WorldWideScience

Sample records for technical delivery conditions

  1. Hydrogen Delivery Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The mission of the Hydrogen Delivery Technical Team (HDTT) is to enable the development of hydrogen delivery technologies, which will allow for fuel cell competitiveness with gasoline and hybrid technologies by achieving an as-produced, delivered, and dispensed hydrogen cost of $2-$4 per gallon of gasoline equivalent of hydrogen.

  2. Conceptual and technical aspects of transfection and gene delivery.

    Science.gov (United States)

    Kaestner, Lars; Scholz, Anke; Lipp, Peter

    2015-03-15

    Genetically modified animals are state of the art in biomedical research as gene therapy is a promising perspective in the attempt to cure hereditary diseases. Both approaches have in common that modified or corrected genetic information must be transferred into cells in general or into particular cell types of an organism. Here we give an overview of established and emerging methods of transfection and gene delivery and provide conceptual and technical advantages and drawbacks of their particular use. Additionally, based on a flow chart, we compiled a rough guideline to choose a gene transfer method for a particular field of application. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Technical and logistic provisions for the delivery of radioactive wastes in the final repository Konrad

    International Nuclear Information System (INIS)

    Poeppinghaus, Jens

    2013-01-01

    The beginning of radioactive waste delivery to the final repository Konrad is planned for 2019. The main issue for the technical and logistic provisions is the development of a concept for the transport of the licensed radioactive waste containers to the site, including a turning concept for cylindrical waste forms and planning, construction and manufacture of transport equipment. Further issues include a logistic concept considering specific boundary conditions as administrative processes, priorities, special features of the delivering institutions and technical requirements of the repository.

  4. Technical Evaluation Report 5: Classification of DE Delivery Systems

    Directory of Open Access Journals (Sweden)

    Diane Belyk

    2002-01-01

    Full Text Available For their optimal use in distance education (DE, online educational applications need to be integrated within a comprehensive course management system (CMS. Such systems are server-based software that supports the development, delivery, administration, and evaluation of online learning environments. The selection of an appropriate CMS should be considered from the multiple perspectives of the student, the course developer, the course instructor/ tutor, the technical support staff, and the DE institution’s administration. The current evaluation of CMS packages was conducted by a team of individuals with experience and contacts in relation to each of these DE user types. The report compares a series of CMS packages in terms of their range of features, and in relation to their satisfaction of international online education standards.

  5. Vocational technical and adult education: Status, trends and issues related to electronic delivery

    Science.gov (United States)

    Rothenberg, D.

    1973-01-01

    Data are analyzed, and trends and issues are discussed to provide information useful to the systems designer who wishes to identify and assess the opportunities for large scale electronic delivery in vocational/technical and adult education. Issues connected with vocational/technical education are investigated, with emphasis on those issues in the current spotlight which are relevant to the possibilities of electronic delivery. The current role of media is examined in vocational/technical instruction.

  6. [Recent technical advances in portable oxygen delivery systems].

    Science.gov (United States)

    Machida, K; Kawabe, Y; Mori, M; Haga, T

    1992-08-01

    According to a Japanese national survey (June 30, 1990), the number of patients receiving home oxygen therapy (HOT) has been greater than 18,000 since March 1985, when HOT was first covered by health insurance. The oxygen concentrator, especially the molecular sieve type, is the most common method of delivery (more than 90%). In April 1988, the portable oxygen cylinder was acknowledged by health insurance, and the liquid oxygen supply system in April 1990. Three types of portable oxygen delivery systems are available; oxygen cyclinder, liquid oxygen system, and oxygen concentrator (membrane type), of which the oxygen cylinder is most commonly used. In our hospital, portable oxygen supply systems were used in 80% of 168 HOT cases in 1990, and the use of 400 L aluminum oxygen cylinders at a flow rate of 1-2 L/min has been most popular. There is an strong desire from patients for lighter portable oxygen supply system of longer duration. In 19 patients with chronic respiratory failure, we evaluated a newly designed demand oxygen delivery system (DODS), which weighs 2.4 kg including the DOD device (TER-20 Teijin), 1.1 L oxygen cylinder made of ultressor, nasal cannula, and carrier. Arterial blood gases at rest (room air) were PaO2 61.9 +/- 6.3 torr, PaCO2 63.8 +/- 9.4 torr and pH 7.40 +/- 0.04. A crossover trial was performed under three conditions; breathing room air with no weight, and pulse oxygen flow and continuous oxygen flow each carrying 2.4 kg of weight. Both 6 minute walking (E1) and walking on a slow speed treadmill (E2) were studied.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Design and Delivery of Technical Module for the Business Intelligence Course

    Science.gov (United States)

    Wang, Shouhong; Wang, Hai

    2013-01-01

    IS programs are increasingly being called on to offer courses in business intelligence. This article presents the pedagogical design and the delivery method of a practicable technical module for a non-technically oriented Business Intelligence course. It is a tutorial for the instructors who wish to incorporate a practical technical element in…

  8. Technical Barriers, Gaps,and Opportunities Related to Home Energy Upgrade Market Delivery

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Marcus V.A. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2011-11-01

    This report outlines the technical barriers, gaps, and opportunities that arise in executing home energy upgrade market delivery approaches, as identified through research conducted by the U.S. Department of Energy's Building America program.

  9. Electron Conditioning of Technical Aluminium Surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Le Pimpec, F

    2004-09-02

    The effect of electron conditioning on commercially aluminium alloys 1100 and 6063 were investigated. Contrary to the assumption that electron conditioning, if performed long enough, can reduce and stabilize the SEY to low values (= 1.3, value of many pure elements [1]), the SEY of aluminium did not go lower than 1.8. In fact, it reincreases with continued electron exposure dose.

  10. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Science.gov (United States)

    2010-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  11. Methodology for quantitative assessment of technical condition in industrial systems

    Energy Technology Data Exchange (ETDEWEB)

    Steinbach, C. [Marintek AS (Norway); Soerli, A. [Statoil (Norway)

    1998-12-31

    As part of the Eureka project Ageing Management a methodology has been developed to assess the technical condition of industrial systems. The first part of the presentation argues for the use of technical condition parameters in the context of maintenance strategies. Thereafter the term `technical condition` is defined more thoroughly as it is used within the project. It is claimed that the technical condition of a system - such as a feed water system of a nuclear power plant, or a water injection system on an oil platform - may be determined by aggregating the condition of its smaller components using a hierarchic approach. The hierarchy has to be defined in co-operation with experienced personnel and reflects the impact of degradation of elements on a lower level to nodes higher in the hierarchy. The impact is divided into five categories with respect to safety, environment, availability, costs and man-hours. To determine the technical condition of the bottom elements of the hierarchy, available data is used from both an on-line condition monitoring system and maintenance history. The second part of the presentation introduces the prototype software tool TeCoMan which utilises the theory and applies it to installations of the participating companies. First results and gained experiences with the method and tool are discussed. (orig.)

  12. Methodology for quantitative assessment of technical condition in industrial systems

    Energy Technology Data Exchange (ETDEWEB)

    Steinbach, C [Marintek AS (Norway); Soerli, A [Statoil (Norway)

    1999-12-31

    As part of the Eureka project Ageing Management a methodology has been developed to assess the technical condition of industrial systems. The first part of the presentation argues for the use of technical condition parameters in the context of maintenance strategies. Thereafter the term `technical condition` is defined more thoroughly as it is used within the project. It is claimed that the technical condition of a system - such as a feed water system of a nuclear power plant, or a water injection system on an oil platform - may be determined by aggregating the condition of its smaller components using a hierarchic approach. The hierarchy has to be defined in co-operation with experienced personnel and reflects the impact of degradation of elements on a lower level to nodes higher in the hierarchy. The impact is divided into five categories with respect to safety, environment, availability, costs and man-hours. To determine the technical condition of the bottom elements of the hierarchy, available data is used from both an on-line condition monitoring system and maintenance history. The second part of the presentation introduces the prototype software tool TeCoMan which utilises the theory and applies it to installations of the participating companies. First results and gained experiences with the method and tool are discussed. (orig.)

  13. Identification of mine rescue equipment reduction gears technical condition

    Science.gov (United States)

    Gerike, B. L.; Klishin, V. I.; Kuzin, E. G.

    2017-09-01

    The article presents the reasons for adopting intelligent service of mine belt conveyer drives concerning evaluation of their technical condition based on the diagnostic techniques instead of regular preventative maintenance. The article reveals the diagnostic results of belt conveyer drive reduction gears condition taking into account the parameters of lubricating oil, vibration and temperature. Usage of a complex approach to evaluate technical conditions allows reliability of the forecast to be improved, which makes it possible not only to prevent accidental breakdowns and eliminate unscheduled downtime, but also to bring sufficient economic benefits through reduction of the term and scope of work during overhauls.

  14. IMPORTANCE OF DELIVERY CONDITIONS IN THE EXTERNAL PRICE CALCULATION

    Directory of Open Access Journals (Sweden)

    Violeta ISAI

    2005-01-01

    Full Text Available The delivery conditions of the merchandise at export, established by the rules INCOTERMS2000, influence the external price structure. There are some conditions in which the external priceincludes only the value of the merchandise and other conditions in which, besides the value of themerchandise, the price includes also the external transport and insurance. In the case of the exportson commercial credit, when it appears the notion of external interest, this one may be included in theprice or may be invoiced separately, thus defining gross external prices and net external prices.

  15. Identifying Technical Condition of Vehicle Gearbox Using Acoustic Emission

    Science.gov (United States)

    Furch, Jan; Glos, Josef

    2017-06-01

    The article examines the technical condition of rotating parts using acoustic diagnostics. The measured object was a mechanical transmission of a field vehicle. Recently this method has been developing very quickly and is expected to be used not only for the signal analysis itself, but also for the failure occurrence prediction which is our aim in the future. In our article we observe the technical condition of a four-speed transmission and analyse the acoustic signal expressed by the root mean square of a noise level in decibels.

  16. Conditions of Employment of Technical/Vocational Teachers.

    Science.gov (United States)

    Abrillo, Harry

    A study examined the job requirements and working conditions of vocational and technical education teachers (VTETs) in India, Indonesia, Malaysia, Singapore, and Thailand. Data were gathered (1) from published materials and interviews with officers and staff of concerned agencies and (2) from a project-developed questionnaire that was administered…

  17. Health condition and residual life of deteriorating technical systems

    Energy Technology Data Exchange (ETDEWEB)

    Reinertsen, Rune

    1998-12-31

    Many offshore installations in the Norwegian Sector of the North Sea approach the end of their useful life. The same is true of many power plants and technical systems in general. This thesis describes the theory and improves the methods for the determination of the health condition and residual life of technical systems. Rather than developing new methods it discusses new ways of using existing statistical methods. The main contributions are: (1) A survey of the literature of diagnosis, prediction and life extension for deteriorating technical systems, (2) A discussion of some consequences of selecting the wrong life model, (3) A description of problems related to the determination of mean residual life of non-repairable technical systems, (4) Presentation of the concept of `technical health` to describe the soundness of a system exposed to failure mechanisms, (5) A model for predicting the technical health and residual life of a corroding system, (6) Recommends requirements and methods for using expert knowledge in safety and reliability analysis, (7) A general inspection strategy for system fault diagnosis by using Shannon entropy, (8) Points out weaknesses and strengths of risk measures used in the offshore industry today. 237 refs., 23 figs., 6 tabs.

  18. Health condition and residual life of deteriorating technical systems

    Energy Technology Data Exchange (ETDEWEB)

    Reinertsen, Rune

    1997-12-31

    Many offshore installations in the Norwegian Sector of the North Sea approach the end of their useful life. The same is true of many power plants and technical systems in general. This thesis describes the theory and improves the methods for the determination of the health condition and residual life of technical systems. Rather than developing new methods it discusses new ways of using existing statistical methods. The main contributions are: (1) A survey of the literature of diagnosis, prediction and life extension for deteriorating technical systems, (2) A discussion of some consequences of selecting the wrong life model, (3) A description of problems related to the determination of mean residual life of non-repairable technical systems, (4) Presentation of the concept of `technical health` to describe the soundness of a system exposed to failure mechanisms, (5) A model for predicting the technical health and residual life of a corroding system, (6) Recommends requirements and methods for using expert knowledge in safety and reliability analysis, (7) A general inspection strategy for system fault diagnosis by using Shannon entropy, (8) Points out weaknesses and strengths of risk measures used in the offshore industry today. 237 refs., 23 figs., 6 tabs.

  19. Web-Conferencing: An Analysis of Course Delivery Systems on Student Achievement at a Technical College

    Science.gov (United States)

    Stanford, Roger John

    2012-01-01

    Web-conferencing software was chosen for course delivery to provide flexible options for students at a two-year technical college. Students used technology to access a live, synchronous microeconomics course over the internet instead of a traditional face-to-face lecture. This investigation studied the impact of implementing web-conferencing…

  20. Effect of multipactor conditioning on technical electrode surfaces

    International Nuclear Information System (INIS)

    Graves, T. P.; Spektor, R.; Stout, P.

    2009-01-01

    Historically, multipactor conditioning has been utilized to remove surface contaminants from rf electrodes by electron-stimulated gas desorption, and such conditioning has been shown to reduce multipactor susceptibility. Multipactor threshold improvements are due to increasing E 1 , the minimum energy for the secondary electron coefficient, δ>1, such that resonant electrons are incapable of producing discharge-sustaining secondary emission. Using an rf amplitude sweep technique, the evolution of the multipactor threshold is measured as a function of multipactor conditioning time for a series of technical electrode surfaces. Results show over +3 dB of threshold improvement in copper and gold electrodes, while the aluminum threshold actually decreases with conditioning exposure. Additionally, these conditioning results indicate the possible voltage region for transient-mode multipaction (TMM), which can cause significant risk to rf systems such as space satellite components for which in-situ conditioning is generally not possible. Experimental results and supporting Monte Carlo particle tracking simulation results are presented.

  1. Optimization of conditions for gene delivery system based on PEI

    Directory of Open Access Journals (Sweden)

    Roya Cheraghi

    2017-01-01

    Full Text Available Objective(s: PEI based nanoparticle (NP due to dual capabilities of proton sponge and DNA binding is known as powerful tool for nucleic acid delivery to cells. However, serious cytotoxicity and complicated conditions, which govern NPs properties and its interactions with cells practically, hindered achievement to high transfection efficiency. Here, we have tried to optimize the properties of PEI/ firefly luciferase plasmid complexes and cellular condition to improve transfection efficiency. Materials and Methods: For this purpose, firefly luciferase, as a robust gene reporter, was complexed with PEI to prepare NPs with different size and charge. The physicochemical properties of nanoparticles were evaluated using agarose gel retardation and dynamic light scattering.  MCF7 and BT474 cells at different confluency were also transfected with prepared nanoparticles at various concentrations for short and long times. Results: The branched PEI can instantaneously bind to DNA and form cationic NPs. The results demonstrated the production of nanoparticles with size about 100-500 nm dependent on N/P ratio. Moreover, increase of nanoparticles concentration on the cell surface drastically improved the transfection rate, so at a concentration of 30 ng/ìl, the highest transfection efficiency was achieved. On the other side, at confluency between 40-60%, the maximum efficiency was obtained. The result demonstrated that N/P ratio of 12 could establish an optimized ratio between transfection efficiency and cytotoxicity of PEI/plasmid nanoparticles. The increase of NPs N/P ratio led to significant cytotoxicity. Conclusion: Obtained results verified the optimum conditions for PEI based gene delivery in different cell lines.

  2. Can branding by health care provider organizations drive the delivery of higher technical and service quality?

    Science.gov (United States)

    Snihurowych, Roman R; Cornelius, Felix; Amelung, Volker Eric

    2009-01-01

    Despite the widespread use of branding in nearly all other major industries, most health care service delivery organizations have not fully embraced the practices and processes of branding. Facilitating the increased and appropriate use of branding among health care delivery organizations may improve service and technical quality for patients. This article introduces the concepts of branding, as well as making the case that the use of branding may improve the quality and financial performance of organizations. The concepts of branding are reviewed, with examples from the literature used to demonstrate their potential application within health care service delivery. The role of branding for individual organizations is framed by broader implications for health care markets. Branding strategies may have a number of positive effects on health care service delivery, including improved technical and service quality. This may be achieved through more transparent and efficient consumer choice, reduced costs related to improved patient retention, and improved communication and appropriateness of care. Patient satisfaction may be directly increased as a result of branding. More research into branding could result in significant quality improvements for individual organizations, while benefiting patients and the health system as a whole.

  3. PARAMETRIC DIAGNOSTICS OF THE CENTRIFUGAL SUPERCHARGER'S TECHNICAL CONDITION DURING OPERATION

    Directory of Open Access Journals (Sweden)

    Regina A. Khuramshina

    2017-01-01

    Full Text Available Abstract. Objectives The main aim is to develop a mathematical model of a centrifugal compressor and carry out a parametric diagnostics of a centrifugal supercharger's technical condition during operation. Methods  A model is proposed for calculating the thermodynamic properties of natural gas, reducing the parameters of a centrifugal compressor to the initial conditions and to the rotation frequency, as well as the integral indicators of the supercharger's technical state. The technical state of the gas path of the centrifugal supercharger of the compressor unit is determined by the parametric diagnostic method. Results  The software implementation of the mathematical model of centrifugal compressor is carried out using a DVIGwT PC. The analysis of calculations indicates that the model is appropriate, with the error being due to taking into account the properties of iso-butane and i-hexane, in contrast with the VNIIGAZ technique. The evaluation studies of a centrifugal compressor's state are indicative of the presence or absence of its defects. Conclusion  Among a number of the diagnostic methods for evaluating a centrifugal supercharger, the most effective is vibrodiagnostics. However, the search for malfunctions and nascent defects in the flowing part of the centrifugal compressor cannot be limited only to vibrodiagnostic data, which provides about 60% of the reliable information about the state of the gas-air tract. About 20% of the compressor's malfunctions and approximately half of the dangerous modes of the supercharger's flow-through part is detected using thermogasdynamic parametric analysis (parametric diagnostics. The main difficulty of the control over the technical state of the flow-through part of the centrifugal supercharger is in the complication of the quantitative evaluation of the processes taking place in the supercharger, which leads to problems in providing reliable diagnosis during a reasonable period of time.

  4. Technical conditions for sustainable growth in economic theory. An analysis

    International Nuclear Information System (INIS)

    Granda C, Catalina

    2008-01-01

    Economic theory and its models point out returns to scale, substitution among productive factors and technological progress as conditions for sustainable growth. This work aims at a critical appraisal of these conditions, particularly the ones related to substitution between natural resources and manmade capital and technical change, by recognizing the inevitable physical scarcity of resources concomitant to the human actions in a world governed by hemodynamic restrictions. To do so, the role that the mentioned conditions play in the theories of economic growth with resources is analyzed, and its limitations and objections from a biophysical perspective are indicated as well. Finally, a brief consideration as to how inappropriate the theoretical representations of economic activities are to take account of growth in spite of resource exhaustion or degradation is carried out

  5. Technical Barriers, Gaps, and Opportunities Related to Home Energy Upgrade Market Delivery

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, M. V. A.

    2011-11-01

    This report outlines the technical barriers, gaps, and opportunities that arise in executing home energy upgrade market delivery approaches, as identified through research conducted by the U.S. Department of Energy's Building America program. The objective of this report is to outline the technical1 barriers, gaps, and opportunities that arise in executing home energy upgrade market delivery approaches, as identified through research conducted by the U.S. Department of Energy's (DOE) Building America program. This information will be used to provide guidance for new research necessary to enable the success of the approaches. Investigation for this report was conducted via publications related to home energy upgrade market delivery approaches, and a series of interviews with subject matter experts (contractors, consultants, program managers, manufacturers, trade organization representatives, and real estate agents). These experts specified technical barriers and gaps, and offered suggestions for how the technical community might address them. The potential benefits of home energy upgrades are many and varied: reduced energy use and costs; improved comfort, durability, and safety; increased property value; and job creation. Nevertheless, home energy upgrades do not comprise a large part of the overall home improvement market. Residential energy efficiency is the most complex climate intervention option to deliver because the market failures are many and transaction costs are high (Climate Change Capital 2009). The key reasons that energy efficiency investment is not being delivered are: (1) The opportunity is highly fragmented; and (2) The energy efficiency assets are nonstatus, low-visibility investments that are not properly valued. There are significant barriers to mobilizing the investment in home energy upgrades, including the 'hassle factor' (the time and effort required to identify and secure improvement works), access to financing, and the

  6. Monitoring parameters of technical condition and safety of aircraft using control charts

    Directory of Open Access Journals (Sweden)

    В.І. Чепіженко

    2007-03-01

    Full Text Available  The opportunity of control cards use for monitoring of a technical condition parameters and reliability of aviation techniques is considered at its operation on a technical condition.

  7. Technical basis for the aboveground structure failure and associated represented hazardous conditions

    International Nuclear Information System (INIS)

    GOETZ, T.G.

    2003-01-01

    This technical basis document describes the risk binning process and the technical basis for assigning risk bins for the aboveground structure failure representative accident and associated represented hazardous conditions. This document was developed to support the documented safety analysis

  8. 43 CFR 418.28 - Conditions of delivery.

    Science.gov (United States)

    2010-10-01

    ... particulars including the known or estimated location and amounts; (3) The amount will not be included as a valid headgate delivery for purposes of computing the Project efficiency and resultant incentive credit... treated directly as a debit to Lahontan storage in the same manner as an efficiency debit. (b) District...

  9. Adaptation of non-technical skills behavioural markers for delivery room simulation.

    Science.gov (United States)

    Bracco, Fabrizio; Masini, Michele; De Tonetti, Gabriele; Brogioni, Francesca; Amidani, Arianna; Monichino, Sara; Maltoni, Alessandra; Dato, Andrea; Grattarola, Claudia; Cordone, Massimo; Torre, Giancarlo; Launo, Claudio; Chiorri, Carlo; Celleno, Danilo

    2017-03-17

    Simulation in healthcare has proved to be a useful method in improving skills and increasing the safety of clinical operations. The debriefing session, after the simulated scenario, is the core of the simulation, since it allows participants to integrate the experience with the theoretical frameworks and the procedural guidelines. There is consistent evidence for the relevance of non-technical skills (NTS) for the safe and efficient accomplishment of operations. However, the observation, assessment and feedback on these skills is particularly complex, because the process needs expert observers and the feedback is often provided in judgmental and ineffective ways. The aim of this study was therefore to develop and test a set of observation and rating forms for the NTS behavioural markers of multi-professional teams involved in delivery room emergency simulations (MINTS-DR, Multi-professional Inventory for Non-Technical Skills in the Delivery Room). The MINTS-DR was developed by adapting the existing tools and, when needed, by designing new tools according to the literature. We followed a bottom-up process accompanied by interviews and co-design between practitioners and psychology experts. The forms were specific for anaesthetists, gynaecologists, nurses/midwives, assistants, plus a global team assessment tool. We administered the tools in five editions of a simulation training course that involved 48 practitioners. Ratings on usability and usefulness were collected. The mean ratings of the usability and usefulness of the tools were not statistically different to or higher than 4 on a 5-point rating scale. In either case no significant differences were found across professional categories. The MINTS-DR is quick and easy to administer. It is judged to be a useful asset in maximising the learning experience that is provided by the simulation.

  10. A conservation ontology and knowledge base to support delivery of technical assistance to agricultural producers in the united states

    Science.gov (United States)

    Information systems supporting the delivery of conservation technical assistance by the United States Department of Agriculture (USDA) to agricultural producers on working lands have become increasingly complex over the past 25 years. They are constrained by inconsistent coordination of domain knowl...

  11. Non-technical skills for obstetricians conducting forceps and vacuum deliveries: qualitative analysis by interviews and video recordings.

    Science.gov (United States)

    Bahl, Rachna; Murphy, Deirdre J; Strachan, Bryony

    2010-06-01

    Non-technical skills are cognitive and social skills required in an operational task. These skills have been identified and taught in the surgical domain but are of particular relevance to obstetrics where the patient is awake, the partner is present and the clinical circumstances are acute and often stressful. The aim of this study was to define the non-technical skills of an operative vaginal delivery (forceps or vacuum) to facilitate transfer of skills from expert obstetricians to trainee obstetricians. Qualitative study using interviews and video recordings. The study was conducted at two university teaching hospitals (St. Michael's Hospital, Bristol and Ninewells Hospital, Dundee). Participants included 10 obstetricians and eight midwives identified as experts in conducting or supporting operative vaginal deliveries. Semi-structured interviews were carried out using routine clinical scenarios. The experts were also video recorded conducting forceps and vacuum deliveries in a simulation setting. The interviews and video recordings were transcribed verbatim and analysed using thematic coding. The anonymised data were independently coded by the three researchers and then compared for consistency of interpretation. The experts reviewed the coded data for respondent validation and clarification. The themes that emerged were used to identify the non-technical skills required for conducting an operative vaginal delivery. The final skills list was classified into seven main categories. Four categories (situational awareness, decision making, task management, and team work and communication) were similar to the categories identified in surgery. Three further categories unique to obstetrics were also identified (professional relationship with the woman, maintaining professional behaviour and cross-monitoring of performance). This explicitly defined skills taxonomy could aid trainees' understanding of the non-technical skills to be considered when conducting an operative

  12. Internal design of technical systems under conditions of uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Krasnoshchekov, P S; Morozov, V V; Fedorov, V V

    1982-03-01

    An investigation is made of a model of internal design of a complex technical system in the presence of uncertain factors. The influence of an opponent on the design is examined. The concepts of hierarchical and balanced compatibility between the criteria of the designer, the opponent and the segregations functions are introduced and studied. The connection between the approach proposed and the methods of artificial intelligence is discussed. 5 references.

  13. Technical potential of evaporative cooling in Danish and European condition

    DEFF Research Database (Denmark)

    Pomianowski, Michal Zbigniew; Andersen, Christian Hede; Heiselberg, Per Kvols

    2015-01-01

    Evaporative cooling is a very interesting high temperature cooling solution that has potential to save energy comparing to refrigerant cooling systems and at the same time provide more cooling reliability than mechanical or natural ventilation system without cooling. Technical cooling potential...... of 5 different evaporative systems integrated in the ventilation system is investigated in this article. Annual analysis is conducted based on hourly weather data for 15 cities located in Denmark and 123 European cities. Investigated systems are direct, indirect, combinations of direct and indirect...

  14. Technical bio-oils. Fundamentals - products - framework conditions; Technische Biooele. Grundlagen - Produkte - Rahmenbedingungen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-27

    The Fachagentur Nachwachsende Rohstoffe e.V. (Guelzow-Pruezen, Federal Republic of Germany) and the Federal Ministry of Food, Agriculture and Consumer Protection (Bonn, Federal Republic of Germany) report on technical bio-oils. The contribution under consideration consists of the following chapters: Fundamentals, technical properties, applications, environmental aspects, legal framework conditions, funding measures; market of biological lubricants, economic operation with biological lubricants.

  15. Mode of delivery has an independent impact on neonatal condition at birth.

    Science.gov (United States)

    Prior, Tomas; Kumar, Sailesh

    2014-10-01

    Current intra-partum monitoring techniques are often criticized for their poor specificity, with their performance frequently evaluated using measures of the neonatal condition at birth as a surrogate marker for intra-partum fetal compromise. However, these measures may potentially be influenced by a multitude of other factors, including the mode of delivery itself. This study aimed to investigate the impact of mode of delivery on neonatal condition at birth. This prospective observational study, undertaken at a tertiary referral maternity unit in London, UK, included 604 'low risk' women recruited prior to delivery. Commonly assessed neonatal outcome variables (Apgar score at 1 and 5min, umbilical artery pH and base excess, neonatal unit admission, and a composite neonatal outcome score) were used to compare the condition at birth between babies born by different modes of delivery, using one-way ANOVA and chi-squared testing. Infants born by instrumental delivery for presumed fetal compromise had the poorest condition at birth (mean composite score=1.20), whereas those born by Cesarean section for presumed fetal compromise had a better condition at birth (mean composite score=0.64) (p=surrogate marker of intra-partum fetal compromise. When evaluating the efficacy of intra-partum monitoring techniques, the isolated use of Apgar scores, umbilical artery acidosis and neonatal unit admission should be discouraged. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  16. Tools to support important technical decisions during accident conditions

    International Nuclear Information System (INIS)

    Tenschert, J.; Bergiers, C.

    2008-01-01

    To handle design basis and beyond design basis accidents with intact reactor core, Nuclear Power Plants are using Emergency Operating Procedures (EOP) that they may have developed based on the generic Westinghouse Emergency Response Guidelines. Even though the EOPs are very directive, some questions are left to external support, i.e. to a team of persons constituting the so-called Technical Support Center (TSC). The Pressurized Water Reactor Owner Group (PWROG, previously Westinghouse Owner Group, WOG) has developed a TSC manual to support this group in their decision making process. Because of the specific and particular design of the Beznau NPP (KKB) Safety Systems, development of a plant-specific TSC manual required a lot of additions compared to the generic material. This plant-specific TSC manual is a helpful tool for the Site Emergency Director (SED) of the KKB to better evaluate issues and potential concerns arising while executing the EOPs. The majority of considered issues are relevant for beyond design basis accidents and external events. (orig.)

  17. Technical guide for monitoring selected conditions related to wilderness character

    Science.gov (United States)

    Peter Landres; Steve Boutcher; Liese Dean; Troy Hall; Tamara Blett; Terry Carlson; Ann Mebane; Carol Hardy; Susan Rinehart; Linda Merigliano; David N. Cole; Andy Leach; Pam Wright; Deb Bumpus

    2009-01-01

    The purpose of monitoring wilderness character is to improve wilderness stewardship by providing managers a tool to assess how selected actions and conditions related to wilderness character are changing over time. Wilderness character monitoring provides information to help answer two key questions about wilderness character and wilderness stewardship: 1. How is...

  18. Methods of monitoring the technical condition of the braking system of an autonomous vehicle during operation

    Science.gov (United States)

    Revin, A.; Dygalo, V.; Boyko, G.; Lyaschenko, M.; Dygalo, L.

    2018-02-01

    Possibilities of diagnosing of a technical condition of braking system of the autonomous vehicles with automated modules while in service are considered. The concept of sharing of onboard means and stands for diagnosing is presented.

  19. Identification of Technical Requirement for Improving Quality of Local Online Food Delivery Service in Yogyakarta

    OpenAIRE

    Elvandari, , Cecilia Desvita Ratna; Sukartiko, Anggoro Cahyo; Nugrahini, Arita Dewi

    2017-01-01

    Increased internet usage and fast-paced consumer’s demands have created business opportunities, including online food delivery services. However, competition with similar national-scale businesses allegedly contributed to the decline in the number of XYZ company orders, one of the food-delivery service providers in Yogyakarta. Therefore, this study aimed to identify the need’s attributes of the daring food delivery service consumers, to find out the service-quality satisfaction level, and to ...

  20. The analytical solution for drug delivery system with nonhomogeneous moving boundary condition

    Science.gov (United States)

    Saudi, Muhamad Hakimi; Mahali, Shalela Mohd; Harun, Fatimah Noor

    2017-08-01

    This paper discusses the development and the analytical solution of a mathematical model based on drug release system from a swelling delivery device. The mathematical model is represented by a one-dimensional advection-diffusion equation with nonhomogeneous moving boundary condition. The solution procedures consist of three major steps. Firstly, the application of steady state solution method, which is used to transform the nonhomogeneous moving boundary condition to homogeneous boundary condition. Secondly, the application of the Landau transformation technique that gives a significant impact in removing the advection term in the system of equation and transforming the moving boundary condition to a fixed boundary condition. Thirdly, the used of separation of variables method to find the analytical solution for the resulted initial boundary value problem. The results show that the swelling rate of delivery device and drug release rate is influenced by value of growth factor r.

  1. Evaluation of the technical condition of medium-sized boilers

    Directory of Open Access Journals (Sweden)

    Lošák Pavel

    2018-01-01

    Full Text Available The recent trend in the steam and electricity production has been both to increase the efficiency of the facility and to keep tightening legislation concerning emission limits. The lifetime of energy equipment is greatly influenced by the operating temperature, pressure and operating characteristics. The new conditions lead the operator to more often changes of these parameters, which has negative influence to the facility in terms of service life. Precise knowledge of the facility being operated and the ability to predict the residual life of its key parts in time is therefore necessary. A new methodology for determining the residual life and evaluating problematic situations of medium size boilers was developed at Brno University of Technology. Its approaches and advantages will be presented in this paper. The methodology provides the user with approaches for the lifetime evaluation of an equipment as a whole, based on detailed knowledge of the equipment being investigated and the ongoing damage. Additionally, if the equipment is continuously evaluated, it is possible to extend the inspection interval or to achieve a significantly higher lifetime of the entire equipment, thereby reducing the economic cost. If defined criteria are met, the methodology also allows inclusion of FEM and CFD simulations for achieving higher relevance of the results.

  2. Disparities in Chronic Conditions Among Women Hospitalized for Delivery in the United States, 2005-2014.

    Science.gov (United States)

    Admon, Lindsay K; Winkelman, Tyler N A; Moniz, Michelle H; Davis, Matthew M; Heisler, Michele; Dalton, Vanessa K

    2017-12-01

    To estimate trends in the prevalence and socioeconomic distribution of chronic conditions among women hospitalized for obstetric delivery in the United States. A retrospective, serial cross-sectional analysis was conducted using 2005-2014 data from the National Inpatient Sample. We estimated the prevalence of eight common, chronic conditions, each associated with obstetric morbidity and mortality, among all childbearing women and then across socioeconomic predictors of obstetric outcomes. Differences over time were measured and compared across rural and urban residence, income, and payer subgroups for each condition. We identified 8,193,707 delivery hospitalizations, representing 39,273,417 delivery hospitalizations occurring nationally between 2005 and 2014. Identification of at least one chronic condition increased significantly between 2005-2006 and 2013-2014 (66.9 per 1,000 delivery hospitalizations in 2005-2006 compared with 91.8 per 1,000 delivery hospitalizations in 2013-2014). The prevalence of multiple chronic conditions also increased during the study period, from 4.7 (95% CI 4.2-5.2) to 8.1 (95% CI 7.8-8.4) per 1,000 delivery hospitalizations between 2005-2006 and 2013-2014. Chronic respiratory disease, chronic hypertension, substance use disorders, and pre-existing diabetes were the disorders with the greatest increases in prevalence over time. Increasing disparities over time were identified across all socioeconomic subgroups analyzed including rural compared with urban residence, income, and payer. Key areas of concern include the rate at which substance use disorders rose among rural women and the disproportionate burden of each condition among women from the lowest income communities and among women with Medicaid as their primary payer. Between 2005-2006 and 2013-2014, the prevalence of chronic conditions increased across all segments of the childbearing population. Widening disparities were identified over time with key areas of concern including

  3. Voluntary medical male circumcision scale-up in Nyanza, Kenya: evaluating technical efficiency and productivity of service delivery.

    Science.gov (United States)

    Omondi Aduda, Dickens S; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

    2015-01-01

    Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya's context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350-5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959-4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of

  4. Voluntary Medical Male Circumcision Scale-Up in Nyanza, Kenya: Evaluating Technical Efficiency and Productivity of Service Delivery

    Science.gov (United States)

    Omondi Aduda, Dickens S.; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

    2015-01-01

    Background Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya’s context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. Objective To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Design Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Results Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350–5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959–4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Conclusions Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings

  5. River Protection Project waste feed delivery program technical performance measurement assessment plan

    International Nuclear Information System (INIS)

    O'TOOLE, S.M.

    1999-01-01

    This plan establishes a formal technical performance-monitoring program. Technical performance is assessed by establishing requirements based performance goals at the beginning of a program and routinely evaluating progress in meeting these goals at predetermined milestones throughout the project life cycle

  6. Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates

    OpenAIRE

    Samaranch, Lluis; Bringas, John; Pivirotto, Philip; Sebastian, Waldy San; Forsayeth, John; Bankiewicz, Krystof

    2015-01-01

    Accessing cerebrospinal fluid (CSF) from the craniocervical junction through the posterior atlanto-occipital membrane via cerebellomedullary injection (also known as cisternal puncture or cisterna magna injection) has become a standard procedure in preclinical studies. Such delivery provides broader coverage to the central and peripheral nervous system unlike local parenchymal delivery alone. As a clinical application, this approach offers a more reliable method for neurological gene replacem...

  7. The Impact of Ict on Business Models for Delivery Of ConsultancyServices - The Case Of Technical Engineering

    DEFF Research Database (Denmark)

    Falch, Morten; Nicolajsen, Hanne Westh

    2009-01-01

    This paper analyses the impact of the use of ICT in production and delivery of technical engineering consultancy services on business structures with regard to industry convergence and transaction costs. The paper takes an empirical study on the introduction of 3D-modelling tools in the building...... section in a Scandinavian engineering consultancy firm as its point of departure. The discussion identifies three different structural aspects, which all are affected by the use of ICT: Internationalisation vs. Local markets, Outsourcing vs. Structural integration, and Division of work between actors...

  8. Technical Note: Using experimentally determined proton spot scanning timing parameters to accurately model beam delivery time.

    Science.gov (United States)

    Shen, Jiajian; Tryggestad, Erik; Younkin, James E; Keole, Sameer R; Furutani, Keith M; Kang, Yixiu; Herman, Michael G; Bues, Martin

    2017-10-01

    To accurately model the beam delivery time (BDT) for a synchrotron-based proton spot scanning system using experimentally determined beam parameters. A model to simulate the proton spot delivery sequences was constructed, and BDT was calculated by summing times for layer switch, spot switch, and spot delivery. Test plans were designed to isolate and quantify the relevant beam parameters in the operation cycle of the proton beam therapy delivery system. These parameters included the layer switch time, magnet preparation and verification time, average beam scanning speeds in x- and y-directions, proton spill rate, and maximum charge and maximum extraction time for each spill. The experimentally determined parameters, as well as the nominal values initially provided by the vendor, served as inputs to the model to predict BDTs for 602 clinical proton beam deliveries. The calculated BDTs (T BDT ) were compared with the BDTs recorded in the treatment delivery log files (T Log ): ∆t = T Log -T BDT . The experimentally determined average layer switch time for all 97 energies was 1.91 s (ranging from 1.9 to 2.0 s for beam energies from 71.3 to 228.8 MeV), average magnet preparation and verification time was 1.93 ms, the average scanning speeds were 5.9 m/s in x-direction and 19.3 m/s in y-direction, the proton spill rate was 8.7 MU/s, and the maximum proton charge available for one acceleration is 2.0 ± 0.4 nC. Some of the measured parameters differed from the nominal values provided by the vendor. The calculated BDTs using experimentally determined parameters matched the recorded BDTs of 602 beam deliveries (∆t = -0.49 ± 1.44 s), which were significantly more accurate than BDTs calculated using nominal timing parameters (∆t = -7.48 ± 6.97 s). An accurate model for BDT prediction was achieved by using the experimentally determined proton beam therapy delivery parameters, which may be useful in modeling the interplay effect and patient throughput. The model may

  9. Coordination and safety procedures for mail delivery on roadways without shoulders : technical report.

    Science.gov (United States)

    2009-08-01

    This research utilized interviews, focus groups, and surveys of U.S. Postal Service (USPS) and Texas Department of Transportation (TxDOT) employees to determine safety and coordination issues related to mail delivery on rural, two-lane highways witho...

  10. Determination of dynamic performance of freight cars taking into account technical condition of side bearers

    Directory of Open Access Journals (Sweden)

    S.Myamlin

    2013-02-01

    Full Text Available Purpose. The railway transport plays an important role in social and economic life of the country and carries out the large containment of transportation activities. The transport industry should migrate towards innovation changes and increase its significance as an important transit subsystem on the way of renovation of both the infrastructure and the strategy of all transportation process components including the interaction with other transport modes. At present the life sets strategic challenges for the railway branch, and the basic goals among them are as follows: high-speed train traffic development, increase of the weight of freight trains, new rolling stock development etc. Due to the urgency of this subject, the researchers should cope with the task devoted to one of aspects of improving the freight transportation efficiency, namely to the study of effects of various factors and characteristics of technical conditions of the freight cars running gears (which are unavoidable to arise during operation on their basic dynamic indices. The deviations of technical conditions of running gears from the normal state of the wedge system of bogie swing suspension also play an important role among them. The purpose of the paper is to investigate the influence of different factors of the technical conditions of freight car running gears (size deviation in both the bearers and the wedge system during operation on their basic indices – coefficients of horizontal and vertical dynamics, vehicle body acceleration, frame strength, and derailment stability coefficient. Methodology. The study was conducted by numerical integration and mathematical modeling of the freight car dynamic loading using the software package “Dynamics of Rail Vehicles” (“DYNRAIL”. Findings. As a result of the research for freight car dynamic coefficients determination taking into account technical conditions of the side bearers, the dependencies of the basic freight cars

  11. Technical quality of delivery care in private- and public-sector health facilities in Enugu and Lagos States, Nigeria.

    Science.gov (United States)

    Hirose, Atsumi; Yisa, Ibrahim O; Aminu, Amina; Afolabi, Nathanael; Olasunmbo, Makinde; Oluka, George; Muhammad, Khalilu; Hussein, Julia

    2018-06-01

    Private-sector providers are increasingly being recognized as important contributors to the delivery of healthcare. Countries with high disease burdens and limited public-sector resources are considering using the private sector to achieve universal health coverage. However, evidence for the technical quality of private-sector care is lacking. This study assesses the technical quality of maternal healthcare during delivery in public- and private-sector facilities in resource-limited settings, from a systems and programmatic perspective. A summary index (the skilled attendance index, SAI), was used. Two-staged cluster sampling with stratification was used to select representative samples of case records in public- and private-sector facilities in Enugu and Lagos States, Nigeria. Information to assess criteria was extracted, and the SAI calculated. Linear regression models examined the relationship between SAI and the private and public sectors, controlling for confounders. The median SAI was 54.8% in Enugu and 85.7% in Lagos. The private for-profit sector's SAI was lower than and the private not-for-profit sector's SAI was higher than the public sector in Enugu [coefficient = -3.6 (P = 0.018) and 12.6 (P private for-profit sector's SAI was higher and the private not-for-profit sector's SAI was lower than the public sector [3.71 (P = 0.005) and -3.92 (P private for-profit providers' care was poorer than public providers where the public provision of care was weak, while private for-profit facilities provided better technical quality care than public facilities where the public sector was strong and there was a relatively strong regulatory body. Our findings raise important considerations relating to the quality of maternity care, the public-private mix and needs for regulation in global efforts to achieve universal healthcare.

  12. The methods for diagnostic of the technical condition of vehicles employing high precise satellite data

    Directory of Open Access Journals (Sweden)

    Anatoliy KULIK

    2014-03-01

    Full Text Available The paper presents a methodology for diagnostic of the technical condition of vehicle. The high accuracy of the actual trajectory of the transport aggregate (TA is provided by the use of local differential mode of global navigation satellite system (GNSS. Comparing the real and rational trajectories will determine the kinematic and dynamic characteristics of the car.

  13. PROJECT EVALUATION OF TECHNICAL CONDITION OF SHIP STRUCTURES WITH USE OF INFORMATION RETRIEVAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    Юлия Алексеевна КАЗИМИРЕНКО

    2015-06-01

    Full Text Available The mechanisms for evaluation of technical conditions of ship constructions were investigated and was developed a new specialized informational and search system for the collection, analysis and processing the defects of new materials during the designing, construction, operation of ships and floating structures for transportation of goods 1, 4, 6-8 classes of danger.

  14. Standards for Technological Literacy and STEM Education Delivery through Career and Technical Education Programs

    Science.gov (United States)

    Asunda, Paul A.

    2012-01-01

    At a minimum, employers rely on career and technical education (CTE) and workforce training systems to supply workers able to perform in their jobs. In CTE classes that seek to integrate science, technology, engineering, and mathematics (STEM) concepts, it falls to the instructors to design and sequence the learning experiences that will promote…

  15. Technical Improvement and Application of Hydrodynamic Gene Delivery in Study of Liver Diseases

    Directory of Open Access Journals (Sweden)

    Mei Huang

    2017-08-01

    Full Text Available Development of an safe and efficient in vivo gene delivery method is indispensable for molecular biology research and the progress in the following gene therapy. Over the past few years, hydrodynamic gene delivery (HGD with naked DNA has drawn increasing interest in both research and potential clinic applications due to its high efficiency and low risk in triggering immune responses and carcinogenesis in comparison to viral vectors. This method, involving intravenous injection (i.v. of massive DNA in a short duration, gives a transient but high in vivo gene expression especially in the liver of small animals. In addition to DNA, it has also been shown to deliver other substance such as RNA, proteins, synthetic small compounds and even viruses in vivo. Given its ability to robustly mimic in vivo hepatitis B virus (HBV production in liver, HGD has become a fundamental and important technology on HBV studies in our group and many other groups. Recently, there have been interesting reports about the applications and further improvement of this technology in other liver research. Here, we review the principle, safety, current application and development of hydrodynamic delivery in liver disease studies, and discuss its future prospects, clinical potential and challenges.

  16. CLASSIFICATION OF NEURAL NETWORK FOR TECHNICAL CONDITION OF TURBOFAN ENGINES BASED ON HYBRID ALGORITHM

    Directory of Open Access Journals (Sweden)

    Valentin Potapov

    2016-12-01

    Full Text Available Purpose: This work presents a method of diagnosing the technical condition of turbofan engines using hybrid neural network algorithm based on software developed for the analysis of data obtained in the aircraft life. Methods: allows the engine diagnostics with deep recognition to the structural assembly in the presence of single structural damage components of the engine running and the multifaceted damage. Results: of the optimization of neural network structure to solve the problems of evaluating technical state of the bypass turbofan engine, when used with genetic algorithms.

  17. Technical and scale efficiency in the delivery of child health services in Zambia: results from data envelopment analysis.

    Science.gov (United States)

    Achoki, Tom; Hovels, Anke; Masiye, Felix; Lesego, Abaleng; Leufkens, Hubert; Kinfu, Yohannes

    2017-01-05

    Despite tremendous efforts to scale up key maternal and child health interventions in Zambia, progress has not been uniform across the country. This raises fundamental health system performance questions that require further investigation. Our study investigates technical and scale efficiency (SE) in the delivery of maternal and child health services in the country. The study focused on all 72 health districts of Zambia. We compiled a district-level database comprising health outcomes (measured by the probability of survival to 5 years of age), health outputs (measured by coverage of key health interventions) and a set of health system inputs, namely, financial resources and human resources for health, for the year 2010. We used data envelopment analysis to assess the performance of subnational units across Zambia with respect to technical and SE, controlling for environmental factors that are beyond the control of health system decision makers. Nationally, average technical efficiency with respect to improving child survival was 61.5% (95% CI 58.2% to 64.8%), which suggests that there is a huge inefficiency in resource use in the country and the potential to expand services without injecting additional resources into the system. Districts that were more urbanised and had a higher proportion of educated women were more technically efficient. Improved cooking methods and donor funding had no significant effect on efficiency. With the pressing need to accelerate progress in population health, decision makers must seek efficient ways to deliver services to achieve universal health coverage. Understanding the factors that drive performance and seeking ways to enhance efficiency offer a practical pathway through which low-income countries could improve population health without necessarily seeking additional resources. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  18. Obstetric Outcomes and Delivery-Related Health Care Utilization and Costs Among Pregnant Women With Multiple Chronic Conditions

    Science.gov (United States)

    Winkelman, Tyler N. A.; Heisler, Michele; Dalton, Vanessa K.

    2018-01-01

    Our objective was to measure obstetric outcomes and delivery-related health care utilization and costs among pregnant women with multiple chronic conditions. We used 2013–2014 data from the National Inpatient Sample to measure obstetric outcomes and delivery-related health care utilization and costs among women with no chronic conditions, 1 chronic condition, and multiple chronic conditions. Women with multiple chronic conditions were at significantly higher risk than women with 1 chronic condition or no chronic conditions across all outcomes measured. High-value strategies are needed to improve birth outcomes among vulnerable mothers and their infants. PMID:29420168

  19. A meta-analysis of motivational interviewing process: Technical, relational, and conditional process models of change.

    Science.gov (United States)

    Magill, Molly; Apodaca, Timothy R; Borsari, Brian; Gaume, Jacques; Hoadley, Ariel; Gordon, Rebecca E F; Tonigan, J Scott; Moyers, Theresa

    2018-02-01

    In the present meta-analysis, we test the technical and relational hypotheses of Motivational Interviewing (MI) efficacy. We also propose an a priori conditional process model where heterogeneity of technical path effect sizes should be explained by interpersonal/relational (i.e., empathy, MI Spirit) and intrapersonal (i.e., client treatment seeking status) moderators. A systematic review identified k = 58 reports, describing 36 primary studies and 40 effect sizes (N = 3,025 participants). Statistical methods calculated the inverse variance-weighted pooled correlation coefficient for the therapist to client and the client to outcome paths across multiple target behaviors (i.e., alcohol use, other drug use, other behavior change). Therapist MI-consistent skills were correlated with more client change talk (r = .55, p technical hypothesis was supported. Specifically, proportion MI consistency was related to higher proportion change talk (r = .11, p = .004) and higher proportion change talk was related to reductions in risk behavior at follow up (r = -.16, p technical hypothesis path effect sizes was partially explained by inter- and intrapersonal moderators. This meta-analysis provides additional support for the technical hypothesis of MI efficacy; future research on the relational hypothesis should occur in the field rather than in the context of clinical trials. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  20. Is preterm delivery still related to physical working conditions in pregnancy?

    OpenAIRE

    Saurel-Cubizolles, M J; Subtil, D; Kaminski, M

    1991-01-01

    STUDY OBJECTIVE--The aim was to determine the relationship between working conditions during pregnancy, women's occupation, and preterm birth. DESIGN--This was a retrospective survey. SETTING--The study was carried out in four public maternity units in France in 1987 and 1988. SUBJECTS--1949 women were interviewed after the delivery during their stay in hospital. Of these, 1002 held a job during pregnancy, but this report is confined to 875 women who had a single live birth and who had worked...

  1. The Influence of the Technical Condition of a Building on the Property’s Market Value

    Directory of Open Access Journals (Sweden)

    Ziembicka Beata

    2016-12-01

    Full Text Available The housed property’s market value is influenced by a set of characteristic qualities, among which is the technical condition of a building. The aim of this paper is to study the influence of the technical condition of a building on the market price of the dwelling units, depending, among others, on the chosen method and the approach to the assessment of the housing wear degree. The analysis has been performed based on the estimation of the market value of an illustrative dwelling unit located in a building erected with the use of prefabricated large panel technology in selected variants. The study is based on data from the period between January and December 2012, which are related to the sale of rights to dwelling units from the secondary market. The information was obtained from a transactional database based on the Partner Data Exchange system with the Walor software.

  2. [Acoustic conditions in open plan office - Application of technical measures in a typical room].

    Science.gov (United States)

    Mikulski, Witold

    2018-03-09

    Noise in open plan offices should not exceed acceptable levels for the hearing protection. Its major negative effects on employees are nuisance and impediment in execution of work. Specific technical solutions should be introduced to provide proper acoustic conditions for work performance. Acoustic evaluation of a typical open plan office was presented in the article published in "Medycyna Pracy" 5/2016. None of the rooms meets all the criteria, therefore, in this article one of the rooms was chosen to apply different technical solutions to check the possibility of reaching proper acoustic conditions. Acoustic effectiveness of those solutions was verified by means of digital simulation. The model was checked by comparing the results of measurements and calculations before using simulation. The analyzis revealed that open plan offices supplemented with signals for masking speech signals can meet all the required criteria. It is relatively easy to reach proper reverberation time (i.e., sound absorption). It is more difficult to reach proper values of evaluation parameters determined from A-weighted sound pressure level (SPLA) of speech. The most difficult is to provide proper values of evaluation parameters determined from speech transmission index (STI). Finally, it is necessary (besides acoustic treatment) to use devices for speech masking. The study proved that it is technically possible to reach proper acoustic condition. Main causes of employees complaints in open plan office are inadequate acoustic work conditions. Therefore, it is necessary to apply specific technical solutions - not only sound absorbing suspended ceiling and high acoustic barriers, but also devices for speech masking. Med Pr 2018;69(2):153-165. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  3. Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges.

    Science.gov (United States)

    Wen, Ming Ming; El-Salamouni, Noha S; El-Refaie, Wessam M; Hazzah, Heba A; Ali, Mai M; Tosi, Giovanni; Farid, Ragwa M; Blanco-Prieto, Maria J; Billa, Nashiru; Hanafy, Amira S

    2017-01-10

    Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the rapidly growing elderly population in the developing world. The currently FDA approved drugs for the management of symptomatology of AD are marketed mainly as conventional oral medications. Due to their gastrointestinal side effects and lack of brain targeting, these drugs and dosage regiments hinder patient compliance and lead to treatment discontinuation. Nanotechnology-based drug delivery systems (NTDDS) administered by different routes can be considered as promising tools to improve patient compliance and achieve better therapeutic outcomes. Despite extensive research, literature screening revealed that clinical activities involving NTDDS application in research for AD are lagging compared to NTDDS for other diseases such as cancers. The industrial perspectives, processability, and cost/benefit ratio of using NTDDS for AD treatment are usually overlooked. Moreover, active and passive immunization against AD are by far the mostly studied alternative AD therapies because conventional oral drug therapy is not yielding satisfactorily results. NTDDS of approved drugs appear promising to transform this research from 'paper to clinic' and raise hope for AD sufferers and their caretakers. This review summarizes the recent studies conducted on NTDDS for AD treatment, with a primary focus on the industrial perspectives and processability. Additionally, it highlights the ongoing clinical trials for AD management. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Vectors of technical innovation delivery by small and medium Australian construction firms

    Directory of Open Access Journals (Sweden)

    Marie Hardie

    2016-09-01

    Full Text Available Long-established Schumpeterian theory on innovation assumes that significant innovations are generated by large companies with ample spare resources. The allocation of time and money to speculative endeavours with unclear outcomes has often been regarded as beyond the scope of small and medium-sized enterprises (SMEs. As a result, authorities sometimes advise SMEs to concentrate on the adoption of existing innovative products and processes rather than the generation of new creative ideas. Despite this traditional wisdom, some very capable individuals actively choose to participate in the SME sector because the relative absence of internal bureaucratic processes and the capacity for agile response to changing circumstances. Ten case studies of significant technical innovations generated within construction SMEs were examined in the light of common themes identified through a literature review. The case studies were classified according to existing taxonomies of innovation. Content analysis was used to map the identified themes against the published material about the innovations from patent applications, company websites, trade literature and industry magazines. The findings indicate that SME innovation stems from several distinct motivations. These drivers of innovation can be described vectors. They inspire innovative solutions but the generated innovations also drive development towards solutions for other, quite different problems.

  5. Information support of monitoring of technical condition of buildings in construction risk area

    Science.gov (United States)

    Skachkova, M. E.; Lepihina, O. Y.; Ignatova, V. V.

    2018-05-01

    The paper presents the results of the research devoted to the development of a model of information support of monitoring buildings technical condition; these buildings are located in the construction risk area. As a result of the visual and instrumental survey, as well as the analysis of existing approaches and techniques, attributive and cartographic databases have been created. These databases allow monitoring defects and damages of buildings located in a 30-meter risk area from the object under construction. The classification of structures and defects of these buildings under survey is presented. The functional capabilities of the developed model and the field of it practical applications are determined.

  6. A new positive pressure ventilation delivery system: its impact on lung ventilation studies that are technically inadequate or non diagnostic

    International Nuclear Information System (INIS)

    Bui, C.; Leiper, C.; Lee, K.; Saunders, C.; Dixson, H.; Elison, B.; Bennett, G.; Gibian, T.; Rutland, J.; Tse, V.; Elzein, H.; Babicheva, R.

    2000-01-01

    Full text: The objective of this study was to evaluate the efficacy and safety of an improved Positive Pressure Ventilation Delivery System (PVDS) in the investigation of Pulmonary Embolism (PE). The major component of PVDS is a commercially available, self-inflating 1.6L Hudson Resuscitator Bag, filled with either oxygen or air (if the patient has CO 2 retention), which is squeezed by the operator to push Technegas from the Technegas Generator Chamber to the patient via the Patient Administration Set synchronously with patient inspiration. 27 spontaneously breathing in-patients (12 males, 15 females, age range 64-89, 21 with chronic airflow limitation), whose conventional lung ventilation images were technically inadequate or non diagnostic, were re-scanned using PVDS within four days after the conventional ventilation study. Randomised blinded visual interpretation of conventional ventilation/perfusion scan vs. PVDS-assisted ventilation/perfusion scan was performed by consensus reading with two experienced observers. In conclusion PVDS was safe and well tolerated. PVDS improved the image quality of the lung ventilation scans in this cohort of patients. This technique has the potential to improve the accuracy of lung scanning in patients with severe lung disease. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

  7. Diagnostics of Technical Condition of Gear Units of Belt Conveyors for the Aggregate of Methods of Nondestructive Testing

    Science.gov (United States)

    Kuzin, Evgeny G.; Gerike, Boris L.; Drozdenko, Yuriy V.; Lupiy, Michael G.; Grigoryeva, Natalya V.

    2017-10-01

    The article reviews the issues of complex use of methods of technical diagnostics of gearboxes for belt conveyors, with the aim of creating an effective system of maintenance. The article is showing the results of the evaluation of the technical condition of the drives of belt conveyors based on vibration monitoring and thermal parameters, and analysis of lubricating oil.

  8. Evaluation of the technical feasibility of new conditioning matrices for long-lived radionuclides

    International Nuclear Information System (INIS)

    Deschanels, X.

    2004-01-01

    Several matrices have been selected for the conditioning of long-lived radioactive wastes: a compound made of a iodo-apatite core coated with a densified matrice of vanadium-phosphorus-lead apatite for iodine; the hollandite ceramic for cesium; the britholite, zirconolite, thorium phosphate diphosphate, and the monazite-brabantite solid solution for minor actinides; and a Nb-based metal alloy and phosphate or titanate-type ceramics for technetium. This report presents the results of the researches carried out between 2002-2004 during the technical feasibility step. The main points described are: - the behaviour of matrices under irradiation. These studies were performed thanks to an approach combining the characterization of natural analogues, the doping of matrices with short-lived radionuclides and the use of external irradiations; - the behaviour of these matrices with respect to water alteration; - the sensibility of these structures with respect to the incorporation of chemical impurities; - a package-process approach including the optimization of the process and preliminary studies about the package concept retained. These studies show that important work remains to be done to develop conditioning matrices suitable for iodine and technetium, while for cesium and minor actinides, the first steps of the technical feasibility are made. However, it remains impossible today to determine the structure having the best global behaviour. (J.S.)

  9. Behaviour of LWR core materials under accident conditions. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    1996-12-01

    At the invitation of the Government of the Russian Federation, following a proposal of the International Working Group on Water Reactor Fuel Performance and Technology, the IAEA convened a Technical Committee Meeting on Behaviour of LWR Core Materials Under Accident Conditions from 9 to 13 October 1995 in Dimitrovgrad to analyze and evaluate the behaviour of LWR core materials under accident conditions with special emphasis on severe accidents. In-vessel severe accidents phenomena were considered in detail, but specialized thermal hydraulic aspects as well as ex-vessel phenomena were outside the scope of the meeting. Forty participants representing eight countries attended the meeting. Twenty-three papers were presented and discussed during five sessions. Refs, figs, tabs

  10. Highly stable and degradable multifunctional microgel for self-regulated insulin delivery under physiological conditions

    Science.gov (United States)

    Zhang, Xinjie; Lü, Shaoyu; Gao, Chunmei; Chen, Chen; Zhang, Xuan; Liu, Mingzhu

    2013-06-01

    The response to glucose, pH and temperature, high drug loading capacity, self-regulated drug delivery and degradation in vivo are simultaneously probable by applying a multifunctional microgel under a rational design in a colloid chemistry method. Such multifunctional microgels are fabricated with N-isopropylacrylamide (NIPAAm), (2-dimethylamino)ethyl methacrylate (DMAEMA) and 3-acrylamidephenylboronic acid (AAPBA) through a precipitation emulsion method and cross-linked by reductive degradable N,N'-bis(arcyloyl)cystamine (BAC). This novel kind of microgel with a narrow size distribution (~250 nm) is suitable for diabetes because it can adapt to the surrounding medium of different glucose concentrations over a clinically relevant range (0-20 mM), control the release of preloaded insulin and is highly stable under physiological conditions (pH 7.4, 0.15 M NaCl, 37 °C). When synthesized multifunctional microgels regulate drug delivery, they gradually degrade as time passes and, as a result, show enhanced biocompatibility. This exhibits a new proof-of-concept for diabetes treatment that takes advantage of the properties of each building block from a multifunctional micro-object. These highly stable and versatile multifunctional microgels have the potential to be used for self-regulated therapy and monitoring of the response to treatment, or even simultaneous diagnosis as nanobiosensors.The response to glucose, pH and temperature, high drug loading capacity, self-regulated drug delivery and degradation in vivo are simultaneously probable by applying a multifunctional microgel under a rational design in a colloid chemistry method. Such multifunctional microgels are fabricated with N-isopropylacrylamide (NIPAAm), (2-dimethylamino)ethyl methacrylate (DMAEMA) and 3-acrylamidephenylboronic acid (AAPBA) through a precipitation emulsion method and cross-linked by reductive degradable N,N'-bis(arcyloyl)cystamine (BAC). This novel kind of microgel with a narrow size

  11. Technical evaluation on high aging, and performance conditions on long-term conservation program

    International Nuclear Information System (INIS)

    Yamashita, Atsushi

    2001-01-01

    In order to secure safety and safe operation of power plants, in every nuclear power plants, conservation actions based on preventive conservation are performed. They contain operative condition monitoring, patrolling inspection, and periodical tests on important systems and apparatus by operators under plant operation and condition monitoring by maintenance workers, and so on, and when finding out their abnormal conditions, their detailed survey is performed to adopt adequate countermeasures such as recovery, exchange, and so on. And, to equipments for nuclear power generation periodical conditions were obliged by legal examinations and by independent inspections. As a result of these conservation actions, even on a plant elapsed about 30 years since beginning of its operation it was thought that the plant was aged with elapsing time even if not recognizing any indication on its aged deterioration at that time. Therefore, for its concrete countermeasure, by supposing long-term operation of a plant with longer operation history, some technical evaluation on aged phenomena were carried out, to investigate on reflection of the obtained results to present conservation actions. Here were described on efforts on the high aging countermeasures, and performing conditions of long-term conservation in the Tsuruga Unit No. 1 Nuclear Power Station. (G.K.)

  12. Technical Condition of Earthen Dams at Nizhegorodskaya HPP After 60 Years of Operation

    Energy Technology Data Exchange (ETDEWEB)

    Kuznetsov, V. S., E-mail: kuznetsovVS@vniig.ru; Ladenko, S. Yu., E-mail: ladenko@yandex.ru [B. E. Vedeneev All-Russian Research Institute of Hydraulic Engineering (JSC) (Russian Federation)

    2016-03-15

    The complex of hydraulic engineering installations includes five earthen dams. All facilities are of Class I. The diagnostic parameters of dam operation and technical condition monitored via in-situ observation for seepage mode, seepage strength, settlement, static stability, etc. generally meet design assumptions and safety criteria. Despite individual defects and signs of “aging” identified over the period of earthen dam operation, these are currently in a satisfactory and operable state. The long, 60-year operating period of the dams with no serious overhauls or emergencies has demonstrated the high reliability of the facilities, the correctness of the design and technological solutions adopted and implemented in the construction, and the high professional level of their operation in close cooperation with science.

  13. Motives and perceptions regarding electronic nicotine delivery systems (ENDS) use among adults with mental health conditions.

    Science.gov (United States)

    Spears, Claire Adams; Jones, Dina M; Weaver, Scott R; Pechacek, Terry F; Eriksen, Michael P

    2018-05-01

    Smoking rates are disproportionately high among adults with mental health conditions (MHC), and recent research suggests that among former smokers, those with MHC are more likely to use electronic nicotine delivery systems (ENDS). This study investigated reasons for ENDS use and related risk perceptions among individuals with versus without MHC. Among adult current ENDS users (n=550), associations between self-reported MHC diagnoses and motives for ENDS use and ENDS risk perceptions were examined, stratified by smoking status. There were no significant associations between MHC status and ENDS motives or perceptions in the overall sample. However, current smokers with MHC indicated thinking more about how ENDS might improve their health, and former smokers with MHC reported thinking less about how ENDS might harm their health, compared to their counterparts without MHC. Former smokers with MHC rated several reasons for ENDS use (e.g., less harmful than regular cigarettes; to quit smoking; appealing flavors) as more important than did those without MHC. Current and former smokers with MHC may be especially optimistic about health benefits of ENDS. However, they might also be prone to health risks of continued ENDS use or concurrent use with traditional cigarettes. It will be important for public health messaging to provide this population with accurate information about benefits and risks of ENDS. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Use of Electronic Nicotine Delivery Systems among Adults with Mental Health Conditions, 2015

    Directory of Open Access Journals (Sweden)

    Claire Adams Spears

    2016-12-01

    Full Text Available Adults with mental health conditions (MHC are especially likely to smoke and experience tobacco-related health disparities. Individuals with MHC may also use electronic nicotine delivery devices (ENDS at disproportionately high rates. However, there is a relative dearth of knowledge regarding ENDS use among individuals with MHC. In a large representative sample of U.S. adults (n = 6051, associations between self-reported MHC diagnoses and ENDS use and susceptibility were examined, stratified by smoking status. Participants with MHC were approximately 1.5 times more likely to have used ENDS in their lifetime and almost twice as likely to currently use ENDS as those without MHC. MHC status was most strongly linked to higher ENDS use among former smokers, and former smokers with MHC were more likely to report using ENDS during past smoking quit attempts than those without MHC. Among participants who had not tried ENDS, former smokers with MHC were especially susceptible to future ENDS use. The potential advantage of ENDS for cessation purposes should be balanced with the risk of attracting former smokers with MHC to ENDS.

  15. Tidal volume delivery from ICU ventilators at BTPS conditions: a bench study.

    Science.gov (United States)

    Duchateau, Paul; Guérin, Claude

    2013-04-01

    Even though it is not a common practice, an external filter to the expiratory limb of the breathing circuit may protect the expiratory valve from water saturation in case of nebulization, or from the environment in case of lung infection with multi-drug-resistant micro-organisms or H1N1 influenza. We added an external filter to the expiratory limb and measured tidal volume (VT) from 6 ICU ventilators: 2 with built-in expiratory filter (Avea, Puritan Bennett 840), and 4 without (Engström Carestation, Evita XL, Evita V500, and Servo-i), set in volume controlled mode, at BTPS (body temperature and pressure saturated) condition, with a heated humidifier and a lung model (compliance 16 mL/cm H2O, resistance 20 cm H2O/L/s) placed inside a neonatal incubator. The temperature was targeted at 37°C for both the heated humidifier and the incubator. The setup was run continuously for 24 hours. In the latter 4 ICU ventilators, a Hygrobac or Sterivent S external filter was placed upstream from the expiratory valve for an additional 24-hour period for each. At the end of this period, VT was measured at 4 nominal VT values (300, 400, 500, and 800 mL) with a pneumotachograph. The volume error computed from the ratio of set to measured VT (% set VT) was the primary end point. In these warm and wet conditions, volume error averaged 96 ± 3% for Avea, 100 ± 7% for Puritan Bennett 840, 90 ± 2% for Evita XL, 100 ± 7% for Evita V500, 105 ± 2% for Servo-i, and 108 ± 4% for Engström Carestation (P ventilators for VT delivery, with further significant changes occurring after addition of a filter at the distal expiratory limb.

  16. Synchronized moving aperture radiation therapy (SMART): superimposing tumor motion on IMRT MLC leaf sequences under realistic delivery conditions

    International Nuclear Information System (INIS)

    Xu Jun; Papanikolaou, Nikos; Shi Chengyu; Jiang, Steve B

    2009-01-01

    Synchronized moving aperture radiation therapy (SMART) has been proposed to account for tumor motions during radiotherapy in prior work. The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator (DMLC) with the tumor motion induced by respiration. In this paper, a two-dimensional (2D) superimposing leaf sequencing method is presented for SMART. A leaf sequence optimization strategy was generated to assure the SMART delivery under realistic delivery conditions. The study of delivery performance using the Varian LINAC and the Millennium DMLC showed that clinical factors such as collimator angle, dose rate, initial phase and machine tolerance affect the delivery accuracy and efficiency. An in-house leaf sequencing software was developed to implement the 2D superimposing leaf sequencing method and optimize the motion-corrected leaf sequence under realistic clinical conditions. The analysis of dynamic log (Dynalog) files showed that optimization of the leaf sequence for various clinical factors can avoid beam hold-offs which break the synchronization of SMART and fail the SMART dose delivery. Through comparison between the simulated delivered fluence map and the planed fluence map, it was shown that the motion-corrected leaf sequence can greatly reduce the dose error.

  17. Condition monitoring using empirical models: technical review and prospects for nuclear applications

    International Nuclear Information System (INIS)

    Heo, Gyun Young

    2008-01-01

    The purpose of this paper is to extensively review the Condition Monitoring (CM) techniques using empirical models in an effort to reduce or eliminate unexpected downtimes in general industry, and to illustrate the feasibility of applying them to the nuclear industry. CM provides on-time warnings of system states to enable the optimal scheduling of maintenance and, ultimately, plant uptime is maximized. Currently, most maintenance processes tend to be either reactive, or part of scheduled, or preventive maintenance. Such maintenance is being increasingly reported as a poor practice for two reasons: first, the component does not necessarily require maintenance, thus the maintenance cost is wasted, and secondly, failure catalysts are introduced into properly working components, which is worse. This paper first summarizes the technical aspects of CM including state estimation and state monitoring. The mathematical background of CM is mature enough even for commercial use in the nuclear industry. Considering the current computational capabilities of CM, its application is not limited by technical difficulties, but by a lack of desire on the part of industry to implement it. For practical applications in the nuclear industry, it may be more important to clarify and quantify the negative impact of unexpected outcomes or failures in CM than it is to investigate its advantages. In other words, while issues regarding accuracy have been targeted to date, the concerns regarding robustness should now be concentrated on. Standardizing the anticipated failures and the possibly harsh operating conditions, and then evaluating the impact of the proposed CM under those conditions may be necessary. In order to make the CM techniques practical for the nuclear industry in the future, it is recommended that a prototype CM system be applied to a secondary system in which most of the components are non-safety grade. Recently, many activities to enhance the safety and efficiency of the

  18. A Question of Trust: Predictive Conditions for Adaptive and Technical Leadership in Educational Contexts

    Science.gov (United States)

    Daly, Alan J.; Chrispeels, Janet

    2008-01-01

    Recent studies have suggested that educational leaders enacting a balance of technical and adaptive leadership have an effect on increasing student achievement. Technical leadership focuses on problem-solving or first-order changes within existing structures and paradigms. Adaptive leadership involves deep or second-order changes that alter…

  19. Technical Needs for Enhancing Risk Monitors with Equipment Condition Assessment for Advanced Small Modular Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Coble, Jamie B.; Coles, Garill A.; Ramuhalli, Pradeep; Meyer, Ryan M.; Berglin, Eric J.; Wootan, David W.; Mitchell, Mark R.

    2013-04-04

    Advanced small modular reactors (aSMRs) can provide the United States with a safe, sustainable, and carbon-neutral energy source. The controllable day-to-day costs of aSMRs are expected to be dominated by operation and maintenance costs. Health and condition assessment coupled with online risk monitors can potentially enhance affordability of aSMRs through optimized operational planning and maintenance scheduling. Currently deployed risk monitors are an extension of probabilistic risk assessment (PRA). For complex engineered systems like nuclear power plants, PRA systematically combines event likelihoods and the probability of failure (POF) of key components, so that when combined with the magnitude of possible adverse consequences to determine risk. Traditional PRA uses population-based POF information to estimate the average plant risk over time. Currently, most nuclear power plants have a PRA that reflects the as-operated, as-modified plant; this model is updated periodically, typically once a year. Risk monitors expand on living PRA by incorporating changes in the day-by-day plant operation and configuration (e.g., changes in equipment availability, operating regime, environmental conditions). However, population-based POF (or population- and time-based POF) is still used to populate fault trees. Health monitoring techniques can be used to establish condition indicators and monitoring capabilities that indicate the component-specific POF at a desired point in time (or over a desired period), which can then be incorporated in the risk monitor to provide a more accurate estimate of the plant risk in different configurations. This is particularly important for active systems, structures, and components (SSCs) proposed for use in aSMR designs. These SSCs may differ significantly from those used in the operating fleet of light-water reactors (or even in LWR-based SMR designs). Additionally, the operating characteristics of aSMRs can present significantly different

  20. Weeks Island brine diffuser site study: baseline conditions and environmental assessment technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-12

    This technical report presents the results of a study conducted at two alternative brine diffuser sites (A and B) proposed for the Weeks Island salt dome, together with an analysis of the potential physical, chemical, and biological effects of brine disposal for this area of the Gulf of Mexico. Brine would result from either the leaching of salt domes to form or enlarge oil storage caverns, or the subsequent use of these caverns for crude oil storage in the Strategic Petroleum Reserve (SPR) program. Brine leached from the Weeks Island salt dome would be transported through a pipeline which would extend from the salt dome either 27 nautical miles (32 statute miles) for Site A, or 41 nautical miles (47 statute miles) for Site B, into Gulf waters. The brine would be discharged at these sites through an offshore diffuser at a sustained peak rate of 39 ft/sup 3//sec. The disposal of large quantities of brine in the Gulf could have a significant impact on the biology and water quality of the area. Physical and chemical measurements of the marine environment at Sites A and B were taken between September 1977 and July 1978 to correlate the existing environmental conditions with the estimated physical extent of tthe brine discharge as predicted by the MIT model (US Dept. of Commerce, 1977a). Measurements of wind, tide, waves, currents, and stratification (water column structure) were also obtained since the diffusion and dispersion of the brine plume are a function of the local circulation regime. These data were used to calculate both near- and far-field concentrations of brine, and may also be used in the design criteria for diffuser port configuration and verification of the plume model. Biological samples were taken to characterize the sites and to predict potential areas of impact with regard to the discharge. This sampling focused on benthic organisms and demersal fish. (DMC)

  1. Delivery of therapeutics for deep-seated ocular conditions - status quo.

    Science.gov (United States)

    Nguyen, Hubert; Eng, Shawn; Ngo, Thanh; Dass, Crispin R

    2018-04-19

    There is a need for research into designing effective pharmaceutical systems for delivering therapeutic drugs to the posterior of the eye for glaucoma-related pathology, macular degeneration, diabetic retinopathy, macular oedema, retinitis and choroiditis. Conventionally, eye drops have been extensively utilised for topical drug delivery to the anterior segment of the eye, but are less effective for delivery of therapeutics to the back of the eye due to significant barriers hampering drug penetration into the target intraocular tissue. This review explores some of the current and novel delivery systems employed to deliver therapeutics to the back of the eye such as those using liposomes, ocular implants, in situ gels, and nanoparticles, and how they can overcome some of these limitations. Issues such as blinking, precorneal fluid drainage, tear dilution and turnover, conjunctiva and nasal drug absorption, the corneal epithelium, vitreous drug clearance, and the blood-ocular barriers are reviewed and discussed. Further studies are needed to address their shortcomings such as drug compatibility and stability, economic viability and patient compliance. © 2018 Royal Pharmaceutical Society.

  2. Technical snow production in skiing areas: conditions, practice, monitoring and modelling. A case study in Mayrhofen/Austria

    Science.gov (United States)

    Strasser, Ulrich; Hanzer, Florian; Marke, Thomas; Rothleitner, Michael

    2017-04-01

    The production of technical snow today is a self-evident feature of modern alpine skiing resort management. Millions of Euros are invested every year for the technical infrastructure and its operation to produce a homogeneous and continuing snow cover on the skiing slopes for the winter season in almost every larger destination in the Alps. In Austria, skiing tourism is a significant factor of the national economic structure. We present the framing conditions of technical snow production in the mid-size skiing resort of Mayrhofen (Zillertal Alps/Austria, 136 km slopes, elevation range 630 - 2.500 m a.s.l.). Production conditions are defined by the availability of water, the planned date for the season opening, and the climatic conditions in the weeks before. By means of an adapted snow production strategy an attempt is made to ecologically and economically optimize the use of water and energy resources. Monitoring of the snow cover is supported by a network of low-cost sensors and mobile snow depth recordings. Finally, technical snow production is simulated with the spatially distributed, physically based hydroclimatological model AMUNDSEN. The model explicitly considers individual snow guns and distributes the produced snow along the slopes. The amount of simulated snow produced by each device is a function of its type, of actual wet-bulb temperature at the location, of ski area infrastructure (in terms of water supply and pumping capacity), and of snow demand.

  3. The Relationship of Repeated Technical Assistance Support Visits to the Delivery of Positive Health, Dignity, and Prevention (PHDP) Messages by Healthcare Providers in Mozambique: A Longitudinal Multilevel Analysis.

    Science.gov (United States)

    Gutin, Sarah A; Amico, K Rivet; Hunguana, Elsa; Munguambe, António Orlando; Rose, Carol Dawson

    Positive health, dignity, and prevention (PHDP) is Mozambique's strategy to engage clinicians in the delivery of prevention messages to their HIV-positive clients. This national implementation strategy uses provider trainings on offering key messages and focuses on intervening on 9 evidence-based risk reduction areas. We investigated the impact of longitudinal technical assistance (TA) as an addition to this basic training. We followed 153 healthcare providers in 5 Mozambican provinces over 6 months to evaluate the impact of on-site, observation-based TA on PHDP implementation. Longitudinal multilevel models were estimated to model change in PHDP message delivery over time among individual providers. With each additional TA visit, providers delivered about 1 additional PHDP message ( P < .001); clinicians and nonclinicians started at about the same baseline level, but clinicians improved more quickly ( P = .004). Message delivery varied by practice sector; maternal and child health sectors outperformed other sectors. Longitudinal TA helped reach the programmatic goals of the PHDP program in Mozambique.

  4. The dose received by patients during dental X-ray examination and the technical condition of radiological equipment.

    Science.gov (United States)

    Bekas, Marcin; Pachocki, Krzysztof A

    2013-01-01

    Implementation of X-ray dental examination is associated with the patients exposure to ionizing radation. The size of the exposure depends on the type of medical procedure, the technical condition of the X-ray unit and selected exposure conditions. The aim of this study was to determine the dose received by patients during dental X-ray examination and the assessment of the technical condition of medical equipment, The study included a total number of 79 dental X-ray units located in the region of Mazovia. The test methods for the assessment of the technical condition of dental X-ray units and measurement of radiation dose received by patients were based on the procedures elaborated in the Department of Radiation Hygiene and Radiobiology in the National Institute of Public Health - National Institute of Hygiene (Warszawa, Poland) accredited for the certification of compliance with PN-EN 17025. The research found that 69.6% fully meets the criteria set out in the Polish legislation regarding the safe use of ionizing radiation in medicine, while 30.4% did not meet some of them. A tenfold difference in the size of the dose received by patients during dental X-ray examinations was discovered. For example, during a radiography of the canine teeth of a child, the recorded entrance surface dose (ESD) ranged from 72.8 to 2430 microGy with the average value of 689.1 microGy. Cases where the dose reference level defined in Polish legislation of 5 mGy was exceeded were also found. CONCKUSIONS: It is essential to constantly monitor the situation regarding the technical condition of X-ray units which affects the size of the population's exposure to ionizing radiation as well as raising dentists' awareness about the effects of X-rays on the human body.

  5. ''Iodine delivery rate'' with catheterangiography under pressure conditions of hand injection

    International Nuclear Information System (INIS)

    Busch, H.P.; Stocker, K.P.

    1998-01-01

    Purpose: The aim of this study was to record the flow-rate and to calculate the 'iodine delivery rate' (IDR) of contrast media of various viscosities when the contrast media are injected by hand. Methods: Five different catheters for coronary angiography were tested with the injection system Medral Mark V Plus. Injections were performed with pressures of 100, 200 and 400 PSI. The contrast media examined were Imeron 350, Imeron 400, Omnipaque 350 and Ultravist 370. The IDR was calculated on the basis of the measured flow rate and the Iodine content of the contrast medium. Results: As was expected, the IDR was higher as the pressure increased. In addition to the iodine content the viscosity of the contrast medium is a very important factor for the IDR. At both 100 PSI and 200 PSI the increase of the IDR was higher with Imeron 350 than with Imeron 400. The comparison of contrast media with identical iodine contents but differing viscosities (Imeron 350, Omnipaque 350) clearly showed that the IDR depended on viscosity. Conclusion: The 'iodine delivery rate' is a decisive factor in the opacification of arterial vessels. Both iodine content and viscosity of a contrast medium are important for the IDR. Because of the low pressure at manual injection, contrast media with low viscosities should be used. A further possibility to increase the IDR is warming-up the contrast medium to body temperature. (orig.) [de

  6. Technical baseline description of high-level waste and low-activity waste feed mobilization and delivery

    International Nuclear Information System (INIS)

    Papp, I.G.

    1997-01-01

    This document is a compilation of information related to the high-level waste (HLW) and low-activity waste (LAW) feed staging, mobilization, and transfer/delivery issues. Information relevant to current Tank Waste Remediation System (TWRS) inventories and activities designed to feed the Phase I Privatization effort at the Hanford Site is included. Discussions on the higher level Phase II activities are offered for a perspective on the interfaces

  7. 20 CFR 662.430 - Under what conditions may One-Stop operators designated to operate in a One-Stop delivery system...

    Science.gov (United States)

    2010-04-01

    ... designated to operate in a One-Stop delivery system established prior to the enactment of WIA be designated... DESCRIPTION OF THE ONE-STOP SYSTEM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT One-Stop Operators § 662.430 Under what conditions may One-Stop operators designated to operate in a One-Stop delivery system...

  8. Framework conditions and requirements to ensure the technical functional safety of reprocessed medical devices.

    Science.gov (United States)

    Kraft, Marc

    2008-09-03

    Testing and restoring technical-functional safety is an essential part of medical device reprocessing. Technical functional tests have to be carried out on the medical device in the course of the validation of reprocessing procedures. These ensure (in addition to the hygiene tests) that the reprocessing procedure is suitable for the medical device. Functional tests are, however, also a part of reprocessing procedures. As a stage in the reprocessing, they ensure for the individual medical device that no damage or other changes limit the performance. When determining which technical-functional tests are to be carried out, the current technological standard has to be taken into account in the form of product-specific and process-oriented norms. Product-specific norms primarily define safety-relevant requirements. The risk management method described in DIN EN ISO 14971 is the basis for recognising hazards; the likelihood of such hazards arising can be minimised through additional technical-functional tests, which may not yet have been standardised. Risk management is part of a quality management system, which must be bindingly certified for manufacturers and processors of critical medical devices with particularly high processing demands by a body accredited by the competent authority.

  9. Effect of milk sample delivery methods and arrival conditions on bacterial contamination rates.

    Science.gov (United States)

    Dinsmore, R P; English, P B; Matthews, J C; Sears, P M

    1990-07-01

    A cross sectional study was performed of factors believed to contribute to the contamination of bovine milk sample cultures submitted to the Ithaca Regional Laboratory of the Quality Milk Promotion Services/New York State Mastitis Control. Of 871 samples entered in the study, 137 (15.7%) were contaminated. There were interactions between the sample source (veterinarian vs dairyman), delivery method, and time between sample collection and arrival at the laboratory. If only those samples collected and hand delivered by the dairyman within 1 day of collection were compared to a like subset of samples collected and hand delivered by veterinarians, no statistically significant differences in milk sample contamination rate (MSCR) were found. Samples were delivered to the laboratory by hand, US Postal Service, United Parcel Service, via the New York State College of Veterinary Medicine Diagnostic Laboratory, or Northeast Dairy Herd Improvement Association Courier. The MSCR was only 7.6% for hand delivered samples, while 26% of Postal Service samples were contaminated. These rates differed significantly from other delivery methods (P less than 0.0001). The USPS samples arrived a longer time after sampling than did samples sent by other routes, and time had a significant effect on MSCR (0 to 1 day, 8.9%; greater than 1 day, 25.9%; P less than 0.01). Samples packaged with ice packs sent by routes other than the Postal Service had a lower MSCR than those not packaged with ice packs, but ice packs did not reduce the MSCR for samples sent by the Postal Service.(ABSTRACT TRUNCATED AT 250 WORDS)

  10. Sediment delivery ratio in a small semi-arid watershed under conditions of low connectivity

    Directory of Open Access Journals (Sweden)

    Julio Cesar Neves dos Santos

    Full Text Available ABSTRACT The semi-arid region in the northeast of Brazil is characterised by rains of high intensity and short duration, with the processes of erosion being aggravated by an inappropriate land-use model. In this region, the lack of measured data for runoff and sediment yield increases the need to apply hydro-sedimentological models in estimating erosion, requiring knowledge of the actual sediment delivery ratio for the region. The aim of this study therefore, was to map soil erosion, making use of the Universal Soil Loss Equation (USLE, in the Iguatu Experimental Watershed (IEW. The mean annual sediment delivery ratio (SDR, and the SDR for individual events, was calculated from hydro-sedimentological measurements, contributing to an understanding of the processes of sediment propagation in the Brazilian semi-arid region, allowing identification of areas susceptible to water erosion. The IEW has an area of 16.74 km2 and is equipped with sensors for the continuous measurement of rainfall, flow and sediment yield. The mean annual SDR for the IEW was 0.37%. The SDR for individual rainfall events ranged from 0.08 to 1.67%, with an average of 0.68%. Among the main variables that influence the SDR for individual events is the magnitude of rainfall depth and antecedent soil moisture that can be better represented by the total antecedent precipitation of the previous 15 days. According to maps of soil loss, only 6.27% of the watershed presented losses beyond tolerable limits.

  11. Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

    Science.gov (United States)

    Tian, Chaorui; Yuan, Xueli; Bagley, Jessamyn; Blazar, Bruce R.; Sayegh, Mohamed H.; Iacomini, John

    2008-01-01

    The observation that bone marrow derived hematopoietic cells are potent inducers of tolerance has generated interest in trying to establish transplantation tolerance by inducing a state of hematopoietic chimerism through allogeneic bone marrow transplantation. However, this approach is associated with serious complications that limit its utility for tolerance induction. Here we describe the development of a novel approach that allows for tolerance induction without the need for an allogeneic bone marrow transplant by combining non-myeloablative host conditioning with delivery of donor alloantigen by adoptively transferred T cells. CBA/Ca mice were administered 2.5Gy whole body irradiation (WBI). The following day the mice received Kb disparate T cells from MHC class I transgenic CBK donor mice, as well as rapamycin on days 0–13 and anti-CD40L monoclonal antibody on days 0–5, 8,11 and 14 relative to T cell transfer. Mice treated using this approach were rendered specifically tolerant to CBK skin allografts through a mechanism involving central and peripheral deletion of alloreactive T cells. These data suggest robust tolerance can be established without the need for bone marrow transplantation using clinically relevant non-myeloablative conditioning combined with antigen delivery by T cells. PMID:18280792

  12. Economic-mathematical substantiation of optimizing the use of technical means, to perform tasks in conditions of uncertainty

    Directory of Open Access Journals (Sweden)

    I. V. Kuksova

    2017-01-01

    Full Text Available In this article a variant of the economic-mathematical substantiation of optimization approaches choice of tools for the survey of airfields, the mechanism of the use of multiple statistical criteria for optimality and usefulness of the decisions taken in this matter, when operating in conditions of uncertainty. Lately in the modern world in many socio-economic areas of human life quite often there are thematic challenges of managerial decision-making in a conflict environment and competition, when several in the General case, reasonable working actors perform collective decision-making, and the benefits of each depends not only on the chosen business strategies, but also from management decisions of other partners and the success of the experiments. Therefore, it is necessary to develop and substantiation of optimum variants of decision of choice of forces and means to perform tasks in conditions of uncertainty, that is also acceptable for military units. The actual problem currently is to optimize system control engineering-airfield security, the components of which perform their tasks under conditions of uncertainty. Analysis of opportunities of technical means (unmanned aerial vehicles shows that under the condition of equipping them with the appropriate equipment can be considered about the possibility of their use as part of a complex of technical means for inspection of airfields after the who enemy action in the runway. Therefore, the scientific goal in this article is to examine the possibilities of using technical means for inspection of airfield engineering and airfield services, and the aim of the study is using mathematical methods to justify the choice of the most effective means, from the point of view of economic cost of its introduction and use when performing tasks in conditions of uncertainty.

  13. Nagra technical report 14-02, geological basics - Dossier V - Hydro-geological conditions

    International Nuclear Information System (INIS)

    Traber, D.; Gautschi, A.; Marschall, P.; Becker, J.; Waber, N.

    2014-01-01

    This dossier is the fifth of a series of eight reports concerning the safety and technical aspects of locations for the disposal of radioactive wastes in Switzerland. Dossier V looks at hydro-geological considerations in North-Western Switzerland. Rock layers in the region and their hydrological properties are examined. Ground-water and deeper lying aquifers in the various rock formations are discussed. The specific hydrology in the proposed areas for nuclear waste depositories is looked at, including infiltration and exfiltration zones and gradients

  14. TECHNICAL AND ECONOMIC EVALUATION OF THE HARVEST OF EUCALYPTUS WITH FELLER-BUNCHER IN DIFFERENT OPERATING CONDITIONS

    Directory of Open Access Journals (Sweden)

    Danilo Simões

    2010-12-01

    Full Text Available This study aimed to technically and economically evaluate the Feller-buncher in different conditions of harvest in eucalyptus forests of second cut. The technical analysis included a study of time and movements by the method of continuous time, and operational performance was determined by volume in cubic meters of harvested wood. The economic analysis included the parameters of operational cost, harvest cost and energy consumption. The analysis of the data showed that the composition of main line harvesting and the arrangement of bundles of trees influenced operational performance. The average operational cost was US$ 86.26 per hour of actual work, which resulted in an average cost of forest harvesting of US$ 1.09 m-³.

  15. Technical and economical conditions of nuclear energy usage continuation in Lithuania

    International Nuclear Information System (INIS)

    Gylys, J.; Ziedelis, S.; Klevas, V.

    2005-01-01

    The main producer of electric energy in Lithuania is Ignalina NPP with its two RBMK-1500 type reactors. It covers up to 86% of total annual electricity production. The compulsory premature closure of Ignalina NPP due to the decision of EU authorities will decrease maximum power generating capacity to 3273 MW in the year 2010 (slump of 42% in respect to 5698 MW of the year 2000) and it will cause a complex of serious technical, economical, ecological, and social consequences. The most important ones for energy sector are the negative power balance and the shortage of power generating capacity which can emerge straight after closure of the second unit of Ignalina NPP. An attempt has been taken to prove, that the most realistic way for replacement of lost power generating capacities is the construction of new nuclear or combined cycle gas turbine power plants. The results of the comparative analysis of their effectiveness and competitiveness are presented in the paper. Estimating the basic prevailing technical and economical factors and three possible scenarios of economy growth, the changes of power balance and levelised cost of produced electricity are compared. It is demonstrated that a new modern nuclear power plant would be competitive and it would be even a more favourable option in respect to a combined cycle gas turbine power plant due to the relatively lower energy production cost, especially when estimating the possible future growth of price for fossil fuel. (authors)

  16. Electron Conditioning of Technical Aluminium Surfaces: Effect on the Secondary Electron Yield

    Energy Technology Data Exchange (ETDEWEB)

    Le Pimpec, F.

    2004-12-13

    The effect of electron conditioning on commercially aluminium alloys 1100 and 6063 were investigated. Contrary to the assumption that electron conditioning, if performed long enough, can reduce and stabilize the SEY to low values (< 1.3, value of many pure elements [1] ), the SEY of aluminium did not go lower than 1.8. In fact, it reincreases with continued electron exposure dose.

  17. Technical Aspects Regarding the Preservation of Dry Onions in Different Storage Conditions

    Directory of Open Access Journals (Sweden)

    Marian Vintila

    2014-11-01

    Full Text Available Research refers to the ability to maintain the quality of dry onions in different conditions of temperature, the three varieties used in experimentation (De Buzau, Daytona and Countach being stored after proper preparation at ambient temperature (+20…+22°C, refrigerated (+10…+12°C and cold conditions (+3…+5°C. Storage life, the level of weight (mass and decay losses and evolution of some chemical components determined from the 9 variants led to the conclusion that the best results were obtained by De Buzau variety for storage under ambient conditions and Daytona variety for storage under refrigerated and cold conditions. Moreover large differences between varieties and their behavior depending on storage conditions require choosing resistant cultivars and optimum storage temperatures according to destination and period of marketing or consumption.

  18. ELECTRICALLY CONDUCTIVE OF NANOCOMPOSITES FOR SYSTEMS DIAGNOSTICS OF THE ENVELOPE WALLS TECHNICAL CONDITION OF NPP

    Directory of Open Access Journals (Sweden)

    BOLSHAKOV V. I.

    2016-05-01

    Full Text Available Raising of the problem. Enveloped concrete wall type structures of localizing safety systems for restaint and localization of radioactive decay products or in the case of special natural or man-made impacts on the power unit is one of the most important components to ensure the safety of nuclear power. The promising direction for the development of the NPP technical system monitoring is to use conductive nanocomposites as primary elements of information. The purpose of the article is to review the theoretical background and experience in the conductive nanocomposites creating for diagnostics of localizing nuclear safety systems. Conclusions. A promising area for the development of diagnostic systems of localizing nuclear safety systems is the use of electrically conductive nanocomposites (conductive concrete - bethels, plasters, paint coatings. A mechanism for conductive nanocomposites creating is the use of the filler metal and carbon nanoparticles. As binders is promising to use nanocomposites of the mineral binders (cement and water glass.

  19. Test reference years - meteorological bases for the technical simulation of heating systems and air-conditioning systems

    International Nuclear Information System (INIS)

    Perl, J.

    1991-01-01

    For the FRG (western part) for 12 regions with different climate test reference years (TRY) have been established. The TRYs are used for the simulation of the thermal behaviour of buildings, of the operation of heating and space avc systems, lighting control, solar plants as well as of comparable technical systems. A TRY is a collection of hourly data of important meterological parameters over a whole year. The TRYs include 14 meteorological parameters for temperature, humidity, wind, short- and long-wave radiation, atmospheric pressure, precipitation and description of the weather at that time. A TRY is to correspond to the characteristic weather conditions of the TRY region. (orig.) [de

  20. Trout Creek, Oregon Watershed Assessment; Findings, Condition Evaluation and Action Opportunities, 2002 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Runyon, John

    2002-08-01

    The purpose of the assessment is to characterize historical and current watershed conditions in the Trout Creek Watershed. Information from the assessment is used to evaluate opportunities for improvements in watershed conditions, with particular reference to improvements in the aquatic environment. Existing information was used, to the extent practicable, to complete this work. The assessment will aid the Trout Creek Watershed Council in identifying opportunities and priorities for watershed restoration projects.

  1. Possibilities of Monitoring the Technical Condition of the Combustion Engine with Starter Load Current

    Directory of Open Access Journals (Sweden)

    Michal Jukl

    2014-01-01

    Full Text Available This article deals with the verification of relations between the electric current of engine starter and tightness of the combustion chamber and the possibility of its use for the evaluation of the state in terms of engine wear. Engine wear is closely related to the quality of fuel combustion and also with the amount of produced harmful emissions. On this basis, it would be possible to extend the technical requirements of the protocol OBD to include the indirect control of engine wear. To meet the objectives set out above measurement was carried out by a petrol engine, which was located in the vehicle Škoda Felicia Combi GLX 1.3 The whole measurement was divided into several parts. The first measurement was carried out on the abovementioned motor without simulating leakage. The second measurement was performed when the leakage of one cylinder was simulated. Simulated leakage was conducted at removing the spark plugs. Other measurements simulated “mild” leak of the whole engine – all cylinders. Leakage was implemented by loosing all the spark plugs about 8 turns against full tightening with the appropriate torque. The last, fourth measurement simulates a “large” leaks of engine cylinders. This leakage was induced by removing all the spark plugs from all cylinders. As the measurement results showed leakage of one cylinder, and also the whole engine is reflected not only in the individual amplitude of the starter current, but also the shape of the entire curve.

  2. Flue gas conditioning for improved particle collection in electrostatic precipitators. Quarterly technical report

    Energy Technology Data Exchange (ETDEWEB)

    Durham, M.D.

    1992-04-27

    The purpose of this research program is to identify and evaluate a variety of additives capable of increasing particle cohesion which could be used for improving collection efficiency in an ESP. A three-phase screening process will be used to provide the, evaluation of many additives in a logical and cost-effective manner. The three step approach involves the following experimental setups: 1. Provide a preliminary screening in the laboratory by measuring the effects of various conditioning agents on reentrainment of flyash particles in an electric field operating at simulated flue gas conditions. 2. Evaluate the successful additives using a 100 acfm bench-scale ESP operating on actual flue gas. 3. Obtain the data required for scaling up the technology by testing the two or three most promising conditioning agents at the pilot scale.

  3. How does pattern of feeding and rate of nutrient delivery influence conditioned food preferences?

    Science.gov (United States)

    Duncan, A J; Elwert, C; Villalba, J J; Yearsley, J; Pouloupoulou, I; Gordon, I J

    2007-09-01

    Ruminant herbivores have been shown to learn about food properties by associating food flavours with the food's post-ingestive consequences. Previous experimentation supporting the conditioned food aversion/preference hypothesis has generally employed very simple diet learning tasks which do not effectively represent the wide range of foods selected within single bouts typical of wild, free-ranging ruminant herbivores. We tested the ability of a ruminant herbivore to associate a food with artificially administered nutrient rewards in a designed experiment where we altered the temporal pattern of encounter with the food as well as the nature (fast or slow reward) of the post-ingestive outcome. Twenty-four goats were offered branches of Sitka spruce (SS) and Norway spruce (NS) for 4 h per day on two days per week for five weeks. The pattern of feeding varied with treatment such that the species on offer changed every hour (short) or every 2 h (long). The energy treatment altered the reward delivered during Sitka consumption so that animals were dosed either with predominantly sugar (rapidly fermented), predominantly starch (slower fermentation rate), or with water (placebo). Preference was measured on the day following each learning day. We expected that goats would find it easier to associate SS with post-ingestive rewards when the duration of encounter was longest, and that associations would be stronger with the most rapidly digested post-ingestive reward. In the event, goats did not alter their consumption of SS in response to the treatments. Our results suggest that at the scale of temporal resolution of encounters with different plant species (1-2 h), and at the different rates of experiencing post-ingestive consequences tested in this experiment, ruminants do not appear to discriminate the nutritive properties of foods predominantly through a post-ingestive feedback mechanism. They must, instead, use a range of cues-including post-ingestive consequences

  4. Assessment of technical condition of concrete pavement by the example of district road

    Science.gov (United States)

    Linek, M.; Nita, P.; Żebrowski, W.; Wolka, P.

    2018-05-01

    The article presents the comprehensive assessment of concrete pavement condition. Analyses included the district road located in the swietokrzyskie province, used for 11 years. Comparative analyses were conducted twice. The first analysis was carried out after 9 years of pavement operation, in 2015. In order to assess the extent of pavement degradation, the tests were repeated in 2017. Within the scope of field research, the traffic intensity within the analysed road section was determined. Visual assessment of pavement condition was conducted, according to the guidelines included in SOSN-B. Visual assessment can be extended by ground-penetrating radar measurements which allow to provide comprehensive assessment of the occurred structure changes within its entire thickness and length. The assessment included also performance parameters, i.e. pavement regularity, surface roughness and texture. Extension of test results by the assessment of changes in internal structure of concrete composite and structure observations by means of Scanning Electron Microscope allow for the assessment of parameters of internal structure of hardened concrete. Supplementing the observations of internal structure by means of computed tomography scan provides comprehensive information of possible discontinuities and composite structure. According to the analysis of the obtained results, conclusions concerning the analysed pavement condition were reached. It was determined that the pavement is distinguished by high performance parameters, its condition is good and it does not require any repairs. Maintenance treatment was suggested in order to extend the period of proper operation of the analysed pavement.

  5. Technical, economic and legal boundary conditions of district heating. Pt. 2; Technische, wirtschaftliche und rechtliche Rahmenbedingungen der Fernwaermewirtschaft. T. 2. Besondere Rechtslage

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Norman [AGFW - Der Energieeffizienzverband fuer Waerme, Kaelte und KWK e.V., Frankfurt am Main (Germany)

    2011-04-15

    It is a common misconception that legal regulations of the electricity and gas industry can also be applied to district heating. However, the technical, economic and legal boundary conditions of district heating are quite different. The first part of this article explained the concept of district heating and analyzed its economic boundary conditions. This contribution explains the heat market and its legal boundary conditions.

  6. A technical basis for the flux corrected local conditions critical heat flux correlation

    International Nuclear Information System (INIS)

    Luxat, J.C.

    2008-01-01

    The so-called 'flux-corrected' local conditions CHF correlation was developed at Ontario Hydro in the 1980's and was demonstrated to successfully correlate the Onset of Intermittent Dryout (OID) CHF data for 37-element fuel with a downstream-skewed axial heat flux distribution. However, because the heat flux correction factor appeared to be an ad-hoc, albeit a successful modifying factor in the correlation, there was reluctance to accept the correlation more generally. This paper presents a thermalhydraulic basis, derived from two-phase flow considerations, that supports the appropriateness of the heat flux correction as a local effects modifying factor. (author)

  7. Analysis of the prevailing standard and technical documents for their applicability under conditions of the 'Ukrytie' operation and technical proposals relating to the elaboration of new ones concerning fire safety

    International Nuclear Information System (INIS)

    Nazarenko, B.S.; Emets, V.G.

    1998-01-01

    An analysis of the prevailing laws and standards and technical documents (STD) to ensure safe operation of nuclear power installations, with requirements of nuclear, radiation and fire safety taken into account, has been performed. Proposals on application of some items of prevailing STD under conditions of the 'Ukrytie' operation are presented. Also given are technical proposals on correction of the prevailing operational standard documents and elaboration of special STD

  8. Technical issues and conservation conditions of medicines in the primary health care of the Brazilian Unified Health System

    Science.gov (United States)

    Costa, Ediná Alves; Araújo, Patrícia Sodré; Pereira, Marcelo Tavares; Souto, Ana Cristina; Souza, Gisélia Santana; Guerra, Augusto Afonso; Acurcio, Francisco de Assis; Guibu, Ione Aquemi; Alvares, Juliana; Costa, Karen Sarmento; Karnikowski, Margô Gomes de Oliveira; Soeiro, Orlando Mario; Leite, Silvana Nair

    2017-01-01

    ABSTRACT OBJECTIVE To characterize the technical issues and conditions of medicines conservation in Primary Health Care of Brazilian regions, responsible for pharmacy/dispensing unit profile; environmental, storage, and dose fractioning conditions; inventory control and waste management; fire and electrical failure safety items; transportation problems; advertising regulation; and pharmacovigilance. METHODS This article is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos – Serviços (National Survey on Access, Use and Promotion of Rational Use of Medicines – Services)–, a cross-sectional and exploratory study, of evaluative nature, consisting of an information survey within a representative sample of municipalities, stratified by Brazilian regions, which constitute the study domains, and a sample of Primary Health Care services. Pharmaceutical services (PS) were directly observed with photographic record and face-to-face interviews with those responsible for the dispensing of medicines and over the telephone with those responsible for pharmaceutical services. Data were processed with the SPSS® software version 21. RESULTS The investigated dimensions showed relevant deficiencies and inequalities between the regions, generally more favorable in the Southeast and Midwest regions and weaker in the Northeast and North regions. We verified non-compliance with technical requirements and conditions essential to the conservation of medicines, which may interfere with the maintenance of stability and, thus, on their quality, efficacy, and safety. The regulation of advertising/promotion of medicines is still incipient and there is some progress in the structuring of mechanisms regarding pharmacovigilance. CONCLUSIONS The sanitary situation of medicines in Brazilian Primary Health Care is alarming due to the violation of the specific sanitary legislation for dispensing establishments and due to a wide range of

  9. Objective Structured Assessment of Technical Skills (OSATS) evaluation of theoretical versus hands-on training of vaginal breech delivery management: a randomized trial.

    Science.gov (United States)

    Buerkle, Bernd; Rueter, Katharina; Hefler, Lukas A; Tempfer-Bentz, Eva-Katrin; Tempfer, Clemens B

    2013-12-01

    To compare the skills of performing a vaginal breech (VB) delivery after hands-on training versus demonstration. We randomized medical students to a 30-min demonstration (group 1) or a 30-min hands-on (group 2) training session using a standardized VB management algorithm on a pelvic training model. Subjects were tested with a 25 item Objective Structured Assessment of Technical Skills (OSATS) scoring system immediately after training and 72 h thereafter. OSATS scores were the primary outcome. Performance time (PT), self assessment (SA), confidence (CON), and global rating scale (GRS) were the secondary outcomes. Statistics were performed using the Mann-Whitney U-test, chi-square test, and multiple linear regression analysis. 172 subjects were randomized. OSATS scores (primary outcome) were significantly higher in group 2 (n=88) compared to group 1 (n=84) (21.18±2.29 vs. 20.19±2.37, respectively; p=0.006). The secondary outcomes GRS (10.31±2.28 vs. 9.17±2.21; p=0.001), PT (214.60±57.97 s vs. 246.98±59.34 s; ptraining leads to a significant improvement of VB management in a pelvic training model, but this effect was only seen in the short term. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  10. A randomized comparison of video demonstration versus hands-on training of medical students for vacuum delivery using Objective Structured Assessment of Technical Skills (OSATS).

    Science.gov (United States)

    Hilal, Ziad; Kumpernatz, Anne K; Rezniczek, Günther A; Cetin, Cem; Tempfer-Bentz, Eva-Katrin; Tempfer, Clemens B

    2017-03-01

    To compare medical students' skills for vaginal operative delivery by vacuum extraction (VE) after hands-on training versus video demonstration. We randomized medical students to an expert demonstration (group 1) or a hands-on (group 2) training using a standardized VE algorithm on a pelvic training model. Students were tested with a 40-item Objective Structured Assessment of Technical Skills (OSATS) scoring system after training and 4 days later. OSATS scores were the primary outcome. Performance time, self-assessment, confidence, and global rating scale were secondary outcomes. We assessed the constructive validity of OSATS in this VE model comparing metric scores of experts and students. In all, 137 students were randomized. OSATS scores were higher in group 2 (n = 63) compared with group 1 (n = 74) (32.89 ± 6.39 vs 27.51 ± 10.27, respectively; P training is superior to video demonstration for teaching VE on a pelvic model.

  11. Technical Note: Quantification of interferences of wet chemical HONO LOPAP measurements under simulated polar conditions

    Directory of Open Access Journals (Sweden)

    J. Kleffmann

    2008-11-01

    Full Text Available In the present pilot study, an optimized LOPAP instrument (LOng Path Absorption Photometer for the detection of nitrous acid (HONO in the atmosphere (DL 0.2 pptV was tested at the high alpine research station Jungfraujoch at 3580 m altitude in the Swiss Alps under conditions comparable to polar regions. HONO concentrations in the range <0.5–50 pptV with an average of 7.5 pptV were observed at the Jungfraujoch. The diurnal profiles obtained exhibited clear maxima at noon and minima with very low concentration during the night supporting the proposed photochemical production of HONO. In good agreement with recent measurements at the South Pole, it was demonstrated, that interferences of chemical HONO instruments can significantly influence the measurements and lead to considerable overestimations, especially for low pollution level. Accordingly, the active correction of interferences is of paramount importance for the determination of reliable HONO data.

  12. Technical Report on Preliminary Methodology for Enhancing Risk Monitors with Integrated Equipment Condition Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Ramuhalli, Pradeep; Coles, Garill A.; Coble, Jamie B.; Hirt, Evelyn H.

    2013-09-17

    Small modular reactors (SMRs) generally include reactors with electric output of ~350 MWe or less (this cutoff varies somewhat but is substantially less than full-size plant output of 700 MWe or more). Advanced SMRs (AdvSMRs) refer to a specific class of SMRs and are based on modularization of advanced reactor concepts. AdvSMRs may provide a longer-term alternative to traditional light-water reactors (LWRs) and SMRs based on integral pressurized water reactor concepts currently being considered. Enhancing affordability of AdvSMRs will be critical to ensuring wider deployment. AdvSMRs suffer from loss of economies of scale inherent in small reactors when compared to large (~greater than 600 MWe output) reactors. Some of this loss can be recovered through reduced capital costs through smaller size, fewer components, modular fabrication processes, and the opportunity for modular construction. However, the controllable day-to-day costs of AdvSMRs will be dominated by operation and maintenance (O&M) costs. Technologies that help characterize real-time risk are important for controlling O&M costs. Risk monitors are used in current nuclear power plants to provide a point-in-time estimate of the system risk given the current plant configuration (e.g., equipment availability, operational regime, and environmental conditions). However, current risk monitors are unable to support the capability requirements listed above as they do not take into account plant-specific normal, abnormal, and deteriorating states of active components and systems. This report documents technology developments that are a step towards enhancing risk monitors that, if integrated with supervisory plant control systems, can provide the capability requirements listed and meet the goals of controlling O&M costs. The report describes research results from an initial methodology for enhanced risk monitors by integrating real-time information about equipment condition and POF into risk monitors.

  13. Assessment and Analysis of Smolt Condition in the Columbia River Basin, 1999 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Schrock, Robin M.; Jones, Ray

    1999-12-01

    The primary objective of the study was to increase the number of summer steelhead (Oncorhynchus mykiss) from Dworshak National Fish Hatchery that outmigrate by promoting smoltification in a larger proportion of the production release. To achieve this goal, growth was reduced during the winter to produce a smaller size range of fish to eliminate the production of large fish that residualize. A period of accelerated growth prior to release was designed to promote smoltification in all fish, regardless of size. Decreased winter growth was achieved with a combination of reduced ration and short, intermittent feeding periods. Growth rates were not reduced to the expected level in the modified feeding schedule treatment group, control group, or general production fish reared in the same system. Although significant differences in length, weight and condition factor developed between treatment and control groups during December and January, compensatory growth of the treatment fish after return to full rations resulted in fish of the same size from both groups for release. Migration rates of the treatment group were higher than that of the control group, although the difference was not significant. Growth and survival during extended seawater rearing did not differ between the two groups. Smoltification, as measured by gill Na{sup +}, K{sup +}-ATPase and seawater survival, were unaffected by a reduction in feed during winter months.

  14. A combined model to assess technical and economic consequences of changing conditions and management options for wastewater utilities.

    Science.gov (United States)

    Giessler, Mathias; Tränckner, Jens

    2018-02-01

    The paper presents a simplified model that quantifies economic and technical consequences of changing conditions in wastewater systems on utility level. It has been developed based on data from stakeholders and ministries, collected by a survey that determined resulting effects and adapted measures. The model comprises all substantial cost relevant assets and activities of a typical German wastewater utility. It consists of three modules: i) Sewer for describing the state development of sewer systems, ii) WWTP for process parameter consideration of waste water treatment plants (WWTP) and iii) Cost Accounting for calculation of expenses in the cost categories and resulting charges. Validity and accuracy of this model was verified by using historical data from an exemplary wastewater utility. Calculated process as well as economic parameters shows a high accuracy compared to measured parameters and given expenses. Thus, the model is proposed to support strategic, process oriented decision making on utility level. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Technical chemical conditions for alcohol production from beet-sugar molasses and starchy raw mateials

    Energy Technology Data Exchange (ETDEWEB)

    Zabrodskii, A G; Vitkovskaya, V A; Orlovskii, Ya K

    1963-01-01

    The industrial conditions for the combined use of these raw materials varies considerably from those for separate application. Calculation formulas are developed, and example calculations are shown, for yields, purity coefficient, conversion values after saccharification of potato and grain starches, and mash concentrations prior to mixing with molasses mash for optimum yields. Of high importance is the acidity adjustment prior to fermentation. The molasses mash joining the saccharified starch mash is so adjusted as to produce a final mixture of pH 5.3 to 5.6, and to titrate with saccharified grain starch 0.25 to 0.3/sup 0/ acidity, and with potato starch 0.3 to 0.4/sup 0/. The reduction of molasses alkalinity by 1/sup 0/ (1/sup 0/ alkalinity corresponds during titration to 1 cc. of N H/sub 2/SO/sub 4/ in 100 g. molasses) for 1 ton requires 270 cc. H/sub 2/SO/sub 4/ (monohydrate) or 770 cc. HCl (sp. gr. 1.19). For acidifying 1 m./sup 3/ molasses mash by 0.1/sup 0/, 140 cc. H/sub 2/SO/sub 4/ or 400 cc. HCl are needed. Molasses are diluted and sterilized at 85 to 90/sup 0/ for 30 to 45 minutes, cooled down, and adjusted with cold water to the required sugar content. Yeast is added to provide a concentration of 80 to 90 million/cc. in grain- or potato-starch mash prior to admixture of molasses mash; it reaches 130 to 140 million cc. after completion of admixture. The molasses mash is added after the starch mash has fermented down to 10 to 11% and the addition takes 8 to 10 hours for a total fermentation time of 48 hours.

  16. Regulation on the general conditions of sale and delivery of radioactive materials of the 15th December 1987

    International Nuclear Information System (INIS)

    1988-01-01

    The regulation governing the cooperation between suppliers and customers of radioactive materials was issued by the Ministry of Chemical Industry and entered into force on 1 March 1988. The following articles are covered: definition, contents and form of supply contracts, licensing and registration, quality and labelling, delivery note, transport, terms of delivery, quality control, packaging, and reuse

  17. Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury

    Directory of Open Access Journals (Sweden)

    Dasa Cizkova

    2018-03-01

    Full Text Available It was recently shown that the conditioned medium (CM of mesenchymal stem cells can enhance viability of neural and glial cell populations. In the present study, we have investigated a cell-free approach via CM from rat bone marrow stromal cells (MScCM applied intrathecally (IT for spinal cord injury (SCI recovery in adult rats. Functional in vitro test on dorsal root ganglion (DRG primary cultures confirmed biological properties of collected MScCM for production of neurosphere-like structures and axon outgrowth. Afterwards, rats underwent SCI and were treated with IT delivery of MScCM or vehicle at postsurgical Days 1, 5, 9, and 13, and left to survive 10 weeks. Rats that received MScCM showed significantly higher motor function recovery, increase in spared spinal cord tissue, enhanced GAP-43 expression and attenuated inflammation in comparison with vehicle-treated rats. Spared tissue around the lesion site was infiltrated with GAP-43-labeled axons at four weeks that gradually decreased at 10 weeks. Finally, a cytokine array performed on spinal cord extracts after MScCM treatment revealed decreased levels of IL-2, IL-6 and TNFα when compared to vehicle group. In conclusion, our results suggest that molecular cocktail found in MScCM is favorable for final neuroregeneration after SCI.

  18. Modernization of the automation control system of technological processes at the preparation plant in the conditions of technical re-equipment

    Science.gov (United States)

    Lyakhovets, M. V.; Wenger, K. G.; Myshlyaev, L. P.; Shipunov, M. V.; Grachev, V. V.; Melkozerov, M. Yu; Fairoshin, Sh A.

    2018-05-01

    The experience of modernization of the automation control system of technological processes at the preparation plant under the conditions of technical re-equipment of the preparation plant “Barzasskoye Tovarischestvo” LLC (Berezovsky) is considered. The automated process control systems (APCS), the modernization goals and the ways to achieve them are indicated, the main subsystems of the integrated APCS are presented, the enlarged functional and technical structure of the upgraded system is given. The procedure for commissioning an upgraded system is described.

  19. Technical performance characterization of fourier transform profilometry for quantitative waste volume determination under Hanford waste tank conditions - 16281

    International Nuclear Information System (INIS)

    Monts, David L.; Jang, Ping-Rey; Long, Zhiling; Norton, Olin P.; Gresham, Lawrence L.; Su, Yi; Lindner, Jeffrey S.

    2009-01-01

    The Hanford Site in western Washington state is currently in the process of an extensive effort to empty and close its radioactive single-shell and double-shell waste storage tanks. Before this can be accomplished, it is necessary to know how much residual material is left in a given waste tank and the chemical makeup of the residue. The Institute for Clean Energy Technology (ICET) at Mississippi State University is currently developing an quantitative in-tank inspection system based on Fourier Transform Profilometry, FTP. FTP is a non-contact, 3-D shape measurement technique. By projecting a fringe pattern onto a target surface and observing its deformation due to surface irregularities from a different view angle, FTP is capable of determining the height (depth) distribution (and hence volume distribution) of the target surface, thus reproducing the profile of the target accurately under a wide variety of conditions. Hence FTP has the potential to be utilized for quantitative determination of residual wastes within Hanford waste tanks. We report the results of a technical feasibility study to document the accuracy and precision of quantitative volume determination using the Fourier transform profilometry technique under simulated Hanford waste tank conditions. We have initiated a technical feasibility assessment of the Fourier transform profilometry (FTP) technique for determining the volume of residual waste in Hanford radioactive waste tanks; preliminary results to date are presented in this paper. We find that we achieve FTP volume determinations with relatively small errors under conditions corresponding to the most challenging within a Hanford waste tank-viewing non-descript targets at a distance of 16.1 m (53 ft) and an angle of 62 deg.. We have determined that we can minimize measurement uncertainty by maximizing the camera-to-projector distance d, using an optical zoom of at least 5x, and ensuring that FTP images are only recorded after instrumental warm

  20. Technical Performance Capability of Fourier Transform Profilometry for Quantitative Waste Volume Determination under Hanford Waste Tank Condition

    International Nuclear Information System (INIS)

    Monts, D.L.; Jang, P.R.; Long, Z.; Norton, O.P.; Okhuysen, W.P.; Su, Y.; Waggoner, Ch.A.

    2009-01-01

    The Hanford Site is currently in the process of an extensive effort to empty and close its radioactive single-shell and double-shell waste storage tanks. Before this can be accomplished, it is necessary to know how much residual material is left in a given waste tank and the chemical makeup of the residue. The Institute for Clean Energy Technology (ICET) at Mississippi State University is currently developing a quantitative in-tank inspection system based on Fourier Transform Profilometry (FTP). FTP is a non-contact, 3-D shape measurement technique. By projecting a fringe pattern onto a target surface and observing its deformation due to surface irregularities from a different view angle, FTP is capable of determining the height (depth) distribution (and hence volume distribution) of the target surface, thus reproducing the profile of the target accurately under a wide variety of conditions. Hence FTP has the potential to be utilized for quantitative determination of residual wastes within Hanford waste tanks. We report the results of a technical feasibility study to document the accuracy and precision of quantitative volume determination using the Fourier transform profilometry technique under simulated Hanford waste tank conditions. (authors)

  1. Technical, economic and legal boundary conditions of district heating. Pt. 1; Besondere Rechtslage. Technische, wirtschaftliche und rechtliche Rahmenbedingungen der Fernwaermewirtschaft. T. 1

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Norman [AGFW Der Energieeffizienzverband fuer Waerme, Kaelte und KWK e.V., Frankfurt am Main (Germany)

    2011-03-15

    Often, legal regulations governing the electricity and gas industries are thought prematurely to apply to district heating as well. The author shows that the technical and economic boundary conditions of district heating are quite different in many respects. He starts by explaining the concept of district heating and analyzing its economic boundary conditions. The next instalment will follow in the next issue of EuroHeat and Power and will focus on the heat market and its legal boundary conditions.

  2. HVAC-DYNAMICS - a tool for quality assurance in relation to delivery of air-conditioning systems. [Heating, ventilating and air conditioning]. HVAC-DYNAMICS - et redskap for kvalitetsikring av sluttleveransen i klima-anlegg

    Energy Technology Data Exchange (ETDEWEB)

    Novakovic, V [SINTEF Varmeteknikk, Seksjon VVS (NO)

    1990-07-01

    HVAC-DYNAMICS is a computerized tool for quality assurance of the functioning of an air-conditioning system at the time of delivery. The system's efficiency in the case of fluctuating and critical operation is evaluated. The HVAC-DYNAMICS gives an optimal choice for air-conditioning systems regarding indoor climate, efficiency demands and energy consumption. The program can also be use for calibration of regulators, fault-finding, and training purposes. (CLS).

  3. Technical innovation and management

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Yang Cheol

    1982-08-15

    This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

  4. Technical innovation and management

    International Nuclear Information System (INIS)

    Yoon, Yang Cheol

    1982-08-01

    This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

  5. The Condition of Young Children in Sub-Saharan Africa: The Convergence of Health, Nutrition, and Early Education. World Bank Technical Paper No. 326, Africa Technical Department Series.

    Science.gov (United States)

    Colletta, Nat J.; And Others

    In Sub-Saharan Africa, severe adverse conditions have placed children at high risk: persistent and worsening poverty, rapid economic change and population growth, increasing urbanization, a changing family structure, growing numbers of orphaned refugees, and displaced women and children from internal civil strife. These conditions make a viable…

  6. Assessing the dose values received by patients during conventional radiography X-ray examinations and the technical condition of the equipment used for this purpose.

    Science.gov (United States)

    Bekas, Marcin; Pachocki, Krzysztof A; Waśniewska, Elżbieta; Bogucka, Dagmara; Magiera, Andrzej

    2014-01-01

    X-ray examination is associated with patient exposure to ionizing radiation. Dose values depend on the type of medical procedure used, the X-ray unit technical condition and exposure conditions selected. The aim of this study was to determine the dose value received by patients during certain conventional radiography X-ray examinations and to assess the technical condition of medical equipment used for this purpose. The study covered the total number of 118 conventional diagnostic X-ray units located in the Masovian Voivodeship. The methodology used to assess the conventional diagnostic X-ray unit technical condition and the measurement of the radiation dose rate received by patients are based on test procedures developed by the Department of Radiation Protection and Radiobiology of the National Institute of Public Health - National Institute of Hygiene (Warszawa, Poland) accredited for compliance with PN-EN 17025 standard by the Polish Centre for Accreditation. It was found that 84.7% of X-ray units fully meet the criteria set out in the Polish legislation regarding the safe use of ionizing radiation in medicine, while 15.3% of the units do not meet some of them. The broadest dose value range was recorded for adult patients. Particularly, during lateral (LATl) lumbar spine radiography the recorded entrance surface dose (ESD) values ranged from 283.5 to 7827 µGy (mean: 2183.3 µGy). It is absolutely necessary to constantly monitor the technical condition of all X-ray units, because it affects population exposure to ionizing radiation. Furthermore, it is essential to raise radiographers' awareness of the effects that ionizing radiation exposure can have on the human body.

  7. Organization of work with training mathematical text for technical university students under conditions of informatization of education

    Directory of Open Access Journals (Sweden)

    Михаил Владимирович Поспелов

    2013-12-01

    Full Text Available This article describes the model of the organization of working with training mathematical text for technical university students. Need for development of training text works competencies of first-year students is proved. The impact of learning materials transition into hypertext format on training text works organizing theory is cleared. Training text works organizing stages are described.

  8. Flood Protection in Venice under Conditions of Sea-Level Rise: An Analysis of Institutional and Technical Measures

    NARCIS (Netherlands)

    Munaretto, S.; Vellinga, P.; Tobi, H.

    2012-01-01

    It is widely acknowledged that in times of climate change loss of coastal resources and risk for human life can be minimized by implementing adaptation strategies. Such strategies need to encompass a balanced mix of non-structural (institutional) and structural (technical) measures based on sound

  9. Development of a quantitative evaluation method for non-technical skills preparedness of operation teams in nuclear power plants to deal with emergency conditions

    International Nuclear Information System (INIS)

    Yim, Ho Bin; Kim, Ar Ryum; Seong, Poong Hyun

    2013-01-01

    Highlights: ► We selected important non-technical skills for emergency conditions in NPPs. ► We proposed an evaluation method for the selected non-technical skills. ► We conducted two sets of training, 9 experiments each, with real plant operators. ► Teams showed consistent non-technical skills preparedness with changing scenarios. ► Non-technical skills preparedness gives plausible explanations why teams fail tasks. -- Abstract: Many statistical results from safety reports tell that human related errors are the dominant influencing factor on the safe operation of power plants. Fortunately, training operators for the technical and non-technical skills can prevent many types of human errors. In this study, four important non-technical skills in safety critical industries – medical, aviation, and nuclear – were selected to describe behaviors of operation teams in emergency conditions of nuclear power plants (NPPs): communication, leadership, situation awareness, and decision-making skills. Also, preparedness of the non-technical skills was defined, and a quantification method of those skills called NoT-SkiP (Non-Technical Skills Preparedness) was developed to represent ‘how well operation teams are prepared to deal with emergency conditions’ in the non-technical skills aspect by analyzing monitoring-control patterns and a verbal protocol. Two case studies were conducted to validate the method. The first case was applied to Loss of Coolant Accident (LOCA) and Steam Generator Tube Rupture (SGTR) training. Independent variables were scenario, training repetition, and members. Relative values of the NoT-SkiP showed a consistent trend with changing scenarios. However, when training was repeated with the same scenario, NoT-SkiP values of some team were changed. It was supposed that leaders of some teams exerted their knowledge acquired from the previous training and gave up thoroughness of using procedures. When members especially who play a dominant role

  10. Development of a quantitative evaluation method for non-technical skills preparedness of operation teams in nuclear power plants to deal with emergency conditions

    Energy Technology Data Exchange (ETDEWEB)

    Yim, Ho Bin; Kim, Ar Ryum [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Seong, Poong Hyun, E-mail: phseong@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of)

    2013-02-15

    Highlights: ► We selected important non-technical skills for emergency conditions in NPPs. ► We proposed an evaluation method for the selected non-technical skills. ► We conducted two sets of training, 9 experiments each, with real plant operators. ► Teams showed consistent non-technical skills preparedness with changing scenarios. ► Non-technical skills preparedness gives plausible explanations why teams fail tasks. -- Abstract: Many statistical results from safety reports tell that human related errors are the dominant influencing factor on the safe operation of power plants. Fortunately, training operators for the technical and non-technical skills can prevent many types of human errors. In this study, four important non-technical skills in safety critical industries – medical, aviation, and nuclear – were selected to describe behaviors of operation teams in emergency conditions of nuclear power plants (NPPs): communication, leadership, situation awareness, and decision-making skills. Also, preparedness of the non-technical skills was defined, and a quantification method of those skills called NoT-SkiP (Non-Technical Skills Preparedness) was developed to represent ‘how well operation teams are prepared to deal with emergency conditions’ in the non-technical skills aspect by analyzing monitoring-control patterns and a verbal protocol. Two case studies were conducted to validate the method. The first case was applied to Loss of Coolant Accident (LOCA) and Steam Generator Tube Rupture (SGTR) training. Independent variables were scenario, training repetition, and members. Relative values of the NoT-SkiP showed a consistent trend with changing scenarios. However, when training was repeated with the same scenario, NoT-SkiP values of some team were changed. It was supposed that leaders of some teams exerted their knowledge acquired from the previous training and gave up thoroughness of using procedures. When members especially who play a dominant role

  11. ON THE NECESSITY OF CHANGES IN THE STRATEGY OF UTILIZATION SHIP BOILER TECHNICAL CONDITION MAINTENANCE IN THE ASPECT OF LNG APPLIED AS FUEL

    Directory of Open Access Journals (Sweden)

    Andrzej ADAMKIEWICZ

    2017-01-01

    Full Text Available Heavy oils (HFO fuels used on ships play a part in degradation of technical condition of heat exchange surfaces of utiliza-tion boilers especially on the exhaust gas side. Presence of sulphur in these fuels is the main factor favouring degrada-tion. The upper limit for sulphur content in the fuel used outside the SECA areas equal to 3.5% is currently in force, at least until the year 2020 or 2025. The recommended by classification societies overhauls of utilization boilers are, there-fore characterized by a specially chosen strategy thanks to which it is possible to maintain their appropriate technical condition. The requirement to use fuels with low sulphur content (LSFO, which are significantly more expensive than MDO fuels, in the areas of controlled sulphur emissions also led to a further introduction of alternative fuels, such as methanol and above all liquefied natural gas (LNG, onto ships. That is especially valid for the ship owners whose vessels e.g. ferries sail mainly within SCECA This article analyses the consequences of the introduced fuel change on utilization boiler maintenance. A change in the technical condition maintenance strategy for utilization boilers has been suggested.

  12. Comparative studies to the design of the interferometer at W7-X with respect to technical boundary conditions

    International Nuclear Information System (INIS)

    Dreier, H.; Dinklage, A.; Hirsch, M.; Kornejew, P.; Fischer, R.

    2008-01-01

    For the optimisation of the beam line configuration of the multi-channel interferometer at the Wendelstein 7-X stellarator the probabilistic approach of Bayesian experimental design (BED) is applied. Parameters of physical interest are directly implemented as design criteria. The quality of the design is analysed according to its expected information gain (expected utility) about the parameters of interest, which enables one to compare different diagnostic configurations quantitatively. The focus of this work lies on the comparison of different technical approaches for the interferometer diagnostic. Different physical problems (high confinement regimes, neoclassical predictions) and their effect on the density distribution are applied as optimisation goals. The influence of the port system and the in-vessel components (retro-reflectors) is discussed. For this, the design was done with and without technical restrictions, the resulting expected utilities are compared and analysed. Furthermore, the impact of an additional beamline at a different toroidal position (congruent to the Thomson scattering diagnostic) is examined

  13. SU-E-T-403: Evaluation of the Beam Performance of a Varian TrueBeam Linear Accelerator Under External Device-Based Gated Delivery Conditions

    International Nuclear Information System (INIS)

    Kobulnicky, K; Pawlak, D; Purwar, A

    2015-01-01

    Purpose: To examine the beam performance of a Varian TrueBeam linear accelerator under external device-based gated delivery conditions. Methods: Six gating cycles were used to evaluate the gating performance of a standard production TrueBeam system that was not specially tuned in any way. The system was equipped with a factory installed external gating interface (EXGI). An in-house EXGI tester box was used to simulate the input gating signals. The gating cycles were selected based on long beam-on and short beam-off times, short beam-on and long beam-off times, or equal beam on and off times to check linac performance. The beam latencies were measured as the time difference between the logic high gating signal and the first or last target pulses with an oscilloscope. Tissue-Phantom Ratio, beam flatness, and dose distributions from 5 different plans were measured using the 6 different gating durations and the un-gated irradiation. A PTW 729 2-D array was used to compare 5 plans versus the un-gated delivery with a 1%/1mm gamma index passing criteria. Results: The beam latencies of the linac were based off of 20 samples for beam-on and beam-off, for each gating cycle. The average beam-on delays were measured to be between 57 and 66msec, with a maximum of 88 msec. The beam off latencies averaged between 19 and 26msec, with a maximum of 48 msec. TPR20,10 measurements showed beam energy stability within 0.5% of the un-gated delivery. Beam flatness was better than 2.5% for all gated cycles. All but two deliveries, the open field with 4 seconds on, 1 second off, and a five field IMRT plan with 0.5 seconds on, 2.5 seconds off, had >90% passing rate. Conclusion: TrueBeam demonstrates excellent beam stability with minimal beam latencies under external device-based gated operations. Dosimetric measurements show minimal variation in beam energy, flatness, and plan delivery. Authors are employees of Varian Medical Systems, Inc

  14. SU-E-T-403: Evaluation of the Beam Performance of a Varian TrueBeam Linear Accelerator Under External Device-Based Gated Delivery Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Kobulnicky, K; Pawlak, D; Purwar, A [Varian Medical Systems, Inc., Palo Alto, CA (United States)

    2015-06-15

    Purpose: To examine the beam performance of a Varian TrueBeam linear accelerator under external device-based gated delivery conditions. Methods: Six gating cycles were used to evaluate the gating performance of a standard production TrueBeam system that was not specially tuned in any way. The system was equipped with a factory installed external gating interface (EXGI). An in-house EXGI tester box was used to simulate the input gating signals. The gating cycles were selected based on long beam-on and short beam-off times, short beam-on and long beam-off times, or equal beam on and off times to check linac performance. The beam latencies were measured as the time difference between the logic high gating signal and the first or last target pulses with an oscilloscope. Tissue-Phantom Ratio, beam flatness, and dose distributions from 5 different plans were measured using the 6 different gating durations and the un-gated irradiation. A PTW 729 2-D array was used to compare 5 plans versus the un-gated delivery with a 1%/1mm gamma index passing criteria. Results: The beam latencies of the linac were based off of 20 samples for beam-on and beam-off, for each gating cycle. The average beam-on delays were measured to be between 57 and 66msec, with a maximum of 88 msec. The beam off latencies averaged between 19 and 26msec, with a maximum of 48 msec. TPR20,10 measurements showed beam energy stability within 0.5% of the un-gated delivery. Beam flatness was better than 2.5% for all gated cycles. All but two deliveries, the open field with 4 seconds on, 1 second off, and a five field IMRT plan with 0.5 seconds on, 2.5 seconds off, had >90% passing rate. Conclusion: TrueBeam demonstrates excellent beam stability with minimal beam latencies under external device-based gated operations. Dosimetric measurements show minimal variation in beam energy, flatness, and plan delivery. Authors are employees of Varian Medical Systems, Inc.

  15. Technical report Development of a piezoelectric inkjet dopant delivery device for an atmospheric pressure photoionization source with liquid chromatography/mass spectrometry

    KAUST Repository

    Amad, Maan H.

    2013-01-01

    This paper describes a simple robust and integrated piezoelectric actuated printhead as a dopant delivery system for atmospheric pressure photoionization with liquid chromatography/mass spectrometry The newly designed dopant delivery system avoids problems associated with traditional liquid delivery systems such as solvent immiscibility backpressure and increased post-column dead volume issues The performance of the new device was tested and evaluated using chlorobenzene as a dopant with a test mixture consisting of 18 different polycyclic aromatic hydrocarbons (PAHs) The results show that the new system works robustly at low dopant consumption level (16 uL min-1) consuming only approximately 5% of the amount used by conventional sources The low dopant consumption has resulted in up to a 20-fold reduction in signal intensity of tested PAH molecules but has led to less presence of background cluster ions and dopant trace contaminant background ions in the source area Consequently all tested PAHs were detected with excellent signal-to-noise ratio with at least two-to ten-fold improvements in the limit of detection and quantification compared to those obtained with traditional dopant assistance using a post-column addition method © IM Publications LLP 2013.

  16. Production controls (PC) and technical verification testing (TVT). A methodology for the control and tracking of LILW waste package conditioning

    International Nuclear Information System (INIS)

    Leon, A.M.; Nieto, J.L.L.; Garrido, J.G.

    2003-01-01

    As part of its low and intermediate level radioactive waste (LILW) characterisation and acceptance activities, ENRESA has set up a quality control programme that covers the different phases of radioactive waste package production and implies different levels of tracking in generation, assessment of activity and control of the documentation associated therewith. Furthermore, ENRESA has made available the mechanisms required for verification, depending on the results of periodic sampling, of the quality of the end product delivered by the waste producers. Both processes are included within the framework of two programmes of complementary activities: production controls (PC) and technical verification testing (TVT). (orig.)

  17. Optimizing oxygenation and intubation conditions during awake fibre-optic intubation using a high-flow nasal oxygen-delivery system.

    Science.gov (United States)

    Badiger, S; John, M; Fearnley, R A; Ahmad, I

    2015-10-01

    Awake fibre-optic intubation is a widely practised technique for anticipated difficult airway management. Despite the administration of supplemental oxygen during the procedure, patients are still at risk of hypoxia because of the effects of sedation, local anaesthesia, procedural complications, and the presence of co-morbidities. Traditionally used oxygen-delivery devices are low flow, and most do not have a sufficient reservoir or allow adequate fresh gas flow to meet the patient's peak inspiratory flow rate, nor provide an adequate fractional inspired oxygen concentration to prevent desaturation should complications arise. A prospective observational study was conducted using a high-flow humidified transnasal oxygen-delivery system during awake fibre-optic intubation in 50 patients with anticipated difficult airways. There were no episodes of desaturation or hypercapnia using the high-flow system, and in all patients the oxygen saturation improved above baseline values, despite one instance of apnoea resulting from over-sedation. All patients reported a comfortable experience using the device. The high-flow nasal oxygen-delivery system improves oxygenation saturation, decreases the risk of desaturation during the procedure, and potentially, optimizes conditions for awake fibre-optic intubation. The soft nasal cannulae uniquely allow continuous oxygenation and simultaneous passage of the fibrescope and tracheal tube. The safety of the procedure may be increased, because any obstruction, hypoventilation, or periods of apnoea that may arise may be tolerated for longer, allowing more time to achieve ventilation in an optimally oxygenated patient. © The Author 2015. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. National projections of forest and rangeland condition indicators: a supporting technical document for the 1999 RPA assessment.

    Science.gov (United States)

    John Hof; Curtis Flather; Tony Baltic; Stephen. Davies

    1999-01-01

    The 1999 forest and rangeland condition indicator model is a set of independent econometric production functions for environmental outputs (measured with condition indicators) at the national scale. This report documents the development of the database and the statistical estimation required by this particular production structure with emphasis on two special...

  19. Electronic apex locator: A comprehensive literature review — Part II: Effect of different clinical and technical conditions on electronic apex locator′s accuracy

    Directory of Open Access Journals (Sweden)

    Hamid Razavian

    2014-01-01

    Full Text Available Introduction: To investigate the effects of different clinical and technical conditions on the accuracy of electronic apex locators (EALs. Materials and Methods: "Tooth apex," "dental instrument," "odontometry," "electronic medical," and "electronic apex locator" were searched as primary identifiers via Medline/PubMed, Cochrane library, and Scopus data base up to 30 July 2013. Original articles that fulfilled the inclusion criteria were selected and reviewed. Results: Out of 402 relevant studies, 183 were selected based on the inclusion criteria. In this part, 75 studies are presented. Pulp vitality conditions and root resorption, types of files and irrigating materials do not affect an EAL′s accuracy; however, the file size and foramen diameter can affect its accuracy. Conclusions: Various clinical conditions such as the file size and foramen diameter may affect EALs′ accuracy. However, more randomized clinical trials are needed for definitive conclusion.

  20. Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions.

    Science.gov (United States)

    Itaka, Keiji; Harada, Atsushi; Nakamura, Kozo; Kawaguchi, Hiroshi; Kataoka, Kazunori

    2002-01-01

    The stability in physiological medium of polyplex- and lipoplex-type nonviral gene vectors was evaluated by detecting the conformational change of complexed plasmid DNA (pDNA) labeled simultaneously with fluorescein (energy donor) and X-rhodamine (energy acceptor) through fluorescence resonance energy transfer (FRET). Upon mixing with cationic components, such as LipofectAMINE, poly(L-lysine), and poly(ethylene glycol)-poly(L-lysine) block copolymer (PEG-PLys), the fluorescence spectrum of doubly labeled pDNA underwent a drastic change due to the occurrence of FRET between the donor-acceptor pair on pDNA taking a globular conformation (condensed state) through complexation. The measurement was carried out also in the presence of 20% serum, under which conditions FRET from condensed pDNA was clearly monitored without interference from coexisting components in the medium, allowing evaluation of the condensed state of pDNA in nonviral gene vectors under physiological conditions. Serum addition immediately induced a sharp decrease in FRET for the LipofectAMINE/pDNA (lipoplex) system, which was consistent with the sharp decrease in the transfection efficiency of the lipoplex system in serum-containing medium. In contrast, the PEG-PLys/pDNA polyplex (polyion complex micelle) system maintained appreciable transfection efficiency even in serum-containing medium, and FRET efficiency remained constant for up to 12 h, indicating the high stability of the polyion complex micelle under physiological conditions.

  1. The procedure for amendment of the technical conditions for electricity and natural gas. An essay on certain generally binding regulations

    International Nuclear Information System (INIS)

    Janssen, J.J.

    2009-01-01

    The energy law for the regulated Electricity and gas market has a stratified structure. The tariff structures and conditions that are established by the executive board of the Netherlands Competition Authority (NMa), based on article 36 of the Electricity Act 1998 and article 12f of the Gas Act, are in a way the tailpiece. This article focuses mainly on the procedure for amendment of these conditions. [nl

  2. Delivery presentations

    Science.gov (United States)

    Pregnancy - delivery presentation; Labor - delivery presentation; Occiput posterior; Occiput anterior; Brow presentation ... The mother can walk, rock, and try different delivery positions during labor to help encourage the baby ...

  3. Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice.

    Science.gov (United States)

    Landa, Leos; Jurica, Jan; Sliva, Jiri; Pechackova, Monika; Demlova, Regina

    2018-03-01

    The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in many aspects of its application. This mini review briefly covers the main active substances of the cannabis plant and mechanisms of action. It focuses on two conditions, cancer pain and spasticity in multiple sclerosis, where its effects are well-documented. A comprehensive overview of a few cannabis-based products and the basic pharmacokinetics of marijuana's constituents follows. The review concludes with an outline for preparing cannabis (dried inflorescence) containing drug dosage forms that can be produced in a hospital pharmacy.

  4. Premature delivery

    Directory of Open Access Journals (Sweden)

    Bernardita Donoso Bernales

    2012-09-01

    Full Text Available Preterm delivery is the single most important cause of perinatal morbidity and mortality. In Chile, preterm births have increased in the past decade, although neonatal morbidity and mortality attributable to it shows a downward trend, thanks to improvements in neonatal care of premature babies, rather than the success of obstetric preventive and therapeutic strategies. This article describes clinical entities, disease processes and conditions that constitute predisposing factors of preterm birth, as well as an outline for the prevention and clinical management of women at risk of preterm birth.

  5. Technical Requirements and Principles for the Standards Development of the Key Parts for Rotor Air-conditioning Compressors

    Institute of Scientific and Technical Information of China (English)

    Sun Min; Wen Yun; Fan Zhangzeng

    2011-01-01

    ntroductionSince 2000,air-conditioning sales continues to grow,and the development of air-conditioning market makes a booming market of compressor.At the present time,compressor production rising all the way,and the sales steps up the new steps constantly.Tendency chart is shown in figure 1.Rotor compressor with its simple structure,small volume,light weight,easy processed mechanical parts,reliable operation and other excellent characteristics occupied the dominant position in the market.Compared with reciprocating compressor on the same application situation,decreased in the size by 40%~50%,weight was reduced by 40%~50%.But there were also disadvantages,mainly large friction loss,friction power consumption was about 10%of compressor's total power input.

  6. Technical Note: Assessing predictive capacity and conditional independence of landslide predisposing factors for shallow landslide susceptibility models

    Directory of Open Access Journals (Sweden)

    S. Pereira

    2012-04-01

    Full Text Available The aim of this study is to identify the landslide predisposing factors' combination using a bivariate statistical model that best predicts landslide susceptibility. The best model is one that has simultaneously good performance in terms of suitability and predictive power and has been developed using variables that are conditionally independent. The study area is the Santa Marta de Penaguião council (70 km2 located in the Northern Portugal.

    In order to identify the best combination of landslide predisposing factors, all possible combinations using up to seven predisposing factors were performed, which resulted in 120 predictions that were assessed with a landside inventory containing 767 shallow translational slides. The best landslide susceptibility model was selected according to the model degree of fitness and on the basis of a conditional independence criterion. The best model was developed with only three landslide predisposing factors (slope angle, inverse wetness index, and land use and was compared with a model developed using all seven landslide predisposing factors.

    Results showed that it is possible to produce a reliable landslide susceptibility model using fewer landslide predisposing factors, which contributes towards higher conditional independence.

  7. The assessment of occupational protection conditions in workplaces with high levels of exposure to natural radiation. Report from a technical committee meeting. Working material

    International Nuclear Information System (INIS)

    2002-01-01

    Occupational exposure from natural radiation is, in the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) 2000 Report, estimated to contribute to more than 80 percent of the world-wide annual collective dose from occupational exposure, uranium mining excluded. The Agency's Radiation Safety Standards Series, the Requirements, and the Safety Guides (jointly sponsored by the Agency and the International Labour Office), address the control of occupational exposures from natural sources of radiation. In addition, some Safety Reports on specific issues are in the process of being finalized. Following upon recommendations to the Agency from its Member States to provide further guidance on the control of occupational exposure to natural radiation, a Technical Committee Meeting on Assessment of Occupational Radiation Protection Conditions in Workplaces with High Levels of Exposure to Natural Radiation was held in Vienna from 7 to 11 May 2001. The objective of the meeting was to produce an inventory of problem areas, make an assessment of the problem and propose a draft work plan for the Agency, This IAEA Working Material includes the report from the meeting, including the presentations made. Based on the recommendations made by the Technical Committee, a work plan is being initiated, implying that more attention will be paid to occupational exposure from natural radiation sources in the Occupational Radiation Protection programme

  8. Research on the characterization and conditioning of uranium mill tailings. II. Thermal stabilization of uranium mill tailings: technical and economic evaluation. Volume 2

    International Nuclear Information System (INIS)

    Dreesen, D.R.; Cokal, E.J.; Thode, E.F.; Wangen, L.E.; Williams, J.M.

    1983-06-01

    A method of conditioning uranium mill tailings has been devised to greatly reduce radon emanation and contaminant leachability by using high-temperature treatments, i.e., thermal stabilization. The thermally stabilized products appear resistant to weathering as measured by the effects of grinding and water leaching. The technical feasibility of the process has been partially verified in pilot-scale experiments. A conceptual thermal stabilization process has been designed and the economics of the process show that the thermal stabilization of tailings can be cost competitive compared with relocation of tailings during remedial action. The alteration of morphology, structure, and composition during thermal treatment would indicate that this stabilization method may be a long-lasting solution to uranium mill tailings disposal problems

  9. Establishment of Technical Collaboration basis between Korea and France for the development of severe accident assessment computer code under high burnup condition

    International Nuclear Information System (INIS)

    Kim, H. D.; Kim, D. H.; Park, S. Y.; Park, J. H.

    2005-10-01

    This project was performed by KAERI in the frame of construction of the international cooperative basis on the nuclear energy. This was supported from MOST under the title of 'Establishment of Technical Collaboration basis between Korea and France for the development of severe accident assessment computer code under high burn up condition'. The current operating NPP are converting the burned fuel to the wasted fuel after burn up of 40 GWD/MTU. But in Korea, burn up of more than 60 GWD/MTU will be expected because of the high fuel efficiency but also cost saving for storing the wasted fuel safely. The domestic research for the purpose of developing the fuel and the cladding that can be used under the high burn up condition up to 100 GWD/MTU is in progress now. But the current computer code adopts the model and the data that are valid only up to the 40 GWD/MTU at most. Therefore the current model could not take into account the phenomena that may cause differences in the fission product release behavior or in the core damage process due to the high burn up operation (more than 40 GWD/MTU). To evaluate the safety of the NPP with the high burn up fuel, the improvement of current severe accident code against the high burn up condition is an important research item. Also it should start without any delay. Therefore, in this study, an expert group was constructed to establish the research basis for the severe accident under high burn up conditions. From this expert group, the research items regarding the high burn up condition were selected and identified through discussion and technical seminars. Based on these selected items, the meeting between IRSN and KAERI to find out the cooperative research items on the severe accident under the high burn up condition was held in the IRSN headquater in Paris. After the meeting, KAERI and IRSN agreed to cooperate with each other on the selected items, and to co-host the international seminar, and to develop the model and to

  10. Independent technical review and analysis of hydraulic modeling and hydrology under low-flow conditions of the Des Plaines River near Riverside, Illinois

    Science.gov (United States)

    Over, Thomas M.; Straub, Timothy D.; Hortness, Jon E.; Murphy, Elizabeth A.

    2012-01-01

    The U.S. Geological Survey (USGS) has operated a streamgage and published daily flows for the Des Plaines River at Riverside since Oct. 1, 1943. A HEC-RAS model has been developed to estimate the effect of the removal of Hofmann Dam near the gage on low-flow elevations in the reach approximately 3 miles upstream from the dam. The Village of Riverside, the Illinois Department of Natural Resources-Office of Water Resources (IDNR-OWR), and the U. S. Army Corps of Engineers-Chicago District (USACE-Chicago) are interested in verifying the performance of the HEC-RAS model for specific low-flow conditions, and obtaining an estimate of selected daily flow quantiles and other low-flow statistics for a selected period of record that best represents current hydrologic conditions. Because the USGS publishes streamflow records for the Des Plaines River system and provides unbiased analyses of flows and stream hydraulic characteristics, the USGS served as an Independent Technical Reviewer (ITR) for this study.

  11. Technical and biological evaluation of Galician carp young-of-the-year in the conditions of industrial rearing in the ponds of Subcarpathia

    Directory of Open Access Journals (Sweden)

    I. Hrytsyniak

    2017-03-01

    Full Text Available Purpose To analyze technical and biological parameters of Galician carp young-of-the-year in the conditions of their commercial rearing in Subcarpathia ponds. Methodology. The works have been performed in accordance with conventional techniques in fish farming and selective breeding. During the rearing of Galician carp yearlings, a monitoring of abiotic factors in the experimental pond has been carried out. Findings. According to hydrochemical analysis, pond water belonged to hydrocarbonate class of calcium water and a type, which is typical for natural waters of this physical-geographic area. The species composition of phytoplankton at the beginning of the study was represented by 39 species and intraspecific taxa, in the middle of the experiment — 33, and 36 species and intraspecific taxa at the end of the study period. The majority of phytoplankton species composition was represented by green algae. The majority of zooplankton biomass (up 46% was represented by copepods, while rotifers dominated by abundance (up 49.9%. The parameters of zoobenthos development in the rearing pond ranged within 54 - 120 ind. / m2 by abundance and 0.5 - 1.3 g / m2 by biomass. The most abundant zoobenthic organisms were Chironomidae (71% and Oligochaeta (29%. Fish stocking density in the rearing pond of the 1st order was 10 thousand fish/ha; fish seeds were represented by Galician carp larvae. At the end of the growing season, 27.2 thousand young-of-the-year were obtained, the survival rate was 68%. Mean individual weight was 96 ± 75 g, coefficient of variation was 12%. When assessing the dynamics of weight growth, its peak was observed in the first week of August, while the specific growth rate had maximum values in the third week of July. Exterior parameters were used to evaluate strain characteristics. In the middle of the growing season, the young-of-the-year had mean condition factor of 2.6 ± 0.3, which was high enough for them. Before wintering, this

  12. Barriers and prospects of India's conditional cash transfer program to promote institutional delivery care: a qualitative analysis of the supply-side perspectives.

    Science.gov (United States)

    Gupta, Adyya; Fledderjohann, Jasmine; Reddy, Hanimi; Raman, V R; Stuckler, David; Vellakkal, Sukumar

    2018-01-25

    Under the National Health Mission (NHM) of India, Janani Suraksha Yojana (JSY) offers conditional cash transfer and support services to pregnant women to use institutional delivery care facilities. This study aims to understand community health workers' (ASHAs) and program officials' perceptions regarding barriers to and prospects for the uptake of facilities offered under the JSY. Fifty in-depth interviews of a purposively selected sample of ASHAs (n = 12), members of Village Health and Sanitation Committees (n = 11), and officials at different tiers of healthcare facilities (n = 27) were conducted in three Indian states. The data were analyzed thematically using ATLAS.ti software. Although the JSY has triggered considerable advancement on the Indian maternal and child health front, there are several barriers to be resolved pertaining to i) delivering quality care at health-facility; ii) linkages between home and health-facility; and iii) the community/household context. At the facility level, respondents cited an inability to treat birth complications as a barrier to JSY uptake, resulting in referrals to other (mostly private) facilities. Despite increased investment in health infrastructure under the program, shortages in emergency obstetric-care facilities, specialists and staff, essential drugs, diagnostics, and necessary equipment persisted. Weaker linkages between various vertical (standalone) elements of maternal and primary healthcare programs, and nearly uniform resource allocation to all facilities irrespective of caseloads and actual need also constrained the provision of quality healthcare. Barriers affecting the linkages between home and facility arose mainly due to the mismatch between the multiple demands and the availability of transport facilities, especially in emergency situations. Regarding community/household context, several socio-cultural issues such as resistance towards the ASHA's efforts of counselling, particularly from

  13. Technical and economic analysis of grid-connected PV/Wind energy stations in the Republic of Serbia under varying climatic conditions

    OpenAIRE

    Bakić, Vukman V.; Pezo, Milada L.; Stojković, Saša M.

    2016-01-01

    In this paper technical and economic analysis of grid-connected PV/Wind energy systems located in the Republic of Serbia are presented. The technical and economic data, of the various grid-connected PV/Wind hybrid energy systems for three different locations: Novi Sad, Belgrade and Kopaonik, using the transient simulations software TRNSYS and HOMER were obtained. The results obtained in this paper show that locations and technical characteristics of the energy systems have an important influe...

  14. Assessing the damage importance rank in acoustic diagnostics of technical conditions of the internal combustion engine with multi-valued logical decision trees

    Directory of Open Access Journals (Sweden)

    Deptuła Adam

    2017-01-01

    Full Text Available This paper presents possible applications of acoustic diagnostics in inspecting the technical condition of an internal combustion engine with autoignition on the example of the Fiat drive unit with the common rail system. As a result of measuring the sound pressure level for specific faults and comparing the noise generated by the motor running smoothly, the detailed maps of changes in the acoustic spectrum may be generated. These results may be helpful in future diagnostics of internal combustion engines. In the paper, we present the results from the scientific works in the area of research, design and operation of internal combustion engines, conducted at the Department of Automotive Engineering, in cooperation with the Laboratory of Hydraulic Drives & Vibroacoustics of Machines at the Wroclaw University of Technology. The broader study has so far allowed us to develop an authoritative method of identifying the type of engine damage using gametree structures. The present works assess the possibility of using multi-valued logic trees.

  15. Measurements of lateral penumbra for uniform scanning proton beams under various beam delivery conditions and comparison to the XiO treatment planning system

    International Nuclear Information System (INIS)

    Rana, Suresh; Zeidan, Omar; Ramirez, Eric; Rains, Michael; Gao, Junfang; Zheng, Yuanshui

    2013-01-01

    Purpose: The main purposes of this study were to (1) investigate the dependency of lateral penumbra (80%–20% distance) of uniform scanning proton beams on various factors such as air gap, proton range, modulation width, compensator thickness, and depth, and (2) compare the lateral penumbra calculated by a treatment planning system (TPS) with measurements.Methods: First, lateral penumbra was measured using solid–water phantom and radiographic films for (a) air gap, ranged from 0 to 35 cm, (b) proton range, ranged from 8 to 30 cm, (c) modulation, ranged from 2 to 10 cm, (d) compensator thickness, ranged from 0 to 20 cm, and (e) depth, ranged from 7 to 15 cm. Second, dose calculations were computed in a virtual water phantom using the XiO TPS with pencil beam algorithm for identical beam conditions and geometrical configurations that were used for the measurements. The calculated lateral penumbra was then compared with the measured one for both the horizontal and vertical scanning magnets of our uniform scanning proton beam delivery system.Results: The results in the current study showed that the lateral penumbra of horizontal scanning magnet was larger (up to 1.4 mm for measurement and up to 1.0 mm for TPS) compared to that of vertical scanning magnet. Both the TPS and measurements showed an almost linear increase in lateral penumbra with increasing air gap as it produced the greatest effect on lateral penumbra. Lateral penumbra was dependent on the depth and proton range. Specifically, the width of lateral penumbra was found to be always lower at shallower depth than at deeper depth within the spread out Bragg peak (SOBP) region. The lateral penumbra results were less sensitive to the variation in the thickness of compensator, whereas lateral penumbra was independent of modulation. Overall, the comparison between the results of TPS with that of measurements indicates a good agreement for lateral penumbra, with TPS predicting higher values compared to

  16. Technical writing versus technical writing

    Science.gov (United States)

    Dillingham, J. W.

    1981-01-01

    Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

  17. The impact of technical conditions of X-ray imaging on reproducibility and precision of digital computer-assisted X-ray radiogrammetry (DXR)

    International Nuclear Information System (INIS)

    Malich, A.; Boettcher, J.; Pfeil, A.; Sauner, D.; Heyne, J.P.; Petrovitch, A.; Hansch, A.; Kaiser, W.A.; Linss, W.

    2004-01-01

    To evaluate the reproducibility of imaging and analysis for bone mineral density (BMD) determination using digital computer-assisted X-ray radiogrammetry (DXR; Pronosco X-posure, version V.2, Sectra Pronosco, Denmark); to verify potential factors that influence BMD extrapolation such as tube voltage, film-focus distance (FFD), film quality and brand (Kodak T-MAT-Plus, Konika SRH, Agfa Scopix), imaging technology (conventional, digital), imaging system (Kodak, Agfa) and exposure level (mAs); and to clarify whether DXR analysis based on printouts of digital images is comparable to analysis of conventional images. The hand of a cadaver was X-rayed using varied parameters: 4-8 mAs, 40-52 kV, 90-130 cm FFD. Radiographs under standardised conditions were performed 10 times using a conventional machine (Philips Super 80 CP) and the printouts of a digital system (Digital Diagnost Philips Optimus) for the analysis of reproducibility. One image was scanned and analysed 10 times additionally for imaging reproducibility. Reliability error of the system for the imaging process using conventional radiographs-rays was 0.49% (standard conditions: 6 mAs, 40 kV, 1 m FFD), using printouts of digital images was 2.89% (4 mAs, 42 kV, 1 m FFD) and regarding the analysis process was 0.22%. BMD calculation is not affected by alterations in FFD (precision error 1.21%), mAs (0.83%) or film quality/brand (0.38%), but differs significantly depending on tube voltage (2.70%). The system was not able to analyse conventional images with tube voltages of 49/52 kV. DXR technology is stable with most of the tested parameters. Normative data should exclusively be used for calculations using similar tube voltage or correction factors. All other parameters had no significant influence on the BMD calculation. Reproducibility is high. For technical reasons it is not recommended to use the printouts of digital images for BMD determination. (orig.)

  18. After Delivery

    Science.gov (United States)

    ... Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & Fitness Home Food MyFoodAdvisor ... A Listen En Español After Delivery After your baby arrives, your body begins to recover from the ...

  19. An approach to communications security for a communications data delivery system for V2V/V2I safety : technical description and identification of policy and institutional issues.

    Science.gov (United States)

    This report identifies the security approach associated with a communications data delivery system that supports vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications. The report describes the risks associated with communication...

  20. Imagining Technicities

    DEFF Research Database (Denmark)

    Liboriussen, Bjarke; Plesner, Ursula

    2011-01-01

    to the elements of taste and skill. In the final analysis those references were synthesized as five imagined technicities: the architect, the engineer, the client, the Chinese, and the Virtual World native. Because technicities are often assumed and rarely discussed as actants who influence practice, their role......, this article focuses on innovative uses of virtual worlds in architecture. We interviewed architects, industrial designers and other practitioners. Conceptually supported by an understanding of technicity found in Cultural Studies, the interviews were then coded with a focus on interviewees’ references...... in cooperation and development of ICTs seems to pass unnoticed. However, since they are aligned into ICTs, technicities impact innovation....

  1. Comparative analysis of the efficiency, reliability, technical feasibility and costs of methods to convert sewage sludge to a hygienically safe condition

    International Nuclear Information System (INIS)

    Fuhrmann, D.; Leschber, R.; Mueller, G.; Jaeger, B.; Neumann, U.

    1981-01-01

    Due to the development of sewage treatment technology and the construction of new and sewage works and enlargement of older ones, increasing amounts of sewage sludge have been produced. Agricultural use of municipal sewage sludge is a practicable way of utilization which, however, is often limited for reasons of hygienic safety. The present study intends to describe methods of sewage sludge disinfection which have been used in practice or tested extensively, as well as technical innovations in this field, and to give information on their performance with respect to hygienic and technical requirements. A direct comparison of processes has turned out to be extremely difficult because disinfection of sewage sludge is only one of the stages of sewage treatment. For comparison, numerous factors have to be taken into account such as plant size, type of sewage and sludge treatment processes, energy costs, sales potential for agricultural use etc. This study is meant as an aid in such work. (orig.) [de

  2. Controlled iontophoretic transport of huperzine A across skin in vitro and in vivo: effect of delivery conditions and comparison of pharmacokinetic models.

    Science.gov (United States)

    Kalaria, Dhaval R; Patel, Pratikkumar; Merino, Virginia; Patravale, Vandana B; Kalia, Yogeshvar N

    2013-11-04

    The aim of this study was to investigate constant current anodal iontophoresis of Huperzine A (HupA) in vitro and in vivo and hence to evaluate the feasibility of using electrically assisted delivery to administer therapeutic amounts of the drug across the skin for the treatment of Alzheimer's disease. Preliminary experiments were performed using porcine and human skin in vitro. Stability studies demonstrated that HupA was not degraded upon exposure to epidermis or dermis for 12 h and that it was also stable in the presence of an electric current (0.5 mA · cm(-2)). Passive permeation of HupA (2 mM) was minimal (1.1 ± 0.1 μg · cm(-2)); iontophoresis at 0.15, 0.3, and 0.5 mA · cm(-2) produced 106-, 134-, and 184-fold increases in its transport across the skin. Surprisingly, despite the use of a salt bridge to isolate the formulation compartment from the anodal chamber, which contained 133 mM NaCl, iontophoresis of HupA was shown to increase linearly with its concentration (1, 2, and 4 mM in 25 mM MES, pH 5.0) (r(2) = 0.99). This was attributed to the low ratio of drug to Cl¯ (in the skin and in the receiver compartment) which competed strongly to carry current, its depletion, and to possible competition from the zwitterionic MES. Co-iontophoresis of acetaminophen confirmed that electromigration was the dominant electrotransport mechanism. Total delivery across human and porcine skin was found to be statistically equivalent (243.2 ± 33.1 and 235.6 ± 13.7 μg · cm(-2), respectively). Although the transport efficiency was ∼ 1%, the iontophoretic delivery efficiency (i.e., the fraction of the drug load delivered) was extremely high, in the range of 46-81% depending on the current density. Cumulative permeation of HupA from a Carbopol gel formulation after iontophoresis for 6 h at 0.5 mA · cm(-2) was less than that from solution (135.3 ± 25.2 and 202.9 ± 5.2 μg · cm(-2), respectively) but sufficient for therapeutic delivery. Pharmacokinetic parameters were

  3. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2012-01-01

      UXC + detectors As explained in detail in the November 2011 bulletin, the bellows unit at −18.5 m from the CMS interaction point was identified as a prime candidate for the regularly occurring pressure spikes which occasionally led to sustained severe background conditions in 2011, affecting dead time and data quality. Similar regions in LHC with vacuum instabilities were observed to be close to bellows, which radiography showed to have distorted RF-fingers — on removal, they proved to have been severely overheated. The plans for the Year-End Technical Stop were adapted to prioritise radiography of the bellows at 16 m to 18 m either end of CMS. Excellent work by the beam pipe, survey and heavy mechanical teams allowed the X-rays to be taken as planned on 20th December, showing that the bellow at −18.5m had an obvious non-conformity. The RF-fingers were found inside the end of the opposing flared pipe instead of outside. In addition, the overlap between fingers and...

  4. Using transdermal iontophoresis to increase granisetron delivery across skin in vitro and in vivo: effect of experimental conditions and a comparison with other enhancement strategies.

    Science.gov (United States)

    Cázares-Delgadillo, Jennyfer; Ganem-Rondero, Adriana; Quintanar-Guerrero, David; López-Castellano, Alicia C; Merino, Virginia; Kalia, Yogeshvar N

    2010-03-18

    The objectives of the study were (i) to investigate the effect of experimental parameters on the iontophoretic transport of granisetron, (ii) to identify the relative contributions of electromigration (EM) and electroosmosis (EO), (iii) to determine the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting and (iv) to test the in vitro results in a simple animal model in vivo. Preliminary in vitro studies using aqueous granisetron formulations investigating the effect of drug concentration (5, 10, 20 and 40 mM) and current density (0.1, 0.2, 0.3 mA cm(-2)) were performed using porcine ear skin. As expected, cumulative delivery in vitro at the 20 and 40 mM concentrations was significantly greater than that at 5 and 10mM, which were not statistically different (pgranisetron concentration of 40 mM, the transport rate was 2.93+/-0.62 microg cm(-2)min(-1)). Co-iontophoresis of acetaminophen was used to show that EM was the predominant transport mechanism accounting for 71-86% of total granisetron delivery. In vivo studies in Wistar rats (40 mM granisetron; application of 0.3 mA cm(-2) for 5h with Ag/AgCl electrodes and salt bridges) showed an average iontophoretic input rate (k(input)) of 0.83+/-0.26 microg min(-1) and a maximum plasma concentration (C(max)) of 0.092+/-0.004 microg ml(-1). Based on these results and given the known pharmacokinetics, transdermal iontophoresis could achieve therapeutic drug levels for the management of chemotherapy-induced emesis using a reasonably sized (4-6 cm(2)) patch. Copyright 2010 Elsevier B.V. All rights reserved.

  5. Handling, conditioning and storage of spent sealed radioactive sources. Technical manual for the management of low and intermediate level wastes generated at small nuclear research centres and by radioisotope users in medicine, research and industry

    International Nuclear Information System (INIS)

    2000-05-01

    This report is intended to provide reference material, guidance and know-how on handling, conditioning and storage of spent sealed radioactive sources (SRS) to both users of SRS and operators of waste management facilities. The scope of this report covers all types of SRS except those exempted from regulatory control. The report contains in some detail technical procedures for the conditioning of spent SRS, describes the means required to assure the quality of the resulting package and discusses the measures to prepare waste packages with a certain flexibility to accommodate possible future disposal requirements

  6. Levels of serum-circulating angiogenic factors within 1 week prior to delivery are closely related to conditions of pregnant women with pre-eclampsia, gestational hypertension, and/or fetal growth restriction.

    Science.gov (United States)

    Nanjo, Sakiko; Minami, Sawako; Mizoguchi, Mika; Yamamoto, Madoka; Yahata, Tamaki; Toujima, Saori; Shiro, Michihisa; Kobayashi, Aya; Muragaki, Yasuteru; Ino, Kazuhiko

    2017-12-01

    We aimed to investigate maternal serum angiogenic marker profiles within 1 week prior to delivery in cases of gestational hypertension (GH), pre-eclampsia (PE), and/or fetal growth restriction (FGR) with different clinical conditions. We enrolled 165 women with singleton pregnancy. The participants were classified based on three characteristics: (i) proteinuria (GH and PE); (ii) FGR (PE with FGR [PE + FGR], PE alone, and FGR alone); and (iii) onset (early onset PE [EO PE] and late-onset PE [LO PE]). All sera were obtained within 1 week prior to delivery, and soluble fms-like tyrosine kinase 1 (sFlt-1), soluble endoglin (sEng), and placental growth factor (PlGF) were measured with enzyme-linked immunosorbent assay. (i) In PE, a significantly increased sFlt-1, sEng, and sFlt-1 to PlGF ratio (sFlt-1/PlGF) and significantly decreased PlGF were observed compared with GH and Term control, whereas in GH, only sFlt-1/PlGF was significantly higher than Term control. (ii) In PE + FGR, similar changes were more markedly shown compared with PE alone. The FGR alone group exhibited similar tendencies as PE, although significant differences were found in PlGF and sEng levels. (iii) In EO PE, significant changes were observed in all factors compared with LO PE or Term control, while no significant change in PlGF levels was observed between LO PE and Term control. We demonstrated that the levels of circulating angiogenic factors just before delivery are correlated with the severity of hypertensive disorders of pregnancy and FGR. Profiling these specific markers may contribute to better understanding of the clinical conditions in individual patients and their pathogenesis. © 2017 Japan Society of Obstetrics and Gynecology.

  7. Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Jonathan D. Istok

    2008-06-01

    ‘Bioimmobilization’ of redox-sensitive metals and radionuclides is being investigated as a way to remediate contaminated groundwater and sediments. In this approach, growth-limiting substrates are added to stimulate the activity of targeted groups of indigenous microorganisms and create conditions favorable for the microbially-mediated precipitation (‘bioimmobilization’) of targeted contaminants. This project investigated a fundamentally new approach for modeling this process that couples thermodynamic descriptions for microbial growth with associated geochemical reactions. In this approach, a synthetic microbial community is defined as a collection of defined microbial groups; each with a growth equation derived from bioenergetic principles. The growth equations and standard-state free energy yields are appended to a thermodynamic database for geochemical reactions and the combined equations are solved simultaneously to predict the effect of added substrates on microbial biomass, community composition, and system geochemistry. This approach, with a single set of thermodynamic parameters (one for each growth equation), was used to predict the results of laboratory and field bioimmobilization experiments at two geochemically diverse research sites. Predicted effects of ethanol or acetate addition on uranium and technetium solubility, major ion geochemistry, mineralogy, microbial biomass and community composition were in general agreement with experimental observations although the available experimental data precluded rigorous model testing. Model simulations provide insight into the long-standing difficulty in transferring experimental results from the laboratory to the field and from one field site to the next, especially if the form, concentration, or delivery of growth substrate is varied from one experiment to the next. Although originally developed for use in better understanding bioimmobilization of uranium and technetium via reductive precipitation

  8. Technical and energy economic boundary conditions for a CCS based power generation structure in Europe; Technische und energiewirtschaftliche Rahmenbedingungen fuer eine CCS-basierte Erzeugungsstruktur in Europa

    Energy Technology Data Exchange (ETDEWEB)

    Kober, Tom; Blesl, Markus [Stuttgart Univ. (Germany). Inst. fuer Energiewirtschaft und Rationelle Energieanwendung

    2008-07-01

    The development of the power generation in Europe substantially is characterized by the process of liberalisation and the endeavours to climate protection. The ensuring of future supply security increasingly becomes more important. In order to achieve the climatic protection goal a multiplicity of technical options in the competitively organized market is available. In order to be competitive in such a market, certain requirements have to be expected to future power plants with CCS technology (CCS = carbon Capture and storage). By means of a European energy system model the question is to answered in the contribution under consideration which requirements to the CS technology have to be expected to the CCS technology.

  9. Research Plan: Foam Delivery of Remedial Amendments to Deep Vadose Zone for Metals and Radionuclides Remediation

    International Nuclear Information System (INIS)

    Zhong, Lirong; Hart, Andrea T.; Szecsody, James E.; Zhang, Z.F.; Freedman, Vicky L.; Ankeny, Mark; Hull, Laurence; Oostrom, Martinus; Freshley, Mark D.; Wellman, Dawn M.

    2009-01-01

    Research proposals were submitted to the Scientific and Technical Basis for In Situ Treatment of Metals and Radionuclides Technical Working Group under the US Department of Energy (DOE) Environmental Management Office (specifically, EM-22). After a peer review and selection process, the proposal, 'Foam Delivery of Remedial Amendments to Deep Vadose Zone for Metals and Radionuclides Remediation,' submitted by Pacific Northwest National Laboratory (PNNL) was selected for support by the program. A research plan was requested for this EM funded project. The overall objective of this project is to develop foam delivery technology for the distribution of remedial amendments to deep vadose zone sediments for in situ immobilization of metal and radionuclide contaminants. The focus of this research in FY 2009 is on the physical aspects of the foam delivery approach. Specific objectives are to (1) study the foam quality (i.e. the gas volume fraction in foam) influence on injection pressure, (2) study the sediment air permeability influence on injection pressure, (3) investigate liquid uptake in sediment and determine whether a water front will be formed during foam delivery, (4) test amendment distance (and mass) delivery by foam from the injection point, (5) study the enhanced sweeping over heterogeneous systems (i.e., low K zones) by foam delivery relative to water-based delivery under vadose zone conditions, and (6) numerically simulate foam delivery processes in the vadose zone. Laboratory scale experiments will be conducted at PNNL to study a range of basic physical aspects of the foam propagation in sediments, including foam quality and sediment permeability influence on injection pressure, liquid uptake, and foam sweeping across heterogeneous systems. This study will be augmented with separate studies to be conducted at MSE Technology Applications, Inc. (MSE) to evaluate foam transport and amendment delivery at the intermediate-scale. The results of intermediate

  10. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimize the management of the Technical Network (TN), to ease the understanding and purpose of devices connected to the TN, and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive email notifications from IT/CS asking them to add the corresponding information in the network database. Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  11. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimise the management of the Technical Network (TN), to facilitate understanding of the purpose of devices connected to the TN and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive e-mails from IT/CS asking them to add the corresponding information in the network database at "network-cern-ch". Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  12. Phytase application in chewing gum - A technical assessment

    DEFF Research Database (Denmark)

    Nielsen, Anne Veller Friis; Meyer, Anne S.

    2016-01-01

    either prior to ingestion, i.e. in the food, or post ingestion, i.e. in the human gastrointestinal tract. We have assessed the technical aspects of formulation and release of phytase added to chewing gum as a delivery vehicle. Phytases from Aspergillus niger and Escherichia coli incorporated into chewing...... gum were released quantitatively upon chewing and retained phytase activity (50-80% of the enzyme activity added was released within 10 minutes). Initial evaluations of phytase chewing gum shelf life showed good stability after 48 days of storage of the chewing gum at ambient conditions....

  13. Assisted Vaginal Delivery

    Science.gov (United States)

    ... Education & Events Advocacy For Patients About ACOG Assisted Vaginal Delivery Home For Patients Search FAQs Assisted Vaginal ... Vaginal Delivery FAQ192, February 2016 PDF Format Assisted Vaginal Delivery Labor, Delivery, and Postpartum Care What is ...

  14. The main altarpiece of Our Lady of the Elms church in Torre de Juan Abad, Spain: technical study and condition state

    Directory of Open Access Journals (Sweden)

    Rosario Llamas

    2013-01-01

    Full Text Available The altarpiece of the church of Our Lady of the Elms, in Campo de Montiel, attributed to Francisco Cano, is a unique masterpiece that represents the essence of the Mannerism or Late Renaissance in the region. Its technical study is one of the objectives of this article that seeks to explain the constructive aspects and identify the materials (wood species, pigments and binders and the techniques used. Simultaneously, we have characterized its current state of preservation, describing in detail the problems identified, both structurally and in terms of the polychromy. We have tried to revalue an important work that got to survive the events of the Spanish Civil War. Generally speaking, it is unpublished information that has been collected and presented here.

  15. Physico technical conditions of X-ray study on the Russian X-ray diagnostic complexes Medics-R and Telemedics-R

    International Nuclear Information System (INIS)

    Blinov, N.N.; Blinov, N.M. ml

    1999-01-01

    The exposure tables developed on the basis of technical tests and experience in applying new foreign X-ray films in combination with the national calcium-tungstate (TIS) and yttrium (YIS) intensification screens are proposed for the purpose of establishing the image electrical parameters (voltage and the X-ray tube current, exposure time) by certain geometry of the roentgenological study at the Medics-R and Telemedics-R complexes (focus, focal distance, raster-, screen- and film type). The difference in the screens sensitivity by work with the green-sensitive films depending on the anode voltage applied constitutes 2.5 (40-60 kV) up to 1.8 (above 60 kV). Attention is also paid to application of automatic means [ru

  16. Classified directory of the field of refrigeration and air conditioning technology 2006. Register of the expert companies in the field of refrigeration and air conditioning plants craft including a supply and service list - register of the suppliers in the field of refrigeration and air conditioning technology including the complete ranges of material groups offered - register of expert schools, technical experts, technical expert information and norms; Branchenbuch der Kaelte- und Klimatechnik 2006. Verzeichnis der Fachbetriebe des Kaelte- und Klimaanlagenbauerhandwerks mit Liefer- und Leistungsangebot - Verzeichnis der Lieferanten von Kaelte- und Klimatechnik mit vollstaendigem Warengruppenangebot - Verzeichnis von Fachschulen, Sachverstaendigen u.v.a. - Technische Fachinformationen und Normen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The present edition of the ''Classified directory of the field of refrigeration and air conditioning technology'' 2006 contains useful addresses, data and facts of the field: (a) approximately 1.500 addresses of expert companies in the field of refrigeration and air conditioning technology; (b) a register of suppliers and material groups in the field of refrigeration and air conditioning technology; (c) a technical part containing the most important norms of the field, laws and regulations in order to inform the reader for his daily work. The reference book is supposed to provide a good overview for the work in the field of technical building equipment. (orig./AKF)

  17. Investigation of the particle size distribution and particle density characteristics of Douglas fir hogged fuel fly ash collected under known combustion conditions. Technical Progress Report No. 2

    Energy Technology Data Exchange (ETDEWEB)

    Lang, A.J.; Junge, D.C.

    1978-12-01

    The increased interest in wood as a fuel source, coupled with the increasing demand to control the emission generated by wood combustion, has created a need for information characterizing the emissions that occur for given combustion conditions. This investigation characterizes the carbon char and inorganic fly ash size and density distribution for each of thirty-eight Douglas fir bark samples collected under known conditions of combustion.

  18. The story of technical cooperation

    International Nuclear Information System (INIS)

    Park, Yang Taek

    1989-09-01

    This book gives descriptions of technical cooperation, which is about why does technology transfer?, process of technology transfer with model, decisive cause and cooperation of technology transfer, cost and effect of technology transfer, historical experience of technology transfer, cases of technology transfer by field such as rubber tire, medicine and computer industry and automobile industry, technology transfer process and present condition of technical cooperation, and strategy for rising of technical cooperation : selection of technology for object of cooperation and development of human resources.

  19. Technical Summary

    NARCIS (Netherlands)

    Arvizu, D.; Faaij, A.P.C.

    2011-01-01

    All societies requir e energy services to meet basic human needs (e.g., lighting, cooking, space comfort, mobility, communication) and to serve productive processes. For development to be sustainable, delivery of energy services needs to be secure and have low environmental impacts. Sustainable

  20. Management of technical information department

    Energy Technology Data Exchange (ETDEWEB)

    Kim, T H; Han, D H; Moon, H W [and others

    1997-03-01

    This report introduces technical information activities in 1996. They are composed of basic tasks and applied tasks. 1. Basic activities - acquisition, cataloging, and Information services 2. Management of KAERI-TIPS (Technical Information Processing System) 3. Construction of the database for nuclear-related Information 4. Role of Specialized Nuclear Information Center in the field of nuclear energy and cooperation with INIS section of IAEA 5. Beside above activities, in 1996 TID homepage was opened and online document delivery service was provided. (author). 25 tabs., 17 figs.

  1. Management of technical information department

    International Nuclear Information System (INIS)

    Kim, T. H.; Han, D. H.; Moon, H. W.

    1997-03-01

    This report introduces technical information activities in 1996. They are composed of basic tasks and applied tasks. 1. Basic activities - acquisition, cataloging, and Information services 2. Management of KAERI-TIPS (Technical Information Processing System) 3. Construction of the database for nuclear-related Information 4. Role of Specialized Nuclear Information Center in the field of nuclear energy and cooperation with INIS section of IAEA 5. Beside above activities, in 1996 TID homepage was opened and online document delivery service was provided. (author). 25 tabs., 17 figs

  2. Forecasts of forest conditions in regions of the United States under future scenarios: a technical document supporting the Forest Service 2012 RPA Assessment

    Science.gov (United States)

    David N. Wear; Robert Huggett; Ruhong Li; Benjamin Perryman; Shan Liu

    2013-01-01

    The 626 million acres of forests in the conterminous United States represent significant reserves of biodiversity and terrestrial carbon and provide substantial flows of highly valued ecosystem services, including timber products, watershed protection benefits, and recreation. This report describes forecasts of forest conditions for the conterminous United States in...

  3. The Maintenance of Heating, Ventilating and Air-Conditioning Systems and Indoor Air Quality in Schools: A Guide for School Facility Managers. Technical Bulletin.

    Science.gov (United States)

    Wheeler, Arthur E.

    To help maintain good indoor air quality (IAQ) in schools, guidance for the development and implementation of an effective program for maintenance and operation of heating, ventilating, and air-conditioning (HVAC) systems are discussed. Frequently, a building's occupants will complain about IAQ when the temperature or humidity are at uncomfortable…

  4. Decree no. 2009-959 from July 29 2009 relative to some technical conditions of operation to be applied in cancer treatment activity

    International Nuclear Information System (INIS)

    2009-08-01

    This decree aims at making compulsory the presence of a skilled medical radio-physics specialist in the medical centre during the whole duration of the radiotherapy treatment given to patients. The planning of presence of this specialist must take into account the schedule of patients treatment. The decree specifies the conditions of deputizing in case of absence of this specialist. (J.S.)

  5. Treatment of Children with Protein – Losing Enteropathy After Fontan and Other Complex Congenital Heart Disease Procedures in Condition with Limited Human and Technical Resources

    Science.gov (United States)

    Bejiqi, Ramush; Retkoceri, Ragip; Zeka, Naim; Bejiqi, Hana; Vuqiterna, Armend; Maloku, Arlinda

    2014-01-01

    Background Protein-losing enteropathy (PLE) is a disorder characterized by abnormal and often profound enteric protein loss. It’s relatively uncommon complication of Fontan and other complex congenital heart disease (CCHD) procedures. Because of the complexity and rarity of this disease process, the pathogenesis and pathophysiology of protein-losing enteropathy remain poorly understood, and attempts at treatment seldom yield long-term success. Aim of presentation is to describe single centre experience in diagnosis, evaluation, management and treatment of children with protein-losing enteropathy after Fontan and other CCHD procedures in the current era and in centre with limited human and technical resources, follows with a comprehensive review of protein-losing enteropathy publications, and concludes with suggestions for prevention and treatment. Material and methodology Retrospectively we analyzed patients with CCHD and protein-losing enteropathy in our institution, starting from January 2000 to December 2012. The including criteria were age between two and 17 years, to have a complex congenital heart disease and available complete documentation of cardiac surgery under cardiopulmonary bypass. Results Of all patients we evaluated 18 cases with protein-losing enteropathy, aged 6 to 19 years (mean 14±9); there were three children who had undergone screening procedure for D-transposition, one Tetralogy of Fallot, and remaining 14 patients had undergone Fontan procedures; (anatomic diagnosis are: six with tricuspid atresia, seven with d-transposition, double outlet right ventricle and pulmonary atresia and two with hypoplastic left heart syndrome). The diagnosis of protein-losing enteropathy was made at median age of 5.6 years, ranging from 13 months to 15 years. Diagnosis was made using alpha 1-antitrypsin as a gold marker in stool. By physical examination in 14 patients edema was found, in three ascites, and six patients had pleural effusion. Laboratory findings

  6. Computational modeling and experimental studies on NO{sub x} reduction under pulverized coal combustion conditions. Third quarterly technical progress report, July 1, 1995--September 30, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Kumpaty, S.K.; Subramanian, K.

    1995-12-31

    An experimental plan outlining the first year`s activity was sent to Dr. Lori Gould, Project Officer/Contracting Officer`s Technical Representative on April 24, 1995. An approval was received with some questions on June 15, 1995. However, with some foresight of the director of the in-house combustion group of the PETC, Dr. Ekmann, a tentative hold-off on the purchase of the equipment was requested by the project officer on June 29, 1995. Enclosed with that request were some of Dr. Ekmann`s concerns. The research team spent the month of July in study of pertinent literature as well as in the preparation of the responses to Dr. Gould`s comments and Dr. Ekmann`s concerns. These responses included the choice of the reactor, reactor design, rate of gas heating, detailed test matrix and answers to host of other comments. Upon review of the above information submitted on July 24, 1995 by the Rust research team, the project officer called for a conference call on September 6, 1995 which involved the PI (Dr. Kumpaty), the research consultant (Mr. Subramanian), Dr. Gould and Dr. Ekmann. Dr. Ekmann insisted that further calculations be made on the rate of gas heating without taking radiation into account. Accordingly, calculations pertaining to the rate of gas heating based on convection were performed and submitted to Dr. Ekmann on September 13, 1995. This report contains the information emerged through the dialogue between the Rust College research team and the PETC represented by Dr. Gould and Dr. Ekmann during this quarter.

  7. Technical Note

    African Journals Online (AJOL)

    Administratör

    In this report on four patients, we did not use any of these techniques. The existence and the site of the fistulas was clearly demonstrated using basic but important preoperative detailed assessment and two intraoperative findings. The preoperative referral note that indicated the site of technical difficulty during the previous ...

  8. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience At the end of the first full-year running period of LHC, CMS is established as a reliable, robust and mature experiment. In particular common systems and infrastructure faults accounted for <0.6 % CMS downtime during LHC pp physics. Technical operation throughout the entire year was rather smooth, the main faults requiring UXC access being sub-detector power systems and rack-cooling turbines. All such problems were corrected during scheduled technical stops, in the shadow of tunnel access needed by the LHC, or in negotiated accesses or access extensions. Nevertheless, the number of necessary accesses to the UXC averaged more than one per week and the technical stops were inevitably packed with work packages, typically 30 being executed within a few days, placing a high load on the coordination and area management teams. It is an appropriate moment for CMS Technical Coordination to thank all those in many CERN departments and in the Collaboration, who were involved in CMS techni...

  9. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience Since the closure of the detector in February, the technical operation of CMS has been quite smooth and reliable. Some minor interventions in UXC were required to cure failures of power supplies, fans, readout boards and rack cooling connections, but all these failures were repaired in scheduled technical stops or parasitically during access dedicated to fixing LHC technical problems. The only occasion when CMS had to request an access between fills was to search for the source of an alarm from the leak-detection cables mounted in the DT racks. After a few minutes of diagnostic search, a leaking air-purge was found. Replacement was complete within 2 hours. This incident demonstrated once more the value of these leak detection cables; the system will be further extended (during the end of year technical stop) to cover more racks in UXC and the floor beneath the detector. The magnet has also been operating reliably and reacted correctly to the 14s power cut on 29 May (see below). In or...

  10. Technical endoscopy

    International Nuclear Information System (INIS)

    Cavalar, K.O.

    1988-01-01

    A survey is provided on different versions of endoscopes, taking into account the new developments of video endoscopy. With a variety of practical examples it is shown that technical tests using endoscopy are a demanding task for nondestructive testing, whose requirements can only be met on a customized basis. (orig./HP) [de

  11. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Monday 9 February 2004 From 10:00 to 12:00 - IT Auditorium - bldg. 31, 3rd floor ANSOFT High-Frequency Seminar David Prestaux, Application Engineer, ANSOFT F-78535 BUC, France This Technical Training seminar will present two Ansoft application products: Ansoft HFSS and Ansoft Designer. Ansoft HFSS makes use of the Finite Element Method (FEM) to calculate field solutions from first principles. It can accurately predict all high-frequency behaviours such as dispersion, mode conversion, and losses due to materials and radiation. Ansoft Designer is a suite of design tools to fully integrate high-frequency, physics-based electromagnetic simulations into a seamless system-level simulation environment. Ansoft Designer uses a simple interface to give complete control over every design task, by a method allowing multiple solvers, Solver on Demand. • Introduction • Overview of the Ansoft Total solution • Ansoft HFSS 9...

  12. Technical specifications for waste packages conditioned in a durable confining shell, with an hydraulic binder basis, intended to a ground disposal site

    International Nuclear Information System (INIS)

    1995-06-01

    The aim of this document is to precise the general and particular conditions for the acceptance on a ground disposal site of a low- and middle-level radioactive waste package conditioned in a durable confining shell. This specification concerns the wastes that contain beta and gamma decay radionuclides and/or long life alpha decay radionuclides in higher quantities than accepted for the protective coatings. Physico-chemical and mechanical specifications are given for the wastes, the fixing material, the confining shell and the container. Accepted limits for degassing and dose rates, surface contamination, dimensions and weight are given. The agreement is delivered by the ANDRA after the package has satisfied the different mechanical, chemical, fire, moisture and radiation resistance tests. (J.S.). 1 fig., 3 tabs., 1 glossary

  13. Near-Field Acoustic Power Level Analysis of F31/A31 Open Rotor Model at Simulated Cruise Conditions, Technical Report II

    Science.gov (United States)

    Sree, Dave

    2015-01-01

    Near-field acoustic power level analysis of F31A31 open rotor model has been performed to determine its noise characteristics at simulated cruise flight conditions. The non-proprietary parts of the test data obtained from experiments in the 8x6 supersonic wind tunnel were provided by NASA-Glenn Research Center. The tone and broadband components of total noise have been separated from raw test data by using a new data analysis tool. Results in terms of sound pressure levels, acoustic power levels, and their variations with rotor speed, freestream Mach number, and input shaft power, with different blade-pitch setting angles at simulated cruise flight conditions, are presented and discussed. Empirical equations relating models acoustic power level and input shaft power have been developed. The near-field acoustic efficiency of the model at simulated cruise conditions is also determined. It is hoped that the results presented in this work will serve as a database for comparison and improvement of other open rotor blade designs and also for validating open rotor noise prediction codes.

  14. Analysis of Technical State of Thermal and Mechanical Equipment of Thermal Power Stations in the Republic of Belarus under Conditions of Investment Deficit

    Directory of Open Access Journals (Sweden)

    S. N. Shichko

    2004-01-01

    Full Text Available The paper contains an analysis of the equipment state at a number of thermal power stations. This analysis is made on the basis of indifferent curves. Relationship of two factors is taken as a criterion for estimation of the equipment state. These factors are faultiness (parameter of failure fi"equency and operating time from the moment when the equipment was put into operation. It is noted that operation of the equipment in excess of specified life without replacement of so-called «weab> elements and estimation of metal state will lead to conditions of high risk in opieration of such equipment.

  15. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    Overview From a technical perspective, CMS has been in “beam operation” state since 6th November. The detector is fully closed with all components operational and the magnetic field is normally at the nominal 3.8T. The UXC cavern is normally closed with the radiation veto set. Access to UXC is now only possible during downtimes of LHC. Such accesses must be carefully planned, documented and carried out in agreement with CMS Technical Coordination, Experimental Area Management, LHC programme coordination and the CCC. Material flow in and out of UXC is now strictly controlled. Access to USC remains possible at any time, although, for safety reasons, it is necessary to register with the shift crew in the control room before going down.It is obligatory for all material leaving UXC to pass through the underground buffer zone for RP scanning, database entry and appropriate labeling for traceability. Technical coordination (notably Stephane Bally and Christoph Schaefer), the shift crew and run ...

  16. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

    In this report we will review the main achievements of the Technical Stop and the progress of several centrally-managed projects to support CMS operation and maintenance and prepare the way for upgrades. Overview of the extended Technical Stop  The principal objectives of the extended Technical Stop affecting the detector itself were the installation of the TOTEM T1 telescopes on both ends, the readjustment of the alignment link-disk in YE-2, the replacement of the light-guide sleeves for all PMs of both HFs, and some repairs on TOTEM T2 and CASTOR. The most significant tasks were, however, concentrated on the supporting infrastructure. A detailed line-by-line leak search was performed in the C6F14 cooling system of the Tracker, followed by the installation of variable-frequency drives on the pump motors of the SS1 and SS2 tracker cooling plants to reduce pressure transients during start-up. In the electrical system, larger harmonic filters were installed in ...

  17. Partitioning and transmutation of transuranium elements under nuclear phase-out conditions. Technically reliable?; Transmutation von Transuranen unter den Randbedingungen des Kernenergieausstiegs. Technisch machbar?

    Energy Technology Data Exchange (ETDEWEB)

    Merk, Bruno; Rohde, Ulrich [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany)

    2016-04-15

    The German government has decided for the nuclear phase out, but a decision on a strategy for the management of the highly radioactive waste is not defined yet. Partitioning and Transmutation (P and T) could be considered as a technological option in the process of management of highly radioactive waste management, therefore a wide study has been conducted. In this group objectives for P and T and the boundary conditions of the phase out have been discussed. The fulfillment of the given objectives is analyzed using simulations of molten salt reactors with fast neutron spectrum. It is shown that the efficient transmutation of all existing transuranium isotopes would be possible in 3 to 4 reactors in a time frame of 45 to 60 years. Further on a detailed balance of different isotopic inventories is given to allow a deeper understanding of the processes during transmutation.

  18. Assisted delivery with forceps

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000509.htm Assisted delivery with forceps To use the sharing features on ... called vacuum assisted delivery . When is a Forceps Delivery Needed? Even after your cervix is fully dilated ( ...

  19. Corrosion of carbon steel under anaerobic conditions in a repository for SF and HLW in Opalinus Clay. Technical report 08-12

    International Nuclear Information System (INIS)

    King, F.

    2008-10-01

    Nagra is considering carbon steel as one of the canister material options for the disposal of high level waste and spent fuel in a deep geological repository in Opalinus Clay. Following a brief period of aerobic conditions, the canister will be exposed to an anaerobic environment for much of its service life. Knowledge of the rate of anaerobic corrosion is important not only for estimating the canister lifetime but also for determining the rate of hydrogen generation. This report describes a critical review of the anaerobic corrosion behaviour of carbon steel under environmental conditions similar to those expected in the repository. The aims of the report are: 1. to recommend a (range of) long-term anaerobic corrosion rate(s) for carbon steel canisters, and 2. to justify the use of this rate in safety assessments based on a mechanistic understanding of the structure and properties of the protective corrosion product films. The review is based on selected studies from various national nuclear waste management programs, supplemented where appropriate with studies from other applications and with evidence from archaeological analogues. The corrosion rate of carbon steel decreases with time because of the formation of a protective surface film. There are differences in behaviour in bulk solution and in the presence of compacted bentonite. In bulk solution, the corrosion rate decreases to an apparent steady-state rate after a period of approximately six months, with a long-term rate of the order of 0.1 μm·.yr -1 . The surface film comprises a duplex structure, with a magnetite outer layer and a spinel-type inner layer. In compacted clay systems the rate of decrease in corrosion rate is slower, with steady state not being reached after several years of exposure. There is a significant body of evidence from apparently well-conducted experiments that indicate an anaerobic corrosion rate of the order of 1-2 μm·yr -1 in systems containing compacted clay and the

  20. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - GIS analysis Franches Montagnes, Switzerland - Documentation of GIS concepts, methods and results

    Energy Technology Data Exchange (ETDEWEB)

    Daellenbach, F.; Schaffner, B. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents part of the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report documents the use of the Geographic Information Systems (GIS) methodology for the 'Franches Montagnes' Region in Switzerland, whereby the most significant of the model's layers was found to be the wind velocity layer.

  1. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digital relief analysis - Abstract of work package 7

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents an abstract of the development work carried out by the Swiss meteorology specialists METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report presents an abstract of the work done as part of the Work Package 7 of the Alpine Windharvest project.

  2. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Alpine Space wind map - Modeling approach

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Remund, J. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents describes the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report discusses two modelling approaches investigated for use in the definition of a wind map for the alpine area. The method chosen and its application are discussed. The various sources of information for input to the model are listed and discussed.

  3. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - CFD modelling evaluation - Summary of WindSim CFD modelling procedure and validation

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The report describes the development of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. The report deals with the use of computational fluid dynamics and wind simulation modelling techniques and their validation. Recommendations on the use of the results are made.

  4. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - GIS analysis methodology - Workbook and results

    Energy Technology Data Exchange (ETDEWEB)

    Daellenbach, F.; Schaffner, B. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The report describes the development of basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. The report deals with the use of Geographic Information Systems (GIS) methodology, which includes three steps: the identification of limiting factors for wind power production, the compilation of a GIS layer for each of these factors and, thirdly, their aggregation into a result layer. The methodology was implemented for four case studies in Austria, Italy, Slovenia and Switzerland.

  5. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Switzerland (please sp...

  6. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Swi...

  7. 46 CFR 160.066-13 - Technical tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Technical tests. 160.066-13 Section 160.066-13 Shipping....066-13 Technical tests. (a) The following conditions apply to technical tests as described in this... signals are protected by sealed packaging, then the conditioning for the technical tests must be conducted...

  8. Assessment of Extension Service Delivery on Improved Cassava ...

    African Journals Online (AJOL)

    Extension service delivery is too often merely seen as a vehicle for spreading scientific and technical progress and technology transfer. In the real sense, however, dissemination of knowledge is not a one way affair from scientists to producers. The study was conducted to assess extension service delivery on improved ...

  9. INDOT Technical Training Plan : [Technical Summary

    Science.gov (United States)

    2012-01-01

    A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

  10. Technical specifications for the Bulk Shielding Reactor

    International Nuclear Information System (INIS)

    1982-04-01

    Technical specifications are presented concerning the safety limits and limiting safety system settings; limiting conditions for operation; surveillance requirements; design features; and administrative controls

  11. The Effect of Different Delivery Conditions on the Accelerated Degradation of Structural Steel in the Coal Mine Environment / Wpływ Różnego Stanu Dostawy Na Przyspieszoną Degradację Stali Konstrukcyjnej W Środowisku Kopalnianym

    Science.gov (United States)

    Pawłowski, Bogdan; Bała, Piotr

    2012-12-01

    The main objective of this work was to determine the effect of different delivery conditions on the accelerated degradation of structural steels used for lifting beams (rails) of the monorail transport systems. Some of these rails, made of the same steel grade as others, undergoes accelerated corrosion in the coal mine environment. Corrosion degradation occurs much faster (more than two times faster), comparing to the same steel grade rails operated under the same conditions but with different microstructures. However, all the provided rails meet the requirements of appropriate standards for steel on the lifting beams of the monorail transport systems. The investigations were carried out on rails made of the same steel grade but with different microstructures and showed that the main factor influencing the accelerated corrosion degradation of tested steels is the delivery condition, so-called "as rolled" condition. The greatest resistance to the accelerated corrosion showed rails in the normalized or normalizing rolling condition.

  12. SMART POLYMERS: INNOVATIONS IN NOVEL DRUG DELIVERY

    OpenAIRE

    Apoorva Mahajan; Geeta Aggarwal

    2011-01-01

    Smart polymers are attracting the researchers for development of novel drug delivery systems. Importance of smart polymers is rising day by day as these polymers undergo large reversible, physical or chemical changes in response to small changes in the environmental conditions such as pH, temperature, dual- stimuli, light and phase transition. Smart polymers are representing promising means for targeted drug delivery, enhanced drug delivery, gene therapy, actuator stimuli and protein folders....

  13. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digital relief analysis - Abstract of work package 7; Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digitale Relief-Analyse - Zusammenfassung von Arbeitspaket 7

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report describes the development work carried out by the Swiss meteorology specialists METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report presents a summary of work done on the digital relief analysis used in various stages of the project, its validation and use.

  14. TECHNICAL COORDINATION

    CERN Document Server

    A. Ball and W. Zeuner

    2013-01-01

    For the reporting period, the CMS common systems and infrastructure worked well, without failures that caused significant data losses. One more disconnection of the magnet cold box occurred in the shadow of interruptions in data taking, caused by a series of technical faults. The recognition during 2012 that re-connection can only safely be done at around 2 T implies a minimum magnet recovery time of 12 hours and raises serious concerns about the number of ramping cycles of the magnet these incidents cause. This has triggered studies of how to make the cryo-system of the magnet more robust against failures. The proton-proton run ended just before the end-of-year CERN closure, during which CASTOR was installed on the negative end of CMS and both ZDC calorimeters were installed in TAN absorbers the LHC tunnel, in preparation for the heavy-ion run. The installation of CASTOR was an excellent “engineering test” of procedures for working in an activated environment. Despite some technical pr...

  15. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    Summary of progress since last CMS week. Ten years of construction work have been completed. CMS is closed, in very close to the ideal low luminosity configuration, and performed well in the first tests with LHC beam. Behind this encouraging news is the story of a summer of intense commitment by many teams (from the collaboration and 3 CERN departments) working together, against the clock and despite many minor setbacks, to ensure that the experiment was ready to play a leading role in the excitement of September 10. Following beampipe bakeout and refill with pure neon, a magnificent effort by the ECAL group and the pt 5 technical crew made it possible to install and commission all 4 ECAL endcap Dees before the end of August. In the shadow of this activity, the barrel and forward pixel trackers and part of the beam monitoring were installed within the vac tank. The pt 5 technical teams then succeeded in safely removing the 20t installation tables and their support blocks from beneath the already installed ...

  16. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

      Operational experience 2011 CMS is approaching the end of a very successful year of operation. Proton- proton running ended in the late afternoon of 30th October with a stunning 5.73 fb–1 delivered by LHC, of which CMS recorded 5.22 fb–1. During heavy-ion operation, which continues until 7th December, both the accelerator and the CMS detector have also performed very well. Despite the encouraging overall reliability of technical operation, several infrastructure failures which occurred since the last Bulletin are worthy of mention, with one leading for the first time to significant data-loss. On 10th July, a CERN-wide power failure brought down essentially all services including the magnet, due to an MCS setting being left in “manual” after the recent technical stop, but there was no significant damage and the detector was operational before the LHC, despite a slow and tortuous recovery (one of several indications this year that there is room for improve...

  17. Seminar series on `Technical building installations`. The example of refrigeration technology for air conditioning plants. Practice-oriented advanced training at Technische Akademie Esslingen training centre. Seminar series on `Technical building installations`; Lehrgangsreihe ``Technische Gebaeudeausruestung``. Beispiel: Kaeltetechnik in Klimaanlagen. Praxisnahe Fortbildung am Weiterbildungszentrum Technische Akademie Esslingen. Lehrgangsreihe ``Technische Gebaeudeausruestung``

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-04-01

    The advanced training on ``Technical Building Installations`` at the Technische Akademie Esslingen has been held regularly over a period of 18 years now. The training lasts several days and comprises a total of 12 courses on the subjects: ventilation and air-conditioning, stages A-D; refrigeration, stage A; refrigeration in air conditioning glants; energy concepts for buildings and industry, stages A and B; heating in old and new buildings; sanitation, stages A and B; and, sanitation in old and new buildings. In the present article the structure of the training is illustrated for the example of refrigeration in air conditioning plants. The article also discusses questions concerning the assessment of the training and its benefit to the participants. (BWI) [Deutsch] Seit nunmehr 18 Jahren wird an der Technischen Akademie Esslingen TAE die mehrtaegige Fortbildungsveranstaltung ``Technische Gebaeudeausruestung`` durchgefuehrt. Insgesamt werden in diesem gesamten Themenkomplex 12 Lehrgaenge angeboten: Raumlufttechnik, Teil A-D; Kaeltetechnik Teil A - Kaeltetechnik in Klimaanlagen, Energiekonzepte fuer Gebaeude und Industrie, Teil A und B, Heiztechnik in Neu- und Altbauten, Sanitaertechnik Teil A und B. Am Beispiel des Themenbereiches Kaeltetechnik in Klimaanlagen wird die Lehrgangsausrichtung dargestellt. Ferner werden Fragen der Lehrgangsbewertung und der Nutzen fuer die Teilnehmer diskutiert. (BWI)

  18. Technical presentation

    CERN Multimedia

    GS Department

    2010-01-01

    10 March 2010 DYNEOS 10:00 – 12:00 - Main Building, Room B, 61-1-009 Dyneos AG is active in the fields of photonics, laser and high-precision positioning. Our highly qualified engineer team has more than 30 years of experience in electro-optical solutions sales. The engineers are supported by a technical and administrative team. We are focused on the Swiss market and represent six suppliers (Coherent, PI Physik Instrumente, SIOS, Nanonics Imaging, APE, Ekspla) in order to give a qualified sales and service support to our customers. Our products are dedicated to the research field as well as to industry. In addition to standard catalog products, we offer custom designs to fulfill the specific needs of OEM customers or specific applications.

  19. Technical presentation

    CERN Document Server

    FP Department

    2009-01-01

    07 April 2009 Technical presentation by Leuze Electronics: 14.00 – 15.00, Main Building, Room 61-1-017 (Room A) Photoelectric sensors, data identification and transmission systems, image processing systems. We at Leuze Electronics are "the sensor people": we have been specialising in optoelectronic sensors and safety technology for accident prevention for over 40 years. Our dedicated staff are all highly customer oriented. Customers of Leuze Electronics can always rely on one thing – on us! •\tFounded in 1963 •\t740 employees •\t115 MEUR turnover •\t20 subsidiaries •\t3 production facilities in southern Germany Product groups: •\tPhotoelectric sensors •\tIdentification and measurements •\tSafety devices

  20. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2010-01-01

    Overview Once again, the bulk of this article reviews the intense activity of a recently completed shutdown, which, although quite unforeseeable until a few weeks before it started, proved by its success that our often advertised capability to conduct major maintenance within a two month period is real. Although safely completed, on-time to remarkable precision, the activity was not without incident, and highlighted our dependence on many experienced, specialist teams and their precise choreography. Even after the yoke was safely closed, magnet re-commissioning and beampipe pumpdown showed new and thought-provoking behaviour. The struggle to maintain adequate technical resources will be a pre-occupation over the coming months, in parallel with the start of truly sustained operation, for which various procedures are still being put in place. Planning for future shutdowns must now become a high priority, with many working groups and task forces already in existence to prepare infrastructure improvements and to...

  1. Technical presentation

    CERN Document Server

    FI Department

    2008-01-01

    RADIOSPARES, the leading catalogue distributor of components (electronic, electrical, automation, etc.) and industrial supplies will be at CERN on Friday 3 October 2008 (Main Building, Room B, from 9.00 a.m. to 3.00 p.m.) to introduce its new 2008/2009 catalogue. This will be the opportunity for us to present our complete range of products in more detail: 400 000 part numbers available on our web site (Radiospares France, RS International, extended range of components from other manufacturers); our new services: quotations, search for products not included in the catalogue, SBP products (Small Batch Production: packaging in quantities adapted to customers’ requirements); partnership with our focus manufacturers; demonstration of the on-line purchasing tool implemented on our web site in conjunction with CERN. RADIOSPARES will be accompanied by representatives of FLUKE and TYCO ELECTRONICS, who will make presentations, demonstrate materials and answer any technical questio...

  2. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Tuesday 3 February 2004 From 09:00 to 13:30 - Training Centre Auditorium - bldg. 593, room 11 USB (Universal Serial Bus) CYPRESS Seminar Claudia Colombini, Field Application Engineer CYPRESS ActiveComp Electronic GmbH D-85077 MANCHING, Germany As a pioneer in USB, CYPRESS sets the standard for cost-effective solutions without sacrificing functionality, performance or reliability. Having shipped over 200 million USB devices, Cypress is the undisputed market leader and demonstrates unmatched USB expertise. With the industry's broadest selection of USB solutions, Cypress has the right silicon, software and support for every USB application, from Low-speed to High-Speed and USB On-The-Go (OTG). 9:00 - 10:30 Overview of USB systems. USB CYPRESS product overview. Peripherals: Low Speed, Full Speed, High Speed (1.1 and 2.0). Hub Solutions, Embedded Host Solutions, On-The-Go (OTG) and wireless USB. USB Development Tools (first part) 10:30 -...

  3. Transdermal drug delivery

    OpenAIRE

    Prausnitz, Mark R.; Langer, Robert

    2008-01-01

    Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs. Second-generation delivery systems using chemical enhancers, non-cavitational ultrasound and iontophoresis have also resulted in clinical products; the ability ...

  4. Efficiency and economics of hydrogen delivery

    International Nuclear Information System (INIS)

    Liu, Y.; Bharadwaj, R.; Balan, C.; Garces, L.; Smith, D.

    2003-01-01

    The viability and penetration of fuel cell based electricity production will be mainly determined by the efficient, cost effective production and delivery of hydrogen. This study focuses on the transportation efficiency and cost of hydrogen delivery for both centrally produced hydrogen as well as electricity scenarios. The efficiency and economics of energy delivery depend on the quantity of energy to be transported and transportation distance. Energy delivery models were developed for Hydrogen delivery as compressed gas or cryogenic liquid using truck or pipeline. For comparison, models were also developed for high voltage AC electricity transmission. Major parameters that influence the performance of the energy transmission systems under normal operating conditions were modeled. The models use energy transported and delivery distance as independent variables. The results were validated against similar reports, government surveys and other publications. Energy delivery efficiency and costs were used to compare and evaluate the different delivery options. Effect of uncertainty and sensitivity of parameters on modeling results were also studied. The systems were compared on an equivalent basis. The analysis also identifies the trade-offs for electricity transmission and electrolysis application at the point of use for Hydrogen delivery. These results provide a consistent framework for evaluation of delivery options on energy efficiency basis. (author)

  5. Transdermal drug delivery

    Science.gov (United States)

    Prausnitz, Mark R.; Langer, Robert

    2009-01-01

    Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs. Second-generation delivery systems using chemical enhancers, non-cavitational ultrasound and iontophoresis have also resulted in clinical products; the ability of iontophoresis to control delivery rates in real time provides added functionality. Third-generation delivery systems target their effects to skin’s barrier layer of stratum corneum using microneedles, thermal ablation, microdermabrasion, electroporation and cavitational ultrasound. Microneedles and thermal ablation are currently progressing through clinical trials for delivery of macromolecules and vaccines, such as insulin, parathyroid hormone and influenza vaccine. Using these novel second- and third-generation enhancement strategies, transdermal delivery is poised to significantly increase impact on medicine. PMID:18997767

  6. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    2013-01-01

      Since the last report, much visible progress has been made, as the LS1 programme approaches the halfway point. From early October, technical and safety shift-crew have been present around the clock, allowing detectors to stay switched on overnight, ensuring that safety systems are operational and instructions for non-expert shift-crew are clear. LS1 progress Throughout the summer, whilst the solenoid vacuum tank and YB0 surfaces were accessible, an extensive installation programme took place to prepare for Tracker colder operation and the PLT installation, in 2014, the Phase 1 Pixel Tracker installation, in 2016–’17, and the HCAL Phase 1 upgrade completion, ending in LS2. This included pipework for N2 or dry air to flush the Tracker bulkhead region, many sensors to monitor temperature and dew point in the Tracker and its service channels, heating wires outside the Tracker cooling bundles, supports for the new vacuum-jacketed, concentric, CO2 Pixel cooling lines, the PLT cool...

  7. How to achieve optimal organization of primary care service delivery at system level: lessons from Europe.

    Science.gov (United States)

    Pelone, Ferruccio; Kringos, Dionne S; Spreeuwenberg, Peter; De Belvis, Antonio G; Groenewegen, Peter P

    2013-09-01

    To measure the relative efficiency of primary care (PC) in turning their structures into services delivery and turning their services delivery into quality outcomes. Cross-sectional study based on the dataset of the Primary Healthcare Activity Monitor for Europe project. Two Data Envelopment models were run to compare the relative technical efficiency. A sensitivity analysis of the resulting efficiency scores was performed. PC systems in 22 European countries in 2009/2010. Model 1 included data on PC governance, workforce development and economic conditions as inputs and access, coordination, continuity and comprehensiveness of care as outputs. Model 2 included the previous process dimensions as inputs and quality indicators as outputs. There is relatively reasonable efficiency in all countries at delivering as many as possible PC processes at a given level of PC structure. It is particularly important to invest in economic conditions to achieve an efficient structure-process balance. Only five countries have fully efficient PC systems in turning their services delivery into high quality outcomes, using a similar combination of access, continuity and comprehensiveness, although they differ on the adoption of coordination of services. There is a large variation in efficiency levels obtained by countries with inefficient PC in turning their services delivery into quality outcomes. Maximizing the individual functions of PC without taking into account the coherence within the health-care system is not sufficient from a policymaker's point of view when aiming to achieve efficiency.

  8. 7 CFR 46.44 - Good delivery.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF PERISHABLE AGRICULTURAL COMMODITIES REGULATIONS (OTHER... conditions, will meet the following additional requirements on delivery at the contract destination: (a...

  9. Technical note:

    Indian Academy of Sciences (India)

    WIN uE10

    de Ciencias, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena, ... this key species of high-Andean ecosystems, and assist restoration and conservation ... environmental conditions (3500-4200 m) in the high-Andean Río Estrecho ...

  10. VGB-requirements regarding technical data for power plants

    International Nuclear Information System (INIS)

    Richnow, Joerg

    2009-01-01

    Much of the technical plant data resulting from the planning, construction and start-up of power plants is needed for subsequent management and maintenance. Because of this, VGB has taken the initiative and has defined standard minimum requirements from power plant operators for technical plant data. They relate to the details and structure of this data, the definition of material classes and characteristics for the main power plant components and IT implementation for delivery of the technical plant data. (orig.)

  11. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-03-03

    This document describes the qualitative evaluation of frequency and consequences for DST and SST representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant structures, systems and components (SSCs) and/or technical safety requirements (TSRs) were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support WP-13033, Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  12. eDelivery

    Data.gov (United States)

    US Agency for International Development — eDelivery provides the electronic packaging and delivery of closed and complete OPM investigation files to government agencies, including USAID, in a secure manner....

  13. Vacuum-assisted delivery

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000514.htm Vacuum-assisted delivery To use the sharing features on this page, ... through the birth canal. When is Vacuum-assisted Delivery Needed? Even after your cervix is fully dilated ( ...

  14. Articulating feedstock delivery device

    Science.gov (United States)

    Jordan, Kevin

    2013-11-05

    A fully articulable feedstock delivery device that is designed to operate at pressure and temperature extremes. The device incorporates an articulating ball assembly which allows for more accurate delivery of the feedstock to a target location. The device is suitable for a variety of applications including, but not limited to, delivery of feedstock to a high-pressure reaction chamber or process zone.

  15. UAV Delivery Monitoring System

    Directory of Open Access Journals (Sweden)

    San Khin Thida

    2018-01-01

    Full Text Available UAV-based delivery systems are increasingly being used in the logistics field, particularly to achieve faster last-mile delivery. This study develops a UAV delivery system that manages delivery order assignments, autonomous flight operation, real time control for UAV flights, and delivery status tracking. To manage the delivery item assignments, we apply the concurrent scheduler approach with a genetic algorithm. The present paper describes real time flight data based on a micro air vehicle communication protocol (MAVLink. It also presents the detailed hardware components used for the field tests. Finally, we provide UAV component analysis to choose the suitable components for delivery in terms of battery capacity, flight time, payload weight and motor thrust ratio.

  16. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    Introduction Underground installation of the initial CMS detector is almost complete. During this CMS week the detector will reach the minimum necessary condition allowing closure for beam. Configuration for pixel, BCM and endcap ECAL installation will then follow, with the installation of one or both endcap ECAL beingdependent on the actual date when beams may be expected through point 5. As we approach the culmination of 9 years of assembly at Cessy, it is appropriate to pay tribute once again to the continuing dedication and flexibility of all the CERN, collaboration and contractor teams working at point 5, including recently our colleagues from AT/VAC. There is every indication that the legacy of their hard work will be a superb scientific instrument. Safety The final burst of assembly activity in the UXC before closing for beam will involve the familiar worksite risks of heavy manipulation, restricted workspaces, multiple activity and work at height, now amplified by the presence of the very fragile be...

  17. Artificial changes of weather conditions

    International Nuclear Information System (INIS)

    Kozin, I.D.; Vasil'ev, I.V.; Fedulina, I.N.; Zakizhan, Z.Z.; Khalimov, R.A.

    2005-01-01

    Unfavorable weather conditions have undesirable ecological consequences, causes remarkable economical damage. In the paper authors consider physical factors and technical methods of influence on cloud formation. (author)

  18. NWMO transportation technical work program

    International Nuclear Information System (INIS)

    Hatton, C.

    2015-01-01

    This paper describes technical work program for the transportation nuclear waste by the Nuclear Waste Management Organization (NWMO). Transportation work program involves risk assessment which under normal conditions involves dose assessment to the worker and the public as well as consideration of transportation system routing and operations. It also involves possible accident scenarios using forensic modelling and probability analysis.

  19. NWMO transportation technical work program

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, C. [Nuclear Waste Management Organization, Toronto, ON (Canada)

    2015-07-01

    This paper describes technical work program for the transportation nuclear waste by the Nuclear Waste Management Organization (NWMO). Transportation work program involves risk assessment which under normal conditions involves dose assessment to the worker and the public as well as consideration of transportation system routing and operations. It also involves possible accident scenarios using forensic modelling and probability analysis.

  20. Mathematical modeling of a process the rolling delivery

    Science.gov (United States)

    Stepanov, Mikhail A.; Korolev, Andrey A.

    2018-03-01

    An adduced analysis of the scientific researches in a domain of the rolling equipments, also research of properties the working material. A one of perspective direction of scientific research this is mathematical modeling. That is broadly used in many scientific disciplines and especially at the technical, applied sciences. With the aid of mathematical modeling it can be study of physical properties of the researching objects and systems. A research of the rolling delivery and transporting devices realized with the aid of a construction of mathematical model of appropriate process. To be described the basic principles and conditions of a construction of mathematical models of the real objects. For example to be consider a construction of mathematical model the rolling delivery device. For a construction that is model used system of the equations, which consist of: Lagrange’s equation of a motion, describing of the law conservation of energy of a mechanical system, and the Navier - Stokes equations, which characterize of the flow of a continuous non-compressed fluid. A construction of mathematical model the rolling deliver to let determined of a total energy of device, and therefore to got the dependence upon the power of drive to a gap between of rolls. A corroborate the hypothesis about laminar the flow of a material into the rolling gap of deliver.

  1. Technical management of difference in CEPR nuclear power project

    International Nuclear Information System (INIS)

    Guo Ruiting

    2014-01-01

    The Thesis dissertate the application of technical management of difference in CEPR Nuclear Power Project from EPR technical bases, condition of a nuclear power plant site, engineering and procurement, construction, quality management, schedule management and experience feedback aspects. (author)

  2. Strategy of technical innovation

    International Nuclear Information System (INIS)

    Lee, Ga Jong

    1990-12-01

    This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

  3. Project delivery system (PDS)

    CERN Document Server

    2001-01-01

    As business environments become increasingly competitive, companies seek more comprehensive solutions to the delivery of their projects. "Project Delivery System: Fourth Edition" describes the process-driven project delivery systems which incorporates the best practices from Total Quality and is aligned with the Project Management Institute and ISO Quality Standards is the means by which projects are consistently and efficiently planned, executed and completed to the satisfaction of clients and customers.

  4. A review of technology and trends in document delivery services

    Energy Technology Data Exchange (ETDEWEB)

    Bourne, C P [DIALOG Information Services, Inc., Palo Alto, CA (United States)

    1990-05-01

    This paper reviews the major lines of technical development being pursued to extend or replace traditional inter-library loan and photocopy service and to facilitate the delivery of source documents to individual end users. Examples of technical approaches discussed are: (1) the inclusion of full text and image data in central online systems; (2) image workstations such as the ADONIS and UMI systems; and (3) the use of electronic networks for document ordering and delivery. Some consideration is given to the policy implications for libraries and information systems. (author). 11 tabs.

  5. A review of technology and trends in document delivery services

    International Nuclear Information System (INIS)

    Bourne, C.P.

    1990-05-01

    This paper reviews the major lines of technical development being pursued to extend or replace traditional inter-library loan and photocopy service and to facilitate the delivery of source documents to individual end users. Examples of technical approaches discussed are: 1) the inclusion of full text and image data in central online systems; 2) image workstations such as the ADONIS and UMI systems; and 3) the use of electronic networks for document ordering and delivery. Some consideration is given to the policy implications for libraries and information systems. (author). 11 tabs

  6. Protein-Based Drug-Delivery Materials

    OpenAIRE

    Jao, Dave; Xue, Ye; Medina, Jethro; Hu, Xiao

    2017-01-01

    There is a pressing need for long-term, controlled drug release for sustained treatment of chronic or persistent medical conditions and diseases. Guided drug delivery is difficult because therapeutic compounds need to survive numerous transport barriers and binding targets throughout the body. Nanoscale protein-based polymers are increasingly used for drug and vaccine delivery to cross these biological barriers and through blood circulation to their molecular site of action. Protein-based pol...

  7. Trojan technical specification verification project

    International Nuclear Information System (INIS)

    Bates, L.; Rickenback, M.

    1991-01-01

    The Trojan Technical Specification Verification (TTSV) project at the Trojan plant of Portland General Electric Company was motivated by the recognition that many numbers in the Trojan technical specifications (TTS) potentially lacked the consideration of instrument- and/or process-related errors. The plant setpoints were known to consider such errors, but many of the values associated with the limiting conditions for operation (LCO) did not. In addition, the existing plant instrument error analyses were based on industry values that do not reflect the Trojan plant-specific experience. The purpose of this project is to ensure that the Trojan plant setpoint and LCO values include plant-specific instrument error

  8. Technology-mediated therapy for chronic pain management: the challenges of adapting behavior change interventions for delivery with pervasive communication technology.

    Science.gov (United States)

    Rosser, Benjamin A; McCullagh, Paul; Davies, Richard; Mountain, Gail A; McCracken, Lance; Eccleston, Christopher

    2011-04-01

    Adapting therapeutic practice from traditional face-to-face exchange to remote technology-based delivery presents challenges for the therapist, patient, and technical writer. This article documents the process of therapy adaptation and the resultant specification for the SMART2 project-a technology-based self-management system for assisting long-term health conditions, including chronic pain. Focus group discussions with healthcare professionals and patients were conducted to inform selection of therapeutic objectives and appropriate technology. Pertinent challenges are identified, relating to (1) reduction and definition of therapeutic objectives, and (2) how to approach adaptation of therapy to a form suited to technology delivery. The requirement of the system to provide dynamic and intelligent responses to patient experience and behavior is also emphasized. Solutions to these challenges are described in the context of the SMART2 technology-based intervention. More explicit discussion and documentation of therapy adaptation to technology-based delivery within the literature is encouraged.

  9. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-02-18

    This document describes the qualitative evaluation of frequency and consequences for double shell tank (DST) and single shell tank (SST) representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant SSCs and/or TSRS were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support of the Tank Farms Documented Safety Analysis (DSA) and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  10. 48 CFR 52.211-9 - Desired and Required Time of Delivery.

    Science.gov (United States)

    2010-10-01

    ... and rejected. (End of clause) Alternate I (APR 1984). If the delivery schedule is expressed in terms... the ordinary mails. Alternate II (APR 1984). If the delivery schedule is expressed in terms of... that propose delivery of a quantity under such terms or conditions that delivery will not clearly fall...

  11. High Flux Isotope Reactor technical specifications

    International Nuclear Information System (INIS)

    1985-11-01

    This report gives technical specifications for the High Flux Isotope Reactor (HFIR) on the following: safety limits and limiting safety system settings; limiting conditions for operation; surveillance requirements; design features; and administrative controls

  12. Technical specifications for the bulk shielding reactor

    International Nuclear Information System (INIS)

    1986-05-01

    This report provides information concerning the technical specifications for the Bulk Shielding Reactor. Areas covered include: safety limits and limiting safety settings; limiting conditions for operation; surveillance requirements; design features; administrative controls; and monitoring of airborne effluents. 10 refs

  13. Technical specifications for the pool critical assembly

    International Nuclear Information System (INIS)

    1978-07-01

    Technical specifications for the ORNL-PCA Reactor are presented concerning safety limits and limiting safety system settings, limiting conditions for operation, surveillance requirements, design features, and administrative controls

  14. 6. Home deliveries

    African Journals Online (AJOL)

    Sitwala

    determine factors associated with home deliveries. Main outcome ... deliver at home than a health facility compared to those who .... regression analysis, women who had four years of schooling or .... by report bias, the burden of home deliveries is a real challenge .... Journal of Econometrics 1987; 36: 185-204. 14. Michelo ...

  15. Global Delivery Models

    DEFF Research Database (Denmark)

    Manning, Stephan; Larsen, Marcus M.; Bharati, Pratyush

    2013-01-01

    This article examines antecedents and performance implications of global delivery models (GDMs) in global business services. GDMs require geographically distributed operations to exploit both proximity to clients and time-zone spread for efficient service delivery. We propose and empirically show...

  16. Health care delivery systems.

    NARCIS (Netherlands)

    Stevens, F.; Zee, J. van der

    2007-01-01

    A health care delivery system is the organized response of a society to the health problems of its inhabitants. Societies choose from alternative health care delivery models and, in doing so, they organize and set goals and priorities in such a way that the actions of different actors are effective,

  17. Global Delivery Models

    DEFF Research Database (Denmark)

    Manning, Stephan; Møller Larsen, Marcus; Bharati, Pratyush

    -zone spread allowing for 24/7 service delivery and access to resources. Based on comprehensive data we show that providers are likely to establish GDM configurations when clients value access to globally distributed talent pools and speed of service delivery, and in particular when services are highly...

  18. Ageing management technical information investigations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-15

    In February 2013, there are 50 units of commercial nuclear power plants (NPPs) in Japan. We enter into a period that 20 units of them are operating for more than 30 years. Currently, regulation imposes utilities to conduct ageing technical evaluations of each unit before operation of 30 years from the commissioning, to develop the long term maintenance management policy for next 10 years and to submit to the regulatory authority the policy with the report on ageing management technical evaluation (AMTE) for each NPP. It is necessary for regulatory side to develop technical information bases incorporating latest technical knowledge as operating experiences in domestic and abroad on ageing of the plants necessary to conduct reviews of AMTE for each unit. Based on these standpoints, technical information bases investigations have been conducted from the viewpoints of material degradation of ageing NPPs. In order to develop scientific regulator judgment bases related to ageing management (AM) and long-term operation (LTO), investigations on latest information on ageing management in domestic and abroad are conducted and a set of documents including technical evaluation review manuals necessary to conduct AMTE are prepared. To utilize the results of the investigations for ageing technical evaluation, database including latest information related to AM and LTO are developed, ran and operated. In addition, investigations related to Fugen nuclear plant, under decommissioning plants, investigations on mechanism of stress corrosion cracking (SCC), thermal ageing and preventive technologies for SCC, detection and diagnosis technology for ageing degradation and condition monitoring technology are performed to validate and confirm effectiveness of the technologies. (author)

  19. Reader-Centered Technical Writing

    Science.gov (United States)

    Narayanan, M.

    2012-12-01

    Technical writing is an essential part of professional communication and in recent years it has shifted from a genre-based approach. Formerly, technical writing primarily focused on generating templates of documents and sometimes it was creating or reproducing traditional forms with minor modifications and updates. Now, technical writing looks at the situations surrounding the need to write. This involves deep thinking about the goals and objectives of the project on hand. Furthermore, one observes that it is very important for any participatory process to have the full support of management. This support needs to be well understood and believed by employees. Professional writing may be very persuasive in some cases. When presented in the appropriate context, technical writing can persuade a company to improve work conditions ensuring employee safety and timely production. However, one must recognize that lot of professional writing still continues to make use of reports and instruction manuals. Normally, technical and professional writing addresses four aspects. Objective: The need for generating a given professionally written technical document and the goals the document is expected to achieve and accomplish. Clientele: The clientele who will utilize the technical document. This may include the people in the organization. This may also include "unintended readers." Customers: The population that may be affected by the content of the technical document generated. This includes the stakeholders who will be influenced. Environment: The background in which the document is created. Also, the nature of the situation that warranted the generation of the document. Swiss Psychologist Jean Piaget's view of Learning focuses on three aspects. The author likes to extend Jean Piaget's ideas to students, who are asked to prepare and submit Reader-Centered Technical Writing reports and exercises. Assimilation: Writers may benefit specifically, by assimilating a new object into

  20. Tank waste remediation system retrieval and disposal mission waste feed delivery plan

    International Nuclear Information System (INIS)

    Potter, R.D.

    1998-01-01

    This document is a plan presenting the objectives, organization, and management and technical approaches for the Waste Feed Delivery (WFD) Program. This WFD Plan focuses on the Tank Waste Remediation System (TWRS) Project's Waste Retrieval and Disposal Mission

  1. Communications data delivery system analysis : public workshop read-ahead document.

    Science.gov (United States)

    2012-04-09

    This document presents an overview of work conducted to date around development and analysis of communications data delivery systems for : supporting transactions in the connected vehicle environment. It presents the results of technical analysis of ...

  2. Technical Assistance Plan (TAP)

    Science.gov (United States)

    A Technical Assistance Plan (TAP) enables community groups to retain the services of an independent technical advisor and to provide resources for a community group to help inform other community members about site decisions.

  3. Technical report writing

    Science.gov (United States)

    Vidoli, Carol A.

    1992-01-01

    This manual covers the fundamentals of organizing, writing, and reviewing NASA technical reports. It was written to improve the writing skills of LeRC technical authors and the overall quality of their reports.

  4. Technical Report Writing Today

    DEFF Research Database (Denmark)

    Riordan, Daniel G.

    2014-01-01

    Section 1: Technical Communication Basics (8 chapters on tech com, audiences, tech com process, tech com style, researching, designing pages, using visual aids, describing). Section 2: Technical Communication Applications (7 chapters on sets of instructions, informal reports and email, developing...

  5. Technical training: places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  6. Technical training - places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  7. Technical training: places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tél : 74924)  

  8. VANDAL technical overview

    International Nuclear Information System (INIS)

    Unsworth, M.D.

    1989-07-01

    This document is concerned with the technicalities of the VANDAL code and covers the technical details of each of the systems modules in turn. Covered are SAMPLING, FLOW, VAULT, GEOSPHERE, BIOSPHERE and TIMESTEPPING. (author)

  9. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  10. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Marie Lahchimi, Technical Training Administration (Tel: 74924)

  11. Handbook of Technical Communication

    OpenAIRE

    Mehler , Alexander; Romary , Laurent; Gibbon , Dafydd

    2012-01-01

    International audience; The handbook "Technical Communication" brings together a variety of topics which range from the role of technical media in human communication to the linguistic, multimodal enhancement of present-day technologies. It covers the area of computer-mediated text, voice and multimedia communication as well as of technical documentation. In doing so, the handbook takes professional and private communication into account. Special emphasis is put on technical communication bas...

  12. What Is a Cesarean Delivery?

    Science.gov (United States)

    ... Twitter Pinterest Email Print What is a cesarean delivery? A cesarean delivery is a surgical procedure in which a fetus ... 32.2% of U.S. births were by cesarean delivery. 2 The CDC also found that the number ...

  13. The Apollo experiment for document delivery via satellite communication

    Science.gov (United States)

    1985-03-01

    Dutch participation possibilities in the Apollo document delivery project, wishes and idea's of potential user and tender groups, and plans and activities of Dutch institutes and companies, are surveyed. The Apollo storage and transport system, demand and administration network, potential markets, and subject areas of the documents are investigated. Utilization areas (scientific, technical, administration, and business information) are listed. High tariffs and the lack of necessary provision make a direct participation strategy impossible. However, in the experimental phase, Dutch companies must be allowed to contribute in technical developments and availability of organizational and technical facilities must be stimulated.

  14. Teaching Technical Writing - Towards Technical Writing

    DEFF Research Database (Denmark)

    Kastberg, Peter

    2000-01-01

    In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm that ...... of technical writing.......In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm...... that used to govern what the quality of an LSP text should be as opposed to the standpoint, which I advocate. By way of summing up, I will show how a university curriculum is designed so that - upon graduation - the technical translator could also be methodological quite well suited to take on the challenge...

  15. MINI-SLAR delivery system

    International Nuclear Information System (INIS)

    Alstein, D.

    1996-01-01

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce 'A', Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level 'D' faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs

  16. MINI-SLAR delivery system

    Energy Technology Data Exchange (ETDEWEB)

    Alstein, D [Ontario Hydro, Tiverton, ON (Canada). Bruce Nuclear Generating Station-A; Dalton, K [Spectrum Engineering, Peterborough, ON (Canada)

    1997-12-31

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce `A`, Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level `D` faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs.

  17. TRANSDERMAL DRUG DELIVERY SYSTEM: REVIEW

    OpenAIRE

    Vishvakarama Prabhakar; Agarwal Shivendra; Sharma Ritika; Saurabh Sharma

    2012-01-01

    Various new technologies have been developed for the transdermal delivery of some important drugs. Today about 74% of drugs are taken orally and are found not to be as effective as desired. To improve such characters transdermal drug delivery system was emerged. Drug delivery through the skin to achieve a systemic effect of a drug is commonly known as transdermal drug delivery and differs from traditional topical drug delivery. Transdermal drug delivery systems (TDDS) are dosage forms involve...

  18. Technical rules in law

    Energy Technology Data Exchange (ETDEWEB)

    Debelius, J

    1978-08-01

    An important source of knowledge for technical experts is the state of the art reflected by catalogues of technical rules. Technical rules may also achieve importance in law due to a legal transformation standard. Here, rigid and flexible reference are controversial with regard to their admissibility from the point of view of constitutional law. In case of a divergence from the generally accepted technical rules, it is assumed - refutably - that the necessary care had not been taken. Technical rules are one out of several sources of information; they have no normative effect. This may result in a duty of anyone applying them to review the state of technology himself.

  19. Technical rules in law

    International Nuclear Information System (INIS)

    Debelius, J.

    1978-01-01

    An important source of knowledge for technical experts is the state of the art reflected by catalogues of technical rules. Technical rules may also achieve importance in law due to a legal transformation standard. Here, rigid and flexible reference are controversial with regard to their admissibility from the point of view of constitutional law. In case of a divergence from the generally accepted technical rules, it is assumed - refutably - that the necessary care had not been taken. Technical rules are one out of several sources of information; they have no normative effect. This may result in a duty of anyone applying them to review the state of technology himself. (orig.) [de

  20. Technical specifications for the Oak Ridge Research Reactor

    International Nuclear Information System (INIS)

    1982-03-01

    Technical specifications are presented concerning safety limits and limiting safety system settings; limiting conditions for operation; surveillance requirements; design features; and administrative controls

  1. Technical Evaluation Report

    National Research Council Canada - National Science Library

    Benney, Richard J; Krainski, Walter J

    2006-01-01

    ...) Panel of NATO's Research and Technology Organization (RTO) held a Specialists' Meeting entitled "Fluid Dynamics of Personnel and Equipment Precision Delivery from Military Platforms" in Vilnius, Lithuania...

  2. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Eggeman, Tim [ZeaChem Inc., Lakewood, CO (United States); O' Neill, Brian [ZeaChem Inc., Lakewood, CO (United States)

    2016-08-17

    ZeaChem Inc. and US DOE successfully demonstrated the ZeaChem process for producing sugars and ethanol from high-impact biomass feedstocks. The project was executed over a 5-year period under a $31.25 million cooperative agreement (80:20 Federal:ZeaChem cost share). The project was managed by dividing it into three budget periods. Activities during Budget Period 1 were limited to planning, permitting, and other pre-construction planning. Budget Period 2 activities included engineering, procurement, construction, commissioning, start-up and initial operations through the Independent Engineer Test Runs. The scope of construction was limited to the Chem Frac and Hydrogenolysis units, as the Core Facility was already in place. Construction was complete in December 2012, and the first cellulosic ethanol was produced in February 2013. Additional operational test runs were conducted during Budget Period 3 (completed June 2015) using hybrid poplar, corn stover, and wheat straw feedstocks, resulting in the production of cellulosic ethanol and various other biorefinery intermediates. The research adds to the understanding of the Chem Frac and Hydrogenolysis technologies in that the technical performance of each unit was measured, and the resulting data and operational experience can be used as the basis for engineering designs, thus mitigating risks for deployment in future commercial facilities. The Chem Frac unit was initially designed to be operated as two-stage dilute acid hydrolysis, with first stage conditions selected to remove the hemicellulose fraction of the feedstock, and the second stage conditions selected to remove the cellulose fraction. While the Chem Frac unit met or exceeded the design capacity of 10 ton(dry)/day, the technical effectiveness of the Chem Frac unit was below expectations in its initial two-stage dilute acid configuration. The sugars yields were low, the sugars were dilute, and the sugars had poor fermentability caused by excessive inhibitors

  3. Vaginal delivery - discharge

    Science.gov (United States)

    Pregnancy - discharge after vaginal delivery ... You may have bleeding from your vagina for up to 6 weeks. Early on, you may pass some small clots when you first get up. Bleeding will slowly become ...

  4. Novel ionically crosslinked acrylamide-grafted poly(vinyl alcohol)/sodium alginate/sodium carboxymethyl cellulose pH-sensitive microspheres for delivery of Alzheimer's drug donepezil hydrochloride: Preparation and optimization of release conditions.

    Science.gov (United States)

    Bulut, Emine; Şanlı, Oya

    2016-01-01

    In this work, the graft copolymer, poly(vinyl alcohol)-grafted polyacrylamide (PVA-g-PAAm), was synthesized and characterized by Fourier transform infrared spectroscopy, differential scanning calorimetry, and elemental analysis. Microspheres of PVA-g-PAAm/sodium alginate (NaAlg)/sodium carboxymethyl cellulose (NaCMC) were prepared by the emulsion-crosslinking method and used for the delivery of an Alzheimer's drug, donepezil hydrochloride (DP). The release of DP increased with the increase in drug/polymer ratio (d/p) and PVA-g-PAAm/NaAlg/NaCMC ratio, while it decreased with the increase in the extent of crosslinking. The optimum DP release was obtained as 92.9% for a PVA-g-PAAm/NaAlg/NaCMC ratio of 1/2/1, d/p ratio of 1/8, and FeCl3 concentration of 7% (w/v).

  5. Bribes for Faster Delivery

    OpenAIRE

    Sanyal, Amal

    2000-01-01

    The paper models the practice of charging bribes for faster delivery of essential services in third world countries. It then examines the possibility of curbing corruption by supervision, and secondly, by introducing competition among delivery agents. It is argued that a supervisory solution eludes the problem because no hard evidence of the reduction of corruption can be established for this type of offenses. It is also shown that using more than one supplier cannot eliminate the practice, a...

  6. Geographic delivery models for radiotherapy services

    International Nuclear Information System (INIS)

    Roberts, G.H.; Dunscombe, P.B.; Samant, R.S.

    2002-01-01

    The study described here was undertaken to quantify the societal cost of radiotherapy in idealized urban and rural populations and, hence, to generate a measure of impediment to access. The costs of centralized, distributed comprehensive and satellite radiotherapy delivery formats were examined by decomposing them into institutional, productivity and geographical components. Our results indicate that centralized radiotherapy imposes the greatest financial burden on the patient population in both urban and rural scenarios. The financial burden faced by patients who must travel for radiotherapy can be interpreted as one component of the overall impediment to access. With advances in remote-monitoring systems, it is possible to maintain technical quality while enhancing patient access. However, the maintenance of professional competence will remain a challenge with a distributed service-delivery format. Copyright (2002) Blackwell Science Pty Ltd

  7. A global health delivery framework approach to epilepsy care in resource-limited settings.

    Science.gov (United States)

    Cochran, Maggie F; Berkowitz, Aaron L

    2015-11-15

    The Global Health Delivery (GHD) framework (Farmer, Kim, and Porter, Lancet 2013;382:1060-69) allows for the analysis of health care delivery systems along four axes: a care delivery value chain that incorporates prevention, diagnosis, and treatment of a medical condition; shared delivery infrastructure that integrates care within existing healthcare delivery systems; alignment of care delivery with local context; and generation of economic growth and social development through the health care delivery system. Here, we apply the GHD framework to epilepsy care in rural regions of low- and middle-income countries (LMIC) where there are few or no neurologists. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. TurboTech Technical Evaluation Automated System

    Science.gov (United States)

    Tiffany, Dorothy J.

    2009-01-01

    TurboTech software is a Web-based process that simplifies and semiautomates technical evaluation of NASA proposals for Contracting Officer's Technical Representatives (COTRs). At the time of this reporting, there have been no set standards or systems for training new COTRs in technical evaluations. This new process provides boilerplate text in response to interview style questions. This text is collected into a Microsoft Word document that can then be further edited to conform to specific cases. By providing technical language and a structured format, TurboTech allows the COTRs to concentrate more on the actual evaluation, and less on deciding what language would be most appropriate. Since the actual word choice is one of the more time-consuming parts of a COTRs job, this process should allow for an increase in quantity of proposals evaluated. TurboTech is applicable to composing technical evaluations of contractor proposals, task and delivery orders, change order modifications, requests for proposals, new work modifications, task assignments, as well as any changes to existing contracts.

  9. [Technical efficiency assessment of public primary care providers in the Basque Country (Spain), 2010-2013].

    Science.gov (United States)

    Cordero, José Manuel; Nuño-Solinís, Roberto; Orueta, Juan F; Polo, Cristina; Del Río-Cámara, Mario; Alonso-Morán, Edurne

    2016-01-01

    To evaluate the technical efficiency of primary care units operating in the Basque Health Service during the period 2010-2013, corresponding to the implementation of a care integration strategy by health authorities. This study included 11 of the 12 primary care units in the Basque Health Service during the period 2010-2013. Data envelopment analysis (DEA) was used to assess the technical efficiency of the units. In particular, we applied the extension DEA windows to analyse all units as if they were in a single period (33 observations) as well as a conditional model, which allowed incorporation of the effect of the characteristics of the population covered. The outputs considered were a quality index based on fulfilment of different requirements related to primary care delivery and the rate of avoidable hospitalizations (treated as an undesirable output). The inputs used were the number of physicians, the number of nurses and the costs of prescriptions. The morbidity index was included as an exogenous variable. The results showed that the efficiency of all the units improved during the study period. However, this improvement was not greater in the units incorporated in the integrated healthcare organisation. In a context of global transformation of care delivery in the Basque country in the study period, primary care units increased their efficiency. However, this effect was not larger in vertically integrated primary care providers. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  10. Integrating Information Services in an Academic Setting: The Organizational and Technical Challenge.

    Science.gov (United States)

    Branin, Joseph J.; And Others

    1993-01-01

    Describes a project to integrate the support and delivery of information services to faculty and staff at the University of Minnesota from the planning phase to implementation of a new organizational entity. Topics addressed include technical and organizational integration, control and delivery of services, and networking and organizational fit.…

  11. Writing a technical note.

    Science.gov (United States)

    Ng, K H; Peh, W C G

    2010-02-01

    A technical note is a short article giving a brief description of a specific development, technique or procedure, or it may describe a modification of an existing technique, procedure or device applicable to medicine. The technique, procedure or device described should have practical value and should contribute to clinical diagnosis or management. It could also present a software tool, or an experimental or computational method. Technical notes are variously referred to as technical innovations or technical developments. The main criteria for publication will be the novelty of concepts involved, the validity of the technique and its potential for clinical applications.

  12. Technical Elements (CCT1)

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    2017-01-01

    Many of the aspects dealt with in the CA EPBD are closely interlinked with each other and may refer to both new and existing buildings, as well as to inspection and certification. This is also true for technical aspects, such as the calculation methodologies, and how to include technical systems......’ efficiency or how to integrate renewable energy within them. The central team for Technical Elements deals with issues of a technical nature, which are common to new and existing buildings, and/or with minimum demands, certification and inspection. This report focuses on the implementation of Articles 3, 4...

  13. 48 CFR 212.7003 - Technical data and computer software.

    Science.gov (United States)

    2010-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  14. A Technical/Strategic Paradigm for Online Executive Education

    Science.gov (United States)

    Smith, Marlene A.; Keaveney, Susan M.

    2017-01-01

    This article discusses the development and delivery of online courses for the executive education audience. The goal is to introduce a new framework, the technical/strategic paradigm, that will help educators to identify the pedagogical needs of disparate executive groups and adjust their online course development plans accordingly. We describe…

  15. Microfabrication for Drug Delivery

    Science.gov (United States)

    Koch, Brendan; Rubino, Ilaria; Quan, Fu-Shi; Yoo, Bongyoung; Choi, Hyo-Jick

    2016-01-01

    This review is devoted to discussing the application of microfabrication technologies to target challenges encountered in life processes by the development of drug delivery systems. Recently, microfabrication has been largely applied to solve health and pharmaceutical science issues. In particular, fabrication methods along with compatible materials have been successfully designed to produce multifunctional, highly effective drug delivery systems. Microfabrication offers unique tools that can tackle problems in this field, such as ease of mass production with high quality control and low cost, complexity of architecture design and a broad range of materials. Presented is an overview of silicon- and polymer-based fabrication methods that are key in the production of microfabricated drug delivery systems. Moreover, the efforts focused on studying the biocompatibility of materials used in microfabrication are analyzed. Finally, this review discusses representative ways microfabrication has been employed to develop systems delivering drugs through the transdermal and oral route, and to improve drug eluting implants. Additionally, microfabricated vaccine delivery systems are presented due to the great impact they can have in obtaining a cold chain-free vaccine, with long-term stability. Microfabrication will continue to offer new, alternative solutions for the development of smart, advanced drug delivery systems. PMID:28773770

  16. Advanced SLARette delivery machine

    International Nuclear Information System (INIS)

    Bodner, R.R.

    1995-01-01

    SLARette 1 equipment, comprising of a SLARette Delivery Machine, SLAR Tools, SLAR power supplies and SLAR Inspection Systems was designed, developed and manufactured to service fuel channels of CANDU 6 stations during the regular yearly station outages. The Mark 2 SLARette Delivery Machine uses a Push Tube system to provide the axial and rotary movements of the SLAR Tool. The Push Tubes are operated remotely but must be attached and removed manually. Since this operation is performed at the Reactor face, there is radiation dose involved for the workers. An Advanced SLARette Delivery Machine which incorporates a computer controlled telescoping Ram in the place of the Push Tubes has been recently designed and manufactured. Utilization of the Advanced SLARette Delivery Machine significantly reduces the amount of radiation dose picked up by the workers because the need to have workers at the face of the Reactor during the SLARette operation is greatly reduced. This paper describes the design, development and manufacturing process utilized to produce the Advanced SLARette Delivery Machine and the experience gained during the Gentilly-2 NGS Spring outage. (author)

  17. MRI in ocular drug delivery

    OpenAIRE

    Li, S. Kevin; Lizak, Martin J.; Jeong, Eun-Kee

    2008-01-01

    Conventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug-delivery research. MRI provides a means to non-invasively and continuously monitor ocular drug-delivery systems with a contrast agent or compound labeled with a contrast agent. It is a useful technique in pharmacokinetic studies, evaluation of drug-delivery methods, and drug-delivery de...

  18. Cesarean Delivery for a Life‑threatening Preterm Placental Abruption

    African Journals Online (AJOL)

    Following a failed induction of labor with a deteriorating maternal condition despite resuscitation, emergency cesarean delivery was offered with good maternal outcome. Cesarean delivery could avert further disease progression and possible maternal death in cases of severe preterm placental abruption where vaginal ...

  19. The role of non-technical skills in surgery.

    Science.gov (United States)

    Agha, Riaz A; Fowler, Alexander J; Sevdalis, Nick

    2015-12-01

    Non-technical skills are of increasing importance in surgery and surgical training. A traditional focus on technical skills acquisition and competence is no longer enough for the delivery of a modern, safe surgical practice. This review discusses the importance of non-technical skills and the values that underpin successful modern surgical practice. This narrative review used a number of sources including written and online, there was no specific search strategy of defined databases. Modern surgical practice requires; technical and non-technical skills, evidence-based practice, an emphasis on lifelong learning, monitoring of outcomes and a supportive institutional and health service framework. Finally these requirements need to be combined with a number of personal and professional values including integrity, professionalism and compassionate, patient-centred care.

  20. The role of non-technical skills in surgery

    Science.gov (United States)

    Agha, Riaz A.; Fowler, Alexander J.; Sevdalis, Nick

    2015-01-01

    Non-technical skills are of increasing importance in surgery and surgical training. A traditional focus on technical skills acquisition and competence is no longer enough for the delivery of a modern, safe surgical practice. This review discusses the importance of non-technical skills and the values that underpin successful modern surgical practice. This narrative review used a number of sources including written and online, there was no specific search strategy of defined databases. Modern surgical practice requires; technical and non-technical skills, evidence-based practice, an emphasis on lifelong learning, monitoring of outcomes and a supportive institutional and health service framework. Finally these requirements need to be combined with a number of personal and professional values including integrity, professionalism and compassionate, patient-centred care. PMID:26904193

  1. Technical Efficiency Performance of Conventional Banks

    OpenAIRE

    Endri, Endri

    2012-01-01

    This study aims to measure the performance of the technical efficiency of the conventional commercial banks during the period 2008-2009 by using non-parametric method of Data Envelopment Analysis (DEA). Test results showed that the total of all conventional commercial banks during the period 2008-2009 has not shown that optimal performance in which the level of technical efficiency is still below 100 percent. Appalling conditions, the efficiency of national banks experienced a decline of 73.5...

  2. Foam-Delivery of Remedial Amendments for Enhanced Vadose Zone Metals and Radionuclides Remediation

    International Nuclear Information System (INIS)

    Zhong, L.; Szecsody, J.E.; Dresel, P.E.; Zhang, Z.F.; Qafoku, N.P.

    2009-01-01

    The remediation of metals and radionuclides contamination, such as Cr(VI), Tc-99, and Sr-90 in the U.S. DOE Hanford Site vadose zone is a critical need. Water-based remedial amendments delivery to the deep vadose zone is facing significant technical challenges. Water-based delivery will easily leach out the highly mobile pollutants therefore contaminate the underlying aquifer. Preferential flow of the amendment-laden solution in the vadose zone due to the formation heterogeneity is difficult to overcome, resulting in bypassing of the less permeable zones. Foam has unique transport properties in the vadose zone that enable mitigation on the mobilization of mobile contaminants and enhance the sweeping over heterogeneous systems. Calcium polysulfide (CPS) is a remedial amendment that can be used to reduce and immobilize hexavalent chromium [Cr(VI)] and other redox-sensitive radionuclides/metals in the vadose zone. The delivery of CPS to the vadose zone using foam and the immobilization of Cr(VI) via reduction by the foam-delivered CPS was investigated in this study. Batch tests were conducted to select the foam-generating CPS-surfactant solutions, to determine the solution foamability and the reducing potential of CPS-containing foams, and to study the influence of foam quality, surfactant concentration, and CPS concentration on foam stability. Column experiments were performed to test the foam delivery of CPS to sediments under conditions similar to field vadose zone, to study the foam transport and interaction with sediments, and to determine the extent of Cr(VI) immobilization using this novel delivery approach. CPS-containing foams with high reducing potential were prepared based on the batch tests. Sediment reduction by foam-delivered CPS was observed in the column studies. Significant mobilization of Cr(VI) from sediments occurred when CPS was delivered in aqueous solution. The Cr(VI) mobilization was minimized when CPS was delivered by foams, resulting in

  3. Linac4 Technical Design Report

    CERN Document Server

    Arnaudon, L; Baylac, M; Bellodi, G; Body, Y; Borburgh, J; Bourquin, P; Broere, J; Brunner, O; Bruno, L; Carli, C; Caspers, Friedhelm; Cousineau, S M; Cuvet, Y; De Almeida Martins, C; Dobers, T; Fowler, T; Garoby, R; Gerigk, F; Goddard, B; Hanke, K; Hori, M; Jones, M; Kahle, K; Kalbreier, Willi; Kroyer, T; Küchler, D; Lombardi, A M; López-Hernandez, L A; Magistris, M; Martini, M; Maury, S; Page, E; Paoluzzi, M; Pasini, M; Raich, U; Rossi, C; Royer, J P; Sargsyan, E; Serrano, J; Scrivens, R; Silari, M; Timmins, M; Venturini-Delsolaro, W; Vretenar, M; Wegner, R; Weterings, W; Zickler, T

    2006-01-01

    Linac4 is an H- linear accelerator, intended to replace Linac2 as injector to the PS Booster (PSB). By delivering to the PSB a beam at 160 MeV energy, Linac4 will provide the conditions to double the brightness and intensity of the beam from the PSB, thus removing the first bottleneck towards higher brightness for the LHC and simplifying operation. Moreover, this new linac constitutes an essential component of any of the envisaged LHC upgrade scenarios and could open the way to future extensions of the CERN accelerator complex towards higher performance. This Technical Design Report presents a detailed technical overview of the Linac4 design as it stands at end 2006.

  4. Redefining continuing education delivery.

    Science.gov (United States)

    Carlton, K H

    1997-01-01

    Just as technology is transforming the delivery of education, the Internet and advanced telecommunication applications are changing the "face" of CE and the connotation of "lifelong learning." As late as the mid-1980s, a discussion of computer applications in nursing CE focused on the "timely" transition to microcomputers as tools for the enhancement of managerial tasks for increased productivity. Even as recently as 1990, there seemed to be "time" for those providers who were "slower to adopt innovation" to "catch up." Now, the CE provider who does not integrate the microcomputer and advanced telecommunications as an integral component of their delivery modalities may be outsourced rapidly by an educational or commercial competitive unit that is able to utilize the communication medium, mergers and partnerships, enterprise, and individual lifestyle and learning patterns that will epitomize the CE unit of the 21st century. As with the "re-engineering" of nursing education, the "re-engineered" delivery modalities of evolving CE entity might now best be conceptualized on a continuum from the traditional mode that time and place dependent to a mode of synchronous and asynchronous data and advanced telecommunication. Delivery methods will need to be selected according to the target populations, content, and situation. The health-care educational provider may discover, as in other industries, that a combination of distance and residential offerings will be the most successful medium for the delivery of CE to the progressively more "information and technologically savvy" lifelong learner of the 21st century. In addressing the dramatic effects of the information technology era on the refocused multimedia/interactive delivery method for student education, educators amply quoted Bob Dylan's phrase of the 1960s, "The times, they are a-changing." And so, we see that the times are also changing at an astronomical rate for the health-care educational provider as well as the

  5. National Profiles in Technical and Vocational Education in Asia and the Pacific: Bhutan.

    Science.gov (United States)

    United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

    This technical and vocational education (TVE) profile on Bhutan is one in a series of profiles of UNESCO member countries. It is intended to be a handy reference on TVE systems, staff development, technical cooperation, and information networking. Part I, Policy Concern, provides general information on the education delivery system, the role of…

  6. Technical Training for Managers.

    Science.gov (United States)

    Haverland, Edgar M.

    The question has arisen as to what kind of information a manager without extensive technical training needs to learn to supervise effectively. For example, the Nike Hercules fire control platoon leader, usually an officer in his first active duty assignment, seldom has had extensive technical training. Yet he is responsibile for the…

  7. Technical Manual. The ACT®

    Science.gov (United States)

    ACT, Inc., 2014

    2014-01-01

    This manual contains technical information about the ACT® college readiness assessment. The principal purpose of this manual is to document the technical characteristics of the ACT in light of its intended purposes. ACT regularly conducts research as part of the ongoing formative evaluation of its programs. The research is intended to ensure that…

  8. Developing Technical Skill Assessments

    Science.gov (United States)

    Hyslop, Alisha

    2009-01-01

    One of the biggest challenges facing the career and technical education (CTE) community as it works to implement the 2006 Perkins Act is responding to more rigorous requirements for reporting on CTE students' technical skill attainment. The U.S. Department of Education suggested in non-regulatory guidance that states and locals use the number of…

  9. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    1998-01-01

    article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply.......article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply....

  10. TRANSLATING SERVICE TECHNICAL PROSE

    African Journals Online (AJOL)

    language. The Application of Technical Service. Prose. To form a good idea of the appl ication .... cost lives. In this particular domain, translators must have a sound technical ... These semantic ... another language and often, in doing so, changing its meaning. The words ..... He will hand out tasks to each translator and after.

  11. Technical Writing Tips

    Science.gov (United States)

    Kennedy, Patrick M.

    2004-01-01

    The main reason engineers, technicians, and programmers write poor technical documents is because they have had little training or experience in that area. This article addresses some of the basics that students can use to master technical writing tasks. The article covers the most common problems writers make and offers suggestions for improving…

  12. Research in Technical Colleges

    Science.gov (United States)

    MacLennan, A.

    2008-01-01

    Purpose: The purpose of this paper is to list and demonstrate areas in which research needs to be carried out, or questions answered, in order to raise the quality of technical education. Design/methodology/approach: The area of technical education expanded very rapidly in the late 1950s, and there was little comprehensive knowledge regarding the…

  13. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Glasser, Alan H. [Fusion Theory and Computation Inc., Kingston, WA (United States)

    2018-02-02

    Final technical report on DE-SC0016106. This is the final technical report for a portion of the multi-institutional CEMM project. This report is centered around 3 publications and a seminar presentation, which have been submitted to E-Link.

  14. Technical Agency in Practice

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    2015-01-01

    ) description of hybrid networks in which human and non-human actants are granted agency without differentiating different kinds of agency, EMCA focuses on the member's perspectives and the situated construction of technical agency that is made relevant within an ongoing interaction. Based on an EMCA analysis......The paper combines the discussion of technical agency and hybrid networks of Actor-Network Theory (ANT) with an ethnomethodological/conversation analytical (EMCA) perspective on situated practices in which participants ascribe agency to technical artefacts. While ANT works with (ethnographic...... of three video recordings of situations in which technical agency is made relevant by the human participants, the paper demonstrates different ways in which agency is granted to technical artefacts. Human participants can treat a technology as communication partner, as an active part (and actant...

  15. Ethical issues in cesarean delivery.

    Science.gov (United States)

    Chervenak, Frank A; McCullough, Laurence B

    2017-08-01

    Cesarean delivery is the most common and important surgical intervention in obstetric practice. Ethics provides essential guidance to obstetricians for offering, recommending, recommending against, and performing cesarean delivery. This chapter provides an ethical framework based on the professional responsibility model of obstetric ethics. This framework is then used to address two especially ethically challenging clinical topics in cesarean delivery: patient-choice cesarean delivery and trial of labor after cesarean delivery. This chapter emphasizes a preventive ethics approach, designed to prevent ethical conflict in clinical practice. To achieve this goal, a preventive ethics approach uses the informed consent process to offer cesarean delivery as a medically reasonable alternative to vaginal delivery, to recommend cesarean delivery, and to recommend against cesarean delivery. The limited role of shared decision making is also described. The professional responsibility model of obstetric ethics guides this multi-faceted preventive ethics approach. Copyright © 2017. Published by Elsevier Ltd.

  16. Health Care Delivery.

    Science.gov (United States)

    Starfield, Barbara

    1987-01-01

    The article reviews emerging health care delivery options for handicapped children. Cost structures, quality of care, and future prospects are considered for Health Maintenance Organizations, Preferred Provider Organizations, Tax Supported Direct Service Programs, Hospital-Based Services, and Ambulatory Care Organizations. (Author/DB)

  17. Drug delivery and formulations.

    Science.gov (United States)

    Breitkreutz, Jörg; Boos, Joachim

    2011-01-01

    Paediatric drug delivery is a major challenge in drug development. Because of the heterogeneous nature of the patient group, ranging from newborns to adolescents, there is a need to use appropriate excipients, drug dosage forms and delivery devices for different age groups. So far, there is a lack of suitable and safe drug formulations for children, especially for the very young and seriously ill patients. The new EU legislation will enforce paediatric clinical trials and drug development. Current advances in paediatric drug delivery include interesting new concepts such as fast-dissolving drug formulations, including orodispersible tablets and oral thin strips (buccal wafers), and multiparticulate dosage forms based on mini-tabletting or pelletization technologies. Parenteral administration is likely to remain the first choice for children in the neonatal period and for emergency cases. Alternative routes of administration include transdermal, pulmonary and nasal drug delivery systems. A few products are already available on the market, but others still need further investigations and clinical proof of concept.

  18. Drug delivery through microneedles

    NARCIS (Netherlands)

    Luttge, R.; Dietzel, A.

    2016-01-01

    Drug delivery through microneedles is a new form of a pharmaceutical dosage system. While single microneedles have been clinically applied already, the out-of-plane integration of a multitude of microneedles in a pharmaceutical patch is a disruptive technology. To take advantage of micro- and

  19. A Medical Delivery Device

    DEFF Research Database (Denmark)

    2010-01-01

    The present invention relates to a medical delivery device comprising at least two membrane electrode assembly units each of which comprises three layers: an upper and a lower electrode and a selective ionic conductive membrane provided there-between. At least one of the three layers are shared...

  20. Global Delivery Models

    DEFF Research Database (Denmark)

    Manning, Stephan; Møller Larsen, Marcus; Bharati, Pratyush M.

    2015-01-01

    antecedents and contingencies of setting up GDM structures. Based on comprehensive data we show that providers are likely to establish GDM location configurations when clients value access to globally distributed talent and speed of service delivery, in particular when services are highly commoditized...

  1. Technical basis document for natural event hazards

    International Nuclear Information System (INIS)

    CARSON, D.M.

    2003-01-01

    This technical basis document was developed to support the Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process and the technical basis for assigning risk bins for natural event hazards (NEH)-initiated representative accident and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous conditions based on an evaluation of the frequency and consequence. Note that the risk binning process is not applied to facility workers, because all facility worker hazardous conditions are considered for safety-significant SSCs and/or TSR-level controls. Determination of the need for safety-class SSCs was performed in accordance with DOE-STD-3009-94, ''Preparation Guide for US Department of Energy Nonreactor Nuclear Facility Documented Safety Analyses'', as described in this report

  2. Topical and transdermal drug delivery: principles and practice

    National Research Council Canada - National Science Library

    Benson, Heather A. E; Watkinson, Adam C

    2012-01-01

    .... Providing an overview of the current science in drug and cosmetic application to and through the skin, Topical and Transdermal Drug Delivery includes treatment of skin conditions, skin permeation...

  3. original article predictors of safe delivery service utilization in arsi

    African Journals Online (AJOL)

    Abrham

    There is limited information on the mothers' use of skilled delivery services in the ... to conditions related to pregnancy and child birth. 99% of .... having favourable attitude towards utilization of ... two injections of Tetanus Toxoid vaccine during.

  4. Relationship between non-technical skills and technical performance during cardiopulmonary resuscitation: does stress have an influence?

    Science.gov (United States)

    Krage, Ralf; Zwaan, Laura; Tjon Soei Len, Lian; Kolenbrander, Mark W; van Groeningen, Dick; Loer, Stephan A; Wagner, Cordula; Schober, Patrick

    2017-11-01

    Non-technical skills, such as task management, leadership, situational awareness, communication and decision-making refer to cognitive, behavioural and social skills that contribute to safe and efficient team performance. The importance of these skills during cardiopulmonary resuscitation (CPR) is increasingly emphasised. Nonetheless, the relationship between non-technical skills and technical performance is poorly understood. We hypothesise that non-technical skills become increasingly important under stressful conditions when individuals are distracted from their tasks, and investigated the relationship between non-technical and technical skills under control conditions and when external stressors are present. In this simulator-based randomised cross-over study, 30 anaesthesiologists and anaesthesia residents from the VU University Medical Center, Amsterdam, the Netherlands, participated in two different CPR scenarios in random order. In one scenario, external stressors (radio noise and a distractive scripted family member) were added, while the other scenario without stressors served as control condition. Non-technical performance of the team leader and technical performance of the team were measured using the 'Anaesthetists' Non-technical Skill' score and a recently developed technical skills score. Analysis of variance and Pearson correlation coefficients were used for statistical analyses. Non-technical performance declined when external stressors were present (adjusted mean difference 3.9 points, 95% CI 2.4 to 5.5 points). A significant correlation between non-technical and technical performance scores was observed when external stressors were present (r=0.67, 95% CI 0.40 to 0.83, ptechnical performance score (task management, team working, situation awareness, decision-making). During CPR with external stressors, the team's technical performance is related to the non-technical skills of the team leader. This may have important implications for training of

  5. Urology technical and non-technical skills development: the emerging role of simulation.

    Science.gov (United States)

    Rashid, Prem; Gianduzzo, Troy R J

    2016-04-01

    To review the emerging role of technical and non-technical simulation in urological education and training. A review was conducted to examine the current role of simulation in urology training. A PUBMED search of the terms 'urology training', 'urology simulation' and 'urology education' revealed 11,504 titles. Three hundred and fifty-seven abstracts were identified as English language, peer reviewed papers pertaining to the role of simulation in urology and related topics. Key papers were used to explore themes. Some cross-referenced papers were also included. There is an ongoing need to ensure that training time is efficiently utilised while ensuring that optimal technical and non-technical skills are achieved. Changing working conditions and the need to minimise patient harm by inadvertent errors must be taken into account. Simulation models for specific technical aspects have been the mainstay of graduated step-wise low and high fidelity training. Whole scenario environments as well as non-technical aspects can be slowly incorporated into the curriculum. Doing so should also help define what have been challenging competencies to teach and evaluate. Dedicated time, resources and trainer up-skilling are important. Concurrent studies are needed to help evaluate the effectiveness of introducing step-wise simulation for technical and non-technical competencies. Simulation based learning remains the best avenue of progressing surgical education. Technical and non-technical simulation could be used in the selection process. There are good economic, logistic and safety reasons to pursue the process of ongoing development of simulation co-curricula. While the role of simulation is assured, its progress will depend on a structured program that takes advantage of what can be delivered via this medium. Overall, simulation can be developed further for urological training programs to encompass technical and non-technical skill development at all stages, including

  6. Protein-Based Drug-Delivery Materials

    Directory of Open Access Journals (Sweden)

    Dave Jao

    2017-05-01

    Full Text Available There is a pressing need for long-term, controlled drug release for sustained treatment of chronic or persistent medical conditions and diseases. Guided drug delivery is difficult because therapeutic compounds need to survive numerous transport barriers and binding targets throughout the body. Nanoscale protein-based polymers are increasingly used for drug and vaccine delivery to cross these biological barriers and through blood circulation to their molecular site of action. Protein-based polymers compared to synthetic polymers have the advantages of good biocompatibility, biodegradability, environmental sustainability, cost effectiveness and availability. This review addresses the sources of protein-based polymers, compares the similarity and differences, and highlights characteristic properties and functionality of these protein materials for sustained and controlled drug release. Targeted drug delivery using highly functional multicomponent protein composites to guide active drugs to the site of interest will also be discussed. A systematical elucidation of drug-delivery efficiency in the case of molecular weight, particle size, shape, morphology, and porosity of materials will then be demonstrated to achieve increased drug absorption. Finally, several important biomedical applications of protein-based materials with drug-delivery function—including bone healing, antibiotic release, wound healing, and corneal regeneration, as well as diabetes, neuroinflammation and cancer treatments—are summarized at the end of this review.

  7. Conditioning processes for incinerator ashes

    International Nuclear Information System (INIS)

    Jouan, A.; Ouvrier, N.; Teulon, F.

    1990-01-01

    Three conditioning processes for alpha-bearing solid waste incineration ashes were investigated and compared according to technical and economic criteria: isostatic pressing, cold-crucible direct-induction melting and cement-resin matrix embedding

  8. Towards common technical standards

    International Nuclear Information System (INIS)

    Rahmat, H.; Suardi, A.R.

    1993-01-01

    In 1989, PETRONAS launched its Total Quality Management (TQM) program. In the same year the decision was taken by the PETRONAS Management to introduce common technical standards group wide. These standards apply to the design, construction, operation and maintenance of all PETRONAS installations in the upstream, downstream and petrochemical sectors. The introduction of common company standards is seen as part of an overall technical management system, which is an integral part of Total Quality Management. The Engineering and Safety Unit in the PETRONAS Central Office in Kuala Lumpur has been charged with the task of putting in place a set of technical standards throughout PETRONAS and its operating units

  9. Self-nanoemulsifying drug delivery systems for oral insulin delivery

    DEFF Research Database (Denmark)

    Li, Ping; Tan, Angel; Prestidge, Clive A

    2014-01-01

    This study aims at evaluating the combination of self-nanoemulsifying drug delivery systems (SNEDDS) and enteric-coated capsules as a potential delivery strategy for oral delivery of insulin. The SNEDDS preconcentrates, loaded with insulin-phospholipid complex at different levels (0, 2.5 and 10% w...

  10. Chemistry, manufacturing and controls in passive transdermal drug delivery systems.

    Science.gov (United States)

    Goswami, Tarun; Audett, Jay

    2015-01-01

    Transdermal drug delivery systems (TDDS) are used for the delivery of the drugs through the skin into the systemic circulation by applying them to the intact skin. The development of TDDS is a complex and multidisciplinary affair which involves identification of suitable drug, excipients and various other components. There have been numerous problems reported with respect to TDDS quality and performance. These problems can be reduced by appropriately addressing chemistry, manufacturing and controls requirements, which would thereby result in development of robust TDDS product and processes. This article provides recommendations on the chemistry, manufacturing and controls focusing on the unique technical aspects of TDDS.

  11. Drug delivery via porous silicon: a focused patent review.

    Science.gov (United States)

    Kulyavtsev, Paulina A; Spencer, Roxanne P

    2017-03-01

    Although silicon is more commonly associated with computer chips than with drug delivery, with the discovery that porous silicon is a viable biocompatible material, mesoporous silicon with pores between 2 and 50 nm has been loaded with small molecule and biomolecule therapeutics and safely implanted for controlled release. As porous silicon is readily oxidized, porous silica must also be considered for drug delivery applications. Since 2010, only a limited number of US patents have been granted, primarily for ophthalmologic and immunotherapy applications, in contrast to the growing body of technical literature in this area.

  12. Evaluating Feed Delivery Performance in Scaled Double-Shell Tanks

    International Nuclear Information System (INIS)

    Lee, Kearn P.; Thien, Michael G.

    2013-01-01

    The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capability using simulated Hanford High-Level Waste (HLW) formulations. This work represents one of the remaining technical issues with the high-level waste treatment mission at Hanford. The TOCs' ability to adequately mix and sample high-level waste feed to meet the WTP WAC Data Quality Objectives must be demonstrated. The tank mixing and feed delivery must support both TOC and WTP operations. The tank mixing method must be able to remove settled solids from the tank and provide consistent feed to the WTP to facilitate waste treatment operations. Two geometrically scaled tanks were used with a broad spectrum of tank waste simulants to demonstrate that mixing using two rotating mixer jet pumps yields consistent slurry compositions as the tank is emptied in a series of sequential batch transfers. Testing showed that the concentration of slow settling solids in each transfer batch was consistent over a wide range of tank operating conditions. Although testing demonstrated that the concentration of fast settling solids decreased by up to 25% as the tank was emptied, batch-to-batch consistency improved as mixer jet nozzle velocity in the scaled tanks increased

  13. Intrinsic stability of technical superconductors

    International Nuclear Information System (INIS)

    Veringa, H.J.

    1981-10-01

    For the operation of technical superconductors under high current density conditions, the superconducting wires composing high current cables should be intrinsically stabilized. In this report the various important stability criteria are derived and investigated on their validity. An experimental set up is made to check the occurrence of magnetic instabilities if the different applicable criteria are violated. It is found that the observed instabilities can be predicted on the basis of the model given in this report. Production of high current cables based upon composites made by the ECN technique seems to be possible. (Auth.)

  14. RAMP 2005 technical report

    International Nuclear Information System (INIS)

    2006-01-01

    This technical report provided details of all monitoring activities conducted by the Regional Aquatics Monitoring Program (RAMP), which was initiated in 1997 to examine the impacts of oil sands mining development on aquatic systems in the region. RAMP's objective is to integrate aquatic monitoring activities in order to identify long-term trends and regional issues related to the environment in the Regional Municipality of Wood Buffalo. In 2005, RAMP focused on key components of boreal aquatic ecosystems. This report provided full outlines of all climate and hydrology monitoring activities; water and sedimentation analyses; and studies of benthic communities in rivers, lakes, and deltas. Sets of measurements endpoints were used to represent the health and integrity of valued environmental resources. Satellite imager was used to estimate activities related to oil sands developments. The report was divided into subsections which related monitoring activities for various rivers and tributaries in the region. Small and negligible calculated changes were observed in hydrologic conditions in the Athabasca River mainstem. No discernible changes in water and sediment quality were observed that could positively be ascribed to oil sands developments in the region. Very little evidence suggested that fish populations had changed as a result of increased activities in the region. The influence of oil sands development activities on the aquatic resources of the Athabasca River mainstem were minor and mostly undetectable. The results of fish tissue studies from the lower Athabasca River showed that concentrations of mercury in fish tissues occurred at levels that posed a high risk to subsistence fishers. A higher number of metal concentrations in some lakes in the region was attributed to natural causes. The results of a sentinel species monitoring program conducted at the Ells River watershed were also included. Recommendations for further refining RAMP programs were also

  15. Technical standards in nuclear area

    International Nuclear Information System (INIS)

    Grimberg, M.

    1978-01-01

    The technical standardization in nuclear area is discussed. Also, the competence of CNEN in standardization pursuit is analysed. Moreover, the process of working up of technical standards is explained; in addition, some kinds of technical standards are discussed. (author) [pt

  16. SAM Technical Contacts

    Science.gov (United States)

    These technical contacts are available to help with questions regarding method deviations, modifications, sample problems or interferences, quality control requirements, the use of alternative methods, or the need to address analytes or sample types.

  17. INDOT Technical Training Plan

    Science.gov (United States)

    2012-04-01

    The study provides the background documents necessary for the development of a Technical Training Plan and makes recommendations : for the content and structure of such a plan for the District Operations, Operations, Capital Program Management, and E...

  18. social & technical innovations

    International Development Research Centre (IDRC) Digital Library (Canada)

    CHANGE: GAPS BRIDGED BY SMART SOLUTIONS. CHALLENGE: INABILITY TO REACH THOSE IN NEED. SOLAR PANELS. OVERCOME POWER. SUPPLY CHALLENGES. IN BURKINA FASO. SOCIAL & TECHNICAL. INNOVATIONS. BANGLADESH BURKINA FASO ETHIOPIA KENYA LEBANON PERU VIETNAM.

  19. Superfund Technical Assistance Grants

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes data related to the Superfund Technical Assistance Grant program, including grant number, award amounts, award dates, period of performance,...

  20. OSH technical reference manual

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinent to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.

  1. NCDC Technical Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCDC Technical Reports is a set of retrospective analyses produced by the Research Customer Service Group and the National Climatic Data Center from 1995 to 2008....

  2. Socio-technical Betwixtness

    DEFF Research Database (Denmark)

    Bossen, Claus

    2017-01-01

    the intrinsically social and technical interwovenness of design, and the necessity of including affected people and stakeholders in the design process. This betwixtness of socio-technical design is demonstrated by the analysis of two IT systems for healthcare: a foundational model for electronic healthcare records......This chapter focusses on two challenges for socio-technical design: Having to choose between different rationales for design, and the adequate understanding and depiction of the work to be redesigned. These two challenges betwixt the otherwise strong tenets of socio-technical design of pointing out......, and an IT system organizing hospital porters’ work. The conceptual background for the analysis of the cases is provided by a short introduction to different rationales for organizational design, and by pointing to the differences between a linear, rationalistic versus an interactional depiction of work....

  3. Technical report writing today

    CERN Document Server

    Riordan, Daniel G

    2014-01-01

    "Technical Report Writing Today" provides thorough coverage of technical writing basics, techniques, and applications. Through a practical focus with varied examples and exercises, students internalize the skills necessary to produce clear and effective documents and reports. Project worksheets help students organize their thoughts and prepare for assignments, and focus boxes highlight key information and recent developments in technical communication. Extensive individual and collaborative exercises expose students to different kinds of technical writing problems and solutions. Annotated student examples - more than 100 in all - illustrate different writing styles and approaches to problems. Numerous short and long examples throughout the text demonstrate solutions for handling writing assignments in current career situations. The four-color artwork in the chapter on creating visuals keeps pace with contemporary workplace capabilities. The Tenth Edition offers the latest information on using electronic resum...

  4. The technical supervision interface

    CERN Document Server

    Sollander, P

    1998-01-01

    The Technical Control Room (TCR) is currently using 30 different applications for the remote supervision of the technical infrastructure at CERN. These applications have all been developed with the CERN made Uniform Man Machine Interface (UMMI) tools built in 1990. However, the visualization technology has evolved phenomenally since 1990, the Technical Data Server (TDS) has radically changed our control system architecture, and the standardization and the maintenance of the UMMI applications have become important issues as their number increases. The Technical Supervision Interface is intended to replace the UMMI and solve the above problems. Using a standard WWW-browser for the display, it will be inherently multi-platform and hence available for control room operators, equipment specialists and on-call personnel.

  5. Supplier Cooperation in Drone Delivery

    OpenAIRE

    Sawadsitang, Suttinee; Niyato, Dusit; Siew, Tan Puay; Wang, Ping

    2018-01-01

    Recently, unmanned aerial vehicles (UAVs), also known as drones, has emerged as an efficient and cost-effective solution for package delivery. Especially, drones are expected to incur lower cost, and achieve fast and environment friendly delivery. While most of existing drone research concentrates on surveillance applications, few works studied the drone package delivery planning problem. Even so, the previous works only focus on the drone delivery planning of a single supplier. In this paper...

  6. Floating Microparticulate Oral Diltiazem Hydrochloride Delivery ...

    African Journals Online (AJOL)

    Delivery System for Improved Delivery to Heart ... Conclusion: Microparticulate floating (gastroretentive) oral drug delivery system of diltiazem prepared ..... treatment of cardiac disease. ... hydrochloride-loaded mucoadhesive microspheres.

  7. Supersaturating drug delivery systems

    DEFF Research Database (Denmark)

    Laitinen, Riikka; Löbmann, Korbinian; Grohganz, Holger

    2017-01-01

    of the bioavailability of poorly water-soluble drugs by increasing the driving force for drug absorption. However, ASDs often require a high weight percentage of carrier (usually a hydrophilic polymer) to ensure molecular mixing of the drug in the carrier and stabilization of the supersaturated state, often leading......Amorphous solid dispersions (ASDs) are probably the most common and important supersaturating drug delivery systems for the formulation of poorly water-soluble compounds. These delivery systems are able to achieve and maintain a sustained drug supersaturation which enables improvement...... strategy for poorly-soluble drugs. While the current research on co-amorphous formulations is focused on preparation and characterization of these systems, more detailed research on their supersaturation and precipitation behavior and the effect of co-formers on nucleation and crystal growth inhibition...

  8. Pyomyositis after vaginal delivery.

    LENUS (Irish Health Repository)

    Gaughan, Eve

    2011-01-01

    Pyomyositis is a purulent infection of skeletal muscle that arises from haematogenous spread, usually with abscess formation. It can develop after a transient bacteraemia of any cause. This type of infection has never been reported before in the literature after vaginal delivery. A 34-year-old woman had progressive severe pain in the left buttock and thigh and weakness in the left lower limb day 1 post spontaneous vaginal delivery. MRI showed severe oedema of the left gluteus, iliacus, piriformis and adductor muscles of the left thigh and a small fluid collection at the left hip joint. She was diagnosed with pyomyositis. She had fever of 37.9°C immediately postpartum and her risk factors for bacteraemia were a mild IV cannula-associated cellulitis and labour itself. She required prolonged treatment with antibiotics before significant clinical improvement was noted.

  9. Social video content delivery

    CERN Document Server

    Wang, Zhi; Zhu, Wenwu

    2016-01-01

    This brief presents new architecture and strategies for distribution of social video content. A primary framework for socially-aware video delivery and a thorough overview of the possible approaches is provided. The book identifies the unique characteristics of socially-aware video access and social content propagation, revealing the design and integration of individual modules that are aimed at enhancing user experience in the social network context. The change in video content generation, propagation, and consumption for online social networks, has significantly challenged the traditional video delivery paradigm. Given the massive amount of user-generated content shared in online social networks, users are now engaged as active participants in the social ecosystem rather than as passive receivers of media content. This revolution is being driven further by the deep penetration of 3G/4G wireless networks and smart mobile devices that are seamlessly integrated with online social networking and media-sharing s...

  10. Mucoadhesive drug delivery systems

    Directory of Open Access Journals (Sweden)

    Rahamatullah Shaikh

    2011-01-01

    Full Text Available Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for improved therapeutic outcome. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. The mucoadhesive ability of a dosage form is dependent upon a variety of factors, including the nature of the mucosal tissue and the physicochemical properties of the polymeric formulation. This review article aims to provide an overview of the various aspects of mucoadhesion, mucoadhesive materials, factors affecting mucoadhesion, evaluating methods, and finally various mucoadhesive drug delivery systems (buccal, nasal, ocular, gastro, vaginal, and rectal.

  11. Peptide and protein delivery using new drug delivery systems.

    Science.gov (United States)

    Jain, Ashish; Jain, Aviral; Gulbake, Arvind; Shilpi, Satish; Hurkat, Pooja; Jain, Sanjay K

    2013-01-01

    Pharmaceutical and biotechnological research sorts protein drug delivery systems by importance based on their various therapeutic applications. The effective and potent action of the proteins/peptides makes them the drugs of choice for the treatment of numerous diseases. Major research issues in protein delivery include the stabilization of proteins in delivery devices and the design of appropriate target-specific protein carriers. Many efforts have been made for effective delivery of proteins/peptidal drugs through various routes of administrations for successful therapeutic effects. Nanoparticles made of biodegradable polymers such as poly lactic acid, polycaprolactone, poly(lactic-co-glycolic acid), the poly(fumaric-co-sebacic) anhydride chitosan, and modified chitosan, as well as solid lipids, have shown great potential in the delivery of proteins/peptidal drugs. Moreover, scientists also have used liposomes, PEGylated liposomes, niosomes, and aquasomes, among others, for peptidal drug delivery. They also have developed hydrogels and transdermal drug delivery systems for peptidal drug delivery. A receptor-mediated delivery system is another attractive strategy to overcome the limitation in drug absorption that enables the transcytosis of the protein across the epithelial barrier. Modification such as PEGnology is applied to various proteins and peptides of the desired protein and peptides also increases the circulating life, solubility and stability, pharmacokinetic properties, and antigenicity of protein. This review focuses on various approaches for effective protein/peptidal drug delivery, with special emphasis on insulin delivery.

  12. Nanocarriers in ocular drug delivery: an update review.

    Science.gov (United States)

    Wadhwa, Sheetu; Paliwal, Rishi; Paliwal, Shivani Rai; Vyas, S P

    2009-01-01

    Controlled drug delivery to eye is one of the most challenging fields of pharmaceutical research. Low drug-contact time and poor ocular bioavailability due to drainage of solution, tear turnover and its dilution or lacrimation are the problems associated with conventional systems. In addition, anatomical barriers and physiological conditions of eye are also important parameters which control designing of drug delivery systems. Nanosized carriers like micro/nano-suspensions, liposome, niosome, dendrimer, nanoparticles, ocular inserts, implants, hydrogels and prodrug approaches have been developed for this purpose. These novel systems offer manifold advantages over conventional systems as they increase the efficiency of drug delivery by improving the release profile and also reduce drug toxicity. Conventional delivery systems get diluted with tear, washed away through the lacrimal gland and usually require administering at regular time intervals whereas nanocarriers release drug at constant rate for a prolonged period of time and thus enhance its absorption and site specific delivery. This review presents an overview of the various aspects of the ocular drug delivery, with special emphasis on nanocarrier based strategies, including structure of eye, its barriers, delivery routes and the challenges/limitations associated with development of novel nanocarriers. The recent progresses in therapy of ocular disease like gene therapy have also been included so that future options should also be considered from the delivery point of view. Recent progress in the delivery of proteins and peptides via ocular route has also been incorporated for reader benefit.

  13. Training for Technical Assistants: Technical Assistance Program

    Science.gov (United States)

    1986-09-01

    shortage of technical ptfesson until such time as English , "speking instructors might be trained, There. would be An aumcation of committed on-calI...12 hours in classroom Instruction, students in English as a Second nel Research and Development Computer.taught students Language. The program Is...hbeels "p.-ogram. A Iot ’ atar boiler arn tank heats týe food enroute to its destination. 1.0. A new tor of dust ptectleon to protect machine .perators

  14. Handling, treatment, conditioning and storage of biological radioactive wastes. Technical manual for the management of low and intermediate level wastes generated at small nuclear research centres and by radioisotope users in medicine, research and industry

    International Nuclear Information System (INIS)

    1994-12-01

    Biological materials that contain radioactive isotopes have many important applications. During the production and use of these materials, waste will inevitably arise which must be managed with particular care due to their potential biological as well as radiological hazards. This report deals with wastes that arise outside the nuclear fuel cycle and is directed primarily to countries without nuclear power programmes. It is intended to provide guidance to Member States in the handling, treatment and conditioning of biological radioactive materials. The objective of radioactive waste management is to handle, pretreat, treat, condition, store, transport and dispose of radioactive waste in a manner that protects human health and the environment without imposing undue burdens on future generations. 31 refs, 15 figs, 3 tabs

  15. Handling, treatment, conditioning and storage of biological radioactive wastes. Technical manual for the management of low and intermediate level wastes generated at small nuclear research centres and by radioisotope users in medicine, research and industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    Biological materials that contain radioactive isotopes have many important applications. During the production and use of these materials, waste will inevitably arise which must be managed with particular care due to their potential biological as well as radiological hazards. This report deals with wastes that arise outside the nuclear fuel cycle and is directed primarily to countries without nuclear power programmes. It is intended to provide guidance to Member States in the handling, treatment and conditioning of biological radioactive materials. The objective of radioactive waste management is to handle, pretreat, treat, condition, store, transport and dispose of radioactive waste in a manner that protects human health and the environment without imposing undue burdens on future generations. 31 refs, 15 figs, 3 tabs.

  16. Using a non-invasive technique in nutrition: synchrotron radiation infrared microspectroscopy spectroscopic characterization of oil seeds treated with different processing conditions on molecular spectral factors influencing nutrient delivery.

    Science.gov (United States)

    Zhang, Xuewei; Yu, Peiqiang

    2014-07-02

    Non-invasive techniques are a key to study nutrition and structure interaction. Fourier transform infrared microspectroscopy coupled with a synchrotron radiation source (SR-IMS) is a rapid, non-invasive, and non-destructive bioanalytical technique. To understand internal structure changes in relation to nutrient availability in oil seed processing is vital to find optimal processing conditions. The objective of this study was to use a synchrotron-based bioanalytical technique SR-IMS as a non-invasive and non-destructive tool to study the effects of heat-processing methods and oil seed canola type on modeled protein structure based on spectral data within intact tissue that were randomly selected and quantify the relationship between the modeled protein structure and protein nutrient supply to ruminants. The results showed that the moisture heat-related processing significantly changed (pprocessing by dry heating. The moisture heating increased (p0.05) in the protein spectral profile between the raw and dry-heated canola tissue and between yellow- and brown-type canola tissue. The results indicated that different heat processing methods have different impacts on the protein inherent structure. The protein intrinsic structure in canola seed tissue was more sensitive and more response to the moisture heating in comparison to the dry heating. These changes are expected to be related to the nutritive value. However, the current study is based on limited samples, and more large-scale studies are needed to confirm our findings.

  17. TECHNICAL BASIS DOCUMENT FOR NATURAL EVENT HAZARDS

    International Nuclear Information System (INIS)

    KRIPPS, L.J.

    2006-01-01

    This technical basis document was developed to support the documented safety analysis (DSA) and describes the risk binning process and the technical basis for assigning risk bins for natural event hazard (NEH)-initiated accidents. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous conditions based on an evaluation of the frequency and consequence. Note that the risk binning process is not applied to facility workers, because all facility worker hazardous conditions are considered for safety-significant SSCs and/or TSR-level controls

  18. 78 FR 27963 - Reliability Technical Conference; Notice of Technical Conference

    Science.gov (United States)

    2013-05-13

    ... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, July 9, 2013 from 9:00 a.m. to 5:00 p.m. This... technical support for webcasts and offers the option of listening to the meeting via phone-bridge for a fee...

  19. 76 FR 64083 - Reliability Technical Conference; Notice of Technical Conference

    Science.gov (United States)

    2011-10-17

    ... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, November 29, 2011, from 1 p.m. to 5 p.m. and... reliability that were identified in earlier Commission technical conferences. The conference also will discuss...

  20. Power plants in competition 2011. Perspectives of future generation portfolio. Technology-system, stability-market, conditions, with technical exhibition; Kraftwerke im Wettbewerb 2011. Perspektiven des kuenftigen Erzeugungs-Portfolios. Technologie, Systemstabilitaet, Marktbedingungen, mit Fachausstellung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The proceedings on the VGB conference ''power plants in competition 2011'' includes the following contributions: status of European energy policy; market and climate protection; setting up new conventional capacity in Europe and EU regulation; perspectives of power generation in Germany and Europe; market for power generation - challenges and chances for suppliers; development of a European ''network code'' for integration of power plants; impact of ''EU network code'' for design and operation of power plants; outcome of investigation of grid/generation; impact of intermitting generation on power system stability; consequences of low-load operation for coal fired power plants; pro quality - an approach for project management; Sumitomos R and D activities for advanced USC boilers; V and M innovative contribution to the challenges of present and future conventional power plants; steam side oxidation at austenitic boiler tubes; OL3 project - a multicultural challenge; knowledge management - preservation and maintenance of implicit knowledge within a company; competition about green investments - the European targets for renewables; retrofitting of CEZ power plants (coal and gas); power sector skill - addressing the challenges; requirements on structural maintenance in power plants; usage of corrugated tubes in heat exchangers; technical plant documentation; technologies for off-shore wind turbines; solar thermal plants; renewable energy from biomass and integration into the grid; environmentally friendly future power generation with fossil fuels; storage technologies; large-scale underground energy storage; assessment of risk - an insurance company view; human resources as multiplier for a company's value; post-combustion capture pilot plant experiences; CCS strategy of Vattenfall; optimizing plant process management; Enel activities on carbon capture and sequestration; bachelor studies on power plant

  1. Pregnancy and Vaginal Delivery after Sacrohysteropexy

    Directory of Open Access Journals (Sweden)

    Deniz Balsak

    2015-01-01

    Full Text Available Pregnancy and birth after a Pelvic Organ Prolapse (POP surgery is a rare condition and less is known about the method for delivery. A 31-year-old women with gravida 3 para 3 underwent abdominal sacrohysteropexy and transobturatuar tape (TOT procedures for stage III prolapse who delivered via vaginal birth and showed no relapse. Sacrohysteropexy is a good option for women with POP who desire fertility with a long term follow-up period.

  2. Canister Storage Building (CSB) Technical Safety Requirements

    International Nuclear Information System (INIS)

    KRAHN, D.E.

    2000-01-01

    The purpose of this section is to explain the meaning of logical connectors with specific examples. Logical connectors are used in Technical Safety Requirements (TSRs) to discriminate between, and yet connect, discrete Conditions, Required Actions, Completion Times, Surveillances, and Frequencies. The only logical connectors that appear in TSRs are AND and OR. The physical arrangement of these connectors constitutes logical conventions with specific meanings

  3. Development of technical specifications for research reactors

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    This standard identifies and establishes the content of technical specifications for research reactors. Areas addressed are: definitions, safety limits, limiting safety system settings, limiting conditions for operation, surveillance requirements, design features and administrative controls. Sufficient detail is incorporated so that applicable specifications can be derived or extracted

  4. Far-Field Acoustic Power Level and Performance Analyses of F31/A31 Open Rotor Model at Simulated Scaled Takeoff, Nominal Takeoff, and Approach Conditions: Technical Report I

    Science.gov (United States)

    Sree, Dave

    2015-01-01

    Far-field acoustic power level and performance analyses of open rotor model F31/A31 have been performed to determine its noise characteristics at simulated scaled takeoff, nominal takeoff, and approach flight conditions. The nonproprietary parts of the data obtained from experiments in 9- by 15-Foot Low-Speed Wind Tunnel (9?15 LSWT) tests were provided by NASA Glenn Research Center to perform the analyses. The tone and broadband noise components have been separated from raw test data by using a new data analysis tool. Results in terms of sound pressure levels, acoustic power levels, and their variations with rotor speed, angle of attack, thrust, and input shaft power have been presented and discussed. The effect of an upstream pylon on the noise levels of the model has been addressed. Empirical equations relating model's acoustic power level, thrust, and input shaft power have been developed. The far-field acoustic efficiency of the model is also determined for various simulated flight conditions. It is intended that the results presented in this work will serve as a database for comparison and improvement of other open rotor blade designs and also for validating open rotor noise prediction codes.

  5. Analysis of Market Opportunities for Chinese Private Express Delivery Industry

    Science.gov (United States)

    Jiang, Changbing; Bai, Lijun; Tong, Xiaoqing

    China's express delivery market has become the arena in which each express enterprise struggles to chase due to the huge potential demand and high profitable prospects. So certain qualitative and quantitative forecast for the future changes of China's express delivery market will help enterprises understand various types of market conditions and social changes in demand and adjust business activities to enhance their competitiveness timely. The development of China's express delivery industry is first introduced in this chapter. Then the theoretical basis of the regression model is overviewed. We also predict the demand trends of China's express delivery market by using Pearson correlation analysis and regression analysis from qualitative and quantitative aspects, respectively. Finally, we draw some conclusions and recommendations for China's express delivery industry.

  6. Technical training: places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Introduction to VHDL 21-Feb-13 to 22-Feb-13 2 days English Mechanical design Next Session Duration Language ANSYS - Introduction à ANSYS Mechanical APDL 04-Feb-13 to 07-Feb-13 4 days English Applications de la cotation fonctionnelle et du langage ISO 06-Feb-13 to 08-Feb-13 2 days 4 hours French CATIA V5 – Surfacique 14-Jan-13 to 15-Jan-13 2 days French Office software Next Session Duration Language ACCESS 2010 - niveau 2 : ECDL 06-Feb-13 to 07-Feb-13 2 days French Dreamweaver CS3 - Niveau 1 14-Jan-13 to 15-Jan-13 2 d...

  7. Technical training - Places available

    CERN Document Server

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Availability Certified LabVIEW Associate Developer (CLAD) 06-Dec-12 to 06-Dec-12 1 hour English One more place available Compatibilité électromagnetique (CEM): Applications 23-Nov-12 to 23-Nov-12 3.5 hours English 3 places available Compatibilité électromagnétique (CEM): Introduction 23-Nov-12 to 23-Nov-12 3 hours English 43 places available Effets des Radiations sur les composants et systèmes électroniques 11-Dec-12 to 12-Dec-12 1 day 4 hours French 9 places available LabVIEW for beginners ...

  8. Technical training - places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department »Electronics design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 3 places available Foundations of Electromagnetism and Magnet Design (EMAG) 14-Nov-12 to 27-Nov-12 6 days English 20 places available Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 15 places available Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 7 places available LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places available »Mechanical design Next Se...

  9. Problems of technical cooperation

    International Nuclear Information System (INIS)

    Noramli, M.

    1987-01-01

    The main principles of the IAEA technical co-operation program, which intends to answer the requirements of the member states as regards technical assistance, are presented. IAEA offers its assistance in the supervision and financial support of the projects, which promise direct and quick profit to the member states. Projects related to the satisfaction of the main demands of humanity, industrial use, energy generation, radiation protection and other fields, which can promote the contribution of nuclear power generation to the course of peace, protection of health and thriving of states, are among them. 35 million dollars (USA) was allocated for the IAEA technical assistance and realization of the co-operation program in 1987

  10. Fuel Element Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Burley, H.H. [ed.

    1956-08-01

    It is the purpose of the Fuel Element Technical Manual to Provide a single document describing the fabrication processes used in the manufacture of the fuel element as well as the technical bases for these processes. The manual will be instrumental in the indoctrination of personnel new to the field and will provide a single data reference for all personnel involved in the design or manufacture of the fuel element. The material contained in this manual was assembled by members of the Engineering Department and the Manufacturing Department at the Hanford Atomic Products Operation between the dates October, 1955 and June, 1956. Arrangement of the manual. The manual is divided into six parts: Part I--introduction; Part II--technical bases; Part III--process; Part IV--plant and equipment; Part V--process control and improvement; and VI--safety.

  11. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2009-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual session of this course will take place on 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  12. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    , the evolution of large technological systems and theories about organisational and technological transformationprocesses. The empirical work consist of three analysis at three different levels: socio-technical descriptions of each sector, an envestigation of one municipality and envestigations of one workshop......The scope of the project is to investigate the possibillities of - and the barriers for a transformation of technical infrastructure conserning energy, water and waste. It focus on urban ecology as a transformation strategy. The theoretical background of the project is theories about infrastructure...

  13. KSC Technical Capabilities Website

    Science.gov (United States)

    Nufer, Brian; Bursian, Henry; Brown, Laurette L.

    2010-01-01

    This document is the website pages that review the technical capabilities that the Kennedy Space Center (KSC) has for partnership opportunities. The purpose of this information is to make prospective customers aware of the capabilities and provide an opportunity to form relationships with the experts at KSC. The technical capabilities fall into these areas: (1) Ground Operations and Processing Services, (2) Design and Analysis Solutions, (3) Command and Control Systems / Services, (4) Materials and Processes, (5) Research and Technology Development and (6) Laboratories, Shops and Test Facilities.

  14. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  15. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  16. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  17. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced using Windows XP. The next bilingual sessions of this course will take place on December 12, 2008 and January 30, 2009. Register using our catalogue : http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  18. Technical memory 2007

    International Nuclear Information System (INIS)

    2009-01-01

    The technical memory 2007 of the Nuclear Regulatory Authority (ARN) of the Argentine Republic, compiles the papers published in the subject on radiation protection and nuclear safety, and presented in journals, technical reports, congress or meetings of these specialities by personnel of the mentioned institution during 2007. In this edition the documents are presented on: environmental protection; transport of radioactive materials; regulations; research reactors and nuclear power plants; biological radiation effects; therapeutic uses of ionizing radiation and radioprotection of patients; internal dosimetry; physical dosimetry; knowledge management; radioactive waste management [es

  19. Multifunctional Nanoparticles for Drug Delivery Applications Imaging, Targeting, and Delivery

    CERN Document Server

    Prud'homme, Robert

    2012-01-01

    This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. Unlike other books covering nanoparticles used in medical applications, Multifunctional Nanoparticles for Drug Delivery Applications presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

  20. A wireless actuating drug delivery system

    International Nuclear Information System (INIS)

    Jo, Won-Jun; Baek, Seung-Ki; Park, Jung-Hwan

    2015-01-01

    A wireless actuating drug delivery system was devised. The system is based on induction heating for drug delivery. In this study, thermally generated nitrogen gas produced by induction heating of azobisisobutyronitrile (AIBN) was utilized for pressure-driven release of the drug. The delivery device consists of an actuator chamber, a drug reservoir, and a microchannel. A semicircular copper disc (5 and 6 mm in diameter and 100 µm thick), and thermal conductive tape were integrated as the heating element in the actuator chamber. The final device was 2.7 mm thick. 28 µl of drug solution were placed in the reservoir and the device released the drug quickly at the rate of 6 µl s −1 by induction heating at 160 µT of magnetic intensity. The entire drug solution was released and dispersed after subcutaneous implantation under identical experimental condition. This study demonstrates that the device was simply prepared and drug delivery could be achieved by wireless actuation of a thin, pressure-driven actuator. (paper)

  1. Non-technical skills in histopathology: definition and discussion.

    Science.gov (United States)

    Johnston, Peter W; Fioratou, Evie; Flin, Rhona

    2011-09-01

    Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, including histopathologists, and can enhance the quality of practice and delivery of health-care services and thus contribute to patient safety. This review aims to introduce histopathologists to non-technical skills and how these pertain to everyday histopathological practice. Drawing from other domains in medicine, specifically anaesthesia and surgery, a variety of non-technical skills are identified and described in the context of histopathology to illustrate the role each plays, often collectively, in daily practice. The generic non-technical skills are defined as situation awareness, decision-making, communication, teamwork, leadership, managing stress and coping with fatigue. Example scenarios from histopathology are presented and the contributions to outcomes made by non-technical skills are explained. Consideration of these specific non-technical skills as a component in histopathology training may benefit practitioners as well as assuring patient safety. © 2011 Blackwell Publishing Limited.

  2. Dendrimers for Drug Delivery

    Directory of Open Access Journals (Sweden)

    Abhay Singh Chauhan

    2018-04-01

    Full Text Available Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr. Donald Tomalia first published his seminal work on Poly(amidoamine (PAMAM dendrimers in 1985. Application of dendrimers as a drug delivery system started in late 1990s. Dendrimers for drug delivery are employed using two approaches: (i formulation and (ii nanoconstruct. In the formulation approach, drugs are physically entrapped in a dendrimer using non-covalent interactions, whereas drugs are covalently coupled on dendrimers in the nanoconstruct approach. We have demonstrated the utility of PAMAM dendrimers for enhancing solubility, stability and oral bioavailability of various drugs. Drug entrapment and drug release from dendrimers can be controlled by modifying dendrimer surfaces and generations. PAMAM dendrimers are also shown to increase transdermal permeation and specific drug targeting. Dendrimer platforms can be engineered to attach targeting ligands and imaging molecules to create a nanodevice. Dendrimer nanotechnology, due to its multifunctional ability, has the potential to create next generation nanodevices.

  3. [Operative vaginal deliveries training].

    Science.gov (United States)

    Dupuis, O

    2008-12-01

    The appropriate use of forceps, vacuums or spatulas facilitates the rapid delivery of foetuses faced with life-threatening situations. It also makes possible the relief of certain cases of prolonged second-stage labor. In France, operative vaginal delivery (OVD) accounts for approximately 10% of all births. OVD training aims to optimize maternal, as well as neonatal safety. It should enable trainees to indicate or contraindicate an OVD safely, as well as to choose the appropriate instrument, use it correctly, and master quality control principles. Traditional OVD training is confronted with both spatial and time-related limitations. Spatial constraints involve both the teacher and trainee who only have limited visual access to the pelvic canal, and the head of the foetus; the time constraint occurs whenever the OVD occurs in an emergency setting. These limitations have been further aggravated by new constraints: decreasing time dedicated to training (European safety rules prohibit work the day after night duty), increasing litigation, and constraints imposed by society. Training by means of simulation removes such limitations making it possible to both avoid exposing pregnant women to the hazards of traditional training, and adapt the training to the skills of each trainee. OVD training should include forceps, vacuums and the use of spatulas. The OVD skills of obstetricians should be audited regularly on both a personal and a confidential level. Such audits could be based on a method using a simulator. Prospective studies comparing traditional and simulation-based training should be encouraged.

  4. Relevance of Technical Training Institutions Taught Skills to Current ...

    African Journals Online (AJOL)

    Technical education in Kenya is a necessary condition that enables members of society to productively function in technologically rapidly changing society. Technical training institutions have the responsibility to develop skilled Artisans, Craftsmen and Technician for employment in business organizations and industries.

  5. Factors that Influence Women's Technical Skill Development in Outdoor Adventure

    Science.gov (United States)

    Warren, Karen; Loeffler, TA

    2006-01-01

    This article provides a theoretical foundation for understanding women's technical skill development (TSD) in outdoor adventure. An examination of societal and biological factors influencing women's TSD focuses on gender role socialization, sense of competence, technical conditioning, sexism, spatial ability, and risk-taking. The article suggests…

  6. Routledge French technical dictionary

    CERN Document Server

    1994-01-01

    The French-English volume of this highly acclaimed set consists of some 100,000 keywords in both French and English, drawn from the whole range of modern applied science and technical terminology. Covers over 70 subject areas, from engineering and chemistry to packaging, transportation, data processing and much more.

  7. Technical objectives of inspection

    International Nuclear Information System (INIS)

    Sorenson, R.J.; Stewart, K.B.; Schneider, R.A.

    1976-01-01

    The various technical objectives of inspection are discussed in a very general manner. The discussion includes how the inspection function is related to the assumed threat, the various degrees of assurance and reliance on criteria, and the hierarchy of assurance which is obtained from the various types or levels of inspection

  8. NUSC Technical Publications Guide.

    Science.gov (United States)

    1985-05-01

    Facility personnel especially that of A. Castelluzzo, E. Deland, J. Gesel , and E. Szlosek (all of Code 4343). Reviewed and Approved: 14 July 1980 D...their technical content and format. Review and approve the manual outline, the review manuscript, and the final camera - reproducible copy. Conduct in

  9. ITER EDA technical activities

    International Nuclear Information System (INIS)

    Aymar, R.

    1998-01-01

    Six years of technical work under the ITER EDA Agreement have resulted in a design which constitutes a complete description of the ITER device and of its auxiliary systems and facilities. The ITER Council commented that the Final Design Report provides the first comprehensive design of a fusion reactor based on well established physics and technology

  10. Technical basis of safeguards

    International Nuclear Information System (INIS)

    Buechler, C.

    1975-01-01

    Definition of nuclear materials control. Materials accountancy and physical control as technical possibilities. Legal possibilities and levels of responsibility: material holders, national and international authority. Detection vs. prevention. Physical security and containment surveillance. Accountancy: materials balance concept. Materials measurement: inventory taking, flow determination. IAEA safeguards; verification of operator's statement. (HP) [de

  11. Technical memory 1999

    International Nuclear Information System (INIS)

    2000-01-01

    The technical memory 1999 of the Nuclear Regulatory Authority (NRA) of the Argentine Republic, compile the papers published in the subject on radiation protection and nuclear safety, safeguards and physical protection, and presented in congress or meetings of these specialities by personnel of the mentioned institution during 1999

  12. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: LabVIEW Real-Time (F) : 7 - 9.6.2005 (3 jours) LabVIEW Migration 6 to 7: 14.6.2005 (1 day) IT3T/1 - Read your mail and more with Outlook 2003 : 14.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/2 - Creating, managing and using distribution lists with Simba2 : 16.6.2005 (IT Technical Training Tutorial, free of charge) FrontPage 2003 - niveau 2 : 16 & 17.6.2005 (2 jours) Utilisation de fichiers PDF avec ACROBAT 6.0 : 20.6.2005 (1journée) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP : 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003 : 30.6.2005 (IT Technical Training Tutorial, free of charge) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoC...

  13. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    John Ross

    2003-04-30

    The Final Technical Report summarizes research accomplishments and Publications in the period of 5/1/99 to 4/30/03 done on the grant. Extensive progress was made in the period covered by this report in the areas of chemical kinetics of non-linear systems; spatial structures, reaction - diffusion systems, and thermodynamic and stochastic theory of electrochemical and general systems.

  14. Materials Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-08-01

    Roadmap identifying the efforts of the Materials Technical Team (MTT) to focus primarily on reducing the mass of structural systems such as the body and chassis in light-duty vehicles (including passenger cars and light trucks) which enables improved vehicle efficiency regardless of the vehicle size or propulsion system employed.

  15. Technical Writing in Hydrogeology.

    Science.gov (United States)

    Tinker, John R., Jr.

    1986-01-01

    A project for Writing Across the Curriculum at the University of Wisconsin-Eau Claire is described as a method to relate the process of writing to the process of learning hydrology. The project focuses on an actual groundwater contamination case and is designed to improve the technical writing skills of students. (JN)

  16. Review of technical specifications

    International Nuclear Information System (INIS)

    Bedrich, M.; Scholz, D.

    1980-01-01

    The present paper deals with position and function of technical specifications before and during the manufacturing of reactor components, their structure and reasons for specific regulations due to safety philosophy and explains the cooperation of supplier, manufacturer, utilities and supervisory organizations. (RW)

  17. PISA 2009 Technical Report

    Science.gov (United States)

    OECD Publishing (NJ1), 2012

    2012-01-01

    The "PISA 2009 Technical Report" describes the methodology underlying the PISA 2009 survey. It examines additional features related to the implementation of the project at a level of detail that allows researchers to understand and replicate its analyses. The reader will find a wealth of information on the test and sample design,…

  18. PISA 2012 Technical Report

    Science.gov (United States)

    OECD Publishing, 2014

    2014-01-01

    The "PISA 2012 Technical Report" describes the methodology underlying the PISA 2012 survey, which tested 15-year-olds' competencies in mathematics, reading and science and, in some countries, problem solving and financial literacy. It examines the design and implementation of the project at a level of detail that allows researchers to…

  19. New usable technical specifications

    International Nuclear Information System (INIS)

    Webster, S.A.; Tomasi, L.T.; Bernier, R.A.

    1989-01-01

    After 2 yr of preparation, 1988 finally saw the nuclear industry writing operator-oriented technical specifications. This effort is a continuation of previous efforts to develop improved and usable standard technical specifications (STSs), and is being conducted by the four nuclear steam supply system vendor owners' groups under the auspices of the Nuclear Management Resources Council. Each participant is currently preparing a set of improved STSs based on a writer's guide that was developed through a combined industry effort. In May of 1987, a Human Factors Improvements to Technical Specifications (HFITS) task group was formed to prepare a writer's guide for improved, industrywide STSs. This task group was composed of two representatives from each owners' group, one with a human factors background and one with some operations background. Two documents were prepared in 6 months, a human factors report laying the groundwork for the considerations to go into technical specifications and a writer's guide for their preparation. This paper reports on the application of this writer's guide to the writing of improved STS

  20. ITER co-ordinated technical activities

    International Nuclear Information System (INIS)

    2001-01-01

    As agreed upon between the ITER Engineering Design Activities (EDA) Parties 'Co-ordinated Technical Activities' (CTA) means technical activities which are deemed necessary to maintain the integrity of the international project, so as to prepare for the ITER joint implementation. The scope of these activities includes design adaptation to the specific site conditions, safety analysis and licensing preparation that are based on specific site offers, evaluation of cost and construction schedule, preparation of procurement documents and other issues raised by the Parties collectively, whilst assuring the coherence of the ITER project including design control

  1. Electrical Aversion Conditioning with Chronic Alcoholics

    Science.gov (United States)

    Vogler, Roger E.; And Others

    1970-01-01

    Pseudoconditioning (random shock delivery), sham conditioning (no shock), and ward controls (routine hospital treatment) ( were compared with two conditioning groups. Conditioning only (contingent shock) and booster Ss (additional conditioning sessions after release from hospital) were shocked for drinking and reinforced by shock termination for…

  2. Computer-controlled 3-D treatment delivery

    International Nuclear Information System (INIS)

    Fraass, Benedick A.

    1995-01-01

    Purpose/Objective: This course will describe the use of computer-controlled treatment delivery techniques for treatment of patients with sophisticated conformal therapy. In particular, research and implementation issues related to clinical use of computer-controlled conformal radiation therapy (CCRT) techniques will be discussed. The possible/potential advantages of CCRT techniques will be highlighted using results from clinical 3-D planning studies. Materials and Methods: In recent years, 3-D treatment planning has been used to develop and implement 3-D conformal therapy treatment techniques, and studies based on these conformal treatments have begun to show the promise of conformal therapy. This work has been followed by the development of commercially-available multileaf collimator and computer control systems for treatment machines. Using these (and other) CCRT devices, various centers are beginning to clinically use complex computer-controlled treatments. Both research and clinical CCRT treatment techniques will be discussed in this presentation. General concepts and requirements for CCRT will be mentioned. Developmental and clinical experience with CCRT techniques from a number of centers will be utilized. Results: Treatment planning, treatment preparation and treatment delivery must be approached in an integrated fashion in order to clinically implement CCRT treatment techniques, and the entire process will be discussed. Various CCRT treatment methodologies will be reviewed from operational, dosimetric, and technical points of view. The discussion will concentrate on CCRT techniques which are likely to see rather wide dissemination over the next several years, including particularly the use of multileaf collimators (MLC), dynamic and segmental conformal therapy, conformal field shaping, and other related techniques. More advanced CCRT techniques, such as the use of individualized intensity modulation of beams or segments, and the use of computer

  3. Manipulation of the Commodity Futures Market Delivery Process.

    OpenAIRE

    Pirrong, Stephen Craig

    1993-01-01

    An analysis of the futures market delivery 'end game' specifies necessary and sufficient conditions for long and short traders to manipulate futures prices at contract expiration. The empirical and welfare implications of manipulation are derived as well. Manipulation is most likely to occur in markets where economic frictions (such as transportation and transactions costs) make it inefficient to return excessive deliveries to their original owners. These consumption distortions induce price ...

  4. Technical Assessment: Integrated Photonics

    Science.gov (United States)

    2015-10-01

    and resources we routinely demand are predicated on the delivery of high-bandwidth services. At the same time, new computing paradigms such as cloud ...state of the art IPCs onshore. Recommendation 11: Continue to implement policies designed to ensure production integrity of IPC technology. This...operators include both content providers such as Netflix, and Amazon , and neutral providers such as Digital Realty, Equinix, and Rackspace. Cloud operators

  5. Secondary fuel delivery system

    Science.gov (United States)

    Parker, David M.; Cai, Weidong; Garan, Daniel W.; Harris, Arthur J.

    2010-02-23

    A secondary fuel delivery system for delivering a secondary stream of fuel and/or diluent to a secondary combustion zone located in the transition piece of a combustion engine, downstream of the engine primary combustion region is disclosed. The system includes a manifold formed integral to, and surrounding a portion of, the transition piece, a manifold inlet port, and a collection of injection nozzles. A flowsleeve augments fuel/diluent flow velocity and improves the system cooling effectiveness. Passive cooling elements, including effusion cooling holes located within the transition boundary and thermal-stress-dissipating gaps that resist thermal stress accumulation, provide supplemental heat dissipation in key areas. The system delivers a secondary fuel/diluent mixture to a secondary combustion zone located along the length of the transition piece, while reducing the impact of elevated vibration levels found within the transition piece and avoiding the heat dissipation difficulties often associated with traditional vibration reduction methods.

  6. Focus on Delivery

    DEFF Research Database (Denmark)

    Hasman, Kirsten; Barfoed, Anne

    Background: Compared to other Nordic countries, Denmark has a high incidence of anal sphincter injury. Recent studies indicate that a strict focus on prevention of severe perineal trauma has decreased the incidence (1). This has resulted in changed clinical procedures in several Danish labour wards...... (2). It is, however, not clarified which of the multifaceted aspects of preventing perineal injury that might explain the decrease (3). Aims: We hypothesized that the use of structured reflection on a clinical practice by midwives and midwifery students would increase both parts’ knowledge on how...... attended the delivery, facilitated the midwife’s and the student’s structured reflection. Further, the project midwife held daily simulation workshops with midwives and students. Two focus group interviews with students and midwives were conducted and analyzed using content analysis. Results and conclusion...

  7. Chitosan microspheres in novel drug delivery systems.

    Science.gov (United States)

    Mitra, Analava; Dey, Baishakhi

    2011-07-01

    The main aim in the drug therapy of any disease is to attain the desired therapeutic concentration of the drug in plasma or at the site of action and maintain it for the entire duration of treatment. A drug on being used in conventional dosage forms leads to unavoidable fluctuations in the drug concentration leading to under medication or overmedication and increased frequency of dose administration as well as poor patient compliance. To minimize drug degradation and loss, to prevent harmful side effects and to increase drug bioavailability various drug delivery and drug targeting systems are currently under development. Handling the treatment of severe disease conditions has necessitated the development of innovative ideas to modify drug delivery techniques. Drug targeting means delivery of the drug-loaded system to the site of interest. Drug carrier systems include polymers, micelles, microcapsules, liposomes and lipoproteins to name some. Different polymer carriers exert different effects on drug delivery. Synthetic polymers are usually non-biocompatible, non-biodegradable and expensive. Natural polymers such as chitin and chitosan are devoid of such problems. Chitosan comes from the deacetylation of chitin, a natural biopolymer originating from crustacean shells. Chitosan is a biocompatible, biodegradable, and nontoxic natural polymer with excellent film-forming ability. Being of cationic character, chitosan is able to react with polyanions giving rise to polyelectrolyte complexes. Hence chitosan has become a promising natural polymer for the preparation of microspheres/nanospheres and microcapsules. The techniques employed to microencapsulate with chitosan include ionotropic gelation, spray drying, emulsion phase separation, simple and complex coacervation. This review focuses on the preparation, characterization of chitosan microspheres and their role in novel drug delivery systems.

  8. Modified montmorillonite as vector for gene delivery.

    Science.gov (United States)

    Lin, Feng-Huei; Chen, Chia-Hao; Cheng, Winston T K; Kuo, Tzang-Fu

    2006-06-01

    Currently, gene delivery systems can be divided into two parts: viral or non-viral vectors. In general, viral vectors have a higher efficiency on gene delivery. However, they may sometimes provoke mutagenesis and carcinogenesis once re-activating in human body. Lots of non-viral vectors have been developed that tried to solve the problems happened on viral vectors. Unfortunately, most of non-viral vectors showed relatively lower transfection rate. The aim of this study is to develop a non-viral vector for gene delivery system. Montmorillonite (MMT) is one of clay minerals that consist of hydrated aluminum with Si-O tetrahedrons on the bottom of the layer and Al-O(OH)2 octahedrons on the top. The inter-layer space is about 12 A. The room is not enough to accommodate DNA for gene delivery. In the study, the cationic hexadecyltrimethylammonium (HDTMA) will be intercalated into the interlayer of MMT as a layer expander to expand the layer space for DNA accommodation. The optimal condition for the preparation of DNA-HDTMA-MMT is as follows: 1 mg of 1.5CEC HDTMA-MMT was prepared under pH value of 10.7 and with soaking time for 2 h. The DNA molecules can be protected from nuclease degradation, which can be proven by the electrophoresis analysis. DNA was successfully transfected into the nucleus of human dermal fibroblast and expressed enhanced green fluorescent protein (EGFP) gene with green fluorescence emission. The HDTMA-MMT has a great potential as a vector for gene delivery in the future.

  9. Tank Farms Technical Safety Requirements. Volume 1 and 2

    International Nuclear Information System (INIS)

    CASH, R.J.

    2000-01-01

    The Technical Safety Requirements (TSRs) define the acceptable conditions, safe boundaries, basis thereof, and controls to ensure safe operation during authorized activities, for facilities within the scope of the Tank Waste Remediation System (TWRS) Final Safety Analysis Report (FSAR)

  10. CHECKING OF TECHNICAL BRIDGES’ STATE BY PASSIVE VIBRATIONAL DYNAMICS METHODS

    Directory of Open Access Journals (Sweden)

    V. P. Redchenko

    2010-03-01

    Full Text Available In the article the results of studies of the passive vibration test methods and the possibilities of using them for determining and monitoring of technical condition of bridges are presented.

  11. Tank Farms Technical Safety Requirements [VOL 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    CASH, R.J.

    2000-12-28

    The Technical Safety Requirements (TSRs) define the acceptable conditions, safe boundaries, basis thereof, and controls to ensure safe operation during authorized activities, for facilities within the scope of the Tank Waste Remediation System (TWRS) Final Safety Analysis Report (FSAR).

  12. Technical specifications and performance of CANDU fuel

    International Nuclear Information System (INIS)

    Sejnoha, R.

    1997-01-01

    The relations between Technical Specifications and fuel performance are discussed in terms of design limits and margins. The excellent performance record of CANDU reactor fuel demonstrates that the fuel design defined in the Technical Specifications (and with it other components of the procurement cycle, such as fuel manufacturing), satisfy the requirements. New requirements, changing conditions of fuel application and accumulating experience make periodic updates of the Technical Specifications necessary. Under the CANDU Owners Group (COG) Working Party 9, a Work Package has been conducted to support the review of the Specifications and the documentation of the rationales for their requirements. So far, the review has been completed for 4 Specifications: 1 for Zircaloy tubing, and 3 for uranium dioxide powder. It is planned to complete the review of all 11 currently used specifications by 1999. The paper summarizes the results achieved to mid 1997. (author)

  13. Learning from Health Information Exchange Technical Architecture and Implementation in Seven Beacon Communities

    Science.gov (United States)

    McCarthy, Douglas B.; Propp, Karen; Cohen, Alexander; Sabharwal, Raj; Schachter, Abigail A.; Rein, Alison L.

    2014-01-01

    As health care providers adopt and make “meaningful use” of health information technology (health IT), communities and delivery systems must set up the infrastructure to facilitate health information exchange (HIE) between providers and numerous other stakeholders who have a role in supporting health and care. By facilitating better communication and coordination between providers, HIE has the potential to improve clinical decision-making and continuity of care, while reducing unnecessary use of services. When implemented as part of a broader strategy for health care delivery system and payment reform, HIE capability also can enable the use of analytic tools needed for population health management, patient engagement in care, and continuous learning and improvement. The diverse experiences of seven communities that participated in the three-year federal Beacon Community Program offer practical insight into factors influencing the technical architecture of exchange infrastructure and its role in supporting improved care, reduced cost, and a healthier population. The case studies also document challenges faced by the communities, such as significant time and resources required to harmonize variations in the interpretation of data standards. Findings indicate that their progress developing community-based HIE strategies, while driven by local needs and objectives, is also influenced by broader legal, policy, and market conditions. PMID:25848591

  14. Learning from health information exchange technical architecture and implementation in seven beacon communities.

    Science.gov (United States)

    McCarthy, Douglas B; Propp, Karen; Cohen, Alexander; Sabharwal, Raj; Schachter, Abigail A; Rein, Alison L

    2014-01-01

    As health care providers adopt and make "meaningful use" of health information technology (health IT), communities and delivery systems must set up the infrastructure to facilitate health information exchange (HIE) between providers and numerous other stakeholders who have a role in supporting health and care. By facilitating better communication and coordination between providers, HIE has the potential to improve clinical decision-making and continuity of care, while reducing unnecessary use of services. When implemented as part of a broader strategy for health care delivery system and payment reform, HIE capability also can enable the use of analytic tools needed for population health management, patient engagement in care, and continuous learning and improvement. The diverse experiences of seven communities that participated in the three-year federal Beacon Community Program offer practical insight into factors influencing the technical architecture of exchange infrastructure and its role in supporting improved care, reduced cost, and a healthier population. The case studies also document challenges faced by the communities, such as significant time and resources required to harmonize variations in the interpretation of data standards. Findings indicate that their progress developing community-based HIE strategies, while driven by local needs and objectives, is also influenced by broader legal, policy, and market conditions.

  15. Intracranial drug delivery for subarachnoid hemorrhage.

    Science.gov (United States)

    Macdonald, Robert Loch; Leung, Ming; Tice, Tom

    2012-01-01

    Tice and colleagues pioneered site-specific, sustained-release drug delivery to the brain almost 30 years ago. Currently there is one drug approved for use in this manner. Clinical trials in subarachnoid hemorrhage have led to approval of nimodipine for oral and intravenous use, but other drugs, such as clazosentan, hydroxymethylglutaryl CoA reductase inhibitors (statins) and magnesium, have not shown consistent clinical efficacy. We propose that intracranial delivery of drugs such as nimodipine, formulated in sustained-release preparations, are good candidates for improving outcome after subarachnoid hemorrhage because they can be administered to patients that are already undergoing surgery and who have a self-limited condition from which full recovery is possible.

  16. Chitosan magnetic nanoparticles for drug delivery systems.

    Science.gov (United States)

    Assa, Farnaz; Jafarizadeh-Malmiri, Hoda; Ajamein, Hossein; Vaghari, Hamideh; Anarjan, Navideh; Ahmadi, Omid; Berenjian, Aydin

    2017-06-01

    The potential of magnetic nanoparticles (MNPs) in drug delivery systems (DDSs) is mainly related to its magnetic core and surface coating. These coatings can eliminate or minimize their aggregation under physiological conditions. Also, they can provide functional groups for bioconjugation to anticancer drugs and/or targeted ligands. Chitosan, as a derivative of chitin, is an attractive natural biopolymer from renewable resources with the presence of reactive amino and hydroxyl functional groups in its structure. Chitosan nanoparticles (NPs), due to their huge surface to volume ratio as compared to the chitosan in its bulk form, have outstanding physico-chemical, antimicrobial and biological properties. These unique properties make chitosan NPs a promising biopolymer for the application of DDSs. In this review, the current state and challenges for the application magnetic chitosan NPs in drug delivery systems were investigated. The present review also revisits the limitations and commercial impediments to provide insight for future works.

  17. Nano/Micro Formulations for Bacteriophage Delivery.

    Science.gov (United States)

    Cortés, Pilar; Cano-Sarabia, Mary; Colom, Joan; Otero, Jennifer; Maspoch, Daniel; Llagostera, Montserrat

    2018-01-01

    Encapsulation methodologies allow the protection of bacteriophages for overcoming critical environmental conditions. Moreover, they improve the stability and the controlled delivery of bacteriophages which is of great innovative value in bacteriophage therapy. Here, two different encapsulation methodologies of bacteriophages are described using two biocompatible materials: a lipid cationic mixture and a combination of alginate with the antacid CaCO 3 . To perform bacteriophage encapsulation, a purified lysate highly concentrated (around 10 10 -10 11  pfu/mL) is necessary, and to dispose of a specific equipment. Both methodologies have been successfully applied for encapsulating Salmonella bacteriophages with different morphologies. Also, the material employed does not modify the antibacterial action of bacteriophages. Moreover, both technologies can also be adapted to any bacteriophage and possibly to any delivery route for bacteriophage therapy.

  18. Ecological and technical situation of flooded oil wells in Kazakhstan

    International Nuclear Information System (INIS)

    Kuterbekov, K. A.; Kabdrakhimova, G. D.; Nurakhmetov, T. N.; Zhaksigulova, A.; Nukenov, D. N.; Kushkimbaev, B. M.; Nurmukhanbetova, A. K.

    2012-01-01

    The data of ecological and technical condition of flooded and inundated wells in Atyrau and Mangystau regions of the West of Kazakhstan is given in this abstract. There is necessary to elaborate methods for liquidation, individual plans of conservations, to produce isolating and liquidation procedures on wells and to estimate environment effects. Also we will provide for estimation technical condition of conservation oil wells on territory of flooded by Caspian sea. (Authors)

  19. Bioethics for Technical Experts

    Science.gov (United States)

    Asano, Shigetaka

    Along with rapidly expanding applications of life science and technology, technical experts have been implicated more and more often with ethical, social, and legal problems than before. It should be noted that in this background there are scientific and social uncertainty elements which are inevitable during the progress of life science in addition to the historically-established social unreliability to scientists and engineers. In order to solve these problems, therefore, we should establish the social governance with ‘relief’ and ‘reliance’ which enables for both citizens and engineers to share the awareness of the issues, to design social orders and criterions based on hypothetical sense of values for bioethics, to carry out practical use management of each subject carefully, and to improve the sense of values from hypothetical to universal. Concerning these measures, the technical experts can learn many things from the present performance in the medical field.

  20. Sources of technical assistance

    International Nuclear Information System (INIS)

    Laue, H.J.

    1977-01-01

    This paper shows examples of technical assistance programmes within bilateral cooperation agreements between the Federal Republic of Germany and a number of developing countries of very different characteristics and summarizes the possibilities of technical assistance granted by international organizations, such as IAEA, UNDP, etc. A basic requirement for a successful transfer of technology is a high knowledge level of the indigenous scientists and engineers. Therefore, programmes for training and education and for information exchange are presented. Based on these, the means and methods of planning, performance and quality assurance are explained by practical examples and are related to the progress achieved in the use of nuclear energy and in establishing a national industry in the developing countries. (orig.) [de

  1. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The Joint PVSS JCOP Framework: 14 - 18.6.2004 (5 days) EXCEL 2003 - niveau 2 : 17 & 18.6.2004 (2 jours) MAGNE-04 : Magnétisme pour l'électrotechnique : 6 au 8.7.2004 (3 jours) Technical Training Monique Duval - Tel.74924 technical.training@cern.ch

  2. Understanding Socio Technical Modularity

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Kudsk, Anders; Hvam, Lars

    2011-01-01

    Modularity has gained an increasing popularity as a central concept for exploring product structure, process structure, organization structure and supply chain structure. With the offset in system theory the predominant understanding of modularity however faces difficulties in explaining the social...... dimension of modularity like irrational behaviors, cultural differences, learning processes, social organization and institutional influences on modularity. The paper addresses this gab offering a reinterpretation of the modularity concept from a socio-technical perspective in general and Actor Network...... Theory in particular. By formulating modularity from an ANT perspective covering social, material and process aspects, the modularity of a socio-technical system can be understood as an entanglement of product, process, organizational and institutional modularity. The theoretical framework is illustrated...

  3. Independent technical review, handbook

    International Nuclear Information System (INIS)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project

  4. Independent technical review, handbook

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project.

  5. Emerging Frontiers in Drug Delivery.

    Science.gov (United States)

    Tibbitt, Mark W; Dahlman, James E; Langer, Robert

    2016-01-27

    Medicine relies on the use of pharmacologically active agents (drugs) to manage and treat disease. However, drugs are not inherently effective; the benefit of a drug is directly related to the manner by which it is administered or delivered. Drug delivery can affect drug pharmacokinetics, absorption, distribution, metabolism, duration of therapeutic effect, excretion, and toxicity. As new therapeutics (e.g., biologics) are being developed, there is an accompanying need for improved chemistries and materials to deliver them to the target site in the body, at a therapeutic concentration, and for the required period of time. In this Perspective, we provide an historical overview of drug delivery and controlled release followed by highlights of four emerging areas in the field of drug delivery: systemic RNA delivery, drug delivery for localized therapy, oral drug delivery systems, and biologic drug delivery systems. In each case, we present the barriers to effective drug delivery as well as chemical and materials advances that are enabling the field to overcome these hurdles for clinical impact.

  6. Synthetic sustained gene delivery systems.

    Science.gov (United States)

    Agarwal, Ankit; Mallapragada, Surya K

    2008-01-01

    Gene therapy today is hampered by the need of a safe and efficient gene delivery system that can provide a sustained therapeutic effect without cytotoxicity or unwanted immune responses. Bolus gene delivery in solution results in the loss of delivered factors via lymphatic system and may cause undesired effects by the escape of bioactive molecules to distant sites. Controlled gene delivery systems, acting as localized depot of genes, provide an extended sustained release of genes, giving prolonged maintenance of the therapeutic level of encoded proteins. They also limit the DNA degradation in the nuclease rich extra-cellular environment. While attempts have been made to adapt existing controlled drug delivery technologies, more novel approaches are being investigated for controlled gene delivery. DNA encapsulated in nano/micro spheres of polymers have been administered systemically/orally to be taken up by the targeted tissues and provide sustained release once internalized. Alternatively, DNA entrapped in hydrogels or scaffolds have been injected/implanted in tissues/cavities as platforms for gene delivery. The present review examines these different modalities for sustained delivery of viral and non-viral gene-delivery vectors. Design parameters and release mechanisms of different systems made with synthetic or natural polymers are presented along with their prospective applications and opportunities for continuous development.

  7. Technical approach document

    International Nuclear Information System (INIS)

    1989-12-01

    The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs

  8. Technical Leadership Development Program

    Science.gov (United States)

    2010-12-13

    the traditional tenets of leadership and management , systems thinking, understanding SOS issues, and thinking and acting holistically. Our research...international element 2.0 Enterprise Leadership and Management UNCLASSIFIED Contract Number: H98230-08-D-0171 DO 002. TO002, RT 004 Report No...mechanisms for leadership of the overall technical effort, for systems engineering, for requirements, management , and for systems integration. o Develop

  9. Technical issues for WIPP

    International Nuclear Information System (INIS)

    Hunter, T.O.

    1979-01-01

    Emplacement of wastes in the WIPP will include experiments on various waste types which will provide essential data on waste-rock interaction and repository response. These experiments will include evolution of the synergistic effects of both heat production, radiation, and actual waste forms. While these studies will provide essential data on the validity of waste isolation in bedded salt, they will be preceded by a broad-based experimental program which will resolve many of the current technical issues providing not only an assessment of the safety of performing such experiments but also the technical basis for assurance that the appropriate experiments are performed. Data and predictive modeling techniques, which are currently available, can bound the consequences associated with these technical issues. Predictions of the impact on public safety based on these analyses indicate that safe waste disposal in WIPP salt beds is achievable; however, a major use of WIPP will be to conduct realistic experiments with HLW forms to address some of the unresolved details of these waste/salt interactions

  10. Technical training - Places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department Electronic Design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 4 places Electrostatique / Protection ESD 28-Sep-12 to 28-Sep-12 3 hours French 25 places Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 14 places Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 9 places LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places LabVIEW for Experts 24-Sep-12 to 28-Sep-12 5 days English 6 places LabVIEW for beginners 15-Oct-12 to 17-...

  11. Technical Assistance Needs Assessments (TANAs)

    Science.gov (United States)

    The Technical Assistance Needs Assessment (TANA) is a process to identify whether a community requires additional support from EPA in order to understand technical information and have meaningful participation in the Superfund decision-making process.

  12. El Salvador - Formal Technical Education

    Data.gov (United States)

    Millennium Challenge Corporation — With a budget of nearly $20 million, the Formal Technical Education Sub-Activity was designed to strengthen technical and vocational educational institutions in the...

  13. Heart Conditions and Pregnancy: Know the Risks

    Science.gov (United States)

    ... function during the delivery. Your doctor might recommend scheduling a date to induce labor under controlled conditions ... of Privacy Practices Notice of Nondiscrimination Manage Cookies Advertising Mayo Clinic is a not-for-profit organization ...

  14. Swallowable smart pills for local drug delivery: present status and future perspectives.

    Science.gov (United States)

    Goffredo, Rosa; Accoto, Dino; Guglielmelli, Eugenio

    2015-01-01

    Smart pills were originally developed for diagnosis; however, they are increasingly being applied to therapy - more specifically drug delivery. In addition to smart drug delivery systems, current research is also looking into localization systems for reaching the target areas, novel locomotion mechanisms and positioning systems. Focusing on the major application fields of such devices, this article reviews smart pills developed for local drug delivery. The review begins with the analysis of the medical needs and socio-economic benefits associated with the use of such devices and moves onto the discussion of the main implemented technological solutions with special attention given to locomotion systems, drug delivery systems and power supply. Finally, desired technical features of a fully autonomous robotic capsule for local drug delivery are defined and future research trends are highlighted.

  15. The Agency's technical co-operation activities in 1992

    International Nuclear Information System (INIS)

    1993-08-01

    This report on the International Atomic Energy Agency's Technical Co-operation Activities in 1992 contains an overview of the general issues involved, including both in-house and external developments, resources and delivery, and evaluation of programs; an overview by field of activity and by division within the Agency; an overview by geographic area, distinguishing (i) Africa, (ii) Asia and the Pacific, (iii) Latin America, (iv) and the Middle East and Europe; an overview by component (i.e., experts, equipment, fellowships, training courses, sub-contracts and miscellaneous); and an overview by fund technical assistance and co-operation fund, extrabudgetary resources, United Nations Development Program (UNDP), assistance in kind. It also contains a profile on technical co-operation activities in Latin America. Projects concluded during 1992 are listed together with a description of their achievements. It concludes with implementation summaries. 10 figs, 9 tabs

  16. Assessing Students' Technical Skill Attainment

    Science.gov (United States)

    Jorgensen, Haley

    2010-01-01

    The Wisconsin Technical College System (WTCS) is working to comply with the Carl D. Perkins Career and Technical Education Improvement Act of 2006 (Perkins) to ensure that its graduates have mastered the technical skills needed by business and industry. The legislation requires that each state identify and approve program assessment strategies…

  17. Modernizing Electricity Delivery

    Science.gov (United States)

    Explains how modern grid, or smart grid, investments can enable grid operators to respond faster to changes in grid conditions and allow for two-way communication between utilities and electricity end-users.

  18. Recent Advances and Perspectives in Liposomes for Cutaneous Drug Delivery.

    Science.gov (United States)

    Carita, Amanda C; Eloy, Josimar O; Chorilli, Marlus; Lee, Robert J; Leonardi, Gislaine Ricci

    2018-02-13

    The cutaneous route is attractive for the delivery of drugs in the treatment of a wide variety of diseases. However the stratum corneum (SC) is an effective barrier that hampers skin penetration. Within this context, liposomes emerge as a potential carrier for improving topical delivery of therapeutic agents. In this review, we aimed to discuss key aspects for the topical delivery by drug-loaded liposomes. Phospholipid type and phase transition temperature have been shown to affect liposomal topical delivery. The effect of surface charge is subject to considerable variation depending on drug and composition. In addition, modified vesicles with the presence of components for permeation enhancement, such as surfactants and solvents, have been shown to have a considerable effect. These liposomes include: Transfersomes, Niosomes, Ethosomes, Transethosomes, Invasomes, coated liposomes, penetration enhancer containing vesicles (PEVs), fatty acids vesicles, Archaeosomes and Marinosomes. Furthermore, adding polymeric coating onto liposome surface could influence cutaneous delivery. Mechanisms of delivery include intact vesicular skin penetration, free drug diffusion, permeation enhancement, vesicle adsorption to and/or fusion with the SC, trans-appendageal penetration, among others. Finally, several skin conditions, including acne, melasma, skin aging, fungal infections and skin cancer, have benefited from liposomal topical delivery of drugs, with promising in vitro and in vivo results. However, despite the existence of some clinical trials, more studies are needed to be conducted in order to explore the potential of liposomes in the dermatological field. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  19. Electronic Nicotine Delivery Systems.

    Science.gov (United States)

    Walley, Susan C; Jenssen, Brian P

    2015-11-01

    Electronic nicotine delivery systems (ENDS) are rapidly growing in popularity among youth. ENDS are handheld devices that produce an aerosolized mixture from a solution typically containing concentrated nicotine, flavoring chemicals, and propylene glycol to be inhaled by the user. ENDS are marketed under a variety of names, most commonly electronic cigarettes and e-cigarettes. In 2014, more youth reported using ENDS than any other tobacco product. ENDS pose health risks to both users and nonusers. Nicotine, the major psychoactive ingredient in ENDS solutions, is both highly addictive and toxic. In addition to nicotine, other toxicants, carcinogens, and metal particles have been detected in solutions and aerosols of ENDS. Nonusers are involuntarily exposed to the emissions of these devices with secondhand and thirdhand aerosol. The concentrated and often flavored nicotine in ENDS solutions poses a poisoning risk for young children. Reports of acute nicotine toxicity from US poison control centers have been increasing, with at least 1 child death reported from unintentional exposure to a nicotine-containing ENDS solution. With flavors, design, and marketing that appeal to youth, ENDS threaten to renormalize and glamorize nicotine and tobacco product use. There is a critical need for ENDS regulation, legislative action, and counter promotion to protect youth. ENDS have the potential to addict a new generation of youth to nicotine and reverse more than 50 years of progress in tobacco control. Copyright © 2015 by the American Academy of Pediatrics.

  20. Technical Assessment of Cryo-Compressed Hydrogen Storage Tank Systems for Automotive Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ahluwalia, Rajesh [Argonne National Lab. (ANL), Argonne, IL (United States); Hua, T. Q. [Argonne National Lab. (ANL), Argonne, IL (United States); Peng, J. -K. [Argonne National Lab. (ANL), Argonne, IL (United States); Lasher, S. [TIAX LLC, Lexington, MA (United States); McKenney, Kurtis [TIAX LLC, Lexington, MA (United States); Sinha, J. [TIAX LLC, Lexington, MA (United States)

    2009-12-01

    Technical report describing DOE's second assessment report on a third generation (Gen3) system capable of storing hydrogen at cryogenic temperatures within a pressure vessel on-board a vehicle. The report includes an overview of technical progress to date, including the potential to meet DOE onboard storage targets, as well as independent reviews of system cost and energy analyses of the technology paired with delivery costs.

  1. The Interactive Electronic Technical Manual: Requirements, Current Status, and Implementation. Strategy Considerations.

    Science.gov (United States)

    1991-07-01

    authoring systems. Concurrently, great strides in computer-aided design and computer-aided maintenance have contributed to this capability. 12 Junod ...J.; William A. Nugent; and L. John Junod . Plan for the Navy/Air Force Test of the Interactive Electronic Technical Manual (IETM) at Cecil Field...AFHRL Logistics and Human Factors Division, WPAFB. Aug 1990. 12. Junod , John L. PY90 Interactive Electronic Technical Manual (IETM) Portable Delivery

  2. Economic conditions of technical changes in world civil air transport

    Directory of Open Access Journals (Sweden)

    Joanna HAWLENA

    2008-01-01

    Full Text Available The world economic environment of the turn of the century produced many new challenges to civil aviation in expectation of a continued growth in the transportation of passengers and cargo. To meet this growing demand, it will be necessary to increase the fleet and to modernise infrastructure – a process hampered by finances and capacity constraints.Such constraints are especially pressing with regard to the acquisition of new types of large aircraft such as the Airbus A380 and the Boeing 787 and 747-8. Future dominance of the market is, however, difficult to predict, as this will be the outcome of a combination of uncertain parameters.

  3. Research concepts to reduce CO2 emissions at technical conditions

    International Nuclear Information System (INIS)

    Geigle, K.P.; Lammel, O.; Kutne, P.; Schutz, H.; Luckerath, R.; Aigner, M.

    2009-01-01

    Carbon dioxide (CO 2 ) emissions are thought to contribute to climate change and therefore, there is a significant motivation for current gas turbine burner development to reduce those emissions. In order to support burner development, the German Aerospace Center (DLR) utilizes high pressure testing in combination with optical diagnostics enabled by good optical access and numerical simulation. This paper discussed 3 primary activities on CO 2 reduction that have been accomplished recently, notably the simulation of burner development based on the flameless oxidation concept, characterization of syngas combustion behaviour and studying parameters influencing oxyfuel combustion. Enhanced FLOX burner development and flameless oxidation were illustrated and an experimental realization of DLR FLOX burner V1 for operation up to 30 bars was discussed. Several experiments were illustrated and outlined. Computational fluid dynamics and other simulation models were presented. It was concluded that optical diagnostics applicable to high pressure combustion and numerical simulation proved to be extremely helpful for design optimization. 14 refs., 9 figs.

  4. Towards technical interoperability in telemedicine.

    Energy Technology Data Exchange (ETDEWEB)

    Craft, Richard Layne, II

    2004-05-01

    For telemedicine to realize the vision of anywhere, anytime access to care, the question of how to create a fully interoperable technical infrastructure must be addressed. After briefly discussing how 'technical interoperability' compares with other types of interoperability being addressed in the telemedicine community today, this paper describes reasons for pursuing technical interoperability, presents a proposed framework for realizing technical interoperability, identifies key issues that will need to be addressed if technical interoperability is to be achieved, and suggests a course of action that the telemedicine community might follow to accomplish this goal.

  5. Challenges and opportunities in dermal/transdermal delivery

    Science.gov (United States)

    Paudel, Kalpana S; Milewski, Mikolaj; Swadley, Courtney L; Brogden, Nicole K; Ghosh, Priyanka; Stinchcomb, Audra L

    2010-01-01

    Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin irritation would widen the transdermal market for hydrophilic compounds, macromolecules and conventional drugs for new therapeutic indications. As evident from the ongoing clinical trials of a wide variety of drugs for various clinical conditions, there is a great future for transdermal delivery of drugs. PMID:21132122

  6. MODELING OF TARGETED DRUG DELIVERY PART II. MULTIPLE DRUG ADMINISTRATION

    Directory of Open Access Journals (Sweden)

    A. V. Zaborovskiy

    2017-01-01

    Full Text Available In oncology practice, despite significant advances in early cancer detection, surgery, radiotherapy, laser therapy, targeted therapy, etc., chemotherapy is unlikely to lose its relevance in the near future. In this context, the development of new antitumor agents is one of the most important problems of cancer research. In spite of the importance of searching for new compounds with antitumor activity, the possibilities of the “old” agents have not been fully exhausted. Targeted delivery of antitumor agents can give them a “second life”. When developing new targeted drugs and their further introduction into clinical practice, the change in their pharmacodynamics and pharmacokinetics plays a special role. The paper describes a pharmacokinetic model of the targeted drug delivery. The conditions under which it is meaningful to search for a delivery vehicle for the active substance were described. Primary screening of antitumor agents was undertaken to modify them for the targeted delivery based on underlying assumptions of the model.

  7. Quality correction factors of composite IMRT beam deliveries: Theoretical considerations

    International Nuclear Information System (INIS)

    Bouchard, Hugo

    2012-01-01

    Purpose: In the scope of intensity modulated radiation therapy (IMRT) dosimetry using ionization chambers, quality correction factors of plan-class-specific reference (PCSR) fields are theoretically investigated. The symmetry of the problem is studied to provide recommendable criteria for composite beam deliveries where correction factors are minimal and also to establish a theoretical limit for PCSR delivery k Q factors. Methods: The concept of virtual symmetric collapsed (VSC) beam, being associated to a given modulated composite delivery, is defined in the scope of this investigation. Under symmetrical measurement conditions, any composite delivery has the property of having a k Q factor identical to its associated VSC beam. Using this concept of VSC, a fundamental property of IMRT k Q factors is demonstrated in the form of a theorem. The sensitivity to the conditions required by the theorem is thoroughly examined. Results: The theorem states that if a composite modulated beam delivery produces a uniform dose distribution in a volume V cyl which is symmetric with the cylindrical delivery and all beams fulfills two conditions in V cyl : (1) the dose modulation function is unchanged along the beam axis, and (2) the dose gradient in the beam direction is constant for a given lateral position; then its associated VSC beam produces no lateral dose gradient in V cyl , no matter what beam modulation or gantry angles are being used. The examination of the conditions required by the theorem lead to the following results. The effect of the depth-dose gradient not being perfectly constant with depth on the VSC beam lateral dose gradient is found negligible. The effect of the dose modulation function being degraded with depth on the VSC beam lateral dose gradient is found to be only related to scatter and beam hardening, as the theorem holds also for diverging beams. Conclusions: The use of the symmetry of the problem in the present paper leads to a valuable theorem showing

  8. 48 CFR 2452.237-73 - Conduct of Work and Technical Guidance.

    Science.gov (United States)

    2010-10-01

    ... conditions of the contract. (c) The GTR will issue technical guidance in writing or, if issued orally, he/she... Technical Guidance. 2452.237-73 Section 2452.237-73 Federal Acquisition Regulations System DEPARTMENT OF... Provisions and Clauses 2452.237-73 Conduct of Work and Technical Guidance. As prescribed in 2437.110(d...

  9. Methodology for technical risk assessment

    International Nuclear Information System (INIS)

    Waganer, L.M.; Zuckerman, D.S.

    1983-01-01

    A methodology has been developed for and applied to the assessment of the technical risks associated with an evolving technology. This methodology, originally developed for fusion by K. W. Billman and F. R. Scott at EPRI, has been applied to assess the technical risk of a fuel system for a fusion reactor. Technical risk is defined as the risk that a particular technology or component which is currently under development will not achieve a set of required technical specifications (i.e. probability of failure). The individual steps in the technical risk assessment are summarized. The first step in this methodology is to clearly and completely quantify the technical requirements for the particular system being examined. The next step is to identify and define subsystems and various options which appear capable of achieving the required technical performance. The subsystem options are then characterized regarding subsystem functions, interface requirements with the subsystems and systems, important components, developmental obstacles and technical limitations. Key technical subsystem performance parameters are identified which directly or indirectly relate to the system technical specifications. Past, existing and future technical performance data from subsystem experts are obtained by using a Bayesian Interrogation technique. The input data is solicited in the form of probability functions. Thus the output performance of the system is expressed as probability functions

  10. Ceramic drug-delivery devices.

    Science.gov (United States)

    Lasserre, A; Bajpai, P K

    1998-01-01

    A variety of ceramics and delivery systems have been used to deliver chemicals, biologicals, and drugs at various rates for desired periods of time from different sites of implantation. In vitro and in vivo studies have shown that ceramics can successfully be used as drug-delivery devices. Matrices, inserts, reservoirs, cements, and particles have been used to deliver a large variety of therapeutic agents such as antibiotics, anticancer drugs, anticoagulants, analgesics, growth factors, hormones, steroids, and vaccines. In this article, the advantages and disadvantages of conventional drug-delivery systems and the different approaches used to deliver chemical and biological agents by means of ceramic systems will be reviewed.

  11. Argentina technical report

    International Nuclear Information System (INIS)

    2002-01-01

    At present, the Production Cyclotron Facility, installed at the Ezeiza Atomic Centre, is used for Tl-201 production; F-18 and I-123 production will be incorporated during this year. Concerning I-123 production, a system for irradiation of gaseous target has been developed in the frame of the IAEA Technical Assistance Project (ARG4085). The iodine production system delivers an ultra pure radioisotope via nuclear reactions: 124 Xe (p,2n) 123 Cs → 123 Xe → 123 I and 124 Xe (p,pn) 123 Xe → 123 I. This report describes the target and irradiation chamber design, the radiochemical purification process

  12. Technical Report 2000

    International Nuclear Information System (INIS)

    2001-01-01

    The technical memory 2000 of the Nuclear Regulatory Authority (NRA) of the Argentine Republic, compile the papers published in the subject on radiation protection and nuclear safety, safeguards and physical protection, and presented in congress or meetings of these specialities by personnel of the mentioned institution during 2000. In this edition the documents are presented on: Nuclear safety; Radiobiology; Occupational doses; Radiochemical; Environmental studies; Emergency plans; Radiation accidents; and International safeguards. Some of them are realized by agreements between the Nuclear Regulatory Authority of Argentina, universities and other national and international organizations

  13. HPCG Benchmark Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, Michael Allen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dongarra, Jack [Univ. of Tennessee, Knoxville, TN (United States); Luszczek, Piotr [Univ. of Tennessee, Knoxville, TN (United States)

    2013-10-01

    The High Performance Conjugate Gradient (HPCG) benchmark [cite SNL, UTK reports] is a tool for ranking computer systems based on a simple additive Schwarz, symmetric Gauss-Seidel preconditioned conjugate gradient solver. HPCG is similar to the High Performance Linpack (HPL), or Top 500, benchmark [1] in its purpose, but HPCG is intended to better represent how today’s applications perform. In this paper we describe the technical details of HPCG: how it is designed and implemented, what code transformations are permitted and how to interpret and report results.

  14. Technical bid evaluation

    International Nuclear Information System (INIS)

    Bruchhausen, E. v.

    1975-01-01

    It is shown which kind of problems arise for the owners of the project and what is the recommendable method of approach. A detailed description of the necessary working team, information in delegation of work and tasks of procedure, criteria of valuation and classification method. Examples of schemes are shown which are the basis of the technical bid evaluation: tables 'data of system/component' and 'scope of supply'. The procedure of normalization of the bids and of specifying the owners supplies are explained. The content of the final report is described. (HP) [de

  15. RADTRAN 6 Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Neuhauser, Karen Sieglinde [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Heames, Terence John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); O' Donnell, Brandon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dennis, Matthew L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  16. RADTRAN 6 technical manual.

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F.; Neuhauser, Karen Sieglinde; Heames, Terence John; O' Donnell, Brandon M.; Dennis, Matthew L.

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  17. Technics and ethics

    International Nuclear Information System (INIS)

    Budnick, D.; Gemmel, F.

    1981-01-01

    Questions about the sense of life and the responsibility of technology are ethical questions. Young people in our neighbourhood who, compared to some time ago, see, hear and read much more of the world, deal with them increasingly. However, the permanent stream of information does not at all facilitate orientation but prevents many people from gaining some clearness about their own point of view. In asking the questions: where are we today. How can we get on. How can we start. The relation between ethics and technics is discussed under various aspects. (orig./HSCH) [de

  18. Plasmon resonant liposomes for controlled drug delivery

    Science.gov (United States)

    Knights-Mitchell, Shellie S.; Romanowski, Marek

    2015-03-01

    Nanotechnology use in drug delivery promotes a reduction in systemic toxicity, improved pharmacokinetics, and better drug bioavailability. Liposomes continue to be extensively researched as drug delivery systems (DDS) with formulations such as Doxil® and Ambisome® approved by FDA and successfully marketed in the United States. However, the limited ability to precisely control release of active ingredients from these vesicles continues to challenge the broad implementation of this technology. Moreover, the full potential of the carrier to sequester drugs until it can reach its intended target has yet to be realized. Here, we describe a liposomal DDS that releases therapeutic doses of an anticancer drug in response to external stimulus. Earlier, we introduced degradable plasmon resonant liposomes. These constructs, obtained by reducing gold on the liposome surface, facilitate spatial and temporal release of drugs upon laser light illumination that ultimately induces an increase in temperature. In this work, plasmon resonant liposomes have been developed to stably encapsulate and retain doxorubicin at physiological conditions represented by isotonic saline at 37o C and pH 7.4. Subsequently, they are stimulated to release contents either by a 5o C increase in temperature or by laser illumination (760 nm and 88 mW/cm2 power density). Successful development of degradable plasmon resonant liposomes responsive to near-infrared light or moderate hyperthermia can provide a new delivery method for multiple lipophilic and hydrophilic drugs with pharmacokinetic profiles that limit clinical utility.

  19. Fluoride loaded polymeric nanoparticles for dental delivery.

    Science.gov (United States)

    Nguyen, Sanko; Escudero, Carlos; Sediqi, Nadia; Smistad, Gro; Hiorth, Marianne

    2017-06-15

    The overall aim of the present paper was to develop fluoride loaded nanoparticles based on the biopolymers chitosan, pectin, and alginate, for use in dental delivery. First, the preparation of nanoparticles in the presence of sodium fluoride (NaF) as the active ingredient by ionic gelation was investigated followed by an evaluation of their drug entrapment and release properties. Chitosan formed stable, spherical, and monodisperse nanoparticles in the presence of NaF and tripolyphoshate as the crosslinker, whereas alginate and pectin were not able to form any definite nanostructures in similar conditions. The fluoride loading capacity was found to be 33-113ppm, and the entrapment efficiency 3.6-6.2% for chitosan nanoparticles prepared in 0.2-0.4% (w/w) NaF, respectively. A steady increase in the fluoride release was observed for chitosan nanoparticles prepared in 0.2% NaF both in pH5 and 7 until it reached a maximum at time point 4h and maintained at this level for at least 24h. Similar profiles were observed for formulations prepared in 0.4% NaF; however the fluoride was released at a higher level at pH5. The low concentration, but continuous delivery of fluoride from the chitosan nanoparticles, with possible expedited release in acidic environment, makes these formulations highly promising as dental delivery systems in the protection against caries development. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Methods and metrics challenges of delivery-system research

    Directory of Open Access Journals (Sweden)

    Alexander Jeffrey A

    2012-03-01

    Full Text Available Abstract Background Many delivery-system interventions are fundamentally about change in social systems (both planned and unplanned. This systems perspective raises a number of methodological challenges for studying the effects of delivery-system change--particularly for answering questions related to whether the change will work under different conditions and how the change is integrated (or not into the operating context of the delivery system. Methods The purpose of this paper is to describe the methodological and measurement challenges posed by five key issues in delivery-system research: (1 modeling intervention context; (2 measuring readiness for change; (3 assessing intervention fidelity and sustainability; (4 assessing complex, multicomponent interventions; and (5 incorporating time in delivery-system models to discuss recommendations for addressing these issues. For each issue, we provide recommendations for how research may be designed and implemented to overcome these challenges. Results and conclusions We suggest that a more refined understanding of the mechanisms underlying delivery-system interventions (treatment theory and the ways in which outcomes for different classes of individuals change over time are fundamental starting points for capturing the heterogeneity in samples of individuals exposed to delivery-system interventions. To support the research recommendations outlined in this paper and to advance understanding of the "why" and "how" questions of delivery-system change and their effects, funding agencies should consider supporting studies with larger organizational sample sizes; longer duration; and nontraditional, mixed-methods designs. A version of this paper was prepared under contract with the Agency for Healthcare Research and Quality (AHRQ, US Department of Health and Human Services for presentation and discussion at a meeting on "The Challenge and Promise of Delivery System Research," held in Sterling, VA, on

  1. Extracorporeal photopheresis: Review of technical aspects.

    Science.gov (United States)

    Arora, Satyam; Setia, Rasika

    2017-01-01

    Extracorporeal photochemotherapy (ECP) is considered as an immune modulating therapy majorly targeting the T cells of the Immune system. ECP induces an anti-inflammatory condition with tolerogenic responses without inducing a global immunosuppression state which is a typical feature of other therapeutic options such as steroids. Clinical indication of ECP has grown over time since its initial applications. Our review discusses the technical aspects of the concept of photopheresis with the available methods for its clinical applications.

  2. Advances in the Applications of Polyhydroxyalkanoate Nanoparticles for Novel Drug Delivery System

    Directory of Open Access Journals (Sweden)

    Anupama Shrivastav

    2013-01-01

    Full Text Available Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal in designing drug delivery systems. Over the past few decades, there has been considerable interest in developing biodegradable drug carriers as effective drug delivery systems. Polymeric materials from natural sources play an important role in controlled release of drug at a particular site. Polyhydroxyalkanoates, due to their origin from natural sources, are given attention as candidates for drug delivery materials. Biodegradable and biocompatible polyhydroxyalkanoates are linear polyesters produced by microorganisms under unbalanced growth conditions, which have emerged as potential polymers for use as biomedical materials for drug delivery due to their unique physiochemical and mechanical properties. This review summarizes many of the key findings in the applications of polyhydroxyalkanoates and polyhydroxyalkanoate nanoparticles for drug delivery system.

  3. Desarrollo y aplicación del diagnóstico y pronóstico técnico al mantenimiento de los sistemas centralizados de aire acondicionado. // Develop and application of diagnosis and technical prediction to maintenance of centralized air conditioned systems.

    Directory of Open Access Journals (Sweden)

    J. L. Sánchez Ávila

    2001-10-01

    Full Text Available Se expone la aplicación del mantenimiento por diagnóstico y pronóstico técnico al sistema centralizado de aireacondicionado con recuperación del calor del hotel LTI Bella Costa; como solución a los graves problemas a que seenfrenta la dirección de servicios técnicos de las instalaciones turísticas para realizar un mantenimiento con calidad y a unmenor costo. El desarrollo de un plan experimental, en las instalaciones del hotel, permitió obtener las curvas que expresanel comportamiento de la degradación de estos sistemas en el tiempo, así como determinar el momento más oportuno para larealización del mantenimiento.La aplicación de esta investigación permitió la implementación de un mantenimiento menoscostoso y de más calidad, aumentando la rentabilidad de la labor del mantenimiento, y lo que es decisivo en este tipo deinstalación: la seguridad en la explotación como garantía de un servicio sin fallas.Palabras claves: Mantenimiento, refrigeración, predictivo, diagnóstico, pronóstico.___________________________________________________________________Abstract:The application of maintenance by diagnosis and technical prediction to centralized system of conditioned air withrecovery of heat is exposed; as solution to the serious problems faces technical services of tourist facilities to carry outmaintenance with quality and smaller cost. The development of an experimental plan, in hotel facilities, allowed to obtaincurves that express the behavior of degradation of these systems in time, as well as to determine the most opportunemoment for the maintenance realization. Application of this investigation allowed the implementation of a less expensivemaintenance with more quality, increasing the profitability of maintenance work, and what is decisive in this type ofinstallation,: the security in the exploitation like guarantee of a service without flaws.Key words. Maintenance, refrigeration, prediction, diagnosis, air conditioned.

  4. Analysis of Waste Leak and Toxic Chemical Release Accidents from Waste Feed Delivery (WFD) Diluent System

    Energy Technology Data Exchange (ETDEWEB)

    WILLIAMS, J.C.

    2000-09-15

    Radiological and toxicological consequences are calculated for 4 postulated accidents involving the Waste Feed Delivery (WFD) diluent addition systems. Consequences for the onsite and offsite receptor are calculated. This analysis contains technical information used to determine the accident consequences for the River Protection Project (RPP) Final Safety Analysis Report (FSAR).

  5. Analysis of Waste Leak and Toxic Chemical Release Accidents from Waste Feed Delivery (WFD) Diluent System

    International Nuclear Information System (INIS)

    WILLIAMS, J.C.

    2000-01-01

    Radiological and toxicological consequences are calculated for 4 postulated accidents involving the Waste Feed Delivery (WFD) diluent addition systems. Consequences for the onsite and offsite receptor are calculated. This analysis contains technical information used to determine the accident consequences for the River Protection Project (RPP) Final Safety Analysis Report (FSAR)

  6. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002: Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW hands-on (E):...

  7. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: LabVIEW base 1 : 25 - 27.2.2004(3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) LabVIEW hands-on (E) : 16.3.2004 (afternoon) LabVIEW Basics 1 : 22 - 24.3.2004 ...

  8. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study for Microsoft applications :12.2.2004 (morning) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) CLEAN-2002 ...

  9. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Pa...

  10. Technical training: places available

    CERN Multimedia

    HR Department

    2007-01-01

    CERN Technical Training: Open Courses (April - June 2007) The following course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2007:   AutoCAD 2006 - niveau 1 (course in French): 25.4.- 26.4.2007 & 2.5. - 3.5.2007 (4 days in 2 modules, 5 places available) AutoCAD 2006 - niveau 1 (course in French): 27.6.- 28.6.2007 & 3.7. - 4.7.2007 (4 days in 2 modules, 5 places available) AutoCAD Mechanical 2006 (course in French) 21.6.-22.6.2007 (2 days, 8 places available) * NEW COURSE* Automate de securite S7 (course in French) 14.5.-16.5.2007 (3 days, 4 places available) * NEW COURSE* Automate de securite S7 (course in French): 9.5.-11.5.2007 (3 days, 4 places available) JCOP - Joint PVSS-JCOP Frameswork (course in English): 21.5.-25.5.2007 (5 days, 12 places available) JCOP - Finite State Machines in the JCOP Frameswork (course in English): 12.6.-14.6.2007 (3 days, 12 places available) LabVIEW Basics 1 (in English): 2.-4.5.2007 (3 days, 7 places ...

  11. TECHNICAL TRAINING SEMINAR

    CERN Multimedia

    Davide Vitè

    2002-01-01

    Wednesday 6 March TECHNICAL TRAINING SEMINAR from 9:30 to 16:45 - IT Amphitheatre - bldg. 31.3.004 Analog Devices DSP Day Thorsten Kistler (Application Engineer), Steffen Boerner (Product Specialist) / ANALOG DEVICES Munich Trying to meet your design challenges, Analog Devices compiles application information and offers chipsets, software, reference designs and mixed-signal, application specific DSPs, for a range of real-time signal processing applications. This seminar will present the latest 16bit fixed-point and 32bit floating-point DSPs (roadmaps; internal architectures, blocks, features benchmarks), with their software, development kits and emulators: Fixed-Point DSP-Family, ADSP-218x and ADSP-219x Blackfin DSP SHARC-Family, 2106x and 2116x TigerSHARC Industrial Contact: François Caloz, Sasco-Spoerle GmbH Language: English Free seminar, no registration Organiser: Davide Vitè / HR-TD / 75141 Davide.Vite@cern.ch Please read the full information on the Technical Training Seminars...

  12. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW...

  13. Technical Training: Places available**

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The JAVA Programming Language Level 1 : 9 & 10.1.2004 (2 days) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 ( 6 X 4-hour sessions) LabVIEW hands-on (E) 16.3...

  14. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Project Planning with MS-Project :6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1: 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1 : 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL : 2 - 4.6.2...

  15. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 28.6 - 1.7.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo... Work with long documents : 6.7.2005 (afternoon) ACCES...

  16. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Joint PVSS JCOP Framework: 8 - 12.8.2005 (5 days) FrontPage 2003 - niveau 1 : 1 - 2.9.2005 (2 jours) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.9.2005 (1 jour) LabVIEW Basics 1 : 5 - 7.9.2005 (3 days, dates to be confirmed) Introduction à Windows XP au CERN : 12.9.2005 (1 demi-journée) FrontPage 2003 - niveau 2 : 15 - 16.9.2005 (2 jours) AutoCAD 2005 - niveau 1 : 22, 23, 28, 29.9.2005 (4 jours) MAGNE-05 - Magnétisme pour l'électrotechnique : 27 - 29.9.2005 (3 jours) LabVIEW Application Development (Intermediate I): 5 - 7.12.2005 (3 days) LabVIEW Advanced Programming (Intermediate 2): 8 - 9.12.2005 (2 days) ENSEIGNEMENT TECHNIQUE TECHNICAL TRAINING Monique Duval 74924 technical.training@cern.ch

  17. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo (4 mornings) EXCEL 2003 (Short Course I) - HowTo... Work ...

  18. Technical Training: Places Available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Oracle 9i: SQL: 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9i : New f...

  19. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) VisualEliteHDL : 25 & 26.5.2004 (2 days) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9...

  20. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 1.4.2004 (morning) FrontPage XP - niveau 1 : 5 & 6.4.2004 (2 jours) AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 day...

  1. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 - 30.4.2004 (5 days) Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Pla...

  2. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Planning with MS-Project : 6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 10 - 12.5.2004 (3...

  3. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 days) LabVIEW Hands-on : 20.4.2004 (half-day, p.m.) FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 -...

  4. TECHNICAL TRAINING: Places available**

    CERN Multimedia

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Hands-on Introduction to Python Programming : 12 - 14.11.03(3 days) ACCESS 2000 - niveau 1 : 13 & 14.11.03 (2 jours) C++ for Particle Physicists : 17 - 21.11.03 (6 X 3-hour lectures) Programmation automate Schneider TSX Premium - niveau 2 : 18 - 21.11.03 (4 jours) Project Planning with MS-Project  (free of charg...

  5. TECHNICAL TRAINING: Places available**

    CERN Multimedia

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval Tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The EDMS-MTF in practice (free of charge) : 28 -  30.10.03 (6 half-day sessions) AutoCAD 2002 – Level 1 : 3, 4, 12, 13.11.03 (4 days) LabVIEW TestStand ver. 3 : 4 & 5.11.03 (2 days) Introduction to PSpice : 4.11.03 p.m. (half-day) Hands-on Introduction to Python Programming : 12 – 14.11.03 (3 days) ACCESS ...

  6. Contributing Indications to the Rising Cesarean Delivery Rate

    Science.gov (United States)

    BARBER, Emma L.; LUNDSBERG, Lisbet; BELANGER, Kathleen; PETTKER, Christian M.; FUNAI, Edmund F.; ILLUZZI, Jessica L.

    2013-01-01

    OBJECTIVE To examine physician-documented indications for cesarean delivery in order to investigate the specific indications contributing to this increase. METHODS We analyzed rates of primary and repeat cesarean delivery, including indications for the procedure, among 32,443 live births at a major academic hospital between 2003–2009. Time trends for each indication were modeled to estimate the absolute and cumulative annualized relative risk of cesarean by indication over time and the relative contribution of each indication to the overall increase in primary cesarean delivery rate. RESULTS The cesarean delivery rate increased from 26% to 36.5% between 2003 and 2009; 50.0% of the increase was attributable to an increase in primary cesarean delivery. Among the documented indications, nonreassuring fetal status, arrest of dilation, multiple gestation, pre-eclampsia, suspected macrosomia, and maternal request increased over time, while arrest of descent, malpresentation, maternal-fetal indications, and other obstetric indications (eg, cord prolapse, placenta previa) did not increase. The relative contributions of each indication to the total increase in primary cesarean rate were: Non-reassuring fetal status (32%), labor arrest disorders (18%), multiple gestation (16%), suspected macrosomia (10%), pre-eclampsia (10%), maternal request (8%), maternal-fetal conditions (5%), and other obstetric conditions (1%). CONCLUSION Primary cesarean births accounted for 50% of the increasing cesarean rate. Among primary cesareans, more subjective indications (nonreassuring fetal status and arrest of dilation) contributed larger proportions than more objective indications (malpresentation, maternal-fetal, and obstetric conditions). PMID:21646928

  7. Drug delivery across length scales.

    Science.gov (United States)

    Delcassian, Derfogail; Patel, Asha K; Cortinas, Abel B; Langer, Robert

    2018-02-20

    Over the last century, there has been a dramatic change in the nature of therapeutic, biologically active molecules available to treat disease. Therapies have evolved from extracted natural products towards rationally designed biomolecules, including small molecules, engineered proteins and nucleic acids. The use of potent drugs which target specific organs, cells or biochemical pathways, necessitates new tools which can enable controlled delivery and dosing of these therapeutics to their biological targets. Here, we review the miniaturisation of drug delivery systems from the macro to nano-scale, focussing on controlled dosing and controlled targeting as two key parameters in drug delivery device design. We describe how the miniaturisation of these devices enables the move from repeated, systemic dosing, to on-demand, targeted delivery of therapeutic drugs and highlight areas of focus for the future.

  8. Oral delivery of anticancer drugs

    DEFF Research Database (Denmark)

    Thanki, Kaushik; Gangwal, Rahul P; Sangamwar, Abhay T

    2013-01-01

    The present report focuses on the various aspects of oral delivery of anticancer drugs. The significance of oral delivery in cancer therapeutics has been highlighted which principally includes improvement in quality of life of patients and reduced health care costs. Subsequently, the challenges...... incurred in the oral delivery of anticancer agents have been especially emphasized. Sincere efforts have been made to compile the various physicochemical properties of anticancer drugs from either literature or predicted in silico via GastroPlus™. The later section of the paper reviews various emerging...... trends to tackle the challenges associated with oral delivery of anticancer drugs. These invariably include efflux transporter based-, functional excipient- and nanocarrier based-approaches. The role of drug nanocrystals and various others such as polymer based- and lipid based...

  9. Bioresponsive matrices in drug delivery

    Directory of Open Access Journals (Sweden)

    Ye George JC

    2010-11-01

    Full Text Available Abstract For years, the field of drug delivery has focused on (1 controlling the release of a therapeutic and (2 targeting the therapeutic to a specific cell type. These research endeavors have concentrated mainly on the development of new degradable polymers and molecule-labeled drug delivery vehicles. Recent interest in biomaterials that respond to their environment have opened new methods to trigger the release of drugs and localize the therapeutic within a particular site. These novel biomaterials, usually termed "smart" or "intelligent", are able to deliver a therapeutic agent based on either environmental cues or a remote stimulus. Stimuli-responsive materials could potentially elicit a therapeutically effective dose without adverse side effects. Polymers responding to different stimuli, such as pH, light, temperature, ultrasound, magnetism, or biomolecules have been investigated as potential drug delivery vehicles. This review describes the most recent advances in "smart" drug delivery systems that respond to one or multiple stimuli.

  10. Continuous Delivery and Quality Monitoring

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    After introducing Continuous Delivery, I will switch the topic and try to answer the question how much should we invest in quality and how to do it efficiently. My observations reveal that software quality is often considered as the slo...

  11. Technical Writing: Past, Present and Future

    Science.gov (United States)

    Mathes, J. C. (Compiler); Pinelli, T. E. (Compiler)

    1981-01-01

    The training of technical writers and the objectives of such education are discussed. Special emphasis was placed on the communication between technical personnel and non-technical personnel. The liabilities that affect technical writers were also discussed.

  12. Standard technical specifications for Babcock and Wilcox pressurized water reactors. Revision 4. Technical report

    International Nuclear Information System (INIS)

    Virgilio, M.J.

    1980-10-01

    The Standard Technical Specifications for Babcock and Wilcox Pressurized Water Reactors (BandW-STS) is a generic document prepared by the U.S. NRC for use in the licensing process. The BandW-STS provide applicants with model specifications to be used in formulation plant-specific technical specifications required by 10 CFR Part 50, Section 50.36, which set forth the specific characteristics of the facility and the conditions for its operation that are required to provide adequate protection to the health and safety of the public. This document is revised periodically to reflect current licensing requirements

  13. Organoclays for drug delivery Systems

    OpenAIRE

    Canovas Creus, Alba

    2008-01-01

    Modified clays can be used as carriers of drugs due to their suitable properties and structure in order to achieve improvements in drug delivery. The study of this thesis starts with an introduction to mineral clays and its classification, properties and characterization, then deepens into modified clays (properties, comparison with mineral clays, applications and procedure of modification). Another chapter is focused in drug delivery: definition, its difficulties nowadays and the different w...

  14. Improved Management of the Technical Interfaces Between the Hanford Tank Farm Operator and the Hanford Waste Treatment Plant - 13383

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, Garth M. [Bechtel National Inc., 2435 Stevens Center Place, Richland, Washington, 99352 (United States); Saunders, Scott A. [Washington River Protection Solutions, P.O. Box 850, Richland, Washington, 99352 (United States)

    2013-07-01

    The Department of Energy (DOE) is constructing the Waste Treatment and Immobilization Plant (WTP) at the Hanford site in Washington to treat and immobilize approximately 114 million gallons of high level radioactive waste (after all retrievals are accomplished). In order for the WTP to be designed and operated successfully, close coordination between the WTP engineering, procurement, and construction contractor, Bechtel National, Inc. and the tank farms operating contractor (TOC), Washington River Protection Solutions, LLC, is necessary. To develop optimal solutions for DOE and for the treatment of the waste, it is important to deal with the fact that two different prime contractors, with somewhat differing contracts, are tasked with retrieving and delivering the waste and for treating and immobilizing that waste. The WTP and the TOC have over the years cooperated to manage the technical interface. To manage what is becoming a much more complicated interface as the WTP design progresses and new technical issues have been identified, an organizational change was made by WTP and TOC in November of 2011. This organizational change created a co-located integrated project team (IPT) to deal with mutual and interface issues. The Technical Organization within the One System IPT includes employees from both TOC and WTP. This team has worked on a variety of technical issues of mutual interest and concern. Technical issues currently being addressed include: - The waste acceptance criteria; - Waste feed delivery and the associated data quality objectives (DQO); - Evaluation of the effects of performing a riser cut on a single shell tank on WTP operations; - The disposition of secondary waste from both TOC and WTP; - The close coordination of the TOC double shell tank mixing and sampling program and the Large Scale Integrated Test (LSIT) program for pulse jet mixers at WTP along with the associated responses to the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation

  15. Improved Management of the Technical Interfaces Between the Hanford Tank Farm Operator and the Hanford Waste Treatment Plant - 13383

    International Nuclear Information System (INIS)

    Duncan, Garth M.; Saunders, Scott A.

    2013-01-01

    The Department of Energy (DOE) is constructing the Waste Treatment and Immobilization Plant (WTP) at the Hanford site in Washington to treat and immobilize approximately 114 million gallons of high level radioactive waste (after all retrievals are accomplished). In order for the WTP to be designed and operated successfully, close coordination between the WTP engineering, procurement, and construction contractor, Bechtel National, Inc. and the tank farms operating contractor (TOC), Washington River Protection Solutions, LLC, is necessary. To develop optimal solutions for DOE and for the treatment of the waste, it is important to deal with the fact that two different prime contractors, with somewhat differing contracts, are tasked with retrieving and delivering the waste and for treating and immobilizing that waste. The WTP and the TOC have over the years cooperated to manage the technical interface. To manage what is becoming a much more complicated interface as the WTP design progresses and new technical issues have been identified, an organizational change was made by WTP and TOC in November of 2011. This organizational change created a co-located integrated project team (IPT) to deal with mutual and interface issues. The Technical Organization within the One System IPT includes employees from both TOC and WTP. This team has worked on a variety of technical issues of mutual interest and concern. Technical issues currently being addressed include: - The waste acceptance criteria; - Waste feed delivery and the associated data quality objectives (DQO); - Evaluation of the effects of performing a riser cut on a single shell tank on WTP operations; - The disposition of secondary waste from both TOC and WTP; - The close coordination of the TOC double shell tank mixing and sampling program and the Large Scale Integrated Test (LSIT) program for pulse jet mixers at WTP along with the associated responses to the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation

  16. Levodopa delivery systems: advancements in delivery of the gold standard.

    Science.gov (United States)

    Ngwuluka, Ndidi; Pillay, Viness; Du Toit, Lisa C; Ndesendo, Valence; Choonara, Yahya; Modi, Girish; Naidoo, Dinesh

    2010-02-01

    Despite the fact that Parkinson's disease (PD) was discovered almost 200 years ago, its treatment and management remain immense challenges because progressive loss of dopaminergic nigral neurons, motor complications experienced by the patients as the disease progresses and drawbacks of pharmacotherapeutic management still persist. Various therapeutic agents have been used in the management of PD, including levodopa (l-DOPA), selegiline, amantadine, bromocriptine, entacapone, pramipexole dihydrochloride and more recently istradefylline and rasagiline. Of all agents, l-DOPA although the oldest, remains the most effective. l-DOPA is easier to administer, better tolerated, less expensive and is required by almost all PD patients. However, l-DOPA's efficacy in advanced PD is significantly reduced due to metabolism, subsequent low bioavailability and irregular fluctuations in its plasma levels. Significant strides have been made to improve the delivery of l-DOPA in order to enhance its bioavailability and reduce plasma fluctuations as well as motor complications experienced by patients purportedly resulting from pulsatile stimulation of the striatal dopamine receptors. Drug delivery systems that have been instituted for the delivery of l-DOPA include immediate release formulations, liquid formulations, dispersible tablets, controlled release formulations, dual-release formulations, microspheres, infusion and transdermal delivery, among others. In this review, the l-DOPA-loaded drug delivery systems developed over the past three decades are elaborated. The ultimate aim was to assess critically the attempts made thus far directed at improving l-DOPA absorption, bioavailability and maintenance of constant plasma concentrations, including the drug delivery technologies implicated. This review highlights the fact that neuropharmaceutics is at a precipice, which is expected to spur investigators to take that leap to enable the generation of innovative delivery systems for the

  17. Technical Support Essentials Advice to Succeed in Technical Support

    CERN Document Server

    Sanchez, Andrew

    2010-01-01

    Technical Support Essentials is a book about the many facets of technical support. It attempts to provide a wide array of topics to serve as points of improvement, discussion, or simply topics that you might want to learn. The topics range from good work habits to the way technical supportgroups establish their own style of work. This book applies theories, models, and concepts synthesized from existing research in other fields-such as management, economics, leadership, and psychology-and connects them to technical support. The goal is to build on the work of others and allow their success to

  18. Technical standards in the law of technical safety

    International Nuclear Information System (INIS)

    Marburger, P.

    1985-01-01

    Technical standards are of great importance for the closer definition of inexact terms of law, for instance ''generally accepted technical rules'', ''state of the art'', ''state of science and technology'' or similar normative terms, in the law of technical safety. The paper discusses with whom the authority for regulating this sector of law rests, deals with the different ways of how technical standards are used by the law (''anticipated expert opinion'', reference to such standards in law and administration) and points out demands on the procedure of standardization. (orig.) [de

  19. Study on advanced systematic function of the JNC geological disposal technical information integration system. Research document

    International Nuclear Information System (INIS)

    Ishihara, Yoshinao; Fukui, Hiroshi; Sagawa, Hiroshi; Matsunaga, Kenichi; Ito Takaya

    2004-02-01

    In this study, while attaining systematization about the technical know-how mutually utilized between geology environmental field, disposal technology (design) field and safety assessment field, the share function of general information in which the formation of an information share and the use promotion between the technical information management databases built for every field were aimed at as an advancement of the function of JNC Geological Disposal Technical Information Integration System considered, and the system function for realizing considered in integration of technical information. (1) Since the concrete information about geology environment which is gradually updated with progress of stratum disposal research, or increases in reflected suitable for research of design and safety assessment. After arranging the form suitable for systematizing technical information, while arranging the technical information in both the fields of design and safety assessment with the form of two classes based on tasks/works, it systematized planning adjustment about delivery of technical information with geology environmental field. (2) In order to aim at integration of 3-fields technical information of geological disposal, based on the examination result of systematization of technical information, the function of mutual use of the information managed in two or more databases was considered. Moreover, while considering system functions, such as management of the use history of technical information, connection of information use, and a notice of common information, the system operation windows in consideration of the ease of operation was examined. (author)

  20. METHOD OF CHOOSING THE TECHNOLOGY OF VEHICLE OPERATION ON DELIVERY ROUTES

    Directory of Open Access Journals (Sweden)

    Ye. Nagornyi

    2014-10-01

    Full Text Available A method for determining the technology of vehicles operation on delivery (team routes, which allows to determine the optimal sequence of cargo delivery to customers by vehicles of certain capacity in order to meet the requirements of cargo owners regarding the conditions of service is offered. Recommendations for creation of an automated system of forming the technology of vehicles operation on delivery routes are developed.