WorldWideScience

Sample records for tech prep participants

  1. Tech Prep and the Rural Context.

    Science.gov (United States)

    Roth, Gene L.

    1996-01-01

    Discusses implementation of tech prep in rural areas and notes that relatively little research has been done on behalf of small town schools. Teachers' comments regarding tech prep implementation provide additional insight into the situation. (JOW)

  2. Planning a Tech Prep Program in Hospitality. Final Report.

    Science.gov (United States)

    Chicago City Colleges, IL. Chicago City-Wide Coll.

    A project conducted to establish tech prep articulation training agreements between City Colleges of Chicago and several public secondary schools is described in this report. Project activities were as follows: (1) developed a handbook to define the tech prep experience and guide committee members on how tech prep can be a valuable asset to…

  3. Prep/Tech: Volume 1, No. 1, Youth on homelessness

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    PREP/TECH is a skill development, academic enrichment program of U. of Toledo in Toledo OH and The Engineers Foundation of Ohio; it addresses the mathematics, science, language, and intellectual needs of about 100 African-American and Hispanic-American 7th, 8th, and 9th graders in Toledo. This summer, after 3 weeks of classes, the 80 students returned for a second 3 week session and were divided into two groups, one studying the growing problem of homelessness in America. This group researched and published a pamphlet on homelessness. This report is divided into: myths, causes, descriptions, and solutions. Finally, a brief account is given of the homelessness project.

  4. How To Implement a Tech Prep Program Based on the Rhode Island Model. Tech Prep Associate Degree Program. Technical Programs. Business/Office Administration Programs. Allied Health/Dental Health Programs.

    Science.gov (United States)

    Community Coll. of Rhode Island, Warwick.

    This implementation guide contains information based on experiences that occurred during the development and implementation of the Rhode Island Tech Prep Model. It is intended to assist educators in addressing challenges and obstacles faced by the program early in the planning process. It begins with a rationale for tech prep. Rhode Island…

  5. Restructuring Student Experiences Using Tech Prep Mapping To Integrate Vocational and Academic Curriculum.

    Science.gov (United States)

    Pirozzoli, Don

    The growing emphasis on accountability and the demand for better prepared students is pressing institutions of higher education to examine restructuring. Student experiences represent an important arena for school restructuring, and a useful approach to changing student experiences is the Tech Prep Mapping (TPM) process. The TPM process requires…

  6. The Boeing Company's Tech Prep Story: A Community College Bridge to the School-to-Work Strategy.

    Science.gov (United States)

    Gayton, Carver; Parnell, Dale

    1996-01-01

    Reviews the Boeing Tech Prep Program, an associate degree program combining high school and community college vocational and academic curricula. Describes the three phases of the program's development: the provision of seed grants to schools, the development of an associate degree program, and the institution of an internship program. (MAB)

  7. The Boeing Company's Tech Prep Story: A Community College Bridge to the School-to-Work Strategy.

    Science.gov (United States)

    Gayton, Carver; Parnell, Dale

    1996-01-01

    Reviews the Boeing Tech Prep Program, an associate degree program combining high school and community college vocational and academic curricula. Describes the three phases of the program's development: the provision of seed grants to schools, the development of an associate degree program, and the institution of an internship program. (MAB)

  8. Lecture to inquiry: The transformation of a tech prep biology teacher

    Science.gov (United States)

    Haskell, Deborah Harris

    As teachers implement the National Science Education Standards (NRC, 1996) many have to reform the instructional methods they have used throughout their careers. This case study examines the transformation of Laurie, a 20-year teacher, during her first year of change from a "traditional" textbook/lecture style of teaching to a facilitator of an inquiry-based classroom. Implementing change requires not only pedagogical expertise, but also the belief that the modifications can be made and that the outcomes are significant. Using Bandura's social cognitive theory as a framework, changes in Laurie's self-efficacy, outcome expectancy, and motivation are followed throughout the transition. During her first year of change, Laurie used worksheets, small group activities, and guided inquiry activities, all strategies in which she had high self-efficacy and experienced positive student outcomes. She rarely used class forums, authentic assessment, and formative assessment. Factors that influenced her change were experiential professional development opportunities that allowed her to practice inquiry-based techniques, a change in her teaching environment from college prep chemistry to tech prep biology, autonomy regarding classroom decisions, and reflective decision making as she learned through experience. Using a standards-based biology textbook increased her self-efficacy toward using inquiry-based practices. The textbook format of embedding text in activities rather than adding activities to the text resulted in an increase of the number and frequency of activities done. Facilitating the textbook's Guided Inquiries and Extended Inquiries helped Laurie gain experience with inquiry-based methods. She also realized that when building from the students' concrete experiences, her students were able to attain higher-level thinking skills. The study revealed six factors contributing to Laurie's change process: (a) experiential professional development, (b) motivation for change

  9. SPC-Prep 1. Participant's Manual. Workplace Education. Project ALERT.

    Science.gov (United States)

    Ruetz, Nancy

    This companion document to the instructor's guide for a course designed to prepare employees for statistical process control (SPC) training given at their workplace by refreshing math skills and building the concepts and vocabulary necessary to understand SPC in manufacturing environments. SPC-Prep 1 addresses the math skills necessary to perform…

  10. High Schools that Work and Tech Prep: Improving Student Performance in Basic Skills.

    Science.gov (United States)

    Flowers, Jim

    2000-01-01

    Test results for 244 agricultural education students in High Schools that Work (HSTW) sites in North Carolina indicated that, compared to all students at HSTW sites and to college-prep students, they failed to meet HSTW goals in math, reading, and science but were making progress. Their math and science performance was higher than other vocational…

  11. Sexual Behavior, Risk Compensation, and HIV Prevention Strategies Among Participants in the San Francisco PrEP Demonstration Project: A Qualitative Analysis of Counseling Notes.

    Science.gov (United States)

    Carlo Hojilla, J; Koester, Kimberly A; Cohen, Stephanie E; Buchbinder, Susan; Ladzekpo, Deawodi; Matheson, Tim; Liu, Albert Y

    2016-07-01

    Pre-exposure prophylaxis (PrEP) is a viable HIV prevention strategy but risk compensation could undermine potential benefits. There are limited data that examine this phenomenon outside of clinical trials. We conducted a qualitative analysis of counseling notes from the San Francisco site of the US PrEP demonstration project to assess how men who have sex with men used PrEP as a prevention strategy and its impact on their sexual practices. Four major themes emerged from our analysis of 130 distinct notes associated with 26 participants. Prevention strategy decision-making was dynamic, often influenced by the context and perceived risk of a sexual encounter. Counselors noted that participants used PrEP in conjunction with other health promotion strategies like condoms, asking about HIV status of their sex partners, and seroadaptation. With few exceptions, existing risk reduction strategies were not abandoned upon initiation of PrEP. Risk-taking behavior was 'seasonal' and fluctuations were influenced by various personal, psychosocial, and health-related factors. PrEP also helped relieve anxiety regarding sex and HIV, particularly among serodiscordant partners. Understanding sexual decision-making and how PrEP is incorporated into existing prevention strategies can help inform future PrEP implementation efforts.

  12. How Bioethics is Complementing Human Rights in Realizing Health Access for Clinical Trial Participants: The Case of Formative PrEP Access in South Africa.

    Science.gov (United States)

    Singh, Jerome

    2015-06-11

    Following the demise of apartheid, human rights in South Africa are now constitutionally enshrined.The right to health in South Africa's Constitution has been credited with transforming the lives of millions of people by triggering programmatic reforms in HIV treatment and the prevention of mother to child transmission (MTCT) of HIV.However, a constitutionally enshrined right to health offers no guarantee that clinical trial participants will enjoy post-trial access to beneficial interventions. Using access to HIV pre-exposure prophylaxis (PrEP) in South Africa as an example, this paper argues that adherence to bioethics norms could realize the right to health for trial participants following the end of a clinical trial.

  13. ACT Verbal Prep Course

    CERN Document Server

    Standridge, Nathan

    2012-01-01

    Comprehensive Prep for ACT Verbal. Every year, students pay 1,000 and more to test prep companies to prepare for the verbal sections of the ACT. Now you can get the same preparation in a book. The verbal sections are not easy. There is no quick fix that will allow you to "beat" the ACT, but it is very learnable. If you study hard and master the techniques in this book, your score will improve-significantly. The ACT cannot be "beaten." But it can be mastered-through hard work, analytical thought, and by training yourself to think like a test writer. Many of the exercises in this book are design

  14. SAT math prep course

    CERN Document Server

    Kolby, Jeff

    2011-01-01

    Comprehensive Prep for SAT Math Every year, students pay 1,000 and more to test prep companies to prepare for the math section of the new SAT. Now you can get the same preparation in a book. Features: * Comprehensive Review: Twenty-three chapters provide complete review of SAT math. * Practice: Includes 164 examples and more than 500 exercises! Arranged from easy to medium to hard to very hard. * Diagnostic Test: The diagnostic test measures your strengths and weaknesses and directs you to areas you need to study more. * Performance: If your target is a 700+ score, this is the book!

  15. New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA

    Science.gov (United States)

    Zucchelli, Chiara; Ferrari, Elena; Blasi, Francesco; Musco, Giovanna; Bruckmann, Chiara

    2017-01-01

    PREP1 and PBX1 are homeodomain (HD) transcription factors that play crucial roles in embryonic development. Here, we present the first biophysical characterization of a PREP1 HD, and the NMR spectroscopic study of its DNA binding pocket. The data show that residues flanking the HD participate in DNA binding. The kinetic parameters for DNA binding of individual PREP1 and PBX1 HDs, and of their combination, show that isolated PREP1 and PBX1 HDs bind to DNA in a cooperative manner. A novel PREP1 motif, flanking the HD at the C-terminus, is required for cooperativity. PMID:28094776

  16. PMP exam prep

    CERN Document Server

    Mulcahy, Rita

    2013-01-01

    This book has been FULLY updated to reflect PMI's changes to the PMP exam, and should be used to prepare for all PMP exams delivered on or after July 30th of 2013. Can you imagine valuing a book so much that you send the author a Thank You letter? Hundreds of thousands of project managers know and understand why PMP Exam Prep is a worldwide best-seller. Years of PMP exam preparation experience, endless hours of ongoing research, interviews with project managers who failed the exam to identify gaps in their knowledge, and a razor-sharp focus on making sure project managers don't waste a single minute of their time studying are THE reasons this book is the best-selling PMP exam preparation guide in the world. PMP Exam Prep, Eighth Edition contains hundreds of updates and improvements from previous editions--including new exercises and sample questions never before in print. Offering hundreds of sample questions, critical time-saving tips plus games and activities available nowhere else, this book will help y...

  17. Social, structural, behavioral and clinical factors influencing retention in Pre-Exposure Prophylaxis (PrEP) care in Mississippi

    Science.gov (United States)

    Arnold, Trisha; Brinkley-Rubinstein, Lauren; Chan, Philip A.; Perez-Brumer, Amaya; Bologna, Estefany S.; Beauchamps, Laura; Johnson, Kendra; Mena, Leandro; Nunn, Amy

    2017-01-01

    Pre-exposure prophylaxis (PrEP) is a biomedical intervention that can reduce rates of HIV transmission when taken once daily by HIV-negative individuals. Little is understood about PrEP uptake and retention in care among the populations most heavily impacted by the HIV epidemic, particularly among young men who have sex with men (YMSM) in the Deep South. Therefore, this study explored the structural, social, behavioral, and clinical factors that affect PrEP use and retention in care among YMSM in Jackson, Mississippi. Thirty MSM who were prescribed PrEP at an outpatient primary care clinic were interviewed and included 23 men who had been retained in PrEP care and seven who had not been retained. The mean age of participants was 26.6 years. Most (23) participants were African American. Major factors affecting PrEP use and retention in PrEP care included 1) structural factors such as cost and access to financial assistance for medications and clinical services; 2) social factors such as stigma and relationship status; 3) behavioral factors including sexual risk behaviors; and 4) clinical factors such as perceived and actual side effects. Many participants also discussed the positive spillover effects of PrEP use and reported that PrEP had a positive impact on their health. Four of the seven individuals who had not been retained re-enrolled in PrEP care after completing their interviews, suggesting that case management and ongoing outreach can enhance retention in PrEP care. Interventions to enhance retention in PrEP care among MSM in the Deep South will be most effective if they address the complex structural, social, clinical, and behavioral factors that influence PrEP uptake and retention in PrEP care. PMID:28222118

  18. Mentoring clinical ladder advancement with a facilitated prep class.

    Science.gov (United States)

    Winslow, Susan A; Blankenship, Jean

    2007-01-01

    The authors describe a strategy for encouraging participation and overcoming reluctance of staff to participate in an optional professional advancement career ladder program. A facilitated prep class in a computer skills laboratory provides nurses with the framework for completing application requirements in a casual, supportive atmosphere.

  19. PREP advertisement features affect smokers' beliefs regarding potential harm.

    Science.gov (United States)

    Strasser, A A; Tang, K Z; Tuller, M D; Cappella, J N

    2008-09-01

    The Institute of Medicine report on potential reduced exposure products (PREPs) recommends that advertising and labelling be regulated to prevent explicitly or implicitly false or misleading claims. Belief that a product is less harmful may increase use or prevent smoking cessation. To determine the effect of altering advertisement features on smokers' beliefs of the harm exposure from a PREP. A Quest advertisement was digitally altered using computer software and presented to participants using web-based television recruitment contracted through a survey company. 500 current smokers completed demographic and smoking history questions, were randomised to view one of three advertisement conditions, then completed eight items assessing their beliefs of the harmfulness of the product. Advertisement conditions included the original, unaltered advertisement; a "red" condition where the cigarette packages were digitally altered to the colour red, implying increased harm potential; and a "no text" condition where all text was removed to reduce explicit product information. Polytomous logistic regression, using "incorrect," "unsure" and "correct" as outcomes, and advertisement type and covariates as predictors, was used for analyses. Participants randomised to the "no text" advertisement were less likely to be incorrect in their beliefs that Quest cigarettes are lower in tar, less addictive, less likely to cause cancer, have fewer chemicals, are healthier and make smoking safer. Smokers can form false beliefs about the harmfulness of PREP products based on how the PREPs are marketed. Careful examination must be undertaken to provide empirical evidence to better formulate regulatory principles of PREP advertising.

  20. Knowledge is Power! Increased Provider Knowledge Scores Regarding Pre-exposure Prophylaxis (PrEP) are Associated with Higher Rates of PrEP Prescription and Future Intent to Prescribe PrEP.

    Science.gov (United States)

    Blumenthal, Jill; Jain, Sonia; Krakower, Douglas; Sun, Xiaoying; Young, Jason; Mayer, Kenneth; Haubrich, Richard

    2015-05-01

    The FDA approval of emtricitabine/tenofovir disoproxil fumarate for pre-exposure prophylaxis (PrEP) in 2012 has raised questions about the delivery of PrEP in a real-world setting. iPad-based questionnaires were given to providers at conferences in California and New York to assess knowledge, experience and attitudes regarding PrEP in HIV and non-HIV providers. HIV provider status was defined either by self-identification or by having greater than 5 years of HIV care experience. Knowledge scores were the sum of correct answers from five PrEP knowledge questions. Univariate analyses used t-test to compare knowledge scores and Fisher's exact test for past or future PrEP prescription between HIV and non-HIV providers. Multivariable linear or logistic regression models were used to assess factors associated with the outcomes. Of 233 respondents, the mean age was 40 years, 59 % were White, 59 % were physicians and 52 % were HIV providers. In univariate analysis, mean PrEP knowledge scores (max 5) were significantly higher for HIV providers (2.8 versus 2.2; p 41 (mean 2.8 versus 2.3; p = 0.004), White race (2.7 versus 2.2; p = 0.026) and participants in the New York region (3.0 versus 2.3; p knowledge scores, all but age remained significant. Among 201 potential prescribers, the rate of prior PrEP prescription was higher among HIV providers than non-HIV providers (34 versus 9 %; p knowledge score, but the association with provider status was no longer significant in multivariable analysis that controlled for knowledge. Intent to prescribe PrEP in the future was high for all provider types (64 %) and was associated with knowledge scores in multivariable analysis. The most common concerns about PrEP (>40 % of providers) were drug toxicities, development of resistance and patient adherence to follow-up; 32 % identified risk compensation as a concern. HIV providers had significantly greater PrEP knowledge than non-HIV providers, but differences by provider type in past PrEP

  1. High Tech

    OpenAIRE

    Manterola, Javier; Fernández Casado, S.A., Carlos

    1987-01-01

    "High Tech" is an architectural movement that emphasizes the technological dimension of the building as expression means. Its research includes the diverse structures composing the building: resistance, closing, services, distribution and communications. Its results are unequal since not all the buildings rising from this movement are high technology and already are other buildings not enrolled in this movement. Renzo Piano, Richard Rogers and Norman Foster are its main representatives.

  2. High Tech

    Directory of Open Access Journals (Sweden)

    Manterola, Javier

    1987-02-01

    Full Text Available "High Tech" is an architectural movement that emphasizes the technological dimension of the building as expression means. Its research includes the diverse structures composing the building: resistance, closing, services, distribution and communications. Its results are unequal since not all the buildings rising from this movement are high technology and already are other buildings not enrolled in this movement. Renzo Piano, Richard Rogers and Norman Foster are its main representatives.

    "High Tech" es un movimiento arquitectónico que enfatiza la dimensión tecnológica del edificio como medio de expresión. Su investigación se fija en las diversas estructuras que configuran el edificio, la resistente, la de cerramiento, la de servicios, la de distribución y comunicaciones. Sus resultados son desiguales pues no todos los edificios que surgen de este movimiento son alta tecnología y muchos otros no inscritos en dicho movimiento sí lo son. Renzo Piano, Richard Rogers y Norman Foster son sus representantes más destacados.

  3. I Knew I Would Be Safer. Experiences of Kenyan HIV Serodiscordant Couples Soon After Pre-Exposure Prophylaxis (PrEP) Initiation.

    Science.gov (United States)

    Ngure, Kenneth; Heffron, Renee; Curran, Kathyrn; Vusha, Sophie; Ngutu, Mariah; Mugo, Nelly; Celum, Connie; Baeten, Jared M

    2016-02-01

    Pre-exposure prophylaxis (PrEP) for HIV-uninfected persons is highly efficacious for HIV prevention. Understanding how people at risk for HIV will use PrEP is important to inform PrEP scale-up and implementation. We used qualitative methods to gather insights into couples' early experiences with PrEP use within the Partners Demonstration Project, an open-label implementation study evaluating integrated delivery of PrEP and antiretroviral therapy (ART). PrEP is offered to HIV uninfected partners until the HIV-infected partner initiates and sustains ART use (i.e., PrEP as a "bridge" to ART initiation and viral suppression). From August 2013 to March 2014 we conducted 20 in-depth dyadic interviews (n = 40) with heterosexual HIV serodiscordant couples participating at the Thika, Kenya study site, exploring how couples make decisions about using PrEP for HIV prevention. We developed and applied deductive and inductive codes to identify key themes related to experiences of PrEP initiation and use of time-limited PrEP. Couples reported that PrEP offered them an additional strategy to reduce the risk of HIV transmission, meet their fertility desires, and cope with HIV serodiscordance. Remaining HIV negative at follow-up visits reinforced couples' decisions and motivated continued adherence to PrEP. In addition, confidence in their provider's advice and client-friendly services were critical to their decisions to initiate and continue use of PrEP. Strategies for wide-scale PrEP delivery for HIV serodiscordant couples in low resource settings may include building capacity of health providers to counsel on PrEP adoption while addressing couples' concerns and barriers to adoption and continued use.

  4. PREP advertisement features affect smokers’ beliefs regarding potential harm

    Science.gov (United States)

    Strasser, Andrew A; Tang, Kathy Z; Tuller, Michael D; Cappella, Joseph N

    2014-01-01

    Background The Institute of Medicine report on potential reduced exposure products (PREPs) recommends that advertising and labelling be regulated to prevent explicitly or implicitly false or misleading claims. Belief that a product is less harmful may increase use or prevent smoking cessation. Objective To determine the effect of altering advertisement features on smokers’ beliefs of the harm exposure from a PREP. Methods A Quest advertisement was digitally altered using computer software and presented to participants using web-based television recruitment contracted through a survey company. 500 current smokers completed demographic and smoking history questions, were randomised to view one of three advertisement conditions, then completed eight items assessing their beliefs of the harmfulness of the product. Advertisement conditions included the original, unaltered advertisement; a “red” condition where the cigarette packages were digitally altered to the colour red, implying increased harm potential; and a “no text” condition where all text was removed to reduce explicit product information. Polytomous logistic regression, using “incorrect,” “unsure” and “correct” as outcomes, and advertisement type and covariates as predictors, was used for analyses. Results Participants randomised to the “no text” advertisement were less likely to be incorrect in their beliefs that Quest cigarettes are lower in tar, less addictive, less likely to cause cancer, have fewer chemicals, healthier and make smoking safer. Conclusions Smokers can form false beliefs about the harmfulness of PREP products based on how the PREPs are marketed. Careful examination must be undertaken to provide empirical evidence to better formulate regulatory principles of PREP advertising. PMID:18768457

  5. Measuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users.

    Science.gov (United States)

    Shrestha, Roman; Karki, Pramila; Altice, Frederick L; Dubov, Oleksandr; Fraenkel, Liana; Huedo-Medina, Tania; Copenhaver, Michael

    2017-07-10

    Although people who use drugs (PWUD) are one of the key risk populations who could benefit from the use of pre-exposure prophylaxis (PrEP), to date, little attention has been given to incorporating PrEP into HIV prevention approaches targeting this underserved group. This study investigated the acceptability of PrEP based on a number of known PrEP attributes among high-risk PWUD in a drug treatment setting. A total of 400 HIV-negative PWUD, who reported drug- and/or sex-related risk behaviors were recruited from a methadone clinic to complete a stated preference (full-profile conjoint) survey. Participants ranked the eight hypothetical PrEP program scenarios with varied combinations of six attributes related to PrEP (cost, dosing, efficacy, side-effects, treatment setting, and frequency of HIV testing). SPSS conjoint procedure was used to estimate the relative importance of each attribute and preferences across eight possible PrEP delivery programs. PrEP acceptability ranged from 30.6 to 86.3% with a mean acceptability of 56.2% across the eight hypothetical PrEP program scenarios. The PrEP program scenario with the highest acceptability had the following attribute levels: insurance covered, daily dosing, 95% effective, no side-effects, treatment at HIV clinic, and HIV testing needed every 6 months. The cost associated with PrEP was the most important attribute (relative importance score: RIS = 38.8), followed by efficacy (RIS = 20.5) and side effects (RIS = 11.9); other attributes had no significant effect. Our findings reported a high acceptability of PrEP in response to different PrEP program scenarios with different attribute profiles. As the result of having this information, researchers and policymakers will be better equipped for evidence informed targeting and dissemination efforts to optimize PrEP uptake among this underserved population.

  6. "Support Your Client at the Space That They're in": HIV Pre-Exposure Prophylaxis (PrEP) Prescribers' Perspectives on PrEP-Related Risk Compensation.

    Science.gov (United States)

    Calabrese, Sarah K; Magnus, Manya; Mayer, Kenneth H; Krakower, Douglas S; Eldahan, Adam I; Hawkins, Lauren A Gaston; Underhill, Kristen; Hansen, Nathan B; Kershaw, Trace S; Betancourt, Joseph R; Dovidio, John F

    2017-04-01

    Despite the demonstrated effectiveness of HIV pre-exposure prophylaxis (PrEP) and evidence that most PrEP users do not engage in risk compensation (i.e., increased risk behavior due to a perceived decrease in HIV susceptibility), some healthcare providers report patient risk compensation to be a deterrent to prescribing PrEP. Overcoming this barrier is essential to supporting PrEP access and uptake among people at risk for HIV. To inform such efforts, this qualitative study explored PrEP-related risk compensation attitudes among providers with firsthand experience prescribing PrEP. US-based PrEP providers (n = 18), most of whom were HIV specialists, were recruited through direct outreach and referral from colleagues and other participants. Individual 90-min semistructured interviews were conducted by phone or in person from September 2014 through February 2015, transcribed, and thematically analyzed. Three attitudinal themes emerged: (1) providers' role is to support patients in making informed decisions, (2) risk behavior while taking PrEP does not fully offset PrEP's protective benefit (i.e., PrEP confers net protection, even with added behavioral risk), and (3) PrEP-related risk compensation is unduly stigmatized within and beyond the healthcare community. Participants were critical of other healthcare providers' negative judgment of patients and reluctance to prescribe PrEP due to anticipated risk compensation. Several providers also acknowledged an evolution in their thinking from initial ambivalence toward greater acceptance of PrEP and PrEP-related behavior change. PrEP providers' insights about risk compensation may help to address unsubstantiated concerns about PrEP-related risk compensation and challenge the acceptability of withholding PrEP on these grounds.

  7. Tech transfer outreach

    Energy Technology Data Exchange (ETDEWEB)

    Liebetrau, S. (ed.)

    1992-01-01

    This document provides an informal summary of the conference workshop sessions. Tech Transfer Outreach '' was originally designed as an opportunity for national laboratory communications and technology transfer staff to become better acquainted and to discuss matters of mutual interest. When DOE field office personnel asked if they could attend, and then when one of our keynote speakers became a participant in the discussions, the actual event grew in importance. The conference participants--the laboratories and DOE representatives from across the nation--worked to brainstorm ideas. Their objective: identify ways to cooperate for effective (and cost-effective) technology transfer outreach. Thus, this proceedings is truly a product of ten national laboratories and DOE, working together. It candidly presents the discussion of issues and the ideas generated by each working group. The issues and recommendations are a consensus of their views.

  8. Framing HIV Pre-Exposure Prophylaxis (PrEP) for the General Public: How Inclusive Messaging May Prevent Prejudice from Diminishing Public Support.

    Science.gov (United States)

    Calabrese, Sarah K; Underhill, Kristen; Earnshaw, Valerie A; Hansen, Nathan B; Kershaw, Trace S; Magnus, Manya; Krakower, Douglas S; Mayer, Kenneth H; Betancourt, Joseph R; Dovidio, John F

    2016-07-01

    Strategic framing of public messages about HIV pre-exposure prophylaxis (PrEP) may influence public support for policies and programs affecting access. This survey study examined how public attitudes toward PrEP differed based on the social group PrEP was described as benefiting ("beneficiary") and the moderating effect of prejudice. Members of the general public (n = 154) recruited online were randomly assigned to three beneficiary conditions: general population, gay men, or Black gay men. All participants received identical PrEP background information before completing measures of PrEP attitudes (specifying beneficiary), racism, and heterosexism. Despite anticipating greater PrEP adherence among gay men and Black gay men and perceiving PrEP as especially beneficial to the latter, participants expressed lower support for policies/programs making PrEP affordable for these groups vs. the general population. This disparity in support was stronger among participants reporting greater prejudice. Inclusive framing of PrEP in public discourse may prevent prejudice from undermining implementation efforts.

  9. Views of policymakers, healthcare workers and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study.

    Science.gov (United States)

    Wheelock, Ana; Eisingerich, Andreas B; Gomez, Gabriela B; Gray, Emily; Dybul, Mark R; Piot, Peter

    2012-01-01

    To examine policymakers and providers' views on pre-exposure prophylaxis (PrEP) and their willingness to support its introduction, to inform policy and practice in this emerging field. Semistructured qualitative interview study. Peru, Ukraine, India, Kenya, Uganda, Botswana and South Africa. 35 policymakers, 35 healthcare workers and 21 non-governmental organisation representatives involved in HIV prevention. Six themes emerged from the data: (1) perceived HIV prevention landscape: prevention initiatives needed to be improved and expanded; (2) PrEP awareness: 50 of 91 participants had heard of PrEP; (3) benefits of PrEP: one component of the combination prevention arsenal that could help prioritise HIV prevention, empower key populations and result in economic gains; (4) challenges of PrEP: regimen complexity, cost and cost-effectiveness, risk compensation, efficacy and effectiveness, stigmatisation and criminalisation, information and training and healthcare system capacity; (5) programmatic considerations: user eligibility, communication strategy, cost, distribution, medication and HIV testing compliance and (6) early versus late implementation: participants were divided as to whether they would support an early introduction of PrEP in their country or would prefer to wait until it has been successfully implemented in other countries, with around half of those we spoke to supporting each option. Very few said they would not support PrEP at all. Despite the multiple challenges identified, there was general willingness to support the introduction of PrEP. Yet, strengthening existing HIV prevention efforts was also deemed necessary. Our results suggest that an effective PrEP programme would be delivered in healthcare facilities and involve non-governmental organisations and the community and consider the needs of mobile populations. Comprehensive information packages and training for users and providers would be critical. The cost of PrEP would be affordable and

  10. Automated screening versus manual screening: a comparison of the ThinPrep imaging system and manual screening in a time study

    DEFF Research Database (Denmark)

    Schledermann, Doris; Hyldebrandt, Tina; Ejersbo, Dorthe;

    2007-01-01

    The ThinPrep Imaging System (TIS) is an automated system that assists cytotechnologists in the primary screening of ThinPrep liquid based cervical samples. Between June 1, 2004, and April 1, 2005, four experienced cytotechnologists participated in the study in which the duration of the screening ...

  11. PrEP: controversy, agency and ownership

    National Research Council Canada - National Science Library

    Cairns, Gus P; Race, Kane; Goicochea, Pedro

    2016-01-01

    Pre‐exposure prophylaxis (PrEP) has been and continues to be an intervention that causes controversy and debate between stakeholders involved in providing or advocating for it, and within communities in need...

  12. Pre-Exposure Prophylaxis (PrEP)

    Science.gov (United States)

    ... Sites Podcasts QR Codes RSS Feeds Social Bookmarking Social Network Sites Text Messaging Twitter Video Games Video Sharing ... PrEP be considered for people who are HIV-negative and at very high risk for HIV infection . ...

  13. PrEP: controversy, agency and ownership

    OpenAIRE

    Cairns, Gus P; Kane Race; Pedro Goicochea

    2016-01-01

    Pre-exposure prophylaxis (PrEP) has been and continues to be an intervention that causes controversy and debate between stakeholders involved in providing or advocating for it, and within communities in need of it. These controversies extend beyond the intrinsically complex issues of making it available. In this commentary, some of the possible roots of the air of dissent and drama that accompanies PrEP are explored. The similarities between the controversies that dogged the earliest human tr...

  14. Acceptability of HIV Pre-Exposure Prophylaxis (PrEP) and Implementation Challenges Among Men Who Have Sex with Men in India: A Qualitative Investigation.

    Science.gov (United States)

    Chakrapani, Venkatesan; Newman, Peter A; Shunmugam, Murali; Mengle, Shruta; Varghese, Jarvis; Nelson, Ruban; Bharat, Shalini

    2015-10-01

    This qualitative study explored the acceptability of HIV pre-exposure prophylaxis (PrEP) among MSM in India, and identified facilitators and barriers to future PrEP uptake. In 2014, we conducted 10 focus groups (n=61) among a purposive sample of diverse MSM recruited through community-based organizations in Chennai and Mumbai, and 10 key informant interviews with community leaders and health care providers. Participants' mean age was 26.1 years (SD 4.8); 62% completed secondary education, and 42% engaged in sex work. No focus group participants had heard of PrEP, but once explained, most reported they would likely use it. PrEP was alternately perceived as a 'back-up plan', a condom substitute, or a burden with concurrent condom use. Facilitators were potential for covert use, sex without condoms, and anxiety-less sex. Potential barriers emerged around stigma associated with PrEP use, fear of disclosures to one's family, wife, or male steady partner, and being labeled as HIV-positive or promiscuous by peers. Preferences emerged for intermittent rather than daily PrEP use, injectable PrEP, and free or subsidized access through community organizations or government hospitals. Key informants expressed additional concerns about risk compensation, non-adherence, and impact on ART availability for treatment. Demonstration projects are needed in India to support PrEP implementation tailored for at-risk MSM. Educational interventions for MSM should address concerns about PrEP effectiveness, side effects, and mitigate risk compensation. Community engagement may facilitate broad acceptability and challenge stigma around PrEP use. Importantly, provision of free or subsidized PrEP is necessary to making implementation feasible among low socioeconomic status MSM in India.

  15. Role of the pharmacist in pre-exposure chemoprophylaxis (PrEP) therapy for HIV prevention.

    Science.gov (United States)

    Clauson, Kevin A; Polen, Hyla H; Joseph, Shine A; Zapantis, Antonia

    2009-01-01

    With a global estimate of 2.5 million new infections of HIV occurring yearly, discovering novel methods to help stem the spread of the virus is critical. The use of antiretroviral chemoprophylaxis for preventing HIV after accidental or occupational exposure and in maternal to fetal transmission has become a widely accepted method to combat HIV. Based on this success, pre-exposure chemoprophylaxis (PrEP) is being explored in at-risk patient populations such as injecting drug users, female sex workers and men who have sex with men. This off-label and unmonitored use has created a need for education and intervention by pharmacists and other healthcare professionals. Pharmacists should educate themselves on PrEP and be prepared to counsel patients about their means of obtaining it (e.g. borrowing or sharing medications and ordering from disreputable Internet pharmacies). They should also be proactive about medication therapy management in these patients due to clinically important drug interactions with PrEP medications. Only one trial exploring the safety and efficacy of tenofovir as PrEP has been completed thus far. However, five ongoing trials are in various stages and two additional studies are scheduled for the near future. Unfortunately, studies in this arena have met with many challenges that have threatened to derail progress. Ethical controversy surrounding post-trial care of participants who seroconvert during studies, as well as concerns over emerging viral resistance and logistical site problems, have already halted several PrEP trials. Information about these early trials has already filtered down to affected individuals who are experimenting with this unproven therapy as an "evening before pill". The potential for PrEP is promising; however, more extensive trials are necessary to establish its safety and efficacy. Pharmacists are well-positioned to play a key role in helping patients make choices about PrEP, managing their therapy, and developing policy

  16. Participation

    African Journals Online (AJOL)

    chifaou.amzat

    2011-08-02

    Aug 2, 2011 ... there is still little theorising about those on the other side of the policy equation. ... The concept of participation designates human beings – their priorities, knowledge .... Thus, a person's mode of participation in the enterprise.

  17. Design Tech High School: d.tech

    Science.gov (United States)

    EDUCAUSE, 2015

    2015-01-01

    A Bay Area charter high school, d.tech develops "innovation-ready" students by combining content knowledge with the design thinking process while fostering a sense of autonomy and purpose. The academic model is grounded in self-paced learning through a flex schedule, high standards, and design thinking through a four-year design…

  18. Acceptability of PrEP among HIV negative Portuguese men who have sex with men that attended 2014 Lisbon pride fair

    Directory of Open Access Journals (Sweden)

    Luís Miguel Rocha

    2014-11-01

    Full Text Available Introduction: Consistent use of PrEP reduces HIV transmission from sexual practices amongst men who have sex with men (MSM up to 92% [1]. Lisbon MSM cohort study estimates point that 59.3% of their participants at entrance (1593 HIV negative MSM enrolled between April 2011 and May 2013 were eligible for PrEP [2], according to the 2014 USA PrEP guidelines [3]. Studies about PrEP acceptability and implementation support policies aimed at increasing and rolling out its use. Hence, the exploratory study about PrEP acceptability in MSM at Lisbon. Materials and Methods: A street-based intercept survey, adapted from Mantell et al. study [4], was the one used on MSM attending the 2014 Lisbon pride fair. The survey included socio-demographic data, PrEP awareness and readiness to use it, probability of MSM's social network to also use it, promptness to join PrEP-related studies, type of PrEP warranted and condomless anal sex practice in the last six months. Results: A total of 110 HIV negative Portuguese MSM responded, with a median age of 33% and 84% of them identified themselves as gay. A majority of MSM were unaware of PrEP (59%; those that were aware, had heard of it trough CheckpointLx (31%, internet (22% or health professionals (20%. 66% were likely or very likely to participate in PrEP-related studies. 57% of MSM were likely or very likely to use PrEP if available and reported that some, if not almost all of their social network, will do it too (70%. Type of PrEP preferred was oral, a pill a day (43%, followed by oral, intermittent intake (32%. Overall 41% of MSM had condomless anal sex practice in the last six months. Conclusions: In this MSM Portuguese sample, a general willingness to adopt PrEP was predominant, specially the oral daily intake. Forty-one percent of participants had had condomless anal sex practice in the last six months and therefore fitted within the criteria to be on Pre-Exposure Prophylaxis (PrEP, according to MSM Risk Index

  19. Acceptability of PrEP among HIV negative Portuguese men who have sex with men that attended 2014 Lisbon pride fair

    Science.gov (United States)

    Miguel Rocha, Luís; José Campos, Maria; Brito, João; Fuertes, Ricardo; Rojas, Jesus; Pinto, Nuno; Mendão, Luís; Esteves, Julio

    2014-01-01

    Introduction Consistent use of PrEP reduces HIV transmission from sexual practices amongst men who have sex with men (MSM) up to 92% [1]. Lisbon MSM cohort study estimates point that 59.3% of their participants at entrance (1593 HIV negative MSM enrolled between April 2011 and May 2013) were eligible for PrEP [2], according to the 2014 USA PrEP guidelines [3]. Studies about PrEP acceptability and implementation support policies aimed at increasing and rolling out its use. Hence, the exploratory study about PrEP acceptability in MSM at Lisbon. Materials and Methods A street-based intercept survey, adapted from Mantell et al. study [4], was the one used on MSM attending the 2014 Lisbon pride fair. The survey included socio-demographic data, PrEP awareness and readiness to use it, probability of MSM's social network to also use it, promptness to join PrEP-related studies, type of PrEP warranted and condomless anal sex practice in the last six months. Results A total of 110 HIV negative Portuguese MSM responded, with a median age of 33% and 84% of them identified themselves as gay. A majority of MSM were unaware of PrEP (59%); those that were aware, had heard of it trough CheckpointLx (31%), internet (22%) or health professionals (20%). 66% were likely or very likely to participate in PrEP-related studies. 57% of MSM were likely or very likely to use PrEP if available and reported that some, if not almost all of their social network, will do it too (70%). Type of PrEP preferred was oral, a pill a day (43%), followed by oral, intermittent intake (32%). Overall 41% of MSM had condomless anal sex practice in the last six months. Conclusions In this MSM Portuguese sample, a general willingness to adopt PrEP was predominant, specially the oral daily intake. Forty-one percent of participants had had condomless anal sex practice in the last six months and therefore fitted within the criteria to be on Pre-Exposure Prophylaxis (PrEP), according to MSM Risk Index in 2014 USA PrEP

  20. Summer Professional Development in Chemistry for Inservice Teachers Using OWL Quick Prep

    Science.gov (United States)

    Powell, Cynthia B.; Pamplin, Kim L.; Blake, Robert E.; Mason, Diana S.

    2010-01-01

    Secondary teachers participating in summer professional development chemistry workshops in Texas used an online chemistry tutoring program, OWL Quick Prep (Day et al. in OWL: Online Web-based Learning, Brooks-Cole Cengage Learning, Florence, KY, 1997) as a part of the inservice training. Self-reported demographic data were used to identify factors…

  1. PrEP (Pre-Exposure Prophylaxis) 101

    Science.gov (United States)

    ... than 70%. Your risk of getting HIV from sex can be even lower if you combine PrEP with condoms and other prevention methods. Expand All Collapse All Video Introductions to PrEP What is PrEP? A Brief ...

  2. High-Tech Architecture

    Directory of Open Access Journals (Sweden)

    Özlem Eşsiz

    1999-05-01

    Full Text Available The technological development in building and construction area, bring with the new construction systems and the new products. The aim of this study is to define the High Tech concept, and set the common and basic characteristics of High Tech applications. During 1970’s High Tech was born and developed in Britain. Especially British Architects Richard Rogers, Michael Hopkins, Norman Foster, Nicholas Grimshaw and Ian Ritchie are the leaders of this style. Their architecture show the machine aesthetic and use of industrial revoluation materials such as glass and steel. The reasons for wide usage of this technology in building constructions are; the ease of renewing the structural and installation systems by the changing technology and giving monumentality to the prestige buildings. High Tech building which we have many examples of give their occupants a lot of opportunities and also they can adapt itself to the time.

  3. HI-TECH OLYMPICS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The only Chinese company in The Olympic Partner Program, Lenovo supplies hi-tech in return for worldwide rights to Olympic logos Nineteen eighty-four was a lucky year for China as the country resumed its seat on the

  4. Are Thai MSM willing to take PrEP for HIV prevention? An analysis of attitudes, preferences and acceptance.

    Directory of Open Access Journals (Sweden)

    Ana Wheelock

    Full Text Available OBJECTIVE: We aimed to understand the attitudes, preferences and acceptance of oral and parenteral PrEP among men who have sex with men (MSM in Thailand. BACKGROUND: Pre-exposure prophylaxis (PrEP, the use of antiretrovirals to prevent HIV acquisition, has shown promising results in recent trials. To assess the potential impact of this new HIV prevention method, in addition to efficacy data, we need to understand which psychosocial factors are likely to determine its uptake among members of potential user groups. METHODS AND FINDINGS: Surveys of willingness to use PrEP products were administered to MSM. Spearman's rank tests were used to uncover associations between questionnaire items. Mann-Whitney tests were performed to ascertain differences between groups. Conjoint analysis was used to examine the attitudes and preferences of MSM towards PrEP attributes. Most participants were willing to consider taking PrEP (39.2% "yes, definitely" and 49.2% "yes, probably" and perceived PrEP as giving them new possibilities in their lives (38.5% "a lot of hope" and 55.8% "some hope", even after being instructed of potential side effects and costs. HIV testing was considered the most important attribute and a daily pill and longer lasting injection in the arm were the preferred routes of administration. CONCLUSIONS: Despite its multiple challenges, MSM in Thailand would be willing to take PrEP, even if they had to experience inconvenience and expense. If PrEP were to be implemented in Thailand, our findings show that its uptake could be considerable.

  5. Values and Preferences on the Use of Oral Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among Multiple Populations: A Systematic Review of the Literature.

    Science.gov (United States)

    Koechlin, Florence M; Fonner, Virginia A; Dalglish, Sarah L; O'Reilly, Kevin R; Baggaley, Rachel; Grant, Robert M; Rodolph, Michelle; Hodges-Mameletzis, Ioannis; Kennedy, Caitlin E

    2016-11-29

    Daily oral pre-exposure prophylaxis (PrEP) is the use of antiretroviral drugs by HIV-negative people to prevent HIV infection. WHO released new guidelines in 2015 recommending PrEP for all populations at substantial risk of HIV infection. To prepare these guidelines, we conducted a systematic review of values and preferences among populations that might benefit from PrEP, women, heterosexual men, young women and adolescent girls, female sex workers, serodiscordant couples, transgender people and people who inject drugs, and among healthcare providers who may prescribe PrEP. A comprehensive search strategy reviewed three electronic databases of articles and HIV-related conference abstracts (January 1990-April 2015). Data abstraction used standardised forms to categorise by population groups and relevant themes. Of 3068 citations screened, 76 peer-reviewed articles and 28 conference abstracts were included. Geographic coverage was global. Most studies (N = 78) evaluated hypothetical use of PrEP, while 26 studies included individuals who actually took PrEP or placebo. Awareness of PrEP was low, but once participants were presented with information about PrEP, the majority said they would consider using it. Concerns about safety, side effects, cost and effectiveness were the most frequently cited barriers to use. There was little indication of risk compensation. Healthcare providers would consider prescribing PrEP, but need more information before doing so. Findings from a rapidly expanding evidence base suggest that the majority of populations most likely to benefit from PrEP feel positively towards it. These same populations would benefit from overcoming current implementation challenges with the shortest possible delay.

  6. Complex and Conflicting Social Norms: Implications for Implementation of Future HIV Pre-Exposure Prophylaxis (PrEP Interventions in Vancouver, Canada.

    Directory of Open Access Journals (Sweden)

    Rod Knight

    Full Text Available HIV Pre-Exposure Prophylaxis (PrEP has been found to be efficacious in preventing HIV acquisition among seronegative individuals in a variety of risk groups, including men who have sex with men and people who inject drugs. To date, however, it remains unclear how socio-cultural norms (e.g., attitudes towards HIV; social understandings regarding HIV risk practices may influence the scalability of future PrEP interventions. The objective of this study is to assess how socio-cultural norms may influence the implementation and scalability of future HIV PrEP interventions in Vancouver, Canada.We conducted 50 interviews with young men (ages 18-24 with a variety of HIV risk behavioural profiles (e.g., young men who inject drugs; MSM. Interviews focused on participants' experiences and perceptions with various HIV interventions and policies, including PrEP.While awareness of PrEP was generally low, perceptions about the potential personal and public health gains associated with PrEP were interconnected with expressions of complex and sometimes conflicting social norms. Some accounts characterized PrEP as a convenient form of reliable protection against HIV, likening it to the female birth control pill. Other accounts cast PrEP as a means to facilitate 'socially unacceptable' behaviour (e.g., promiscuity. Stigmatizing rhetoric was used to position PrEP as a tool that could promote some groups' proclivities to take 'risks'.Stigma regarding 'risky' behaviour and PrEP should not be underestimated as a serious implementation challenge. Pre-implementation strategies that concomitantly aim to improve knowledge about PrEP, while addressing associated social prejudices, may be key to effective implementation and scale-up.

  7. High-tech entrepreneurship

    DEFF Research Database (Denmark)

    Bernasconi, Michel; Harris, Simon; Mønsted, Mette

    ; entrepreneurial finance; marketing technological innovations; and high-tech incubation management. Including case studies to give practical insights into genuine business examples, this comprehensive book has a distinctly 'real-world' focus throughout.Edited by a multi-national team, this comprehensive book......High-tech businesses form a crucial part of entrepreneurial activity - in some ways representing very typical examples of entrepreneurship, yet in some ways representing quite different challenges. The uncertainty in innovation and advanced technology makes it difficult to use conventional economic...... planning models, and also means that the management skills used in this area must be more responsive to issues of risk, uncertainty and evaluation than in conventional business opportunities. Whilst entrepreneurial courses do reflect the importance of high-tech businesses, they often lack the resources...

  8. PREP program annual report, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    A total of thirty-three 9th and 10th grade American Indian students participated in the program. Curricular focal points were environmental science, supported by courses and labs in mathematics, technical writing, and chemistry. The 1994 summer program was the second year of the environmental science focus. The environmental component covered four topics during the month-long program: drinking water, waste water, solid waste pollution, and mining reclamation. The overall goal of the project was to encourage a greater number of the targeted high school students to acquire the necessary skills to succeed in rigorous college academic programs and to enter science-based disciplines. Students participating in the program were involved in a rigorous daily academic program of formal instruction. Participants lived in the residence halls and participated in many aspects of college life, including planned recreational activities. Students were also involved in academic year activities to maintain a heightened awareness and interest in science-based fields. These goals were met and the program was judged to be a success.

  9. Nalco Fuel Tech

    Energy Technology Data Exchange (ETDEWEB)

    Michalak, S.

    1995-12-31

    The Nalco Fuel Tech with its seat at Naperville (near Chicago), Illinois, is an engineering company working in the field of technology and equipment for environmental protection. A major portion of NALCO products constitute chemical materials and additives used in environmental protection technologies (waste-water treatment plants, water treatment, fuel modifiers, etc.). Basing in part on the experience, laboratories and RD potential of the mother company, the Nalco Fuel Tech Company developed and implemented in the power industry a series of technologies aimed at the reduction of environment-polluting products of fuel combustion. The engineering solution of Nalco Fuel Tech belong to a new generation of environmental protection techniques developed in the USA. They consist in actions focused on the sources of pollutants, i.e., in upgrading the combustion chambers of power engineering plants, e.g., boilers or communal and/or industrial waste combustion units. The Nalco Fuel Tech development and research group cooperates with leading US investigation and research institutes.

  10. Tech Gets Physical

    Science.gov (United States)

    Ravage, Barbara

    2011-01-01

    As colleges push for increased efficiencies, facilities departments nationwide are turning more and more to high-tech approaches. Nowhere has this trend been more visible than in the realm of energy consumption, where managers hope to extract significant cost savings. Technology is helping facilities managers achieve significant efficiencies,…

  11. Willingness to use short-term oral pre-exposure prophylaxis (PrEP) by migrant miners and female partners of migrant miners in Mozambique.

    Science.gov (United States)

    Falcao, Joana; Ahoua, Laurence; Zerbe, Allison; di Mattei, Pietro; Baggaley, Rachel; Chivurre, Victor; Mulondo, Prince; Ramiro, Isaias; Dalal, Shona; Morales, Fernando; O'Reilly, Kevin; El-Sadr, Wafaa

    2017-05-04

    Migrant miners from Mozambique who work in South Africa and their partners are at substantial risk for HIV infection. We conducted a cross-sectional study to assess the willingness of migrant miners and female partners of miners to take short-term pre-exposure prophylaxis (PrEP) for prevention of HIV acquisition. The study was conducted in Gaza Province, Mozambique, between September and October 2015. A total of 131 male miners and female partners of male miners completed a questionnaire. Subsequently, 48 in-depth interviews among male miners and female partners of miners and 3 focus-group discussions (6 participants each) among female partners of miners were conducted. Quantitative data were tabulated using Stata. A structured coding scheme was developed and qualitative data were analysed using Atlas.ti. Most participants (94%) were willing to take PrEP for short-term use. Facilitating factors for willingness to use PrEP were concerns about partner's sexual behaviour, desire for pregnancy and one's own sexual behaviour. The main barriers to PrEP use were concerns regarding side-effects, perceived difficulty adhering to daily pill taking and concern about partner/family disapproval. Overall, participants saw potential barriers for PrEP as minor obstacles that could be overcome. The male partner's influence on PrEP use was significant.

  12. The promise and peril of pre-exposure prophylaxis (PrEP): using social science to inform prep interventions among female sex workers.

    Science.gov (United States)

    Syvertsen, Jennifer L; Robertson Bazzi, Angela M; Scheibe, Andrew; Adebajo, Sylvia; Strathdee, Steffanie A; Wechsberg, Wendee M

    2014-09-01

    Advances in biomedical interventions to prevent HIV offer great promise in reducing the number of new infections across sub- Saharan Africa, particularly among vulnerable populations such as female sex workers. Several recent trials testing pre-exposure prophylaxis (PrEP) have demonstrated efficacy, although others have been stopped early for futility. Given the importance and complexities of social and behavioural factors that influence biomedical approaches to prevention, we discuss several key areas of consideration moving forward, including trial participation, adherence strategies, social relationships, and the structural factors that shape PrEP interest, use, and potential effectiveness among female sex workers in sub-Saharan Africa. Our review highlights the importance of involving social scientists in clinical and community-based research on PrEP. We advocate for a shift away from a singular "re-medicalization" of the HIV epidemic to that of a "reintegration" of interdisciplinary approaches to prevention that could benefit female sex workers and other key populations at risk of acquiring HIV.

  13. High tech cheating.

    Science.gov (United States)

    Harper, Mary G

    2006-12-01

    The use of technology has enhanced the convenience, flexibility, and efficiency of both preparatory and continuing education. Unfortunately, academic dishonesty, including plagiarism, has shown a positive correlation with the increased use of technology in education. A review of the literature related to unintended outcomes of the use of technology in nursing education and continuing education was conducted to determine the ethical implications for the nursing profession. Although nursing research dealing with academic and professional misconduct is sparse, evidence suggests that academic dishonesty is a predictor of workplace dishonesty. Given this correlation between unethical classroom behavior and unethical clinical behavior, efforts to staunch academic dishonesty may help allay professional misconduct. A combination of high tech and low tech methods may be used to minimize unethical behaviors among students and practicing professional nurses in order to maintain the integrity of the profession.

  14. How To Start a Prep Physics Course

    Science.gov (United States)

    Wall, Jesse D.

    1998-04-01

    At City College, we follow our mother institution, the University of California at Berkeley, in that we require high school physics as a prerequisite for general college physics and then provide a one-semester prep physics course as an alternative to meet this prerequisite. Many people have asked me how they can start such a course. In traveling about on my sabbatical, doing Physics Of Magic (1) at various schools, I have observed how various schools implement this prerequisite course. I will discuss my observations.

  15. PreP+07: improvements of a user friendly tool to preprocess and analyse microarray data

    Directory of Open Access Journals (Sweden)

    Claros M Gonzalo

    2009-01-01

    Full Text Available Abstract Background Nowadays, microarray gene expression analysis is a widely used technology that scientists handle but whose final interpretation usually requires the participation of a specialist. The need for this participation is due to the requirement of some background in statistics that most users lack or have a very vague notion of. Moreover, programming skills could also be essential to analyse these data. An interactive, easy to use application seems therefore necessary to help researchers to extract full information from data and analyse them in a simple, powerful and confident way. Results PreP+07 is a standalone Windows XP application that presents a friendly interface for spot filtration, inter- and intra-slide normalization, duplicate resolution, dye-swapping, error removal and statistical analyses. Additionally, it contains two unique implementation of the procedures – double scan and Supervised Lowess-, a complete set of graphical representations – MA plot, RG plot, QQ plot, PP plot, PN plot – and can deal with many data formats, such as tabulated text, GenePix GPR and ArrayPRO. PreP+07 performance has been compared with the equivalent functions in Bioconductor using a tomato chip with 13056 spots. The number of differentially expressed genes considering p-values coming from the PreP+07 and Bioconductor Limma packages were statistically identical when the data set was only normalized; however, a slight variability was appreciated when the data was both normalized and scaled. Conclusion PreP+07 implementation provides a high degree of freedom in selecting and organizing a small set of widely used data processing protocols, and can handle many data formats. Its reliability has been proven so that a laboratory researcher can afford a statistical pre-processing of his/her microarray results and obtain a list of differentially expressed genes using PreP+07 without any programming skills. All of this gives support to scientists

  16. Tech-Prep: The School-to-Work Connection in Criminal Justice.

    Science.gov (United States)

    Striegel, David; Gray, Michael

    2000-01-01

    Suggests that community colleges should focus more on academics than on technical skills when preparing students to enter the criminal justice system. Asserts that the technical skills needed by workers in law enforcement can be acquired in the police academy, while crucial critical thinking and writing skills are better taught in the college…

  17. Review of HIV Pre exposure prophylaxis (PrEP) and example of HIV PrEP Toolkit

    Science.gov (United States)

    2017-08-28

    Interventions Aim: to reduce the efficiency of transmission or to shorten the duration of infectiousness Usexual Partners U Sharing Needles Older Age...Program HIV PrEP Portfolio - DoD-wide PrEP experience to date (Beckett, Okulicz, Blaylock/Garges, MHRP/WRAIR*) • Analysis of all DoD beneficiaries

  18. The TechSAT program

    Science.gov (United States)

    Shachar, M.; Lapid, P.

    1992-12-01

    The TechSAT project is described which is intended to establish a wide academic infrastructure for the development of new space technologies. A TechSAT satellite will be used for educational purposes by the academic staff and students as well as by radio amateurs. Tech SAT is a microsatellite weighing 50 kg with 45x45x45 cm dimensions. It is based on a Nadir pointing 3D stabilized platform with body mounted solar panels. The TechSAT hardware includes an autonomous attitude control system, a power supply system, and an onboard computer. Command control and telemetry systems will be based on the amateur radio communications payload.

  19. Potential reduced exposure products (PREPs) in industry trial testimony.

    Science.gov (United States)

    Wayne, Geoffrey Ferris

    2006-12-01

    To identify patterns in trial testimony that may reflect on the intentions or expectations of tobacco manufacturers with regard to the introduction of potential reduced exposure products (PREPs). Research was conducted using the Deposition and Trial Testimony Archive (DATTA) collection of trial testimony and depositions housed online at Tobacco Documents Online (www.tobaccodocuments.org). Relevant testimony was identified through full-text searches of terms indicating PREPs or harm reduction strategies. The role and function of PREPs in testimony were classified according to common and contrasting themes. These were analysed in the context of broader trial arguments and against changes in time period and the market. Analysis of testimony suggests that the failure of PREPs in the market tempered initial industry enthusiasm and made protection of the conventional cigarette market its major priority. The "breakthrough" character of PREPs has been de-emphasised, with trial arguments instead positioning PREPs as simply another choice for consumers. This framework legitimises the sale of conventional brands, and shifts the responsibility for adoption of safer products from the manufacturer to the consumer. Likewise, testimony has abandoned earlier dramatic health claims made with regard to PREPs, which had undermined industry arguments regarding efforts to reduce harm in conventional products. More recent testimony advocates the broad acceptance of independent guidelines that would validate use of health claims and enable the industry to market PREPs to consumers. Trial testimony reflects the changing role and positioning of PREPs by the tobacco industry. The findings are of particular importance with regard to future evaluation and potential regulation of reduced harm products.

  20. Planning a Successful Tech Show

    Science.gov (United States)

    Nikirk, Martin

    2011-01-01

    Tech shows are a great way to introduce prospective students, parents, and local business and industry to a technology and engineering or career and technical education program. In addition to showcasing instructional programs, a tech show allows students to demonstrate their professionalism and skills, practice public presentations, and interact…

  1. New Tech, New Ties:

    DEFF Research Database (Denmark)

    Ling, Richard

    regardless of where they are. But when we are engaged in these intimate conversations with absent friends, what happens to our relationship with the people who are actually in the same room with us? In New Tech, New Ties, Rich Ling examines how the mobile telephone affects both kinds of interactions......—those mediated by mobile communication and those that are face to face. Ling finds that through the use of various social rituals the mobile telephone strengthens social ties within the circle of friends and family—sometimes at the expense of interaction with those who are physically present—and creates what he...... calls "bounded solidarity." Ling argues that mobile communication helps to engender and develop social cohesion within the family and the peer group. Drawing on the work of Emile Durkheim, Erving Goffman, and Randall Collins, Ling shows that ritual interaction is a catalyst for the development of social...

  2. Vigor Clean Tech Inc.

    Energy Technology Data Exchange (ETDEWEB)

    Brubacher-Cressman, Dale [Vigor Clean Tech Inc. (Canada)

    2011-07-01

    On May 5, 2011, the Ontario Waterpower Association hosted the emergent hydro workshop in Peterborough. The first technology presented by Vigor Clean Tech Inc. was a system with a vertical axis which is supported by a floating structure and can provide 10's of kWs. The second one is the PowerPipe, an in-conduit system which can be implemented in existing or new conduits and that generates electricity from excess head pressure in rapidly flowing water transmission pipelines; the PowerPipe can be used in low head or incremental sites. With Vigor's technology it is possible to generate renewable energy economically on a small scale and to leverage under-utilized infrastructures. However, to date, few field applications have been carried out. This presentation provided information on a technology which has the potential to produce a steady supply of reliable renewable energy on a small scale.

  3. PrEP implementation research in Africa: what is new?

    Directory of Open Access Journals (Sweden)

    Frances M Cowan

    2016-10-01

    Full Text Available Introduction: Of the two million new HIV infections in adults in 2014, 70% occurred in sub-Saharan Africa. Several African countries have already approved guidelines for pre-exposure prophylaxis (PrEP for individuals at substantial risk of HIV as part of combination HIV prevention but key questions remain about how to identify and deliver PrEP to those at greatest need. Throughout the continent, individuals in sero-discordant relationships, and members of key populations (sex workers, men who have sex with men (MSM, transgender women and injection drug users are likely to benefit from the availability of PrEP. In addition, adolescent girls and young women (AGYW are at substantial risk in some parts of the continent. It has been estimated that at least three million individuals in Africa are likely to be eligible for PrEP according to WHO's criteria. Tens of demonstration projects are planned or underway across the continent among a range of countries, populations and delivery settings. Discussion: In each of the target populations, there are overarching issues related to (i creating demand for PrEP, (ii addressing supply-side issues and (iii providing appropriate and tailored adherence support. Critical for creating demand for PrEP is the normalization of HIV prevention. Community-level interventions which engage opinion leaders as well as empowerment interventions for those at highest risk will be key. Critical to supply of PrEP is that services are accessible for all, including for stigmatized populations. Establishing accessible integrated services provides the opportunity to address other public health priorities including the unmet need for HIV testing, contraception and sexually transmitted infections treatment. National policies need to include minimum standards for training and quality assurance for PrEP implementation and to address supply chain issues. Adherence support needs to recognize that social and structural factors are likely

  4. AirfoilPrep.py Documentation: Release 0.1.0

    Energy Technology Data Exchange (ETDEWEB)

    Ning, S. A. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-09-01

    AirfoilPrep.py provides functionality to preprocess aerodynamic airfoil data. Essentially, the module is an object oriented version of the AirfoilPrep spreadsheet with additional functionality and is written in the Python language. It allows the user to read in two-dimensional aerodynamic airfoil data, apply three-dimensional rotation corrections for wind turbine applications, and extend the datato very large angles of attack. This document discusses installation, usage, and documentation of the module.

  5. High Tech M&As

    DEFF Research Database (Denmark)

    Toppenberg, Gustav

    2013-01-01

    of findings are not applicable to the high-tech industry; in fact this industry has many additional challenges. In this study, we aim to explore the process of M&A in the high-tech industry by drawing on extant literature and empirical field work. The paper outlines a research project in progress which...... intends to provide theoretical, empirical and practical contributions in answering the research question: what role does Operations and IT play in creating value in high-tech M&As? The research adds a needed perspective on M&A literature by unveiling unique challenges and opportunities faced by the M...

  6. Vulnerable infected populations and street markets for ARVs: Potential implications for PrEP rollout in the USA.

    Science.gov (United States)

    Kurtz, Steven P; Buttram, Mance E; Surratt, Hilary L

    2014-04-01

    Widespread diversion of antiretroviral (ARV) medications to illicit markets has recently been documented among indigent patients in South Florida. The recent approval of ARVs for pre-exposure prophylaxis (PrEP) has the potential to broaden these illicit markets, as high-risk individuals seek ARVs without a prescription or medical supervision. Nonadherence among diverters and unsupervised use of ARVs for treatment or PrEP increase risks of treatment failure, drug resistance, and disease transmission. We report the scope of ARV diversion among substance-using men who have sex with men in South Florida. Structured interviews (N = 515) queried demographics, HIV status, mental distress, substance dependence, and sexual risks. HIV-positive participants answered questions about medical care, treatment, and ARV adherence and diversion. Median age was 39. Of 46.4% who were HIV-positive, 79.1% were prescribed ARVs. Of these, 27% reported selling/trading ARVs. Reasons for diversion were sharing/trading with friends, sale/trade for money/drugs, and sale/trade of unused medications. ARV diverters, compared to nondiverters, were more likely to be substance dependent (74.5% vs. 58.7%, p = 0.046) and have traded sex for money/drugs (60.8% vs. 32.6%, p system. The implications of diversion for increased risks of treatment failure, disease transmission, and PrEP failure should be carefully considered in developing policy and behavioral supports to scaling up treatment as prevention and PrEP.

  7. Willingness to use pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men (MSM) in Malaysia: findings from a qualitative study.

    Science.gov (United States)

    Bourne, Adam; Cassolato, Matteo; Thuan Wei, Clayton Koh; Wang, Bangyuan; Pang, Joselyn; Lim, Sin How; Azwa, Iskandar; Yee, Ilias; Mburu, Gitau

    2017-08-02

    Men who have sex with men (MSM) continue to be disproportionately affected by HIV in Malaysia. Recent success has been observed within demonstration projects examining the efficacy of HIV pre-exposure prophylaxis (PrEP), an antiretroviral -based medication taken by HIV-negative men to prevent sero-conversion. In order for such promising findings to be translated in real-world settings, it is important to understand the acceptability of PrEP, including perceived barriers to access or uptake. As part of a larger mixed-methods study exploring acceptability and willingness to use PrEP among MSM in Malaysia, 19 men took part in audio-recorded focus group discussions hosted by a community-based HIV organization and facilitated by a trained researcher. Discussions focussed on awareness and potential information management, general perceptions of PrEP and potential motivations or barriers to the use of PrEP, including those at the personal, social, health system or structural level. Data were transcribed verbatim and underwent a detailed thematic analysis. Rather than perceiving PrEP as a replacement for condoms in terms of having safer sex, many participants viewed it as an additional layer protection, serving as a crucial barrier to infection on occasions where condom use was intended, but did not occur. It was also perceived as more valuable to "at-risk" men, such as those in HIV sero-discordant relationships or those with a higher number of sexual partners. Elements of discussion tended to suggest that some men taking PrEP may be subject to stigma from others, on the assumption they may be promiscuous or engage in high-risk sexual behaviours. This qualitative study indicates that, broadly speaking, PrEP may be acceptable to MSM in Malaysia. However, in order for its potential to be realized, and uptake achieved, educative interventions are required to inform the target population as to the efficacy and potential, positive impact of PrEP. Given concerns for how those

  8. TechEdSat Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the Technical Education Satellite (TechEdSat) is to employ a small spacecraft to evaluate, demonstrate, and validate two new technologies for...

  9. FinTech Market Development Perspectives

    OpenAIRE

    Kalmykova Ekaterina; Ryabova Anna

    2016-01-01

    Fast development of technologies has led to emergence of the new market – FinTech – which is very attractive for investors today. By now this market has a great number of different concepts: P2P-crediting, E-wallets, Bitcoins, mPOS-acquiring, T-commerce, mobile banks, etc. Many of these tools have already heavily entered our ordinary life. People can obtain any credits through special services on the Internet from other users without participation of banks, pay by credit card using mobile dev...

  10. 新兴经济国家高技术企业创投持股与创新绩效关系研究%Role of Venture Capital Participation in High-Tech Firm’s Innovation in Newly Emerging Economies

    Institute of Scientific and Technical Information of China (English)

    张帆; 吴航; 李飞

    2013-01-01

    As a kind of innovation intermediary agency, venture capital’s participation is vital for high-tech firms innovation through widening the search scope and reducing search cost. Based on the innovation search view, we pick out 149 high-tech firms of China and examine the relationship between venture capital’s participation and innovation performance. The results show that venture capital’s participation has a significantly positive relationship with the innovation performance. We also find that these positive relationships disappear when managers’ perceived industry growth is higher, when new ventures adopt agency businesses for foreign firms, and when the new ventures export.%  创业投资机构作为一种创新中介机构,能够扩大企业创新搜索空间并降低创新搜索成本,因而对于新兴经济国家高技术企业创新具有战略意义。本文基于创新搜索理论,选取中国高技术企业作为研究对象,利用149家高技术企业调研数据对创投持股与企业创新绩效之间的关系机制进行了探索。研究发现,创投持股对企业创新绩效具有显著正向影响;当企业管理者感知的产业增长较高时,为国外企业代理销售产品和服务时,以及企业向国外出口产品或服务时,创投持股对企业创新绩效的影响会降低。

  11. NEXT GENERATION ORAL PrEP: BEYOND TENOFOVIR

    Science.gov (United States)

    Abraham, Bisrat K.; Gulick, Roy

    2013-01-01

    Purpose Clinical trials of oral pre-exposure prophylaxis (PrEP) have focused testing on regimens of tenofovir (TDF) with or without emtricitabine (FTC). However, TDF may be associated with toxicities (renal, bone) and FTC may select for drug resistance. In this review, we discuss agents that might serve as alternatives to TDF/FTC for HIV prevention. Recent Findings Several drug characteristics are important to consider when selecting agents for PrEP with the most critical being safety, tolerability, adequate penetration into target tissues, prevention of HIV infection, and long lasting activity with convenient dosing. With these factors in mind, we review several potentially useful agents for PrEP. The first group includes drugs that are already FDA-approved (maraviroc, raltegravir) with attributes that make them attractive for PrEP. The second groups of drugs include investigational agents with long-lasting activities that are being developed in parenteral form (rilpivirine-long acting, S/GSK 1265744, ibalizumab). Summary Current research suggests there will be a broader array of PrEP drugs to choose from in the near future, thereby giving clinicians the flexibility to select agents that best suit the needs of their patient population. PMID:23032733

  12. Asia's New High-Tech Competitors: An SRS Special Report.

    Science.gov (United States)

    Rausch, Lawrence M.

    This report profiles nine economies linked by Asian identity, yet marked by great economic and technological disparity, in order to project which economies will be full-fledged participants and competitors in tomorrow's high-tech product markets. Based on the various indicators of technological activity and competitiveness presented in this…

  13. Houston Pre-Freshman Enrichment Program (Houston PREP). Final report, June 9, 1997--July 25, 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The 1997 Houston Pre-Freshman Enrichment Program (PREP) was conducted at the campus of the University of Houston-Downtown from June 9 to July 25, 1997. Program participants were recruited from the Greater Houston Area. All participants were identified as high-achieving students with an interest in learning about the engineering and science professions. The goal of the program was to better prepare our pre-college youth prior to entering college as mathematics, science and engineering majors. The program participants were middle school and high school students from the Aldine, Alief, Channel View, Clear Creek, Cypress-Fairbanks, Fort Bend, Galena Park, Houston, Humble, Katy, Klein, North Forest, Pasadena, Private, and Spring Branch Independent School Districts. Of the 194 students starting the program, 165 students were from economically and socially disadvantage groups under-represented in the engineering and science professions, and 118 of the 194 were women. Our First Year group for 1997 composed of 96% minority and women students. Second and Third Year students combined were 96% minority or women. With financial support from the Center for Computational Sciences and Advanced Distributed Simulation, the Fourth Year Program was added to PREP this year. Twelve students completed the program (83% minority or women).

  14. The effects of a prenatal course including PREP for effective family living on self-esteem and parenting attitudes of adolescents: a brief report.

    Science.gov (United States)

    Emmons, R D; Nystul, M S

    1994-01-01

    Nine adolescent females were enrolled in a prenatal course that included the PREP for Effective Family Living Program (the treatment group). Two comparison groups were utilized in this study; one attended the prenatal group without the PREP program, and the second did not attend either the prenatal course or the PREP program. The Coopersmith Self-Esteem Inventory and the Attitude Toward the Freedom of Children Scale (a parental attitude scale) was administered to all participants. No significant difference was found among the three groups in terms of self-concept. A significant difference was found among the three groups in terms of parental attitudes, with the treatment group scoring higher on democratic parenting attitudes than did the two comparison groups.

  15. Correlates of Awareness of and Willingness to Use Pre-exposure Prophylaxis (PrEP) in Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Geosocial-Networking Smartphone Applications in New York City.

    Science.gov (United States)

    Goedel, William C; Halkitis, Perry N; Greene, Richard E; Duncan, Dustin T

    2016-07-01

    Geosocial-networking smartphone applications are commonly used by gay, bisexual, and other men who have sex with men (MSM) to meet sexual partners. The purpose of the current study was to evaluate awareness of and willingness to use pre-exposure prophylaxis (PrEP) among MSM who use geosocial-networking smartphone applications residing in New York City. Recruitment utilizing broadcast advertisements on a popular smartphone application for MSM yielded a sample of 152 HIV-uninfected MSM. Multivariable models were used to assess demographic and behavioral correlates of awareness of and willingness to use PrEP. Most participants (85.5 %) had heard about PrEP but few (9.2 %) reported current use. Unwillingness to use PrEP was associated with concerns about side effects (PR = 0.303; 95 % CI 0.130, 0.708; p = 0.006). Given that more than half (57.6 %) of participants were willing to use PrEP, future research is needed to elucidate both individual and structural barriers to PrEP use among MSM.

  16. The Effect of Metacognitive Strategy Training on Science Process Skills and Science Self Efficacy among First Year Prep Students with Learning Disabilities

    Science.gov (United States)

    Gomaa, Omema Mostafa Kamel

    2016-01-01

    This study investigated the effect of using metacognitive strategy training on science process skills and science self efficacy in learning disabled first year prep students. A total of 60 students identified with LD were invited to participate. The sample was randomly divided into two groups; experimental (n = 30 boys) and control (n = 30 boys ).…

  17. Who should be offered HIV pre-exposure prophylaxis (PrEP)?: A secondary analysis of a Phase 3 PrEP efficacy trial in men who have sex with men and transgender women

    Science.gov (United States)

    Buchbinder, Susan P; Glidden, David V.; Liu, Albert Y.; McMahan, Vanessa; Guanira, Juan V.; Mayer, Kenneth H.; Goicochea, Pedro; Grant, Robert M.

    2014-01-01

    Background Pre-exposure prophylaxis (PrEP) has been proven to reduce HIV acquisition in men who have sex with men and transgender women (MSM/TGW). For maximal impact, PrEP should be targeted to subpopulations accounting for the largest proportion of infections (population attributable fraction, PAF) and for whom the number needed to treat (NNT) to prevent infection is lowest. Methods The iPrEx study was a randomized controlled efficacy trial of tenofovir-disoproxil-fumarate/emtricitabine PrEP in 2499 MSM/TGW on 4 continents. We calculated the association between demographic and risk behavior during screening with subsequent seroconversion among placebo recipients using a Poisson model, and the PAF and NNT for risk behavior subgroups. Findings Of 1248 placebo participants enrolled, 83 became HIV infected in follow-up. Participants reporting non-condom receptive anal intercourse (ncRAI) seroconverted significantly more often than MSM/TGW reporting no condomless anal sex (adjusted hazard ratio (AHR) 5·11, 95% CI 1·55-16·79). The overall PAF for MSM/TGW reporting ncRAI was 64% (prevalence=60%). Most of this risk came from ncRAI with unknown serostatus partners (PAF 53%, prevalence=54%, AHR 4·76); in contrast, the PAF for ncRAI with an HIV positive partner, an uncommon practice, was only 1% (prevalence 1%, AHR=7·11). The overall NNT per year for the cohort was 62 (95% CI 44-147). NNTs were lower for MSM/TGW self-reporting ncRAI, cocaine use, or a sexually transmitted infection (NNT= 36, 12, and 41 respectively). Having a single partner or non-condom insertive anal sex had the highest NNTs. Interpretation PrEP may be most effective at a population level if targeted toward MSM/TGW reporting ncRAI, even with partners perceived to be HIV negative. Substance use history and testing for STIs may also inform individual decisions to start PrEP. Considering PAF and NNT can aid in discussing the benefits and risks of PrEP with MSM/TGW. Funding Funded by the National

  18. 高新技术制造企业服务化绩效研究--基于员工胜任力和顾客参与水平的调节效应%Research on Servitization Performance of High-tech Manufacturing Enterprises-Based on Regulating Effects of Employee Competency and Customer Participation

    Institute of Scientific and Technical Information of China (English)

    孙文清

    2016-01-01

    文章基于探究影响我国高新技术制造企业服务化绩效的边界条件的研究目的,构建了员工胜任力和顾客参与(水平)对企业服务化绩效的调节模型。依据对江苏、山东、广东和浙江四个省份62家高新技术制造企业的调查数据,运用分层回归分析法检验了员工胜任力和顾客参与对“提供服务—企业绩效”模型的调节效应,运用分组回归分析法检验了顾客参与水平对“提供服务—企业绩效”模型的调节效应。研究结论表明,中、高水平的顾客参与、员工技能和员工态度存在显著正向调节影响,低水平顾客参与存在负向调节影响。%For the purpose of investigating boundary conditions affecting the servitization of high-tech manufacturing enter⁃prises,a model that the regulating effects of employee competencies and customer participation on business performance is made. Based on the survey on 62 high-tech manufacturing enterprises in four provinces of Jiangsu,Shandong,Guangdong and Zhejiang,the hierarchical regression analysis method is adopted to test the regulating effects of employee competencies and customer participation on“service delivery–business performance”model;the grouping regression analysis method is employed to test the regulating effects of customer participation on“service delivery–business performance”model. It is con⁃cluded that the high customer participation,employee competencies and attitudes have positive effects and the low customer participation has negative effects.

  19. High pre-exposure prophylaxis uptake and early adherence among men who have sex with men and transgender women at risk for HIV Infection: the PrEP Brasil demonstration project.

    Science.gov (United States)

    Hoagland, Brenda; Moreira, Ronaldo I; De Boni, Raquel B; Kallas, Esper G; Madruga, José Valdez; Vasconcelos, Ricardo; Goulart, Silvia; Torres, Thiago S; Marins, Luana M S; Anderson, Peter L; Luz, Paula M; Costa Leite, Iuri da; Liu, Albert Y; Veloso, Valdilea G; Grinsztejn, Beatriz

    2017-04-06

    The efficacy of pre-exposure prophylaxis (PrEP) in preventing sexual acquisition of human immunodeficiency virus (HIV) is well established. Little is known about the feasibility of PrEP implementation in middle-income settings with concentrated epidemics among men who have sex with men (MSM) and transgender women (TGW). PrEP Brasil is a prospective, multicentre, open-label demonstration project assessing PrEP delivery in the context of the Brazilian Public Health System. HIV-uninfected MSM and TGW in 3 referral centres in Rio de Janeiro and São Paulo were evaluated for eligibility and offered 48 weeks of daily emtricitabine/tenofovir for PrEP. Concentrations of tenofovir diphosphate in dried blood spot samples (DBS) at week 4 after enrolment (early adherence) were measured. Predictors of drug levels were assessed using ordinal logistic regression models considering the DBS drug level as a 3 level variable (<350 fmol/punch, ≥350-699 fmol/punch and ≥700 fmol/punch). 1,270 individuals were assessed for participation; n = 738 were potentially eligible and n = 450 were offered PrEP (PrEP uptake was 60.9%). Eligible but not enrolled individuals were younger, had lower HIV risk perception and had lower PrEP awareness. At week 4, 424 participants (of the 450 enrolled) had DBS TFV-DP concentrations, 94.1% in the protective range (≥350 fmol/punch, consistent with ≥2 pills per week), and 78% were in the highly protective range (≥700 fmol/punch, ≥4 pills per week). Participants with ≥12 years of schooling had 1.9 times the odds (95%CI 1.10-3.29) of a higher versus lower drug level than participants with <12 years of schooling. Condomless receptive anal intercourse in the prior 3 months was also associated with higher drug levels (adjusted OR = 1.78; 95% CI 1.08-2.94). The high uptake and early adherence indicate that PrEP for high-risk MSM and TGW can be successfully delivered in the context of the Brazilian Public Health System. Interventions to

  20. CROPS : high tech agricultural robots

    NARCIS (Netherlands)

    Bontsema, J.; Hemming, J.; Pekkeriet, E.J.

    2014-01-01

    In the EU-funded CROPS (Clever Robots for Crops) project high tech robots are developed for site-specific spraying and selective harvesting of fruit and fruit vegetables. The harvesting robots are being designed to harvest high-value crops such as greenhouse vegetables, fruits in orchards and grapes

  1. SPC-Prep. Instructor's Guide. Workplace Education. Project ALERT.

    Science.gov (United States)

    Ruetz, Nancy

    This instructor's guide contains materials for a course designed to prepare employees for statistical process control (SPC) training given at their workplace by refreshing math skills and building the concepts and vocabulary necessary to understand SPC in manufacturing environments. SPC-Prep 1 addresses the math skills necessary to perform SPC…

  2. Comparison of ThinPrep preparations to other preparation types in gastrointestinal cytology: observations from the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology.

    Science.gov (United States)

    Clayton, Amy C; Bentz, Joel S; Wasserman, Patricia G; Schwartz, Mary R; Souers, Rhona J; Chmara, Beth Anne; Laucirica, Rodolfo; Clary, Karen M; Moriarty, Ann T

    2010-08-01

    Differences in participant responses for ThinPrep (TP) and non-ThinPrep (NTP) preparations for gastrointestinal cytology challenges, which circulated in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology (CAP NGC), may help to identify performance variations between preparation types. To compare the performance of TP-prepared slides of gastrointestinal exfoliative cytology specimens to that of NTP preparations in the CAP NGC program. Participant responses between 2000 and 2007 were evaluated for esophageal wash/brush, gastric wash/brush, and biliary tract brush specimens with a reference diagnosis of adenocarcinoma, squamous cell carcinoma, carcinoid, or spindle cell neoplasm. ThinPrep challenges were compared with NTP preparations (conventional smears, cytospins) for discordant responses. In all, 6023 pathologist responses and 3825 cytotechnologist responses were reviewed. Non-ThinPrep preparations comprised 93% (n = 11 588) of the challenges, while 7% (n = 912) were TP material. A match for a "positive/suspicious" diagnosis was seen in 88.5% of NTP and 95.9% of TP preparations (P cytology specimens circulated in an interlaboratory comparison program. Performance varied by reference interpretation, with the best performance for the interpretation of adenocarcinoma. Cytotechnologists and pathologists performed at the same level overall, but with differences for the diagnosis of spindle cell neoplasm and squamous carcinoma.

  3. HIV-negative male couples' attitudes about pre-exposure prophylaxis (PrEP) and using PrEP with a sexual agreement.

    Science.gov (United States)

    Mitchell, Jason W; Lee, Ji-Young; Woodyatt, Cory; Bauermeister, José; Sullivan, Patrick; Stephenson, Rob

    2016-08-01

    One efficacious strategy to help prevent HIV is oral pre-exposure prophylaxis (PrEP), a daily regimen of antiretroviral treatment taken by HIV-negative individuals. Two of the recommendations of Centers for Disease Control and Prevention (CDC) guidelines for PrEP pertain to being in a relationship (i.e., male couples). Despite the recognition of how primary partners in male couples' relationships shape HIV risk and CDC's PrEP guidelines, there is a paucity of data that examine HIV-negative male couples' attitudes toward PrEP use and using PrEP with a sexual agreement. A sexual agreement is an explicit agreement made between two individuals about what sex and other related behaviors may occur within and outside of their relationship. In this qualitative study, we examine HIV-negative male couples' attitudes toward PrEP use and whether they thought PrEP could be integrated into a sexual agreement. Data for this study are drawn from couple-level interviews conducted in 2014 with 29 HIV-negative male couples who had a sexual agreement and were from Atlanta or Detroit. Both passive (e.g., flyers) and active (e.g., targeted Facebook advertisements) recruitment methods were used; the sample was stratified by agreement type. Thematic analysis was applied to identify the following themes regarding HIV-negative male couples' attitudes toward PrEP use: (1) PrEP and condom use; (2) concerns about PrEP (e.g., effectiveness, side effects, and promoting sexually risky behavior); and (3) accessibility of PrEP. Some thought PrEP could be a part of couples' agreement because it could help reduce sexual anxiety and sexual risk, and would help keep the couple safe. Others described PrEP use with an agreement as something for "others". Some were also concerned that incorporating PrEP could usurp the need for a sexual agreement in a couples' relationship. These themes highlight the need to improve informational messaging and promotion efforts about PrEP among HIV-negative male couples

  4. PrEP in Europe – expectations, opportunities and barriers

    Science.gov (United States)

    McCormack, Sheena Mary; Noseda, Veronica; Molina, Jean-Michel

    2016-01-01

    Introduction In contrast to the global trend showing a decline in new HIV infections, the number reported in the World Health Organization (WHO) region of Europe is increasing. Health systems are disparate, but even countries with free access to screening and treatment observe continuing high rates of new infections in key populations, notably men who have sex with men (MSM). Pre-exposure prophylaxis (PrEP) is only available in France. This commentary describes the European epidemics and healthcare settings where PrEP could be delivered, how need might be estimated for MSM and the residual barriers to access. Discussion Health systems and government commitment to HIV prevention and care, both financial and political, differ considerably between the countries that make up Europe. A common feature is that funds for prevention are a small fraction of funds for care. Although care is generally good, access is limited in the middle-income countries of Eastern Europe and central Asia, and only 19% of people living with HIV received antiretroviral therapy in 2014. It is challenging to motivate governments or civil society to implement PrEP in the context of this unmet treatment need, which is driven by limited national health budgets and diminishing assistance from foreign aid. The high-income countries of Western Europe have hesitated to embrace PrEP for different reasons, initially due to key gaps in the evidence. Now that PrEP has been shown to be highly effective in European MSM in two randomized controlled trials, it is clear that the major barrier is the cost of the drug which is still on patent, although inadequate health systems and diminishing investment in civil society are also key challenges to overcome. Conclusions The momentum to implement PrEP in European countries is increasing and provides a welcome opportunity to expand and improve clinical services and civil society support focused on HIV and related infections including other sexually transmitted and

  5. Protocol for an open-label, single-arm trial of HIV pre-exposure prophylaxis (PrEP) among people at high risk of HIV infection: the NSW Demonstration Project PRELUDE

    Science.gov (United States)

    Vaccher, S; Grulich, A; McAllister, J; Templeton, D J; Bloch, M; McNulty, A; Holden, J; Poynten, I M; Prestage, G; Zablotska, I

    2016-01-01

    Introduction Despite a number of HIV prevention strategies, the number of new HIV infections remains high. In Australia, over three-quarters of new HIV diagnoses are in gay and bisexual men (GBM). Pre-exposure prophylaxis (PrEP) has been shown to be effective at preventing new HIV infections in several randomised trials. The PRELUDE study aims to evaluate the implementation of PrEP in healthcare settings in New South Wales (NSW), Australia, among a sample of high-risk adults. Methods and analysis PRELUDE is an ongoing open-label, single-arm demonstration project, conducted in public and private clinics across NSW, Australia. Enrolment began in November 2014. The study is designed for 300 high-risk participants—mainly GBM and heterosexual women. Participants receive daily oral PrEP, composed of emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF), for up to 2.5 years. Quarterly study visits include testing for HIV and sexually transmitted infections (STIs), assessment of ongoing eligibility and side effects, and self-reported adherence. Following each study visit, online behavioural surveys are administered to collect information on medication adherence, risk behaviours and attitudes. Blood samples will be collected in a subset of patients 1, 6 and 12 months after PrEP initiation to measure FTC/TDF concentrations. Analyses using longitudinal regression models will focus on feasibility, adherence, safety, tolerability and effects of PrEP on behaviour. This study will inform PrEP policy and guide the implementation of PrEP in Australia in people at high risk of HIV. Ethics and dissemination The study will be conducted in accordance with the Declaration of Helsinki. All patients will provide written informed consent prior to participation in the study. Publications relating to each of the primary end points will be gradually released after 12 months of follow-up is complete. Trial registration number NCT02206555; Pre-results. PMID:27324719

  6. Instructional and Organizational Effectiveness in Selected PREPS-Identified Value Added and PREPS-Identified Value Subtracted Elementary Schools in Mississippi

    Science.gov (United States)

    Henderson, Jimmy Dale

    2011-01-01

    This study examined the perceptions of principals, teachers, and support staff at 3 PREPS-identified value added and three PREPS-identified value subtracted elementary schools in Mississippi to determine if there were "effective schools" practices in the areas of instructional and organizational systems that were unique to either group. The…

  7. PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers

    Directory of Open Access Journals (Sweden)

    Iryna Zablotska

    2016-10-01

    Full Text Available Introduction: HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM and other key populations. Pre-exposure prophylaxis (PrEP is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards PrEP implementation in the Asia-Pacific region, including opportunities and barriers. Discussion: Awareness about PrEP in the Asia-Pacific is still low and so are its levels of use. A high proportion of MSM who are aware of PrEP are willing to use it. Key PrEP implementation barriers include poor knowledge about PrEP, limited access to PrEP, weak or non-existent HIV prevention programmes for MSM and other key populations, high cost of PrEP, stigma and discrimination against key populations and restrictive laws in some countries. Only several clinical trials, demonstration projects and a few larger-scale implementation studies have been implemented so far in Thailand and Australia. However, novel approaches to PrEP implementation have emerged: researcher-, facility- and community-led models of care, with PrEP services for fee and for free. The WHO consolidated guidelines on HIV testing, treatment and prevention call for an expanded access to PrEP worldwide and have provided guidance on PrEP implementation in the region. Some countries like Australia have released national PrEP guidelines. There are growing community leadership and consultation processes to initiate PrEP implementation in Asia and the Pacific. Conclusions: Countries of the Asia-Pacific region will benefit from adding PrEP to their HIV prevention packages, but for many this is a critical step that requires resourcing. Having an impact on the HIV epidemic requires investment. The next years should see the region transitioning from limited PrEP implementation projects to growing access to PrEP and expansion of HIV prevention programmes.

  8. PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers

    Science.gov (United States)

    Zablotska, Iryna; Grulich, Andrew E; Phanuphak, Nittaya; Anand, Tarandeep; Janyam, Surang; Poonkasetwattana, Midnight; Baggaley, Rachel; van Griensven, Frits; Lo, Ying-Ru

    2016-01-01

    Introduction HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM) and other key populations. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards PrEP implementation in the Asia-Pacific region, including opportunities and barriers. Discussion Awareness about PrEP in the Asia-Pacific is still low and so are its levels of use. A high proportion of MSM who are aware of PrEP are willing to use it. Key PrEP implementation barriers include poor knowledge about PrEP, limited access to PrEP, weak or non-existent HIV prevention programmes for MSM and other key populations, high cost of PrEP, stigma and discrimination against key populations and restrictive laws in some countries. Only several clinical trials, demonstration projects and a few larger-scale implementation studies have been implemented so far in Thailand and Australia. However, novel approaches to PrEP implementation have emerged: researcher-, facility- and community-led models of care, with PrEP services for fee and for free. The WHO consolidated guidelines on HIV testing, treatment and prevention call for an expanded access to PrEP worldwide and have provided guidance on PrEP implementation in the region. Some countries like Australia have released national PrEP guidelines. There are growing community leadership and consultation processes to initiate PrEP implementation in Asia and the Pacific. Conclusions Countries of the Asia-Pacific region will benefit from adding PrEP to their HIV prevention packages, but for many this is a critical step that requires resourcing. Having an impact on the HIV epidemic requires investment. The next years should see the region transitioning from limited PrEP implementation projects to growing access to PrEP and expansion of HIV prevention programmes. PMID:27760688

  9. Houston prefreshman enrichment program (Houston PREP). Final report, June 10, 1996--August 1, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The 1996 Houston Pre-freshman Enrichment Program (PREP) was conducted on the campus of the University of Houston-Downtown from June 10 to August 1, 1996. Program Participants were recruited from the Greater Houston area. All participants were identified as high achieving students with an interest in learning about the engineering and science professions. The goal of the program was to better prepare our pre-college youth prior to entering college as mathematics, science and engineering majors. The program participants were middle school and high school students from the Aldine, Alief, Channel View, Crockett, Cypress-Fairbanks, Fort Bend, Galena Park, Houston, Humble, Katy, Klein, North Forest, Pasadena, Private, and Spring Branch Independent School Districts. Of the 197 students starting the program, 170 completed, 142 students were from economically and socially disadvantage groups underrepresented in the engineering and science professions, and 121 of the 197 were female. Our First Year group for 1996 composed of 96% minority and women students. Our Second and Third Year students were 100% and 93.75% minority or women respectively. This gave an overall minority and female population of 93.75%. This year, special efforts were again made to recruit students from minority groups, which caused a significant increase in qualified applicants. However, due to space limitations, 140 applicants were rejected. Investigative and discovery learning were key elements of PREP. The academic components of the program included Algebraic Structures, Engineering, Introduction to Computer Science, Introduction to Physics, Logic and Its Application to Mathematics, Probability and Statistics, Problem Solving Seminar using computers and PLATO software, SAT Preparatory Seminars, and Technical Writing.

  10. Time-Dependent Effect of Chlorhexidine Surgical Prep

    Science.gov (United States)

    2011-10-15

    skin prep prior to venous puncture for blood cultures has resulted in a lower false-positive ratewhen compared to non-alcoholic povidoneeiodine.9...vascular catheter-site care: a meta-analysis. Ann Intern Med 2002;136:792e801. 9. Caldeira D, David C, Sampaio C. Skin antiseptics in venous puncture -site...load throughout the entire duration of the study. Regarding skin preparation prior to insertion of central venous pressure catheters, the current

  11. Meaning-making in the industrialized test prep classroom

    OpenAIRE

    2011-01-01

    Evidence for the efficacy of test-mimicking pedagogical practices anchored to "non-controversial topics" - what one researcher has referred to as the "McDonaldisation of English" and another, the "TOEFLizing of teaching" - is scarce. Though complex, the crux of the problem is 'negative washback' (the subordination of teaching to the dictates of the international proficiency assessment market) and 'test score pollution' (inflated prep-induced test results). This paper explores the issue in sev...

  12. Pathogen-Reduced, Platelet Additive Solution, Extended Stored Platelets (PREPS)

    Science.gov (United States)

    2015-10-01

    associated sepsis remains the principal lethal risk associated with platelet transfusion. Cold storage (4°C) is known to reduce post transfusion...and no residual radiation is detectable . *P-selectin samples will be prepped on end of storage day and batch tested. **Bacterial Culture sample...temperature controlled room until such time as they have no detectable residual radiation. This is generally about 3-4 months. At that point they are

  13. Running-gear Tech 2001; Fahrwerk-Tech 2001. Tagung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Dynamic driving characteristics, active safety and high comfort are conflicting goals which can be combined by active vehicle management systems. The conference discussed modern tools and methods in the fields of design, simulation and experiment. [German] Im Zielkonflikt zwischen Fahrdynamik, aktiver Sicherheit und Komfort bieten Fahrzeugregelsysteme enorme Moeglichkeiten. Systeme fuer Bremsen, Stabilisierung, Daempfung, Aufbaukontrolle und Fahrerassistenz werden in der Zukunft zu einem Fahrwerksmanagement verschmelzen. Diese Fahrzeugintelligenz erfordert moderne Tools und Methoden im Bereich Konzeption, Simulation und Versuch. Die Tagung Fahrwerk-Tech 2001 wird das Fahrwerk in dieser Gesamtheit betrachten und Experten aus den verschiedenen Bereichen zusammen bringen. (orig.)

  14. Allergic contact dermatitis to gamma-irradiated WEBCOL alcohol prep pads.

    Science.gov (United States)

    Firoz, Elnaz F; Turnbull, Rowena K; Loomis, Cynthia A; Brownell, Isaac

    2013-01-01

    We report a case of allergic contact dermatitis to WEBCOL(®) alcohol prep pads in a healthy 17-year-old girl who showed no reaction to the individual components of the prep pads upon provocative use testing. Although several case reports have described allergic contact dermatitis to isopropyl alcohol, there have been no reports of allergic contact dermatitis to alcohol prep pads sterilized with gamma irradiation, a common sterilization technique capable of producing volatile products in this type of alcohol prep pad.

  15. Acceptability of an open-label wait-listed trial design: Experiences from the PROUD PrEP study

    Science.gov (United States)

    Brodnicki, Elizabeth; Desai, Monica; McCormack, Sheena; Nutland, Will; Wayal, Sonali; White, Ellen; Wood, Gemma; Barber, Tristan; Bell, Gill; Clarke, Amanda; Dolling, David; Dunn, David; Fox, Julie; Haddow, Lewis; Lacey, Charles; Nardone, Anthony; Quinn, Killian; Rae, Caroline; Reeves, Iain; Rayment, Michael; White, David; Apea, Vanessa; Ayap, Wilbert; Dewsnap, Claire; Collaco-Moraes, Yolanda; Schembri, Gabriel; Sowunmi, Yinka; Horne, Rob

    2017-01-01

    Background PROUD participants were randomly assigned to receive pre-exposure prophylaxis (PrEP) immediately or after a deferred period of one-year. We report on the acceptability of this open-label wait-listed trial design. Methods Participants completed an acceptability questionnaire, which included categorical study acceptability data and free-text data on most and least liked aspects of the study. We also conducted in-depth interviews (IDI) with a purposely selected sub-sample of participants. Results Acceptability questionnaires were completed by 76% (415/544) of participants. After controlling for age, immediate-group participants were almost twice as likely as deferred-group participants to complete the questionnaire (AOR:1.86;95%CI:1.24,2.81). In quantitative data, the majority of participants in both groups found the wait-listed design acceptable when measured by satisfaction of joining the study, intention to remain in the study, and interest in joining a subsequent study. However, three-quarters thought that the chance of being in the deferred-group might put other volunteers off joining the study. In free-text responses, data collection tools were the most frequently reported least liked aspect of the study. A fifth of deferred participants reported ‘being deferred’ as the thing they least liked about the study. However, more deferred participants disliked the data collection tools than the fact that they had to wait a year to access PrEP. Participants in the IDIs had a good understanding of the rationale for the open-label wait-listed study design. Most accepted the design but acknowledged they were, or would have been, disappointed to be randomised to the deferred group. Five of the 25 participants interviewed reported some objection to the wait-listed design. Conclusion The quantitative and qualitative findings suggest that in an environment where PrEP was not available, the rationale for the wait-listed trial design was well understood and

  16. High-tech meets end-user

    NARCIS (Netherlands)

    Steen, M.

    2008-01-01

    One challenge within the high-tech sector is to develop products that end users will actually need and will be able to use. One way of trying to match the design of high-tech products to the needs of end users, is to let researchers and designers interact with them via a human-centred design (HCD) a

  17. The Safety of Tenofovir-Emtricitabine for HIV Pre-Exposure Prophylaxis (PrEP) in Individuals With Active Hepatitis B.

    Science.gov (United States)

    Solomon, Marc M; Schechter, Mauro; Liu, Albert Y; McManhan, Vanessa M; Guanira, Juan V; Hance, Robert J; Chariyalertsak, Suwat; Mayer, Kenneth H; Grant, Robert M

    2016-03-01

    Pre-exposure prophylaxis (PrEP) with daily oral emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) prevents HIV infection. The safety and feasibility of HIV PrEP in the setting of hepatitis B virus (HBV) infection were evaluated. The Iniciativa Profilaxis Pre-Exposición study randomized 2499 HIV-negative men and transgender women who have sex with men to once-daily oral FTC/TDF versus placebo. Hepatitis serologies and transaminases were obtained at screening and at the time PrEP was discontinued. HBV DNA was assessed by polymerase chain reaction, and drug resistance was assessed by population sequencing. Vaccination was offered to individuals susceptible to HBV infection. Of the 2499 participants, 12 (0.5%; including 6 randomized to FTC/TDF) had chronic HBV infection. After stopping FTC/TDF, 5 of the 6 participants in the active arm had liver function tests performed at follow-up. Liver function tests remained within normal limits at post-stop visits except for a grade 1 elevation in 1 participant at post-stop week 12 (alanine aminotransferase = 90, aspartate aminotransferase = 61). There was no evidence of hepatic flares. Polymerase chain reaction of stored samples showed that 2 participants in the active arm had evidence of acute HBV infection at enrollment. Both had evidence of grade 4 transaminase elevations with subsequent resolution. Overall, there was no evidence of TDF or FTC resistance among tested genotypes. Of 1633 eligible for vaccination, 1587 (97.2%) received at least 1 vaccine; 1383 (84.7%) completed the series. PrEP can be safely provided to individuals with HBV infection if there is no evidence of cirrhosis or substantial transaminase elevation. HBV vaccination rates at screening were low globally, despite recommendations for its use, yet uptake and efficacy were high when offered.

  18. The Safety of Tenofovir–Emtricitabine for HIV Pre-Exposure Prophylaxis (PrEP) in Individuals With Active Hepatitis B

    Science.gov (United States)

    Schechter, Mauro; Liu, Albert Y.; McManhan, Vanessa M.; Guanira, Juan V.; Hance, Robert J.; Chariyalertsak, Suwat; Mayer, Kenneth H.; Grant, Robert M.

    2016-01-01

    Background: Pre-exposure prophylaxis (PrEP) with daily oral emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) prevents HIV infection. The safety and feasibility of HIV PrEP in the setting of hepatitis B virus (HBV) infection were evaluated. Methods: The Iniciativa Profilaxis Pre-Exposición study randomized 2499 HIV-negative men and transgender women who have sex with men to once-daily oral FTC/TDF versus placebo. Hepatitis serologies and transaminases were obtained at screening and at the time PrEP was discontinued. HBV DNA was assessed by polymerase chain reaction, and drug resistance was assessed by population sequencing. Vaccination was offered to individuals susceptible to HBV infection. Results: Of the 2499 participants, 12 (0.5%; including 6 randomized to FTC/TDF) had chronic HBV infection. After stopping FTC/TDF, 5 of the 6 participants in the active arm had liver function tests performed at follow-up. Liver function tests remained within normal limits at post-stop visits except for a grade 1 elevation in 1 participant at post-stop week 12 (alanine aminotransferase = 90, aspartate aminotransferase = 61). There was no evidence of hepatic flares. Polymerase chain reaction of stored samples showed that 2 participants in the active arm had evidence of acute HBV infection at enrollment. Both had evidence of grade 4 transaminase elevations with subsequent resolution. Overall, there was no evidence of TDF or FTC resistance among tested genotypes. Of 1633 eligible for vaccination, 1587 (97.2%) received at least 1 vaccine; 1383 (84.7%) completed the series. Conclusions: PrEP can be safely provided to individuals with HBV infection if there is no evidence of cirrhosis or substantial transaminase elevation. HBV vaccination rates at screening were low globally, despite recommendations for its use, yet uptake and efficacy were high when offered. PMID:26413853

  19. Application of the ThinPrep Imaging System in Urine Cytology A Prospective Study

    NARCIS (Netherlands)

    van Hemel, Bettien M.; Haarsma, Jolanda G.; Ruitenbeek, Teus; Groen, Henk; Suurmeijer, Albert J. H.

    2013-01-01

    BACKGROUND In this prospective study, for the first time, the authors compared the accuracy of reading urine specimens using the ThinPrep Imager System (TIS) with the accuracy of conventional screening for the detection of abnormal urine cells. METHODS ThinPrep slides were made from 1455 urine speci

  20. Charter Schools as Nation Builders: Democracy Prep and Civic Education. Policy Brief 4

    Science.gov (United States)

    Lautzenheiser, Daniel; Kelly, Andrew P.

    2013-01-01

    This policy brief is the first in a series of in-depth case studies exploring how top-performing charter schools have incorporated civic learning in their school curriculum and school culture. This paper introduces Democracy Prep, a network of seven public charter schools with a civic mission at its core. Democracy Prep's founder and…

  1. Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.

    Directory of Open Access Journals (Sweden)

    Kentaro Yoshioka

    Full Text Available Prep1, a TALE-family homeodomain transcription factor, has been demonstrated to play a critical role in embryonic hematopoiesis, as its insufficiency caused late embryonic lethality associated with defective hematopoiesis and angiogenesis. In the present study, we generated hematopoietic- and endothelial cell-specific Prep1-deficient mice and demonstrated that expression of Prep1 in the hematopoietic cell compartment is not essential for either embryonic or adult hematopoiesis, although its absence causes significant hematopoietic abnormalities in the adult bone marrow. Loss of Prep1 promotes cell cycling of hematopoietic stem/progenitor cells (HSPC, leading to the expansion of the HSPC pool. Prep1 deficiency also results in the accumulation of lineage-committed progenitors, increased monocyte/macrophage differentiation and arrested erythroid maturation. Maturation of T cells and B cells is also perturbed in Prep-deficient mice. These findings provide novel insight into the pleiotropic roles of Prep1 in adult hematopoiesis that were unrecognized in previous studies using germline Prep1 hypomorphic mice.

  2. Mechatronics education at Virginia Tech

    Science.gov (United States)

    Bay, John S.; Saunders, William R.; Reinholtz, Charles F.; Pickett, Peter; Johnston, Lee

    1998-12-01

    The advent of more complex mechatronic systems in industry has introduced new opportunities for entry-level and practicing engineers. Today, a select group of engineers are reaching out to be more knowledgeable in a wide variety of technical areas, both mechanical and electrical. A new curriculum in mechatronics developed at Virginia Tech is starting to bring students from both the mechanical and electrical engineering departments together, providing them wit an integrated perspective on electromechanical technologies and design. The course is cross-listed and team-taught by faculty from both departments. Students from different majors are grouped together throughout the course, each group containing at least one mechanical and one electrical engineering student. This gives group members the ability to learn from one another while working on labs and projects.

  3. The 11th High-Tech Expo

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The 11th China Beijing International High-Tech Expo,themed as "high-tech Olympics and high-tech innovation",was rounded off successfully on the afternoon of May 25.The Expo,held as planned in such a special period of post-quake relief work,has shown us the power of technology and scientific spirit.It has not only given all the Chinese people the spiritual support and hope for the future but also opened a window for the international community to know more about the Beijing Oympic Games and the development of science and technology in China.

  4. Automated screening versus manual screening: a comparison of the ThinPrep imaging system and manual screening in a time study.

    Science.gov (United States)

    Schledermann, Doris; Hyldebrandt, Tina; Ejersbo, Dorthe; Hoelund, Berit

    2007-06-01

    The ThinPrep Imaging System (TIS) is an automated system that assists cytotechnologists in the primary screening of ThinPrep liquid based cervical samples. Between June 1, 2004, and April 1, 2005, four experienced cytotechnologists participated in the study in which the duration of the screening procedure was timed for each of the 11,354 slides included. In every slide 22 fields of view were reviewed, and the samples that contained potentially abnormal cells were fully screened. The screening time was reduced by 42% (mean) (p < 0.001). By manual rescreening of the negative TIS samples, abnormal cells were found in 10 samples (false negative rate 0.14%). In every case the abnormal cells had been identified by the scanner, but misinterpreted by the cytotechnologist. These findings stressed the importance of carefulness in the interpretation of the marked fields and beyond that helped the cytotechnologists and pathologists to have more confidence in the automated system.

  5. FinTech Market Development Perspectives

    Directory of Open Access Journals (Sweden)

    Kalmykova Ekaterina

    2016-01-01

    Full Text Available Fast development of technologies has led to emergence of the new market – FinTech – which is very attractive for investors today. By now this market has a great number of different concepts: P2P-crediting, E-wallets, Bitcoins, mPOS-acquiring, T-commerce, mobile banks, etc. Many of these tools have already heavily entered our ordinary life. People can obtain any credits through special services on the Internet from other users without participation of banks, pay by credit card using mobile devices, and get information about expenses and incomes according to the card anywhere in the world. Users do not need to go to banks anymore and to spend their time for credit arrangements, currency exchange, to look for ATMs to remove cash. Purchases on the Internet can be paid not only in rubles, but also in new digital currency. These tools make life easier, however, they pose a serious threat for banks. Now, bank institutions should create more convenient and utility services for the clients to keep clients. Therefore, bank and credit systems start to change actively.

  6. Preventing Tech Aches: Using Smart Phones Wisely

    Science.gov (United States)

    ... Media Guidelines Copyright Permissions Preventing Tech Aches: Using Smart Phones Wisely BETHESDA, MD (Dec. 26, 2013) — If you received a new smart phone or tablet this holiday season, chances are you’ ...

  7. Human capital in low-tech manufacturing

    DEFF Research Database (Denmark)

    Hansen, Teis; Winther, Lars; Hansen, Ronnie Fibæk

    2014-01-01

    capital appears to be equally important for economic development in low-tech industries and, second, that the divide between the large urban regions, especially Copenhagen, and the rest of the country plays the primary role in explaining the geography of human capital. These findings stress the relevance......An essential feature associated with the rise of the knowledge economy has been the increasing focus on the importance of human capital as a precondition for economic growth. Human capital has been found to have a positive impact on the economic growth of high-tech industries, however......, the influence of human capital on the development of low-tech industries is yet to be analysed. This paper provides such an examination of low-tech industries based on an analysis of employment data within manufacturing industries in Denmark in the period 1993–2006. The findings highlight, first, that human...

  8. Characterization of the regulatory region of the zebrafish Prep1.1 gene: analogies to the promoter of the human PREP1.

    Directory of Open Access Journals (Sweden)

    Elisa Bernardi

    Full Text Available Prep1 is a developmentally essential TALE class homeodomain transcription factor. In zebrafish and mouse, Prep1 is already ubiquitously expressed at the earliest stages of development, with important tissue-specific peculiarities. The Prep1 gene in mouse is developmentally essential and has haploinsufficient tumor suppressor activity [1]. We have determined the human Prep1 transcription start site (TSS by primer extension analysis and identified, within 20 bp, the transcription start region (TSR of the zebrafish Prep1.1 promoter. The functions of the zebrafish 5' upstream sequences were analyzed both by transient transfections in Hela Cells and by injection in zebrafish embryos. This analysis revealed a complex promoter with regulatory sequences extending up to -1.8, possibly -5.0 Kb, responsible for tissue specific expression. Moreover, the first intron contains a conserved tissue-specific enhancer both in zebrafish and in human cells. Finally, a two nucleotides mutation of an EGR-1 site, conserved in all species including human and zebrafish and located at a short distance from the TSS, destroyed the promoter activity of the -5.0 Kb promoter. A transgenic fish expressing GFP under the -1.8 Kb zebrafish promoter/enhancer co-expressed GFP and endogenous Prep1.1 during embryonic development. In the adult fish, GFP was expressed in hematopoietic regions like the kidney, in agreement with the essential function of Prep1 in mouse hematopoiesis. Sequence comparison showed conservation from man to fish of the sequences around the TSS, within the first intron enhancer. Moreover, about 40% of the sequences spread throughout the 5 Kbof the zebrafish promoter are concentrated in the -3 to -5 Kb of the human upstream region.

  9. NASA Tech Briefs, February 2009

    Science.gov (United States)

    2009-01-01

    Tech Briefs are short announcements of innovations originating from research and development activities of the National Aeronautics and Space Administration. They emphasize information considered likely to be transferable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. Topics covered include: Measuring Low Concentrations of Liquid Water in Soil; The Mars Science Laboratory Touchdown Test Facility; Non-Contact Measurement of Density and Thickness Variation in Dielectric Materials; Compact Microwave Fourier Spectrum Analyzer; InP Heterojunction Bipolar Transistor Amplifiers to 255 GHz; Combinatorial Generation of Test Suites; In-Phase Power-Combined Frequency Tripler at 300 GHz; Electronic System for Preventing Airport Runway Incursions; Smaller but Fully Functional Backshell for Cable Connector; Glove-Box or Desktop Virtual-Reality System; Composite Layer Manufacturing with Fewer Interruptions; Improved Photoresist Coating for Making CNT Field Emitters; A Simplified Diagnostic Method for Elastomer Bond Durability; Complex Multifunctional Polymer/Carbon-Nanotube Composites; Very High Output Thermoelectric Devices Based on ITO Nanocomposites; Reducing Unsteady Loads on a Piggyback Miniature Submarine; Ultrasonic/Sonic Anchor; Grooved Fuel Rings for Nuclear Thermal Rocket Engines; Pulsed Operation of an Ion Accelerator; Autonomous Instrument Placement for Mars Exploration Rovers; Mission and Assets Database; TCP/IP Interface for the Satellite Orbit Analysis Program (SOAP); Trajectory Calculator for Finite-Radius Cutter on a Lathe; Integrated System Health Management Development Toolkit.

  10. Explaining the Efficacy of Pre-exposure Prophylaxis (PrEP) for HIV Prevention: A Qualitative Study of Message Framing and Messaging Preferences Among US Men Who have Sex with Men.

    Science.gov (United States)

    Underhill, Kristen; Morrow, Kathleen M; Colleran, Christopher; Calabrese, Sarah K; Operario, Don; Salovey, Peter; Mayer, Kenneth H

    2016-07-01

    We investigated message comprehension and message framing preferences for communicating about PrEP efficacy with US MSM. We conducted eight focus groups (n = 38) and n = 56 individual interviews with MSM in Providence, RI. Facilitators probed comprehension, credibility, and acceptability of efficacy messages, including percentages, non-numerical paraphrases, efficacy ranges versus point estimates, and success- versus failure-framed messages. Our findings indicated a range of comprehension and operational understandings of efficacy messages. Participants tended to prefer percentage-based and success-framed messages, although preferences varied for communicating about efficacy using a single percentage versus a range. Participants reported uncertainty about how to interpret numerical estimates, and many questioned whether trial results would predict personal effectiveness. These results suggest that providers and researchers implementing PrEP may face challenges in communicating with users about efficacy. Efforts to educate MSM about PrEP should incorporate percentage-based information, and message framing decisions may influence message credibility and overall PrEP acceptability.

  11. Evaluating the effectiveness of PrepSTART for promoting oral language and emergent literacy skills in disadvantaged preparatory students.

    Science.gov (United States)

    Lennox, Maria; Westerveld, Marleen F; Trembath, David

    2016-09-19

    This study examined the effectiveness of a classroom-based intervention programme aimed at improving the oral language and emergent literacy skills of students from low socio-economic, culturally diverse backgrounds within their first formal year of schooling ("prep"). Data from 137 students were available for analysis. Participants were from three primary schools located in Queensland, Australia. Eight classes were allocated to intervention and two classes acted as a business as usual control. All students received literacy instruction as per the Australian Curriculum. However, the intervention group received 24 weeks of scripted, classroom-based, book-based intervention targeting code- and meaning-related emergent literacy skills. All students were assessed individually pre- and post-intervention on code-related measures (i.e. letter identification and phonological awareness) and meaning-related measures (i.e. vocabulary, oral narrative comprehension and retell). All students made significant improvement over time for all measures. Students in the intervention group showed significantly more progress than the business as usual group on all measures, except for letter identification and oral narrative comprehension. This classroom-based book-based intervention can improve the code- and meaning-related emergent literacy skills of prep students from low socio-economic backgrounds and provide these students with the building blocks for successful literacy acquisition.

  12. SKILL PREP Program for American Indian Students. Final report, 1994

    Energy Technology Data Exchange (ETDEWEB)

    McCulloh, S.; Huebner, P.

    1995-10-01

    The Scientific Knowledge for Indian Learning and Leadership (SKILL) precollege college program of the South Dakota School of Mines and Technology concluded the 1994 PREP program on July 22, 1994. The program graduated 22 students from the 4-week residential math/science program for American Indian students. Primary academic focus was physics (30 hours); each student was given a bicycle to solve problems on angular momentum and mechanical advantage. Mathematical calculations and problem solving exercises were done in mathematics class (20 hours). Preliminary results in math, physics, and geology show dramatic increases in student achievement over the 4- week period. The program paired every two students with a faculty member or research scientist, and each team completed a research project.

  13. Focusing on the Environment to Improve Youth Participation: Experiences and Perspectives of Occupational Therapists.

    Science.gov (United States)

    Anaby, Dana; Law, Mary; Teplicky, Rachel; Turner, Laura

    2015-10-23

    The environment plays a key role in supporting children's participation and can serve as a focus of intervention. This study aimed to elicit the perceptions and experiences of occupational therapists who had applied the PREP approach--Pathways and Resources for Engagement and Participation. PREP is a novel 12-week intervention for youth with physical disabilities, aimed at improving participation in leisure community-based activities by modifying aspects of the environment. Using a qualitative post-intervention only design, 12 therapists took part in individual semi-structured interviews, in which the therapists reflected on their experience using PREP to enable participation. A thematic analysis was conducted. Four themes emerged from the data; two of which were informative in nature, describing elements of the PREP intervention that target multi-layered composition of the environment and use strategies that involve leveraging resources and problem solving. The two remaining themes were reflective in nature, illustrating a new take on the Occupational Therapy role and re-positioning the concept of participation in therapy practices. Results emphasize aspects of the environment that can serve as effective targets of intervention, guided by the PREP approach. Findings can broaden the scope and focus of occupational therapy practice by redefining views on participation and the environment.

  14. Focusing on the Environment to Improve Youth Participation: Experiences and Perspectives of Occupational Therapists

    Directory of Open Access Journals (Sweden)

    Dana Anaby

    2015-10-01

    Full Text Available The environment plays a key role in supporting children’s participation and can serve as a focus of intervention. This study aimed to elicit the perceptions and experiences of occupational therapists who had applied the PREP approach—Pathways and Resources for Engagement and Participation. PREP is a novel 12-week intervention for youth with physical disabilities, aimed at improving participation in leisure community-based activities by modifying aspects of the environment. Using a qualitative post-intervention only design, 12 therapists took part in individual semi-structured interviews, in which the therapists reflected on their experience using PREP to enable participation. A thematic analysis was conducted. Four themes emerged from the data; two of which were informative in nature, describing elements of the PREP intervention that target multi-layered composition of the environment and use strategies that involve leveraging resources and problem solving. The two remaining themes were reflective in nature, illustrating a new take on the Occupational Therapy role and re-positioning the concept of participation in therapy practices. Results emphasize aspects of the environment that can serve as effective targets of intervention, guided by the PREP approach. Findings can broaden the scope and focus of occupational therapy practice by redefining views on participation and the environment.

  15. The Use of REACT Strategy for the Incorporation of the Context of Physics into the Teaching English to the Physics English Prep Students

    Directory of Open Access Journals (Sweden)

    ALİ SÜKRÜ ÖZBAY

    2015-12-01

    Full Text Available The Use of REACT Strategy for the Incorporation of the Context of Physics into the Teaching English to the Physics English Prep Students Abstract  The present study explores department of Physics prep students’ (department of Physics students attending English preparatory program relative performance in English grammar by the use of contextual learning materials in the actual classroom instruction based on the contextual learning theory. Thus, the purpose of this study is to investigate the effect of teaching grammar in physics context for the physics prep students to increase their interests in learning English. Another primary goal of the study is to evaluate the teaching activities which are developed in accordance with the REACT (relating, experiencing, applying, cooperating and transferring strategy in context based approach. The study was with 25 students of Physics at an English prep-school in Turkey. With the aim of determining the effect of contextual teaching materials, sample lessons based on the contextual knowledge and the target grammar points were made. Following the lessons, a structured interview was delivered to the five of the participants. One result is that the incorporation of REACT strategy into the teaching of English to the Physics students proved to be useful for the learners who took part in the study, adding that relating, experiencing, applying, cooperating and transferring the knowledge respectively helped them use and retain the knowledge far more than the traditional classroom teaching methods in grammar teaching. Another specific outcome of the overall findings is that students were able to establish connections between what they learn and how that knowledge can be utilized in physics, which, in turn, has increased their motivation to a higher level.

  16. Virginia Tech business student and professor selected for GM Sullivan Program

    OpenAIRE

    Ho, Sookhan

    2004-01-01

    A student and a faculty member from Virginia Tech's Pamplin College of Business have been selected to participate in the GM Sullivan Fellowship Program that seeks to promote principles of corporate social responsibility developed by the late Rev. Leon H. Sullivan.

  17. Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.

    Science.gov (United States)

    Oriente, Francesco; Fernandez Diaz, Luis Cesar; Miele, Claudia; Iovino, Salvatore; Mori, Silvia; Diaz, Victor Manuel; Troncone, Giancarlo; Cassese, Angela; Formisano, Pietro; Blasi, Francesco; Beguinot, Francesco

    2008-09-01

    We have examined glucose homeostasis in mice hypomorphic for the homeotic transcription factor gene Prep1. Prep1-hypomorphic (Prep1(i/i)) mice exhibit an absolute reduction in circulating insulin levels but normal glucose tolerance. In addition, these mice exhibit protection from streptozotocin-induced diabetes and enhanced insulin sensitivity with improved glucose uptake and insulin-dependent glucose disposal by skeletal muscle. This muscle phenotype does not depend on reduced expression of the known Prep1 transcription partner, Pbx1. Instead, in Prep1(i/i) muscle, we find normal Pbx1 but reduced levels of the recently identified novel Prep1 interactor p160. Consistent with this reduction, we find a muscle-selective increase in mRNA and protein levels of PGC-1alpha, accompanied by enhanced expression of the GLUT4 transporter, responsible for insulin-stimulated glucose uptake in muscle. Indeed, using L6 skeletal muscle cells, we induced the opposite effects by overexpressing Prep1 or p160, but not Pbx1. In vivo skeletal muscle delivery of p160 cDNA in Prep1(i/i) mice also reverses the molecular phenotype. Finally, we show that Prep1 controls the stability of the p160 protein. We conclude that Prep1 controls insulin sensitivity through the p160-GLUT4 pathway.

  18. Efficient endotoxin removal with a new sanitizable affinity column: Affi-Prep Polymyxin.

    Science.gov (United States)

    Talmadge, K W; Siebert, C J

    1989-08-04

    A new affinity column packing for removal of endotoxins has been prepared by coupling USP drug-quality polymyxin B to Affi-Prep, a novel synthetic macroporous polymer. Affi-Prep Polymyxin binds endotoxins from a number of different strains of gram-negative bacteria. Endotoxin binding is not significantly affected by 10 mg/ml of bovine serum albumin or human immunoglobulin G, by 1 mg/ml sodium dodecyl sulphate, or by 1 mg/ml deoxycholate. Affi-Prep Polymyxin is stable to treatment with 1.0 M sodium hydroxide, an important property for sanitizing the resin. The resin shows a high ligand stability, since no leakage of polymyxin B from the packing could be detected. Affi-Prep Polymyxin exhibited the highest endotoxin binding efficiency when compared with several commercial agarose affinity packings.

  19. Preliminary investigation of the advertising and availability of PREPs, the new "safe" tobacco products.

    Science.gov (United States)

    Hickman, Norval; Klonoff, Elizabeth A; Landrine, Hope; Kashima, Kennon; Parekh, Bina; Fernandez, Senaida; Thomas, Kamala; Brouillard, Catherine; Zolezzi, Michele; Jensen, Jennifer; Weslowski, Zorahna

    2004-08-01

    The tobacco industry recently introduced a new set of "safe" cigarettes and nicotine delivery devices that purportedly entail reduced tobacco-related disease risk due to their lower level of some carcinogens and toxins. Little is know about the biological impact of these potential reduced exposure products (PREPs) and nothing is known about their advertising and availability. Hence, two pilot studies were conducted to examine the latter issues for the first time. In Study 1, we examined tobacco ads in 10 popular magazines 1998--2002 and found that only 1% of ads were for PREPs. In Study 2, we attempted to purchase PREPs in a random sample of 113 small stores and found that only 4.4% sold any PREP. These preliminary findings tentatively suggest that the industry might not yet be heavily invested in products that have the potential to increase tobacco use by decreasing its perceived harm. Studies with larger samples are recommended.

  20. Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex.

    Science.gov (United States)

    Mathiasen, Lisa; Bruckmann, Chiara; Pasqualato, Sebastiano; Blasi, Francesco

    2015-01-01

    Human PREP1 and PBX1 are homeodomain transcriptional factors, whose biochemical and structural characterization has not yet been fully described. Expression of full-length recombinant PREP1 (47.6 kDa) and PBX1 (46.6 kDa) in E. coli is difficult because of poor yield, high instability and insufficient purity, in particular for structural studies. We cloned the cDNA of both proteins into a dicistronic vector containing an N-terminal glutathione S-transferase (GST) tag and co-expressed and co-purified a stable PBX1:PREP1 complex. For structural studies, we produced two C-terminally truncated complexes that retain their ability to bind DNA and are more stable than the full-length proteins through various purification steps. Here we report the production of large amounts of soluble and pure recombinant human PBX1:PREP1 complex in an active form capable of binding DNA.

  1. The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration.

    Directory of Open Access Journals (Sweden)

    Daniel A Felix

    2010-04-01

    Full Text Available Planaria continue to blossom as a model system for understanding all aspects of regeneration. They provide an opportunity to understand how the replacement of missing tissues from preexisting adult tissue is orchestrated at the molecular level. When amputated along any plane, planaria are capable of regenerating all missing tissue and rescaling all structures to the new size of the animal. Recently, rapid progress has been made in understanding the developmental pathways that control planarian regeneration. In particular Wnt/beta-catenin signaling is central in promoting posterior fates and inhibiting anterior identity. Currently the mechanisms that actively promote anterior identity remain unknown. Here, Smed-prep, encoding a TALE class homeodomain, is described as the first gene necessary for correct anterior fate and patterning during planarian regeneration. Smed-prep is expressed at high levels in the anterior portion of whole animals, and Smed-prep(RNAi leads to loss of the whole brain during anterior regeneration, but not during lateral regeneration or homeostasis in intact worms. Expression of markers of different anterior fated cells are greatly reduced or lost in Smed-prep(RNAi animals. We find that the ectopic anterior structures induced by abrogation of Wnt signaling also require Smed-prep to form. We use double knockdown experiments with the S. mediterranea ortholog of nou-darake (that when knocked down induces ectopic brain formation to show that Smed-prep defines an anterior fated compartment within which stem cells are permitted to assume brain fate, but is not required directly for this differentiation process. Smed-prep is the first gene clearly implicated as being necessary for promoting anterior fate and the first homeobox gene implicated in establishing positional identity during regeneration. Together our results suggest that Smed-prep is required in stem cell progeny as they form the anterior regenerative blastema and is

  2. The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration.

    Science.gov (United States)

    Felix, Daniel A; Aboobaker, A Aziz

    2010-04-22

    Planaria continue to blossom as a model system for understanding all aspects of regeneration. They provide an opportunity to understand how the replacement of missing tissues from preexisting adult tissue is orchestrated at the molecular level. When amputated along any plane, planaria are capable of regenerating all missing tissue and rescaling all structures to the new size of the animal. Recently, rapid progress has been made in understanding the developmental pathways that control planarian regeneration. In particular Wnt/beta-catenin signaling is central in promoting posterior fates and inhibiting anterior identity. Currently the mechanisms that actively promote anterior identity remain unknown. Here, Smed-prep, encoding a TALE class homeodomain, is described as the first gene necessary for correct anterior fate and patterning during planarian regeneration. Smed-prep is expressed at high levels in the anterior portion of whole animals, and Smed-prep(RNAi) leads to loss of the whole brain during anterior regeneration, but not during lateral regeneration or homeostasis in intact worms. Expression of markers of different anterior fated cells are greatly reduced or lost in Smed-prep(RNAi) animals. We find that the ectopic anterior structures induced by abrogation of Wnt signaling also require Smed-prep to form. We use double knockdown experiments with the S. mediterranea ortholog of nou-darake (that when knocked down induces ectopic brain formation) to show that Smed-prep defines an anterior fated compartment within which stem cells are permitted to assume brain fate, but is not required directly for this differentiation process. Smed-prep is the first gene clearly implicated as being necessary for promoting anterior fate and the first homeobox gene implicated in establishing positional identity during regeneration. Together our results suggest that Smed-prep is required in stem cell progeny as they form the anterior regenerative blastema and is required for

  3. Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.

    Science.gov (United States)

    Longobardi, E; Penkov, D; Mateos, D; De Florian, G; Torres, M; Blasi, Francesco

    2014-01-01

    TALE (three amino acids loop extension) homeodomain transcription factors are required in various steps of embryo development, in many adult physiological functions, and are involved in important pathologies. This review focuses on the PREP, MEIS, and PBX sub-families of TALE factors and aims at giving information on their biochemical properties, i.e., structure, interactors, and interaction surfaces. Members of the three sets of protein form dimers in which the common partner is PBX but they can also directly interact with other proteins forming higher-order complexes, in particular HOX. Finally, recent advances in determining the genome-wide DNA-binding sites of PREP1, MEIS1, and PBX1, and their partial correspondence with the binding sites of some HOX proteins, are reviewed. These studies have generated a few general rules that can be applied to all members of the three gene families. PREP and MEIS recognize slightly different consensus sequences: PREP prefers to bind to promoters and to have PBX as a DNA-binding partner; MEIS prefers HOX as partner, and both PREP and MEIS drive PBX to their own binding sites. This outlines the clear individuality of the PREP and MEIS proteins, the former mostly devoted to basic cellular functions, the latter more to developmental functions.

  4. Preferences for HIV pre-exposure prophylaxis (PrEP) information among men-who-have-sex-with-men (MSM) at community outreach settings

    Science.gov (United States)

    Merchant, Roland C.; Corner, David; Garza, Eduardo; Guan, Wentao; Mayer, Kenneth H.; Brown, Larry; Chan, Philip A

    2016-01-01

    Community outreach efforts to increase HIV pre-exposure prophylaxis (PrEP) utilization by at risk men-who-have-sex-with-men (MSM) first need to elucidate preferences for learning about PrEP and linking to PrEP resources. In this pilot study, we observed that among MSM recruited through community outreach, HIV sexual risk-taking was significant, yet self-perceived PrEP knowledge was low and interest in learning more about PrEP was moderate. Most preferred learning about PrEP and being provided local PrEP clinic information through electronic media. However, receipt of PrEP information alone did not appear to motivate these men into presenting to a local clinic for PrEP evaluation. PMID:27076865

  5. Airport Noise Tech Challenge Overview

    Science.gov (United States)

    Bridges, James

    2011-01-01

    The Supersonics Project, operating under NASA Aeronautics Mission Directorate#s Fundamental Aero Program, has been organized around the Technical Challenges that have historically precluded commercial supersonic flight. One of these Challenges is making aircraft that are capable of such high aerodynamic performance quiet enough around airports that they will not be objectionable. It is recognized that a successful civilian supersonic aircraft will be a system where many new technologies will come together, and for this to happen not only will new low noise propulsion concepts be required, but new engineering tools that predict the noise of the aircraft as these technologies are combined and compromised with the rest of the aircraft design. These are the two main objectives of the Airport Noise Tech Challenge. " ! As a Project in the Fundamental Aero Program, we work at a relatively low level of technology readiness. However, we have high level milestones which force us to integrate our efforts to impact systems-level activities. To keep the low-level work tied to delivering engineering tools and low-noise concepts, we have structured our milestones around development of the concepts and organized our activities around developing and applying our engineering tools to these concepts. The final deliverables in these milestones are noise prediction modules validated against the best embodiment of each concept. These will then be used in cross-disciplinary exercises to demonstrate the viability of aircraft designs to meet all the Technical Challenges. Some of the concepts being developed are shown: Fan Flow Diverters, Multi-jet Shielding, High-Aspect Ratio Embedded Nozzles, Plasma Actuated Instability Manipulation, Highly Variable Cycle Mixer- Ejectors, and Inverted Velocity Profiles. These concepts are being developed for reduced jet noise along with the design tools which describe how they perform when used in various aircraft configurations. Several key upcoming

  6. Interpersonal Communication in High Tech Culture: Eastern or Western?

    Science.gov (United States)

    Isenhart, Myra W.

    1987-01-01

    Investigates interpersonal communication in a high tech organization to test the association between high tech organizations and Western styles of symbolic interaction. Takes a diagnostic, rather than prescriptive, approach to organizational change. (MM)

  7. Standardization and Innovation The 2nd Shenzhen Hi-tech Standardization Forum Held

    Institute of Scientific and Technical Information of China (English)

    Huang Manxue; Huang Li

    2006-01-01

    @@ "The 2nd Shenzhen Hi-tech Standardization Forum"was fulfilled in Shenzhen Civil Center on November 25th,2005. The forum lasted for two days. There were around 400 delegates from enterprises and standardization organizations participating in this forum. Nine experts from standardization, intellectual property organizations and enterprises made their excellent speeches focusing on the topic "Standardardization and Innovation". All participates agreed that standardization improves innovation efficiently.

  8. Theoretical Study of Agricultural High-tech Industrialization

    Institute of Scientific and Technical Information of China (English)

    Jian; XU; Xianming; WU

    2013-01-01

    This paper introduces the characteristics of the agricultural high-tech industries,and points out that the agricultural high-tech industries are intelligence-intensive and knowledge-intensive industries with the characteristics of high investment,high risk,high value-added, which focuses on constant innovation,having strong horizontal and vertical linkages with other enterprises and showing the trend of internationalization.The connotation of agricultural high-tech industrialization is analyzed as follows:Agricultural high-tech industrialization is the process of transformation of the agricultural high-tech achievements to the agricultural high-tech industries; essentially the marketization and commercialization of agricultural high technology; the manifestation of scale and level of agricultural high-tech industries; the manifestation of social impact,social status and social role of agricultural high-tech industries.The development strategies are put forward for agricultural high-tech industrialization:(1) Bringing the research of agricultural high technology into the orbit of the market economy; (2) Implementing the new mechanism to closely link agricultural high technology with modern rural enterprises; (3) Building the agricultural high-tech team with a larger size and high level; (4) Further improving the construction of the agricultural high-tech industrial development zone; (5) Solving the issues concerning agricultural intellectual property and patent; (6) Increasing policy guidance and support efforts for agricultural high-tech industries.

  9. The High-Tech Industry and Its Workers

    Science.gov (United States)

    Kirk, James; Belovics, Robert

    2007-01-01

    The purpose of this article is to provide counselors, academic advisers, and career coaches with a basic understanding of the current state of the high-technology (high-tech) industry in the United States and the people who work in it. A profile of a high-tech worker is presented, several high-tech career developments are described, and selected…

  10. URBox : High tech energy and informal housing

    NARCIS (Netherlands)

    Cuperus, Y.J.; Smets, D.

    2011-01-01

    This paper reports on the URBox concept encompassing the high tech end of solar energy and informal low cost and affordable housing. It aims to contribute to solving the global energy crisis by building solar energy settlements in deserts where land is affordable and sunshine in abundance. First the

  11. Development of High-Tech Skills.

    Science.gov (United States)

    Theuerkauf, Walter E.

    High tech systems not only generate new structures in the production process, but also involve profound changes in job organization, which in turn imply that job qualifications must be modified. In view of the changes within engineering systems and the relevant technologies, it seems expedient to choose a curricular approach based on the concepts…

  12. Virginia Tech opens Engineering Communications Center

    OpenAIRE

    2006-01-01

    In an attempt to provide the engineers of the 21st Century with top-notch professional skills to complement their technical expertise, Virginia Tech, one of ten largest undergraduate engineering programs in the country, has opened an Engineering Communication Center.

  13. URBox : High tech energy and informal housing

    NARCIS (Netherlands)

    Cuperus, Y.J.; Smets, D.

    2011-01-01

    This paper reports on the URBox concept encompassing the high tech end of solar energy and informal low cost and affordable housing. It aims to contribute to solving the global energy crisis by building solar energy settlements in deserts where land is affordable and sunshine in abundance. First the

  14. Senior Military Colleges Meet At Virginia Tech

    OpenAIRE

    Lovegrove, Richard L.

    2003-01-01

    Representatives from the nation's six senior military colleges will hear from the Department of Defense and national Reserve Officer Training Corps (ROTC) commanders during the annual Senior Military Colleges Conference at Virginia Tech on Wednesday and Thursday, Sept. 17 and 18 at the Donaldson Brown Hotel and Conference Center.

  15. Virginia Tech student receives Student Leadership Award

    OpenAIRE

    Dickerson, Susan

    2004-01-01

    The Outstanding Undergraduate Student Leader Award is one of 10 University Student Leadership Awards given annually by Virginia Tech's Department of Student Activities in the Division of Student Affairs to recognize outstanding members, extraordinary achievements by an organization, advisers, volunteerism, and service-learning experiences.

  16. Planning and Designing Today's Career Tech Facility

    Science.gov (United States)

    Seaman, James

    2010-01-01

    During the past 20 years, career and technical education (CTE) has gone through significant changes. CTE has evolved in response to the changes technology has had on the job market. Preparing students for high-tech, high-skill job opportunities is the new focus. The facilities that house these programs, however, have not kept pace with these…

  17. Rethinking HIV prevention to prepare for oral PrEP implementation for young African women

    Directory of Open Access Journals (Sweden)

    Connie L Celum

    2015-07-01

    Full Text Available Introduction: HIV incidence remains high among young women in sub-Saharan Africa in spite of scale-up of HIV testing, behavioural interventions, antiretroviral treatment and medical male circumcision. There is a critical need to critique past approaches and learn about the most effective implementation of evidence-based HIV prevention strategies, particularly emerging interventions such as pre-exposure prophylaxis (PrEP. Discussion: Women in sub-Saharan Africa are at increased risk of HIV during adolescence and into their 20s, in part due to contextual factors including gender norms and relationship dynamics, and limited access to reproductive and sexual health services. We reviewed behavioural, behavioural economic and biomedical approaches to HIV prevention for young African women, with a particular focus on the barriers, opportunities and implications for implementing PrEP in this group. Behavioural interventions have had limited impact in part due to not effectively addressing the context, broader sexual norms and expectations, and structural factors that increase risk and vulnerability. Of biomedical HIV prevention strategies that have been tested, daily oral PrEP has the greatest evidence for protection, although adherence was low in two placebo-controlled trials in young African women. Given high efficacy and effectiveness in other populations, demonstration projects of open-label PrEP in young African women are needed to determine the most effective delivery models and whether women at substantial risk are motivated and able to use oral PrEP with sufficient adherence to achieve HIV prevention benefits. Conclusions: Social marketing, adherence support and behavioural economic interventions should be evaluated as part of PrEP demonstration projects among young African women in terms of their effectiveness in increasing demand and optimizing uptake and effective use of PrEP. Lessons learned through evaluations of implementation strategies

  18. PrEP for key populations in combination HIV prevention in Nairobi: a mathematical modelling study.

    Science.gov (United States)

    Cremin, Ide; McKinnon, Lyle; Kimani, Joshua; Cherutich, Peter; Gakii, Gloria; Muriuki, Festus; Kripke, Katharine; Hecht, Robert; Kiragu, Michael; Smith, Jennifer; Hinsley, Wes; Gelmon, Lawrence; Hallett, Timothy B

    2017-05-01

    The HIV epidemic in the population of Nairobi as a whole is in decline, but a concentrated sub-epidemic persists in key populations. We aimed to identify an optimal portfolio of interventions to reduce HIV incidence for a given budget and to identify the circumstances in which pre-exposure prophylaxis (PrEP) could be used in Nairobi, Kenya. A mathematical model was developed to represent HIV transmission in specific key populations (female sex workers, male sex workers, and men who have sex with men [MSM]) and among the wider population of Nairobi. The scale-up of existing interventions (condom promotion, antiretroviral therapy, and male circumcision) for key populations and the wider population as have occurred in Nairobi is represented. The model includes a detailed representation of a PrEP intervention and is calibrated to prevalence and incidence estimates specific to key populations and the wider population. In the context of a declining epidemic overall but with a large sub-epidemic in MSM and male sex workers, an optimal prevention portfolio for Nairobi should focus on condom promotion for male sex workers and MSM in particular, followed by improved antiretroviral therapy retention, earlier antiretroviral therapy, and male circumcision as the budget allows. PrEP for male sex workers could enter an optimal portfolio at similar levels of spending to when earlier antiretroviral therapy is included; however, PrEP for MSM and female sex workers would be included only at much higher budgets. If PrEP for male sex workers cost as much as US$500, average annual spending on the interventions modelled would need to be less than $3·27 million for PrEP for male sex workers to be excluded from an optimal portfolio. Estimated costs per infection averted when providing PrEP to all female sex workers regardless of their risk of infection, and to high-risk female sex workers only, are $65 160 (95% credible interval [CrI] $43 520-$90 250) and $10 920 (95% CrI $4700

  19. Surveillance indicators for potential reduced exposure products (PREPs: developing survey items to measure awareness

    Directory of Open Access Journals (Sweden)

    McNeill Ann

    2009-10-01

    Full Text Available Abstract Background Over the past decade, tobacco companies have introduced cigarettes and smokeless tobacco products (known as Potential Reduced Exposure Products, PREPs with purportedly lower levels of some toxins than conventional cigarettes and smokeless products. It is essential that public health agencies monitor awareness, interest, use, and perceptions of these products so that their impact on population health can be detected at the earliest stages. Methods This paper reviews and critiques existing strategies for measuring awareness of PREPs from 16 published and unpublished studies. From these measures, we developed new surveillance items and subjected them to two rounds of cognitive testing, a common and accepted method for evaluating questionnaire wording. Results Our review suggests that high levels of awareness of PREPs reported in some studies are likely to be inaccurate. Two likely sources of inaccuracy in awareness measures were identified: 1 the tendency of respondents to misclassify "no additive" and "natural" cigarettes as PREPs and 2 the tendency of respondents to mistakenly report awareness as a result of confusion between PREPs brands and similarly named familiar products, for example, Eclipse chewing gum and Accord automobiles. Conclusion After evaluating new measures with cognitive interviews, we conclude that as of winter 2006, awareness of reduced exposure products among U.S. smokers was likely to be between 1% and 8%, with the higher estimates for some products occurring in test markets. Recommended measurement strategies for future surveys are presented.

  20. Commercial introduction of the Advanced NOxTECH system

    Energy Technology Data Exchange (ETDEWEB)

    Sudduth, B.C. [NOxTECH, Inc., Irvine, CA (United States)

    1997-12-31

    NOxTECH is BACT for diesel electric generators. Emissions of NO{sub x} are reduced 95% or more with substantial concurrent reductions in CO, particulates, and ROG`s. No engine modifications or other exhaust aftertreatments can remove all criteria pollutants as effectively as NOxTECH. The NOxTECH system reliably maintains NH{sub 3} slip below 2 ppm. Unlike other emissions controls, NOxTECH does not generate hazardous by-products. The Advanced NOxTECH system reduces the size, weight, and cost for BACT emissions reductions. Based on the operation of a 150 kW prototype, NOxTECH, Inc. is quoting commercial units for diesel electric generators. Advanced NOxTECH equipment costs about half as much as SCR systems, and NO{sub x} reduction can exceed 95% with guarantees for emissions compliance.

  1. Patterns of Technological Innovation: A Comparative Analysis between Low-tech and High-tech Industries in Brazil

    Directory of Open Access Journals (Sweden)

    Raimundo Eduardo Silveira Fontenele

    2016-06-01

    Full Text Available This paper is intended to contribute to the knowledge about the patterns of innovations in different economic sectors. Hence, the general objective is to assess the differences in rates, directions, sources and efforts of innovations between low-tech and high-tech industries in Brazil. The analysis is based on the database of a survey on innovation (PINTEC conducted by IBGE. The sample includes 8,578 innovative Brazilian companies surveyed from selected low-tech industries (food and textiles manufactures and high-tech industries (vehicles and electronics industries. Descriptive and factorial correspondence analysis were used to identify the variables regarding rates, directions, sources and efforts of innovation that discriminate the low-tech industries of high-tech. The results confirm that low-tech industries differ from high tech ones in all pattern of innovations dimensions analyzed. Hence, low tech industries, compared to high-tech ones, are less innovative, innovate more in process, have fewer people dedicated to R&D, present suppliers as the most significant source of information and is a larger user of Government funding for the purchase of machinery and equipment. On the other hand, the high-tech industries are more innovative, innovate more in products, have more people dedicated to R&D, search for information of other groups of companies, customers and competitors, and their larger use of public financing is for investing in R&D.

  2. Accuracy of reading liquid based cytology slides using the ThinPrep Imager compared with conventional cytology: prospective study

    Science.gov (United States)

    d'Assuncao, Jefferson; Irwig, Les; Macaskill, Petra; Chan, Siew F; Richards, Adele; Farnsworth, Annabelle

    2007-01-01

    Objective To compare the accuracy of liquid based cytology using the computerised ThinPrep Imager with that of manually read conventional cytology. Design Prospective study. Setting Pathology laboratory in Sydney, Australia. Participants 55 164 split sample pairs (liquid based sample collected after conventional sample from one collection) from consecutive samples of women choosing both types of cytology and whose specimens were examined between August 2004 and June 2005. Main outcome measures Primary outcome was accuracy of slides for detecting squamous lesions. Secondary outcomes were rate of unsatisfactory slides, distribution of squamous cytological classifications, and accuracy of detecting glandular lesions. Results Fewer unsatisfactory slides were found for imager read cytology than for conventional cytology (1.8% v 3.1%; Pcytology (7.4% v 6.0% overall and 2.8% v 2.2% for cervical intraepithelial neoplasia of grade 1 or higher). Among 550 patients in whom imager read cytology was cervical intraepithelial neoplasia grade 1 or higher and conventional cytology was less severe than grade 1, 133 of 380 biopsy samples taken were high grade histology. Among 294 patients in whom imager read cytology was less severe than cervical intraepithelial neoplasia grade 1 and conventional cytology was grade 1 or higher, 62 of 210 biopsy samples taken were high grade histology. Imager read cytology therefore detected 71 more cases of high grade histology than did conventional cytology, resulting from 170 more biopsies. Similar results were found when one pathologist reread the slides, masked to cytology results. Conclusion The ThinPrep Imager detects 1.29 more cases of histological high grade squamous disease per 1000 women screened than conventional cytology, with cervical intraepithelial neoplasia grade 1 as the threshold for referral to colposcopy. More imager read slides than conventional slides were satisfactory for examination and more contained low grade cytological

  3. PREP-kurser for soldater, veteraner og deres partnere - en procesevaluering

    DEFF Research Database (Denmark)

    Pollmann, Jeanette Bonde; Hartmann-Madsen, Anne; Vedtofte, Mia Sadowa

    2016-01-01

    Formålet med procesevalueringen er at evaluere, hvordan implementeringen af initiativet PREP-kurser for soldater, veteraner og deres partnere er forløbet. PREP-kurserne tilbydes gratis i en projektperiode fra 2015-2017 i anerkendelsen af at udsendelser kan påvirke parforholdet og kommunikationen...... at evalueringsprocessen er hensigtsmæssig. Det kan ud fra procesevalueringen konkluderes at PREP for soldater, veteraner og deres partnere er blevet implementeret med succes, men at det bør sikres at rapportens anbefalinger implementeres. Vi anbefaler på baggrund af ovenstående at dette initiativ gøres til et permanent...... tilbud for soldater, veteraner og deres pårørende....

  4. Influence of Processing Parameters on Granularity Distribution of Superalloy Powders during PREP

    Institute of Scientific and Technical Information of China (English)

    Huanming CHEN; Benfu HU; Yiwen ZHANG; Huiying LI; Quanmao YU

    2003-01-01

    In order to investigate the influence of processing parameters on the granularity distribution of superalloy powders during the atomization of plasma rotating electrode processing (PREP), in this paper FGH95 superalloy powders is prepared under different processing conditions by PREP and the influence of PREP processing parameters on the granularity distribution of FGH95 superalloy powders is discussed based on fractal geometry theory. The results show that with the increase of rotating velocity of the self-consuming electrode, the fractal dimension of the granularity distribution increases linearly, which results in the increase of the proportion of smaller powders. The change of interval between plasma gun and the self-consuming electrode has a little effect on the granularity distribution, also the fractal dimension of the granularity distribution changed a little correspondingly.

  5. Potential Interventions to Support Adherence to HIV Preexposure Prophylaxis (PrEP): A Systematic Review

    Science.gov (United States)

    Marcus, Julia L.; Buisker, Timothy; Horvath, Tara; Amico, K. Rivet; Fuchs, Jonathan D.; Buchbinder, Susan P.; Grant, Robert M.; Liu, Albert Y.

    2014-01-01

    Objectives Adherence is critical for maximizing the effectiveness of preexposure prophylaxis (PrEP) in preventing HIV infection. Strategies for promoting adherence to HIV treatment, and their potential application to PrEP adherence, have received considerable attention. However, adherence promotion strategies for prevention medications have not been well characterized and may be more applicable to PrEP. We aimed to identify adherence support interventions that have been effective in other prevention fields and could be applied in the HIV prevention context to support pill taking among PrEP users. Methods To identify adherence support interventions that could be evaluated and applied in the PrEP context, we conducted a systematic review across the following prevention fields: hypertension, latent tuberculosis infection, hyperlipidemia, oral contraceptives, osteoporosis, malaria prophylaxis, and post-exposure prophylaxis for HIV infection. We included randomized controlled trials that evaluated the efficacy of interventions to improve adherence to daily oral medications prescribed for primary prevention in healthy individuals or for secondary prevention in asymptomatic individuals. Results Our searches identified 585 studies, of which 48 studies met the eligibility criteria and were included in the review; nine evaluated multiple strategies, yielding 64 separately tested interventions. Interventions with the strongest evidence for improving adherence included complex, resource-intensive interventions, which combined multiple adherence support approaches, and low-cost, low-intensity interventions that provided education or telephone calls for adherence support. Conclusions Our review identified adherence interventions with strong evidence of efficacy across prevention fields and provides recommendations for evaluating these interventions in upcoming PrEP studies. PMID:24580813

  6. Differentiating Criteria for High-Tech Companies

    Directory of Open Access Journals (Sweden)

    Rostek Katarzyna

    2014-12-01

    Full Text Available Manufacturing companies operating within the high-technology sector are of interest to science, industry and national authorities because of the special economic importance attached to them. However, in order to investigate the condition of those companies, support their growth and monitor the effects of the aid awarded to them, it is first necessary to properly identify the business entities belonging to that sector. To identify the entities belonging to the high-technology industry, it is necessary to perform a sequence of activities which form the procedural algorithm. Usefulness of the algorithm has been verified using the example of a group of Warsaw high-tech companies which were subject to investigation under the European project Warsaw Entrepreneurship Forum. The algorithm could be used as the basis for the implementation of an IT tool for the identification and description of high-tech businesses.

  7. Hi tech microeconomics and information nonintensive calculi

    Directory of Open Access Journals (Sweden)

    Mirko Dohnal

    2013-11-01

    Full Text Available The article establishes link between the contributions made to the study of hi tech phenomena. It analyzes the evolution undergone by studies on the topic of the knowledge economics (HI-TECH process carried out by different disciplines (hard and soft sciences – sociology, ecology etc. from the point of view of the objectives they pursue. The attentions are concentrated on analysis of applicable mathematical tools used to develop realistic formal models. Information intensity is defined as the amount of information which is needed for the realistic application of a corresponding formal tool. High information intensity is desirable because it influences the model accuracy. Low information intensity is preferred when high information intensity requires more information items than are available and this is usually the case in knowledge engineering. Fuzzy models seem to be a useful extension of formal tool used in hi tech microeconomics. However, even fuzzy sets could be prohibitively information intensive. Therefore the range of available formal tools must be considerably broader. This paper introduces qualitative and semiqualitative models and rough sets. Each formal tool is briefly characterized.

  8. Attitudes Towards PrEP and Anticipated Condom Use Among Concordant HIV-Negative and HIV-Discordant Male Couples.

    Science.gov (United States)

    Hoff, Colleen C; Chakravarty, Deepalika; Bircher, Anja E; Campbell, Chadwick K; Grisham, Kirk; Neilands, Torsten B; Wilson, Patrick A; Dworkin, Shari

    2015-07-01

    Since the July 2012 approval by the FDA of emtricitabine/ tenofovir disoproxil fumarate (Truvada) for use as pre-exposure prophylaxis (PrEP) against HIV, its feasibility and acceptability has been under study. HIV-discordant couples are likely targets for PrEP but little is known about how this new prevention tool impacts relationships. We examined, among gay male couples, the acceptability of individual and partner use of PrEP and intentions to use condoms with primary and outside partners in the context of PrEP use. Data are from two independent samples of couples recruited in the San Francisco bay area and New York City-a qualitative one (N=48 couples) between March and November, 2011, and a quantitative one (N=171 couples) between June, 2012 and May, 2013. Data were categorized by couple HIV status and general linear models; chi-square tests of independence were used to examine condom-use intentions with primary and outside partners, by sexual risk profile, and race. Almost half of the HIV-negative couples felt PrEP was a good HIV prevention strategy for themselves and their partner. Over half reported that they would not change their current condom use if they or their partner were taking PrEP. However, approximately 30% of HIV-negative couples reported that they would stop using condoms or use them less with primary and outside partners if they were on PrEP or if their partner was on PrEP. A large percentage of couples view PrEP positively. However, to ensure safety for both partners, future programing must consider those who intend not to use condoms while on PrEP.

  9. The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices

    Directory of Open Access Journals (Sweden)

    Jae M Sevelius

    2016-10-01

    Full Text Available Introduction: Globally, transgender (“trans” women are one of the key populations most disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP is the newest and most promising biomedical HIV prevention intervention to date. This paper reviews relevant literature to describe the current state of the science and describes the potential role of PrEP among trans women, including a discussion of unique considerations for maximizing the impact of PrEP for this vulnerable population. Methods: Available information, including but not limited to existing scientific literature, about trans women and PrEP was reviewed and critiqued based on author expertise, including PrEP clinical trials and rollout. Results: To date, PrEP demonstration projects and clinical trials have largely excluded trans women, or have not included them in a meaningful way. Data collection strategies that fail to identify trans women in clinical trials and research further limit the ability to draw conclusions about trans women's unique needs and devise strategies to meet them. Gender-affirming providers and clinic environments are essential components of any sexual health programme that aims to serve trans women, as they will largely avoid settings that may result in stigmatizing encounters and threats to their identities. While there is currently no evidence to suggest drug-drug interactions between PrEP and commonly used feminizing hormone regimens, community concerns about potential interactions may limit interest in and uptake of PrEP among trans women. Conclusions: In scaling up PrEP for trans women, it is essential to engage trans communities, utilize trans-inclusive research and marketing strategies and identify and/or train healthcare providers to provide gender-affirming healthcare to trans women, including transition-related care such as hormone provision. PrEP implementation guidelines must consider and address trans women's unique barriers and facilitators

  10. The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices

    Science.gov (United States)

    Sevelius, Jae M; Deutsch, Madeline B; Grant, Robert

    2016-01-01

    Introduction Globally, transgender (“trans”) women are one of the key populations most disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is the newest and most promising biomedical HIV prevention intervention to date. This paper reviews relevant literature to describe the current state of the science and describes the potential role of PrEP among trans women, including a discussion of unique considerations for maximizing the impact of PrEP for this vulnerable population. Methods Available information, including but not limited to existing scientific literature, about trans women and PrEP was reviewed and critiqued based on author expertise, including PrEP clinical trials and rollout. Results To date, PrEP demonstration projects and clinical trials have largely excluded trans women, or have not included them in a meaningful way. Data collection strategies that fail to identify trans women in clinical trials and research further limit the ability to draw conclusions about trans women's unique needs and devise strategies to meet them. Gender-affirming providers and clinic environments are essential components of any sexual health programme that aims to serve trans women, as they will largely avoid settings that may result in stigmatizing encounters and threats to their identities. While there is currently no evidence to suggest drug-drug interactions between PrEP and commonly used feminizing hormone regimens, community concerns about potential interactions may limit interest in and uptake of PrEP among trans women. Conclusions In scaling up PrEP for trans women, it is essential to engage trans communities, utilize trans-inclusive research and marketing strategies and identify and/or train healthcare providers to provide gender-affirming healthcare to trans women, including transition-related care such as hormone provision. PrEP implementation guidelines must consider and address trans women's unique barriers and facilitators to uptake and

  11. NASA Tech Briefs, January 2011

    Science.gov (United States)

    2011-01-01

    The topics include: 1) Distributed Aerodynamic Sensing and Processing Toolbox; 2) Collaborative Supervised Learning for Sensor Networks; 3) Hazard Detection Software for Lunar Landing; 4) Onboard Nonlinear Engine Sensor and Component Fault Diagnosis and Isolation Scheme; 5) Network-Capable Application Process and Wireless Intelligent Sensors for ISHM; 6) Interface Supports Multiple Broadcast Transceivers for Flight Applications; 7) FPGA Sequencer for Radar Altimeter Applications; 8) Miniature Sapphire Acoustic Resonator - MSAR; 9) Process-Hardened, Multi-Analyte Sensor for Characterizing Rocket Plume Constituents; 10) SAD5 Stereo Correlation Line-Striping in an FPGA; 11) Hybrid Composite Cryogenic Tank Structure; 12) Nanoscale Deformable Optics; 13) Reliability-Based Design Optimization of a Composite Airframe Component; 14) Zinc Oxide Nanowire Interphase for Enhanced Lightweight Polymer Fiber Composites; 15) Plasma Igniter for Reliable Ignition of Combustion in Rocket Engines; 16) Wire Test Grip Fixture; 17) A Sub-Hertz, Low-Frequency Vibration Isolation Platform; 18) Carbon Nanofibers Synthesized on Selective Substrates for Nonvolatile Memory and 3D Electronics; 19) Nanoparticle/Polymer Nanocomposite Bond Coat or Coating; 20) High-Resolution Wind Measurements for Offshore Wind Energy Development; 21) Spring Tire; 22) Marsviewer 2008; 23) Mission Services Evolution Center Message Bus; 24) Major Constituents Analysis for the Vehicle Cabin Atmosphere Monitor; 25) Astronaut Health Participant Summary Application; 26) Adaption of the AMDIS Method to Flight Status on the VCAM Instrument; 27) Natural Language Interface for Safety Certification of Safety-Critical Software; 28) Cryogenic Caging for Science Instrumentation; 29) Wide-Range Neutron Detector for Space Nuclear Applications; 30) In Situ Guided Wave Structural Health Monitoring System; 31) Multiplexed Energy Coupler for Rotating Equipment; 32) Attitude Estimation in Fractionated Spacecraft Cluster Systems; 33

  12. Including an Exam P/1 Prep Course in a Growing Actuarial Science Program

    Science.gov (United States)

    Wakefield, Thomas P.

    2014-01-01

    The purpose of this article is to describe the actuarial science program at our university and the development of a course to enhance students' problem solving skills while preparing them for Exam P/1 of the Society of Actuaries (SOA) and the Casualty Actuary Society (CAS). The Exam P/1 prep course, formally titled Mathematical Foundations of…

  13. Including an Exam P/1 Prep Course in a Growing Actuarial Science Program

    Science.gov (United States)

    Wakefield, Thomas P.

    2014-01-01

    The purpose of this article is to describe the actuarial science program at our university and the development of a course to enhance students' problem solving skills while preparing them for Exam P/1 of the Society of Actuaries (SOA) and the Casualty Actuary Society (CAS). The Exam P/1 prep course, formally titled Mathematical Foundations of…

  14. Quality improvement: single-field sterile scrub, prep, and dwell for laparoscopic hysterectomy.

    Science.gov (United States)

    O'Hanlan, Katherine A; McCutcheon, Stacey Paris; McCutcheon, John G; Charvonia, Beth E

    2013-05-01

    The vulva and vaginal interior are considered a contaminated surgical area, and current OR guidelines require surgeons who are gloved and gowned at the abdominal field to avoid contact with the urethral catheter, the uterine manipulator, and the introitus or to change their gloves and even regown if contact occurs. It is our belief that the perception of the vaginal field as contaminated reflects a lack of specific standards for the preoperative cleansing of the deeper vagina and a lack of preoperative prep instructions for the combined fields. We developed a comprehensive single-field prep technique designed to improve surgical efficiency and prevent contamination of the sterile field. Combining a methodical scrub, prep, and dwell, this technique allows the entire abdomino-perineovaginal field to be treated as a single sterile field for laparoscopic procedures. Our surgical site infection rate of 1.8% when using this single-field prep technique and the subsequent surgical treatment of the abdominal, vaginal, and perineal fields as a single sterile field is well within reported norms.

  15. Moving beyond Test-Prep Pedagogy: Dialoguing with Multicultural Preservice Teachers for a Quality Education

    Science.gov (United States)

    Rodríguez, Louie F.

    2013-01-01

    In a "post-NCLB era," the schooling experiences of mostly low-income students of color continue to be consumed by a test-prep pedagogy--narrowed curriculum, low expectations, and ignored relationships. In this article the author describes a pedagogical approach using educational dialogues to engage preservice teachers to critically…

  16. High Energy Physics Research at Louisiana Tech

    Energy Technology Data Exchange (ETDEWEB)

    Sawyer, Lee [Louisiana State Univ., Baton Rouge, LA (United States); Greenwood, Zeno [Louisiana State Univ., Baton Rouge, LA (United States); Wobisch, Marcus [Louisiana State Univ., Baton Rouge, LA (United States)

    2013-06-28

    The goal of this project was to create, maintain, and strengthen a world-class, nationally and internationally recognized experimental high energy physics group at Louisiana Tech University, focusing on research at the energy frontier of collider-based particle physics, first on the DØ experiment and then with the ATLAS experiment, and providing leadership within the US high energy physics community in the areas of jet physics, top quark and charged Higgs decays involving tau leptons, as well as developing leadership in high performance computing.

  17. AARP iPad Tech to Connect

    CERN Document Server

    Boyd, Barbara

    2012-01-01

    The world is at your fingertips with iPad! AARP iPad: Tech to Connect introduces you to the world?s most popular tablet device, the iPad, and all the amazing things it has to offer. In clear, non-technical language, this book guides you through registering and setting up your iPad, getting acquainted with the multitouch interface, navigating around the screen, finding and downloading apps, reading books, listening to music, watching videos, surfing the web, and communicating with friends and family. Developed in partnership with AARP and dedicated to helping readers stay connected with friends

  18. Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America

    Science.gov (United States)

    Ravasi, Giovanni; Grinsztejn, Beatriz; Baruch, Ricardo; Guanira, Juan Vicente; Luque, Ricardo; Cáceres, Carlos F; Ghidinelli, Massimo

    2016-01-01

    Introduction Despite progress in scaling up antiretroviral treatment, HIV prevention strategies have not been successful in significantly curbing HIV incidence in Latin America. HIV prevention interventions need to be expanded to target the most affected key populations with a combination approach, including new high impact technologies. Oral pre-exposure prophylaxis (PrEP) is recommended as additional prevention choice for individuals at higher risk of infection and could become a cost-effective prevention tool. We discuss the barriers and solutions for a fair consideration of PrEP as part of combination HIV prevention strategies in Latin America. Discussion Although demonstration projects are ongoing or being planned in a number of countries, to date no Latin American country has implemented a public PrEP programme. The knowledge of policymakers about PrEP implementation needs to be strengthened, and programmatic guidance and cost estimate tools need to be developed to support adequate planning. Despite high levels of awareness among health providers, especially if engaged in HIV or key population care, willingness to prescribe PrEP is still low due to the lack of national policies and guidelines. Key populations, especially men who have sex with men, transgender women and sex workers, have been engaged in demonstration projects, and qualitative research shows high awareness and willingness to use PrEP, especially if accessible in the public sector for free or at affordable price. Concerns of safety, adherence, effectiveness and risk compensation need to be addressed through targeted social communication strategies to improve PrEP knowledge and stimulate demand. Alliance among policymakers, civil society and representatives from key populations, healthcare providers and researchers will be critical for the design and successful implementation of PrEP demonstration projects of locally adapted delivery models. The use of mechanisms of joint negotiation and

  19. Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America

    Directory of Open Access Journals (Sweden)

    Giovanni Ravasi

    2016-10-01

    Full Text Available Introduction: Despite progress in scaling up antiretroviral treatment, HIV prevention strategies have not been successful in significantly curbing HIV incidence in Latin America. HIV prevention interventions need to be expanded to target the most affected key populations with a combination approach, including new high impact technologies. Oral pre-exposure prophylaxis (PrEP is recommended as additional prevention choice for individuals at higher risk of infection and could become a cost-effective prevention tool. We discuss the barriers and solutions for a fair consideration of PrEP as part of combination HIV prevention strategies in Latin America. Discussion: Although demonstration projects are ongoing or being planned in a number of countries, to date no Latin American country has implemented a public PrEP programme. The knowledge of policymakers about PrEP implementation needs to be strengthened, and programmatic guidance and cost estimate tools need to be developed to support adequate planning. Despite high levels of awareness among health providers, especially if engaged in HIV or key population care, willingness to prescribe PrEP is still low due to the lack of national policies and guidelines. Key populations, especially men who have sex with men, transgender women and sex workers, have been engaged in demonstration projects, and qualitative research shows high awareness and willingness to use PrEP, especially if accessible in the public sector for free or at affordable price. Concerns of safety, adherence, effectiveness and risk compensation need to be addressed through targeted social communication strategies to improve PrEP knowledge and stimulate demand. Alliance among policymakers, civil society and representatives from key populations, healthcare providers and researchers will be critical for the design and successful implementation of PrEP demonstration projects of locally adapted delivery models. The use of mechanisms of joint

  20. PREFACE: Modern Technologies in Industrial Engineering (ModTech2015)

    Science.gov (United States)

    Oanta, E.; Comaneci, R.; Carausu, C.; Placzek, M.; Cohal, V.; Topala, P.; Nedelcu, D.

    2015-11-01

    attended by 140 participants from 17 countries. The authors and co-authors were from various countries worldwide, namely: Sweden, China, Switzerland, Romania, Serbia, Germany, Netherlands, Belgium, France, South Korea, Taiwan, Poland, USA, Slovenia, Turkey, Republic of Moldova, Russia, Finland, Japan, Ukraine, Portugal, Uzbekistan, Iraq, Italy and India. The Keynote Speakers were as follows: Prof. Esteban Broitman - Linkoping University, Sweden; Prof. Ziyi Ge - NIMTE, Chinese Academy of Sciences, Ningbo, China; Prof. Thomas Graule - EMPA, Switzerland; prof. Razvan Tamas - Constanta Maritime University, Romania; Prof. Rainer Gadow - University of Stuttgart, Germany; Prof. Marcel Van de Voorde - DELFT University of Technology, Netherlands; Prof. Chris Lacor - Vrije University, Brussels, Belgium; Prof. Fiqiri Hodaj - National Polytechnique Institute of Grenoble, France; Prof. Hong Seok Park - University of Ulsan, South Korea; Prof. Der-Jang Liaw - National Taiwan University of Science and Technology, Taiwan; Prof. Petrica Vizureanu - Gheorghe Asachi Technical University of Iasi, Romania. The main publications of ModTech2015 International Conference are as follows: IOP Conference Series: Materials Science and Engineering, United Kingdom, Indian Journal of Engineering & Materials Sciences (IJEMS) and International Journal of Modern Manufacturing Technologies (IJMMT).

  1. Prevalence of metabolic syndrome and related factors in Taiwanese high-tech industry workers

    Directory of Open Access Journals (Sweden)

    Tzung-Yi Tsai

    2011-01-01

    Full Text Available OBJECTIVES: In light of the increasing number of high-tech industry workers and the differences in their working conditions compared to those of the general population, the health status of these workers merits serious attention. This study aimed to explore the prevalence of metabolic syndrome and its correlates among Taiwanese high-tech industry workers. METHODS: This cross-sectional study included 4,666 workers who participated in labor health examinations at a hospital in southern Taiwan in 2008. Participants with metabolic syndrome were defined using the criteria proposed by the Taiwan National Department of Health in 2007. Factors associated with metabolic syndrome were determined using multiple logistic regression analysis. RESULTS: The overall prevalence of metabolic syndrome was 8.2%, and the prevalence was higher in men than in women (14.0% vs. 2.3%, p<0.01. Male gender, advanced age, elevated white blood count, and elevated levels of blood biochemistry markers, such as alanine aminotransferase and uric acid, can independently predict metabolic syndrome. CONCLUSIONS: The prevalence of metabolic syndrome among high-tech industry workers is lower than in the general population. Our study's findings may facilitate early health assessments and the provision of proper workplace health promotion programs to reduce the risks faced by high-risk workers.

  2. Prevalence of metabolic syndrome and related factors in Taiwanese high-tech industry workers.

    Science.gov (United States)

    Tsai, Tzung-Yi; Cheng, Jung-Feng; Lai, Yu-Min

    2011-01-01

    In light of the increasing number of high-tech industry workers and the differences in their working conditions compared to those of the general population, the health status of these workers merits serious attention. This study aimed to explore the prevalence of metabolic syndrome and its correlates among Taiwanese high-tech industry workers. This cross-sectional study included 4,666 workers who participated in labor health examinations at a hospital in southern Taiwan in 2008. Participants with metabolic syndrome were defined using the criteria proposed by the Taiwan National Department of Health in 2007. Factors associated with metabolic syndrome were determined using multiple logistic regression analysis. The overall prevalence of metabolic syndrome was 8.2%, and the prevalence was higher in men than in women (14.0% vs. 2.3%, phigh-tech industry workers is lower than in the general population. Our study's findings may facilitate early health assessments and the provision of proper workplace health promotion programs to reduce the risks faced by high-risk workers.

  3. TechTrends 2010-2015: A Content Analysis

    Science.gov (United States)

    Stauffer, Eric

    2017-01-01

    This study is a content analysis of articles published within the journal "TechTrends" from 2000 to 2015. The study reveals that the publication "TechTrends" has increased the overall number of peer reviewed original papers over the last 6 years. The author describes the proportion of these original papers per volume and…

  4. Georgia tech catalog of gravitational waveforms

    Science.gov (United States)

    Jani, Karan; Healy, James; Clark, James A.; London, Lionel; Laguna, Pablo; Shoemaker, Deirdre

    2016-10-01

    This paper introduces a catalog of gravitational waveforms from the bank of simulations by the numerical relativity effort at Georgia Tech. Currently, the catalog consists of 452 distinct waveforms from more than 600 binary black hole simulations: 128 of the waveforms are from binaries with black hole spins aligned with the orbital angular momentum, and 324 are from precessing binary black hole systems. The waveforms from binaries with non-spinning black holes have mass-ratios q = m 1/m 2 ≤ 15, and those with precessing, spinning black holes have q ≤ 8. The waveforms expand a moderate number of orbits in the late inspiral, the burst during coalescence, and the ring-down of the final black hole. Examples of waveforms in the catalog matched against the widely used approximate models are presented. In addition, predictions of the mass and spin of the final black hole by phenomenological fits are tested against the results from the simulation bank. The role of the catalog in interpreting the GW150914 event and future massive binary black-hole search in LIGO is discussed. The Georgia Tech catalog is publicly available at einstein.gatech.edu/catalog.

  5. TechEdSat Nano-Satellite Series Fact Sheet

    Science.gov (United States)

    Murbach, Marcus; Martinez, Andres; Guarneros Luna, Ali

    2014-01-01

    TechEdSat-3p is the second generation in the TechEdSat-X series. The TechEdSat Series uses the CubeSat standards established by the California Polytechnic State University Cal Poly), San Luis Obispo. With typical blocks being constructed from 1-unit (1U 10x10x10 cm) increments, the TechEdSat-3p has a 3U volume with a 30 cm length. The project uniquely pairs advanced university students with NASA researchers in a rapid design-to-flight experience lasting 1-2 semesters.The TechEdSat Nano-Satellite Series provides a rapid platform for testing technologies for future NASA Earth and planetary missions, as well as providing students with an early exposure to flight hardware development and management.

  6. Tailored combination prevention packages and PrEP for young key populations

    Directory of Open Access Journals (Sweden)

    Audrey Pettifor

    2015-02-01

    Full Text Available Introduction: Young key populations, defined in this article as men who have sex with men, transgender persons, people who sell sex and people who inject drugs, are at particularly high risk for HIV. Due to the often marginalized and sometimes criminalized status of young people who identify as members of key populations, there is a need for HIV prevention packages that account for the unique and challenging circumstances they face. Pre-exposure prophylaxis (PrEP is likely to become an important element of combination prevention for many young key populations. Objective: In this paper, we discuss important challenges to HIV prevention among young key populations, identify key components of a tailored combination prevention package for this population and examine the role of PrEP in these prevention packages. Methods: We conducted a comprehensive review of the evidence to date on prevention strategies, challenges to prevention and combination prevention packages for young key populations. We focused specifically on the role of PrEP in these prevention packages and on young people under the age of 24, and 18 in particular. Results and discussion: Combination prevention packages that include effective, acceptable and scalable behavioural, structural and biologic interventions are needed for all key populations to prevent new HIV infections. Interventions in these packages should meaningfully involve beneficiaries in the design and implementation of the intervention, and take into account the context in which the intervention is being delivered to thoughtfully address issues of stigma and discrimination. These interventions will likely be most effective if implemented in conjunction with strategies to facilitate an enabling environment, including increasing access to HIV testing and health services for PrEP and other prevention strategies, decriminalizing key populations’ practices, increasing access to prevention and care, reducing stigma and

  7. Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.

    Science.gov (United States)

    Risolino, Maurizio; Mandia, Nadia; Iavarone, Francescopaolo; Dardaei, Leila; Longobardi, Elena; Fernandez, Serena; Talotta, Francesco; Bianchi, Fabrizio; Pisati, Federica; Spaggiari, Lorenzo; Harter, Patrick N; Mittelbronn, Michel; Schulte, Dorothea; Incoronato, Mariarosaria; Di Fiore, Pier Paolo; Blasi, Francesco; Verde, Pasquale

    2014-09-01

    Pre-B-cell leukemia homeobox (Pbx)-regulating protein-1 (Prep1) is a ubiquitous homeoprotein involved in early development, genomic stability, insulin sensitivity, and hematopoiesis. Previously we have shown that Prep1 is a haploinsufficient tumor suppressor that inhibits neoplastic transformation by competing with myeloid ecotropic integration site 1 for binding to the common heterodimeric partner Pbx1. Epithelial-mesenchymal transition (EMT) is controlled by complex networks of proinvasive transcription factors responsive to paracrine factors such as TGF-β. Here we show that, in addition to inhibiting primary tumor growth, PREP1 is a novel EMT inducer and prometastatic transcription factor. In human non-small cell lung cancer (NSCLC) cells, PREP1 overexpression is sufficient to trigger EMT, whereas PREP1 down-regulation inhibits the induction of EMT in response to TGF-β. PREP1 modulates the cellular sensitivity to TGF-β by inducing the small mothers against decapentaplegic homolog 3 (SMAD3) nuclear translocation through mechanisms dependent, at least in part, on PREP1-mediated transactivation of a regulatory element in the SMAD3 first intron. Along with the stabilization and accumulation of PBX1, PREP1 induces the expression of multiple activator protein 1 components including the proinvasive Fos-related antigen 1 (FRA-1) oncoprotein. Both FRA-1 and PBX1 are required for the mesenchymal changes triggered by PREP1 in lung tumor cells. Finally, we show that the PREP1-induced mesenchymal transformation correlates with significantly increased lung colonization by cells overexpressing PREP1. Accordingly, we have detected PREP1 accumulation in a large number of human brain metastases of various solid tumors, including NSCLC. These findings point to a novel role of the PREP1 homeoprotein in the control of the TGF-β pathway, EMT, and metastasis in NSCLC.

  8. Are we PREPared? Quality of information available to patients in the UK about PREP on the internet

    Directory of Open Access Journals (Sweden)

    S Duncan

    2012-11-01

    Full Text Available Professional bodies in the UK (BASHH/BHIVA do not currently recommended pre-exposure prophylaxis (PREP to prevent HIV aquisition for men who have sex with men (MSM [1]. Conversely, although Federal Drug Administration approval is awaited, the Centers for Disease Control (CDC have issued clinicians in the USA with interim guidance to facilitate PREP prescriptions [2]. Increasingly patients search the internet for information on HIV treatment, but disparate international policy can lead to confusing patient messages. This study was conducted to systematically assess the quality of internet information available to patients in the UK about PREP. More than 90% of internet searches in the UK are performed using ‘Google.co.uk’ and ‘Bing’ [3]. Using pre-specified criteria, we reviewed the first 100 hits retrieved from each search engine when the following searches were performed: [“HIV pre-exposure prophylaxis”]; [“HIV PREP”]; [“HIV PREP guidelines”]; [“HIV PREP guidelines UK”]; [“truvada prophylaxis HIV”]. Of 172 unique websites identified, 124 websites were active at the time of the review (July 2012. 33 websites were links to academic journals including commentaries and clinical trials, not intended to specifically provide patient information; 5 were internet portals directing users to alternative sites and 10 websites contained no information about PREP. Of the remaining 76 websites, 28 were written by medical professionals and 48 were written by journalists, where 7/48 (15% were individual blogs. 64/76 (84% contained a definition of PREP; 63/76 (83% discussed the rationale and 58/76 (76% reported efficacy data. Advantages and disadvantages of PREP were presented in 56/76 (74% and 41/76 (54% of websites respectively. Only 21/76 (28% of sites referenced existing national guidelines (CDC/BASHH. A minority of sites described the current clinical practice in the UK (7/76, 9% with an even smaller number presenting the

  9. PREPARATIVE ISOLATION AND PURIFICATION OF CHEMICAL CONSTITUENTS OF BELAMCANDA BY MPLC, HSCCC AND PREP-HPLC

    Science.gov (United States)

    Wang, Xiaohong; Liang, Yong; Peng, Cuilin; Xie, Huichun; Pan, Man; Zhang, Tianyou; Ito, Yoichiro

    2010-01-01

    Combined with medium-pressure liquid chromatography (MPLC) and preparative high-pressure liquid chromatography (Prep-HPLC), high-speed countercurrent chromatography (HSCCC) was successfully applied for separation and purification of isoflavonoids from the extract of belamcanda. HSCCC separation was performed on a two-phase solvent system composed of methyl tert-butyl ether -ethyl acetate - n-butyl alcohol – acetonitrile −0.1% aqueous trifluoroacetic acid at a volume radio of 1:2:1:1:5. Semi-purified peak fractions from HSCCC separation were further purified by Prep-HPLC. Nine well-separated fractions were analyzed by HPLC-UV absorption spectrometry to determine their purities and characterized with ESI-MSn. Except for peaksland VII (unknown) seven compounds were identified as apocynin (peak II), mangiferin (peak III), 7-O-methylmangiferin (peak IV), hispidulin (peak V), 3′-hydroxyltectoridin (peak VI), iristectorin B (peak VII), isoiridin (peak IX). PMID:21552369

  10. Supplier challenges in health tech innovation

    DEFF Research Database (Denmark)

    Rolfstam, Max

    Suppliers, in particular small innovative firms, is an important contributor not only for innovation in health-tech, but also a component to consider in the light of the emerging policy interest for using public procurement as a means to stimulate innovation. Research on barriers preventing...... these firms from providing innovations to public health authorities is therefore easily justified. Although substantive knowledge already prevails on the topic, it appears to be a lack in the literature concerning small innovative firms. To help to overcome this gap the paper discusses preliminary case study...... findings collected in the context of the Baltic Sea Health Region HealthPort project. The overall aim with the project was to facilitate ‘business acceleration’ by providing support, training and bridging innovative SMEs and health care organisations ultimately to strengthen the Baltic Sea Region health...

  11. Swords, Shields, and the Fight for Our Children: Lessons from Urban Prep

    Science.gov (United States)

    King, Tim

    2011-01-01

    The grim statistics are well known, but bear repeating: in Chicago, close to 60% of Black boys do not graduate from high school, and only one in forty receive a bachelor's degree by age 25. In the fall of 2006, Urban Prep Charter Academy for Young Men-Englewood Campus, the nation's first all-male charter public high school, was opened. In 2010 and…

  12. Esthetic Rehabilitation of the Smile with No-Prep Porcelain Laminates and Partial Veneers

    OpenAIRE

    Arcelino Farias-Neto; Edna Maria da Cunha Ferreira Gomes; Alfonso Sánchez-Ayala; Alejandro Sánchez-Ayala; Larissa Soares Reis Vilanova

    2015-01-01

    Rehabilitation of patients with anterior conoid teeth may present a challenge for the clinician, especially when trying to mimic the nature with composite resins. This clinical report exemplifies how a patient with conoid upper lateral incisors was rehabilitated with minimally invasive adhesive restorations. Following diagnostic wax-up and cosmetic mock-up, no-prep veneers and ceramic fragments (partial veneers) were constructed with feldspathic porcelain. This restorative material presents e...

  13. Secrecy, empowerment and protection: positioning PrEP in KwaZulu-Natal, South Africa.

    Science.gov (United States)

    Govender, Eliza; Mansoor, Leila; MacQueen, Kate; Abdool Karim, Quarraisha

    2017-11-01

    The release of World Health Organisation guidelines recommending the prophylactic use of daily Truvada(®) for all populations at high risk of acquiring HIV opens the way for implementation of oral pre-exposure prophylaxis (PrEP). The impact of new prevention technologies is, however, dependent on demand creation strategies such as user awareness, acceptability and access, which in turn are influenced by sociocultural and gender norms. This study was conducted in three locations in KwaZulu-Natal, urban, rural and peri-urban, with six participatory workshops. Knowledge, desirable features of a product and demand positioning for PrEP were assessed using a participatory action media research process which included art-based activities and group discussion using a semi-structured interview schedule. The data were analysed using thematic analysis. The key themes that emerged in relation to product adoption were: ability to maintain secrecy of product use; the need for agency with personal choices around HIV prevention; and an increased desire for HIV protection. Findings reaffirm the influence of user engagement in understanding the sociocultural dynamics that influence demand creation for PrEP adoption.

  14. No association between the PREP gene and lithium responsive bipolar disorder

    Directory of Open Access Journals (Sweden)

    Grof Paul

    2007-02-01

    Full Text Available Abstract Background Bipolar disorder (BD is a major psychiatric condition that commonly requires prophylactic and episodic treatment. Lithium (Li has been used for over 40 years now as an effective prophylactic agent. Response to Li treatment seems to be, at least in part, genetically determined. Although we ignore how Li specifically prevents mood episodes, it has previously been suggested that Li exerts an effect on the phosphoinositide pathway, and more recently, it has been proposed that Li may modulate prolyl endopeptidase (PREP. Methods In this study we carried out an association study looking at the PREP gene, located on ch 6q22. Five intronic single nucleotide polymorphisms (SNP, three coding SNPs and one SNP in the 5' UTR were investigated for their frequency in a BD sample of 180 excellent Li responders, 69 Li nonresponders and 126 controls. Genotyping was carried out using the SNaPshot reaction from Applied Biosystems, which is a modified fluorescent single base pair extension procedure. Results Following correction for multiple testing, no significant genotypic, allelic or estimated haplotypic differences were found between responders and nonresponders or between BD patients and controls. Conclusion PREP is an interesting candidate gene to investigate in genetic studies of BD, but our findings do not support the hypothesis that genetic variation in this gene plays a major role in the etiology of BD or Li response.

  15. METHODS OF EVALUATION OF FINANCIAL EFFICIENCY OF HIGH-TECH PROJECTORIENTED COMPANIES

    Directory of Open Access Journals (Sweden)

    Matyushok V. M.

    2015-05-01

    Full Text Available The subject of the research is a complex of high-tech manufacturing companies integrated and functioning in the form of project-oriented companies that are complex dynamic systems with increased efficiency due to changes in its structure and functions, institutional adaptation or use of project management techniques and optimization. The article reveals peculiarities of assessment methods financial performance knowledge-based project-oriented businesses, the main of which is that companies consider their activities as separate independent projects, which have their cost centers and profit. The author's solution to the problem of choosing the optimal investment project among several possible within the framework of the investment program or portfolio of projects, which can be mutually independent of each other, or mutually interdependent. The aim of the work is to study the possibilities and prospects of organizational and economic mechanisms for the use of project campaign for the effective management of knowledge-based enterprises that will quickly adopt new technologies and create optimal production structure. The results will be useful for the public authorities responsible for the development of high-tech industries as well as public and private companies wishing to profitably participate in the implementation of major innovative projects and programs. In the course of the study suggested methods for evaluating the effectiveness of high-tech project-oriented businesses, allowing them to identify the main advantages and disadvantages in meeting their specific production problems

  16. FinTech – What's in a Name?

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    FinTech, the word which originates from marriage of “finance” and “technology”, designates currently a novel, innovative and emerging field which attracts attention from the publicity. At the moment there is no universal understanding and definition of FinTech in the research, however, the topic is widely addressed by the English- and German-speaking press. In this study we aim to make insights into how the press and other popular media understand and frame FinTech, discussing definitions tha...

  17. Fee-based services in sci-tech libraries

    CERN Document Server

    Mount, Ellis

    2013-01-01

    This timely and important book explores how fee-based services have developed in various types of sci-tech libraries. The authoritative contributors focus on the current changing financial aspects of the sci-tech library operation and clarify for the reader how these changes have brought about conditions in which traditional methods of funding are no longer adequate. What new options are open and how they are best being applied in today's sci-tech libraries is fully and clearly explained and illustrated. Topics explored include cost allocation and cost recovery, fees for computer searching, an

  18. An analisys of consumers’ expenditures on high-tech products

    Directory of Open Access Journals (Sweden)

    Dovleac, L.

    2011-01-01

    Full Text Available High – tech products are gradually adopted by consumers, who become to consider them indispensable. Their acquisition requires each time a pretty significant financial investment and a serious decision with a high perceived risk. In this paper we intend to analyse some financial issues related to high-tech products purchased by consumers from Brasov city in 2009, such as: the amount of money spent on high tech products, the financial sources used, the connections between expenditures and consumer’s characteristics.

  19. China's High-tech Exports: Myth and Reality

    OpenAIRE

    Xing, Yuqing

    2011-01-01

    China’s leading position in high-tech exports is a myth created by outdated trade statistics, which are inconsistent with the trade based on global supply chains. Assembled high-tech products, made with imported key parts and components, accounted for 82% of China’s high-tech exports. Current trade statistics mistakenly credit entire values of these assembled products to China, thus greatly inflate the export value. For instance, in 2009 China’s export in the iPhone amounted US$4.6 billion, o...

  20. FinTech – What's in a Name?

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    FinTech, the word which originates from marriage of “finance” and “technology”, designates currently a novel, innovative and emerging field which attracts attention from the publicity. At the moment there is no universal understanding and definition of FinTech in the research, however, the topic is widely addressed by the English- and German-speaking press. In this study we aim to make insights into how the press and other popular media understand and frame FinTech, discussing definitions tha...

  1. The exploitation of "Exploitation" in the tenofovir prep trial in Cameroon: Lessons learned from media coverage of an HIV prevention trial.

    Science.gov (United States)

    Mack, Natasha; Robinson, Elizabeth T; MacQueen, Kathleen M; Moffett, Jill; Johnson, Laura M

    2010-06-01

    media coverage influences how clinical trials are perceived internationally and in communities where trials occur, affecting recruitment, retention, and political support for research. We conducted a discourse analysis of news coverage from 2004-2005 of a trial in Cameroon on oral PrEP for HIV prevention, to identify messages, communication techniques, and sources of messages that were amplified via media. We identified two parallel discourses: one on ethical concerns about the Cameroon trial, and a second, more general "science exploitation" discourse concerned with the potential for trials with vulnerable participant populations to be conducted unethically, benefiting only wealthy populations. Researchers should overtly address exploitation as an integral, ongoing component of research, particularly where historical or cultural conditions set the stage for controversy to emerge.

  2. Virginia Tech, Sweet Briar College formalize student exchange program

    OpenAIRE

    Owczarski, Mark

    2006-01-01

    Virginia Tech and Sweet Briar College have formalized a student exchange program that will broaden the education opportunities of students, provide a diverse campus environment, and facilitate cooperation and collaboration among student and faculty at each institution.

  3. Lavender Commencement Ceremony to honor LGBT graduates at Virginia Tech

    OpenAIRE

    Shannon, Kelly Baker

    2010-01-01

    The Lesbian, Gay, Bisexual, and Transgender (LGBT) Caucus at Virginia Tech is sponsoring the Second Annual Lavender Commencement Ceremony, which will be held on May 13 at 11 a.m. in the Old Dominion Ballroom of Squires Student Center.

  4. Events Scheduled for Virginia Tech's Black History Month

    OpenAIRE

    Felker, Susan B.

    2004-01-01

    A variety of lectures, discussions, performances and displays will be held during Virginia Tech's observance of Black History Month. Events begin Jan. 19 and run through Feb. 28 and are free an open to the public (except where noted).

  5. The Trail Inventory of Bayou Teche NWR [Cycle 2

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to create a baseline inventory of all non-motorized trails on Bayou Teche National Wildlife Refuge. Trails in this inventory are...

  6. Virginia Tech Horse Judging Team leaves its mark in Texas

    OpenAIRE

    Greiner, Lori A.

    2010-01-01

    The Virginia Tech Horse Judging Team completed a successful spring competition season with a win at the American Paint Horse Association's Spring Intercollegiate Horse Judging Sweepstakes in Fort Worth, Texas.

  7. Virginia Tech remains among best values in public higher education

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Virginia Tech is again ranked among the top public colleges and universities in the nation that offer a high quality educational experience at an affordable price, according to "Kiplinger's Personal Finance" magazine.

  8. Virginia Tech recognized for world-class food science program

    OpenAIRE

    Sutphin, Michael D.

    2010-01-01

    The Institute of Food Technologists (IFT) has reaccredited the undergraduate curriculum of Virginia Tech's Department of Food Science and Technology, reaffirming the department's place as a leader in contributing to food quality, safety, marketability, and availability.

  9. Virginia Tech's Cook Counseling Center receives international counseling accreditation

    OpenAIRE

    DeLauder, Rachel

    2010-01-01

    The Virginia Tech Thomas E. Cook Counseling Center has been accredited by the International Association of Counseling Services, Inc., an organization of United States, Canadian, and Australian counseling agencies based in Alexandria, Va.

  10. Bayou Teche National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Bayou Teche NWR for the next 15 years. This plan outlines the Refuge vision and purpose...

  11. Bayou Teche National Wildlife Refuges Habitat Management Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Bayou Teche NWR Habitat Management Plan provides a long-term vision and specific guidance on managing habitats for the resources of concern at Bayou Sauvage NWR,...

  12. Pricing Policy and Strategies for Consumer High-Tech Products

    Directory of Open Access Journals (Sweden)

    Dovleac, L.

    2014-06-01

    Full Text Available This paper highlights the complex process of price setting for consumer high-tech products. These prices are highly influenced by some external factors from the economic and social environment. The main objective of this paper is to establish the most effective pricing policies and strategies used by high-tech companies of various sizes. Decisions about price fixing for consumer high-technology products are largely influenced by consumer behaviour, too.

  13. Overseas Tech Firms Ramp Up Hiring In Silicon Valley

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Fpr years, U.S.high-tech executives have fretted about the loss of technology jobs to countries such as China and India.But there is a countervailing force: Foreign companies are leaning heavily on engineers they hire in Silicon Valley. Companies from Europe and Asia increasingly are using high-tech teams in the Bay Area to conduct long-range research and help design cutting-edge products for global markets.

  14. Virginia Tech creates Caribbean center for education and research

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    Virginia Tech has established a research, education, and outreach center in the Caribbean that will serve as part of a broad strategy to create international centers of scholarship around the world. The Caribbean Center for Education and Research (CCER) in Punta Cana, on the eastern tip of the Dominican Republic, will allow Virginia Tech faculty to conduct research as well as instruct students on biodiversity, environmental and social sustainability, global issues in natural resources, and ho...

  15. Slow Tech: The Bridge between Computer Ethics and Business Ethics

    OpenAIRE

    Patrignani, Norberto; Whitehouse, Diane

    2014-01-01

    Part 1: Society, Social Responsibility, Ethics and ICT; International audience; This paper addresses the difficult task of implementing the concept of Slow Tech, that is, information and communication technology (ICT) that is good, clean and fair, in a business environment. It investigates the democratic, environmental, and social challenges currently facing ICT vendors. More specifically, it examines the opportunities available for these companies to use Slow Tech as a bridging mechanism bet...

  16. Promoting High-tech Industrialization through Mechanism Innovation

    Institute of Scientific and Technical Information of China (English)

    Guo Haiyan; Zhao Baohua

    2002-01-01

    @@ With the further implementation of the knowledge innovation program (KIP), piloted by the Chinese Academy of Sciences (CAS), encouraging progress has been made in contributing to the development of the country's high-tech industry, and forging S&T cooperation with local governments and industrial sectors. This was revealed at the Second CAS Conference on High-tech Industrialization April 25 - 29 in Shenzhen, Guangdong Province.

  17. Allina Health System's approach to high tech and high touch.

    Science.gov (United States)

    Tam, T A

    1997-01-01

    All health care providers, regardless of their integration status, must meet customer expectations to maintain market share and viability. The balance between high tech and high touch customer interactions is not a fad or trend. For integrated health systems with the full continuum of medical care, additional challenges are presented by the organization's competing health care delivery and financing components. Allina Health System describes its integrated health system approach to satisfying customer high tech and high touch needs.

  18. Advanced Production Technology as the Key to the Qualitative Transformation and Growth of High-Tech Exports in Ukraine until 2030

    Directory of Open Access Journals (Sweden)

    Matyushenko Igor Yu.

    2016-03-01

    Full Text Available The article is concerned with an analysis of the high-tech product export by main producing countries and Ukraine for the period of 2012–2014. A structure mismatch of Ukrainian exports of high-tech products with the corresponding global structure, a catastrophic retardation by contrast to the leading countries in the market of high-tech products, as well as a trend towards widening of this gap in 2012-2014, have been determined. It is proved that any increase or at least preserving the volume of high-tech exports are impossible on the existing industrial base and production technologies. It is displayed that an accumulation of high-tech exports will be possible only with implementation of the prospective production technologies (PPT, based on the own unique scientific-technological groundwork in the next 10–15 years, in view of: transition to the new (projected materials with desired properties; participation in research on mathematic modeling for intelligent production systems, co-working in the international projects of this kind; participation in pilot projects in the ICT industry; developing industrial nanobiotechnology; carrying out space research and developments in the terms of projects of the European Space Agency.

  19. Georgia Tech Catalog of Gravitational Waveforms

    CERN Document Server

    Jani, Karan; Clark, James A; London, Lionel; Laguna, Pablo; Shoemaker, Deirdre

    2016-01-01

    This paper introduces a catalog of gravitational waveforms from the bank of simulations by the numerical relativity effort at Georgia Tech. Currently, the catalog consists of 452 distinct waveforms from more than 600 binary black hole simulations: 128 of the waveforms are from binaries with black hole spins aligned with the orbital angular momentum, and 324 are from precessing binary black hole systems. The waveforms from binaries with non-spinning black holes have mass-ratios $q = m_1/m_2 \\le 15$, and those with precessing, spinning black holes have $q \\le 8$. The waveforms expand a moderate number of orbits in the late inspiral, the burst during coalescence, and the ring-down of the final black hole. Examples of waveforms in the catalog matched against the widely used approximate models are presented. In addition, predictions of the mass and spin of the final black hole by phenomenological fits are tested against the results from the simulation bank. The role of the catalog in interpreting the GW150914 even...

  20. Iterest grows for Dutch mid-tech and low-tech greenhouse technology : A greenhouse to suit all tropical conditions (interview with Anne Elings)

    NARCIS (Netherlands)

    Kierkels, T.; Elings, A.

    2014-01-01

    The Netherlands sets the standard for high-tech greenhouses worldwide. But increasingly suppliers are looking too at possibilities within the mid-tech and even the low-tech market segments. The Dutch government is supporting demonstration projects, for example in Mexico, East Africa and Malaysia. Te

  1. The Process of Retirement Planning Scale (PRePS): development and validation.

    Science.gov (United States)

    Noone, Jack H; Stephens, Christine; Alpass, Fiona

    2010-09-01

    Although a substantial proportion of the western population is approaching retirement age, little is known about how they are preparing for the future. Much attention has been paid to the consumption of educational material and retirement wealth in the present literature, but the process of retirement planning has been ignored. S. L. Friedman and E. K. Scholnick's (1997) theoretical model provided the basis for a comprehensive measure of retirement planning. According to their process theory, individuals develop an understanding of the problem, set goals, make a decision to start preparing, and finally undertake the behaviors needed to fulfill their goals. Fifty-two items were developed to assess each stage of the planning process for financial, health, lifestyle, and psychosocial retirement planning. These were tested on a population sample of 1,449 New Zealanders aged 49-60. Confirmatory factor analysis, bivariate correlations, and hierarchical regression provided support for the valid use of the measure. Necessary antecedents, such as the tendency to look to the future, and locus of control were significantly related to the Process of Retirement Planning Scale (PRePS). The PRePS also outperformed retirement planning measures used in the Health and Retirement Study (F. T. Juster & R. Suzman, 1995) after controlling for socioeconomic and psychological variables. This measure will enable social policy makers to determine which stages of retirement planning require support and intervention. The PRePS will also help to determine which domains of retirement planning predict well-being in later life and the factors which differentiate those who are planning from those who are not.

  2. Fuzzy model investic do High-tech projektů

    Directory of Open Access Journals (Sweden)

    Alžběta Kubíčková

    2013-10-01

    Full Text Available Purpose of the article: Relations among parameters of High-tech projects are very complex, vague, partially inconsistent and multidimensional. Optimal decisions to invest into High-tech companies require top field experts and knowledgeable investors. Therefore the conventional methods of investments analysis are not relevant. Therefore fuzzy logic is introduced. Methodology/methods: A fuzzy knowledge base is a flexible framework for acquisition of vague inconsistent knowledge items which are typical for knowledge economics and consequently for High-tech projects. The pooling of the records and / or observations represents a trade-off between minimal modification of the original data and elimination of inconsistencies among available sets of data. Scientific aim: The paper presents a detailed description of fuzzy model of investment decision making into High-tech firm’s projects. A set of conditional statements was used to formalize the effects of selected variables on investment feasibility of High-tech projects. The main aim is to quantify feasibilities of High-tech projects risk investors make good /not bad decisions. Findings: A set of 50 observations of High-tech companies was transformed into a set of 50 conditional statements using 14 variables. The result is the fuzzy model, which can be used to answer investors’ queries. Two queries are answered and presented in details as an example and as a nucleus of a fuzzy dialogue investor – computer. Conclusions: The main problem is the sparseness of the fuzzy model. Many fuzzy similarities are relatively low and the decision process is therefore often problematic. A much more complex set of variables must be applied to specify the fuzzy model to increase reliability of predictions and decisions.

  3. Oral pre-exposure prophylaxis (PrEP) for prevention of HIV in serodiscordant heterosexual couples in the United States: opportunities and challenges.

    Science.gov (United States)

    McMahon, James M; Myers, Julie E; Kurth, Ann E; Cohen, Stephanie E; Mannheimer, Sharon B; Simmons, Janie; Pouget, Enrique R; Trabold, Nicole; Haberer, Jessica E

    2014-09-01

    Oral HIV pre-exposure prophylaxis (PrEP) is a promising new biomedical prevention approach in which HIV-negative individuals are provided with daily oral antiretroviral medication for the primary prevention of HIV-1. Several clinical trials have demonstrated efficacy of oral PrEP for HIV prevention among groups at high risk for HIV, with adherence closely associated with level of risk reduction. In the United States (US), three groups have been prioritized for initial implementation of PrEP-injection drug users, men who have sex with men at substantial risk for HIV, and HIV-negative partners within serodiscordant heterosexual couples. Numerous demonstration projects involving PrEP implementation among MSM are underway, but relatively little research has been devoted to study PrEP implementation in HIV-serodiscordant heterosexual couples in the US. Such couples face a unique set of challenges to PrEP implementation at the individual, couple, and provider level with regard to PrEP uptake and maintenance, adherence, safety and toxicity, clinical monitoring, and sexual risk behavior. Oral PrEP also provides new opportunities for serodiscordant couples and healthcare providers for primary prevention and reproductive health. This article provides a review of the critical issues, challenges, and opportunities involved in the implementation of oral PrEP among HIV-serodiscordant heterosexual couples in the US.

  4. An Exploratory Investigation of the Promoting Responsibility through Education and Prevention (PREP) after School Program for African American At-Risk Elementary School Students

    Science.gov (United States)

    Sale, Elizabeth; Weil, Virginia; Kryah, Rachel

    2012-01-01

    The promoting responsibility through education and prevention (PREP) program is an after school substance abuse and violence prevention program for at-risk fourth and fifth grade youths in St. Louis, Missouri. Staffed by licensed clinical social workers and professional volunteers, PREP offers cultural cooking classes, yoga, and art as well as…

  5. Numerical analysis on solidification process and heat transfer of FGH95 superalloy droplets during PREP

    Institute of Scientific and Technical Information of China (English)

    Huanming Chen; Benfu Hu; Yiwen Zhang; Quanmao Yu; Huiying Li

    2003-01-01

    In order to understand the relation between microstructure of superalloy powders and its solidification progress, the processing parameters are optimized during plasma rotating electrode processing (PREP). It was predicted from the results that the droplet velocities, droplet temperature, and fractional solidification with flight time about FGH95 superalloy droplet have been carried out based on Newtonian heat transfer formulation coupled with the classical heterogeneous nucleation and the specific solidification process. It has been found that the droplet dynamic and thermal behavior is strongly affected by the distribution of droplet diameters,the proportion of cooling atmosphere, but is relatively unaffected by the droplet superheat.

  6. Alcohol based surgical prep solution and the risk of fire in the operating room: a case report

    Directory of Open Access Journals (Sweden)

    Gupta Rajiv

    2008-04-01

    Full Text Available Abstract A few cases of fire in the operating room are reported in the literature. The factors that may initiate these fires are many and include alcohol based surgical prep solutions, electrosurgical equipment, flammable drapes etc. We are reporting a case of fire in the operating room while operating on a patient with burst fracture C6 vertebra with quadriplegia. The cause of the fire was due to incomplete drying of the covering drapes with an alcohol based surgical prep solution. This paper discusses potential preventive measures to minimize the incidence of fire in the operating room.

  7. Eco prep: the economical preparation of ceramic bodies; Ecoprep: la preparacion rentable de masas ceramicas

    Energy Technology Data Exchange (ETDEWEB)

    Luders, M.; Walter, H. J.; Nold, P.; Lobe, R.; Muller, M.; Gerl, S.

    2012-07-01

    Eco prep (Economic Preparation) is the sustainable technology for preparing ceramic bodies with a minimum consumption of resources. It has a huge impact on the energy balance and eliminates the need for additives to generate a high-quality slip to make granules. In consequence Eco prep delivers a significant reduction in production costs, bringing an investment in this technology to the break-even point after a very short time. Reduction in water consumption and additives and the use of new raw materials are other advantages that impulse the implementation of this production technology, as well as important reduction of CO{sub 2} emissions, contributing to meeting the goals of the Kyoto Protocol. In short: A technology already successfully applied in different industries for decades, that includes a compendium of measures based on saving reductions in a range from 66% (energy, water,) and 100% (additives, deflocculants, etc.) and will mark the future in micro granulation processes also in the ceramic industry. (Author)

  8. The PREP pipeline: standardized preprocessing for large-scale EEG analysis.

    Science.gov (United States)

    Bigdely-Shamlo, Nima; Mullen, Tim; Kothe, Christian; Su, Kyung-Min; Robbins, Kay A

    2015-01-01

    The technology to collect brain imaging and physiological measures has become portable and ubiquitous, opening the possibility of large-scale analysis of real-world human imaging. By its nature, such data is large and complex, making automated processing essential. This paper shows how lack of attention to the very early stages of an EEG preprocessing pipeline can reduce the signal-to-noise ratio and introduce unwanted artifacts into the data, particularly for computations done in single precision. We demonstrate that ordinary average referencing improves the signal-to-noise ratio, but that noisy channels can contaminate the results. We also show that identification of noisy channels depends on the reference and examine the complex interaction of filtering, noisy channel identification, and referencing. We introduce a multi-stage robust referencing scheme to deal with the noisy channel-reference interaction. We propose a standardized early-stage EEG processing pipeline (PREP) and discuss the application of the pipeline to more than 600 EEG datasets. The pipeline includes an automatically generated report for each dataset processed. Users can download the PREP pipeline as a freely available MATLAB library from http://eegstudy.org/prepcode.

  9. Virginia Tech's K-9 unit to receive Kevlar vest from alumni organization

    OpenAIRE

    Dickerson, Susan

    2004-01-01

    Hokie, the Virginia Tech Police Department's German shepherd, will be presented with a custom-fitted Virginia Tech Kevlar bulletproof vest to protect him from all the dangers he faces while performing his daily duties.

  10. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Science.gov (United States)

    2013-03-05

    ... Employment and Training Administration Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service..., 2012, applicable to workers of Verizon Business Networks Services, Inc., Order Management...

  11. Arquitectura low tech. Refugio de emergencia con palets

    OpenAIRE

    Borreguero Sánchez, Laura

    2015-01-01

    Este estudio busca profundizar en una alternativa a la arquitectura actual rescatando materiales y técnicas que han sido utilizadas a lo largo de la historia pero que debido a las nuevas tecnologías se han ido perdiendo. Esta “nueva” forma de construir se conoce como arquitectura Low Tech. Así, Low Tech hace referencia a una arquitectura que no precisa de una gran tecnología y que se sirve de materiales y técnicas propios de cada lugar haciendo de éste un sistema económico e...

  12. Displacement in new economy labor markets: Post-displacement wage loss in high tech versus low tech cities.

    Science.gov (United States)

    Davis, Daniel J; Rubin, Beth A

    2016-11-01

    While scholars and politicians tout education as the salve to employment disruptions, we argue that the geography of the new economy, and the social closure mechanisms that geography creates, may be just as important as individuals' characteristics for predicting post-displacement wage loss (or gain). We use data from the 2012 Displaced Workers ement of the Current Population Survey and from the 2010 United States Census to test hypotheses linking local labor markets in different industrial contexts to post-displacement wage loss. Our results point to age as a closure mechanism, and to the partially protective effect of education in high-tech versus low-tech economic sectors. This study is the first to use national level data to examine how employment in high-tech cities influences post-displacement wages. These findings are relevant both for theorizing about the new economy and for public policy. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Experimental particle physics research at Texas Tech University

    Energy Technology Data Exchange (ETDEWEB)

    Akchurin, Nural [Texas Tech Univ., Lubbock, TX (United States); Lee, Sung-Won [Texas Tech Univ., Lubbock, TX (United States); Volobouev, Igor [Texas Tech Univ., Lubbock, TX (United States); Wigmans, Richard [Texas Tech Univ., Lubbock, TX (United States)

    2016-06-22

    The high energy physics group at Texas Tech University (TTU) concentrates its research efforts on the Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) and on generic detector R&D for future applications. Our research programs have been continuously supported by the US Department of Energy for over two decades, and this final report summarizes our achievements during the last grant period from May 1, 2012 to March 31, 2016. After having completed the Run 1 data analyses from the CMS detector, including the discovery of the Higgs boson in July 2012, we concentrated on commissioning the CMS hadron calorimeter (HCAL) for Run 2, performing analyses of Run 2 data, and making initial studies and plans for the second phase of upgrades in CMS. Our research has primarily focused on searches for Beyond Standard Model (BSM) physics via dijets, monophotons, and monojets. We also made significant contributions to the analyses of the semileptonic Higgs decays and Standard Model (SM) measurements in Run 1. Our work on the operations of the CMS detector, especially the performance monitoring of the HCAL in Run 1, was indispensable to the experiment. Our team members, holding leadership positions in HCAL, have played key roles in the R&D, construction, and commissioning of these detectors in the last decade. We also maintained an active program in jet studies that builds on our expertise in calorimetry and algorithm development. In Run 2, we extended some of our analyses at 8 TeV to 13 TeV, and we also started to investigate new territory, e.g., dark matter searches with unexplored signatures. The objective of dual-readout calorimetry R&D was intended to explore (and, if possible, eliminate) the obstacles that prevent calorimetric detection of hadrons and jets with a comparable level of precision as we have grown accustomed to for electrons and photons. The initial prototype detector was successfully tested at the SPS/CERN in 2003-2004 and evolved over the

  14. 14th High-Tech Plasma Processes Conference (HTPP 14)

    Science.gov (United States)

    2017-04-01

    Preface The High-Tech Plasma Processes Conference (HTPP) is a bi-annual international conference based in Europe with topics encompassing the whole area of plasma processing science. This conference is open to all the international community in the world involved in plasma science and plasma technology. The aim of the conference is to bring different scientific communities together, facilitate the contacts between science, technology and industry and provide a platform for the exploration of both fundamental topics and new applications of plasmas. For this edition of HTPP, as was the case for the last, we have achieved a well balanced participation from the communities of both thermal and non-thermal plasma researchers. 75 people from 17 countries attended the conference with the total number of contributions being 74, consisting of 19 invited talks and 55 poster contributions. As a HTPP tradition a poster competition has been carried out during the conference. The winner of the poster competition was Fabrice Mavier from Université de Limoges, France with his paper “Pulsed arc plasma jet synchronized with drop-on-demand dispenser” All the participants also ejoyed the social program including an “unconventional” tour of the city, the visit to the famous Hofbräuhaus and the dinner at the Blutenburg, a beautiful inner-city castle. We have received papers corresponding to the contributions of HTPP-2014 that have been submitted for publication in this volume of Journal of Physics: Conference Series. Each submitted contribution has been peer reviewed and the Editors are very grateful to the referees for their careful support in improving the original manuscripts. In total, 18 manuscripts have been accepted for publication covering a range of topics of plasma processing science from plasma fundamentals to process applications through to experiments, diagnostics and modelling. We deeply thank the authors for their enthusiastic and high-grade contributions and we

  15. High-tech exports from developing countries: A symptom of technology spurts or statistical illusion?

    OpenAIRE

    Martin Srholec

    2005-01-01

    Specialization in high-tech products is frequently used to capture technology intensity of exports. The literature suggests that developing countries are increasingly becoming exporters of high-tech products, and some may even be among the most deeply specialized countries in the field of high-tech exports. The paper scrutinizes the relevance of the taxonomies that classify exports by technological intensity in this context. It is shown that specialization in high-tech exports typically does ...

  16. Standard Tools for Measuring Post Implementation TECH MOD (Technology Modernization) Cost Savings.

    Science.gov (United States)

    2014-09-26

    Another con- tractor developed a formula based on the Cost Performance Report ( CPR ) which provides unit cost savings. The final contractor measured...DEPARTMENT OF DEFENSE INITIATIVES ........... 2 C. TECH MOD HISTORY ............ ...... ......... 3 D. THE TECH MOD PROCESS ........... ............ 4...Guide 4 Oct 1984). C. TECH MOD HISTORY The first Tech Mod planning started in late 1970 with the F-16 program and the need to improve the government

  17. Tech transfer outreach. An informal proceedings of the first technology transfer/communications conference

    Energy Technology Data Exchange (ETDEWEB)

    Liebetrau, S. [ed.

    1992-10-01

    This document provides an informal summary of the conference workshop sessions. ``Tech Transfer Outreach!`` was originally designed as an opportunity for national laboratory communications and technology transfer staff to become better acquainted and to discuss matters of mutual interest. When DOE field office personnel asked if they could attend, and then when one of our keynote speakers became a participant in the discussions, the actual event grew in importance. The conference participants--the laboratories and DOE representatives from across the nation--worked to brainstorm ideas. Their objective: identify ways to cooperate for effective (and cost-effective) technology transfer outreach. Thus, this proceedings is truly a product of ten national laboratories and DOE, working together. It candidly presents the discussion of issues and the ideas generated by each working group. The issues and recommendations are a consensus of their views.

  18. Cost-effectiveness of PrEP in HIV/AIDS control in Zambia: a stochastic league approach

    NARCIS (Netherlands)

    Nichols, B.E.; Baltussen, R.M.; Dijk, J.H. van; Thuma, P.E.; Nouwen, J.L.; Boucher, C.A.B.; Vijver, D.A. van de

    2014-01-01

    BACKGROUND: Earlier antiretroviral therapy initiation and pre-exposure prophylaxis (PrEP) prevent HIV, although at a substantial cost. We use mathematical modeling to compare the cost-effectiveness and economic affordability of antiretroviral-based prevention strategies in rural Macha, Zambia.

  19. Saying 'No' to PrEP research in Malawi: what constitutes 'failure' in offshored HIV prevention research?

    Science.gov (United States)

    Peterson, Kristin; Folayan, Morenike Oluwatoyin; Chigwedere, Edward; Nthete, Evaristo

    2015-12-01

    Between 2004 and 2005, the first multi-sited clinical trial tested whether an existing, marketed antiretroviral drug, Tenofovir (TDF), could prevent HIV transmission. Referred to as pre-exposure prophylaxis (PrEP), most of these trial sites prematurely closed down. Two sites located in Cambodia and Cameroon received international media attention. But little attention was drawn to sites in Malawi and Nigeria, where university ethicists and research scientists extensively debated PrEP. This article focuses on events that took place in Malawi where there was a prolonged dispute over the scientific rationales of PrEP and not trial specific ethics referred to as 'bioethics'. Specifically, the article discusses debates pertaining to three PrEP trial protocols that were refused ethics approval in Malawi between 2004 and 2009. It is argued that HIV science debates in Malawi are embedded in postcolonial politics--geopolitical histories and state and household economic dispossessions that have created the structural possibilities for Malawi to become an offshore destination for HIV clinical research. As such, ethics in this case does not pertain to trial or bioethical 'failures'. Rather, ethics is located at the scale of imperial relations that give rise to multiple, often invisible, research concerns and constraints.

  20. Spatial Planning and High-tech Development A comparative study of Eindhoven city-region, the Netherlands and Hsinchu City-region, Taiwan

    Directory of Open Access Journals (Sweden)

    Wei-Ju Huang

    2013-08-01

    in the process of high-tech spatial development, because they have access to a wide range of know-how and crucial resources. The creation of new institutional arenas to invite institutes and firms to participate in the process of decision-making is a good strategy for governments, although they must assure that the decision-making process is transparent and accountable, and meets the principles of social justice.Finally, the two cases have shown that a successful high-tech spatial development would have spatial effects on the surrounding areas, such as traffic congestion, imbalance between land supply and demand for housing and/or industrial land, and so on. It is necessary to anticipate and monitor continuously the externalities of the development from a more comprehensive perspective and to leave room for adjustment to the spatial planning and governance approaches.The analytical framework built upon the institutional concepts of Ostrom and Scharpf worked well in this research, but in the process of conducting the empirical study I found that the framework of institutional analysis I established for the empirical study implied a temporarily fixed situation for analysis. Such a framework did create an easier situation for analysis, but proved difficult to use to investigate and explain the dynamic interrelationships between the changing institutional contexts and the decision making of high-tech spatial planning at a specific place and time.While considering this limitation, I adopted a diachronic approach to complement the empirical study of part three, in order to understand the influences of prior institutional developments and specific episodes on later policy/decision making and action taking. In the future, if other studies consider applying the frameworks of this research, the effect of historical path dependency has to be taken into consideration.

  1. A qualitative study of provider thoughts on implementing pre-exposure prophylaxis (PrEP in clinical settings to prevent HIV infection.

    Directory of Open Access Journals (Sweden)

    Emily A Arnold

    Full Text Available BACKGROUND: A recent clinical trial demonstrated that a daily dose tenofovir disoproxil fumarate and emtricitabrine (TDF-FTC can reduce HIV acquisition among men who have sex with men (MSM and transgender (TG women by 44%, and up to 90% if taken daily. We explored how medical and service providers understand research results and plan to develop clinical protocols to prescribe, support and monitor adherence for patients on PrEP in the United States. METHODS: Using referrals from our community collaborators and snowball sampling, we recruited 22 healthcare providers in San Francisco, Oakland, and Los Angeles for in-depth interviews from May-December 2011. The providers included primary care physicians seeing high numbers of MSM and TG women, HIV specialists, community health clinic providers, and public health officials. We analyzed interviews thematically to produce recommendations for setting policy around implementing PrEP. Interview topics included: assessing clinician impressions of PrEP and CDC guidance, considerations of cost, office capacity, dosing schedules, and following patients over time. RESULTS: Little or no demand for PrEP from patients was reported at the time of the interviews. Providers did not agree on the most appropriate patients for PrEP and believed that current models of care, which do not involve routine frequent office visits, were not well suited for prescribing PrEP. Providers detailed the need to build capacity and were concerned about monitoring side effects and adherence. PrEP was seen as potentially having impact on the epidemic but providers also noted that community education campaigns needed to be tailored to effectively reach specific vulnerable populations. CONCLUSIONS: While PrEP may be a novel and clinically compelling prevention intervention for MSM and TG women, it raises a number of important implementation challenges that would need to be addressed. Nonetheless, most providers expressed optimism that

  2. Ambivalent participation

    DEFF Research Database (Denmark)

    Groes-Green, Christian

    2012-01-01

    Participation in young peoples' sexual cultures in Maputo, Mozambique led to reflections about the field dynamics of power, participation, desire, and discomfort. Structural inequalities of race, gender, and educational status resulted in informants seeing me as a morally righteous person to whom...... they could not give open accounts about sexual practice. Attempting to overcome these barriers, I participated in excessive nightlife activities, and as a consequence they began viewing me as a more accepting and reliable person. Although breaking down these barriers provided invaluable insight......' continued participation. I show how negotiating the risks of participation may simultaneously satisfy the desire for knowledge and curb erotic desires....

  3. Unfolding Participation

    DEFF Research Database (Denmark)

    Saad-Sulonen, Joanna; Halskov, Kim; Eriksson, Eva

    2015-01-01

    The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding...... the concept itself), while at the same time, 2) reflecting on the way that participation unfolds across different participatory configurations. We invite researchers and practitioners from PD and HCI and fields in which information technology mediated participation is embedded (e.g. in political studies......, urban planning, participatory arts, business, science and technology studies) to bring a plurality of perspectives and expertise related to participation....

  4. Introduction of the Thin Prep Imaging System™ (TIS: experience in a high volume academic practice

    Directory of Open Access Journals (Sweden)

    Chivukula Mamatha

    2007-02-01

    Full Text Available Abstract Objective Since the introduction of the liquid-based ThinPrep testing in 1996, most cytology laboratories across the country have adopted the liquid-based cytology (LBC for Pap test screening. Subsequent to wide-spread adoption of the ThinPrep Pap test, the ThinPrep Imaging System (TIS Cytyc Corp, Marlborough, MA was introduced to improve the accuracy and efficiency of screening interpretation. We report our initial experience with the TIS at Magee Women's Hospital. We introduced the TIS in December 2004. Methods The imager assisted Pap test results over the first 12 months (December 2004 to December 2005 of implementation were reviewed and analyzed. Our implementation protocol included each cytotechnologist manually prescreening 200 negative slides to gain experience with the imager slides and serve as a quality check for the TIS. We re-screened 3400 slides (200 slides each for 17 cytotechnologists manually which were initially determined to be negative using the TIS. 104,457 Pap tests were imaged on the TIS. 95,899 manually screened Pap tests, 12 months prior to the introduction of the TIS (December 2003–November 2004 are taken as the historic control group for our study. Results The mean ASC-US rate employing the automated imager was 8.70% [9088/104,457]. The mean LSIL detection rate was 4.22% [4409/104,457]. The imager did not miss any detectible high-grade lesions during these months, with a HSIL (+ detection rate of 0.68% in comparison to 0.60% by manual screening confirmed by follow-up biopsies. The difference is statistically significant with a p value of 0.022. The definition of false negative rate for purposes of this study is calculated as the number of false negative cases identified out of number of negatives re-screened. The TIS false negative rate was estimated at 0.012% [4/3400]. Conclusion The overall performance of the TIS in our lab appears to be highly satisfactory in terms of improving sensitivity in screening

  5. Unfolding Participation

    DEFF Research Database (Denmark)

    Saad-Sulonen, Joanna; Halskov, Kim; Eriksson, Eva

    2015-01-01

    The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding......, urban planning, participatory arts, business, science and technology studies) to bring a plurality of perspectives and expertise related to participation.......The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding...... the concept itself), while at the same time, 2) reflecting on the way that participation unfolds across different participatory configurations. We invite researchers and practitioners from PD and HCI and fields in which information technology mediated participation is embedded (e.g. in political studies...

  6. CareerTech VISION 2012--Transforming CTE Together

    Science.gov (United States)

    Bray, Janet B.

    2012-01-01

    As the leader in career and technical education (CTE), the Association for Career and Technical Education (ACTE) understands the ongoing challenges faced by the CTE community. That is why ACTE has created CareerTech VISION 2012, a bold and visionary event that addresses the evolving needs of the global society and meets all individual and…

  7. Educating Students to Boost Innovation and High-tech Entrepreneurship

    DEFF Research Database (Denmark)

    Berg, Rolf Henrik

    Promoting innovative thinking among students is crucial to educating the workforce necessary for innovation-led economies. And high-tech entrepreneurs are a crucial source of creating new jobs. Innovation is not an exact discipline or a system one can just implement. By contrast, it is very much...

  8. Job Future's Bright for the Chefs of Muskingum Tech.

    Science.gov (United States)

    Hoffman, Carl

    1993-01-01

    A two-year culinary arts program at Muskingum College (Zanesville, Ohio) prepares students for jobs in an emerging service-based economy. Students receive intensive classroom instruction and hands-on learning in a high-tech kitchen. Twenty-five full-time and 12 part-time students are completing their first year in the program. (LP)

  9. High Touch in a High-Tech World

    Science.gov (United States)

    Gibson, Cindy L.

    2009-01-01

    In a world of high tech and low touch, it is easy for public relations programs to stray from tried-and-true interpersonal strategies long associated with solid communication planning. New technologies allow communications professionals to quickly send e-mails and telephone calls to selected groups. Social media sites provide users immediate…

  10. Virginia Tech study reveals predation-evolution link

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The fossil record seems to indicate that the diversity of marine creatures increased and decreased over hundreds of millions of years in step with predator-prey encounters, Virginia Tech geoscientists report in the proceedings of the National Academy of Science online early edition the week of Sept. 10.

  11. NASA Consortium awards funding to Virginia Tech's geospatial program

    OpenAIRE

    Davis, Lynn

    2004-01-01

    NASA has selected a partnership between the Virginia Space Grant Consortium (VSGC) and Virginia Tech to receive a $100,000 grant for geospatial education and work force development. The grant, awarded through the NASA Space Grant College and Fellowship program, allows the partners to continue the already successful Virginia Geospatial Extension Program that was established in July 2003.

  12. Functional Dyes, and Some Hi-Tech Applications

    Directory of Open Access Journals (Sweden)

    Reda M. El-Shishtawy

    2009-01-01

    Full Text Available An overview of the recent developments in functional dyes, which are useful for hi-tech applications for those based on optoelectronics, such as dye sensitized solar cells, photochromic dyes and biomedical applications, such as photodynamic therapy for the treatment of cancer and fluorescent sensors is presented.

  13. Ten Niche Strategies To Commercialize New High-Tech Products

    NARCIS (Netherlands)

    Ortt, J.R.; Langley, D.J.; Pals, N.

    2013-01-01

    There are serious gaps in the scientific literature relating to niche strategies as a means for commercializing new high-tech products. In particular, there is no clarity about what types of niche strategies can be distinguished, or how a niche strategy can be selected to suit a certain ituation. In

  14. Virginia Tech to host Biodiversity Conservation in Agriculture Symposium

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    Virginia Tech will host the Biodiversity Conservation in Agriculture Symposium at its Caribbean Center for Education and Research in Punta Cana, the Dominican Republic, May 31 - June 2. The symposium is designed to promote inclusion of biodiversity conservation objectives in agricultural development activities.

  15. Virginia Tech administrator receives award from Philippine government

    OpenAIRE

    2004-01-01

    Philippine President Gloria Macapagal Arroyo has honored S. K. De Datta of Blacksburg, associate provost for international affairs at Virginia Tech, with a Presidential Citation Award. The award recognizes De Datta's contributions towards eradicating hunger through improved agricultural productivity and food security, particularly for the production of rice.

  16. Virginia Tech to compete in 2009 Solar Decathlon

    OpenAIRE

    Chadwick, Heather Riley

    2008-01-01

    The U.S. Department of Energy has announced that Virginia Tech will be one of 20 university teams selected to compete in its fourth Solar Decathlon, which will be held on the National Mall in Washington, D.C., in the fall of 2009.

  17. Virginia Tech team places fourth at Solar Decathlon 2005

    OpenAIRE

    Chadwick, Heather Riley

    2005-01-01

    A house designed and built by a team of students from Virginia Tech's College of Architecture and Urban Studies and College of Engineering placed fourth overall on Friday, Oct. 14, at Solar Decathlon 2005, an international competition sponsored by the Department of Energy held on the Mall in Washington, D.C.

  18. Suzhou Institute of Nano-tech and Nano-bionics

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ The Suzhou Institute of Nano-tech and Nano-bionics is co-established by CAS, the provincial government of Jiangsu, and the municipal government of Suzhou, a time-honored urban center and picturesque tourist resort in the Yangtze delta.

  19. A new partnership: joint ventures and high-tech imaging.

    Science.gov (United States)

    Rutherford, R M

    1987-01-01

    Today joint ventures are a viable option for acquiring high-tech, high-priced imaging equipment. In this article based on his RSNA Associated Sciences presentation, Mr. Rutherford discusses a variety of issues concerning joint ventures: planning, tax considerations, structure and the ethics question.

  20. ASM International : Family tech enterprise grows up: Part A

    NARCIS (Netherlands)

    Lachotzki, F.W.I.; Schuit, S.R.; Olson, M.A.

    2012-01-01

    High-tech innovation is something not confined to the US, and indeed for decades the Dutch-based company ASMI has been a strong worldwide competitor in the market for the highly-complicated machines which manufacture the semi-conducter chips which are to be found in all modern-day electronic devices

  1. Employment and Earnings in High-Tech Ethnic Niches

    Science.gov (United States)

    Lee, Jennifer C.

    2013-01-01

    The increase in high-skilled immigrants to the United States coincided with the expansion of the high-technology sector, and now a large share of Asian immigrants concentrate in high-tech industries. Despite much research on the relationship between ethnic concentration and labor market outcomes, the association between ethnic niche employment and…

  2. Business, industry, government preview energy research at Virginia Tech Showcase

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    The Nov. 29-30 Energy Research Engagement Showcase offers business and community leaders the opportunity to learn about more than 300 energy-related activities at Virginia Tech, as well as energy efforts by faculty members at other public universities in Virginia.

  3. Examination of the New Tech Model as a Holistic Democracy

    Science.gov (United States)

    Bradley-Levine, Jill; Mosier, Gina

    2017-01-01

    Using the Degrees of Democracy Framework (Woods & Woods, 2012), we examined eight New Tech (NT) high schools to determine the extent to which they demonstrated characteristics of holistic democracy. We collected qualitative data, including observations and interviews during the fourth year of implementation. Findings indicated that the eight…

  4. CHARCOAL PACKED FURNACE FOR LOW-TECH CHARRING OF BONE

    DEFF Research Database (Denmark)

    Jacobsen, P.; Dahi, Elian

    1997-01-01

    A low-tech furnace for charring of raw bone using char coal is developed and tested. The furnace consists of a standard oil drum, fitted with simple materials as available in every market in small towns in developing counties. 80 kg of raw bone and 6 kg of charcoal are used for production of 50 k...

  5. Report on Virginia Tech Shootings Urges Clarification of Privacy Laws

    Science.gov (United States)

    Fischer, Karin

    2007-01-01

    Educators, mental-health officials, and law-enforcement officers often do not share information about troubled students because they are confused by what they can disclose under complex and overlapping privacy laws, according to a report on the Virginia Tech shootings. Attorney General Alberto R. Gonzales and two other Bush cabinet secretaries…

  6. Another Innovation from High Tech High--Embedded Teacher Training

    Science.gov (United States)

    Griswold, Janie; Riordan, Rob

    2016-01-01

    High Tech High School's teaching internship program blends on-the-job work with classroom theory. Interns spend two years working as full teachers as they take courses. The program serves three large purposes: Train new teachers and build capacity in the HTH organization; train teachers in and beyond HTH for success in a wide range of contexts;…

  7. Willingness to use pre-exposure prophylaxis (PrEP for HIV prevention among men who have sex with men (MSM in Malaysia: findings from a qualitative study

    Directory of Open Access Journals (Sweden)

    Adam Bourne

    2017-01-01

    Conclusions: This qualitative study indicates that, broadly speaking, PrEP may be acceptable to MSM in Malaysia. However, in order for its potential to be realized, and uptake achieved, educative interventions are required to inform the target population as to the efficacy and potential, positive impact of PrEP. Given concerns for how those taking it may be stigmatized, it is crucial that the use of PrEP is presented as a responsible course of action, and one of a range of strategies that men can use to keep themselves safe from HIV.

  8. TechCare: mobile assessment and therapy for psychosis – an intervention for clients in the Early Intervention Service: A feasibility study protocol

    Directory of Open Access Journals (Sweden)

    Nusrat Husain

    2016-10-01

    Full Text Available Objectives: Technological advances in healthcare have shown promise when delivering interventions for mental health problems such as psychosis. The aim of this project is to develop a mobile phone intervention for people with psychosis and to conduct a feasibility study of the TechCare App. Methods: The TechCare App will assess participant’s symptoms and respond with a personalised guided self-help-based psychological intervention with the aim of exploring feasibility and acceptability. The project will recruit 16 service users and 8–10 health professionals from the Lancashire Care NHS Foundation Trust Early Intervention Service. Results: In strand 1 of the study, we will invite people to discuss their experience of psychosis and give their opinions on the existing evidence-based treatment (cognitive behavioural therapy and how the mobile app can be developed. In strand 2, we will complete a test run with a small number of participants (n = 4 to refine the mobile intervention (TechCare. Finally, in strand 3 of the study, the TechCare App will be examined in a feasibility study with 12 participants. Conclusion: It has been suggested that there is a need for a rapid increase in the efforts to develop the evidence base for the clinical effectiveness of digital technologies, considering mHealth research can potentially be helpful in addressing the demand on mental health services globally.

  9. TRAINING EMPLOYEES TO WORK WITH HI-TECH EQUIPMENT

    Directory of Open Access Journals (Sweden)

    M. A. Dremina

    2016-01-01

    Full Text Available The aim of the study is to describe a research relying on the capabilities of networking, which improves the quality of vocational training of skilled workers that are intended to work with new hi-tech equipment.Methods. Methods of system and comparative analysis, modeling, synthesis and generalization are used. Specification of the model of workers training offered by authors is carried out on the basis of deep interviews to experts – the representatives of the large enterprises who are carrying out training of the personnel.Results. Social and pedagogical contradictions are revealed, on the one hand, in the growing need for highly professional personnel for hi-tech productions, and, on the other hand, in insufficiently effective countermeasures of the system of vocational education and training on closing actual requirements of productions. The discrepancies reducing the quality of preparation of skilled workers are revealed by comparative analysis of competences based on an ideal competence model of the trainer and teacher of VET with the competences presented in educational both professional standards and the discussed projects. Characteristics of the existing pedagogical process in the hi-tech production environment are described. For the purpose of quality improvement of the pedagogical process, the network format of interactions of the enterprise, educational and the business organizations is offered.Scientific novelty. The concept «pedagogical process» for the purpose of making it more instrumental is specified; it joins a technological process and the design of its ideal model for the hi-tech production environment. The unique network project including design and development of innovative manuals and teaching materials for the welding equipment of Fronius International GmbH.Practical significance. The research results can be useful to the management of staff development and career advancement of hi-tech productions, and VET

  10. Esthetic Rehabilitation of the Smile with No-Prep Porcelain Laminates and Partial Veneers

    Directory of Open Access Journals (Sweden)

    Arcelino Farias-Neto

    2015-01-01

    Full Text Available Rehabilitation of patients with anterior conoid teeth may present a challenge for the clinician, especially when trying to mimic the nature with composite resins. This clinical report exemplifies how a patient with conoid upper lateral incisors was rehabilitated with minimally invasive adhesive restorations. Following diagnostic wax-up and cosmetic mock-up, no-prep veneers and ceramic fragments (partial veneers were constructed with feldspathic porcelain. This restorative material presents excellent reproduction of the optical properties of the dental structure, especially at minimal thicknesses. In this paper, the details about the treatment are described. A very pleasing outcome was achieved, confirming that minimally invasive adhesive restorations are an excellent option for situations in which the dental elements are healthy, and can be modified exclusively by adding material and the patient does not want to suffer any wear on the teeth.

  11. Esthetic Rehabilitation of the Smile with No-Prep Porcelain Laminates and Partial Veneers.

    Science.gov (United States)

    Farias-Neto, Arcelino; Gomes, Edna Maria da Cunha Ferreira; Sánchez-Ayala, Alfonso; Sánchez-Ayala, Alejandro; Vilanova, Larissa Soares Reis

    2015-01-01

    Rehabilitation of patients with anterior conoid teeth may present a challenge for the clinician, especially when trying to mimic the nature with composite resins. This clinical report exemplifies how a patient with conoid upper lateral incisors was rehabilitated with minimally invasive adhesive restorations. Following diagnostic wax-up and cosmetic mock-up, no-prep veneers and ceramic fragments (partial veneers) were constructed with feldspathic porcelain. This restorative material presents excellent reproduction of the optical properties of the dental structure, especially at minimal thicknesses. In this paper, the details about the treatment are described. A very pleasing outcome was achieved, confirming that minimally invasive adhesive restorations are an excellent option for situations in which the dental elements are healthy, and can be modified exclusively by adding material and the patient does not want to suffer any wear on the teeth.

  12. Impact of gender and personality traits (BFI-10) on tech savviness

    DEFF Research Database (Denmark)

    Pavlicek, Antonin; Sudzina, Frantisek; Malinova, Ludmila

    2017-01-01

    Nowadays, it is necessary to use technology in various everyday activities. A certain level of what used to be called high-tech savviness is needed to access almost all modern services. The aim of this paper is to analyze if gender and personality traits (Big Five Inventory-10) influence self......-perceived tech savviness. A not so surprising finding is that gender influences self-perceived tech savviness, i.e. men consider themselves more tech savvy. Moreover, neuroticism has a negative and openness to experience has a positive impact on self-perceived tech savviness....

  13. Conceptualizing Participation

    DEFF Research Database (Denmark)

    Simovska, Venka; Bruun Jensen, Bjarne

    Although participation is not a new issue, it would be fair to say that consequential participation, which implies young people engaging in meaningful dialogue with adults and institutions and influencing decision-making processes in matters that concern them, is still in its infancy. This document...... and society. It then describes different forms, modes or qualities of participation and proposes a specific model of facilitating participatory work with young people - the IVAC approach (Investigation-Vision-Action-Change). The concept of action, types of actions aimed at initiating change and corresponding...... aims to set the scene for discussing young people's participation in different domains that have an impact on their lives. It outlines the meaning and different interpretations of the concept of "participation" before reviewing why participation is an important issue in relation to young people...

  14. Exploring TechQuests Through Open Source and Tools That Inspire Digital Natives

    Science.gov (United States)

    Hayden, K.; Ouyang, Y.; Kilb, D.; Taylor, N.; Krey, B.

    2008-12-01

    "There is little doubt that K-12 students need to understand and appreciate the Earth on which they live. They can achieve this understanding only if their teachers are well prepared". Dan Barstow, Director of Center for Earth and Space Science Education at TERC. The approach of San Diego County's Cyberinfrastructure Training, Education, Advancement, and Mentoring (SD Cyber-TEAM) project is to build understandings of Earth systems for middle school teachers and students through a collaborative that has engaged the scientific community in the use of cyber-based tools and environments for learning. The SD Cyber-TEAM has used Moodle, an open source management system with social networking tools, that engage digital native students and their teachers in collaboration and sharing of ideas and research related to Earth science. Teachers participate in on-line professional dialog through chat, wikis, blogs, forums, journals and other tools and choose the tools that will best fit their classroom. The use of Moodle during the Summer Cyber Academy developed a cyber-collaboratory environment where teaching strategies were discussed, supported and actualized by participants. These experiences supported digital immigrants (teachers) in adapting teaching strategies using technologies that are most attractive and familiar to students (digital natives). A new study by the National School Boards Association and Grunwald Associates LLC indicated that "the online behaviors of U.S. teens and 'tweens shows that 96 percent of students with online access use social networking technologies, such as chatting, text messaging, blogging, and visiting online communities such as Facebook, MySpace, and Webkinz". While SD Cyber-TEAM teachers are implementing TechQuests in classrooms they use these social networking elements to capture student interest and address the needs of digital natives. Through the Moodle environment, teachers have explored a variety of learning objects called Tech

  15. Authoring Participation

    DEFF Research Database (Denmark)

    Papazu, Irina

    2016-01-01

    . By turning to material participation, a concept inspired by Noortje Marres and Jennifer Gabrys, the efforts put into Samsø’s energy transformation by the islanders are given specificity. While much literature on public participation foregrounds public meetings and other spaces for deliberation and debate...

  16. GE Smart Prep半自动监控软件的应用要点%Application Keypoints of GE Light Speed 8 Smart Prep Semiautomatic Monitoring Software

    Institute of Scientific and Technical Information of China (English)

    肖建明

    2011-01-01

    目的 探讨GE light speed 8 smart Prep技术在CT血管造影中的准确应用.方法 采用GE light speed 8 Smart Pmp软件对35例患者进行颅脑CTA检查.结果 总结出GE light speed 8运用smart prep 的技术要点.%Objective To investigate the application of the GE light speed 8 smart prep technique in CT angiography. Methods Used GE light speed 8 Smart Prep software to assist the check of cerebral CTA in 35 patients. Results Summarized the application keypoints of CE light speed 8 smart prep technique.

  17. Prevalence and characteristics of users of pre-exposure prophylaxis (PrEP) among men who have sex with men, San Francisco, 2014 in a cross-sectional survey: implications for disparities.

    Science.gov (United States)

    Snowden, Jonathan M; Chen, Yea-Hung; McFarland, Willi; Raymond, Henry F

    2017-02-01

    Pre-exposure prophylaxis (PrEP) has gained a central role in prevention of HIV infection among men who have sex with men (MSM), particularly in San Francisco, California, USA. Programmes to enrol men in PrEP are being undertaken by a range of public and private organisations. PrEP will have the largest population impact if it reaches men who are most at risk for HIV infection, and is used in a manner that enables maximal efficacy. Access to PrEP also needs to be equitable. We report on the characteristics of men eligible for and using PrEP. Data were from the 2014 implementation of National HIV Behavioural Surveillance (NHBS) among MSM in San Francisco. NHBS uses venue-based sampling as the national standard for sampling MSM. We compare proportions of demographic characteristics of MSM using versus not using PrEP who are HIV-negative and meet Centers for Disease Control and Prevention guidelines to recommend PrEP. Overall, 64.1% of HIV-negative MSM in San Francisco would meet guidelines for PrEP use, while 9.2% of MSM overall and 14.5% of MSM eligible were using PrEP as of 2014. Men using PrEP are more likely to be white and of older age. There were no differences between men using and not using PrEP in terms of education, income and health insurance. PrEP roll-out efforts should attempt to increase reach for young, black and Hispanic MSM. Failure to equitably provide access to PrEP could exacerbate the US disparity in new HIV infections for men of colour. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  18. Pre-exposure Prophylaxis (PrEP) Use, Seroadaptation, and Sexual Behavior Among Men Who Have Sex with Men, San Francisco, 2004-2014.

    Science.gov (United States)

    Chen, Yea-Hung; Snowden, Jonathan M; McFarland, Willi; Raymond, H Fisher

    2016-12-01

    The Food and Drug Administration approved pre-exposure prophylaxis (PrEP) to prevent HIV infection, and the Centers for Disease Control and Prevention has presented PrEP as a prevention option for groups at high risk such as men who have sex with men (MSM). Intervention data provide some information on how PrEP affects sexual behavior of MSM in trials, open label extensions, or clinics. However, it is unclear whether sexual risk and preventive behavioral patterns are changing in the population as a whole as PrEP becomes more widely available, whether due to PrEP use or other factors. We examined trends in PrEP use, numbers of condomless anal sex partners, consistent condom use, and seroadaptive strategies in San Francisco-a city which has actively promoted PrEP-using data from National HIV Behavioral Surveillance (NHBS). NHBS recruited 1211, 383, 373, and 268 HIV-negative MSM in 2004, 2008, 2011, and 2014, respectively. PrEP use increased from zero in 2004, 2008, and 2011 to 9.6 % in 2014. The proportion of men with no condomless anal sex partners dropped from 60.6 % in 2004, to 58.2 % in 2008, to 54.2 % in 2011, to 40.2 % in 2014. Consistent condom use decreased from 36.8 % in 2004, and 30.5 % in 2008 and 2011, to 18.3 % in 2014. PrEP's introduction and scale-up enters in a pre-existing trend of decreasing condom use and increasing sexually transmitted infections among MSM which may be accelerating in recent years. While PrEP use should be scaled up as a prevention option among those who would benefit most, we believe that public health officials need to be realistic about the possibility that condom use could very well continue to decline as PrEP use increases, and to an extent that may not be directly or indirectly offset by PrEP.

  19. Evaluation of an Upgraded Version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 Test for HIV-1 Load Quantification▿

    OpenAIRE

    Damond, F.; Avettand-Fenoel, V.; Collin, G.; Roquebert, B.; Plantier, J. C.; Ganon, A.; Sizmann, D.; Babiel, R. (Rainer); Glaubitz, J.; Chaix, M. L.; Brun-Vezinet, F.; Descamps, D; Rouzioux, C

    2010-01-01

    We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated.

  20. Evaluation of an Upgraded Version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 Test for HIV-1 Load Quantification▿

    Science.gov (United States)

    Damond, F.; Avettand-Fenoel, V.; Collin, G.; Roquebert, B.; Plantier, J. C.; Ganon, A.; Sizmann, D.; Babiel, R.; Glaubitz, J.; Chaix, M. L.; Brun-Vezinet, F.; Descamps, D.; Rouzioux, C.

    2010-01-01

    We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated. PMID:20129964

  1. Evaluation of an upgraded version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test for HIV-1 load quantification.

    Science.gov (United States)

    Damond, F; Avettand-Fenoel, V; Collin, G; Roquebert, B; Plantier, J C; Ganon, A; Sizmann, D; Babiel, R; Glaubitz, J; Chaix, M L; Brun-Vezinet, F; Descamps, D; Rouzioux, C

    2010-04-01

    We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated.

  2. When are declines in condom use while using PrEP a concern? Modelling insights from a Hillbrow, South Africa case study

    Directory of Open Access Journals (Sweden)

    Hannah Grant

    2017-01-01

    Full Text Available Introduction: Oral pre-exposure prophylaxis (PrEP is a promising new prevention approach for those most at risk of HIV infection. However, there are concerns that behavioural disinhibition, specifically reductions in condom use, might limit PrEP’s protective effect. This study uses the case of female sex workers (FSWs in Johannesburg, South Africa, to assess whether decreased levels of condom use following the introduction of PrEP may limit HIV risk reduction.Methods: We developed a static model of HIV risk and compared HIV-risk estimates before and after the introduction of PrEP to determine the maximum tolerated reductions in condom use with regular partners and clients for HIV risk not to change. The model incorporated the effects of increased STI exposure owing to decreased condom use. Noting that condom use with regular partners is generally low, we also estimated the change in condom use tolerated with clients only, to still achieve 50 and 90% risk reduction on PrEP. The model was parameterized using data from Hillbrow, Johannesburg. Sensitivity analyses were performed to ascertain the robustness of our results.Results: Reductions in condom use could be tolerated by FSWs with lower baseline condom use (65%. For scenarios where 75% PrEP effectiveness is attained, 50% HIV-risk reduction on PrEP would be possible even with 100% reduction in condom use from consistent condom use as high as 70% with clients. Increased exposure to STIs through reductions in condom use had limited effect on the reductions in condom use tolerated for HIV risk not to increase on PrEP.Conclusions: PrEP is likely to be of benefit in reducing HIV risk, even if reductions in condom use do occur. Efforts to promote consistent condom use will be critical for FSWs with high initial levels of condom use, but with challenges in adhering to PrEP.

  3. Comparing the impact of increasing condom use or HIV pre-exposure prophylaxis (PrEP use among female sex workers

    Directory of Open Access Journals (Sweden)

    Zindoga Mukandavire

    2016-03-01

    Full Text Available In many settings, interventions targeting female sex workers (FSWs could significantly reduce the overall transmission of HIV. To understand the role HIV pre-exposure prophylaxis (PrEP could play in controlling HIV transmission amongst FSWs, it is important to understand how its impact compares with scaling-up condom use—one of the proven HIV prevention strategies for FSWs. It is important to remember that condoms also have other benefits such as reducing the incidence of sexually transmitted infections and preventing pregnancy. A dynamic deterministic model of HIV transmission amongst FSWs, their clients and other male partners (termed ‘pimps’ was used to compare the protection provided by PrEP for HIV-negative FSWs with FSWs increasing their condom use with clients and/or pimps. For different HIV prevalence scenarios, levels of pimp interaction, and baseline condom use, we estimated the coverage of PrEP that gives the same reduction in endemic FSW HIV prevalence or HIV infections averted as different increases in condom use. To achieve the same impact on FSW HIV prevalence as increasing condom use by 1%, the coverage of PrEP has to increase by >2%. The relative impact of PrEP increases for scenarios where pimps contribute to HIV transmission, but not greatly, and decreases with higher baseline condom use. In terms of HIV infections averted over 10 years, the relative impact of PrEP compared to condoms was reduced, with a >3% increase in PrEP coverage achieving the same impact as a 1% increase in condom use. Condom promotion interventions should remain the mainstay HIV prevention strategy for FSWs, with PrEP only being implemented once condom interventions have been maximised or to fill prevention gaps where condoms cannot be used.

  4. BiblioTech why libraries matter more than ever in the age of Google

    CERN Document Server

    Palfrey, John

    2015-01-01

    Libraries today are more important than ever. More than just book repositories, libraries can become bulwarks against some of the most crucial challenges of our age: unequal access to education, jobs, and information. In BiblioTech, educator and technology expert John Palfrey argues that anyone seeking to participate in the 21st century needs to understand how to find and use the vast stores of information available online. And libraries, which play a crucial role in making these skills and information available, are at risk. In order to survive our rapidly modernizing world and dwindling government funding, libraries must make the transition to a digital future as soon as possible—by digitizing print material and ensuring that born-digital material is publicly available online. Not all of these changes will be easy for libraries to implement. But as Palfrey boldly argues, these modifications are vital if we hope to save libraries and, through them, the American democratic ideal.

  5. Partial-prep bonded restorations in the anterior dentition: Long-term gingival health and predictability. A case report.

    Science.gov (United States)

    Molina, Ivan Contreras; Molina, Gil Contreras; Stanley, Kyle; Lago, Carlo; Xavier, Clessius Ferreira; Volpato, Claudia Angela Maziero

    2016-01-01

    Bonded porcelain restorations are a predictable and durable treatment option that can restore not only the strength and function of the teeth but also the esthetic appearance. One important issue in adhesive dentistry is the preservation of sound enamel. Following biomimetic principles, employing minimally invasive applications and adhesive technologies is of paramount importance for successful restorations. While it is widely accepted that minimally invasive restorative techniques should be favored, there is still some controversy over the noninvasive approaches. The purpose of this article is to question the complete "no-prep veneer" concept due to the possible negative effects on periodontal health caused by excessive contour and overhangs of the ceramic restoration, and to propose a new method to assess the quality and longevity of veneers with a partial-prep concept.

  6. Virginia Tech Wildlife Student Studies Cheetah Home Ranges

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The cheetah may be the world's fastest land animal, accelerating to high speeds in just a few steps, but within recent years the cheetahs of South Africa are battling the race for survival. To find remedies for this problem Peter Laver, a graduate student in fisheries and wildlife sciences in the College of Natural Resources at Virginia Tech, is expanding current research on home ranges of the cheetah population located in the Serengeti National Park in Tanzania, Africa.

  7. Information literacy training in AgroParisTech food studies

    OpenAIRE

    Agnès Grimal; Florence Dubois-Brissonnet; Elisabeth Dumoulin

    2015-01-01

    AgroParisTech professors and librarians in Food Science and Technology have developed information literacy instruction to help students find and use relevant information. The course trains students to develop information literacy competencies: to identify the information needed and define its nature and extent; to access the information with efficiency because they select and use methods, resources and retrieval systems most appropriate to the topic; to evaluate the used methods, information,...

  8. Life Sciences at the University of Yachay Tech in Ecuador

    OpenAIRE

    Graciela Salum; Si Amar Dahoumane; Agathos, Spiros N.

    2016-01-01

    Yachay Tech University, home for more than 900 students and growing, has entered a new era and made a step forward in its development and fulfillment of the hopes placed on it. Indeed, its Schools have launched their careers offering the students a wide range of choices among programs of high academic level. The School of Biological Sciences and Engineering has started its two careers. The first one, coined "Biology," is designed for students aiming to gain knowledge either in "Organism...

  9. Virginia Tech Wildlife Student Studies Cheetah Home Ranges

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The cheetah may be the world's fastest land animal, accelerating to high speeds in just a few steps, but within recent years the cheetahs of South Africa are battling the race for survival. To find remedies for this problem Peter Laver, a graduate student in fisheries and wildlife sciences in the College of Natural Resources at Virginia Tech, is expanding current research on home ranges of the cheetah population located in the Serengeti National Park in Tanzania, Africa.

  10. Orientace na konkurenci u hi-tech podniků

    Directory of Open Access Journals (Sweden)

    Lucie Kaňovská

    2013-10-01

    Full Text Available Purpose: The purpose of this paper is to examine the connection between market orientation and mainly competitor orientation and business performance at the hi-tech companies in the Czech Republic. Design/methodology/approach: The paper involves the New Method for measuring of market orientation. Data are collected through the survey and were used for the data analysis. Findings: The paper involves new aspects for perceiving competitor orientation, as a part of market orientation, and business performance. The result concurs with the results of researches of market orientation realized at this branch. Results show that competitor orientation has significant influence on business performance. Research limitations implications: The limitations are based on the methodology used for gaining data. However, the overall response rate is almost 20 %. The hi-tech industry is fast changing. From this reason, there can be many changes and it is impossible to repeat the research at the same companies. Practical implications: Our findings can help to understand market orientation and its relationship to competitors and business performance. Managers can use method for measuring of market orientation and can find out the level of market orientation at their companies. They can compare their results with the published average results of hi-tech companies. Originality/value: The originality of the paper comes from combining market orientation, the view of competition and business performance at hi-tech companies. The measurement of market orientation was made through the New Method. The model of the New method was constructed along after analysis of other 25 methods; we tried to eliminate the failings criticized in other methods.

  11. Virginia Tech to offer intensive English language refresher courses

    OpenAIRE

    2003-01-01

    Speaking and writing professionally with confidence are difficult for virtually everyone, but for those using a second language, these tasks pose a unique challenge. Virginia Tech's English Language Institute will address these needs by offering two intensive English language skills refresher classes during the semester break, from Jan. 5 to Jan. 16, 2004. Designed for graduate students, post-doctoral fellows, visiting scholars, and members of the international research community, this two-we...

  12. Entrepreneurship in high-tech and knowledge-intensive sectors

    DEFF Research Database (Denmark)

    Christensen, Patrizia V.; Madsen, Henning; Neergaard, Helle

    development of new enterprises in high-tech and knowledge-intensive sectors are analysed in relation to the educational and professional background of the entrepreneur/entrepreneurial team, as well as the personal and professional social networks of the entrepreneurs. The analysis is based on a theoretical...... framework combining theories of human and social capital. Secondary aspects addressed in the research project are questions of male vs. female entrepreneurship, internationalisation-globalisation, and business success/failure....

  13. Wearable high-tech gear for homeland security personnel

    Science.gov (United States)

    Venkateswarlu, Ronda; Hui Wei, Choo; Li Lian, Ngiam; Lim, E. T.; Zhu, Zijian; Yang, Mingjiang

    2006-05-01

    Recent homeland security problems in various countries indicate that fixed surveillance systems at important places are not adequate enough. As the security threats take new dimensions in future, mobile smart security personnel wearing high-tech gear will form the basic infrastructure. See first, listen first, detect first, track first, communicate first with peers, assess the threat and coordinate with security head-quarters are the functions of high-tech gear. This paper proposes a high-tech gear involving (i) hands-free and obtrusion-free textile-based wearable microphone array to capture users voice and interface with body-worn computer, (ii) microphone arrays embedded in textiles to listen and record others voices from a distance, (iii) miniature cameras embedded in the shirt to provide the user with omni vision (iv) wireless personal display as GUI hidden in textile or natural glasses, (v) GPS and body area network for positional awareness for information in the form of text or textile integrated, (vi) reconfigurable HW/SW for all the above functions configured in the form of a usual belt. The main focus of this paper is how to configure the high-tech gear with all these sophisticated functions to disappear into the natural wearables of the user giving him normal look in the public. This project is sponsored by Defence Science & Technology Agency, Ministry of Defence, Singapore. This paper covers multi-discipline technologies at system level, hence not possible to go into details of any subsystem. The main objective of this paper is to share our thoughts and get feedback. Progress and some critical design issues are discussed in this paper.

  14. Understanding Mexican High-tech Organizations: A Conceptualization Problem?

    OpenAIRE

    2001-01-01

    Working paper serie RMT (WPS 01-07), 23 p.; This study investigates the differences between intensive technology and low-tech firms located in Mexico, focusing on the Human Resources Management functions. 31 interviews and 50 answered questionnaires were used in this analysis. The results show that while Mexico is not yet a fully developed technological country. Indeed, technologically intensive firms are rare cases. Mexico is progressing rapidly towards a technologically developed country in...

  15. Information literacy training in AgroParisTech food studies

    Directory of Open Access Journals (Sweden)

    Agnès Grimal

    2015-10-01

    Full Text Available AgroParisTech professors and librarians in Food Science and Technology have developed information literacy instruction to help students find and use relevant information. The course trains students to develop information literacy competencies: to identify the information needed and define its nature and extent; to access the information with efficiency because they select and use methods, resources and retrieval systems most appropriate to the topic; to evaluate the used methods, information, and sources; to search, access and use information ethically and legally; to read, use and write bibliographic references.AgroParisTech trains two kinds of students. For Higher Education students (engineering students, the training takes place at their arrival in AgroParisTech, including courses and practical classes: role and management of information in organizations; information on plagiarism; resources in environment, food science and technology; use of relevant tools and methods for searching in databases; reference writing.For students attending a Master of Science, the training prepares them to produce a literature review. The curriculum includes: information about scientific integrity, plagiarism; information needed for a researcher; critical reading of a journal article; how to manage a literature review: resources used, information search with databases, full text access; reference writing.The students will use these information literacy skills along their studies as well as in their future jobs.

  16. Guide for the preparation of proposals for the Pre-Freshman Engineering Program: PREP-1981, (for minorities and women)

    Energy Technology Data Exchange (ETDEWEB)

    1980-08-01

    The Pre-Freshman Engineering Program (PREP) for minorities and women (formerly PREFACE) will provide funds to colleges and universities for projects aimed at seeking out minority group individuals and women during junior high school and high school years (7th grade through the summer preceding matriculation in college) and providing them with enrichment experiences. Preparation and submission of proposals, evaluation and selection of proposals for support, and preparation of the final report are described.

  17. Cervical cancer incidence after normal cytological sample in routine screening using SurePath, ThinPrep, and conventional cytology

    DEFF Research Database (Denmark)

    Rozemeijer, Kirsten; Naber, Steffie K; Penning, Corine

    2017-01-01

    Objective To compare the cumulative incidence of cervical cancer diagnosed within 72 months after a normal screening sample between conventional cytology and liquid based cytology tests SurePath and ThinPrep.Design Retrospective population based cohort study.Setting Nationwide network and registry...... of histo- and cytopathology in the Netherlands (PALGA), January 2000 to March 2013.Population Women with 5 924 474 normal screening samples (23 833 123 person years).Exposure Use of SurePath or ThinPrep versus conventional cytology as screening test.Main outcome measure 72 month cumulative incidence...... was 58.5 (95% confidence interval 54.6 to 62.7) per 100 000 normal conventional cytology samples, compared with 66.8 (56.7 to 78.7) for ThinPrep and 44.6 (37.8 to 52.6) for SurePath. Compared with conventional cytology, the hazard of invasive cancer was 19% lower (hazard ratio 0.81, 95% confidence...

  18. PREFACE: 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015)

    Science.gov (United States)

    Gaol, F. L.

    2015-06-01

    The 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015), was held at The Westin Resort Nusa Dua, Bali on 31 January - 1 February 2015. The ScieTech 2015 conference is aimed to bring together researchers, engineers and scientists from around the world. ScieTech 2015 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within mathematics, chemistry and physics. As we already know that science and technology have brought tremendous benefits for human civilization. People are becoming healthier, wealthier, better educated, more peaceful, increasingly connected, and living longer. Of course, science and technology provide many answers to global challenges, but we will face more complex problems in the next decade due to increasing world population, limitation of energy, and climate change. Therefore, researchers should be more active in conducting research that enables collaboration between one and the others. Interdisciplinary cooperation is absolutely necessary in order to create a smart system for solving the global problems. We need a global and general long-term view of the future with long-range goals for solving complex problems in next decade. Therefore the conference was held to be a forum for researchers from different disciplines to start collaborating and conducting research that provides a solution to the global issues. The theme of ScieTech 2015 was ''The interdisciplinary Application between Mathematics, Chemistry and Physics to enhance the Quality of Life''. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting conference program as well as the invited and plenary speakers. This year, we received 197 papers and after rigorous review, 59 papers were accepted. The participants came from 19

  19. The design of civic technology: factors that influence public participation and impact.

    Science.gov (United States)

    May, Andrew; Ross, Tracy

    2017-07-26

    Civic technology needs to be better understood in terms of the factors that promote representative public participation and impact. This paper reports on a mixed-methods study of a civic tech platform that enabled the public to provide feedback on public transport to the service providers. The overall aim of this research was to investigate the public's use of a leading civic tech platform, FixMyTransport. The key findings were that: an effective and easy-to-use civic technology platform enables broad participation; data and process complexity need to be removed; factual information can be captured in situ with impacts, consequences and opinions added later; emotions (if important) need to be explicitly elicited; feedback to, and a 'conversation' with, the users is important for engagement, as is a feeling of being part of a community. These findings can contribute to the future design of civic technology platforms. Practitioner Summary: There is a lack of understanding of how 'civic tech' platforms are used and how they may be designed for maximum effectiveness. Multiple data collection methods were used to investigate a well-developed example of civic tech. Effective civic tech can enable broad democratic participation to improve public services.

  20. Claiming Participation

    DEFF Research Database (Denmark)

    Fabian, Louise; Samson, Kristine

    2015-01-01

    with participation are currently strong influential factors in Danish planning. The article explores the use of participatory DIY urban design in two cases: the relocation of beer drinkers in Enghave Square and the Carlsberg City development in Copenhagen, Denmark. Carlsberg City is the most thorough Danish example...

  1. Quantitative Detection of Screening for Cervical Lesions with ThinPrep Cytology Test

    Institute of Scientific and Technical Information of China (English)

    Hong-xin ZHANG; Yi-min SONG; Su-hong LI; Yu-hui YIN; Dong-ling GAO; Kui-sheng CHEN

    2010-01-01

    OBJECTIVE To investigate the available parameters in gynecological screening for cervical lesions by liquid-based cytology technology (ThinPrep Cytology Test, TCT) and The Bethesda System (TBS), also with computer image analysis. METHODS With application of the image analysis system, all grades of cervical lesion cells were detected quantitatively and sorted in atypical squamous cells of undetermined significance (ASCUS), atypical squamous cells-cannot exclude HSIL (ASC-H), low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL) and cervical squamous cell carcinoma (SCC) with the mean optical density (MOD), average grey (AG), positive units (PU), and nucleus to cytoplasmic ratio (N:C). Differences between each group of cells were compared and analyzed statistically.RESULTS Apart from four stereologic parameters in LSIL and HSIL groups there were no differences among them, in the other groups, there was statistically significant in differences between MOD, AG and PU values. Differences between them in the ratio of nucleus to cytoplasm were highly statistically signifi cant. CONCLUSION Stereological indexes may serve as a screening tool for cervical lesions. The image analysis system is expected to become a new means of cytological assisted diagnosis.

  2. Morphologic features of prostatic adenocarcinoma on ThinPrep® urinary cytology.

    Science.gov (United States)

    Tyler, Kevin L; Selvaggi, Suzanne M

    2011-02-01

    Malignant cells of prostatic adenocarcinoma are rarely identified in urine. In most cases, this finding is associated with high stage tumor. Numerous descriptions of the morphology of prostatic adenocarcinoma have been reported using cytocentrifugated specimens. However, no specific morphologic description of prostatic adenocarcinoma in urine using liquid-based cytology has been previously described. Four cases of prostatic adenocarcinoma in urine using ThinPrep® liquid-based preparations were identified between 2002 and 2009 at the University of Wisconsin Hospital and Clinics. Three patients had either high stage tumor or metastatic disease at the time of diagnosis, while the remaining patient had low stage tumor. The morphology of each case was evaluated with specific attention to cell size, nuclear characteristics, nuclear to cytoplasmic ratio, and cytoplasmic characteristics. The resulting key features for prostatic adenocarcinoma in urine are clustering, increased nuclear to cytoplasmic ratio, and prominent nucleoli. Though typically the presence of prostatic adenocarcinoma in urine implies high stage tumor, cells of lower stage tumors may be seen in urine as well.

  3. Design and Realization of Information System for Ningxia Sci-tech Special Commissioners

    Institute of Scientific and Technical Information of China (English)

    Changhong; WANG

    2013-01-01

    The information system for Ningxia sci-tech special commissioners is an application system for realizing information collection,management and sharing in the entrepreneurial process of sci-tech special commissioners. This paper introduces overall design ideas,system functions,key technologies and realization methods of the information system for Ningxia sci-tech special commissioners. Completion of construction and coming into operation of the information system bring new breakthrough for information management and data statistics of sci-tech special commissioners.

  4. Hi-Tech and Fong’s show up on the ITMA

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The once every four years ITMA exhibition was held recently in Barcelona, Spain.China Hi-Tech Group Corporation attaches great importance on the exhibition as it is a grand event of textile industry. The total exhibition area for Hi-Tech Group and its branch companies is 1100 square meters including 11 equipments of cotton spinning, dyeing and finishing, nonwoven, which represents part of the latest research results of Hi-Tech Group. Moreover other machinery products of Hi-Tech Group are demonstrated on the exhibition through video, pictures and brochure.

  5. Low Tech Hacking Street Smarts for Security Professionals

    CERN Document Server

    Wiles, Jack; Jabbusch, Jennifer; Rogers, Russ; Lowther, Sean

    2011-01-01

    Criminals using hacking techniques can cost corporations, governments, and individuals millions of dollars each year. While the media focuses on the grand-scale attacks that have been planned for months and executed by teams and countries, there are thousands more that aren't broadcast. Low Tech Hacking focuses on the everyday hacks that, while simple in nature, actually add up to the most significant losses. Attackers are using common techniques like social engineering, wireless hacking, and targeting and surveillance to gain access to valuable data. This book contains detailed descriptions

  6. Black Hole - Neutron Star Binary Simulations at Georgia Tech

    Science.gov (United States)

    Haas, Roland

    2009-05-01

    Mixed compact object binaries consisting of a black hole and a neutron star are expected to be not only one of the primary sources of gravitational radiation to be observed by interferometric detectors but also the central engine of short gamma-ray bursts. We report on the status of our effort at Georgia Tech to model these mixed binary systems using the moving puncture method. The results are obtained with an enhanced version our vacuum MayaKranc code coupled to the hydrodynamics Whisky code. We present preliminary results of gravitational waveforms and the disruption of the neutron star for simple polytropic equations of state.

  7. Come and see our new high-tech products!

    CERN Multimedia

    GS Department

    2010-01-01

    Since 1977, GMP has been active in the fields of laser, spectroscopy, electro-optics and micropositioning. Its mission is to link between suppliers of high tech products with the end users. On Wednesday 26 May between 10 and 12 a.m. - Room A, Main Building, (Bldg. 61/1-017) - you will be able to touch and try out our new laser products. Our specialized engineers will also be on hand to answer all your questions. A drink will be offered at the end of the presentation. There will also be the opportunity to plan meetings in the afternoon to further discuss and complicated questions.

  8. Development of a data capture tool for researching tech entrepreneurship

    DEFF Research Database (Denmark)

    Andersen, Jakob Axel Bejbro; Howard, Thomas J.; McAloone, Tim C.

    2014-01-01

    Startups play a crucial role in exploiting the commercial advantages created by new, advanced technologies. Surprisingly, the processes by which the entrepreneur commercialises these technologies are largely undescribed - partly due to the absence of appropriate process data capture tools....... This paper elucidates the requirements for such tools by drawing on knowledge of the entrepreneurial phenomenon and by building on the existing research tools used in design research. On this basis, the development of a capture method for tech startup processes is described and its potential discussed....

  9. Hi-Tech Skills Anticipation for Sustainable Development in Russia

    Directory of Open Access Journals (Sweden)

    Valery Gurtov

    2014-12-01

    Full Text Available It is evident that there is a heightened importance in Russia attributed to ensuring that students develop skills, which will enable them to be more productive and engaged citizens. This article deals with a skills anticipation methodology for seven hi-tech industries in Russia that resulted in the development of models for both soft and hard skills. There is a variety of widely applied methods – qualitative projection of labor market parameters, desk studies, documents analysis, foresight sessions, employers' and experts' surveys. As a result, new skills models are to help the specialists to effectively overcome the challenges, apply innovative decisions, and increase their technological knowledge.

  10. Pudong:Building a Hi-tech Platform

    Institute of Scientific and Technical Information of China (English)

    LiJialin; WuXinyi

    2003-01-01

    The approach of the knowledge economy means that Shanghai-China's most international city-is advancing towards world metropolis status.As the Chinese saying goes, “In the north is Zhongguancun,and in the south is Zhangjiangyuan.”In order to promote their respective economic growth,both Beijing and Shanghai focus on high technologies.Their importance,as represented by the Zhangjiang Hi-tech Park,is daily becoming more prominent in Pudong,and consequently,the whole of Shanghai.

  11. 78 FR 52535 - Withdrawal of Approval of New Animal Drug Applications; Quali-Tech Products, Inc.; Bambermycins...

    Science.gov (United States)

    2013-08-23

    ...; Quali- Tech Products, Inc.; Bambermycins; Pyrantel; Tylosin; Virginiamycin AGENCY: Food and Drug... feeds, are no longer manufactured or marketed: NADA 097-980 for Quali-Tech TYLAN-10 (tylosin...

  12. Construction of Innovative Rural Sci-tech Service System in China

    Institute of Scientific and Technical Information of China (English)

    Xinyue; LI; Qiwei; DAI

    2013-01-01

    At the background of structural regulation of agriculture and industrialized development of rural areas,systematic thought and constructive recommendations are put forward on building innovative rural sci-tech service system in China from following 5 aspects. (1) In organizational system,rural sci-tech service associations should become nonprofit organizations that have independent legal entities. (2) In service object,it should take farmers as subject,new rural economic organizations as carrier,agricultural leading enterprises as handle,little village officials as joint,sci-tech special commissioner as link,and agricultural brokers as medium. (3) In information resources,it should enhance practicality construction and sharing. (4) In service methods and reform measures,it should combine information technology,expert technical consulting service,and sci-tech model base. (5) In policy support and input mechanism,it should follow the principle of diversification,set up government special funds,and formulate preferential policies to attract sci-tech talents to join in rural sci-tech services,and protect legal rights and interests of sci-tech personnel in rural sci-tech services.

  13. Do gender and personality traits (BFI-10) influence self-perceived tech savviness?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek

    2015-01-01

    Nowadays, it is necessary to use technology in various everyday activities. A certain level of what used to be called high-tech savviness is needed to access certain services. The aim of this paper is to analyze if gender and personality traits (Big Five Inventory-10) influence self-perceived tech...

  14. A Decision Support System for Identification and Evaluation of High-tech Products

    Institute of Scientific and Technical Information of China (English)

    GAO Chang-yuan; LIANG Jing-guo; CAO Xiu-ying

    2002-01-01

    According to high-tech product features and decision support system theory, a decision support system (DSS) for identification and evaluation of high-tech products has been designed which consists of the user interface subsystem, the data management subsystem, the model management subsystem and the knowledge management subsystem. This paper describes the function and the framework of the system.

  15. State of FinTech in Europe: Mutation perspectives of the banking sector

    OpenAIRE

    Marasco, Marco

    2017-01-01

    This paper studies the relationship between FinTech start-ups and the banking sector. The aim is to assess the impact that the FinTech sector might have on the business model and profitability of banks. Master [120] en sciences de gestion (Mons), Université catholique de Louvain, 2017

  16. When High Tech ceases to be High Growth: The Loss of Dynamism of the Cambridgeshire Regio

    NARCIS (Netherlands)

    Stam, E.; Martin, R.

    2012-01-01

    This paper analyses mechanisms of decline and renewal in high-tech regions, illustrated with empirical evidence on the Cambridgeshire high-tech region in the UK. The paper contributes to ecological (‘carrying capacity’) and evolutionary (path dependence) theories of regional development. It provides

  17. GATE Center for Automotive Fuel Cell Systems at Virginia Tech

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Douglas [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2011-09-30

    The Virginia Tech GATE Center for Automotive Fuel Cell Systems (CAFCS) achieved the following objectives in support of the domestic automotive industry: Expanded and updated fuel cell and vehicle technologies education programs; Conducted industry directed research in three thrust areas development and characterization of materials for PEM fuel cells; performance and durability modeling for PEM fuel cells; and fuel cell systems design and optimization, including hybrid and plug-in hybrid fuel cell vehicles; Developed MS and Ph.D. engineers and scientists who are pursuing careers related to fuel cells and automotive applications; Published research results that provide industry with new knowledge which contributes to the advancement of fuel cell and vehicle systems commercialization. With support from the Dept. of Energy, the CAFCS upgraded existing graduate course offerings; introduced a hands-on laboratory component that make use of Virginia Tech's comprehensive laboratory facilities, funded 15 GATE Fellowships over a five year period; and expanded our program of industry interaction to improve student awareness of challenges and opportunities in the automotive industry. GATE Center graduate students have a state-of-the-art research experience preparing them for a career to contribute to the advancement fuel cell and vehicle technologies.

  18. Study on Management System for Agricultural Sci-tech Achievement Transformation Funding Project

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Hong; YU; Jun

    2013-01-01

    Relying on the management system for agricultural sci-tech achievement transformation funding project in Zhejiang Province, on the basis of current situations and demand of agricultural sci-tech achievement transformation funding project management system, we present a B/S-structured and J2EE platform-based system which adopts MVC mode and integrates mainstream open-source frame technologies such as Spring, Struts2, ExtJs, TopLink and FreeMarker, etc. Practice has shown that this system provides an original model for management of sci-tech project application, and various projects can be expanded on this model. With the aid of this system, sci-tech project management personnel can be relieved from trivial manual works, so as to increase working efficiency and improve management level of sci-tech project management.

  19. Competitive low-tech manufacturing and challenges for regional policy in the European context

    DEFF Research Database (Denmark)

    Hansen, Teis; Winther, Lars

    2014-01-01

    Today, low-tech firms in high-wage countries are focusing on increasing investments in highly skilled labour and advanced machinery, incremental innovation and high value-added niches. Danish policy, however, gives little attention to the new specificities of low-tech manufacturing, and the under....... Conversely, user–producer interactions and machinery investments, which are critical to low-tech competitiveness, are disregarded by policies.......Today, low-tech firms in high-wage countries are focusing on increasing investments in highly skilled labour and advanced machinery, incremental innovation and high value-added niches. Danish policy, however, gives little attention to the new specificities of low-tech manufacturing...

  20. Chem-Prep PZT 95/5 for neutron generator applications : development of laboratory-scale powder processing operations.

    Energy Technology Data Exchange (ETDEWEB)

    Montoya, Ted V.; Moore, Roger Howard; Spindle, Thomas Lewis Jr.

    2003-12-01

    Chemical synthesis methods are being developed as a future source of PZT 95/5 powder for neutron generator voltage bar applications. Laboratory-scale powder processes were established to produce PZT billets from these powders. The interactions between calcining temperature, sintering temperature, and pore former content were studied to identify the conditions necessary to produce PZT billets of the desired density and grain size. Several binder systems and pressing aids were evaluated for producing uniform sintered billets with low open porosity. The development of these processes supported the powder synthesis efforts and enabled comparisons between different chem-prep routes.

  1. OligoPrep PVA support for oligonucleotide synthesis in columns on a scale up to 10 micromol.

    Science.gov (United States)

    Aitken, Sheena; Anderson, Emma

    2007-01-01

    OligoPrep is a macroporous polyvinylacetate (PVA) biodegradable support that has been designed for cost-effective automated synthesis of oligonucleotides using standard phosphoramidite chemistry. Originally developed for large-scale oligonucleotide synthesis in beds and reactors, we present here its utility for medium-scale work of 1-10 micromol in column syntheses on standard DNA synthesizers. We show how an increase in scale, and, therefore, yield, can be achieved without significant increase in reagent quantity. Additional deblock and oxidation cycles can provide high coupling yields, and the use of concentrated ammonia in aqueous methylamine (AMA) for oligonucleotide cleavage and deprotection results in excellent recovery.

  2. Efectos de una dosis baja de bisfenol A sobre el eje reproductor de ratas machos prepúberes

    OpenAIRE

    Gámez, Juan Manuel; Penalba, Romina; Cardoso, Nancy Patricia; Ponzo, Osvaldo Juan; Carbone, Silvia Elena; Pandolfi, Matias; Scacchi, Pablo; Reynoso, Roxana María

    2015-01-01

    El objetivo del presente trabajo fue estudiar el efecto de una dosis baja de bisfenol A (BPA) sobre el eje reproductor de ratas macho prepúberes, expuestas durante la gestación y la lactancia. Se trató a ratas hembra preñadas con una dosis aproximada de exposición de BPA de 3 mg, administrado en el agua de bebida, y el tratamiento continuó durante la lactancia. Las crías macho fueron sacrificadas a los 35 días de vida, etapa prepuberal. Se evaluó el peso corporal durante el desarrollo de las...

  3. "I did not want to give birth to a child who has HIV": Experiences using PrEP during pregnancy among HIV-uninfected Kenyan women in HIV-serodiscordant couples.

    Science.gov (United States)

    Pintye, Jillian; Beima-Sofie, Kristin M; Kimemia, Grace; Ngure, Kenneth; Trinidad, Susan Brown; Heffron, Renee; Baeten, Jared; Odoyo, Josephine; Mugo, Nelly; Bukusi, Elizabeth A; Kelley, Maureen C; John-Stewart, Grace C

    2017-07-31

    The perceptions, motivations, and beliefs of HIV-uninfected women about PrEP use during pregnancy can influence its uptake and adherence. This study elicited the views of HIV-uninfected women with personal experience taking PrEP during pregnancy. Qualitative interviews were conducted with HIV-uninfected women who had personal experience taking PrEP while pregnant. Semi-structured interviews were conducted with 21 HIV-uninfected Kenyan women in HIV-serodiscordant couples enrolled in an open-label PrEP demonstration project who became pregnant while using PrEP and continued PrEP through their pregnancy. Interviews were audio-recorded and transcribed into English. A qualitative descriptive analysis was performed, using a constant comparison approach to identify key themes related to PrEP use in pregnancy. Desire to remain HIV-uninfected and have an HIV-free infant were strong motivators influencing continued use of PrEP during pregnancy. Supporting HIV-infected partners and childbearing within an HIV-serodiscordant relationship were also motivators. Women had challenges distinguishing normal pregnancy symptoms from PrEP side effects and were concerned that observed side effects could be signs of danger for the infant related to PrEP exposure. Healthcare providers were important conduits of knowledge about PrEP, and continuity of PrEP providers throughout pregnancy facilitated adherence. HIV-uninfected women in HIV-serodiscordant couples were motivated to use PrEP during pregnancy to remain HIV-uninfected and to have an HIV-free child, but had concerns about side effects. Healthcare providers will be important for PrEP messaging and adherence support in this unique population.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without

  4. Intimate Partner Violence and Adherence to HIV Pre-exposure Prophylaxis (PrEP) in African Women in HIV Serodiscordant Relationships: A Prospective Cohort Study.

    Science.gov (United States)

    Roberts, Sarah T; Haberer, Jessica; Celum, Connie; Mugo, Nelly; Ware, Norma C; Cohen, Craig R; Tappero, Jordan W; Kiarie, James; Ronald, Allan; Mujugira, Andrew; Tumwesigye, Elioda; Were, Edwin; Irungu, Elizabeth; Baeten, Jared M

    2016-11-01

    Intimate partner violence (IPV) is associated with higher HIV incidence, reduced condom use, and poor adherence to antiretroviral therapy and other medications. IPV may also affect adherence to pre-exposure prophylaxis (PrEP). We analyzed data from 1785 HIV-uninfected women enrolled in a clinical trial of PrEP among African HIV serodiscordant couples. Experience of verbal, physical, or economic IPV was assessed at monthly visits by face-to-face interviews. Low PrEP adherence was defined as clinic-based pill count coverage <80% or plasma tenofovir levels <40 ng/mL. The association between IPV and low adherence was analyzed using generalized estimating equations, adjusting for potential confounders. In-depth interview transcripts were examined to explain how IPV could impact adherence. Sixteen percent of women reported IPV during a median of 34.8 months of follow-up (interquartile range 27.0-35.0). Overall, 7% of visits had pill count coverage <80%, and 32% had plasma tenofovir <40 ng/mL. Women reporting IPV in the past 3 months had increased risk of low adherence by pill count (adjusted risk ratio 1.49, 95% confidence interval: 1.17 to 1.89) and by plasma tenofovir (adjusted risk ratio 1.51, 95% confidence interval: 1.06 to 2.15). Verbal, economic, and physical IPV were all associated with low adherence. However, the impact of IPV diminished and was not statistically significant 3 months after the reported exposure. In qualitative interviews, women identified several ways in which IPV affected adherence, including stress and forgetting, leaving home without pills, and partners throwing pills away. Women who reported recent IPV in the Partners PrEP Study were at increased risk of low PrEP adherence. Strategies to mitigate PrEP nonadherence in the context of IPV should be evaluated.

  5. a Study on the Document Information Service of the National Agricultural Library for Agricultural Sci-Tech Innovation in China

    Science.gov (United States)

    Xu, Qian; Meng, Xianxue

    This paper presents the significant function of the Chinese National Agricultural Library (CNAL) in the agricultural sci-tech innovation system in China, analyses the development of collection and service in the CNAL, explores the challenge towards sustain and develop information services for the agricultural sci-tech research and innovation, at last proposes the strategy for sci-tech document information service development.

  6. 75 FR 21663 - Maysteel, LLC Including On-Site Leased Workers From Staff One, Badger Tech, Boyd Hunter, Seek...

    Science.gov (United States)

    2010-04-26

    ... Tech, Boyd Hunter, Seek, QPS, and Service First, Menomonee Falls, WI; Amended Certification Regarding..., including on-site leased workers from Staff One, Badger Tech, Boyd Hunter, Seek, and QPS, Menomonee Falls... Maysteel, LLC, including on-site leased workers from Staff One, Badger Tech, Boyd Hunter, Seek, QPS,...

  7. High-Tech Means High-Efficiency: The Business Case for EnergyManagement in High-Tech Industries

    Energy Technology Data Exchange (ETDEWEB)

    Shanshoian, Gary; Blazek, Michele; Naughton, Phil; Seese, RobertS.; Mills, Evan; Tschudi, William

    2005-11-15

    In the race to apply new technologies in ''high-tech'' facilities such as data centers, laboratories, and clean rooms, much emphasis has been placed on improving service, building capacity, and increasing speed. These facilities are socially and economically important, as part of the critical infrastructure for pharmaceuticals,electronics, communications, and many other sectors. With a singular focus on throughput, some important design issues can be overlooked, such as the energy efficiency of individual equipment (e.g., lasers, routers and switches) as well as the integration of high-tech equipment into the power distribution system and the building envelope. Among technology-based businesses, improving energy efficiency presents an often untapped opportunity to increase profits, enhance process control,maximize asset value, improve the work place environment, and manage a variety of business risks. Oddly enough, the adoption of energy efficiency improvements in this sector lags behind many others. As a result, millions of dollars are left on the table with each year ofoperation.

  8. The Cobas AmpliPrep/Cobas TaqMan HCV Test, Version 2.0, Real-Time PCR Assay Accurately Quantifies Hepatitis C Virus Genotype 4 RNA

    OpenAIRE

    Chevaliez, Stéphane; Bouvier-Alias, Magali; Rodriguez, Christophe; Soulier, Alexandre; Poveda, Jean-Dominique; Pawlotsky, Jean-Michel

    2013-01-01

    Accurate hepatitis C virus (HCV) RNA quantification is mandatory for the management of chronic hepatitis C therapy. The first-generation Cobas AmpliPrep/Cobas TaqMan HCV test (CAP/CTM HCV) underestimated HCV RNA levels by >1-log10 international units/ml in a number of patients infected with HCV genotype 4 and occasionally failed to detect it. The aim of this study was to evaluate the ability of the Cobas AmpliPrep/Cobas TaqMan HCV test, version 2.0 (CAP/CTM HCV v2.0), to accurately quantify H...

  9. School of the Arts seeks arts organizations and artists for participation in ArtsFusion 2008

    OpenAIRE

    Adams, Louise

    2008-01-01

    Virginia Tech School of the Arts announces ArtsFusion 2008, a weeklong celebration of the arts throughout the New River Valley scheduled for April 12 through April 19. ArtsFusion 2008 is seeking participation by arts organizations and artists both on campus and throughout the New River Valley working in music, film, theatre, dance, creative writing, and the visual arts.

  10. Three High-Tech High Seniors Join the Alia Expedition to Samoa: Science and Science Education

    Science.gov (United States)

    English, B.; Delaney, R.; Staudigel, D.; Staudigel, H.; Koppers, A.; Hart, S.

    2005-12-01

    Three high school seniors from High Tech High (HTH) participated in the ALIA expedition that explored the Samoan hot spot track through seafloor mapping, rock sampling and the study of the water column above an active submarine volcano. The primary responsibility of the HTH participants focused on outreach and education, but they also were substantively involved in all scientific aspects of the cruise. Education and outreach activities included: maintaining the cruise website,the creation of ERESE digital library resources for earth science education, live video-conferences with students half a world away in San Diego, and offering tours of the Research Vessel Kilo Moana during an open house event organized with the Samoa Department of Eduation. At this occasion, the HTH seniors shared experiences and knowledge with the visiting Samoan elementary and high school students. Science involvement of the high school seniors included deck and laboratory work, by assisting with dredging, piston coring, rock cataloguing, casting CTDs, and computer programming. Three major computer programming efforts by the HTH seniors substantively supported the outreach activities and the science operations during ALIA. (1) The development of "CustomHTMLExport", a utility that allows for the export of photographs and their metadata into web pages and digital library collection. (2) The "CruiseWatch" featureson the ALIA website (http://earthref.org/ERESE/projects/ALIA/) that displays in near - real time key shipboard data such as the location on a map, geographic coordinates, ship speed, direction and wind speed and dredging data. (3) A dredge location simulator to predict the location of the dredge with respect to the ship and the seafloor which was made necessary for the safety of dredging due to the failure of pingers that normally are used to provide critical data for the location of the dredge with respect to the seafloor. The dredge location model is based a fluid dynamics approach

  11. Petascale Simulation Initiative Tech Base: FY2007 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    May, J; Chen, R; Jefferson, D; Leek, J; Kaplan, I; Tannahill, J

    2007-10-26

    The Petascale Simulation Initiative began as an LDRD project in the middle of Fiscal Year 2004. The goal of the project was to develop techniques to allow large-scale scientific simulation applications to better exploit the massive parallelism that will come with computers running at petaflops per second. One of the major products of this work was the design and prototype implementation of a programming model and a runtime system that lets applications extend data-parallel applications to use task parallelism. By adopting task parallelism, applications can use processing resources more flexibly, exploit multiple forms of parallelism, and support more sophisticated multiscale and multiphysics models. Our programming model was originally called the Symponents Architecture but is now known as Cooperative Parallelism, and the runtime software that supports it is called Coop. (However, we sometimes refer to the programming model as Coop for brevity.) We have documented the programming model and runtime system in a submitted conference paper [1]. This report focuses on the specific accomplishments of the Cooperative Parallelism project (as we now call it) under Tech Base funding in FY2007. Development and implementation of the model under LDRD funding alone proceeded to the point of demonstrating a large-scale materials modeling application using Coop on more than 1300 processors by the end of FY2006. Beginning in FY2007, the project received funding from both LDRD and the Computation Directorate Tech Base program. Later in the year, after the three-year term of the LDRD funding ended, the ASC program supported the project with additional funds. The goal of the Tech Base effort was to bring Coop from a prototype to a production-ready system that a variety of LLNL users could work with. Specifically, the major tasks that we planned for the project were: (1) Port SARS [former name of the Coop runtime system] to another LLNL platform, probably Thunder or Peloton (depending

  12. Percentage recovery of dioxin homologue through power-prep according to the eluting solvents and their amounts

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Tae-Uk [Gyeongsang National Univ., Jinju (Korea). Division of Applied Life Science]|[National Veterinary Research and Quarantine Service (Korea). Busan Regional Office; Kim, Dong-Gyu [National Veterinary Research and Quarantine Service (Korea). Seoul Regional Office; Choi, Si-Weon [National Veterinary Research and Quarantine Service (Korea). Busan Regional Office; Seo, Dong-Cheol; Jeo, Jong-Soo [Gyeongsang National Univ., Jinju (Korea). Division of Applied Life Science; Lee, Hong-Jae [Jinju National Univ. (Korea). Dept. of Environmental Engineering

    2004-09-15

    Because of the persistence and accumulation of polychlorinated dibenzo dioxins(PCDDs) and polychlorinated dibenzo furans(PCDFs) in the environment, dioxins contamination is regarded as a global issue. And various methods for analyzing PCDDs and PCDFs have been developed and improved. According to US EPA method, cleanup method was very various. Conventional cleanup methods are very dependable, but are time consuming and use large volumes of organic solvents. To increase the efficiency of cleanup for the analysis of PCDDs and PCDFs, we used high speed automated sample cleanup system for dioxins which is called Power-Prep trademark (Fluid Management System Inc., USA). Power- Prep trademark gave us swift analysis of dioxin and its precision and accuracy. This system was designed to cleanup of toxic compound such as dioxins, PCBs, pesticides and PAHs using silica, alumina and carbon column. Using this system, it is possible to conduct several samples in less than 1.5 hours, thereby, achieving high recoveries and excellent precision and accuracy for all dioxin congeners. In this experiment, we carried out PCDDs and PCDFs analysis by FMS(Fluid Management System Inc.) with 3 eluting solvents such as toluene, hexane and dichloromethane to find out the best eluting solvent and its amounts.

  13. Advanced Polymeric Materials for High-tech Innovations

    Institute of Scientific and Technical Information of China (English)

    TANG; BenZhong

    2001-01-01

    High technology is advancing our society and modernizing our life and advanced materials play an important role in the technological innovations. My research group has been working on the development of advanced polymeric materials and in this talk I will report our recent work on the creation of new conjugated polymers with novel molecular structures and unique materials properties.1-18 Our work include the design of molecular structures of monomeric building blocks, development of stable, effective and environmentally benign "green” polymerization catalysts, discovery of new polymerization reactions, synthesis of functional macromolecules, fabrication of nanodimensional composites, assembly and control of hierarchical structures, and construction of electrooptical devices. We have revealed the liquid crystallinity, light emission, photoconductivity, optical limiting, nano-hybridization, solvatochromism, optical activity, self-organization, and biological activity of the linear polyacetylenes and hyperbranched polyarylenes. The utilization of the advanced polymers and their interesting materials properties for high-tech innovations will be discussed.  ……

  14. Knowledge acquisition and creation in the high-tech industry

    Directory of Open Access Journals (Sweden)

    Juliano Pavanelli Stefanovitz

    2007-10-01

    Full Text Available This paper explores the new challenges that come with the emergence of knowledge-based approaches on organizational studies. It is widely recognized, in this context, the increasing importance of understanding the processes through which companys acquire, storage, disseminate and create knowledge. This research analysis the knowledge creation and external acquisition processes in the high-tech industry, environment in which intensive use of knowledge is made. For that, it presents a case study of an R&D Division of a company present in the industrial automation market. In recognition of its innovative competence, this company won the FINEP Prize – Technological Innovation. In this study, besides the identification of the main external knowledge sources, an analysis of the knowledge types conversion observed in its product development activities is made.

  15. Power quality in high-tech campus: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Moreno-Munoz, A.; Redel, M.; Gonzalez, M. [Universidad de Cordoba (Spain). Departamento de Electrotecnia y Electronica

    2006-07-01

    This paper presents preliminary results from a power-quality audit conducted at a high-tech campus over the last year. Voltage and current were measured at various R and D buildings; it was found that the main problems for the equipment installed were voltage sags and surges. The paper examines the causes and effects of power disturbances that affect computer or any other microprocessor-based equipment and analyses the auto-protection capabilities of modern power supplies. The convenience of 'enhanced power supply' or 'low-cost customer-side' protection solutions is also discussed. Finally, it addresses the role of the standards on the protection of electronic equipment and the implications for the final customer. (author)

  16. Advanced Polymeric Materials for High-tech Innovations

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@ High technology is advancing our society and modernizing our life and advanced materials play an important role in the technological innovations. My research group has been working on the development of advanced polymeric materials and in this talk I will report our recent work on the creation of new conjugated polymers with novel molecular structures and unique materials properties.1-18 Our work include the design of molecular structures of monomeric building blocks, development of stable, effective and environmentally benign "green” polymerization catalysts, discovery of new polymerization reactions, synthesis of functional macromolecules, fabrication of nanodimensional composites, assembly and control of hierarchical structures, and construction of electrooptical devices. We have revealed the liquid crystallinity, light emission, photoconductivity, optical limiting, nano-hybridization, solvatochromism, optical activity, self-organization, and biological activity of the linear polyacetylenes and hyperbranched polyarylenes. The utilization of the advanced polymers and their interesting materials properties for high-tech innovations will be discussed.

  17. Hi-tech products marketing and competitive advantage

    Directory of Open Access Journals (Sweden)

    Perović Jelena

    2004-01-01

    Full Text Available The company today, in causes turbulent environment and intensive integrations must cooperate, accept and develop high technology in order to achieve needs of customers. It's only way that companies replay on challenge global environment, decrease costs of investment per capita, decrease the risk, captivate new market and held competitive in causes of global market. High tech technology marketing function is help that results of new technology transfer on economy. Their function is reach need of customers, too. Positive influence of technology is the highest in area of production costs and productivity. Speed years are in front of our and it demands larger productivity, which primary source must be technology changes. High technology marketing is the most provocative framework for take competitive advantage, answer on global change and way of permanent reach rigorous need of customers.

  18. Emerging technologies in ANC at VAL-Virginia Tech

    Science.gov (United States)

    Johnson, Marty; Fuller, Chris; Homma, Kenji

    2003-10-01

    This presentation will overview the development and application of three new active noise control technologies at VAL-Virginia Tech. Distributed Active Vibration Absorbers (DAVAs) consist of large area spring elements with embedded active elements and covered with a dynamic mass layer. Development of conformal DAVAs and their application to noise control in aircraft and launch vehicle fairings will be overviewed. New work in applying active control techniques to developing virtual acoustic systems and its application to virtual prototyping and virtual reality applications will be discussed. The development a modular, compact active noise control duct which utilizes very small active sources, transducers and a cost effective controller to reducing the total radiated sound from small fans will be presented. The application of the modular ANC duct to a small computer cooling fan will be presented.

  19. Research on the competitiveness of high-tech industries in northeast China

    Science.gov (United States)

    Liu, Lei; Wang, Yang; Wang, Ming-Quan; Xiao, Yan-Bo; Gao, Ming

    2017-06-01

    Based on characteristics of high-tech industry in Northeast China, high-tech industry competitiveness index system was developed, and the competitiveness of high-tech industry was evaluated through principal component analysis and location quotient method. The results showed that the scale of high-tech industry in Northeast China as a whole was small, and presented a decreasing trend for the proportion in the country. The competitiveness of high-tech industry in Northeast China lagged far behind that of the eastern and central regions. The high-tech industry competitiveness of Liaoning, Jilin and Heilongjiang provinces in China ranked 15, 19 and 21, respectively. The manufacture of medicine in Jilin province, and the manufacture of aircraft and spacecraft and the related equipment in Liaoning and Heilongjiang provinces had high competitive advantage, but the manufacture of electronic equipment and communication equipment and the manufacture of computers and office equipment was lack of competitiveness. The development suggestions were put forward to improve the competitiveness of high-tech industries in Northeast China.

  20. Several Theoretical Issues on Agricultural Sci-tech Service and Management

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    In view of particularity and complexity of agricultural sci-tech service and management,this paper presents definition of basic concept of agricultural sci-tech service and management,sums up its basic characteristics,and discusses and analyzes its structural elements and functions. The agricultural sci-tech service and management plays an important role in speeding up rural construction and narrowing the gap between urban and rural areas. It ensures benign cycle of scientific and technological achievements and regional environment,and promotes development of agricultural industrialization.

  1. [The development of strategic management of high-tech surgical medical care].

    Science.gov (United States)

    Nechaev, V S; Krasnov, A V

    2013-01-01

    The high-tech surgical medical care is one of the most effective types of medical care in Russia. However high-tech surgical treatment very often is inaccessible for patients. The development of basics of strategic management of high-tech surgical care makes it possible to enhance availability of this type of care and to shorten the gap between volumes of rendered care and population needs. This approach can be resulted in decrease of disability and mortality of the most prevalent diseases of cardio-vascular diseases, malignant neoplasms, etc. The prerequisites can be developed to enhance life quality and increase longevity of population.

  2. The FinTech phenomenon: antecedents of financial innovation perceived by the popular press

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    The financial industry has been strongly influenced by digitalization in the past few years reflected by the emergence of “FinTech,” which represents the marriage of “finance” and “information technology.” FinTech provides opportunities for the creation of new services and business models and poses challenges to traditional financial service providers. Therefore, FinTech has become a subject of debate among practitioners, investors, and researchers and is highly visible in the popular media. ...

  3. The People's Republic of China's high-tech exports: Myth and reality

    OpenAIRE

    Xing, Yuqing

    2012-01-01

    Trade statistics portray the People's Republic of China (PRC) as the largest exporter of high-tech products. In this paper I will argue that the PRC's leading position in high-tech exports is a myth created by outdated trade statistics which are inconsistent with trade based on global supply chains. Current trade statistics mistakenly credit entire values of assembled high-tech products to the PRC, thus greatly inflating its exports. In 2009, the PRC's value-added accounted for only about 3% ...

  4. China s Imp.& Exp.of New and High-tech Products

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Import of New and High-tech Products Increases Rapidly The proportion of new and high-tech products in the total import continues to increase.Ever since 1991,the proportion of new and high-tech products in the total import has experienced a continuous growth.It took up only 14.8% of the total import in 1991.The figure reached 20.8% in 1998,and further rose to that of 26.3% in 2001.From January to June this year,the import of new and hightech products totaled 34.540 billion USD,up 18.1% over the same per...

  5. Is there a large-country advantage in high-tech?

    OpenAIRE

    Jan Fagerberg

    1995-01-01

    High-tech is a commonly used catch-word for industries that use a relatively large share of their resources on R&D and develop many new products and processes. It is a widely held view that high- tech is good for growth, and that countries that succeed in high- tech industry perform well. Schumpeterian theory, as well as the more recent “new growth” theories, are often quoted in support of this view. However, the “new growth” theories also suggest that large countries are more likely than sma...

  6. Baza danych BazTech – integracja i poszerzanie dostępu

    OpenAIRE

    2014-01-01

    The BazTech database – integration and widening access. The BazTech base enables the access to scientific publications in Polish journals in the field of technical sciences, and as one of the resources of open science is available at the Virtual Library of Science. The paper presents the current state of BazTech as an introduction to the review of the development of the base in the direction of integration with other resources. Integration – apart from multibrowsers (eg PRIMO), data aggregato...

  7. The FinTech phenomenon: antecedents of financial innovation perceived by the popular press

    OpenAIRE

    Zavolokina, Liudmila; Dolata, Mateusz; Schwabe, Gerhard

    2016-01-01

    The financial industry has been strongly influenced by digitalization in the past few years reflected by the emergence of “FinTech,” which represents the marriage of “finance” and “information technology.” FinTech provides opportunities for the creation of new services and business models and poses challenges to traditional financial service providers. Therefore, FinTech has become a subject of debate among practitioners, investors, and researchers and is highly visible in the popular media. ...

  8. SkTech:俄罗斯工程教育的模式创新%SkTech: An Innovative Model of Engineering Education in Russia

    Institute of Scientific and Technical Information of China (English)

    孔寒冰; 吴婧姗; 李文

    2012-01-01

    The Skolkovo Institute of Science and Technology(SkTech) is a new Russian research university in an international context built in Skolkovo recently.With the participation and support of MIT,it provides graduate programs in science and engineering.This paper briefly describes profound context of SkTech,Innovation Entrepreneurship(IE) ideas and practice,novel organization and culture,and the unique development model as well.It is worthwhile to notice that SkTech innovation mode is a triple helix of integrating Research-Education-IE.This also represents the important essence of SkTech innovative model and its key role in Skolkovo innovation ecosystem.%俄罗斯的SkTech(斯科尔科沃理工学院)是在MIT的鼎力支持下新近创办的一所理工科研究生大学。本文简要介绍它的建校背景、先进的办学理念、新颖的组织架构与文化,以及独特的办学模式与实践。SkTech创新模式的精彩之处,在于它的"研究、教育、创业创新"三重螺旋集成的协同创新。这也是Sk-Tech将在斯科尔科沃创新生态系统中发挥关键作用的重要机制。

  9. Access to Basic HIV-Related Services and PrEP Acceptability among Men Who Have sex with Men Worldwide: Barriers, Facilitators, and Implications for Combination Prevention

    Directory of Open Access Journals (Sweden)

    George Ayala

    2013-01-01

    Full Text Available Introduction. Men who have sex with men (MSM are disproportionately impacted by HIV globally. Easily accessible combination HIV prevention strategies, tailored to the needs of MSM, are needed to effectively address the AIDS pandemic. Methods and Materials. We conducted a cross-sectional study among MSM (n=3748 from 145 countries from April to August 2012. Using multivariable random effects models, we examined factors associated with acceptability of preexposure prophylaxis (PrEP and access to condoms, lubricants, HIV testing, and HIV treatment. Results. Condoms and lubricants were accessible to 35% and 22% of all respondents, respectively. HIV testing was accessible to 35% of HIV-negative respondents. Forty-three percent of all HIV-positive respondents reported that antiretroviral therapy was easily accessible. Homophobia, outness, and service provider stigma were significantly associated with reduced access to services. Conversely, community engagement, connection to gay community, and comfort with service providers were associated with increased access. PrEP acceptability was associated with lower PrEP-related stigma, less knowledge about PrEP, less outness, higher service provider stigma, and having experienced violence for being MSM. Conclusions. Ensuring HIV service access among MSM will be critical in maximizing the potential effectiveness of combination approaches, especially given the interdependence of both basic and newer interventions like PrEP. Barriers and facilitators of HIV service access for MSM should be better understood and addressed.

  10. Comparing SurePath, ThinPrep, and conventional cytology as primary test method: SurePath is associated with increased CIN II+ detection rates

    NARCIS (Netherlands)

    K. Rozemeijer (Kirsten); C. Penning (Corine); A.G. Siebers (Albertus); S.K. Naber (Steffie); S.M. Matthijsse (Suzette); M. van Ballegooijen (Marjolein); F.J. van Kemenade (Folkert); I.M.C.M. de Kok (Inge)

    2016-01-01

    textabstractPurpose: Within the last decade, SurePath and ThinPrep [both liquid-based cytology (LBC) tests] have replaced conventional cytology (CC) as primary test method in cervical cancer screening programs of multiple countries. The aim of our study was to examine the effect in the Dutch screeni

  11. "Get a Blue and You Will See Your Money Back Again": Staffing and Marketing the English Prep School, 1890-1912

    Science.gov (United States)

    Benson, John

    2014-01-01

    This article explores the ways in which English prep schools were staffed and marketed in the years before the First World War. Its aim more specifically is to employ a biographical approach to consider the emphasis that the schools placed upon sport, and in particular the extent to which they recruited Oxford and Cambridge Blues as teachers…

  12. Comparing SurePath, ThinPrep, and conventional cytology as primary test method: SurePath is associated with increased CIN II+ detection rates

    NARCIS (Netherlands)

    K. Rozemeijer (Kirsten); C. Penning (Corine); A.G. Siebers (Albertus); S.K. Naber (Steffie); S.M. Matthijsse (Suzette); M. van Ballegooijen (Marjolein); F.J. van Kemenade (Folkert); I.M.C.M. de Kok (Inge)

    2016-01-01

    textabstractPurpose: Within the last decade, SurePath and ThinPrep [both liquid-based cytology (LBC) tests] have replaced conventional cytology (CC) as primary test method in cervical cancer screening programs of multiple countries. The aim of our study was to examine the effect in the Dutch screeni

  13. Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

    Science.gov (United States)

    Rebolj, Matejka; Rask, Johanne; van Ballegooijen, Marjolein; Kirschner, Benny; Rozemeijer, Kirsten; Bonde, Jesper; Rygaard, Carsten; Lynge, Elsebeth

    2015-01-01

    Background: We compared the sensitivity and specificity of liquid-based cytology (LBC) and computer-assisted reading for SurePath/FocalPoint and ThinPrep with those of manually read conventional cytology in routine cervical screening in four Danish laboratories. Methods: Using data from five nationwide registers, technological phases were identified by slide preparation, reading technique, and triage of borderline cytology. Trends in the detection of cervical intraepithelial neoplasia (CIN) were an indicator of the technology's relative sensitivity, and trends in false-positive tests an indicator of relative specificity. Results: At 23–29 years, SurePath/FocalPoint statistically significantly increased the detection of ⩾CIN3 by 85% compared with manually read conventional cytology. The 11% increase with ThinPrep was not significant. At 30–44 years, the increase with SurePath/FocalPoint was 58% the 16% increase with ThinPrep was not significant. At 45–59 years, both technologies led to nonsignificant decreases in the detection. SurePath/FocalPoint doubled the frequency of false-positive tests at any age. With ThinPrep, these proportions remained the same at 23–29 years, but decreased by two-thirds at 45–59 years. In a fourth laboratory with continuous use of manually read conventional cytology, no such trends were seen. Conclusions: The sensitivity and specificity of modern LBC and computer-assisted reading technologies may be brand- and age-dependent. PMID:26448176

  14. "Get a Blue and You Will See Your Money Back Again": Staffing and Marketing the English Prep School, 1890-1912

    Science.gov (United States)

    Benson, John

    2014-01-01

    This article explores the ways in which English prep schools were staffed and marketed in the years before the First World War. Its aim more specifically is to employ a biographical approach to consider the emphasis that the schools placed upon sport, and in particular the extent to which they recruited Oxford and Cambridge Blues as teachers…

  15. PREFACE: 12th High-Tech Plasma Processes Conference (HTPP-12)

    Science.gov (United States)

    Gleizes, Alain; Ghedini, Emanuele; Gherardi, Matteo; Sanibondi, Paolo; Dilecce, Giorgio

    2012-12-01

    The High-Tech Plasma Processes - 12th European Plasma Conference (HTPP-12) was held in Bologna (Italy) on 24-29 June 2012. The conference series started in 1990 as a thermal plasma conference and gradually expanded to include other topic fields as well. Now the High-Tech Plasma Processes - European Plasma Conference (HTPP) is a bi-annual international conference based in Europe with topics encompassing the whole area of plasma processing science. The aim of the conference is to bring different scientific communities together, facilitate the contacts between science, technology and industry and provide a platform for the exploration of both fundamental topics and new applications of plasmas. Thanks to the efforts of the conference chairman, Professor Vittorio Colombo and of the co-chair, Professor Piero Favia, a well balanced participation from both the communities of thermal and nonthermal plasma researchers was achieved; this resulted in just about 196 attendees from 39 countries, with 8 plenary and 15 invited talks, plus 50 oral and 140 poster contributions. This volume of Journal of Physics: Conference Series gathers papers from regular contributions of HTPP-12; each contribution submitted for publication has been peer reviewed and the Editors are very grateful to the referees for their careful support in improving the original manuscripts. In the end, 39 manuscripts were accepted for publication, covering different topics of plasma processing science: from plasma fundamentals and modelling to source design and process diagnostics, from nanomaterial synthesis to surface modification, from waste treatment to plasma applications in a liquid environment. It is an honour to present this volume of Journal of Physics: Conference Series and we deeply thank the authors for their enthusiastic and high-grade contribution. Finally, we would like to thank the conference chairmen, the members of the steering committee, the international scientific committee, the local

  16. PREFACE: 13th High-Tech Plasma Processes Conference (HTPP-2014)

    Science.gov (United States)

    2014-11-01

    The High-Tech Plasma Processes - 13th European Plasma Conference (HTPP-2014) was held in Toulouse (France) on 22-27 June 2014. The conference series started in 1990 as a thermal plasma conference and has gradually expanded to include other related topics. Now the High-Tech Plasma Processes - European Plasma Conference (HTPP) is an international conference organised in Europe every two years with topics encompassing the whole field of plasma processing science. The aim of the conference is to bring different scientific communities together, to facilitate contacts between science, technology and industry and to provide a platform for the exploration of both the fundamental topics and new applications of plasmas. For this edition of HTPP, as was the case for the last, we have acheived a well balanced participation from the communities of both thermal and non-thermal plasma researchers. 142 people from 17 countries attended the conference with the total number of contributions being 155, consisting of 8 plenary and 8 invited talks plus 51 oral and 88 poster contributions. We have received numerous papers corresponding to the contributions of HTPP-2014 that have been submitted for publication in this volume of Journal of Physics: Conference Series. Each submitted contribution has been peer reviewed (60 referees with at least two reviewing each paper) and the Editors are very grateful to the referees for their careful support in improving the original manuscripts. In total, 52 manuscripts have been accepted for publication covering a range of topics of plasma processing science from plasma fundamentals to process applications through to experiments, diagnostics and modelling. We have grouped the papers into the following 5 topics: - Arc-Materials Interaction and Metallurgy - Plasma Torches and Spraying - Synthesis of Powders and Nanomaterials - Deposition and Surface Treatment - Non-Equilibrium Plasmas We deeply thank the authors for their enthusiastic and high

  17. Introduction of the Thin Prep Imaging System™ (TIS: Experience in a high volume academic practice

    Directory of Open Access Journals (Sweden)

    Chivukula Mamatha

    2007-01-01

    Full Text Available Objective: Since the introduction of the liquid-based ThinPrep testing in 1996, most cytology laboratories across the country have adopted the liquid-based cytology (LBC for Pap test screening. Subsequent to wide-spread adoption of the ThinPrep Pap test, the ThinPrep Imaging System (TIS Cytyc Corp, Marlborough, MA was introduced to improve the accuracy and efficiency of screening interpretation. We report our initial experience with the TIS at Magee Women′s Hospital. We introduced the TIS in December 2004. Methods: The imager assisted Pap test results over the first 12 months (December 2004 to December 2005 of implementation were reviewed and analyzed. Our implementation protocol included each cytotechnologist manually prescreening 200 negative slides to gain experience with the imager slides and serve as a quality check for the TIS. We re-screened 3400 slides (200 slides each for 17 cytotechnologists manually which were initially determined to be negative using the TIS. 104,457 Pap tests were imaged on the TIS. 95,899 manually screened Pap tests, 12 months prior to the introduction of the TIS (December 2003-November 2004 are taken as the historic control group for our study. Results :The mean ASC-US rate employing the automated imager was 8.70% [9088/104,457]. The mean LSIL detection rate was 4.22% [4409/104,457]. The imager did not miss any detectible high-grade lesions during these months, with a HSIL (+ detection rate of 0.68% in comparison to 0.60% by manual screening confirmed by follow-up biopsies. The difference is statistically significant with a p value of 0.022 . The definition of false negative rate for purposes of this study is calculated as the number of false negative cases identified out of number of negatives re-screened. The TIS false negative rate was estimated at 0.012% [4/3400]. Conclusion :The overall performance of the TIS in our lab appears to be highly satisfactory in terms of improving sensitivity in screening

  18. Evaluation of the Illumina(®) Beta Version ForenSeq™ DNA Signature Prep Kit for use in genetic profiling.

    Science.gov (United States)

    Churchill, Jennifer D; Schmedes, Sarah E; King, Jonathan L; Budowle, Bruce

    2016-01-01

    While capillary electrophoresis-based technologies have been the mainstay for human identity typing applications, there are limitations with this methodology's resolution, scalability, and throughput. Massively parallel sequencing (MPS) offers the capability to multiplex multiple types of forensically-relevant markers and multiple samples together in one run all at an overall lower cost per nucleotide than traditional capillary electrophoresis-based methods; thus, addressing some of these limitations. MPS also is poised to expand forensic typing capabilities by providing new strategies for mixture deconvolution with the identification of intra-STR allele sequence variants and the potential to generate new types of investigative leads with an increase in the overall number and types of genetic markers being analyzed. The beta version of the Illumina ForenSeq DNA Signature Prep Kit is a MPS library preparation method with a streamlined workflow that allows for targeted amplification and sequencing of 63 STRs and 95 identity SNPs, with the option to include an additional 56 ancestry SNPs and 22 phenotypic SNPs depending on the primer mix chosen for amplification, on the MiSeq desktop sequencer (Illumina). This study was divided into a series of experiments that evaluated reliability, sensitivity of detection, mixture analysis, concordance, and the ability to analyze challenged samples. Genotype accuracy, depth of coverage, and allele balance were used as informative metrics for the quality of the data produced. The ForenSeq DNA Signature Prep Kit produced reliable, reproducible results and obtained full profiles with DNA input amounts of 1ng. Data were found to be concordant with current capillary electrophoresis methods, and mixtures at a 1:19 ratio were resolved accurately. Data from the challenged samples showed concordant results with current DNA typing methods with markers in common and minimal allele drop out from the large number of markers typed on these

  19. Tech-X发动机及其先进技术分析%Analysis on Tech-X Engine and Its Advance Technology

    Institute of Scientific and Technical Information of China (English)

    李杰; 巨亚斌

    2013-01-01

      Tech-X发动机是GE公司研发的用于超大航程公务机的新一代高涵道比涡扇发动机。本文就Tech-X发动机的性能指标和先进技术创新进行了概括性分析,供相关人士参考。%The Tech-X is a high bypass turbofan engine currently under development by GE Aviation. It is being developed in paral el with the larger CFM International LEAP-X, and includes many similar technologies, like blisks and NOx reducing combustors. GE sees potential in using the engine both on large cabin business jets and regional aircraft, where it wil replace the CF34 in GE's production line.

  20. Virginia Tech Corps of Cadets alumnus Timothy Dillera named Hokie Hero

    OpenAIRE

    Cox, Carrie

    2009-01-01

    Corps of Cadets alumnus Capt. Timothy Dillera, United States Air Force, who received a degree in chemistry from the College of Science in 2003 has been selected as the Hokie Hero for the Virginia Tech versus Boston College football game.

  1. Virginia Tech structural engineer part of a winning design team for unusual corporate headquarters

    OpenAIRE

    Steeves, Sue

    2010-01-01

    The American Institute of Steel Construction has presented a national award to a design team, including a Virginia Tech structural engineer, for its work on a dramatic cantilevered corporate headquarters building in Michigan.

  2. Virginia Tech part of $14 million National Science Foundation nanotechnology grant

    OpenAIRE

    Doss, Catherine

    2008-01-01

    Researchers from geosciences and civil and environmental engineering at Virginia Tech are part of a consortium of four principal universities and five other schools awarded a multi-million dollar grant to study nanotechnology and the environment.

  3. Hi-tech Researches Speed up Scientific and Technological Innovations of CNOOC

    Institute of Scientific and Technical Information of China (English)

    Dong Weiliang; Wang Weiyuan

    2007-01-01

    @@ The scientific and technological development of CNOOC Limited entered a new stage during the Tenth Five-Year Plan period. High-tech researches in the company have catalyzed the technological innovation of the offshore petroleum industry.

  4. FRIDAY: EPA Administrator Visiting Georgia Tech to Discuss Manufacturing Innovation and Environmental Sustainability

    Science.gov (United States)

    ATLANTA - On Friday, EPA Administrator Gina McCarthy will visit Georgia Tech to speak about the connection between manufacturing innovation and environmental sustainability. McCarthy will meet with more than 50 high school students and faculty parti

  5. Definition of a short-cut methodology for assessing earthquake-related Na-Tech risk.

    Science.gov (United States)

    Busini, Valentina; Marzo, Enrico; Callioni, Andrea; Rota, Renato

    2011-08-15

    Na-Tech (Natural and Technological) refers to industrial accidents triggered by natural events such as storms, earthquakes, flooding, and lightning. Herein, a qualitative methodology for the initial assessment of earthquake Na-Tech risk has been developed as a screening tool to identify which situations require a much more expensive Quantitative Risk Analysis (QRA). The proposed methodology, through suitable Key Hazard Indicators (KHIs), identifies the Na-Tech risk level associated with a given situation (i.e., a process plant located in a given territory), using the Analytical Hierarchy Process as a multi-criteria decision tool for the evaluation of such KHIs. The developed methodology was validated by comparing its computational results with QRA results that involved Na-Tech events previously presented in literature.

  6. Kalam's visit to cement Indo-Swiss ties in high tech area

    CERN Multimedia

    Sumir, Paul

    2005-01-01

    Seeking to boost Indo-Swiss cooperation in high tech areas, President APJ Abdul Kalam arrived in Geneva on a four-day visit to Switzerland aimed at firming up plans for future cooperation with the CERN

  7. Virginia Tech mourns the loss of Dr. Bernard "Bernie" F. Feldman

    OpenAIRE

    Owczarski, Mark

    2004-01-01

    Bernard "Bernie" F. Feldman of Check, Va., professor of biomedical sciences and pathobiology in the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech , was killed in an automobile accident Feb. 19.

  8. The Trail Inventory of Bayou Teche National Wildlife Refuge [Cycle 1

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to create a baseline inventory of all non-motorized trails on Bayou Teche National Wildlife Refuge. Trails in this inventory are...

  9. Violence-prevention summit at Virginia Tech tackles bullying, gender-based violence, more

    OpenAIRE

    2010-01-01

    Bullying in schools, aggression in the workplace, violence against women -- all are complex problems. On Nov. 12 and 13, Virginia Tech hosts a gathering to make recommendations about violence prevention.

  10. High-Tech Blood Sugar Monitors May Help People with Type 1 Diabetes

    Science.gov (United States)

    ... gov/news/fullstory_163211.html High-Tech Blood Sugar Monitors May Help People With Type 1 Diabetes ... need insulin shots every day manage their blood sugar levels safely, two new studies suggest. Also known ...

  11. Technology for Tomorrow---High-Tech Exhibition Held in HONG KONG

    Institute of Scientific and Technical Information of China (English)

    Fang Lin

    1997-01-01

    @@ "Technology for Tomorrow"--- High-Tech Exhibition has been held by Hong Kong Science & Technology Sector for Celebration of Return of Sovereignty Association and China Association Science & Technology on June 28 to July 4, 1997 in Hong Kong.

  12. Virginia Tech's Ashley White named to USA Today All-USA First Team

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    Virginia Tech senior Ashley White, a University Honors student pursuing degrees in both materials science and engineering and music performance, has been named to USA Today's All-USA College Academic First Team.

  13. Virginia Tech team qualifies as DARPA Urban Challenge semi-finalist

    OpenAIRE

    Crumbley, Liz

    2007-01-01

    "VictorTango," a team of Virginia Tech engineering and geography students, will travel to Victorville, Calif., for the national qualifying rounds of the Urban Challenge autonomous vehicle competition, sponsored by the Defense Advanced Research Projects Agency (DARPA).

  14. FDA OKs High-Tech Diabetes Device to Help Replace Fingerstick Tests

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_162638.html FDA OKs High-Tech Diabetes Device to Help Replace ... too low, and potentially incorrect insulin dosing, the FDA said. The Dexcom G5 is the first continuous ...

  15. Comparative Analysis of Capital Productivity in China's High-Tech Industries

    Institute of Scientific and Technical Information of China (English)

    LingWang; AdamSzirmai

    2005-01-01

    While labor productivity is a topic of constant debate and has been studied extensively, far less attention has been devoted to the question of capital productivity. Productive use of physical capital is an important source of economic growth and investment return. This paper presents a comparative study of capital productivity in China's high-tech industry. Using a version of the perpetual inventory method (PIM), new estimates have been made of the physical capital stock by sector. Capital productivity in China's high-tech industry is higher than in total manufacturing, but the gap between them has been shrinking. Comparison with high-tech industries in the US., highlights that China's high-tech industries could play a more important role in the growth of manufacturing and the whole economy.

  16. Maya Angelou to speak during Virginia Tech's third annual Martin Luther King Jr. celebration

    OpenAIRE

    Williams, Meghan

    2008-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  17. Maya Angelou to visit Virginia Tech during third annual Martin Luther King, Jr. celebration

    OpenAIRE

    Williams, Meghan

    2007-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  18. Biomedical Engineering Bionanosystems Research at Louisiana Tech University

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, James; Lvov, Yuri; Hegab, Hisham; Snow, Dale; Wilson, Chester; McDonald, John; Walker, Lynn; Pratt, Jon; Davis, Despina; Agarwal, Mangilal; DeCoster, Mark; Feng, June; Que, Long; O' Neal, Chad; Guilbeau, Eric; Zivanovic, Sandra; Dobbins, Tabbetha; Gold, Scott; Mainardi, Daniela; Gowda, Shathabish; Napper, Stan

    2010-03-25

    The nature of this project is to equip and support research in nanoengineered systems for biomedical, bioenvironmental, and bioenergy applications. Funds provided by the Department of Energy (DoE) under this Congressional Directive were used to support two ongoing research projects at Louisiana Tech University in biomedical, bioenvironmental, and bioenergy applications. Two major projects (Enzyme Immobilization for Large Scale Reactors to Reduce Cellulosic Ethanol Costs, and Nanocatalysts for Coal and Biomass Conversion to Diesel Fuel) and to fund three to five additional seed projects were funded using the project budget. The project funds also allowed the purchase and repair of sophisticated research equipment that will support continued research in these areas for many years to come. Project funds also supported faculty, graduate students, and undergraduate students, contributing to the development of a technically sophisticated work force in the region and the State. Descriptions of the technical accomplishments for each funded project are provided. Biofuels are an important part of the solution for sustainable transportation fuel and energy production for the future. Unfortunately, the country's appetite for fuel cannot be satisfied with traditional sugar crops such as sugar cane or corn. Emerging technologies are allowing cellulosic biomass (wood, grass, stalks, etc.) to also be converted into ethanol. Cellulosic ethanol does not compete with food production and it has the potential to decrease greenhouse gas (GHG) emissions by 86% versus current fossil fuels (current techniques for corn ethanol only reduce greenhouse gases by 19%). Because of these advantages, the federal government has made cellulosic ethanol a high priority. The Energy Independence and Security Act of 2007 (EISA) requires a minimum production of at least 16 billion gallons of cellulosic ethanol by 2022. Indeed, the Obama administration has signaled an ambitious commitment of achieving

  19. U.S. Army flyover hosted by the Virginia Tech Corps of Cadets Friday and Saturday

    OpenAIRE

    2008-01-01

    The Virginia Tech Corps of Cadets and the Army ROTC Department will sponsor, barring weather or operational factors, a military aircraft flyover with two AH-64 Apache attack helicopters from the Combat Aviation Brigade of the 82nd Airborne Division from Fort Bragg, N.C., during pre-game ceremonies of the Virginia Tech vs. Western Kentucky University football game to be held Saturday, Oct. 4.

  20. Definition of a shortcut methodology for assessing flood-related Na-Tech risk

    OpenAIRE

    Marzo, E.; Busini, V.; Rota, R.

    2012-01-01

    In this paper a qualitative methodology for the initial assessment of flood-related Na-Tech risk was developed as a screening tool to identify which situations require a much more expensive quantitative risk analysis (QRA). Through the definition of some suitable key hazard indicators (KHIs), the proposed methodology allows the identification of the Na-Tech risk level associated with a given situation; the analytical hierarchy process (AHP) was used as a multi-criteria decis...

  1. Sieciowe usługi informacyjne dla nauk technicznych : BazTech, BazTOL

    OpenAIRE

    2007-01-01

    The paper presents the current state and plans for development of the BazTech "Polish Technical Journals Contents" database. It is created by 22 academic libraries and centers for scientific information. The project is coordinated by the Cracow University of Technology. The Baz Tech database, situated at http://baztech.icm.edu.pl (ICM UW server), within the framework of the project "Virtual Scientific Library" lists over 400 journals. The paper also describes the assumptions for the creation ...

  2. Problems and Countermeasures of Zhejiang High-Tech Enterprises Industry-University-Institute Cooperation in China

    Science.gov (United States)

    Zhou, Qing; Mao, Chong-Feng; Hou, Lin

    Industry-university-institute cooperation is an important means to accelerate technical development and achievements for high-tech enterprises. Considering that Zhejiang high-tech enterprises existed some problems which included low cooperative level, single distribution, weak secondary R&D ability, obvious risk and so on, government should play an guiding role on improving information service system, enhancing cooperative level, promoting scientific intermediary service organization system construction, and building better environment for Industry-university-institute cooperation.

  3. HI-TECH BUSINESS IN ECONOMICALLY DEVELOPED COUNTRIES AND ITS INTEGRATION MECHANISM

    Directory of Open Access Journals (Sweden)

    V. N. Voronina

    2011-01-01

    Full Text Available In the hi-tech sphere, business integration forms widely wary. Particularly interesting is a way of such integration practiced in Japan through associations called «keiretsu» whose functioning mechanism is considered in detail. Specific features of this approach make it advantageous incomparison to classic western firm integration ways. Still, experiences gained in USA and some European countries, particularly in Finland, are of interest for Russian hi-tech business too.

  4. K2 Warm Jupiters with the LCOGT TECH collaboration

    Science.gov (United States)

    Shporer, Avi; Bayliss, Daniel; Cochran, William D.; Colón, Knicole D.; Dragomir, Diana; Palle, Enric; Potter, Stephen; Siverd, Robert; LCOGT TECH Collaboration

    2016-06-01

    Many transiting gas giant planets on short orbital periods (so called hot Jupiters) have larger radii than theoretically expected. Although several explanations have been proposed, none have completely solved this puzzle. As the number of known transiting planets grew a correlation was identified between gas giant radius and the stellar incident flux. Still, it is not clear whether this correlation is causation. Several questions remain and answering them will characterize in more detail this observed correlation and in turn the process responsible for the inflated radii, such as: Is the lack of inflated warm Jupiters a robust feature? What is the incident flux below which there are no inflated gas giants? How low in incident flux does this correlation stretch? These questions arise since there are only a small number of transiting gas giants with low incident flux, below about 108 erg/s/cm2, corresponding to orbital periods of about 10 days and longer for a Sun-like host star. Discovering and confirming more transiting warm Jupiters is the goal of this project, undertaken by the LCOGT Transiting Exoplanet CHaracterization (TECH) team. We are using K2 as our main source of transiting warm Jupiter candidates, with a few candidates discovered in each K2 campaign. LCOGT telescopes are being used for obtaining additional ground-based transit light curves, which are critical for confirming and refining the K2 transit ephemeris as outliers during ingress or egress of the few transit events observed by K2 can bias the measured ephemeris. Further ground-based follow-up data, including spectroscopy, radial velocities, and high angular resolution imaging, are obtained by facilities directly accessible by LCOGT TECH team members. In addition, once LCOGT’s Network of Robotic Echelle Spectrographs (NRES) are deployed in the near future they will allow obtaining spectroscopy and radial velocities with LCOGT facilities. On top of studying the inflated hot Jupiter conundrum

  5. Fine-needle aspiration cytology of mammary fibroadenoma: a comparison of ThinPrep® and cytospin preparations.

    Science.gov (United States)

    Ly, Thai Yen; Barnes, Penny J; Macintosh, Rebecca F

    2011-03-01

    Mammary fibroadenoma (FA) is a lesion frequently sampled and diagnosed by fine-needle aspiration (FNA). Accurate cytologic diagnosis of this common benign lesion is important as this can lead to non-surgical, conservative management when breast imaging and clinical examination are concordant. In most instances, a confident diagnosis of FA is possible because of a characteristic cytologic appearance that includes hypercellularity, large epithelial cell groups, staghorn epithelial configurations, stromal fragments, and numerous background stripped nuclei. Nevertheless, FAs can be diagnostically challenging because of shared cytomorphologic features with other benign lesions and low-grade carcinoma. As such, FA is a well-recognized source of false results on FNA cytology. Furthermore, there are reports that newer thin layer cytopreparatory techniques, including the ThinPrep® (TP) system (Hologic Corp., Bedford, MA), alter the appearance of FA on FNA compared to conventional preparations and may compromise accurate cytologic diagnosis. Copyright © 2010 Wiley-Liss, Inc.

  6. Guide for the preparation of proposals for the Pre-Freshman Engineering Program: PREP - 1984 (for minorities and women)

    Energy Technology Data Exchange (ETDEWEB)

    None

    1983-08-01

    The Pre-Freshman Engineering Program (PREP) for minorities and women (formerly PREFACE) will provide funds to colleges and universities for projects aimed at seeking out minority group individuals and women during junior high school and high school years (7th grade through 12th grade) and providing them with enrichment experiences. These experiences shall consist of activities to identify, motivate and prepare students for engineering studies. Emphasis is on the individuals identified, regardless of where they may decide to matriculate for undergraduate studies. Work experience is believed to contribute to the success of these projects because it exposes students to the real world of work of the professional engineer. However, no DOE funds may be used directly to support such work experiences. Eligible organizations, limitations of funding, preparation and submission of proposals, evaluation and selection of proposals, and the final report are discussed.

  7. State support of the high-tech exports: comparative analysis and lessons for Ukraine

    Directory of Open Access Journals (Sweden)

    Yevgen Panchenko

    2016-12-01

    Full Text Available The nature of the natural increase in the share of high-tech exports in the overall world exports and trade in general is revealed. The trends in geographical and industrial developments of a high-tech exports in 2004-2015 are shown in the world, developed countries and the EU. Based on the study of dynamics of the high-tech exports of the leading countries in general, as well as engineering products segment, the basic models of state regulation in this sphere are identified i.e. active dirigisme, moderate dirigisme and liberalism. The experience of maintaining a high-tech exports to the US, Germany, Britain, Japan, South Korea and China is summarized. The tendencies of high-tech exports of Ukrainian enterprises in industries such as aerospace engineering, electronics and telecommunications, scientific instruments, computer and office appliances, as well as military industrial products were analyzed. The directions of forming the state support of domestic exporters of high-tech products were identified.

  8. Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia.

    Directory of Open Access Journals (Sweden)

    Sebastiaan M Bol

    Full Text Available BACKGROUND: Infection with HIV-1 may result in severe cognitive and motor impairment, referred to as HIV-1-associated dementia (HAD. While its prevalence has dropped significantly in the era of combination antiretroviral therapy, milder neurocognitive disorders persist with a high prevalence. To identify additional therapeutic targets for treating HIV-associated neurocognitive disorders, several candidate gene polymorphisms have been evaluated, but few have been replicated across multiple studies. METHODS: We here tested 7 candidate gene polymorphisms for association with HAD in a case-control study consisting of 86 HAD cases and 246 non-HAD AIDS patients as controls. Since infected monocytes and macrophages are thought to play an important role in the infection of the brain, 5 recently identified single nucleotide polymorphisms (SNPs affecting HIV-1 replication in macrophages in vitro were also tested. RESULTS: The CCR5 wt/Δ32 genotype was only associated with HAD in individuals who developed AIDS prior to 1991, in agreement with the observed fading effect of this genotype on viral load set point. A significant difference in genotype distribution among all cases and controls irrespective of year of AIDS diagnosis was found only for a SNP in candidate gene PREP1 (p = 1.2 × 10(-5. Prep1 has recently been identified as a transcription factor preferentially binding the -2,518 G allele in the promoter of the gene encoding MCP-1, a protein with a well established role in the etiology of HAD. CONCLUSION: These results support previous findings suggesting an important role for MCP-1 in the onset of HIV-1-associated neurocognitive disorders.

  9. PrismTech Data Distribution Service Java API Evaluation

    Science.gov (United States)

    Riggs, Cortney

    2008-01-01

    My internship duties with Launch Control Systems required me to start performance testing of an Object Management Group's (OMG) Data Distribution Service (DDS) specification implementation by PrismTech Limited through the Java programming language application programming interface (API). DDS is a networking middleware for Real-Time Data Distribution. The performance testing involves latency, redundant publishers, extended duration, redundant failover, and read performance. Time constraints allowed only for a data throughput test. I have designed the testing applications to perform all performance tests when time is allowed. Performance evaluation data such as megabits per second and central processing unit (CPU) time consumption were not easily attainable through the Java programming language; they required new methods and classes created in the test applications. Evaluation of this product showed the rate that data can be sent across the network. Performance rates are better on Linux platforms than AIX and Sun platforms. Compared to previous C++ programming language API, the performance evaluation also shows the language differences for the implementation. The Java API of the DDS has a lower throughput performance than the C++ API.

  10. The New Mexico Tech Extrasolar Spectroscopic Survey Instrument (NESSI)

    Science.gov (United States)

    Creech-Eakman, Michelle J.; Jurgenson, C.; Vasisht, G.; Swain, M.; Boston, P.; Santoro, F.

    2010-01-01

    We present the design and scientific objectives behind NESSI, a near-infrared spectroscopic purpose-built for studying exoplanet atmospheres. This instrument is being designed and assembled by a team of scientists and engineers at New Mexico Tech (NMT), the Magdalena Ridge Observatory (MRO) and NASA's Jet Propulsion Lab (JPL), and is scheduled for deployment in late 2010 at the MRO 2.4m telescope. NESSI's unique design is driven by recent space and ground-based NIR spectroscopy of exoplanet atmospheres by members of our team. Optimization of the instrument to achieve 0.01% relative accuracies in spectra of exoplanetary molecular constituents requires careful attention to certain design features and a new technical approach. We present an overview of NESSI's design, including the four major subassemblies: 1) a field derotator, 2) a reimaging module, 3) an optical guiding module, and 4) a multi-object spectrograph subassembly. We also present an overview of our science program specifically designed to build the community of exoplanet researchers and students in NM. The financial support of our team and NESSI itself have been made possible by a NM NASA EPSCoR grant, matching funds from the NMT administration, and internal support for the NESSI hardware from Dr. Van Romero, NMT's Research Vice-President.

  11. "Sci-Tech - Couldn't be without it !"

    Science.gov (United States)

    2002-03-01

    Launch of a Major European Outreach Programme Seven of Europe's leading Research Organizations [1] launch joint outreach programme for the European Science and Technology Week at the Technopolis Museum in Brussels on 22 March. Their aim is to show Europeans how today's society couldn't be without fundamental research . Could you imagine life without mobile phones, cars, CD players, TV, refrigerators, computers, the internet and the World Wide Web, antibiotics, vitamins, anaesthetics, vaccination, heating, pampers, nylon stockings, glue, bar codes, metal detectors, contact lenses, modems, laser printers, digital cameras, gameboys, play stations...? Technology is everywhere and used by everyone in today's society, but how many Europeans suspect that without studies on the structure of the atom, lasers would not exist, and neither would CD players? Most do not realise that most things they couldn't be without have required years of fundamental research . To fill this knowledge gap, the leading Research Organizations in Europe [1], with the support of the research directorate of the European Commission, have joined forces to inform Europeans how technology couldn't be without science, and how science can no longer progress without technology. The project is called...... Sci-Tech - Couldn't be without it! Sci-Tech - Couldn't be without it! invites Europeans to vote online in a survey to identify the top ten technologies they can't live without. It will show them through a dynamic and entertaining Web space where these top technologies really come from, and it will reveal their intimate links with research. Teaching kits will be developed to explain to students how their favourite gadgets actually work, and how a career in science can contribute to inventions that future generations couldn't be without. The results of the survey will be presented as a series of quiz shows live on the Internet during the Science Week, from 4 to 10 November. Sci-tech - Couldn't be without

  12. Life Sciences at the University of Yachay Tech in Ecuador

    Directory of Open Access Journals (Sweden)

    Graciela Salum

    2016-09-01

    Full Text Available Yachay Tech University, home for more than 900 students and growing, has entered a new era and made a step forward in its development and fulfillment of the hopes placed on it. Indeed, its Schools have launched their careers offering the students a wide range of choices among programs of high academic level. The School of Biological Sciences and Engineering has started its two careers. The first one, coined "Biology," is designed for students aiming to gain knowledge either in "Organisms, Ecology and Evolution" or "Molecular and Cellular Biology." The second path, referred to as "Biomedical Engineering", is the first program of its type in Ecuador and is intended for students wishing to apply the principles and problem-solving techniques of Engineering to Biology and Medicine. These students will be able to acquire knowledge at the interface between Biology and Medicine, on one side, and Natural Sciences, such as Physics and Chemistry, and Engineering sciences, such as Flow Dynamics, Informatics and Electronics, on the other side.

  13. Talking about the Influence of the Quality of Sci-tech Novelty Retrieval Personnel on the Quality of Sci-tech Novelty Retrieval%浅谈科技查新人员素质对查新质量的影响

    Institute of Scientific and Technical Information of China (English)

    刘燕

    2015-01-01

    分析了大数据背景下高校图书馆科技查新的发展现状,阐述了查新员综合素质(包括信息意识、专业素养、情报分析能力和职业道德修养)对查新质量的影响,提出应通过参与学术会议与信息数据资源建设,培养查新团队意识及职业道德,提高科技查新人员的综合素养。%This paper analyzes the development status of sci-tech novelty retrieval in university library under the background of big data, expounds the influence of the quality of novelty retrieval personnel including information awareness, professional quality, intelligence analysis ability and professional moral accomplishment on the quality of sci-tech novelty retrieval, and points out that should cultivate the team awareness and professional ethics of novelty retrieval and improve the comprehensive quality of sci-tech novelty retrieval personnel through participating in academic conferences and information resource construction.

  14. PREFACE: 2nd Russia-Japan-USA Symposium on the Fundamental and Applied Problems of Terahertz Devices and Technologies (RJUS TeraTech - 2013)

    Science.gov (United States)

    Karasik, Valeriy; Ryzhii, Viktor; Yurchenko, Stanislav

    2014-03-01

    The 2nd Russia-Japan-USA Symposium 'The Fundamental & Applied Problems of Terahertz Devices & Technologies' (RJUS TeraTech - 2013) Bauman Moscow State Technical University Moscow, Russia, 3-6 June, 2013 The 2nd Russia-Japan-USA Symposium 'The Fundamental & Applied Problems of Terahertz Devices & Technologies' (RJUS TeraTech - 2013) was held in Bauman Moscow State Technical University on 3-6 June 2013 and was devoted to modern problems of terahertz optical technologies. RJUS TeraTech 2013 was organized by Bauman Moscow State Technical University in cooperation with Tohoku University (Sendai, Japan) and University of Buffalo (The State University of New York, USA). The Symposium was supported by Bauman Moscow State Technical University (Moscow, Russia) and Russian Foundation for Basic Research (grant number 13-08-06100-g). RJUS TeraTech - 2013 became a foundation for sharing and discussing modern and promising achievements in fundamental and applied problems of terahertz optical technologies, devices based on grapheme and grapheme strictures, condensed matter of different nature. Among participants of RJUS TeraTech - 2013, there were more than 100 researchers and students from different countries. This volume contains proceedings of the 2nd Russia-Japan-USA Symposium 'The Fundamental & Applied Problems of Terahertz Devices & Technologies'. Valeriy Karasik, Viktor Ryzhii and Stanislav Yurchenko Bauman Moscow State Technical University Symposium chair Anatoliy A Aleksandrov, Rector of BMSTU Symposium co-chair Valeriy E Karasik, Head of the Research and Educational Center 'PHOTONICS AND INFRARED TECHNOLOGY' (Russia) Invited Speakers Taiichi Otsuji, Research Institute of Electrical Communication, Tohoku University, Sendai, Japan Akira Satou, Research Institute of Electrical Communication, Tohoku University, Sendai, Japan Michael Shur, Electrical, Computer and System Engineering and Physics, Applied Physics, and Astronomy, Rensselaer Polytechnic Institute, NY, USA Natasha

  15. Projekt wprowadzania danych o pracach doktorskich i magisterskich do "Bazy danych o zawartosci polskich czasopism technicznych" BazTech http://baztech.icm.edu.pl : koncepcja ogólna

    OpenAIRE

    2005-01-01

    The project aims to improve the "Polish Technical Journal Contents" BazTech which now is a database containing bibliographic details and abstracts from the Polish technical journals on engineering, technology, sciences and the environment. The main aim of the project is to widen the existing document types to theses and dissertations. The proposed concept assumes organizational methods and technical solutions. The project is based on analysis theses and dissertations in participating insti...

  16. Effect of Thin Prep® imaging system on laboratory rate and relative sensitivity of atypical squamous cells, high-grade squamous intraepithelial lesion not excluded and high-grade squamous intraepithelial lesion interpretations

    OpenAIRE

    Brooke R Koltz; Russell, Donna K; Naiji Lu; Bonfiglio, Thomas A.; Sharlin Varghese

    2013-01-01

    Introduction: Automated screening of Thin Prep ® Papanicolaou Tests has become increasingly common in clinical practice. Increased productivity has initiated laboratory use of the Thin Prep ® Imaging System (TIS). Increased sensitivity is a potential additional benefit of TIS. Published studies have shown an increase in discovery of dysplastic cells. This study evaluates the effect of TIS on the incidence of atypical squamous cells high-grade squamous intraepithelial lesion not excluded (ASC-...

  17. Performance evaluation of the new Roche cobas AmpliPrep/cobas TaqMan HCV test, version 2.0, for detection and quantification of hepatitis C virus RNA

    NARCIS (Netherlands)

    S.D. Pas (Suzan); R. Molenkamp (Richard); J. Schinkel (Janke); S. Rebers; C. Copra (Cederick); S. Seven-Deniz; D. Thamke (Diana); R.J. de Knegt (Robert); B.L. Haagmans (Bart); M. Schutten (Martin)

    2013-01-01

    textabstractTo evaluate the analytical performance and explore the clinical applicability of the new Roche cobas AmpliPrep/cobas TaqMan HCV test, v2.0 (CAP/CTM v2.0), a platform comparison was performed on panels and diagnostic samples with the Roche cobas AmpliPrep/cobas TaqMan HCV test (CAP/CTM v1

  18. Apparent Level of Sci-tech Achievements and Sci-tech Evaluation%科技成果的表观水平与科技评价

    Institute of Scientific and Technical Information of China (English)

    禹慧明

    2012-01-01

    This paper gives the concept of " apparent level of sci - tech achievements ". It discusses the reasons that the apparent level is popular in the sci -tech evaluation, the drawbacks that the apparent level is used for sci - tech evaluation , and the countermeasures to improve the quality of sci - tech achievements . The paper also points out that sci - lech evaluation will identify the gaps which has a "potential energy " i. e. "energy of position". The sci - tech rewards is the external conditions of transforming " potential energy " into the " kinetic energy ". Corrects evaluation can lead to correct identification, proper to reward and correct guidance. The reform should be necessary to take sci - lech evaluation and incentives as the main line , the various system innovation should be around the main line.%提出了“科技成果表观水平”的概念.论述了表观水平流行于科技成果评价的原因,运用表观水平进行科技评价存在的弊端以及提高科技成果质量的对策.指出科技评价可以发现差距,有差距就会产生“势能”,科技奖励是将“势能”转化成“动能”和动力的外在条件;只有正确评价才能正确鉴别,才能奖罚得当,才能正确引导;制度改革应以科技评价和激励政策为主线,从上到下的各种制度都应围绕这条主线进行创新.

  19. 78 FR 52430 - Withdrawal of Approval of New Animal Drug Applications; Quali-Tech Products, Inc.; Bambermycins...

    Science.gov (United States)

    2013-08-23

    ... Animal Drug Applications; Quali- Tech Products, Inc.; Bambermycins; Pyrantel; Tylosin; Virginiamycin... (pyrantel tartrate), NADA 132-705 for FLAVOMYCIN (bambermycins), and NADA 133-335 for STAFAC...

  20. Empirical Study on the Measurement of the Technical Efficiency of Jilin Province’s Five High-tech Industries

    Directory of Open Access Journals (Sweden)

    Yao Jie

    2017-01-01

    Full Text Available This paper first analyzed the industrial distribution of Jilin province’s high-tech enterprises, and then selected 13 input and output indicators based on analyzing the influence factors of high-tech industry. Through the correlation analysis between each indicator’s relevant data, the paper constructed the technical efficiency evaluation model of Jilin Province’s high-tech industries including 12 indicators. After that it measured the technical efficiency of Jilin Province’s five high-tech industries from 2004 to 2013 by using DEA analysis method. Finally, this paper drew conclusions and gave suggestions.

  1. Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

    DEFF Research Database (Denmark)

    Rebolj, Matejka; Rask, Johanne; van Ballegooijen, Marjolein;

    2015-01-01

    BACKGROUND: We compared the sensitivity and specificity of liquid-based cytology (LBC) and computer-assisted reading for SurePath/FocalPoint and ThinPrep with those of manually read conventional cytology in routine cervical screening in four Danish laboratories. METHODS: Using data from five...... nationwide registers, technological phases were identified by slide preparation, reading technique, and triage of borderline cytology. Trends in the detection of cervical intraepithelial neoplasia (CIN) were an indicator of the technology's relative sensitivity, and trends in false-positive tests...... an indicator of relative specificity. RESULTS: At 23-29 years, SurePath/FocalPoint statistically significantly increased the detection of ⩾CIN3 by 85% compared with manually read conventional cytology. The 11% increase with ThinPrep was not significant. At 30-44 years, the increase with Sure...

  2. A case study of chewed Truvada(®) for PrEP maintaining protective drug levels as measured by a novel urine tenofovir assay.

    Science.gov (United States)

    Lalley-Chareczko, Linden; Clark, Devon; Zuppa, Athena F; Moorthy, Ganesh; Conyngham, Caitlin; Mounzer, Karam; Koenig, Helen

    2017-03-06

    FTC/TDF (Truvada®) given as pre-exposure prophylaxis (PrEP) successfully blocks HIV when taken once daily prior to potential HIV exposure. A 22 year old male reported difficulty swallowing FTC/TDF for PrEP and subsequently began chewing the FTC/TDF tablets. Monthly urine samples assessed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) indicated tenofovir levels >1000 ng/mL, indicative of protection from HIV acquisition, over a 48 week period. Data from observational studies of HIV positive patients details the successful treatment of HIV using crushed FTC/TDF delivered via feeding and gastronomy tubes while small, randomized trials of healthy volunteers demonstrate bioequivalence between whole and crushed FTC/TDF.

  3. Nutritional recommendations of feedlot consulting nutritionists: The 2015 New Mexico State and Texas Tech University survey.

    Science.gov (United States)

    Samuelson, K L; Hubbert, M E; Galyean, M L; Löest, C A

    2016-06-01

    The 2015 feedlot consulting nutritionist survey is a collaborative project between New Mexico State University and Texas Tech University that focuses on summarizing the professional practices of consulting feedlot nutritionists and updates a 2007 survey. Forty-nine consulting feedlot nutritionists were asked to participate, of which 24 completed the survey. The nutritionists surveyed service over 14,000,000 cattle annually and were representatives from individual consulting practices (54.2%), corporate cattle feeding companies (20.8%), corporate feed manufacturing companies (20.8%), or a combination of consulting practices (4.2%). The survey was completed using a web-based survey tool and contained 101 questions that were divided into sections regarding general information about the consulting practice; general cattle management; receiving cattle management, diet adaption; mixers, feed mills, and feeding management; grains and grain processing; grain by-product use; roughage use; information about supplements and microingredients; liquid feed use; nutrient formulation; feed additive use; and information used as a basis for nutritional recommendations. In most cases, the results of the current survey were similar to those reported for the 2007 survey, with a few notable exceptions such as shifts in cattle numbers and preferences for specific feedstuffs. The present study introduced a number of new questions not included in the 2007 survey that focused on management strategies used in the receiving period. Data from this survey provide insight into current nutritional and management practices of consulting nutritionists and, as in past surveys, should be useful for informing national committees that make nutritional recommendations for cattle, as well as nutrition and management strategies employed within university research settings.

  4. 7th FTRA International Conference on Future Information Technology (FutureTech 2012)

    CERN Document Server

    Leung, Victor; Wang, Cho-Li; Shon, Taeshik; Advances in Complex Data Modeling and Computational Methods in Statistics

    2012-01-01

    This book is about Future Information Technology, Application, and Service (FutureTech 2012 volume 2). The topics of FutureTech 2012 cover the current hot topics satisfying the world-wide ever-changing needs. The FutureTech 2012 is intended to foster the dissemination of state-of-the-art research in all future IT areas, including their models, services, and novel applications associated with their utilization. The FutureTech 2012 will provide an opportunity for academic and industry professionals to discuss the latest issues and progress in this area. In addition, the conference will publish high quality papers which are closely related to the various theories, modeling, and practical applications in many types of future technology. The main scope of FutureTech 2012 is as follows. Hybrid Information Technology Cloud and Cluster Computing Ubiquitous Networks and Wireless Communications Multimedia Convergence Intelligent and Pervasive Applications Security and Trust Computing IT Management and Service Bioinfo...

  5. A new model on the use of ubiquitous technology (U-Tech as a learning tool

    Directory of Open Access Journals (Sweden)

    Muliati Sedek

    2014-08-01

    Full Text Available Laptops, smartphones and tablets which also known as ubiquitous technology or u-tech have been widely used by students in the university. However, study on the factors influencing it usage as not many comprehensive studies have been done related to it. A review of related literature reveals that factors, namely the Technology Competency (TC, Performance Expectancy (PE, Effort Expectancy (EE, Behavioural Intention (BI, Facilitating Conditions (FC and Social Status (SS influence its usage. Thus, the focus of this study was to confirm whether the determined factors contribute towards u-tech usage among students in the institutions of higher learning, particularly in Malaysia. This study was based on a quantitative research in which the Structural Equation Modelling using AMOS was employed. The results attained from the analysis produced a reliable model towards u-tech usage. Therefore, it can be concluded that, u-tech usage described by the five factors. This study has suggested that the university administration should play an active role in disseminating any news that is related to the usefulness of u-tech.

  6. Evaluation of a new preparative supercritical fluid chromatography system for compound library purification: the TharSFC SFC-MS Prep-100 system.

    Science.gov (United States)

    Ebinger, Katalin; Weller, Harold N; Kiplinger, Jeffrey; Lefebvre, Paul

    2011-06-01

    Preparative HPLC-MS is often the method of choice for purification of small amounts (<100mg) of diverse new molecules, such as compound libraries for drug discovery. The method is robust, well proven, and widely applicable. In contrast, preparative supercritical fluid chromatography coupled with mass spectrometry (SFC-MS) has seen only slow acceptance for the same application--despite some potential scientific and economic advantages. One of the reasons for slow adoption of SFC-MS is the lack of well-proven, robust, and commercially available instrumentation. In early 2009, TharSFC (a Waters Company, Pittsburgh, PA) introduced a new fully integrated system for preparative SFC-MS: The SFC-MS Prep-100. We report herein an objective evaluation of the SFC-MS Prep-100, including tests for pump and autosampler performance, sample recovery, sample carryover, fraction triggering, detector/fraction collector synchronization, and overall robustness. Our results suggest that the SFC-MS Prep-100 represents a significant advance over previous generation instrumentation.

  7. Validation of Cobas AmpliPrep/Cobas TaqMan HIV-1 Test on dried blood spots

    Directory of Open Access Journals (Sweden)

    N Ruiz

    2012-11-01

    Full Text Available The plasma specimen is the gold standard for viral load monitoring, the key method to assess the effect of antiviral chemotherapy and to monitor progression of the disease toward AIDS. Nevertheless, several works endorse the use of dried blood spots (DBS on filter paper for the reliable quantification of the levels needed to take therapeutic decisions, detect of treatment failure and monitor the occurrence of drug resistance. The purpose of this study was to validate the use of Cobas AmpliPrep/Cobas TaqMan HIV-1 test version 2.0, with DBS. To evaluate the performance of the above mentioned kit, three stages were involved: 1- Standardization of DBS working conditions, 2- Stability studies at three temperature conditions and 3- Performance evaluation of the kit using this alternative specimen. Additionally, the viral load was quantified in parallel (plasma and DBS to 43 genetically characterized samples, with different levels of viral load. The Pearson correlation coefficient was calculated and the prediction of the value of RNA in plasma starting from the obtained value in DBS was made. Linear regression analysis was performed and coefficients of variation in precision assays were calculated. The best conditions pickups to the work with DBS were: 100 µL of blood (2 spots/50 µl, dried time between 16 and 18 hours at room temperature and, elution of the blood, 2 hours, between 2 and 8°C; in TRIS-EDTA buffer. The samples on DBS proved to be stable during the study periods. A strong correlation was attained between the measurements of viral load in plasma and DBS samples (r=0.96. The detection rate was 90.7 and the coefficient of variation between the values obtained in plasma-DBS sample pairs averaged 3.42%. The CAP/CTM HIV-1 test provided a linear response in DBS, from 330 copies/mL to 420 000 copies/mL. Overall, coefficients of variation in precision tests were below 10%. Cobas AmpliPrep/Cobas TaqMan HIV-1 test version 2.0 had a good

  8. Yield oil of Jatropha curcas seeds of trees irrigated and fertilized with OMM-Tech; Rendimento de oleo de sementes de pinhao manso submetido a irrigacao e adubacao com OMM-Tech

    Energy Technology Data Exchange (ETDEWEB)

    Evangelista, Adao W.P.; Alves Junior, Jose; Barbosa, Ricardo A.F.; Frazao, Joaquim J.; Araujo, Fausto J.M. [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Escola de Agronomia e Engenharia de Alimentos. Setor de Engenharia Rural], E-mail: awpego@bol.com.br

    2010-07-01

    The purpose of this study was to evaluate the effects of irrigation and application of Organo-Minerals-Marine + Biotech (OMM-Tech) in yield oil of Jatropha curcas seeds. The experiment was conducted in an experimental area located in Federal University of Lavras, Brazil. A randomized block experimental design with subdivided parcels and three replications was used. The parcels were submitted to different OMM-Tech fertilizer application methods: T1 = control (no OMM-Tech); T2 = soil application (120 kg ha{sup -1} of OMM-Tech in a powder form); T3 = leaf application (OMM-Tech in a liquid form with a 5% concentration); T4 = soil + leaf application (60 kg ha{sup -1} of OMM-Tech in powder form + OMM-Tech in liquid form with a 2.5% concentration). The sub-plots received two different water management treatments: irrigated and no irrigated. A drip irrigation system with drippers spaced by 0.50 m was used. We evaluated yield oil of seeds in first production year. Jatropha trees irrigated showed a higher seeds oil yield than no irrigated trees. However, fertilization with OMM-Tech no influenced seed oil yield. Seeds oil yield of Jatropha trees irrigated was 34%, and no irrigated 27%. (author)

  9. Varying Interpretations of Technology as a Problem in Markets for Customised High-Tech Products

    DEFF Research Database (Denmark)

    Vendelø, Morten Thanning; Constantiou, Ioanna

    2012-01-01

    Firms involved in contracting and implementation of customised high-tech products face a number of challenges in their relationships with customers because of the underlying variability of complex technologies. Existing research proposes the use of rational decision models and represents technology...... as an input to the firm's production function that generates a specific return on investment when used appropriately. As such, existing research does not account for the parties' varying interpretations of complex technology. If these interpretations are not revealed and resolved they may decrease customer......-tech product in the software industry is analysed. Based on the insights obtained, we discuss the potential use of inquiring dialogue as a means to reveal information about the different interpretations held by the parties involved in contracting and implementing a customised high-tech product....

  10. Collaborative Innovation Research on High-tech Industry in the Center Delta

    Directory of Open Access Journals (Sweden)

    Yan Jingdong

    2017-01-01

    Full Text Available As a strong point in the Middle Rises Strategy, the Center Delta is of great significance to high-tech industry development. While the collaborative innovation is an effective way to promote the coordinated development of regional economy. This article selected electronic and communication equipment manufacturing industry of 3 provinces in the Center Delta as samples, built evaluation index system of collaborative innovation of high-tech industry, and put the relevant data into the system coordination degree model, in order to get the synergy of industrial innovation system and innovation environment system of 3 provinces. The empirical results shown that the industrial innovation system and innovation environment system coordination degree of Hubei province was the highest, while Jiangxi province was the lowest. Based on the empirical result analysis of the above-mentioned systems, this article put forward suggestions to promote the development of the high-tech industry collaborative innovation in the Center Delta.

  11. Recruitment of Minority Adolescents and Young Adults into Randomised Clinical Trials: Testing the Design of the Technology Enhanced Community Health Nursing (TECH-N) Pelvic Inflammatory Disease Trial

    Science.gov (United States)

    Trent, Maria; Chung, Shang-en; Gaydos, Charlotte; Frick, Kevin D.; Anders, Jennifer; Huettner, Steven; Rothman, Richard; Butz, Arlene

    2016-01-01

    Purpose Pelvic inflammatory disease (PID) disproportionately affects adolescent and young adult (AYA) women and can negatively influence reproductive health trajectories. Few randomized controlled trials (RCTs) have focused on strategies to improve outpatient adherence or to reduce reproductive morbidity in this population. This paper describes the research methods and preliminary effectiveness of recruitment, retention, and intervention strategies employed in a novel RCT designed to test a technology-enhanced community-health nursing (TECH-N) intervention among urban AYA with PID. Methods AYA women aged 13–25 years were recruited during acute PID visits in outpatient clinics and emergency departments (ED) to participate in this IRB-approved trial. Participants completed an audio-computerized self-interview (ACASI), provided vaginal specimens, and were randomized to standard treatment or the intervention. Intervention participants received text-messaging support for 30 days and a community health nurse (CHN) interventionist performed a home visit with clinical assessment within 5 days after enrollment. All patients received a full course of medications and completed research visits at 14-days (adherence), 30 days and 90 days with by an outreach worker. STI testing performed at the 30-and 90-day visits. Exploratory analyses using descriptive statistics were conducted to examine recruitment, retention, and follow-up data to test the overall design of the intervention. Results In the first 48 months, 64% of 463 patients were eligible for the study and 81.2% of 293 eligible patients were recruited for the study (63.3%); 238 (81.2%) of eligible patients were enrolled. Most participants were African American (95.6%) with a mean age of 18.6 (2.3). Ninety-four percent of individuals assigned to the TECH-N intervention completed the nursing visits. All completed visits have been within the 5-day window and over 90% of patients in both arms have been retained over the 3

  12. Iowa High School High Tech: Promoting Careers in Technology for Students with Disabilities. Final Report and Implementation Manual.

    Science.gov (United States)

    McQuillen, Terry; Nietupski, John; Berg, Deana Duncan; Daugherty, Vicki; Bildstein, Stephanie

    This final report and implementation manual describes the activities and outcomes of Iowa's High School High Tech (HSHT) program, a joint effort of Grant Wood Area Education Agency and Goodwill Industries of Southeast Iowa to inspire students with disabilities to pursue high tech careers. The program provides opportunities for students to learn…

  13. 77 FR 5291 - Thermo Tech Technologies Inc., T.V.G. Technologies Ltd., and Visual Frontier, Inc.; Order of...

    Science.gov (United States)

    2012-02-02

    ... From the Federal Register Online via the Government Publishing Office ] SECURITIES AND EXCHANGE COMMISSION Thermo Tech Technologies Inc., T.V.G. Technologies Ltd., and Visual Frontier, Inc.; Order of... lack of current and accurate information concerning the securities of Thermo Tech Technologies...

  14. E-mail service provided by Virginia Tech's server (pop.vt.edu, imap.vt.edu) is offline

    OpenAIRE

    Hincker, Lawrence

    2007-01-01

    E-mail service provided by Virginia Tech's server (pop.vt.edu or imap.vt.edu) is offline. The server has experienced a failure for two of its three power supplies. The maintenance contractor expects to have the repair components at Virginia Tech by midday Monday, March 5, 2007.

  15. Engineering for problem solving in future: Eco-social market economy and eco-social tech

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The paper differentiates approaches in technology (end-of-pipe, cleaner production, industrial ecology, zero emission and eco-social tech) and compares them in respect to the problem solving capacity on the ecological as well as social dimension by showing the eco-impact reduction and job creation. Eco-social-tech represents the approach with highest problem solution as it is based on “eco-social market economy”, which will the replace free market economy. The deep background of these innovations is “ecosophy”, the wisdom of nature, which serves as guideline for eco-restructuring the world.

  16. Raising Generation Tech Preparing Your Children for a Media-Fueled World

    CERN Document Server

    Taylor, Jim

    2012-01-01

    Today's children are being raised as 'digital natives' in a world dominated by popular culture and technology. TV shows, computers, video games, social networking sites, advertisements, and cell phones too often have an unnecessarily strong-and negative? influence on children.  But pulling the plug just isn't an option in a world where being connected is essential for success. In Raising Generation Tech,  noted parenting and new-media expert Dr. Jim Taylor explores how popular culture and technology shape children's lives. The essential message from Raising Generation Tech is that excessive

  17. Knowledge spillover and high-tech industry cluster: A literature review

    Science.gov (United States)

    Qian, Shen

    2017-04-01

    Knowledge spillover is one of the incentive forces for companies using more expenditure on R&D to shape cluster. This paper summarizes and reviews academic research literature from three aspects, of which contain the connotation of knowledge spillover in high-tech industry cluster, conduction mode of knowledge spillover effect in high-tech industry and explain factors of knowledge spillover effect. This paper devotes by assembling anterior divergent tributaries of works to assist in illuminating on this prosperous research area, based on previous research, and finally it notes that future research needs to pay attention to several aspects.

  18. Co-alignment between Environment Risk, Capital Structure, Growth and High-tech Firm Performance

    Institute of Scientific and Technical Information of China (English)

    LI Yan-xi; BAO Shi-ze

    2007-01-01

    To examine whether there is a co-alignment relationship between environment risk, capital structure, growth and high-tech firm performance, the environment risk was measured from the viewpoint of environment change, the long-term debt ratio was adopted as the measure of the capital structure, and the total asset growth and sales growth were chosen to measure the growth of high-tech firms. Regression analysis shows that there is a significant relationship between environment risk, growth and performance of hightech firms measured by the return on equity and cash flow, respectively.

  19. Current Situations of Agricultural Sci-tech Innovation and Development Path in Nantong

    Institute of Scientific and Technical Information of China (English)

    YUAN Chun-xin; SUN Qing-shan; QIU Hai-rong; ZHU Hai-yan; TANG Ming-xia; XUE Chen-xia

    2012-01-01

    Nantong is a typical region of large population and little land.The conflict between resources and environment is growing.Thus,the improvement of independent innovation ability based on current situations,oriented towards the future and relying on scientific and technological force directly decides the effect of strong economic city construction.Through analysis on achievements of agricultural sci-tech innovation works,existing problems and demand for developing modern agriculture in Nantong,we present development ideas,target orientation and basic principles of agricultural sci-tech innovation works in Nantong,and put forward eight paths.

  20. Shaking Up Biotech/Pharma: Can Cues Be Taken from the Tech Industry?

    Science.gov (United States)

    Wang, C Katherine

    2017-06-01

    The biotech and pharma (biotech/pharma) industry is in dire need of finding ways to increase efficacy, efficiency, and affordability of its products. The information and technology industry ("tech") industry, which is an industry similarly founded on inventions and innovation, may provide some food for thought. This perspective will demonstrate the shift that biotech/pharma is already making and will propose that the industry has an opportunity to compel change by adopting some aspects of the tech industry with regards to models for technology/product development and leadership attributes.

  1. CNPC to Implement Eight Sci-tech Projects for Promoting Onshore Petroleum Industry

    Institute of Scientific and Technical Information of China (English)

    Zhou Yongkang

    1996-01-01

    @@ During the Ninth Five-year Plan (1996-2000),petroleum sci-tech progress should meet the requirements of national economic growth and establishment of socialist market economic system. That means we should focus on economic efficiency to accelerate the development of onshore oil industry, implement actively the strategies of science and technologies to spur oil production, take key problems in petroleum production and construction as the major targets of sci-tech research, and push ahead with transformation of techniques into productive forces.

  2. BIOTECON diagnostics foodproof Listeria monocytogenes Detection Kit, 5' nuclease in combination with the foodproof ShortPrep II Kit.

    Science.gov (United States)

    Junge, Benjamin; Grönewald, Cordt; Berghof-Jäger, Kornelia

    2012-01-01

    A method was developed for the detection of Listeria monocytogenes in food. The method is based on real-time PCR using hydrolysis probes (5' Nuclease). This advanced PCR method was designed to reduce the time necessary to achieve results from PCR reactions and to enable the user to monitor the amplification of the PCR product simultaneously, in real-time. After DNA isolation using the BIOTECON foodproof ShortPrep II Kit designed for the rapid preparation of L. monocytogenes DNA for direct use in PCR, the real-time detection of L. monocytogenes DNA is carried out using the foodproof Listeria monocytogenes Detection Kit. The kit provides primers and hydrolysis probes for sequence-specific detection, convenient premixed reagents, and controls for reliable interpretation of results. For the internal comparison study, three different foods (soft cheese, coalfish, and smoked ham) were analyzed, chosen from the 15 food groups recommended by the AOAC Research Institute for detection of L. monocytogenes. From each food, 20 samples were inoculated with a low level (1-10 CFU/25 g) and 20 samples with a high level (10-50 CFU/25 g) of L. monocytogenes. Additionally, five nonspiked samples were prepared from each food. Depending on the matrix, the food samples were examined with the test kits and compared with the cultural methods according to the U.S. Food and Drug Administration's Bacteriological Analytical Manual or the U.S. Department of Agriculture/Food Safety and Inspection Service Microbiology Laboratory Guidebook.

  3. Has the ThinPrep method of cervical screening maintained its improvement over conventional smears in terms of specimen adequacy?

    LENUS (Irish Health Repository)

    Treacy, A

    2009-04-01

    Liquid-based cytology (LBC) has replaced conventional smear assessment in many centers over recent years. In our laboratory this transfer took place in 1999. At that time we performed a split sample study comparing the conventional method of cervical smear evaluation with the ThinPrep system. This split sample study identified a dramatic improvement in specimen adequacy with LBC. While 11% of conventional preparations were reported as unsatisfactory and almost 9% were reported as suboptimal, evaluation of the same cases using LBC saw this combined figure reduced to 2.3%. AIM: To evaluate whether this dramatic fall in unsatisfactory smears has been maintained with the use of LBC. The database for all smears reported for 2005 (100% LBC) was interrogated. The number of unsatisfactory reports was calculated. The reason for an unsatisfactory report was recorded for each case. The overall unsatisfactory rate was compared with that reported in the 1999 split sample study. A total of 41,312 smear tests were reported in 2005. 1,342 (3.25%) were reported as unsatisfactory. Our findings support the ongoing value of LBC in a routine cervical screening laboratory in terms of continuing to maintain a low rate of unsatisfactory smears.

  4. Preliminary study of a new, fully automated system for liquid-based cytology: the NovaPrep® processor system.

    Science.gov (United States)

    Esquivias López-Cuervo, Javier; Montalbán Beltran, Estanislao; Cuadros Lopez, Jose Luis; Alonso Castillo, Angeles; Nieto Sanchez, Teresa

    2011-01-01

    To evaluate a fully automated system for liquid-based cytology (LBC): the NovaPrep® Processor System (NPS), which is based on the new concept of double decantation, versus conventional cytology (CC), the gold standard for cytology. We performed a preliminary comparative study involving 1,129 female patients who underwent sampling for a Pap test; the sample was first smeared for CC and then, using the remaining specimen on the brush, for LBC with the NPS. The performances of CC and NPS were evaluated for accuracy and compared using the gold standard of a combination of one of the two methods of pathological cytology with screening for positive human papilloma virus, quantification of cells (normal and pathological), and improvement in the quality of samples and reading time. The results showed improvement in sensitivity (3.81% for CC vs. 4.52% for NPS) with a specificity superior to 90% for both, a markedly decreased number of unsatisfactory specimens, notably samples containing too many inflamed cells (7.4% for CC vs. 0.5% for NPS), and a shortening of the reading time, which was three times less using NPS. This preliminary study showed a gain in sensitivity, a drop in the number of unsatisfactory specimens and a reduction in reading time with NPS. The results achieved using this fully automated LBC procedure are very promising and will hopefully reduce the overall cost of cervical cancer screening in the future. Copyright © 2011 S. Karger AG, Basel.

  5. Participants needed for new study on parental involvement in treatment of children with phobias

    OpenAIRE

    Doss, Catherine

    2007-01-01

    Virginia Tech's Child Study Center, part of the College of Science, is seeking children with phobias, and their parents, to participate in a study of the effectiveness of parental involvement in treating their children's fears. In order to be considered for the project, children must be between the ages of 7 and 12, have a specific phobia, and be able to travel to Blacksburg for the treatment program.

  6. NASA Tech Briefs, November 1995. Volume 19, No. 11

    Science.gov (United States)

    1995-01-01

    The contents include: 1) Mission Accomplished; 2) Resource Report: Marshall Space Flight Center; 3) NASA 1995 Software of the Year Award; 4) Microbolometers Based on Epitaxial YBa2Cu3O(sub 7-x) Thin Films; 5) Garnet Random-Access Memory; 6) Fabrication of SNS Weak Links on SOS Substrates; 7) High-Voltage MOSFET Switching Circuit; 8) Asymmetric Switching for a PWM H-Bridge Power Circuit; 9) Better Ohmic Contacts for InP Semiconductor Devices; 10) Low-Bandgap Thermovoltaic Materials and Devices; 11) Digital Frequency-Differencing Circuit; 12) Imaging Magnetometer; 13) Computer-Assisted Monitoring of a Complex System; 14) Buffered Telemetry Demodulator; 15) Compact Multifunction Inspection Head; 16) Optical Detection of Fractures in Ceramic Diaphragms; 17) Eddy-Current Detection of Cracks in Reinforced Carbon/Carbon; 18) Apparent Thermal Conductivity of Multilayer Insulation; 19) Optimizing Misch-Metal Compositions in Metal Hydride Anodes; 20) Device for Sampling Surface Contamination; 21) Probabilistic Failure Assessment for Fatigue; 22) Probabilistic Fatigue and Flaw-Propagation Analysis; 23) Windows Program for Driving the TDU-850 Printer; 24) Subband/Transform MATLAB Functions for Processing Images; 25) Computing Equilibrium Chemical Compositions; 26) Program Processes Thermocouple Readings; 27) ICAN-Second-Generation Integrated Composite Analyzer; 28) Integrated Composite Analyzer with Damping Capabilities; 29) Computing Efficiency of Transfer of Microwave Power; 30) Program Calculates Power Demands of Electronic Designs; 31) Cost-Estimation Program; 32) Program Estimates Areas Required by Electronic Designs; 33) Program to Balance Mapped Turbopump Assemblies; 34) BiblioTech; 35) Controlling Mirror Tilt With a Bimorph Actuator; 36) Burst-Disk Device Simulates Effect of Pyrotechnic Device; 37) Bearing-Mounting Concept Accommodates Thermal Expansion; 38) Parallel-Plate Acoustic Absorbers for Hot Environments; 39) Adjustable-Length Strut Withstands Large Cyclic

  7. Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk

    Directory of Open Access Journals (Sweden)

    James Wilton

    2016-06-01

    Full Text Available Introduction: Identifying appropriate pre-exposure prophylaxis (PrEP candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM, to identify “optimal” candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Methods: Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify “optimal” candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM, perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Results: Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were “optimal” candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3–2.2 and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2–2.3. The proportion of men who were “optimal” candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26. In our full cascade, a very low proportion (5.3% of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate

  8. Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk.

    Science.gov (United States)

    Wilton, James; Kain, Taylor; Fowler, Shawn; Hart, Trevor A; Grennan, Troy; Maxwell, John; Tan, Darrell Hs

    2016-01-01

    Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify "optimal" candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify "optimal" candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM), perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were "optimal" candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3-2.2) and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2-2.3). The proportion of men who were "optimal" candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26). In our full cascade, a very low proportion (5.3%) of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate-to-high HIV risk, 23.6% were unaware of PrEP, 40.1% were not

  9. Introducing the Clean-Tech Adoption Model: A California Case Study

    NARCIS (Netherlands)

    Bijlveld, P.C. (Paul); Riezebos, P. (Peter); Wierstra, E. (Erik)

    2012-01-01

    Abstract. The Clean-Tech Adoption Model (C-TAM) explains the adoption process of clean technology. Based on the Unified Theory of Acceptance and Usage of Technology (UTAUT) combined with qualitative research and empirical data gathering, the model predicts adoption based on the perceived quality, ef

  10. The institutional arrangements of innovation: Antecedents and performance effects of trust in high-tech alliances

    NARCIS (Netherlands)

    Jong, G. de; Klein Woolthuis, R.J.A.

    2008-01-01

    In this study we investigate the institutional arrangements of innovation processes in high-tech alliances, focusing on the role of trust. A major strength of the research is the opportunity to address antecedents as well as performance effects of trust. The antecedents of interorganizational trust

  11. The institutional arrangements of innovation : Antecendents and performance effects of trust in high-tech alliances

    NARCIS (Netherlands)

    de Jong, G.; Klein Woolthuis, R.

    2008-01-01

    In this study we investigate the institutional arrangements of innovation processes in high-tech alliances, focusing on the role of trust. A major strength of the research is the opportunity to address antecedents as well as performance effects of trust. The antecedents of interorganizational trust

  12. Contract research and high-tech alliances : Vistas for future studies

    NARCIS (Netherlands)

    de Jong, Gjalt; Woolthuis, Rosalinde J. A. Klein

    2008-01-01

    This research note addresses the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. Contract research is strongly heterogeneous, that is, many different paradigms, concepts, definitions and measures exist. We discuss the most im

  13. Silicon Valley: Planet Startup : Disruptive Innovation, Passionate Entrepreneurship & High-tech Startups

    NARCIS (Netherlands)

    Ester, P.; Maas, A.

    2016-01-01

    For decades now, Silicon Valley has been the home of the future. It's the birthplace of the world's most successful high-tech companies-including Apple, Yahoo, Google, Facebook, Twitter, and many more. So what's the secret? What is it about Silicon Valley that fosters entrepreneurship and innovation

  14. Are You What You Eat? An inside Look at High-Tech Food

    Science.gov (United States)

    Miller, Roxanne Greitz

    2007-01-01

    If we abide by the familiar saying "you are what you eat," it is understandable that people may be concerned with the incredible advances in food science technology and their possible impacts on human health. For example, in recent years high-tech scientific processes such as genetic modification, irradiation, and cloning have all been used to…

  15. SciTech Clubs for Girls. [Final report], September 1, 1991--April 30, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Malamud, E.; Diaz, O.; Cox, J.

    1994-12-31

    The program of SciTech Clubs for Girls and its progress are described. This is a program that promotes the learning of science and mathematics by girls in the age range of 9 to 13 years through the process of building exhibits and learning from local professionals. A list of exhibits and a critique of the program are given.

  16. AspenTech to Provide VPS for CNOOC-Shell Nanhai Petrochemicals Complex

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    @@ AspenTech, a US supplier of software and services to the process industries, recently announced it has been awarded a contract to supply a series of operator training simulators for the US$4.3 billion Nanhai Petrochemicals Project of CNOOC-Shell Petrochemical Company (CSPC)at Daya Bay in Huizhou City in South China's Guangdong Province.

  17. Determining Studies Conducted upon Individuals with Autism Spectrum Disorder Using High-Tech Devices

    Science.gov (United States)

    Eliçin, Özge; Kaya, Ali

    2017-01-01

    This study explores 67 experimental research articles written about children with Autism Spectrum Disorder using high-tech devices. The studies in this research were accessed through EBSCO, Academic Search Complete, ERIC, and Uludag University online search engines using keywords such as "autism and technology", "autism and…

  18. The Virginia Tech Shootings: Implications for Crisis Communication in Educational Settings

    Science.gov (United States)

    Barker, Gina G.; Yoder, Mollie E.

    2012-01-01

    By examining Virginia Tech's crisis communication during and after the shootings on April 16, 2007, valuable insights were gained that may be applied to current crisis communication models. This article addresses the unique characteristics of educational institutions and the need for comprehensive emergency communication strategies and on-site…

  19. Individualized Math Problems in Logarithms. Oregon Vo-Tech Mathematics Problem Sets.

    Science.gov (United States)

    Cosler, Norma, Ed.

    THis is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume includes problems involving logarithms, exponents, and…

  20. Single-tooth replacement by osseointegrated Astra Tech dental implants: a 2-year report

    DEFF Research Database (Denmark)

    Karlsson, U; Gotfredsen, K; Olsson, C

    1998-01-01

    This study presents the outcome of single-tooth restorations supported by Astra Tech single-tooth implants followed for 2 years. Forty-seven implants were placed in the same number of patients. Forty-three patients attended the second recall visit, and none of the evaluated implants have been...

  1. China’s comparative advantage still in low-tech manufacturing sector

    Institute of Scientific and Technical Information of China (English)

    文东伟; 冼国明

    2009-01-01

    This paper represents an attempt to estimate the level of vertical specialization in China’s manufacturing industry using China’s input-output tables (1995-2005) compiled by the OECD; describe the trends of evolution in the trade competitiveness of China’s manufacturing industry using the 1995-2006 trade data of 24 Chinese industries; and examine the key factors affecting the trade competitiveness of China’s manufacturing industry in accordance with the analytical framework of Hummels et al (2001). The estimation results indicate that i) the rapid increase in the vertical specialization levels of China’s merchandise sectors (especially the high-tech manufacturing sector) has to some extent explained the explosive growth of China’s exports (especially high-tech exports) in recent years; ii) there have been no substantive changes in China’s comparative advantages. Such advantages are still attributed to the low-tech manufacturing sector. However, the comparative advantage and trade competitiveness of the high-tech manufacturing sector have been on the rise; iii) vertical specialization has signif icantly enhanced the trade competitiveness of China’s manufacturing industry. Foreign market dependence, domestic intermediate input intensity and R&D intensity have an obvious promoting effect on the trade competitiveness of China’s manufacturing industry.

  2. Design of Demand Driven Return Supply Chain for High-Tech Products

    NARCIS (Netherlands)

    Ashayeri, J.; Tuzkaya, G.

    2010-01-01

    Many high-tech supply chain operate in a context of high process and market uncertainties due to shorter product life cycles. When introducing a new product, a company must manage the cost of supply, including the cost of returns over its short life cycle. The returns distribution looks like a negat

  3. New Horizontal Merger Guidelines Indicate Greater Scrutiny of High Tech and Pharmaceutical Transactions

    OpenAIRE

    Janet McDavid; Eric Stock

    2010-01-01

    It also indicates greater Agency scrutiny of such transactions in industries characterized by differentiated products and high levels of R&D spendingâ۠such as the high tech and pharmaceutical industries. Janet McDavid & Eric Stock (Hogan Lovells)

  4. TOOLS TO MINIMIZE RISK UNDER DEVELOPMENT OF HIGH-TECH PRODUCTS

    OpenAIRE

    AVDONIN BORIS N.; BATKOVSKY ALEXANDR M.; BATKOVSKY MIKHAIL A.

    2014-01-01

    The article describes the methodological bases and the economic and mathematical tools to minimize technological risks developing hightech products. A new, more efficient organization of the process of developing high-tech products, as well as tools for assessing the technical and economic efficiency of new technologies introduced on manufacturers of these products is offered.

  5. Investment in High-Tech Industries : An Example from the LCD Industry

    NARCIS (Netherlands)

    Huisman, K.J.M.; Kort, P.M.; Plasmans, J.E.J.

    2007-01-01

    This paper considers a representative firm taking investment decisions in a high-tech environment where different generations of products are invented over time. First, we develop a real options investment model in which, according to standard practice, the sales price and the unit production cost b

  6. Bazaarvoice: Applying Traditional Merger Analysis to a Dynamic High-Tech Market

    OpenAIRE

    James Fishkin

    2014-01-01

    No one should be surprised that the government will investigate mergers involving products in a high-tech industry utilizing the same Horizontal Merger Guidelines that apply to all merger investigationsâ۠regardless of the industry. James A. Fishkin (Dechert LLP)

  7. Knowledge virtualization and local connectedness among smart high-tech companies

    NARCIS (Netherlands)

    Van Geenhuizen, M.S.; Nijkamp, P.

    2011-01-01

    Smart high-tech companies are characterized by knowledge intensity and open innovation. Even when these companies emerge in spatial clusters or dense urban places, they may utilize knowledge networks on a global scale. However, there is not much insight into the factors that shape knowledge networks

  8. Sims to Teen Second Life: Transition of the SimSavvy Girls to Tech Savvy Isle

    Science.gov (United States)

    Johnson, Barbara Z.; King, Elizabeth; Hayes, Elisabeth

    2008-01-01

    In its second year, the Tech Savvy Girls Project adopted "Teen Second Life" as a platform for interest-driven learning and designed projects and objects around themes important to them and their futures as technology-using, creative people. By using the building tools in an open-ended virtual world, they were able to pursue interests common to…

  9. Utilising "Low Tech" Analytical Frameworks to Analyse Dyslexic Caribbean Students' Classroom Narratives

    Science.gov (United States)

    Blackman, Stacey

    2007-01-01

    The cognitions of Caribbean students with dyslexia are explored as part of an embedded multiple case study approach to teaching and learning at two secondary schools on the island of Barbados. This exploration employed "low tech" approaches to analyse what pupils had said in interviews using a Miles and Huberman (1994) framework.…

  10. The content and role of formal contracts in high-tech alliances

    NARCIS (Netherlands)

    Jong, G. de; Klein Woolthuis, R.J.A.

    2009-01-01

    In this study we investigate the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. The design of a formal agreement is one of the most important strategic decisions for alliance partners. Drawing upon transaction cost arguments

  11. Student chefs debut at Virginia Tech's Donaldson Brown Hotel and Conference Center

    OpenAIRE

    Felker, Susan B.

    2004-01-01

    The leap from graduation to that first full-time job is often daunting to college seniors, but that transition will be much easier for students in the Department of Hospitality and Tourism Management (HTM) program at Virginia Tech's Pamplin College of Business, thanks to hands-on labs at the university's Donaldson Brown Hotel and Conference Center.

  12. Virginia Tech Residence Hall Federation recognized with multiple awards at annual conference

    OpenAIRE

    Gehrt, Katie

    2009-01-01

    On Feb. 8, 2009, the Virginia Tech Residence Hall Federation took home five awards at the 2009 Virginia Association of College and University Residence Halls (VACURH) conference, held this year at The University of Virginia-Wise, located in Wise, Va.

  13. Application Model of New Agricultural Hotline Sci-tech Information Service System in Beijing

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    To further promote information construction in rural areas and popularize agricultural information service,we introduced the content of new agricultural hotline sci-tech information service system construction,summed up application effect of the system,analyzed advantages and existing problems in the system development,and put forward countermeasures for its further development.

  14. [Ways to optimize working conditions of medical personnel servicing modern hi-tech medical equipment].

    Science.gov (United States)

    Kravchenko, O K

    2007-01-01

    The author analyzed health state of medical personnel through various parameters. Hygienic characteristics of work conditions for medical personnel subjected to physical factors when servicing modern hi-tech medical equipment are presented. Occupational groups at high risk are defined. The article covers main directions in improving work conditions and preserving health for medical personnel in these groups.

  15. The Virginia Tech Shootings: Implications for Crisis Communication in Educational Settings

    Science.gov (United States)

    Barker, Gina G.; Yoder, Mollie E.

    2012-01-01

    By examining Virginia Tech's crisis communication during and after the shootings on April 16, 2007, valuable insights were gained that may be applied to current crisis communication models. This article addresses the unique characteristics of educational institutions and the need for comprehensive emergency communication strategies and on-site…

  16. A World of Competitors: Assessing the US High-Tech Advantage and the Process of Globalisation

    Science.gov (United States)

    Douglass, John Aubrey

    2008-01-01

    Research universities throughout the world are part of a larger effort by countries to bolster science and technological innovation and compete economically. The United States remains highly competitive as a source of high-tech innovation because of a number of market positions, many the results of long-term investments in institutions (such as…

  17. New partnership between Virginia Tech Transportation Institute and Center for Injury Biomechanics receives first research grant

    OpenAIRE

    Box, Sherri

    2009-01-01

    A team of three Virginia Tech faculty members -- Stefan Duma, Warren Hardy, and H. Clay Gabler -- was recently awarded $2.6 million from U.S. Army Research Acquisition Activity to study the biomechanics of head, neck, and chest injury prevention for soldiers.

  18. The content and role of formal contracts in high-tech alliances

    NARCIS (Netherlands)

    de Jong, Gjalt; Woolthuis, Rosalinde Ja Klein

    2009-01-01

    In this study we investigate the governance structure of innovation processes in high-tech alliances, focusing on the content and role of formal contracts. The design of a formal agreement is one of the most important strategic decisions for alliance partners. Drawing upon transaction cost arguments

  19. Organizational Attributes and Learning beyond the Boundaries: Comparative Case Studies of Two High-Tech Firms

    Science.gov (United States)

    Zhong, Jing; Wu, Sizong; Li, Jun

    2008-01-01

    This study compares two high-tech firms in terms of their differences in organizational characteristics and learning activities beyond the boundaries. It finds that the larger company continuously develops new technology to achieve long-term survival through a balance between exploration and exploitation while the smaller enterprise grows quickly…

  20. Reformulating General Engineering and Biological Systems Engineering Programs at Virginia Tech

    Science.gov (United States)

    Lohani, Vinod K.; Wolfe, Mary Leigh; Wildman, Terry; Mallikarjunan, Kumar; Connor, Jeffrey

    2011-01-01

    In 2004, a group of engineering and education faculty at Virginia Tech received a major curriculum reform and engineering education research grant under the department-level reform (DLR) program of the NSF. This DLR project laid the foundation of sponsored research in engineering education in the Department of Engineering Education. The DLR…

  1. Virginia Tech's Leonard K. Peters To Head Pacific Northwest National Laboratory

    OpenAIRE

    Trulove, Susan

    2003-01-01

    Leonard K. Peters, vice provost for research at Virginia Tech, will become Battelle senior vice president and director of the Pacific Northwest National Laboratory in Richland, Wash. The announcement was issued at time today by Carl Kohrt, CEO of Battelle. Peters assumes his new position on April 1.

  2. Virginia Tech's Board Of Visitors Appointed Two College Of Natural Resources Professors To Professorships

    OpenAIRE

    Davis, Lynn

    2003-01-01

    The Virginia Tech Board of Visitors has appointed Donald Orth the Thomas H. Jones Professor of Fisheries and Wildlife Sciences and Frederick Kamke the Thomas M. Brooks Professor of Wood Sciences and Forest Products. Orth and Kamke are on the faculty of the College of Natural Resources.

  3. Spaces of Innovation: Experiences from Two Small High-Tech Firms

    Science.gov (United States)

    Heiskanen, Tuula; Heiskanen, Hannu

    2011-01-01

    Purpose: By comparing two small high-tech firms specialising in medical technology this article seeks to answer the following questions: What are the key characteristics of innovation processes in the case firms? How do the mutual relationships between mental, social and physical spaces explain the different pathways in the innovation processes in…

  4. Design of Demand Driven Return Supply Chain for High-Tech Products

    NARCIS (Netherlands)

    Ashayeri, J.; Tuzkaya, G.

    2010-01-01

    Many high-tech supply chain operate in a context of high process and market uncertainties due to shorter product life cycles. When introducing a new product, a company must manage the cost of supply, including the cost of returns over its short life cycle. The returns distribution looks like a

  5. Worker participation - the Netherlands

    NARCIS (Netherlands)

    Kwantes, J.H.

    2014-01-01

    Worker participation relates to the involvement of workers in the management decision-making processes. In this article attention is focused on worker participation related to occupational safety and health in the Netherlands. Worker participation can refer either to direct or indirect participation

  6. Practice and Exploration of Rural Sci-tech Service Supermarket:A Case Study of Jurong Economic Forest and Fruit Industrial Branch

    Institute of Scientific and Technical Information of China (English)

    Weizhong; LIU; Yabo; LIU; Jianying; ZHANG; Nini; MAO; Zhijian; WANG

    2013-01-01

    The rural sci-tech supermarket in Jiangsu Province is an innovative model of rural sci-tech service. With reference to the concept of modern commodity supermarket, this model integrates variety, technology and achievement information into the sci-tech supermarket platform, provides various agricultural sci-tech services, and improves farmers recognition and acceptance of science and technology, so as to accelerate conversion of scientific and technological achievements and demonstration and popularization of new varieties, new technologies and new models. This paper analyzes practice of Jurong economic forest and fruit industrial branch and presents recommendations for building Jiangsu rural sci-tech service supermarket.

  7. Etiologic factors related to unsatisfactory ThinPrep® cervical cytology: Evaluation and potential solutions to improve

    Directory of Open Access Journals (Sweden)

    Tatyana Kalinicheva

    2015-01-01

    Full Text Available Background: In cervical cytology, the unsatisfactory rates for ThinPrep (TP are slightly higher compared to SurePath. We examined various causes and explored potential for resolution of this discrepancy. Materials and Methods: Totally, 19,422 cases were reviewed and 1000 unsatisfactory specimens were selected and analyzed. 531 specimens were available for wash protocol. Out of 114 unsatisfactory specimens associated with atrophic cellular changes (ACC, 48 were resubmitted by provider and reevaluated. Results: Lubricant and lubricant-like debris/contamination (LUBE was the most common cause of unsatisfactory specimens (68%; 681/1000 followed by blood (7.5%; ACC only (without other interfering factors (2.4%; inflammation (3.0%; and combinations thereof (1.9%. 11.5% showed scant cellularity without an identifiable cause. 3.3% were virtually acellular. Wash protocol improved cellularity in 48% (256/531 of cases. However, only 29% (73/256 of those were satisfactory (with more than 5000 cells. Quantitative reduction in LUBE after wash protocol varied with different morphological subtypes. Interpretation patterns on satisfactory specimens after wash protocol were comparable to the results on selected cohort of specimens during the same study period. Out of 114 ACC, wash protocol was performed on 68 ACC specimens leading to satisfactory TP in 24% (16/68. Totally, 48 cases reported as unsatisfactory with ACC, were resubmitted by the providers between 2 weeks and 2 years. 44 (92% showed increased cellularity, out of which 52% (23/44 did not show ACC. Conclusion: LUBE was the most common cause of unsatisfactory TP in addition to interference by blood and association with atrophic changes. Knowing the morphological spectrum of LUBE would help to identify it as the cause of "unsatisfactory" TP. Communicating the cause of unsatisfactory TP such as LUBE, ACC, and blood would hint the provider to take appropriate precaution during submission of the repeat

  8. Flanking region variation of ForenSeq™ DNA Signature Prep Kit STR and SNP loci in Yavapai Native Americans.

    Science.gov (United States)

    Wendt, Frank R; King, Jonathan L; Novroski, Nicole M M; Churchill, Jennifer D; Ng, Jillian; Oldt, Robert F; McCulloh, Kelly L; Weise, Jessica A; Smith, David Glenn; Kanthaswamy, Sreetharan; Budowle, Bruce

    2017-02-27

    Massively parallel sequencing (MPS) offers advantages over current capillary electrophoresis-based analysis of short tandem repeat (STR) loci for human identification testing. In particular STR repeat motif sequence information can be obtained, thereby increasing the discrimination power of some loci. While sequence variation within the repeat region is observed relatively frequently in some of the commonly used STRs, there is an additional degree of variation found in the flanking regions adjacent to the repeat motif. Repeat motif and flanking region sequence variation have been described for major population groups, however, not for more isolated populations. Flanking region sequence variation in STR and single nucleotide polymorphism (SNP) loci in the Yavapai population was analyzed using the ForenSeq™ DNA Signature Prep Kit and STRait Razor v2s. Seven and 14 autosomal STRs and identity-informative single nucleotide polymorphisms (iiSNPs), respectively, had some degree of flanking region variation. Three and four of these identity-informative loci, respectively, showed ≥5% increase in expected heterozygosity. The combined length- and sequence-based random match probabilities (RMPs) for 27 autosomal STRs were 6.11×10(-26) and 2.79×10(-29), respectively. When combined with 94 iiSNPs (a subset of which became microhaplotypes) the combined RMP was 5.49×10(-63). Analysis of length-based and sequence-based autosomal STRs in STRUCTURE indicated that the Yavapai are most similar to the Hispanic population. While producing minimal increase in X- and Y-STR discrimination potential, access to flanking region data enabled identification of one novel X-STR and three Y-STR alleles relative to previous reports. Five ancestry-informative SNPs (aiSNPs) and two phenotype-informative SNPs (piSNPs) exhibited notable flanking region variation.

  9. Application of ThinPrep Bronchial Brushing Cytology in the Early Diagnosis of Lung Cancer: A Retrospective Study

    Science.gov (United States)

    Liu, Chaoying; Wen, Zhongmei; Li, Yang; Peng, Liping

    2014-01-01

    The majority of lung cancer patients are diagnosed at advanced stages of disease. This study evaluated the diagnostic value of ThinPrep (TP) bronchial brushing cytology in lung cancer. A total of 595 patients with suspicious lung cancer were enrolled in this study. The bronchial brushing samples were prepared by TP. The data were then compared to histology of lung tissue samples. Histologically, 479 of these 595 patients were diagnosed with lung cancer, including 223 cases of lung squamous cell carcinoma (SCC), 77 cases of lung adenocarcinoma (ADC), and 152 cases of small cell lung carcinoma (SCLC). The TP cytology revealed a total of 460 cases of lung cancer (including 232 SCCs, 91 ADCs, and 108 SCLCs). The TP cytological technique had 87.06% sensitivity and 62.93% specificity in the diagnosis of lung cancer. Specifically, TP cytology confirmed 195 of 223 SCCs, 47 of 77 ADCs, and 94 of 152 SCLCs. The TP cytology showed 87.44% sensitivity and 90.05% specificity for the diagnosis of SCC, with a Matthew's correlation coefficient (MCC) of 0.820; while the sensitivity was reduced to 61.04% and the specificity was 90.93% for the diagnosis of ADC, with a MCC of 0.464. For the diagnosis of SCLC, the sensitivity was 61.84% and the specificity was 96.84%, with a MCC of 0.648. Thus, this study demonstrated the usefulness of TP bronchial brushing cytology in the early diagnosis of lung cancer, especially the early stage of lung SCC. A prospective clinical trial will verify these data before being translated into the clinic. PMID:24759600

  10. Decision Making In A High-Tech World: Automation Bias and Countermeasures

    Science.gov (United States)

    Mosier, Kathleen L.; Skitka, Linda J.; Burdick, Mark R.; Heers, Susan T.; Rosekind, Mark R. (Technical Monitor)

    1996-01-01

    Automated decision aids and decision support systems have become essential tools in many high-tech environments. In aviation, for example, flight management systems computers not only fly the aircraft, but also calculate fuel efficient paths, detect and diagnose system malfunctions and abnormalities, and recommend or carry out decisions. Air Traffic Controllers will soon be utilizing decision support tools to help them predict and detect potential conflicts and to generate clearances. Other fields as disparate as nuclear power plants and medical diagnostics are similarly becoming more and more automated. Ideally, the combination of human decision maker and automated decision aid should result in a high-performing team, maximizing the advantages of additional cognitive and observational power in the decision-making process. In reality, however, the presence of these aids often short-circuits the way that even very experienced decision makers have traditionally handled tasks and made decisions, and introduces opportunities for new decision heuristics and biases. Results of recent research investigating the use of automated aids have indicated the presence of automation bias, that is, errors made when decision makers rely on automated cues as a heuristic replacement for vigilant information seeking and processing. Automation commission errors, i.e., errors made when decision makers inappropriately follow an automated directive, or automation omission errors, i.e., errors made when humans fail to take action or notice a problem because an automated aid fails to inform them, can result from this tendency. Evidence of the tendency to make automation-related omission and commission errors has been found in pilot self reports, in studies using pilots in flight simulations, and in non-flight decision making contexts with student samples. Considerable research has found that increasing social accountability can successfully ameliorate a broad array of cognitive biases and

  11. User participation in implementation

    DEFF Research Database (Denmark)

    Fleron, Benedicte; Rasmussen, Rasmus; Simonsen, Jesper

    2012-01-01

    Systems development has been claimed to benefit from user participation, yet user participation in implementation activities may be more common and is a growing focus of participatory-design work. We investigate the effect of the extensive user participation in the implementation of a clinical...... system by empirically analyzing how management, participating staff, and non-participating staff view the implementation process with respect to areas that have previously been linked to user participation such as system quality, emergent interactions, and psychological buy-in. The participating staff...... experienced more uncertainty and frustration than management and non-participating staff, especially concerning how to run an implementation process and how to understand and utilize the configuration possibilities of the system. This suggests that user participation in implementation introduces a need...

  12. Liquid-based cervical cytology using ThinPrep technology: weighing the pros and cons in a cost-effectiveness analysis.

    Science.gov (United States)

    de Bekker-Grob, Esther W; de Kok, Inge M C M; Bulten, Johan; van Rosmalen, Joost; Vedder, Judith E M; Arbyn, Marc; Klinkhamer, Paul J J M; Siebers, Albertus G; van Ballegooijen, Marjolein

    2012-08-01

    Cervical cancer screening with liquid-based cytology (LBC) has been developed as an alternative to the conventional Papanicolaou (CP) smear. Cost-effectiveness is one of the issues when evaluating LBC. Based on the results of a Dutch randomised controlled trial, we conducted cost-effectiveness threshold analyses to investigate under what circumstances manually screened ThinPrep LBC is cost-effective for screening. The MISCAN-Cervix microsimulation model and data from the Dutch NETHCON trial (including 89,784 women) were used to estimate the costs and (quality-adjusted) life years ((QA)LYs) gained for EU screening schedules, varying cost-effectiveness threshold values. Screening strategies were primary cytological screening with LBC or CP, and triage with human papillomavirus (HPV) testing. Threshold analyses showed that screening with LBC as a primary test can be cost-effective if LBC is less than 3.2 more costly per test than CP, if the sensitivity of LBC is at least 3-5 % points higher than CP, if the quality of life for women in triage follow-up is only 0.39, or if the rate of inadequate CP smears is at least 16.2 %. Regarding test characteristics and costs of LBC and CP, only under certain conditions will a change from CP to manually screened ThinPrep LBC be cost-effective. If none of these conditions are met, implementation of manually screened ThinPrep LBC seems warranted only if there are advantages other than cost-effectiveness. Further research is needed to establish whether other LBC systems will be more favorable with regard to cost-effectiveness.

  13. Effect of glacial acetic acid treatment of cervical ThinPrep specimens on HPV DNA detection with the cobas 4800 HPV test.

    Science.gov (United States)

    McMenamin, M; McKenna, M

    2013-10-01

    Cytology laboratories in the UK routinely treat unsatisfactory cervical liquid-based cytology (LBC) specimens with glacial acetic acid (GAA) to reduce the unsatisfactory rate. However, there is limited published data on the effect of GAA reprocessing on the molecular detection of human papillomavirus (HPV). The aim of this study was to assess the impact of GAA treatment of cervical ThinPrep(®) samples on HPV detection with the cobas(®) 4800 HPV Test (Roche Molecular Systems, Pleasanton, CA, USA). Residual ThinPrep samples (n = 121) were selected to provide a range of typical cytology results and enrich the study samples for HPV positivity. Specimens were equally split into two fractions: one part treated with 10% GAA and the other part left untreated. All samples were HPV tested using the cobas 4800 HPV Test, which simultaneously detects a total of 14 high-risk HPV (hrHPV) genotypes and individually identifies HPV16 and HPV18. The HPV positive/negative status of tested samples determined the level of agreement between treated and untreated fractions; one sample failed owing to detection of a clot by the instrument during pipetting, leaving 120 samples in the study. Statistical analysis was performed using an unweighted kappa. Analysis of overall HPV positivity showed 97.5% (117/120) agreement between the treated and untreated fractions with a kappa value of 0.95. There were 63/65 (96.9%) concordant HPV positive and 54/55 (98.2%) concordant HPV negative results. In addition to the three discordant results for overall HPV positivity, there were three HPV type-specific discrepancies giving a total of 114/120 concordant HPV results (95% agreement). Glacial acetic acid (GAA) treatment of cervical ThinPrep specimens does not have significant adverse affects on HPV detection with the cobas 4800 HPV Test. © 2013 John Wiley & Sons Ltd.

  14. Connecting Participant Observation Positions

    DEFF Research Database (Denmark)

    McCurdy, Patrick; Uldam, Julie

    2014-01-01

    In this article, we argue for the importance of considering participant observation roles in relation to both insider/outsider and overt/covert roles. Through combining key academic debates on participant observation, which have separately considered insider/outsider and overt/covert participant...... observation, we develop a reflexive framework to assist researchers in (1) locating the type of participant observation research; (2) identifying implications of participant observation for both the research and the subjects under study; and (3) reflecting on how one’s role as participant observer shifts over...

  15. Od bazy bibliograficznej do pe?notekstowej ? wsp??praca og?lnopolskiego Konsorcjum BazTech

    OpenAIRE

    2015-01-01

    W artykule przedstawiono baz? BazTech indeksuj?c? zawarto?? polskich czasopism technicznych. W szczeg?lno?ci om?wiono: zas?b bazy, rodzaje rekord?w, sposoby dost?pu i prezentacji zawartych w bazie informacji. Om?wiono etapy przekszta?cania bazy z bibliograficznej-abstraktowej w pe?notekstow?. Zaprezentowano tw?rc?w bazy czyli wsp??pracuj?ce, od prawie 20 lat, tworz?ce Konsorcjum BazTech, biblioteki wy?szych uczelni technicznych i instytut?w naukowych. The article presents the BazTech da...

  16. Zero transmission of HIV– “Still a long way to go” An Update on TasP : PrEP and PEP of HIV infection

    OpenAIRE

    Hiremath, Ravishekar N; Kamble, Manjunath; Bhalla, Sandeep; Ghodke, Sandhya; R K Chaudhary

    2014-01-01

    AIDS emerged as one of the most important public health issues of the late twentieth and early twenty-first centuries and is now one of the leading causes of global morbidity and mortality. The AIDS epidemic has prompted wide-reaching changes in public health, clinical practice, and scientific research, and has had a great impact upon societies throughout the world. This review article gives an in site into updates on TasP (Treatment as prevention), PrEP (pre-exposure prophylaxis) and PEP (Po...

  17. Lactacidemia en el umbral anaeróbico. Estudio en varones prepúberes de escuelas deportivas de fútbol.

    OpenAIRE

    2004-01-01

    RESUMEN El objetivo principal es conocer la conducta del lactato en sangre. Situación bibliográfica. Estructurada en cinco apartados: reservas energéticas y límites metabólicos, la regulación ácido-base, el metabolismo del lactato, el umbral anaeróbico y las diferencias existentes entre niños y adultos. Nos centramos en los menores niveles de lacticemia en los niños, el mayor umbral anaeróbico en prepúberes frente a adultos y las diferencias de adaptación del metabolismo glucolítico....

  18. Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP.

    Directory of Open Access Journals (Sweden)

    Albert Y Liu

    Full Text Available Pre-exposure prophylaxis (PrEP trials using tenofovir-based regimens have demonstrated that high levels of adherence are required to evaluate efficacy; the incorporation of objective biomarkers of adherence in trial design has been essential to interpretation, given the inaccuracy of self-report. Antiretroviral measurements in scalp hair have been useful as a marker of long-term exposure in the HIV treatment setting, and hair samples are relatively easy and inexpensive to collect, transport, and store for analysis. To evaluate the relationship between dose and tenofovir concentrations in hair, we examined the dose proportionality of tenofovir in hair in healthy, HIV-uninfected adults.A phase I, crossover pharmacokinetic study was performed in 24 HIV-negative adults receiving directly-observed oral tenofovir tablets administered 2, 4, and 7 doses/week for 6 weeks, with a ≥3-week break between periods. Small samples of hair were collected after each six-week period and analyzed for tenofovir concentrations. Geometric-mean-ratios compared levels between each pair of dosing conditions. Intensive plasma pharmacokinetic studies were performed during the daily-dosing period to calculate areas-under-the-time-concentration curves (AUCs.Over 90% of doses were observed per protocol. Median tenofovir concentrations in hair increased monotonically with dose. A log-linear relationship was seen between dose and hair levels, with an estimated 76% (95% CI 60-93% increase in hair level per 2-fold dose increase. Tenofovir plasma AUCs modestly predicted drug concentrations in hair.This study found a strong linear relationship between frequency of dosing and tenofovir levels in scalp hair. The analysis of quantitative drug levels in hair has the potential to improve adherence measurement in the PrEP field and may be helpful in determining exposure thresholds for protection and explaining failures in PrEP trials. Hair measures for adherence monitoring may also

  19. 中小企业技术创新对成长性影响——科技型企业不同于非科技型企业?%Impact of tech - innovation on growth : are high - tech SMEs different from non - high - tech SMEs?

    Institute of Scientific and Technical Information of China (English)

    陈晓红; 马鸿烈

    2012-01-01

    Tech innovation has important meaning on the growth of high - tech and non - high - tech SMEs, based on 437 Chinese lis- ted SMEs, this paper initial build tech - innovation model to these two types of enterprise respectively, and analyze impact of their tech - innovation on growth. Result shows that greater R&D intensity, better enterprise tech - innovation environment, more patent number and greater human resource input, the better of SMEs tech - innovation ability; for high - teeh SMEs, relationship between tech - inno- vation and growth is linear, while for non - high - tech SMEs, the relevance is not obvious, for this situation, combining practical con- dition, this paper provide advice for SMEs development.%技术创新对科技型和非科技型中小企业成长性的作用具有一定重要意义,基于414家中小上市公司数据,本文首次针对两类企业分别构建了技术创新模型,分析技术创新对二者成长性的影响。结果表明:研发投人程度越大,企业创新环境越好,专利数量越多,人力资源的投入强度越大的中小企业技术创新能力越强;对于科技型中小企业,其技术创新与成长性呈显著正相关关系,而非科技型中小企业其相关性不明显,针对该情况,本文结合实际现状对中小企业的发展提出了建议。

  20. Participation and agency

    DEFF Research Database (Denmark)

    Jamison, Andrew

    2004-01-01

    The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe.......The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe....

  1. Labor Force Participation Rate

    Data.gov (United States)

    City and County of Durham, North Carolina — This thematic map presents the labor force participation rate of working-age people in the United States in 2010. The 2010 Labor Force Participation Rate shows the...

  2. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Z > Participating in Clinical Trials: About Clinical Trials In This Topic About Clinical Trials Risks and Benefits ... of this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study ...

  3. Participation and agency

    DEFF Research Database (Denmark)

    Jamison, Andrew

    2004-01-01

    The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe.......The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe....

  4. Participation in adult learning

    DEFF Research Database (Denmark)

    Desjardins, Richard

    2010-01-01

    This entry presents an internationally comparative overview of adult learning patterns. Emphasis is placed on who is participating in adult learning and the observed unequal chances to participate. The entry covers three overarching questions that are central to participation research: a) What...

  5. Displacement Through Participation

    NARCIS (Netherlands)

    Huisman, Carla

    2014-01-01

    Citizen participation is often regarded as a means to increase local democracy. Seldom is participation viewed as a means to legitimate disruptive practices of states. However, participation can become a tool for the effective implementation of policy rather than a means to enhance justice, if no po

  6. 区域科技创新与科技金融耦合协调度评价研究%Research on Coupling Coordinated Degree Evaluation of Regional Sci-tech Innovation and Sci-tech Finance

    Institute of Scientific and Technical Information of China (English)

    徐玉莲; 王玉冬; 林艳

    2011-01-01

    The coupling coordinated development of sci-tech innovation and sci-tech finance is the important sup- port for regional knowledge economy growth. Based on the definition of sci-tech finance, analyzes the coupling rela- tionship between regional sci-tech innovation and sci-tech finance. The paper constructs the evaluation model of cou- piing coordinated degree, and uses the model to evaluate the coupling coordinated degrees of provincial regions in China. The results show that the coupling coordinated degrees are on the low side, the development of sci-tech fi- nance lags behind sci-tech innovation in most provinces, and the gaps of the coupling coordinated degrees in East Middle West regions are relatively significant. According to the result of evaluation, some policy suggestions to pro- mote the coupling coordinated development of sci-tech innovation and sci-tech finance are put forward. The re- search provides scientific basis and decision reference for the coordinated and sustainable development of regional sci-tech innovation and sci-tech finance.%科技创新与科技金融耦合协调发展对区域知识经济增长具有强有力的支撑作用。通过对科技金融内涵的界定和区域科技创新与科技金融的互动耦合关系分析,构建区域科技创新与科技金融耦合协调度评价模型,并运用我国省级区域统计数据,对其耦合协调度进行实证分析。实证研究结果表明:我国各省市科技创新与科技金融耦合协调度整体偏低;大部分省市科技金融滞后于科技创新发展;东、中、西部地区耦合协调度差距较为显著。据此给出我国区域科技创新与科技金融耦合协调发展的相关政策建议。

  7. Mapping eParticipation

    DEFF Research Database (Denmark)

    Rose, Jeremy; Sanford, Clive Carlton

    2007-01-01

    The emerging research area of eParticipation can be characterized as the study of technology-facilitated citizen participation in (democratic) deliberation and decision-making. Using conventional literature study techniques, we identify 105 articles that are considered to be highly relevant to eParticipation......, and methods. We extend the analysis to define four central research challenges for the field: understanding technology and participation; the strategic challenge; the design challenge; and the evaluation challenge. This article thus contributes to a developing account of eParticipation, which will help future...

  8. Study on the comprehensive advantage evaluation method of high-tech enterprises based on RBF artificial neural network

    Institute of Scientific and Technical Information of China (English)

    WANG Hong-qi; WANG Xue-yuan; TANG Yu

    2005-01-01

    This paper designs an intelligent evaluation approach using a Radial Basis Function (RBF) Artificial Neural Network. We based our approach on establishing a comprehensive advantage evaluating index system that offers scientific substance for creating a development plan and the strategic management of high-tech industry and regional cluslers of high-tech enterprises. Furthermore, this paper selects some typical high-tech enterprises' data to make comprehensive training on the network system. Meanwhile, the paper chooses some enterprises as testing samples to test the method, the result of which proves that this method is truly effective. The research of this paper provides a comprehensive advantage evaluating and managing method for high-tech enterprise.

  9. 菱科电子技术(中国)有限公司%Link Tech (China) Co.,Ltd

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Link Tech Co.,Ltd thought that the quality management should be a “overall” quality management,the emphasis lies in the “comprehensive”, and the point is “market”. We didn't acknowledge that the enter-prise scale has direct relation with management quality. Link Tech would adopted various methods toregister the “Top100 Chinese Electronic Enterprises for Quality” evaluation activity.

  10. Definition of a shortcut methodology for assessing flood-related Na-Tech risk

    Directory of Open Access Journals (Sweden)

    E. Marzo

    2012-11-01

    Full Text Available In this paper a qualitative methodology for the initial assessment of flood-related Na-Tech risk was developed as a screening tool to identify which situations require a much more expensive quantitative risk analysis (QRA. Through the definition of some suitable key hazard indicators (KHIs, the proposed methodology allows the identification of the Na-Tech risk level associated with a given situation; the analytical hierarchy process (AHP was used as a multi-criteria decision tool for the evaluation of such qualitative KHIs. The developed methodology was validated through two case studies by comparing the predicted risk levels with the results of much more detailed QRAs previously presented in literature and then applied to the real flood happened at Spolana a.s., Neratovice, Czech Republic in August 2002.

  11. A Concept of Constructing a Common Information Space for High Tech Programs Using Information Analytical Systems

    Science.gov (United States)

    Zakharova, Alexandra A.; Kolegova, Olga A.; Nekrasova, Maria E.

    2016-04-01

    The paper deals with the issues in program management used for engineering innovative products. The existing project management tools were analyzed. The aim is to develop a decision support system that takes into account the features of program management used for high-tech products: research intensity, a high level of technical risks, unpredictable results due to the impact of various external factors, availability of several implementing agencies. The need for involving experts and using intelligent techniques for information processing is demonstrated. A conceptual model of common information space to support communication between members of the collaboration on high-tech programs has been developed. The structure and objectives of the information analysis system “Geokhod” were formulated with the purpose to implement the conceptual model of common information space in the program “Development and production of new class mining equipment - “Geokhod”.

  12. Childbirth education in rural haiti: reviving low-tech teaching strategies.

    Science.gov (United States)

    Gibson, Martha; Bowles, Betty Carlson; Jansen, Lauren; Leach, Jane

    2013-01-01

    On a medical mission into rural mountainous regions of Haiti, the authors were charged with teaching safer childbirth practices to untrained, mostly illiterate traditional birth attendants (TBA) who spoke Haitian Creole. In this isolated region with no physician or accessible hospital, almost all births occur at home. With no electricity, safe water supply, or sanitation facilities, childbirth education was a challenge. Accustomed to electronic, high-tech teaching aids, these childbirth educators had to modify educational strategies for these extraordinary circumstances. A successful solution was to revive decades-old teaching techniques and visual aids once used in Lamaze classes. The purpose of this article is to describe the teaching environment, the target audience, and the low-tech approach to childbirth education in Haiti.

  13. An Optimized Grey Dynamic Model for Forecasting the Output of High-Tech Industry in China

    Directory of Open Access Journals (Sweden)

    Zheng-Xin Wang

    2014-01-01

    Full Text Available The grey dynamic model by convolution integral with the first-order derivative of the 1-AGO data and n series related, abbreviated as GDMC(1,n, performs well in modelling and forecasting of a grey system. To improve the modelling accuracy of GDMC(1,n, n interpolation coefficients (taken as unknown parameters are introduced into the background values of the n variables. The parameters optimization is formulated as a combinatorial optimization problem and is solved collectively using the particle swarm optimization algorithm. The optimized result has been verified by a case study of the economic output of high-tech industry in China. Comparisons of the obtained modelling results from the optimized GDMC(1,n model with the traditional one demonstrate that the optimal algorithm is a good alternative for parameters optimization of the GDMC(1,n model. The modelling results can assist the government in developing future policies regarding high-tech industry management.

  14. Using a Mixed Model to Evaluate Job Satisfaction in High-Tech Industries.

    Science.gov (United States)

    Tsai, Sang-Bing; Huang, Chih-Yao; Wang, Cheng-Kuang; Chen, Quan; Pan, Jingzhou; Wang, Ge; Wang, Jingan; Chin, Ta-Chia; Chang, Li-Chung

    2016-01-01

    R&D professionals are the impetus behind technological innovation, and their competitiveness and capability drive the growth of a company. However, high-tech industries have a chronic shortage of such indispensable professionals. Accordingly, reducing R&D personnel turnover has become a major human resource management challenge facing innovative companies. This study combined importance-performance analysis (IPA) with the decision-making trial and evaluation laboratory (DEMATEL) method to propose an IPA-DEMATEL model. Establishing this model involved three steps. First, an IPA was conducted to measure the importance of and satisfaction gained from job satisfaction criteria. Second, the DEMATEL method was used to determine the causal relationships of and interactive influence among the criteria. Third, a criteria model was constructed to evaluate job satisfaction of high-tech R&D personnel. On the basis of the findings, managerial suggestions are proposed.

  15. Forming system of strategic innovation management at high-tech engineering enterprises

    Science.gov (United States)

    Ergunova, O. T.; Lizunkov, V. G.; Malushko, E. Yu; Marchuk, V. I.; Ignatenko, A. Yu

    2017-02-01

    The article considers the processes of forming the strategic system of innovative activity management at the enterprises of a high-tech mechanical engineering complex (MEC) that are traditionally decisive in shaping the economic base of Russia. The authors proposed a method of designing a strategic system of innovative activity management at the MEC’s enterprises of the region which is based on the consideration of means and opportunities of the enterprise to implement intellectual activity. The proposed methodology and the empirical results constituted a ground for developing a system of strategic innovation management when performing the state-guaranteed order at the hi-tech MEC enterprises. Its implementation will help to reduce the level of uncertainty throughout the entire life cycle of an innovative activity product.

  16. PRODUCTION RISKS AND ECONOMIC HAZARDS OF MODERN HIGH-TECH INDUSTRIES

    Directory of Open Access Journals (Sweden)

    Khrustalev E. Y.

    2016-03-01

    Full Text Available The article shows that when the plans for the creation and production of modern high-tech innovative products for different purposes it is necessary to consider all possible risks and dangers that accompany modern innovative projects. New approaches to the planning of the development of science-intensive industries should ensure that the accounting and the management of risk situations of the financialeconomic, scientific-technical and industrialtechnological character. One of the promising directions of the domestic output of the industrial complex from its current unstable state is a strategic planning and forecasting of its activity, the development strategies should be based on an evaluation of available enterprise resources, the lack of which leads to stagnation. With active government support the company can successfully implement a strategy of stabilization and progress through cooperation and diversification of production and to make a technological breakthrough in creating high-tech products of new generation

  17. Improving Laboratory Efficiency by Automation of Preanalytic Processing of ThinPrep Specimens for Real-Time PCR High-Risk HPV Testing.

    Science.gov (United States)

    Barbieri, Daniela; Venturoli, Simona; Costa, Silvano; Landini, Maria Paola

    2016-06-01

    Cervical specimens collected in liquid-based cytology (LBC) media are the most common sample type used for high-risk human papillomavirus (HPV) testing. Since preanalytic steps such as vortexing and decapping vials, liquid transfer to a sample input tube with matching unique identifier, and recapping the original vials are required for processing LBC samples prior to running the Abbott RealTime High Risk HPV assay (Abbott, Wiesbaden, Germany), a full manual execution can be complicated, especially in high-throughput diagnostic contexts. Here, a custom-configured worktable setup for the Tecan Freedom EVO (Tecan, Männedorf, Switzerland) designed to automate and control preanalytic steps for ThinPrep (Hologic, Marlborough, MA) samples was used to evaluate the impact of automated versus manual preanalytics. Archival results for manual processing of 226 samples were compared with those obtained with the Tecan protocol, observing a very good overall concordance for final assay interpretation (95.6%). High overall agreement (100%) resulted also from retesting 99 samples by both the preanalytical protocols. High reproducibility was observed analyzing 23 randomly selected samples by automated preprocessing in triplicate. Hence, the new configuration of the Tecan platform translates the manual steps required to process ThinPrep specimens into automated operations, controls sample identification, and allows for saving hands-on time, while maintaining assay reproducibility and ensuring reliability of results, making it suitable for screening settings.

  18. Evaluation of the Illumina ForenSeq™ DNA Signature Prep Kit - MPS forensic application for the MiSeq FGx™ benchtop sequencer.

    Science.gov (United States)

    Xavier, Catarina; Parson, Walther

    2017-05-01

    Massively Parallel (Next Generation) Sequencing (MPS) technologies have recently been proven useful and successful in typing various markers relevant in forensic genetics, such as STRs, SNPs and mitochondrial genomes. Early studies investigated self-developed DNA libraries, commercially supplied kits are currently being made available to allow a smoother and gradual implementation of such technologies in forensic laboratories. The ForenSeq™ DNA Signature Prep Kit (Illumina, CA) is the first commercially available STR kit that can be used on the MiSeq FGx™ (Illumina, CA) benchtop high-throughput sequencer. This kit allows the simultaneous typing of 59 STRs and up to 172 SNPs in a single reaction and presents a short library preparation protocol adapted to contemporary forensic requirements. In this study, we evaluated the beta version of the ForenSeq DNA Signature Prep Kit MiSeq FGx system by investigating reproducibility, sensitivity, mixtures, concordance, casework-type and aDNA samples and found it to perform successfully, proving to be a robust method for future forensic applications. MPS brings the possibility of complex multiplexing, high sensitivity and sequencing resolution to forensics; however, the need for consensual directions on databasing, data storage and nomenclature must be taken into consideration. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. 11TH Annual Science and Engineering Technology Conference/DoD Tech Exposition

    Science.gov (United States)

    2010-04-15

    Technologies, Inc. Mr. John Maguire Georgia Tech Research Institute Mr. Roger Mann Lockheed Martin Corporation Dr. Todd Marek Scientific Research...Pandemic Disease Manmade Disasters Illegal Migration UNCLASSIFIED UNCLASSIFIED 5 60 Organizations are part of our Team!!! Public Safety Canada Transport...Resources (e.g., Illegal Fishing) • Pandemic Disease – HIV/AIDS • Insufficient Means to Confront Challenges •Dependence on Foreign Assistance 11.7

  20. A holistic model for matching high-tech hearing aid features to elderly patients.

    Science.gov (United States)

    Johnson, C E; Danhauer, J L; Krishnamurti, S

    2000-12-01

    Successful hearing aid fittings using high-technology features for elderly patients require consideration of factors beyond results obtained from routine audiologic evaluations. A holistic hearing aid selection, fitting, and evaluation approach that considers patient characteristics from communication, physical, psychological, and social assessment domains is presented here along with a checklist and flowcharts for matching high-tech hearing aid features to older persons who are hearing aid candidates.

  1. W kierunku bazy pełnotekstowej - inicjatywy BazTech

    OpenAIRE

    2009-01-01

    The paper presents the BazTech’s initiatives which lead to transforming the database from a bibliographic one into a full-text one. It points out the co-operation between ICM UW and journal publishers in the field of gaining full-text articles. It also discusses the formal procedures of the co-operation and the rules of proceeding within Konsorcjum BazTech.

  2. From novice to tech savvy teachers. A Report of Faculty Members’ Teaching with Technology Experiences

    Directory of Open Access Journals (Sweden)

    Jennie M. Hwang

    2011-06-01

    Full Text Available This study explores faculty motivations to adopt technologies for their courses, their current uses of technologies and perceptions of teaching with technologies, as well as their suggestions for how their institutions can best support them. In particular, this investigation compares novice and tech savvy teachers by looking at differences in the technologies they use, how they integrate these technologies in their courses, and the challenges they experience in doing so.

  3. BREAKING THROUGH THE "BRICK WALL" — USING AN INTERDISCIPLINARY STRATEGY TO MARKET HIGH-TECH PRODUCTS

    OpenAIRE

    ADAM PERRY TOW; Amit M. Joshi

    2011-01-01

    Marketing high-tech products poses challenges to classically trained marketers who may be unfamiliar with a product's underlying science or technology. Often such marketing teams, lacking scientific backgrounds, find it particularly difficult to interface with R&D and truly understand a product's inner workings — something we show to be critical to fully assessing a product for effective differentiation and marketing. By utilizing a novel marketing strategy, the Interdisciplinary Strategic Ma...

  4. Science and Technology Is Not Simply Equal to Sci-Tech

    Institute of Scientific and Technical Information of China (English)

    Xingmin Li

    2003-01-01

    @@ The terms "science" (Hanyu Pinyin: Kēxué) and"technology" (Jìshù), in western languages, are usu-ally used separately with different meanings or to-gether as "science and technology". However, theyare often mentioned as "Kēxué Jìshù", or even abbre-viated as "sci-tech (Kējì)" in China (It is used in asimilar way in Japan).

  5. A Platform Across the Valley of Death: Tech Transition via Open Enterprise Information System Development

    OpenAIRE

    2014-01-01

    Approved for public release; distribution is unlimted. Achieving “Tech Transfer”, i.e. “an invention usefully adopted,” is difficult, particularly within the Defense Enterprise. The Defense acquisition system is designed to transition technology through a long serial process ill suited for Information Technology (IT). However, there is a successful commercial practice for transitioning IT called “Product Line Architecture” (PLA). PLA optimizes a specified open standard technical framework ...

  6. Challenges to achievement of metal sustainability in our high-tech society.

    Science.gov (United States)

    Izatt, Reed M; Izatt, Steven R; Bruening, Ronald L; Izatt, Neil E; Moyer, Bruce A

    2014-04-21

    Achievement of sustainability in metal life cycles from mining of virgin ore to consumer and industrial devices to end-of-life products requires greatly increased recycling rates and improved processing of metals using conventional and green chemistry technologies. Electronic and other high-tech products containing precious, toxic, and specialty metals usually have short lifetimes and low recycling rates. Products containing these metals generally are incinerated, discarded as waste in landfills, or dismantled in informal recycling using crude and environmentally irresponsible procedures. Low recycling rates of metals coupled with increasing demand for high-tech products containing them necessitate increased mining with attendant environmental, health, energy, water, and carbon-footprint consequences. In this tutorial review, challenges to achieving metal sustainability, including projected use of urban mining, in present high-tech society are presented; health, environmental, and economic incentives for various government, industry, and public stakeholders to improve metal sustainability are discussed; a case for technical improvements, including use of molecular recognition, in selective metal separation technology, especially for metal recovery from dilute feed stocks is given; and global consequences of continuing on the present path are examined.

  7. Mineral resources of high-tech metals in Russia: State of the art and outlook

    Science.gov (United States)

    Bortnikov, N. S.; Volkov, A. V.; Galyamov, A. L.; Vikent'ev, I. V.; Aristov, V. V.; Lalomov, A. V.; Murashov, K. Yu.

    2016-03-01

    Seven main ore-forming systems—porphyry and epithermal; orogenic related to granitic intrusions; magmatic ultramafic; volcanic-hosted massive sulfide and volcanic-sedimentary; sedimentary basins; related to alkaline magmatic activity; and placers and weathering mantles—are sources of high-tech critical metals. The following promising types of ore deposits containing high-tech critical metals as by-products are recognized: Cu-Mo porphyry, Fe-Cu-Au and Pb-Zn skarn, base-metal epithermal, volcanic-hosted massive sulfide, base-metal stratiform, various tin deposits, and placers containing rare metals including REE. The mineral resources of critical metals in Russia are compared with those known in other countries. The contents of high-tech critical metals in ores of some noble-metal deposits of the Russian Northeast are reported. It is shown that the subsurface of Russia possesses considerable mineral resource potential for hightech critical metals, which allows new enterprises to be created or production of operating enterprises to increase.

  8. Pricing and inventory policies for Hi-tech products under replacement warranty

    Science.gov (United States)

    Tsao, Yu-Chung; Teng, Wei-Guang; Chen, Ruey-Shii; Chou, Wang-Ying

    2014-06-01

    Companies, especially in the Hi-tech (high-technology) industry (such as computer, communication and consumer electronic products), often provide a replacement warranty period for purchased items. In reality, simultaneously determining the price and inventory decisions under warranty policy is an important issue. The objective of this paper is to develop a joint pricing and inventory model for Hi-tech products under replacement warranty policy. In the first model, we consider a Hi-tech product feature in which the selling price is declining in a trend. We determine the optimal inventory level for each period and retail price for the first period while maximising the total profit. In the second model, we further determine the optimal retail price and inventory level for each period in the dynamic demand market. This study develops solution approaches to solve the problems described above. Numerical analysis discusses the influence of system parameters on the company's decisions and behaviours. The results of this study could serve as a reference for business managers or administrators.

  9. DIFFUSION OF INNOVATION PROCESSES IN HIGH-TECH PRODUCTION OF MEDICAL INDUSTRY OF RUSSIA

    Directory of Open Access Journals (Sweden)

    Дарья Витальевна Костина

    2013-10-01

    Full Text Available The concept of diffusion of the innovation process is explained, the theoretical aspects and some scientific works of Schumpeter I., Zavlin P.N., Kazantsev L.K., Mindeli L.E., T. Hegerstrand, E.Rodzhersa are reviewed. The possibilities of the Russian market, the diffusion of innovation processes in the high-tech medical industry of Russia are cosidered. Based on this analysis the author summarizes and assesses the potential and importance of the diffusion of innovative processes for the production of high-tech medical products in the Russian market .At the end of the article it is concluded that the spread of innovations in the medical industry is a necessary component of economic growth not only of this industry, but the economy as a whole. In fact the transition of economy to production of high-tech products is accompanied by a sharp reduction of the level of material and energy consumption, increase in productivity and improvement of competitiveness of the economy.DOI: http://dx.doi.org/10.12731/2218-7405-2013-9-42

  10. The body participating:

    DEFF Research Database (Denmark)

    Pallesen, Hanne; Lund, Lone Blak; Jensen, Marianne

    2017-01-01

    ABSTRACT Background: The literature on participation in rehabilitation by those with the most severe acquired brain injury is very sparse. Objectives: The aim of this study was to explore how physiotherapists promote the participation of patients with severe brain injury in therapeutic and daily-...... and low level of consciousness in terms of their participation and functioning in everyday life.......-based analyses. The results were theoretically stated and supported. Results: In an effort to achieve patient participation, the following four themes seemed to be significant: 1) consciously encountering the patient in the moment, 2) the employment of concepts surrounding the interaction between body...

  11. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2011-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  12. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2010-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  13. The High-Tech Face of e-Health

    CERN Document Server

    Shiers, Jamie D

    2014-01-01

    This chapter focuses on the current and potential use of e-Infrastructures in the domain of eHealth. It starts by identifying a small number of specific Use Cases and then addresses how these can be optimized—or possibly revolutionized—by the use of state-of-the-art distributing computing infrastructures (DCIs). Specific topics that are addressed include “long-term” data preservation (for the duration of a patient’s life as well as (far) beyond for collective-oriented studies), federation of heterogeneous data sources, provision of redundant and highly accessible data storage and federated identity management. The work draws heavily on the author’s experience in distributed computing infrastructures to address the challenges of the Large Hadron Collider at CERN, together with participation in generic e-Infrastructure projects, such as the EGEE project services and EGI. It also benefits from experience in hadron-therapy oriented projects with which CERN has synergies both as an accelerator laborato...

  14. Regional development strategy of high-tech industry: The case of Vojvodina

    Directory of Open Access Journals (Sweden)

    Adžić Sofija

    2006-01-01

    Full Text Available The initial thesis in the present work is that the solution of the problem of improving the competiveness of the economy of Vojvodina indispensably should open the room for the development of high-tech industries, in the first line on the basis of dynamic entrepreneurship and development of small and medium enterprises (SMEs. Emphasis in the research is on the analysis of the problem of inappropriate institutional order as a factor blocking innovative entrepreneurial conduct, technological development and economic valorization of high technologies, efficient socio-economic coordination of individual development initiatives and larger orientation of financial capital to risky investments in new industries. In this context, the most important limiting factors of development and economic valorization of high technologies in Vojvodina are defined as: (1 absence of socio-economic motivation for innovative behavior and manufacturing entrepreneurship, (2 low availability of skilled and internationally competent labour, (3 poor quality of regional, subregional and local STIEOT infrastructure, (4 orientation of regional financial infrastructure to credit imports and population and (5 low efficiency of regional, sub regional and local administrative and public services in eliminating above problems. In the light of those observations the operationalization of the concrete contents of development strategy for high-tech industries in Vojvodina is defined as a measure of ability to include regional, subregional and local institutions and public services to find how to solve the following problems: 1. providing conditions for internationally competent training of entrepreneurs, managers and expert teams in the function of acquiring necessary knowledge for the implementation of modern technological, managerial and organizational solutions needed for the foundation and dynamic development of high-tech enterprises, 2. provision of technical and economic support

  15. Sense of participation

    NARCIS (Netherlands)

    Bohorques Montemayor, L.; Nevejan, C.I.M.; Brazier, F.M.

    2013-01-01

    This paper explores the sense of participation of a spatially distributed individual—in the intersections of physical and mediated networks. This sense is fundamental to an individuals’ experience as a participant in systems designed to this purpose including today’s social media and new media gener

  16. Outdoor recreation participation trends

    Science.gov (United States)

    H. Ken Cordell; Barbara L. McDonald; R. Jeff Teasley; John C. Bergstrom; Jack Martin; Jim Bason; Vernon R. Leeworthy

    1999-01-01

    As part of the national assessment of outdoor recreation trends, the authors have taken a look at participation patterns and levels of participation across activities and across segments of our society. The primary source of data is the National Survey on Recreation and the Environment (NSRE). The NSRE is the latest in the continuing series of National Recreation...

  17. Sense of participation

    NARCIS (Netherlands)

    Bohorques Montemayor, L.; Nevejan, C.I.M.; Brazier, F.M.

    2013-01-01

    This paper explores the sense of participation of a spatially distributed individual—in the intersections of physical and mediated networks. This sense is fundamental to an individuals’ experience as a participant in systems designed to this purpose including today’s social media and new media

  18. Participation beyond observation

    DEFF Research Database (Denmark)

    Chimirri, Niklas Alexander

    , however, the researchers typically uphold the notion that all they methodically engage in is participant observation. The paper argues that important aspects of children’s living and understanding may be lost when considering them mere objects of one’s visual and verbal research practices. First I delve...... on investigating children’s perspectives through participant observation, but also ontological and political ones....

  19. Depression and Political Participation*

    Science.gov (United States)

    Ojeda, Christopher

    2015-01-01

    In this paper, I propose that depression is a political phenomenon insofar as it has political sources and consequences. I then investigate one aspect of this argument—whether depression reduces participation. I hypothesize that individuals with depression lack the motivation and physical capacity to vote and engage in other forms of political participation due to somatic problems and feelings of hopelessness and apathy. Moreover, I examine how depression in adolescence can have downstream consequences for participation in young adulthood. The analyses, using both cross-sectional and longitudinal data, show that voter turnout and other forms of participation decrease as the severity of depressed mood increases. These findings are discussed in light of disability rights and potential efforts to boost participation among this group. PMID:26924857

  20. Depression and Political Participation.

    Science.gov (United States)

    Ojeda, Christopher

    2015-11-01

    In this paper, I propose that depression is a political phenomenon insofar as it has political sources and consequences. I then investigate one aspect of this argument-whether depression reduces participation. I hypothesize that individuals with depression lack the motivation and physical capacity to vote and engage in other forms of political participation due to somatic problems and feelings of hopelessness and apathy. Moreover, I examine how depression in adolescence can have downstream consequences for participation in young adulthood. The analyses, using both cross-sectional and longitudinal data, show that voter turnout and other forms of participation decrease as the severity of depressed mood increases. These findings are discussed in light of disability rights and potential efforts to boost participation among this group.