WorldWideScience

Sample records for tech rep ne-317

  1. High Tech

    OpenAIRE

    Manterola, Javier; Fernández Casado, S.A., Carlos

    1987-01-01

    "High Tech" is an architectural movement that emphasizes the technological dimension of the building as expression means. Its research includes the diverse structures composing the building: resistance, closing, services, distribution and communications. Its results are unequal since not all the buildings rising from this movement are high technology and already are other buildings not enrolled in this movement. Renzo Piano, Richard Rogers and Norman Foster are its main representatives.

  2. República Argentina

    OpenAIRE

    Centro de Estudios Sudamericanos

    2008-01-01

    El sistema de gobierno en la Argentina adopta la forma representativa, republicana y federal (Constitución Nacional, art. 1º).Por su extensión -que corresponden al Continente Americano; al Continente Antártico (incluyendo las Islas Orcadas del Sur) y las islas australes (Georgias del Sur y Sandwich del Sur)- ocupa el cuarto lugar entre los países americanos (después de Canadá, Estados Unidos de América y la República Federativa del Brasil) y el séptimo a nivel mundial. Con una población de má...

  3. República Argentina

    OpenAIRE

    Centro de Estudios Sudamericanos (CENSUD)

    2008-01-01

    El sistema de gobierno en la Argentina adopta la forma representativa, republicana y federal (Constitución Nacional, art. 1º).Por su extensión -que corresponden al Continente Americano; al Continente Antártico (incluyendo las Islas Orcadas del Sur) y las islas australes (Georgias del Sur y Sandwich del Sur)- ocupa el cuarto lugar entre los países americanos (después de Canadá, Estados Unidos de América y la República Federativa del Brasil) y el séptimo a nivel mundial. Con una población de má...

  4. High Tech

    Directory of Open Access Journals (Sweden)

    Manterola, Javier

    1987-02-01

    Full Text Available "High Tech" is an architectural movement that emphasizes the technological dimension of the building as expression means. Its research includes the diverse structures composing the building: resistance, closing, services, distribution and communications. Its results are unequal since not all the buildings rising from this movement are high technology and already are other buildings not enrolled in this movement. Renzo Piano, Richard Rogers and Norman Foster are its main representatives.

    "High Tech" es un movimiento arquitectónico que enfatiza la dimensión tecnológica del edificio como medio de expresión. Su investigación se fija en las diversas estructuras que configuran el edificio, la resistente, la de cerramiento, la de servicios, la de distribución y comunicaciones. Sus resultados son desiguales pues no todos los edificios que surgen de este movimiento son alta tecnología y muchos otros no inscritos en dicho movimiento sí lo son. Renzo Piano, Richard Rogers y Norman Foster son sus representantes más destacados.

  5. RepA and RepB exert plasmid incompatibility repressing the transcription of the repABC operon.

    Science.gov (United States)

    Pérez-Oseguera, Angeles; Cevallos, Miguel A

    2013-11-01

    Rhizobium etli CFN42 has a multipartite genome composed of one chromosome and six large plasmids with low copy numbers, all belonging to the repABC plasmid family. All elements essential for replication and segregation of these plasmids are encoded within the repABC operon. RepA and RepB direct plasmid segregation and are involved in the transcriptional regulation of the operon, and RepC is the initiator protein of the plasmid. Here we show that in addition to RepA (repressor) and RepB (corepressor), full transcriptional repression of the operon located in the symbiotic plasmid (pRetCFN42d) of this strain requires parS, the centromere-like sequence, and the operator sequence. However, the co-expression of RepA and RepB is sufficient to induce the displacement of the parental plasmid. RepA is a Walker-type ATPase that self associates in vivo and in vitro and binds specifically to the operator region in its RepA-ADP form. In contrast, RepA-ATP is capable of binding to non-specific DNA. RepA and RepB form high molecular weight DNA-protein complexes in the presence of ATP and ADP. RepA carrying ATP-pocket motif mutations induce full repression of the repABC operon without the participation of RepB and parS. These mutants specifically bind the operator sequence in their ATP or ADP bound forms. In addition, their expression in trans exerts plasmid incompatibility against the parental plasmid. RepA and RepB expressed in trans induce plasmid incompatibility because of their ability to repress the repABC operon and not only by their capacity to distort the plasmid segregation process.

  6. Design Tech High School: d.tech

    Science.gov (United States)

    EDUCAUSE, 2015

    2015-01-01

    A Bay Area charter high school, d.tech develops "innovation-ready" students by combining content knowledge with the design thinking process while fostering a sense of autonomy and purpose. The academic model is grounded in self-paced learning through a flex schedule, high standards, and design thinking through a four-year design…

  7. Utshitsja drug u druga / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps uuendustest koolide õppekavades, õpetajate täienduskoolituse tähtsusest, kutsehariduse arengust, tasuta toitlustamisest põhi- ja kutsekoolides, õpetajate palkadest

  8. Utshitsja drug u druga / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps uuendustest koolide õppekavades, õpetajate täienduskoolituse tähtsusest, kutsehariduse arengust, tasuta toitlustamisest põhi- ja kutsekoolides, õpetajate palkadest

  9. High-Tech Architecture

    Directory of Open Access Journals (Sweden)

    Özlem Eşsiz

    1999-05-01

    Full Text Available The technological development in building and construction area, bring with the new construction systems and the new products. The aim of this study is to define the High Tech concept, and set the common and basic characteristics of High Tech applications. During 1970’s High Tech was born and developed in Britain. Especially British Architects Richard Rogers, Michael Hopkins, Norman Foster, Nicholas Grimshaw and Ian Ritchie are the leaders of this style. Their architecture show the machine aesthetic and use of industrial revoluation materials such as glass and steel. The reasons for wide usage of this technology in building constructions are; the ease of renewing the structural and installation systems by the changing technology and giving monumentality to the prestige buildings. High Tech building which we have many examples of give their occupants a lot of opportunities and also they can adapt itself to the time.

  10. HI-TECH OLYMPICS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The only Chinese company in The Olympic Partner Program, Lenovo supplies hi-tech in return for worldwide rights to Olympic logos Nineteen eighty-four was a lucky year for China as the country resumed its seat on the

  11. República del Paraguay

    OpenAIRE

    Centro de Estudios Sudamericanos

    2008-01-01

    La República del Paraguay adopta para su gobierno la democracia representativa, participativa y pluralista, fundada en el reconocimiento de la dignidad humana. Está ubicado en el corazón de América del Sur, dividido por el Río Paraguay en dos regiones, Oriental y Occidental o Chaco. Es un país mediterráneo, ya que no posee costas marítimas, así como lo es su vecino Bolivia, pero riegan sus costas dos ríos importantes, el Paraguay y el Paraná que desembocan en el Río de la Plata y que son util...

  12. High-tech entrepreneurship

    DEFF Research Database (Denmark)

    Bernasconi, Michel; Harris, Simon; Mønsted, Mette

    ; entrepreneurial finance; marketing technological innovations; and high-tech incubation management. Including case studies to give practical insights into genuine business examples, this comprehensive book has a distinctly 'real-world' focus throughout.Edited by a multi-national team, this comprehensive book......High-tech businesses form a crucial part of entrepreneurial activity - in some ways representing very typical examples of entrepreneurship, yet in some ways representing quite different challenges. The uncertainty in innovation and advanced technology makes it difficult to use conventional economic...... planning models, and also means that the management skills used in this area must be more responsive to issues of risk, uncertainty and evaluation than in conventional business opportunities. Whilst entrepreneurial courses do reflect the importance of high-tech businesses, they often lack the resources...

  13. Minister Reps valetas kantslerit vallandades / Urmo Soonvald

    Index Scriptorium Estoniae

    Soonvald, Urmo, 1973-

    2006-01-01

    Kuigi haridus- ja teadusminister Mailis Reps ütles juulikuus, et ta loodab ministeeriumi kantsleri Jaan Kallasega kokkuleppele jõuda, oli tal selleks ajaks juba uus kantsler välja valitud, väidab autor

  14. República Federativa de Brasil

    OpenAIRE

    Centro de Estudios Sudamericanos

    2007-01-01

    Brasil, es un Estado organizado como una república federal, con una forma de gobierno democrática representativa y participativa. La república está organizada en 27 estados (26 más el Distrito Federal donde está ubicada la capital nacional, Brasilia). (Párrafo extraído del texto a modo de resumen) Instituto de Relaciones Internacionales (IRI)

  15. Nalco Fuel Tech

    Energy Technology Data Exchange (ETDEWEB)

    Michalak, S.

    1995-12-31

    The Nalco Fuel Tech with its seat at Naperville (near Chicago), Illinois, is an engineering company working in the field of technology and equipment for environmental protection. A major portion of NALCO products constitute chemical materials and additives used in environmental protection technologies (waste-water treatment plants, water treatment, fuel modifiers, etc.). Basing in part on the experience, laboratories and RD potential of the mother company, the Nalco Fuel Tech Company developed and implemented in the power industry a series of technologies aimed at the reduction of environment-polluting products of fuel combustion. The engineering solution of Nalco Fuel Tech belong to a new generation of environmental protection techniques developed in the USA. They consist in actions focused on the sources of pollutants, i.e., in upgrading the combustion chambers of power engineering plants, e.g., boilers or communal and/or industrial waste combustion units. The Nalco Fuel Tech development and research group cooperates with leading US investigation and research institutes.

  16. Tech Gets Physical

    Science.gov (United States)

    Ravage, Barbara

    2011-01-01

    As colleges push for increased efficiencies, facilities departments nationwide are turning more and more to high-tech approaches. Nowhere has this trend been more visible than in the realm of energy consumption, where managers hope to extract significant cost savings. Technology is helping facilities managers achieve significant efficiencies,…

  17. High tech cheating.

    Science.gov (United States)

    Harper, Mary G

    2006-12-01

    The use of technology has enhanced the convenience, flexibility, and efficiency of both preparatory and continuing education. Unfortunately, academic dishonesty, including plagiarism, has shown a positive correlation with the increased use of technology in education. A review of the literature related to unintended outcomes of the use of technology in nursing education and continuing education was conducted to determine the ethical implications for the nursing profession. Although nursing research dealing with academic and professional misconduct is sparse, evidence suggests that academic dishonesty is a predictor of workplace dishonesty. Given this correlation between unethical classroom behavior and unethical clinical behavior, efforts to staunch academic dishonesty may help allay professional misconduct. A combination of high tech and low tech methods may be used to minimize unethical behaviors among students and practicing professional nurses in order to maintain the integrity of the profession.

  18. República del Perú

    OpenAIRE

    Centro de Estudios Sudamericanos

    2006-01-01

    La República del Perú es un Estado organizado como una república unitaria, con una forma de gobierno democrática representativa y participativa. La población es de 25.662 millones de habitantes, siendo el 47% de origen indígena. La población urbana representa el 72,3% y la rural el 27,7% de la población total. Las mayores concentraciones de población se encuentran en la franja costera y en algunos núcleos urbanos de la sierra andina. La densidad poblacional es de 19 habitantes por k...

  19. The TechSAT program

    Science.gov (United States)

    Shachar, M.; Lapid, P.

    1992-12-01

    The TechSAT project is described which is intended to establish a wide academic infrastructure for the development of new space technologies. A TechSAT satellite will be used for educational purposes by the academic staff and students as well as by radio amateurs. Tech SAT is a microsatellite weighing 50 kg with 45x45x45 cm dimensions. It is based on a Nadir pointing 3D stabilized platform with body mounted solar panels. The TechSAT hardware includes an autonomous attitude control system, a power supply system, and an onboard computer. Command control and telemetry systems will be based on the amateur radio communications payload.

  20. The replication origin of a repABC plasmid

    Directory of Open Access Journals (Sweden)

    Cevallos Miguel A

    2011-06-01

    Full Text Available Abstract Background repABC operons are present on large, low copy-number plasmids and on some secondary chromosomes in at least 19 α-proteobacterial genera, and are responsible for the replication and segregation properties of these replicons. These operons consist, with some variations, of three genes: repA, repB, and repC. RepA and RepB are involved in plasmid partitioning and in the negative regulation of their own transcription, and RepC is the limiting factor for replication. An antisense RNA encoded between the repB-repC genes modulates repC expression. Results To identify the minimal region of the Rhizobium etli p42d plasmid that is capable of autonomous replication, we amplified different regions of the repABC operon using PCR and cloned the regions into a suicide vector. The resulting vectors were then introduced into R. etli strains that did or did not contain p42d. The minimal replicon consisted of a repC open reading frame under the control of a constitutive promoter with a Shine-Dalgarno sequence that we designed. A sequence analysis of repC revealed the presence of a large A+T-rich region but no iterons or DnaA boxes. Silent mutations that modified the A+T content of this region eliminated the replication capability of the plasmid. The minimal replicon could not be introduced into R. etli strain containing p42d, but similar constructs that carried repC from Sinorhizobium meliloti pSymA or the linear chromosome of Agrobacterium tumefaciens replicated in the presence or absence of p42d, indicating that RepC is an incompatibility factor. A hybrid gene construct expressing a RepC protein with the first 362 amino acid residues from p42d RepC and the last 39 amino acid residues of RepC from SymA was able to replicate in the presence of p42d. Conclusions RepC is the only element encoded in the repABC operon of the R. etli p42d plasmid that is necessary and sufficient for plasmid replication and is probably the initiator protein. The ori

  1. RepA-WH1 prionoid

    Science.gov (United States)

    de la Espina, Susana Moreno-Díaz; Fernández-Tresguerres, M Elena; Gasset-Rosa, Fátima

    2011-01-01

    The intricate complexity at the molecular and cellular levels of the processes leading to the development of amyloid proteinopathies is somehow counterbalanced by their common, universal structural basis. The later has fueled the quest for suitable model systems to study protein amyloidosis under quasi-physiological conditions in vitro and in simpler organisms in vivo. Yeast prions have provided several of such model systems, yielding invaluable insights on amyloid structure, dynamics and transmission. However, yeast prions, unlike mammalian PrP, do not elicit any proteinopathy. We have recently reported that engineering RepA-WH1, a bacterial DNA-toggled protein conformational switch (dWH1→mWH1) sharing some analogies with nucleic acid-promoted PrPC→PrPSc replication, enables control on protein amyloidogenesis in vitro. Furthermore, RepA-WH1 gives way to a non-infectious, vertically-transmissible (from mother to daughter cells) amyloid proteinopathy in Escherichia coli. RepA-WH1 amyloid aggregates efficiently promote aging in bacteria, which exhibit a drastic lengthening in generation time, a limited number of division cycles and reduced fitness. The RepA-WH1 prionoid opens a direct means to untangle the general pathway(s) for protein amyloidosis in a host with reduced genome and proteome. PMID:21293179

  2. Planning a Successful Tech Show

    Science.gov (United States)

    Nikirk, Martin

    2011-01-01

    Tech shows are a great way to introduce prospective students, parents, and local business and industry to a technology and engineering or career and technical education program. In addition to showcasing instructional programs, a tech show allows students to demonstrate their professionalism and skills, practice public presentations, and interact…

  3. New Tech, New Ties:

    DEFF Research Database (Denmark)

    Ling, Richard

    regardless of where they are. But when we are engaged in these intimate conversations with absent friends, what happens to our relationship with the people who are actually in the same room with us? In New Tech, New Ties, Rich Ling examines how the mobile telephone affects both kinds of interactions......—those mediated by mobile communication and those that are face to face. Ling finds that through the use of various social rituals the mobile telephone strengthens social ties within the circle of friends and family—sometimes at the expense of interaction with those who are physically present—and creates what he...... calls "bounded solidarity." Ling argues that mobile communication helps to engender and develop social cohesion within the family and the peer group. Drawing on the work of Emile Durkheim, Erving Goffman, and Randall Collins, Ling shows that ritual interaction is a catalyst for the development of social...

  4. Vigor Clean Tech Inc.

    Energy Technology Data Exchange (ETDEWEB)

    Brubacher-Cressman, Dale [Vigor Clean Tech Inc. (Canada)

    2011-07-01

    On May 5, 2011, the Ontario Waterpower Association hosted the emergent hydro workshop in Peterborough. The first technology presented by Vigor Clean Tech Inc. was a system with a vertical axis which is supported by a floating structure and can provide 10's of kWs. The second one is the PowerPipe, an in-conduit system which can be implemented in existing or new conduits and that generates electricity from excess head pressure in rapidly flowing water transmission pipelines; the PowerPipe can be used in low head or incremental sites. With Vigor's technology it is possible to generate renewable energy economically on a small scale and to leverage under-utilized infrastructures. However, to date, few field applications have been carried out. This presentation provided information on a technology which has the potential to produce a steady supply of reliable renewable energy on a small scale.

  5. Tech transfer outreach

    Energy Technology Data Exchange (ETDEWEB)

    Liebetrau, S. (ed.)

    1992-01-01

    This document provides an informal summary of the conference workshop sessions. Tech Transfer Outreach '' was originally designed as an opportunity for national laboratory communications and technology transfer staff to become better acquainted and to discuss matters of mutual interest. When DOE field office personnel asked if they could attend, and then when one of our keynote speakers became a participant in the discussions, the actual event grew in importance. The conference participants--the laboratories and DOE representatives from across the nation--worked to brainstorm ideas. Their objective: identify ways to cooperate for effective (and cost-effective) technology transfer outreach. Thus, this proceedings is truly a product of ten national laboratories and DOE, working together. It candidly presents the discussion of issues and the ideas generated by each working group. The issues and recommendations are a consensus of their views.

  6. High Tech M&As

    DEFF Research Database (Denmark)

    Toppenberg, Gustav

    2013-01-01

    of findings are not applicable to the high-tech industry; in fact this industry has many additional challenges. In this study, we aim to explore the process of M&A in the high-tech industry by drawing on extant literature and empirical field work. The paper outlines a research project in progress which...... intends to provide theoretical, empirical and practical contributions in answering the research question: what role does Operations and IT play in creating value in high-tech M&As? The research adds a needed perspective on M&A literature by unveiling unique challenges and opportunities faced by the M...

  7. TechEdSat Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the Technical Education Satellite (TechEdSat) is to employ a small spacecraft to evaluate, demonstrate, and validate two new technologies for...

  8. de la República de Cuba

    Directory of Open Access Journals (Sweden)

    Daniel Ponce de León Lima

    2008-01-01

    Full Text Available Se presenta un esbozo de las estrategias a seguir para la inserción de la información edafológica en la Infraestructura de Datos Espaciales de la República de Cuba, a partir de un análisis del estado actual de desarrollo de la cartografía digital edafológica de Cuba y del desarrollo de bases de datos de la información de perfiles de suelo asociada. Se proponen una serie de tareas para lograr estos fines

  9. Mailis Reips : Prezhde vsego neobhodimo natshat / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2006-01-01

    Haridusminister Mailis Reps kakskeelse hariduse vajalikkusest vene õppekeelega koolides, noorte keeleoskusest, eesti keele õpetamise kvaliteedist, õpetajate eesti keele oskusest, õppetöö kvaliteedist

  10. A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication

    DEFF Research Database (Denmark)

    Oke, Muse; Kerou, Melina; Liu, Huanting

    2011-01-01

    that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. We show that SIRV Rep nicks the viral hairpin terminus, forming a covalent adduct between...... positioned active sites, each with a single tyrosine residue, work in tandem to catalyze DNA nicking and joining. We propose a novel mechanism for rudivirus DNA replication, incorporating the first known example of a Rep protein that is not linked to RCR. The implications for Rep protein function and viral...

  11. Tech Prep and the Rural Context.

    Science.gov (United States)

    Roth, Gene L.

    1996-01-01

    Discusses implementation of tech prep in rural areas and notes that relatively little research has been done on behalf of small town schools. Teachers' comments regarding tech prep implementation provide additional insight into the situation. (JOW)

  12. Lightweight Autonomous Underwater Vehicles (AUVs) performing coastal survey operations in REP 10A

    Science.gov (United States)

    Incze, Michael L.

    2011-11-01

    Lightweight Autonomous Underwater Vehicles (AUVs) were developed for Naval Special Warfare (NSW) Group 4 search and survey missions from a commercial AUV baseline (Iver 2) through integration of commercial off-the-shelf (COTS) hardware components, and through software development for enhanced on-board Command and Control functions. The development period was 1 year under a project sponsored by the Office of Naval Research TechSolutions Program Office. Hardware integration was completed by the commercial AUV vendor, OceanServer Technology, Inc., and software development was conducted by the Naval Undersea Warfare Center, Naval Oceanographic Office, and U MASS Dartmouth, with support from hardware and software application providers (YSI, Inc., Imagenex Technology Corp., and CARIS). At the conclusion of the integration and development period, an at-sea performance evaluation was scheduled for the Lightweight NSW AUVs with NSWG-4 personnel. The venue for this evaluation was the NATO exercise Recognized Environmental Picture 10A (REP 10A), hosted by Marinha Portuguesa, and coordinated by the Faculdade de Engenharia-Universidade do Porto. REP 10A offered an opportunity to evaluate the performance of the new AUVs and to explore the Concept of Operations (CONOPS) for employing them in military survey operations in shallow coastal waters. Shore- and ship-launched scenarios with launch/recovery by a single operator in a one-to-many coordinated survey, on-scene data product generation and visualization, data push to Reach Back Cells for product integration and enhancement, and survey optimization to streamline survey effort and timelines were included in the CONOPS review. Opportunities to explore employment of hybrid AUV fleets in Combined Force scenarios were also utilized. The Naval Undersea Warfare Center, Marinha Portuguesa, the Faculdade de Engenharia-Universidade do Porto, and OceanServer Technology, Inc., were the primary participants bringing in-water resources to

  13. Civismo, República e manuais escolares

    Directory of Open Access Journals (Sweden)

    Cleber Santos Vieira

    2012-01-01

    Full Text Available O artigo analisa aspectos do civismo no alvorecer da República brasileira, com ênfase na pesquisa sobre dois livros escolares: História do Brasil ensinada pela biografia de seus heróis, de Silvio Romero (1890; e A História de São Paulo pela biografia de seus nomes mais notáveis (1895, publicado por Tancredo Amaral. Por um lado, trata-se de apresentar nuances da Historia Magistra Vitae presentes nestes objetos da cultura material. Por outro, de destacar em que medida suas histórias foram pontuadas por divergências em torno da questão educação ou instrução cívica pela afirmação de um civismo de coloração regional, bem como palco de conflitos entre protagonistas do republicanismo paulista.

  14. CROPS : high tech agricultural robots

    NARCIS (Netherlands)

    Bontsema, J.; Hemming, J.; Pekkeriet, E.J.

    2014-01-01

    In the EU-funded CROPS (Clever Robots for Crops) project high tech robots are developed for site-specific spraying and selective harvesting of fruit and fruit vegetables. The harvesting robots are being designed to harvest high-value crops such as greenhouse vegetables, fruits in orchards and grapes

  15. Pensar la república : revolución y positivismo en los orígenes de la tercera república francesa

    OpenAIRE

    López Alcañiz, Vladimir

    2005-01-01

    El artículo reflexiona entorno la idea de república durante la tercera república francesa. El artículo incluye una bibliografía comentada referente al legado de la Revolución y los orígenes de la República. L’article reflexiona entorn la idea de república durant la tercera república francesa. L’article inclou una bibliografia comentada referent al llegat de la Revolució i els orígens de la República. The article focus on republic thought during the third french republic. It includes a b...

  16. PepGMV Rep-Protein Expression in Mammalian Cells

    Science.gov (United States)

    Chapa-Oliver, Angela María; Mejía-Teniente, Laura; García-Gasca, Teresa; Guevara-Gonzalez, Ramon Gerardo; Torres-Pacheco, Irineo

    2012-01-01

    The Geminiviruses genome is a small, single strand DNA that replicates in the plant cell nucleus. Analogous to animal DNA viruses, Geminiviruses depend on the host replication machinery to amplify their genomes and only supply the factors required to initiate their replication. Consequently, Geminiviruses remove the cell-cycle arrest and induce the host replication machinery using an endocycle process. They encode proteins, such as the conserved replication-associated proteins (Rep) that interact with retinoblastoma-like proteins in plants and alter the cell division cycle in yeasts. Therefore, the aim of this work is to analyze the impact of Pepper Golden Mosaic Virus (PepGMV) Rep protein in mammalian cells. Results indicate that the pTracer-SV40:Rep construction obtained in this work can be used to analyze the Rep protein effect in mammalian cells in order to compare the cell cycle regulation mechanisms in plants and animals. PMID:23170183

  17. República Saharaui: una nación cerca del olvido

    OpenAIRE

    Valdez Ugalde, María Cristina

    2010-01-01

    1. Párrafo de Inicio 2. Desarrollo a. República Saharaui o Sahara Occidental b. El gobierno de la República Saharaui c. La gente en la República Saharaui d. La ONU y la República Saharaui 3. Párrafo de Cierre 4. Referencias 5. Notas de enseñanza

  18. Running-gear Tech 2001; Fahrwerk-Tech 2001. Tagung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Dynamic driving characteristics, active safety and high comfort are conflicting goals which can be combined by active vehicle management systems. The conference discussed modern tools and methods in the fields of design, simulation and experiment. [German] Im Zielkonflikt zwischen Fahrdynamik, aktiver Sicherheit und Komfort bieten Fahrzeugregelsysteme enorme Moeglichkeiten. Systeme fuer Bremsen, Stabilisierung, Daempfung, Aufbaukontrolle und Fahrerassistenz werden in der Zukunft zu einem Fahrwerksmanagement verschmelzen. Diese Fahrzeugintelligenz erfordert moderne Tools und Methoden im Bereich Konzeption, Simulation und Versuch. Die Tagung Fahrwerk-Tech 2001 wird das Fahrwerk in dieser Gesamtheit betrachten und Experten aus den verschiedenen Bereichen zusammen bringen. (orig.)

  19. Specific functions of the Rep and Rep' proteins of porcine circovirus during copy-release and rolling-circle DNA replication

    Science.gov (United States)

    The roles of two porcine circovirus replication initiator proteins, Rep and Rep', in generating copy-release and rolling-circle DNA replication intermediates were determined. Rep uses the supercoiled closed-circular genome (ccc) to initiate leading-strand synthesis (identical to copy-release replica...

  20. High-tech meets end-user

    NARCIS (Netherlands)

    Steen, M.

    2008-01-01

    One challenge within the high-tech sector is to develop products that end users will actually need and will be able to use. One way of trying to match the design of high-tech products to the needs of end users, is to let researchers and designers interact with them via a human-centred design (HCD) a

  1. A República Mundial de Otfried Höffe

    Directory of Open Access Journals (Sweden)

    Diego Carlos Zanella

    2015-03-01

    Full Text Available Esse texto tem por objetivo apresentar em linhas gerais a proposta de Otfried Höffe sobre a república mundial. Para tanto, iniciar-se-á com o ponto de partida de Höffe, a saber, o fenômeno da globalização, de onde são apontadas as principais atividades e problemas da república mundial. Em seguida, passa-se a analisar os dois níveis da proposta, o nível nacional e o nível internacional ou global da república mundial. Por fim, concluir-se-á com uma tentativa de comparação da proposta de Höffe com a ideia de uma federação de Estados livres apresentada por Immanuel Kant em À paz perpétua.

  2. 3D printing with RepRap cookbook

    CERN Document Server

    Salinas, Richard

    2014-01-01

    A systematic guide consisting of over 100 recipes which focus on helping you understand the process of 3D printing using RepRap machines. The book aims at providing professionals with a series of working recipes to help make their fuzzy notions into real, saleable projects/objects using 3D printing technology. This book is for novice designers and artists who own a RepRap-based 3D printer, have fundamental knowledge of its working, and who desire to gain better mastery of the printing process. For the more experienced user, it will provide a handy visual resource, with side-by-side comparisons

  3. Images en mouvement stockage, repérage, indexation

    CERN Document Server

    Turner, James

    1998-01-01

    L'avènement puis la fusion des nouveaux modes de communication que sont l'informatique, les télécommunications et l'audiovisuel ont mis à la portée de tous une grande quantité d'images fixes et en mouvement dont la conservation et le repérage risquent de prendre des proportions démesurées. Le présent ouvrage veut offrir aux responsables de collection des repères pour aborder la problématique de l'indexation des images et faciliter l'accès des usagers à ces images.

  4. Mechatronics education at Virginia Tech

    Science.gov (United States)

    Bay, John S.; Saunders, William R.; Reinholtz, Charles F.; Pickett, Peter; Johnston, Lee

    1998-12-01

    The advent of more complex mechatronic systems in industry has introduced new opportunities for entry-level and practicing engineers. Today, a select group of engineers are reaching out to be more knowledgeable in a wide variety of technical areas, both mechanical and electrical. A new curriculum in mechatronics developed at Virginia Tech is starting to bring students from both the mechanical and electrical engineering departments together, providing them wit an integrated perspective on electromechanical technologies and design. The course is cross-listed and team-taught by faculty from both departments. Students from different majors are grouped together throughout the course, each group containing at least one mechanical and one electrical engineering student. This gives group members the ability to learn from one another while working on labs and projects.

  5. The 11th High-Tech Expo

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The 11th China Beijing International High-Tech Expo,themed as "high-tech Olympics and high-tech innovation",was rounded off successfully on the afternoon of May 25.The Expo,held as planned in such a special period of post-quake relief work,has shown us the power of technology and scientific spirit.It has not only given all the Chinese people the spiritual support and hope for the future but also opened a window for the international community to know more about the Beijing Oympic Games and the development of science and technology in China.

  6. Las Garrapatas de la República de Colombia

    Directory of Open Access Journals (Sweden)

    Osorno Mesa Ernesto

    1942-04-01

    Full Text Available El presente estudio comprende las especies de garrapatas colombianas conocidas, como también las de la República de Panamá. En las claves incluyo las especies descritas y halladas en Colombia. Las referencias fueron tomadas de las descripciones originales y de todas las publicaciones sobre garrapatas de los dos países.

  7. El movimiento no parlamentario en la Segunda República

    Directory of Open Access Journals (Sweden)

    Víctor ALBA

    2010-02-01

    Full Text Available Cuando se escribe sobre la Segunda República española se hace frecuente referencia a las derechas, los partidos republicanos y los socialistas. Menos frecuentes son las alusiones al movimiento narcosindicalista y casi nulas las que se relacionan con los partidos marxistas menores.

  8. Rehabilitation Education Program for Stroke (REPS): Learning and Practice Outcomes

    Science.gov (United States)

    McEwen, Sara; Szurek, Kristina; Polatajko, Helene J.; Rappolt, Susan

    2005-01-01

    Introduction: New research knowledge acquired from Web-based sources may have a better chance of being translated into practice when accompanied by additional educational strategies. This study was undertaken to investigate that hypothesis. Methods: The Rehabilitation Education Program for Stroke (REPS) combines a self-directed online learning…

  9. Las garrapatas de la república de colombia

    OpenAIRE

    Osorno Mesa Ernesto

    2012-01-01

    El presente estudio comprende las especies de garrapatas colombianas conocidas, como también las de la República de Panamá. En las claves incluyo las especies descritas y halladas en Colombia. Las referencias fueron tomadas de las descripciones originales y de todas las publicaciones sobre garrapatas de los dos países.

  10. Preventing Tech Aches: Using Smart Phones Wisely

    Science.gov (United States)

    ... Media Guidelines Copyright Permissions Preventing Tech Aches: Using Smart Phones Wisely BETHESDA, MD (Dec. 26, 2013) — If you received a new smart phone or tablet this holiday season, chances are you’ ...

  11. Human capital in low-tech manufacturing

    DEFF Research Database (Denmark)

    Hansen, Teis; Winther, Lars; Hansen, Ronnie Fibæk

    2014-01-01

    capital appears to be equally important for economic development in low-tech industries and, second, that the divide between the large urban regions, especially Copenhagen, and the rest of the country plays the primary role in explaining the geography of human capital. These findings stress the relevance......An essential feature associated with the rise of the knowledge economy has been the increasing focus on the importance of human capital as a precondition for economic growth. Human capital has been found to have a positive impact on the economic growth of high-tech industries, however......, the influence of human capital on the development of low-tech industries is yet to be analysed. This paper provides such an examination of low-tech industries based on an analysis of employment data within manufacturing industries in Denmark in the period 1993–2006. The findings highlight, first, that human...

  12. Overview of RepLab 2013: Evaluating online reputation monitoring systems

    NARCIS (Netherlands)

    Amigó, E.; Carrillo de Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Martín, T.; Meij, E.; de Rijke, M.; Spina, D.

    2013-01-01

    This paper summarizes the goals, organization, and results of the second RepLab competitive evaluation campaign for Online Reputation Management Systems (RepLab 2013). RepLab focused on the process of monitoring the reputation of companies and individuals, and asked participant systems to annotate

  13. Overview of RepLab 2012: Evaluating Online Reputation Management Systems

    NARCIS (Netherlands)

    Amigó, E.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.

    2012-01-01

    This paper summarizes the goals, organization and results of the first RepLab competitive evaluation campaign for Online Reputation Management Systems (RepLab 2012). RepLab focused on the reputation of companies, and asked participant systems to annotate different types of information on tweets

  14. Specific functions of the Rep and Rep׳ proteins of porcine circovirus during copy-release and rolling-circle DNA replication.

    Science.gov (United States)

    Cheung, Andrew K

    2015-07-01

    The roles of two porcine circovirus replication initiator proteins, Rep and Rep׳, in generating copy-release and rolling-circle DNA replication intermediates were determined. Rep uses the supercoiled closed-circular genome (ccc) to initiate leading-strand synthesis (identical to copy-release replication) and generates the single-stranded circular (ssc) genome from the displaced DNA strand. In the process, a minus-genome primer (MGP) necessary for complementary-strand synthesis, from ssc to ccc, is synthesized. Rep׳ cleaves the growing nascent-strand to regenerate the parent ccc molecule. In the process, a Rep׳-DNA hybrid containing the right palindromic sequence (at the origin of DNA replication) is generated. Analysis of the virus particle showed that it is composed of four components: ssc, MGP, capsid protein and a novel Rep-related protein (designated Protein-3).

  15. The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins

    DEFF Research Database (Denmark)

    Madsen, Louise; Kriegenburg, Franziska; Lages Lino Vala, Andrea;

    2011-01-01

    protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8...

  16. NASA Tech Briefs, February 2009

    Science.gov (United States)

    2009-01-01

    Tech Briefs are short announcements of innovations originating from research and development activities of the National Aeronautics and Space Administration. They emphasize information considered likely to be transferable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. Topics covered include: Measuring Low Concentrations of Liquid Water in Soil; The Mars Science Laboratory Touchdown Test Facility; Non-Contact Measurement of Density and Thickness Variation in Dielectric Materials; Compact Microwave Fourier Spectrum Analyzer; InP Heterojunction Bipolar Transistor Amplifiers to 255 GHz; Combinatorial Generation of Test Suites; In-Phase Power-Combined Frequency Tripler at 300 GHz; Electronic System for Preventing Airport Runway Incursions; Smaller but Fully Functional Backshell for Cable Connector; Glove-Box or Desktop Virtual-Reality System; Composite Layer Manufacturing with Fewer Interruptions; Improved Photoresist Coating for Making CNT Field Emitters; A Simplified Diagnostic Method for Elastomer Bond Durability; Complex Multifunctional Polymer/Carbon-Nanotube Composites; Very High Output Thermoelectric Devices Based on ITO Nanocomposites; Reducing Unsteady Loads on a Piggyback Miniature Submarine; Ultrasonic/Sonic Anchor; Grooved Fuel Rings for Nuclear Thermal Rocket Engines; Pulsed Operation of an Ion Accelerator; Autonomous Instrument Placement for Mars Exploration Rovers; Mission and Assets Database; TCP/IP Interface for the Satellite Orbit Analysis Program (SOAP); Trajectory Calculator for Finite-Radius Cutter on a Lathe; Integrated System Health Management Development Toolkit.

  17. A república paraense em festa (1890-1911)

    OpenAIRE

    MOURA, Daniella de Almeida

    2008-01-01

    A proposta desta dissertação é discutir a formação do poder simbólico da República Paraense nos seus primeiros anos (1890-1911), observando eventos como a mudança dos nomes de algumas ruas em homenagem ao novo regime, assim como a formulação do calendário republicano, com destaque para os festejos republicanos de 15 e 16 de novembro, datas da Proclamação da República e sua Aclamação no Pará, com o objetivo de analisar seus significados, organização e, principalmente, o entendimento da idéia d...

  18. Identification of Tilletia species using rep-PCR fingerprinting technique

    Directory of Open Access Journals (Sweden)

    Župunski Vesna

    2011-01-01

    Full Text Available Analyzing 167 non-processed seed samples of wheat, it was found that 145 samples (86.8 % were contaminated with Tilletia species, while 22 (13.2 % samples were not contaminated. By using rep-PCR fingerprinting technique, it was found that DNA isolates of T. tritici originated from Serbian wheat samples had 80 % similarity with positive control for T. tritici. One isolate shared similarity of 60% with T. tritici, T. controversa and T. laevis. It was supposed that this isolate belongs to T. bromi. Isolate of T. laevis shared a similarity of 70 % with isolates of T. tritici and T. controversa, while T. walkeri was more than 10 % similar with T. tritici, T. controversa and T. laevis. Although T. controversa and T. tritici had high percent of genetic similarity, they were clustered separately. Our results suggest that rep-PCR fingerprinting could be a useful tool for monitoring presence of morphologically similar Tilletia species in wheat production areas.

  19. Arduino & RepRap - Creating Wealth by Giving it Away

    DEFF Research Database (Denmark)

    2011-01-01

    , growth in wealth is longevity and prosperity. Is it possible to grow wealth independently of money? This talk will be from Adrian Bowyer - creator of RepRap, the open-source replicating 3D printer - and from David Cuartielles - creator of Arduino, the open-source microcontroller. Both projects have...... founded significant and growing industries - and hence significant and growing wealth - by giving away all the data required to build RepRaps and Arduinos completely free. They have also short-circuited most conventional industrial infrastructure by placing the ability to create wealth directly...... in the hands of private individuals. The presenters contend that this is the way of the future: companies, and - more importantly - those private individuals will be giving away their primary products and making a living on the sideline activities that such donations attract. Software has been heading...

  20. Airport Noise Tech Challenge Overview

    Science.gov (United States)

    Bridges, James

    2011-01-01

    The Supersonics Project, operating under NASA Aeronautics Mission Directorate#s Fundamental Aero Program, has been organized around the Technical Challenges that have historically precluded commercial supersonic flight. One of these Challenges is making aircraft that are capable of such high aerodynamic performance quiet enough around airports that they will not be objectionable. It is recognized that a successful civilian supersonic aircraft will be a system where many new technologies will come together, and for this to happen not only will new low noise propulsion concepts be required, but new engineering tools that predict the noise of the aircraft as these technologies are combined and compromised with the rest of the aircraft design. These are the two main objectives of the Airport Noise Tech Challenge. " ! As a Project in the Fundamental Aero Program, we work at a relatively low level of technology readiness. However, we have high level milestones which force us to integrate our efforts to impact systems-level activities. To keep the low-level work tied to delivering engineering tools and low-noise concepts, we have structured our milestones around development of the concepts and organized our activities around developing and applying our engineering tools to these concepts. The final deliverables in these milestones are noise prediction modules validated against the best embodiment of each concept. These will then be used in cross-disciplinary exercises to demonstrate the viability of aircraft designs to meet all the Technical Challenges. Some of the concepts being developed are shown: Fan Flow Diverters, Multi-jet Shielding, High-Aspect Ratio Embedded Nozzles, Plasma Actuated Instability Manipulation, Highly Variable Cycle Mixer- Ejectors, and Inverted Velocity Profiles. These concepts are being developed for reduced jet noise along with the design tools which describe how they perform when used in various aircraft configurations. Several key upcoming

  1. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication

    Science.gov (United States)

    Seyffert, Michael; Glauser, Daniel L.; Schraner, Elisabeth M.; de Oliveira, Anna-Paula; Mansilla-Soto, Jorge; Vogt, Bernd; Büning, Hildegard; Linden, R. Michael; Ackermann, Mathias; Fraefel, Cornel

    2017-01-01

    As their names imply, parvoviruses of the genus Dependovirus rely for their efficient replication on the concurrent presence of a helpervirus, such as herpesvirus, adenovirus, or papilloma virus. Adeno-associated virus 2 (AAV2) is such an example, which in turn can efficiently inhibit the replication of each helpervirus by distinct mechanisms. In a previous study we have shown that expression of the AAV2 rep gene is not compatible with efficient replication of herpes simplex virus 1 (HSV-1). In particular, the combined DNA-binding and ATPase/helicase activities of the Rep68/78 proteins have been shown to exert opposite effects on the replication of AAV2 and HSV-1. While essential for AAV2 DNA replication these protein activities account for the Rep-mediated inhibition of HSV-1 replication. Here, we describe a novel Rep mutant (Rep-D371Y), which displayed an unexpected phenotype. Rep-D371Y did not block HSV-1 replication, but still supported efficient AAV2 replication, at least when a double-stranded AAV2 genome template was used. We also found that the capacity of Rep-D371Y to induce apoptosis and a Rep-specific DNA damage response was significantly reduced compared to wild-type Rep. These findings suggest that AAV2 Rep-helicase subdomains exert diverging activities, which contribute to distinct steps of the AAV2 life cycle. More important, the novel AAV2 mutant Rep-D371Y may allow deciphering yet unsolved activities of the AAV2 Rep proteins such as DNA second-strand synthesis, genomic integration or packaging, which all involve the Rep-helicase activity. PMID:28125695

  2. Interpersonal Communication in High Tech Culture: Eastern or Western?

    Science.gov (United States)

    Isenhart, Myra W.

    1987-01-01

    Investigates interpersonal communication in a high tech organization to test the association between high tech organizations and Western styles of symbolic interaction. Takes a diagnostic, rather than prescriptive, approach to organizational change. (MM)

  3. Planning a Tech Prep Program in Hospitality. Final Report.

    Science.gov (United States)

    Chicago City Colleges, IL. Chicago City-Wide Coll.

    A project conducted to establish tech prep articulation training agreements between City Colleges of Chicago and several public secondary schools is described in this report. Project activities were as follows: (1) developed a handbook to define the tech prep experience and guide committee members on how tech prep can be a valuable asset to…

  4. Theoretical Study of Agricultural High-tech Industrialization

    Institute of Scientific and Technical Information of China (English)

    Jian; XU; Xianming; WU

    2013-01-01

    This paper introduces the characteristics of the agricultural high-tech industries,and points out that the agricultural high-tech industries are intelligence-intensive and knowledge-intensive industries with the characteristics of high investment,high risk,high value-added, which focuses on constant innovation,having strong horizontal and vertical linkages with other enterprises and showing the trend of internationalization.The connotation of agricultural high-tech industrialization is analyzed as follows:Agricultural high-tech industrialization is the process of transformation of the agricultural high-tech achievements to the agricultural high-tech industries; essentially the marketization and commercialization of agricultural high technology; the manifestation of scale and level of agricultural high-tech industries; the manifestation of social impact,social status and social role of agricultural high-tech industries.The development strategies are put forward for agricultural high-tech industrialization:(1) Bringing the research of agricultural high technology into the orbit of the market economy; (2) Implementing the new mechanism to closely link agricultural high technology with modern rural enterprises; (3) Building the agricultural high-tech team with a larger size and high level; (4) Further improving the construction of the agricultural high-tech industrial development zone; (5) Solving the issues concerning agricultural intellectual property and patent; (6) Increasing policy guidance and support efforts for agricultural high-tech industries.

  5. The High-Tech Industry and Its Workers

    Science.gov (United States)

    Kirk, James; Belovics, Robert

    2007-01-01

    The purpose of this article is to provide counselors, academic advisers, and career coaches with a basic understanding of the current state of the high-technology (high-tech) industry in the United States and the people who work in it. A profile of a high-tech worker is presented, several high-tech career developments are described, and selected…

  6. URBox : High tech energy and informal housing

    NARCIS (Netherlands)

    Cuperus, Y.J.; Smets, D.

    2011-01-01

    This paper reports on the URBox concept encompassing the high tech end of solar energy and informal low cost and affordable housing. It aims to contribute to solving the global energy crisis by building solar energy settlements in deserts where land is affordable and sunshine in abundance. First the

  7. Development of High-Tech Skills.

    Science.gov (United States)

    Theuerkauf, Walter E.

    High tech systems not only generate new structures in the production process, but also involve profound changes in job organization, which in turn imply that job qualifications must be modified. In view of the changes within engineering systems and the relevant technologies, it seems expedient to choose a curricular approach based on the concepts…

  8. Virginia Tech opens Engineering Communications Center

    OpenAIRE

    2006-01-01

    In an attempt to provide the engineers of the 21st Century with top-notch professional skills to complement their technical expertise, Virginia Tech, one of ten largest undergraduate engineering programs in the country, has opened an Engineering Communication Center.

  9. URBox : High tech energy and informal housing

    NARCIS (Netherlands)

    Cuperus, Y.J.; Smets, D.

    2011-01-01

    This paper reports on the URBox concept encompassing the high tech end of solar energy and informal low cost and affordable housing. It aims to contribute to solving the global energy crisis by building solar energy settlements in deserts where land is affordable and sunshine in abundance. First the

  10. Senior Military Colleges Meet At Virginia Tech

    OpenAIRE

    Lovegrove, Richard L.

    2003-01-01

    Representatives from the nation's six senior military colleges will hear from the Department of Defense and national Reserve Officer Training Corps (ROTC) commanders during the annual Senior Military Colleges Conference at Virginia Tech on Wednesday and Thursday, Sept. 17 and 18 at the Donaldson Brown Hotel and Conference Center.

  11. Virginia Tech student receives Student Leadership Award

    OpenAIRE

    Dickerson, Susan

    2004-01-01

    The Outstanding Undergraduate Student Leader Award is one of 10 University Student Leadership Awards given annually by Virginia Tech's Department of Student Activities in the Division of Student Affairs to recognize outstanding members, extraordinary achievements by an organization, advisers, volunteerism, and service-learning experiences.

  12. Planning and Designing Today's Career Tech Facility

    Science.gov (United States)

    Seaman, James

    2010-01-01

    During the past 20 years, career and technical education (CTE) has gone through significant changes. CTE has evolved in response to the changes technology has had on the job market. Preparing students for high-tech, high-skill job opportunities is the new focus. The facilities that house these programs, however, have not kept pace with these…

  13. Rep rated long life capacitor development: Phase 1 and 2

    Science.gov (United States)

    Galperin, I.; White, W.; Haskell, K.; Ennis, J.

    1984-09-01

    Polypropylene and polyolefin resins were characterized and processed into capacitor films. New capacitor films were developed--a post oriented processed, two layer polypropylene film and upgraded polyolefin film. Criteria for judging film quality were developed. Field life data were verified with paper/polypropylene capacitors on the Maxwell rep rate facility. A11 polypropylene film capacitors were developed with lifetimes in excess of 10 to the 7th power discharges at energy densities for the finished capacitor of 18.3 J/lb and projected to more than 20 J/lb.

  14. República: gobierno gerencial vs política

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Sánchez Ramos

    2008-01-01

    Full Text Available El presente artículo tiene como propósito revisar el modelo en el que se basó el Partido Acción Nacional (PAN, al gobernar en la presidencia de la República, con Vicente Fox como presidente, demostrando que descuidó la política al preferir los elementos organizacionales por encima de ésta y no reconociéndola como un mecanismo necesario para la disminución de las contradicciones en una sociedad con alta diferenciación social.

  15. A Economia da República Velha,1889-1930

    OpenAIRE

    Gustavo H. B. Franco; Luiz Aranha Correa do Lago

    2011-01-01

    1. Preâmbulo: transição, legado e desafios 2. Do Encilhamento ao Funding Loan 3. O Convênio de Taubaté: a defesa do café e do câmbio 4. O desempenho da economia de 1889 a 1913 em perspectiva 5. A primeira Guerra Mundial, e os “choques adversos” 6. A reconstrução da normalidade nos anos 1920 7. A economia brasileira ao final da República Velha 8. Bibliografia

  16. Stress Monitoring of Mulberry Plants by Finding Rep Using Hyperspectral Data

    Science.gov (United States)

    Bhosle, K.; Musande, V.

    2017-05-01

    Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP) is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680-800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  17. Mis saab sinu andekast lapsest? / Tõnis Lukas, Mailis Reps, Peeter Kreitzberg...[jt.] ; intervjueerinud Urve Eslas

    Index Scriptorium Estoniae

    2011-01-01

    Haridusteemalistele küsimustele vastavad haidusminister Tõnis Lukas (IRL), reformierakondlane Paul-Eerik Rummo, sotsiaaldemokraat Peeter Kreitzberg, keskerakondlane Mailis Reps ja Raivo Juurak roheliste nimekirjast

  18. Mycoplasma pneumoniae large DNA repetitive elements RepMP1 show type specific organization among strains.

    Directory of Open Access Journals (Sweden)

    Oxana Musatovova

    Full Text Available Mycoplasma pneumoniae is the smallest self-replicating bacterium with a streamlined genome of 0.81 Mb. Complete genome analysis revealed the presence of multiple copies of four large repetitive elements (designated RepMP1, RepMP2/3, RepMP4 and RepMP5 that are implicated in creating sequence variations among individual strains. Recently, we described RepMP1-associated sequence variations between reference strain M129 and clinical isolate S1 that involved three RepMP1-genes (i.e. mpn130, mpn137 and mpn138. Using PCR and sequencing we analyze 28 additional M. pneumoniae strains and demonstrate the existence of S1-like sequence variants in nine strains and M129-like variants in the remaining nineteen strains. We propose a series of recombination steps that facilitates transition from M129- to S1-like sequence variants. Next we examined the remaining RepMP1-genes and observed no other rearrangements related to the repeat element. The only other detected difference was varying numbers of the 21-nucleotide tandem repeats within mpn127, mpn137, mpn501 and mpn524. Furthermore, typing of strains through analysis of large RepMPs localized within the adhesin P1 operon revealed that sequence divergence involving RepMP1-genes mpn130, mpn137 and mpn138 is strictly type-specific. Once more our analysis confirmed existence of two highly conserved groups of M. pneumoniae strains.

  19. Commercial introduction of the Advanced NOxTECH system

    Energy Technology Data Exchange (ETDEWEB)

    Sudduth, B.C. [NOxTECH, Inc., Irvine, CA (United States)

    1997-12-31

    NOxTECH is BACT for diesel electric generators. Emissions of NO{sub x} are reduced 95% or more with substantial concurrent reductions in CO, particulates, and ROG`s. No engine modifications or other exhaust aftertreatments can remove all criteria pollutants as effectively as NOxTECH. The NOxTECH system reliably maintains NH{sub 3} slip below 2 ppm. Unlike other emissions controls, NOxTECH does not generate hazardous by-products. The Advanced NOxTECH system reduces the size, weight, and cost for BACT emissions reductions. Based on the operation of a 150 kW prototype, NOxTECH, Inc. is quoting commercial units for diesel electric generators. Advanced NOxTECH equipment costs about half as much as SCR systems, and NO{sub x} reduction can exceed 95% with guarantees for emissions compliance.

  20. A short pulse, high rep-rate microdischarge VUV source

    Science.gov (United States)

    Stephens, Jacob; Fierro, Andrew; Dickens, James; Neuber, Andreas; CenterPulsed Power; Power Electronics Team

    2013-09-01

    A MOSFET based high voltage pulser is utilized to excite a microdischarge (MD), or microdischarge array (MDA) with pulsed voltages of up to 1 kV, with risetime and FWHM on the order of 10 ns and 30 ns, respectively. Additionally, the pulser is capable of pulsing at rep-rates in excess of 35 MHz. However, for these experiments the rep-rate was set on the order of 1 MHz, so as to limit excess energy deposition into the background gas and optimize the energy efficiency of VUV generation. Using VUV capable spectral diagnostics, the VUV emission of the MDs for various pressures (50-800 + Torr) and gases, focused on argon, argon-hydrogen mixtures, and neon-hydrogen mixtures (all of which provide strong emission at λ VUV emission is characterized and compared to results from transient fluid modeling of the MDA. For instance, the MDA turn-on time is recorded to be about 15 ns, which matches the full plasma development time in the model, and the MDA self- capacitance largely determines the turn-off behavior. This research was supported by an AFOSR grant on the Physics of Distributed Plasma Discharges and fellowships from the National Physical Sciences Consortium, supported by Sandia National Laboratories.

  1. Patterns of Technological Innovation: A Comparative Analysis between Low-tech and High-tech Industries in Brazil

    Directory of Open Access Journals (Sweden)

    Raimundo Eduardo Silveira Fontenele

    2016-06-01

    Full Text Available This paper is intended to contribute to the knowledge about the patterns of innovations in different economic sectors. Hence, the general objective is to assess the differences in rates, directions, sources and efforts of innovations between low-tech and high-tech industries in Brazil. The analysis is based on the database of a survey on innovation (PINTEC conducted by IBGE. The sample includes 8,578 innovative Brazilian companies surveyed from selected low-tech industries (food and textiles manufactures and high-tech industries (vehicles and electronics industries. Descriptive and factorial correspondence analysis were used to identify the variables regarding rates, directions, sources and efforts of innovation that discriminate the low-tech industries of high-tech. The results confirm that low-tech industries differ from high tech ones in all pattern of innovations dimensions analyzed. Hence, low tech industries, compared to high-tech ones, are less innovative, innovate more in process, have fewer people dedicated to R&D, present suppliers as the most significant source of information and is a larger user of Government funding for the purchase of machinery and equipment. On the other hand, the high-tech industries are more innovative, innovate more in products, have more people dedicated to R&D, search for information of other groups of companies, customers and competitors, and their larger use of public financing is for investing in R&D.

  2. Differentiating Criteria for High-Tech Companies

    Directory of Open Access Journals (Sweden)

    Rostek Katarzyna

    2014-12-01

    Full Text Available Manufacturing companies operating within the high-technology sector are of interest to science, industry and national authorities because of the special economic importance attached to them. However, in order to investigate the condition of those companies, support their growth and monitor the effects of the aid awarded to them, it is first necessary to properly identify the business entities belonging to that sector. To identify the entities belonging to the high-technology industry, it is necessary to perform a sequence of activities which form the procedural algorithm. Usefulness of the algorithm has been verified using the example of a group of Warsaw high-tech companies which were subject to investigation under the European project Warsaw Entrepreneurship Forum. The algorithm could be used as the basis for the implementation of an IT tool for the identification and description of high-tech businesses.

  3. Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion.

    Science.gov (United States)

    Feld, Geoffrey K; El-Etr, Sahar; Corzett, Michele H; Hunter, Mark S; Belhocine, Kamila; Monack, Denise M; Frank, Matthias; Segelke, Brent W; Rasley, Amy

    2014-10-31

    Francisella tularensis is the etiological agent of tularemia, or rabbit fever. Although F. tularensis is a recognized biothreat agent with broad and expanding geographical range, its mechanism of infection and environmental persistence remain poorly understood. Previously, we identified seven F. tularensis proteins that induce a rapid encystment phenotype (REP) in the free-living amoeba, Acanthamoeba castellanii. Encystment is essential to the pathogen's long term intracellular survival in the amoeba. Here, we characterize the cellular and molecular function of REP34, a REP protein with a mass of 34 kDa. A REP34 knock-out strain of F. tularensis has a reduced ability to both induce encystment in A. castellanii and invade human macrophages. We determined the crystal structure of REP34 to 2.05-Å resolution and demonstrate robust carboxypeptidase B-like activity for the enzyme. REP34 is a zinc-containing monomeric protein with close structural homology to the metallocarboxypeptidase family of peptidases. REP34 possesses a novel topology and substrate binding pocket that deviates from the canonical funnelin structure of carboxypeptidases, putatively resulting in a catalytic role for a conserved tyrosine and distinct S1' recognition site. Taken together, these results identify REP34 as an active carboxypeptidase, implicate the enzyme as a potential key F. tularensis effector protein, and may help elucidate a mechanistic understanding of F. tularensis infection of phagocytic cells.

  4. Hi tech microeconomics and information nonintensive calculi

    Directory of Open Access Journals (Sweden)

    Mirko Dohnal

    2013-11-01

    Full Text Available The article establishes link between the contributions made to the study of hi tech phenomena. It analyzes the evolution undergone by studies on the topic of the knowledge economics (HI-TECH process carried out by different disciplines (hard and soft sciences – sociology, ecology etc. from the point of view of the objectives they pursue. The attentions are concentrated on analysis of applicable mathematical tools used to develop realistic formal models. Information intensity is defined as the amount of information which is needed for the realistic application of a corresponding formal tool. High information intensity is desirable because it influences the model accuracy. Low information intensity is preferred when high information intensity requires more information items than are available and this is usually the case in knowledge engineering. Fuzzy models seem to be a useful extension of formal tool used in hi tech microeconomics. However, even fuzzy sets could be prohibitively information intensive. Therefore the range of available formal tools must be considerably broader. This paper introduces qualitative and semiqualitative models and rough sets. Each formal tool is briefly characterized.

  5. Seis nuevas bibliotecas del Banco de la República

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    2000-05-01

    Full Text Available En febrero de 2000, el Banco de la República anunció la decisión de suspender el servicio de tesorería en algunas sucursales y reforzar las áreas culturales, convirtiendo estas últimas en bibliotecas. A partir del 1 de septiembre de 2000 se inicia la adecuación de espacios en las sucursales de Santa Marta, Sincelejo, Valledupar, Florencia y Popayán para albergar en cada una de ellas una biblioteca pública con servicios de lectura para niños y adultos; y en las bibliotecas de Girardot, Honda, Ipiales y Tunja, sucursales que contaban con servicios bibliotecarios a cargo del Banco, se amplían los espacios destinados al servicio de consulta

  6. Madison e Dahl: da república a poliarquia

    OpenAIRE

    José Alexandre Silva Junior; Dalson Britto Figueiredo Filho; Ranulfo Paranhos; Gabriel Augusto Miranda Setti; Willber Nascimento

    2014-01-01

    http://dx.doi.org/10.5007/1806-5023.2014v11n2p42 Qual é a relação entre as teorias política clássica e contemporânea? O principal objetivo desse trabalho é responder a referida questão. Em termos metodológicos, examinam-se alguns conceitos analisados por James Madison e Robert Dahl em perspectiva comparada. Em particular, o foco repousa sobre as noções madisonianas de facção, separação de poderes e república e sobre o conceito de poliarquia proposto por Dahl. Dessa maneira, descrevemos a ...

  7. Automated Production of High Rep Rate Foam Targets

    Science.gov (United States)

    Hall, F.; Spindloe, C.; Haddock, D.; Tolley, M.; Nazarov, W.

    2016-04-01

    Manufacturing low density targets in the numbers needed for high rep rate experiments is highly challenging. This report summarises advances from manual production to semiautomated and the improvements that follow both in terms of production time and target uniformity. The production process is described and shown to be improved by the integration of an xyz robot with dispensing capabilities. Results are obtained from manual and semiautomated production runs and compared. The variance in the foam thickness is reduced significantly which should decrease experimental variation due to target parameters and could allow for whole batches to be characterised by the measurement of a few samples. The work applies to both foil backed and free standing foam targets.

  8. Integral objects and Deligne's category Rep(S_t)

    CERN Document Server

    Del Padrone, Alessio

    2010-01-01

    We give negative answers to certain questions on abelian semisimple tensor categories raised by Bruno Kahn and Charles A. Weibel in connection with the preprint of Kahn "On the multiplicities of a motive" (arXiv:math/0610446), now published as Parts I and IV of "Zeta functions and motives", Pure Appl. Math. Q. 5 (2009), no. 1, part 2, 507-570. For the most interesting examples we used Deligne's category Rep(S_t,F) of representations of the "symmetric group S_t with t not an integer" with F any algebraically closed field of characteristic zero. This is an interesting family of tensor categories, "new" in some sense, interpolating the representations of the symmetric groups. Among other things we give two proofs that this category is not Schur-finite, showing hence explicitly that it is not tensor equivalent to a category of superepresentations of a supergroup.

  9. 3D Image Synthesis for B—Reps Objects

    Institute of Scientific and Technical Information of China (English)

    黄正东; 彭群生; 等

    1991-01-01

    This paper presents a new algorithm for generating 3D images of B-reps objects with trimmed surface boundaries.The 3D image is a discrete voxel-map representation within a Cubic Frame Buffer (CFB).The definition of 3D images for curve,surface and solid object are introduced which imply the connectivity and fidelity requirements.Adaptive Forward Differencing matrix (AFD-matrix) for 1D-3D manifolds in 3D space is developed.By setting rules to update the AFD-matrix,the forward difference direction and stepwise can be adjusted.Finally,an efficient algorithm is presented based on the AFD-matrix concept for converting the object in 3D space to 3D image in 3D discrete space.

  10. 75 FR 27840 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-05-18

    ...: 2010-11842] NUCLEAR REGULATORY COMMISSION [NRC-2010-0080] NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3...: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for General... the existing guidance contained in Supplement 3 to NUREG- 0654/FEMA-REP-1, Rev. 1, ``Criteria...

  11. 75 FR 10524 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-03-08

    ... COMMISSION NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for... document entitled: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action...-4737, or by e-mail to pdr.resource@nrc.gov . NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3,...

  12. STRESS MONITORING OF MULBERRY PLANTS BY FINDING REP USING HYPERSPECTRAL DATA

    Directory of Open Access Journals (Sweden)

    K. Bhosle

    2017-05-01

    Full Text Available Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680–800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  13. Two families of rep-like genes that probably originated by interspecies recombination are represented in viral, plasmid, bacterial, and parasitic protozoan genomes.

    Science.gov (United States)

    Gibbs, Mark J; Smeianov, Vladimir V; Steele, James L; Upcroft, Peter; Efimov, Boris A

    2006-06-01

    Two families of genes related to, and including, rolling circle replication initiator protein (Rep) genes were defined by sequence similarity and by evidence of intergene family recombination. The Rep genes of circoviruses were the best characterized members of the "RecRep1 family." Other members of the RecRep1 family were Rep-like genes found in the genomes of the Canarypox virus, Entamoeba histolytica, and Giardia duodenalis and in a plasmid, p4M, from the Gram-positive bacterium, Bifidobacterium pseudocatenulatum. The "RecRep2 family" comprised some previously identified Rep-like genes from plasmids of phytoplasmas and similar Rep-like genes from the genomes of Lactobacillus acidophilus, Lactococcus lactis, and Phytoplasma asteris. Both RecRep1 and RecRep2 proteins have a nucleotide-binding domain significantly similar to the helicases (2C proteins) of picorna-like viruses. On the N-terminal side of the nucleotide binding domain, RecRep1 proteins have a domain significantly similar to one found in nanovirus Reps, whereas RecRep2 proteins have a domain significantly similar to one in the Reps of pLS1 plasmids. We speculate that RecRep genes have been transferred from viruses or plasmids to parasitic protozoan and bacterial genomes and that Rep proteins were themselves involved in the original recombination events that generated the ancestral RecRep genes.

  14. High Energy Physics Research at Louisiana Tech

    Energy Technology Data Exchange (ETDEWEB)

    Sawyer, Lee [Louisiana State Univ., Baton Rouge, LA (United States); Greenwood, Zeno [Louisiana State Univ., Baton Rouge, LA (United States); Wobisch, Marcus [Louisiana State Univ., Baton Rouge, LA (United States)

    2013-06-28

    The goal of this project was to create, maintain, and strengthen a world-class, nationally and internationally recognized experimental high energy physics group at Louisiana Tech University, focusing on research at the energy frontier of collider-based particle physics, first on the DØ experiment and then with the ATLAS experiment, and providing leadership within the US high energy physics community in the areas of jet physics, top quark and charged Higgs decays involving tau leptons, as well as developing leadership in high performance computing.

  15. AARP iPad Tech to Connect

    CERN Document Server

    Boyd, Barbara

    2012-01-01

    The world is at your fingertips with iPad! AARP iPad: Tech to Connect introduces you to the world?s most popular tablet device, the iPad, and all the amazing things it has to offer. In clear, non-technical language, this book guides you through registering and setting up your iPad, getting acquainted with the multitouch interface, navigating around the screen, finding and downloading apps, reading books, listening to music, watching videos, surfing the web, and communicating with friends and family. Developed in partnership with AARP and dedicated to helping readers stay connected with friends

  16. FinTech Market Development Perspectives

    OpenAIRE

    Kalmykova Ekaterina; Ryabova Anna

    2016-01-01

    Fast development of technologies has led to emergence of the new market – FinTech – which is very attractive for investors today. By now this market has a great number of different concepts: P2P-crediting, E-wallets, Bitcoins, mPOS-acquiring, T-commerce, mobile banks, etc. Many of these tools have already heavily entered our ordinary life. People can obtain any credits through special services on the Internet from other users without participation of banks, pay by credit card using mobile dev...

  17. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.

    Directory of Open Access Journals (Sweden)

    Jorge Mansilla-Soto

    2009-07-01

    Full Text Available Rep68 is a multifunctional protein of the adeno-associated virus (AAV, a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome 19. Rep68 is a member of the superfamily 3 (SF3 helicases, along with the well-studied initiator proteins simian virus 40 large T antigen (SV40-LTag and bovine papillomavirus (BPV E1. Structurally, SF3 helicases share two domains, a DNA origin interaction domain (OID and an AAA(+ motor domain. The AAA(+ motor domain is also a structural feature of cellular initiators and it functions as a platform for initiator oligomerization. Here, we studied Rep68 oligomerization in vitro in the presence of different DNA substrates using a variety of biophysical techniques and cryo-EM. We found that a dsDNA region of the AAV origin promotes the formation of a complex containing five Rep68 subunits. Interestingly, non-specific ssDNA promotes the formation of a double-ring Rep68, a known structure formed by the LTag and E1 initiator proteins. The Rep68 ring symmetry is 8-fold, thus differing from the hexameric rings formed by the other SF3 helicases. However, similiar to LTag and E1, Rep68 rings are oriented head-to-head, suggesting that DNA unwinding by the complex proceeds bidirectionally. This novel Rep68 quaternary structure requires both the DNA binding and AAA(+ domains, indicating cooperativity between these regions during oligomerization in vitro. Our study clearly demonstrates that Rep68 can oligomerize through two distinct oligomerization pathways, which depend on both the DNA structure and cooperativity of Rep68 domains. These findings provide insight into the dynamics and oligomeric adaptability of Rep68 and serve as a step towards understanding the role of this multifunctional protein during AAV DNA replication and site-specific integration.

  18. TechTrends 2010-2015: A Content Analysis

    Science.gov (United States)

    Stauffer, Eric

    2017-01-01

    This study is a content analysis of articles published within the journal "TechTrends" from 2000 to 2015. The study reveals that the publication "TechTrends" has increased the overall number of peer reviewed original papers over the last 6 years. The author describes the proportion of these original papers per volume and…

  19. Georgia tech catalog of gravitational waveforms

    Science.gov (United States)

    Jani, Karan; Healy, James; Clark, James A.; London, Lionel; Laguna, Pablo; Shoemaker, Deirdre

    2016-10-01

    This paper introduces a catalog of gravitational waveforms from the bank of simulations by the numerical relativity effort at Georgia Tech. Currently, the catalog consists of 452 distinct waveforms from more than 600 binary black hole simulations: 128 of the waveforms are from binaries with black hole spins aligned with the orbital angular momentum, and 324 are from precessing binary black hole systems. The waveforms from binaries with non-spinning black holes have mass-ratios q = m 1/m 2 ≤ 15, and those with precessing, spinning black holes have q ≤ 8. The waveforms expand a moderate number of orbits in the late inspiral, the burst during coalescence, and the ring-down of the final black hole. Examples of waveforms in the catalog matched against the widely used approximate models are presented. In addition, predictions of the mass and spin of the final black hole by phenomenological fits are tested against the results from the simulation bank. The role of the catalog in interpreting the GW150914 event and future massive binary black-hole search in LIGO is discussed. The Georgia Tech catalog is publicly available at einstein.gatech.edu/catalog.

  20. Madison e Dahl: da república a poliarquia

    Directory of Open Access Journals (Sweden)

    José Alexandre Silva Junior

    2014-12-01

    Full Text Available http://dx.doi.org/10.5007/1806-5023.2014v11n2p42 Qual é a relação entre as teorias política clássica e contemporânea? O principal objetivo desse trabalho é responder a referida questão. Em termos metodológicos, examinam-se alguns conceitos analisados por James Madison e Robert Dahl em perspectiva comparada. Em particular, o foco repousa sobre as noções madisonianas de facção, separação de poderes e república e sobre o conceito de poliarquia proposto por Dahl. Dessa maneira, descrevemos a continua influência de certos aspectos próprios da teoria política clássica no modo como a teoria contemporânea lida com o tema. Concluímos que a contribuição dos autores clássicos permite que a teoria política contemporânea seja capaz de tentar oferecer explicações mais robustas aos “novos” problemas enfrentados pela disciplina.

  1. Paradoxo e natureza no livro V da República

    Directory of Open Access Journals (Sweden)

    Marcelo P. Marques

    2010-12-01

    Full Text Available O artigo analisa a primeira onda do livro V da República de Platão, levando em conta a oposição entre opinião (dóxa e ciência (epistéme, só formulada ao final da terceira onda. Sócrates problematiza a opinião corrente que aceita a diferença de natureza entre homens e mulheres para avançar a ideia de uma natureza humana comum. É essa tese paradoxal que justifica que possam ter uma mesma educação e que, assim, possam desempenhar as mesmas funções, vindo a ser guardiões e governantes da cidade.The paper analyses the first wave in Plato´s Republic V, taking into account the opposition between opinion (doxa and science (episteme, formulated at the end of the third wave. Socrates questions the current opinion which accepts the difference in nature between men and women in order to propose the idea of a common human nature. It is this paradoxical thesis that justifies the proposal that all should have the same education, thus allowing them to fulfill the same functions and, eventually, to become guardians and rulers in the city.

  2. China - 60 anos de República Popular

    Directory of Open Access Journals (Sweden)

    Wladimir Pomar

    2009-10-01

    Full Text Available Em dezembro de 1949, após mais de 23 anos de guerras, tanto civis, quanto de resistência contra a agressão japonesa, a China assistiu à fundação da República Popular, com a vitória do Exército Popular de Libertação, tendo à frente o Partido Comunista, sobre os exércitos comandados pelo Guomindang.

  3. Euclides da Cunha e a República

    Directory of Open Access Journals (Sweden)

    Roberto Ventura

    1996-04-01

    Full Text Available A revisão da República é central na obra de Euclides da Cunha, presente em seus artigos de jornal e na maior parte de seus livros. Analisou o regime republicano não só em Os sertões (1902, em que tratou da guerra de Canudos, como em Contrastes e confrontos (1907 e em Á margem da história (1909. Foi testemunha e intérprete dos rumos do novo regime, que ajudara a fundar com artigos de propaganda política no jornal A Província de S. Paulo.The revision of the Republic is a central concern in the works of Euclides da Cunha. It appears in his newspaper articles and in most of his books. He analysed the republican regime not only in Os sertões (Rebellion in the backlands, 1902, in which he deals with the Canudos War, but also in Contrastes e confrontos (1907 and in À margem da história (1909. He both witnessed and interpreted the trends of the new regime which he had helped to set up with his political articles in the newspaper A Província de S. Paulo.

  4. TechEdSat Nano-Satellite Series Fact Sheet

    Science.gov (United States)

    Murbach, Marcus; Martinez, Andres; Guarneros Luna, Ali

    2014-01-01

    TechEdSat-3p is the second generation in the TechEdSat-X series. The TechEdSat Series uses the CubeSat standards established by the California Polytechnic State University Cal Poly), San Luis Obispo. With typical blocks being constructed from 1-unit (1U 10x10x10 cm) increments, the TechEdSat-3p has a 3U volume with a 30 cm length. The project uniquely pairs advanced university students with NASA researchers in a rapid design-to-flight experience lasting 1-2 semesters.The TechEdSat Nano-Satellite Series provides a rapid platform for testing technologies for future NASA Earth and planetary missions, as well as providing students with an early exposure to flight hardware development and management.

  5. Hariduspoliitikas ilmnevad üksmeele märgid / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 7. juuni lk. 2, Nädaline 10. juuni lk. 2. Haridusminister Mailis Reps Res Publica ja Isamaaliidu ühisest haridusprogrammist ning juba teostumas hariduspoliitilistest eesmärkidest

  6. Reps sai Narvas tõrjuva vastuvõtu osaliseks / Tanel Mazur

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2005-01-01

    Selle aasta koolirahu kuulutati välja Narva linnuses, rongkäigus osalesid Narva koolide õpilaste hulgas ka üle 1300 teistest piirkondadest saabunud õpilase. Tervituskõnega esines haridus- ja teadusminister Mailis Reps

  7. The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

    NARCIS (Netherlands)

    Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

    2009-01-01

    Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway. U

  8. The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

    NARCIS (Netherlands)

    Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

    2009-01-01

    Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway. U

  9. Comparison of a commercially available rep-PCR system (Diversilab(R)) with PCR-ribotyping for typing of Clostridium difficile strains.

    OpenAIRE

    Eckert, C.; van Broeck, Johan; Spigaglia, P.; Burghoffer, B; Delmée, Michel; Mastrantonio, P; Barbut, F

    2011-01-01

    This study compared a rep-PCR method (DiversiLab® system) to PCR-ribotyping. The discriminatory power of rep-PCR was 0.997. Among the PCR-ribotype 027, different rep-types could be distinguished. Rep-PCR showed a higher discriminatory power than PCR-ribotyping. Nevertheless, this method requires technical skill and visual interpretation of rep-PCR fingerprint patterns may be difficult.

  10. Supplier challenges in health tech innovation

    DEFF Research Database (Denmark)

    Rolfstam, Max

    Suppliers, in particular small innovative firms, is an important contributor not only for innovation in health-tech, but also a component to consider in the light of the emerging policy interest for using public procurement as a means to stimulate innovation. Research on barriers preventing...... these firms from providing innovations to public health authorities is therefore easily justified. Although substantive knowledge already prevails on the topic, it appears to be a lack in the literature concerning small innovative firms. To help to overcome this gap the paper discusses preliminary case study...... findings collected in the context of the Baltic Sea Health Region HealthPort project. The overall aim with the project was to facilitate ‘business acceleration’ by providing support, training and bridging innovative SMEs and health care organisations ultimately to strengthen the Baltic Sea Region health...

  11. Metal-Induced Stabilization and Activation of Plasmid Replication Initiator RepB

    Science.gov (United States)

    Ruiz-Masó, José A.; Bordanaba-Ruiseco, Lorena; Sanz, Marta; Menéndez, Margarita; del Solar, Gloria

    2016-01-01

    Initiation of plasmid rolling circle replication (RCR) is catalyzed by a plasmid-encoded Rep protein that performs a Tyr- and metal-dependent site-specific cleavage of one DNA strand within the double-strand origin (dso) of replication. The crystal structure of RepB, the initiator protein of the streptococcal plasmid pMV158, constitutes the first example of a Rep protein structure from RCR plasmids. It forms a toroidal homohexameric ring where each RepB protomer consists of two domains: the C-terminal domain involved in oligomerization and the N-terminal domain containing the DNA-binding and endonuclease activities. Binding of Mn2+ to the active site is essential for the catalytic activity of RepB. In this work, we have studied the effects of metal binding on the structure and thermostability of full-length hexameric RepB and each of its separate domains by using different biophysical approaches. The analysis of the temperature-induced changes in RepB shows that the first thermal transition, which occurs at a range of temperatures physiologically relevant for the pMV158 pneumococcal host, represents an irreversible conformational change that affects the secondary and tertiary structure of the protein, which becomes prone to self-associate. This transition, which is also shown to result in loss of DNA binding capacity and catalytic activity of RepB, is confined to its N-terminal domain. Mn2+ protects the protein from undergoing this detrimental conformational change and the observed protection correlates well with the high-affinity binding of the cation to the active site, as substituting one of the metal-ligands at this site impairs both the protein affinity for Mn2+and the Mn2+-driven thermostabilization effect. The level of catalytic activity of the protein, especially in the case of full-length RepB, cannot be explained based only on the high-affinity binding of Mn2+ at the active site and suggests the existence of additional, lower-affinity metal binding site

  12. A Dimeric Rep Protein Initiates Replication of a Linear Archaeal Virus Genome: Implications for the Rep Mechanism and Viral Replication ▿ †

    Science.gov (United States)

    Oke, Muse; Kerou, Melina; Liu, Huanting; Peng, Xu; Garrett, Roger A.; Prangishvili, David; Naismith, James H.; White, Malcolm F.

    2011-01-01

    The Rudiviridae are a family of rod-shaped archaeal viruses with covalently closed, linear double-stranded DNA (dsDNA) genomes. Their replication mechanisms remain obscure, although parallels have been drawn to the Poxviridae and other large cytoplasmic eukaryotic viruses. Here we report that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. We show that SIRV Rep nicks the viral hairpin terminus, forming a covalent adduct between an active-site tyrosine and the 5′ end of the DNA, releasing a 3′ DNA end as a primer for DNA synthesis. The enzyme can also catalyze the joining reaction that is necessary to reseal the DNA hairpin and terminate replication. The dimeric structure points to a simple mechanism through which two closely positioned active sites, each with a single tyrosine residue, work in tandem to catalyze DNA nicking and joining. We propose a novel mechanism for rudivirus DNA replication, incorporating the first known example of a Rep protein that is not linked to RCR. The implications for Rep protein function and viral replication are discussed. PMID:21068244

  13. Rep-PCR--a variant to RAPD or an independent technique of bacteria genotyping? A comparison of the typing properties of rep-PCR with other recognised methods of genotyping of microorganisms.

    Science.gov (United States)

    Baldy-Chudzik, K

    2001-01-01

    The paper presents technical aspects of rep-PCR fingerprinting technique and compares its typing abilities, differentiation power and reproducibility with other recognised and recommended genotyping methods. Although rep-PCR fingerprinting is similar to MAAP techniques, it demonstrates some essentially different elements. The data presented in this review, indicate a rep-PCR genomic fingerprinting technique as a highly discriminating, independent screening method for determining the taxonomical diversity of bacterial population.

  14. FinTech – What's in a Name?

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    FinTech, the word which originates from marriage of “finance” and “technology”, designates currently a novel, innovative and emerging field which attracts attention from the publicity. At the moment there is no universal understanding and definition of FinTech in the research, however, the topic is widely addressed by the English- and German-speaking press. In this study we aim to make insights into how the press and other popular media understand and frame FinTech, discussing definitions tha...

  15. Fee-based services in sci-tech libraries

    CERN Document Server

    Mount, Ellis

    2013-01-01

    This timely and important book explores how fee-based services have developed in various types of sci-tech libraries. The authoritative contributors focus on the current changing financial aspects of the sci-tech library operation and clarify for the reader how these changes have brought about conditions in which traditional methods of funding are no longer adequate. What new options are open and how they are best being applied in today's sci-tech libraries is fully and clearly explained and illustrated. Topics explored include cost allocation and cost recovery, fees for computer searching, an

  16. An analisys of consumers’ expenditures on high-tech products

    Directory of Open Access Journals (Sweden)

    Dovleac, L.

    2011-01-01

    Full Text Available High – tech products are gradually adopted by consumers, who become to consider them indispensable. Their acquisition requires each time a pretty significant financial investment and a serious decision with a high perceived risk. In this paper we intend to analyse some financial issues related to high-tech products purchased by consumers from Brasov city in 2009, such as: the amount of money spent on high tech products, the financial sources used, the connections between expenditures and consumer’s characteristics.

  17. China's High-tech Exports: Myth and Reality

    OpenAIRE

    Xing, Yuqing

    2011-01-01

    China’s leading position in high-tech exports is a myth created by outdated trade statistics, which are inconsistent with the trade based on global supply chains. Assembled high-tech products, made with imported key parts and components, accounted for 82% of China’s high-tech exports. Current trade statistics mistakenly credit entire values of these assembled products to China, thus greatly inflate the export value. For instance, in 2009 China’s export in the iPhone amounted US$4.6 billion, o...

  18. FinTech – What's in a Name?

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    FinTech, the word which originates from marriage of “finance” and “technology”, designates currently a novel, innovative and emerging field which attracts attention from the publicity. At the moment there is no universal understanding and definition of FinTech in the research, however, the topic is widely addressed by the English- and German-speaking press. In this study we aim to make insights into how the press and other popular media understand and frame FinTech, discussing definitions tha...

  19. provincia de Buenos Aires (República Argentina

    Directory of Open Access Journals (Sweden)

    Rubén Alberto Cervini

    2008-01-01

    Full Text Available En el estudio que se informa se investigaron las relaciones entre progreso de aprendizaje (valor agregado, motivación y autoconcepto académico del alumno en Matemática, en el marco de los efectos de las características socioeconómicas y académicas del alumno y de su escuela. Para la medición del valor agregado se utilizaron los resultados de dos pruebas estandarizadas de Matemática aplicadas a una cohorte de alumnos de la Provincia de Buenos Aires (República Argentina en dos momentos diferentes (séptimo y noveno años de Educación General Bási ca - EGB. Las mediciones de motivación y de autoconcepto se basaron en respuestas a ítemes binarios de actitudes con respecto a Ma temática y fueron definidas utilizando el análisis de la componente prin - cipal, a partir de la matriz de correlación tetracórica (método heurístico. Para el análisis de las correlaciones se utilizó la téc nica estadística de modelos multinivel. El presente estudio relaciona los resultados empíricos con la teoría del habitus de Bourdieu. Inicialmente, el autoconcepto resulta significativa y positivamente asociado con el puntaje en la prueba y con el progreso de aprendizaje posterior. Este efecto continúa siendo significati vo aun cuando se controlan los efectos del nivel socioeconómi - co y del género del alumno. Sin embargo, su capacidad ex plicativa es muy tenue desde el punto de vista práctico. Si bien este resultado confirmaría la hipótesis central de la teoría de la reproducción, indica un sendero a través del cual podrían producirse transformaciones. Uno de los desafíos del sistema educativo es promover el habitus escolar cultivado (autoconcepto más allá de las determinaciones sociales, culturales y económicas.

  20. Virginia Tech, Sweet Briar College formalize student exchange program

    OpenAIRE

    Owczarski, Mark

    2006-01-01

    Virginia Tech and Sweet Briar College have formalized a student exchange program that will broaden the education opportunities of students, provide a diverse campus environment, and facilitate cooperation and collaboration among student and faculty at each institution.

  1. Lavender Commencement Ceremony to honor LGBT graduates at Virginia Tech

    OpenAIRE

    Shannon, Kelly Baker

    2010-01-01

    The Lesbian, Gay, Bisexual, and Transgender (LGBT) Caucus at Virginia Tech is sponsoring the Second Annual Lavender Commencement Ceremony, which will be held on May 13 at 11 a.m. in the Old Dominion Ballroom of Squires Student Center.

  2. Events Scheduled for Virginia Tech's Black History Month

    OpenAIRE

    Felker, Susan B.

    2004-01-01

    A variety of lectures, discussions, performances and displays will be held during Virginia Tech's observance of Black History Month. Events begin Jan. 19 and run through Feb. 28 and are free an open to the public (except where noted).

  3. The Trail Inventory of Bayou Teche NWR [Cycle 2

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to create a baseline inventory of all non-motorized trails on Bayou Teche National Wildlife Refuge. Trails in this inventory are...

  4. Virginia Tech Horse Judging Team leaves its mark in Texas

    OpenAIRE

    Greiner, Lori A.

    2010-01-01

    The Virginia Tech Horse Judging Team completed a successful spring competition season with a win at the American Paint Horse Association's Spring Intercollegiate Horse Judging Sweepstakes in Fort Worth, Texas.

  5. Virginia Tech remains among best values in public higher education

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Virginia Tech is again ranked among the top public colleges and universities in the nation that offer a high quality educational experience at an affordable price, according to "Kiplinger's Personal Finance" magazine.

  6. Virginia Tech recognized for world-class food science program

    OpenAIRE

    Sutphin, Michael D.

    2010-01-01

    The Institute of Food Technologists (IFT) has reaccredited the undergraduate curriculum of Virginia Tech's Department of Food Science and Technology, reaffirming the department's place as a leader in contributing to food quality, safety, marketability, and availability.

  7. Virginia Tech's Cook Counseling Center receives international counseling accreditation

    OpenAIRE

    DeLauder, Rachel

    2010-01-01

    The Virginia Tech Thomas E. Cook Counseling Center has been accredited by the International Association of Counseling Services, Inc., an organization of United States, Canadian, and Australian counseling agencies based in Alexandria, Va.

  8. Bayou Teche National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Bayou Teche NWR for the next 15 years. This plan outlines the Refuge vision and purpose...

  9. Bayou Teche National Wildlife Refuges Habitat Management Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Bayou Teche NWR Habitat Management Plan provides a long-term vision and specific guidance on managing habitats for the resources of concern at Bayou Sauvage NWR,...

  10. rep-PCR-Mediated Genomic Fingerprinting: A Rapid and Effective Method to Identify Clavibacter michiganensis.

    Science.gov (United States)

    Louws, F J; Bell, J; Medina-Mora, C M; Smart, C D; Opgenorth, D; Ishimaru, C A; Hausbeck, M K; de Bruijn, F J; Fulbright, D W

    1998-08-01

    ABSTRACT The genomic DNA fingerprinting technique known as repetitive-sequence-based polymerase chain reaction (rep-PCR) was evaluated as a tool to differentiate subspecies of Clavibacter michiganensis, with special emphasis on C. michiganensis subsp. michiganensis, the pathogen responsible for bacterial canker of tomato. DNA primers (REP, ERIC, and BOX), corresponding to conserved repetitive element motifs in the genomes of diverse bacterial species, were used to generate genomic fingerprints of C. michiganensis subsp. michiganensis, C. michiganensis subsp. sepedonicus, C. michiganensis subsp. nebraskensis, C. michiganensis subsp. tessellarius, and C. michiganensis subsp. insidiosum. The rep-PCR-generated patterns of DNA fragments observed after agarose gel electrophoresis support the current division of C. michiganensis into five subspecies. In addition, the rep-PCR fingerprints identified at least four types (A, B, C, and D) within C. michiganensis subsp. michiganensis based on limited DNA polymorphisms; the ability to differentiate individual strains may be of potential use in studies on the epidemiology and host-pathogen interactions of this organism. In addition, we have recovered from diseased tomato plants a relatively large number of naturally occurring avirulent C. michiganensis subsp. michiganensis strains with rep-PCR fingerprints identical to those of virulent C. michiganensis subsp. michiganensis strains.

  11. The oligomeric Rep protein of Mungbean yellow mosaic India virus (MYMIV) is a likely replicative helicase.

    Science.gov (United States)

    Choudhury, Nirupam Roy; Malik, Punjab Singh; Singh, Dharmendra Kumar; Islam, Mohammad Nurul; Kaliappan, Kosalai; Mukherjee, Sunil Kumar

    2006-01-01

    Geminiviruses replicate by rolling circle mode of replication (RCR) and the viral Rep protein initiates RCR by the site-specific nicking at a conserved nonamer (TAATATT downward arrow AC) sequence. The mechanism of subsequent steps of the replication process, e.g. helicase activity to drive fork-elongation, etc. has largely remained obscure. Here we show that Rep of a geminivirus, namely, Mungbean yellow mosaic India virus (MYMIV), acts as a replicative helicase. The Rep-helicase, requiring > or =6 nt space for its efficient activity, translocates in the 3'-->5' direction, and the presence of forked junction in the substrate does not influence the activity to any great extent. Rep forms a large oligomeric complex and the helicase activity is dependent on the oligomeric conformation ( approximately 24mer). The role of Rep as a replicative helicase has been demonstrated through ex vivo studies in Saccharomyces cerevisiae and in planta analyses in Nicotiana tabacum. We also establish that such helicase activity is not confined to the MYMIV system alone, but is also true with at least two other begomoviruses, viz., Mungbean yellow mosaic virus (MYMV) and Indian cassava mosaic virus (ICMV).

  12. Pricing Policy and Strategies for Consumer High-Tech Products

    Directory of Open Access Journals (Sweden)

    Dovleac, L.

    2014-06-01

    Full Text Available This paper highlights the complex process of price setting for consumer high-tech products. These prices are highly influenced by some external factors from the economic and social environment. The main objective of this paper is to establish the most effective pricing policies and strategies used by high-tech companies of various sizes. Decisions about price fixing for consumer high-technology products are largely influenced by consumer behaviour, too.

  13. Overseas Tech Firms Ramp Up Hiring In Silicon Valley

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Fpr years, U.S.high-tech executives have fretted about the loss of technology jobs to countries such as China and India.But there is a countervailing force: Foreign companies are leaning heavily on engineers they hire in Silicon Valley. Companies from Europe and Asia increasingly are using high-tech teams in the Bay Area to conduct long-range research and help design cutting-edge products for global markets.

  14. Virginia Tech creates Caribbean center for education and research

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    Virginia Tech has established a research, education, and outreach center in the Caribbean that will serve as part of a broad strategy to create international centers of scholarship around the world. The Caribbean Center for Education and Research (CCER) in Punta Cana, on the eastern tip of the Dominican Republic, will allow Virginia Tech faculty to conduct research as well as instruct students on biodiversity, environmental and social sustainability, global issues in natural resources, and ho...

  15. Slow Tech: The Bridge between Computer Ethics and Business Ethics

    OpenAIRE

    Patrignani, Norberto; Whitehouse, Diane

    2014-01-01

    Part 1: Society, Social Responsibility, Ethics and ICT; International audience; This paper addresses the difficult task of implementing the concept of Slow Tech, that is, information and communication technology (ICT) that is good, clean and fair, in a business environment. It investigates the democratic, environmental, and social challenges currently facing ICT vendors. More specifically, it examines the opportunities available for these companies to use Slow Tech as a bridging mechanism bet...

  16. Promoting High-tech Industrialization through Mechanism Innovation

    Institute of Scientific and Technical Information of China (English)

    Guo Haiyan; Zhao Baohua

    2002-01-01

    @@ With the further implementation of the knowledge innovation program (KIP), piloted by the Chinese Academy of Sciences (CAS), encouraging progress has been made in contributing to the development of the country's high-tech industry, and forging S&T cooperation with local governments and industrial sectors. This was revealed at the Second CAS Conference on High-tech Industrialization April 25 - 29 in Shenzhen, Guangdong Province.

  17. Allina Health System's approach to high tech and high touch.

    Science.gov (United States)

    Tam, T A

    1997-01-01

    All health care providers, regardless of their integration status, must meet customer expectations to maintain market share and viability. The balance between high tech and high touch customer interactions is not a fad or trend. For integrated health systems with the full continuum of medical care, additional challenges are presented by the organization's competing health care delivery and financing components. Allina Health System describes its integrated health system approach to satisfying customer high tech and high touch needs.

  18. FinTech Market Development Perspectives

    Directory of Open Access Journals (Sweden)

    Kalmykova Ekaterina

    2016-01-01

    Full Text Available Fast development of technologies has led to emergence of the new market – FinTech – which is very attractive for investors today. By now this market has a great number of different concepts: P2P-crediting, E-wallets, Bitcoins, mPOS-acquiring, T-commerce, mobile banks, etc. Many of these tools have already heavily entered our ordinary life. People can obtain any credits through special services on the Internet from other users without participation of banks, pay by credit card using mobile devices, and get information about expenses and incomes according to the card anywhere in the world. Users do not need to go to banks anymore and to spend their time for credit arrangements, currency exchange, to look for ATMs to remove cash. Purchases on the Internet can be paid not only in rubles, but also in new digital currency. These tools make life easier, however, they pose a serious threat for banks. Now, bank institutions should create more convenient and utility services for the clients to keep clients. Therefore, bank and credit systems start to change actively.

  19. Georgia Tech Catalog of Gravitational Waveforms

    CERN Document Server

    Jani, Karan; Clark, James A; London, Lionel; Laguna, Pablo; Shoemaker, Deirdre

    2016-01-01

    This paper introduces a catalog of gravitational waveforms from the bank of simulations by the numerical relativity effort at Georgia Tech. Currently, the catalog consists of 452 distinct waveforms from more than 600 binary black hole simulations: 128 of the waveforms are from binaries with black hole spins aligned with the orbital angular momentum, and 324 are from precessing binary black hole systems. The waveforms from binaries with non-spinning black holes have mass-ratios $q = m_1/m_2 \\le 15$, and those with precessing, spinning black holes have $q \\le 8$. The waveforms expand a moderate number of orbits in the late inspiral, the burst during coalescence, and the ring-down of the final black hole. Examples of waveforms in the catalog matched against the widely used approximate models are presented. In addition, predictions of the mass and spin of the final black hole by phenomenological fits are tested against the results from the simulation bank. The role of the catalog in interpreting the GW150914 even...

  20. Radioisotope Electric Propulsion (REP): A Near-Term Approach to Nuclear Propulsion

    Science.gov (United States)

    Schmidt, George R.; Manzella, David H.; Kamhawi, Hani; Kremic, Tibor; Oleson, Steven R.; Dankanich, John W.; Dudzinski, Leonard A.

    2009-01-01

    Studies over the last decade have shown radioisotope-based nuclear electric propulsion to be enhancing and, in some cases, enabling for many potential robotic science missions. Also known as radioisotope electric propulsion (REP), the technology offers the performance advantages of traditional reactor-powered electric propulsion (i.e., high specific impulse propulsion at large distances from the Sun), but with much smaller, affordable spacecraft. Future use of REP requires development of radioisotope power sources with system specific powers well above that of current systems. The US Department of Energy and NASA have developed an advanced Stirling radioisotope generator (ASRG) engineering unit, which was subjected to rigorous flight qualification-level tests in 2008, and began extended lifetime testing later that year. This advancement, along with recent work on small ion thrusters and life extension technology for Hall thrusters, could enable missions using REP sometime during the next decade.

  1. Spreading the Eco-Message: Using Proactive Coping to Aid Eco-Rep Behavior Change Programming

    Directory of Open Access Journals (Sweden)

    Matthew J. Zawadzki

    2013-04-01

    Full Text Available Making pro-environmental behavior changes can be difficult, particularly when these changes challenge daily routines and comfortable lifestyles. We designed and implemented an eco-representative intervention program to help students reduce their energy use by proactively coping with barriers to pro-environmental behavior change, and then communicate effective behavior change strategies to student peers. Twenty-nine first-year college students participated in a four-week proactive coping training to change five environmentally impactful behaviors and then spread behavior change messages to fellow residents during a two-week energy challenge. Eco-reps successfully changed their own behaviors in a pro-environmental direction by generating important barriers and successful facilitators for behavior change, and eco-rep residence halls were more likely to reduce energy and maintain reductions compared to non-eco-rep halls. Implications for future environmental behavior change interventions are discussed.

  2. DIMENSION VARIATION OF FEATURE-BASED MODEL BY OPERATING DIRECTLY ON B-REP

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    A new algorithm for dimension variation of feature-based models is developed.The algorithm is based on B-Rep/CSG hybrid scheme and operates directly on B-Rep.Product information (including the features locating dimensions and other data for manufacture) will not lose after model variation and modification.Furthermore, the definition and solution of features constraints are also supported.The scheme of directly operating on B-Rep overcomes many drawbacks of other proposed methods, most of which need to redo all of the previous work to implement dimension variation, so the computational cost is expensive and product information will lose.What is presented in this paper makes a new way in the area of parametric design.

  3. Iterest grows for Dutch mid-tech and low-tech greenhouse technology : A greenhouse to suit all tropical conditions (interview with Anne Elings)

    NARCIS (Netherlands)

    Kierkels, T.; Elings, A.

    2014-01-01

    The Netherlands sets the standard for high-tech greenhouses worldwide. But increasingly suppliers are looking too at possibilities within the mid-tech and even the low-tech market segments. The Dutch government is supporting demonstration projects, for example in Mexico, East Africa and Malaysia. Te

  4. Recuperar la història de la Segona República Espanyola

    OpenAIRE

    Fontana, Josep, 1931-

    2003-01-01

    L'article recull un discurs de Josep Fontana pronunciat l'octubre de 2002 a la Universitat Autònoma de Barcelona on reflexiona entorn la necessitat de formular una nova lectura història de la Segona República espanyola, de la guerra civil i del franquisme. El artículo recoge un discurso de Josep Fontana pronunciado en octubre del 2002 en la Universitat Autònoma de Barcelona donde reflexiona acerca de la necesidad de formular una nueva lectura de la historia de la Segunda República española...

  5. Design of a Battery Intermediate Storage System for Rep-Rated Pulsed Power Loads

    Science.gov (United States)

    2013-04-01

    Abstract—The U.S. Naval Research Laboratory (NRL) is developing a battery-powered, rep-rate charger for a 60-kJ capacitor bank . The capacitor ...developing a rapid charger for a 60-kJ capacitor bank capable of charging a 4800- µF capacitor to 5-kV in roughly five seconds. This system needs to...U.S. Naval Research Laboratory (NRL) is developing a battery-powered, rep-rate charger for a 60-kJ capacitor bank . The capacitor will be charged with

  6. El derecho del trabajo democrático en la República de Weimar

    OpenAIRE

    Gil Albuerquerque, Román de la Trinidad

    2016-01-01

    La tesis "El Derecho del Trabajo democrático en la República de Weimar" es, de una parte, una introducción contextualizadora a la historia político-social, sindical, del Derecho del Trabajo y de la obra de significados juristas demócratas comprometidos con el nacimiento de la nueva disciplina jurídica (y en parte responsables de su constitucionalización) y con su desarrollo en la República de Weimar, así como una consideración transversal y comparativa de varias instituciones fundamentales p...

  7. El derecho del trabajo democrático en la República de Weimar

    OpenAIRE

    Gil Albuerquerque, Román de la Trinidad

    2016-01-01

    La tesis "El Derecho del Trabajo democrático en la República de Weimar" es, de una parte, una introducción contextualizadora a la historia político-social, sindical, del Derecho del Trabajo y de la obra de significados juristas demócratas comprometidos con el nacimiento de la nueva disciplina jurídica (y en parte responsables de su constitucionalización) y con su desarrollo en la República de Weimar, así como una consideración transversal y comparativa de varias instituciones fundamentales p...

  8. Fuzzy model investic do High-tech projektů

    Directory of Open Access Journals (Sweden)

    Alžběta Kubíčková

    2013-10-01

    Full Text Available Purpose of the article: Relations among parameters of High-tech projects are very complex, vague, partially inconsistent and multidimensional. Optimal decisions to invest into High-tech companies require top field experts and knowledgeable investors. Therefore the conventional methods of investments analysis are not relevant. Therefore fuzzy logic is introduced. Methodology/methods: A fuzzy knowledge base is a flexible framework for acquisition of vague inconsistent knowledge items which are typical for knowledge economics and consequently for High-tech projects. The pooling of the records and / or observations represents a trade-off between minimal modification of the original data and elimination of inconsistencies among available sets of data. Scientific aim: The paper presents a detailed description of fuzzy model of investment decision making into High-tech firm’s projects. A set of conditional statements was used to formalize the effects of selected variables on investment feasibility of High-tech projects. The main aim is to quantify feasibilities of High-tech projects risk investors make good /not bad decisions. Findings: A set of 50 observations of High-tech companies was transformed into a set of 50 conditional statements using 14 variables. The result is the fuzzy model, which can be used to answer investors’ queries. Two queries are answered and presented in details as an example and as a nucleus of a fuzzy dialogue investor – computer. Conclusions: The main problem is the sparseness of the fuzzy model. Many fuzzy similarities are relatively low and the decision process is therefore often problematic. A much more complex set of variables must be applied to specify the fuzzy model to increase reliability of predictions and decisions.

  9. Determination of genetic differences between fluid and nonfluid variants of Clavibacter michiganensis subsp. sepedonicus using rep-PCR technique.

    Science.gov (United States)

    Fousek, J; Mráz, I

    2003-01-01

    Testing of 23 isolates of Clavibacter michiganensis subsp. sepedonicus for analysis by rep-PCR (using BOX, ERIC, REP primer sets) was used for the purpose of localization of genetic markers for fluid and/or nonfluid strains. None of the primer sets was successful in detecting genetic differences between the isolates and no polymorphism was generated.

  10. 75 FR 32493 - NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-06-08

    ... SECURITY Federal Emergency Management Agency NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for... be held to discuss the proposed Supplement 3 to NUREG-0654/FEMA-REP-1, Rev.1, Guidance for Protective Action Recommendations for General Emergencies (NUREG Supp 3). NUREG Supp 3 addresses onsite and...

  11. RiskREP: Risk-Based Security Requirements Elicitation and Prioritization (extended version)

    NARCIS (Netherlands)

    Herrmann, Andrea; Morali, A.

    2010-01-01

    Today, companies are required to be in control of the security of their IT assets. This is especially challenging in the presence of limited budgets and conflicting requirements. Here, we present Risk-Based Requirements Elicitation and Prioritization (RiskREP), a method for managing IT security

  12. Overview of RepLab 2014: Author Profiling and Reputation Dimensions for Online Reputation Management

    NARCIS (Netherlands)

    Amigó, E.; Carrillo-de-Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.; Spina, D.

    2014-01-01

    This paper describes the organisation and results of RepLab 2014, the third competitive evaluation campaign for Online Reputation Management systems. This year the focus lied on two new tasks: reputation dimensions classification and author profiling, which complement the aspects of reputation

  13. Romanos e Partos: atividades bélicas na República e no Principado

    OpenAIRE

    Ana Teresa Marques Gonçalves

    2005-01-01

    O objetivo deste artigo é analisar algumas das várias batalhas travadas entre romanos e partos ao longo da República e do Principado, utilizando para tanto as obras de Plutarco, Dion Cássio, Herodiano, Polieno, Eutrópio, Aurélio Victor e Zózimo.

  14. RePS: a sequence assembler that masks exact repeats identified from the shotgun data

    DEFF Research Database (Denmark)

    Wang, Jun; Wong, Gane Ka-Shu; Ni, Peixiang;

    2002-01-01

    We describe a sequence assembler, RePS (repeat-masked Phrap with scaffolding), that explicitly identifies exact 20mer repeats from the shotgun data and removes them prior to the assembly. The established software is used to compute meaningful error probabilities for each base. Clone-end-pairing i...

  15. Simulace dynamiky vozidla využitím software V-REP

    OpenAIRE

    2016-01-01

    Tato práce se zabývá modelováním dynamiky a vizualizací experimentálního vozidla CAR4 v programu V-REP. V první části se práce zabývá představením a možnostmi programu V-REP. V další části je realizováno modelování vozidla CAR4 s následným řízením. K řízení je využit program V-REP a Matlab. V poslední fázi proběhlo testování modelu v simulaci. This theasis deals with modeling dynamics and visualization of experimental vehicle CAR4 in software V-REP. The first part shows introduction with V...

  16. Dictadura, democracia, república: Un análisis conceptual

    OpenAIRE

    Peña, Lorenzo

    2009-01-01

    Conferencia magistral sobre los conceptos de democracia, dictadura y república. "Memoria del Primer Encuentro Internacional sobre el poder en el pasado y el presente de América Latina" coord. por Francisco Lizcano y Guadalupe Zamudio Toluca: Universidad Autónoma del Estado de México, 2009 pp. 29-60. ISBN 978-607-422-069-8.

  17. Genetic Diversity and Evidence for Transmission of Streptococcus mutans by DiversiLab rep-PCR.

    Science.gov (United States)

    Momeni, Stephanie S; Whiddon, Jennifer; Cheon, Kyounga; Ghazal, Tariq; Moser, Stephen A; Childers, Noel K

    2016-09-01

    This two-part study investigated the genetic diversity and transmission of Streptococcus mutans using the DiversiLab repetitive extragenic palindromic PCR (rep-PCR) approach. For children with S. mutans and participating household members, analysis for evidence of unrelated child-to-child as well as intra-familial transmission was evaluated based on commonality of genotypes. A total of 169 index children and 425 household family members from Uniontown, Alabama were evaluated for genetic diversity using rep-PCR. Thirty-four unique rep-PCR genotypes were observed for 13,906 S. mutans isolates. For transmission, 117 child and household isolates were evaluated for shared genotype (by child and by genotype cases, multiple matches possible for each child). Overall, children had 1-9 genotypes and those with multiple genotypes were 2.3 times more likely to have caries experience (decayed, missing and filled teeth/surfaces>0). Only 28% of children shared all genotypes within the household, while 72% had at least 1 genotype not shared with anyone in the household. Children had genotype(s) not shared with any household members in 157 cases. In 158 cases children and household members shared a genotype in which 55% (87/158 cases) were shared with more than one family member. Children most frequently shared genotypes with their mothers (54%; 85/158), siblings (46%; 72/158) and cousins (23%; 37/158). A reference library for S. mutans for epidemiological surveillance using the DiversiLab rep-PCR approach is detailed. The genetic diversity of S. mutans in this population demonstrated frequent commonality of genotypes. Evidence for both child-to-child and intra-familial transmission of S. mutans was observed by rep-PCR.

  18. Virginia Tech's K-9 unit to receive Kevlar vest from alumni organization

    OpenAIRE

    Dickerson, Susan

    2004-01-01

    Hokie, the Virginia Tech Police Department's German shepherd, will be presented with a custom-fitted Virginia Tech Kevlar bulletproof vest to protect him from all the dangers he faces while performing his daily duties.

  19. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Science.gov (United States)

    2013-03-05

    ... Employment and Training Administration Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service..., 2012, applicable to workers of Verizon Business Networks Services, Inc., Order Management...

  20. Arquitectura low tech. Refugio de emergencia con palets

    OpenAIRE

    Borreguero Sánchez, Laura

    2015-01-01

    Este estudio busca profundizar en una alternativa a la arquitectura actual rescatando materiales y técnicas que han sido utilizadas a lo largo de la historia pero que debido a las nuevas tecnologías se han ido perdiendo. Esta “nueva” forma de construir se conoce como arquitectura Low Tech. Así, Low Tech hace referencia a una arquitectura que no precisa de una gran tecnología y que se sirve de materiales y técnicas propios de cada lugar haciendo de éste un sistema económico e...

  1. Displacement in new economy labor markets: Post-displacement wage loss in high tech versus low tech cities.

    Science.gov (United States)

    Davis, Daniel J; Rubin, Beth A

    2016-11-01

    While scholars and politicians tout education as the salve to employment disruptions, we argue that the geography of the new economy, and the social closure mechanisms that geography creates, may be just as important as individuals' characteristics for predicting post-displacement wage loss (or gain). We use data from the 2012 Displaced Workers ement of the Current Population Survey and from the 2010 United States Census to test hypotheses linking local labor markets in different industrial contexts to post-displacement wage loss. Our results point to age as a closure mechanism, and to the partially protective effect of education in high-tech versus low-tech economic sectors. This study is the first to use national level data to examine how employment in high-tech cities influences post-displacement wages. These findings are relevant both for theorizing about the new economy and for public policy. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid

    Science.gov (United States)

    Moreno-del Álamo, María; de la Espina, Susana Moreno-Díaz; Fernández-Tresguerres, M. Elena; Giraldo, Rafael

    2015-01-01

    Upon binding to short specific dsDNA sequences in vitro, the N-terminal WH1 domain of the plasmid DNA replication initiator RepA assembles as amyloid fibres. These are bundles of single or double twisted tubular filaments in which distorted RepA-WH1 monomers are the building blocks. When expressed in Escherichia coli, RepA-WH1 triggers the first synthetic amyloid proteinopathy in bacteria, recapitulating some of the features of mammalian prion diseases: it is vertically transmissible, albeit non-infectious, showing up in at least two phenotypically distinct and interconvertible strains. Here we report B3h7, a monoclonal antibody specific for oligomers of RepA-WH1, but which does not recognize the mature amyloid fibres. Unlike a control polyclonal antibody generated against the soluble protein, B3h7 interferes in vitro with DNA-promoted or amyloid-seeded assembly of RepA-WH1 fibres, thus the targeted oligomers are on-pathway amyloidogenic intermediates. Immuno-electron microscopy with B3h7 on thin sections of E. coli cells expressing RepA-WH1 consistently labels the bacterial nucleoid, but not the large cytoplasmic aggregates of the protein. This observation points to the nucleoid as the place where oligomeric amyloid precursors of RepA-WH1 are generated, and suggests that, once nucleated by DNA, further growth must continue in the cytoplasm due to entropic exclusion. PMID:26423724

  3. High-tech exports from developing countries: A symptom of technology spurts or statistical illusion?

    OpenAIRE

    Martin Srholec

    2005-01-01

    Specialization in high-tech products is frequently used to capture technology intensity of exports. The literature suggests that developing countries are increasingly becoming exporters of high-tech products, and some may even be among the most deeply specialized countries in the field of high-tech exports. The paper scrutinizes the relevance of the taxonomies that classify exports by technological intensity in this context. It is shown that specialization in high-tech exports typically does ...

  4. Standard Tools for Measuring Post Implementation TECH MOD (Technology Modernization) Cost Savings.

    Science.gov (United States)

    2014-09-26

    Another con- tractor developed a formula based on the Cost Performance Report ( CPR ) which provides unit cost savings. The final contractor measured...DEPARTMENT OF DEFENSE INITIATIVES ........... 2 C. TECH MOD HISTORY ............ ...... ......... 3 D. THE TECH MOD PROCESS ........... ............ 4...Guide 4 Oct 1984). C. TECH MOD HISTORY The first Tech Mod planning started in late 1970 with the F-16 program and the need to improve the government

  5. RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

    Directory of Open Access Journals (Sweden)

    Smith Deborah F

    2007-04-01

    Full Text Available Abstract Background Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective protozoan parasites (such as the Kinetoplastid and Plasmodium species, they are implicated in immune evasion and have been shown to influence virulence and pathogenicity. RepSeq http://repseq.gugbe.com is a new database of amino acid repeat-containing proteins found in lower eukaryotic pathogens. The RepSeq database is accessed via a web-based application which also provides links to related online tools and databases for further analyses. Results The RepSeq algorithm typically identifies more than 98% of repeat-containing proteins and is capable of identifying both perfect and mismatch repeats. The proportion of proteins that contain repeat elements varies greatly between different families and even species (3–35% of the total protein content. The most common motif type is the Sequence Repeat Region (SRR – a repeated motif containing multiple different amino acid types. Proteins containing Single Amino Acid Repeats (SAARs and Di-Peptide Repeats (DPRs typically account for 0.5–1.0% of the total protein number. Notable exceptions are P. falciparum and D. discoideum, in which 33.67% and 34.28% respectively of the predicted proteomes consist of repeat-containing proteins. These numbers are due to large insertions of low complexity single and multi-codon repeat regions. Conclusion The RepSeq database provides a repository for repeat-containing proteins found in parasitic protozoa. The database allows for both individual and cross-species proteome analyses and also allows users to upload sequences of interest for analysis by the RepSeq algorithm. Identification of repeat-containing proteins provides researchers with a defined subset of proteins which can be analysed by expression profiling and functional characterisation, thereby facilitating study of pathogenicity

  6. ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS

    Directory of Open Access Journals (Sweden)

    Alves-Ferreira Marcelo

    2008-09-01

    Full Text Available Abstract Background Genome survey sequences (GSS offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive regions of the genome. A more precise estimation of the nature, quantity and variability of repetitive sequences very early in a genome sequencing project is of considerable importance, as such data strongly influence the estimation of genome coverage, library quality and progress in scaffold construction. Also, the elimination of repetitive sequences from the initial assembly process is important to avoid errors and unnecessary complexity. Repetitive sequences are also of interest in a variety of other studies, for instance as molecular markers. Results We designed and implemented a straightforward pipeline called ReRep, which combines bioinformatics tools for identifying repetitive structures in a GSS dataset. In a case study, we first applied the pipeline to a set of 970 GSSs, sequenced in our laboratory from the human pathogen Leishmania braziliensis, the causative agent of leishmaniosis, an important public health problem in Brazil. We also verified the applicability of ReRep to new sequencing technologies using a set of 454-reads of an Escheria coli. The behaviour of several parameters in the algorithm is evaluated and suggestions are made for tuning of the analysis. Conclusion The ReRep approach for identification of repetitive elements in GSS datasets proved to be straightforward and efficient. Several potential repetitive sequences were found in a L. braziliensis GSS dataset generated in our laboratory, and further validated by the analysis of a more complete genomic dataset from the EMBL and Sanger Centre databases. ReRep also identified most of the E. coli K12 repeats prior to assembly in an example dataset obtained by automated sequencing using 454 technology. The parameters controlling the algorithm behaved consistently and may be tuned to the properties

  7. CareerTech VISION 2012--Transforming CTE Together

    Science.gov (United States)

    Bray, Janet B.

    2012-01-01

    As the leader in career and technical education (CTE), the Association for Career and Technical Education (ACTE) understands the ongoing challenges faced by the CTE community. That is why ACTE has created CareerTech VISION 2012, a bold and visionary event that addresses the evolving needs of the global society and meets all individual and…

  8. Educating Students to Boost Innovation and High-tech Entrepreneurship

    DEFF Research Database (Denmark)

    Berg, Rolf Henrik

    Promoting innovative thinking among students is crucial to educating the workforce necessary for innovation-led economies. And high-tech entrepreneurs are a crucial source of creating new jobs. Innovation is not an exact discipline or a system one can just implement. By contrast, it is very much...

  9. Job Future's Bright for the Chefs of Muskingum Tech.

    Science.gov (United States)

    Hoffman, Carl

    1993-01-01

    A two-year culinary arts program at Muskingum College (Zanesville, Ohio) prepares students for jobs in an emerging service-based economy. Students receive intensive classroom instruction and hands-on learning in a high-tech kitchen. Twenty-five full-time and 12 part-time students are completing their first year in the program. (LP)

  10. High Touch in a High-Tech World

    Science.gov (United States)

    Gibson, Cindy L.

    2009-01-01

    In a world of high tech and low touch, it is easy for public relations programs to stray from tried-and-true interpersonal strategies long associated with solid communication planning. New technologies allow communications professionals to quickly send e-mails and telephone calls to selected groups. Social media sites provide users immediate…

  11. Virginia Tech study reveals predation-evolution link

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The fossil record seems to indicate that the diversity of marine creatures increased and decreased over hundreds of millions of years in step with predator-prey encounters, Virginia Tech geoscientists report in the proceedings of the National Academy of Science online early edition the week of Sept. 10.

  12. NASA Consortium awards funding to Virginia Tech's geospatial program

    OpenAIRE

    Davis, Lynn

    2004-01-01

    NASA has selected a partnership between the Virginia Space Grant Consortium (VSGC) and Virginia Tech to receive a $100,000 grant for geospatial education and work force development. The grant, awarded through the NASA Space Grant College and Fellowship program, allows the partners to continue the already successful Virginia Geospatial Extension Program that was established in July 2003.

  13. Functional Dyes, and Some Hi-Tech Applications

    Directory of Open Access Journals (Sweden)

    Reda M. El-Shishtawy

    2009-01-01

    Full Text Available An overview of the recent developments in functional dyes, which are useful for hi-tech applications for those based on optoelectronics, such as dye sensitized solar cells, photochromic dyes and biomedical applications, such as photodynamic therapy for the treatment of cancer and fluorescent sensors is presented.

  14. Asia's New High-Tech Competitors: An SRS Special Report.

    Science.gov (United States)

    Rausch, Lawrence M.

    This report profiles nine economies linked by Asian identity, yet marked by great economic and technological disparity, in order to project which economies will be full-fledged participants and competitors in tomorrow's high-tech product markets. Based on the various indicators of technological activity and competitiveness presented in this…

  15. Ten Niche Strategies To Commercialize New High-Tech Products

    NARCIS (Netherlands)

    Ortt, J.R.; Langley, D.J.; Pals, N.

    2013-01-01

    There are serious gaps in the scientific literature relating to niche strategies as a means for commercializing new high-tech products. In particular, there is no clarity about what types of niche strategies can be distinguished, or how a niche strategy can be selected to suit a certain ituation. In

  16. Virginia Tech to host Biodiversity Conservation in Agriculture Symposium

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    Virginia Tech will host the Biodiversity Conservation in Agriculture Symposium at its Caribbean Center for Education and Research in Punta Cana, the Dominican Republic, May 31 - June 2. The symposium is designed to promote inclusion of biodiversity conservation objectives in agricultural development activities.

  17. Virginia Tech administrator receives award from Philippine government

    OpenAIRE

    2004-01-01

    Philippine President Gloria Macapagal Arroyo has honored S. K. De Datta of Blacksburg, associate provost for international affairs at Virginia Tech, with a Presidential Citation Award. The award recognizes De Datta's contributions towards eradicating hunger through improved agricultural productivity and food security, particularly for the production of rice.

  18. Virginia Tech to compete in 2009 Solar Decathlon

    OpenAIRE

    Chadwick, Heather Riley

    2008-01-01

    The U.S. Department of Energy has announced that Virginia Tech will be one of 20 university teams selected to compete in its fourth Solar Decathlon, which will be held on the National Mall in Washington, D.C., in the fall of 2009.

  19. Virginia Tech team places fourth at Solar Decathlon 2005

    OpenAIRE

    Chadwick, Heather Riley

    2005-01-01

    A house designed and built by a team of students from Virginia Tech's College of Architecture and Urban Studies and College of Engineering placed fourth overall on Friday, Oct. 14, at Solar Decathlon 2005, an international competition sponsored by the Department of Energy held on the Mall in Washington, D.C.

  20. Suzhou Institute of Nano-tech and Nano-bionics

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ The Suzhou Institute of Nano-tech and Nano-bionics is co-established by CAS, the provincial government of Jiangsu, and the municipal government of Suzhou, a time-honored urban center and picturesque tourist resort in the Yangtze delta.

  1. A new partnership: joint ventures and high-tech imaging.

    Science.gov (United States)

    Rutherford, R M

    1987-01-01

    Today joint ventures are a viable option for acquiring high-tech, high-priced imaging equipment. In this article based on his RSNA Associated Sciences presentation, Mr. Rutherford discusses a variety of issues concerning joint ventures: planning, tax considerations, structure and the ethics question.

  2. ASM International : Family tech enterprise grows up: Part A

    NARCIS (Netherlands)

    Lachotzki, F.W.I.; Schuit, S.R.; Olson, M.A.

    2012-01-01

    High-tech innovation is something not confined to the US, and indeed for decades the Dutch-based company ASMI has been a strong worldwide competitor in the market for the highly-complicated machines which manufacture the semi-conducter chips which are to be found in all modern-day electronic devices

  3. Employment and Earnings in High-Tech Ethnic Niches

    Science.gov (United States)

    Lee, Jennifer C.

    2013-01-01

    The increase in high-skilled immigrants to the United States coincided with the expansion of the high-technology sector, and now a large share of Asian immigrants concentrate in high-tech industries. Despite much research on the relationship between ethnic concentration and labor market outcomes, the association between ethnic niche employment and…

  4. Business, industry, government preview energy research at Virginia Tech Showcase

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    The Nov. 29-30 Energy Research Engagement Showcase offers business and community leaders the opportunity to learn about more than 300 energy-related activities at Virginia Tech, as well as energy efforts by faculty members at other public universities in Virginia.

  5. Examination of the New Tech Model as a Holistic Democracy

    Science.gov (United States)

    Bradley-Levine, Jill; Mosier, Gina

    2017-01-01

    Using the Degrees of Democracy Framework (Woods & Woods, 2012), we examined eight New Tech (NT) high schools to determine the extent to which they demonstrated characteristics of holistic democracy. We collected qualitative data, including observations and interviews during the fourth year of implementation. Findings indicated that the eight…

  6. CHARCOAL PACKED FURNACE FOR LOW-TECH CHARRING OF BONE

    DEFF Research Database (Denmark)

    Jacobsen, P.; Dahi, Elian

    1997-01-01

    A low-tech furnace for charring of raw bone using char coal is developed and tested. The furnace consists of a standard oil drum, fitted with simple materials as available in every market in small towns in developing counties. 80 kg of raw bone and 6 kg of charcoal are used for production of 50 k...

  7. Report on Virginia Tech Shootings Urges Clarification of Privacy Laws

    Science.gov (United States)

    Fischer, Karin

    2007-01-01

    Educators, mental-health officials, and law-enforcement officers often do not share information about troubled students because they are confused by what they can disclose under complex and overlapping privacy laws, according to a report on the Virginia Tech shootings. Attorney General Alberto R. Gonzales and two other Bush cabinet secretaries…

  8. Another Innovation from High Tech High--Embedded Teacher Training

    Science.gov (United States)

    Griswold, Janie; Riordan, Rob

    2016-01-01

    High Tech High School's teaching internship program blends on-the-job work with classroom theory. Interns spend two years working as full teachers as they take courses. The program serves three large purposes: Train new teachers and build capacity in the HTH organization; train teachers in and beyond HTH for success in a wide range of contexts;…

  9. TRAINING EMPLOYEES TO WORK WITH HI-TECH EQUIPMENT

    Directory of Open Access Journals (Sweden)

    M. A. Dremina

    2016-01-01

    Full Text Available The aim of the study is to describe a research relying on the capabilities of networking, which improves the quality of vocational training of skilled workers that are intended to work with new hi-tech equipment.Methods. Methods of system and comparative analysis, modeling, synthesis and generalization are used. Specification of the model of workers training offered by authors is carried out on the basis of deep interviews to experts – the representatives of the large enterprises who are carrying out training of the personnel.Results. Social and pedagogical contradictions are revealed, on the one hand, in the growing need for highly professional personnel for hi-tech productions, and, on the other hand, in insufficiently effective countermeasures of the system of vocational education and training on closing actual requirements of productions. The discrepancies reducing the quality of preparation of skilled workers are revealed by comparative analysis of competences based on an ideal competence model of the trainer and teacher of VET with the competences presented in educational both professional standards and the discussed projects. Characteristics of the existing pedagogical process in the hi-tech production environment are described. For the purpose of quality improvement of the pedagogical process, the network format of interactions of the enterprise, educational and the business organizations is offered.Scientific novelty. The concept «pedagogical process» for the purpose of making it more instrumental is specified; it joins a technological process and the design of its ideal model for the hi-tech production environment. The unique network project including design and development of innovative manuals and teaching materials for the welding equipment of Fronius International GmbH.Practical significance. The research results can be useful to the management of staff development and career advancement of hi-tech productions, and VET

  10. práctica del turismo rural en la República de Cuba

    Directory of Open Access Journals (Sweden)

    Isis Alejandra Camargo Toribio

    2005-01-01

    Full Text Available El presente trabajo incluye parte de los resultados que se obtuvieron en la tesis doctoral “Aportaciones metodológicas para la implementación del turismo rural en la República de Cuba. Estudio de caso: zona turística de Viñales” (Camargo, 2003. El objetivo principal de este artículo es conocer las preferencias de los clientes internacionales para la práctica del turismo rural, modalidad que no está establecida de forma consciente en la República de Cuba y que, de acuerdo con el potencial naturalcultural existente, tiene amplias posibilidades para su introducción. Con este fin se aplica una encuesta donde los viajeros evalúan, en una escala ascendente, la importancia que le conceden a un conjunto de elementos para la práctica de la modalidad rural

  11. [Stain hybridization method with pRepHind probe for the diagnosis of Plasmodium falciparum].

    Science.gov (United States)

    Moleón Borodowsky, I

    1992-01-01

    A study was conducted on the parasitemia detection level and the specificity of the pRepHind DNA probe for diagnosing Plasmodium falciparum by the stain hybridization method. The parasitemia detection level was studied by using dilutions of a P. falciparum in vitro culture, adjusted by direct microscopic examination to 1; 0.1; 0.01; 0.001; 0.0001 and 0.00001% of parasited red cells. Specificity was increased by using DNA extractions from P. Yoelii, P. berghei and human leucocytes. The results showed that the method was able to detect 0.0001% of parasitemia starting from DNA extractions of 100 L infected red cells. The pRepHind probe only detected specifically DNA from P. falciparum. It is concluded that the method is suitable for being used in the diagnosis of infection due to P. falciparum.

  12. A república e o sonho The republic and its dream

    Directory of Open Access Journals (Sweden)

    Maria Tereza Chaves de Mello

    2011-06-01

    Full Text Available O desencanto com a República brasileira tem sido tema de reflexões desde os seus momentos iniciais. Buscando os conteúdos concretos dos sonhos republicanos na década de 1880 e na Primeira República vamos achar uma importante defasagem entre eles não exatamente em função do marco cronológico, mas do grupo social que, respectivamente, os acalentou.The disillusion with the Brazilian Republic since its first days has been a topic of academician reflexions. Examinating the concrete contents of the 1880`s and the First Republic republican dreams we will find a substantive difference between them. To be exact, this difference must not be related to the chronological demarcation but to the social group that embraced each of them.

  13. Impact of gender and personality traits (BFI-10) on tech savviness

    DEFF Research Database (Denmark)

    Pavlicek, Antonin; Sudzina, Frantisek; Malinova, Ludmila

    2017-01-01

    Nowadays, it is necessary to use technology in various everyday activities. A certain level of what used to be called high-tech savviness is needed to access almost all modern services. The aim of this paper is to analyze if gender and personality traits (Big Five Inventory-10) influence self......-perceived tech savviness. A not so surprising finding is that gender influences self-perceived tech savviness, i.e. men consider themselves more tech savvy. Moreover, neuroticism has a negative and openness to experience has a positive impact on self-perceived tech savviness....

  14. Tratamiento tributario actual del comercio electrónico en la República Argentina

    OpenAIRE

    Martínez Giribone, María Silvana

    2010-01-01

    Tratamiento tributario actual del comercio electrónico en la República Argentina. PROBLEMA: ¿Constituye la legislación tributaria argentina aplicada a operaciones comerciales tradicionales un marco legal acorde para gravar operaciones de comercio electrónico? OBJETIVOS DE LA INVESTIGACION OBJETIVO GENERAL Analizar la aplicación de la legislación tributaria argentina para operaciones de comercio tradicionales en el comercio electrónico. OBJETIVOS ESPECIFICOS Ana...

  15. Vanguardismo y problemática del film alemán de la República de Weimar

    OpenAIRE

    Sánchez-Biosca, Vicente

    1985-01-01

    El presente artículo trata de examinar las aproximaciones historiográficas realizadas al cine producido en la República de Weimar, desde el llamado expresionismo hasta las corrientes realistas, pasando por el Kammerspielfilm.

  16. A Comparison of Molecular Typing Methods Applied to Enterobacter cloacae complex: hsp60 Sequencing, Rep-PCR, and MLST

    Directory of Open Access Journals (Sweden)

    Roberto Viau

    2017-02-01

    Full Text Available Molecular typing using repetitive sequenced-based PCR (rep-PCR and hsp60 sequencing were applied to a collection of diverse Enterobacter cloacae complex isolates. To determine the most practical method for reference laboratories, we analyzed 71 E. cloacae complex isolates from sporadic and outbreak occurrences originating from 4 geographic areas. While rep-PCR was more discriminating, hsp60 sequencing provided a broader and a more objective geographical tracking method similar to multilocus sequence typing (MLST. In addition, we suggest that MLST may have higher discriminative power compared to hsp60 sequencing, although rep-PCR remains the most discriminative method for local outbreak investigations. In addition, rep-PCR can be an effective and inexpensive method for local outbreak investigation.

  17. Reps võib kõrvale heita kümme miljonit maksnud õppekava / Dagne Hanschmidt

    Index Scriptorium Estoniae

    Hanschmidt, Dagne

    2005-01-01

    TÜ õppekavade arenduskeskus ja AS Bit koostavad mõlemad riikliku õppekava, lähtudes erinevatest põhimõttest. Haridus- ja teadusminister Mailis Reps ei ole avaldanud, kumba õppekava varianti ta eelistab

  18. RepPop: a database for repetitive elements in Populus trichocarpa

    Directory of Open Access Journals (Sweden)

    Xu Ying

    2009-01-01

    Full Text Available Abstract Background Populus trichocarpa is the first tree genome to be completed, and its whole genome is currently being assembled. No functional annotation about the repetitive elements in the Populus trichocarpa genome is currently available. Results We predicted 9,623 repetitive elements in the Populus trichocarpa genome, and assigned functions to 3,075 of them (31.95%. The 9,623 repetitive elements cover ~40% of the current (partially assembled genome. Among the 9,623 repetitive elements, 668 have copies only in the contigs that have not been assigned to one of the 19 chromosome while the rest all have copies in the partially assembled chromosomes. Conclusion All the predicted data are organized into an easy-to-use web-browsable database, RepPop. Various search capabilities are provided against the RepPop database. A Wiki system has been set up to facilitate functional annotation and curation of the repetitive elements by a community rather than just the database developer. The database RepPop will facilitate the assembling and functional characterization of the Populus trichocarpa genome.

  19. RepARK--de novo creation of repeat libraries from whole-genome NGS reads.

    Science.gov (United States)

    Koch, Philipp; Platzer, Matthias; Downie, Bryan R

    2014-05-01

    Generation of repeat libraries is a critical step for analysis of complex genomes. In the era of next-generation sequencing (NGS), such libraries are usually produced using a whole-genome shotgun (WGS) derived reference sequence whose completeness greatly influences the quality of derived repeat libraries. We describe here a de novo repeat assembly method--RepARK (Repetitive motif detection by Assembly of Repetitive K-mers)--which avoids potential biases by using abundant k-mers of NGS WGS reads without requiring a reference genome. For validation, repeat consensuses derived from simulated and real Drosophila melanogaster NGS WGS reads were compared to repeat libraries generated by four established methods. RepARK is orders of magnitude faster than the other methods and generates libraries that are: (i) composed almost entirely of repetitive motifs, (ii) more comprehensive and (iii) almost completely annotated by TEclass. Additionally, we show that the RepARK method is applicable to complex genomes like human and can even serve as a diagnostic tool to identify repetitive sequences contaminating NGS datasets.

  20. A method mediated AAVS1 recombination with Rep mRNA and homologous arms

    Institute of Scientific and Technical Information of China (English)

    Qiantong Xiang; Linian Huang; Sijia Guo; Fang Chen; Xiaojun Zha; Bing Chen; Liangdan Sun; Haisheng Zhou; Depei Liu

    2012-01-01

    The adeno-associated virus (AAV) genome can be stably integrated into the AAVS1 region of human chromosome 19 (19q13.4-qter) with the assistance of Rep68/78 protein.In the current models of AAV integration in a locusspecific manner,the foreign genes were randomly inserted into the AAVS1 region,which contains several functional genes.As random integration in this region may lead to insertion mutations and disrupt normal gene expression or critical signaling pathways of the host cells,it is necessary to find a precise insertion site in the AAVS1 region.Homologous recombination is the most accurate and versatile mechanism for such site-specific integration.To investigate site-specific integration in the AAVS1 region,a targeted vector containing two homologous arms derived from AAVS1 and a reporter gene was transfected into HeLa cells with or without Rep68/78 mRNA.The results indicated that transient expression of Rep68/78 in HeLa cells improved integration of the gene of interest at the AAVS1 locus in a site-specific manner.Compared with locus-specific integration reported in previous studies,sitespecific integration may minimize the risk associated with random DNA integration in the AAVS1 region,which might be helpful for gene therapy.

  1. Design and Implementation of Reconfigurable Embedded Processor (REP for AUV using FPGA

    Directory of Open Access Journals (Sweden)

    Mohd. Rizal Arshad

    2012-09-01

    Full Text Available The superscalar pipeline is something that the REP architecture resembles. The features that are similar in both architectures include rename, decode, fetch as well as in-order front-ends parts as substituted by dispatch units. The physical register file, execute unit, dynamic scheduler and task queue are contained by the out of-order execution core. The architecture also contains the REP that beholds an integrated system of shared-memory. A number of experiments with realistic benchmarks and an FPGA environment are used to synthesize design. The experiments conducted yielded in results that prove that the new architecture of the REP leads to higher performance of applications because of decreased processing time. And the core reason for the deduction of processing time is the simplified complexity of the frequency and area of the architecture. The results show that the least error tolerance is 1m by particle filter. Also, the optimum iteration level is 20 to get enhanceable navigation data for AUV.

  2. Realizace 3D tiskárny typu RepRap

    OpenAIRE

    Sochor, Marek

    2015-01-01

    Cílem bakalářské práce bude sestavení a ověření funkčnosti 3D tiskárny typu RepRap. Tiskárna bude sestavena z běžně dostupných dílů a pro zachování myšlenky RepRap také z dílů tisknutých. Po ověření funkčnosti 3D tiskárny bude vytisknuta identická součást na dvou typech tiskáren (3D tiskárna typu RepRap vs. profesionální tiskárna uPrint) za účelem zhodnocení a celkové analýzy, jak po stránce finanční, tak po stránce fyzické. Práce bude ukončena zhodnocením použitelnosti a konkurenceschopnosti...

  3. Modulation of pPS10 Host Range by Plasmid-Encoded RepA Initiator Protein

    Science.gov (United States)

    Maestro, Beatriz; Sanz, Jesús M.; Díaz-Orejas, Ramón; Fernández-Tresguerres, Elena

    2003-01-01

    We report here the isolation and analysis of novel repA host range mutants of pPS10, a plasmid originally found in Pseudomonas savastanoi. Upon hydroxylamine treatment, five plasmid mutants were selected for their establishment in Escherichia coli at 37°C, a temperature at which the wild-type form cannot be established. The mutations were located in different functional regions of the plasmid RepA initiation protein, and the mutants differ in their stable maintenance, copy number, and ability to interact with sequences of the basic replicon. Four of them have broadened their host range, and one of them, unable to replicate in Pseudomonas, has therefore changed its host range. Moreover, the mutants also have increased their replication efficiency in strains other than E. coli such as Pseudomonas putida and Alcaligenes faecalis. None of these mutations drastically changed the structure or thermal stability of the wild-type RepA protein, but in all cases an enhanced interaction with host-encoded DnaA protein was detected by gel filtration chromatography. The effects of the mutations on the functionality of RepA protein are discussed in the framework of a three-dimensional model of the protein. We propose possible explanations for the host range effect of the different repA mutants, including the enhancement of limiting interactions of RepA with specific host replication factors such as DnaA. PMID:12562807

  4. Translation initiation of the replication initiator repB gene of promiscuous plasmid pMV158 is led by an extended non-SD sequence.

    Science.gov (United States)

    López-Aguilar, Celeste; Ruiz-Masó, José A; Rubio-Lepe, Tania Samir; Sanz, Marta; del Solar, Gloria

    2013-07-01

    RepB is the pMV158-encoded protein that initiates rolling-circle replication of this promiscuous plasmid. Availability of RepB is rate-limiting for the plasmid replication process, and therefore the repB gene encoding the protein is subjected to strict control. Two trans-acting plasmid elements, CopG and the antisense RNAII, are involved in controlling the synthesis of the initiator at the transcriptional and translational level, respectively. In addition to this dual control of repB expression that senses and corrects fluctuations in plasmid copy number, proper availability of RepB also relies on the adequate functionality of the transcription and translation initiation regulatory signals. Translation of repB has been postulated to depend on an atypical ribosome binding site that precedes its start codon, although such a hypothesis has never been proved. To define sequences involved in translation of repB, several mutations in the translation initiation region of the repB mRNA have been characterized by using an Escherichia coli in vitro expression system wherein the synthesis of RepB was detected and quantified. We showed that translation of repB is not coupled to that of copG and depends only on its own initiation signals. The atypical ribosome binding site, as it was defined, is not involved in translation initiation. However, the sequence just upstream of the repB start codon, encompassing the proximal box of the atypical ribosome binding site and the four bases immediately downstream of it, is indeed important for efficient translation of repB. The high degree of conservation of this sequence among the rep genes of plasmids of the same pMV158 family supports its relevancy as a translation initiation signal in mRNAs without a recognizable Shine-Dalgarno sequence.

  5. Virginia Tech Wildlife Student Studies Cheetah Home Ranges

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The cheetah may be the world's fastest land animal, accelerating to high speeds in just a few steps, but within recent years the cheetahs of South Africa are battling the race for survival. To find remedies for this problem Peter Laver, a graduate student in fisheries and wildlife sciences in the College of Natural Resources at Virginia Tech, is expanding current research on home ranges of the cheetah population located in the Serengeti National Park in Tanzania, Africa.

  6. Information literacy training in AgroParisTech food studies

    OpenAIRE

    Agnès Grimal; Florence Dubois-Brissonnet; Elisabeth Dumoulin

    2015-01-01

    AgroParisTech professors and librarians in Food Science and Technology have developed information literacy instruction to help students find and use relevant information. The course trains students to develop information literacy competencies: to identify the information needed and define its nature and extent; to access the information with efficiency because they select and use methods, resources and retrieval systems most appropriate to the topic; to evaluate the used methods, information,...

  7. Life Sciences at the University of Yachay Tech in Ecuador

    OpenAIRE

    Graciela Salum; Si Amar Dahoumane; Agathos, Spiros N.

    2016-01-01

    Yachay Tech University, home for more than 900 students and growing, has entered a new era and made a step forward in its development and fulfillment of the hopes placed on it. Indeed, its Schools have launched their careers offering the students a wide range of choices among programs of high academic level. The School of Biological Sciences and Engineering has started its two careers. The first one, coined "Biology," is designed for students aiming to gain knowledge either in "Organism...

  8. Virginia Tech Wildlife Student Studies Cheetah Home Ranges

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The cheetah may be the world's fastest land animal, accelerating to high speeds in just a few steps, but within recent years the cheetahs of South Africa are battling the race for survival. To find remedies for this problem Peter Laver, a graduate student in fisheries and wildlife sciences in the College of Natural Resources at Virginia Tech, is expanding current research on home ranges of the cheetah population located in the Serengeti National Park in Tanzania, Africa.

  9. Orientace na konkurenci u hi-tech podniků

    Directory of Open Access Journals (Sweden)

    Lucie Kaňovská

    2013-10-01

    Full Text Available Purpose: The purpose of this paper is to examine the connection between market orientation and mainly competitor orientation and business performance at the hi-tech companies in the Czech Republic. Design/methodology/approach: The paper involves the New Method for measuring of market orientation. Data are collected through the survey and were used for the data analysis. Findings: The paper involves new aspects for perceiving competitor orientation, as a part of market orientation, and business performance. The result concurs with the results of researches of market orientation realized at this branch. Results show that competitor orientation has significant influence on business performance. Research limitations implications: The limitations are based on the methodology used for gaining data. However, the overall response rate is almost 20 %. The hi-tech industry is fast changing. From this reason, there can be many changes and it is impossible to repeat the research at the same companies. Practical implications: Our findings can help to understand market orientation and its relationship to competitors and business performance. Managers can use method for measuring of market orientation and can find out the level of market orientation at their companies. They can compare their results with the published average results of hi-tech companies. Originality/value: The originality of the paper comes from combining market orientation, the view of competition and business performance at hi-tech companies. The measurement of market orientation was made through the New Method. The model of the New method was constructed along after analysis of other 25 methods; we tried to eliminate the failings criticized in other methods.

  10. Virginia Tech to offer intensive English language refresher courses

    OpenAIRE

    2003-01-01

    Speaking and writing professionally with confidence are difficult for virtually everyone, but for those using a second language, these tasks pose a unique challenge. Virginia Tech's English Language Institute will address these needs by offering two intensive English language skills refresher classes during the semester break, from Jan. 5 to Jan. 16, 2004. Designed for graduate students, post-doctoral fellows, visiting scholars, and members of the international research community, this two-we...

  11. Entrepreneurship in high-tech and knowledge-intensive sectors

    DEFF Research Database (Denmark)

    Christensen, Patrizia V.; Madsen, Henning; Neergaard, Helle

    development of new enterprises in high-tech and knowledge-intensive sectors are analysed in relation to the educational and professional background of the entrepreneur/entrepreneurial team, as well as the personal and professional social networks of the entrepreneurs. The analysis is based on a theoretical...... framework combining theories of human and social capital. Secondary aspects addressed in the research project are questions of male vs. female entrepreneurship, internationalisation-globalisation, and business success/failure....

  12. Wearable high-tech gear for homeland security personnel

    Science.gov (United States)

    Venkateswarlu, Ronda; Hui Wei, Choo; Li Lian, Ngiam; Lim, E. T.; Zhu, Zijian; Yang, Mingjiang

    2006-05-01

    Recent homeland security problems in various countries indicate that fixed surveillance systems at important places are not adequate enough. As the security threats take new dimensions in future, mobile smart security personnel wearing high-tech gear will form the basic infrastructure. See first, listen first, detect first, track first, communicate first with peers, assess the threat and coordinate with security head-quarters are the functions of high-tech gear. This paper proposes a high-tech gear involving (i) hands-free and obtrusion-free textile-based wearable microphone array to capture users voice and interface with body-worn computer, (ii) microphone arrays embedded in textiles to listen and record others voices from a distance, (iii) miniature cameras embedded in the shirt to provide the user with omni vision (iv) wireless personal display as GUI hidden in textile or natural glasses, (v) GPS and body area network for positional awareness for information in the form of text or textile integrated, (vi) reconfigurable HW/SW for all the above functions configured in the form of a usual belt. The main focus of this paper is how to configure the high-tech gear with all these sophisticated functions to disappear into the natural wearables of the user giving him normal look in the public. This project is sponsored by Defence Science & Technology Agency, Ministry of Defence, Singapore. This paper covers multi-discipline technologies at system level, hence not possible to go into details of any subsystem. The main objective of this paper is to share our thoughts and get feedback. Progress and some critical design issues are discussed in this paper.

  13. Understanding Mexican High-tech Organizations: A Conceptualization Problem?

    OpenAIRE

    2001-01-01

    Working paper serie RMT (WPS 01-07), 23 p.; This study investigates the differences between intensive technology and low-tech firms located in Mexico, focusing on the Human Resources Management functions. 31 interviews and 50 answered questionnaires were used in this analysis. The results show that while Mexico is not yet a fully developed technological country. Indeed, technologically intensive firms are rare cases. Mexico is progressing rapidly towards a technologically developed country in...

  14. Information literacy training in AgroParisTech food studies

    Directory of Open Access Journals (Sweden)

    Agnès Grimal

    2015-10-01

    Full Text Available AgroParisTech professors and librarians in Food Science and Technology have developed information literacy instruction to help students find and use relevant information. The course trains students to develop information literacy competencies: to identify the information needed and define its nature and extent; to access the information with efficiency because they select and use methods, resources and retrieval systems most appropriate to the topic; to evaluate the used methods, information, and sources; to search, access and use information ethically and legally; to read, use and write bibliographic references.AgroParisTech trains two kinds of students. For Higher Education students (engineering students, the training takes place at their arrival in AgroParisTech, including courses and practical classes: role and management of information in organizations; information on plagiarism; resources in environment, food science and technology; use of relevant tools and methods for searching in databases; reference writing.For students attending a Master of Science, the training prepares them to produce a literature review. The curriculum includes: information about scientific integrity, plagiarism; information needed for a researcher; critical reading of a journal article; how to manage a literature review: resources used, information search with databases, full text access; reference writing.The students will use these information literacy skills along their studies as well as in their future jobs.

  15. Impact of capsid conformation and Rep-capsid interactions on adeno-associated virus type 2 genome packaging.

    Science.gov (United States)

    Bleker, Svenja; Pawlita, Michael; Kleinschmidt, Jürgen A

    2006-01-01

    Single-stranded genomes of adeno-associated virus (AAV) are packaged into preformed capsids. It has been proposed that packaging is initiated by interaction of genome-bound Rep proteins to the capsid, thereby targeting the genome to the portal of encapsidation. Here we describe a panel of mutants with amino acid exchanges in the pores at the fivefold axes of symmetry on AAV2 capsids with reduced packaging and reduced Rep-capsid interaction. Mutation of two threonines at the rim of the fivefold pore nearly completely abolished Rep-capsid interaction and packaging. This suggests a Rep-binding site at the highly conserved amino acids at or close to the pores formed by the capsid protein pentamers. A different mutant (P. Wu, W. Xiao, T. Conlon, J. Hughes, M. Agbandje-McKenna, T. Ferkol, T. Flotte, and N. Muzyczka, J. Virol. 74:8635-8647, 2000) with an amino acid exchange at the interface of capsid protein pentamers led to a complete block of DNA encapsidation. Analysis of the capsid conformation of this mutant revealed that the pores at the fivefold axes were occupied by VP1/VP2 N termini, thereby preventing DNA introduction into the capsid. Nevertheless, the corresponding capsids had more Rep proteins bound than wild-type AAV, showing that correct Rep interaction with the capsid depends on a defined capsid conformation. Both mutant types together support the conclusion that the pores at the fivefold symmetry axes are involved in genome packaging and that capsid conformation-dependent Rep-capsid interactions play an essential role in the packaging process.

  16. Transcriptomics of tomato plants infected with TYLCSV or expressing the central TYLCSV Rep protein domain uncover changes impacting pathogen response and senescence.

    Science.gov (United States)

    Lucioli, Alessandra; Perla, Carlo; Berardi, Alessandra; Gatti, Francesca; Spanò, Laura; Tavazza, Mario

    2016-06-01

    To establish a successful infection viruses need to overcome plant innate immune responses and redirect host gene expression for their multiplication and diffusion. Tomato yellow leaf curl Sardinia virus (TYLCSV) is a geminivirus, which causes significant economic losses in tomato. The multifunctional replication associated geminivirus protein (Rep) has an important role during viral infection. In particular, the Rep central domain spanning from aa 120 to 180 is known to interact with viral and host factors. In this study, we used long serial analysis of gene expression to analyse the transcriptional profiles of transgenic tomato plants expressing the first 210 amino acids of TYLCSV Rep (Rep210) and TYLCSV-infected wild-type tomato plants (Wt-Ty). Also, we compared these profiles with those of transgenic Rep130 tomatoes. Comparison of Wt-Ty and Rep210 libraries with the wild-type one identified 118 and 203 differentially expressed genes (DEGs), respectively. Importantly, 55% of Wt-Ty DEGs were in common with Rep210, and no ones showed opposite expression. Conversely, a negligible overlap was found between Rep130 DEGs and Wt-Ty and Rep210 ones. TYLCSV- and Rep210-repressed genes, but not induced ones, overlapped with the leaf senescence process. Interestingly, TYLCSV upregulates expression of genes involved in the negative regulation of programmed cell death (PCD), several of which were also regulated by the abscisic acid. Rep210 upregulated genes related to defence response, immune system processes and negative regulation of PCD. Collectively, our results support a model in which the Rep central domain has a pivotal role in redirecting host plant gene expression.

  17. Elecciones consulares en la República romana: control y manipulación

    OpenAIRE

    Muñiz Coello, Joaquín

    2013-01-01

    Tratamos en este artículo sobre la naturaleza de la autoridad del magistrado que preside los comicios electorales en la República romana, con relación a la liturgia de las diversas fases de los procesos y los actos previstos en los mismos. Consideramos relevante tratar de explicar las circuntancias de poder e influencia que caracterizaba al oficio, y la pugna que se desataba entre las factiones del senado, bien para colocar a sus candidatos, bien para influir en ...

  18. La teoría de la justicia en La República

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    1994-06-01

    Full Text Available En este artículo se presenta la teoría platónica de la justicia a nivel colectivoe individual en La República, siguiéndose los lineamientos del artículode G. Vlastos, "Justice and Happiness in theRepublic" (1971 . Pesea que se haya objetado a esta teoría de diversas maneras, ella aparece como habiendo iniciado la tradición utópica occidental de reflexión sobre elEstado justo.

  19. La democracia parlamentaria en la República de Weimar: entre el mito y la realidad

    OpenAIRE

    1998-01-01

    El artículo examina las principales teorías sobre el fracaso de la República de Weimar y el ascenso del nacional socialismo y llama la atención sobre la necesidad de estudiar en sí el período de Weimar para que, al margen de mitos de todo tipo, revele las deficiencias ideológicas y culturales de la primera experiencia democrática alemana. This article studies the main theories in relation to the failure of the Weimar Republic and the rise of the Nationalsocialist Dictatorship. Thus it call...

  20. Carreiras políticas e nepotismo na Terceira República francesa (1871-1940)

    OpenAIRE

    Niess,Alexandre

    2012-01-01

    Ainda que possa parecer improvável em um regime baseado no sufrágio universal masculino, as conexões familiares e o nepotismo cumpriram um papel extremamente importante na democracia representativa na Terceira República Francesa (1870-1940). Na verdade, essas práticas continuam importantes em algumas partes da esfera política até hoje. Este artigo examina detalhadamente as conexões e as práticas políticas no departamento de Marne, um espaço político onde vários tipos diferentes de conexões po...

  1. El separatismo en la República Popular China : El caso de los Uigures en Xinjiang

    OpenAIRE

    Sarli, Corina; Schiaffi, Belén

    2010-01-01

    Con la intención de profundizar el estudio de diferentes aspectos de las relaciones internacionales, se considera relevante analizar aquellos movimientos separatistas que trascienden los conflictos propios de un Estado. En este sentido, es nuestra intención centrarnos en uno de los conflictos internos mas importantes que esta atravesando el Estado que hoy es considerado la segunda economía mundial, la República Popular China (RPCh). Así, el objetivo de este trabajo es estudiar el conflicto...

  2. Design and Realization of Information System for Ningxia Sci-tech Special Commissioners

    Institute of Scientific and Technical Information of China (English)

    Changhong; WANG

    2013-01-01

    The information system for Ningxia sci-tech special commissioners is an application system for realizing information collection,management and sharing in the entrepreneurial process of sci-tech special commissioners. This paper introduces overall design ideas,system functions,key technologies and realization methods of the information system for Ningxia sci-tech special commissioners. Completion of construction and coming into operation of the information system bring new breakthrough for information management and data statistics of sci-tech special commissioners.

  3. Hi-Tech and Fong’s show up on the ITMA

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The once every four years ITMA exhibition was held recently in Barcelona, Spain.China Hi-Tech Group Corporation attaches great importance on the exhibition as it is a grand event of textile industry. The total exhibition area for Hi-Tech Group and its branch companies is 1100 square meters including 11 equipments of cotton spinning, dyeing and finishing, nonwoven, which represents part of the latest research results of Hi-Tech Group. Moreover other machinery products of Hi-Tech Group are demonstrated on the exhibition through video, pictures and brochure.

  4. Realidades de la independencia del Banco de la República Realities of the independence of the Banco de la República

    Directory of Open Access Journals (Sweden)

    Kalmanovitz Salomón

    1997-12-01

    Full Text Available La autonomía del banco central Colombiano es parte del proceso político que buscaba reducir el exagerado centralismo colombiano. Sin embargo el poder central no fue limitado en grado suficiente por la Constitución del 1991, como muestra el hecho de que el Ministro de Hacienda es el Presidente de la Junta Directiva del Banco de la República. Esto no sucede en ningun banco independiente del mundo por que los objetivos del gobierno son distintos a los del Banco Central y el Ministerio de Finanzas podría desviar al Banco de sus objetivos antiinflacionarios fundamentales. En Colombia, el gobierno no sólo participa en la Junta para acomodar sus múltiples objetivos sino también hace opocisión pública a la política monetaria y así la desacredita. El articulo plantea que el principio de no reelección hace que el horizonte de tiempo sea muy corto para que el gobierno coseche los frutos de una política de estabilización. El gobierno tiende a gastar en exceso para mejorar su imagen pública y el desajuste lo tiene que enfrentar el gobierno siguiente. De modo que la coordinación entre el Banco Central y el gobierno se torna muy conflictiva.The autonomy of the Central Bank of Colombia is part of a political process which seeks to reduce Colombia' s exaggerated centralismo However, central power was not limited to a sufficient degree by the Constitution of 1991, as demonstrated by the fact that the Minister of Finance is the President of the Board of Directors of the Banco de la República. This does not happen in any independent bank in the world, because the objectives of the government are different from those of the central bank, and the Minister of Finance could divert the Bank away from its fundamental anti-inflationary objectives. This article proposes that the principle of no reelection makes the time horizon very short for the government to reap the fruits of a stabilization policy. The government tends to spend in excess in order to

  5. Estado actual de la odontopediatría en la República Mexicana

    Directory of Open Access Journals (Sweden)

    Enrique E .-Huitzil-Muñóz

    2012-02-01

    Full Text Available La odontología pediátrica satisface un propósito muy especial con respecto de las especialidades odontológicas orientada a la prevención y curación de las enfermedades del sistema estomatognático durante la infancia y considerada como una especialidad muy completa y relativamente nueva se realiza una revisión acerca de la historia de la odontología pedíatrica en el mundo y en especial en México, recopilando información importante acerca de las instituciones universitarias que cuentan en su curricula con la especialidad, certificación y zonas de ubicación en la República Mexicana. Conclusiones: De acuerdo a las regiones de la República Mexicana en las que se encuentran ubicados los diversos posgrados, se concluye que de un total de 30 universidades que cuentan con la especialidad o maestría en odontopediatría, existen 7 en la denominada región centro y golfo y 6 en la región México D.F., estos datos concuerdan con el elevado número de habitantes que habitan esas regiones y que necesitan atención odontopediátrica cubriendo así la alta demanda del servicio por parte de los odontólogos posgraduados egresados.

  6. Averróis e a República de Platão

    Directory of Open Access Journals (Sweden)

    Pereira, Rosalie Helena de Souza

    2007-01-01

    Full Text Available Sobre República é o único comentário de uma obra de Platão deixado por Averróis, o comentador por antonomásia, diga-se de Aristóteles. Embora se tenha perdido o original árabe, a teles. Embora se tenha perdido o original árabe, a posteridade recebeu uma versão hebraíca e duas latinas. O comentário (ou paráfrase a República de Platão pode ser considerado uma obra original - divida em três livros - já que apenas um terço dela corresponde ao texto platônico. Além de apresentar conceitos aristotélicos retirados da Ética Nicomaquéia e de obras políticas de Al-Farabi, Averróis apresenta reflexões próprias e faz críticas à sociedade em que vive

  7. Four types of (super)conformal mechanics: D-module reps and invariant actions

    CERN Document Server

    Holanda, N L

    2014-01-01

    (Super)conformal mechanics in one dimension is induced by parabolic or hyperbolic/trigonometric transformations, either homogeneous (for a scaling dimension $\\lambda$) or inhomogeneous (at $\\lambda=0$, with $\\rho$ an inhomogeneity parameter). Four types of inequivalent (super)conformal actions are thus obtained. With the exclusion of the homogeneous parabolic case, dimensional constants are present. Both the inhomogeneity and the insertion of $\\lambda$ generalize the construction of Papadopoulos [CQG 30 (2013) 075018; arXiv:1210.1719]. Inhomogeneous $D$-module reps are presented for the $d=1$ superconformal algebras $osp(1|2)$, $sl(2|1)$, $B(1,1)$ and $A(1,1)$. For centerless superVirasoro algebras $D$-module reps are presented (in the homogeneous case for ${\\cal N}=1,2,3,4$; in the inhomogeneous case for ${\\cal N}=1,2,3$). The four types of $d=1$ superconformal actions are derived for ${\\cal N}=1,2,4$ systems. When ${\\cal N}=4$, the homogeneously-induced actions are $D(2,1;\\alpha)$-invariant ($\\alpha$ is cri...

  8. Four types of (super)conformal mechanics: D-module reps and invariant actions

    Energy Technology Data Exchange (ETDEWEB)

    Holanda, N.L.; Toppan, F., E-mail: linneu@cbpf.br, E-mail: toppan@cbpf.br

    2014-03-15

    (Super)conformal mechanics in one dimension is induced by parabolic or hyperbolic/trigonometric transformations, either homogeneous (for a scaling dimension λor inhomogeneous (at λ = 0, with ρ an inhomogeneity parameter). Four types of inequivalent (super)conformal actions are thus obtained. With the exclusion of the homogeneous parabolic case, dimensional constants are present. Both the inhomogeneity and the insertion of λ generalize the construction of Papadopoulos [CQG 30 (2013) 075018; arXiv:1210.1719]. Inhomogeneous D-module reps are presented for the d = 1 superconformal algebras osp(1∣2), sl(2∣1), B(1, 1) and A(1, 1). For centerless super Virasoro algebras D-module reps are presented (in the homogeneous case for N = 1; 2; 3; 4; in the inhomogeneous case for N = 1, 2, 3). The four types of d = 1 superconformal actions are derived for N = 1, 2, 4 systems. When N = 4, the homogeneously-induced actions are D(2, 1; α)-invariant (α is critically linked to λ); the inhomogeneously-induced actions are A(1, 1)-invariant. In d = 2, for a single bosonic field, the homogeneous transformations induce a conformally invariant power-law action, while the inhomogeneous transformations induce the conformally invariant Liouville action. (author)

  9. La segunda república: un discurso esquivo en la izquierda colombiana

    Directory of Open Access Journals (Sweden)

    Miguel Antonio Espinosa Rico

    2013-01-01

    Full Text Available El artículo trata sobre el estado actual de la realidad de la izquierda colombiana y su relación con la crisis del estado moderno colombiano. Se argumenta con FalsBorda (2001 y otros, que la globalización constituye un tema central para la consolidación del capitalismo colombiano, considerando con los autores revisados que el Estado Moderno representa la estructura sobre la cual se yergue el capitalismo en Occidente, pero que en Latinoamérica, y en especial, en la República Neogranadina, sienta las bases para la perpetuación del sistema. Analiza el sistema de división territorial colombiano para establecer premisas de dominio del régimen capitalista sobre el ciudadano común. Se concluye que el nuevo país solo es posible con sueño de la izquierda de la Segunda República, que reivindica las regiones como pilar fundamental para la dignidad del pueblo colombiano.

  10. Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola

    Science.gov (United States)

    Van Ham, Roeland C. H. J.; González-Candelas, Fernando; Silva, Francisco J.; Sabater, Beatriz; Moya, Andrés; Latorre, Amparo

    2000-01-01

    Buchnera aphidicola is an obligate, strictly vertically transmitted, bacterial symbiont of aphids. It supplies its host with essential amino acids, nutrients required by aphids but deficient in their diet of plant phloem sap. Several lineages of Buchnera show adaptation to their nutritional role in the form of plasmid-mediated amplification of key-genes involved in the biosynthesis of tryptophan (trpEG) and leucine (leuABCD). Phylogenetic analyses of these plasmid-encoded functions have thus far suggested the absence of horizontal plasmid exchange among lineages of Buchnera. Here, we describe three new Buchnera plasmids, obtained from species of the aphid host families Lachnidae and Pemphigidae. All three plasmids belong to the repA1 family of Buchnera plasmids, which is characterized by the presence of a repA1-replicon responsible for replication initiation. A comprehensive analysis of this family of plasmids unexpectedly revealed significantly incongruent phylogenies for different plasmid and chromosomally encoded loci. We infer from these incongruencies a case of horizontal plasmid transfer in Buchnera. This process may have been mediated by secondary endosymbionts, which occasionally undergo horizontal transmission in aphids. PMID:10984505

  11. RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis.

    Science.gov (United States)

    Glaab, Enrico; Schneider, Reinhard

    2015-07-01

    High-throughput omics datasets often contain technical replicates included to account for technical sources of noise in the measurement process. Although summarizing these replicate measurements by using robust averages may help to reduce the influence of noise on downstream data analysis, the information on the variance across the replicate measurements is lost in the averaging process and therefore typically disregarded in subsequent statistical analyses.We introduce RepExplore, a web-service dedicated to exploit the information captured in the technical replicate variance to provide more reliable and informative differential expression and abundance statistics for omics datasets. The software builds on previously published statistical methods, which have been applied successfully to biomedical omics data but are difficult to use without prior experience in programming or scripting. RepExplore facilitates the analysis by providing a fully automated data processing and interactive ranking tables, whisker plot, heat map and principal component analysis visualizations to interpret omics data and derived statistics. Freely available at http://www.repexplore.tk enrico.glaab@uni.lu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

  12. Generation of RGB-D data for SLAM using robotic framework V-REP

    Science.gov (United States)

    Gritsenko, Pavel S.; Gritsenko, Igor S.; Seidakhmet, Askar Zh.; Abduraimov, Azizbek E.

    2017-09-01

    In this article, we will present a methodology to debug RGB-D SLAM systems as well as to generate testing data. We have created a model of a laboratory with an area of 250 m2 (25 × 10) with set of objects of different type. V-REP Microsoft Kinect sensor simulation model was used as a basis for robot vision system. Motion path of the sensor model has multiple loops. We have written a program in V-Rep native language Lua to record data array from the Microsoft Kinect sensor model. The array includes both RGB and Depth streams with full resolution (640 × 480) for every 10 cm of the path. The simulated path has absolute accuracy, since it is a simulation, and is represented by an array of transformation matrices (4 × 4). The length of the data array is 1000 steps or 100 m. The path simulates frequently occurring cases in SLAM, including loops. It is worth noting that the path was modeled for a mobile robot and it is represented by a 2D path parallel to the floor at a height of 40 cm.

  13. La “República de Colombia” del Libertador Simón Bolívar

    Directory of Open Access Journals (Sweden)

    Carlos Uribe Celis

    2013-01-01

    Full Text Available Este ensayo traza el recorrido hist rico de la Rep blica de Colombia como la visualiz , la program y le dio vida el Libertador Sim n Bol var. La Rep blica de Colombia de Bol var era la uni n de lo que despu s constituyeron tres rep blicas distintas, hoy conocidas como Venezuela, Colombia y Ecuador. Bol var aprovecha parcialmente una idea original de Miranda (la Colombeia del sue o continental del ?recursor?, y este ensayo ilustra la con?guraci n del proyecto bolivariano, desde sus comienzos ajenos hasta la disoluci n del mismo, lo que pr cticamente coincide con la muerte del Libertador. La historia de Colombia se ubica aqu en el contexto de la lucha bolivariana por la Independencia del norte y centro de Suram rica.

  14. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and d-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    Lima A.S.G.

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  15. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and delta-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    A.S.G. Lima

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  16. Low Tech Hacking Street Smarts for Security Professionals

    CERN Document Server

    Wiles, Jack; Jabbusch, Jennifer; Rogers, Russ; Lowther, Sean

    2011-01-01

    Criminals using hacking techniques can cost corporations, governments, and individuals millions of dollars each year. While the media focuses on the grand-scale attacks that have been planned for months and executed by teams and countries, there are thousands more that aren't broadcast. Low Tech Hacking focuses on the everyday hacks that, while simple in nature, actually add up to the most significant losses. Attackers are using common techniques like social engineering, wireless hacking, and targeting and surveillance to gain access to valuable data. This book contains detailed descriptions

  17. Black Hole - Neutron Star Binary Simulations at Georgia Tech

    Science.gov (United States)

    Haas, Roland

    2009-05-01

    Mixed compact object binaries consisting of a black hole and a neutron star are expected to be not only one of the primary sources of gravitational radiation to be observed by interferometric detectors but also the central engine of short gamma-ray bursts. We report on the status of our effort at Georgia Tech to model these mixed binary systems using the moving puncture method. The results are obtained with an enhanced version our vacuum MayaKranc code coupled to the hydrodynamics Whisky code. We present preliminary results of gravitational waveforms and the disruption of the neutron star for simple polytropic equations of state.

  18. Come and see our new high-tech products!

    CERN Multimedia

    GS Department

    2010-01-01

    Since 1977, GMP has been active in the fields of laser, spectroscopy, electro-optics and micropositioning. Its mission is to link between suppliers of high tech products with the end users. On Wednesday 26 May between 10 and 12 a.m. - Room A, Main Building, (Bldg. 61/1-017) - you will be able to touch and try out our new laser products. Our specialized engineers will also be on hand to answer all your questions. A drink will be offered at the end of the presentation. There will also be the opportunity to plan meetings in the afternoon to further discuss and complicated questions.

  19. Development of a data capture tool for researching tech entrepreneurship

    DEFF Research Database (Denmark)

    Andersen, Jakob Axel Bejbro; Howard, Thomas J.; McAloone, Tim C.

    2014-01-01

    Startups play a crucial role in exploiting the commercial advantages created by new, advanced technologies. Surprisingly, the processes by which the entrepreneur commercialises these technologies are largely undescribed - partly due to the absence of appropriate process data capture tools....... This paper elucidates the requirements for such tools by drawing on knowledge of the entrepreneurial phenomenon and by building on the existing research tools used in design research. On this basis, the development of a capture method for tech startup processes is described and its potential discussed....

  20. Hi-Tech Skills Anticipation for Sustainable Development in Russia

    Directory of Open Access Journals (Sweden)

    Valery Gurtov

    2014-12-01

    Full Text Available It is evident that there is a heightened importance in Russia attributed to ensuring that students develop skills, which will enable them to be more productive and engaged citizens. This article deals with a skills anticipation methodology for seven hi-tech industries in Russia that resulted in the development of models for both soft and hard skills. There is a variety of widely applied methods – qualitative projection of labor market parameters, desk studies, documents analysis, foresight sessions, employers' and experts' surveys. As a result, new skills models are to help the specialists to effectively overcome the challenges, apply innovative decisions, and increase their technological knowledge.

  1. Pudong:Building a Hi-tech Platform

    Institute of Scientific and Technical Information of China (English)

    LiJialin; WuXinyi

    2003-01-01

    The approach of the knowledge economy means that Shanghai-China's most international city-is advancing towards world metropolis status.As the Chinese saying goes, “In the north is Zhongguancun,and in the south is Zhangjiangyuan.”In order to promote their respective economic growth,both Beijing and Shanghai focus on high technologies.Their importance,as represented by the Zhangjiang Hi-tech Park,is daily becoming more prominent in Pudong,and consequently,the whole of Shanghai.

  2. Prep/Tech: Volume 1, No. 1, Youth on homelessness

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    PREP/TECH is a skill development, academic enrichment program of U. of Toledo in Toledo OH and The Engineers Foundation of Ohio; it addresses the mathematics, science, language, and intellectual needs of about 100 African-American and Hispanic-American 7th, 8th, and 9th graders in Toledo. This summer, after 3 weeks of classes, the 80 students returned for a second 3 week session and were divided into two groups, one studying the growing problem of homelessness in America. This group researched and published a pamphlet on homelessness. This report is divided into: myths, causes, descriptions, and solutions. Finally, a brief account is given of the homelessness project.

  3. Desplazando al Rey en la escuela de la nueva nación mexicana: "el catecismo de República"

    Directory of Open Access Journals (Sweden)

    María Adelina ARREDONDO LÓPEZ

    2010-03-01

    Full Text Available RESUMEN: Este artículo estudia cómo un texto escolar, como el catecismo político de la nueva República de México, contribuye a desplazar de la escuela primaria la presencia colonial española, representada en el Rey, por nuevas imágenes de las instituciones de la naciente República de México. ABSTRACT: This paper studie how a textbook, the politic catechism of Mexican Republic, contribute to suplant the Spanish King instead the new images of the recent Mexican Republic during the emancipation process.

  4. Impact of Capsid Conformation and Rep-Capsid Interactions on Adeno-Associated Virus Type 2 Genome Packaging

    OpenAIRE

    Bleker, Svenja; Pawlita, Michael; Kleinschmidt, Jürgen A.

    2006-01-01

    Single-stranded genomes of adeno-associated virus (AAV) are packaged into preformed capsids. It has been proposed that packaging is initiated by interaction of genome-bound Rep proteins to the capsid, thereby targeting the genome to the portal of encapsidation. Here we describe a panel of mutants with amino acid exchanges in the pores at the fivefold axes of symmetry on AAV2 capsids with reduced packaging and reduced Rep-capsid interaction. Mutation of two threonines at the rim of the fivefol...

  5. Presencia y bioacumulación de productos de cuidado personal en corales marinos de República Dominicana

    OpenAIRE

    De León Peguero, Ana Esther

    2016-01-01

    El objetivo del proyecto a desarrollar es determinar la presencia de determinados aditivos orgánicos que se utilizan en productos de cuidado personal como champú, gel de baño, maquillaje, cremas solares, etc, en aguas y arrecifes de coral de la República Dominicana. Recientemente se ha documentado que la presencia de este tipo de contaminantes es responsable del blanqueamiento de los corales en zonas del Pacífico y dada la preocupación creciente en la República. Dominicana por el mal estado ...

  6. Em busca do despertar: o fortalecimento da sociedade civil angolana após a Segunda República

    Directory of Open Access Journals (Sweden)

    Rodrigo de Souza Pain

    2006-01-01

    passagem da Primeira República, caracterizada por um Estado de Partido Único, por uma economia planificada e inspirada nos ideais marxistas e leninistas; para a Segunda República, ou seja, para uma economia de mercado, multipartidária, explicitando as adversidades advindas das diversas realidades sociais, políticas e culturais do espaço territorial angolano resultante do processo de colonização, para a formação e consolidação da democracia e da sociedade civil em Angola.

  7. Iberia : capital federal de la IIª República Española (Un proyecto de Rubio i Tuduri

    Directory of Open Access Journals (Sweden)

    Carlos Sambricio

    1996-01-01

    Full Text Available A los pocos meses de proclamarse, en 1931, la II República Española, Nicolás Rubio i Tuduri presentaba —en el marco de la Exposición organizada por la Asociación de Arquitectos de Cataluña, celebrada en la barcelonesa Galería Maragall— una propuesta un tanto sorprendente: el proyecto de una nueva Capital Federal de la República Española que él denominaba Iberia.

  8. The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

    Directory of Open Access Journals (Sweden)

    Louise Madsen

    Full Text Available The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97 plays a central role in degradation of misfolded secretory proteins via the ER-associated degradation pathway. This functional diversity of p97 depends on its association with various cofactors, and to further our understanding of p97 function it is important that these cofactors are identified and analyzed. Here, we isolate and characterize the human protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8 is a transmembrane protein that localizes to the ER membrane with its UBX domain facing the cytoplasm. Knock-down of Rep8 expression in human cells leads to a decreased association of p97 with the ER membrane and concomitantly a retarded degradation of misfolded ER-derived proteasome substrates. Thus, Rep8 tethers p97 to the ER membrane for efficient ER-associated degradation.

  9. Expression of full-length and truncated Rep genes from Mungbean yellow mosaic virus-Vigna inhibits viral replication in transgenic tobacco.

    Science.gov (United States)

    Shivaprasad, Padubidri V; Thillaichidambaram, P; Balaji, Vasudevan; Veluthambi, Karuppannan

    2006-12-01

    Mungbean yellow mosaic virus-Vigna (MYMV-Vig) is a bipartite geminivirus that causes a severe yellow mosaic disease in blackgram. An assay was developed to study MYMV-Vig replication by agroinoculation of tobacco leaf discs with partial dimers of the virus. This assay, in a non-host model plant, was used to evaluate pathogen-derived resistance contributed by MYMV-Vig genes in transgenic plants. Viral DNA accumulation was optimum in tobacco leaf discs cultured for 10 days after infection with Agrobacterium tumefaciens strain Ach5 containing partial dimers of both DNA A and DNA B of MYMV-Vig. Transgenic tobacco plants with MYMV-Vig genes for coat protein (CP), replication-associated protein (Rep)-sense, Rep-antisense, truncated Rep (T-Rep), nuclear shuttle protein (NSP) and movement protein (MP) were generated. Leaf discs from transgenic tobacco plants, harbouring MYMV-Vig genes, were agroinoculated with partial dimers of MYMV-Vig and analyzed for viral DNA accumulation. The leaf discs from transgenic tobacco plants harbouring CP and MP genes supported the accumulation of higher levels of MYMV-Vig DNA. However, MYMV-Vig accumulation was inhibited in one transgenic plant harbouring the Rep-sense gene and in two plants harbouring the T-Rep gene. Northern analysis of these plants revealed a good correlation between expression of Rep or T-Rep genes and inhibition of MYMV-Vig accumulation.

  10. 78 FR 52535 - Withdrawal of Approval of New Animal Drug Applications; Quali-Tech Products, Inc.; Bambermycins...

    Science.gov (United States)

    2013-08-23

    ...; Quali- Tech Products, Inc.; Bambermycins; Pyrantel; Tylosin; Virginiamycin AGENCY: Food and Drug... feeds, are no longer manufactured or marketed: NADA 097-980 for Quali-Tech TYLAN-10 (tylosin...

  11. Construction of Innovative Rural Sci-tech Service System in China

    Institute of Scientific and Technical Information of China (English)

    Xinyue; LI; Qiwei; DAI

    2013-01-01

    At the background of structural regulation of agriculture and industrialized development of rural areas,systematic thought and constructive recommendations are put forward on building innovative rural sci-tech service system in China from following 5 aspects. (1) In organizational system,rural sci-tech service associations should become nonprofit organizations that have independent legal entities. (2) In service object,it should take farmers as subject,new rural economic organizations as carrier,agricultural leading enterprises as handle,little village officials as joint,sci-tech special commissioner as link,and agricultural brokers as medium. (3) In information resources,it should enhance practicality construction and sharing. (4) In service methods and reform measures,it should combine information technology,expert technical consulting service,and sci-tech model base. (5) In policy support and input mechanism,it should follow the principle of diversification,set up government special funds,and formulate preferential policies to attract sci-tech talents to join in rural sci-tech services,and protect legal rights and interests of sci-tech personnel in rural sci-tech services.

  12. Do gender and personality traits (BFI-10) influence self-perceived tech savviness?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek

    2015-01-01

    Nowadays, it is necessary to use technology in various everyday activities. A certain level of what used to be called high-tech savviness is needed to access certain services. The aim of this paper is to analyze if gender and personality traits (Big Five Inventory-10) influence self-perceived tech...

  13. A Decision Support System for Identification and Evaluation of High-tech Products

    Institute of Scientific and Technical Information of China (English)

    GAO Chang-yuan; LIANG Jing-guo; CAO Xiu-ying

    2002-01-01

    According to high-tech product features and decision support system theory, a decision support system (DSS) for identification and evaluation of high-tech products has been designed which consists of the user interface subsystem, the data management subsystem, the model management subsystem and the knowledge management subsystem. This paper describes the function and the framework of the system.

  14. State of FinTech in Europe: Mutation perspectives of the banking sector

    OpenAIRE

    Marasco, Marco

    2017-01-01

    This paper studies the relationship between FinTech start-ups and the banking sector. The aim is to assess the impact that the FinTech sector might have on the business model and profitability of banks. Master [120] en sciences de gestion (Mons), Université catholique de Louvain, 2017

  15. When High Tech ceases to be High Growth: The Loss of Dynamism of the Cambridgeshire Regio

    NARCIS (Netherlands)

    Stam, E.; Martin, R.

    2012-01-01

    This paper analyses mechanisms of decline and renewal in high-tech regions, illustrated with empirical evidence on the Cambridgeshire high-tech region in the UK. The paper contributes to ecological (‘carrying capacity’) and evolutionary (path dependence) theories of regional development. It provides

  16. GATE Center for Automotive Fuel Cell Systems at Virginia Tech

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Douglas [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2011-09-30

    The Virginia Tech GATE Center for Automotive Fuel Cell Systems (CAFCS) achieved the following objectives in support of the domestic automotive industry: Expanded and updated fuel cell and vehicle technologies education programs; Conducted industry directed research in three thrust areas development and characterization of materials for PEM fuel cells; performance and durability modeling for PEM fuel cells; and fuel cell systems design and optimization, including hybrid and plug-in hybrid fuel cell vehicles; Developed MS and Ph.D. engineers and scientists who are pursuing careers related to fuel cells and automotive applications; Published research results that provide industry with new knowledge which contributes to the advancement of fuel cell and vehicle systems commercialization. With support from the Dept. of Energy, the CAFCS upgraded existing graduate course offerings; introduced a hands-on laboratory component that make use of Virginia Tech's comprehensive laboratory facilities, funded 15 GATE Fellowships over a five year period; and expanded our program of industry interaction to improve student awareness of challenges and opportunities in the automotive industry. GATE Center graduate students have a state-of-the-art research experience preparing them for a career to contribute to the advancement fuel cell and vehicle technologies.

  17. Study on Management System for Agricultural Sci-tech Achievement Transformation Funding Project

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Hong; YU; Jun

    2013-01-01

    Relying on the management system for agricultural sci-tech achievement transformation funding project in Zhejiang Province, on the basis of current situations and demand of agricultural sci-tech achievement transformation funding project management system, we present a B/S-structured and J2EE platform-based system which adopts MVC mode and integrates mainstream open-source frame technologies such as Spring, Struts2, ExtJs, TopLink and FreeMarker, etc. Practice has shown that this system provides an original model for management of sci-tech project application, and various projects can be expanded on this model. With the aid of this system, sci-tech project management personnel can be relieved from trivial manual works, so as to increase working efficiency and improve management level of sci-tech project management.

  18. Competitive low-tech manufacturing and challenges for regional policy in the European context

    DEFF Research Database (Denmark)

    Hansen, Teis; Winther, Lars

    2014-01-01

    Today, low-tech firms in high-wage countries are focusing on increasing investments in highly skilled labour and advanced machinery, incremental innovation and high value-added niches. Danish policy, however, gives little attention to the new specificities of low-tech manufacturing, and the under....... Conversely, user–producer interactions and machinery investments, which are critical to low-tech competitiveness, are disregarded by policies.......Today, low-tech firms in high-wage countries are focusing on increasing investments in highly skilled labour and advanced machinery, incremental innovation and high value-added niches. Danish policy, however, gives little attention to the new specificities of low-tech manufacturing...

  19. 环境因素对大肠杆菌REP-PCR指纹图谱稳定性影响研究%Effect of environmental factors of REP-PCR fingerprinting patterns stability of Escherichia coil

    Institute of Scientific and Technical Information of China (English)

    韩彦垒; 梁斌; 李冬梅; 苏洁; 关道明; 王耀兵

    2011-01-01

    Escherichia coli is an important indicator in fecal pollution, The E. Coli DN A fingerprinting stability is to restrict one of identifying techniques development of the microbial polluted sources. In order to solve this problem, the E. Coli K12( K12CFP) , which the green fluorescent protein (CFP) plasmid was transformed, were chose to make a research. Its DNA fingerprinting stability was under different environmental factors (temperature,sunlight time and salinity). The results showed that the green fluorescent protein (CFP) did not affect the REP-PCR fingerprinting patterns of E. Coli K12 and the REP-PCR fingerprinting pattern is highly stable under the different environmental factors, temperature, sunlight time and salinity.%大肠杆菌作为粪便污染指示生物,其DNA指纹图谱稳定性是制约微生物污染源识别技术发展的瓶颈之一.本研究采用绿色荧光蛋白基因(GFP)标记后的Escherichia coli K12(K12GFP)为受试菌株,利用REP-PCR方法,对大肠杆菌在不同温度、光照、盐度条件下其DNA指纹图谱的稳定性进行了研究.结果表明,绿色荧光蛋白基因的标记不影响E.coli K12的REP-PCR指纹图谱;且大肠杆菌在不同温度、光照、盐度条件下REP-PCR指纹图谱具有高度的稳定性.

  20. Eficacia publicitaria: El caso de IKEA y 'La República Independiente de Tu Casa'

    OpenAIRE

    Núñez Ramírez, Marta

    2014-01-01

    L'estudi pretén aprofundir en l'àmbit de l'avaluació de l'eficàcia publicitària, a través de l'anàlisi d'un cas concret: l'anunci d'IKEA 'Benvingut a la República Independent de casa teva' de l'any 2006. Primerament, s'intenta explicar en què consisteix el concepte d'eficàcia, es reflexiona sobre la seva relació o no amb les vendes que aconsegueix generar una marca, i s'obren vies sobre criteris d'avaluació útils per a la investigació. S'arriba a una primera observació: la importància dels ob...

  1. Triatoma baccalaureatus: sobre a crise do bacharelismo na Primeira República

    Directory of Open Access Journals (Sweden)

    Ricardo Sontag

    2010-07-01

    Full Text Available Este trabalho pretende abordar a crise do bacharelismo (hegemônico durante o Império nas primeiras décadas do século XX, principalmente por meio da literatura, relacionando-a com as transformações que estavam ocorrendo no ensino e no saber jurídico. Ao longo da Primeira República, à medida que outras figuras passam a ganhar espaço no cenário público (engenheiros, sanitaristas, etc., o bacharelismo passa a ser duramente questionado, aprofundando as críticas que já vinham sendo levadas a cabo no final do século XIX pelo positivismo cientificista; a partir disso, começa a se formar a cultura do tecnicismo jurídico. Palavras-chave: História do Direito. Bacharelismo. Positivismo cientificista. Tecnicismo.

  2. Agripino Nazareth e o movimento operário da Primeira República

    Directory of Open Access Journals (Sweden)

    Aldrin Armstrong Silva Castellucci

    2012-12-01

    Full Text Available Agripino Nazareth (1886-1961 se destacou como liderança socialista do movimento operário brasileiro ao longo da Primeira República. Depois de 1930, passou a integrar os quadros do Ministério do Trabalho e da Justiça do Trabalho, aposentando-se como Procurador do Trabalho no início de 1960 e falecendo no dia 1º de agosto de 1961. Neste artigo, analisaremos o primeiro momento de sua trajetória, quando se associou a outros militantes das mais variadas correntes político-ideológicas, envolvendo-se em movimentos de diversos matizes e assumindo diferentes compromissos.

  3. Site-specific integration by the adeno-associated virus rep protein.

    Science.gov (United States)

    Recchia, Alessandra; Mavilio, Fulvio

    2011-10-01

    Inserting genetic information at precise locations into the human genome has been the goal of gene transfer technology for almost two decades. The spectacular progress of mammalian genetics has led to the development of technology for genome editing and homologous recombination in human somatic cells that is finally approaching efficiency compatible with clinical application. Site-specific integration, or the insertion of genes at known locations by enzymes with target recognition capacity, has progressed slowly but steadily in recent years, and could very well be the basis of the next generation of gene transfer technology. This review focuses on the use of Rep, the replicase/integrase of the adeno-associated virus (AAV), to insert genes at the natural AAV integration site on human chromosome 19. This region (AAVS1) has characteristics that make it an ideal target for somatic transgenesis.

  4. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    Directory of Open Access Journals (Sweden)

    José Nelson Bessa Maia

    2012-01-01

    Full Text Available Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930 no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização histórica pertinente dão sustentação à caracterização do período como uma fase de paradiplomacia financeira precoce.

  5. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    OpenAIRE

    José Nelson Bessa Maia; José Flávio Sombra Saraiva

    2012-01-01

    Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930) no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização históri...

  6. a Study on the Document Information Service of the National Agricultural Library for Agricultural Sci-Tech Innovation in China

    Science.gov (United States)

    Xu, Qian; Meng, Xianxue

    This paper presents the significant function of the Chinese National Agricultural Library (CNAL) in the agricultural sci-tech innovation system in China, analyses the development of collection and service in the CNAL, explores the challenge towards sustain and develop information services for the agricultural sci-tech research and innovation, at last proposes the strategy for sci-tech document information service development.

  7. 75 FR 21663 - Maysteel, LLC Including On-Site Leased Workers From Staff One, Badger Tech, Boyd Hunter, Seek...

    Science.gov (United States)

    2010-04-26

    ... Tech, Boyd Hunter, Seek, QPS, and Service First, Menomonee Falls, WI; Amended Certification Regarding..., including on-site leased workers from Staff One, Badger Tech, Boyd Hunter, Seek, and QPS, Menomonee Falls... Maysteel, LLC, including on-site leased workers from Staff One, Badger Tech, Boyd Hunter, Seek, QPS,...

  8. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal

    NARCIS (Netherlands)

    Peters, A.K.; Leonards, P.E.G.; Zhao, B.; Bergman, A.; Denison, M.S.; Berg, van den M.

    2006-01-01

    The TEF system for dioxin-like compounds has included assignment of TEF values for mono-ortho polychlorinated biphenyls (MO-PCBs). Small traces of aryl hydrocarbon receptor (AhR)-active impurities could result in artifactually higher relative potency (REP) values. MO-PCBs -105, -118, -156, and -167

  9. 78 FR 53774 - Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10...

    Science.gov (United States)

    2013-08-30

    ... not available when FEMA REP-10 was first developed, such as smartphones and social media. Removes... Design Report) and planning aspects (ANS/Communication Plans) demonstrating the achievement of minimally... proposed policy does not have the force or effect of law. FEMA seeks comment on the proposed policy,...

  10. The OSIRIS Weight of Evidence approach: ITS for the endpoints repeated-dose toxicity (RepDose ITS)

    NARCIS (Netherlands)

    Tluczkiewicz, I.; Batke, M.; Kroese, D.; Buist, H.; Aldenberg, T.; Pauné, E.; Grimm, H.; Kühne, R.; Schüürmann, G.; Mangelsdorf, I.; Escher, S.E.

    2013-01-01

    In the FP6 European project OSIRIS, Integrated Testing Strategies (ITSs) for relevant toxicological endpoints were developed to avoid new animal testing and thus to reduce time and costs. The present paper describes the development of an ITS for repeated-dose toxicity called RepDose ITS which evalua

  11. Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics.

    Science.gov (United States)

    Pearce, J M; Anzalone, N C; Heldt, C L

    2016-08-01

    The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs. © 2016 Society for Laboratory Automation and Screening.

  12. La lucha contra la discriminación y la apatridia en la República Dominicana

    OpenAIRE

    Bridget WOODING

    2009-01-01

    Tras muchas décadas de migración irregular de haitianos que llegan a la República Dominicana para asentarse y trabajar, existe una población numerosa en situación incierta expuesta a frecuentes discriminaciones y abusos de los derechos humanos.

  13. Mida on vaja teha õpilaskodude arendamiseks? / Ale Sprenk, Karin Saare, Merike Mändla, Mailis Reps...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad Krabi põhikooli direktor, õpilaskodu mõtte algataja Ale Sprenk, Kasari põhikooli direktor Karin Saare, haridus- ja teadusministeeriumi üldharidusosakonna peaekspert Merike Mändla, riigikogu liige, endine haridusminister Mailis Reps ja Otepää gümnaasiumi direktor Aivo Meema

  14. Feature selection and data sampling methods for learning reputation dimensions: The University of Amsterdam at RepLab 2014

    NARCIS (Netherlands)

    Gârbacea, C.; Tsagkias, M.; de Rijke, M.

    2014-01-01

    We report on our participation in the reputation dimension task of the CLEF RepLab 2014 evaluation initiative, i.e., to classify social media updates into eight predefined categories. We address the task by using corpus-based methods to extract textual features from the labeled training data to

  15. Naturaleza jurídica de la Contraloría General de la República

    OpenAIRE

    Murillo, Mauro

    2014-01-01

    Todavía reina una confusión acerca de la naturaleza jurídica de la ContraloríaGeneral  de la República, pese a los 15 años de vigencia del texto constitucional, cuya insuficiente redacción es obviamente la causante del problema.

  16. Molecular characterization of Pasteurella multocida isolates obtained from poultry, ruminant, cats and dogs using RAPD and REP-PCR analysis

    Directory of Open Access Journals (Sweden)

    Hesamaddin Shirzad-Aski

    2016-09-01

    Full Text Available In the present study, Randomly Amplified Polymorphic DNA‌ (RAPD and Repetitive Extragenic Palindromic sequence-based Polymerase Chain Reaction (REP-PCR were used to characterize 131 isolates of Pasteurella multocida, originating from different healthy and diseased animal species obtained from several geographical regions of Iran. The RAPD and REP-PCR generated amplified products in the range of 300 to 3400 bp and 200 to 2850 bp, respectively. Among all of the P. multocida isolates, cluster analysis revealed that 63 clusters and nine untypable isolates and 81 clusters and six untypable isolates were produced with RAPD and REP-PCR methods, respectively. The results indicated that the REP-PCR method showed a slightly higher level of discrimination power in differentiating of P. multocida isolates as compared with RAPD. The results showed that a considerable level of genetic diversity exists among P. multocida isolates even in the isolates with the same animal or geographical origins. There was no host- and region-specific pattern. In addition, the isolates obtained from the healthy and diseased animal did not reveal any correlation genotypic profiles, which could be supported by the hypothesis that P. multocida is a strictly opportunistic pathogen. In conclusion, because of a large amount of genetic heterogeneityin the P. multocida isolates, Pasteurellosis may be caused by different clones in the same herd or animal.

  17. High-Tech Means High-Efficiency: The Business Case for EnergyManagement in High-Tech Industries

    Energy Technology Data Exchange (ETDEWEB)

    Shanshoian, Gary; Blazek, Michele; Naughton, Phil; Seese, RobertS.; Mills, Evan; Tschudi, William

    2005-11-15

    In the race to apply new technologies in ''high-tech'' facilities such as data centers, laboratories, and clean rooms, much emphasis has been placed on improving service, building capacity, and increasing speed. These facilities are socially and economically important, as part of the critical infrastructure for pharmaceuticals,electronics, communications, and many other sectors. With a singular focus on throughput, some important design issues can be overlooked, such as the energy efficiency of individual equipment (e.g., lasers, routers and switches) as well as the integration of high-tech equipment into the power distribution system and the building envelope. Among technology-based businesses, improving energy efficiency presents an often untapped opportunity to increase profits, enhance process control,maximize asset value, improve the work place environment, and manage a variety of business risks. Oddly enough, the adoption of energy efficiency improvements in this sector lags behind many others. As a result, millions of dollars are left on the table with each year ofoperation.

  18. DEMO_REP: A LABS TOOL FOR TEACHING DATA REPLICATION / DEMO_REP: HERRAMIENTA PARA LABORATORIOS EN LA ENSEÑANZA DE RÉPLICA DE DATOS

    Directory of Open Access Journals (Sweden)

    Ileane Martí Pérez

    2013-02-01

    Full Text Available The process of training professionals in information technologies is a key aspect in the development of the country. University Informatics Science is one of the main centers dedicated to this process, also has postgraduate training programs to further advanced topics not mentioned in the pregraduate. One such program is the "DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL," which has a number of courses to obtain expertise in the subject of databases in PostgreSQL Manager. In this paper show how affects in the understanding of the process of data replication, the use of the software tool "Demo_rep" for laboratory exercises replication. It also describes the main features of software tool.RESUMENEl proceso de formación de los profesionales en tecnologías de la informática es un aspecto clave en el desarrollo del país. La Universidad de las Ciencias Informáticas es uno de los principales centros que se dedica a este proceso, la misma consta de programas de formación postgraduada para profundizar en temas que no aparecen incluidos en los programas analíticos de las asignaturas de pregrado. Uno de estos programas es el “DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL”, el cual cuenta con una serie de cursos para lograr experticia en la temática de las bases de datos en el gestor PostgreSQL. En el presente trabajo se muestra cómo incide en la comprensión del proceso de la replicación de datos, la utilización de una herramienta informática “Demo_rep” para realizar los ejercicios de laboratorio de réplica. Se describe además las principales funcionalidades de la misma.

  19. Phylogenetic relationships, virulence factors and Rep-PCR epidemiological analysis of E. coli from human sources

    Directory of Open Access Journals (Sweden)

    Simona Caroppo

    2010-06-01

    Full Text Available The potential of Escherichia coli to cause of extra-intestinal infections was studied on a group of 94 clinical isolates. In this work, 32 E. coli isolates from urinary tract infections, 25 from bacteraemia, 12 from low respiratory tract infections, and 25 from the normal commensal flora were characterized for the phylogenetic type, the virulence factors (VFs carriage and the Rep-PCR clonal composition.The B2 phylogenetic type was predominant among the urinary isolates (59%, the B2 and D strains among the haematic isolates (32% and 32%.The A phylogenetic type was predominant among the commensal and the respiratory isolates (52% and 58% respectively.The distribution of the B2 type strains among the urinary isolates and of the D type strains among the faecal isolates was suggesting a urinary-origin for the B2 phylogenetic type isolates found in the blood and a direct faecal derivation for the haematic isolates with D phylogenetic type.Twenty-nine VFs were analyzed.The B2 and D type strains carried a higher burden of VFs than the A and B1 phylogenetic type strains (average of VFs/strain = 8 vs 3. Some of the VFs were homogeneously distributed among the phylogenetic types (fimH, iutA, fyuA, traT. The PAI, papGII, ibeA, KpsMTIII were exclusive of B2 and D phylogenetic type strains, while sfa/foc, focG, cnf1, hlyA and rfc were exclusively observed among the B2 type strains.The clustering analysis by Rep-PCR distinguished two groups of strains, the first including 96.77% of B2 and D type strains, while the second encompassing 91,5% of A and B1 type strains.

  20. Los médicos del exilio repúblicano en Venezuela

    Directory of Open Access Journals (Sweden)

    José Francisco Tinao Martín-Peña

    2009-11-01

    Full Text Available La guerra civil española provocó el exilio de un importante número de científicos e intelectuales. Dentro de ellos numerosos médicos saldrían de España obligados por su defensa de la República o su ideología democrática. Una gran mayoría se establecieron en América Latina. Venezuela es el segundo país donde más facultativos acoge, tras México. En el presente trabajo se analiza cuales fueron las circunstancias históricas que permitieron esta acogida, y se hace referencia a alguna de las personalidades y sus campos de trabajo en su nuevo país de acogida. Dentro de la historia social de la medicina española existe un espacio vacío sobre el exilio médico y sobre la represión interior ejercida físicamente o simplemente como depurados de numerosos médicos que se vincularon de distinto modo con los ideales de modernidad de la República Española.______________ABSTRACT:The Spanish Civil War led to the exile of a large number of scientists and intellectuals. Among them, many doctors escaped from Spain because of their defense of the Republic or their democratic ideology. A large majority were established in Latin America. Venezuela is the second country of welcome, after Mexico. In this paper we analyze what were the historical circumstances that allowed this host, and it is made reference to some personalities and their fields of work in their new host country. Within the social history of Spanish medicine, there is an empty space on the exile of this category and their internal repression or the purged of many doctors linked to the ideals of modernity of the Spanish Republic.

  1. Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI+

    Directory of Open Access Journals (Sweden)

    Fátima eGasset-Rosa

    2015-04-01

    Full Text Available The yeast translation termination factor Sup35p, by aggregating as the [PSI+] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native protein molecules, then assembling as large aggregates and fibers. Prions propagate epigenetically from mother to daughter cells by fragmentation of such assemblies. In the N-terminal prion-forming domain, Sup35p has glutamine/asparagine-rich oligopeptide repeats (OPRs, which enable propagation through chaperone-elicited shearing. We have engineered chimeras by replacing the polar OPRs in Sup35p by up to five repeats of a hydrophobic amyloidogenic sequence from the synthetic bacterial prionoid RepA-WH1. The resulting hybrid, [REP-PSI+], i was functional in a stop codon read-through assay in S. cerevisiae; ii generates weak phenotypic variants upon both its expression or transformation into [psi-] cells; iii these variants correlated with high molecular weight aggregates resistant to SDS during electrophoresis; and iv according to fluorescence microscopy, the fusion of the prion domains from the engineered chimeras to the reporter protein mCherry generated perivacuolar aggregate foci in yeast cells. All these are signatures of bona fide yeast prions. As assessed through biophysical approaches, the chimeras assembled as oligomers rather than as the fibers characteristic of [PSI+]. These results suggest that it is the balance between polar and hydrophobic residues in OPRs what determines prion conformational dynamics. In addition, our findings illustrate the feasibility of enabling new propagation traits in yeast prions by engineering OPRs with heterologous amyloidogenic sequence repeats.

  2. A Primeira República Portuguesa (1910-1926: partidos e sistema político

    Directory of Open Access Journals (Sweden)

    Baiôa, Manuel

    2014-04-01

    Full Text Available For historical, organisational, clientelist, violent and constitutional reasons the Portuguese Republican Party became the dominant party in the political system of the Portuguese First Republic (1910-1926. The opposition felt alternation via elections would be difficult to achieve so resorted to violent and unconstitutional practices to reach government. The Portuguese political parties modernised themselves in this period, but failed to turn into mass parties. In major cities they acted as a cadre party and in the rural area as a party of notables. The First Republic failed to take solid steps to democratise the political system were And Portugal remained tied to the liberal and elitist tradition of the nineteenth century, although in a republican version.El Partido Republicano Portugués se convirtió en el partido dominante del sistema político de la Primera República Portuguesa (1910-1926 debido a causas históricas, organizacionales, clientelistas, violentas y constitucionales. La oposición sentía que difícilmente conseguiría la alternancia política a través de elecciones, y por lo tanto, recurre a prácticas violentas e inconstitucionales para llegar al gobierno. Los partidos políticos portugueses se modernizaron en este período, pero no se convirtieron en partidos de masas. En las principales ciudades actuaban como partidos de cuadros y en las zonas rurales como partidos de notables. Durante la Primera República no se dieron pasos consistentes para democratizar el sistema político. Portugal se mantuvo ancorado a la tradición liberal y elitista del siglo XIX, aunque en una versión republicana.

  3. Petascale Simulation Initiative Tech Base: FY2007 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    May, J; Chen, R; Jefferson, D; Leek, J; Kaplan, I; Tannahill, J

    2007-10-26

    The Petascale Simulation Initiative began as an LDRD project in the middle of Fiscal Year 2004. The goal of the project was to develop techniques to allow large-scale scientific simulation applications to better exploit the massive parallelism that will come with computers running at petaflops per second. One of the major products of this work was the design and prototype implementation of a programming model and a runtime system that lets applications extend data-parallel applications to use task parallelism. By adopting task parallelism, applications can use processing resources more flexibly, exploit multiple forms of parallelism, and support more sophisticated multiscale and multiphysics models. Our programming model was originally called the Symponents Architecture but is now known as Cooperative Parallelism, and the runtime software that supports it is called Coop. (However, we sometimes refer to the programming model as Coop for brevity.) We have documented the programming model and runtime system in a submitted conference paper [1]. This report focuses on the specific accomplishments of the Cooperative Parallelism project (as we now call it) under Tech Base funding in FY2007. Development and implementation of the model under LDRD funding alone proceeded to the point of demonstrating a large-scale materials modeling application using Coop on more than 1300 processors by the end of FY2006. Beginning in FY2007, the project received funding from both LDRD and the Computation Directorate Tech Base program. Later in the year, after the three-year term of the LDRD funding ended, the ASC program supported the project with additional funds. The goal of the Tech Base effort was to bring Coop from a prototype to a production-ready system that a variety of LLNL users could work with. Specifically, the major tasks that we planned for the project were: (1) Port SARS [former name of the Coop runtime system] to another LLNL platform, probably Thunder or Peloton (depending

  4. Advanced Polymeric Materials for High-tech Innovations

    Institute of Scientific and Technical Information of China (English)

    TANG; BenZhong

    2001-01-01

    High technology is advancing our society and modernizing our life and advanced materials play an important role in the technological innovations. My research group has been working on the development of advanced polymeric materials and in this talk I will report our recent work on the creation of new conjugated polymers with novel molecular structures and unique materials properties.1-18 Our work include the design of molecular structures of monomeric building blocks, development of stable, effective and environmentally benign "green” polymerization catalysts, discovery of new polymerization reactions, synthesis of functional macromolecules, fabrication of nanodimensional composites, assembly and control of hierarchical structures, and construction of electrooptical devices. We have revealed the liquid crystallinity, light emission, photoconductivity, optical limiting, nano-hybridization, solvatochromism, optical activity, self-organization, and biological activity of the linear polyacetylenes and hyperbranched polyarylenes. The utilization of the advanced polymers and their interesting materials properties for high-tech innovations will be discussed.  ……

  5. PREFACE: Modern Technologies in Industrial Engineering (ModTech2015)

    Science.gov (United States)

    Oanta, E.; Comaneci, R.; Carausu, C.; Placzek, M.; Cohal, V.; Topala, P.; Nedelcu, D.

    2015-11-01

    The dominant feature of the current stage of society development is the update, refinement and innovation of the technological processes and products whose ultimate goal is to satisfy the market requirements. New and modern technologies should be considered in terms of their applicability in industry while the materials can lead to an increase in the quality of the end products. Replacing the existing technologies with innovative and eco-efficient technologies can contribute to an added value increase in the production of new materials. Materials are one of the most dynamic and prospective fields, with applications in all other fields. The development of new advanced materials and technologies shall contribute to the procurement of a wide range of reliable products, with competitive prices and worldwide performance, high sensitivity and functionality, user-friendly and reduced energy consumption, for different industrial applications. Research in the field of advanced/intelligent materials supposes a fundamental, experimental, laboratory and technological research and its approach has to be linked to the application. This involves, even for the niche fields, complex projects which result in scientific issues in top journals, patents and functional models. The third edition of ModTech International Conference was held in Mamaia, Romania, between June 17-20, with the Professional Association in Modern Manufacturing Technologies, ModTech, as main organizer, and the Constanta Maritime University, Constanta, Romania, Silesian University of Technology, Gliwice, Poland, the Technical University of Chisinau, Republic of Moldova and the Donetsk National Technical University, Donetsk, Ukraine as co-organizers. The ModTech2015 International Conference brought together representatives of technology and materials manufacturers, various universities, professional associations and research institutes that exchanged the latest knowledge on the conference topics. This edition was

  6. Knowledge acquisition and creation in the high-tech industry

    Directory of Open Access Journals (Sweden)

    Juliano Pavanelli Stefanovitz

    2007-10-01

    Full Text Available This paper explores the new challenges that come with the emergence of knowledge-based approaches on organizational studies. It is widely recognized, in this context, the increasing importance of understanding the processes through which companys acquire, storage, disseminate and create knowledge. This research analysis the knowledge creation and external acquisition processes in the high-tech industry, environment in which intensive use of knowledge is made. For that, it presents a case study of an R&D Division of a company present in the industrial automation market. In recognition of its innovative competence, this company won the FINEP Prize – Technological Innovation. In this study, besides the identification of the main external knowledge sources, an analysis of the knowledge types conversion observed in its product development activities is made.

  7. Power quality in high-tech campus: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Moreno-Munoz, A.; Redel, M.; Gonzalez, M. [Universidad de Cordoba (Spain). Departamento de Electrotecnia y Electronica

    2006-07-01

    This paper presents preliminary results from a power-quality audit conducted at a high-tech campus over the last year. Voltage and current were measured at various R and D buildings; it was found that the main problems for the equipment installed were voltage sags and surges. The paper examines the causes and effects of power disturbances that affect computer or any other microprocessor-based equipment and analyses the auto-protection capabilities of modern power supplies. The convenience of 'enhanced power supply' or 'low-cost customer-side' protection solutions is also discussed. Finally, it addresses the role of the standards on the protection of electronic equipment and the implications for the final customer. (author)

  8. Advanced Polymeric Materials for High-tech Innovations

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@ High technology is advancing our society and modernizing our life and advanced materials play an important role in the technological innovations. My research group has been working on the development of advanced polymeric materials and in this talk I will report our recent work on the creation of new conjugated polymers with novel molecular structures and unique materials properties.1-18 Our work include the design of molecular structures of monomeric building blocks, development of stable, effective and environmentally benign "green” polymerization catalysts, discovery of new polymerization reactions, synthesis of functional macromolecules, fabrication of nanodimensional composites, assembly and control of hierarchical structures, and construction of electrooptical devices. We have revealed the liquid crystallinity, light emission, photoconductivity, optical limiting, nano-hybridization, solvatochromism, optical activity, self-organization, and biological activity of the linear polyacetylenes and hyperbranched polyarylenes. The utilization of the advanced polymers and their interesting materials properties for high-tech innovations will be discussed.

  9. Hi-tech products marketing and competitive advantage

    Directory of Open Access Journals (Sweden)

    Perović Jelena

    2004-01-01

    Full Text Available The company today, in causes turbulent environment and intensive integrations must cooperate, accept and develop high technology in order to achieve needs of customers. It's only way that companies replay on challenge global environment, decrease costs of investment per capita, decrease the risk, captivate new market and held competitive in causes of global market. High tech technology marketing function is help that results of new technology transfer on economy. Their function is reach need of customers, too. Positive influence of technology is the highest in area of production costs and productivity. Speed years are in front of our and it demands larger productivity, which primary source must be technology changes. High technology marketing is the most provocative framework for take competitive advantage, answer on global change and way of permanent reach rigorous need of customers.

  10. Emerging technologies in ANC at VAL-Virginia Tech

    Science.gov (United States)

    Johnson, Marty; Fuller, Chris; Homma, Kenji

    2003-10-01

    This presentation will overview the development and application of three new active noise control technologies at VAL-Virginia Tech. Distributed Active Vibration Absorbers (DAVAs) consist of large area spring elements with embedded active elements and covered with a dynamic mass layer. Development of conformal DAVAs and their application to noise control in aircraft and launch vehicle fairings will be overviewed. New work in applying active control techniques to developing virtual acoustic systems and its application to virtual prototyping and virtual reality applications will be discussed. The development a modular, compact active noise control duct which utilizes very small active sources, transducers and a cost effective controller to reducing the total radiated sound from small fans will be presented. The application of the modular ANC duct to a small computer cooling fan will be presented.

  11. Research on the competitiveness of high-tech industries in northeast China

    Science.gov (United States)

    Liu, Lei; Wang, Yang; Wang, Ming-Quan; Xiao, Yan-Bo; Gao, Ming

    2017-06-01

    Based on characteristics of high-tech industry in Northeast China, high-tech industry competitiveness index system was developed, and the competitiveness of high-tech industry was evaluated through principal component analysis and location quotient method. The results showed that the scale of high-tech industry in Northeast China as a whole was small, and presented a decreasing trend for the proportion in the country. The competitiveness of high-tech industry in Northeast China lagged far behind that of the eastern and central regions. The high-tech industry competitiveness of Liaoning, Jilin and Heilongjiang provinces in China ranked 15, 19 and 21, respectively. The manufacture of medicine in Jilin province, and the manufacture of aircraft and spacecraft and the related equipment in Liaoning and Heilongjiang provinces had high competitive advantage, but the manufacture of electronic equipment and communication equipment and the manufacture of computers and office equipment was lack of competitiveness. The development suggestions were put forward to improve the competitiveness of high-tech industries in Northeast China.

  12. Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities.

    Science.gov (United States)

    Glauser, Daniel L; Seyffert, Michael; Strasser, Regina; Franchini, Marco; Laimbacher, Andrea S; Dresch, Christiane; de Oliveira, Anna Paula; Vogel, Rebecca; Büning, Hildegard; Salvetti, Anna; Ackermann, Mathias; Fraefel, Cornel

    2010-04-01

    Adeno-associated virus (AAV) has previously been shown to inhibit the replication of its helper virus herpes simplex virus type 1 (HSV-1), and the inhibitory activity has been attributed to the expression of the AAV Rep proteins. In the present study, we assessed the Rep activities required for inhibition of HSV-1 replication using a panel of wild-type and mutant Rep proteins lacking defined domains and activities. We found that the inhibition of HSV-1 replication required Rep DNA-binding and ATPase/helicase activities but not endonuclease activity. The Rep activities required for inhibition of HSV-1 replication precisely coincided with the activities that were responsible for induction of cellular DNA damage and apoptosis, suggesting that these three processes are closely linked. Notably, the presence of Rep induced the hyperphosphorylation of a DNA damage marker, replication protein A (RPA), which has been reported not to be normally hyperphosphorylated during HSV-1 infection and to be sequestered away from HSV-1 replication compartments during infection. Finally, we demonstrate that the execution of apoptosis is not required for inhibition of HSV-1 replication and that the hyperphosphorylation of RPA per se is not inhibitory for HSV-1 replication, suggesting that these two processes are not directly responsible for the inhibition of HSV-1 replication by Rep.

  13. Treatment with lenalidomide (Revlimid®), cyclophosphamide (Endoxan®) and prednisone (REP) in relapsed/refractory multiple myeloma patients: results of a single centre retrospective study.

    Science.gov (United States)

    Zelis, N; Devos, T; Dierickx, D; Janssens, A; Raddoux, J; Verhoef, G; Delforge, M

    2014-04-01

    Lenalidomide (Revlimid®) combined with intermittent dexamethasone (the RD regimen) is one of the current standards for treatment of patients with relapsed/refractory multiple myeloma (MM). However, since the disease in the majority of patients will become resistant to RD, or treatment with RD needs to be discontinued due to side effects, we evaluated the combination lenalidomide, low-dose oral cyclophosphamide, with prednisone (REP) in patients with relapsed/refractory MM previously exposed to RD. For this purpose, we performed a single centre retrospective study of the efficacy of REP in 19 patients with relapsed/refractory MM. Overall response rate (partial response or better) with REP was 68% compared with 83% with RD, but with a shorter time to response with the triplet REP. Time to progression after REP was 6 months. Overall the REP regimen was better tolerated compared to RD. We conclude that the REP regimen is an effective treatment regimen for patients with relapsed/refractory MM with good tolerance, warranting further exploration in prospective randomized trials.

  14. Several Theoretical Issues on Agricultural Sci-tech Service and Management

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    In view of particularity and complexity of agricultural sci-tech service and management,this paper presents definition of basic concept of agricultural sci-tech service and management,sums up its basic characteristics,and discusses and analyzes its structural elements and functions. The agricultural sci-tech service and management plays an important role in speeding up rural construction and narrowing the gap between urban and rural areas. It ensures benign cycle of scientific and technological achievements and regional environment,and promotes development of agricultural industrialization.

  15. [The development of strategic management of high-tech surgical medical care].

    Science.gov (United States)

    Nechaev, V S; Krasnov, A V

    2013-01-01

    The high-tech surgical medical care is one of the most effective types of medical care in Russia. However high-tech surgical treatment very often is inaccessible for patients. The development of basics of strategic management of high-tech surgical care makes it possible to enhance availability of this type of care and to shorten the gap between volumes of rendered care and population needs. This approach can be resulted in decrease of disability and mortality of the most prevalent diseases of cardio-vascular diseases, malignant neoplasms, etc. The prerequisites can be developed to enhance life quality and increase longevity of population.

  16. The FinTech phenomenon: antecedents of financial innovation perceived by the popular press

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    The financial industry has been strongly influenced by digitalization in the past few years reflected by the emergence of “FinTech,” which represents the marriage of “finance” and “information technology.” FinTech provides opportunities for the creation of new services and business models and poses challenges to traditional financial service providers. Therefore, FinTech has become a subject of debate among practitioners, investors, and researchers and is highly visible in the popular media. ...

  17. The People's Republic of China's high-tech exports: Myth and reality

    OpenAIRE

    Xing, Yuqing

    2012-01-01

    Trade statistics portray the People's Republic of China (PRC) as the largest exporter of high-tech products. In this paper I will argue that the PRC's leading position in high-tech exports is a myth created by outdated trade statistics which are inconsistent with trade based on global supply chains. Current trade statistics mistakenly credit entire values of assembled high-tech products to the PRC, thus greatly inflating its exports. In 2009, the PRC's value-added accounted for only about 3% ...

  18. China s Imp.& Exp.of New and High-tech Products

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Import of New and High-tech Products Increases Rapidly The proportion of new and high-tech products in the total import continues to increase.Ever since 1991,the proportion of new and high-tech products in the total import has experienced a continuous growth.It took up only 14.8% of the total import in 1991.The figure reached 20.8% in 1998,and further rose to that of 26.3% in 2001.From January to June this year,the import of new and hightech products totaled 34.540 billion USD,up 18.1% over the same per...

  19. Is there a large-country advantage in high-tech?

    OpenAIRE

    Jan Fagerberg

    1995-01-01

    High-tech is a commonly used catch-word for industries that use a relatively large share of their resources on R&D and develop many new products and processes. It is a widely held view that high- tech is good for growth, and that countries that succeed in high- tech industry perform well. Schumpeterian theory, as well as the more recent “new growth” theories, are often quoted in support of this view. However, the “new growth” theories also suggest that large countries are more likely than sma...

  20. Baza danych BazTech – integracja i poszerzanie dostępu

    OpenAIRE

    2014-01-01

    The BazTech database – integration and widening access. The BazTech base enables the access to scientific publications in Polish journals in the field of technical sciences, and as one of the resources of open science is available at the Virtual Library of Science. The paper presents the current state of BazTech as an introduction to the review of the development of the base in the direction of integration with other resources. Integration – apart from multibrowsers (eg PRIMO), data aggregato...

  1. The FinTech phenomenon: antecedents of financial innovation perceived by the popular press

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    The financial industry has been strongly influenced by digitalization in the past few years reflected by the emergence of “FinTech,” which represents the marriage of “finance” and “information technology.” FinTech provides opportunities for the creation of new services and business models and poses challenges to traditional financial service providers. Therefore, FinTech has become a subject of debate among practitioners, investors, and researchers and is highly visible in the popular media. ...

  2. El montaje de la transición argentina. Un análisis de los films La República perdida, La República perdida II y Evita, quien quiera oír que oiga

    Directory of Open Access Journals (Sweden)

    Paola Judith Margulis

    2012-01-01

    Full Text Available El presente artículo se propone reconstruir una zona de la historia del documental argentino a partir del abordaje de tres films que tuvieron un alto impacto en Argentina hacia la transición democrática: La República perdida (Miguel Pérez, 1983, su secuela La República perdida II (Miguel Pérez, 1986 y Evita, quien quiera oír que oiga (Eduardo Mignogna, 1984. Dada la importancia de estos films -tanto en términos políticos como de impacto en el público-, intentaremos situarlos en contexto y analizar algunos aspectos inherentes a su lógica fílmica.

  3. Lecturas de un sueño. (Sobre la República literaria de Saavedra Fajardo

    Directory of Open Access Journals (Sweden)

    Rodríguez, Juan Carlos

    2013-12-01

    Full Text Available The author of the República Literaria, a diplomatic voyager from the 17th Century, dreams of a city of paper: to read a city as if it were a book and to read a book as if it were a journey throughout literary history. Is it possible? On this journey across all of written culture that Saavedra describes, where the inhabitants of the city are authors of ‘literary’ texts and the arts live together with the sciences and the muses, the author analyses with subtle irony the present and the tradition of everything that surrounds the production of all that is written. With the classic resource of the ‘Dream’ he shows an incredibly clear panorama where we can recognize the beginnings of capitalism, in which books have gone from being considered repositories of wisdom and common sense, to becoming mere marketplace objects.El autor de la República Literaria, un diplomático viajero del siglo XVII, sueña una ciudad de papel: leer una ciudad como si fuera un libro y leer un libro como si fuera un viaje a través de la historia literaria. ¿Es posible? En este recorrido por toda la cultura escrita que traza Saavedra, donde los habitantes de la ciudad son los autores de los textos «literarios» y las artes conviven con las ciencias y las musas, el autor desmenuza con finísima ironía la actualidad y la tradición de todo lo que rodea a la producción de lo escrito. Con el clásico recurso del «Sueño» muestra un panorama increíblemente nítido donde podemos reconocer los inicios del capitalismo en el que los libros han pasado de ser considerados como un depósito de sabiduría y cordura a tener carácter de mero objeto de mercado.

  4. Tech-X发动机及其先进技术分析%Analysis on Tech-X Engine and Its Advance Technology

    Institute of Scientific and Technical Information of China (English)

    李杰; 巨亚斌

    2013-01-01

      Tech-X发动机是GE公司研发的用于超大航程公务机的新一代高涵道比涡扇发动机。本文就Tech-X发动机的性能指标和先进技术创新进行了概括性分析,供相关人士参考。%The Tech-X is a high bypass turbofan engine currently under development by GE Aviation. It is being developed in paral el with the larger CFM International LEAP-X, and includes many similar technologies, like blisks and NOx reducing combustors. GE sees potential in using the engine both on large cabin business jets and regional aircraft, where it wil replace the CF34 in GE's production line.

  5. Virginia Tech Corps of Cadets alumnus Timothy Dillera named Hokie Hero

    OpenAIRE

    Cox, Carrie

    2009-01-01

    Corps of Cadets alumnus Capt. Timothy Dillera, United States Air Force, who received a degree in chemistry from the College of Science in 2003 has been selected as the Hokie Hero for the Virginia Tech versus Boston College football game.

  6. Virginia Tech structural engineer part of a winning design team for unusual corporate headquarters

    OpenAIRE

    Steeves, Sue

    2010-01-01

    The American Institute of Steel Construction has presented a national award to a design team, including a Virginia Tech structural engineer, for its work on a dramatic cantilevered corporate headquarters building in Michigan.

  7. Virginia Tech part of $14 million National Science Foundation nanotechnology grant

    OpenAIRE

    Doss, Catherine

    2008-01-01

    Researchers from geosciences and civil and environmental engineering at Virginia Tech are part of a consortium of four principal universities and five other schools awarded a multi-million dollar grant to study nanotechnology and the environment.

  8. Hi-tech Researches Speed up Scientific and Technological Innovations of CNOOC

    Institute of Scientific and Technical Information of China (English)

    Dong Weiliang; Wang Weiyuan

    2007-01-01

    @@ The scientific and technological development of CNOOC Limited entered a new stage during the Tenth Five-Year Plan period. High-tech researches in the company have catalyzed the technological innovation of the offshore petroleum industry.

  9. FRIDAY: EPA Administrator Visiting Georgia Tech to Discuss Manufacturing Innovation and Environmental Sustainability

    Science.gov (United States)

    ATLANTA - On Friday, EPA Administrator Gina McCarthy will visit Georgia Tech to speak about the connection between manufacturing innovation and environmental sustainability. McCarthy will meet with more than 50 high school students and faculty parti

  10. Definition of a short-cut methodology for assessing earthquake-related Na-Tech risk.

    Science.gov (United States)

    Busini, Valentina; Marzo, Enrico; Callioni, Andrea; Rota, Renato

    2011-08-15

    Na-Tech (Natural and Technological) refers to industrial accidents triggered by natural events such as storms, earthquakes, flooding, and lightning. Herein, a qualitative methodology for the initial assessment of earthquake Na-Tech risk has been developed as a screening tool to identify which situations require a much more expensive Quantitative Risk Analysis (QRA). The proposed methodology, through suitable Key Hazard Indicators (KHIs), identifies the Na-Tech risk level associated with a given situation (i.e., a process plant located in a given territory), using the Analytical Hierarchy Process as a multi-criteria decision tool for the evaluation of such KHIs. The developed methodology was validated by comparing its computational results with QRA results that involved Na-Tech events previously presented in literature.

  11. Kalam's visit to cement Indo-Swiss ties in high tech area

    CERN Multimedia

    Sumir, Paul

    2005-01-01

    Seeking to boost Indo-Swiss cooperation in high tech areas, President APJ Abdul Kalam arrived in Geneva on a four-day visit to Switzerland aimed at firming up plans for future cooperation with the CERN

  12. Virginia Tech mourns the loss of Dr. Bernard "Bernie" F. Feldman

    OpenAIRE

    Owczarski, Mark

    2004-01-01

    Bernard "Bernie" F. Feldman of Check, Va., professor of biomedical sciences and pathobiology in the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech , was killed in an automobile accident Feb. 19.

  13. The Trail Inventory of Bayou Teche National Wildlife Refuge [Cycle 1

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to create a baseline inventory of all non-motorized trails on Bayou Teche National Wildlife Refuge. Trails in this inventory are...

  14. Violence-prevention summit at Virginia Tech tackles bullying, gender-based violence, more

    OpenAIRE

    2010-01-01

    Bullying in schools, aggression in the workplace, violence against women -- all are complex problems. On Nov. 12 and 13, Virginia Tech hosts a gathering to make recommendations about violence prevention.

  15. High-Tech Blood Sugar Monitors May Help People with Type 1 Diabetes

    Science.gov (United States)

    ... gov/news/fullstory_163211.html High-Tech Blood Sugar Monitors May Help People With Type 1 Diabetes ... need insulin shots every day manage their blood sugar levels safely, two new studies suggest. Also known ...

  16. Technology for Tomorrow---High-Tech Exhibition Held in HONG KONG

    Institute of Scientific and Technical Information of China (English)

    Fang Lin

    1997-01-01

    @@ "Technology for Tomorrow"--- High-Tech Exhibition has been held by Hong Kong Science & Technology Sector for Celebration of Return of Sovereignty Association and China Association Science & Technology on June 28 to July 4, 1997 in Hong Kong.

  17. Virginia Tech's Ashley White named to USA Today All-USA First Team

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    Virginia Tech senior Ashley White, a University Honors student pursuing degrees in both materials science and engineering and music performance, has been named to USA Today's All-USA College Academic First Team.

  18. Virginia Tech team qualifies as DARPA Urban Challenge semi-finalist

    OpenAIRE

    Crumbley, Liz

    2007-01-01

    "VictorTango," a team of Virginia Tech engineering and geography students, will travel to Victorville, Calif., for the national qualifying rounds of the Urban Challenge autonomous vehicle competition, sponsored by the Defense Advanced Research Projects Agency (DARPA).

  19. FDA OKs High-Tech Diabetes Device to Help Replace Fingerstick Tests

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_162638.html FDA OKs High-Tech Diabetes Device to Help Replace ... too low, and potentially incorrect insulin dosing, the FDA said. The Dexcom G5 is the first continuous ...

  20. Comparative Analysis of Capital Productivity in China's High-Tech Industries

    Institute of Scientific and Technical Information of China (English)

    LingWang; AdamSzirmai

    2005-01-01

    While labor productivity is a topic of constant debate and has been studied extensively, far less attention has been devoted to the question of capital productivity. Productive use of physical capital is an important source of economic growth and investment return. This paper presents a comparative study of capital productivity in China's high-tech industry. Using a version of the perpetual inventory method (PIM), new estimates have been made of the physical capital stock by sector. Capital productivity in China's high-tech industry is higher than in total manufacturing, but the gap between them has been shrinking. Comparison with high-tech industries in the US., highlights that China's high-tech industries could play a more important role in the growth of manufacturing and the whole economy.

  1. Maya Angelou to speak during Virginia Tech's third annual Martin Luther King Jr. celebration

    OpenAIRE

    Williams, Meghan

    2008-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  2. Maya Angelou to visit Virginia Tech during third annual Martin Luther King, Jr. celebration

    OpenAIRE

    Williams, Meghan

    2007-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  3. Biomedical Engineering Bionanosystems Research at Louisiana Tech University

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, James; Lvov, Yuri; Hegab, Hisham; Snow, Dale; Wilson, Chester; McDonald, John; Walker, Lynn; Pratt, Jon; Davis, Despina; Agarwal, Mangilal; DeCoster, Mark; Feng, June; Que, Long; O' Neal, Chad; Guilbeau, Eric; Zivanovic, Sandra; Dobbins, Tabbetha; Gold, Scott; Mainardi, Daniela; Gowda, Shathabish; Napper, Stan

    2010-03-25

    The nature of this project is to equip and support research in nanoengineered systems for biomedical, bioenvironmental, and bioenergy applications. Funds provided by the Department of Energy (DoE) under this Congressional Directive were used to support two ongoing research projects at Louisiana Tech University in biomedical, bioenvironmental, and bioenergy applications. Two major projects (Enzyme Immobilization for Large Scale Reactors to Reduce Cellulosic Ethanol Costs, and Nanocatalysts for Coal and Biomass Conversion to Diesel Fuel) and to fund three to five additional seed projects were funded using the project budget. The project funds also allowed the purchase and repair of sophisticated research equipment that will support continued research in these areas for many years to come. Project funds also supported faculty, graduate students, and undergraduate students, contributing to the development of a technically sophisticated work force in the region and the State. Descriptions of the technical accomplishments for each funded project are provided. Biofuels are an important part of the solution for sustainable transportation fuel and energy production for the future. Unfortunately, the country's appetite for fuel cannot be satisfied with traditional sugar crops such as sugar cane or corn. Emerging technologies are allowing cellulosic biomass (wood, grass, stalks, etc.) to also be converted into ethanol. Cellulosic ethanol does not compete with food production and it has the potential to decrease greenhouse gas (GHG) emissions by 86% versus current fossil fuels (current techniques for corn ethanol only reduce greenhouse gases by 19%). Because of these advantages, the federal government has made cellulosic ethanol a high priority. The Energy Independence and Security Act of 2007 (EISA) requires a minimum production of at least 16 billion gallons of cellulosic ethanol by 2022. Indeed, the Obama administration has signaled an ambitious commitment of achieving

  4. Pleonexía: el centro ausente de La República de Platón

    OpenAIRE

    Carrasco, Nemrod

    2008-01-01

    La pleonexía es una categoría platónica más complicada de lo que puede parecer. Tradicionalmente asociada a las posiciones de Calicles y Trasímaco, lo primero que nos indica La república es que la pleonexía no es únicamente el motor constitutivo de toda ciudad, sino el punto de referencia decisivo de la concepción platónica de la justicia. Es ahí donde radica la paradoja del tránsito de la ciudad sana de Sócrates a la ciudad enferma de Glaucón: lejos de rep...

  5. Liberalismo, iluminismo y romanticismo: el problema de la libertad en dos novelas de la República Restaurada

    Directory of Open Access Journals (Sweden)

    Verónica Hernández Landa Valencia

    2016-07-01

    Full Text Available El artículo propone una reflexión en torno a la forma como influyen tres corrientes de pensamiento, el liberalismo, el iluminismo y el romanticismo, en la representación del problema de la libertad en dos novelas históricas publicadas en la República Restaurada: Monja y casada, virgen y mártir, de Vicente Riva Palacio, y El pecado del siglo, de José Tomás de Cuéllar. Se busca mostrar que dichas corrientes se entrecruzan en un solo texto, que ello contribuye a la conformación de un concepto de libertad restringida y que la forma específica que adquiere ese concepto se explica a partir de la postura ideológica y política de los autores en el contexto de la República Restaurada.

  6. 150 años despues: Constitución de la república de Tunja

    Directory of Open Access Journals (Sweden)

    José Hurtado García

    1961-12-01

    Full Text Available En Tunja perduran abiertos los corazones y los zaguanes. La Villa noble de Suárez Rendón, embelesada en el canto de la Madre Castillo y de don Juan de Castellanos, amaneció en la República con el sacrificio de sus hijos y con sus ideas proceras. Precisamente en este mes de diciembre de 1961 -el nueve- se cumplen los ciento cincuenta años de la expedición de su Constitución, cuyo título definido reza: " Constitución de la República de Tunja sancionada en plena Asamblea de los Representantes de toda la Provincia, en sesiones continuas desde el 21 de noviembre hasta el 9 de diciembre de 1811. Año Segundo de la Transformación Política del Nuevo Reyno de Granada".

  7. A “Primeira República”: os preceitos liberais e a práxis oligárquica

    Directory of Open Access Journals (Sweden)

    Flávia Liziane Gonzáles Bandeira

    2009-04-01

    Full Text Available O presente artigo visa a analisar o processo de mudança de regime político no Brasil, no final do século XIX – o advento da República. As fontes utilizadas da análise são um fragmento da primeira Constituição republicana e os programas dos partidos Republicano Federal e Republicano Conservador. Visou-se a buscar os limites entre o discurso encontrado nesses documentos e a prática política realizada no Brasil da República Velha. Para melhor extrair o teor do documento foi utilizada a técnica metodológica de análise de conteúdo quantitativa, nomeando unidades referenciais mais incidentes nos respectivos textos, seguida da análise qualitativa aplicada a estas.

  8. U.S. Army flyover hosted by the Virginia Tech Corps of Cadets Friday and Saturday

    OpenAIRE

    2008-01-01

    The Virginia Tech Corps of Cadets and the Army ROTC Department will sponsor, barring weather or operational factors, a military aircraft flyover with two AH-64 Apache attack helicopters from the Combat Aviation Brigade of the 82nd Airborne Division from Fort Bragg, N.C., during pre-game ceremonies of the Virginia Tech vs. Western Kentucky University football game to be held Saturday, Oct. 4.

  9. Definition of a shortcut methodology for assessing flood-related Na-Tech risk

    OpenAIRE

    Marzo, E.; Busini, V.; Rota, R.

    2012-01-01

    In this paper a qualitative methodology for the initial assessment of flood-related Na-Tech risk was developed as a screening tool to identify which situations require a much more expensive quantitative risk analysis (QRA). Through the definition of some suitable key hazard indicators (KHIs), the proposed methodology allows the identification of the Na-Tech risk level associated with a given situation; the analytical hierarchy process (AHP) was used as a multi-criteria decis...

  10. Sieciowe usługi informacyjne dla nauk technicznych : BazTech, BazTOL

    OpenAIRE

    2007-01-01

    The paper presents the current state and plans for development of the BazTech "Polish Technical Journals Contents" database. It is created by 22 academic libraries and centers for scientific information. The project is coordinated by the Cracow University of Technology. The Baz Tech database, situated at http://baztech.icm.edu.pl (ICM UW server), within the framework of the project "Virtual Scientific Library" lists over 400 journals. The paper also describes the assumptions for the creation ...

  11. Problems and Countermeasures of Zhejiang High-Tech Enterprises Industry-University-Institute Cooperation in China

    Science.gov (United States)

    Zhou, Qing; Mao, Chong-Feng; Hou, Lin

    Industry-university-institute cooperation is an important means to accelerate technical development and achievements for high-tech enterprises. Considering that Zhejiang high-tech enterprises existed some problems which included low cooperative level, single distribution, weak secondary R&D ability, obvious risk and so on, government should play an guiding role on improving information service system, enhancing cooperative level, promoting scientific intermediary service organization system construction, and building better environment for Industry-university-institute cooperation.

  12. HI-TECH BUSINESS IN ECONOMICALLY DEVELOPED COUNTRIES AND ITS INTEGRATION MECHANISM

    Directory of Open Access Journals (Sweden)

    V. N. Voronina

    2011-01-01

    Full Text Available In the hi-tech sphere, business integration forms widely wary. Particularly interesting is a way of such integration practiced in Japan through associations called «keiretsu» whose functioning mechanism is considered in detail. Specific features of this approach make it advantageous incomparison to classic western firm integration ways. Still, experiences gained in USA and some European countries, particularly in Finland, are of interest for Russian hi-tech business too.

  13. O sistema oligárquico representativo da Primeira República

    Directory of Open Access Journals (Sweden)

    Wanderley Guilherme dos Santos

    2013-03-01

    Full Text Available Entre les absolutismes des XVIIe et XVIIIe siècles, d'une part, et les variantes démocratiques repérées après la Seconde Guerre Mondiale, d'autre part, demeure un brouillard conceptuel gênant la compréhension de l'histoire politico-institutionnelle de cette période. L'oligarchie, traitée soit comme germe de démocratie soit comme vestige autocratique, reste une période soumise à la subjectivité. On présente un modèle analytique différent de ce que serait un système oligarchique, à la validité trans-locale, en cherchant à montrer la façon dont l'histoire du Second Empire et de la Première République apparaitrait au moyen d'une approche préalable utilisant le modèle général.

  14. Desterrando formas poéticas en la República de Platón.

    Directory of Open Access Journals (Sweden)

    Sergio Ariza.

    2009-12-01

    Full Text Available Este artículo examina un aspecto seminal, pero sorprendente en la crítica de Platón de la poesía: Platón destierra a los contenidos, no sólo particular, y los autores, pero las formas poéticas también ellas mismas, en concreto la forma mimética. El análisis muestra que la principal razón para desterrar tales reside en el hecho de que Platón descubrió que la forma como la forma (con independencia de su contenido tiene un carácter autónomo y se rige por criterios estéticos y no moral. Estos criterios estéticos son incompatibles con la ideología que apoya la polis ideal. Esto pone de relieve el mérito del análisis de Platón de que no está en la evaluación de la actividad poética, sino en la identificación de las puramente estéticas y sus consecuencias sobre el programa político de la República

  15. Leptospirosis porcina: prevalencia serológica en establecimientos productores de la República Argentina

    Directory of Open Access Journals (Sweden)

    Jessica Petrakovsky M.

    2013-03-01

    Full Text Available Objetivo. Detectar la presencia de anticuerpos contra Leptospira sp en cerdos que no presentaban sintomatología clínica, pertenecientes a establecimientos de producción porcina ubicados en todo el territorio de la República Argentina. Materiales y métodos. La asignación de predios y muestras se realizó en forma proporcional a los registrados en cada provincia a lo largo de todo el país. En total se estudiaron 1.524 predios, de los cuales se tomaron 19.872 muestras de suero y en la primera etapa se procesaron 3.631 de los mismos. Este estudio toma en consideración zonas identificadas por provincia, municipio y predios. Los sueros fueron analizados por la técnica de MAT (prueba de microaglutinación. Resultados. El 30% de las muestras resultaron positivas a la prueba tamiz empleada (primera etapa del MAT. La mayoría presentó coaglutininas a dos o a tres serovariedades. Al realizar la titulación de los sueros (segunda etapa del MAT, el porcentaje de positividad se mantuvo, siendo los serovares de mayor prevalencia Castellonis e Icterohaemorrhagiae. El 90% de las muestras presentó un título final de 1:200. Conclusiones. La existencia de sueros positivos en todas las provincias indica el contacto de los animales con la leptospira a lo largo de todo el país.

  16. Representações cômicas da República no contexto do Getulismo

    Directory of Open Access Journals (Sweden)

    Elio Chaves Flores

    2001-01-01

    Full Text Available Neste artigo analiso as representações cômicas e discursivas da República e a trajetória política de Getúlio Vargas, a partir de uma narrativa que se assenta no método regressivo. Para isso, trabalhei com uma série de caricaturas publicadas em jornais e revistas na duração entre 1930 e 1954, confrontando a intertextualidade dessas imagens com alguns discursos satíricos e irônicos produzidos por memorialistas. Procuro demonstrar que há semelhança entre a inversão humorística e a textualidade da memória, quando inventam a respeito de seu tempo e dos outros imagens verossímeis.This article analyses the comic and discursive representations of the Brazilian Republic and Getúlio Vargas’ political career, starting from a narrative constructed in the regressive method. For that, I worked with a series of cartoons published in newspapers and magazines in the span of time between 1954 and 1930, matching the intertextuality of these images with some of the satiric and ironic speeches produced by witnesses. It is demonstrated there is likeness between the comic inversion and the textuality of the memory, when they invent concerning their time and other ones, the verisimilitude of the images.

  17. A loucura e a república no Brasil: a influência das teorias raciais

    Directory of Open Access Journals (Sweden)

    Audrey Rossi Weyler

    2006-03-01

    Full Text Available O presente artigo tem como objetivo discutir as modificações nas formas de compreensão e de enfrentamento da loucura na passagem do Império para a República, levando-se em conta a influência das teorias raciais importadas da Europa a partir de 1870. A adoção desses modelos teóricos cumpriu uma série de funções sociais e políticas referente a um projeto de nação. Neste contexto, as manifestações da loucura passaram a ser associadas à doença, à degeneração e ao risco e sofreram variadas medidas de opressão justificadas "cientificamente". Até hoje, as interpretações científicas do problema da "doença mental" continuam localizando a enfermidade no paciente. Ao reduzir a doença e a sua causa a uma problemática exclusivamente pessoal, sem que se considere o contexto socioeconômico e político da sua emergência, estas explicações configuram-se como ideologia.

  18. Les revistes bilingües a la Tortosa de la II República

    Directory of Open Access Journals (Sweden)

    M. Carme Gombau Domingo

    2016-06-01

    Full Text Available En l’àmbit de la premsa tortosina en català del primer terç del segle xx es donen dues actituds lingüístiques: la fabriana i la tortosinista. La primera, partidària del model de llengua de l’IEC, era minoritària als anys vint però es generalitza a partir dels anys trenta (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita; mentre que el tortosinisme, que es correspon amb una ideologia cada cop més localista i que eleva el «parlar tortosí» a la categoria de llengua, queda reduït durant la II República a tres revistes bilingües: La Zuda, Germanor i La Santa Cinta. There were two linguistic actitudes in the tortosine press of the first third in the 20th century: the fabriana amb the tortosinista. The fabriana, in favour of the IEC linguistic model, was in minority during the 20’s, but it became widespread from the 30’s (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita. The second, the tortosinista, had a local ideology and compared the tortosinisme talk as a complet language, but it was reduced during the ii Republic to three magazines: La Zuda, Germanor i La Santa Cinta.

  19. Interspecies extrapolation based on the RepDose database--a probabilistic approach.

    Science.gov (United States)

    Escher, Sylvia E; Batke, Monika; Hoffmann-Doerr, Simone; Messinger, Horst; Mangelsdorf, Inge

    2013-04-12

    Repeated dose toxicity studies from the RepDose database (DB) were used to determine interspecies differences for rats and mice. NOEL (no observed effect level) ratios based on systemic effects were investigated for three different types of exposure: inhalation, oral food/drinking water and oral gavage. Furthermore, NOEL ratios for local effects in inhalation studies were evaluated. On the basis of the NOEL ratio distributions, interspecies assessment factors (AF) are evaluated. All data sets were best described by a lognormal distribution. No difference was seen between inhalation and oral exposure for systemic effects. Rats and mice were on average equally sensitive at equipotent doses with geometric mean (GM) values of 1 and geometric standard deviation (GSD) values ranging from 2.30 to 3.08. The local AF based on inhalation exposure resulted in a similar distribution with GM values of 1 and GSD values between 2.53 and 2.70. Our analysis confirms former analyses on interspecies differences, including also dog and human data. Furthermore it supports the principle of allometric scaling according to caloric demand in the case that body doses are applied. In conclusion, an interspecies distribution animal/human with a GM equal to allometric scaling and a GSD of 2.5 was derived.

  20. República federal y patronato: el ascenso y descalabro de un proyecto

    Directory of Open Access Journals (Sweden)

    Brian Connaughton

    2010-06-01

    Full Text Available Este artículo aborda el patronato durante la primera república federal (1824-1834 desde la perspectiva de los debates que lo rodearon y dificultaron una solución por la cual el gobierno mexicano ejerciera los derechos de patrono de la Iglesia. La polémica sobre el patronato tuvo aspectos eclesiológicos, políticos y diplomáticos. Permite ver que México estaba inserto en una compleja dinámica nacional e internacional que acabaría frustrando la firma de un concordato.This article examines the trust established during the first federal republic (1824-1834 from the perspective of the debates that surrounded it and prevented reaching a solution whereby the Mexican government would act as owner of the Church. The polemic over the trust had ecclesiastic, political and diplomatic aspects. It showed that Mexico was inserted in a complex national and international dynamic that would end up preventing the signing of a concordat.

  1. Sistema de salud de República Dominicana The health system of Dominican Republic

    Directory of Open Access Journals (Sweden)

    Magdalena Rathe

    2011-01-01

    Full Text Available En este trabajo se describen las condiciones de salud de la República Dominicana y, con mayor detalle, el sistema de salud dominicano, incluyendo su estructura y cobertura, sus fuentes de financiamiento, el gasto en salud, los recursos físicos, materiales y humanos de los que dispone, las tareas de rectoría que desarrolla el Ministerio de Salud Pública y la generación de información. También se discuten la participación de los usuarios en la operación y evaluación del sistema de salud y las más recientes innovaciones implementadas, dentro de las que destacan la nueva Ley General de Salud, la nueva Ley de Seguridad Social y el Plan Decenal de Salud.This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Public Health and the generation of health information. The participation of health care users in the operation and evaluation of the system and the most recent policy innovations, including the new General Health Law, the new Social Security Law and the Decennial Health Plan are also discussed.

  2. Mapa educativo nacional. Una experiencia en la República Argentina

    Directory of Open Access Journals (Sweden)

    Horacio Rodolfo Bozzano

    2006-01-01

    Full Text Available El Proyecto Mapa Educativo Nacional (MEN es un SIG generado a partir del desarrollo e integración de 24 Mapas Educativos Provinciales sobre la base de un modelo conceptual general, con una visión dinámica de los 49.000 establecimientos educativos, así como de su contexto territorial. Los objetivos del trabajo son: a sistematizar los aportes al Proyecto MEN desde la teoría cartográfica, reconociendo instancias de concepción, construcción y comunicación de los mapas que lo integran, así como vinculaciones entre territorio, espacio y espacialidades emergentes de la concreción de la tarea; y b identificar en qué medida la concreción del Proyecto MEN en la República Argentina contribuye a fortalecer un enfoque dialéctico conocimiento-realidad sobre el territorio y la gestión aplicado a un objeto de estudio e intervención concreto de desarrollo institucional, con el propósito de promover un círculo virtuoso de transformación entre sujetos de cambio y agentes de desarrollo.

  3. La Historia de la Psicología en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Josefina Zaite

    2013-01-01

    Full Text Available Este trabajo revisa el desarrollo de la psicología académica y profesional en la República Dominicana. Se da relevancia a los acontecimientos socio-históricos que sirvieron de contexto para el surgimiento y el avance de la psicología dominicana. Los aportes de los y las profesionales que contribuyen al impulso de los estudios y el ejercicio profesional de la psicología en nuestro país, son señalados y reconocidos. En el trabajo se aborda un análisis de los ámbitos de realización; así como de los logros y de las dificultades, en el avance tanto de la psicología académica, como del ejercicio profesional en la psicología dominicana. Finalmente, se consideran las perspectivas actuales de la psicología dominicana, para su desarrollo, su integración y proyección en el conjunto de la psicología en el Caribe y en Latinoamérica.

  4. K2 Warm Jupiters with the LCOGT TECH collaboration

    Science.gov (United States)

    Shporer, Avi; Bayliss, Daniel; Cochran, William D.; Colón, Knicole D.; Dragomir, Diana; Palle, Enric; Potter, Stephen; Siverd, Robert; LCOGT TECH Collaboration

    2016-06-01

    Many transiting gas giant planets on short orbital periods (so called hot Jupiters) have larger radii than theoretically expected. Although several explanations have been proposed, none have completely solved this puzzle. As the number of known transiting planets grew a correlation was identified between gas giant radius and the stellar incident flux. Still, it is not clear whether this correlation is causation. Several questions remain and answering them will characterize in more detail this observed correlation and in turn the process responsible for the inflated radii, such as: Is the lack of inflated warm Jupiters a robust feature? What is the incident flux below which there are no inflated gas giants? How low in incident flux does this correlation stretch? These questions arise since there are only a small number of transiting gas giants with low incident flux, below about 108 erg/s/cm2, corresponding to orbital periods of about 10 days and longer for a Sun-like host star. Discovering and confirming more transiting warm Jupiters is the goal of this project, undertaken by the LCOGT Transiting Exoplanet CHaracterization (TECH) team. We are using K2 as our main source of transiting warm Jupiter candidates, with a few candidates discovered in each K2 campaign. LCOGT telescopes are being used for obtaining additional ground-based transit light curves, which are critical for confirming and refining the K2 transit ephemeris as outliers during ingress or egress of the few transit events observed by K2 can bias the measured ephemeris. Further ground-based follow-up data, including spectroscopy, radial velocities, and high angular resolution imaging, are obtained by facilities directly accessible by LCOGT TECH team members. In addition, once LCOGT’s Network of Robotic Echelle Spectrographs (NRES) are deployed in the near future they will allow obtaining spectroscopy and radial velocities with LCOGT facilities. On top of studying the inflated hot Jupiter conundrum

  5. Dos nuevas publicaciones de la Biblioteca Luis Ángel Arango del Banco de la República

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1961-11-01

    Full Text Available La Biblioteca Luis-Ángel Arango, del Banco de la República, acaba de dar a la publicidad dos importantes trabajos que serán inapreciable ayuda para los investigadores de las letras colombianas, como son el volumen del Catálogo de su espléndida colección y Papeletas Bibliográficas para el estudio de la historia colombiana.

  6. Molecular Dynamics of Rab7::REP1::GGTase-II Ternary Complex and Identification of Their Putative Drug Binding Sites.

    Science.gov (United States)

    Sindhu, Meenakshi; Saini, Vandana; Piplani, Sakshi; Kumar, A

    2013-01-01

    The structure-function correlation of membrane proteins have been a difficult task, particularly in context to transient protein complexes. The molecular simulation of ternary complex of Rab7::REP1::GGTase-II was carried out to understand the basic structural events occurring during the prenylation event of Rab proteins, using the software YASARA. The study suggested that the C-terminus of Rab7 has to be in completely extended conformation during prenylation to reach the active site of RabGGTase-II. Also, attempt was made to find putative drug binding sites on the ternary complex of Rab7::REP1::GGTase-II using Q-SiteFinder programme. The comprehensive consensus probe generated by the program revealed a total of 10 major pockets as putative drug binding sites on Rab7::REP:: GGTase-II ternary complex. These pockets were found on REP protein and GGTase protein subunits. The Rab7 was found to be devoid of any putative drug binding sites in the ternary complex. The phylogenetic analysis of 60 Rab proteins of human was carried out using PHYLIP and study indicated the close phylogenetic relationship between Rab7 and Rab9 proteins of human and hence with further in silico study, the present observations can be extrapolated to Rab9 proteins. The study paves a good platform for further experimental verifications of the findings and other in silico studies like identifying the potential drug targets by searching the putative drug binding sites, generating pharmacophoric pattern, searching or constructing suitable ligand and docking studies.

  7. CARACTERIZACIÓN MOLECULAR MEDIANTE rep-PCR DE AISLADOS NATIVOS DE Bacillus thuringiensis, OBTENIDOS DE MUESTRAS DE SUELO

    Directory of Open Access Journals (Sweden)

    Fabi\\u00E1n Galvis

    2014-01-01

    Full Text Available Bacillus thuringiensis es una bacteria Gram-positiva formadora de esporas, que produ - ce cristales parasporales de naturaleza proteica, tóxicos contra diferentes órdenes de insectos y biodegradables e inocuos para otras especies. Esta investigación empleó el modelo experimen - tal, que mediante técnicas de observación permi - tió, la identificación microbiológica y bioquímica de B. thuringiensis a partir de muestras de suelo de los municipios de Cúcuta, El Zulia, Los Patios, San Cayetano y Villa del Rosario, Norte de Santander, Colombia, y su posterior caracteri - zación con los marcadores moleculares Bc-Rep y MB1. Se identificaron microbiológica y bioquí - micamente 10 aislados como B. thuringiensis ; los resultados del análisis filogenético mostraron diferencias significativas en los agrupamientos obtenidos con los marcadores Bc-Rep y MB1. Con Bc-Rep se registró un índice de similaridad bajo (18%, mientras que con el marcador MB1 se obtuvo un índice mayor de similitud, 58%. En este trabajo se evidenció una gran variabilidad genética entre los aislados, que mostraron a los marcadores Bc-Rep y MB1 como altamente efectivos para diferenciar cepas estrechamente relacionadas, convirtiéndose en una herramienta genética de gran valor para estudios de identifi-cación y diversidad en B. thuringiensis.

  8. Operación Sonrisa República Dominicana: 8 años de una intensa y positiva experiencia

    Directory of Open Access Journals (Sweden)

    Fernando De La Cruz-Acosta

    2016-03-01

    Full Text Available El objetivo de este artículo es dar a conocer el trabajo que, desde hace 8 años, está realizando un grupo de cirujanos plásticos perteneciente a la Fundación Operación Sonrisa República Dominicana a favor de los pacientes con malformaciones congénitas faciales, especialmente labio leporino y fisura palatina.

  9. Operación Sonrisa República Dominicana: 8 años de una intensa y positiva experiencia

    OpenAIRE

    Fernando De La Cruz-Acosta

    2016-01-01

    El objetivo de este artículo es dar a conocer el trabajo que, desde hace 8 años, está realizando un grupo de cirujanos plásticos perteneciente a la Fundación Operación Sonrisa República Dominicana a favor de los pacientes con malformaciones congénitas faciales, especialmente labio leporino y fisura palatina.

  10. La Segunda República Española: Acción y omisión en materia electoral

    Directory of Open Access Journals (Sweden)

    Enrique Cebrián Zazurca

    2016-01-01

    Full Text Available : El artículo realiza un recorrido por la normativa electoral vigente en la Segunda República Española; presenta las características principales de las distintas normas, resaltando los elementos del régimen electoral republicano. Una vez conocido el régimen, se abordan las principales claves del sistema electoral de la República concebido globalmente. Finalmente, el artículo pone en relación el sistema electoral con el sistema de partidos, tratando de valorar si aquel influyó en la crisis de la República. El trabajo sostiene que en la Segunda República Española no se aprobó nunca una ley electoral que pudiera considerarse como verdaderamente republicana.

  11. State support of the high-tech exports: comparative analysis and lessons for Ukraine

    Directory of Open Access Journals (Sweden)

    Yevgen Panchenko

    2016-12-01

    Full Text Available The nature of the natural increase in the share of high-tech exports in the overall world exports and trade in general is revealed. The trends in geographical and industrial developments of a high-tech exports in 2004-2015 are shown in the world, developed countries and the EU. Based on the study of dynamics of the high-tech exports of the leading countries in general, as well as engineering products segment, the basic models of state regulation in this sphere are identified i.e. active dirigisme, moderate dirigisme and liberalism. The experience of maintaining a high-tech exports to the US, Germany, Britain, Japan, South Korea and China is summarized. The tendencies of high-tech exports of Ukrainian enterprises in industries such as aerospace engineering, electronics and telecommunications, scientific instruments, computer and office appliances, as well as military industrial products were analyzed. The directions of forming the state support of domestic exporters of high-tech products were identified.

  12. El Ecoturismo en los Humedales: Análisis de las Potencialidades de República Dominicana

    Directory of Open Access Journals (Sweden)

    Francisco Orgaz Agüera

    2014-04-01

    Full Text Available El turismo se configura como uno de los principales motores económicos de República Dominicana. En este sentido, el turismo de sol y playa es la principal tipología turística en el país. Aunque, República Dominicana cuenta con numerosas potencialidades turísticas para poner en marchas nuevas formas de turismo: Turismo gastronómico, turismo ornitológico, turismo cultural, ecoturismo, etc. El principal objetivo de esta investigación es analizar las potencialidades existentes en República Dominicana para desarrollar el ecoturismo en las zonas de humedales. La metodología ha consistido en un trabajo de campo, a través de las entrevistas, los grupos de discusión y la observación participante. Los resultados muestran las grandes potencialidades que tiene el país para desarrollar el ecoturismo en los humedales, y contribuir así, al desarrollo socioeconómico de las comunidades locales. 

  13. Overview of the relativistic electron precipitations (REP) observed on LEO satellites and ISS by Bulgarian build instruments

    Science.gov (United States)

    Dachev, Tsvetan

    Relativistic electron precipitation (REP) are observed by the R3D B2/B3 and RD3-B3 instruments during the flights of the Foton M2/M3 and “BION-M” № 1 satellite in 2005, 2007 and 2013, and by the R3DE/R instruments at the EXPOSE-E facility of the European Columbus module and at the EXPOSE-R facility of the Russian Zvezda module of the International Space Station (ISS) in the period from February 2008 till August 2010. The obtained dose rates strongly depend by the external and internal shielding of the detectors in the instruments. The highest dose rate reaching more than 20 mGy h (-1) was observed outside the ISS Zvezda module during the REP in April 2010 being the second largest in GOES history with a >2 MeV electron fluence event. REP doses behind relatively thick shielding are too small but may play considerable role during extra vehicular activity (EVA) when the cosmonauts/astronauts body is shielded only by the space suit.

  14. Enhanced nicking activity of Rep in presence of pre-coat protein of Mungbean yellow mosaic India virus.

    Science.gov (United States)

    Rouhibakhsh, A; Choudhury, N R; Mukherjee, S K; Malathi, V G

    2012-04-01

    Yellow mosaic disease causes severe yield loss in grain legumes in Indian subcontinent and south east Asia. The disease is caused by two virus species, Mungbean yellow mosaic India virus (MYMIV) and Mungbean yellow mosaic virus (MYMV). They have genome organization typical of Old World begomoviruses, the unique feature being the presence of an open reading frame (ORF) AV2 upstream of coat protein gene. In order to elucidate its function, ORF AV2 of blackgram isolate, Mungbean yellow mosaic India virus-[India:New Delhi:Blackgram 3:1991] MYMIV-[IN:ND:Bg3:91] and cowpea isolate, Mungbean yellow mosaic India virus-[India:New Delhi:Cowpea7:1998] MYMIV-[IN:ND:Cp7:98], respectively, were over expressed in Escherichia coli in fusion with maltose binding protein (MBP). The recombinant protein did not show efficient binding to DNA. However, both MBP-BgAV2 and MBP-CpAV2 proteins modulated nicking and ATPase activity of replication initiation protein (Rep). Even low concentration, 20 ng of MBP-BgAV2 and MBP-CpAV2 could bring 20 folds increase in nicking activity of Rep. Similarly in the presence of AV2 protein, two to three fold increase in ATPase activity was observed. It is hypothesized that AV2 protein may play a role of accessory protein modulating Rep activities.

  15. Revolución versus reforma educativa en la segunda república española. Elementos de ruptura

    Directory of Open Access Journals (Sweden)

    Juan Manuel FERNÁNDEZ SORIA

    2010-03-01

    Full Text Available RESUMEN: Están fuera de toda duda las conexiones existentes entre la República de 1931-35 y la de 1936-39. En este sentido estamos de acuerdo con quienes afirman que el estallido de la guerra del 36 es el resultado de un proceso que arranca del mismo año en que se proclama la II República, iniciándose ya entonces —como sostiene Andrés M. Kramer— la «mecánica de guerra civil». La educación republicana en tiempo de guerra no puede quedar fuera de esta consideración, porque aquélla sumerge sus cimientos más profundos en la política educativa de 1931-35. Efectivamente, muchas de las acciones educativas y culturales llevadas a cabo durante la guerra no tendrían fácil explicación si no se examina previamente la tarea de la República del 31 en estos mismos aspectos.

  16. PrismTech Data Distribution Service Java API Evaluation

    Science.gov (United States)

    Riggs, Cortney

    2008-01-01

    My internship duties with Launch Control Systems required me to start performance testing of an Object Management Group's (OMG) Data Distribution Service (DDS) specification implementation by PrismTech Limited through the Java programming language application programming interface (API). DDS is a networking middleware for Real-Time Data Distribution. The performance testing involves latency, redundant publishers, extended duration, redundant failover, and read performance. Time constraints allowed only for a data throughput test. I have designed the testing applications to perform all performance tests when time is allowed. Performance evaluation data such as megabits per second and central processing unit (CPU) time consumption were not easily attainable through the Java programming language; they required new methods and classes created in the test applications. Evaluation of this product showed the rate that data can be sent across the network. Performance rates are better on Linux platforms than AIX and Sun platforms. Compared to previous C++ programming language API, the performance evaluation also shows the language differences for the implementation. The Java API of the DDS has a lower throughput performance than the C++ API.

  17. The New Mexico Tech Extrasolar Spectroscopic Survey Instrument (NESSI)

    Science.gov (United States)

    Creech-Eakman, Michelle J.; Jurgenson, C.; Vasisht, G.; Swain, M.; Boston, P.; Santoro, F.

    2010-01-01

    We present the design and scientific objectives behind NESSI, a near-infrared spectroscopic purpose-built for studying exoplanet atmospheres. This instrument is being designed and assembled by a team of scientists and engineers at New Mexico Tech (NMT), the Magdalena Ridge Observatory (MRO) and NASA's Jet Propulsion Lab (JPL), and is scheduled for deployment in late 2010 at the MRO 2.4m telescope. NESSI's unique design is driven by recent space and ground-based NIR spectroscopy of exoplanet atmospheres by members of our team. Optimization of the instrument to achieve 0.01% relative accuracies in spectra of exoplanetary molecular constituents requires careful attention to certain design features and a new technical approach. We present an overview of NESSI's design, including the four major subassemblies: 1) a field derotator, 2) a reimaging module, 3) an optical guiding module, and 4) a multi-object spectrograph subassembly. We also present an overview of our science program specifically designed to build the community of exoplanet researchers and students in NM. The financial support of our team and NESSI itself have been made possible by a NM NASA EPSCoR grant, matching funds from the NMT administration, and internal support for the NESSI hardware from Dr. Van Romero, NMT's Research Vice-President.

  18. "Sci-Tech - Couldn't be without it !"

    Science.gov (United States)

    2002-03-01

    Launch of a Major European Outreach Programme Seven of Europe's leading Research Organizations [1] launch joint outreach programme for the European Science and Technology Week at the Technopolis Museum in Brussels on 22 March. Their aim is to show Europeans how today's society couldn't be without fundamental research . Could you imagine life without mobile phones, cars, CD players, TV, refrigerators, computers, the internet and the World Wide Web, antibiotics, vitamins, anaesthetics, vaccination, heating, pampers, nylon stockings, glue, bar codes, metal detectors, contact lenses, modems, laser printers, digital cameras, gameboys, play stations...? Technology is everywhere and used by everyone in today's society, but how many Europeans suspect that without studies on the structure of the atom, lasers would not exist, and neither would CD players? Most do not realise that most things they couldn't be without have required years of fundamental research . To fill this knowledge gap, the leading Research Organizations in Europe [1], with the support of the research directorate of the European Commission, have joined forces to inform Europeans how technology couldn't be without science, and how science can no longer progress without technology. The project is called...... Sci-Tech - Couldn't be without it! Sci-Tech - Couldn't be without it! invites Europeans to vote online in a survey to identify the top ten technologies they can't live without. It will show them through a dynamic and entertaining Web space where these top technologies really come from, and it will reveal their intimate links with research. Teaching kits will be developed to explain to students how their favourite gadgets actually work, and how a career in science can contribute to inventions that future generations couldn't be without. The results of the survey will be presented as a series of quiz shows live on the Internet during the Science Week, from 4 to 10 November. Sci-tech - Couldn't be without

  19. Life Sciences at the University of Yachay Tech in Ecuador

    Directory of Open Access Journals (Sweden)

    Graciela Salum

    2016-09-01

    Full Text Available Yachay Tech University, home for more than 900 students and growing, has entered a new era and made a step forward in its development and fulfillment of the hopes placed on it. Indeed, its Schools have launched their careers offering the students a wide range of choices among programs of high academic level. The School of Biological Sciences and Engineering has started its two careers. The first one, coined "Biology," is designed for students aiming to gain knowledge either in "Organisms, Ecology and Evolution" or "Molecular and Cellular Biology." The second path, referred to as "Biomedical Engineering", is the first program of its type in Ecuador and is intended for students wishing to apply the principles and problem-solving techniques of Engineering to Biology and Medicine. These students will be able to acquire knowledge at the interface between Biology and Medicine, on one side, and Natural Sciences, such as Physics and Chemistry, and Engineering sciences, such as Flow Dynamics, Informatics and Electronics, on the other side.

  20. The RXL motif of the African cassava mosaic virus Rep protein is necessary for rereplication of yeast DNA and viral infection in plants

    Energy Technology Data Exchange (ETDEWEB)

    Hipp, Katharina; Rau, Peter; Schäfer, Benjamin [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany); Gronenborn, Bruno [Institut des Sciences du Végétal, CNRS, 91198 Gif-sur-Yvette (France); Jeske, Holger, E-mail: holger.jeske@bio.uni-stuttgart.de [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany)

    2014-08-15

    Geminiviruses, single-stranded DNA plant viruses, encode a replication-initiator protein (Rep) that is indispensable for virus replication. A potential cyclin interaction motif (RXL) in the sequence of African cassava mosaic virus Rep may be an alternative link to cell cycle controls to the known interaction with plant homologs of retinoblastoma protein (pRBR). Mutation of this motif abrogated rereplication in fission yeast induced by expression of wildtype Rep suggesting that Rep interacts via its RXL motif with one or several yeast proteins. The RXL motif is essential for viral infection of Nicotiana benthamiana plants, since mutation of this motif in infectious clones prevented any symptomatic infection. The cell-cycle link (Clink) protein of a nanovirus (faba bean necrotic yellows virus) was investigated that activates the cell cycle by binding via its LXCXE motif to pRBR. Expression of wildtype Clink and a Clink mutant deficient in pRBR-binding did not trigger rereplication in fission yeast. - Highlights: • A potential cyclin interaction motif is conserved in geminivirus Rep proteins. • In ACMV Rep, this motif (RXL) is essential for rereplication of fission yeast DNA. • Mutating RXL abrogated viral infection completely in Nicotiana benthamiana. • Expression of a nanovirus Clink protein in yeast did not induce rereplication. • Plant viruses may have evolved multiple routes to exploit host DNA synthesis.

  1. Platão e a poesia na República

    Directory of Open Access Journals (Sweden)

    Maria da Penha Villela-Petit

    2003-06-01

    Full Text Available Platão não é o iniciador, e sim o herdeiro da "velha divergência" entre filósofos e poetas. A motivação ético-teológica, que já animava Xenófanes,vai se reatualizar na República. Para poder apreciar o sentido dessa reatualização, importa que não se considere o Livro X isoladamente, mas se atente para os primeiros livros do diálogo. Neles, e com vistas a uma melhor determinação do justo -que é o que está em pauta-, Platão mostra a necessidade de se discutir as afirmações dos poetas. Trata-se assim de destituí-los da autoridade de que ainda gozam na educação e na opinião comum. Só graças à discussão filosófica e a uma educação por ela inspirada -o que pressupõe a produção ou a seleção de mitos- é que se pode esperar uma maior realização da justiça, tanto no plano do indivíduo (do governo de sua alma quanto no nível da cidade. A leitura aqui proposta das "razões" de Platão na República não impede que reconheçamos a importância da tragédia para a compreensão da existência humana, inclusive no que toca à idéia do divino.Plato is not the initiator, but rather the heir of the "old quarrel", between philosophers and poets. The ethical and theological motivation that drove Xenophanes is brought to date in the Republic. In order to realize that, one must take into account the whole of the dialogue - where the definition of justice is at stake - and, more precisely, its first books. There, Plato shows how important it is to put the poets' claims to question. The point is, after all, to deprive them of the authority they enjoy in what concerns educational matters as well as with public opinion. It is only through an education which is inspired by philosophical questioning - which also implies the production and selection of myths - that one can expect more justice both on the individual (the gouvernment of his soul and on the city levels. The reading we propose of Plato's "reasons" in the Republic does

  2. Discurso de orden.Tribunal supremo de justicia de la república Bolivariana de Venezuela

    Directory of Open Access Journals (Sweden)

    José Manuel Delgado Ocando

    2001-01-01

    Full Text Available José Manuel Delgado Ocando, nos presenta un original y brillante análisis de la realidad política venezolana. Bien es sabido que a raíz de la elección presidencial de Hugo Chávez Frías, éste convoca a un referéndum popular con la expresa intención de constituir un nuevo orden constitucional. Tal inusual experiencia de la ciudadanía en la participación de los “asuntos de Estado”, generó no pocas controversias sobre el conflicto de competencias entre la Asamblea Nacional Constituyente (poder constituyente y el Congreso de la República (poder constituido. No previsto en la Constitución de 1961 este inédito protagonismo popular y la coexistencia de dos regímenes constitucionales distintos, le toca a la Corte Suprema de Justicia legislar sobre este caso particular teniendo que apelar a la doctrina de la supraconstitucionalidad a fin de dirimir el conflicto normativo y ratificar la legalidad de la consulta referendaria que da origen a la Asamblea Nacional Constituyente. El autor se vale de una compleja hermenéutica jurídico-política para interpretar este inédito fenómeno de la filosofía política moderna que se ha vivido en Venezuela, así como para confirmar su confianza en la producción originaria del derecho cuando ésta es reclamada por la soberanía popular.

  3. "Sobre la justicia en el libro "La República" de Platón"

    Directory of Open Access Journals (Sweden)

    Walter Olivari

    2008-01-01

    Full Text Available La justicia, ha sido siempre un tema presente en la filosofía y con más notoriedad en la filosofía clásica, por ello resulta saludable, atractivo y de valor el análisis de los textos griegos al respecto. En este punto, Platón es quizás el más estudiado, siempre sus diálogos resultan útiles para quien recorre sus páginas, ya convertidas en verdaderos monumentos de la filosofía, con pasajes y afirmaciones hasta hoy irrefutables, además haciendo de su maestro Sócrates un personaje invalorable para la sabiduría universal. La innata ansia por una vida mejor, empuja al hombre casi siempre a la búsqueda de un mundo sin defectos. Esta es la razón de sus ilusiones utópicas de alcanzar justica, entendida ella como la perfecta armonía en la convivencia social. De la producción platónica, extensa, variada y valiosa, por todo lo que trata y por su sobrevivencia al paso de los años, la obra La República ocupa un lugar de preferencia, por eso estudiar sus paginas y repasar, tanto como re-pensar sus conceptos, es buen estimulo para quienes desean conocer temas de trascendencia en Filosofía, Derecho o afines. Volver a los clásicos es siempre un deber, ellos siempre son fascinantes y sus enseñanzas perduran con gran lozanía, a prueba de todo elemento corrosivo, por tanto no hay pretexto que valga, como para no estudiar, lo que sobre la justicia con genialidad nos comentaron hace ya tantos años.

  4. High burnup effects on fuel behaviour under accident conditions: the tests CABRI REP-Na

    Science.gov (United States)

    Schmitz, Franz; Papin, Joelle

    A large, performance based, knowledge and experience in the field of nuclear fuel behaviour is available for nominal operation conditions. The database is continuously completed and precursor assembly irradiations are performed for testing of new materials and innovative designs. This procedure produces data and arguments to extend licencing limits in the permanent research for economic competitiveness. A similar effort must be devoted to the establishment of a database for fuel behaviour under off-normal and accident conditions. In particular, special attention must be given to the so-called design-basis-accident (DBA) conditions. Safety criteria are formulated for these situations and must be respected without consideration of the occurrence probability and the risk associated to the accident situation. The introduction of MOX fuel into the cores of light water reactors and the steadily increasing goal burnup of the fuel call for research work, both experimental and analytical, in the field of fuel response to DBA conditions. In 1992, a significant programme step, CABRI REP-Na, has been launched by the French Nuclear Safety and Protection Institute (IPSN) in the field of the reactivity initiated accident (RIA). After performing the nine experiments of the initial test matrix it can be concluded that important new findings have been evidenced. High burnup clad corrosion and the associated degradation of the mechanical properties of the ZIRCALOY4 clad is one of the key phenomena of the fuel behaviour under accident conditions. Equally important is the evidence that transient, dynamic fission gas effects resulting from the close to adiabatic heating introduces a new explosive loading mechanism which may lead to clad rupture under RIA conditions, especially in the case of heterogeneous MOX fuel.

  5. Apparent Level of Sci-tech Achievements and Sci-tech Evaluation%科技成果的表观水平与科技评价

    Institute of Scientific and Technical Information of China (English)

    禹慧明

    2012-01-01

    This paper gives the concept of " apparent level of sci - tech achievements ". It discusses the reasons that the apparent level is popular in the sci -tech evaluation, the drawbacks that the apparent level is used for sci - tech evaluation , and the countermeasures to improve the quality of sci - tech achievements . The paper also points out that sci - lech evaluation will identify the gaps which has a "potential energy " i. e. "energy of position". The sci - tech rewards is the external conditions of transforming " potential energy " into the " kinetic energy ". Corrects evaluation can lead to correct identification, proper to reward and correct guidance. The reform should be necessary to take sci - lech evaluation and incentives as the main line , the various system innovation should be around the main line.%提出了“科技成果表观水平”的概念.论述了表观水平流行于科技成果评价的原因,运用表观水平进行科技评价存在的弊端以及提高科技成果质量的对策.指出科技评价可以发现差距,有差距就会产生“势能”,科技奖励是将“势能”转化成“动能”和动力的外在条件;只有正确评价才能正确鉴别,才能奖罚得当,才能正确引导;制度改革应以科技评价和激励政策为主线,从上到下的各种制度都应围绕这条主线进行创新.

  6. 78 FR 52430 - Withdrawal of Approval of New Animal Drug Applications; Quali-Tech Products, Inc.; Bambermycins...

    Science.gov (United States)

    2013-08-23

    ... Animal Drug Applications; Quali- Tech Products, Inc.; Bambermycins; Pyrantel; Tylosin; Virginiamycin... (pyrantel tartrate), NADA 132-705 for FLAVOMYCIN (bambermycins), and NADA 133-335 for STAFAC...

  7. Empirical Study on the Measurement of the Technical Efficiency of Jilin Province’s Five High-tech Industries

    Directory of Open Access Journals (Sweden)

    Yao Jie

    2017-01-01

    Full Text Available This paper first analyzed the industrial distribution of Jilin province’s high-tech enterprises, and then selected 13 input and output indicators based on analyzing the influence factors of high-tech industry. Through the correlation analysis between each indicator’s relevant data, the paper constructed the technical efficiency evaluation model of Jilin Province’s high-tech industries including 12 indicators. After that it measured the technical efficiency of Jilin Province’s five high-tech industries from 2004 to 2013 by using DEA analysis method. Finally, this paper drew conclusions and gave suggestions.

  8. 7th FTRA International Conference on Future Information Technology (FutureTech 2012)

    CERN Document Server

    Leung, Victor; Wang, Cho-Li; Shon, Taeshik; Advances in Complex Data Modeling and Computational Methods in Statistics

    2012-01-01

    This book is about Future Information Technology, Application, and Service (FutureTech 2012 volume 2). The topics of FutureTech 2012 cover the current hot topics satisfying the world-wide ever-changing needs. The FutureTech 2012 is intended to foster the dissemination of state-of-the-art research in all future IT areas, including their models, services, and novel applications associated with their utilization. The FutureTech 2012 will provide an opportunity for academic and industry professionals to discuss the latest issues and progress in this area. In addition, the conference will publish high quality papers which are closely related to the various theories, modeling, and practical applications in many types of future technology. The main scope of FutureTech 2012 is as follows. Hybrid Information Technology Cloud and Cluster Computing Ubiquitous Networks and Wireless Communications Multimedia Convergence Intelligent and Pervasive Applications Security and Trust Computing IT Management and Service Bioinfo...

  9. A new model on the use of ubiquitous technology (U-Tech as a learning tool

    Directory of Open Access Journals (Sweden)

    Muliati Sedek

    2014-08-01

    Full Text Available Laptops, smartphones and tablets which also known as ubiquitous technology or u-tech have been widely used by students in the university. However, study on the factors influencing it usage as not many comprehensive studies have been done related to it. A review of related literature reveals that factors, namely the Technology Competency (TC, Performance Expectancy (PE, Effort Expectancy (EE, Behavioural Intention (BI, Facilitating Conditions (FC and Social Status (SS influence its usage. Thus, the focus of this study was to confirm whether the determined factors contribute towards u-tech usage among students in the institutions of higher learning, particularly in Malaysia. This study was based on a quantitative research in which the Structural Equation Modelling using AMOS was employed. The results attained from the analysis produced a reliable model towards u-tech usage. Therefore, it can be concluded that, u-tech usage described by the five factors. This study has suggested that the university administration should play an active role in disseminating any news that is related to the usefulness of u-tech.

  10. Hacia una república conservadora : el programa político del Partido Agrario Español

    Directory of Open Access Journals (Sweden)

    Luis Teófilo Gil Cuadrado

    2005-01-01

    Full Text Available El Partido Agrario Español (PAE, fundado en enero de 1934 y presidido por José Martínez de Velasco, representó, dentro de la II República española, una alternativa conservadora y, al tiempo, leal al régimen. El programa político del PAE aceptaba la República —a diferencia de otros partidos derechistas del momento, como la CEDA y los monárquicos— y defendía la unidad nacional, el establecimiento de una segunda Cámara legislativa, la protección de la agricultura y la industria mediante aranceles, el libre comercio dentro de las fronteras nacionales y la revisión de algunas leyes del primer bienio como la Reforma Agraria de 1932. El objetivo era la configuración de una República conservadora distinta, en aspectos fundamentales, a la diseñada por la Constitución de 1931 y la legislación del bienio social-republicano.The Spanish Agrarian Party (Partido Agrario Español, PAE, founded in january of 1934 and presided by José Martínez de Velasco, was, in the political life of the Spanish Second Republic, a conservative and republican option. The agrarian program accepted the republican regime —in opposition to other conservative parties, like the CEDA or the monarchists— and defended the national union, the establishment of a Senate, the protection of the national agriculture and industry trough tariffs, the free trade in the Spanish market and the revision of some laws voted in the first biennium like the Agrarian Reform, promulgated in 1932. The idea was to establish a conservative Republic, different, in some fundamental aspects, of the regime designed by the Constitution of 1931 and the legislation approved during the socialist-republican biennium.

  11. Proyectos de parcelas con servicios desarrollados por el INVI en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Pou Howley, Carlos

    1984-07-01

    Full Text Available Santo Domingo, the capital of the Dominican Republic, has not escaped the phenomenon of urban growth and the concentration of large slum areas or hovels, mainly due to the migratory movements of the peasants who have been driven from the country. As a viable solution to the enormous problem of housing in this city, INVI, with the participation of the World Bank, is putting forward projects for lots supplied with services in which infrastructure services are installed on urban land and plots or parcels of land are given to families so that they can build or complete their houses. These projects are located in places registering a greater tendency towards development. The urban plan formulated in both projects is of an eminently pedestrian nature with a reduced thoroughfare for vehicles. In the pedestrian precinct, it was possible to lay down what have been called mini-parks, which involve widening the pedestrian thoroughfare and, in addition to constituting green areas distributed throughout the projects, they also reinforce the idea of a neighbourhood. Because of the scope of the projects, a series of installations have been provided to maintain their own community services, as well as commercial and institutional ones, which are distributed strategically.Santo Domingo, capital de la República Dominicana, no ha escapado al fenómeno del crecimiento urbano y a la concentración de grandes tugurios o arrabales, debido principalmente a los movimientos migratorios de los campesinos expulsados del campo. Como una solución viable al gran problema de la vivienda de esta ciudad, el INVI, con la participación del Banco Mundial, plantea proyectos de parcelas con Servicios en los cuales se instalan servicios de infraestructura en tierras urbanas y se proporcionan parcelas o solares a familias para que éstas construyan o completen sus viviendas. Se ubican estos proyectos en sitios que acusan una mayor tendencia de desarrollo. El esquema urbano

  12. A natureza dos números na República de Platão

    Directory of Open Access Journals (Sweden)

    Anastácio Borges de Araújo Jr.

    2010-12-01

    Full Text Available É incontestável a presença das matemáticas nos diálogos de Platão, todavia o alcance e o sentido desta presença é matéria de controvérsia entre os especialistas. Alguns acreditam que os temas matemáticos empregados nos diálogos são fantasias matemáticas, outros defendem baseados, sobretudo no testemunho de Aristóteles, que Platão teria substituído na sua hipótese as formas inteligíveis pelos números ideais. Sem tomar partido de antemão nestas querelas, o que propomos aqui é uma investigação acerca da natureza dos números fundamentada exclusivamente nos textos de Platão, particularmente orientada por uma passagem do livro VII do diálogo República(525 b11- c3, em que Sócrates diz o seguinte: "Seria, portanto, conveniente colocar este estudo, ò Glaucon, dentro de uma legislação e persuadir aqueles que vão participar das grandes coisas na cidade a irem ao cálculo e a aplicarem-se a ele, não nos seus afazeres privados, mas até chegarem à contemplação da natureza dos números através da própria intelecção (...".The presence of the mathematics in Plato's dialogues is unquestionable. However, its reach and sense is controversial for some specialists. Some believe that the mathematical themes employed in the dialogues are mathematical fantasies; on the other hand, others defend, based on the Aristotle's testimonies, that Plato would have substituted the intelligible forms by the ideal numbers in his hypothesis. Having not taken part in the quarrel, we propose an investigation on the nature of the numbers based exclusively in Plato's texts, particularly oriented by the a passage in book VII of Republic (525 b11 - c3, in which Socrates says: "Then it would be fitting, Glaucon, to set this study down in law and persuade those who are going to participate in the greatest things in the city to go to calculation and to take it up, not after the fashion of private men, but stay with it until they come to the

  13. Galeguismo, agro e agrarismo na Galicia da II República

    Directory of Open Access Journals (Sweden)

    Cabo Villaverde, Miguel

    2009-12-01

    Full Text Available The Partido Galeguista (PG was created in December 1931 as the expression of Galician nationalism during the Second Republic (1931-1936. Prior to that, the Galician nationalists had been very influential in the cultural sphere but rather powerless from a political point of view. The PG regarded agriculture and peasantry as a priority, not only because of their objective importance in the Galician economy and society in the 1930s but also because they were seen as the bulwarks of the national identity. In fact, the characteristics, needs and paths of development of the Galician agrarian sector were usually defined as opposed to those of the rest of Spain. It is then understable that the PG tried to win the agrarian unions over, and that it is arguable that it had plenty of common features with the so-called Agrarian Parties in other European regions.

    O Partido Galeguista (PG foi creado en decembro de 1931 como expresión do nacionalismo galego durante a Segunda República (1931-1936. Con anterioridade, os nacionalistas galegos foron moi influíntes no eido cultural pero maiormente inoperantes dende o punto de vista político. O PG consideraba a agricultura e o campesiñado como unha prioridade, non só pola súa importancia obxectiva na economía e sociedade galegas dos anos trinta senón tamén porque eran vistos como os baluartes da identidade nacional. De feito, as características, necesidades e vías de desenvolvemento do sector agrario galego eran normalmente definidas en oposición ás do resto de España. É daquela comprensible que o PG tentase gañarse ás sociedades agrarias, e mesmo se pode afirmar que tiña moitos puntos en común cos chamados Partidos Agrarios doutras rexións europeas.

  14. Virtud en La República de Platón y El Príncipe de Maquiavelo

    OpenAIRE

    2014-01-01

    Desde el punto de vista de la ética de virtudes, el presente ensayo compara los filósofos-reyes de Platón con el príncipe de Maquiavelo. Primeramente, se define la ética de virtudes; seguidamente, se explica la manera en que se manifiesta la virtud en La República de Platón y El Príncipe de Maquiavelo. Finalmente, se valoran las semejanzas y diferencias entre ambos autores con respecto al concepto de virtud.

  15. Proteinopatías amiloides: desarrollo de un nuevo sistema modelo en microorganismos basado en RepA-WH1

    OpenAIRE

    Gasset Rosa, Fátima

    2012-01-01

    Las bases moleculares de la agregación de las proteínas amiloides son similares en todos los organismos, sean provenientes de microorganismos procariotas, hongos o metazoos. Muchas de estas proteínas poseen naturaleza priónica y son agentes causantes de enfermedades fatales (neurodegenerativas o sistémicas), cuyos mecanismos quedan todavía por esclarecer como previo paso hacia posibles terapias. Considerando estos presupuestos, el estudio de la amiloidosis de RepA-WH1, una proteína iniciadora...

  16. O surgimento da escola médica paulista no contexto brasileiro da Primeira República (1891 a 1930

    Directory of Open Access Journals (Sweden)

    Márcia Regina Silva Barros da

    2004-01-01

    Full Text Available Este trabajo intenta compreender el proceso de instauración de la enseñanza médica en São Paulo, Brasil, entre finales del siglo XIX y principios del siglo XX. Para tanto se discute los cambios que ocurrieron en el Estado de São Paulo en los comienzos del periodo de la República, en el contexto de la creación de nuevas instituciones médicas, tales como la Sociedade de Medicina e Cirurgia y el Serviço Sanitário, asi como surgimiento de varias revistas de la area.

  17. Experiencias de colaboradores tuneros en la República Democrática de Timor-Leste

    Directory of Open Access Journals (Sweden)

    Juana Magdalena Castro García

    2014-08-01

    Full Text Available En la presente comunicación breve se relatan las experiencias de una enfermera que se desempeñó profesionalmente en la asistencia médica y la docencia en la República Democrática de Timor Leste. A través de las vivencias compartidas se ponen de manifiesto los valores humanos que caracterizan al personal de la salud cubana, entre ellos: el humanismo, la responsabilidad, la laboriosidad y la solidaridad, características que muestran un ejemplo del papel de la mujer cubana en la Revolución

  18. Variedades de vegetales y de hongos existentes en la República Argentina y poseedoras de principios psicoactivos /

    OpenAIRE

    Acosta, Carlos Alberto

    2009-01-01

    Tesis [Maestría] -- Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Salud Pública En este trabajo se ha recopilado información correspondiente a 25 géneros, 34 especies de vegetales y 4 géneros ,4 especies de hongos que pueden ser encontrados en el espacio territorial de la República Argentina. Todos estos organismos poseen principios psicoactivos. Haciéndose referencia a la forma que se utilizan como fuente alternativa de sustancias psicoactivas y/o a su potencia...

  19. Acoso laboral: ¿Cómo intervenir? : Una mirada desde la Universidad de la República del Uruguay

    OpenAIRE

    Menéndez, Manuel; Cánepa, Elisa

    2014-01-01

    En el año 2010 la Universidad de la República del Uruguay, la principal universidad del país, que es pública y cogobernada, creó un Programa de Salud Mental (PSM) para abordar las problemáticas de salud mental de sus estudiantes y trabajadores. El PSM decidió abordar la problemática del acoso laboral debido a la gran demanda existente. Una investigación estadística realizada por el PSM sobre la Calidad de Vida de los trabajadores docentes y no docentes de la Universidad, publicada en el añ...

  20. Alguns ectoparasitas e protozoários em bovinos da República da Guiné-Bissau

    OpenAIRE

    ROSA, FERNANDA; Crespo, Maria Virgínia; Travassos Dias, J. A.

    1998-01-01

    Os autores assinalam a presença de algumas espécies de ixodídeos (Amblyomma variegatum, Boophilus annulatus, B. geigy e Hyalomma sp.) localizados em diferentes regiões do corpo de bovinos autóctones da República da Guiné-Bissau, colhidos entre Novembro de 1990 e Março de 1991. A pesquisa de protozoários, efectuada principalmente em esfregaços de sangue revelou a presença de Anaplasma marginale, Theileria mutans, Babesia bigemina e Sarcocystis sp. Não foram encontradas lesões relacionada...

  1. El matrimonio como estrategia en la carrera política durante el último tramo de la República

    OpenAIRE

    Castán, Santiago

    2011-01-01

    En el último siglo de la República el matrimonio se convirtió en un poderoso instrumento para alcanzar el poder político o mantenerse entre la élite gobernante. Además de la importancia del matrimonio desde un punto de vista socio-político más que jurídico, el estudio se centra en las alianzas político-familiares celebradas por personajes claves de este período como César, Pompeyo, Cicerón y Marco Antonio

  2. L’ethnographie et l’anthropologie religieuses de Cuba : repères historiques et bibliographiques

    OpenAIRE

    2013-01-01

    Le développement que connaissent aujourd’hui les études sur Cuba, en particulier l’ethnographie des pratiques religieuses dites « d’origine africaine », n’est pas le fruit du hasard. Cet article introductif revient sur les conditions sociohistoriques spécifiques qui ont présidé à ce renouveau en les replaçant dans le contexte politique et idéologique cubain. Afin d’établir quelques repères bibliographiques dans un domaine d’études devenu particulièrement dynamique, il évoque aussi certaines t...

  3. Rep-PCR typing of Staphylococcus spp. strains in meat paste production line and identification of their origin

    Directory of Open Access Journals (Sweden)

    Ivan Manga

    2015-05-01

    Full Text Available A meat paste production line and its microbial parameters have been evaluated in single Czech company. The raw meat paste samples before heat treatment were tested positively for the presence of three staphylococci species: Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus epidermidis. Subsequent microbial analysis of meat paste components and ingredients (fresh meat, water, spices, equipment identified only the spices used as positive for S. aureus (coriander, cinnamon, badian, mustard – (10 - 40 cfu/g and S. haemolyticus strains (juniper, ginger. The collection of sixteen collected strains (S. aureus (n = 4, S. haemolyticus (n = 4, S. epidermidis (n = 8 has been typed with the rep-PCR method utilising (GTG5 primer. Analysis of the fingerprints using the unweighted pair-group method using arithmetic averages (UPGMA clustering method revealed presence of eleven strain clusters with similarity lower than 90%: two fingerprint clusters of S. aureus, three individual clusters characteristic for S. haemolyticus and six different S. epidermidis specific clusters. The S. aureus strains from different types of spice were identical, resp. very similar. Molecular tracking composed from the rep-PCR analysis of acquired isolates and comparison among all collected fingerprints confirmed the spices to be the source of both S. aureus and S. haemolyticus strains identified in raw meat paste. The additional rep-PCR analysis of the S. epidermidis collection confirmed usability and performance of this method. The antibiotic susceptibility to fourteen individual antibiotics has been examined among the collected staphylococci strains. The predominant erythromycin resistance (68.8% was followed with the resistance to amoxicillin/clavulanic acid (56.2%. Other resistances observed were less frequent (clindamycin – 12.5%, oxacillin – 6.3%, tetracycline – 6.3%, sulphamethoxazole-trimethoprim – 6.3%, chloramphenicol – 6.3%, novobiocin – 6

  4. Virtud en La República de Platón y El Príncipe de Maquiavelo

    Directory of Open Access Journals (Sweden)

    Katherine Masís Iverson

    2014-11-01

    Full Text Available Desde el punto de vista de la ética de virtudes, el presente ensayo compara los filósofos-reyes de Platón con el príncipe de Maquiavelo. Primeramente, se define la ética de virtudes; seguidamente, se explica la manera en que se manifiesta la virtud en La República de Platón y El Príncipe de Maquiavelo. Finalmente, se valoran las semejanzas y diferencias entre ambos autores con respecto al concepto de virtud.

  5. Yield oil of Jatropha curcas seeds of trees irrigated and fertilized with OMM-Tech; Rendimento de oleo de sementes de pinhao manso submetido a irrigacao e adubacao com OMM-Tech

    Energy Technology Data Exchange (ETDEWEB)

    Evangelista, Adao W.P.; Alves Junior, Jose; Barbosa, Ricardo A.F.; Frazao, Joaquim J.; Araujo, Fausto J.M. [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Escola de Agronomia e Engenharia de Alimentos. Setor de Engenharia Rural], E-mail: awpego@bol.com.br

    2010-07-01

    The purpose of this study was to evaluate the effects of irrigation and application of Organo-Minerals-Marine + Biotech (OMM-Tech) in yield oil of Jatropha curcas seeds. The experiment was conducted in an experimental area located in Federal University of Lavras, Brazil. A randomized block experimental design with subdivided parcels and three replications was used. The parcels were submitted to different OMM-Tech fertilizer application methods: T1 = control (no OMM-Tech); T2 = soil application (120 kg ha{sup -1} of OMM-Tech in a powder form); T3 = leaf application (OMM-Tech in a liquid form with a 5% concentration); T4 = soil + leaf application (60 kg ha{sup -1} of OMM-Tech in powder form + OMM-Tech in liquid form with a 2.5% concentration). The sub-plots received two different water management treatments: irrigated and no irrigated. A drip irrigation system with drippers spaced by 0.50 m was used. We evaluated yield oil of seeds in first production year. Jatropha trees irrigated showed a higher seeds oil yield than no irrigated trees. However, fertilization with OMM-Tech no influenced seed oil yield. Seeds oil yield of Jatropha trees irrigated was 34%, and no irrigated 27%. (author)

  6. How To Implement a Tech Prep Program Based on the Rhode Island Model. Tech Prep Associate Degree Program. Technical Programs. Business/Office Administration Programs. Allied Health/Dental Health Programs.

    Science.gov (United States)

    Community Coll. of Rhode Island, Warwick.

    This implementation guide contains information based on experiences that occurred during the development and implementation of the Rhode Island Tech Prep Model. It is intended to assist educators in addressing challenges and obstacles faced by the program early in the planning process. It begins with a rationale for tech prep. Rhode Island…

  7. Varying Interpretations of Technology as a Problem in Markets for Customised High-Tech Products

    DEFF Research Database (Denmark)

    Vendelø, Morten Thanning; Constantiou, Ioanna

    2012-01-01

    Firms involved in contracting and implementation of customised high-tech products face a number of challenges in their relationships with customers because of the underlying variability of complex technologies. Existing research proposes the use of rational decision models and represents technology...... as an input to the firm's production function that generates a specific return on investment when used appropriately. As such, existing research does not account for the parties' varying interpretations of complex technology. If these interpretations are not revealed and resolved they may decrease customer......-tech product in the software industry is analysed. Based on the insights obtained, we discuss the potential use of inquiring dialogue as a means to reveal information about the different interpretations held by the parties involved in contracting and implementing a customised high-tech product....

  8. Collaborative Innovation Research on High-tech Industry in the Center Delta

    Directory of Open Access Journals (Sweden)

    Yan Jingdong

    2017-01-01

    Full Text Available As a strong point in the Middle Rises Strategy, the Center Delta is of great significance to high-tech industry development. While the collaborative innovation is an effective way to promote the coordinated development of regional economy. This article selected electronic and communication equipment manufacturing industry of 3 provinces in the Center Delta as samples, built evaluation index system of collaborative innovation of high-tech industry, and put the relevant data into the system coordination degree model, in order to get the synergy of industrial innovation system and innovation environment system of 3 provinces. The empirical results shown that the industrial innovation system and innovation environment system coordination degree of Hubei province was the highest, while Jiangxi province was the lowest. Based on the empirical result analysis of the above-mentioned systems, this article put forward suggestions to promote the development of the high-tech industry collaborative innovation in the Center Delta.

  9. Elemento material de los decretos con fuerza de ley propiamente dichos en la Constitución de la República Bolivariana de Venezuela de 1999

    Directory of Open Access Journals (Sweden)

    Fabiola del del Valle Duarte

    2008-01-01

    Full Text Available El objetivo general de esta investigación consiste en determinar el elemento material de los decretos con fuerza de ley propiamente dichos en la Constitución de la República Bolivariana de Venezuela de 1999. Se utiliza la estrategia de investigación documental, sustentada en el método analítico. Las fuentes para la recolección de información atienden a cuatro ámbitos: constitucional, legal, doctrinal y jurisprudencial. Los decretos con fuerza de ley propiamente dichos, contemplados en la Constitución de la República Bolivariana de Venezuela de 1999, constituyen actos jurídicos normativos de efectos generales, con rango legal, dictados por el Presidente de la República en Consejo de Ministros, cuyo elemento material comprende dos concurrentes subelementos: ausencia de límites materiales expresos en la Constitución de la República Bolivariana de Venezuela de 1999 y sometido a directrices, propósitos y marco en materias de competencia nacional establecidos en la ley habilitante. La Constitución de la República Bolivariana de Venezuela de 1999 permite inferir la presencia de límites materiales implícitos. Cada ley habilitante, sancionada por la Asamblea Nacional, configura el único límite material expreso de los decretos con fuerza de ley propiamente dichos por ella autorizados.

  10. Experimental particle physics research at Texas Tech University

    Energy Technology Data Exchange (ETDEWEB)

    Akchurin, Nural [Texas Tech Univ., Lubbock, TX (United States); Lee, Sung-Won [Texas Tech Univ., Lubbock, TX (United States); Volobouev, Igor [Texas Tech Univ., Lubbock, TX (United States); Wigmans, Richard [Texas Tech Univ., Lubbock, TX (United States)

    2016-06-22

    The high energy physics group at Texas Tech University (TTU) concentrates its research efforts on the Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) and on generic detector R&D for future applications. Our research programs have been continuously supported by the US Department of Energy for over two decades, and this final report summarizes our achievements during the last grant period from May 1, 2012 to March 31, 2016. After having completed the Run 1 data analyses from the CMS detector, including the discovery of the Higgs boson in July 2012, we concentrated on commissioning the CMS hadron calorimeter (HCAL) for Run 2, performing analyses of Run 2 data, and making initial studies and plans for the second phase of upgrades in CMS. Our research has primarily focused on searches for Beyond Standard Model (BSM) physics via dijets, monophotons, and monojets. We also made significant contributions to the analyses of the semileptonic Higgs decays and Standard Model (SM) measurements in Run 1. Our work on the operations of the CMS detector, especially the performance monitoring of the HCAL in Run 1, was indispensable to the experiment. Our team members, holding leadership positions in HCAL, have played key roles in the R&D, construction, and commissioning of these detectors in the last decade. We also maintained an active program in jet studies that builds on our expertise in calorimetry and algorithm development. In Run 2, we extended some of our analyses at 8 TeV to 13 TeV, and we also started to investigate new territory, e.g., dark matter searches with unexplored signatures. The objective of dual-readout calorimetry R&D was intended to explore (and, if possible, eliminate) the obstacles that prevent calorimetric detection of hadrons and jets with a comparable level of precision as we have grown accustomed to for electrons and photons. The initial prototype detector was successfully tested at the SPS/CERN in 2003-2004 and evolved over the

  11. 14th High-Tech Plasma Processes Conference (HTPP 14)

    Science.gov (United States)

    2017-04-01

    Preface The High-Tech Plasma Processes Conference (HTPP) is a bi-annual international conference based in Europe with topics encompassing the whole area of plasma processing science. This conference is open to all the international community in the world involved in plasma science and plasma technology. The aim of the conference is to bring different scientific communities together, facilitate the contacts between science, technology and industry and provide a platform for the exploration of both fundamental topics and new applications of plasmas. For this edition of HTPP, as was the case for the last, we have achieved a well balanced participation from the communities of both thermal and non-thermal plasma researchers. 75 people from 17 countries attended the conference with the total number of contributions being 74, consisting of 19 invited talks and 55 poster contributions. As a HTPP tradition a poster competition has been carried out during the conference. The winner of the poster competition was Fabrice Mavier from Université de Limoges, France with his paper “Pulsed arc plasma jet synchronized with drop-on-demand dispenser” All the participants also ejoyed the social program including an “unconventional” tour of the city, the visit to the famous Hofbräuhaus and the dinner at the Blutenburg, a beautiful inner-city castle. We have received papers corresponding to the contributions of HTPP-2014 that have been submitted for publication in this volume of Journal of Physics: Conference Series. Each submitted contribution has been peer reviewed and the Editors are very grateful to the referees for their careful support in improving the original manuscripts. In total, 18 manuscripts have been accepted for publication covering a range of topics of plasma processing science from plasma fundamentals to process applications through to experiments, diagnostics and modelling. We deeply thank the authors for their enthusiastic and high-grade contributions and we

  12. rep-PCR指纹图谱技术在乳酸菌鉴定中的应用%Application of Rep-PCR technique for the identification of lactic acid bacteria

    Institute of Scientific and Technical Information of China (English)

    满朝新; 迟涛; 胡博韬; 房玉国; 王旻; 周艳秋; 韩琳琳; 胡惠秩; 姜毓君

    2010-01-01

    采用了 rep-PCR指纹图谱技术,对分离自内蒙古通辽地区的传统发酵乳中的乳酸菌进行了鉴定和多样性分析.应用rep-PCR指纹图谱技术能够对实验菌株达到非常好的分辨能力.结果表明,该地区的乳酸菌呈现出非常高的多样性,其中Lactobcillus plantarum和Lactobacillus helveticus等6种菌种是这些传统发酵乳中常见的种,而植物乳杆菌Lactobacillus plantarum为优势种;而且还发现同一乳酸菌种群指纹图谱存在一些特征性的条带,这将为我们快速鉴定乳酸菌提供了理论依据.

  13. Iowa High School High Tech: Promoting Careers in Technology for Students with Disabilities. Final Report and Implementation Manual.

    Science.gov (United States)

    McQuillen, Terry; Nietupski, John; Berg, Deana Duncan; Daugherty, Vicki; Bildstein, Stephanie

    This final report and implementation manual describes the activities and outcomes of Iowa's High School High Tech (HSHT) program, a joint effort of Grant Wood Area Education Agency and Goodwill Industries of Southeast Iowa to inspire students with disabilities to pursue high tech careers. The program provides opportunities for students to learn…

  14. 77 FR 5291 - Thermo Tech Technologies Inc., T.V.G. Technologies Ltd., and Visual Frontier, Inc.; Order of...

    Science.gov (United States)

    2012-02-02

    ... From the Federal Register Online via the Government Publishing Office ] SECURITIES AND EXCHANGE COMMISSION Thermo Tech Technologies Inc., T.V.G. Technologies Ltd., and Visual Frontier, Inc.; Order of... lack of current and accurate information concerning the securities of Thermo Tech Technologies...

  15. E-mail service provided by Virginia Tech's server (pop.vt.edu, imap.vt.edu) is offline

    OpenAIRE

    Hincker, Lawrence

    2007-01-01

    E-mail service provided by Virginia Tech's server (pop.vt.edu or imap.vt.edu) is offline. The server has experienced a failure for two of its three power supplies. The maintenance contractor expects to have the repair components at Virginia Tech by midday Monday, March 5, 2007.

  16. Engineering for problem solving in future: Eco-social market economy and eco-social tech

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The paper differentiates approaches in technology (end-of-pipe, cleaner production, industrial ecology, zero emission and eco-social tech) and compares them in respect to the problem solving capacity on the ecological as well as social dimension by showing the eco-impact reduction and job creation. Eco-social-tech represents the approach with highest problem solution as it is based on “eco-social market economy”, which will the replace free market economy. The deep background of these innovations is “ecosophy”, the wisdom of nature, which serves as guideline for eco-restructuring the world.

  17. Raising Generation Tech Preparing Your Children for a Media-Fueled World

    CERN Document Server

    Taylor, Jim

    2012-01-01

    Today's children are being raised as 'digital natives' in a world dominated by popular culture and technology. TV shows, computers, video games, social networking sites, advertisements, and cell phones too often have an unnecessarily strong-and negative? influence on children.  But pulling the plug just isn't an option in a world where being connected is essential for success. In Raising Generation Tech,  noted parenting and new-media expert Dr. Jim Taylor explores how popular culture and technology shape children's lives. The essential message from Raising Generation Tech is that excessive

  18. Knowledge spillover and high-tech industry cluster: A literature review

    Science.gov (United States)

    Qian, Shen

    2017-04-01

    Knowledge spillover is one of the incentive forces for companies using more expenditure on R&D to shape cluster. This paper summarizes and reviews academic research literature from three aspects, of which contain the connotation of knowledge spillover in high-tech industry cluster, conduction mode of knowledge spillover effect in high-tech industry and explain factors of knowledge spillover effect. This paper devotes by assembling anterior divergent tributaries of works to assist in illuminating on this prosperous research area, based on previous research, and finally it notes that future research needs to pay attention to several aspects.

  19. Co-alignment between Environment Risk, Capital Structure, Growth and High-tech Firm Performance

    Institute of Scientific and Technical Information of China (English)

    LI Yan-xi; BAO Shi-ze

    2007-01-01

    To examine whether there is a co-alignment relationship between environment risk, capital structure, growth and high-tech firm performance, the environment risk was measured from the viewpoint of environment change, the long-term debt ratio was adopted as the measure of the capital structure, and the total asset growth and sales growth were chosen to measure the growth of high-tech firms. Regression analysis shows that there is a significant relationship between environment risk, growth and performance of hightech firms measured by the return on equity and cash flow, respectively.

  20. Current Situations of Agricultural Sci-tech Innovation and Development Path in Nantong

    Institute of Scientific and Technical Information of China (English)

    YUAN Chun-xin; SUN Qing-shan; QIU Hai-rong; ZHU Hai-yan; TANG Ming-xia; XUE Chen-xia

    2012-01-01

    Nantong is a typical region of large population and little land.The conflict between resources and environment is growing.Thus,the improvement of independent innovation ability based on current situations,oriented towards the future and relying on scientific and technological force directly decides the effect of strong economic city construction.Through analysis on achievements of agricultural sci-tech innovation works,existing problems and demand for developing modern agriculture in Nantong,we present development ideas,target orientation and basic principles of agricultural sci-tech innovation works in Nantong,and put forward eight paths.

  1. Shaking Up Biotech/Pharma: Can Cues Be Taken from the Tech Industry?

    Science.gov (United States)

    Wang, C Katherine

    2017-06-01

    The biotech and pharma (biotech/pharma) industry is in dire need of finding ways to increase efficacy, efficiency, and affordability of its products. The information and technology industry ("tech") industry, which is an industry similarly founded on inventions and innovation, may provide some food for thought. This perspective will demonstrate the shift that biotech/pharma is already making and will propose that the industry has an opportunity to compel change by adopting some aspects of the tech industry with regards to models for technology/product development and leadership attributes.

  2. CNPC to Implement Eight Sci-tech Projects for Promoting Onshore Petroleum Industry

    Institute of Scientific and Technical Information of China (English)

    Zhou Yongkang

    1996-01-01

    @@ During the Ninth Five-year Plan (1996-2000),petroleum sci-tech progress should meet the requirements of national economic growth and establishment of socialist market economic system. That means we should focus on economic efficiency to accelerate the development of onshore oil industry, implement actively the strategies of science and technologies to spur oil production, take key problems in petroleum production and construction as the major targets of sci-tech research, and push ahead with transformation of techniques into productive forces.

  3. Enterotoxigenic Bacillus spp. DNA fingerprint revealed in naturally contaminated nonfat dry milk powder using rep-PCR.

    Science.gov (United States)

    Cooper, Robin M; McKillip, John L

    2006-01-01

    Dry milk powders and functional ingredients frequently contain high levels of viable bacterial spores, some of which may result in growth of toxigenic Bacillus spp. in reconstituted and temperature-abused foods. Samples from nonfat dry milk (NFDM), infant milk formula (IMF), coffee creamer, lecithin, and cocoa powder were subjected to a short heat treatment followed by enrichment in tryptone phosphate glucose yeast extract (TPGY) broth at 32 degrees C for 12-25 hours to obtain cell densities of 10(6) CFU ml(-1). DNA was extracted using a modification of established protocol, leading to the development of an optimized method for each food system. Purified DNA was amplified by rep-PCR using extragenic sequence-targeting primers and optimized for each food. PCR fingerprints from each food were analyzed electrophoretically for banding patterns earlier correlated to that of enterotoxigenic Bacillus spp. and Bacillus cereus positive control DNA fingerprints. Reverse passive latex agglutination (RPLA) and Bacillus Diarrhoeal Enterotoxin Enzyme Linked Immunosorbent Assay (Tecra Diagnostics) confirmed the presence of HBL and NHE enterotoxin production in NFDM, Coffee creamer, infant milk formula, and two lecithin samples but not in cocoa powder. These results demonstrate the utility of rep-PCR not only as a tool for bacterial genotyping, but a unique means of quality control and hygiene monitoring in food microbiology.

  4. Repérage d’Images Ordinaires : Analyse des Requêtes des Chercheurs d’Images

    Directory of Open Access Journals (Sweden)

    Elaine Ménard

    2009-06-01

    also emphasizes the pressing necessity to optimize the methods used for image processing, in order to facilitate image retrieval and dissemination in multilingual environments. Résumé Depuis quelques années, le web est devenu un média incontournable pour la diffusion de ressources multilingues. Cependant, les différences linguistiques constituent souvent un obstacle majeur aux échanges de documents scientifiques, culturels, pédagogiques et commerciaux. En plus de cette diversité linguistique, on constate le développement croissant de bases de données et de collections composées de différents types de documents textuels ou multimédias, ce qui complexifie également le processus de repérage documentaire. Par exemple, les collections d’images numériques sont aussi nombreuses que diversifiées. Le besoin de repérer une image spécifique dans diverses collections est devenu une préoccupation partagée par plusieurs communautés. La croissance du web a mis en relief le besoin pressant de se doter d’outils propres à la description des images dans le but de faciliter leur repérage, puisque l’on retrouve celles-ci dans la plupart des ressources disponibles. Cette recherche compare le repérage d’images dans deux contextes linguistiques différents : un contexte monolingue, c’est-à-dire que la langue de la requête (français est la même que la langue d’indexation (français; et un contexte multilingue où la langue de la requête (français est différente de la langue d’indexation (anglais. Cet article présente les résultats de l’analyse des requêtes formulées par les participants pour repérer un ensemble d’images ordinaires représentant des objets de la vie quotidienne, en contexte de repérage multilingue. L’examen des termes contenus dans les requêtes des chercheurs d’images révèle les tendances observées sur le plan terminologique, perceptuel et structurel. Les participants emploient généralement des requêtes simples

  5. El Gobierno de la República en el exilio : crónica de un imposible retorno

    Directory of Open Access Journals (Sweden)

    Xavier Flores

    2001-01-01

    Full Text Available El triunfo de los aliados en la Segunda Guena Mundial hizo que los republicanos españoles exiliados en 1939 concibiesen esperanzas de un inmediato retomo de la República a su país con el apoyo aliado. Con esta idea se reconstituyeron las instituciones de la República Española en el exilio en México D. R, en agosto de 1945. En este artículo se analiza el proceso de esa reconstitución y los sucesivos gobiernos que se sucedieron hasta la disolución de las instituciones en junio de 1977, después de un imposible retorno.The victory of the salles in the Second World war did that the Spanish republicans exiled in 1939 were conceiving hopes ofan immediate return ofthe Republic to his(its country with the allied support. With this idea there were re-constituted the institutions of the Spanish Republic in the exile in México D.F., in August, 1945. In this article there are analyzed the process of this reconstitution and the successive governments that happened up to the dissolution of the institutions in June, 1977, afíer impossible I come back.

  6. Isolation of a minireplicon of the plasmid pG6303 of Lactobacillus plantarum G63 and characterization of the plasmid-encoded Rep replication protein

    Indian Academy of Sciences (India)

    Jing Fan; Xuedong Xi; Yan Huang; Zhongli Cui

    2015-06-01

    A cryptic 10.0-kb plasmid pG6303 from a multiplasmid-containing Lactobacillus plantarum G63 was studied. The analysis of replicon was facilitated by the construction of shuttle vectors and electrotransformation into L. plantarum. The pG6303 replicon included (i) an open reading frame encoding the putative Rep replication initiation protein; and (ii) the putative origin of replication. The Rep protein was expressed as a fusion with the hexa-histidine (His) at its C-terminal end and purified by Ni-affinity chromatography. The electrophoretic mobility shift assays in pG6303 showed that the purified Rep protein specifically bound from 5582 to 5945 bp, differing from the putative origin of replication of pG6303. We speculate that pG6303 replication is a new mode of plasmid replication.

  7. Functionalized silk assembled from a recombinant spider silk fusion protein (Z-4RepCT) produced in the methylotrophic yeast Pichia pastoris.

    Science.gov (United States)

    Jansson, Ronnie; Lau, Cheuk H; Ishida, Takuya; Ramström, Margareta; Sandgren, Mats; Hedhammar, My

    2016-05-01

    Functional biological materials are a growing research area with potential applicability in medicine and biotechnology. Using genetic engineering, the possibility to introduce additional functions into spider silk-based materials has been realized. Recently, a recombinant spider silk fusion protein, Z-4RepCT, was produced intracellularly in Escherichia coli and could after purification self-assemble into silk-like fibers with ability to bind antibodies via the IgG-binding Z domain. In this study, the use of the methylotrophic yeast Pichia pastoris for production of Z-4RepCT has been investigated. Temperature, pH and production time were influencing the amount of soluble Z-4RepCT retrieved from the extracellular fraction. Purification of secreted Z-4RepCT resulted in a mixture of full-length and degraded silk proteins that failed to self-assemble into fibers. A position in the C-terminal domain of 4RepCT was identified as being subjected to proteolytic cleavage by proteases in the Pichia culture supernatant. Moreover, the C-terminal domain was subjected to glycosylation during production in P. pastoris. These observed alterations of the CT domain are suggested to contribute to the failure in fiber assembly. As alternative approach, Z-4RepCT retrieved from the intracellular fraction, which was less degraded, was used and shown to retain ability to assemble into silk-like fibers after enzymatic deglycosylation. Copyright © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Gestión Integral en Puentes de carretera en la República de Cuba

    Directory of Open Access Journals (Sweden)

    Luis R. González Arestuche

    2006-01-01

    Full Text Available El logro de la seguridad en la circulación automotora es el problema básico a resolver en el proceso de conservación de la red de carreteras, partiendo de los aspectos que se vinculan con su explotación. Durante los diferentes movimientos de los vehículos, cada conductor precisa contar con las posibilidades técnicas de su equipo en cuanto a velocidad y capacidad de carga, tratando de realizar las operaciones con un gasto mínimo de tiempo, medios materiales y financieros, y con las mejores condiciones de confort y seguridad. El confort y seguridad del sistema de redes estará en función del estado técnico de la carretera en estudio y del sistema de gestión para su conservación. La premisa fundamental para la organización del servicio de mantenimiento, reparación y/o reconstrucción del sistema de carreteras, incluyendo sus puentes, se determinará atendiendo a los datos extraídos del inventario de toda la red vial existente en el territorio nacional. Para disponer de una Base de Datos confiable, que recoja con fiabilidad el estado técnico de la red vial y los puentes de carretera, se precisa de la combinación de las técnicas de inspección, levantamiento de patologías y diagnóstico del estado técnico de dicha red y sus puentes, unido a las técnicas de modelación e instrumentación que permitan realizar una correcta evaluación y un diagnóstico eficaz, además de contar con un excelente sistema de gestión de conservación en función del grado de deterioro de la red vial y de todos sus elementos componentes, incluyendo sus puentes. Este tipo de estudio y enfoque permite validar, con mayor grado de efectividad, las causas que propician el estado técnico del sistema vial y de los puentes de las carreteras, y a su vez posibilita realizar proyectos de rehabilitación, fiables y eficientes desde el punto de vista técnico. La República de Cuba en la actualidad sigue enfrentando la escasez de recursos materiales y financieros

  9. NASA Tech Briefs, November 1995. Volume 19, No. 11

    Science.gov (United States)

    1995-01-01

    The contents include: 1) Mission Accomplished; 2) Resource Report: Marshall Space Flight Center; 3) NASA 1995 Software of the Year Award; 4) Microbolometers Based on Epitaxial YBa2Cu3O(sub 7-x) Thin Films; 5) Garnet Random-Access Memory; 6) Fabrication of SNS Weak Links on SOS Substrates; 7) High-Voltage MOSFET Switching Circuit; 8) Asymmetric Switching for a PWM H-Bridge Power Circuit; 9) Better Ohmic Contacts for InP Semiconductor Devices; 10) Low-Bandgap Thermovoltaic Materials and Devices; 11) Digital Frequency-Differencing Circuit; 12) Imaging Magnetometer; 13) Computer-Assisted Monitoring of a Complex System; 14) Buffered Telemetry Demodulator; 15) Compact Multifunction Inspection Head; 16) Optical Detection of Fractures in Ceramic Diaphragms; 17) Eddy-Current Detection of Cracks in Reinforced Carbon/Carbon; 18) Apparent Thermal Conductivity of Multilayer Insulation; 19) Optimizing Misch-Metal Compositions in Metal Hydride Anodes; 20) Device for Sampling Surface Contamination; 21) Probabilistic Failure Assessment for Fatigue; 22) Probabilistic Fatigue and Flaw-Propagation Analysis; 23) Windows Program for Driving the TDU-850 Printer; 24) Subband/Transform MATLAB Functions for Processing Images; 25) Computing Equilibrium Chemical Compositions; 26) Program Processes Thermocouple Readings; 27) ICAN-Second-Generation Integrated Composite Analyzer; 28) Integrated Composite Analyzer with Damping Capabilities; 29) Computing Efficiency of Transfer of Microwave Power; 30) Program Calculates Power Demands of Electronic Designs; 31) Cost-Estimation Program; 32) Program Estimates Areas Required by Electronic Designs; 33) Program to Balance Mapped Turbopump Assemblies; 34) BiblioTech; 35) Controlling Mirror Tilt With a Bimorph Actuator; 36) Burst-Disk Device Simulates Effect of Pyrotechnic Device; 37) Bearing-Mounting Concept Accommodates Thermal Expansion; 38) Parallel-Plate Acoustic Absorbers for Hot Environments; 39) Adjustable-Length Strut Withstands Large Cyclic

  10. V-REP & ROS Testbed for Design, Test, and Tuning of a Quadrotor Vision Based Fuzzy Control System for Autonomous Landing

    OpenAIRE

    Olivares Mendez, Miguel Angel; Kannan, Somasundar; Voos, Holger

    2014-01-01

    This paper focuses on the use of the Virtual Robotics Experimental Platform (V-REP) and the Robotics Operative System (ROS) working in parallel for design, test, and tuning of a vision based control system to command an Unmanned Aerial Vehicle (UAV). Here, is presented how to configure the V-REP, and ROS to work in parallel, and how to use the developed packages in ROS for the pose estimation based on vision and for the design and use of a fuzzy logic control system. It is also shown in this ...

  11. Nueva Gerencia Pública en la Constitución de la República Bolivariana de Venezuela. Desafíos y perspectivas

    OpenAIRE

    Edith Cuñarro; Eduviges Morales; Nila Leal Gonzàlez

    2006-01-01

    El objetivo de este artículo es analizar la relación entre las bases institucionales del Estado establecidas en la Constitución de la República Bolivariana de Venezuela (1999) y algunos elementos propuestos por la Nueva Gerencia Pública (NGP). La metodología consiste en el estudio crítico de los principales planteamientos de la NGP y su viabilidad en el marco de la Constitución de la República Bolivariana de Venezuela (CRBV), así como el planteamiento de las carencias analíticas q...

  12. Examen de Auditoría Integral a la Dirección de Compras Públicas de la Vicepresidencia de la República

    OpenAIRE

    Balarezo Nuñez, Mariana de Jesus

    2014-01-01

    La auditoría integral practicada a la Dirección de Compras Públicas de la Vicepresidencia de la República del Ecuador se desarrolló considerando aspectos encaminados al análisis del control interno; al cumplimiento de las disposiciones legales, y demás normas aplicables en la entidad; y de las metas y objetivos propuestos; investigación que servirá de aporte para mejorar los sistemas de control administrativos y financieros de la Dirección de Compras Públicas de la Vicepresidencia de la Rep...

  13. Introducing the Clean-Tech Adoption Model: A California Case Study

    NARCIS (Netherlands)

    Bijlveld, P.C. (Paul); Riezebos, P. (Peter); Wierstra, E. (Erik)

    2012-01-01

    Abstract. The Clean-Tech Adoption Model (C-TAM) explains the adoption process of clean technology. Based on the Unified Theory of Acceptance and Usage of Technology (UTAUT) combined with qualitative research and empirical data gathering, the model predicts adoption based on the perceived quality, ef

  14. The institutional arrangements of innovation: Antecedents and performance effects of trust in high-tech alliances

    NARCIS (Netherlands)

    Jong, G. de; Klein Woolthuis, R.J.A.

    2008-01-01

    In this study we investigate the institutional arrangements of innovation processes in high-tech alliances, focusing on the role of trust. A major strength of the research is the opportunity to address antecedents as well as performance effects of trust. The antecedents of interorganizational trust

  15. The institutional arrangements of innovation : Antecendents and performance effects of trust in high-tech alliances

    NARCIS (Netherlands)

    de Jong, G.; Klein Woolthuis, R.

    2008-01-01

    In this study we investigate the institutional arrangements of innovation processes in high-tech alliances, focusing on the role of trust. A major strength of the research is the opportunity to address antecedents as well as performance effects of trust. The antecedents of interorganizational trust

  16. Contract research and high-tech alliances : Vistas for future studies

    NARCIS (Netherlands)

    de Jong, Gjalt; Woolthuis, Rosalinde J. A. Klein

    2008-01-01

    This research note addresses the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. Contract research is strongly heterogeneous, that is, many different paradigms, concepts, definitions and measures exist. We discuss the most im

  17. Silicon Valley: Planet Startup : Disruptive Innovation, Passionate Entrepreneurship & High-tech Startups

    NARCIS (Netherlands)

    Ester, P.; Maas, A.

    2016-01-01

    For decades now, Silicon Valley has been the home of the future. It's the birthplace of the world's most successful high-tech companies-including Apple, Yahoo, Google, Facebook, Twitter, and many more. So what's the secret? What is it about Silicon Valley that fosters entrepreneurship and innovation

  18. Are You What You Eat? An inside Look at High-Tech Food

    Science.gov (United States)

    Miller, Roxanne Greitz

    2007-01-01

    If we abide by the familiar saying "you are what you eat," it is understandable that people may be concerned with the incredible advances in food science technology and their possible impacts on human health. For example, in recent years high-tech scientific processes such as genetic modification, irradiation, and cloning have all been used to…

  19. SciTech Clubs for Girls. [Final report], September 1, 1991--April 30, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Malamud, E.; Diaz, O.; Cox, J.

    1994-12-31

    The program of SciTech Clubs for Girls and its progress are described. This is a program that promotes the learning of science and mathematics by girls in the age range of 9 to 13 years through the process of building exhibits and learning from local professionals. A list of exhibits and a critique of the program are given.

  20. AspenTech to Provide VPS for CNOOC-Shell Nanhai Petrochemicals Complex

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    @@ AspenTech, a US supplier of software and services to the process industries, recently announced it has been awarded a contract to supply a series of operator training simulators for the US$4.3 billion Nanhai Petrochemicals Project of CNOOC-Shell Petrochemical Company (CSPC)at Daya Bay in Huizhou City in South China's Guangdong Province.

  1. Determining Studies Conducted upon Individuals with Autism Spectrum Disorder Using High-Tech Devices

    Science.gov (United States)

    Eliçin, Özge; Kaya, Ali

    2017-01-01

    This study explores 67 experimental research articles written about children with Autism Spectrum Disorder using high-tech devices. The studies in this research were accessed through EBSCO, Academic Search Complete, ERIC, and Uludag University online search engines using keywords such as "autism and technology", "autism and…

  2. The Virginia Tech Shootings: Implications for Crisis Communication in Educational Settings

    Science.gov (United States)

    Barker, Gina G.; Yoder, Mollie E.

    2012-01-01

    By examining Virginia Tech's crisis communication during and after the shootings on April 16, 2007, valuable insights were gained that may be applied to current crisis communication models. This article addresses the unique characteristics of educational institutions and the need for comprehensive emergency communication strategies and on-site…

  3. Individualized Math Problems in Logarithms. Oregon Vo-Tech Mathematics Problem Sets.

    Science.gov (United States)

    Cosler, Norma, Ed.

    THis is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume includes problems involving logarithms, exponents, and…

  4. Single-tooth replacement by osseointegrated Astra Tech dental implants: a 2-year report

    DEFF Research Database (Denmark)

    Karlsson, U; Gotfredsen, K; Olsson, C

    1998-01-01

    This study presents the outcome of single-tooth restorations supported by Astra Tech single-tooth implants followed for 2 years. Forty-seven implants were placed in the same number of patients. Forty-three patients attended the second recall visit, and none of the evaluated implants have been...

  5. China’s comparative advantage still in low-tech manufacturing sector

    Institute of Scientific and Technical Information of China (English)

    文东伟; 冼国明

    2009-01-01

    This paper represents an attempt to estimate the level of vertical specialization in China’s manufacturing industry using China’s input-output tables (1995-2005) compiled by the OECD; describe the trends of evolution in the trade competitiveness of China’s manufacturing industry using the 1995-2006 trade data of 24 Chinese industries; and examine the key factors affecting the trade competitiveness of China’s manufacturing industry in accordance with the analytical framework of Hummels et al (2001). The estimation results indicate that i) the rapid increase in the vertical specialization levels of China’s merchandise sectors (especially the high-tech manufacturing sector) has to some extent explained the explosive growth of China’s exports (especially high-tech exports) in recent years; ii) there have been no substantive changes in China’s comparative advantages. Such advantages are still attributed to the low-tech manufacturing sector. However, the comparative advantage and trade competitiveness of the high-tech manufacturing sector have been on the rise; iii) vertical specialization has signif icantly enhanced the trade competitiveness of China’s manufacturing industry. Foreign market dependence, domestic intermediate input intensity and R&D intensity have an obvious promoting effect on the trade competitiveness of China’s manufacturing industry.

  6. Design of Demand Driven Return Supply Chain for High-Tech Products

    NARCIS (Netherlands)

    Ashayeri, J.; Tuzkaya, G.

    2010-01-01

    Many high-tech supply chain operate in a context of high process and market uncertainties due to shorter product life cycles. When introducing a new product, a company must manage the cost of supply, including the cost of returns over its short life cycle. The returns distribution looks like a negat

  7. New Horizontal Merger Guidelines Indicate Greater Scrutiny of High Tech and Pharmaceutical Transactions

    OpenAIRE

    Janet McDavid; Eric Stock

    2010-01-01

    It also indicates greater Agency scrutiny of such transactions in industries characterized by differentiated products and high levels of R&D spendingâ۠such as the high tech and pharmaceutical industries. Janet McDavid & Eric Stock (Hogan Lovells)

  8. TOOLS TO MINIMIZE RISK UNDER DEVELOPMENT OF HIGH-TECH PRODUCTS

    OpenAIRE

    AVDONIN BORIS N.; BATKOVSKY ALEXANDR M.; BATKOVSKY MIKHAIL A.

    2014-01-01

    The article describes the methodological bases and the economic and mathematical tools to minimize technological risks developing hightech products. A new, more efficient organization of the process of developing high-tech products, as well as tools for assessing the technical and economic efficiency of new technologies introduced on manufacturers of these products is offered.

  9. Investment in High-Tech Industries : An Example from the LCD Industry

    NARCIS (Netherlands)

    Huisman, K.J.M.; Kort, P.M.; Plasmans, J.E.J.

    2007-01-01

    This paper considers a representative firm taking investment decisions in a high-tech environment where different generations of products are invented over time. First, we develop a real options investment model in which, according to standard practice, the sales price and the unit production cost b

  10. Bazaarvoice: Applying Traditional Merger Analysis to a Dynamic High-Tech Market

    OpenAIRE

    James Fishkin

    2014-01-01

    No one should be surprised that the government will investigate mergers involving products in a high-tech industry utilizing the same Horizontal Merger Guidelines that apply to all merger investigationsâ۠regardless of the industry. James A. Fishkin (Dechert LLP)

  11. Virginia Tech business student and professor selected for GM Sullivan Program

    OpenAIRE

    Ho, Sookhan

    2004-01-01

    A student and a faculty member from Virginia Tech's Pamplin College of Business have been selected to participate in the GM Sullivan Fellowship Program that seeks to promote principles of corporate social responsibility developed by the late Rev. Leon H. Sullivan.

  12. Knowledge virtualization and local connectedness among smart high-tech companies

    NARCIS (Netherlands)

    Van Geenhuizen, M.S.; Nijkamp, P.

    2011-01-01

    Smart high-tech companies are characterized by knowledge intensity and open innovation. Even when these companies emerge in spatial clusters or dense urban places, they may utilize knowledge networks on a global scale. However, there is not much insight into the factors that shape knowledge networks

  13. Sims to Teen Second Life: Transition of the SimSavvy Girls to Tech Savvy Isle

    Science.gov (United States)

    Johnson, Barbara Z.; King, Elizabeth; Hayes, Elisabeth

    2008-01-01

    In its second year, the Tech Savvy Girls Project adopted "Teen Second Life" as a platform for interest-driven learning and designed projects and objects around themes important to them and their futures as technology-using, creative people. By using the building tools in an open-ended virtual world, they were able to pursue interests common to…

  14. Utilising "Low Tech" Analytical Frameworks to Analyse Dyslexic Caribbean Students' Classroom Narratives

    Science.gov (United States)

    Blackman, Stacey

    2007-01-01

    The cognitions of Caribbean students with dyslexia are explored as part of an embedded multiple case study approach to teaching and learning at two secondary schools on the island of Barbados. This exploration employed "low tech" approaches to analyse what pupils had said in interviews using a Miles and Huberman (1994) framework.…

  15. The content and role of formal contracts in high-tech alliances

    NARCIS (Netherlands)

    Jong, G. de; Klein Woolthuis, R.J.A.

    2009-01-01

    In this study we investigate the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. The design of a formal agreement is one of the most important strategic decisions for alliance partners. Drawing upon transaction cost arguments

  16. Student chefs debut at Virginia Tech's Donaldson Brown Hotel and Conference Center

    OpenAIRE

    Felker, Susan B.

    2004-01-01

    The leap from graduation to that first full-time job is often daunting to college seniors, but that transition will be much easier for students in the Department of Hospitality and Tourism Management (HTM) program at Virginia Tech's Pamplin College of Business, thanks to hands-on labs at the university's Donaldson Brown Hotel and Conference Center.

  17. Virginia Tech Residence Hall Federation recognized with multiple awards at annual conference

    OpenAIRE

    Gehrt, Katie

    2009-01-01

    On Feb. 8, 2009, the Virginia Tech Residence Hall Federation took home five awards at the 2009 Virginia Association of College and University Residence Halls (VACURH) conference, held this year at The University of Virginia-Wise, located in Wise, Va.

  18. Application Model of New Agricultural Hotline Sci-tech Information Service System in Beijing

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    To further promote information construction in rural areas and popularize agricultural information service,we introduced the content of new agricultural hotline sci-tech information service system construction,summed up application effect of the system,analyzed advantages and existing problems in the system development,and put forward countermeasures for its further development.

  19. [Ways to optimize working conditions of medical personnel servicing modern hi-tech medical equipment].

    Science.gov (United States)

    Kravchenko, O K

    2007-01-01

    The author analyzed health state of medical personnel through various parameters. Hygienic characteristics of work conditions for medical personnel subjected to physical factors when servicing modern hi-tech medical equipment are presented. Occupational groups at high risk are defined. The article covers main directions in improving work conditions and preserving health for medical personnel in these groups.

  20. The Virginia Tech Shootings: Implications for Crisis Communication in Educational Settings

    Science.gov (United States)

    Barker, Gina G.; Yoder, Mollie E.

    2012-01-01

    By examining Virginia Tech's crisis communication during and after the shootings on April 16, 2007, valuable insights were gained that may be applied to current crisis communication models. This article addresses the unique characteristics of educational institutions and the need for comprehensive emergency communication strategies and on-site…

  1. A World of Competitors: Assessing the US High-Tech Advantage and the Process of Globalisation

    Science.gov (United States)

    Douglass, John Aubrey

    2008-01-01

    Research universities throughout the world are part of a larger effort by countries to bolster science and technological innovation and compete economically. The United States remains highly competitive as a source of high-tech innovation because of a number of market positions, many the results of long-term investments in institutions (such as…

  2. New partnership between Virginia Tech Transportation Institute and Center for Injury Biomechanics receives first research grant

    OpenAIRE

    Box, Sherri

    2009-01-01

    A team of three Virginia Tech faculty members -- Stefan Duma, Warren Hardy, and H. Clay Gabler -- was recently awarded $2.6 million from U.S. Army Research Acquisition Activity to study the biomechanics of head, neck, and chest injury prevention for soldiers.

  3. The content and role of formal contracts in high-tech alliances

    NARCIS (Netherlands)

    de Jong, Gjalt; Woolthuis, Rosalinde Ja Klein

    2009-01-01

    In this study we investigate the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. The design of a formal agreement is one of the most important strategic decisions for alliance partners. Drawing upon transaction cost arguments

  4. Organizational Attributes and Learning beyond the Boundaries: Comparative Case Studies of Two High-Tech Firms

    Science.gov (United States)

    Zhong, Jing; Wu, Sizong; Li, Jun

    2008-01-01

    This study compares two high-tech firms in terms of their differences in organizational characteristics and learning activities beyond the boundaries. It finds that the larger company continuously develops new technology to achieve long-term survival through a balance between exploration and exploitation while the smaller enterprise grows quickly…

  5. Reformulating General Engineering and Biological Systems Engineering Programs at Virginia Tech

    Science.gov (United States)

    Lohani, Vinod K.; Wolfe, Mary Leigh; Wildman, Terry; Mallikarjunan, Kumar; Connor, Jeffrey

    2011-01-01

    In 2004, a group of engineering and education faculty at Virginia Tech received a major curriculum reform and engineering education research grant under the department-level reform (DLR) program of the NSF. This DLR project laid the foundation of sponsored research in engineering education in the Department of Engineering Education. The DLR…

  6. Restructuring Student Experiences Using Tech Prep Mapping To Integrate Vocational and Academic Curriculum.

    Science.gov (United States)

    Pirozzoli, Don

    The growing emphasis on accountability and the demand for better prepared students is pressing institutions of higher education to examine restructuring. Student experiences represent an important arena for school restructuring, and a useful approach to changing student experiences is the Tech Prep Mapping (TPM) process. The TPM process requires…

  7. Virginia Tech's Leonard K. Peters To Head Pacific Northwest National Laboratory

    OpenAIRE

    Trulove, Susan

    2003-01-01

    Leonard K. Peters, vice provost for research at Virginia Tech, will become Battelle senior vice president and director of the Pacific Northwest National Laboratory in Richland, Wash. The announcement was issued at time today by Carl Kohrt, CEO of Battelle. Peters assumes his new position on April 1.

  8. Virginia Tech's Board Of Visitors Appointed Two College Of Natural Resources Professors To Professorships

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The Virginia Tech Board of Visitors has appointed Donald Orth the Thomas H. Jones Professor of Fisheries and Wildlife Sciences and Frederick Kamke the Thomas M. Brooks Professor of Wood Sciences and Forest Products. Orth and Kamke are on the faculty of the College of Natural Resources.

  9. Spaces of Innovation: Experiences from Two Small High-Tech Firms

    Science.gov (United States)

    Heiskanen, Tuula; Heiskanen, Hannu

    2011-01-01

    Purpose: By comparing two small high-tech firms specialising in medical technology this article seeks to answer the following questions: What are the key characteristics of innovation processes in the case firms? How do the mutual relationships between mental, social and physical spaces explain the different pathways in the innovation processes in…

  10. Design of Demand Driven Return Supply Chain for High-Tech Products

    NARCIS (Netherlands)

    Ashayeri, J.; Tuzkaya, G.

    2010-01-01

    Many high-tech supply chain operate in a context of high process and market uncertainties due to shorter product life cycles. When introducing a new product, a company must manage the cost of supply, including the cost of returns over its short life cycle. The returns distribution looks like a

  11. Firmino Costa, un intelectual de la República y sus propósitos educativos (1907-1937

    Directory of Open Access Journals (Sweden)

    Juliana Cesário Hamdan

    2014-01-01

    Full Text Available El presente artículo pretende analizar la actu - ación del educador Firmino Costa, nacido en Minas Gerais, al retomar sus antecedentes his - tóricos que se localizan en la base de las formas de su actuación política e intelectual. Para este análisis, recurrimos al trabajo de Alonso (2008, 1 Oliveira (1999 2 y Carvalho (2003, 3 considera - mos las expresivas contribuciones para su com - prensión en relación con la historia e ideas que circularon en este periodo, comprendido entre los años que antecedieron a las primeras déca - das de la Proclamación de la República en Brasil (I889. Las tres obras, pese a que se escribieron a partir de objetos y objetivos distintos, refuta - ron interpretaciones que, por un lado, tratan el escenario intelectual de la República por medio de tipologías de intelectuales, que estarían ab - sorbiendo pasivamente las teorías europeas y norteamericanas. Y, por otro lado, las que son marcadas por estudios que enfatizan las acciones individuales, empeñadas en llevar adelante sus banderas ideológicas. Al contrario, los autores entienden que los sujetos están inmersos en de - terminado entorno cultural, constituido por las redes de sociabilidad y por el repertorio de ideas en circulación y, por eso mismo, tienen formas distintas de actuación política e intelectual. Y ese escenario condiciona, en gran medida, las posi - bilidades de actuación. Así, este artículo busca establecer conexiones entre algunos elementos del escenario cultural, presentes en los años que antecedieron y en los que sucedieron a la República, relacionándolos a las formas de actuación política e intelectual que informan la acción educacional del educador minero. Ese movimiento analítico, por su vez, exigió que recorriésemos a algunas de las formu - laciones teóricas de Antonio Gramsci, en lo que se refiere a los sentidos de actuación de los inte - lectuales, como forma de comprenderlos a partir del contexto y de las

  12. Practice and Exploration of Rural Sci-tech Service Supermarket:A Case Study of Jurong Economic Forest and Fruit Industrial Branch

    Institute of Scientific and Technical Information of China (English)

    Weizhong; LIU; Yabo; LIU; Jianying; ZHANG; Nini; MAO; Zhijian; WANG

    2013-01-01

    The rural sci-tech supermarket in Jiangsu Province is an innovative model of rural sci-tech service. With reference to the concept of modern commodity supermarket, this model integrates variety, technology and achievement information into the sci-tech supermarket platform, provides various agricultural sci-tech services, and improves farmers recognition and acceptance of science and technology, so as to accelerate conversion of scientific and technological achievements and demonstration and popularization of new varieties, new technologies and new models. This paper analyzes practice of Jurong economic forest and fruit industrial branch and presents recommendations for building Jiangsu rural sci-tech service supermarket.

  13. Od bazy bibliograficznej do pe?notekstowej ? wsp??praca og?lnopolskiego Konsorcjum BazTech

    OpenAIRE

    2015-01-01

    W artykule przedstawiono baz? BazTech indeksuj?c? zawarto?? polskich czasopism technicznych. W szczeg?lno?ci om?wiono: zas?b bazy, rodzaje rekord?w, sposoby dost?pu i prezentacji zawartych w bazie informacji. Om?wiono etapy przekszta?cania bazy z bibliograficznej-abstraktowej w pe?notekstow?. Zaprezentowano tw?rc?w bazy czyli wsp??pracuj?ce, od prawie 20 lat, tworz?ce Konsorcjum BazTech, biblioteki wy?szych uczelni technicznych i instytut?w naukowych. The article presents the BazTech da...

  14. Co-producción de conocimiento en la integralidad. Montevideo: Universidad de la República

    Directory of Open Access Journals (Sweden)

    Cecilia Montes

    2015-11-01

    Full Text Available El libro Co-producción de conocimiento en la integralidad es organizado por el equipo docente de la Unidad de Apoyo a la Extensión y Actividades en el Medio (UAExAM de la Facultad de Psicología de la Universidad de la República (UdelaR. El proceso de producción del texto cuenta con un equipo de comité académico integrado por los Profesores Agregados Humberto Tommasino, Gabriel Kaplún y Gabriela Etchebehere. Además cuenta con un comité editor compuesto por los docentes asistentes, Javier Romano y Sandra Fraga, y la ayudante Valeria Cavalli. Ambos equipos realizan las revisiones para la selección de los artículos publicados.

  15. Alejandro Bunge y el problema de la vivienda obrera en la República Argentina (1910-1915

    Directory of Open Access Journals (Sweden)

    Jorge A. Núñez

    2010-02-01

    Full Text Available Este trabajo pretende indagar, a partir del estudio de la figura del economista Alejandro Bunge, en la problemática de la vivienda obrera en la República Argentina en las primeras décadas de la pasada centuria. Aquí se argumentará que los estudios realizados porAlejandro Bunge como director de la División Estadísticas del Departamento Nacional de Trabajo en el período 1910-1915 contribuyeron de manera notable a la elaboración del proyectoy posterior sanción de la Ley de Casas Baratas para Obreros (n°9677.

  16. Indalecio Prieto enjuicia el papel del Gobierno de la República en el estallido de la Guerra Civil

    Directory of Open Access Journals (Sweden)

    Antonio Marquina

    2006-10-01

    Full Text Available El documento que procedemos a transcribir es una grabación efectuada por Indalecio Prieto el 28 de marzo de 1961 en la casa de los esposos Rafael y Guillermina Supervía, en Washington. La grabación se puede dividir en cuatro partes. Una primera, de introducción, donde Prieto narra cómo fue invitado a México y el anhelo por volver a España de los republicanos exiliados. Luego la narración de los acontecimientos del 14 de abril con la instauración de la II República. El tercer apartado se refiere al pronunciamiento militar del 17 de julio, que enlaza con la última parte del documento relativa a la opinión de Prieto sobre Manuel Azaña.

  17. [Characterization of rhizobia causing nodules on leguminous trees native to Uruguay using the rep-PCR technique].

    Science.gov (United States)

    Rodríguez, A; Frioni, L

    2003-01-01

    Methods for identifying and following microorganisms in the environment such as soils, water and plant association have been highly developed in recent years. In this study, we used rep-PCR for the characterization of Rhizobium bacteria isolated from legume trees native of Uruguay which permitted to follow them in plant inoculation assays. Among the primers used, ERIC and BOX1AR, the latter allowed the differentiation of isolates from different legumes and the finding of a high level of homology among rhizobia that nodulate the same legume species. Besides, it demonstrated that the profiles of the isolates recovered from nodules of Acacia caven, were identical to the ones used as inoculants; this confirmed the efficiency of these methods to follow these diazotrophs in the environment.

  18. La psicología en la república federal Alemana: situación actual de la disciplina

    Directory of Open Access Journals (Sweden)

    Edgar Heineken

    1979-01-01

    Full Text Available Se presentan datos sobre la situación actual de la psicología como ciencia y como profesión en la República Federal Alemana. Se muestra la distribución temática de las actividades de investigación y la dinámica de la comunicación científica, así como el número de estudiantes de psicología en los últimos años y la situación universitaria en lo que atañe al profesorado y estudiantado. Se explica además la situación de la psicología como profesión analizando la distribución de los psicólogos en las diferentes áreas profesionales.

  19. Barrio Adentro en Salud: un proyecto político y social de la República Bolivariana de Venezuela

    OpenAIRE

    Virginia Aguirre

    2008-01-01

    Este trabajo intenta sistematizar un proceso histórico muy complejo que vive la República Bolivariana de Venezuela, donde la participación protagónica de la comunidad está marcando una pauta en la transformación política y social. La implementación de la red de atención primaria del nuevo Sistema Público Nacional de Salud, cuya expresión es la Misión Barrio Adentro, es uno de los logros de significativa trascendencia en salud. Se trata de un proyecto político de inclusión social donde se est...

  20. Cuba: el advenimiento de la República en el periódico La Lucha, 1902

    OpenAIRE

    María del Rosario Rodríguez Díaz

    2014-01-01

    El establecimiento de la primera república de cuba, en mayo de 1902, ha sido un tema escasamente abordado en la historiografía cubana contemporánea. Por ello, en el pre- sente artículo nos proponemos analizar esta coyuntura histórica a través del discurso periodístico del diario la lucha, órgano dirigido a un público bilingüe, acorde a las exigencias del nuevo poder foráneo. Pretendemos estudiar la problemática existente durante el periodo de transi- ción y el inicio de la era republicana en ...

  1. Genetic relationships between sympatric populations of Bacillus cereus and Bacillus thuringiensis, as revealed by rep-PCR genomic fingerprinting

    Directory of Open Access Journals (Sweden)

    Ana Paula S Peruca

    2008-08-01

    Full Text Available The bacterial strain Bacillus cereus is closely related to Bacillus thuringiensis, although any genetic relationship between the two strains is still in debate. Using rep-PCR genomic fingerprinting, we established the genetic relationships between Brazilian sympatric populations of B. cereus and B. thuringiensis simultaneously collected from two geographically separate sites. We observed the formation of both B. thuringiensis and B. cereus clusters, as well as strains of B. cereus that are more closely related to B. thuringiensis than to other B. cereus strains. In addition, lower genetic variability was observed among B. thuringiensis clusters compared to B. cereus clusters, indicating that either the two species should be categorized as separate or that B. thuringiensis may represent a clone from a B. cereus background.

  2. Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence.

    Science.gov (United States)

    Bönsch, D; Lederer, T; Reulbach, U; Hothorn, T; Kornhuber, J; Bleich, S

    2005-04-01

    Various studies have linked alcohol dependence phenotypes to chromosome 4. One candidate gene is NACP (non-amyloid component of plaques), coding for alpha synuclein. Recently, it has been shown that alpha synuclein mRNA is increased in alcohol-dependent patients within withdrawal state. This increase is significantly associated with craving, especially obsessive craving. On the basis of these observations, the present study analysed two polymorphic repeats within the NACP gene. We found highly significant longer alleles of NACP-REP1 in alcohol-dependent patients compared with healthy controls (Kruskal-Wallis test, chi(2)=99.5; df=3, Pcraving, a key factor in the genesis and maintenance not only of alcoholism but also of addiction in general.

  3. La cuestión autonómica en el PSOE durante la II República

    Directory of Open Access Journals (Sweden)

    Daniel Molina Jiménez

    2014-10-01

    Full Text Available El debate sobre la cuestión regional en el PSOE durante la II República española fue muy amplio. Existe una lucha entre una concepción centralista y otra federal, en cualquier caso, ambas van a estar vinculadas en el discurso de los socialistas a los intereses de la clase obrera. Palabras clave: Federalismo, centralismo, Estado, nacionalismo, trabajadores. ______________________Abstract:The debate on the issue in the PSOE regional during the Second Spanish Republic was very wide. There is a fight between a centralized approach and other federal, in any case, both are going to be linked in the speech of the socialists to the interests of the working class.  Keywords: Federalism and centralist State, nationalism, workers.  

  4. Arte antioqueño en la colección del Banco de la República

    Directory of Open Access Journals (Sweden)

    Santiago Londoño Vélez

    2007-01-01

    Full Text Available Hace cincuenta años, la Biblioteca Luis Ángel Arango del Banco de la República adquirió la primera pintura con la que inició su colección de arte colombiano y latinoamericano que hoy se puede apreciar en la Manzana Cultural. Se trata del óleo del pintor antioqueño Fernando Botero titulado En rojo y azul. Este hecho y la muy buena representación de arte antioqueño que se encuentra en sus salas, me animan a trazar a mano alzada su evolución y a señalar algunos elementos que contribuyan a su mejor comprensión.

  5. Aliados, tránsfugas y barrilitos: las elecciones legislativas de 2010 en República Dominicana

    Directory of Open Access Journals (Sweden)

    Ana Belén BENITO SÁNCHEZ

    2011-03-01

    Full Text Available Este artículo analiza las claves explicativas de los resultados de las elecciones legislativas y municipales de 2010 en República Dominicana así como de la reciente transformación que ha experimentado el sistema de partidos dominicano, del tripartidismo al bipartidismo plural. El liderazgo del presidente Leonel Fernández, su imagen, popularidad y pragmatismo son la clave del éxito electoral del PLD, favorecido también por el faccionalismo endémico del PRD y la descomposición progresiva del PRSC. En esta contienda, el PLD consolida su dominio electoral gracias al apoyo de los partidos minoritarios y se asegura el control del Legislativo durante los próximos seis años.

  6. Breves reflexiones en torno al control externo administrativo y sus consecuencias en la República Argentina

    Directory of Open Access Journals (Sweden)

    Miriam Mabel Ivanega

    2010-03-01

    Full Text Available Este artículo contiene una reflexión sobre la Ley 24.156 sobre administración financiera y sistemas de control de la República Argenti na, que puede ser aplicable a otros países. El control público externo debe, de un lado, no sólo exigir el cumplimiento de la ley sino ser también el primero en cumplirla y, por otro,  debe ser útil  a la sociedad, es decir, comprometerse con el bien común y en forma más es pecífica,   ser  efectivo,   independiente,   transparente  y oportuno.

  7. Influence of retinoblastoma-related gene silencing on the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana benthamiana plants

    Directory of Open Access Journals (Sweden)

    Bruce Gareth

    2011-12-01

    Full Text Available Abstract Background Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to reprogramme host cellular machinery for DNA replication. This process is thought to be mediated by inactivation of cell-cycle repressor proteins and by induction of host DNA synthesis protein expression through actions of the geminviral replication initiator protein (Rep. Findings Exploiting a Nicotiana benthamiana pOri2 line, which is transformed with a transgene consisting of a direct repeat of the African cassava mosaic virus (ACMV-replication origin (Ori flanking a non-viral DNA region, and virus-induced RNA silencing (VIGS, the impact of host gene expression on replication of the ACMV-derived replicon was investigated. The ACMV Rep trans-replicated the viral episomal replicon in leaves of young but not older pOri2 plants. Upon VIGS-mediated down-regulation of N. benthamiana NbRBR1, the retinoblastoma-related protein gene coding for a negative cell-cycle suppressor, recovered the ability of ACMV Rep for trans DNA replication, whereas the silencing of NbPCNA coding for the sliding clamp of DNA polymerase had no effect. Conclusions These results suggest that the cellular machinery for DNA replication in differentiated tissues of older leaves cannot be reprogrammed by Rep alone but may need other uncharacterised viral and plant factors.

  8. [Valitsusliidus olevad Reformierakond ning Isamaa ja Res Publica Liit on kavandatava koolireformi suhtes eri meelt] / Mailis Reps, Tiiu Kuurme, Karin Kütt

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2010-01-01

    Reformierakonna ettepaneku kohta jätta omavalitsustele õiguse otsustada, kas gümnaasium ja põhikool lahutatakse või jätkatakse ühendkooliga avaldavad arvamust riigikogu liige Mailis Reps, Tallinna Ülikooli dotsent Tiiu Kuurme ja Rannu keskkooli direktor Karin Kütt

  9. Elecciones 2016 en República Dominicana: Características, desafíos y retos desde la perspectiva electoral

    Directory of Open Access Journals (Sweden)

    Roberto Rosario Márquez

    2015-01-01

    Full Text Available Expone la reforma electoral del año 2010, los aspectos importantes que se presentaron en las elecciones de 2012 y los retos que la Junta Central Electoral de la República Dominicana enfrenta en la organización y administración del proceso electoral del año 2016

  10. Multi-Locus Sequence Typing (MLST) and Repetitive Extragenic Palindromic Polymerase Chain Reaction (REP-PCR), characterization of shigella spp. over two decades in Tianjin China

    Science.gov (United States)

    Cao, Yang; Wei, Dianjun; kamara, Idrissa L; Chen, Wei

    2012-01-01

    To understand the change of the dominant serogroup of Shigella spp., their antimicrobial resistance over more than two decades in Tianjin, their phylogenetic similarity and to determine their evolutionary biology by using REP-PCR and MLST in order to study their epidemiological character. Multi-locus Sequence Typing was performed to determine their lineage and phylogenetic similarity. REP-PCR typing was used to study the homology of their genomic DNA. The isolated rate of group D Shigella in 2009 and 2010 had obviously increased. Antimicrobial susceptibility test results showed that the resistant rates of the 1981-1983 Shigella flexneri to tetracycline, streptomycin and chloramphenicol varied from 76.47 to 100%, they were all sensitive to other antibiotics. During 2009-2010, the resistance rates of the isolated Shigella flexneri to gentamicin, amikacin, third and fourth Generation Cephalosporins and quinolones had increased. MLST results produced five sequence types and two sequence type complexes. REP-PCR showed DNA band similarities between the 1981-1983 and 2009-2010 strains. The dominant serogroup of Shigella in Tianjin has changed from Shigella flexneri to Shigella sonnei. Increased drug resistance of Shigella flexneri is higher than Shigella sonnei because a great variety of antibiotics has been used. The MLST results showed that the 1981-1983 strains had the same sequence type with some of the 2009-2010 strains. Combination of MLST and REP-PCR produced better discriminatory power than using either method alone. PMID:23205184

  11. [Valitsusliidus olevad Reformierakond ning Isamaa ja Res Publica Liit on kavandatava koolireformi suhtes eri meelt] / Mailis Reps, Tiiu Kuurme, Karin Kütt

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2010-01-01

    Reformierakonna ettepaneku kohta jätta omavalitsustele õiguse otsustada, kas gümnaasium ja põhikool lahutatakse või jätkatakse ühendkooliga avaldavad arvamust riigikogu liige Mailis Reps, Tallinna Ülikooli dotsent Tiiu Kuurme ja Rannu keskkooli direktor Karin Kütt

  12. Repše: välislaenuabi katkedes on aasta lõpuks raha läbi / Mikk Salu

    Index Scriptorium Estoniae

    Salu, Mikk, 1975-

    2009-01-01

    Läti rahandusminister Einars Repše hoiatas, et kui Lätil ei õnnestu täita oma kohustusi rahvusvaheliste kreeditoride ees ja vähendada 2010. a. eelarvedefitsiiti poole miljardi lati võrra, võib riigikassa rahast tühjaks joosta juba enne aasta lõppu

  13. Avances y desafíos en los regímenes electorales: América Central y República Dominicana

    Directory of Open Access Journals (Sweden)

    Hugo Picado León

    2015-01-01

    Full Text Available Este artículo resume los principales temas tratados en el Seminario Internacional Elecciones en América Central y República Dominicana. Se subraya el aporte de los organismos electorales en los procesos de transición a la democracia y sus principales desafíos en la actualidad

  14. Macau no Contexto da Estratégia de Integração da República Popular da China no Mercado Mundial

    OpenAIRE

    Murteira, Mário

    1994-01-01

    Série II Especulação sobre o futuro de Macau perante a forte estratégia de intergração da República Popular da China no mercado mundial (com o desempenho de um papel influente por parte de Macau e Taiwan).

  15. Variation in extragenic repetitive DNA sequences in Pseudomonas syringae and potential use of modified REP primers in the identification of closely related isolates

    Directory of Open Access Journals (Sweden)

    Elif Çepni

    2012-01-01

    Full Text Available In this study, Pseudomonas syringe pathovars isolated from olive, tomato and bean were identified by species-specific PCR and their genetic diversity was assessed by repetitive extragenic palindromic (REP-PCR. Reverse universal primers for REP-PCR were designed by using the bases of A, T, G or C at the positions of 1, 4 and 11 to identify additional polymorphism in the banding patterns. Binding of the primers to different annealing sites in the genome revealed additional fingerprint patterns in eight isolates of P. savastanoi pv. savastanoi and two isolates of P. syringae pv. tomato. The use of four different bases in the primer sequences did not affect the PCR reproducibility and was very efficient in revealing intra-pathovar diversity, particularly in P. savastanoi pv. savastanoi. At the pathovar level, the primer BOX1AR yielded shared fragments, in addition to five bands that discriminated among the pathovars P. syringae pv. phaseolicola, P. savastanoi pv. savastanoi and P. syringae pv. tomato. REP-PCR with a modified primer containing C produced identical bands among the isolates in a pathovar but separated three pathovars more distinctly than four other primers. Although REP-and BOX-PCRs have been successfully used in the molecular identification of Pseudomonas isolates from Turkish flora, a PCR based on inter-enterobacterial repetitive intergenic concensus (ERIC sequences failed to produce clear banding patterns in this study.

  16. Un ministro para la Defensa de la República desde el exilio : Juan Hernández Saravia

    Directory of Open Access Journals (Sweden)

    Manuela Aroca Mohedano

    2004-01-01

    Full Text Available La nueva situación internacionai surgida tras el final de la II Guerra Mundial propició la recuperación de las instituciones republicanas españolas en el exilio. Juan Hernández Saravia, un militar profesional, azañista y republicano, será el ministro de la Defensa Nacional de la República Española. Entre posibilidades reales y utopías, a caballo entre la defensa a ultranza de la legalidad y la protección de los movimientos clandestinos antifranquistas, en medio de las disensiones de los militares exiliados dispersos en varios continentes, discurrirá la actuación de un Ministerio que tendrá como objetivo principal la recuperación del ejército para la futura restaurada República y que verá truncadas sus expectativas por la aparición en el panorama mundial de los primeros.A Minister in exile for tfie Republic Defence: Juan Hernández Saravia The new International situation arisen after the end of the Second World War led to the recovery of Spanish Republic Institutions in exile. Juan Hernández Saravia, an army officer, republican and adherent to Azaña, became the National Defence Minister of Spanish Republic. Among real possibilities and utopia, halfway between a vigorous legality defence and the protection of clandestino movements against Franco's dictatorship, the main objective of this Ministery was the army recovery for the futuro restoring Republic, but the early Cold War shattered these prospects.

  17. A comprehensive computational study on pathogenic mis-sense mutations spanning the RING2 and REP domains of Parkin protein.

    Science.gov (United States)

    Biswas, Ria; Bagchi, Angshuman

    2017-04-30

    Various mutations in PARK2 gene, which encodes the protein parkin, are significantly associated with the onset of autosomal recessive juvenile Parkinson (ARJP) in neuronal cells. Parkin is a multi domain protein, the N-terminal part contains the Ubl and the C-terminal part consists of four zinc coordinating domains, viz., RING0, RING1, in between ring (IBR) and RING2. Disease mutations are spread over all the domains of Parkin, although mutations in some regions may affect the functionality of Parkin more adversely. The mutations in the RING2 domain are seen to abolish the neuroprotective E3 ligase activity of Parkin. In this current work, we carried out detailed in silico analysis to study the extent of pathogenicity of mutations spanning the Parkin RING2 domain and the adjoining REP region by SIFT, Mutation Accessor, PolyPhen2, SNPs and GO, GV/GD and I-mutant. To study the structural and functional implications of these mutations on RING2-REP domain of Parkin, we studied the solvent accessibility (SASA/RSA), hydrophobicity, intra-molecular hydrogen bonding profile and domain analysis by various computational tools. Finally, we analysed the interaction energy profiles of the mutants and compared them to the wild type protein using Discovery studio 2.5. By comparing the various analyses it could be safely concluded that except P437L and A379V mutations, all other mutations were potentially deleterious affecting various structural aspects of RING2 domain architecture. This study is based purely on computational approach which has the potential to identify disease mutations and the information could further be used in treatment of diseases and prognosis. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Differentiation of banding patterns between Streptococcus mutans and Streptococcus sobrinus isolates in rep-PCR using ERIC primer

    Science.gov (United States)

    Okada, Tamami; Takada, Kazuko; Fujita, Kou; Ikemi, Takuji; Osgood, Robert C.; Childers, Noel K.; Michalek, Suzanne M.

    2011-01-01

    Background Streptococcus mutans and Streptococcus sobrinus are considered to be important bacterial species in the initiation of human dental caries. Therefore, the establishment of a reliable genotyping method to distinguish S. mutans from S. sobrinus is of central importance. Objective We assessed the usefulness of repetitive extragenic palindromic polymerase chain reaction (rep-PCR) using ERIC primer banding patterns in differentiating S. mutans and S. sobrinus. Design Five S. mutans and two S. sobrinus prototype strains and 50 clinical isolates (38 S. mutans serotype c, 4 S. sobrinus serotype d, and 8 S. sobrinus serotype g) were examined. The banding patterns of amplicons generated were compared among the prototype strains and clinical isolates, to find common bands that distinguish S. mutans and S. sobrinus. Results Multiple banding patterns were seen with all strains tested. The representative strains of S. mutans tested revealed six unique, strong bands at 2,000 bp, 1,700 bp, 1,400 bp, 1,100 bp, 850 bp, and 250 bp, whereas S. sobrinus had seven strong bands at 2,000 bp, 1,800 bp, 1,100 bp, 900 bp, 800 bp, 600 bp, and 550 bp. The band at 1,100 bp was the only band that was observed in both S. mutans and S. sobrinus. Furthermore, most clinical S. mutans isolates revealed identical banding patterns. All S. mutans had amplicons at 1,700 bp, 850 bp, and 250 bp, whereas those of S. sobrinus were at 1,100 bp, 900 bp, and 800 bp. Conclusions These results indicate that using rep-PCR with the ERIC primers can distinguish between S. mutans and S. sobrinus. PMID:22145074

  19. Maquiavel Versus Rousseau: as Divisões Sociais e Seu Papel em uma República Bem-Ordenada

    Directory of Open Access Journals (Sweden)

    Renato Moscateli

    2015-01-01

    Full Text Available RESUMO:As relações de conflito entre os grupos sociais constituem um tópico relevante para a filosofia política, e as maneiras distintas como elas são interpretadas dependem de uma visão mais ampla sobre as condições apropriadas a um Estado bem-ordenado. Maquiavel, por exemplo, ao refletir sobre o caso da Roma Antiga, procurou refutar aqueles que condenavam os tumultos entre os nobres e a plebe da cidade, como se eles tivessem provocado apenas males à república. Para o autor, tais tumultos estavam entre as principais causas da liberdade romana, visto que a diferença nos “humores” dos grandes e do povo resultou em embates que deram origem às leis favoráveis à liberdade. Rousseau, por sua vez, descreveu a existência de “associações particulares” dentro da sociedade civil como algo potencialmente nocivo à harmonia da república, pois cada uma delas contém um interesse particular passível de se sobrepor ao bem comum, nas deliberações públicas, prejudicando o prevalecimento da vontade geral. Ainda para o genebrino, a ocorrência de longos debates e de tumultos nas assembleias populares poderia ser um sinal de divisões internas capazes de ocasionar a ruína do Estado. Frente a essas duas maneiras de conceber o papel político dos conflitos sociais, o objetivo deste trabalho é realizar uma análise comparativa das ideias de Maquiavel e de Rousseau.

  20. 中小企业技术创新对成长性影响——科技型企业不同于非科技型企业?%Impact of tech - innovation on growth : are high - tech SMEs different from non - high - tech SMEs?

    Institute of Scientific and Technical Information of China (English)

    陈晓红; 马鸿烈

    2012-01-01

    Tech innovation has important meaning on the growth of high - tech and non - high - tech SMEs, based on 437 Chinese lis- ted SMEs, this paper initial build tech - innovation model to these two types of enterprise respectively, and analyze impact of their tech - innovation on growth. Result shows that greater R&D intensity, better enterprise tech - innovation environment, more patent number and greater human resource input, the better of SMEs tech - innovation ability; for high - teeh SMEs, relationship between tech - inno- vation and growth is linear, while for non - high - tech SMEs, the relevance is not obvious, for this situation, combining practical con- dition, this paper provide advice for SMEs development.%技术创新对科技型和非科技型中小企业成长性的作用具有一定重要意义,基于414家中小上市公司数据,本文首次针对两类企业分别构建了技术创新模型,分析技术创新对二者成长性的影响。结果表明:研发投人程度越大,企业创新环境越好,专利数量越多,人力资源的投入强度越大的中小企业技术创新能力越强;对于科技型中小企业,其技术创新与成长性呈显著正相关关系,而非科技型中小企业其相关性不明显,针对该情况,本文结合实际现状对中小企业的发展提出了建议。

  1. 区域科技创新与科技金融耦合协调度评价研究%Research on Coupling Coordinated Degree Evaluation of Regional Sci-tech Innovation and Sci-tech Finance

    Institute of Scientific and Technical Information of China (English)

    徐玉莲; 王玉冬; 林艳

    2011-01-01

    The coupling coordinated development of sci-tech innovation and sci-tech finance is the important sup- port for regional knowledge economy growth. Based on the definition of sci-tech finance, analyzes the coupling rela- tionship between regional sci-tech innovation and sci-tech finance. The paper constructs the evaluation model of cou- piing coordinated degree, and uses the model to evaluate the coupling coordinated degrees of provincial regions in China. The results show that the coupling coordinated degrees are on the low side, the development of sci-tech fi- nance lags behind sci-tech innovation in most provinces, and the gaps of the coupling coordinated degrees in East Middle West regions are relatively significant. According to the result of evaluation, some policy suggestions to pro- mote the coupling coordinated development of sci-tech innovation and sci-tech finance are put forward. The re- search provides scientific basis and decision reference for the coordinated and sustainable development of regional sci-tech innovation and sci-tech finance.%科技创新与科技金融耦合协调发展对区域知识经济增长具有强有力的支撑作用。通过对科技金融内涵的界定和区域科技创新与科技金融的互动耦合关系分析,构建区域科技创新与科技金融耦合协调度评价模型,并运用我国省级区域统计数据,对其耦合协调度进行实证分析。实证研究结果表明:我国各省市科技创新与科技金融耦合协调度整体偏低;大部分省市科技金融滞后于科技创新发展;东、中、西部地区耦合协调度差距较为显著。据此给出我国区域科技创新与科技金融耦合协调发展的相关政策建议。

  2. Study on the comprehensive advantage evaluation method of high-tech enterprises based on RBF artificial neural network

    Institute of Scientific and Technical Information of China (English)

    WANG Hong-qi; WANG Xue-yuan; TANG Yu

    2005-01-01

    This paper designs an intelligent evaluation approach using a Radial Basis Function (RBF) Artificial Neural Network. We based our approach on establishing a comprehensive advantage evaluating index system that offers scientific substance for creating a development plan and the strategic management of high-tech industry and regional cluslers of high-tech enterprises. Furthermore, this paper selects some typical high-tech enterprises' data to make comprehensive training on the network system. Meanwhile, the paper chooses some enterprises as testing samples to test the method, the result of which proves that this method is truly effective. The research of this paper provides a comprehensive advantage evaluating and managing method for high-tech enterprise.

  3. 菱科电子技术(中国)有限公司%Link Tech (China) Co.,Ltd

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Link Tech Co.,Ltd thought that the quality management should be a “overall” quality management,the emphasis lies in the “comprehensive”, and the point is “market”. We didn't acknowledge that the enter-prise scale has direct relation with management quality. Link Tech would adopted various methods toregister the “Top100 Chinese Electronic Enterprises for Quality” evaluation activity.

  4. Definition of a shortcut methodology for assessing flood-related Na-Tech risk

    Directory of Open Access Journals (Sweden)

    E. Marzo

    2012-11-01

    Full Text Available In this paper a qualitative methodology for the initial assessment of flood-related Na-Tech risk was developed as a screening tool to identify which situations require a much more expensive quantitative risk analysis (QRA. Through the definition of some suitable key hazard indicators (KHIs, the proposed methodology allows the identification of the Na-Tech risk level associated with a given situation; the analytical hierarchy process (AHP was used as a multi-criteria decision tool for the evaluation of such qualitative KHIs. The developed methodology was validated through two case studies by comparing the predicted risk levels with the results of much more detailed QRAs previously presented in literature and then applied to the real flood happened at Spolana a.s., Neratovice, Czech Republic in August 2002.

  5. A Concept of Constructing a Common Information Space for High Tech Programs Using Information Analytical Systems

    Science.gov (United States)

    Zakharova, Alexandra A.; Kolegova, Olga A.; Nekrasova, Maria E.

    2016-04-01

    The paper deals with the issues in program management used for engineering innovative products. The existing project management tools were analyzed. The aim is to develop a decision support system that takes into account the features of program management used for high-tech products: research intensity, a high level of technical risks, unpredictable results due to the impact of various external factors, availability of several implementing agencies. The need for involving experts and using intelligent techniques for information processing is demonstrated. A conceptual model of common information space to support communication between members of the collaboration on high-tech programs has been developed. The structure and objectives of the information analysis system “Geokhod” were formulated with the purpose to implement the conceptual model of common information space in the program “Development and production of new class mining equipment - “Geokhod”.

  6. Childbirth education in rural haiti: reviving low-tech teaching strategies.

    Science.gov (United States)

    Gibson, Martha; Bowles, Betty Carlson; Jansen, Lauren; Leach, Jane

    2013-01-01

    On a medical mission into rural mountainous regions of Haiti, the authors were charged with teaching safer childbirth practices to untrained, mostly illiterate traditional birth attendants (TBA) who spoke Haitian Creole. In this isolated region with no physician or accessible hospital, almost all births occur at home. With no electricity, safe water supply, or sanitation facilities, childbirth education was a challenge. Accustomed to electronic, high-tech teaching aids, these childbirth educators had to modify educational strategies for these extraordinary circumstances. A successful solution was to revive decades-old teaching techniques and visual aids once used in Lamaze classes. The purpose of this article is to describe the teaching environment, the target audience, and the low-tech approach to childbirth education in Haiti.

  7. An Optimized Grey Dynamic Model for Forecasting the Output of High-Tech Industry in China

    Directory of Open Access Journals (Sweden)

    Zheng-Xin Wang

    2014-01-01

    Full Text Available The grey dynamic model by convolution integral with the first-order derivative of the 1-AGO data and n series related, abbreviated as GDMC(1,n, performs well in modelling and forecasting of a grey system. To improve the modelling accuracy of GDMC(1,n, n interpolation coefficients (taken as unknown parameters are introduced into the background values of the n variables. The parameters optimization is formulated as a combinatorial optimization problem and is solved collectively using the particle swarm optimization algorithm. The optimized result has been verified by a case study of the economic output of high-tech industry in China. Comparisons of the obtained modelling results from the optimized GDMC(1,n model with the traditional one demonstrate that the optimal algorithm is a good alternative for parameters optimization of the GDMC(1,n model. The modelling results can assist the government in developing future policies regarding high-tech industry management.

  8. Using a Mixed Model to Evaluate Job Satisfaction in High-Tech Industries.

    Science.gov (United States)

    Tsai, Sang-Bing; Huang, Chih-Yao; Wang, Cheng-Kuang; Chen, Quan; Pan, Jingzhou; Wang, Ge; Wang, Jingan; Chin, Ta-Chia; Chang, Li-Chung

    2016-01-01

    R&D professionals are the impetus behind technological innovation, and their competitiveness and capability drive the growth of a company. However, high-tech industries have a chronic shortage of such indispensable professionals. Accordingly, reducing R&D personnel turnover has become a major human resource management challenge facing innovative companies. This study combined importance-performance analysis (IPA) with the decision-making trial and evaluation laboratory (DEMATEL) method to propose an IPA-DEMATEL model. Establishing this model involved three steps. First, an IPA was conducted to measure the importance of and satisfaction gained from job satisfaction criteria. Second, the DEMATEL method was used to determine the causal relationships of and interactive influence among the criteria. Third, a criteria model was constructed to evaluate job satisfaction of high-tech R&D personnel. On the basis of the findings, managerial suggestions are proposed.

  9. Forming system of strategic innovation management at high-tech engineering enterprises

    Science.gov (United States)

    Ergunova, O. T.; Lizunkov, V. G.; Malushko, E. Yu; Marchuk, V. I.; Ignatenko, A. Yu

    2017-02-01

    The article considers the processes of forming the strategic system of innovative activity management at the enterprises of a high-tech mechanical engineering complex (MEC) that are traditionally decisive in shaping the economic base of Russia. The authors proposed a method of designing a strategic system of innovative activity management at the MEC’s enterprises of the region which is based on the consideration of means and opportunities of the enterprise to implement intellectual activity. The proposed methodology and the empirical results constituted a ground for developing a system of strategic innovation management when performing the state-guaranteed order at the hi-tech MEC enterprises. Its implementation will help to reduce the level of uncertainty throughout the entire life cycle of an innovative activity product.

  10. PRODUCTION RISKS AND ECONOMIC HAZARDS OF MODERN HIGH-TECH INDUSTRIES

    Directory of Open Access Journals (Sweden)

    Khrustalev E. Y.

    2016-03-01

    Full Text Available The article shows that when the plans for the creation and production of modern high-tech innovative products for different purposes it is necessary to consider all possible risks and dangers that accompany modern innovative projects. New approaches to the planning of the development of science-intensive industries should ensure that the accounting and the management of risk situations of the financialeconomic, scientific-technical and industrialtechnological character. One of the promising directions of the domestic output of the industrial complex from its current unstable state is a strategic planning and forecasting of its activity, the development strategies should be based on an evaluation of available enterprise resources, the lack of which leads to stagnation. With active government support the company can successfully implement a strategy of stabilization and progress through cooperation and diversification of production and to make a technological breakthrough in creating high-tech products of new generation

  11. 11TH Annual Science and Engineering Technology Conference/DoD Tech Exposition

    Science.gov (United States)

    2010-04-15

    Technologies, Inc. Mr. John Maguire Georgia Tech Research Institute Mr. Roger Mann Lockheed Martin Corporation Dr. Todd Marek Scientific Research...Pandemic Disease Manmade Disasters Illegal Migration UNCLASSIFIED UNCLASSIFIED 5 60 Organizations are part of our Team!!! Public Safety Canada Transport...Resources (e.g., Illegal Fishing) • Pandemic Disease – HIV/AIDS • Insufficient Means to Confront Challenges •Dependence on Foreign Assistance 11.7

  12. A holistic model for matching high-tech hearing aid features to elderly patients.

    Science.gov (United States)

    Johnson, C E; Danhauer, J L; Krishnamurti, S

    2000-12-01

    Successful hearing aid fittings using high-technology features for elderly patients require consideration of factors beyond results obtained from routine audiologic evaluations. A holistic hearing aid selection, fitting, and evaluation approach that considers patient characteristics from communication, physical, psychological, and social assessment domains is presented here along with a checklist and flowcharts for matching high-tech hearing aid features to older persons who are hearing aid candidates.

  13. W kierunku bazy pełnotekstowej - inicjatywy BazTech

    OpenAIRE

    2009-01-01

    The paper presents the BazTech’s initiatives which lead to transforming the database from a bibliographic one into a full-text one. It points out the co-operation between ICM UW and journal publishers in the field of gaining full-text articles. It also discusses the formal procedures of the co-operation and the rules of proceeding within Konsorcjum BazTech.

  14. From novice to tech savvy teachers. A Report of Faculty Members’ Teaching with Technology Experiences

    Directory of Open Access Journals (Sweden)

    Jennie M. Hwang

    2011-06-01

    Full Text Available This study explores faculty motivations to adopt technologies for their courses, their current uses of technologies and perceptions of teaching with technologies, as well as their suggestions for how their institutions can best support them. In particular, this investigation compares novice and tech savvy teachers by looking at differences in the technologies they use, how they integrate these technologies in their courses, and the challenges they experience in doing so.

  15. Standardization and Innovation The 2nd Shenzhen Hi-tech Standardization Forum Held

    Institute of Scientific and Technical Information of China (English)

    Huang Manxue; Huang Li

    2006-01-01

    @@ "The 2nd Shenzhen Hi-tech Standardization Forum"was fulfilled in Shenzhen Civil Center on November 25th,2005. The forum lasted for two days. There were around 400 delegates from enterprises and standardization organizations participating in this forum. Nine experts from standardization, intellectual property organizations and enterprises made their excellent speeches focusing on the topic "Standardardization and Innovation". All participates agreed that standardization improves innovation efficiently.

  16. BREAKING THROUGH THE "BRICK WALL" — USING AN INTERDISCIPLINARY STRATEGY TO MARKET HIGH-TECH PRODUCTS

    OpenAIRE

    ADAM PERRY TOW; Amit M. Joshi

    2011-01-01

    Marketing high-tech products poses challenges to classically trained marketers who may be unfamiliar with a product's underlying science or technology. Often such marketing teams, lacking scientific backgrounds, find it particularly difficult to interface with R&D and truly understand a product's inner workings — something we show to be critical to fully assessing a product for effective differentiation and marketing. By utilizing a novel marketing strategy, the Interdisciplinary Strategic Ma...

  17. Science and Technology Is Not Simply Equal to Sci-Tech

    Institute of Scientific and Technical Information of China (English)

    Xingmin Li

    2003-01-01

    @@ The terms "science" (Hanyu Pinyin: Kēxué) and"technology" (Jìshù), in western languages, are usu-ally used separately with different meanings or to-gether as "science and technology". However, theyare often mentioned as "Kēxué Jìshù", or even abbre-viated as "sci-tech (Kējì)" in China (It is used in asimilar way in Japan).

  18. A Platform Across the Valley of Death: Tech Transition via Open Enterprise Information System Development

    OpenAIRE

    2014-01-01

    Approved for public release; distribution is unlimted. Achieving “Tech Transfer”, i.e. “an invention usefully adopted,” is difficult, particularly within the Defense Enterprise. The Defense acquisition system is designed to transition technology through a long serial process ill suited for Information Technology (IT). However, there is a successful commercial practice for transitioning IT called “Product Line Architecture” (PLA). PLA optimizes a specified open standard technical framework ...

  19. METHODS OF EVALUATION OF FINANCIAL EFFICIENCY OF HIGH-TECH PROJECTORIENTED COMPANIES

    Directory of Open Access Journals (Sweden)

    Matyushok V. M.

    2015-05-01

    Full Text Available The subject of the research is a complex of high-tech manufacturing companies integrated and functioning in the form of project-oriented companies that are complex dynamic systems with increased efficiency due to changes in its structure and functions, institutional adaptation or use of project management techniques and optimization. The article reveals peculiarities of assessment methods financial performance knowledge-based project-oriented businesses, the main of which is that companies consider their activities as separate independent projects, which have their cost centers and profit. The author's solution to the problem of choosing the optimal investment project among several possible within the framework of the investment program or portfolio of projects, which can be mutually independent of each other, or mutually interdependent. The aim of the work is to study the possibilities and prospects of organizational and economic mechanisms for the use of project campaign for the effective management of knowledge-based enterprises that will quickly adopt new technologies and create optimal production structure. The results will be useful for the public authorities responsible for the development of high-tech industries as well as public and private companies wishing to profitably participate in the implementation of major innovative projects and programs. In the course of the study suggested methods for evaluating the effectiveness of high-tech project-oriented businesses, allowing them to identify the main advantages and disadvantages in meeting their specific production problems

  20. Challenges to achievement of metal sustainability in our high-tech society.

    Science.gov (United States)

    Izatt, Reed M; Izatt, Steven R; Bruening, Ronald L; Izatt, Neil E; Moyer, Bruce A

    2014-04-21

    Achievement of sustainability in metal life cycles from mining of virgin ore to consumer and industrial devices to end-of-life products requires greatly increased recycling rates and improved processing of metals using conventional and green chemistry technologies. Electronic and other high-tech products containing precious, toxic, and specialty metals usually have short lifetimes and low recycling rates. Products containing these metals generally are incinerated, discarded as waste in landfills, or dismantled in informal recycling using crude and environmentally irresponsible procedures. Low recycling rates of metals coupled with increasing demand for high-tech products containing them necessitate increased mining with attendant environmental, health, energy, water, and carbon-footprint consequences. In this tutorial review, challenges to achieving metal sustainability, including projected use of urban mining, in present high-tech society are presented; health, environmental, and economic incentives for various government, industry, and public stakeholders to improve metal sustainability are discussed; a case for technical improvements, including use of molecular recognition, in selective metal separation technology, especially for metal recovery from dilute feed stocks is given; and global consequences of continuing on the present path are examined.