomedical ontologies and propose their classification according to the strategies they employ: node-based versus edge-based and pairwise versus groupwise. We also present comparative assessment studies and discuss the implications of their results. We survey the existing implementations of semantic similarity measures, and we describe examples of applications to biomedical research. This will clarify how biomedical researchers can benefit from semantic similarity measures and help them choose the approach most suitable for their studies.Biomedical ontologies are evolving toward increased coverage, formality, and integration, and their use for annotation is increasingly becoming a focus of both effort by biomedical experts and application of automated annotation procedures to create corpora of higher quality and completeness than are currently available. Given that semantic similarity measures are directly dependent on these evolutions, we can expect to see them gaining more relevance and even becoming as essential as sequence similarity is today in biomedical research.

  1. Based on Similarity Metric Learning for Semi-Supervised Clustering

    Directory of Open Access Journals (Sweden)

    Wei QIU

    2014-08-01

    Full Text Available Semi-supervised clustering employs a small amount of labeled data to aid unsupervised learning. The focus of this paper is on Metric Learning, with particular interest in incorporating side information to make it semi-supervised. This study is primarily motivated by an application: face-image clustering. In the paper introduces metric learning and semi-supervised clustering, Similarity metric learning method that adapt the underlying similarity metric used by the clustering algorithm. This paper provides new methods for the two approaches as well as presents a new semi-supervised clustering algorithm that integrates both of these techniques in a uniform, principled framework. Experimental results demonstrate that the unified approach produces better clusters than both individual approaches as well as previously proposed semi-supervised clustering algorithms. This paper followed by the discussion of experiments on face-image clustering, as well as future work.

  2. Enhancing quantum annealing performance for the molecular similarity problem

    Science.gov (United States)

    Hernandez, Maritza; Aramon, Maliheh

    2017-05-01

    Quantum annealing is a promising technique which leverages quantum mechanics to solve hard optimization problems. Considerable progress has been made in the development of a physical quantum annealer, motivating the study of methods to enhance the efficiency of such a solver. In this work, we present a quantum annealing approach to measure similarity among molecular structures. Implementing real-world problems on a quantum annealer is challenging due to hardware limitations such as sparse connectivity, intrinsic control error, and limited precision. In order to overcome the limited connectivity, a problem must be reformulated using minor-embedding techniques. Using a real data set, we investigate the performance of a quantum annealer in solving the molecular similarity problem. We provide experimental evidence that common practices for embedding can be replaced by new alternatives which mitigate some of the hardware limitations and enhance its performance. Common practices for embedding include minimizing either the number of qubits or the chain length and determining the strength of ferromagnetic couplers empirically. We show that current criteria for selecting an embedding do not improve the hardware's performance for the molecular similarity problem. Furthermore, we use a theoretical approach to determine the strength of ferromagnetic couplers. Such an approach removes the computational burden of the current empirical approaches and also results in hardware solutions that can benefit from simple local classical improvement. Although our results are limited to the problems considered here, they can be generalized to guide future benchmarking studies.

  3. Method of similarity for cavitation

    Energy Technology Data Exchange (ETDEWEB)

    Espanet, L.; Tekatlian, A.; Barbier, D. [CEA/Cadarache, Dept. d' Etudes des Combustibles (DEC), 13 - Saint-Paul-lez-Durance (France); Gouin, H. [Aix-Marseille-3 Univ., 13 - Marseille (France). Laboratoire de Modelisation en Mecanique et Thermodynamique

    1998-07-01

    The knowledge of possible cavitation in subassembly nozzles of the fast reactor core implies the realization of a fluid dynamic model test. We propose a method of similarity based on the non-dimensionalization of the equation of motion for viscous capillarity fluid issued from the Cahn and Hilliard model. Taking into account the dissolved gas effect, a condition of compatibility is determined. This condition must be respected by the fluid in experiment, along with the scaling between the two similar flows. (author)

  4. Method of similarity for cavitation

    International Nuclear Information System (INIS)

    Espanet, L.; Tekatlian, A.; Barbier, D.; Gouin, H.

    1998-01-01

    The knowledge of possible cavitation in subassembly nozzles of the fast reactor core implies the realization of a fluid dynamic model test. We propose a method of similarity based on the non-dimensionalization of the equation of motion for viscous capillarity fluid issued from the Cahn and Hilliard model. Taking into account the dissolved gas effect, a condition of compatibility is determined. This condition must be respected by the fluid in experiment, along with the scaling between the two similar flows. (author)

  5. Spectral similarity approach for mapping turbidity of an inland waterbody

    Science.gov (United States)

    Garg, Vaibhav; Senthil Kumar, A.; Aggarwal, S. P.; Kumar, Vinay; Dhote, Pankaj R.; Thakur, Praveen K.; Nikam, Bhaskar R.; Sambare, Rohit S.; Siddiqui, Asfa; Muduli, Pradipta R.; Rastogi, Gurdeep

    2017-07-01

    Turbidity is an important quality parameter of water from its optical property point of view. It varies spatio-temporally over large waterbodies and its well distributed measurement on field is tedious and time consuming. Generally, normalized difference turbidity index (NDTI), or band ratio, or regression analysis between turbidity concentration and band reflectance, approaches have been adapted to retrieve turbidity using multispectral remote sensing data. These techniques usually provide qualitative rather than quantitative estimates of turbidity. However, in the present study, spectral similarity analysis, between the spectral characteristics of spaceborne hyperspectral remote sensing data and spectral library generated on field, was carried out to quantify turbidity in the part of Chilika Lake, Odisha, India. Spatial spectral contextual image analysis, spectral angle mapper (SAM) technique was evaluated for the same. The SAM spectral matching technique has been widely used in geological application (mineral mapping), however, the application of this kind of techniques is limited in water quality studies due to non-availability of reference spectral libraries. A spectral library was generated on field for the different concentrations of turbidity using well calibrated instruments like field spectro-radiometer, turbidity meter and hand held global positioning system. The field spectra were classified into 7 classes of turbidity concentration as 100 NTU for analysis. Analysis reveal that at each location in the lake under consideration, the field spectra matched with the image spectra with SAM score of 0.8 and more. The observed turbidity at each location was also very much falling in the estimated turbidity class range. It was observed that the spectral similarity approach provides more quantitative estimate of turbidity as compared to NDTI.

  6. A toolbox for representational similarity analysis.

    Directory of Open Access Journals (Sweden)

    Hamed Nili

    2014-04-01

    Full Text Available Neuronal population codes are increasingly being investigated with multivariate pattern-information analyses. A key challenge is to use measured brain-activity patterns to test computational models of brain information processing. One approach to this problem is representational similarity analysis (RSA, which characterizes a representation in a brain or computational model by the distance matrix of the response patterns elicited by a set of stimuli. The representational distance matrix encapsulates what distinctions between stimuli are emphasized and what distinctions are de-emphasized in the representation. A model is tested by comparing the representational distance matrix it predicts to that of a measured brain region. RSA also enables us to compare representations between stages of processing within a given brain or model, between brain and behavioral data, and between individuals and species. Here, we introduce a Matlab toolbox for RSA. The toolbox supports an analysis approach that is simultaneously data- and hypothesis-driven. It is designed to help integrate a wide range of computational models into the analysis of multichannel brain-activity measurements as provided by modern functional imaging and neuronal recording techniques. Tools for visualization and inference enable the user to relate sets of models to sets of brain regions and to statistically test and compare the models using nonparametric inference methods. The toolbox supports searchlight-based RSA, to continuously map a measured brain volume in search of a neuronal population code with a specific geometry. Finally, we introduce the linear-discriminant t value as a measure of representational discriminability that bridges the gap between linear decoding analyses and RSA. In order to demonstrate the capabilities of the toolbox, we apply it to both simulated and real fMRI data. The key functions are equally applicable to other modalities of brain-activity measurement. The

  7. A Biographic Comparison Tracing the Similarities in the Lives of Jean Piaget and Lev Vygotsky.

    Science.gov (United States)

    Pass, Susan

    This paper focuses on similarities in the lives of Jean Piaget and Lev Vygotsky to enlighten study of their pedagogies and to provide some information for current classroom techniques. Neither man had a great deal to say about his early life, although Piaget published an autobiography. A number of primary sources were used to construct the…

  8. Measuring transferring similarity via local information

    Science.gov (United States)

    Yin, Likang; Deng, Yong

    2018-05-01

    Recommender systems have developed along with the web science, and how to measure the similarity between users is crucial for processing collaborative filtering recommendation. Many efficient models have been proposed (i.g., the Pearson coefficient) to measure the direct correlation. However, the direct correlation measures are greatly affected by the sparsity of dataset. In other words, the direct correlation measures would present an inauthentic similarity if two users have a very few commonly selected objects. Transferring similarity overcomes this drawback by considering their common neighbors (i.e., the intermediates). Yet, the transferring similarity also has its drawback since it can only provide the interval of similarity. To break the limitations, we propose the Belief Transferring Similarity (BTS) model. The contributions of BTS model are: (1) BTS model addresses the issue of the sparsity of dataset by considering the high-order similarity. (2) BTS model transforms uncertain interval to a certain state based on fuzzy systems theory. (3) BTS model is able to combine the transferring similarity of different intermediates using information fusion method. Finally, we compare BTS models with nine different link prediction methods in nine different networks, and we also illustrate the convergence property and efficiency of the BTS model.

  9. Introduction to perturbation techniques

    CERN Document Server

    Nayfeh, Ali H

    2011-01-01

    Similarities, differences, advantages and limitations of perturbation techniques are pointed out concisely. The techniques are described by means of examples that consist mainly of algebraic and ordinary differential equations. Each chapter contains a number of exercises.

  10. Similarities and Differences in Genetics.

    Science.gov (United States)

    Zhang, Yang; Sun, Yan; Liang, Jie; Lu, Lin; Shi, Jie

    2017-01-01

    Similar symptomatology manifestations and high co-morbidity in substance and non-substance addictions suggest that there may be a common pathogenesis between them. Associated with impulse control and emotional processing, the monoamine neurotransmitter system genes are suggested to be related to both substance and non-substance addictions, such as dopamine (DA) system, 5-hydroxytryptamine/serotonin (5-HT) system, the endogenous opioid system and so on. Here we reviewed the similarities and differences in genetics between classic substance addiction and common types of non-substance addiction, e.g. pathological gambling, Internet addiction, binge-eating disorder etc. It is necessary to systematically compare genetic mechanisms of non-substance addiction and substance addiction, which could reveal similarities and differences of substance addiction and non-addictive substances essentially, enhance our understanding of addiction theory and improve clinical practice with research results.

  11. Similarity measures for face recognition

    CERN Document Server

    Vezzetti, Enrico

    2015-01-01

    Face recognition has several applications, including security, such as (authentication and identification of device users and criminal suspects), and in medicine (corrective surgery and diagnosis). Facial recognition programs rely on algorithms that can compare and compute the similarity between two sets of images. This eBook explains some of the similarity measures used in facial recognition systems in a single volume. Readers will learn about various measures including Minkowski distances, Mahalanobis distances, Hansdorff distances, cosine-based distances, among other methods. The book also summarizes errors that may occur in face recognition methods. Computer scientists "facing face" and looking to select and test different methods of computing similarities will benefit from this book. The book is also useful tool for students undertaking computer vision courses.

  12. Scanning ion-selective electrode technique and X-ray microanalysis provide direct evidence of contrasting Na+ transport ability from root to shoot in salt-sensitive cucumber and salt-tolerant pumpkin under NaCl stress.

    Science.gov (United States)

    Lei, Bo; Huang, Yuan; Sun, Jingyu; Xie, Junjun; Niu, Mengliang; Liu, Zhixiong; Fan, Molin; Bie, Zhilong

    2014-12-01

    Grafting onto salt-tolerant pumpkin rootstock can increase cucumber salt tolerance. Previous studies have suggested that this can be attributed to pumpkin roots with higher capacity to limit the transport of Na(+) to the shoot than cucumber roots. However, the mechanism remains unclear. This study investigated the transport of Na(+) in salt-tolerant pumpkin and salt-sensitive cucumber plants under high (200 mM) or moderate (90 mM) NaCl stress. Scanning ion-selective electrode technique showed that pumpkin roots exhibited a higher capacity to extrude Na(+), and a correspondingly increased H(+) influx under 200 or 90 mM NaCl stress. The 200 mM NaCl induced Na(+)/H(+) exchange in the root was inhibited by amiloride (a Na(+)/H(+) antiporter inhibitor) or vanadate [a plasma membrane (PM) H(+) -ATPase inhibitor], indicating that Na(+) exclusion in salt stressed pumpkin and cucumber roots was the result of an active Na(+)/H(+) antiporter across the PM, and the Na(+)/H(+) antiporter system in salt stressed pumpkin roots was sufficient to exclude Na(+) X-ray microanalysis showed higher Na(+) in the cortex, but lower Na(+) in the stele of pumpkin roots than that in cucumber roots under 90 mM NaCl stress, suggesting that the highly vacuolated root cortical cells of pumpkin roots could sequester more Na(+), limit the radial transport of Na(+) to the stele and thus restrict the transport of Na(+) to the shoot. These results provide direct evidence for pumpkin roots with higher capacity to limit the transport of Na(+) to the shoot than cucumber roots. © 2014 Scandinavian Plant Physiology Society.

  13. Comparing methods for single paragraph similarity analysis.

    Science.gov (United States)

    Stone, Benjamin; Dennis, Simon; Kwantes, Peter J

    2011-01-01

    The focus of this paper is two-fold. First, similarities generated from six semantic models were compared to human ratings of paragraph similarity on two datasets-23 World Entertainment News Network paragraphs and 50 ABC newswire paragraphs. Contrary to findings on smaller textual units such as word associations (Griffiths, Tenenbaum, & Steyvers, 2007), our results suggest that when single paragraphs are compared, simple nonreductive models (word overlap and vector space) can provide better similarity estimates than more complex models (LSA, Topic Model, SpNMF, and CSM). Second, various methods of corpus creation were explored to facilitate the semantic models' similarity estimates. Removing numeric and single characters, and also truncating document length improved performance. Automated construction of smaller Wikipedia-based corpora proved to be very effective, even improving upon the performance of corpora that had been chosen for the domain. Model performance was further improved by augmenting corpora with dataset paragraphs. Copyright © 2010 Cognitive Science Society, Inc.

  14. Discovering Music Structure via Similarity Fusion

    DEFF Research Database (Denmark)

    semantics”, in such a way that all observed similarities can be satisfactorily explained using the latent semantics. Therefore, one can think of these semantics as the real structure in music, in the sense that they can explain the observed similarities among songs. The suitability of the PLSA model...... for representing music structure is studied in a simplified scenario consisting of 4412 songs and two similarity measures among them. The results suggest that the PLSA model is a useful framework to combine different sources of information, and provides a reasonable space for song representation.......Automatic methods for music navigation and music recommendation exploit the structure in the music to carry out a meaningful exploration of the “song space”. To get a satisfactory performance from such systems, one should incorporate as much information about songs similarity as possible; however...

  15. Discovering Music Structure via Similarity Fusion

    DEFF Research Database (Denmark)

    Arenas-García, Jerónimo; Parrado-Hernandez, Emilio; Meng, Anders

    Automatic methods for music navigation and music recommendation exploit the structure in the music to carry out a meaningful exploration of the “song space”. To get a satisfactory performance from such systems, one should incorporate as much information about songs similarity as possible; however...... semantics”, in such a way that all observed similarities can be satisfactorily explained using the latent semantics. Therefore, one can think of these semantics as the real structure in music, in the sense that they can explain the observed similarities among songs. The suitability of the PLSA model...... for representing music structure is studied in a simplified scenario consisting of 4412 songs and two similarity measures among them. The results suggest that the PLSA model is a useful framework to combine different sources of information, and provides a reasonable space for song representation....

  16. Revisiting Inter-Genre Similarity

    DEFF Research Database (Denmark)

    Sturm, Bob L.; Gouyon, Fabien

    2013-01-01

    We revisit the idea of ``inter-genre similarity'' (IGS) for machine learning in general, and music genre recognition in particular. We show analytically that the probability of error for IGS is higher than naive Bayes classification with zero-one loss (NB). We show empirically that IGS does...

  17. Assessing semantic similarity of texts - Methods and algorithms

    Science.gov (United States)

    Rozeva, Anna; Zerkova, Silvia

    2017-12-01

    Assessing the semantic similarity of texts is an important part of different text-related applications like educational systems, information retrieval, text summarization, etc. This task is performed by sophisticated analysis, which implements text-mining techniques. Text mining involves several pre-processing steps, which provide for obtaining structured representative model of the documents in a corpus by means of extracting and selecting the features, characterizing their content. Generally the model is vector-based and enables further analysis with knowledge discovery approaches. Algorithms and measures are used for assessing texts at syntactical and semantic level. An important text-mining method and similarity measure is latent semantic analysis (LSA). It provides for reducing the dimensionality of the document vector space and better capturing the text semantics. The mathematical background of LSA for deriving the meaning of the words in a given text by exploring their co-occurrence is examined. The algorithm for obtaining the vector representation of words and their corresponding latent concepts in a reduced multidimensional space as well as similarity calculation are presented.

  18. A Visual lexicon to Handle Semantic Similarity in Design precedents

    DEFF Research Database (Denmark)

    Restrepo-Giraldo, John Dairo

    2007-01-01

    . The shaping and establishing of this image is supported by creating sketches, collages, models and other types of external representations. This process is largely supported by the use of design precedents. In design, precedents provide the frame of reference for the development of new solution principles...... by many researchers that have tried to support the process by providing computer tools. Many of these tools have the drawback of relying on metadata added to the image by the editor of the collection. In all the tools studies for this research, such metadata contained, among other things, descriptions...... recognition techniques to index and retrieve visual information called Content Based Image Retrieval (CBIR). In this approach, the designer gives the computer tool an image and the computer searches for images that are similar to the example given. For this, the computer looks for geometrical features...

  19. Active browsing using similarity pyramids

    Science.gov (United States)

    Chen, Jau-Yuen; Bouman, Charles A.; Dalton, John C.

    1998-12-01

    In this paper, we describe a new approach to managing large image databases, which we call active browsing. Active browsing integrates relevance feedback into the browsing environment, so that users can modify the database's organization to suit the desired task. Our method is based on a similarity pyramid data structure, which hierarchically organizes the database, so that it can be efficiently browsed. At coarse levels, the similarity pyramid allows users to view the database as large clusters of similar images. Alternatively, users can 'zoom into' finer levels to view individual images. We discuss relevance feedback for the browsing process, and argue that it is fundamentally different from relevance feedback for more traditional search-by-query tasks. We propose two fundamental operations for active browsing: pruning and reorganization. Both of these operations depend on a user-defined relevance set, which represents the image or set of images desired by the user. We present statistical methods for accurately pruning the database, and we propose a new 'worm hole' distance metric for reorganizing the database, so that members of the relevance set are grouped together.

  20. Finding Protein and Nucleotide Similarities with FASTA.

    Science.gov (United States)

    Pearson, William R

    2016-03-24

    The FASTA programs provide a comprehensive set of rapid similarity searching tools (fasta36, fastx36, tfastx36, fasty36, tfasty36), similar to those provided by the BLAST package, as well as programs for slower, optimal, local, and global similarity searches (ssearch36, ggsearch36), and for searching with short peptides and oligonucleotides (fasts36, fastm36). The FASTA programs use an empirical strategy for estimating statistical significance that accommodates a range of similarity scoring matrices and gap penalties, improving alignment boundary accuracy and search sensitivity. The FASTA programs can produce "BLAST-like" alignment and tabular output, for ease of integration into existing analysis pipelines, and can search small, representative databases, and then report results for a larger set of sequences, using links from the smaller dataset. The FASTA programs work with a wide variety of database formats, including mySQL and postgreSQL databases. The programs also provide a strategy for integrating domain and active site annotations into alignments and highlighting the mutational state of functionally critical residues. These protocols describe how to use the FASTA programs to characterize protein and DNA sequences, using protein:protein, protein:DNA, and DNA:DNA comparisons. Copyright © 2016 John Wiley & Sons, Inc.

  1. Protein structural similarity search by Ramachandran codes

    Directory of Open Access Journals (Sweden)

    Chang Chih-Hung

    2007-08-01

    Full Text Available Abstract Background Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed, several methods have been designed to reduce three-dimensional protein structures to one-dimensional text strings that are then analyzed by traditional sequence alignment methods; however, the accuracy is usually sacrificed and the speed is still unable to match sequence similarity search tools. Here, we aimed to improve the linear encoding methodology and develop efficient search tools that can rapidly retrieve structural homologs from large protein databases. Results We propose a new linear encoding method, SARST (Structural similarity search Aided by Ramachandran Sequential Transformation. SARST transforms protein structures into text strings through a Ramachandran map organized by nearest-neighbor clustering and uses a regenerative approach to produce substitution matrices. Then, classical sequence similarity search methods can be applied to the structural similarity search. Its accuracy is similar to Combinatorial Extension (CE and works over 243,000 times faster, searching 34,000 proteins in 0.34 sec with a 3.2-GHz CPU. SARST provides statistically meaningful expectation values to assess the retrieved information. It has been implemented into a web service and a stand-alone Java program that is able to run on many different platforms. Conclusion As a database search method, SARST can rapidly distinguish high from low similarities and efficiently retrieve homologous structures. It demonstrates that the easily accessible linear encoding methodology has the potential to serve as a foundation for efficient protein structural similarity search tools. These search tools are supposed applicable to automated and high-throughput functional annotations or predictions for the ever increasing number of published protein structures in this post-genomic era.

  2. An Integrated Multicriteria Decision-Making Approach for Evaluating Nuclear Fuel Cycle Systems for Long-term Sustainability on the Basis of an Equilibrium Model: Technique for Order of Preference by Similarity to Ideal Solution, Preference Ranking Organization Method for Enrichment Evaluation, and Multiattribute Utility Theory Combined with Analytic Hierarchy Process

    Directory of Open Access Journals (Sweden)

    Saerom Yoon

    2017-02-01

    Full Text Available The focus on the issues surrounding spent nuclear fuel and lifetime extension of old nuclear power plants continues to grow nowadays. A transparent decision-making process to identify the best suitable nuclear fuel cycle (NFC is considered to be the key task in the current situation. Through this study, an attempt is made to develop an equilibrium model for the NFC to calculate the material flows based on 1 TWh of electricity production, and to perform integrated multicriteria decision-making method analyses via the analytic hierarchy process technique for order of preference by similarity to ideal solution, preference ranking organization method for enrichment evaluation, and multiattribute utility theory methods. This comparative study is aimed at screening and ranking the three selected NFC options against five aspects: sustainability, environmental friendliness, economics, proliferation resistance, and technical feasibility. The selected fuel cycle options include pressurized water reactor (PWR once-through cycle, PWR mixed oxide cycle, or pyroprocessing sodium-cooled fast reactor cycle. A sensitivity analysis was performed to prove the robustness of the results and explore the influence of criteria on the obtained ranking. As a result of the comparative analysis, the pyroprocessing sodium-cooled fast reactor cycle is determined to be the most competitive option among the NFC scenarios.

  3. An integrated multicriteria decision-making approach for evaluating nuclear fuel cycle systems for long-term sustainability on the basis of an equilibrium model: Technique for order of preference by similarity to ideal solution, preference ranking organization method for enrichment evaluation, and multiattribute utility theory combined with analytic hierarchy process

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sae Rom [Dept of Quantum Energy Chemical Engineering, Korea University of Science and Technology (KUST), Daejeon (Korea, Republic of); Choi, Sung Yeol [Ulsan National Institute of Science and Technology, Ulju (Korea, Republic of); Ko, Wonil [Nonproliferation System Development Division, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2017-02-15

    The focus on the issues surrounding spent nuclear fuel and lifetime extension of old nuclear power plants continues to grow nowadays. A transparent decision-making process to identify the best suitable nuclear fuel cycle (NFC) is considered to be the key task in the current situation. Through this study, an attempt is made to develop an equilibrium model for the NFC to calculate the material flows based on 1 TWh of electricity production, and to perform integrated multicriteria decision-making method analyses via the analytic hierarchy process technique for order of preference by similarity to ideal solution, preference ranking organization method for enrichment evaluation, and multiattribute utility theory methods. This comparative study is aimed at screening and ranking the three selected NFC options against five aspects: sustainability, environmental friendliness, economics, proliferation resistance, and technical feasibility. The selected fuel cycle options include pressurized water reactor (PWR) once-through cycle, PWR mixed oxide cycle, or pyroprocessing sodium-cooled fast reactor cycle. A sensitivity analysis was performed to prove the robustness of the results and explore the influence of criteria on the obtained ranking. As a result of the comparative analysis, the pyroprocessing sodium-cooled fast reactor cycle is determined to be the most competitive option among the NFC scenarios.

  4. Seniority bosons from similarity transformations

    International Nuclear Information System (INIS)

    Geyer, H.B.

    1986-01-01

    The requirement of associating in the boson space seniority with twice the number of non-s bosons defines a similarity transformation which re-expresses the Dyson pair boson images in terms of seniority bosons. In particular the fermion S-pair creation operator is mapped onto an operator which, unlike the pair boson image, does not change the number of non-s bosons. The original results of Otsuka, Arima and Iachello are recovered by this procedure while at the same time they are generalized to include g-bosons or even bosons with J>4 as well as any higher order boson terms. Furthermore the seniority boson images are valid for an arbitrary number of d- or g-bosons - a result which is not readily obtainable within the framework of the usual Marumori- or OAI-method

  5. Semantic similarity between ontologies at different scales

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Qingpeng; Haglin, David J.

    2016-04-01

    In the past decade, existing and new knowledge and datasets has been encoded in different ontologies for semantic web and biomedical research. The size of ontologies is often very large in terms of number of concepts and relationships, which makes the analysis of ontologies and the represented knowledge graph computational and time consuming. As the ontologies of various semantic web and biomedical applications usually show explicit hierarchical structures, it is interesting to explore the trade-offs between ontological scales and preservation/precision of results when we analyze ontologies. This paper presents the first effort of examining the capability of this idea via studying the relationship between scaling biomedical ontologies at different levels and the semantic similarity values. We evaluate the semantic similarity between three Gene Ontology slims (Plant, Yeast, and Candida, among which the latter two belong to the same kingdom—Fungi) using four popular measures commonly applied to biomedical ontologies (Resnik, Lin, Jiang-Conrath, and SimRel). The results of this study demonstrate that with proper selection of scaling levels and similarity measures, we can significantly reduce the size of ontologies without losing substantial detail. In particular, the performance of Jiang-Conrath and Lin are more reliable and stable than that of the other two in this experiment, as proven by (a) consistently showing that Yeast and Candida are more similar (as compared to Plant) at different scales, and (b) small deviations of the similarity values after excluding a majority of nodes from several lower scales. This study provides a deeper understanding of the application of semantic similarity to biomedical ontologies, and shed light on how to choose appropriate semantic similarity measures for biomedical engineering.

  6. Inferring gene ontologies from pairwise similarity data

    Science.gov (United States)

    Kramer, Michael; Dutkowski, Janusz; Yu, Michael; Bafna, Vineet; Ideker, Trey

    2014-01-01

    Motivation: While the manually curated Gene Ontology (GO) is widely used, inferring a GO directly from -omics data is a compelling new problem. Recognizing that ontologies are a directed acyclic graph (DAG) of terms and hierarchical relations, algorithms are needed that: analyze a full matrix of gene–gene pairwise similarities from -omics data;infer true hierarchical structure in these data rather than enforcing hierarchy as a computational artifact; andrespect biological pleiotropy, by which a term in the hierarchy can relate to multiple higher level terms. Methods addressing these requirements are just beginning to emerge—none has been evaluated for GO inference. Methods: We consider two algorithms [Clique Extracted Ontology (CliXO), LocalFitness] that uniquely satisfy these requirements, compared with methods including standard clustering. CliXO is a new approach that finds maximal cliques in a network induced by progressive thresholding of a similarity matrix. We evaluate each method’s ability to reconstruct the GO biological process ontology from a similarity matrix based on (a) semantic similarities for GO itself or (b) three -omics datasets for yeast. Results: For task (a) using semantic similarity, CliXO accurately reconstructs GO (>99% precision, recall) and outperforms other approaches (Ontology) and better than LocalFitness or standard clustering (20–25% precision, recall). Conclusion: This study provides algorithmic foundation for building gene ontologies by capturing hierarchical and pleiotropic structure embedded in biomolecular data. Contact: tideker@ucsd.edu PMID:24932003

  7. Providing Compassion through Flow

    Directory of Open Access Journals (Sweden)

    Lydia Royeen

    2015-07-01

    Full Text Available Meg Kral, MS, OTR/L, CLT, is the cover artist for the Summer 2015 issue of The Open Journal of Occupational Therapy. Her untitled piece of art is an oil painting and is a re-creation of a photograph taken while on vacation. Meg is currently supervisor of outpatient services at Rush University Medical Center. She is lymphedema certified and has a specific interest in breast cancer lymphedema. Art and occupational therapy serve similar purposes for Meg: both provide a sense of flow. She values the outcomes, whether it is a piece of art or improved functional status

  8. Liraglutide provides similar glycaemic control as glimepiride (both in combination with metformin) and reduces body weight and systolic blood pressure in Asian population with type 2 diabetes from China, South Korea and India: a 16-week, randomized, double-blind, active control trial(*).

    Science.gov (United States)

    Yang, W; Chen, L; Ji, Q; Liu, X; Ma, J; Tandon, N; Bhattacharyya, A; Kumar, A; Kim, K-W; Yoon, K-H; Bech, O M; Zychma, M

    2011-01-01

    To assess and compare the efficacy and safety of liraglutide with those of glimepiride, both in combination with metformin for the treatment of type 2 diabetes in Asian population from China, South Korea and India. A 16-week, randomized, double-blind, double-dummy, four-arm, active control trial was carried out. In total, 929 subjects with type 2 diabetes with a mean (±s.d.) age of 53.3 ± 9.5 years, HbA₁(c) of 8.6 ± 1.0% and body weight of 68.1 ± 11.7 kg were randomized (liraglutide 0.6, 1.2 or 1.8 mg once daily or glimepiride 4 mg once daily all in combination with metformin: 1 : 1 : 1 : 1). One subject withdrew immediately after randomization and before exposure. HbA₁(c) was significantly reduced in all groups compared with baseline. Treatment with liraglutide 1.2 and 1.8 mg was non-inferior to glimepiride (mean HbA₁(c) reduction: 1.36% points, 1.45% points and 1.39% points, respectively). No significant difference was shown in the percentage of subjects reaching American Diabetes Association HbA₁(c) target <7% or American Association of Clinical Endocrinologists target ≤6.5% between liraglutide 1.2 and 1.8 mg and glimepiride. Liraglutide was associated with a 1.8-2.4 kg mean weight reduction, compared with a 0.1 kg mean weight gain with glimepiride. Liraglutide led to a significantly greater reduction in systolic blood pressure (SBP) compared with glimepiride. Two subjects in the glimepiride group reported major hypoglycaemia while none in the liraglutide groups. Liraglutide was associated with about 10-fold lower incidence of minor hypoglycaemia than glimepiride. Gastrointestinal disorders were the most common adverse events (AEs) for liraglutide, but were transient and resulted in few withdrawals. In Asian subjects with type 2 diabetes, once-daily liraglutide led to improvement in glycaemic control similar to that with glimepiride but with less frequent major and minor hypoglycaemia. Liraglutide also induced a significant weight loss and reduced

  9. A protocol for a randomised clinical trial of the effect of providing feedback on inhaler technique and adherence from an electronic device in patients with poorly controlled severe asthma.

    Science.gov (United States)

    Sulaiman, Imran; Mac Hale, Elaine; Holmes, Martin; Hughes, Cian; D'Arcy, Shona; Taylor, Terrence; Rapcan, Viliam; Doyle, Frank; Breathnach, Aoife; Seheult, Jansen; Murphy, Desmond; Hunt, Eoin; Lane, Stephen J; Sahadevan, Abhilash; Crispino, Gloria; Diette, Greg; Killane, Isabelle; Reilly, Richard B; Costello, Richard W

    2016-01-04

    In clinical practice, it is difficult to distinguish between patients with refractory asthma from those with poorly controlled asthma, where symptoms persist due to poor adherence, inadequate inhaler technique or comorbid diseases. We designed an audio recording device which, when attached to an inhaler, objectively identifies the time and technique of inhaler use, thereby assessing both aspects of adherence. This study will test the hypothesis that feedback on these two aspects of adherence when passed on to patients improves adherence and helps clinicians distinguish refractory from difficult-to-control asthma. This is a single, blind, prospective, randomised, clinical trial performed at 5 research centres. Patients with partially controlled or uncontrolled severe asthma who have also had at least one severe asthma exacerbation in the prior year are eligible to participate. The effect of two types of nurse-delivered education interventions to promote adherence and inhaler technique will be assessed. The active group will receive feedback on their inhaler technique and adherence from the new device over a 3-month period. The control group will also receive training in inhaler technique and strategies to promote adherence, but no feedback from the device. The primary outcome is the difference in actual adherence, a measure that incorporates time and technique of inhaler use between groups at the end of the third month. Secondary outcomes include the number of patients who remain refractory despite good adherence, and differences in the components of adherence after the intervention. Data will be analysed on an intention-to-treat and a per-protocol basis. The sample size is 220 subjects (110 in each group), and loss to follow-up is estimated at 10% which will allow results to show a 10% difference (0.8 power) in adherence between group means with a type I error probability of 0.05. NCT01529697; Pre-results. Published by the BMJ Publishing Group Limited. For

  10. Visual reconciliation of alternative similarity spaces in climate modeling

    Science.gov (United States)

    J Poco; A Dasgupta; Y Wei; William Hargrove; C.R. Schwalm; D.N. Huntzinger; R Cook; E Bertini; C.T. Silva

    2015-01-01

    Visual data analysis often requires grouping of data objects based on their similarity. In many application domains researchers use algorithms and techniques like clustering and multidimensional scaling to extract groupings from data. While extracting these groups using a single similarity criteria is relatively straightforward, comparing alternative criteria poses...

  11. Relationship between genetic similarity and some productive traits ...

    African Journals Online (AJOL)

    Admin

    Random amplified polymorphic DNA (RAPD) technique was applied to detect genetic similarity between five local chicken strains that have been selected for eggs and meat production in Egypt. Based on six oligonucleotide primers, the genetic similarity between the egg-producing strains (Anshas, Silver. Montazah and ...

  12. Large margin classification with indefinite similarities

    KAUST Repository

    Alabdulmohsin, Ibrahim

    2016-01-07

    Classification with indefinite similarities has attracted attention in the machine learning community. This is partly due to the fact that many similarity functions that arise in practice are not symmetric positive semidefinite, i.e. the Mercer condition is not satisfied, or the Mercer condition is difficult to verify. Examples of such indefinite similarities in machine learning applications are ample including, for instance, the BLAST similarity score between protein sequences, human-judged similarities between concepts and words, and the tangent distance or the shape matching distance in computer vision. Nevertheless, previous works on classification with indefinite similarities are not fully satisfactory. They have either introduced sources of inconsistency in handling past and future examples using kernel approximation, settled for local-minimum solutions using non-convex optimization, or produced non-sparse solutions by learning in Krein spaces. Despite the large volume of research devoted to this subject lately, we demonstrate in this paper how an old idea, namely the 1-norm support vector machine (SVM) proposed more than 15 years ago, has several advantages over more recent work. In particular, the 1-norm SVM method is conceptually simpler, which makes it easier to implement and maintain. It is competitive, if not superior to, all other methods in terms of predictive accuracy. Moreover, it produces solutions that are often sparser than more recent methods by several orders of magnitude. In addition, we provide various theoretical justifications by relating 1-norm SVM to well-established learning algorithms such as neural networks, SVM, and nearest neighbor classifiers. Finally, we conduct a thorough experimental evaluation, which reveals that the evidence in favor of 1-norm SVM is statistically significant.

  13. What Can We Learn from Similar Male Dominated Industries?

    International Nuclear Information System (INIS)

    Thomas, C.

    2015-01-01

    Thomas Thor Associates is an Executive Recruitment company solely dedicated to the Nuclear industry. We have been involved with WiN UK in 2014–2015 to help them develop their own organization, this research was part of our partnership. The main purpose of this paper is to provide a clear picture of the techniques that are used by organizations similar to WiN, and business in other industries that are similar to Nuclear, to attract more women to pursue a career in a particular industry, and to support retention and career progression of women in these industries. This paper has taken a look at all industries that require technical and engineering staff, after which the Mining, Oil & Gas, Petro-chemicals, Rail, Renewable Energy, Technology and Construction industries were found to show most similarities with Nuclear, in terms of the technical staff required and their structure on gender diversity. From here, case studies of industry organizations and professional business have been prepared in order to inform WiN of best practice in these industries and provide a benchmark for future WiN operations. Finally, the report results into giving recommendations on projects WiN could add to their current approach to achieve their objectives. The recommendations are based on the results from the case studies, focusing on attracting, recruiting, retaining and developing female professionals. In summary, the recommendations are to: highlight potential career paths for women in Nuclear, educate women on Nuclear, support the development of women and to help companies to increase their bottom line by getting WiN certified. (author)

  14. PubChem3D: Biologically relevant 3-D similarity

    Directory of Open Access Journals (Sweden)

    Kim Sunghwan

    2011-07-01

    Full Text Available Abstract Background The use of 3-D similarity techniques in the analysis of biological data and virtual screening is pervasive, but what is a biologically meaningful 3-D similarity value? Can one find statistically significant separation between "active/active" and "active/inactive" spaces? These questions are explored using 734,486 biologically tested chemical structures, 1,389 biological assay data sets, and six different 3-D similarity types utilized by PubChem analysis tools. Results The similarity value distributions of 269.7 billion unique conformer pairs from 734,486 biologically tested compounds (all-against-all from PubChem were utilized to help work towards an answer to the question: what is a biologically meaningful 3-D similarity score? The average and standard deviation for the six similarity measures STST-opt, CTST-opt, ComboTST-opt, STCT-opt, CTCT-opt, and ComboTCT-opt were 0.54 ± 0.10, 0.07 ± 0.05, 0.62 ± 0.13, 0.41 ± 0.11, 0.18 ± 0.06, and 0.59 ± 0.14, respectively. Considering that this random distribution of biologically tested compounds was constructed using a single theoretical conformer per compound (the "default" conformer provided by PubChem, further study may be necessary using multiple diverse conformers per compound; however, given the breadth of the compound set, the single conformer per compound results may still apply to the case of multi-conformer per compound 3-D similarity value distributions. As such, this work is a critical step, covering a very wide corpus of chemical structures and biological assays, creating a statistical framework to build upon. The second part of this study explored the question of whether it was possible to realize a statistically meaningful 3-D similarity value separation between reputed biological assay "inactives" and "actives". Using the terminology of noninactive-noninactive (NN pairs and the noninactive-inactive (NI pairs to represent comparison of the "active/active" and

  15. New techniques in television to provide research in three-dimensional real-time or near real-time imagery and reduced cost systems for teleconferencing and educational uses, part 1

    Science.gov (United States)

    Pao, Y. H.; Claspy, P.; Allen, J. E.; Merat, F.

    1979-01-01

    The results are presented of a continuing research and development program the objective of which is to develop a reduced bandwidth television system and a technique for television transmission of holograms. The result of the former is a variable frame rate television system, the operation of which was demonstrated for both black-and-white and color signals. This system employs a novel combination of the inexpensive mass storage capacity of a magnetic disc with the reliability of a digital system for time expansion and compression. Also reported are the results of a theoretical analysis and preliminary feasibility experiment of an innovative system for television transmission of holograms using relatively conventional TV equipment along with a phase modulated reference wave for production of the original interference pattern.

  16. New similarity search based glioma grading

    Energy Technology Data Exchange (ETDEWEB)

    Haegler, Katrin; Brueckmann, Hartmut; Linn, Jennifer [Ludwig-Maximilians-University of Munich, Department of Neuroradiology, Munich (Germany); Wiesmann, Martin; Freiherr, Jessica [RWTH Aachen University, Department of Neuroradiology, Aachen (Germany); Boehm, Christian [Ludwig-Maximilians-University of Munich, Department of Computer Science, Munich (Germany); Schnell, Oliver; Tonn, Joerg-Christian [Ludwig-Maximilians-University of Munich, Department of Neurosurgery, Munich (Germany)

    2012-08-15

    MR-based differentiation between low- and high-grade gliomas is predominately based on contrast-enhanced T1-weighted images (CE-T1w). However, functional MR sequences as perfusion- and diffusion-weighted sequences can provide additional information on tumor grade. Here, we tested the potential of a recently developed similarity search based method that integrates information of CE-T1w and perfusion maps for non-invasive MR-based glioma grading. We prospectively included 37 untreated glioma patients (23 grade I/II, 14 grade III gliomas), in whom 3T MRI with FLAIR, pre- and post-contrast T1-weighted, and perfusion sequences was performed. Cerebral blood volume, cerebral blood flow, and mean transit time maps as well as CE-T1w images were used as input for the similarity search. Data sets were preprocessed and converted to four-dimensional Gaussian Mixture Models that considered correlations between the different MR sequences. For each patient, a so-called tumor feature vector (= probability-based classifier) was defined and used for grading. Biopsy was used as gold standard, and similarity based grading was compared to grading solely based on CE-T1w. Accuracy, sensitivity, and specificity of pure CE-T1w based glioma grading were 64.9%, 78.6%, and 56.5%, respectively. Similarity search based tumor grading allowed differentiation between low-grade (I or II) and high-grade (III) gliomas with an accuracy, sensitivity, and specificity of 83.8%, 78.6%, and 87.0%. Our findings indicate that integration of perfusion parameters and CE-T1w information in a semi-automatic similarity search based analysis improves the potential of MR-based glioma grading compared to CE-T1w data alone. (orig.)

  17. New similarity search based glioma grading.

    Science.gov (United States)

    Haegler, Katrin; Wiesmann, Martin; Böhm, Christian; Freiherr, Jessica; Schnell, Oliver; Brückmann, Hartmut; Tonn, Jörg-Christian; Linn, Jennifer

    2012-08-01

    MR-based differentiation between low- and high-grade gliomas is predominately based on contrast-enhanced T1-weighted images (CE-T1w). However, functional MR sequences as perfusion- and diffusion-weighted sequences can provide additional information on tumor grade. Here, we tested the potential of a recently developed similarity search based method that integrates information of CE-T1w and perfusion maps for non-invasive MR-based glioma grading. We prospectively included 37 untreated glioma patients (23 grade I/II, 14 grade III gliomas), in whom 3T MRI with FLAIR, pre- and post-contrast T1-weighted, and perfusion sequences was performed. Cerebral blood volume, cerebral blood flow, and mean transit time maps as well as CE-T1w images were used as input for the similarity search. Data sets were preprocessed and converted to four-dimensional Gaussian Mixture Models that considered correlations between the different MR sequences. For each patient, a so-called tumor feature vector (= probability-based classifier) was defined and used for grading. Biopsy was used as gold standard, and similarity based grading was compared to grading solely based on CE-T1w. Accuracy, sensitivity, and specificity of pure CE-T1w based glioma grading were 64.9%, 78.6%, and 56.5%, respectively. Similarity search based tumor grading allowed differentiation between low-grade (I or II) and high-grade (III) gliomas with an accuracy, sensitivity, and specificity of 83.8%, 78.6%, and 87.0%. Our findings indicate that integration of perfusion parameters and CE-T1w information in a semi-automatic similarity search based analysis improves the potential of MR-based glioma grading compared to CE-T1w data alone.

  18. Fast approximate hierarchical clustering using similarity heuristics

    Directory of Open Access Journals (Sweden)

    Kull Meelis

    2008-09-01

    Full Text Available Abstract Background Agglomerative hierarchical clustering (AHC is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that all pairwise distances between data objects must be known. With ever-increasing data sizes this quadratic complexity poses problems that cannot be overcome by simply waiting for faster computers. Results We propose an approximate AHC algorithm HappieClust which can output a biologically meaningful clustering of a large dataset more than an order of magnitude faster than full AHC algorithms. The key to the algorithm is to limit the number of calculated pairwise distances to a carefully chosen subset of all possible distances. We choose distances using a similarity heuristic based on a small set of pivot objects. The heuristic efficiently finds pairs of similar objects and these help to mimic the greedy choices of full AHC. Quality of approximate AHC as compared to full AHC is studied with three measures. The first measure evaluates the global quality of the achieved clustering, while the second compares biological relevance using enrichment of biological functions in every subtree of the clusterings. The third measure studies how well the contents of subtrees are conserved between the clusterings. Conclusion The HappieClust algorithm is well suited for large-scale gene expression visualization and analysis both on personal computers as well as public online web applications. The software is available from the URL http://www.quretec.com/HappieClust

  19. Gait Recognition Using Image Self-Similarity

    Directory of Open Access Journals (Sweden)

    Chiraz BenAbdelkader

    2004-04-01

    Full Text Available Gait is one of the few biometrics that can be measured at a distance, and is hence useful for passive surveillance as well as biometric applications. Gait recognition research is still at its infancy, however, and we have yet to solve the fundamental issue of finding gait features which at once have sufficient discrimination power and can be extracted robustly and accurately from low-resolution video. This paper describes a novel gait recognition technique based on the image self-similarity of a walking person. We contend that the similarity plot encodes a projection of gait dynamics. It is also correspondence-free, robust to segmentation noise, and works well with low-resolution video. The method is tested on multiple data sets of varying sizes and degrees of difficulty. Performance is best for fronto-parallel viewpoints, whereby a recognition rate of 98% is achieved for a data set of 6 people, and 70% for a data set of 54 people.

  20. Developing a similarity searching module for patient safety event reporting system using semantic similarity measures.

    Science.gov (United States)

    Kang, Hong; Gong, Yang

    2017-07-05

    The most important knowledge in the field of patient safety is regarding the prevention and reduction of patient safety events (PSE) during treatment and care. The similarities and patterns among the events may otherwise go unnoticed if they are not properly reported and analyzed. There is an urgent need for developing a PSE reporting system that can dynamically measure the similarities of the events and thus promote event analysis and learning effect. In this study, three prevailing algorithms of semantic similarity were implemented to measure the similarities of the 366 PSE annotated by the taxonomy of The Agency for Healthcare Research and Quality (AHRQ). The performance of each algorithm was then evaluated by a group of domain experts based on a 4-point Likert scale. The consistency between the scales of the algorithms and experts was measured and compared with the scales randomly assigned. The similarity algorithms and scores, as a self-learning and self-updating module, were then integrated into the system. The result shows that the similarity scores reflect a high consistency with the experts' review than those randomly assigned. Moreover, incorporating the algorithms into our reporting system enables a mechanism to learn and update based upon PSE similarity. In conclusion, integrating semantic similarity algorithms into a PSE reporting system can help us learn from previous events and provide timely knowledge support to the reporters. With the knowledge base in the PSE domain, the new generation reporting system holds promise in educating healthcare providers and preventing the recurrence and serious consequences of PSE.

  1. Usage Pattern Differences and Similarities of Mobile Electronic Medical Records Among Health Care Providers.

    Science.gov (United States)

    Lee, Yura; Park, Yu Rang; Kim, Junetae; Kim, Jeong Hoon; Kim, Woo Sung; Lee, Jae-Ho

    2017-12-13

    Recently, many hospitals have introduced mobile electronic medical records (mEMRs). Although numerous studies have been published on the usability or usage patterns of mEMRs through user surveys, investigations based on the real data usage are lacking. Asan Medical Center, a tertiary hospital in Seoul, Korea, implemented an mEMR program in 2010. On the basis of the mEMR usage log data collected over a period of 4.5 years, we aimed to identify a usage pattern and trends in accordance with user occupation and to disseminate the factors that make the mEMR more effective and efficient. The mEMR log data were collected from March 2012 to August 2016. Descriptive analyses were completed according to user occupation, access time, services, and wireless network type. Specifically, analyses targeted were as follows: (1) the status of the mEMR usage and distribution of users, (2) trends in the number of users and usage amount, (3) 24-hour usage patterns, and (4) trends in service usage based on user occupations. Linear regressions were performed to model the relationship between the time, access frequency, and the number of users. The differences between the user occupations were examined using Student t tests for categorical variables. Approximately two-thirds of the doctors and nurses used the mEMR. The number of logs studied was 7,144,459. Among 3859 users, 2333 (60.46%) users were nurses and 1102 (28.56%) users were doctors. On average, the mEMR was used 1044 times by 438 users per day. The number of users and amount of access logs have significantly increased since 2012 (Pusage periods were observed during 08:00 to 09:00 and 17:00 to 18:00, which were coincident with the beginning of ward rounds. Conversely, the peak usage periods for the nurses were observed during 05:00 to 06:00, 12:00 to 13:00, and 20:00 to 21:00, which effectively occurred 1 or 2 hours before handover. In more than 80% of all cases, the mEMR was accessed via a nonhospital wireless network. The usage patterns of the mEMR differed between doctors and nurses according to their different workflows. In both occupations, mEMR was highly used when personal computer access was limited and the need for patient information was high, such as during ward rounds or handover periods. ©Yura Lee, Yu Rang Park, Junetae Kim, Jeong Hoon Kim, Woo Sung Kim, Jae-Ho Lee. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 13.12.2017.

  2. Similarity from multi-dimensional scaling: solving the accuracy and diversity dilemma in information filtering.

    Science.gov (United States)

    Zeng, Wei; Zeng, An; Liu, Hao; Shang, Ming-Sheng; Zhang, Yi-Cheng

    2014-01-01

    Recommender systems are designed to assist individual users to navigate through the rapidly growing amount of information. One of the most successful recommendation techniques is the collaborative filtering, which has been extensively investigated and has already found wide applications in e-commerce. One of challenges in this algorithm is how to accurately quantify the similarities of user pairs and item pairs. In this paper, we employ the multidimensional scaling (MDS) method to measure the similarities between nodes in user-item bipartite networks. The MDS method can extract the essential similarity information from the networks by smoothing out noise, which provides a graphical display of the structure of the networks. With the similarity measured from MDS, we find that the item-based collaborative filtering algorithm can outperform the diffusion-based recommendation algorithms. Moreover, we show that this method tends to recommend unpopular items and increase the global diversification of the networks in long term.

  3. Similarity from multi-dimensional scaling: solving the accuracy and diversity dilemma in information filtering.

    Directory of Open Access Journals (Sweden)

    Wei Zeng

    Full Text Available Recommender systems are designed to assist individual users to navigate through the rapidly growing amount of information. One of the most successful recommendation techniques is the collaborative filtering, which has been extensively investigated and has already found wide applications in e-commerce. One of challenges in this algorithm is how to accurately quantify the similarities of user pairs and item pairs. In this paper, we employ the multidimensional scaling (MDS method to measure the similarities between nodes in user-item bipartite networks. The MDS method can extract the essential similarity information from the networks by smoothing out noise, which provides a graphical display of the structure of the networks. With the similarity measured from MDS, we find that the item-based collaborative filtering algorithm can outperform the diffusion-based recommendation algorithms. Moreover, we show that this method tends to recommend unpopular items and increase the global diversification of the networks in long term.

  4. Does one-to-one demonstration with insulin pads by health-care providers improves the insulin administration techniques among diabetic patients of a Tertiary Care Teaching Hospital in South India?

    Science.gov (United States)

    Kapoor, Urvasi; Ramasamy, Gomathi; Selvaraj, Kalaiselvi; Sahoo, Jaya Prakash; Kar, Sitanshu Sekhar

    2016-01-01

    The study was aimed to capture the effect of using injection pads as a tool in educating the diabetic patients who were on insulin. The attitude and practice of the patients in storage of insulin vials and disposal of insulin syringes were also assessed. A facility based Quasi-experimental study was carried out among the diabetic patients on insulin, attending diabetic clinic in endocrinology OPD in a tertiary care hospital, Puducherry. One to one intervention was given to the study participants or their attendants (who were involved in injecting insulin), by a trained investigator regarding all the steps of insulin administration. The insulin administration practices before and immediately after the intervention was assessed using a checklist. In total 91 patients were included for the study with mean (SD) age of 53.9 (10.6) years and of them 76% were females. The attitude and practices of the study participants, such as hand washing before handling insulin, checking the expiry date, storage of insulin, inspection of injection site, rolling and cleaning the vial, withdrawal of the syringe up to the required dose, pushing the plunger after inserting the syringe into the vial, checking and removal of air bubbles, cleaning the injection site and allow to dry and injection technique improved significantly after the intervention ( P insulin administration. The findings from the study can be applied in routine care and has to be explored further in diabetic patient management.

  5. Equivalence and Differences between Structural Equation Modeling and State-Space Modeling Techniques

    Science.gov (United States)

    Chow, Sy-Miin; Ho, Moon-ho R.; Hamaker, Ellen L.; Dolan, Conor V.

    2010-01-01

    State-space modeling techniques have been compared to structural equation modeling (SEM) techniques in various contexts but their unique strengths have often been overshadowed by their similarities to SEM. In this article, we provide a comprehensive discussion of these 2 approaches' similarities and differences through analytic comparisons and…

  6. Effects of similarity on environmental context cueing.

    Science.gov (United States)

    Smith, Steven M; Handy, Justin D; Angello, Genna; Manzano, Isabel

    2014-01-01

    Three experiments examined the prediction that context cues which are similar to study contexts can facilitate episodic recall, even if those cues are never seen before the recall test. Environmental context cueing effects have typically produced such small effect sizes that influences of moderating factors, such as the similarity between encoding and retrieval contexts, would be difficult to observe experimentally. Videos of environmental contexts, however, can be used to produce powerful context-dependent memory effects, particularly when only one memory target is associated with each video context, intentional item-context encoding is encouraged, and free recall tests are used. Experiment 1 showed that a not previously viewed video of the study context provided an effective recall cue, although it was not as effective as the originally viewed video context. Experiments 2 and 3 showed that videos of environments that were conceptually similar to encoding contexts (e.g., both were videos of ball field games) also cued recall, but not as well if the encoding contexts were given specific labels (e.g., "home run") incompatible with test contexts (e.g., a soccer scene). A fourth experiment that used incidental item-context encoding showed that video context reinstatement has a robust effect on paired associate memory, indicating that the video context reinstatement effect does not depend on interactive item-context encoding or free recall testing.

  7. Does one-to-one demonstration with insulin pads by health-care providers improves the insulin administration techniques among diabetic patients of a Tertiary Care Teaching Hospital in South India?

    Directory of Open Access Journals (Sweden)

    Urvasi Kapoor

    2016-01-01

    Full Text Available Objectives: The study was aimed to capture the effect of using injection pads as a tool in educating the diabetic patients who were on insulin. The attitude and practice of the patients in storage of insulin vials and disposal of insulin syringes were also assessed. Materials and Methods: A facility based Quasi-experimental study was carried out among the diabetic patients on insulin, attending diabetic clinic in endocrinology OPD in a tertiary care hospital, Puducherry. One to one intervention was given to the study participants or their attendants (who were involved in injecting insulin, by a trained investigator regarding all the steps of insulin administration. The insulin administration practices before and immediately after the intervention was assessed using a checklist. Results: In total 91 patients were included for the study with mean (SD age of 53.9 (10.6 years and of them 76% were females. The attitude and practices of the study participants, such as hand washing before handling insulin, checking the expiry date, storage of insulin, inspection of injection site, rolling and cleaning the vial, withdrawal of the syringe up to the required dose, pushing the plunger after inserting the syringe into the vial, checking and removal of air bubbles, cleaning the injection site and allow to dry and injection technique improved significantly after the intervention (P < 0.05. Conclusion: This study findings shows that using injection pads for educating patients helps them to practise better insulin administration. The findings from the study can be applied in routine care and has to be explored further in diabetic patient management.

  8. Similarity metrics for surgical process models.

    Science.gov (United States)

    Neumuth, Thomas; Loebe, Frank; Jannin, Pierre

    2012-01-01

    The objective of this work is to introduce a set of similarity metrics for comparing surgical process models (SPMs). SPMs are progression models of surgical interventions that support quantitative analyses of surgical activities, supporting systems engineering or process optimization. Five different similarity metrics are presented and proven. These metrics deal with several dimensions of process compliance in surgery, including granularity, content, time, order, and frequency of surgical activities. The metrics were experimentally validated using 20 clinical data sets each for cataract interventions, craniotomy interventions, and supratentorial tumor resections. The clinical data sets were controllably modified in simulations, which were iterated ten times, resulting in a total of 600 simulated data sets. The simulated data sets were subsequently compared to the original data sets to empirically assess the predictive validity of the metrics. We show that the results of the metrics for the surgical process models correlate significantly (pmetrics meet predictive validity. The clinical use of the metrics was exemplarily, as demonstrated by assessment of the learning curves of observers during surgical process model acquisition. Measuring similarity between surgical processes is a complex task. However, metrics for computing the similarity between surgical process models are needed in many uses in the field of medical engineering. These metrics are essential whenever two SPMs need to be compared, such as during the evaluation of technical systems, the education of observers, or the determination of surgical strategies. These metrics are key figures that provide a solid base for medical decisions, such as during validation of sensor systems for use in operating rooms in the future. Copyright © 2011 Elsevier B.V. All rights reserved.

  9. Experimental techniques; Techniques experimentales

    Energy Technology Data Exchange (ETDEWEB)

    Roussel-Chomaz, P. [GANIL CNRS/IN2P3, CEA/DSM, 14 - Caen (France)

    2007-07-01

    This lecture presents the experimental techniques, developed in the last 10 or 15 years, in order to perform a new class of experiments with exotic nuclei, where the reactions induced by these nuclei allow to get information on their structure. A brief review of the secondary beams production methods will be given, with some examples of facilities in operation or under project. The important developments performed recently on cryogenic targets will be presented. The different detection systems will be reviewed, both the beam detectors before the targets, and the many kind of detectors necessary to detect all outgoing particles after the reaction: magnetic spectrometer for the heavy fragment, detection systems for the target recoil nucleus, {gamma} detectors. Finally, several typical examples of experiments will be detailed, in order to illustrate the use of each detector either alone, or in coincidence with others. (author)

  10. Inequalities between similarities for numerical data

    NARCIS (Netherlands)

    Warrens, Matthijs J.

    Similarity measures are entities that can be used to quantify the similarity between two vectors with real numbers. We present inequalities between seven well known similarities. The inequalities are valid if the vectors contain non-negative real numbers.

  11. Privacy Preserving Similarity Based Text Retrieval through Blind Storage

    Directory of Open Access Journals (Sweden)

    Pinki Kumari

    2016-09-01

    Full Text Available Cloud computing is improving rapidly due to their more advantage and more data owners give interest to outsource their data into cloud storage for centralize their data. As huge files stored in the cloud storage, there is need to implement the keyword based search process to data user. At the same time to protect the privacy of data, encryption techniques are used for sensitive data, that encryption is done before outsourcing data to cloud server. But it is critical to search results in encryption data. In this system we propose similarity text retrieval from the blind storage blocks with encryption format. This system provides more security because of blind storage system. In blind storage system data is stored randomly on cloud storage.  In Existing Data Owner cannot encrypt the document data as it was done only at server end. Everyone can access the data as there was no private key concept applied to maintained privacy of the data. But In our proposed system, Data Owner can encrypt the data himself using RSA algorithm.  RSA is a public key-cryptosystem and it is widely used for sensitive data storage over Internet. In our system we use Text mining process for identifying the index files of user documents. Before encryption we also use NLP (Nature Language Processing technique to identify the keyword synonyms of data owner document. Here text mining process examines text word by word and collect literal meaning beyond the words group that composes the sentence. Those words are examined in API of word net so that only equivalent words can be identified for index file use. Our proposed system provides more secure and authorized way of recover the text in cloud storage with access control. Finally, our experimental result shows that our system is better than existing.

  12. Ranking and similarity of conventional, microwave and ultrasound element sequential extraction methods.

    Science.gov (United States)

    Relić, Dubravka; Héberger, Károly; Sakan, Sanja; Škrbić, Biljana; Popović, Aleksandar; Đorđević, Dragana

    2018-05-01

    This study aims to compare three extraction techniques of four sequential element extraction steps from soil and sediment samples that were taken from the location of the Pančevo petrochemical industry (Serbia). Elements were extracted using three different techniques: conventional, microwave and ultrasound extraction. A novel procedure - sum of the ranking differences (SRD) - was able to rank the techniques and elements, to see whether this method is a suitable tool to reveal the similarities and dissimilarities in element extraction techniques, provided that a proper ranking reference is available. The concentrations of the following elements Al, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, Si, Sn, Sr, V and Zn were determined through ICP OES. The different efficiencies and recovery values of element concentrations using each of the three extraction techniques were examined by the CRM BCR-701. By using SRD, we obtained a better separation between the different extraction techniques and steps when we rank their differences among the samples while lower separation was obtained according to analysed elements. Appling this method for ordering the elements could be useful for three purposes: (i) to find possible associations among the elements; (ii) to find possible elements that have outlier concentrations or (iii) detect differences in geochemical origin or behaviour of elements. Cross-validation of the SRD values in combination with cluster and principal component analysis revealed the same groups of extraction steps and techniques. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Popularity versus similarity in growing networks.

    Science.gov (United States)

    Papadopoulos, Fragkiskos; Kitsak, Maksim; Serrano, M Ángeles; Boguñá, Marián; Krioukov, Dmitri

    2012-09-27

    The principle that 'popularity is attractive' underlies preferential attachment, which is a common explanation for the emergence of scaling in growing networks. If new connections are made preferentially to more popular nodes, then the resulting distribution of the number of connections possessed by nodes follows power laws, as observed in many real networks. Preferential attachment has been directly validated for some real networks (including the Internet), and can be a consequence of different underlying processes based on node fitness, ranking, optimization, random walks or duplication. Here we show that popularity is just one dimension of attractiveness; another dimension is similarity. We develop a framework in which new connections optimize certain trade-offs between popularity and similarity, instead of simply preferring popular nodes. The framework has a geometric interpretation in which popularity preference emerges from local optimization. As opposed to preferential attachment, our optimization framework accurately describes the large-scale evolution of technological (the Internet), social (trust relationships between people) and biological (Escherichia coli metabolic) networks, predicting the probability of new links with high precision. The framework that we have developed can thus be used for predicting new links in evolving networks, and provides a different perspective on preferential attachment as an emergent phenomenon.

  14. Pharmacophore-based similarity scoring for DOCK.

    Science.gov (United States)

    Jiang, Lingling; Rizzo, Robert C

    2015-01-22

    Pharmacophore modeling incorporates geometric and chemical features of known inhibitors and/or targeted binding sites to rationally identify and design new drug leads. In this study, we have encoded a three-dimensional pharmacophore matching similarity (FMS) scoring function into the structure-based design program DOCK. Validation and characterization of the method are presented through pose reproduction, crossdocking, and enrichment studies. When used alone, FMS scoring dramatically improves pose reproduction success to 93.5% (∼20% increase) and reduces sampling failures to 3.7% (∼6% drop) compared to the standard energy score (SGE) across 1043 protein-ligand complexes. The combined FMS+SGE function further improves success to 98.3%. Crossdocking experiments using FMS and FMS+SGE scoring, for six diverse protein families, similarly showed improvements in success, provided proper pharmacophore references are employed. For enrichment, incorporating pharmacophores during sampling and scoring, in most cases, also yield improved outcomes when docking and rank-ordering libraries of known actives and decoys to 15 systems. Retrospective analyses of virtual screenings to three clinical drug targets (EGFR, IGF-1R, and HIVgp41) using X-ray structures of known inhibitors as pharmacophore references are also reported, including a customized FMS scoring protocol to bias on selected regions in the reference. Overall, the results and fundamental insights gained from this study should benefit the docking community in general, particularly researchers using the new FMS method to guide computational drug discovery with DOCK.

  15. Molecular Similarity Concepts for Informatics Applications.

    Science.gov (United States)

    Bajorath, Jürgen

    2017-01-01

    The assessment of small molecule similarity is a central task in chemoinformatics and medicinal chemistry. A variety of molecular representations and metrics are applied to computationally evaluate and quantify molecular similarity. A critically important aspect of molecular similarity analysis in chemoinformatics and pharmaceutical research is that one is typically not interested in quantifying the degree of structural or chemical similarity between compounds per se, but rather in extrapolating from molecular similarity to property similarity. In other words, one assumes that there is a correlation between calculated similarity and specific properties of small molecules including, first and foremost, biological activities. Although similarity is a priori a subjective concept, and difficult to quantify, it must computationally be assessed in a formally consistent manner. Otherwise, there is little utility of similarity calculations. Consistent treatment requires approximations to be made and the consideration of alternative computational similarity concepts, as discussed herein.

  16. A ligand's view of target similarity

    DEFF Research Database (Denmark)

    Garland, Stephen L; Gloriam, David E

    2011-01-01

    -finding and, potentially, to produce ligands for previously intractable receptors. Sequence motifs correlated with ligands can be applied in the design of target-specific focused libraries that are both efficient and cost-effective and should provide increased hit-rates over diversity screening. Furthermore...... shows with several examples how focusing on the binding site(s) has a clear advantage when it comes to establishing sequence-correlated pharmacological profiles. By organizing and comparing sequence and structural data it is possible to "borrow" SAR from similar targets to increase the speed of lead......, in the optimization phase, the binding motif approach offers the possibility to identify quickly the most likely off-target candidates to be chosen for selectivity screening, as well as potentially characterizing those pockets which may best be exploited for improved selectivity....

  17. Enhancing Media Personalization by Extracting Similarity Knowledge from Metadata

    DEFF Research Database (Denmark)

    Butkus, Andrius

    ) using Latent Semantic Analysis (one of the unsupervised machine learning techniques). It presents three separate cases to illustrate the similarity knowledge extraction from the metadata, where the emotional components in each case represents different abstraction levels – genres, synopsis and lyrics...... with many interrelated parts – recommendation engines, content metadata, contextual information and user profiles. In the center of any type of recommendation lies the notion of similarity. The most popular way to approach similarity is to look for the feature overlaps. This results often in recommending...... only “more of the same” type of content which does not necessarily lead to the meaningful personalization. Another way to approach similarity is to find a similar underlying meaning in the content. Aspects of meaning in media can be represented using Gardenfors Conceptual Spaces theory, which can...

  18. Surface science techniques

    CERN Document Server

    Bracco, Gianangelo

    2013-01-01

    The book describes the experimental techniques employed to study surfaces and interfaces. The emphasis is on the experimental method. Therefore all chapters start with an introduction of the scientific problem, the theory necessary to understand how the technique works and how to understand the results. Descriptions of real experimental setups, experimental results at different systems are given to show both the strength and the limits of the technique. In a final part the new developments and possible extensions of the techniques are presented. The included techniques provide microscopic as well as macroscopic information. They cover most of the techniques used in surface science.

  19. Cultural similarity, cultural competence, and nurse workforce diversity.

    Science.gov (United States)

    McGinnis, Sandra L; Brush, Barbara L; Moore, Jean

    2010-11-01

    Proponents of health workforce diversity argue that increasing the number of minority health care providers will enhance cultural similarity between patients and providers as well as the health system's capacity to provide culturally competent care. Measuring cultural similarity has been difficult, however, given that current benchmarks of workforce diversity categorize health workers by major racial/ethnic classifications rather than by cultural measures. This study examined the use of national racial/ethnic categories in both patient and registered nurse (RN) populations and found them to be a poor indicator of cultural similarity. Rather, we found that cultural similarity between RN and patient populations needs to be established at the level of local labor markets and broadened to include other cultural parameters such as country of origin, primary language, and self-identified ancestry. Only then can the relationship between cultural similarity and cultural competence be accurately determined and its outcomes measured.

  20. Long-Term Mean Wind Profiles Based on Similarity Theory

    DEFF Research Database (Denmark)

    Kelly, Mark C.; Gryning, Sven-Erik

    2010-01-01

    We provide general forms for long-term mean wind profiles from similarity-based wind profiles, beginning with a probabilistic adaptation of Monin–Obukhov similarity theory. We develop an analytical formulation for the stability distributions prevailing in the atmospheric surface layer, which...

  1. Implantation techniques of antitachycardia devices.

    Science.gov (United States)

    Furman, S; Brodman, R; Pannizzo, F; Fisher, J D

    1984-05-01

    Implantation of a defibrillator may be by a mixed technique of transvenous leads and subcostal thoracotomy. An alternative approach is placement of all defibrillator leads and possible pacemaker leads via median sternotomy. All sensing leads, either for a defibrillator or a pacemaker, should be bipolar to provide maximal rejection of interference signals. Interpretation of the electrogram requires analysis of the pathologic electrogram to distinguish it from the "normal" electrogram for that patient and may require several leads to determine the activation sequence which will allow diagnosis of a tachycardia in a fashion similar to that performed by a human observer.

  2. Asthma and COPD: Differences and Similarities

    Science.gov (United States)

    ... and COPD: differences and similarities Share | Asthma and COPD: Differences and Similarities This article has been reviewed ... or you could have Chronic Obstructive Pulmonary Disease (COPD) , such as emphysema or chronic bronchitis. Because asthma ...

  3. A quantitative comparison of the similarity between genes and geography in worldwide human populations.

    Science.gov (United States)

    Wang, Chaolong; Zöllner, Sebastian; Rosenberg, Noah A

    2012-08-01

    Multivariate statistical techniques such as principal components analysis (PCA) and multidimensional scaling (MDS) have been widely used to summarize the structure of human genetic variation, often in easily visualized two-dimensional maps. Many recent studies have reported similarity between geographic maps of population locations and MDS or PCA maps of genetic variation inferred from single-nucleotide polymorphisms (SNPs). However, this similarity has been evident primarily in a qualitative sense; and, because different multivariate techniques and marker sets have been used in different studies, it has not been possible to formally compare genetic variation datasets in terms of their levels of similarity with geography. In this study, using genome-wide SNP data from 128 populations worldwide, we perform a systematic analysis to quantitatively evaluate the similarity of genes and geography in different geographic regions. For each of a series of regions, we apply a Procrustes analysis approach to find an optimal transformation that maximizes the similarity between PCA maps of genetic variation and geographic maps of population locations. We consider examples in Europe, Sub-Saharan Africa, Asia, East Asia, and Central/South Asia, as well as in a worldwide sample, finding that significant similarity between genes and geography exists in general at different geographic levels. The similarity is highest in our examples for Asia and, once highly distinctive populations have been removed, Sub-Saharan Africa. Our results provide a quantitative assessment of the geographic structure of human genetic variation worldwide, supporting the view that geography plays a strong role in giving rise to human population structure.

  4. Similarity based approximate reasoning: fuzzy control

    NARCIS (Netherlands)

    Raha, S.; Hossain, A.; Ghosh, S.

    2008-01-01

    This paper presents an approach to similarity based approximate reasoning that elucidates the connection between similarity and existing approaches to inference in approximate reasoning methodology. A set of axioms is proposed to get a reasonable measure of similarity between two fuzzy sets. The

  5. Medical practices display power law behaviors similar to spoken languages.

    Science.gov (United States)

    Paladino, Jonathan D; Crooke, Philip S; Brackney, Christopher R; Kaynar, A Murat; Hotchkiss, John R

    2013-09-04

    Medical care commonly involves the apprehension of complex patterns of patient derangements to which the practitioner responds with patterns of interventions, as opposed to single therapeutic maneuvers. This complexity renders the objective assessment of practice patterns using conventional statistical approaches difficult. Combinatorial approaches drawn from symbolic dynamics are used to encode the observed patterns of patient derangement and associated practitioner response patterns as sequences of symbols. Concatenating each patient derangement symbol with the contemporaneous practitioner response symbol creates "words" encoding the simultaneous patient derangement and provider response patterns and yields an observed vocabulary with quantifiable statistical characteristics. A fundamental observation in many natural languages is the existence of a power law relationship between the rank order of word usage and the absolute frequency with which particular words are uttered. We show that population level patterns of patient derangement: practitioner intervention word usage in two entirely unrelated domains of medical care display power law relationships similar to those of natural languages, and that-in one of these domains-power law behavior at the population level reflects power law behavior at the level of individual practitioners. Our results suggest that patterns of medical care can be approached using quantitative linguistic techniques, a finding that has implications for the assessment of expertise, machine learning identification of optimal practices, and construction of bedside decision support tools.

  6. Therapy Provider Phase Information

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Therapy Provider Phase Information dataset is a tool for providers to search by their National Provider Identifier (NPI) number to determine their phase for...

  7. Similarity Structure of Wave-Collapse

    DEFF Research Database (Denmark)

    Rypdal, Kristoffer; Juul Rasmussen, Jens; Thomsen, Kenneth

    1985-01-01

    Similarity transformations of the cubic Schrödinger equation (CSE) are investigated. The transformations are used to remove the explicit time variation in the CSE and reduce it to differential equations in the spatial variables only. Two different methods for similarity reduction are employed...... and the significance of similarity in the evolution of a collapsing wave packet is investigated. Numerical solutions in radial symmetry demonstrate that the similarity behaviour is local in space and time, and that some similarity solutions must be classified as improper solutions. The nature of the collapsing...

  8. Determining the semantic similarities among Gene Ontology terms.

    Science.gov (United States)

    Taha, Kamal

    2013-05-01

    We present in this paper novel techniques that determine the semantic relationships among GeneOntology (GO) terms. We implemented these techniques in a prototype system called GoSE, which resides between user application and GO database. Given a set S of GO terms, GoSE would return another set S' of GO terms, where each term in S' is semantically related to each term in S. Most current research is focused on determining the semantic similarities among GO ontology terms based solely on their IDs and proximity to one another in the GO graph structure, while overlooking the contexts of the terms, which may lead to erroneous results. The context of a GO term T is the set of other terms, whose existence in the GO graph structure is dependent on T. We propose novel techniques that determine the contexts of terms based on the concept of existence dependency. We present a stack-based sort-merge algorithm employing these techniques for determining the semantic similarities among GO terms.We evaluated GoSE experimentally and compared it with three existing methods. The results of measuring the semantic similarities among genes in KEGG and Pfam pathways retrieved from the DBGET and Sanger Pfam databases, respectively, have shown that our method outperforms the other three methods in recall and precision.

  9. Musical structure analysis using similarity matrix and dynamic programming

    Science.gov (United States)

    Shiu, Yu; Jeong, Hong; Kuo, C.-C. Jay

    2005-10-01

    Automatic music segmentation and structure analysis from audio waveforms based on a three-level hierarchy is examined in this research, where the three-level hierarchy includes notes, measures and parts. The pitch class profile (PCP) feature is first extracted at the note level. Then, a similarity matrix is constructed at the measure level, where a dynamic time warping (DTW) technique is used to enhance the similarity computation by taking the temporal distortion of similar audio segments into account. By processing the similarity matrix, we can obtain a coarse-grain music segmentation result. Finally, dynamic programming is applied to the coarse-grain segments so that a song can be decomposed into several major parts such as intro, verse, chorus, bridge and outro. The performance of the proposed music structure analysis system is demonstrated for pop and rock music.

  10. Semantic Similarity Assessment of Volunteered Geographic Information

    Directory of Open Access Journals (Sweden)

    Maythm M. Albakri

    2017-01-01

    Full Text Available The recent development in communication technologies between individuals allows for the establishment of more informal collaborative map data projects which are called volunteered geographic information (VGI. These projects, such as OpenStreetMap (OSM project, seek to create free alternative maps which let users add or input new materials to the data of others. The information of different VGI data sources is often not compliant to any standard and each organization is producing a dataset at various level of richness. In this research the assessment of semantic data quality provided by web sources, e.g. OSM will depend on a comparison with the information from standard sources. This will include the validity of semantic accuracy as one of the most important parameter of spatial data quality parameters. Semantic similarity testing covered feature classification, in effect comparing possible categories (legend classes and actual attributes attached to features. This will be achieved by developing a tool, using Matlab programming language, for analysing and examining OSM semantic accuracy. To identify the strength of semantic accuracy assessment strategy, there are many factors should be considered. For instance, the confusion matrix of feature classifications can be assessed, and different statistical tests should be passed. The results revealed good semantic accuracy of OSM datasets.

  11. Dismantling techniques

    International Nuclear Information System (INIS)

    Wiese, E.

    1998-01-01

    Most of the dismantling techniques used in a Decontamination and Dismantlement (D and D) project are taken from conventional demolition practices. Some modifications to the techniques are made to limit exposure to the workers or to lessen the spread of contamination to the work area. When working on a D and D project, it is best to keep the dismantling techniques and tools as simple as possible. The workers will be more efficient and safer using techniques that are familiar to them. Prior experience with the technique or use of mock-ups is the best way to keep workers safe and to keep the project on schedule

  12. Similar speaker recognition using nonlinear analysis

    International Nuclear Information System (INIS)

    Seo, J.P.; Kim, M.S.; Baek, I.C.; Kwon, Y.H.; Lee, K.S.; Chang, S.W.; Yang, S.I.

    2004-01-01

    Speech features of the conventional speaker identification system, are usually obtained by linear methods in spectral space. However, these methods have the drawback that speakers with similar voices cannot be distinguished, because the characteristics of their voices are also similar in spectral space. To overcome the difficulty in linear methods, we propose to use the correlation exponent in the nonlinear space as a new feature vector for speaker identification among persons with similar voices. We show that our proposed method surprisingly reduces the error rate of speaker identification system to speakers with similar voices

  13. A Quantum-Based Similarity Method in Virtual Screening

    Directory of Open Access Journals (Sweden)

    Mohammed Mumtaz Al-Dabbagh

    2015-10-01

    Full Text Available One of the most widely-used techniques for ligand-based virtual screening is similarity searching. This study adopted the concepts of quantum mechanics to present as state-of-the-art similarity method of molecules inspired from quantum theory. The representation of molecular compounds in mathematical quantum space plays a vital role in the development of quantum-based similarity approach. One of the key concepts of quantum theory is the use of complex numbers. Hence, this study proposed three various techniques to embed and to re-represent the molecular compounds to correspond with complex numbers format. The quantum-based similarity method that developed in this study depending on complex pure Hilbert space of molecules called Standard Quantum-Based (SQB. The recall of retrieved active molecules were at top 1% and top 5%, and significant test is used to evaluate our proposed methods. The MDL drug data report (MDDR, maximum unbiased validation (MUV and Directory of Useful Decoys (DUD data sets were used for experiments and were represented by 2D fingerprints. Simulated virtual screening experiment show that the effectiveness of SQB method was significantly increased due to the role of representational power of molecular compounds in complex numbers forms compared to Tanimoto benchmark similarity measure.

  14. Protontherapy versus carbon ion therapy advantages, disadvantages and similarities

    CERN Document Server

    d’Ávila Nunes, Marcos

    2015-01-01

    This book presents a comparison analysis of two cancer treatment therapies: carbon ion therapy and protontherapy. It is divided in 5 sections. The first ones gives the reader a brief history of Radiotherapy and types of radiation. In the second section, the techniques and equipments, including new ones in development such as Cyclinac , Laser and DWA, are described. The third section describes biophysical (such as stopping power and LET) and biological (such as RBE and OER) properties, the fundamental experiments and clinical area. The fourth section presents models and the fifth section compares both techniques, showing advantages and disadvantages of each, and their similarities.

  15. A Novel Approach For Syntactic Similarity Between Two Short Text

    Directory of Open Access Journals (Sweden)

    Anterpreet Kaur

    2015-06-01

    Full Text Available ABSTRACT Syntactic similarity is an important activity in the area of high field of text documents data mining natural language processing information retrieval. Natural language processing NLP is the intelligent machine where its ability is to translate the text into natural language such as English and other computer language such as c. Web mining used for task such as document clustering community mining etc to performed on web. However to find the similarity between the two documents is the difficult task. So with increasing scope in NLP require technique for dealing with many aspects of language in particular syntax semantics and paradigms.

  16. Providers? perspectives on collaboration

    OpenAIRE

    Bruner, Patricia; Waite, Roberta; Davey, Maureen P

    2011-01-01

    Objective: Changes in models of health care are required to better meet the needs of diverse, underserved patient populations. Collaboration among providers is one way to promote accessible, comprehensive and continuous care in healthcare organizations. This paper describes the quantitative findings from two time points that examined providers' views of collaboration among a sample of diverse personnel (e.g. clinical nurses, social workers, dental providers, mental health providers, clerical ...

  17. Industrial technique

    International Nuclear Information System (INIS)

    Jabsen, F.S.

    1975-01-01

    An illustrative embodiment of the invention discloses a technique for disassembling a nuclear reactor fuel element without destroying the individual fuel pins and other structural components from which the element is assembled. A traveling bridge and trolley that span a water-filled spent fuel storage pool support a strongback. The strongback is under water and provides a working surface on which the spent fuel element is placed for inspection and for the manipulation that is associated with disassembly and assembly. To remove, in a non-destructive manner, the grids that hold the fuel pins in the proper relative positions within the element, bars are inserted through apertures in the grids with the aid of special tools. These bars are rotated to flex the adjacent grid walls and, in this way relax the physical engagement between protruding portions of the grid walls and the associated fuel pins. With the grid structure so flexed to relax the physical grip on the individual fuel pins, these pins can be withdrawn for inspection or replacement as necessary without imposing a need to destroy fuel element components. (U.S.)

  18. Clustering by reordering of similarity and Laplacian matrices: Application to galaxy clusters

    Science.gov (United States)

    Mahmoud, E.; Shoukry, A.; Takey, A.

    2018-04-01

    Similarity metrics, kernels and similarity-based algorithms have gained much attention due to their increasing applications in information retrieval, data mining, pattern recognition and machine learning. Similarity Graphs are often adopted as the underlying representation of similarity matrices and are at the origin of known clustering algorithms such as spectral clustering. Similarity matrices offer the advantage of working in object-object (two-dimensional) space where visualization of clusters similarities is available instead of object-features (multi-dimensional) space. In this paper, sparse ɛ-similarity graphs are constructed and decomposed into strong components using appropriate methods such as Dulmage-Mendelsohn permutation (DMperm) and/or Reverse Cuthill-McKee (RCM) algorithms. The obtained strong components correspond to groups (clusters) in the input (feature) space. Parameter ɛi is estimated locally, at each data point i from a corresponding narrow range of the number of nearest neighbors. Although more advanced clustering techniques are available, our method has the advantages of simplicity, better complexity and direct visualization of the clusters similarities in a two-dimensional space. Also, no prior information about the number of clusters is needed. We conducted our experiments on two and three dimensional, low and high-sized synthetic datasets as well as on an astronomical real-dataset. The results are verified graphically and analyzed using gap statistics over a range of neighbors to verify the robustness of the algorithm and the stability of the results. Combining the proposed algorithm with gap statistics provides a promising tool for solving clustering problems. An astronomical application is conducted for confirming the existence of 45 galaxy clusters around the X-ray positions of galaxy clusters in the redshift range [0.1..0.8]. We re-estimate the photometric redshifts of the identified galaxy clusters and obtain acceptable values

  19. Similarity indices I: what do they measure

    International Nuclear Information System (INIS)

    Johnston, J.W.

    1976-11-01

    A method for estimating the effects of environmental effusions on ecosystems is described. The characteristics of 25 similarity indices used in studies of ecological communities were investigated. The type of data structure, to which these indices are frequently applied, was described as consisting of vectors of measurements on attributes (species) observed in a set of samples. A general similarity index was characterized as the result of a two-step process defined on a pair of vectors. In the first step an attribute similarity score is obtained for each attribute by comparing the attribute values observed in the pair of vectors. The result is a vector of attribute similarity scores. These are combined in the second step to arrive at the similarity index. The operation in the first step was characterized as a function, g, defined on pairs of attribute values. The second operation was characterized as a function, F, defined on the vector of attribute similarity scores from the first step. Usually, F was a simple sum or weighted sum of the attribute similarity scores. It is concluded that similarity indices should not be used as the test statistic to discriminate between two ecological communities

  20. Molecular quantum similarity using conceptual DFT descriptors

    Indian Academy of Sciences (India)

    This paper reports a Molecular Quantum Similarity study for a set of congeneric steroid molecules, using as basic similarity descriptors electron density ρ (r), shape ... Department of Inorganic and Physical Chemistry, Ghent University, Krijgslaan 281, B-9000 Gent, Belgium; Institute of Computational Chemistry, University of ...

  1. Learning deep similarity in fundus photography

    Science.gov (United States)

    Chudzik, Piotr; Al-Diri, Bashir; Caliva, Francesco; Ometto, Giovanni; Hunter, Andrew

    2017-02-01

    Similarity learning is one of the most fundamental tasks in image analysis. The ability to extract similar images in the medical domain as part of content-based image retrieval (CBIR) systems has been researched for many years. The vast majority of methods used in CBIR systems are based on hand-crafted feature descriptors. The approximation of a similarity mapping for medical images is difficult due to the big variety of pixel-level structures of interest. In fundus photography (FP) analysis, a subtle difference in e.g. lesions and vessels shape and size can result in a different diagnosis. In this work, we demonstrated how to learn a similarity function for image patches derived directly from FP image data without the need of manually designed feature descriptors. We used a convolutional neural network (CNN) with a novel architecture adapted for similarity learning to accomplish this task. Furthermore, we explored and studied multiple CNN architectures. We show that our method can approximate the similarity between FP patches more efficiently and accurately than the state-of- the-art feature descriptors, including SIFT and SURF using a publicly available dataset. Finally, we observe that our approach, which is purely data-driven, learns that features such as vessels calibre and orientation are important discriminative factors, which resembles the way how humans reason about similarity. To the best of authors knowledge, this is the first attempt to approximate a visual similarity mapping in FP.

  2. Similarity indices I: what do they measure.

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, J.W.

    1976-11-01

    A method for estimating the effects of environmental effusions on ecosystems is described. The characteristics of 25 similarity indices used in studies of ecological communities were investigated. The type of data structure, to which these indices are frequently applied, was described as consisting of vectors of measurements on attributes (species) observed in a set of samples. A general similarity index was characterized as the result of a two-step process defined on a pair of vectors. In the first step an attribute similarity score is obtained for each attribute by comparing the attribute values observed in the pair of vectors. The result is a vector of attribute similarity scores. These are combined in the second step to arrive at the similarity index. The operation in the first step was characterized as a function, g, defined on pairs of attribute values. The second operation was characterized as a function, F, defined on the vector of attribute similarity scores from the first step. Usually, F was a simple sum or weighted sum of the attribute similarity scores. It is concluded that similarity indices should not be used as the test statistic to discriminate between two ecological communities.

  3. Mining Diagnostic Assessment Data for Concept Similarity

    Science.gov (United States)

    Madhyastha, Tara; Hunt, Earl

    2009-01-01

    This paper introduces a method for mining multiple-choice assessment data for similarity of the concepts represented by the multiple choice responses. The resulting similarity matrix can be used to visualize the distance between concepts in a lower-dimensional space. This gives an instructor a visualization of the relative difficulty of concepts…

  4. Similarity measure computation of convex polyhedra revisited

    NARCIS (Netherlands)

    Roerdink, Jos B.T.M.; Bekker, Henk

    2001-01-01

    We study the computation of rotation-invariant similarity measures of convex polyhedra, based on Minkowski’s theory of mixed volumes. To compute the similarity measure, a (mixed) volume functional has to be minimized over a number of critical orientations of these polyhedra. These critical

  5. Asymmetric similarity-weighted ensembles for image segmentation

    DEFF Research Database (Denmark)

    Cheplygina, V.; Van Opbroek, A.; Ikram, M. A.

    2016-01-01

    Supervised classification is widely used for image segmentation. To work effectively, these techniques need large amounts of labeled training data, that is representative of the test data. Different patient groups, different scanners or different scanning protocols can lead to differences between...... the images, thus representative data might not be available. Transfer learning techniques can be used to account for these differences, thus taking advantage of all the available data acquired with different protocols. We investigate the use of classifier ensembles, where each classifier is weighted...... according to the similarity between the data it is trained on, and the data it needs to segment. We examine 3 asymmetric similarity measures that can be used in scenarios where no labeled data from a newly introduced scanner or scanning protocol is available. We show that the asymmetry is informative...

  6. Semantic similarity: normative ratings for 185 Spanish noun triplets.

    Science.gov (United States)

    Moldovan, Cornelia D; Ferré, Pilar; Demestre, Josep; Sánchez-Casas, Rosa

    2015-09-01

    The present study introduces the first Spanish database with normative ratings of semantic similarity for 185 word triplets. Each word triplet is constituted by a target word (e.g., guisante [pea]) and two semantically related and nonassociatively related words: a word highly related in meaning to the target (e.g., judía [bean]), and a word less related in meaning to the target (e.g., patata [potato]). The degree of meaning similarity was assessed by 332 participants by using a semantic similarity rating task on a 9-point scale. Pairs having a value of semantic similarity ranging from 5 to 9 were classified as being more semantically related, whereas those with values ranging from 2 to 4.99 were considered as being less semantically related. The relative distance between the two pairs for the same target ranged from 0.48 to 5.07 points. Mean comparisons revealed that participants rated the more similar words as being significantly more similar in meaning to the target word than were the less similar words. In addition to the semantic similarity norms, values of concreteness and familiarity of each word in a triplet are provided. The present database can be a very useful tool for scientists interested in designing experiments to examine the role of semantics in language processing. Since the variable of semantic similarity includes a wide range of values, it can be used as either a continuous or a dichotomous variable. The full database is available in the supplementary materials.

  7. Computational prediction of drug-drug interactions based on drugs functional similarities.

    Science.gov (United States)

    Ferdousi, Reza; Safdari, Reza; Omidi, Yadollah

    2017-06-01

    Therapeutic activities of drugs are often influenced by co-administration of drugs that may cause inevitable drug-drug interactions (DDIs) and inadvertent side effects. Prediction and identification of DDIs are extremely vital for the patient safety and success of treatment modalities. A number of computational methods have been employed for the prediction of DDIs based on drugs structures and/or functions. Here, we report on a computational method for DDIs prediction based on functional similarity of drugs. The model was set based on key biological elements including carriers, transporters, enzymes and targets (CTET). The model was applied for 2189 approved drugs. For each drug, all the associated CTETs were collected, and the corresponding binary vectors were constructed to determine the DDIs. Various similarity measures were conducted to detect DDIs. Of the examined similarity methods, the inner product-based similarity measures (IPSMs) were found to provide improved prediction values. Altogether, 2,394,766 potential drug pairs interactions were studied. The model was able to predict over 250,000 unknown potential DDIs. Upon our findings, we propose the current method as a robust, yet simple and fast, universal in silico approach for identification of DDIs. We envision that this proposed method can be used as a practical technique for the detection of possible DDIs based on the functional similarities of drugs. Copyright © 2017. Published by Elsevier Inc.

  8. Local indices for similarity analysis (LISA)-a 3D-QSAR formalism based on local molecular similarity.

    Science.gov (United States)

    Verma, Jitender; Malde, Alpeshkumar; Khedkar, Santosh; Iyer, Radhakrishnan; Coutinho, Evans

    2009-12-01

    A simple quantitative structure activity relationship (QSAR) approach termed local indices for similarity analysis (LISA) has been developed. In this technique, the global molecular similarity is broken up as local similarity at each grid point surrounding the molecules and is used as a QSAR descriptor. In this way, a view of the molecular sites permitting favorable and rational changes to enhance activity is obtained. The local similarity index, calculated on the basis of Petke's formula, segregates the regions into "equivalent", "favored similar", and "disfavored similar" (alternatively "favored dissimilar") potentials with respect to a reference molecule in the data set. The method has been tested on three large and diverse data sets-thrombin, glycogen phosphorylase b, and thermolysin inhibitors. The QSAR models derived using genetic algorithm incorporated partial least square analysis statistics are found to be comparable to the ones obtained by the standard three-dimensional (3D)-QSAR methods, such as comparative molecular field analysis and comparative molecular similarity indices analysis. The graphical interpretation of the LISA models is straightforward, and the outcome of the models corroborates well with literature data. The LISA models give insight into the binding mechanisms of the ligand with the enzyme and allow fine-tuning of the molecules at the local level to improve their activity.

  9. Flash Infrared Thermography Contrast Data Analysis Technique

    Science.gov (United States)

    Koshti, Ajay

    2014-01-01

    This paper provides information on an IR Contrast technique that involves extracting normalized contrast versus time evolutions from the flash thermography inspection infrared video data. The analysis calculates thermal measurement features from the contrast evolution. In addition, simulation of the contrast evolution is achieved through calibration on measured contrast evolutions from many flat-bottom holes in the subject material. The measurement features and the contrast simulation are used to evaluate flash thermography data in order to characterize delamination-like anomalies. The thermal measurement features relate to the anomaly characteristics. The contrast evolution simulation is matched to the measured contrast evolution over an anomaly to provide an assessment of the anomaly depth and width which correspond to the depth and diameter of the equivalent flat-bottom hole (EFBH) similar to that used as input to the simulation. A similar analysis, in terms of diameter and depth of an equivalent uniform gap (EUG) providing a best match with the measured contrast evolution, is also provided. An edge detection technique called the half-max is used to measure width and length of the anomaly. Results of the half-max width and the EFBH/EUG diameter are compared to evaluate the anomaly. The information provided here is geared towards explaining the IR Contrast technique. Results from a limited amount of validation data on reinforced carbon-carbon (RCC) hardware are included in this paper.

  10. Measure of Node Similarity in Multilayer Networks.

    Directory of Open Access Journals (Sweden)

    Anders Mollgaard

    Full Text Available The weight of links in a network is often related to the similarity of the nodes. Here, we introduce a simple tunable measure for analysing the similarity of nodes across different link weights. In particular, we use the measure to analyze homophily in a group of 659 freshman students at a large university. Our analysis is based on data obtained using smartphones equipped with custom data collection software, complemented by questionnaire-based data. The network of social contacts is represented as a weighted multilayer network constructed from different channels of telecommunication as well as data on face-to-face contacts. We find that even strongly connected individuals are not more similar with respect to basic personality traits than randomly chosen pairs of individuals. In contrast, several socio-demographics variables have a significant degree of similarity. We further observe that similarity might be present in one layer of the multilayer network and simultaneously be absent in the other layers. For a variable such as gender, our measure reveals a transition from similarity between nodes connected with links of relatively low weight to dis-similarity for the nodes connected by the strongest links. We finally analyze the overlap between layers in the network for different levels of acquaintanceships.

  11. Notions of similarity for computational biology models

    KAUST Repository

    Waltemath, Dagmar

    2016-03-21

    Computational models used in biology are rapidly increasing in complexity, size, and numbers. To build such large models, researchers need to rely on software tools for model retrieval, model combination, and version control. These tools need to be able to quantify the differences and similarities between computational models. However, depending on the specific application, the notion of similarity may greatly vary. A general notion of model similarity, applicable to various types of models, is still missing. Here, we introduce a general notion of quantitative model similarities, survey the use of existing model comparison methods in model building and management, and discuss potential applications of model comparison. To frame model comparison as a general problem, we describe a theoretical approach to defining and computing similarities based on different model aspects. Potentially relevant aspects of a model comprise its references to biological entities, network structure, mathematical equations and parameters, and dynamic behaviour. Future similarity measures could combine these model aspects in flexible, problem-specific ways in order to mimic users\\' intuition about model similarity, and to support complex model searches in databases.

  12. Information Extraction Using Distant Supervision and Semantic Similarities

    Directory of Open Access Journals (Sweden)

    PARK, Y.

    2016-02-01

    Full Text Available Information extraction is one of the main research tasks in natural language processing and text mining that extracts useful information from unstructured sentences. Information extraction techniques include named entity recognition, relation extraction, and co-reference resolution. Among them, relation extraction refers to a task that extracts semantic relations between entities such as personal and geographic names in documents. This is an important research area, which is used in knowledge base construction and question and answering systems. This study presents relation extraction using a distant supervision learning technique among semi-supervised learning methods, which have been spotlighted in recent years to reduce human manual work and costs required for supervised learning. That is, this study proposes a method that can improve relation extraction by improving a distant supervision learning technique by applying a clustering method to create a learning corpus and semantic analysis for relation extraction that is difficult to identify using existing distant supervision. Through comparison experiments of various semantic similarity comparison methods, similarity calculation methods that are useful to relation extraction using distant supervision are searched, and a large number of accurate relation triples can be extracted using the proposed structural advantages and semantic similarity comparison.

  13. IntelliGO: a new vector-based semantic similarity measure including annotation origin

    Directory of Open Access Journals (Sweden)

    Devignes Marie-Dominique

    2010-12-01

    Full Text Available Abstract Background The Gene Ontology (GO is a well known controlled vocabulary describing the biological process, molecular function and cellular component aspects of gene annotation. It has become a widely used knowledge source in bioinformatics for annotating genes and measuring their semantic similarity. These measures generally involve the GO graph structure, the information content of GO aspects, or a combination of both. However, only a few of the semantic similarity measures described so far can handle GO annotations differently according to their origin (i.e. their evidence codes. Results We present here a new semantic similarity measure called IntelliGO which integrates several complementary properties in a novel vector space model. The coefficients associated with each GO term that annotates a given gene or protein include its information content as well as a customized value for each type of GO evidence code. The generalized cosine similarity measure, used for calculating the dot product between two vectors, has been rigorously adapted to the context of the GO graph. The IntelliGO similarity measure is tested on two benchmark datasets consisting of KEGG pathways and Pfam domains grouped as clans, considering the GO biological process and molecular function terms, respectively, for a total of 683 yeast and human genes and involving more than 67,900 pair-wise comparisons. The ability of the IntelliGO similarity measure to express the biological cohesion of sets of genes compares favourably to four existing similarity measures. For inter-set comparison, it consistently discriminates between distinct sets of genes. Furthermore, the IntelliGO similarity measure allows the influence of weights assigned to evidence codes to be checked. Finally, the results obtained with a complementary reference technique give intermediate but correct correlation values with the sequence similarity, Pfam, and Enzyme classifications when compared to

  14. Natural cohorts: family similarity in adult cognition.

    Science.gov (United States)

    Schaie, K W; Plomin, R; Willis, S L; Gruber-Baldini, A; Dutta, R

    1991-01-01

    We now return to the sets of hypotheses formulated in the introductory section to explore how the findings reported above bear on these propositions. Our first hypothesis dealt with whether family similarity could be observed in adulthood and whether there were differing ability patterns in such similarity. Significant family similarities were observed for our total sample for all ability measures, except Perceptual Speed, and for the cognitive style measures. The magnitude of correlations for the ability measures are comparable for those found between young adults and their children (DeFries et al., 1976). Similar to the DeFries study, we also found differences in resemblance across subsets. For example, same gender pairs showed higher correlations on Verbal Meaning, Number, and Word Fluency but opposite-gender pairs on Spatial Orientation, Inductive Reasoning, and Motor-Cognitive Flexibility. Also, greater similarity was found between mother-offspring pairs than father-offspring pairs on Inductive Reasoning and Psychomotor Speed. Moreover, higher parent-offspring correlations were found for daughters than for sons, suggesting at least the possibility that females may experience greater shared environmental influences than males. Our first hypothesis also argued for the possible effect of early shared environment upon offspring performance on Verbal Meaning and Word Fluency. After age adjustment, these were indeed the abilities that showed the highest parent-offspring similarity. Our second hypothesis proposed that if shared environmental influences are relatively unimportant in adulthood, then similarity within parent-offspring pairs should remain reasonably constant in adulthood across time and age. Our examination of this issue with a longitudinal sample ranging over a 21-year period strongly supports this proposition for all of those variables that displayed significant parent-offspring correlations. Indeed, parent-offspring correlations measured at

  15. A Similarity Search Using Molecular Topological Graphs

    Directory of Open Access Journals (Sweden)

    Yoshifumi Fukunishi

    2009-01-01

    Full Text Available A molecular similarity measure has been developed using molecular topological graphs and atomic partial charges. Two kinds of topological graphs were used. One is the ordinary adjacency matrix and the other is a matrix which represents the minimum path length between two atoms of the molecule. The ordinary adjacency matrix is suitable to compare the local structures of molecules such as functional groups, and the other matrix is suitable to compare the global structures of molecules. The combination of these two matrices gave a similarity measure. This method was applied to in silico drug screening, and the results showed that it was effective as a similarity measure.

  16. Similarity-based pattern analysis and recognition

    CERN Document Server

    Pelillo, Marcello

    2013-01-01

    This accessible text/reference presents a coherent overview of the emerging field of non-Euclidean similarity learning. The book presents a broad range of perspectives on similarity-based pattern analysis and recognition methods, from purely theoretical challenges to practical, real-world applications. The coverage includes both supervised and unsupervised learning paradigms, as well as generative and discriminative models. Topics and features: explores the origination and causes of non-Euclidean (dis)similarity measures, and how they influence the performance of traditional classification alg

  17. Detection of a reservoir water level using shape similarity metrics

    Science.gov (United States)

    Pipitone, Claudia; Maltese, Antonino; Dardanelli, Gino; Capodici, Fulvio; Lo Brutto, Mauro; La Loggia, Goffredo

    2017-10-01

    The matching between reservoirs' water edge and digital elevation model's (DEM) contour lines allowed determining the water level at the acquisition date of satellite images. A preliminary study was conducted on the Castello dam (Magazzolo Lake), between Alessandria della Rocca and Bivona (Agrigento, south-Italy). The accuracy assessment of the technique was than evaluated from the comparison between classified and reference objects using similarity metrics about the shape, theme, edge and position, through the plugin STEP of open source software GIS. Moreover, an independent GIS technique was implemented to evaluate the water level, based on a distances' array between existing contour lines and nodes extracted from vectorised classification images. Results have shown the potentiality of the techniques when applied on an ideal case; advantages and disadvantages when the images are characterized by clear sky, and limits when images are acquired during not ideal atmospheric conditions.

  18. Acquired Techniques

    DEFF Research Database (Denmark)

    Lunde Nielsen, Espen; Halse, Karianne

    2013-01-01

    Acquired Techniques - a Leap into the Archive, at Aarhus School of Architecture. In collaboration with Karianne Halse, James Martin and Mika K. Friis. Following the footsteps of past travelers this is a journey into tools and techniques of the architectural process. The workshop will focus upon...

  19. Providing free autopoweroff plugs

    DEFF Research Database (Denmark)

    Jensen, Carsten Lynge; Hansen, Lars Gårn; Fjordbak, Troels

    2012-01-01

    Experimental evidence of the effect of providing households with cheap energy saving technology is sparse. We present results from a field experiment in which autopoweroff plugs were provided free of charge to randomly selected households. We use propensity score matching to find treatment effects...

  20. Provider Health and Wellness.

    Science.gov (United States)

    Nanda, Anil; Wasan, Anita; Sussman, James

    Provider health and wellness is a significant issue and can impact patient care, including patient satisfaction, quality of care, medical errors, malpractice risk, as well as provider and office staff turnover and early retirement. Health and wellness encompasses various areas including burnout, depression, divorce, and suicide and affects providers of all specialties and at all levels of training. Providers deal with many everyday stresses, including electronic health records, office politics, insurance and billing issues, dissatisfied patients, and their own personal and family issues. Approximately half of all physicians suffer from burnout, and the rate of burnout among physicians of all specialties is increasing. An important first step in dealing with burnout is recognition and then seeking assistance. Strategies to prevent and treat burnout include increasing provider resiliency as well as implementing practical changes in the everyday practice of medicine. There is currently very little data regarding health and wellness specifically in the field of allergy and immunology, and studies are necessary to determine the prevalence of burnout and related issues in this field. Many medical specialties as well as state and national medical associations have health and wellness committees and other resources, which are essential for providers. Health and wellness programs should be introduced early in a provider's training and continued throughout a provider's career. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  1. Building Service Provider Capabilities

    DEFF Research Database (Denmark)

    Brandl, Kristin; Jaura, Manya; Ørberg Jensen, Peter D.

    In this paper we study whether and how the interaction between clients and the service providers contributes to the development of capabilities in service provider firms. In situations where such a contribution occurs, we analyze how different types of activities in the production process of the ...

  2. Similar associations of tooth microwear and morphology indicate similar diet across marsupial and placental mammals.

    Directory of Open Access Journals (Sweden)

    Hilary B Christensen

    Full Text Available Low-magnification microwear techniques have been used effectively to infer diets within many unrelated mammalian orders, but the extent to which patterns are comparable among such different groups, including long extinct mammal lineages, is unknown. Microwear patterns between ecologically equivalent placental and marsupial mammals are found to be statistically indistinguishable, indicating that microwear can be used to infer diet across the mammals. Microwear data were compared to body size and molar shearing crest length in order to develop a system to distinguish the diet of mammals. Insectivores and carnivores were difficult to distinguish from herbivores using microwear alone, but combining microwear data with body size estimates and tooth morphology provides robust dietary inferences. This approach is a powerful tool for dietary assessment of fossils from extinct lineages and from museum specimens of living species where field study would be difficult owing to the animal's behavior, habitat, or conservation status.

  3. Media segmentation using self-similarity decomposition

    Science.gov (United States)

    Foote, Jonathan T.; Cooper, Matthew L.

    2003-01-01

    We present a framework for analyzing the structure of digital media streams. Though our methods work for video, text, and audio, we concentrate on detecting the structure of digital music files. In the first step, spectral data is used to construct a similarity matrix calculated from inter-frame spectral similarity.The digital audio can be robustly segmented by correlating a kernel along the diagonal of the similarity matrix. Once segmented, spectral statistics of each segment are computed. In the second step,segments are clustered based on the self-similarity of their statistics. This reveals the structure of the digital music in a set of segment boundaries and labels. Finally, the music is summarized by selecting clusters with repeated segments throughout the piece. The summaries can be customized for various applications based on the structure of the original music.

  4. Abundance estimation of spectrally similar minerals

    CSIR Research Space (South Africa)

    Debba, Pravesh

    2009-07-01

    Full Text Available This paper evaluates a spectral unmixing method for estimating the partial abundance of spectrally similar minerals in complex mixtures. The method requires formulation of a linear function of individual spectra of individual minerals. The first...

  5. Similarities in Becoming: Transsexuals and Adolescents.

    Science.gov (United States)

    Fleming, Michael; Feinbloom, Deborah

    1984-01-01

    Discusses the diagnosis of transsexual in terms of its similarities with adolescence. In considering the extreme example of the transsexual, normal adolescent development emerges as more purposive and integrative in the establishment of gender identity. (JAC)

  6. HYPOTHESIS TESTING WITH THE SIMILARITY INDEX

    Science.gov (United States)

    Mulltilocus DNA fingerprinting methods have been used extensively to address genetic issues in wildlife populations. Hypotheses concerning population subdivision and differing levels of diversity can be addressed through the use of the similarity index (S), a band-sharing coeffic...

  7. Bilateral Trade Flows and Income Distribution Similarity.

    Science.gov (United States)

    Martínez-Zarzoso, Inmaculada; Vollmer, Sebastian

    2016-01-01

    Current models of bilateral trade neglect the effects of income distribution. This paper addresses the issue by accounting for non-homothetic consumer preferences and hence investigating the role of income distribution in the context of the gravity model of trade. A theoretically justified gravity model is estimated for disaggregated trade data (Dollar volume is used as dependent variable) using a sample of 104 exporters and 108 importers for 1980-2003 to achieve two main goals. We define and calculate new measures of income distribution similarity and empirically confirm that greater similarity of income distribution between countries implies more trade. Using distribution-based measures as a proxy for demand similarities in gravity models, we find consistent and robust support for the hypothesis that countries with more similar income-distributions trade more with each other. The hypothesis is also confirmed at disaggregated level for differentiated product categories.

  8. Bilateral Trade Flows and Income Distribution Similarity.

    Directory of Open Access Journals (Sweden)

    Inmaculada Martínez-Zarzoso

    Full Text Available Current models of bilateral trade neglect the effects of income distribution. This paper addresses the issue by accounting for non-homothetic consumer preferences and hence investigating the role of income distribution in the context of the gravity model of trade. A theoretically justified gravity model is estimated for disaggregated trade data (Dollar volume is used as dependent variable using a sample of 104 exporters and 108 importers for 1980-2003 to achieve two main goals. We define and calculate new measures of income distribution similarity and empirically confirm that greater similarity of income distribution between countries implies more trade. Using distribution-based measures as a proxy for demand similarities in gravity models, we find consistent and robust support for the hypothesis that countries with more similar income-distributions trade more with each other. The hypothesis is also confirmed at disaggregated level for differentiated product categories.

  9. On self-similarity of crack layer

    Science.gov (United States)

    Botsis, J.; Kunin, B.

    1987-01-01

    The crack layer (CL) theory of Chudnovsky (1986), based on principles of thermodynamics of irreversible processes, employs a crucial hypothesis of self-similarity. The self-similarity hypothesis states that the value of the damage density at a point x of the active zone at a time t coincides with that at the corresponding point in the initial (t = 0) configuration of the active zone, the correspondence being given by a time-dependent affine transformation of the space variables. In this paper, the implications of the self-similarity hypothesis for qusi-static CL propagation is investigated using polystyrene as a model material and examining the evolution of damage distribution along the trailing edge which is approximated by a straight segment perpendicular to the crack path. The results support the self-similarity hypothesis adopted by the CL theory.

  10. Are calanco landforms similar to river basins?

    Science.gov (United States)

    Caraballo-Arias, N A; Ferro, V

    2017-12-15

    In the past badlands have been often considered as ideal field laboratories for studying landscape evolution because of their geometrical similarity to larger fluvial systems. For a given hydrological process, no scientific proof exists that badlands can be considered a model of river basin prototypes. In this paper the measurements carried out on 45 Sicilian calanchi, a type of badlands that appears as a small-scale hydrographic unit, are used to establish their morphological similarity with river systems whose data are available in the literature. At first the geomorphological similarity is studied by identifying the dimensionless groups, which can assume the same value or a scaled one in a fixed ratio, representing drainage basin shape, stream network and relief properties. Then, for each property, the dimensionless groups are calculated for the investigated calanchi and the river basins and their corresponding scale ratio is evaluated. The applicability of Hack's, Horton's and Melton's laws for establishing similarity criteria is also tested. The developed analysis allows to conclude that a quantitative morphological similarity between calanco landforms and river basins can be established using commonly applied dimensionless groups. In particular, the analysis showed that i) calanchi and river basins have a geometrically similar shape respect to the parameters Rf and Re with a scale factor close to 1, ii) calanchi and river basins are similar respect to the bifurcation and length ratios (λ=1), iii) for the investigated calanchi the Melton number assumes values less than that (0.694) corresponding to the river case and a scale ratio ranging from 0.52 and 0.78 can be used, iv) calanchi and river basins have similar mean relief ratio values (λ=1.13) and v) calanchi present active geomorphic processes and therefore fall in a more juvenile stage with respect to river basins. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Similarity search processing. Paralelization and indexing technologies.

    Directory of Open Access Journals (Sweden)

    Eder Dos Santos

    2015-08-01

    The next Scientific-Technical Report addresses the similarity search and the implementation of metric structures on parallel environments. It also presents the state of the art related to similarity search on metric structures and parallelism technologies. Comparative analysis are also proposed, seeking to identify the behavior of a set of metric spaces and metric structures over processing platforms multicore-based and GPU-based.

  12. RFCM Techniques Chamber Facility

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides the capability to develop radio-frequency countermeasure (RFCM) techniques in a controlled environment from 2.0 to 40.0 GHz. The configuration of...

  13. A similarity-based data warehousing environment for medical images.

    Science.gov (United States)

    Teixeira, Jefferson William; Annibal, Luana Peixoto; Felipe, Joaquim Cezar; Ciferri, Ricardo Rodrigues; Ciferri, Cristina Dutra de Aguiar

    2015-11-01

    A core issue of the decision-making process in the medical field is to support the execution of analytical (OLAP) similarity queries over images in data warehousing environments. In this paper, we focus on this issue. We propose imageDWE, a non-conventional data warehousing environment that enables the storage of intrinsic features taken from medical images in a data warehouse and supports OLAP similarity queries over them. To comply with this goal, we introduce the concept of perceptual layer, which is an abstraction used to represent an image dataset according to a given feature descriptor in order to enable similarity search. Based on this concept, we propose the imageDW, an extended data warehouse with dimension tables specifically designed to support one or more perceptual layers. We also detail how to build an imageDW and how to load image data into it. Furthermore, we show how to process OLAP similarity queries composed of a conventional predicate and a similarity search predicate that encompasses the specification of one or more perceptual layers. Moreover, we introduce an index technique to improve the OLAP query processing over images. We carried out performance tests over a data warehouse environment that consolidated medical images from exams of several modalities. The results demonstrated the feasibility and efficiency of our proposed imageDWE to manage images and to process OLAP similarity queries. The results also demonstrated that the use of the proposed index technique guaranteed a great improvement in query processing. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Techniques de combustion Combustin Techniques

    Directory of Open Access Journals (Sweden)

    Perthuis E.

    2006-11-01

    Full Text Available L'efficacité d'un processus de chauffage par flamme est étroitement liée à la maîtrise des techniques de combustion. Le brûleur, organe essentiel de l'équipement de chauffe, doit d'une part assurer une combustion complète pour utiliser au mieux l'énergie potentielle du combustible et, d'autre part, provoquer dans le foyer les conditions aérodynamiques les plus propices oux transferts de chaleur. En s'appuyant sur les études expérimentales effectuées à la Fondation de Recherches Internationales sur les Flammes (FRIF, au Groupe d'Étude des Flammes de Gaz Naturel (GEFGN et à l'Institut Français du Pétrole (IFP et sur des réalisations industrielles, on présente les propriétés essentielles des flammes de diffusion aux combustibles liquides et gazeux obtenues avec ou sans mise en rotation des fluides, et leurs répercussions sur les transferts thermiques. La recherche des températures de combustion élevées conduit à envisager la marche à excès d'air réduit, le réchauffage de l'air ou son enrichissement à l'oxygène. Par quelques exemples, on évoque l'influence de ces paramètres d'exploitation sur l'économie possible en combustible. The efficiency of a flame heating process is closely linked ta the mastery of, combustion techniques. The burner, an essential element in any heating equipment, must provide complete combustion sa as to make optimum use of the potential energy in the fuel while, at the same time, creating the most suitable conditions for heat transfers in the combustion chamber. On the basis of experimental research performed by FRIF, GEFGN and IFP and of industrial achievements, this article describesthe essential properties of diffusion flames fed by liquid and gaseous fuels and produced with or without fluid swirling, and the effects of such flames on heat transfers. The search for high combustion temperatures means that consideration must be given to operating with reduced excess air, heating the air or

  15. The Gestalt Principle of Similarity Benefits Visual Working Memory

    Science.gov (United States)

    Peterson, Dwight J.; Berryhill, Marian E.

    2013-01-01

    Visual working memory (VWM) is essential for many cognitive processes yet it is notably limited in capacity. Visual perception processing is facilitated by Gestalt principles of grouping, such as connectedness, similarity, and proximity. This introduces the question: do these perceptual benefits extend to VWM? If so, can this be an approach to enhance VWM function by optimizing the processing of information? Previous findings demonstrate that several Gestalt principles (connectedness, common region, and spatial proximity) do facilitate VWM performance in change detection tasks (Woodman, Vecera, & Luck, 2003; Xu, 2002a, 2006; Xu & Chun, 2007; Jiang, Olson & Chun, 2000). One prevalent Gestalt principle, similarity, has not been examined with regard to facilitating VWM. Here, we investigated whether grouping by similarity benefits VWM. Experiment 1 established the basic finding that VWM performance could benefit from grouping. Experiment 2 replicated and extended this finding by showing that similarity was only effective when the similar stimuli were proximal. In short, the VWM performance benefit derived from similarity was constrained by spatial proximity such that similar items need to be near each other. Thus, the Gestalt principle of similarity benefits visual perception, but it can provide benefits to VWM as well. PMID:23702981

  16. The Gestalt principle of similarity benefits visual working memory.

    Science.gov (United States)

    Peterson, Dwight J; Berryhill, Marian E

    2013-12-01

    Visual working memory (VWM) is essential for many cognitive processes, yet it is notably limited in capacity. Visual perception processing is facilitated by Gestalt principles of grouping, such as connectedness, similarity, and proximity. This introduces the question, do these perceptual benefits extend to VWM? If so, can this be an approach to enhance VWM function by optimizing the processing of information? Previous findings have demonstrated that several Gestalt principles (connectedness, common region, and spatial proximity) do facilitate VWM performance in change detection tasks (Jiang, Olson, & Chun, 2000; Woodman, Vecera, & Luck, 2003; Xu, 2002, 2006; Xu & Chun, 2007). However, one prevalent Gestalt principle, similarity, has not been examined with regard to facilitating VWM. Here, we investigated whether grouping by similarity benefits VWM. Experiment 1 established the basic finding that VWM performance could benefit from grouping. Experiment 2 replicated and extended this finding by showing that similarity was only effective when the similar stimuli were proximal. In short, the VWM performance benefit derived from similarity was constrained by spatial proximity, such that similar items need to be near each other. Thus, the Gestalt principle of similarity benefits visual perception, but it can provide benefits to VWM as well.

  17. DTreeSim: A new approach to compute decision tree similarity using re-mining

    OpenAIRE

    BAKIRLI, GÖZDE; BİRANT, DERYA

    2017-01-01

    A number of recent studies have used a decision tree approach as a data mining technique; some of them needed to evaluate the similarity of decision trees to compare the knowledge reflected in different trees or datasets. There have been multiple perspectives and multiple calculation techniques to measure the similarity of two decision trees, such as using a simple formula or an entropy measure. The main objective of this study is to compute the similarity of decision trees using ...

  18. Identifying mechanistic similarities in drug responses

    KAUST Repository

    Zhao, C.

    2012-05-15

    Motivation: In early drug development, it would be beneficial to be able to identify those dynamic patterns of gene response that indicate that drugs targeting a particular gene will be likely or not to elicit the desired response. One approach would be to quantitate the degree of similarity between the responses that cells show when exposed to drugs, so that consistencies in the regulation of cellular response processes that produce success or failure can be more readily identified.Results: We track drug response using fluorescent proteins as transcription activity reporters. Our basic assumption is that drugs inducing very similar alteration in transcriptional regulation will produce similar temporal trajectories on many of the reporter proteins and hence be identified as having similarities in their mechanisms of action (MOA). The main body of this work is devoted to characterizing similarity in temporal trajectories/signals. To do so, we must first identify the key points that determine mechanistic similarity between two drug responses. Directly comparing points on the two signals is unrealistic, as it cannot handle delays and speed variations on the time axis. Hence, to capture the similarities between reporter responses, we develop an alignment algorithm that is robust to noise, time delays and is able to find all the contiguous parts of signals centered about a core alignment (reflecting a core mechanism in drug response). Applying the proposed algorithm to a range of real drug experiments shows that the result agrees well with the prior drug MOA knowledge. © The Author 2012. Published by Oxford University Press. All rights reserved.

  19. Emerging optical nanoscopy techniques

    Science.gov (United States)

    Montgomery, Paul C; Leong-Hoi, Audrey

    2015-01-01

    To face the challenges of modern health care, new imaging techniques with subcellular resolution or detection over wide fields are required. Far field optical nanoscopy presents many new solutions, providing high resolution or detection at high speed. We present a new classification scheme to help appreciate the growing number of optical nanoscopy techniques. We underline an important distinction between superresolution techniques that provide improved resolving power and nanodetection techniques for characterizing unresolved nanostructures. Some of the emerging techniques within these two categories are highlighted with applications in biophysics and medicine. Recent techniques employing wider angle imaging by digital holography and scattering lens microscopy allow superresolution to be achieved for subcellular and even in vivo, imaging without labeling. Nanodetection techniques are divided into four subcategories using contrast, phase, deconvolution, and nanomarkers. Contrast enhancement is illustrated by means of a polarized light-based technique and with strobed phase-contrast microscopy to reveal nanostructures. Very high sensitivity phase measurement using interference microscopy is shown to provide nanometric surface roughness measurement or to reveal internal nanometric structures. Finally, the use of nanomarkers is illustrated with stochastic fluorescence microscopy for mapping intracellular structures. We also present some of the future perspectives of optical nanoscopy. PMID:26491270

  20. Emerging optical nanoscopy techniques

    Directory of Open Access Journals (Sweden)

    Montgomery PC

    2015-09-01

    Full Text Available Paul C Montgomery, Audrey Leong-Hoi Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (ICube, Unistra-CNRS, Strasbourg, France Abstract: To face the challenges of modern health care, new imaging techniques with subcellular resolution or detection over wide fields are required. Far field optical nanoscopy presents many new solutions, providing high resolution or detection at high speed. We present a new classification scheme to help appreciate the growing number of optical nanoscopy techniques. We underline an important distinction between superresolution techniques that provide improved resolving power and nanodetection techniques for characterizing unresolved nanostructures. Some of the emerging techniques within these two categories are highlighted with applications in biophysics and medicine. Recent techniques employing wider angle imaging by digital holography and scattering lens microscopy allow superresolution to be achieved for subcellular and even in vivo, imaging without labeling. Nanodetection techniques are divided into four subcategories using contrast, phase, deconvolution, and nanomarkers. Contrast enhancement is illustrated by means of a polarized light-based technique and with strobed phase-contrast microscopy to reveal nanostructures. Very high sensitivity phase measurement using interference microscopy is shown to provide nanometric surface roughness measurement or to reveal internal nanometric structures. Finally, the use of nanomarkers is illustrated with stochastic fluorescence microscopy for mapping intracellular structures. We also present some of the future perspectives of optical nanoscopy. Keywords: microscopy, imaging, superresolution, nanodetection, biophysics, medical imaging

  1. Measure of Node Similarity in Multilayer Networks

    DEFF Research Database (Denmark)

    Møllgaard, Anders; Zettler, Ingo; Dammeyer, Jesper

    2016-01-01

    The weight of links in a network is often related to the similarity of thenodes. Here, we introduce a simple tunable measure for analysing the similarityof nodes across different link weights. In particular, we use the measure toanalyze homophily in a group of 659 freshman students at a large...... university.Our analysis is based on data obtained using smartphones equipped with customdata collection software, complemented by questionnaire-based data. The networkof social contacts is represented as a weighted multilayer network constructedfrom different channels of telecommunication as well as data...... might bepresent in one layer of the multilayer network and simultaneously be absent inthe other layers. For a variable such as gender, our measure reveals atransition from similarity between nodes connected with links of relatively lowweight to dis-similarity for the nodes connected by the strongest...

  2. Fast similarity search for learned metrics.

    Science.gov (United States)

    Kulis, Brian; Jain, Prateek; Grauman, Kristen

    2009-12-01

    We introduce a method that enables scalable similarity search for learned metrics. Given pairwise similarity and dissimilarity constraints between some examples, we learn a Mahalanobis distance function that captures the examples' underlying relationships well. To allow sublinear time similarity search under the learned metric, we show how to encode the learned metric parameterization into randomized locality-sensitive hash functions. We further formulate an indirect solution that enables metric learning and hashing for vector spaces whose high dimensionality makes it infeasible to learn an explicit transformation over the feature dimensions. We demonstrate the approach applied to a variety of image data sets, as well as a systems data set. The learned metrics improve accuracy relative to commonly used metric baselines, while our hashing construction enables efficient indexing with learned distances and very large databases.

  3. Structural similarity and category-specificity

    DEFF Research Database (Denmark)

    Gerlach, Christian; Law, Ian; Paulson, Olaf B

    2004-01-01

    It has been suggested that category-specific recognition disorders for natural objects may reflect that natural objects are more structurally (visually) similar than artefacts and therefore more difficult to recognize following brain damage. On this account one might expect a positive relationship...... between blood flow and structural similarity in areas involved in visual object recognition. Contrary to this expectation we report a negative relationship in that identification of articles of clothing cause more extensive activation than identification of vegetables/fruit and animals even though items...... from the categories of animals and vegetables/fruit are rated as more structurally similar than items from the category of articles of clothing. Given that this pattern cannot be explained in terms of a tradeoff between activation and accuracy, we interpret these findings within a model where...

  4. Similar psychological distance reduces temporal discounting.

    Science.gov (United States)

    Kim, Hyunji; Schnall, Simone; White, Mathew P

    2013-08-01

    People often prefer inferior options in the present even when options in the future are more lucrative. Five studies investigated whether decision making could be improved by manipulating construal level and psychological distance. In Studies 1a, 1b, and 2, temporal discounting was reduced when future rewards (trips to Paris) were construed at a relatively concrete level, thus inducing a similar level of construal to present rewards. By contrast, Studies 3 and 4 reduced temporal discounting by making present financial rewards more psychologically distant via a social proximity manipulation, and thus linked to a similar high level of construal as future rewards. These results suggest that people prefer the more lucrative option when comparing two intertemporal choices that are construed on a similar level instead of on a different level. Thus, changes in construal level and mental representations can be used to promote more desirable choices in economic decision making.

  5. Unveiling Music Structure Via PLSA Similarity Fusion

    DEFF Research Database (Denmark)

    Arenas-García, Jerónimo; Meng, Anders; Petersen, Kaare Brandt

    2007-01-01

    observed similarities can be satisfactorily explained using the latent semantics. Additionally, this approach significantly simplifies the song retrieval phase, leading to a more practical system implementation. The suitability of the PLSA model for representing music structure is studied in a simplified......Nowadays there is an increasing interest in developing methods for building music recommendation systems. In order to get a satisfactory performance from such a system, one needs to incorporate as much information about songs similarity as possible; however, how to do so is not obvious...

  6. Cultural similarity and adjustment of expatriate academics

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2009-01-01

    The findings of a number of recent empirical studies of business expatriates, using different samples and methodologies, seem to support the counter-intuitive proposition that cultural similarity may be as difficult to adjust to as cultural dissimilarity. However, it is not obvious...... and non-EU countries. Results showed that although the perceived cultural similarity between host and home country for the two groups of investigated respondents was different, there was neither any difference in their adjustment nor in the time it took for them to become proficient. Implications...

  7. The similarity principle - on using models correctly

    DEFF Research Database (Denmark)

    Landberg, L.; Mortensen, N.G.; Rathmann, O.

    2003-01-01

    This paper will present some guiding principles on the most accurate use of the WAsP program in particular, but the principle can be applied to the use of any linear model which predicts some quantity at one location based on another. We have felt a need to lay out these principles out explicitly......, due to the many, many users and the uses (and misuses) of the WAsP program. Put simply, the similarity principle states that one should chose a predictor site which – in as many ways as possible – is similar to the predicted site....

  8. Related herbivore species show similar temporal dynamics.

    Science.gov (United States)

    Blanchet, F G; Roslin, T; Kimura, M T; Huotari, T; Kaartinen, R; Gripenberg, S; Tack, A J M

    2018-02-08

    1.Within natural communities, different taxa display different dynamics in time. Why this is the case we do not fully know. This thwarts our ability to predict changes in community structure, which is important for both the conservation of rare species in natural communities and for the prediction of pest outbreaks in agriculture. 2.Species sharing phylogeny, natural enemies and/or life history traits have been hypothesized to share similar temporal dynamics. We operationalized these concepts into testing whether feeding guild, voltinism, similarity in parasitoid community, and/or phylogenetic relatedness explained similarities in temporal dynamics among herbivorous community members. 3.Focusing on two similar data sets from different geographical regions (Finland and Japan), we used asymmetric eigenvector maps as temporal variables to characterize species- and community-level dynamics of specialist insect herbivores on oak (Quercus). We then assessed whether feeding guild, voltinism, similarity in parasitoid community, and/or phylogenetic relatedness explained similarities in temporal dynamics among taxa. 4.Species-specific temporal dynamics varied widely, ranging from directional decline or increase to more complex patterns. Phylogeny was a clear predictor of similarity in temporal dynamics at the Finnish site, whereas for the Japanese site, the data were uninformative regarding a phylogenetic imprint. Voltinism, feeding guild and parasitoid overlap explained little variation at either location. Despite the rapid temporal dynamics observed at the level of individual species, these changes did not translate into any consistent temporal changes at the community level in either Finland or Japan. 5.Overall, our findings offer no direct support for the notion that species sharing natural enemies and/or life history traits would be characterised by similar temporal dynamics, but reveal a strong imprint of phylogenetic relatedness. As this phylogenetic signal cannot be

  9. A ligand's view of target similarity

    DEFF Research Database (Denmark)

    Garland, Stephen L; Gloriam, David E

    2011-01-01

    GPCR binding site-directed techniques are rapidly evolving into powerful tools for modern drug discovery. Many of these approaches bridge chemistry and biology, which are inseparable concepts in nature but are often treated as separate worlds in drug discovery and science in general. This review ...

  10. Provider of Services File

    Data.gov (United States)

    U.S. Department of Health & Human Services — The POS file consists of two data files, one for CLIA labs and one for 18 other provider types. The file names are CLIA and OTHER. If downloading the file, note it...

  11. care Providers in Ibadan

    African Journals Online (AJOL)

    Perception et pratique de la prophylaxie du paludisme pendant la grossesse chez les dispensateurs des soins de santé à Ibadan ... 2007; ll[2]:69-78). Key Words: malaria in pregnancy, intermittent preventive treatment, malaria control, health care providers ..... changing practice8; incorporating new strategies into routine ...

  12. What HERA may provide?

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Hannes [DESY, Hamburg (Germany); De Roeck, Albert [CERN, Genf (Switzerland); Bartles, Jochen [Univ. Hamburg (DE). Institut fuer Theoretische Physik II] (and others)

    2008-09-15

    More than 100 people participated in a discussion session at the DIS08 workshop on the topic What HERA may provide. A summary of the discussion with a structured outlook and list of desirable measurements and theory calculations is given. (orig.)

  13. Nuclear markers reveal that inter-lake cichlids' similar morphologies do not reflect similar genealogy.

    Science.gov (United States)

    Kassam, Daud; Seki, Shingo; Horic, Michio; Yamaoka, Kosaku

    2006-08-01

    The apparent inter-lake morphological similarity among East African Great Lakes' cichlid species/genera has left evolutionary biologists asking whether such similarity is due to sharing of common ancestor or mere convergent evolution. In order to answer such question, we first used Geometric Morphometrics, GM, to quantify morphological similarity and then subsequently used Amplified Fragment Length Polymorphism, AFLP, to determine if similar morphologies imply shared ancestry or convergent evolution. GM revealed that not all presumed morphological similar pairs were indeed similar, and the dendrogram generated from AFLP data indicated distinct clusters corresponding to each lake and not inter-lake morphological similar pairs. Such results imply that the morphological similarity is due to convergent evolution and not shared ancestry. The congruency of GM and AFLP generated dendrograms imply that GM is capable of picking up phylogenetic signal, and thus GM can be potential tool in phylogenetic systematics.

  14. Measuring structural similarity in large online networks.

    Science.gov (United States)

    Shi, Yongren; Macy, Michael

    2016-09-01

    Structural similarity based on bipartite graphs can be used to detect meaningful communities, but the networks have been tiny compared to massive online networks. Scalability is important in applications involving tens of millions of individuals with highly skewed degree distributions. Simulation analysis holding underlying similarity constant shows that two widely used measures - Jaccard index and cosine similarity - are biased by the distribution of out-degree in web-scale networks. However, an alternative measure, the Standardized Co-incident Ratio (SCR), is unbiased. We apply SCR to members of Congress, musical artists, and professional sports teams to show how massive co-following on Twitter can be used to map meaningful affiliations among cultural entities, even in the absence of direct connections to one another. Our results show how structural similarity can be used to map cultural alignments and demonstrate the potential usefulness of social media data in the study of culture, politics, and organizations across the social and behavioral sciences. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Great Apes' Capacities to Recognize Relational Similarity

    Science.gov (United States)

    Haun, Daniel B. M.; Call, Josep

    2009-01-01

    Recognizing relational similarity relies on the ability to understand that defining object properties might not lie in the objects individually, but in the relations of the properties of various object to each other. This aptitude is highly relevant for many important human skills such as language, reasoning, categorization and understanding…

  16. Music Retrieval based on Melodic Similarity

    NARCIS (Netherlands)

    Typke, R.

    2007-01-01

    This thesis introduces a method for measuring melodic similarity for notated music such as MIDI files. This music search algorithm views music as sets of notes that are represented as weighted points in the two-dimensional space of time and pitch. Two point sets can be compared by calculating how

  17. Anthropogenic and impact spherules: Morphological similarity and ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 120; Issue 6. Anthropogenic and impact spherules: Morphological similarity and chemical distinction – A case study from India and its implications. Ambalika Niyogi Jayanta K Pati Suresh C Patel Dipak Panda Shiv K Patil. Volume 120 Issue 6 December 2011 pp ...

  18. Normalized Web Distance and Word Similarity

    NARCIS (Netherlands)

    R. Cilibrasi (Rudi); P.M.B. Vitányi (Paul)

    2009-01-01

    htmlabstractThere is a great deal of work in cognitive psychology, linguistics, and computer science, about using word (or phrase) frequencies in context in text corpora to develop measures for word similarity or word association, going back to at least the 1960s. The goal of this chapter is to

  19. Normalized Web Distance and Word Similarity

    NARCIS (Netherlands)

    R. Cilibrasi (Rudi); P.M.B. Vitányi (Paul); N. Indurkhya; F.J. Damerau

    2010-01-01

    htmlabstractThere is a great deal of work in cognitive psychology, linguistics, and computer science, about using word (or phrase) frequencies in context in text corpora to develop measures for word similarity or word association, going back to at least the 1960s. The goal of this chapter is to

  20. Learning by similarity in coordination problems

    Czech Academy of Sciences Publication Activity Database

    Steiner, Jakub; Stewart, C.

    -, č. 324 (2007), s. 1-40 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : similarity * learning * case-based reasoning Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp324.pdf

  1. Cross-kingdom similarities in microbiome functions

    NARCIS (Netherlands)

    Mendes, R.; Raaijmakers, J.M.

    2015-01-01

    Recent advances in medical research have revealed how humans rely on their microbiome for diverse traits and functions. Similarly, microbiomes of other higher organisms play key roles in disease, health, growth and development of their host. Exploring microbiome functions across kingdoms holds

  2. Measurement of Similarity in Academic Contexts

    Directory of Open Access Journals (Sweden)

    Omid Mahian

    2017-06-01

    Full Text Available We propose some reflections, comments and suggestions about the measurement of similar and matched content in scientific papers and documents, and the need to develop appropriate tools and standards for an ethically fair and equitable treatment of authors.

  3. improvement of digital image watermarking techniques based on FPGA implementation

    International Nuclear Information System (INIS)

    EL-Hadedy, M.E

    2006-01-01

    digital watermarking provides the ownership of a piece of digital data by marking the considered data invisibly or visibly. this can be used to protect several types of multimedia objects such as audio, text, image and video. this thesis demonstrates the different types of watermarking techniques such as (discrete cosine transform (DCT) and discrete wavelet transform (DWT) and their characteristics. then, it classifies these techniques declaring their advantages and disadvantages. an improved technique with distinguished features, such as peak signal to noise ratio ( PSNR) and similarity ratio (SR) has been introduced. the modified technique has been compared with the other techniques by measuring heir robustness against differ attacks. finally, field programmable gate arrays (FPGA) based implementation and comparison, for the proposed watermarking technique have been presented and discussed

  4. Extending the Similarity-Attraction Effect : The effects of When-Similarity in mediated communication

    NARCIS (Netherlands)

    Kaptein, M.C.; Castaneda, D.; Fernandez, N.; Nass, C.

    2014-01-01

    The feeling of connectedness experienced in computer-mediated relationships can be explained by the similarity-attraction effect (SAE). Though SAE is well established in psychology, the effects of some types of similarity have not yet been explored. In 2 studies, we demonstrate similarity-attraction

  5. A New Similarity Measure between Intuitionistic Fuzzy Sets and Its Application to Pattern Recognition

    Directory of Open Access Journals (Sweden)

    Yafei Song

    2014-01-01

    Full Text Available As a generation of ordinary fuzzy set, the concept of intuitionistic fuzzy set (IFS, characterized both by a membership degree and by a nonmembership degree, is a more flexible way to cope with the uncertainty. Similarity measures of intuitionistic fuzzy sets are used to indicate the similarity degree between intuitionistic fuzzy sets. Although many similarity measures for intuitionistic fuzzy sets have been proposed in previous studies, some of those cannot satisfy the axioms of similarity or provide counterintuitive cases. In this paper, a new similarity measure and weighted similarity measure between IFSs are proposed. It proves that the proposed similarity measures satisfy the properties of the axiomatic definition for similarity measures. Comparison between the previous similarity measures and the proposed similarity measure indicates that the proposed similarity measure does not provide any counterintuitive cases. Moreover, it is demonstrated that the proposed similarity measure is capable of discriminating difference between patterns.

  6. Achieving Provider Engagement

    Science.gov (United States)

    Greenfield, Geva; Pappas, Yannis; Car, Josip; Majeed, Azeem; Harris, Matthew

    2014-01-01

    The literature on integrated care is limited with respect to practical learning and experience. Although some attention has been paid to organizational processes and structures, not enough is paid to people, relationships, and the importance of these in bringing about integration. Little is known, for example, about provider engagement in the organizational change process, how to obtain and maintain it, and how it is demonstrated in the delivery of integrated care. Based on qualitative data from the evaluation of a large-scale integrated care initiative in London, United Kingdom, we explored the role of provider engagement in effective integration of services. Using thematic analysis, we identified an evolving engagement narrative with three distinct phases: enthusiasm, antipathy, and ambivalence, and argue that health care managers need to be aware of the impact of professional engagement to succeed in advancing the integrated care agenda. PMID:25212855

  7. Providing plastic zone extrusion

    Science.gov (United States)

    Manchiraju, Venkata Kiran; Feng, Zhili; David, Stan A.; Yu, Zhenzhen

    2017-04-11

    Plastic zone extrusion may be provided. First, a compressor may generate frictional heat in stock to place the stock in a plastic zone of the stock. Then, a conveyer may receive the stock in its plastic zone from the compressor and transport the stock in its plastic zone from the compressor. Next, a die may receive the stock in its plastic zone from the conveyer and extrude the stock to form a wire.

  8. Providing x-rays

    International Nuclear Information System (INIS)

    Mallozzi, P.J.; Epstein, H.M.

    1985-01-01

    This invention provides an apparatus for providing x-rays to an object that may be in an ordinary environment such as air at approximately atmospheric pressure. The apparatus comprises: means (typically a laser beam) for directing energy onto a target to produce x-rays of a selected spectrum and intensity at the target; a fluid-tight enclosure around the target; means for maintaining the pressure in the first enclosure substantially below atmospheric pressure; a fluid-tight second enclosure adjoining the first enclosure, the common wall portion having an opening large enough to permit x-rays to pass through but small enough to allow the pressure reducing means to evacuate gas from the first enclosure at least as fast as it enters through the opening; the second enclosure filled with a gas that is highly transparent to x-rays; the wall of the second enclosure to which the x-rays travel having a portion that is highly transparent to x-rays (usually a beryllium or plastic foil), so that the object to which the x-rays are to be provided may be located outside the second enclosure and adjacent thereto and thus receive the x-rays substantially unimpeded by air or other intervening matter. The apparatus is particularly suited to obtaining EXAFS (extended x-ray fine structure spectroscopy) data on a material

  9. PROVIDING WOMEN, KEPT MEN

    Science.gov (United States)

    Mojola, Sanyu A

    2014-01-01

    This paper draws on ethnographic and interview based fieldwork to explore accounts of intimate relationships between widowed women and poor young men that emerged in the wake of economic crisis and a devastating HIV epidemic among the Luo ethnic group in Western Kenya. I show how the cooptation of widow inheritance practices in the wake of an overwhelming number of widows as well as economic crisis resulted in widows becoming providing women and poor young men becoming kept men. I illustrate how widows in this setting, by performing a set of practices central to what it meant to be a man in this society – pursuing and providing for their partners - were effectively doing masculinity. I will also show how young men, rather than being feminized by being kept, deployed other sets of practices to prove their masculinity and live in a manner congruent with cultural ideals. I argue that ultimately, women’s practice of masculinity in large part seemed to serve patriarchal ends. It not only facilitated the fulfillment of patriarchal expectations of femininity – to being inherited – but also served, in the end, to provide a material base for young men’s deployment of legitimizing and culturally valued sets of masculine practice. PMID:25489121

  10. Contextual Factors for Finding Similar Experts

    DEFF Research Database (Denmark)

    Hofmann, Katja; Balog, Krisztian; Bogers, Toine

    2010-01-01

    Expertise-seeking research studies how people search for expertise and choose whom to contact in the context of a specific task. An important outcome are models that identify factors that influence expert finding. Expertise retrieval addresses the same problem, expert finding, but from a system......-centered perspective. The main focus has been on developing content-based algorithms similar to document search. These algorithms identify matching experts primarily on the basis of the textual content of documents with which experts are associated. Other factors, such as the ones identified by expertise......-seeking models, are rarely taken into account. In this article, we extend content-based expert-finding approaches with contextual factors that have been found to influence human expert finding. We focus on a task of science communicators in a knowledge-intensive environment, the task of finding similar experts...

  11. Similarity Arguments in the Genetic Modification Debate

    DEFF Research Database (Denmark)

    Christiansen, Andreas

    2017-01-01

    In the ethical debate on genetic modification (GM), it is common to encounter the claim that some anti-GM argument would also apply an established, ethically accepted technology, and that the anti-GM argument is therefore unsuccessful. The paper discusses whether this argumentative strategy...... transferability of reasons from one case to another; and (iii) it runs the risk of equivocations, especially in cases where the anti-genetic-modification argument relies on gradable features. The paper then shows how these issues play out in three specific Similarity Arguments that can be found in the literature....... Finally, the paper discusses what conclusions we can draw from the fact that genetic modification and established technologies are similar for the ethical status of genetic modification....

  12. Relations between premise similarity and inductive strength.

    Science.gov (United States)

    Heit, Evan; Feeney, Aidan

    2005-04-01

    According to the diversity principle, diverse evidence is strong evidence. There has been considerable evidence that people respect this principle in inductive reasoning. However, exceptions may be particularly informative. Medin, Coley, Storms, and Hayes (2003) introduced a relevance theory of inductive reasoning and used this theory to predict exceptions, including the nondiversity-by-property-reinforcement effect. A new experiment in which this phenomenon was investigated is reported here. Subjects made inductive strength judgments and similarity judgments for stimuli from Medin et al. (2003). The inductive strength judgments showed the same pattern as that in Medin et al. (2003); however, the similarity judgments suggested that the pattern should be interpreted as a diversity effect, rather than as a nondiversity effect. It is concluded that the evidence regarding the predicted nondiversity-by-property-reinforcement effect does not give distinctive support for relevance theory, although this theory does address other results.

  13. Multidimensional Scaling Visualization Using Parametric Similarity Indices

    OpenAIRE

    Machado, J. Tenreiro; Lopes, António; Galhano, Alexandra

    2015-01-01

    In this paper, we apply multidimensional scaling (MDS) and parametric similarity indices (PSI) in the analysis of complex systems (CS). Each CS is viewed as a dynamical system, exhibiting an output time-series to be interpreted as a manifestation of its behavior. We start by adopting a sliding window to sample the original data into several consecutive time periods. Second, we define a given PSI for tracking pieces of data. We then compare the windows for different values of the parameter, an...

  14. Quasi-Similarity Model of Synthetic Jets

    Czech Academy of Sciences Publication Activity Database

    Tesař, Václav; Kordík, Jozef

    2009-01-01

    Roč. 149, č. 2 (2009), s. 255-265 ISSN 0924-4247 R&D Projects: GA AV ČR IAA200760705; GA ČR GA101/07/1499 Institutional research plan: CEZ:AV0Z20760514 Keywords : jets * synthetic jets * similarity solution Subject RIV: BK - Fluid Dynamics Impact factor: 1.674, year: 2009 http://www.sciencedirect.com

  15. Similarity solutions for phase-change problems

    Science.gov (United States)

    Canright, D.; Davis, S. H.

    1989-01-01

    A modification of Ivantsov's (1947) similarity solutions is proposed which can describe phase-change processes which are limited by diffusion. The method has application to systems that have n-components and possess cross-diffusion and Soret and Dufour effects, along with convection driven by density discontinuities at the two-phase interface. Local thermal equilibrium is assumed at the interface. It is shown that analytic solutions are possible when the material properties are constant.

  16. Stochastic self-similar and fractal universe

    International Nuclear Information System (INIS)

    Iovane, G.; Laserra, E.; Tortoriello, F.S.

    2004-01-01

    The structures formation of the Universe appears as if it were a classically self-similar random process at all astrophysical scales. An agreement is demonstrated for the present hypotheses of segregation with a size of astrophysical structures by using a comparison between quantum quantities and astrophysical ones. We present the observed segregated Universe as the result of a fundamental self-similar law, which generalizes the Compton wavelength relation. It appears that the Universe has a memory of its quantum origin as suggested by R. Penrose with respect to quasi-crystal. A more accurate analysis shows that the present theory can be extended from the astrophysical to the nuclear scale by using generalized (stochastically) self-similar random process. This transition is connected to the relevant presence of the electromagnetic and nuclear interactions inside the matter. In this sense, the presented rule is correct from a subatomic scale to an astrophysical one. We discuss the near full agreement at organic cell scale and human scale too. Consequently the Universe, with its structures at all scales (atomic nucleus, organic cell, human, planet, solar system, galaxy, clusters of galaxy, super clusters of galaxy), could have a fundamental quantum reason. In conclusion, we analyze the spatial dimensions of the objects in the Universe as well as space-time dimensions. The result is that it seems we live in an El Naschie's E-infinity Cantorian space-time; so we must seriously start considering fractal geometry as the geometry of nature, a type of arena where the laws of physics appear at each scale in a self-similar way as advocated long ago by the Swedish school of astrophysics

  17. Strain Elastography of Breast and Prostata Cancer: Similarities and Differences.

    Science.gov (United States)

    Daniaux, M; Auer, T; De Zordo, T; Junker, D; Santner, W; Hubalek, M; Jaschke, W; Aigner, F

    2016-03-01

    Typically both breast and prostate cancer present as tissue with decreased elasticity. Palpation is the oldest technique of tumor detection in both organs and is based on this principle. Thus an operator can grade a palpable mass as suspicious for cancer. Strain elastography as modern ultrasound technique allows the visualization of tissue elasticity in a color coded elastogram and can be understood as technical finger. The following article shows similarities and differences of ultrasound strain elastography in the diagnosis of breast and prostate cancer. • In prostata cancer elastography, in breast cancer B-mode is the primary sonographic search modality. • The diagnostic value of the search modalities change with increasing age.• A cut-off value for a strain ratio is hard to obtain in the elastography of the prostata, because there is no stabile reference tissue in the prostata. © Georg Thieme Verlag KG Stuttgart · New York.

  18. The Unknown Computer Viruses Detection Based on Similarity

    Science.gov (United States)

    Liu, Zhongda; Nakaya, Naoshi; Koui, Yuuji

    New computer viruses are continually being generated and they cause damage all over the world. In general, current anti-virus software detects viruses by matching a pattern based on the signature; thus, unknown viruses without any signature cannot be detected. Although there are some static analysis technologies that do not depend on signatures, virus writers often use code obfuscation techniques, which make it difficult to execute a code analysis. As is generally known, unknown viruses and known viruses share a common feature. In this paper we propose a new static analysis technology that can circumvent code obfuscation to extract the common feature and detect unknown viruses based on similarity. The results of evaluation experiments demonstrated that this technique is able to detect unknown viruses without false positives.

  19. Semantic Annotation of Unstructured Documents Using Concepts Similarity

    Directory of Open Access Journals (Sweden)

    Fernando Pech

    2017-01-01

    Full Text Available There is a large amount of information in the form of unstructured documents which pose challenges in the information storage, search, and retrieval. This situation has given rise to several information search approaches. Some proposals take into account the contextual meaning of the terms specified in the query. Semantic annotation technique can help to retrieve and extract information in unstructured documents. We propose a semantic annotation strategy for unstructured documents as part of a semantic search engine. In this proposal, ontologies are used to determine the context of the entities specified in the query. Our strategy for extracting the context is focused on concepts similarity. Each relevant term of the document is associated with an instance in the ontology. The similarity between each of the explicit relationships is measured through the combination of two types of associations: the association between each pair of concepts and the calculation of the weight of the relationships.

  20. Protein-protein interaction based on pairwise similarity

    Directory of Open Access Journals (Sweden)

    Zaki Nazar

    2009-05-01

    Full Text Available Abstract Background Protein-protein interaction (PPI is essential to most biological processes. Abnormal interactions may have implications in a number of neurological syndromes. Given that the association and dissociation of protein molecules is crucial, computational tools capable of effectively identifying PPI are desirable. In this paper, we propose a simple yet effective method to detect PPI based on pairwise similarity and using only the primary structure of the protein. The PPI based on Pairwise Similarity (PPI-PS method consists of a representation of each protein sequence by a vector of pairwise similarities against large subsequences of amino acids created by a shifting window which passes over concatenated protein training sequences. Each coordinate of this vector is typically the E-value of the Smith-Waterman score. These vectors are then used to compute the kernel matrix which will be exploited in conjunction with support vector machines. Results To assess the ability of the proposed method to recognize the difference between "interacted" and "non-interacted" proteins pairs, we applied it on different datasets from the available yeast saccharomyces cerevisiae protein interaction. The proposed method achieved reasonable improvement over the existing state-of-the-art methods for PPI prediction. Conclusion Pairwise similarity score provides a relevant measure of similarity between protein sequences. This similarity incorporates biological knowledge about proteins and it is extremely powerful when combined with support vector machine to predict PPI.

  1. The Application of Similar Image Retrieval in Electronic Commerce

    Directory of Open Access Journals (Sweden)

    YuPing Hu

    2014-01-01

    Full Text Available Traditional online shopping platform (OSP, which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers’ experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system.

  2. The application of similar image retrieval in electronic commerce.

    Science.gov (United States)

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system.

  3. The Application of Similar Image Retrieval in Electronic Commerce

    Science.gov (United States)

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system. PMID:24883411

  4. Energy providers: customer expectations

    International Nuclear Information System (INIS)

    Pridham, N.F.

    1997-01-01

    The deregulation of the gas and electric power industries, and how it will impact on customer service and pricing rates was discussed. This paper described the present situation, reviewed core competencies, and outlined future expectations. The bottom line is that major energy consumers are very conscious of energy costs and go to great lengths to keep them under control. At the same time, solutions proposed to reduce energy costs must benefit all classes of consumers, be they industrial, commercial, institutional or residential. Deregulation and competition at an accelerated pace is the most likely answer. This may be forced by external forces such as foreign energy providers who are eager to enter the Canadian energy market. It is also likely that the competition and convergence between gas and electricity is just the beginning, and may well be overshadowed by other deregulated industries as they determine their core competencies

  5. Efficient estimation for high similarities using odd sketches

    DEFF Research Database (Denmark)

    Mitzenmacher, Michael; Pagh, Rasmus; Pham, Ninh Dang

    2014-01-01

    . This means that Odd Sketches provide a highly space-efficient estimator for sets of high similarity, which is relevant in applications such as web duplicate detection, collaborative filtering, and association rule learning. The method extends to weighted Jaccard similarity, relevant e.g. for TF-IDF vector...... comparison. We present a theoretical analysis of the quality of estimation to guarantee the reliability of Odd Sketch-based estimators. Our experiments confirm this efficiency, and demonstrate the efficiency of Odd Sketches in comparison with $b$-bit minwise hashing schemes on association rule learning...

  6. A new technique for solving puzzles.

    Science.gov (United States)

    Makridis, Michael; Papamarkos, Nikos

    2010-06-01

    This paper proposes a new technique for solving jigsaw puzzles. The novelty of the proposed technique is that it provides an automatic jigsaw puzzle solution without any initial restriction about the shape of pieces, the number of neighbor pieces, etc. The proposed technique uses both curve- and color-matching similarity features. A recurrent procedure is applied, which compares and merges puzzle pieces in pairs, until the original puzzle image is reformed. Geometrical and color features are extracted on the characteristic points (CPs) of the puzzle pieces. CPs, which can be considered as high curvature points, are detected by a rotationally invariant corner detection algorithm. The features which are associated with color are provided by applying a color reduction technique using the Kohonen self-organized feature map. Finally, a postprocessing stage checks and corrects the relative position between puzzle pieces to improve the quality of the resulting image. Experimental results prove the efficiency of the proposed technique, which can be further extended to deal with even more complex jigsaw puzzle problems.

  7. Applying contemporary statistical techniques

    CERN Document Server

    Wilcox, Rand R

    2003-01-01

    Applying Contemporary Statistical Techniques explains why traditional statistical methods are often inadequate or outdated when applied to modern problems. Wilcox demonstrates how new and more powerful techniques address these problems far more effectively, making these modern robust methods understandable, practical, and easily accessible.* Assumes no previous training in statistics * Explains how and why modern statistical methods provide more accurate results than conventional methods* Covers the latest developments on multiple comparisons * Includes recent advanc

  8. Optimization techniques in statistics

    CERN Document Server

    Rustagi, Jagdish S

    1994-01-01

    Statistics help guide us to optimal decisions under uncertainty. A large variety of statistical problems are essentially solutions to optimization problems. The mathematical techniques of optimization are fundamentalto statistical theory and practice. In this book, Jagdish Rustagi provides full-spectrum coverage of these methods, ranging from classical optimization and Lagrange multipliers, to numerical techniques using gradients or direct search, to linear, nonlinear, and dynamic programming using the Kuhn-Tucker conditions or the Pontryagin maximal principle. Variational methods and optimiza

  9. Assisted reproductive techniques.

    Science.gov (United States)

    Huang, Jack Yu Jen; Rosenwaks, Zev

    2014-01-01

    Assisted reproductive technologies (ART) encompass fertility treatments, which involve manipulations of both oocyte and sperm in vitro. This chapter provides a brief overview of ART, including indications for treatment, ovarian reserve testing, selection of controlled ovarian hyperstimulation (COH) protocols, laboratory techniques of ART including in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI), embryo transfer techniques, and luteal phase support. This chapter also discusses potential complications of ART, namely ovarian hyperstimulation syndrome (OHSS) and multiple gestations, and the perinatal outcomes of ART.

  10. Computer techniques for electromagnetics

    CERN Document Server

    Mittra, R

    1973-01-01

    Computer Techniques for Electromagnetics discusses the ways in which computer techniques solve practical problems in electromagnetics. It discusses the impact of the emergence of high-speed computers in the study of electromagnetics. This text provides a brief background on the approaches used by mathematical analysts in solving integral equations. It also demonstrates how to use computer techniques in computing current distribution, radar scattering, and waveguide discontinuities, and inverse scattering. This book will be useful for students looking for a comprehensive text on computer techni

  11. Spectrometric techniques 2

    CERN Document Server

    Vanasse, George A

    2013-01-01

    Spectrometric Techniques, Volume II provides information pertinent to vacuum ultraviolet techniques to complete the demonstration of the diversity of methods available to the spectroscopist interested in the ultraviolet visible and infrared spectral regions. This book discusses the specific aspects of the technique of Fourier transform spectroscopy.Organized into five chapters, this volume begins with an overview of the large number of systematic effects in the recording of an interferogram. This text then examines the design approach for a Fourier transform spectrometer with focus on optics.

  12. Conditioned real self-similar Markov processes

    OpenAIRE

    Kyprianou, Andreas E.; Rivero, Víctor M.; Satitkanitkul, Weerapat

    2015-01-01

    In recent work, Chaumont et al. [9] showed that is possible to condition a stable process with index ${\\alpha} \\in (1,2)$ to avoid the origin. Specifically, they describe a new Markov process which is the Doob h-transform of a stable process and which arises from a limiting procedure in which the stable process is conditioned to have avoided the origin at later and later times. A stable process is a particular example of a real self-similar Markov process (rssMp) and we develop the idea of su...

  13. Modeling Timbre Similarity of Short Music Clips.

    Science.gov (United States)

    Siedenburg, Kai; Müllensiefen, Daniel

    2017-01-01

    There is evidence from a number of recent studies that most listeners are able to extract information related to song identity, emotion, or genre from music excerpts with durations in the range of tenths of seconds. Because of these very short durations, timbre as a multifaceted auditory attribute appears as a plausible candidate for the type of features that listeners make use of when processing short music excerpts. However, the importance of timbre in listening tasks that involve short excerpts has not yet been demonstrated empirically. Hence, the goal of this study was to develop a method that allows to explore to what degree similarity judgments of short music clips can be modeled with low-level acoustic features related to timbre. We utilized the similarity data from two large samples of participants: Sample I was obtained via an online survey, used 16 clips of 400 ms length, and contained responses of 137,339 participants. Sample II was collected in a lab environment, used 16 clips of 800 ms length, and contained responses from 648 participants. Our model used two sets of audio features which included commonly used timbre descriptors and the well-known Mel-frequency cepstral coefficients as well as their temporal derivates. In order to predict pairwise similarities, the resulting distances between clips in terms of their audio features were used as predictor variables with partial least-squares regression. We found that a sparse selection of three to seven features from both descriptor sets-mainly encoding the coarse shape of the spectrum as well as spectrotemporal variability-best predicted similarities across the two sets of sounds. Notably, the inclusion of non-acoustic predictors of musical genre and record release date allowed much better generalization performance and explained up to 50% of shared variance ( R 2 ) between observations and model predictions. Overall, the results of this study empirically demonstrate that both acoustic features related

  14. What HERA May Provide?

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Hannes; /DESY; De Roeck, Albert; /CERN; Bartels, Jochen; /Hamburg U., Inst. Theor. Phys. II; Behnke, Olaf; Blumlein, Johannes; /DESY; Brodsky, Stanley; /SLAC /Durham U., IPPP; Cooper-Sarkar, Amanda; /Oxford U.; Deak, Michal; /DESY; Devenish, Robin; /Oxford U.; Diehl, Markus; /DESY; Gehrmann, Thomas; /Zurich U.; Grindhammer, Guenter; /Munich, Max Planck Inst.; Gustafson, Gosta; /CERN /Lund U., Dept. Theor. Phys.; Khoze, Valery; /Durham U., IPPP; Knutsson, Albert; /DESY; Klein, Max; /Liverpool U.; Krauss, Frank; /Durham U., IPPP; Kutak, Krzysztof; /DESY; Laenen, Eric; /NIKHEF, Amsterdam; Lonnblad, Leif; /Lund U., Dept. Theor. Phys.; Motyka, Leszek; /Hamburg U., Inst. Theor. Phys. II /Birmingham U. /Southern Methodist U. /DESY /Piemonte Orientale U., Novara /CERN /Paris, LPTHE /Hamburg U. /Penn State U.

    2011-11-10

    More than 100 people participated in a discussion session at the DIS08 workshop on the topic What HERA may provide. A summary of the discussion with a structured outlook and list of desirable measurements and theory calculations is given. The HERA accelerator and the HERA experiments H1, HERMES and ZEUS stopped running in the end of June 2007. This was after 15 years of very successful operation since the first collisions in 1992. A total luminosity of {approx} 500 pb{sup -1} has been accumulated by each of the collider experiments H1 and ZEUS. During the years the increasingly better understood and upgraded detectors and HERA accelerator have contributed significantly to this success. The physics program remains in full swing and plenty of new results were presented at DIS08 which are approaching the anticipated final precision, fulfilling and exceeding the physics plans and the previsions of the upgrade program. Most of the analyses presented at DIS08 were still based on the so called HERA I data sample, i.e. data taken until 2000, before the shutdown for the luminosity upgrade. This sample has an integrated luminosity of {approx} 100 pb{sup -1}, and the four times larger statistics sample from HERA II is still in the process of being analyzed.

  15. Radionuclide techniques

    International Nuclear Information System (INIS)

    Alazraki, N.

    1988-01-01

    During approximately 25 years of experience with bone scanning, broad expansions in the clinical impact of radionuclide imaging on disorders of bones, joints, and soft tissues have occurred. This increased impact had its groundwork laid by advances in radiopharmaceuticals and instruments that are used for bone imaging. The progression from /sup 85/Sr- to /sup 99m/Tc-labeled phosphate and phosphonate compounds, coupled with the advance from crude rectilinear scanning techniques to whole body scintillation imaging with large crystal cameras and sophisticated electronics, has encourage use of radionuclide techniques in the evaluation of muscoloskeletal diseases. Many clinical studies have documented the high degree of sensitivity of the bone scan compared with that of the radiograph in detecting osseous and articular abnormalities

  16. MetMaxStruct: a Tversky-similarity-based strategy for analysing the (substructural similarities of drugs and endogenous metabolites

    Directory of Open Access Journals (Sweden)

    Steve O'Hagan

    2016-08-01

    a numerical similarity much closer to drugs than do even endogenites. Conclusions. Overall, the Tversky similarity metrics provide a more useful range of examples of molecular similarity than does the simpler Tanimoto similarity, and help to draw attention

  17. SpolSimilaritySearch - A web tool to compare and search similarities between spoligotypes of Mycobacterium tuberculosis complex.

    Science.gov (United States)

    Couvin, David; Zozio, Thierry; Rastogi, Nalin

    2017-07-01

    Spoligotyping is one of the most commonly used polymerase chain reaction (PCR)-based methods for identification and study of genetic diversity of Mycobacterium tuberculosis complex (MTBC). Despite its known limitations if used alone, the methodology is particularly useful when used in combination with other methods such as mycobacterial interspersed repetitive units - variable number of tandem DNA repeats (MIRU-VNTRs). At a worldwide scale, spoligotyping has allowed identification of information on 103,856 MTBC isolates (corresponding to 98049 clustered strains plus 5807 unique isolates from 169 countries of patient origin) contained within the SITVIT2 proprietary database of the Institut Pasteur de la Guadeloupe. The SpolSimilaritySearch web-tool described herein (available at: http://www.pasteur-guadeloupe.fr:8081/SpolSimilaritySearch) incorporates a similarity search algorithm allowing users to get a complete overview of similar spoligotype patterns (with information on presence or absence of 43 spacers) in the aforementioned worldwide database. This tool allows one to analyze spread and evolutionary patterns of MTBC by comparing similar spoligotype patterns, to distinguish between widespread, specific and/or confined patterns, as well as to pinpoint patterns with large deleted blocks, which play an intriguing role in the genetic epidemiology of M. tuberculosis. Finally, the SpolSimilaritySearch tool also provides with the country distribution patterns for each queried spoligotype. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Astrophysical techniques

    CERN Document Server

    Kitchin, CR

    2013-01-01

    DetectorsOptical DetectionRadio and Microwave DetectionX-Ray and Gamma-Ray DetectionCosmic Ray DetectorsNeutrino DetectorsGravitational Radiation Dark Matter and Dark Energy Detection ImagingThe Inverse ProblemPhotographyElectronic ImagingScanningInterferometrySpeckle InterferometryOccultationsRadarElectronic ImagesPhotometryPhotometryPhotometersSpectroscopySpectroscopy SpectroscopesOther TechniquesAstrometryPolarimetrySolar StudiesMagnetometryComputers and The Internet.

  19. Aseptic technique.

    Science.gov (United States)

    Bykowski, Tomasz; Stevenson, Brian

    2008-11-01

    This chapter describes common laboratory procedures that can reduce the risk of culture contaminations (sepsis), collectively referred as "aseptic technique." Two major strategies of aseptic work are described: using a Bunsen burner and a laminar flow hood. Both methods are presented in the form of general protocols applicable to a variety of laboratory tasks such as pipetting and dispensing aliquots, preparing growth media, and inoculating, passaging, and spreading microorganisms on petri dishes. Copyright 2008 by John Wiley & Sons, Inc.

  20. Presentation Technique

    International Nuclear Information System (INIS)

    Froejmark, M.

    1992-10-01

    The report presents a wide, easily understandable description of presentation technique and man-machine communication. General fundamentals for the man-machine interface are illustrated, and the factors that affect the interface are described. A model is presented for describing the operators work situation, based on three different levels in the operators behaviour. The operator reacts routinely in the face of simple, known problems, and reacts in accordance with predetermined plans in the face of more complex, recognizable problems. Deep fundamental knowledge is necessary for truly complex questions. Today's technical status and future development have been studied. In the future, the operator interface will be based on standard software. Functions such as zooming, integration of video pictures, and sound reproduction will become common. Video walls may be expected to come into use in situations in which several persons simultaneously need access to the same information. A summary of the fundamental rules for the design of good picture ergonomics and design requirements for control rooms are included in the report. In conclusion, the report describes a presentation technique within the Distribution Automation and Demand Side Management area and analyses the know-how requirements within Vattenfall. If different systems are integrated, such as geographical information systems and operation monitoring systems, strict demands are made on the expertise of the users for achieving a user-friendly technique which is matched to the needs of the human being. (3 figs.)

  1. Self-similarity in applied superconductivity

    International Nuclear Information System (INIS)

    Dresner, Lawrence

    1981-09-01

    Self-similarity is a descriptive term applying to a family of curves. It means that the family is invariant to a one-parameter group of affine (stretching) transformations. The property of self-similarity has been exploited in a wide variety of problems in applied superconductivity, namely, (i) transient distribution of the current among the filaments of a superconductor during charge-up, (ii) steady distribution of current among the filaments of a superconductor near the current leads, (iii) transient heat transfer in superfluid helium, (iv) transient diffusion in cylindrical geometry (important in studying the growth rate of the reacted layer in A15 materials), (v) thermal expulsion of helium from quenching cable-in-conduit conductors, (vi) eddy current heating of irregular plates by slow, ramped fields, and (vii) the specific heat of type-II superconductors. Most, but not all, of the applications involve differential equations, both ordinary and partial. The novel methods explained in this report should prove of great value in other fields, just as they already have done in applied superconductivity. (author)

  2. Similar Hamiltonian Between Avalanche-effect & Sociophysics

    Science.gov (United States)

    Maksoed, Ssi, Wh-

    2016-05-01

    Of similar Hamiltonian concerned in ``sociophysics'', there were RandomFieldIsingModel/RFIM in external field retrieved in S. Sabhapandit:``Hysteresis & Avalanche in RandomFieldIsingModel'',2002:'' ..in earthquake, it is an energy release and in case of ferromagnet, it is the size of the domain flips''. Following the extremes & compromises curve in Serge Galam: ``Sociophysics: a Review of Galam Model'', 2008 fig. 12, h 9 whereas it seems similar with ``heating curve''-Prof. Ir. Abdul Kadir: ``Mesin Arus Searah'', h 192 when the heat sources are continuous denote continuous opinion dynamics. Further, hysteresis as duties in ``Kajian Analisis Model Mikromagnetik dari Struktur Magnet Nanokomposit'', 2007 [ UI file no. S29286 ] also sought:'' calculate the probability that `one more site became unstable' causes an avalanche of the spin flips...'' usually found in Per Bak sand-pile fractal characters experiment exhibits. Great acknowledgment to HE. Mr. LieutGen-TNI[rtd]. H. TUK SETYOHADI, +62-21-7220385, Jl. Sriwijaya Raya 3, Kebayoran Baru, South-Jakarta.

  3. Similarity Reductions and Similarity Solutions of the (3+1)-Dimensional Kadomtsev-Petviashvili Equation

    Science.gov (United States)

    Liu, Na; Liu, Xi-Qiang

    2008-10-01

    Employing the compatibility method, we obtain the symmetries of the (3+1)-dimensional Kadomtsev-Petviashvili (KP) equation. Four types of similarity reductions of the KP equation are obtained by solving the corresponding characteristic equations associated with symmetry equations. In addition, a lot of similarity solutions to the KP equation are obtained.

  4. Ethical Use of Gestalt Techniques.

    Science.gov (United States)

    Given, Jane A.

    The purpose of this paper is to engender a healthy respect for Gestalt theory and techniques and the use of the techniques in the client's best interest and in the interest of positive professional and self-development in the practitioner. An overview of Gestalt techniques is provided, concentrating on the two category divisions of experiments and…

  5. Formulation of similarity porous media systems

    International Nuclear Information System (INIS)

    Anderson, R.M.; Ford, W.T.; Ruttan, A.; Strauss, M.J.

    1982-01-01

    The mathematical formulation of the Porous Media System (PMS) describing two-phase, immiscible, compressible fluid flow in linear, homogeneous porous media is reviewed and expanded. It is shown that families of common vertex, coaxial parabolas and families of parallel lines are the only families of curves on which solutions of the PMS may be constant. A coordinate transformation is used to change the partial differential equations of the PMS to a system of ordinary differential equations, referred to as a similarity Porous Media System (SPMS), in which the independent variable denotes movement from curve to curve in a selected family of curves. Properties of solutions of the first boundary value problem are developed for the SPMS

  6. Social Values as Arguments: Similar is Convincing

    Directory of Open Access Journals (Sweden)

    Gregory R Maio

    2014-08-01

    Full Text Available Politicians, philosophers, and rhetors engage in co-value argumentation: appealing to one value in order to support another value (e.g., equality leads to freedom. Across four experiments in the United Kingdom and India, we found that the psychological relatedness of values affects the persuasiveness of the arguments that bind them. Experiment 1 found that participants were more persuaded by arguments citing values that fulfilled similar motives than by arguments citing opposing values. Experiments 2 and 3 replicated this result using a wider variety of values, while finding that the effect is stronger among people higher in need for cognition and that the effect is mediated by the greater plausibility of co-value arguments that link motivationally compatible values. Experiment 4 extended the effect to real-world arguments taken from political propaganda and replicated the mediating effect of argument plausibility. The findings highlight the importance of value relatedness in argument persuasiveness.

  7. Social values as arguments: similar is convincing

    Science.gov (United States)

    Maio, Gregory R.; Hahn, Ulrike; Frost, John-Mark; Kuppens, Toon; Rehman, Nadia; Kamble, Shanmukh

    2014-01-01

    Politicians, philosophers, and rhetors engage in co-value argumentation: appealing to one value in order to support another value (e.g., “equality leads to freedom”). Across four experiments in the United Kingdom and India, we found that the psychological relatedness of values affects the persuasiveness of the arguments that bind them. Experiment 1 found that participants were more persuaded by arguments citing values that fulfilled similar motives than by arguments citing opposing values. Experiments 2 and 3 replicated this result using a wider variety of values, while finding that the effect is stronger among people higher in need for cognition and that the effect is mediated by the greater plausibility of co-value arguments that link motivationally compatible values. Experiment 4 extended the effect to real-world arguments taken from political propaganda and replicated the mediating effect of argument plausibility. The findings highlight the importance of value relatedness in argument persuasiveness. PMID:25147529

  8. Ubiquitin-binding proteins: similar, but different

    DEFF Research Database (Denmark)

    Andersen, Katrine M; Hofmann, Kay; Hartmann-Petersen, Rasmus

    2005-01-01

    of ubiquitin conjugation to endoplasmic reticulum degradation), UEV [ubiquitin E2 (ubiquitin-conjugating enzyme) variant] and NZF (nuclear protein localization gene 4 zinc finger) domain-containing proteins appear to have more specialized functions. Here we discuss functional and structural properties......Covalent modification of proteins with ubiquitin is a common regulatory mechanism in eukaryotic cells. Typically, ubiquitinated proteins are targeted for degradation by the 26 S proteasome. However, more recently the ubiquitin signal has also been connected with many other cell processes, including...... endocytosis, vesicle fusion, DNA repair and transcriptional silencing. Hence ubiquitination may be comparable with phosphorylation in its importance as an intracellular switch, controlling various signal-transduction pathways. Similar to the regulation of the extent of phosphorylation by kinases...

  9. Methods for Similarity-based Virtual Screening

    Directory of Open Access Journals (Sweden)

    Thomas Greve Kristensen

    2013-02-01

    Full Text Available Developing new medical drugs is expensive. Among the first steps is a screening process, in which molecules in existing chemical libraries are tested for activity against a given target. This requires a lot of resources and manpower. Therefore it has become common to perform a virtual screening, where computers are used for predicting the activity of very large libraries of molecules, to identify the most promising leads for further laboratory experiments. Since computer simulations generally require fewer resources than physical experimentation this can lower the cost of medical and biological research significantly. In this paper we review practically fast algorithms for screening databases of molecules in order to find molecules that are sufficiently similar to a query molecule.

  10. METHODS FOR SIMILARITY-BASED VIRTUAL SCREENING

    Directory of Open Access Journals (Sweden)

    Thomas G. Kristensen

    2013-02-01

    Full Text Available Developing new medical drugs is expensive. Among the first steps is a screening process, in which molecules in existing chemical libraries are tested for activity against a given target. This requires a lot of resources and manpower. Therefore it has become common to perform a virtual screening, where computers are used for predicting the activity of very large libraries of molecules, to identify the most promising leads for further laboratory experiments. Since computer simulations generally require fewer resources than physical experimentation this can lower the cost of medical and biological research significantly. In this paper we review practically fast algorithms for screening databases of molecules in order to find molecules that are sufficiently similar to a query molecule.

  11. A Lithium Vapor Box Divertor Similarity Experiment

    Science.gov (United States)

    Cohen, Robert A.; Emdee, Eric D.; Goldston, Robert J.; Jaworski, Michael A.; Schwartz, Jacob A.

    2017-10-01

    A lithium vapor box divertor offers an alternate means of managing the extreme power density of divertor plasmas by leveraging gaseous lithium to volumetrically extract power. The vapor box divertor is a baffled slot with liquid lithium coated walls held at temperatures which increase toward the divertor floor. The resulting vapor pressure differential drives gaseous lithium from hotter chambers into cooler ones, where the lithium condenses and returns. A similarity experiment was devised to investigate the advantages offered by a vapor box divertor design. We discuss the design, construction, and early findings of the vapor box divertor experiment including vapor can construction, power transfer calculations, joint integrity tests, and thermocouple data logging. Heat redistribution of an incident plasma-based heat flux from a typical linear plasma device is also presented. This work supported by DOE Contract No. DE-AC02-09CH11466 and The Princeton Environmental Institute.

  12. Three Journal Similarity Metrics and Their Application to Biomedical Journals

    Science.gov (United States)

    D′Souza, Jennifer L.; Smalheiser, Neil R.

    2014-01-01

    In the present paper, we have created several novel journal similarity metrics. The MeSH odds ratio measures the topical similarity of any pair of journals, based on the major MeSH headings assigned to articles in MEDLINE. The second metric employed the 2009 Author-ity author name disambiguation dataset as a gold standard for estimating the author odds ratio. This gives a straightforward, intuitive answer to the question: Given two articles in PubMed that share the same author name (lastname, first initial), how does knowing only the identity of the journals (in which the articles were published) predict the relative likelihood that they are written by the same person vs. different persons? The article pair odds ratio detects the tendency of authors to publish repeatedly in the same journal, as well as in specific pairs of journals. The metrics can be applied not only to estimate the similarity of a pair of journals, but to provide novel profiles of individual journals as well. For example, for each journal, one can define the MeSH cloud as the number of other journals that are topically more similar to it than expected by chance, and the author cloud as the number of other journals that share more authors than expected by chance. These metrics for journal pairs and individual journals have been provided in the form of public datasets that can be readily studied and utilized by others. PMID:25536326

  13. Three journal similarity metrics and their application to biomedical journals.

    Science.gov (United States)

    D'Souza, Jennifer L; Smalheiser, Neil R

    2014-01-01

    In the present paper, we have created several novel journal similarity metrics. The MeSH odds ratio measures the topical similarity of any pair of journals, based on the major MeSH headings assigned to articles in MEDLINE. The second metric employed the 2009 Author-ity author name disambiguation dataset as a gold standard for estimating the author odds ratio. This gives a straightforward, intuitive answer to the question: Given two articles in PubMed that share the same author name (lastname, first initial), how does knowing only the identity of the journals (in which the articles were published) predict the relative likelihood that they are written by the same person vs. different persons? The article pair odds ratio detects the tendency of authors to publish repeatedly in the same journal, as well as in specific pairs of journals. The metrics can be applied not only to estimate the similarity of a pair of journals, but to provide novel profiles of individual journals as well. For example, for each journal, one can define the MeSH cloud as the number of other journals that are topically more similar to it than expected by chance, and the author cloud as the number of other journals that share more authors than expected by chance. These metrics for journal pairs and individual journals have been provided in the form of public datasets that can be readily studied and utilized by others.

  14. Human vs. Mouse Nociceptors - Similarities and Differences.

    Science.gov (United States)

    Rostock, Charlotte; Schrenk-Siemens, Katrin; Pohle, Jörg; Siemens, Jan

    2017-12-08

    The somatosensory system allows us to detect a diverse range of physical and chemical stimuli including noxious ones, which can initiate protective reflexes to prevent tissue damage. However, the sensation of pain can - under pathological circumstances - outlive its usefulness and perpetrate ongoing suffering. Rodent model systems have been tremendously useful to help understand basic mechanisms of pain perception. Unfortunately, the translation of this knowledge into novel therapies has been challenging. We have investigated similarities and differences of human and mouse peptidergic (TRKA expressing) nociceptors using dual-color fluorescence in situ hybridization of dorsal root ganglia. By comparing the transcripts of a selected group of well-established nociceptive markers, we observed significant differences for some of them. We found co-expression of Trpv1, a key player for sensitization and inflammatory pain, with TrkA in a larger population in humans compared to mice. Similar results could be obtained for Na v 1.8 and Na v 1.9, two voltage gated sodium channels implicated in pathological forms of pain. Additionally, co-expression of Ret and TrkA was also found to be more abundant in human neurons. Moreover, the neurofilament heavy polypeptide was detected in all human sensory DRG neurons compared to a more selective expression pattern observed in rodents. To our knowledge, this is the first time that such detailed comparative analysis has been performed and we believe that our findings will direct future experimentation geared to understand the difficulties we face in translating findings from rodent models to humans. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Link-Based Similarity Measures Using Reachability Vectors

    Directory of Open Access Journals (Sweden)

    Seok-Ho Yoon

    2014-01-01

    Full Text Available We present a novel approach for computing link-based similarities among objects accurately by utilizing the link information pertaining to the objects involved. We discuss the problems with previous link-based similarity measures and propose a novel approach for computing link based similarities that does not suffer from these problems. In the proposed approach each target object is represented by a vector. Each element of the vector corresponds to all the objects in the given data, and the value of each element denotes the weight for the corresponding object. As for this weight value, we propose to utilize the probability of reaching from the target object to the specific object, computed using the “Random Walk with Restart” strategy. Then, we define the similarity between two objects as the cosine similarity of the two vectors. In this paper, we provide examples to show that our approach does not suffer from the aforementioned problems. We also evaluate the performance of the proposed methods in comparison with existing link-based measures, qualitatively and quantitatively, with respect to two kinds of data sets, scientific papers and Web documents. Our experimental results indicate that the proposed methods significantly outperform the existing measures.

  16. Networks of plants: how to measure similarity in vegetable species

    Science.gov (United States)

    Vivaldo, Gianna; Masi, Elisa; Pandolfi, Camilla; Mancuso, Stefano; Caldarelli, Guido

    2016-06-01

    Despite the common misconception of nearly static organisms, plants do interact continuously with the environment and with each other. It is fair to assume that during their evolution they developed particular features to overcome similar problems and to exploit possibilities from environment. In this paper we introduce various quantitative measures based on recent advancements in complex network theory that allow to measure the effective similarities of various species. By using this approach on the similarity in fruit-typology ecological traits we obtain a clear plant classification in a way similar to traditional taxonomic classification. This result is not trivial, since a similar analysis done on the basis of diaspore morphological properties do not provide any clear parameter to classify plants species. Complex network theory can then be used in order to determine which feature amongst many can be used to distinguish scope and possibly evolution of plants. Future uses of this approach range from functional classification to quantitative determination of plant communities in nature.

  17. Geography and similarity of regional cuisines in China.

    Directory of Open Access Journals (Sweden)

    Yu-Xiao Zhu

    Full Text Available Food occupies a central position in every culture and it is therefore of great interest to understand the evolution of food culture. The advent of the World Wide Web and online recipe repositories have begun to provide unprecedented opportunities for data-driven, quantitative study of food culture. Here we harness an online database documenting recipes from various Chinese regional cuisines and investigate the similarity of regional cuisines in terms of geography and climate. We find that geographical proximity, rather than climate proximity, is a crucial factor that determines the similarity of regional cuisines. We develop a model of regional cuisine evolution that provides helpful clues for understanding the evolution of cuisines and cultures.

  18. Geography and Similarity of Regional Cuisines in China

    Science.gov (United States)

    Zhu, Yu-Xiao; Huang, Junming; Zhang, Zi-Ke; Zhang, Qian-Ming; Zhou, Tao; Ahn, Yong-Yeol

    2013-01-01

    Food occupies a central position in every culture and it is therefore of great interest to understand the evolution of food culture. The advent of the World Wide Web and online recipe repositories have begun to provide unprecedented opportunities for data-driven, quantitative study of food culture. Here we harness an online database documenting recipes from various Chinese regional cuisines and investigate the similarity of regional cuisines in terms of geography and climate. We find that geographical proximity, rather than climate proximity, is a crucial factor that determines the similarity of regional cuisines. We develop a model of regional cuisine evolution that provides helpful clues for understanding the evolution of cuisines and cultures. PMID:24260166

  19. Terahertz Techniques

    CERN Document Server

    Bründermann, Erik; Kimmitt, Maurice FitzGerald

    2012-01-01

    Research and development in the terahertz portion of the electromagnetic spectrum has expanded very rapidly during the past fifteen years due to major advances in sources, detectors and instrumentation. Many scientists and engineers are entering the field and this volume offers a comprehensive and integrated treatment of all aspects of terahertz technology. The three authors, who have been active researchers in this region over a number of years, have designed Terahertz Techniques to be both a general introduction to the subject and a definitive reference resource for all those involved in this exciting research area.

  20. Extending the similarity-based XML multicast approach with digital signatures

    DEFF Research Database (Denmark)

    Azzini, Antonia; Marrara, Stefania; Jensen, Meiko

    2009-01-01

    This paper investigates the interplay between similarity-based SOAP message aggregation and digital signature application. An overview on the approaches resulting from the different orders for the tasks of signature application, verification, similarity aggregation and splitting is provided. Depe...

  1. Copywriting and Newswriting Need Similar Skills.

    Science.gov (United States)

    McAdams, Kathy; Sweeney, John

    1987-01-01

    Claims that newswriting practice contributes to the development of advertising writing skills and that it is particularly relevant given the increasing enrollment in advertising programs. Describes five factors common to both news and advertising writing: audience, distillation, freshness, substance, and easy access. Provides examples of each…

  2. Statistical Similarity Based Change Detection for Multitemporal Remote Sensing Images

    Directory of Open Access Journals (Sweden)

    Mumu Aktar

    2017-01-01

    Full Text Available Change detection (CD of any surface using multitemporal remote sensing images is an important research topic since up-to-date information about earth surface is of great value. Abrupt changes are occurring in different earth surfaces due to natural disasters or man-made activities which cause damage to that place. Therefore, it is necessary to observe the changes for taking necessary steps to recover the subsequent damage. This paper is concerned with this issue and analyzes statistical similarity measure to perform CD using remote sensing images of the same scene taken at two different dates. A variation of normalized mutual information (NMI as a similarity measure has been developed here using sliding window of different sizes. In sliding window approach, pixels’ local neighborhood plays a significant role in computing the similarity compared to the whole image. Thus the insignificant global characteristics containing noise and sparse samples can be avoided when evaluating the probability density function. Therefore, NMI with different window sizes is proposed here to identify changes using multitemporal data. Experiments have been carried out using two separate multitemporal remote sensing images captured one year apart and one month apart, respectively. Experimental analysis reveals that the proposed technique can detect up to 97.71% of changes which outperforms the traditional approaches.

  3. Novel expansion techniques for skin grafts

    Science.gov (United States)

    Kadam, Dinesh

    2016-01-01

    The quest for skin expansion is not restricted to cover a large area alone, but to produce acceptable uniform surfaces, robust engraftment to withstand mechanical shear and infection, with a minimal donor morbidity. Ease of the technique, shorter healing period and reproducible results are essential parameters to adopt novel techniques. Significant advances seen in four fronts of autologous grafting are: (1) Dermal–epidermal graft expansion techniques, (2) epidermal graft harvests technique, (3) melanocyte-rich basal cell therapy for vitiligo and (4) robust and faster autologous cell cultures. Meek's original concept that the sum of perimeter of smaller grafts is larger than the harvested graft, and smaller the graft size, the greater is the potential for regeneration is witnessed in newer modification. Further, as graft size becomes smaller or minced, these micrografts can survive on the wound bed exudate irrespective of their dermal orientation. Expansion produced by 4 mm × 4 mm sized Meek micrografts is 10-folds, similarly 0.8 mm × 0.8 mm size micrografts produce 100-fold expansion, which becomes 700-fold with pixel grafts of 0.3 mm × 0.3 mm size. Fractional skin harvest is another new technique with 700 μ size full thickness graft. These provide instant autologous non-cultured graft to cover extensive areas with similar quality of engraftment surface as split skin grafts. Newer tools for epidermal blister graft harvest quickly, with uniform size to produce 7-fold expansions with reproducible results. In addition, donor area heals faster with minimal scar. Melanocyte-rich cell suspension is utilised in vitiligo surgery tapping the potential of hair root melanocytes. Further advances in the cell culture to reduce the cultivation time and provide stronger epidermal sheets with dermal carrier are seen in trials. PMID:27274117

  4. [New microbiological techniques].

    Science.gov (United States)

    Schubert, S; Wieser, A; Bonkat, G

    2017-06-01

    Microbiological diagnostic procedures have changed rapidly in recent years. This is especially true in the field of molecular diagnostics. Classical culture-based techniques are still the gold standard in many areas; however, they are already complemented by automated and also molecular techniques to guarantee faster and better quality results. The most commonly used techniques include real-time polymerase chain reaction (RT-PCR) based systems and nucleic acid hybridization. These procedures are used most powerfully from direct patient samples or in assays to detect the presence of nonculturable or fastidious organisms. Further techniques such as DNA sequencing are not yet used routinely for urological samples and can be considered experimental. However, in conjunction with dropping prices and further technical developments, these techniques promise to be used much more in the near future. Regarding bacterial identification from culture, mass spectrometry (MALDI-TOF MS) has become the technique of choice in recent years especially in Europe. It has tremendously shortened the time to result. This is now going to be extended to antibiotic susceptibility testing. This is of paramount importance in view of ever rising antimicrobial resistance rates. Techniques described in this review offer a faster and better microbiological diagnosis. Such continuous improvements are critical especially in times of cost pressure and rising antimicrobial resistance rates. It is in our interest to provide the best possible care for patients and in this regard a good and effective communication between the laboratory and the clinician is of vital importance.

  5. Similarity of eigenstates in generalized labyrinth tilings

    International Nuclear Information System (INIS)

    Thiem, Stefanie; Schreiber, Michael

    2010-01-01

    The eigenstates of d-dimensional quasicrystalline models with a separable Hamiltonian are studied within the tight-binding model. The approach is based on mathematical sequences, constructed by an inflation rule P = {w → s,s → sws b-1 } describing the weak/strong couplings of atoms in a quasiperiodic chain. Higher-dimensional quasiperiodic tilings are constructed as a direct product of these chains and their eigenstates can be directly calculated by multiplying the energies E or wave functions ψ of the chain, respectively. Applying this construction rule, the grid in d dimensions splits into 2 d-1 different tilings, for which we investigated the characteristics of the wave functions. For the standard two-dimensional labyrinth tiling constructed from the octonacci sequence (b = 2) the lattice breaks up into two identical lattices, which consequently yield the same eigenstates. While this is not the case for b ≠ 2, our numerical results show that the wave functions of the different grids become increasingly similar for large system sizes. This can be explained by the fact that the structure of the 2 d-1 grids mainly differs at the boundaries and thus for large systems the eigenstates approach each other. This property allows us to analytically derive properties of the higher-dimensional generalized labyrinth tilings from the one-dimensional results. In particular participation numbers and corresponding scaling exponents have been determined.

  6. State and Mafia, Differences and Similarities

    Directory of Open Access Journals (Sweden)

    Alfano Vincenzo

    2015-02-01

    Full Text Available The purpose of this article is to investigate about the differences and, if any, the similarities among the modern State and the mafia criminal organizations. In particular, starting from their definitions, I will try to find the differences between State and mafia, to then focus on the operational aspects of the functioning of these two organizations, with specific reference to the effect/impact that both these human constructs have on citizens’ existences, and especially on citizen’s economic lives. All this in order to understand whether it is possible to identify an objective difference – beside morals – between taxation by the modern State and extortion by criminal organizations. With this of course I do not want to argue that the mafia is in any way justifiable or absolvable, nor that it is better than the State. However, I want to investigate whether there is a real, logical reason why the State should be considered by the citizens more desirable than the criminal organizations oppressing Southern Italy, from a strictly logical point of view and not from the point of view of ethics and morality.

  7. Multidimensional Scaling Visualization Using Parametric Similarity Indices

    Directory of Open Access Journals (Sweden)

    J. A. Tenreiro Machado

    2015-03-01

    Full Text Available In this paper, we apply multidimensional scaling (MDS and parametric similarity indices (PSI in the analysis of complex systems (CS. Each CS is viewed as a dynamical system, exhibiting an output time-series to be interpreted as a manifestation of its behavior. We start by adopting a sliding window to sample the original data into several consecutive time periods. Second, we define a given PSI for tracking pieces of data. We then compare the windows for different values of the parameter, and we generate the corresponding MDS maps of ‘points’. Third, we use Procrustes analysis to linearly transform the MDS charts for maximum superposition and to build a globalMDS map of “shapes”. This final plot captures the time evolution of the phenomena and is sensitive to the PSI adopted. The generalized correlation, theMinkowski distance and four entropy-based indices are tested. The proposed approach is applied to the Dow Jones Industrial Average stock market index and the Europe Brent Spot Price FOB time-series.

  8. Genetic and 'cultural' similarity in wild chimpanzees.

    Science.gov (United States)

    Langergraber, Kevin E; Boesch, Christophe; Inoue, Eiji; Inoue-Murayama, Miho; Mitani, John C; Nishida, Toshisada; Pusey, Anne; Reynolds, Vernon; Schubert, Grit; Wrangham, Richard W; Wroblewski, Emily; Vigilant, Linda

    2011-02-07

    The question of whether animals possess 'cultures' or 'traditions' continues to generate widespread theoretical and empirical interest. Studies of wild chimpanzees have featured prominently in this discussion, as the dominant approach used to identify culture in wild animals was first applied to them. This procedure, the 'method of exclusion,' begins by documenting behavioural differences between groups and then infers the existence of culture by eliminating ecological explanations for their occurrence. The validity of this approach has been questioned because genetic differences between groups have not explicitly been ruled out as a factor contributing to between-group differences in behaviour. Here we investigate this issue directly by analysing genetic and behavioural data from nine groups of wild chimpanzees. We find that the overall levels of genetic and behavioural dissimilarity between groups are highly and statistically significantly correlated. Additional analyses show that only a very small number of behaviours vary between genetically similar groups, and that there is no obvious pattern as to which classes of behaviours (e.g. tool-use versus communicative) have a distribution that matches patterns of between-group genetic dissimilarity. These results indicate that genetic dissimilarity cannot be eliminated as playing a major role in generating group differences in chimpanzee behaviour.

  9. Different-but-Similar Judgments by Bumblebees

    Directory of Open Access Journals (Sweden)

    Vicki Xu

    2016-08-01

    Full Text Available This study examines picture perception in an invertebrate. Two questions regarding possible picture-object correspondence are addressed for bumblebees (Bombus impatiens: (1 Do bees perceive the difference between an object and its corresponding picture even when they have not been trained to do so? (2 Do they also perceive the similarity? Twenty bees from each of four colonies underwent discrimination training of stimuli placed in a radial maze. Bees were trained to discriminate between two objects (artificial flowers in one group and between photos of those objects in another. Subsequent testing on unrewarding stimuli revealed, for both groups, a significant discrimination between the object and its photo: discrimination training was not necessary for bees to detect a difference between corresponding objects and pictures. We obtained not only object-to-picture transfer, as in previous research, but also the reverse: picture-to-object transfer. In the absence of the rewarding object, its photo, though never seen before by the bees, was accepted as a substitute. The reverse was also true. Bumblebees treated pictures as “different-but-similar” without having been trained to do so, which is in turn useful in floral categorization.

  10. Popularity, similarity, and the network extraversion bias.

    Science.gov (United States)

    Feiler, Daniel C; Kleinbaum, Adam M

    2015-05-01

    Using the emergent friendship network of an incoming cohort of students in an M.B.A. program, we examined the role of extraversion in shaping social networks. Extraversion has two important implications for the emergence of network ties: a popularity effect, in which extraverts accumulate more friends than introverts do, and a homophily effect, in which the more similar are two people's levels of extraversion, the more likely they are to become friends. These effects result in a systematic network extraversion bias, in which people's social networks will tend to be overpopulated with extraverts and underpopulated with introverts. Moreover, the most extraverted people have the greatest network extraversion bias, and the most introverted people have the least network extraversion bias. Our finding that social networks were systematically misrepresentative of the broader social environment raises questions about whether there is a societal bias toward believing other people are more extraverted than they actually are and whether introverts are better socially calibrated than extraverts. © The Author(s) 2015.

  11. Exploring similarities among many species distributions

    Science.gov (United States)

    Simmerman, Scott; Wang, Jingyuan; Osborne, James; Shook, Kimberly; Huang, Jian; Godsoe, William; Simons, Theodore R.

    2012-01-01

    Collecting species presence data and then building models to predict species distribution has been long practiced in the field of ecology for the purpose of improving our understanding of species relationships with each other and with the environment. Due to limitations of computing power as well as limited means of using modeling software on HPC facilities, past species distribution studies have been unable to fully explore diverse data sets. We build a system that can, for the first time to our knowledge, leverage HPC to support effective exploration of species similarities in distribution as well as their dependencies on common environmental conditions. Our system can also compute and reveal uncertainties in the modeling results enabling domain experts to make informed judgments about the data. Our work was motivated by and centered around data collection efforts within the Great Smoky Mountains National Park that date back to the 1940s. Our findings present new research opportunities in ecology and produce actionable field-work items for biodiversity management personnel to include in their planning of daily management activities.

  12. Body odor similarity in noncohabiting twins.

    Science.gov (United States)

    Roberts, S Craig; Gosling, L Morris; Spector, Tim D; Miller, Paul; Penn, Dustin J; Petrie, Marion

    2005-10-01

    There is currently considerable interest in biometric approaches using human odor as a marker of disease or genetic individuality. Body odor is also thought to be used during mate choice to select genetically compatible mates. The idea that body odor reveals information about both genetic identity and genetic similarity is most readily tested by examining odor in twin pairs. However, although this idea can be traced back 130 years to Francis Galton in 1875, most studies using dogs fail to control for shared environmental effects associated with cohabitation. Here we show that odors of identical twins (but not dizygotic twins) can be matched by human sniffers at rates better than chance, even when the twins are living apart. In addition, matching frequencies for identical twin odors were not significantly different from those for duplicate odors from the same individual. These results indicate an important genetic influence on body odor and the potential for developing technologies for human odor printing in relation to underlying genotype.

  13. Algorithms Design Techniques and Analysis

    CERN Document Server

    Alsuwaiyel, M H

    1999-01-01

    Problem solving is an essential part of every scientific discipline. It has two components: (1) problem identification and formulation, and (2) solution of the formulated problem. One can solve a problem on its own using ad hoc techniques or follow those techniques that have produced efficient solutions to similar problems. This requires the understanding of various algorithm design techniques, how and when to use them to formulate solutions and the context appropriate for each of them. This book advocates the study of algorithm design techniques by presenting most of the useful algorithm desi

  14. Coupled-cluster representation of Green function employing modified spectral resolutions of similarity transformed Hamiltonians

    International Nuclear Information System (INIS)

    Kowalski, K.; Bhaskaran-Nair, K.; Shelton, W. A.

    2014-01-01

    In this paper we discuss a new formalism for producing an analytic coupled-cluster (CC) Green's function for an N-electron system by shifting the poles of similarity transformed Hamiltonians represented in N − 1 and N + 1 electron Hilbert spaces. Simple criteria are derived for the states in N − 1 and N + 1 electron spaces that are then corrected in the spectral resolution of the corresponding matrix representations of the similarity transformed Hamiltonian. The accurate description of excited state processes within a Green's function formalism would be of significant importance to a number of scientific communities ranging from physics and chemistry to engineering and the biological sciences. This is because the Green's function methodology provides a direct path for not only calculating properties whose underlying origins come from coupled many-body interactions but also provides a straightforward path for calculating electron transport, response, and correlation functions that allows for a direct link with experiment. As a special case of this general formulation, we discuss the application of this technique for Green's function defined by the CC with singles and doubles representation of the ground-state wave function

  15. Similarity and symmetry methods applications in elasticity and mechanics of materials

    CERN Document Server

    Mladenov, Ivaïlo

    2014-01-01

    The principle aim of the book is to present a self-contained, modern account of similarity and symmetry methods, which are important mathematical tools for both physicists, engineers and applied mathematicians. The idea is to provide a balanced presentation of the mathematical techniques and applications of symmetry methods in mathematics, physics and engineering. That is why it includes recent developments and many examples in finding systematically conservation laws, local and nonlocal symmetries for ordinary and partial differential equations. The role of continuous symmetries in classical and quantum field theories is exposed at a technical level accessible even for non specialists. The importance of symmetries in continuum mechanics and mechanics of materials is highlighted through recent developments, such as the construction of constitutive models for various materials combining Lie symmetries with experimental data. As a whole this book is a unique collection of contributions from experts in the field...

  16. Similarly shaped letters evoke similar colors in grapheme-color synesthesia.

    Science.gov (United States)

    Brang, David; Rouw, Romke; Ramachandran, V S; Coulson, Seana

    2011-04-01

    Grapheme-color synesthesia is a neurological condition in which viewing numbers or letters (graphemes) results in the concurrent sensation of color. While the anatomical substrates underlying this experience are well understood, little research to date has investigated factors influencing the particular colors associated with particular graphemes or how synesthesia occurs developmentally. A recent suggestion of such an interaction has been proposed in the cascaded cross-tuning (CCT) model of synesthesia, which posits that in synesthetes connections between grapheme regions and color area V4 participate in a competitive activation process, with synesthetic colors arising during the component-stage of grapheme processing. This model more directly suggests that graphemes sharing similar component features (lines, curves, etc.) should accordingly activate more similar synesthetic colors. To test this proposal, we created and regressed synesthetic color-similarity matrices for each of 52 synesthetes against a letter-confusability matrix, an unbiased measure of visual similarity among graphemes. Results of synesthetes' grapheme-color correspondences indeed revealed that more similarly shaped graphemes corresponded with more similar synesthetic colors, with stronger effects observed in individuals with more intense synesthetic experiences (projector synesthetes). These results support the CCT model of synesthesia, implicate early perceptual mechanisms as driving factors in the elicitation of synesthetic hues, and further highlight the relationship between conceptual and perceptual factors in this phenomenon. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Helical tomotherapy provides efficacy similar to that of intensity-modulated radiation therapy with dosimetric benefits for endometrial carcinoma

    Directory of Open Access Journals (Sweden)

    Hsieh CH

    2012-10-01

    Full Text Available Chen-Hsi Hsieh,1,4–6 Pei-Wei Shueng,1,3 Sheng-Mou Hsiao,2 Ming-Chow Wei,2 Wen-Yih Wu,2 Hsu-Dong Sun,2 Hui-Ju Tien,1 Li-Ying Wang,7 Yen-Ping Hsieh81Division of Radiation Oncology, Department of Radiology, 2Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, New Taipei City, 3Department of Radiation Oncology, National Defense Medical Center, 4Department of Medicine, 5Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, 6Oriental Institute of Technology, New Taipei City, 7School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, 8Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung, Taiwan, ChinaBackground: The purpose of this study was to compare the efficacy of intensity-modulated radiotherapy (IMRT and helical tomotherapy for endometrial cancer.Methods: Between November 1, 2006 and November 31, 2010, 31 patients with histologically confirmed endometrial cancer were enrolled. All enrolled patients received total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant whole pelvic IMRT or helical tomotherapy.Results: The actuarial 3-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates for the IMRT and helical tomotherapy groups were 87.5% versus 100%, 91.7% versus 51.7%, 91.7% versus 83.3%, and 91.7% versus 51.7%, respectively. The conformal index and uniformity index for IMRT versus helical tomotherapy was 1.25 versus 1.17 (P = 0.04 and 1.08 versus 1.05 (P < 0.01, respectively. Two of 31 patients with cervical stump failure were noted, one in the IMRT group and the other in the helical tomotherapy group. No acute or late grade 3 or 4 toxicities were noted, including proctitis, or genitourinary or gastrointestinal disturbances.Conclusion: Helical tomotherapy is as effective as IMRT and has better uniformity and conformal indices, and critical organ-sparing properties. Prospective clinical trials are needed to evaluate the comparative efficacy of IMRT versus helical tomotherapy.Keywords: endometrial cancer, helical tomotherapy, intensity-modulated radiotherapy

  18. Just-About-Right and ideal scaling provide similar insights into the influence of sensory attributes on liking.

    Science.gov (United States)

    Li, Bangde; Hayes, John E; Ziegler, Gregory R

    2014-10-01

    Just-about-right (JAR) scaling is criticized for measuring attribute intensity and acceptability simultaneously. Using JAR scaling, an attribute is evaluated for its appropriateness relative to one's hypothetical ideal level that is pre-defined at the middle of a continuum. Alternatively, ideal scaling measures these two constructs separately. Ideal scaling allows participants to rate their ideal freely on the scale (i.e., without assuming the "Too Little" and "Too Much" regions are equal in size). We hypothesized that constraining participants' ideal to the center point, as is done in the JAR scale, may cause a scaling bias and, thereby, influence the magnitude of "Too Little" and "Too Much". Furthermore, we hypothesized that the magnitude of "Too Little" and "Too Much" would influence liking to different extents. Coffee-flavored dairy beverages (n=20) were formulated using a fractional, constrained-mixture design that varied the ratio of water, milk, coffee extract, and sucrose. Participants tasted 4 of 20 prototypes that were served in a monadic sequential order using a balanced incomplete block design. Data reported here are for participants randomly assigned to one of two research conditions: ideal scaling (n=129) or JAR scaling (n=132). For both conditions, participants rated overall liking using a 9-point hedonic scale. Four attributes ( sweetness, milk flavor, coffee flavor and thickness ) were evaluated. The reliability of an individual participant's ideal rating for an attribute was evaluated using the standard deviation of their ideal ratings (n=4). All data from a participant were eliminated from further analyses when his/her standard deviation of the ideal ratings for any of the four rated attributes was identified as a statistical outlier. This resulted in the elimination of 15 of 129 (12 %) of participants in the ideal scaling group. Multiple linear regression was employed to model liking as a function of "Too Little" or "Too Much" attribute intensities. Mean ideal ratings (averaged across participants) for all four attributes were significantly different from the central point of the scale (i.e., 50). However, Coffee flavor was the only attribute for which the mean ideal rating (57.2) fell outside the central 10% (45.0-55.0). Even so, the magnitude of "Too Little" and "Too Much" was not affected by the scaling method. The influence of the magnitude of "Too Little" and "Too Much" on liking was asymmetrical. Both scaling methods agreed that sweetness and coffee flavor were the main sensory attributes affecting liking . Overall, JAR scaling and ideal scaling were comparable for measuring "Too Little" and "Too Much", and identifying the main factors affecting liking.

  19. Native and non-native plants provide similar refuge to invertebrate prey, but less than artificial plants

    NARCIS (Netherlands)

    Grutters, Bart; Pollux, B.J.A.; Verberk, W.C.E.P.; Bakker, E.S.

    2015-01-01

    Non-native species introductions are widespread and can affect ecosystem functioning by altering the structure of food webs. Invading plants often modify habitat structure, which may affect the suitability of vegetation as refuge and could thus impact predator-prey dynamics. Yet little is known

  20. Missing data in longitudinal studies: cross-sectional multiple imputation provides similar estimates to full-information maximum likelihood.

    Science.gov (United States)

    Ferro, Mark A

    2014-01-01

    The aim of this research was to examine, in an exploratory manner, whether cross-sectional multiple imputation generates valid parameter estimates for a latent growth curve model in a longitudinal data set with nonmonotone missingness. A simulated longitudinal data set of N = 5000 was generated and consisted of a continuous dependent variable, assessed at three measurement occasions and a categorical time-invariant independent variable. Missing data had a nonmonotone pattern and the proportion of missingness increased from the initial to the final measurement occasion (5%-20%). Three methods were considered to deal with missing data: listwise deletion, full-information maximum likelihood, and multiple imputation. A latent growth curve model was specified and analysis of variance was used to compare parameter estimates between the full data set and missing data approaches. Multiple imputation resulted in significantly lower slope variance compared with the full data set. There were no differences in any parameter estimates between the multiple imputation and full-information maximum likelihood approaches. This study suggested that in longitudinal studies with nonmonotone missingness, cross-sectional imputation at each time point may be viable and produces estimates comparable with those obtained with full-information maximum likelihood. Future research pursuing the validity of this method is warranted. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Combinatorial techniques

    CERN Document Server

    Sane, Sharad S

    2013-01-01

    This is a basic text on combinatorics that deals with all the three aspects of the discipline: tricks, techniques and theory, and attempts to blend them. The book has several distinctive features. Probability and random variables with their interconnections to permutations are discussed. The theme of parity has been specially included and it covers applications ranging from solving the Nim game to the quadratic reciprocity law. Chapters related to geometry include triangulations and Sperner's theorem, classification of regular polytopes, tilings and an introduction to the Eulcidean Ramsey theory. Material on group actions covers Sylow theory, automorphism groups and a classification of finite subgroups of orthogonal groups. All chapters have a large number of exercises with varying degrees of difficulty, ranging from material suitable for Mathematical Olympiads to research.

  2. Understanding similarity of groundwater systems with empirical copulas

    Science.gov (United States)

    Haaf, Ezra; Kumar, Rohini; Samaniego, Luis; Barthel, Roland

    2016-04-01

    Within the classification framework for groundwater systems that aims for identifying similarity of hydrogeological systems and transferring information from a well-observed to an ungauged system (Haaf and Barthel, 2015; Haaf and Barthel, 2016), we propose a copula-based method for describing groundwater-systems similarity. Copulas are an emerging method in hydrological sciences that make it possible to model the dependence structure of two groundwater level time series, independently of the effects of their marginal distributions. This study is based on Samaniego et al. (2010), which described an approach calculating dissimilarity measures from bivariate empirical copula densities of streamflow time series. Subsequently, streamflow is predicted in ungauged basins by transferring properties from similar catchments. The proposed approach is innovative because copula-based similarity has not yet been applied to groundwater systems. Here we estimate the pairwise dependence structure of 600 wells in Southern Germany using 10 years of weekly groundwater level observations. Based on these empirical copulas, dissimilarity measures are estimated, such as the copula's lower- and upper corner cumulated probability, copula-based Spearman's rank correlation - as proposed by Samaniego et al. (2010). For the characterization of groundwater systems, copula-based metrics are compared with dissimilarities obtained from precipitation signals corresponding to the presumed area of influence of each groundwater well. This promising approach provides a new tool for advancing similarity-based classification of groundwater system dynamics. Haaf, E., Barthel, R., 2015. Methods for assessing hydrogeological similarity and for classification of groundwater systems on the regional scale, EGU General Assembly 2015, Vienna, Austria. Haaf, E., Barthel, R., 2016. An approach for classification of hydrogeological systems at the regional scale based on groundwater hydrographs EGU General Assembly

  3. Expanding the boundaries of local similarity analysis.

    Science.gov (United States)

    Durno, W Evan; Hanson, Niels W; Konwar, Kishori M; Hallam, Steven J

    2013-01-01

    Pairwise comparison of time series data for both local and time-lagged relationships is a computationally challenging problem relevant to many fields of inquiry. The Local Similarity Analysis (LSA) statistic identifies the existence of local and lagged relationships, but determining significance through a p-value has been algorithmically cumbersome due to an intensive permutation test, shuffling rows and columns and repeatedly calculating the statistic. Furthermore, this p-value is calculated with the assumption of normality -- a statistical luxury dissociated from most real world datasets. To improve the performance of LSA on big datasets, an asymptotic upper bound on the p-value calculation was derived without the assumption of normality. This change in the bound calculation markedly improved computational speed from O(pm²n) to O(m²n), where p is the number of permutations in a permutation test, m is the number of time series, and n is the length of each time series. The bounding process is implemented as a computationally efficient software package, FASTLSA, written in C and optimized for threading on multi-core computers, improving its practical computation time. We computationally compare our approach to previous implementations of LSA, demonstrate broad applicability by analyzing time series data from public health, microbial ecology, and social media, and visualize resulting networks using the Cytoscape software. The FASTLSA software package expands the boundaries of LSA allowing analysis on datasets with millions of co-varying time series. Mapping metadata onto force-directed graphs derived from FASTLSA allows investigators to view correlated cliques and explore previously unrecognized network relationships. The software is freely available for download at: http://www.cmde.science.ubc.ca/hallam/fastLSA/.

  4. Expanding the boundaries of local similarity analysis

    Directory of Open Access Journals (Sweden)

    Durno W Evan

    2013-01-01

    Full Text Available Abstract Background Pairwise comparison of time series data for both local and time-lagged relationships is a computationally challenging problem relevant to many fields of inquiry. The Local Similarity Analysis (LSA statistic identifies the existence of local and lagged relationships, but determining significance through a p-value has been algorithmically cumbersome due to an intensive permutation test, shuffling rows and columns and repeatedly calculating the statistic. Furthermore, this p-value is calculated with the assumption of normality -- a statistical luxury dissociated from most real world datasets. Results To improve the performance of LSA on big datasets, an asymptotic upper bound on the p-value calculation was derived without the assumption of normality. This change in the bound calculation markedly improved computational speed from O(pm2n to O(m2n, where p is the number of permutations in a permutation test, m is the number of time series, and n is the length of each time series. The bounding process is implemented as a computationally efficient software package, FASTLSA, written in C and optimized for threading on multi-core computers, improving its practical computation time. We computationally compare our approach to previous implementations of LSA, demonstrate broad applicability by analyzing time series data from public health, microbial ecology, and social media, and visualize resulting networks using the Cytoscape software. Conclusions The FASTLSA software package expands the boundaries of LSA allowing analysis on datasets with millions of co-varying time series. Mapping metadata onto force-directed graphs derived from FASTLSA allows investigators to view correlated cliques and explore previously unrecognized network relationships. The software is freely available for download at: http://www.cmde.science.ubc.ca/hallam/fastLSA/.

  5. Asteroid clusters similar to asteroid pairs

    Science.gov (United States)

    Pravec, P.; Fatka, P.; Vokrouhlický, D.; Scheeres, D. J.; Kušnirák, P.; Hornoch, K.; Galád, A.; Vraštil, J.; Pray, D. P.; Krugly, Yu. N.; Gaftonyuk, N. M.; Inasaridze, R. Ya.; Ayvazian, V. R.; Kvaratskhelia, O. I.; Zhuzhunadze, V. T.; Husárik, M.; Cooney, W. R.; Gross, J.; Terrell, D.; Világi, J.; Kornoš, L.; Gajdoš, Š.; Burkhonov, O.; Ehgamberdiev, Sh. A.; Donchev, Z.; Borisov, G.; Bonev, T.; Rumyantsev, V. V.; Molotov, I. E.

    2018-04-01

    We studied the membership, size ratio and rotational properties of 13 asteroid clusters consisting of between 3 and 19 known members that are on similar heliocentric orbits. By backward integrations of their orbits, we confirmed their cluster membership and estimated times elapsed since separation of the secondaries (the smaller cluster members) from the primary (i.e., cluster age) that are between 105 and a few 106 years. We ran photometric observations for all the cluster primaries and a sample of secondaries and we derived their accurate absolute magnitudes and rotation periods. We found that 11 of the 13 clusters follow the same trend of primary rotation period vs mass ratio as asteroid pairs that was revealed by Pravec et al. (2010). We generalized the model of the post-fission system for asteroid pairs by Pravec et al. (2010) to a system of N components formed by rotational fission and we found excellent agreement between the data for the 11 asteroid clusters and the prediction from the theory of their formation by rotational fission. The two exceptions are the high-mass ratio (q > 0.7) clusters of (18777) Hobson and (22280) Mandragora for which a different formation mechanism is needed. Two candidate mechanisms for formation of more than one secondary by rotational fission were published: the secondary fission process proposed by Jacobson and Scheeres (2011) and a cratering collision event onto a nearly critically rotating primary proposed by Vokrouhlický et al. (2017). It will have to be revealed from future studies which of the clusters were formed by one or the other process. To that point, we found certain further interesting properties and features of the asteroid clusters that place constraints on the theories of their formation, among them the most intriguing being the possibility of a cascade disruption for some of the clusters.

  6. Industrial technique

    International Nuclear Information System (INIS)

    Nolan, J.H.; Goddard, D.L.; Short, B.J.

    1977-01-01

    An illustrative embodiment of the invention provides pressure relief valve means for the core support cylinder of a nuclear reactor vessel during a failure or accident of the nuclear reactor system. The valve means is responsive to differential pressure across the valve which in one direction sealably seats the valve plate against the valve body, and which, in the other direction opens the valve for pressure relief of the cylinder. Moreover, the valve means is provided with energy absorbing means which limit the impact load of an ''explosively'' opening valve on the reactor vessel wall. 6 claims, 4 figures

  7. Towards novel organic high-Tc superconductors: Data mining using density of states similarity search

    Science.gov (United States)

    Geilhufe, R. Matthias; Borysov, Stanislav S.; Kalpakchi, Dmytro; Balatsky, Alexander V.

    2018-02-01

    Identifying novel functional materials with desired key properties is an important part of bridging the gap between fundamental research and technological advancement. In this context, high-throughput calculations combined with data-mining techniques highly accelerated this process in different areas of research during the past years. The strength of a data-driven approach for materials prediction lies in narrowing down the search space of thousands of materials to a subset of prospective candidates. Recently, the open-access organic materials database OMDB was released providing electronic structure data for thousands of previously synthesized three-dimensional organic crystals. Based on the OMDB, we report about the implementation of a novel density of states similarity search tool which is capable of retrieving materials with similar density of states to a reference material. The tool is based on the approximate nearest neighbor algorithm as implemented in the ANNOY library and can be applied via the OMDB web interface. The approach presented here is wide ranging and can be applied to various problems where the density of states is responsible for certain key properties of a material. As the first application, we report about materials exhibiting electronic structure similarities to the aromatic hydrocarbon p-terphenyl which was recently discussed as a potential organic high-temperature superconductor exhibiting a transition temperature in the order of 120 K under strong potassium doping. Although the mechanism driving the remarkable transition temperature remains under debate, we argue that the density of states, reflecting the electronic structure of a material, might serve as a crucial ingredient for the observed high Tc. To provide candidates which might exhibit comparable properties, we present 15 purely organic materials with similar features to p-terphenyl within the electronic structure, which also tend to have structural similarities with p

  8. Merchandising Techniques and Libraries.

    Science.gov (United States)

    Green, Sylvie A.

    1981-01-01

    Proposes that libraries employ modern booksellers' merchandising techniques to improve circulation of library materials. Using displays in various ways, the methods and reasons for weeding out books, replacing worn book jackets, and selecting new books are discussed. Suggestions for learning how to market and 11 references are provided. (RBF)

  9. Classifying variability modeling techniques

    NARCIS (Netherlands)

    Sinnema, Marco; Deelstra, Sybren

    Variability modeling is important for managing variability in software product families, especially during product derivation. In the past few years, several variability modeling techniques have been developed, each using its own concepts to model the variability provided by a product family. The

  10. A Survey of Cache Bypassing Techniques

    Directory of Open Access Journals (Sweden)

    Sparsh Mittal

    2016-04-01

    Full Text Available With increasing core-count, the cache demand of modern processors has also increased. However, due to strict area/power budgets and presence of poor data-locality workloads, blindly scaling cache capacity is both infeasible and ineffective. Cache bypassing is a promising technique to increase effective cache capacity without incurring power/area costs of a larger sized cache. However, injudicious use of cache bypassing can lead to bandwidth congestion and increased miss-rate and hence, intelligent techniques are required to harness its full potential. This paper presents a survey of cache bypassing techniques for CPUs, GPUs and CPU-GPU heterogeneous systems, and for caches designed with SRAM, non-volatile memory (NVM and die-stacked DRAM. By classifying the techniques based on key parameters, it underscores their differences and similarities. We hope that this paper will provide insights into cache bypassing techniques and associated tradeoffs and will be useful for computer architects, system designers and other researchers.

  11. Industrial technique

    International Nuclear Information System (INIS)

    Jabsen, F.S.

    1978-01-01

    An illustrative embodiment of the invention provides a control rod system locking device adapted to engage an elongated extension shaft, releasably coupled at one end to the control rod assembly and releasably coupled at its other end to the control rod drive, to prevent rotation of the shaft about its longitudinal axis with respect to the control rod assembly

  12. EDITORIAL: Imaging systems and techniques Imaging systems and techniques

    Science.gov (United States)

    Yang, Wuqiang; Giakos, George; Nikita, Konstantina; Pastorino, Matteo; Karras, Dimitrios

    2009-10-01

    and nano-clinics for optical diagnostics and targeted therapy, can play an important role in the diagnosis and treatment of cancer. These techniques can also be used to provide efficient drug delivery for treatment of other diseases, with increased sensitivity and specificity. Similarly, enhanced stand-off detection, classification, identification and surveillance techniques, for comprehensive civilian and military target protection and enhanced space situational awareness can open new frontiers of research and applications in the defence arena and homeland security. For instance, the development of potential imaging sensor architectures, enhanced remote sensing systems, ladars, lidars and radars can provide data capable of ensuring continuous monitoring of various imaging/physical/chemical parameters under different operating conditions, using both active and passive detection principles, reconfigurable and scalable focal plane array architectures, reliable systems for stand-off detection of explosives, and enhanced airport security. The above areas pose challenging problems to the technical community and indicate an ever-growing need for innovative and auspicious solutions. We would like to thank all authors for their valuable contributions, without which this special issue would not have become reality.

  13. #nowplaying Madonna: a large-scale evaluation on estimating similarities between music artists and between movies from microblogs.

    Science.gov (United States)

    Schedl, Markus

    2012-01-01

    Different term weighting techniques such as [Formula: see text] or BM25 have been used intensely for manifold text-based information retrieval tasks. Their use for modeling term profiles for named entities and subsequent calculation of similarities between these named entities have been studied to a much smaller extent. The recent trend of microblogging made available massive amounts of information about almost every topic around the world. Therefore, microblogs represent a valuable source for text-based named entity modeling. In this paper, we present a systematic and comprehensive evaluation of different term weighting measures , normalization techniques , query schemes , index term sets , and similarity functions for the task of inferring similarities between named entities, based on data extracted from microblog posts . We analyze several thousand combinations of choices for the above mentioned dimensions, which influence the similarity calculation process, and we investigate in which way they impact the quality of the similarity estimates. Evaluation is performed using three real-world data sets: two collections of microblogs related to music artists and one related to movies. For the music collections, we present results of genre classification experiments using as benchmark genre information from allmusic.com. For the movie collection, we present results of multi-class classification experiments using as benchmark categories from IMDb. We show that microblogs can indeed be exploited to model named entity similarity with remarkable accuracy, provided the correct settings for the analyzed aspects are used. We further compare the results to those obtained when using Web pages as data source.

  14. Chinese-character crowding-I. Effects of structural similarity.

    Science.gov (United States)

    Cheung, Leo Yuk Ting; Cheung, Sing-Hang

    2017-09-01

    Crowding impedes the identification of flanked objects in peripheral vision. Prior studies have shown crowding strength decreases with target-flanker similarity. Research on crowding in Chinese-character recognition has been scarce in the literature. We aimed to fill the research gap by examining the effects of structural similarity on Chinese-character crowding. Regularity in within-character configuration, i.e., orthographic legality, of flankers was manipulated in Experiment 1. Target-flanker similarity in orthographic legality did not affect crowding strength, measured as contrast threshold elevation. Crowding weakened only when the strokes in the flankers were scrambled. Contour integrity of flankers was manipulated by randomly perturbing the phase spectra of the stimulus images in Experiments 2a and 2b. Crowding by perturbed-phase flankers remained robust but was weaker compared with intact-phase flankers. Target-flanker similarity in contour integrity modulated crowding strength. Our findings were consistent with the postulation that faulty integration of low-level visual features contributed to crowding of Chinese characters. Studies on Chinese-character recognition and crowding can provide important insights into how the visual system processes complex daily objects.

  15. Long-term oil contamination causes similar changes in microbial communities of two distinct soils.

    Science.gov (United States)

    Liao, Jingqiu; Wang, Jie; Jiang, Dalin; Wang, Michael Cai; Huang, Yi

    2015-12-01

    Since total petroleum hydrocarbons (TPH) are toxic and persistent in environments, studying the impact of oil contamination on microbial communities in different soils is vital to oil production engineering, effective soil management and pollution control. This study analyzed the impact of oil contamination on the structure, activity and function in carbon metabolism of microbial communities of Chernozem soil from Daqing oil field and Cinnamon soil from Huabei oil field through both culture-dependent techniques and a culture-independent technique-pyrosequencing. Results revealed that pristine microbial communities in these two soils presented disparate patterns, where Cinnamon soil showed higher abundance of alkane, (polycyclic aromatic hydrocarbons) PAHs and TPH degraders, number of cultivable microbes, bacterial richness, bacterial biodiversity, and stronger microbial activity and function in carbon metabolism than Chernozem soil. It suggested that complicated properties of microbes and soils resulted in the difference in soil microbial patterns. However, the changes of microbial communities caused by oil contamination were similar in respect of two dominant phenomena. Firstly, the microbial community structures were greatly changed, with higher abundance, higher bacterial biodiversity, occurrence of Candidate_division_BRC1 and TAO6, disappearance of BD1-5 and Candidate_division_OD1, dominance of Streptomyces, higher percentage of hydrocarbon-degrading groups, and lower percentage of nitrogen-transforming groups. Secondly, microbial activity and function in carbon metabolism were significantly enhanced. Based on the characteristics of microbial communities in the two soils, appropriate strategy for in situ bioremediation was provided for each oil field. This research underscored the usefulness of combination of culture-dependent techniques and next-generation sequencing techniques both to unravel the microbial patterns and understand the ecological impact of

  16. Providing value in ambulatory anesthesia.

    Science.gov (United States)

    Fosnot, Caroline D; Fleisher, Lee A; Keogh, John

    2015-12-01

    colonoscopies. With this projected increase in the demand for anesthesia services nationwide comes the analysis of its financial feasibility. Some early data looking at endoscopist-administered sedation conclude that it offers higher patient satisfaction, there were less adverse effects than anesthesiologist-administered sedation, and is economically advantageous. This and future retrospective studies will help to guide healthcare policymakers and physicians to come to a conclusion about providing ambulatory services for these millions of patients. Ambulatory anesthesia's popularity continues to rise and anesthetic techniques will continue to morph and adapt to the needs of patients seeking ambulatory surgery. Alterations in already existing medications are promising as these modifications allow for quicker recovery from anesthesia or minimization of the already known undesirable side-effects. PONV, pain, obstructive sleep apnea, and chronic comorbidities (hypertension, cardiac disease, and diabetes mellitus) are perioperative concerns in ambulatory settings as more patients are safely being treated in ambulatory settings. Regional anesthesia stands out as a modality that has multiple advantages to general anesthesia, providing a minimal recovery period and a decrease in postanesthesia care unit stay. The implementation of the Affordable Healthcare Act specifically affects ambulatory settings as the demand and need for patients to have screening procedures with anesthesia. The question remains what the best strategy is to meet the needs of our future patients while preserving economically feasibility within an already strained healthcare system.

  17. Bilateral Waveform Similarity Overlap-and-Add Based Packet Loss Concealment for Voice over IP

    Directory of Open Access Journals (Sweden)

    J.F. Yeh

    2013-08-01

    Full Text Available This paper invested a bilateral waveform similarity overlap-and-add algorithm for voice packet lost. Since Packet lost will cause the semantic misunderstanding, it has become one of the most essential problems in speech communication. This investment is based on waveform similarity measure using overlap-and-Add algorithm and provides the bilateral information to enhance the speech signal reconstruction. Traditionally, it has been improved that waveform similarity overlap-and-add (WSOLA technique is an effective algorithm to deal with packet loss concealment (PLC for real-time time communication. WSOLA algorithm is widely applied to deal with the length adaptation and packet loss concealment of speech signal. Time scale modification of audio signal is one of the most essential research topics in data communication, especially in voice of IP (VoIP. Herein, the proposed the bilateral WSOLA (BWSOLA that is derived from WSOLA. Instead of only exploitation one direction speech data, the proposed method will reconstruct the lost voice data according to the preceding and cascading data. The related algorithms have been developed to achieve the optimal reconstructing estimation. The experimental results show that the quality of the reconstructed speech signal of the bilateral WSOLA is much better compared to the standard WSOLA and GWSOLA on different packet loss rate and length using the metrics PESQ and MOS. The significant improvement is obtained by bilateral information and proposed method. The proposed bilateral waveform similarity overlap-and-add (BWSOLA outperforms the traditional approaches especially in the long duration data loss.

  18. ClusTrack: feature extraction and similarity measures for clustering of genome-wide data sets.

    Directory of Open Access Journals (Sweden)

    Halfdan Rydbeck

    Full Text Available Clustering is a popular technique for explorative analysis of data, as it can reveal subgroupings and similarities between data in an unsupervised manner. While clustering is routinely applied to gene expression data, there is a lack of appropriate general methodology for clustering of sequence-level genomic and epigenomic data, e.g. ChIP-based data. We here introduce a general methodology for clustering data sets of coordinates relative to a genome assembly, i.e. genomic tracks. By defining appropriate feature extraction approaches and similarity measures, we allow biologically meaningful clustering to be performed for genomic tracks using standard clustering algorithms. An implementation of the methodology is provided through a tool, ClusTrack, which allows fine-tuned clustering analyses to be specified through a web-based interface. We apply our methods to the clustering of occupancy of the H3K4me1 histone modification in samples from a range of different cell types. The majority of samples form meaningful subclusters, confirming that the definitions of features and similarity capture biological, rather than technical, variation between the genomic tracks. Input data and results are available, and can be reproduced, through a Galaxy Pages document at http://hyperbrowser.uio.no/hb/u/hb-superuser/p/clustrack. The clustering functionality is available as a Galaxy tool, under the menu option "Specialized analyzis of tracks", and the submenu option "Cluster tracks based on genome level similarity", at the Genomic HyperBrowser server: http://hyperbrowser.uio.no/hb/.

  19. CELL FORMATION IN GROUP TECHNOLOGY: A SIMILARITY ORDER CLUSTERING APPROACH

    Directory of Open Access Journals (Sweden)

    Godfrey C. Onwubolu

    2012-01-01

    Full Text Available Grouping parts into families which can be produced by a cluster of machine cells is the cornerstone of cellular manufacturing, which in turn is the building block for flexible manufacturing systems. Cellular manufacturing is a group technology (GT concept that has recently attracted the attention of manufacturing firms operating under jobshop environment to consider redesigning their manufacturing systems so as to take advantage of increased throughput, reduction in work-in-progress, set-up time, and lead times; leading to product quality and customer satisfaction. The paper presents a generalised approach for machine cell formation from a jobshop using similarity order clustering technique for preliminary cell grouping and considering machine utilisation for the design of nonintergrouping material handling using the single-pass heuristic. The work addresses the shortcomings of cellular manufacturing systems design and implementations which ignore machine utilisations, group sizes and intergroup moves.

  20. Self-similarity of contact line depinning from textured surfaces.

    Science.gov (United States)

    Paxson, Adam T; Varanasi, Kripa K

    2013-01-01

    The mobility of drops on surfaces is important in many biological and industrial processes, but the phenomena governing their adhesion, which is dictated by the morphology of the three-phase contact line, remain unclear. Here we describe a technique for measuring the dynamic behaviour of the three-phase contact line at micron length scales using environmental scanning electron microscopy. We examine a superhydrophobic surface on which a drop's adhesion is governed by capillary bridges at the receding contact line. We measure the microscale receding contact angle of each bridge and show that the Gibbs criterion is satisfied at the microscale. We reveal a hitherto unknown self-similar depinning mechanism that shows how some hierarchical textures such as lotus leaves lead to reduced pinning, and counter-intuitively, how some lead to increased pinning. We develop a model to predict adhesion force and experimentally verify the model's broad applicability on both synthetic and natural textured surfaces.

  1. Similar Symmetries: The Role of Wallpaper Groups in Perceptual Texture Similarity

    Directory of Open Access Journals (Sweden)

    Fraser Halley

    2011-05-01

    Full Text Available Periodic patterns and symmetries are striking visual properties that have been used decoratively around the world throughout human history. Periodic patterns can be mathematically classified into one of 17 different Wallpaper groups, and while computational models have been developed which can extract an image's symmetry group, very little work has been done on how humans perceive these patterns. This study presents the results from a grouping experiment using stimuli from the different wallpaper groups. We find that while different images from the same wallpaper group are perceived as similar to one another, not all groups have the same degree of self-similarity. The similarity relationships between wallpaper groups appear to be dominated by rotations.

  2. Similarity, agreement, and assumed similarity in proxy end-of-life decision making.

    Science.gov (United States)

    McDade-Montez, Elizabeth; Watson, David; Beer, Andrew

    2013-12-01

    Medical decisions near the end of life are often made by proxies who can be inaccurate in their judgments of patient preferences. Given that accuracy in surrogate decision making is an important goal in end-of-life decision making, and in light of that previously seen levels of accuracy reflect substantial disagreement, error, or both, this study examined both relationship and individual factors that potentially affect surrogate accuracy. Specifically, this study examined similarity, agreement, and assumed similarity-a process whereby raters use their own traits and preferences to rate another person-in spousal ratings of end-of-life treatment. This study expands on previous research by examining the potential influence of relationship factors and assumed similarity on end-of-life decision making among a sample of newlyweds. Newly married couples (n = 197) completed self and spouse measures of hypothetical end-of-life preferences and scales assessing marital satisfaction, personality, and attitudes. Results indicate a moderate level of similarity on husband and wife self-rated end-of-life treatment preferences (rs = .18-.29) and a moderate level of agreement between self and proxy ratings (rs = .17-.41). The largest correlations were seen between self ratings and proxy ratings (e.g., husband self ratings and husband proxy ratings of wife preferences, rs = .46-.69), reflecting strong assumed similarity in proxy ratings. For wives, similarity with husbands on a few attitudinal variables (i.e., spirituality, moral strictness, and conservatism) influenced proxy accuracy. Recognizing the potential impact of personal preferences on proxy ratings, as well as the potential influence of relationship factors, may help improve proxy accuracy and end-of-life care for patients and families.

  3. Environmental standards provide competitive advantage

    International Nuclear Information System (INIS)

    Chynoweth, E.; Kirshner, E.

    1993-01-01

    Quality organizations are breaking new ground with the development of international standards for environmental management. These promise to provide the platform for chemical companies wanting to establish their environmental credibility with a global audience. open-quotes It will be similar to auditing our customers to ISO 9000 close-quote, says the environmental manager for a European chemical firm. open-quote We will only want to deal with people who have got their environmental act together. And we'll be in a better competitive positions close-quote. The International Organization for Standardization (ISO;Geneva) has set up a taskforce to develop an environmental management standard, which is expected to be completed by the mid-1990s. Observers think the ISO standard will draw heavily on the British Standard Institute's (BSI;London) environmental management standard, BS7750, which will likely be the first system adopted in the world. Published last year, BS7750 has been extensively piloted in the UK (CW, Sept. 30, 1992, p. 62) and is now set to be revised before being offically adopted by BSI. The UK's Chemical Industries Association (CIA;London) is anxious to prevent a proliferation of standards, and its report on BS7750 pilot projects calls for an approach integrating quality, environment, and health and safety. But standard setters, including ISO, appear to be moving in the opposite direction. In the US, the American national Standards Institute (ANSI;Washington) has started work on an environmental management standard

  4. Similarity and self-similarity in high energy density physics: application to laboratory astrophysics

    International Nuclear Information System (INIS)

    Falize, E.

    2008-10-01

    The spectacular recent development of powerful facilities allows the astrophysical community to explore, in laboratory, astrophysical phenomena where radiation and matter are strongly coupled. The titles of the nine chapters of the thesis are: from high energy density physics to laboratory astrophysics; Lie groups, invariance and self-similarity; scaling laws and similarity properties in High-Energy-Density physics; the Burgan-Feix-Munier transformation; dynamics of polytropic gases; stationary radiating shocks and the POLAR project; structure, dynamics and stability of optically thin fluids; from young star jets to laboratory jets; modelling and experiences for laboratory jets

  5. What Can we Learn from Similar Male Dominated Industries? (Poster Presentation)

    International Nuclear Information System (INIS)

    Thomas, C.; Guilloton, E.

    2015-01-01

    Thomas Thor Associates is an Executive Recruitment company solely dedicated to the Nuclear industry. We have been involved with WiN UK in 2014–2015 to help them develop their own organization, this research was part of our partnership. The main purpose of this paper is to provide a clear picture of the techniques that are used by organizations similar to WiN, and business in other industries that are similar to Nuclear, to attract more women to pursue a career in a particular industry, and to support retention and career progression of women in these industries. This paper has taken a look at all industries that require technical and engineering staff, after which the Mining, Oil & Gas, Petro-chemicals, Rail, Renewable Energy, Technology and Construction industries were found to show most similarities with Nuclear, in terms of the technical staff required and their structure on gender diversity. From here, case studies of industry organizations and professional business have been prepared in order to inform WiN of best practice in these industries and provide a benchmark for future WiN operations. Finally, the report results into giving recommendations on projects WiN could add to their current approach to achieve their objectives. The recommendations are based on the results from the case studies, focusing on attracting, recruiting, retaining and developing female professionals. In summary, the recommendations are to: highlight potential career paths for women in Nuclear, educate women on Nuclear, support the development of women and to help companies to increase their bottom line by getting WiN certified. (author)

  6. Simulation and similarity using models to understand the world

    CERN Document Server

    Weisberg, Michael

    2013-01-01

    In the 1950s, John Reber convinced many Californians that the best way to solve the state's water shortage problem was to dam up the San Francisco Bay. Against massive political pressure, Reber's opponents persuaded lawmakers that doing so would lead to disaster. They did this not by empirical measurement alone, but also through the construction of a model. Simulation and Similarity explains why this was a good strategy while simultaneously providing an account of modeling and idealization in modern scientific practice. Michael Weisberg focuses on concrete, mathematical, and computational models in his consideration of the nature of models, the practice of modeling, and nature of the relationship between models and real-world phenomena. In addition to a careful analysis of physical, computational, and mathematical models, Simulation and Similarity offers a novel account of the model/world relationship. Breaking with the dominant tradition, which favors the analysis of this relation through logical notions suc...

  7. Buckling-driven self-assembly of self-similar inspired micro/nanofibers for ultra-stretchable electronics.

    Science.gov (United States)

    Bian, Jing; Ding, Yajiang; Duan, Yongqing; Wan, Xiaodong; Huang, YongAn

    2017-10-18

    Self-similar structures are capable of highly enhancing the deformability of stretchable electronics. We presented a self-assembly method based on the tunable buckling of serpentine fiber-based interconnects (FiberBIs), which are deposited using our presented helix electrohydrodynamic printing (HE-printing) technique, to fabricate self-similar structures with enhanced stretchability (up to 250%). It provides a low-cost, printing-based approach for the generation of large-scale self-similar FiberBIs. Distinct buckling behaviors and modes occur under specific conditions. To elucidate the mechanics governing this phenomenon, we present detailed experimental and theoretical studies of the buckling mechanics of serpentine microfibers on compliant substrates. Firstly, the effect of the magnitude and direction of prestrain on the buckling behavior of a fiber-on-substrate is discussed. Secondly, the critical geometry of a serpentine fiber as a key parameter for fabricating uniform self-similar fibers is also figured out. Finally, the cross-sectional geometry of the fiber as a judgment criterion for determining the in-surface or out-of-surface buckling of the fiber is established. The investigation can guide the fabrication process of large-scale self-similar structures for high-performance electronic devices with extreme stretchability.

  8. Wireless communications algorithmic techniques

    CERN Document Server

    Vitetta, Giorgio; Colavolpe, Giulio; Pancaldi, Fabrizio; Martin, Philippa A

    2013-01-01

    This book introduces the theoretical elements at the basis of various classes of algorithms commonly employed in the physical layer (and, in part, in MAC layer) of wireless communications systems. It focuses on single user systems, so ignoring multiple access techniques. Moreover, emphasis is put on single-input single-output (SISO) systems, although some relevant topics about multiple-input multiple-output (MIMO) systems are also illustrated.Comprehensive wireless specific guide to algorithmic techniquesProvides a detailed analysis of channel equalization and channel coding for wi

  9. Modern recording techniques

    CERN Document Server

    Huber, David Miles

    2013-01-01

    As the most popular and authoritative guide to recording Modern Recording Techniques provides everything you need to master the tools and day to day practice of music recording and production. From room acoustics and running a session to mic placement and designing a studio Modern Recording Techniques will give you a really good grounding in the theory and industry practice. Expanded to include the latest digital audio technology the 7th edition now includes sections on podcasting, new surround sound formats and HD and audio.If you are just starting out or looking for a step up

  10. Neutron visual sensing technique

    International Nuclear Information System (INIS)

    Kureta, Masatoshi; Segawa, Mariko

    2014-01-01

    The neutron visual sensing technique is a technology to extract physical quantities from the information on inner structures of complex materials or machineries which have been visualized and recorded by using neutron beams. Research and utilization of this technique is now under worldwide development since it can provide the information that is not possible by X-ray radiography. We show how to use stationary neutron sources (Research reactors) in chapter 2, and how to utilize pulsed neutron source (Japan Proton Accelerator Complex, J-PARC). Also the production of micro-element analyzer by an enterprise using the knowledge on radiological equipment is described as an example. (author)

  11. Surface science techniques

    CERN Document Server

    Walls, JM

    2013-01-01

    This volume provides a comprehensive and up to the minute review of the techniques used to determine the nature and composition of surfaces. Originally published as a special issue of the Pergamon journal Vacuum, it comprises a carefully edited collection of chapters written by specialists in each of the techniques and includes coverage of the electron and ion spectroscopies, as well as the atom-imaging methods such as the atom probe field ion microscope and the scanning tunnelling microscope. Surface science is an important area of study since the outermost surface layers play a crucial role

  12. Nonenhanced MR angiography techniques

    International Nuclear Information System (INIS)

    Lanzman, R.S.; Kroepil, P.; Blondin, D.; Schmitt, P.

    2011-01-01

    Especially in regard to the potential risks for the development of nephrogenic systemic fibrosis (NSF) following the administration of Gadolinium-based contrast material, nonenhanced MR angiography (MRA) methods are becoming ever more important. Besides well-established time-of-flight (TOF) and phase-contrast (PC) MRA, alternative imaging techniques based on balanced steady-state free precession (bSSFP) and turbo-spin-echo (TSE) sequences are increasingly used in combination with or without arterial spin labeling (ASL) strategies. This article provides an overview of the principles and clinical values of different nonenhanced MRA techniques. In addition, recent nonenhanced MRA developments are presented. (orig.)

  13. Inhaler technique

    DEFF Research Database (Denmark)

    Levy, M L; Dekhuijzen, P R N; Barnes, P J

    2016-01-01

    of these ideas and to provide new, updated evidence on which to base relevant, meaningful advice in the future. The discussion on each item is followed by a formal, expert opinion by members of the ADMIT Working Group. © 2016 Primary Care Respiratory Society UK/Macmillan Publishers Limited....... to each other and thence to patients. The exercise is intended as a pragmatic, evidence-informed review by a group of clinicians with appropriate experience. It is not intended to be an exhaustive review of the literature; rather, we aim to stimulate debate, and to encourage researchers to challenge some...

  14. SIMILARITIES AND DIFFERENCES BETWEEN MANAGEMENT AND LEADERSHIP

    Directory of Open Access Journals (Sweden)

    VIRGIL POPOVICI

    2012-06-01

    Full Text Available Management is the process of setting and achieving organizational goals through its functions: forecasting, organization, coordination, training and monitoring-evaluation.Leadership is: the ability to influence, to make others follow you, the ability to guide, the human side of business for "teacher". Interest in leadership increased during the early part of the twentieth century. Early leadership theories focused on what qualities distinguished between leaders and followers, while subsequent theories looked at other variables such as situational factors and skill levels.Other considerations emphasize aspects that separate management of leadership, calling them twocompletely different processes.The words manager and lider are very often used to designate the same person who leads, however, they represent different realities and the main difference arises form the way in which people around are motivated.The difference between being a manager and being a leader is simple. Management is a career. Leadership is a calling. A leader is someone who people naturally follow through their own choice, whereas a manager must be obeyed. A manager may only have obtained his position of authority through time and loyalty given to the company, not as a result of his leadership qualities. A leader may have no organisational skills, but his vision unites people behind him.Leadership and management are two notions that are often used interchangeably. However, these words actually describe two different concepts.Leadership is the main component of change, providing vision, and dedication necessary for its realization. Leadership is a skill that is formed by education, experiences, interaction with people and inspiring, of course, practice. Effective leadership depends largely on how their leaders define, follow and share the vision to followers.Leadership is just one important component of the directing function. A manager cannot just be a leader, he also needs

  15. When high similarity copycats lose and moderate similarity copycats gain : The impact of comparative evaluation

    NARCIS (Netherlands)

    van Horen, F.; Pieters, R.

    2012-01-01

    Copycats imitate features of leading brands to free ride on their equity. The prevailing belief is that the more similar copycats are to the leader brand, the more positive their evaluation is, and thus the more they free ride. Three studies demonstrate when the reverse holds true:

  16. Compression for Similarity Identification: Computing the Error Exponent.

    Science.gov (United States)

    Ingber, Amir; Weissman, Tsachy

    2015-04-01

    We consider the problem of compressing discrete memoryless data sequences for the purpose of similarity identification, first studied by Ahlswede et al. (1997). In this setting, a source sequence is compressed, where the goal is to be able to identify whether the original source sequence is similar to another given sequence (called the query sequence). There is no requirement that the source will be reproducible from the compressed version. In the case where no false negatives are allowed, a compression scheme is said to be reliable if the probability of error (false positive) vanishes as the sequence length grows. The minimal compression rate in this sense, which is the parallel of the classical rate distortion function, is called the identification rate . The rate at which the error probability vanishes is measured by its exponent, called the identification exponent (which is the analog of the classical excess distortion exponent). While an information-theoretic expression for the identification exponent was found in past work, it is uncomputable due to a dependency on an auxiliary random variable with unbounded cardinality. The main result of this paper is a cardinality bound on the auxiliary random variable in the identification exponent, thereby making the quantity computable (solving the problem that was left open by Ahlswede et al.). The new proof technique relies on the fact that the Lagrangian in the optimization problem (in the expression for the exponent) can be decomposed by coordinate (of the auxiliary random variable). Then a standard Carathéodory - style argument completes the proof.

  17. Vertical-axis wind turbine experiments at full dynamic similarity

    Science.gov (United States)

    Duvvuri, Subrahmanyam; Miller, Mark; Brownstein, Ian; Dabiri, John; Hultmark, Marcus

    2017-11-01

    This study presents results from pressurized (upto 200 atm) wind tunnel tests of a self-spinning 5-blade model Vertical-Axis Wind Turbine (VAWT). The model is geometrically similar (scale ratio 1:22) to a commercially available VAWT, which has a rotor diameter of 2.17 meters and blade span of 3.66 meters, and is used at the Stanford university field lab. The use of pressurized air as working fluid allows for the unique ability to obtain full dynamic similarity with field conditions in terms of matched Reynolds numbers (Re), tip-speed ratios (λ), and Mach number (M). Tests were performed across a wide range of Re and λ, with the highest Re exceeding the maximum operational field Reynolds number (Remax) by a factor of 3. With an extended range of accessible Re conditions, the peak turbine power efficiency was seen to occur roughly at Re = 2 Remax and λ = 1 . Beyond Re > 2 Remax the turbine performance is invariant in Re for all λ. A clear demonstration of Reynolds number invariance for an actual full-scale wind turbine lends novelty to this study, and overall the results show the viability of the present experimental technique in testing turbines at field conditions.

  18. Multiple-instance learning with pairwise instance similarity

    Directory of Open Access Journals (Sweden)

    Yuan Liming

    2014-09-01

    Full Text Available Multiple-Instance Learning (MIL has attracted much attention of the machine learning community in recent years and many real-world applications have been successfully formulated as MIL problems. Over the past few years, several Instance Selection-based MIL (ISMIL algorithms have been presented by using the concept of the embedding space. Although they delivered very promising performance, they often require long computation times for instance selection, leading to a low efficiency of the whole learning process. In this paper, we propose a simple and efficient ISMIL algorithm based on the similarity of pairwise instances within a bag. The basic idea is selecting from every training bag a pair of the most similar instances as instance prototypes and then mapping training bags into the embedding space that is constructed from all the instance prototypes. Thus, the MIL problem can be solved with the standard supervised learning techniques, such as support vector machines. Experiments show that the proposed algorithm is more efficient than its competitors and highly comparable with them in terms of classification accuracy. Moreover, the testing of noise sensitivity demonstrates that our MIL algorithm is very robust to labeling noise

  19. CLUSS: Clustering of protein sequences based on a new similarity measure

    Directory of Open Access Journals (Sweden)

    Brzezinski Ryszard

    2007-08-01

    Full Text Available Abstract Background The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies of evolutionarily related sequences. This identification reveals phylogenetic relationships, which provide prior knowledge to help researchers understand biological phenomena. A good evolutionary model is essential to achieve a clustering that reflects the biological reality, and an accurate estimate of protein sequence similarity is crucial to the building of such a model. Most existing algorithms estimate this similarity using techniques that are not necessarily biologically plausible, especially for hard-to-align sequences such as proteins with different domain structures, which cause many difficulties for the alignment-dependent algorithms. In this paper, we propose a novel similarity measure based on matching amino acid subsequences. This measure, named SMS for Substitution Matching Similarity, is especially designed for application to non-aligned protein sequences. It allows us to develop a new alignment-free algorithm, named CLUSS, for clustering protein families. To the best of our knowledge, this is the first alignment-free algorithm for clustering protein sequences. Unlike other clustering algorithms, CLUSS is effective on both alignable and non-alignable protein families. In the rest of the paper, we use the term "phylogenetic" in the sense of "relatedness of biological functions". Results To show the effectiveness of CLUSS, we performed an extensive clustering on COG database. To demonstrate its ability to deal with hard-to-align sequences, we tested it on the GH2 family. In addition, we carried out experimental comparisons of CLUSS with a variety of mainstream algorithms. These comparisons were made on hard-to-align and easy-to-align protein sequences. The results of these experiments show the superiority of CLUSS in yielding clusters of proteins

  20. Similarity of TIMSS Math and Science Achievement of Nations

    Directory of Open Access Journals (Sweden)

    Algirdas Zabulionis

    2001-09-01

    Full Text Available In 1991-97, the International Association for the Evaluation of Educational Achievement (IEA undertook a Third International Mathematics and Science Study (TIMSS in which data about the mathematics and science achievement of the thirteen year-old students in more than 40 countries were collected. These data provided the opportunity to search for patterns of students' answers to the test items: which group of items was relatively more difficult (or more easy for the students from a particular country (or group of countries. Using this massive data set an attempt was made to measure the similarities among country profiles of how students responded to the test items.

  1. COUNTRY IMAGE VS. COUNTRY BRAND: DIFFERENCES AND SIMILARITIES

    Directory of Open Access Journals (Sweden)

    Denisa Adriana COTÎRLEA

    2015-08-01

    Full Text Available This article was written in order to provide an overview regarding the differences and similarities regarding two congruent, yet different concepts: country brand and country image. The geopolitical context and, implicitly, the current global context require a redefinition – or a more complex circumscription – of the “country image” and “country branding” concepts. In this paper, the author aimed to highlight the characteristics and particularities of the approached concepts in order to shape a framework of the context within these two operate; a brief analysis of the literature is presented, trying to emphasize the slight difference between the approached concepts

  2. Semantic similarity-based alignment between clinical archetypes and SNOMED CT: an application to observations.

    Science.gov (United States)

    Meizoso García, María; Iglesias Allones, José Luis; Martínez Hernández, Diego; Taboada Iglesias, María Jesús

    2012-08-01

    One of the main challenges of eHealth is semantic interoperability of health systems. But, this will only be possible if the capture, representation and access of patient data is standardized. Clinical data models, such as OpenEHR Archetypes, define data structures that are agreed by experts to ensure the accuracy of health information. In addition, they provide an option to normalize clinical data by means of binding terms used in the model definition to standard medical vocabularies. Nevertheless, the effort needed to establish the association between archetype terms and standard terminology concepts is considerable. Therefore, the purpose of this study is to provide an automated approach to bind OpenEHR archetypes terms to the external terminology SNOMED CT, with the capability to do it at a semantic level. This research uses lexical techniques and external terminological tools in combination with context-based techniques, which use information about structural and semantic proximity to identify similarities between terms and so, to find alignments between them. The proposed approach exploits both the structural context of archetypes and the terminology context, in which concepts are logically defined through the relationships (hierarchical and definitional) to other concepts. A set of 25 OBSERVATION archetypes with 477 bound terms was used to test the method. Of these, 342 terms (74.6%) were linked with 96.1% precision, 71.7% recall and 1.23 SNOMED CT concepts on average for each mapping. It has been detected that about one third of the archetype clinical information is grouped logically. Context-based techniques take advantage of this to increase the recall and to validate a 30.4% of the bindings produced by lexical techniques. This research shows that it is possible to automatically map archetype terms to a standard terminology with a high precision and recall, with the help of appropriate contextual and semantic information of both models. Moreover, the

  3. Relaxation Techniques for Trauma.

    Science.gov (United States)

    Scotland-Coogan, Diane; Davis, Erin

    2016-01-01

    Physiological symptoms of posttraumatic stress disorder (PTSD) manifest as increased arousal and reactivity seen as anger outburst, irritability, reckless behavior with no concern for consequences, hypervigilance, sleep disturbance, and problems with focus (American Psychiatric Association, 2013 ). In seeking the most beneficial treatment for PTSD, consideration must be given to the anxiety response. Relaxation techniques are shown to help address the physiological manifestations of prolonged stress. The techniques addressed by the authors in this article include mindfulness, deep breathing, yoga, and meditation. By utilizing these techniques traditional therapies can be complemented. In addition, those who are averse to the traditional evidence-based practices or for those who have tried traditional therapies without success; these alternative interventions may assist in lessening physiological manifestations of PTSD. Future research studies assessing the benefits of these treatment modalities are warranted to provide empirical evidence to support the efficacy of these treatments.

  4. Deep learning and shapes similarity for joint segmentation and tracing single neurons in SEM images

    Science.gov (United States)

    Rao, Qiang; Xiao, Chi; Han, Hua; Chen, Xi; Shen, Lijun; Xie, Qiwei

    2017-02-01

    Extracting the structure of single neurons is critical for understanding how they function within the neural circuits. Recent developments in microscopy techniques, and the widely recognized need for openness and standardization provide a community resource for automated reconstruction of dendritic and axonal morphology of single neurons. In order to look into the fine structure of neurons, we use the Automated Tape-collecting Ultra Microtome Scanning Electron Microscopy (ATUM-SEM) to get images sequence of serial sections of animal brain tissue that densely packed with neurons. Different from other neuron reconstruction method, we propose a method that enhances the SEM images by detecting the neuronal membranes with deep convolutional neural network (DCNN) and segments single neurons by active contour with group shape similarity. We joint the segmentation and tracing together and they interact with each other by alternate iteration that tracing aids the selection of candidate region patch for active contour segmentation while the segmentation provides the neuron geometrical features which improve the robustness of tracing. The tracing model mainly relies on the neuron geometrical features and is updated after neuron being segmented on the every next section. Our method enables the reconstruction of neurons of the drosophila mushroom body which is cut to serial sections and imaged under SEM. Our method provides an elementary step for the whole reconstruction of neuronal networks.

  5. Computational technique for stepwise quantitative assessment of equation correctness

    Science.gov (United States)

    Othman, Nuru'l Izzah; Bakar, Zainab Abu

    2017-04-01

    Many of the computer-aided mathematics assessment systems that are available today possess the capability to implement stepwise correctness checking of a working scheme for solving equations. The computational technique for assessing the correctness of each response in the scheme mainly involves checking the mathematical equivalence and providing qualitative feedback. This paper presents a technique, known as the Stepwise Correctness Checking and Scoring (SCCS) technique that checks the correctness of each equation in terms of structural equivalence and provides quantitative feedback. The technique, which is based on the Multiset framework, adapts certain techniques from textual information retrieval involving tokenization, document modelling and similarity evaluation. The performance of the SCCS technique was tested using worked solutions on solving linear algebraic equations in one variable. 350 working schemes comprising of 1385 responses were collected using a marking engine prototype, which has been developed based on the technique. The results show that both the automated analytical scores and the automated overall scores generated by the marking engine exhibit high percent agreement, high correlation and high degree of agreement with manual scores with small average absolute and mixed errors.

  6. Similarity of trajectories taking into account geographic context

    Directory of Open Access Journals (Sweden)

    Maike Buchin

    2014-12-01

    Full Text Available The movements of animals, people, and vehicles are embedded in a geographic context. This context influences the movement and may cause the formation of certain behavioral responses. Thus, it is essential to include context parameters in the study of movement and the development of movement pattern analytics. Advances in sensor technologies and positioning devices provide valuable data not only of moving agents but also of the circumstances embedding the movement in space and time. Developing knowledge discovery methods to investigate the relation between movement and its surrounding context is a major challenge in movement analysis today. In this paper we show how to integrate geographic context into the similarity analysis of movement data. For this, we discuss models for geographic context of movement data. Based on this we develop simple but efficient context-aware similarity measures for movement trajectories, which combine a spatial and a contextual distance. These are based on well-known similarity measures for trajectories, such as the Hausdorff, Fréchet, or equal time distance. We validate our approach by applying these measures to movement data of hurricanes and albatross.

  7. Similar or different? The role of the ventrolateral prefrontal cortex in similarity detection.

    Directory of Open Access Journals (Sweden)

    Béatrice Garcin

    Full Text Available Patients with frontal lobe syndrome can exhibit two types of abnormal behaviour when asked to place a banana and an orange in a single category: some patients categorize them at a concrete level (e.g., "both have peel", while others continue to look for differences between these objects (e.g., "one is yellow, the other is orange". These observations raise the question of whether abstraction and similarity detection are distinct processes involved in abstract categorization, and that depend on separate areas of the prefrontal cortex (PFC. We designed an original experimental paradigm for a functional magnetic resonance imaging (fMRI study involving healthy subjects, confirming the existence of two distinct processes relying on different prefrontal areas, and thus explaining the behavioural dissociation in frontal lesion patients. We showed that: 1 Similarity detection involves the anterior ventrolateral PFC bilaterally with a right-left asymmetry: the right anterior ventrolateral PFC is only engaged in detecting physical similarities; 2 Abstraction per se activates the left dorsolateral PFC.

  8. Logistics Service Provider Selection through an Integrated Fuzzy Multicriteria Decision Making Approach

    Directory of Open Access Journals (Sweden)

    Gülşen Akman

    2014-01-01

    Full Text Available Nowadays, the demand of third-party logistics provider becomes an increasingly important issue for companies to improve their customer service and to decrease logistics costs. This paper presents an integrated fuzzy approach for the evaluation and selection of 3rd party logistics service providers. This method consists of two techniques: (1 use fuzzy analytic hierarchy process to identify weights of evaluation criteria; (2 apply fuzzy technique for order preference by similarity to ideal solution (TOPSIS method to evaluate and sequence alternatives and to make the final selection. Finally, an actual industrial application is performed in logistics department of a tire manufacturing company. For this, first, eight logistics supplier selection criteria were determined, and then the best alternative among seven logistics service provider companies was selected by the proposed method.

  9. Niche similarities among introduced and native mountain ungulates.

    Science.gov (United States)

    Lowrey, B; Garrott, R A; McWhirter, D E; White, P J; DeCesare, N J; Stewart, S T

    2018-03-24

    The niche concept provides a strong foundation for theoretical and applied research among a broad range of disciplines. When two ecologically similar species are sympatric, theory predicts they will occupy distinct ecological niches to reduce competition. Capitalizing on the increasing availability of spatial data, we built from single species habitat suitability models to a multispecies evaluation of the niche partitioning hypothesis with sympatric mountain ungulates - native bighorn sheep (BHS; Ovis canadensis) and introduced mountain goats (MTG; Oreamnos americanus) in the northeast Greater Yellowstone Area. We characterized seasonal niches using two-stage resource selection functions with a used-available design and descriptive summaries of the niche attributes associated with used GPS locations. We evaluated seasonal similarity in niche space according to confidence interval overlap of model coefficients and similarity in geographic space by comparing model predicted values with Schoener's D metric. Our sample contained 37,962 summer locations from 53 individuals (BHS = 31, MTG = 22), and 79,984 winter locations from 57 individuals (BHS = 35, MTG = 22). Slope was the most influential niche component for both species and seasons, and showed the strongest evidence of niche partitioning. Bighorn sheep occurred on steeper slopes than mountain goats in summer and mountain goats occurred on steeper slopes in winter. The pattern of differential selection among species was less prevalent for the remaining covariates, indicating similarity in niche space. Model predictions in geographic space showed broad seasonal similarity (summer D = 0.88, winter D = 0.87), as did niche characterizations from used GPS locations. The striking similarities in seasonal niches suggest that introduced mountain goats will continue to increase their spatial overlap with native bighorn. Our results suggest that reducing densities of mountain goats in hunted areas where they are sympatric

  10. Perception of timbre and rhythm similarity in electronic dance music

    NARCIS (Netherlands)

    Honingh, A.; Panteli, M.; Brockmeier, T.; López Mejía, D.I.; Sadakata, M.

    2015-01-01

    Music similarity is known to be a multi-dimensional concept, depending among others on rhythm similarity and timbre similarity. The present study aims to investigate whether such sub-dimensions of similarity can be assessed independently and how they relate to general similarity. To this end, we

  11. Spatiao – Temporal Evaluation and Comparison of MM5 Model using Similarity Algorithm

    Directory of Open Access Journals (Sweden)

    N. Siabi

    2016-02-01

    Full Text Available Introduction temporal and spatial change of meteorological and environmental variables is very important. These changes can be predicted by numerical prediction models over time and in different locations and can be provided as spatial zoning maps with interpolation methods such as geostatistics (16, 6. But these maps are comparable to each other as visual, qualitative and univariate for a limited number of maps (15. To resolve this problem the similarity algorithm is used. This algorithm is a simultaneous comparison method to a large number of data (18. Numerical prediction models such as MM5 were used in different studies (10, 22, and 23. But a little research is done to compare the spatio-temporal similarity of the models with real data quantitatively. The purpose of this paper is to integrate geostatistical techniques with similarity algorithm to study the spatial and temporal MM5 model predicted results with real data. Materials and Methods The study area is north east of Iran. 55 to 61 degrees of longitude and latitude is 30 to 38 degrees. Monthly and annual temperature and precipitation actual data for the period of 1990-2010 was received from the Meteorological Agency and Department of Energy. MM5 Model Data, with a spatial resolution 0.5 × 0.5 degree were downloaded from the NASA website (5. GS+ and ArcGis software were used to produce each variable map. We used multivariate methods co-kriging and kriging with an external drift by applying topography and height as a secondary variable via implementing Digital Elevation Model. (6,12,14. Then the standardize and similarity algorithms (9,11 was applied by programming in MATLAB software to each map grid point. The spatial and temporal similarities between data collections and model results were obtained by F values. These values are between 0 and 0.5 where the value below 0.2 indicates good similarity and above 0.5 shows very poor similarity. The results were plotted on maps by MATLAB

  12. GENERALIZED PROCESSOR SHARING (GPS) TECHNIQUES

    African Journals Online (AJOL)

    Olumide

    popular technique, Generalized Processor Sharing (GPS), provided an effective and efficient utilization of the available resources at the face of stringent and varied QoS requirements. This paper, therefore, presents the comparison of two GPS techniques –. PGPS and CDGPS – based on performance with limited resources ...

  13. Software Testing Techniques and Strategies

    OpenAIRE

    Isha,; Sunita Sangwan

    2014-01-01

    Software testing provides a means to reduce errors, cut maintenance and overall software costs. Numerous software development and testing methodologies, tools, and techniques have emerged over the last few decades promising to enhance software quality. This paper describes Software testing, need for software testing, Software testing goals and principles. Further it describe about different Software testing techniques and different software testing strategies.

  14. Nuclear techniques in agriculture

    International Nuclear Information System (INIS)

    Bhagwat, S.G.

    2012-01-01

    Crops provide us food grains and many other products. Demand for food and other agricultural products is increasing. There is also need for improvement of quality of the agricultural produce. There are several technologies in use for achieving the goal of increasing the quantity and quality of agricultural produce. Nuclear techniques provide us with an option which has certain advantages. The characteristics of crop plants are determined by the genetic make up of the plant. Traditionally the genetic make up was modified using conventional breeding techniques such as cross breeding to improve crops for yield, disease resistance, stress tolerance, resistance to insect pests or to improve quality. New varieties of crops are produced which replace the earlier ones and thus the demands are met. The process of development of new varieties is long and time consuming. Nuclear technique called mutation breeding provides an efficient way of breeding new varieties or improving the older ones. This technique merely enhances the process of occurrence of mutations. In nature mutations occur at a rate of approximately one in a million, while when mutations are induced using radiations such as gamma rays the efficiency of inducing mutations is enhanced. Useful mutations are selected, the mutants are evaluated and developed as a new variety. In the Nuclear Agriculture and Biotechnology Division (NA and BTD) this technique has been used to develop mutants of many crop plants. The mutants can be used to develop a variety directly or by using it in further breeding programme. Using these approaches the NA and BTD has developed 40 new varieties of crops such as groundnut, mungbean, urid, pigeon pea, mustard, soybean, sunflower, cowpea, jute. These varieties are developed in collaboration with other agricultural institutions and are popular among the farming community. The method of mutation breeding can be applied to many other crops for improvement. There is increasing interest among

  15. Theorists and Techniques: Connecting Education Theories to Lamaze Teaching Techniques.

    Science.gov (United States)

    Podgurski, Mary Jo

    2016-01-01

    Should childbirth educators connect education theory to technique? Is there more to learning about theorists than memorizing facts for an assessment? Are childbirth educators uniquely poised to glean wisdom from theorists and enhance their classes with interactive techniques inspiring participant knowledge and empowerment? Yes, yes, and yes. This article will explore how an awareness of education theory can enhance retention of material through interactive learning techniques. Lamaze International childbirth classes already prepare participants for the childbearing year by using positive group dynamics; theory will empower childbirth educators to address education through well-studied avenues. Childbirth educators can provide evidence-based learning techniques in their classes and create true behavioral change.

  16. Prioritization of candidate disease genes by combining topological similarity and semantic similarity.

    Science.gov (United States)

    Liu, Bin; Jin, Min; Zeng, Pan

    2015-10-01

    The identification of gene-phenotype relationships is very important for the treatment of human diseases. Studies have shown that genes causing the same or similar phenotypes tend to interact with each other in a protein-protein interaction (PPI) network. Thus, many identification methods based on the PPI network model have achieved good results. However, in the PPI network, some interactions between the proteins encoded by candidate gene and the proteins encoded by known disease genes are very weak. Therefore, some studies have combined the PPI network with other genomic information and reported good predictive performances. However, we believe that the results could be further improved. In this paper, we propose a new method that uses the semantic similarity between the candidate gene and known disease genes to set the initial probability vector of a random walk with a restart algorithm in a human PPI network. The effectiveness of our method was demonstrated by leave-one-out cross-validation, and the experimental results indicated that our method outperformed other methods. Additionally, our method can predict new causative genes of multifactor diseases, including Parkinson's disease, breast cancer and obesity. The top predictions were good and consistent with the findings in the literature, which further illustrates the effectiveness of our method. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Pollinators show flower colour preferences but flowers with similar colours do not attract similar pollinators.

    Science.gov (United States)

    Reverté, Sara; Retana, Javier; Gómez, José M; Bosch, Jordi

    2016-08-01

    Colour is one of the main floral traits used by pollinators to locate flowers. Although pollinators show innate colour preferences, the view that the colour of a flower may be considered an important predictor of its main pollinators is highly controversial because flower choice is highly context-dependent, and initial innate preferences may be overridden by subsequent associative learning. Our objective is to establish whether there is a relationship between flower colour and pollinator composition in natural communities. We measured the flower reflectance spectrum and pollinator composition in four plant communities (85 plant species represented by 109 populations, and 32 305 plant-pollinator interactions in total). Pollinators were divided into six taxonomic groups: bees, ants, wasps, coleopterans, dipterans and lepidopterans. We found consistent associations between pollinator groups and certain colours. These associations matched innate preferences experimentally established for several pollinators and predictions of the pollination syndrome theory. However, flowers with similar colours did not attract similar pollinator assemblages. The explanation for this paradoxical result is that most flower species are pollination generalists. We conclude that although pollinator colour preferences seem to condition plant-pollinator interactions, the selective force behind these preferences has not been strong enough to mediate the appearance and maintenance of tight colour-based plant-pollinator associations. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Vector similarity measures of hesitant fuzzy linguistic term sets and their applications.

    Science.gov (United States)

    Song, Yongming; Hu, Jun

    2017-01-01

    In decision making, similarity measure and distance between two objects are crucial to be able to determine the relationship between those objects. Many researchers have received much attention for their research on this subject. In this study, we propose two novel similarity measures between hesitant fuzzy linguistic term sets (HFLTSs). In addition, two extensions of Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) are proposed in the hesitant fuzzy linguistic environments. Furthermore, an example of an application concerning traditional Chinese medical diagnosis and an MCDM problem have been given to illustrate the applicability and validation of these similarity measures of HFLTSs. Furthermore, the results of examples demonstrate that the Dice and Jaccard similarity measures are more reasonable than the cosine similarity measure with respect to HFLTSs.

  19. [Psychoanalysis and psychoanalytic oriented psychotherapy: differences and similarities].

    Science.gov (United States)

    Rössler-Schülein, Hemma; Löffler-Stastka, Henriette

    2013-01-01

    Psychoanalysis as well as Psychoanalytic Psychotherapy derived from Psychoanalysis are efficient methods offered by the Austrian health care system in the treatment for anxiety, depression, personality disorders, neurotic and somatoform disorders. In both methods similar basic treatment techniques are applied. Therefore differentiation between both treatment options often is made pragmatically by the frequency of sessions or the use of the couch and seems to be vague in the light of empirical studies. This overview focuses a potential differentiation-the objective and subjective dimensions of the indication process. Concerning the latter it is to investigate, if reflective functioning and ego-integration can be enhanced in the patient during the interaction process between patient and psychoanalyst. Empirical data underline the necessity to investigate to which extent externalizing defence processes are used and to integrate such factors into the decision and indication process. Differing treatment aims display another possibility to differentiate psychoanalysis and psychoanalytic psychotherapy. Psychoanalytic psychotherapy aims for example more at circumscribed problem-foci, the capability for self-reflexion is one of the most prominent treatment effects in psychoanalysis that results in on-going symptom reduction and resilience. The most prominent differentiation lies in the utilization of technical neutrality. Within Psychoanalytic Psychotherapy neutrality has sometimes to be suspended in order to stop severe acting out. Empirical evidence is given concerning the differentiation between psychoanalysis and psychoanalytic psychotherapy, that treatment efficacy is not correlated with the duration of the treatment, but with the frequency of sessions. Results give support to the assumption that the dosage of specific and appropriate psychoanalytic techniques facilitates sustained therapeutic change.

  20. Solution of the weighted symmetric similarity transformations based on quaternions

    Science.gov (United States)

    Mercan, H.; Akyilmaz, O.; Aydin, C.

    2017-12-01

    A new method through Gauss-Helmert model of adjustment is presented for the solution of the similarity transformations, either 3D or 2D, in the frame of errors-in-variables (EIV) model. EIV model assumes that all the variables in the mathematical model are contaminated by random errors. Total least squares estimation technique may be used to solve the EIV model. Accounting for the heteroscedastic uncertainty both in the target and the source coordinates, that is the more common and general case in practice, leads to a more realistic estimation of the transformation parameters. The presented algorithm can handle the heteroscedastic transformation problems, i.e., positions of the both target and the source points may have full covariance matrices. Therefore, there is no limitation such as the isotropic or the homogenous accuracy for the reference point coordinates. The developed algorithm takes the advantage of the quaternion definition which uniquely represents a 3D rotation matrix. The transformation parameters: scale, translations, and the quaternion (so that the rotation matrix) along with their covariances, are iteratively estimated with rapid convergence. Moreover, prior least squares (LS) estimation of the unknown transformation parameters is not required to start the iterations. We also show that the developed method can also be used to estimate the 2D similarity transformation parameters by simply treating the problem as a 3D transformation problem with zero (0) values assigned for the z-components of both target and source points. The efficiency of the new algorithm is presented with the numerical examples and comparisons with the results of the previous studies which use the same data set. Simulation experiments for the evaluation and comparison of the proposed and the conventional weighted LS (WLS) method is also presented.

  1. Path Similarity Analysis: A Method for Quantifying Macromolecular Pathways.

    Directory of Open Access Journals (Sweden)

    Sean L Seyler

    2015-10-01

    Full Text Available Diverse classes of proteins function through large-scale conformational changes and various sophisticated computational algorithms have been proposed to enhance sampling of these macromolecular transition paths. Because such paths are curves in a high-dimensional space, it has been difficult to quantitatively compare multiple paths, a necessary prerequisite to, for instance, assess the quality of different algorithms. We introduce a method named Path Similarity Analysis (PSA that enables us to quantify the similarity between two arbitrary paths and extract the atomic-scale determinants responsible for their differences. PSA utilizes the full information available in 3N-dimensional configuration space trajectories by employing the Hausdorff or Fréchet metrics (adopted from computational geometry to quantify the degree of similarity between piecewise-linear curves. It thus completely avoids relying on projections into low dimensional spaces, as used in traditional approaches. To elucidate the principles of PSA, we quantified the effect of path roughness induced by thermal fluctuations using a toy model system. Using, as an example, the closed-to-open transitions of the enzyme adenylate kinase (AdK in its substrate-free form, we compared a range of protein transition path-generating algorithms. Molecular dynamics-based dynamic importance sampling (DIMS MD and targeted MD (TMD and the purely geometric FRODA (Framework Rigidity Optimized Dynamics Algorithm were tested along with seven other methods publicly available on servers, including several based on the popular elastic network model (ENM. PSA with clustering revealed that paths produced by a given method are more similar to each other than to those from another method and, for instance, that the ENM-based methods produced relatively similar paths. PSA applied to ensembles of DIMS MD and FRODA trajectories of the conformational transition of diphtheria toxin, a particularly challenging example

  2. LASSO-ligand activity by surface similarity order: a new tool for ligand based virtual screening.

    Science.gov (United States)

    Reid, Darryl; Sadjad, Bashir S; Zsoldos, Zsolt; Simon, Aniko

    2008-01-01

    Virtual Ligand Screening (VLS) has become an integral part of the drug discovery process for many pharmaceutical companies. Ligand similarity searches provide a very powerful method of screening large databases of ligands to identify possible hits. If these hits belong to new chemotypes the method is deemed even more successful. eHiTS LASSO uses a new interacting surface point types (ISPT) molecular descriptor that is generated from the 3D structure of the ligand, but unlike most 3D descriptors it is conformation independent. Combined with a neural network machine learning technique, LASSO screens molecular databases at an ultra fast speed of 1 million structures in under 1 min on a standard PC. The results obtained from eHiTS LASSO trained on relatively small training sets of just 2, 4 or 8 actives are presented using the diverse directory of useful decoys (DUD) dataset. It is shown that over a wide range of receptor families, eHiTS LASSO is consistently able to enrich screened databases and provides scaffold hopping ability.

  3. LASSO—ligand activity by surface similarity order: a new tool for ligand based virtual screening

    Science.gov (United States)

    Reid, Darryl; Sadjad, Bashir S.; Zsoldos, Zsolt; Simon, Aniko

    2008-06-01

    Virtual Ligand Screening (VLS) has become an integral part of the drug discovery process for many pharmaceutical companies. Ligand similarity searches provide a very powerful method of screening large databases of ligands to identify possible hits. If these hits belong to new chemotypes the method is deemed even more successful. eHiTS LASSO uses a new interacting surface point types (ISPT) molecular descriptor that is generated from the 3D structure of the ligand, but unlike most 3D descriptors it is conformation independent. Combined with a neural network machine learning technique, LASSO screens molecular databases at an ultra fast speed of 1 million structures in under 1 min on a standard PC. The results obtained from eHiTS LASSO trained on relatively small training sets of just 2, 4 or 8 actives are presented using the diverse directory of useful decoys (DUD) dataset. It is shown that over a wide range of receptor families, eHiTS LASSO is consistently able to enrich screened databases and provides scaffold hopping ability.

  4. Prediction of maize hybrid performance using similarity in state and similarity by descent information.

    Science.gov (United States)

    Ferreira, D V; Von Pinho, R G; Balestre, M; Oliveira, R L

    2010-12-14

    We evaluated the efficiency of the best linear unbiased predictor (BLUP) and the influence of the use of similarity in state (SIS) and similarity by descent (SBD) in the prediction of untested maize hybrids. Nine inbred lines of maize were crossed using a randomized complete diallel method. These materials were genotyped with 48 microsatellite markers (SSR) associated with the QTL regions for grain yield. Estimates of four coefficients of SIS and four coefficients of SBD were used to construct the additive genetic and dominance matrices, which were later used in combination with the BLUP for predicting genotypic values and specific combining ability (SCA) in unanalyzed hybrids under simulated unbalance. The values of correlations between the genotypic values predicted and the means observed, depending on the degree of unbalance, ranged from 0.48 to 0.99 for SIS and 0.40 to 0.99 using information from SBD. The results obtained for the SCA ranged from 0.26 to 0.98 using the SIS and 0.001 to 0.990 using the SBD information. It was also observed that the predictions using SBD showed less biased than SIS predictions demonstrating that the predictions obtained by these coefficients (SBD) were closer to the observed value, but were less efficient in the ranking of genotypes. Although the SIS showed a bias due to overestimation of relatedness, this type of coefficient may be used where low values are detected in the SBD in the group of parents because of its greater efficiency in ranking the candidates hybrids.

  5. SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters

    Directory of Open Access Journals (Sweden)

    Lefkowitz Elliot J

    2004-10-01

    Full Text Available Abstract Background Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a useful source of functional and structural information about these sequences. Using software such as the basic local alignment search tool (BLAST or HMMPFAM to identify statistically significant matches between newly sequenced segments of genetic material and those in databases is an important task for most molecular biologists. Searching algorithms are intrinsically slow and data-intensive, especially in light of the rapid growth of biological sequence databases due to the emergence of high throughput DNA sequencing techniques. Thus, traditional bioinformatics tools are impractical on PCs and even on dedicated UNIX servers. To take advantage of larger databases and more reliable methods, high performance computation becomes necessary. Results We describe the implementation of SS-Wrapper (Similarity Search Wrapper, a package of wrapper applications that can parallelize similarity search applications on a Linux cluster. Our wrapper utilizes a query segmentation-search (QS-search approach to parallelize sequence database search applications. It takes into consideration load balancing between each node on the cluster to maximize resource usage. QS-search is designed to wrap many different search tools, such as BLAST and HMMPFAM using the same interface. This implementation does not alter the original program, so newly obtained programs and program updates should be accommodated easily. Benchmark experiments using QS-search to optimize BLAST and HMMPFAM showed that QS-search accelerated the performance of these programs almost linearly in proportion to the number of CPUs used. We have also implemented a wrapper that utilizes a database segmentation approach (DS-BLAST that provides a complementary solution for BLAST searches when the database is too large to fit into

  6. SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters.

    Science.gov (United States)

    Wang, Chunlin; Lefkowitz, Elliot J

    2004-10-28

    Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a useful source of functional and structural information about these sequences. Using software such as the basic local alignment search tool (BLAST) or HMMPFAM to identify statistically significant matches between newly sequenced segments of genetic material and those in databases is an important task for most molecular biologists. Searching algorithms are intrinsically slow and data-intensive, especially in light of the rapid growth of biological sequence databases due to the emergence of high throughput DNA sequencing techniques. Thus, traditional bioinformatics tools are impractical on PCs and even on dedicated UNIX servers. To take advantage of larger databases and more reliable methods, high performance computation becomes necessary. We describe the implementation of SS-Wrapper (Similarity Search Wrapper), a package of wrapper applications that can parallelize similarity search applications on a Linux cluster. Our wrapper utilizes a query segmentation-search (QS-search) approach to parallelize sequence database search applications. It takes into consideration load balancing between each node on the cluster to maximize resource usage. QS-search is designed to wrap many different search tools, such as BLAST and HMMPFAM using the same interface. This implementation does not alter the original program, so newly obtained programs and program updates should be accommodated easily. Benchmark experiments using QS-search to optimize BLAST and HMMPFAM showed that QS-search accelerated the performance of these programs almost linearly in proportion to the number of CPUs used. We have also implemented a wrapper that utilizes a database segmentation approach (DS-BLAST) that provides a complementary solution for BLAST searches when the database is too large to fit into the memory of a single node. Used together

  7. Agricultural production - Phase 2. Indonesia. Rice - azolla - fish culture - use of nuclear technique

    International Nuclear Information System (INIS)

    Watanabe, Iwao.

    1991-01-01

    The primary aim of the expert mission was to provide advice on the use of nuclear techniques to study rice-azolla-fish culture. Results of the work performed so far show that basal application of azolla gives similar or better yields of rice than basal application of urea. Fish productivity was also found to be significantly higher when azolla is present. 2 tabs

  8. Undergraduate Research and a Liberal Arts Education: Similar Goals, Similar Solutions

    Science.gov (United States)

    Kaiser, Bonnie Nicole; Mishler, Dennis M.; Peoples, Whitney A.; Wells, Alexis S.

    2014-01-01

    In this nascent age of massive online education, it is important to recognize that the goals and successes of a liberal arts education have been to provide an intellectual array of ideas that build critical thinking skills and to engage a new generation of students with society's great challenges and vast opportunities. Nowhere are these…

  9. The diversity and similarity of simulated cold dark matter haloes

    Science.gov (United States)

    Navarro, Julio F.; Ludlow, Aaron; Springel, Volker; Wang, Jie; Vogelsberger, Mark; White, Simon D. M.; Jenkins, Adrian; Frenk, Carlos S.; Helmi, Amina

    2010-02-01

    We study the mass, velocity dispersion and anisotropy profiles of Λ cold dark matter (ΛCDM) haloes using a suite of N-body simulations of unprecedented numerical resolution. The Aquarius Project follows the formation of six different galaxy-sized haloes simulated several times at varying numerical resolution, allowing numerical convergence to be assessed directly. The highest resolution simulation represents a single dark matter halo using 4.4 billion particles, of which 1.1 billion end up within the virial radius. Our analysis confirms a number of results claimed by earlier work, and clarifies a few issues where conflicting claims may be found in the recent literature. The mass profile of ΛCDM haloes deviates slightly but systematically from the form proposed by Navarro, Frenk & White. The spherically averaged density profile becomes progressively shallower inwards and, at the innermost resolved radius, the logarithmic slope is γ ≡ - d ln ρ/d ln r universal: different haloes cannot, in general, be rescaled to look identical. Departures from similarity are also seen in velocity dispersion profiles and correlate with those in density profiles so as to preserve a power-law form for the spherically averaged pseudo-phase-space density, ρ/σ3 ~ r-1.875. The index here is identical to that of Bertschinger's similarity solution for self-similar infall on to a point mass from an otherwise uniform Einstein-de Sitter universe. The origin of this striking behaviour is unclear, but its robustness suggests that it reflects a fundamental structural property of ΛCDM haloes. Our conclusions are reliable down to radii below 0.4 per cent of the virial radius, providing well-defined predictions for halo structure when baryonic effects are neglected, and thus an instructive theoretical template against which the modifications induced by the baryonic components of real galaxies can be judged.

  10. Nursing Home Provider Perceptions of Telemedicine for Providing Specialty Consults.

    Science.gov (United States)

    Driessen, Julia; Chang, Woody; Patel, Palak; Wright, Rollin M; Ernst, Kambria; Handler, Steven M

    2018-01-02

    Nursing homes (NHs) provide care to a complex patient population and face the ongoing challenge of meeting resident needs for specialty care. A NH telemedicine care model could improve access to remote specialty providers. Little is known about provider interest in telemedicine for specialty consults in the NH setting. The goal of this study was to survey a national sample of NH physicians and advanced practice providers to document their views on telemedicine for providing specialty consults in the NH. We surveyed physician and advanced practice providers who attended the 2016 AMDA-The Society for Post-Acute and Long-Term Care Medicine Annual Conference about their likelihood of referral to and perceptions of a telemedicine program for providing specialty consults in the NH. We received surveys from 524 of the 1,274 conference attendees for a 41.1% response rate. Respondents expressed confidence in the ability of telemedicine to fill existing service gaps and provide appropriate, timelier care. Providers showed the highest level of interest in telemedicine for dermatology, geriatric psychiatry, and infectious disease. Only 13% of respondents indicated that telemedicine was available for use in one of their facilities. There appears to be unmet demand for telemedicine in NHs for providing specialty consults to residents. The responses of NH providers suggest support for the concept of telemedicine as a modality of care that can be used to offer specialty consults to NH residents.

  11. Tokunaga self-similarity for symmetric homogeneous Markov chains

    Science.gov (United States)

    Kovchegov, Y.; Zaliapin, I.

    2010-12-01

    Hierarchical branching organization is ubiquitous in nature. It is readily seen in river basins, drainage networks, bronchial passages, botanical trees, and snowflakes, to mention but a few. Empirical evidence suggests that one can describe many natural hierarchies by so-called Tokunaga self-similar trees (SSTs) [Shreve, 1969; Tokunaga, 1978; Ossadnik, 1992; Peckham, 1995; Newman et al., 1997; Pelletier and Turcotte, 2000]; Tokunaga SST have been proven to describe the Galton-Watson critical branching [Burd et al., 2000] and a general particle coagulation process [Gabrielov et al., 1999]. Tokunaga SSTs form a special two-parametric class of SSTs that preserves its statistical properties under the operation of pruning, i.e., cutting the leaves. It has been conjectured (Webb and Zaliapin, 2009; Zaliapin et al. 2009) that Tokunaga self-similarity is a characteristic property of the inverse aggregation (coagulation) process. This study provides further evidence in support of this hypothesis by focusing on trees that describe the topological structure of level sets of a time series, so-called level-set trees (LST). We prove that the LST for a symmetric homogeneous Markov chain (HMC) is a Tokunaga SST with the same parameters as the famous Shreve tree and critical Galton-Watson tree. We show, furthermore, that the Tokunaga property holds for any transformation F[X(G(t))] of a symmetric HMC X(t), where F and G are monotone increasing functions, and as a result - for the regular Brownian motion. At the same time, the Tokunaga property does not hold in general in asymmetric HMCs, a Brownian motion with a drift, ARMA, and some other conventional models. We discuss the relation of our results to the Tokunaga self-similarity of the nearest-neighbor trees for random point sets. References: 1. Gabrielov, A., W.I. Newman, D.L. Turcotte (1999) An exactly soluble hierarchical clustering model: inverse cascades, self-similarity, and scaling. Phys. Rev. E, 1999, 60, 5293-5300. 2

  12. Symptom Similarities and Differences in Anxiety and Depressive Disorders

    Directory of Open Access Journals (Sweden)

    Dilek Sirvanli Ozen

    2010-04-01

    Full Text Available The question if there is a valid distinction between depression and anxiety disorders remains controversial. These two disorders have various overlaps in the symptomatology and sometimes it is difficult to make a clear diagnosis. The difficulty in making a definite diagnosis destined researchers to determine the differences and the similarities between anxiety and depression. The negative affect which has multiple dimensions such as low self-esteem, negative mood and negative cognitions is seen as the common factor in both disorders. The positive affect which has been defined as the harmony and satisfaction with others and milieu, is regarded as the discriminating factor for the diagnosis of depression. Further research has characterized somatic arousal as the third dimension, a candidate to be the discriminating factor for anxiety disorders. Although phenotypic models appear to find a solution for this problem the facts that negative affect dimension is more loaded compared to the other two dimensions and predominance of negative affect on several symptom patterns prevent researchers to reach a conclusive results regarding the differences between these two disorders. In this review article, symptom similarities and differences of anxiety and depressive disorders are discussed within the frame of phenotypic models and some alternative ideas are provided for possible changes in upcoming versions of classification systems.

  13. GIS: a comprehensive source for protein structure similarities.

    Science.gov (United States)

    Guerler, Aysam; Knapp, Ernst-Walter

    2010-07-01

    A web service for analysis of protein structures that are sequentially or non-sequentially similar was generated. Recently, the non-sequential structure alignment algorithm GANGSTA+ was introduced. GANGSTA+ can detect non-sequential structural analogs for proteins stated to possess novel folds. Since GANGSTA+ ignores the polypeptide chain connectivity of secondary structure elements (i.e. alpha-helices and beta-strands), it is able to detect structural similarities also between proteins whose sequences were reshuffled during evolution. GANGSTA+ was applied in an all-against-all comparison on the ASTRAL40 database (SCOP version 1.75), which consists of >10,000 protein domains yielding about 55 x 10(6) possible protein structure alignments. Here, we provide the resulting protein structure alignments as a public web-based service, named GANGSTA+ Internet Services (GIS). We also allow to browse the ASTRAL40 database of protein structures with GANGSTA+ relative to an externally given protein structure using different constraints to select specific results. GIS allows us to analyze protein structure families according to the SCOP classification scheme. Additionally, users can upload their own protein structures for pairwise protein structure comparison, alignment against all protein structures of the ASTRAL40 database (SCOP version 1.75) or symmetry analysis. GIS is publicly available at http://agknapp.chemie.fu-berlin.de/gplus.

  14. Currents connecting communities: nearshore community similarity and ocean circulation.

    Science.gov (United States)

    Watson, J R; Hays, C G; Raimondi, P T; Mitarai, S; Dong, C; McWilliams, J C; Blanchette, C A; Caselle, J E; Siegel, D A

    2011-06-01

    Understanding the mechanisms that create spatial heterogeneity in species distributions is fundamental to ecology. For nearshore marine systems, most species have a pelagic larval stage where dispersal is strongly influenced by patterns of ocean circulation. Concomitantly, nearshore habitats and the local environment are also influenced by ocean circulation. Because of the shared dependence on the seascape, distinguishing the relative importance of the local environment from regional patterns of dispersal for community structure remains a challenge. Here, we quantify the "oceanographic distance" and "oceanographic asymmetry" between nearshore sites using ocean circulation modeling results. These novel metrics quantify spatial separation based on realistic patterns of ocean circulation, and we explore their explanatory power for intertidal and subtidal community similarity in the Southern California Bight. We find that these metrics show significant correspondence with patterns of community similarity and that their combined explanatory power exceeds that of the thermal structure of the domain. Our approach identifies the unique influence of ocean circulation on community structure and provides evidence for oceanographically mediated dispersal limitation in nearshore marine communities.

  15. A new similarity measure for complex amplitude holographic data

    Science.gov (United States)

    Ahar, Ayyoub; Birnbaum, Tobias; Jaeh, Christian; Schelkens, Peter

    2017-09-01

    In this research, we have adapted our recently proposed Versatile Similarity Measure (VSM) for holographic data analysis. This new measure benefits from nice mathematical properties like boundedness to [0;1], relative error weighting based on the magnitudes of the signals, steerable similarity between original and negative phase; symmetry with respect to ordering of the arguments and the regularity of at least a continuous function. Utilizing its versatile design, here we present a set of VSM constructions specifically tailored to best fit the characteristics of complex wavefield of holograms. Also performance analysis results are provided by comparing the proposed constructions as fast, stand-alone perceptual quality predictors to few available competitors of the field, namely MSE and the average SSIM of the real and imaginary parts of holograms. Comparing their visual quality prediction scores with the mean opinion scores (MOS) of the hologram reconstructions shows a significant gain for all of the VSM constructions proposed in this paper, paving the way towards designing highly efficient perceptual quality predictors for holographic data in the future and also representing the potential of utilizing VSM for other applications working with complex valued data as well.

  16. Topological similarity of random cell complexes and applications

    Science.gov (United States)

    Schweinhart, B.; Mason, J. K.; MacPherson, R. D.

    2016-06-01

    Although random cell complexes occur throughout the physical sciences, there does not appear to be a standard way to quantify their statistical similarities and differences. The various proposals in the literature are usually motivated by the analysis of particular physical systems and do not necessarily apply to general situations. The central concepts in this paper—the swatch and the cloth—provide a description of the local topology of a cell complex that is general (any physical system that can be represented as a cell complex is admissible) and complete (any statistical question about the local topology can be answered from the cloth). Furthermore, this approach allows a distance to be defined that measures the similarity of the local topology of two cell complexes. The distance is used to identify a steady state of a model grain boundary network, quantify the approach to this steady state, and show that the steady state is independent of the initial conditions. The same distance is then employed to show that the long-term properties in simulations of a specific model of a dislocation network do not depend on the implementation of dislocation intersections.

  17. Resilience and sustainability: Similarities and differences in environmental management applications.

    Science.gov (United States)

    Marchese, Dayton; Reynolds, Erin; Bates, Matthew E; Morgan, Heather; Clark, Susan Spierre; Linkov, Igor

    2018-02-01

    In recent years there have been many disparate uses of the terms sustainability and resilience, with some framing sustainability and resilience as the same concept, and others claiming them to be entirely different and unrelated. To investigate similarities, differences, and current management frameworks for increasing sustainability and resilience, a literature review was undertaken that focused on integrated use of sustainability and resilience in an environmental management context. Sustainability was defined through the triple bottom line of environmental, social and economic system considerations. Resilience was viewed as the ability of a system to prepare for threats, absorb impacts, recover and adapt following persistent stress or a disruptive event. Three generalized management frameworks for organizing sustainability and resilience were found to dominate the literature: (1) resilience as a component of sustainability, (2) sustainability as a component of resilience, and (3) resilience and sustainability as separate objectives. Implementations of these frameworks were found to have common goals of providing benefits to people and the environment under normal and extreme operating conditions, with the best examples building on similarities and minimizing conflicts between resilience and sustainability. Published by Elsevier B.V.

  18. Tokunaga and Horton self-similarity for level set trees of Markov chains

    International Nuclear Information System (INIS)

    Zaliapin, Ilia; Kovchegov, Yevgeniy

    2012-01-01

    Highlights: ► Self-similar properties of the level set trees for Markov chains are studied. ► Tokunaga and Horton self-similarity are established for symmetric Markov chains and regular Brownian motion. ► Strong, distributional self-similarity is established for symmetric Markov chains with exponential jumps. ► It is conjectured that fractional Brownian motions are Tokunaga self-similar. - Abstract: The Horton and Tokunaga branching laws provide a convenient framework for studying self-similarity in random trees. The Horton self-similarity is a weaker property that addresses the principal branching in a tree; it is a counterpart of the power-law size distribution for elements of a branching system. The stronger Tokunaga self-similarity addresses so-called side branching. The Horton and Tokunaga self-similarity have been empirically established in numerous observed and modeled systems, and proven for two paradigmatic models: the critical Galton–Watson branching process with finite progeny and the finite-tree representation of a regular Brownian excursion. This study establishes the Tokunaga and Horton self-similarity for a tree representation of a finite symmetric homogeneous Markov chain. We also extend the concept of Horton and Tokunaga self-similarity to infinite trees and establish self-similarity for an infinite-tree representation of a regular Brownian motion. We conjecture that fractional Brownian motions are also Tokunaga and Horton self-similar, with self-similarity parameters depending on the Hurst exponent.

  19. Similarity Measure for Molecular Structure: A Brief Review

    Science.gov (United States)

    Bero, S. A.; Muda, A. K.; Choo, Y. H.; Muda, N. A.; Pratama, S. F.

    2017-09-01

    Similarity or distance measures have been used widely to calculate the similarity or dissimilarity between two samples of dataset. Cheminformatics is known as the domain that dealing with chemical information and both similarity and distance coefficient have been an important role for matching, searching and classification of chemical information. There are various types of similarity/distance coefficient used in molecular structure similarity searching. Generally, the calculation using similarity/distance coefficient is focusing more on 2-dimensional (2D) rather than 3-dimensional (3D) structure. In this paper, the popular similarity/distance coefficients for molecular structure will be reviewed together with the review on 3D molecular structure.

  20. Truncal blocks for perioperative pain management: a review of the literature and evolving techniques.

    Science.gov (United States)

    Go, Ramon; Huang, Yolanda Y; Weyker, Paul D; Webb, Christopher Aj

    2016-10-01

    As the American healthcare system continues to evolve and reimbursement becomes tied to value-based incentive programs, perioperative pain management will become increasingly important. Regional anesthetic techniques are only one component of a successful multimodal pain regimen. In recent years, the use of peripheral and paraneuraxial blocks to provide chest wall and abdominal analgesia has gained popularity. When used within a multimodal regimen, truncal blocks may provide similar analgesia when compared with other regional anesthetic techniques. While there are other reviews that cover this topic, our review will also highlight the emerging role for serratus plane blocks, pectoral nerve blocks and quadratus lumborum blocks in providing thoracic and abdominal analgesia.

  1. Ultrasonic techniques for fluids characterization

    CERN Document Server

    Povey, Malcolm J W

    1997-01-01

    This book is a comprehensive and practical guide to the use of ultrasonic techniques for the characterization of fluids. Focusing on ultrasonic velocimetry, the author covers the basic topics and techniques necessaryfor successful ultrasound measurements on emulsions, dispersions, multiphase media, and viscoelastic/viscoplastic materials. Advanced techniques such as scattering, particle sizing, and automation are also presented. As a handbook for industrial and scientific use, Ultrasonic Techniques for Fluids Characterization is an indispensable guide to chemists and chemical engineers using ultrasound for research or process monitoring in the chemical, food processing, pharmaceutical, cosmetic, biotechnology,and fuels industries. Key Features * Appeals to anyone using ultrasound to study fluids * Provides the first detailed description of the ultrasound profiling technique for dispersions * Describes new techniques for measuring phase transitions and nucleation, such as water/ice and oil/fat * Presents the l...

  2. Identifying a Superfluid Reynolds Number via Dynamical Similarity.

    Science.gov (United States)

    Reeves, M T; Billam, T P; Anderson, B P; Bradley, A S

    2015-04-17

    The Reynolds number provides a characterization of the transition to turbulent flow, with wide application in classical fluid dynamics. Identifying such a parameter in superfluid systems is challenging due to their fundamentally inviscid nature. Performing a systematic study of superfluid cylinder wakes in two dimensions, we observe dynamical similarity of the frequency of vortex shedding by a cylindrical obstacle. The universality of the turbulent wake dynamics is revealed by expressing shedding frequencies in terms of an appropriately defined superfluid Reynolds number, Re(s), that accounts for the breakdown of superfluid flow through quantum vortex shedding. For large obstacles, the dimensionless shedding frequency exhibits a universal form that is well-fitted by a classical empirical relation. In this regime the transition to turbulence occurs at Re(s)≈0.7, irrespective of obstacle width.

  3. Phytomonas serpens: immunological similarities with the human trypanosomatid pathogens.

    Science.gov (United States)

    Santos, André L S; d'Avila-Levy, Claudia M; Elias, Camila G R; Vermelho, Alane B; Branquinha, Marta H

    2007-07-01

    The present review provides an overview of recent discoveries concerning the immunological similarities between Phytomonas serpens, a tomato parasite, and human trypanosomatid pathogens, with special emphasis on peptidases. Leishmania spp. and Trypanosoma cruzi express peptidases that are well-known virulence factors, named leishmanolysin and cruzipain. P. serpens synthesizes two distinct classes of proteolytic enzymes, metallo- and cysteine-type peptidases, that share common epitopes with leishmanolysin and cruzipain, respectively. The leishmanolysin-like and cruzipain-like molecules from P. serpens participate in several biological processes including cellular growth and adhesion to the salivary glands of Oncopeltus fasciatus, a phytophagous insect experimental model. Since previous reports demonstrated that immunization of mice with P. serpens induced a partial protective immune response against T. cruzi, this plant trypanosomatid may be a suitable candidate for vaccine studies. Moreover, comparative approaches in the Trypanosomatidae family may be useful to understand kinetoplastid biology, biochemistry and evolution.

  4. Self-similar spherical metrics with tangential pressure

    CERN Document Server

    Gair, J R

    2002-01-01

    A family of spherically symmetric spacetimes is discussed, which have anisotropic pressure and possess a homothetic Killing vector. The spacetimes are composed of dust with a tangential pressure provided by angular momentum of the dust particles. The solution is given implicitly by an elliptic integral and depends on four arbitrary functions. These represent the initial configurations of angular momentum, mass, energy and position of the shells. The solution is derived by imposing self-similarity in the coordinates R, the shell label, and tau, the proper time experienced by the dust. Conditions for evolution without shell crossing and a description of singularity formation are given and types of solution discussed. General properties of the solutions are illustrated by reference to a particular case, which represents a universe that exists for an infinite time, but in which every shell expands and recollapses in a finite time.

  5. Signal integrity characterization techniques

    CERN Document Server

    Bogatin, Eric

    2009-01-01

    "Signal Integrity Characterization Techniques" addresses the gap between traditional digital and microwave curricula all while focusing on a practical and intuitive understanding of signal integrity effects within the data transmission channel. High-speed interconnects such as connectors, PCBs, cables, IC packages, and backplanes are critical elements of differential channels that must be designed using today's most powerful analysis and characterization tools.Both measurements and simulation must be done on the device under test, and both activities must yield data that correlates with each other. Most of this book focuses on real-world applications of signal integrity measurements - from backplane for design challenges to error correction techniques to jitter measurement technologies. The authors' approach wisely addresses some of these new high-speed technologies, and it also provides valuable insight into its future direction and will teach the reader valuable lessons on the industry.

  6. [Therapeutic education didactic techniques].

    Science.gov (United States)

    Valverde, Maite; Vidal, Mercè; Jansa, Margarida

    2012-10-01

    This article includes an introduction to the role of Therapeutic Education for Diabetes treatment according to the recommendations of the American Diabetes Association (ADA), the Diabetes Education Study Group (DESG) of the "European Association for Study of Diabetes (EASD) and the clinical Practice Guidelines (CPG) of the Spanish Ministry of Health. We analyze theoretical models and the differences between teaching vs. learning as well as current trends (including Internet), that can facilitate meaningful learning of people with diabetes and their families and relatives. We analyze the differences, similarities, advantages and disadvantages of individual and group education. Finally, we describe different educational techniques (metaplan, case method, brainstorming, role playing, games, seminars, autobiography, forums, chats,..) applicable to individual, group or virtual education and its application depending on the learning objective.

  7. Retinoid-binding proteins: similar protein architectures bind similar ligands via completely different ways.

    Directory of Open Access Journals (Sweden)

    Yu-Ru Zhang

    Full Text Available BACKGROUND: Retinoids are a class of compounds that are chemically related to vitamin A, which is an essential nutrient that plays a key role in vision, cell growth and differentiation. In vivo, retinoids must bind with specific proteins to perform their necessary functions. Plasma retinol-binding protein (RBP and epididymal retinoic acid binding protein (ERABP carry retinoids in bodily fluids, while cellular retinol-binding proteins (CRBPs and cellular retinoic acid-binding proteins (CRABPs carry retinoids within cells. Interestingly, although all of these transport proteins possess similar structures, the modes of binding for the different retinoid ligands with their carrier proteins are different. METHODOLOGY/PRINCIPAL FINDINGS: In this work, we analyzed the various retinoid transport mechanisms using structure and sequence comparisons, binding site analyses and molecular dynamics simulations. Our results show that in the same family of proteins and subcellular location, the orientation of a retinoid molecule within a binding protein is same, whereas when different families of proteins are considered, the orientation of the bound retinoid is completely different. In addition, none of the amino acid residues involved in ligand binding is conserved between the transport proteins. However, for each specific binding protein, the amino acids involved in the ligand binding are conserved. The results of this study allow us to propose a possible transport model for retinoids. CONCLUSIONS/SIGNIFICANCE: Our results reveal the differences in the binding modes between the different retinoid-binding proteins.

  8. Efficient EMD-based Similarity Search in Multimedia Databases via Flexible Dimensionality Reduction

    DEFF Research Database (Denmark)

    Wichterich, Marc; Assent, Ira; Philipp, Kranen

    2008-01-01

    The Earth Mover's Distance (EMD) was developed in computer vision as a flexible similarity model that utilizes similarities in feature space to define a high quality similarity measure in feature representation space. It has been successfully adopted in a multitude of applications with low...... dimensionality reduction techniques for the EMD in a filter-and-refine architecture for efficient lossless retrieval. Thorough experimental evaluation on real world data sets demonstrates a substantial reduction of the number of expensive high-dimensional EMD computations and thus remarkably faster response...

  9. Would it provide Free Education?

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Would it provide Free Education? Would it provide Free Education? Would it provide Compulsory Education? Would it guarantee education of equitable quality? Would it prevent discrimination? Would it stop schools that promote inequality & discrimination? NO! NO!

  10. Icy Islands reveal similar volatile behavior on Pluto and Mars

    Science.gov (United States)

    Sori, M.; Bapst, J.; Byrne, S.

    2017-12-01

    Ice deposits on planetary surfaces may hold paleoclimate records and elucidate important geologic processes involving volatiles, atmospheres, topography, and climate. Sputnik Planitia on Pluto and the well-studied north and south polar layered deposits (NPLD and SPLD) of Mars are examples. Ice peripheral to these main deposits may be even more sensitive to climatic changes. At northern martian latitudes, 18 outlying H2O ice mounds have previously been mapped within impact craters (Fig. 1a) near the NPLD. Here, we use remote sensing observations from New Horizons and Mars orbital spacecraft to study similar features in craters near Sputnik Planitia and the SPLD. We identify tens of outlying topographic mounds in craters near the SPLD (Fig. 1b) and five bright albedo features in craters near Sputnik Planitia (Fig. 1c). We assess the possibility that these deposits are analogous to the H2O ice mounds at northern martian polar latitudes. The southern martian deposits are physically diverse, but always include convex topography and host craters >15 km in diameter. We interpret at least some of them to be composed of H2O ice like their northern counterparts. The five features on Pluto are located in similarly sized craters and have corresponding spectral detections of N2 ice. One (Fig. 1c) has topography very similar to martian ice mounds, including a convex shape up to 160 m thick. We conclude it is an N2 ice mound, equivalent to Mars' H2O ice mounds in that crater topography provides a favorable microclimate for volatiles. The mound may preserve a paleoclimate record that would be erased in Sputnik Planitia by convection. Using a finite element model, we estimate flow velocities of this N2 ice mound to be 1 cm/yr, implying it may be younger than the other four which could have topography subdued by viscous relaxation. We compare the properties and possible formation mechanisms of these features to test the hypothesis that Pluto's ice cycle is similar to Mars' in

  11. Do pastoral care providers recognize nurses as spiritual care providers?

    Science.gov (United States)

    Cavendish, Roberta; Edelman, Maryann; Naradovy, Linda; Bajo, Maryann McPartlan; Perosi, Irene; Lanza, Melissa

    2007-01-01

    This descriptive qualitative study was conducted to explicate pastoral care providers' perceptions of nurses as spiritual providers. Spirituality is especially meaningful in contemporary society as a whole with spiritual care an expectation of hospitalized patients. Spiritual care given by nurses is grounded in nursing's history, inherent in its philosophical framework, and supported by research and professional mandates. In hospitals today, the primary responsibility for the spiritual care of patients resides with pastoral care providers. Collaboration between pastoral care providers and nurses may improve patients' spiritual care outcomes. Before collaboration can occur, it is important to learn whether pastoral care providers recognize nurses as spiritual providers. Guided by qualitative research methods, participants were sought until data saturation occurred. This qualitative study consisted of 8 participants who were experienced, full-time pastoral care providers from general and religious-affiliated hospitals. Data were collected through audiotaped open-ended interviews, a demographic data form, and exploratory questions or probes. The analysis included concurrent data collection, constant examination of conceptual interactions, linkages, and the conditions under which they occurred. Themes emerged: quest, conscious response, and essence of caring. Pastoral care providers perceive nurses as spiritual providers. Few felt comfortable initiating collaboration. Study findings are not generalizable.

  12. Visual Evaluation Techniques for Skill Analysis.

    Science.gov (United States)

    Brown, Eugene W.

    1982-01-01

    Visual evaluation techniques provide the kinesiologist with a method of evaluating physical skill performance. The techniques are divided into five categories: (1) vantage point; (2) movement simplification; (3) balance and stability; (4) movement relationships; and (5) range of movement. (JN)

  13. A Technique: Exposure Therapy

    Directory of Open Access Journals (Sweden)

    Serkan AKKOYUNLU

    2013-07-01

    Full Text Available Introduction: Exposure with response prevention is an effective treatment for all anxiety disorders. According to the behavioral learning theories, fears which are conditioned via classical conditioning are reinforced by respondent conditioning. Avoidance and safety seeking behaviors prevent disconfirmation of anxious beliefs. In exposure client faces stimulates or cues that elicit fear or distress, by this avoidance is inhibited. Clients are also encouraged to resists performing safety seeking behaviors or rituals that they utilize to reduce fear or distress. Accomplishing these habituation or extinction is achieved. In addition to this clients learn that feared consequences does not realize or not harmful as they believed by experiencing. Emotional processing is believed to be the mechanism of change in exposure.Objective: The aim of this review is to provide a definition of exposure and its effectiveness briefly, and describe how to implement exposure, its steps and remarkable aspects using. Exposure therapies and treatments that involve exposure are proved to be effective in all anxiety disorders. Exposure therapy can be divided in three parts: Assessment and providing a treatment rationale, creating an exposure hierarchy and response prevention plan, implementing exposure sessions. Clients must also continue to perform exposure between sessions. Therapy transcripts are also provided to exemplify these parts. Conclusion: Exposure with response prevention is a basic and effective technique. Every cognitive behavior therapist must be able to implement this technique and be cognizant of pearls of this procedure.

  14. On the measurements of molecular similarity: a connection between quantum chemistry and artificial intelligence

    International Nuclear Information System (INIS)

    Carbo, R.; Calabuig, B.

    1988-01-01

    Molecular similarity measures within the quantum concept of density functions are described and analyzed. It is intended to show how artificial intelligence techniques can be used within the framework of quantum theory, in order to study and classify the molecular structures and their properties. (A.C.A.S) [pt

  15. MDP challenges from a software provider's perspective

    Science.gov (United States)

    Ohara, Shuichiro

    2014-10-01

    This industry faces new challenges every day. It gets tougher as process nodes shrink and the data complexity and volume increase. We are a mask data preparation (MDP) software provider, and have been providing MDP systems to mask shops since 1990. As the industry has, MDP software providers also have been facing new challenges over time, and the challenges get tougher as process nodes shrink and the data complexity and volume increase. We discuss such MDP challenges and solutions in this paper from a MDP software provider's perspective. The data volume continuously increases, and it is caused by shrinking the process node. In addition, resolution enhancement techniques (RET) such as optical proximity correction (OPC) and inverse lithography technique (ILT) induce data complexity, and it contributes considerably to the increase in data volume. The growth of data volume and complexity brings challenges to MDP system, such as the computing speed, shot count, and mask process correction (MPC). New tools (especially mask writers) also bring new challenges. Variable-shaped E-beam (VSB) mask writers demand fracturing less slivers and lower figure counts for CD accuracy and write time requirements respectively. Now multibeam mask writers are under development and will definitely bring new challenges.

  16. Epidemiology of Recurrent Acute and Chronic Pancreatitis: Similarities and Differences.

    Science.gov (United States)

    Machicado, Jorge D; Yadav, Dhiraj

    2017-07-01

    Emerging data in the past few years suggest that acute, recurrent acute (RAP), and chronic pancreatitis (CP) represent a disease continuum. This review discusses the similarities and differences in the epidemiology of RAP and CP. RAP is a high-risk group, comprised of individuals at varying risk of progression. The premise is that RAP is an intermediary stage in the pathogenesis of CP, and a subset of RAP patients during their natural course transition to CP. Although many clinical factors have been identified, accurately predicting the probability of disease course in individual patients remains difficult. Future studies should focus on providing more precise estimates of the risk of disease transition in a cohort of patients, quantification of clinical events during the natural course of disease, and discovery of biomarkers of the different stages of the disease continuum. Availability of clinically relevant endpoints and linked biomarkers will allow more accurate prediction of the natural course of disease over intermediate- or long-term-based characteristics of an individual patient. These endpoints will also provide objective measures for use in clinical trials of interventions that aim to alter the natural course of disease.

  17. Communication strategies and accommodations utilized by health care providers with hearing loss: a pilot study.

    Science.gov (United States)

    Trotter, Alanna R; Matt, Susan B; Wojnara, Danuta

    2014-03-01

    Poor communication between health care providers and patients may negatively impact patient outcomes, and enhancing communication is one way to improve outcomes. Effective communication is particularly important for health care providers who have hearing loss. The authors found that a systematic survey of the communication strategies and experiences of health care providers with hearing loss had not yet been conducted. In this pilot study, 32 health care professionals with hearing loss were recruited via the Association of Medical Professionals With Hearing Losses and were asked to complete a 28-question survey. Health care providers with hearing loss already employ strategies that all health care providers are encouraged to use in order to enhance patient–provider communication, and survey participants have found the strategies to be effective. The communication techniques and assistive technologies used by individuals with hearing loss seem to be effective: All participants reported feeling able to communicate effectively with patients at least most of the time. More research is needed to determine if use of these communication techniques has similar results for health care providers without hearing loss.

  18. Similarities between obesity in pets and children: the addiction model.

    Science.gov (United States)

    Pretlow, Robert A; Corbee, Ronald J

    2016-09-01

    Obesity in pets is a frustrating, major health problem. Obesity in human children is similar. Prevailing theories accounting for the rising obesity rates - for example, poor nutrition and sedentary activity - are being challenged. Obesity interventions in both pets and children have produced modest short-term but poor long-term results. New strategies are needed. A novel theory posits that obesity in pets and children is due to 'treats' and excessive meal amounts given by the 'pet-parent' and child-parent to obtain affection from the pet/child, which enables 'eating addiction' in the pet/child and results in parental 'co-dependence'. Pet-parents and child-parents may even become hostage to the treats/food to avoid the ire of the pet/child. Eating addiction in the pet/child also may be brought about by emotional factors such as stress, independent of parental co-dependence. An applicable treatment for child obesity has been trialled using classic addiction withdrawal/abstinence techniques, as well as behavioural addiction methods, with significant results. Both the child and the parent progress through withdrawal from specific 'problem foods', next from snacking (non-specific foods) and finally from excessive portions at meals (gradual reductions). This approach should adapt well for pets and pet-parents. Pet obesity is more 'pure' than child obesity, in that contributing factors and treatment points are essentially under the control of the pet-parent. Pet obesity might thus serve as an ideal test bed for the treatment and prevention of child obesity, with focus primarily on parental behaviours. Sharing information between the fields of pet and child obesity would be mutually beneficial.

  19. Electrocardiogram Signal Quality Assessment Based on Structural Image Similarity Metric.

    Science.gov (United States)

    Shahriari, Yalda; Fidler, Richard; Pelter, Michele M; Bai, Yong; Villaroman, Andrea; Hu, Xiao

    2018-04-01

    We developed an image-based electrocardiographic (ECG) quality assessment technique that mimics how clinicians annotate ECG signal quality. We adopted the structural similarity measure (SSIM) to compare images of two ECG records that are obtained from displaying ECGs in a standard scale. Then, a subset of representative ECG images from the training set was selected as templates through a clustering method. SSIM between each image and all the templates were used as the feature vector for the linear discriminant analysis classifier. We also employed three commonly used ECG signal quality index (SQI) measures: baseSQI, kSQI, and sSQI to compare with the proposed image quality index (IQI) approach. We used 1926 annotated ECGs, recorded from patient monitors, and associated with six different ECG arrhythmia alarm types which were obtained previously from an ECG alarm study at the University of California, San Francisco (UCSF). In addition, we applied the templates from the UCSF database to test the SSIM approach on the publicly available PhysioNet Challenge 2011 data. For the UCSF database, the proposed IQI algorithm achieved an accuracy of 93.1% and outperformed all the SQI metrics, baseSQI, kSQI, and sSQI, with accuracies of 85.7%, 63.7%, and 73.8% respectively. Moreover, evaluation of our algorithm on the PhysioNet data showed an accuracy of 82.5%. The proposed algorithm showed better performance for assessing ECG signal quality than traditional signal processing methods. A more accurate assessment of ECG signal quality can lead to a more robust ECG-based diagnosis of cardiovascular conditions.

  20. Similarity and conditional similarity reductions of a (2+1)-dimensional KdV equation via a direct method

    Science.gov (United States)

    Lou, Sen-yue; Tang, Xiao-yan; Lin, Ji

    2000-12-01

    To get the similarity solutions of a nonlinear physical equation, one may use the classical Lie group approach, nonclassical Lie group approach and the Clarkson and Kruskal (CK) direct method. In this paper the direct method is modified to get the similarity and conditional similarity reductions of a (2+1) dimensional KdV-type equation. Ten types of usual similarity reductions [including the (1+1)-dimensional shallow water wave equation and the variable KdV equation] and six types of conditional similarity reductions of the (2+1)-dimensional KdV equation are obtained. Some special solutions of the conditional similarity reduction equations are found to show the nontriviality of the conditional similarity reduction approach. The conditional similarity solutions cannot be obtained by using the nonclassical Lie group approach in its present form. How to modify the nonclassical Lie group approach to obtain the conditional similarity solutions is still open.

  1. Babesiosis for Health Care Providers

    Centers for Disease Control (CDC) Podcasts

    2012-04-25

    This podcast will educate health care providers on diagnosing babesiosis and providing patients at risk with tick bite prevention messages.  Created: 4/25/2012 by Center for Global Health, Division of Parasitic Diseases and Malaria.   Date Released: 4/25/2012.

  2. Perspectives of addiction treatment providers

    African Journals Online (AJOL)

    Background. General practitioners are referring patients with codeine-related problems to specialist treatment facilities, but little is known about the addiction treatment providers, the kinds of treatment they provide, and whether training or other interventions are needed to strengthen this sector. Objectives. To investigate the ...

  3. How EPA's Asbestos Regulations Apply to Window Caulk, Glazing Compound, Wiring and Other Similar Materials

    Science.gov (United States)

    Letters that provide guidance on asbestos National Emissions Standard of Hazardous Air Pollutants (NESHAP) applicability to linoleum, tar paper, electric wiring, floor tile mastic, caulking compounds, and other similar materials during demolition

  4. Incentives and provider payment methods.

    Science.gov (United States)

    Barnum, H; Kutzin, J; Saxenian, H

    1995-01-01

    The mode of payment creates powerful incentives affecting provider behavior and the efficiency, equity and quality outcomes of health finance reforms. This article examines provider incentives as well as administrative costs, and institutional conditions for successful implementation associated with provider payment alternatives. The alternatives considered are budget reforms, capitation, fee-for-service, and case-based reimbursement. We conclude that competition, whether through a regulated private sector or within a public system, has the potential to improve the performance of any payment method. All methods generate both adverse and beneficial incentives. Systems with mixed forms of provider payment can provide tradeoffs to offset the disadvantages of individual modes. Low-income countries should avoid complex payment systems requiring higher levels of institutional development.

  5. Neurobiological correlates of internet gaming disorder: Similarities to pathological gambling.

    Science.gov (United States)

    Fauth-Bühler, M; Mann, K

    2017-01-01

    The number of massively multiplayer online games (MMOs) is on the rise worldwide along with the fascination that they inspire. Problems occur when the use of MMOs becomes excessive at the expense of other life domains. Although not yet formally included as disorder in common diagnostic systems, internet gaming disorder (IGD) is considered a "condition for further study" in section III of the DSM-5. The current review aims to provide an overview of cognitive and neurobiological data currently available on IGD, with a particular focus on impulsivity, compulsivity, and sensitivity to reward and punishment. Additionally, we also compare these findings on IGD with data from studies on pathological gambling (PG)-so far the only condition officially classified as a behavioral addiction in the DSM-5. Multiple similarities have been observed in the neurobiology of IGD and PG, as measured by alterations in brain function and behavior. Both patients with IGD and those with PG exhibited decreased loss sensitivity; enhanced reactivity to gaming and gambling cues, respectively; enhanced impulsive choice behavior; aberrant reward-based learning; and no changes in cognitive flexibility. In conclusion, the evidence base on the neurobiology of gaming and gambling disorders is beginning to illuminate the similarities between the two. However, as only a few studies have addressed the neurobiological basis of IGD, and some of these studies suffer from significant limitations, more research is required before IGD's inclusion as a second behavioral addiction in the next versions of the ICD and DSM can be justified. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Computer-aided beam arrangement based on similar cases in radiation treatment-planning databases for stereotactic lung radiation therapy

    International Nuclear Information System (INIS)

    Magome, Taiki; Shioyama, Yoshiyuki; Arimura, Hidetaka

    2013-01-01

    The purpose of this study was to develop a computer-aided method for determination of beam arrangements based on similar cases in a radiotherapy treatment-planning database for stereotactic lung radiation therapy. Similar-case-based beam arrangements were automatically determined based on the following two steps. First, the five most similar cases were searched, based on geometrical features related to the location, size and shape of the planning target volume, lung and spinal cord. Second, five beam arrangements of an objective case were automatically determined by registering five similar cases with the objective case, with respect to lung regions, by means of a linear registration technique. For evaluation of the beam arrangements five treatment plans were manually created by applying the beam arrangements determined in the second step to the objective case. The most usable beam arrangement was selected by sorting the five treatment plans based on eight plan evaluation indices, including the D95, mean lung dose and spinal cord maximum dose. We applied the proposed method to 10 test cases, by using an RTP database of 81 cases with lung cancer, and compared the eight plan evaluation indices between the original treatment plan and the corresponding most usable similar-case-based treatment plan. As a result, the proposed method may provide usable beam arrangements, which have no statistically significant differences from the original beam arrangements (P>0.05) in terms of the eight plan evaluation indices. Therefore, the proposed method could be employed as an educational tool for less experienced treatment planners. (author)

  7. Vere-Jones' self-similar branching model

    International Nuclear Information System (INIS)

    Saichev, A.; Sornette, D.

    2005-01-01

    Motivated by its potential application to earthquake statistics as well as for its intrinsic interest in the theory of branching processes, we study the exactly self-similar branching process introduced recently by Vere-Jones. This model extends the ETAS class of conditional self-excited branching point-processes of triggered seismicity by removing the problematic need for a minimum (as well as maximum) earthquake size. To make the theory convergent without the need for the usual ultraviolet and infrared cutoffs, the distribution of magnitudes m ' of daughters of first-generation of a mother of magnitude m has two branches m ' ' >m with exponent β+d, where β and d are two positive parameters. We investigate the condition and nature of the subcritical, critical, and supercritical regime in this and in an extended version interpolating smoothly between several models. We predict that the distribution of magnitudes of events triggered by a mother of magnitude m over all generations has also two branches m ' ' >m with exponent β+h, with h=d√(1-s), where s is the fraction of triggered events. This corresponds to a renormalization of the exponent d into h by the hierarchy of successive generations of triggered events. For a significant part of the parameter space, the distribution of magnitudes over a full catalog summed over an average steady flow of spontaneous sources (immigrants) reproduces the distribution of the spontaneous sources with a single branch and is blind to the exponents β,d of the distribution of triggered events. Since the distribution of earthquake magnitudes is usually obtained with catalogs including many sequences, we conclude that the two branches of the distribution of aftershocks are not directly observable and the model is compatible with real seismic catalogs. In summary, the exactly self-similar Vere-Jones model provides an attractive new approach to model triggered seismicity, which alleviates delicate questions on the role of

  8. Resource use by two morphologically similar insectivorous bats ...

    African Journals Online (AJOL)

    Studies of morphologically dissimilar insectivorous bats have lead to the conclusion that morphology is the prime correlate of habitat use, and consequently of diet. This has lead to the prediction that morphologically similar bats should have similar diets. We examined the diet and morphology of two morphologically similar ...

  9. 7 CFR 51.632 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.632 Section 51.632 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards..., and Arizona) Definitions § 51.632 Similar varietal characteristics. Similar varietal characteristics...

  10. 7 CFR 51.2081 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2081 Section 51.2081 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the almonds are similar in shape, and are reasonably...

  11. 7 CFR 51.3202 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.3202 Section 51.3202 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Similar varietal characteristics. Similar varietal characteristics means that the onions in any container...

  12. 7 CFR 51.567 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.567 Section 51... STANDARDS) United States Standards for Celery Definitions § 51.567 Similar varietal characteristics. Similar varietal characteristics means that the stalks in any package have the same general appearance and...

  13. 7 CFR 51.763 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.763 Section 51.763 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the fruits in any container are similar in color and...

  14. 7 CFR 51.2116 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2116 Section 51.2116 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the kernels are similar in shape and appearance. For...

  15. 7 CFR 51.3057 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.3057 Section 51.3057 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the avocados in any container are similar in shape...

  16. 7 CFR 51.694 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.694 Section 51.694 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards..., and Arizona) Definitions § 51.694 Similar varietal characteristics. Similar varietal characteristics...

  17. 7 CFR 51.2650 - Similar varietal characteristics.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Similar varietal characteristics. 51.2650 Section 51.2650 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... characteristics. Similar varietal characteristics means that the cherries in any container are similar in color...

  18. Towards Modelling Variation in Music as Foundation for Similarity

    NARCIS (Netherlands)

    Volk, A.; de Haas, W.B.; van Kranenburg, P.; Cambouropoulos, E.; Tsougras, C.; Mavromatis, P.; Pastiadis, K.

    2012-01-01

    This paper investigates the concept of variation in music from the perspective of music similarity. Music similarity is a central concept in Music Information Retrieval (MIR), however there exists no comprehensive approach to music similarity yet. As a consequence, MIR faces the challenge on how to

  19. Using Crowdsourcing to Investigate Perception of Narrative Similarity

    NARCIS (Netherlands)

    Nguyen, Dong-Phuong; Trieschnigg, Rudolf Berend; Theune, Mariet

    2014-01-01

    For many applications measuring the similarity between documents is essential. However, little is known about how users perceive similarity between documents. This paper presents the first large-scale empirical study that investigates perception of narrative similarity using crowdsourcing. As a

  20. Similarities in functional attributes and nutritional effects of magadi ...

    African Journals Online (AJOL)

    The similarity in properties especially in mineral profile, alkalinity, decreased cooking time and lowered mineral uptake by magadi soda and bean debris-ash explain similar functionality in foods they are added to during cooking. Despite the similarities observed, communities should be informed of the negative nutritional ...

  1. 29 CFR 4043.68 - Bankruptcy or similar settlement.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Bankruptcy or similar settlement. 4043.68 Section 4043.68... Bankruptcy or similar settlement. (a) Reportable event and information required. Advance notice is required for a bankruptcy or similar settlement, as described in § 4043.35(a), and the notice shall include the...

  2. Assessment of structural similarity in CT using filtered backprojection and iterative reconstruction: a phantom study with 3D printed lung vessels.

    Science.gov (United States)

    Joemai, Raoul M S; Geleijns, Jacob

    2017-11-01

    To compare the performance of three generations of CT reconstruction techniques using structural similarity (SSIM) as a measure of image quality for CT scans of a chest phantom with 3D printed lung vessels. CT images of the chest phantom were acquired at seven dose levels by changing the tube current while other acquisition parameters were kept constant. Three CT reconstruction techniques were applied on each acquisition. The first technique was filtered backprojection (FBP), the second technique was FBP with iterative filtering (adaptive iteration dose reduction in 3 dimensions (AIDR 3D)) and the third technique was model-based iterative reconstruction (Forward projected model-based Iterative Reconstruction SoluTion (FIRST)). Image quality of the CT data was quantified in terms of SSIM. The SSIM index was used for image quality comparison between the dose levels and different reconstruction techniques. The SSIM index gives a value between 0 and 1, with 0 as the lowest image quality and 1 as an excellent image quality. The lowest SSIM index was observed for FBP at all dose levels. The reconstruction technique with the highest SSIM depends on the dose level. For tube currents higher than 80 mA, AIDR 3D showed the highest SSIM index, and for tube currents lower or equal to 80 mA FIRST showed the highest SSIM index. SSIM index is a robust quantity and is correlated to the image quality as perceived by the humans. Advanced CT reconstruction techniques provide better image quality in all conditions compared to FBP. Advances in knowledge: SSIM is a robust measure to compare CT image quality for advanced reconstruction techniques relative to a reference. The 3D print technology is an useful method for the development of dedicated phantoms for CT image quality evaluation.

  3. Similarity solutions for flow of non-Newtonian fluids in porous media revisited under parameter uncertainty

    Science.gov (United States)

    Ciriello, Valentina; Di Federico, Vittorio

    2012-07-01

    We analyze the transient motion of a non-Newtonian power-law fluid in a porous medium of infinite extent and given geometry (plane, cylindrical or spherical). The flow in the domain, initially at constant ambient pressure, is induced by fluid withdrawal or injection in the domain origin at prescribed pressure or injection rate. Previous literature work is generalized and expanded, providing a dimensionless formulation suitable for any geometry, and deriving similarity solutions to the nonlinear governing equations valid for pseudoplastic, Newtonian and dilatant fluids. A pressure front propagating with finite velocity is generated when the fluid is pseudoplastic; no such front exists for Newtonian or dilatant fluids. The front rate of advance depends directly on fluid flow behavior index and inversely on medium porosity and domain dimensionality. The effects and relative importance of uncertain input parameters on the model outputs are investigated via Global Sensitivity Analysis by calculating the Sobol' indices of (a) pressure front position and (b) domain pressure, by adopting the Polynomial Chaos Expansion technique. For the selected case study, the permeability is the most influential factor affecting the system responses.

  4. Short-Term Power Forecasting Model for Photovoltaic Plants Based on Historical Similarity

    Directory of Open Access Journals (Sweden)

    M. Sonia Terreros-Olarte

    2013-05-01

    Full Text Available This paper proposes a new model for short-term forecasting of electric energy production in a photovoltaic (PV plant. The model is called HIstorical SImilar MIning (HISIMI model; its final structure is optimized by using a genetic algorithm, based on data mining techniques applied to historical cases composed by past forecasted values of weather variables, obtained from numerical tools for weather prediction, and by past production of electric power in a PV plant. The HISIMI model is able to supply spot values of power forecasts, and also the uncertainty, or probabilities, associated with those spot values, providing new useful information to users with respect to traditional forecasting models for PV plants. Such probabilities enable analysis and evaluation of risk associated with those spot forecasts, for example, in offers of energy sale for electricity markets. The results of spot forecasting of an illustrative example obtained with the HISIMI model for a real-life grid-connected PV plant, which shows high intra-hour variability of its actual power output, with forecasting horizons covering the following day, have improved those obtained with other two power spot forecasting models, which are a persistence model and an artificial neural network model.

  5. Classification of peacock feather reflectance using principal component analysis similarity factors from multispectral imaging data.

    Science.gov (United States)

    Medina, José M; Díaz, José A; Vukusic, Pete

    2015-04-20

    Iridescent structural colors in biology exhibit sophisticated spatially-varying reflectance properties that depend on both the illumination and viewing angles. The classification of such spectral and spatial information in iridescent structurally colored surfaces is important to elucidate the functional role of irregularity and to improve understanding of color pattern formation at different length scales. In this study, we propose a non-invasive method for the spectral classification of spatial reflectance patterns at the micron scale based on the multispectral imaging technique and the principal component analysis similarity factor (PCASF). We demonstrate the effectiveness of this approach and its component methods by detailing its use in the study of the angle-dependent reflectance properties of Pavo cristatus (the common peacock) feathers, a species of peafowl very well known to exhibit bright and saturated iridescent colors. We show that multispectral reflectance imaging and PCASF approaches can be used as effective tools for spectral recognition of iridescent patterns in the visible spectrum and provide meaningful information for spectral classification of the irregularity of the microstructure in iridescent plumage.

  6. Cunninghamella Biotransformation--Similarities to Human Drug Metabolism and Its Relevance for the Drug Discovery Process.

    Science.gov (United States)

    Piska, Kamil; Żelaszczyk, Dorota; Jamrozik, Marek; Kubowicz-Kwaśny, Paulina; Pękala, Elżbieta

    2016-01-01

    Studies of drug metabolism are one of the most significant issues in the process of drug development, its introduction to the market and also in treatment. Even the most promising molecule may show undesirable metabolic properties that would disqualify it as a potential drug. Therefore, such studies are conducted in the early phases of drug discovery and development process. Cunninghamella is a filamentous fungus known for its catalytic properties, which mimics mammalian drug metabolism. It has been proven that C. elegans carries at least one gene coding for a CYP enzyme closely related to the CYP51 family. The transformation profile of xenobiotics in Cunninghamella spp. spans a number of reactions catalyzed by different mammalian CYP isoforms. This paper presents detailed data on similar biotransformation drug products in humans and Cunninghamella spp. and covers the most important aspects of preparative biosynthesis of metabolites, since this model allows to obtain metabolites in sufficient quantities to conduct the further detailed investigations, as quantification, structure analysis and pharmacological activity and toxicity testing. The metabolic activity of three mostly used Cunninghamella species in obtaining hydroxylated, dealkylated and oxidated metabolites of different drugs confirmed its convergence with human biotransformation. Though it cannot replace the standard methods, it can provide support in the field of biotransformation and identifying metabolic soft spots of new chemicals and in predicting possible metabolic pathways. Another aspect is the biosynthesis of metabolites. In this respect, techniques using Cunninghamella spp. seem to be competitive to the chemical methods currently used.

  7. Pretreatment and integrated analysis of spectral data reveal seaweed similarities based on chemical diversity.

    Science.gov (United States)

    Wei, Feifei; Ito, Kengo; Sakata, Kenji; Date, Yasuhiro; Kikuchi, Jun

    2015-03-03

    Extracting useful information from high dimensionality and large data sets is a major challenge for data-driven approaches. The present study was aimed at developing novel integrated analytical strategies for comprehensively characterizing seaweed similarities based on chemical diversity. The chemical compositions of 107 seaweed and 2 seagrass samples were analyzed using multiple techniques, including Fourier transform infrared (FT-IR) and solid- and solution-state nuclear magnetic resonance (NMR) spectroscopy, thermogravimetry-differential thermal analysis (TG-DTA), inductively coupled plasma-optical emission spectrometry (ICP-OES), CHNS/O total elemental analysis, and isotope ratio mass spectrometry (IR-MS). The spectral data were preprocessed using non-negative matrix factorization (NMF) and NMF combined with multivariate curve resolution-alternating least-squares (MCR-ALS) methods in order to separate individual component information from the overlapping and/or broad spectral peaks. Integrated analysis of the preprocessed chemical data demonstrated distinct discrimination of differential seaweed species. Further network analysis revealed a close correlation between the heavy metal elements and characteristic components of brown algae, such as cellulose, alginic acid, and sulfated mucopolysaccharides, providing a componential basis for its metal-sorbing potential. These results suggest that this integrated analytical strategy is useful for extracting and identifying the chemical characteristics of diverse seaweeds based on large chemical data sets, particularly complicated overlapping spectral data.

  8. Being similar while judging right and wrong: The effects of personal and situational similarity on moral judgements.

    Science.gov (United States)

    Pascal, Emilia

    2017-07-20

    This study investigated the effects of similarity with the transgressor and the victim on the perceived immorality of the transgression. Participants read two stories describing a person that cheated on their partner and a police officer that mistreated somebody. In the first story we manipulated participants' personal similarity to the transgressor and in the second their personal similarity to the victim. In each story, participants' past situational similarity to the target character was assessed according to their previous experiences of being in the same position. Results show that both personal and past situational similarity to the transgressor determine less severe moral judgements, while personal and past situational similarity with the victim have the opposite effect. We also tested several potential mediators of these effects, derived from competing theoretical accounts of the influence of similarity on perceived responsibility. Empathy emerged as mediating most of the effects of similarity on moral judgements, except those induced by past situational similarity with the victim. The foreseen probability of being in a similar situation mediated only the effects of similarity to the transgressor, and not those of similarity to the victim. Overall, results highlight the complex mechanisms of the influences of similarity on moral judgements. © 2017 International Union of Psychological Science.

  9. Multimodality imaging techniques.

    Science.gov (United States)

    Martí-Bonmatí, Luis; Sopena, Ramón; Bartumeus, Paula; Sopena, Pablo

    2010-01-01

    In multimodality imaging, the need to combine morphofunctional information can be approached by either acquiring images at different times (asynchronous), and fused them through digital image manipulation techniques or simultaneously acquiring images (synchronous) and merging them automatically. The asynchronous post-processing solution presents various constraints, mainly conditioned by the different positioning of the patient in the two scans acquired at different times in separated machines. The best solution to achieve consistency in time and space is obtained by the synchronous image acquisition. There are many multimodal technologies in molecular imaging. In this review we will focus on those multimodality image techniques more commonly used in the field of diagnostic imaging (SPECT-CT, PET-CT) and new developments (as PET-MR). The technological innovations and development of new tracers and smart probes are the main key points that will condition multimodality image and diagnostic imaging professionals' future. Although SPECT-CT and PET-CT are standard in most clinical scenarios, MR imaging has some advantages, providing excellent soft-tissue contrast and multidimensional functional, structural and morphological information. The next frontier is to develop efficient detectors and electronics systems capable of detecting two modality signals at the same time. Not only PET-MR but also MR-US or optic-PET will be introduced in clinical scenarios. Even more, MR diffusion-weighted, pharmacokinetic imaging, spectroscopy or functional BOLD imaging will merge with PET tracers to further increase molecular imaging as a relevant medical discipline. Multimodality imaging techniques will play a leading role in relevant clinical applications. The development of new diagnostic imaging research areas, mainly in the field of oncology, cardiology and neuropsychiatry, will impact the way medicine is performed today. Both clinical and experimental multimodality studies, in

  10. Providing Southern Perspectives on CSR

    DEFF Research Database (Denmark)

    Jeppesen, Søren; Kothuis, Bas

    of the key institutional issues affecting the CSR practices of SMEs. It presents perceptions of CSR practices among 21 SMEs in the garment industry in South Africa, based on 40 interviews with managers and 19 interviews with workers through the use of qualitative and quantitative interview frameworks....... It highlights a high degree of similarities between managers and workers, though knowledge of (cognitive level) the concept ‘CSR’ differ considerably. Informal practices are widespread and of key importance to the SMEs, expressed by managers and workers alike. History, industry and manager-workers relations...

  11. MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites.

    Science.gov (United States)

    O'Hagan, Steve; Kell, Douglas B

    2016-01-01

    endogenites. Overall, the Tversky similarity metrics provide a more useful range of examples of molecular similarity than does the simpler Tanimoto similarity, and help to draw attention to molecular similarities that would not be recognized if Tanimoto alone were used. Hence, the Tversky similarity metrics are likely to be of significant value in many general problems in cheminformatics.

  12. Effect of surfaces similarity on contact resistance of fractal rough surfaces under cyclic loading

    Science.gov (United States)

    Gao, Yuanwen; Liu, Limei; Ta, Wurui; Song, Jihua

    2018-03-01

    Although numerous studies have shown that contact resistance depends significantly on roughness and fractal dimension, it remains elusive how they affect contact resistance between rough surfaces. The interface similarity index is first proposed to describe the similarity of the contact surfaces, which gives a good indication of the actual contact area between surfaces. We reveal that the surfaces' similarity be an origin of contact resistance variation. The cyclic loading can increase the contact stiffness, and the contact stiffness increases with the increase of the interface similarity index. These findings explain the mechanism of surface roughness and fractal dimension on contact resistance, and also provide reference for the reliability design of the electrical connection.

  13. Survey of semantic modeling techniques

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.L.

    1975-07-01

    The analysis of the semantics of programing languages was attempted with numerous modeling techniques. By providing a brief survey of these techniques together with an analysis of their applicability for answering semantic issues, this report attempts to illuminate the state-of-the-art in this area. The intent is to be illustrative rather than thorough in the coverage of semantic models. A bibliography is included for the reader who is interested in pursuing this area of research in more detail.

  14. PERSONALISED DENTURES WITH BRANCHING TECHNIQUE

    OpenAIRE

    Puneet; Priyanka

    2012-01-01

    ABSTRACT: While the basic process of making dentures has chang ed little over the past several decades, new materials and techniques can help labor atories and clinicians provide functional, esthetic restorations that offer exceptional value t o patients. Unlike the conventional “linear” methods which foll ow specific steps in a cookbook fashion, the Branching Technique is a dynamic conce pt which can be adjusted to meet the clinical needs of each patient. Thi...

  15. Medicare Referring Provider DMEPOS PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset, which is part of CMSs Medicare Provider Utilization and Payment Data, details information on Durable Medical Equipment, Prosthetics, Orthotics and...

  16. TERRAIN, PROVIDENCE COUNTY, RHODE ISLAND

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Providence AOI consists of the costal portion of the county, and meshes up seamlessly with the Kent county AOI directly south. Ground Control is collected...

  17. Types of health care providers

    Science.gov (United States)

    ... article describes health care providers involved in primary care, nursing care, and specialty care. ... MD) or a Doctor of Osteopathic Medicine (DO). NURSING CARE Licensed practical nurses (LPNs) are state-licensed caregivers ...

  18. Calculation of Sentence Semantic Similarity Based on Syntactic Structure

    Directory of Open Access Journals (Sweden)

    Xiao Li

    2015-01-01

    Full Text Available Combined with the problem of single direction of the solution of the existing sentence similarity algorithms, an algorithm for sentence semantic similarity based on syntactic structure was proposed. Firstly, analyze the sentence constituent, then through analysis convert sentence similarity into words similarity on the basis of syntactic structure, then convert words similarity into concept similarity through words disambiguation, and, finally, realize the semantic similarity comparison. It also gives the comparison rules in more detail for the modifier words in the sentence which also have certain contributions to the sentence. Under the same test condition, the experiments show that the proposed algorithm is more intuitive understanding of people and has higher accuracy.

  19. Lodging Update: Providence, Rhode Island

    Directory of Open Access Journals (Sweden)

    Ragel Roginsky

    2013-04-01

    Full Text Available Each quarter, Pinnacle Advisory Group prepares an analysis of the New England lodging industry, which provides a regional summary and then focuses in depth on a particular market. These reviews look at recent and proposed supply changes, factors affecting demand and growth rates, and the effects of interactions between such supply and demand trends. In this issue, the authors spotlight the lodging market in Providence, Rhode Island.

  20. Elastography of the Breast: Imaging Techniques and Pitfalls in Interpretation

    International Nuclear Information System (INIS)

    Moon, Woo Kyung; Chang, Jung Min; Cho, Nariya

    2011-01-01

    Ultrasound (US) elastography is a tool that indicates the hardness of a lesion. Recent studies using elastography with freehand compression have shown similar diagnostic performance to conventional US in differentiating benign lesions from malignant breast masses. On the other hand, the acquired information is not quantitative, and the reliability of the imaging technique to correctly compress the tissue depends on the skill of the operator, resulting in substantial interobserver variability during data acquisition and interpretation. To overcome this, shear wave elastography was developed to provide quantitative information on the tissue elasticity. The system works by remotely inducing mechanical vibrations through the acoustic radiation force created by a focused US beam. This review discusses the principles and examination techniques of the two types of elastography systems and provides practical points to reduce the interobserver variability or errors during data acquisition and interpretation

  1. Point of Technique

    African Journals Online (AJOL)

    .

    hotmail.com. Introduction. Minimally invasive techniques are becoming popular choice for the recent times. These techniques are lowering the cost and giving the best cosmetic results. For cardiovascular surgery these techniques are much more.

  2. Extending the Similarity-Attraction Effect: The Effects of When-Similarity in Computer-Mediated Communication

    NARCIS (Netherlands)

    Kaptein, M.C.; Castaneda, D.; Fernandez, N.; Nass, C.

    2014-01-01

    The feeling of connectedness experienced in computer-mediated relationships can be explained by the similarity-attraction effect (SAE). Though SAE is well established in psychology, the effects of some types of similarity have not yet been explored. In 2 studies, we demonstrate similarity-attraction

  3. Cogeneration techniques; Les techniques de cogeneration

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-10-01

    This dossier about cogeneration techniques comprises 12 parts dealing successively with: the advantages of cogeneration (examples of installations, electrical and thermal efficiency); the combustion turbine (principle, performances, types); the alternative internal combustion engines (principle, types, rotation speed, comparative performances); the different configurations of cogeneration installations based on alternative engines and based on steam turbines (coal, heavy fuel and natural gas-fueled turbines); the environmental constraints of combustion turbines (pollutants, techniques of reduction of pollutant emissions); the environmental constraints of alternative internal combustion engines (gas and diesel engines); cogeneration and energy saving; the techniques of reduction of pollutant emissions (pollutants, unburnt hydrocarbons, primary and secondary (catalytic) techniques, post-combustion); the most-advanced configurations of cogeneration installations for enhanced performances (counter-pressure turbines, massive steam injection cycles, turbo-chargers); comparison between the performances of the different cogeneration techniques; the tri-generation technique (compression and absorption cycles). (J.S.)

  4. Classification of Myoviridae bacteriophages using protein sequence similarity

    Directory of Open Access Journals (Sweden)

    Ackermann Hans W

    2009-10-01

    Full Text Available Abstract Background We advocate unifying classical and genomic classification of bacteriophages by integration of proteomic data and physicochemical parameters. Our previous application of this approach to the entirely sequenced members of the Podoviridae fully supported the current phage classification of the International Committee on Taxonomy of Viruses (ICTV. It appears that horizontal gene transfer generally does not totally obliterate evolutionary relationships between phages. Results CoreGenes/CoreExtractor proteome comparison techniques applied to 102 Myoviridae suggest the establishment of three subfamilies (Peduovirinae, Teequatrovirinae, the Spounavirinae and eight new independent genera (Bcep781, BcepMu, FelixO1, HAP1, Bzx1, PB1, phiCD119, and phiKZ-like viruses. The Peduovirinae subfamily, derived from the P2-related phages, is composed of two distinct genera: the "P2-like viruses", and the "HP1-like viruses". At present, the more complex Teequatrovirinae subfamily has two genera, the "T4-like" and "KVP40-like viruses". In the genus "T4-like viruses" proper, four groups sharing >70% proteins are distinguished: T4-type, 44RR-type, RB43-type, and RB49-type viruses. The Spounavirinae contain the "SPO1-"and "Twort-like viruses." Conclusion The hierarchical clustering of these groupings provide biologically significant subdivisions, which are consistent with our previous analysis of the Podoviridae.

  5. Comparison of chromosome analysis using cell culture by coverslip technique with flask technique.

    Science.gov (United States)

    Sajapala, Suraphan; Buranawut, Kitti; NiwatArunyakasemsuk, Md

    2014-02-01

    To determine accuracy rate ofchromosome study from amniotic cellculture by coverslip technique compared with flask technique and to compared timing ofamniotic cell culture, amount ofamniotic cell culture media and cost ofamniotic cell culture. Cross sectional study. Department of Obstetrics and Gynecology, Phramongkutklao Hospital. Subjects: 70 pregnant women who underwent amniocentesis at Phramongkutklao Hospital during November 1, 2007 to February 29, 2008. Amniotic cell culture by flask technique and coverslip technique. Accuracy of amniotic cell culture for chromosome study by coverslip technique compared with flask technique. Totally 70 pregnant women who underwent to amniocentesis and dividedamniotic fluid to cell culture by flask technique and coverslip technique. 69 samples had similar resultfrom both techniques. The only one sample had cell culture failure inboth methods due to blood contamination. Accuracy in coverslip technique was 100% compared with flask technique. In timing of amniotic cell culture, amount ofamniotic cell culture media and cost of amniotic cell culture between 2 methods that coverslip technique was lesser than flask technique. There is statistically significant of accuracy in chromosome result between coverslip technique and flask technique. Coverslip technique was lesser than flask technique in timing, amniotic cell culture media and costs ofamniotic cell culture.

  6. Triplet correlations among similarly tuned cells impact population coding

    Directory of Open Access Journals (Sweden)

    Natasha Alexandra Cayco Gajic

    2015-05-01

    Full Text Available Which statistical features of spiking activity matter for how stimuli are encoded in neural populations? A vast body of work has explored how firing rates in individual cells and correlations in the spikes of cell pairs impact coding. Recent experiments have shown evidence for the existence of higher-order spiking correlations, which describe simultaneous firing in triplets and larger ensembles of cells; however, little is known about their impact on encoded stimulus information. Here, we take a first step toward closing this gap. We vary triplet correlations in small (approximately 10 cell neural populations while keeping single cell and pairwise statistics fixed at typically reported values. This connection with empirically observed lower-order statistics important, as it places strong constraints on the level of triplet correlations that can occur. For each value of triplet correlations, we estimate the performance of the neural population on a two-stimulus discrimination task. We find that the allowed changes in the level of triplet correlations can significantly enhance coding, in particular if triplet correlations differ for the two stimuli. In this scenario, triplet correlations must be included in order to accurately quantify the functionality of neural populations. When both stimuli elicit similar triplet correlations, however, pairwise models provide relatively accurate descriptions of coding accuracy. We explain our findings geometrically via the skew that triplet correlations induce in population-wide distributions of neural responses. Finally, we calculate how many samples are necessary to accurately measure spiking correlations of this type, providing an estimate of the necessary recording times in future experiments.

  7. A novel numerical framework for self-similarity in plasticity: Wedge indentation in single crystals

    Science.gov (United States)

    Juul, K. J.; Niordson, C. F.; Nielsen, K. L.; Kysar, J. W.

    2018-03-01

    A novel numerical framework for analyzing self-similar problems in plasticity is developed and demonstrated. Self-similar problems of this kind include processes such as stationary cracks, void growth, indentation etc. The proposed technique offers a simple and efficient method for handling this class of complex problems by avoiding issues related to traditional Lagrangian procedures. Moreover, the proposed technique allows for focusing the mesh in the region of interest. In the present paper, the technique is exploited to analyze the well-known wedge indentation problem of an elastic-viscoplastic single crystal. However, the framework may be readily adapted to any constitutive law of interest. The main focus herein is the development of the self-similar framework, while the indentation study serves primarily as verification of the technique by comparing to existing numerical and analytical studies. In this study, the three most common metal crystal structures will be investigated, namely the face-centered cubic (FCC), body-centered cubic (BCC), and hexagonal close packed (HCP) crystal structures, where the stress and slip rate fields around the moving contact point singularity are presented.

  8. Choosing a health care provider.

    Science.gov (United States)

    Harris, Katherine M; Beeuwkes Buntin, Melinda

    2008-05-01

    In a consumer-driven health care model, consumers, armed with information, would select providers based on quality and cost, thus increasing competition. This synthesis examines the availability of quality information and the evidence of how consumers use such information to choose a provider. Key findings include: information is publicly available from multiple sources regarding hospitals, but not individual doctors. Hospital information is predominantly made available online; but this limits awareness and access. Awareness is low overall, but highest among well-educated, healthy people. Even when consumers are aware of the data available, they rarely use it because they do not find it relevant: they do not foresee needing a hospital soon; are happy with their current provider; or did not find information pertinent to their specific health condition or hospital. While there is some evidence that hospitals that do poorly on public quality scorecards lose market share, there is better evidence that the providers themselves react to the quality scores by addressing care problems. Studies consistently show that consumers value health care quality and want information, but instead they rely on input from friends, family and their personal physicians about the quality of providers.

  9. Ancillary Services Provided from DER

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, J.B.

    2005-12-21

    Distributed energy resources (DER) are quickly making their way to industry primarily as backup generation. They are effective at starting and then producing full-load power within a few seconds. The distribution system is aging and transmission system development has not kept up with the growth in load and generation. The nation's transmission system is stressed with heavy power flows over long distances, and many areas are experiencing problems in providing the power quality needed to satisfy customers. Thus, a new market for DER is beginning to emerge. DER can alleviate the burden on the distribution system by providing ancillary services while providing a cost adjustment for the DER owner. This report describes 10 types of ancillary services that distributed generation (DG) can provide to the distribution system. Of these 10 services the feasibility, control strategy, effectiveness, and cost benefits are all analyzed as in the context of a future utility-power market. In this market, services will be provided at a local level that will benefit the customer, the distribution utility, and the transmission company.

  10. Ecosystem services provided by waterbirds.

    Science.gov (United States)

    Green, Andy J; Elmberg, Johan

    2014-02-01

    Ecosystem services are ecosystem processes that directly or indirectly benefit human well-being. There has been much recent literature identifying different services and the communities and species that provide them. This is a vital first step towards management and maintenance of these services. In this review, we specifically address the waterbirds, which play key functional roles in many aquatic ecosystems, including as predators, herbivores and vectors of seeds, invertebrates and nutrients, although these roles have often been overlooked. Waterbirds can maintain the diversity of other organisms, control pests, be effective bioindicators of ecological conditions, and act as sentinels of potential disease outbreaks. They also provide important provisioning (meat, feathers, eggs, etc.) and cultural services to both indigenous and westernized societies. We identify key gaps in the understanding of ecosystem services provided by waterbirds and areas for future research required to clarify their functional role in ecosystems and the services they provide. We consider how the economic value of these services could be calculated, giving some examples. Such valuation will provide powerful arguments for waterbird conservation. © 2013 The Authors. Biological Reviews © 2013 Cambridge Philosophical Society.

  11. Similarity of High-Resolution Tandem Mass Spectrometry Spectra of Structurally Related Micropollutants and Transformation Products

    Science.gov (United States)

    Schollée, Jennifer E.; Schymanski, Emma L.; Stravs, Michael A.; Gulde, Rebekka; Thomaidis, Nikolaos S.; Hollender, Juliane

    2017-12-01

    High-resolution tandem mass spectrometry (HRMS2) with electrospray ionization is frequently applied to study polar organic molecules such as micropollutants. Fragmentation provides structural information to confirm structures of known compounds or propose structures of unknown compounds. Similarity of HRMS2 spectra between structurally related compounds has been suggested to facilitate identification of unknown compounds. To test this hypothesis, the similarity of reference standard HRMS2 spectra was calculated for 243 pairs of micropollutants and their structurally related transformation products (TPs); for comparison, spectral similarity was also calculated for 219 pairs of unrelated compounds. Spectra were measured on Orbitrap and QTOF mass spectrometers and similarity was calculated with the dot product. The influence of different factors on spectral similarity [e.g., normalized collision energy (NCE), merging fragments from all NCEs, and shifting fragments by the mass difference of the pair] was considered. Spectral similarity increased at higher NCEs and highest similarity scores for related pairs were obtained with merged spectra including measured fragments and shifted fragments. Removal of the monoisotopic peak was critical to reduce false positives. Using a spectral similarity score threshold of 0.52, 40% of related pairs and 0% of unrelated pairs were above this value. Structural similarity was estimated with the Tanimoto coefficient and pairs with higher structural similarity generally had higher spectral similarity. Pairs where one or both compounds contained heteroatoms such as sulfur often resulted in dissimilar spectra. This work demonstrates that HRMS2 spectral similarity may indicate structural similarity and that spectral similarity can be used in the future to screen complex samples for related compounds such as micropollutants and TPs, assisting in the prioritization of non-target compounds. [Figure not available: see fulltext.

  12. Free-classification of perceptually similar speakers with dysarthria.

    Science.gov (United States)

    Lansford, Kaitlin L; Liss, Julie M; Norton, Rebecca E

    2014-12-01

    In this investigation, the construct of perceptual similarity was explored in the dysarthrias. Specifically, we employed an auditory free-classification task to determine whether listeners could cluster speakers by perceptual similarity, whether the clusters mapped to acoustic metrics, and whether the clusters were constrained by dysarthria subtype diagnosis. Twenty-three listeners blinded to speakers' medical and dysarthria subtype diagnoses participated. The task was to group together (drag and drop) the icons corresponding to 33 speakers with dysarthria on the basis of how similar they sounded. Cluster analysis and multidimensional scaling (MDS) modeled the perceptual dimensions underlying similarity. Acoustic metrics and perceptual judgments were used in correlation analyses to facilitate interpretation of the derived dimensions. Six clusters of similar-sounding speakers and 3 perceptual dimensions underlying similarity were revealed. The clusters of similar-sounding speakers were not constrained by dysarthria subtype diagnosis. The 3 perceptual dimensions revealed by MDS were correlated with metrics for articulation rate, intelligibility, and vocal quality, respectively. This study shows (a) feasibility of a free-classification approach for studying perceptual similarity in dysarthria, (b) correspondence between acoustic and perceptual metrics to clusters of similar-sounding speakers, and (c) similarity judgments transcended dysarthria subtype diagnosis.

  13. An experimental test of the persuasive effect of source similarity in narrative and nonnarrative health blogs.

    Science.gov (United States)

    Lu, Amy Shirong

    2013-07-25

    Blogs, or websites containing online personal journals, are a form of popular personal communication with immense potential for health promotion. Narratives are stories with a beginning, middle, and end that provide information about the characters and plot. Source similarity refers to the degree to which the message source and each recipient are alike with respect to certain attributes. Narratives and source similarity have seldom been examined in tandem as strategies for health persuasion. Personal health blogs provide a suitable platform for such an investigation. This study examined the persuasive effects of message type and source similarity on participants' intentions to adopt a specific health behavior (running for exercise). A total of 150 participants were randomly assigned to conditions (n=25 per condition) in a completely crossed, 2 (message type: narrative and nonnarrative) × 3 (source similarity: no similarity, non-health-related similarity, and health-related similarity) between-subjects experiment. First, in an online questionnaire, participants provided personal information in 42 categories and rated the relatedness of each category to running and then completed pretest measures of the dependent variables. Based on their responses, 150 personal health blogs were created. Two weeks later, the initial participants read the blog created with their personal characteristics and completed a questionnaire online. The source similarity effect was stronger in nonnarrative than narrative blogs. When the blogs were nonnarrative, those with health-related similarities were more persuasive than those with non-health-related similarities. Narrative blogs generated more positive thoughts and stronger blogger identification than nonnarrative blogs. Health-related source similarity is key for persuasive health communication, especially when the messages are nonnarrative.

  14. Tumescent mastectomy technique in autologous breast reconstruction.

    Science.gov (United States)

    Vargas, Christina R; Koolen, Pieter G L; Ho, Olivia A; Ricci, Joseph A; Tobias, Adam M; Lin, Samuel J; Lee, Bernard T

    2015-10-01

    Use of the tumescent mastectomy technique has been reported to facilitate development of a hydrodissection plane, reduce blood loss, and provide adjunct analgesia. Previous studies suggest that tumescent dissection may contribute to adverse outcomes after immediate implant reconstruction; however, its effect on autologous microsurgical reconstruction has not been established. A retrospective review was conducted of all immediate microsurgical breast reconstruction procedures at a single academic center between January 2004 and December 2013. Records were queried for age, body mass index, mastectomy weight, diabetes, hypertension, smoking, preoperative radiation, reconstruction flap type, and autologous flap weight. Outcomes of interest were mastectomy skin necrosis, complete and partial flap loss, return to the operating room, breast hematoma, seroma, and infection. There were 730 immediate autologous breast reconstructions performed during the study period; 46% with the tumescent dissection technique. Groups were similar with respect to baseline patient and procedural characteristics. Univariate analysis revealed no significant difference in the incidence of mastectomy skin necrosis, complete or partial flap loss, return to the operating room, operative time, estimated blood loss, recurrence, breast hematoma, seroma, or infection in patients undergoing tumescent mastectomy. Multivariate analysis also demonstrated no significant association between the use of tumescent technique and postoperative breast mastectomy skin necrosis (P = 0.980), hematoma (P = 0.759), or seroma (P = 0.340). Use of the tumescent dissection technique during mastectomy is not significantly associated with adverse outcomes after microsurgical breast reconstruction. Despite concern for its impact on implant reconstruction, our findings suggest that this method can be used safely preceding autologous procedures. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Machine for development impact tests in sports seats and similar

    Science.gov (United States)

    Gonçalves, R. M.

    2015-10-01

    This paper describes the stages of development of a machine to perform impact tests in sport seats, seats for spectators and multiple seats. This includes reviews and recommendations for testing laboratories that have needs similar to the laboratory where unfolded this process.The machine was originally developed seeking to meet certain impact tests in accordance with the NBR15925 standards; 15878 and 16031. The process initially included the study of the rules and the election of the tests for which the machine could be developed and yet all reports and outcome of interaction with service providers and raw materials.For operating facility, it was necessary to set entirely the machine control, which included the concept of dialogue with operator, the design of the menu screens and the procedures for submission and registration of results. To ensure reliability in the process, the machine has been successfully calibrated according to the requirements of the Brazilian network of calibration.The criticism to this enterprise covers the technical and economic aspects involved and points out the main obstacles that were needed to overcome.

  16. Decoding the similarities and differences among mycobacterial species.

    Directory of Open Access Journals (Sweden)

    Sony Malhotra

    2017-08-01

    Full Text Available Mycobacteriaceae comprises pathogenic species such as Mycobacterium tuberculosis, M. leprae and M. abscessus, as well as non-pathogenic species, for example, M. smegmatis and M. thermoresistibile. Genome comparison and annotation studies provide insights into genome evolutionary relatedness, identify unique and pathogenicity-related genes in each species, and explore new targets that could be used for developing new diagnostics and therapeutics. Here, we present a comparative analysis of ten-mycobacterial genomes with the objective of identifying similarities and differences between pathogenic and non-pathogenic species. We identified 1080 core orthologous clusters that were enriched in proteins involved in amino acid and purine/pyrimidine biosynthetic pathways, DNA-related processes (replication, transcription, recombination and repair, RNA-methylation and modification, and cell-wall polysaccharide biosynthetic pathways. For their pathogenicity and survival in the host cell, pathogenic species have gained specific sets of genes involved in repair and protection of their genomic DNA. M. leprae is of special interest owing to its smallest genome (1600 genes and ~1300 psuedogenes, yet poor genome annotation. More than 75% of the pseudogenes were found to have a functional ortholog in the other mycobacterial genomes and belong to protein families such as transferases, oxidoreductases and hydrolases.

  17. Dimensions Underlying the Perceived Similarity of Acoustic Environments

    Directory of Open Access Journals (Sweden)

    Francesco Aletta

    2017-07-01

    Full Text Available Scientific research on how people perceive or experience and/or understand the acoustic environment as a whole (i.e., soundscape is still in development. In order to predict how people would perceive an acoustic environment, it is central to identify its underlying acoustic properties. This was the purpose of the present study. Three successive experiments were conducted. With the aid of 30 university students, the first experiment mapped the underlying dimensions of perceived similarity among 50 acoustic environments, using a visual sorting task of their spectrograms. Three dimensions were identified: (1 Distinguishable–Indistinguishable sound sources, (2 Background–Foreground sounds, and (3 Intrusive–Smooth sound sources. The second experiment was aimed to validate the results from Experiment 1 by a listening experiment. However, a majority of the 10 expert listeners involved in Experiment 2 used a qualitatively different approach than the 30 university students in Experiment 1. A third experiment was conducted in which 10 more expert listeners performed the same task as per Experiment 2, with spliced audio signals. Nevertheless, Experiment 3 provided a statistically significantly worse result than Experiment 2. These results suggest that information about the meaning of the recorded sounds could be retrieved in the spectrograms, and that the meaning of the sounds may be captured with the aid of holistic features of the acoustic environment, but such features are still unexplored and further in-depth research is needed in this field.

  18. Similarities and differences in values between Vietnamese parents and adolescents

    Directory of Open Access Journals (Sweden)

    Truong Thi Khanh Ha

    2015-07-01

    Full Text Available Background The purpose of this study was to analyse similarities and differences in the motivational value system of Vietnamese parents and adolescents, in the context of Schwartz’s value theory. Also, the transmission of values between two generations was studied. Participants and procedure The study was performed in three different cities of Vietnam – Hanoi, Hue and Ho Chi Minh City – on adolescents, their fathers and mothers (N = 2226. The hierarchy of values was measured with a Vietnamese version of the Portrait Value Questionnaire (PVQ-40. Additionally, expectations of parents toward children and preferences of children were measured with a list of 28 features and attitudes prepared for the study. Results The results show that both parents and their adolescent children highly respect universalism, conformity, and benevolence in contrast to power and stimulation, which is still typical for a collectivistic culture. The differences arise in higher-order values: while parents value conservatism (security, conformity and tradition, their children prefer more openness to change (self-direction and hedonism values, which is typical for a more individualistic culture. The results also reveal that parents in Vietnam expect and transfer to children some attitudes and features such as studiousness, filial piety and diligence, but not riskiness, desire or humour. Although adolescents are aware of their parents’ expectations, they do not fully accept them. Conclusions The results provide hints for parents to plan their strategy on appropriate education of their children, in the current context of global integration and cultural changes.

  19. Machine for development impact tests in sports seats and similar

    International Nuclear Information System (INIS)

    Gonçalves, R M

    2015-01-01

    This paper describes the stages of development of a machine to perform impact tests in sport seats, seats for spectators and multiple seats. This includes reviews and recommendations for testing laboratories that have needs similar to the laboratory where unfolded this process.The machine was originally developed seeking to meet certain impact tests in accordance with the NBR15925 standards; 15878 and 16031. The process initially included the study of the rules and the election of the tests for which the machine could be developed and yet all reports and outcome of interaction with service providers and raw materials.For operating facility, it was necessary to set entirely the machine control, which included the concept of dialogue with operator, the design of the menu screens and the procedures for submission and registration of results. To ensure reliability in the process, the machine has been successfully calibrated according to the requirements of the Brazilian network of calibration.The criticism to this enterprise covers the technical and economic aspects involved and points out the main obstacles that were needed to overcome. (paper)

  20. Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures.

    Science.gov (United States)

    Someswara Rao, Chinta; Viswanadha Raju, S

    2016-03-01

    In this paper, we consider correlation coefficient, rank correlation coefficient and cosine similarity measures for evaluating similarity between Homo sapiens and monkeys. We used DNA chromosomes of genome wide genes to determine the correlation between the chromosomal content and evolutionary relationship. The similarity among the H. sapiens and monkeys is measured for a total of 210 chromosomes related to 10 species. The similarity measures of these different species show the relationship between the H. sapiens and monkey. This similarity will be helpful at theft identification, maternity identification, disease identification, etc.