WorldWideScience

Sample records for tbc systems fabricated

  1. Damage evolution of TBC system under in-phase thermo-mechanical tests

    International Nuclear Information System (INIS)

    Kitazawa, R.; Tanaka, M.; Kagawa, Y.; Liu, Y.F.

    2010-01-01

    In-phase thermo-mechanical tests (TMF) of EB-PVD Y 2 O 3 -ZrO 2 thermal barrier coating (TBC) system (8 wt% Y 2 O 3 -ZrO 2 /CoNiCrAlY/IN-738 substrate) were done under a through-the-thick-direction thermal gradient from TBC surface temperature at 1150 deg. C to substrate temperature at 1000 deg. C. Deformation and failure behaviors of the TBC system were observed at the macroscopic and microscopic scales and damage evolution of the system under in-phase thermo-mechanical test was discussed. Special attention was paid to TBC layer cracking, thermally grown oxide (TGO) layer formation and void formation in bond coat and substrate. Effect of TMF conditions on the damage evolution behaviors was also discussed.

  2. Damage evolution of TBC system under in-phase thermo-mechanical tests

    Energy Technology Data Exchange (ETDEWEB)

    Kitazawa, R.; Tanaka, M.; Kagawa, Y. [Research Center for Advanced Science and Technology, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904 (Japan); Liu, Y.F., E-mail: yfliu@hyper.rcast.u-tokyo.ac.jp [Research Center for Advanced Science and Technology, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904 (Japan)

    2010-10-15

    In-phase thermo-mechanical tests (TMF) of EB-PVD Y{sub 2}O{sub 3}-ZrO{sub 2} thermal barrier coating (TBC) system (8 wt% Y{sub 2}O{sub 3}-ZrO{sub 2}/CoNiCrAlY/IN-738 substrate) were done under a through-the-thick-direction thermal gradient from TBC surface temperature at 1150 deg. C to substrate temperature at 1000 deg. C. Deformation and failure behaviors of the TBC system were observed at the macroscopic and microscopic scales and damage evolution of the system under in-phase thermo-mechanical test was discussed. Special attention was paid to TBC layer cracking, thermally grown oxide (TGO) layer formation and void formation in bond coat and substrate. Effect of TMF conditions on the damage evolution behaviors was also discussed.

  3. Degradation of TBC Systems in Environments Relevant to Advanced Gas Turbines for IGCC Systems

    Energy Technology Data Exchange (ETDEWEB)

    Gleeson, Brian [Univ. of Pittsburgh, PA (United States)

    2014-09-30

    Air plasma sprayed (APS) thermal barrier coatings (TBCs) are used to provide thermal insulation for the hottest components in gas turbines. Zirconia stabilized with 7wt% yttria (7YSZ) is the most common ceramic top coat used for turbine blades. The 7YSZ coating can be degraded from the buildup of fly-ash deposits created in the power-generation process. Fly ash from an integrated gasification combined cycle (IGCC) system can result from coal-based syngas. TBCs are also exposed to harsh gas environments containing CO2, SO2, and steam. Degradation from the combined effects of fly ash and harsh gas atmospheres has the potential to severely limit TBC lifetimes. The main objective of this study was to use lab-scale testing to systematically elucidate the interplay between prototypical deposit chemistries (i.e., ash and its constituents, K2SO4, and FeS) and environmental oxidants (i.e., O2, H2O and CO2) on the degradation behavior of advanced TBC systems. Several mechanisms of early TBC failure were identified, as were the specific fly-ash constituents responsible for degradation. The reactivity of MCrAlY bondcoats used in TBC systems was also investigated. The specific roles of oxide and sulfate components were assessed, together with the complex interplay between gas composition, deposit chemistry and alloy reactivity. Bondcoat composition design strategies to mitigate corrosion were established, particularly with regard to controlling phase constitution and the amount of reactive elements the bondcoat contains in order to achieve optimal corrosion resistance.

  4. Influence of material and testing parameters on the lifetime of TBC systems with MCrAlY and NiPtAl bondcoats

    Energy Technology Data Exchange (ETDEWEB)

    Song, Peng

    2012-08-31

    The oxidation behavior of the bond coat is an important factor determining the lifetime of thermal barrier coatings (TBC) in the advanced gas turbine components. In the present work, the effect of various testing parameters, such as hot/cold dwell time, heating/cooling rate, atmosphere composition on the bondcoat oxidation and associated TBC lifetime has been investigated. The range of coating systems included Electron Beam - Physical Vapor Deposited (EB-PVD) and Air Plasma Sprayed (APS) TBC's with MCrAlY (M = Ni, Co) and NiPtAl-bondcoats of various compositions. The effect of the testing parameters strongly depended on the type and properties of the studied system. The lifetime of EB-PVD TBC systems with conventional MCrAlY and NiPtAl bondcoats forming uniform, flat alumina scales was found to be limited by critical scale thickness, upon which a rapid crack propagation at the scale/bondcoat interface results in macroscopic failure. The lifetime of such systems was found to be affected by factors, which influence the scale growth rate and adherence (in particular by oxygen partial pressure (pO{sub 2}) and water vapor content in the test gas in the case of MCrAlY), whereas the temperature cyclic frequency showed no significant effect. NiPtAl bondcoats showed a superior behavior than the conventional MCrAlY-bondcoats due to slower scale growth rate and better scale adherence. For EB-PVD TBC systems with Zr-doped MCrAlYbondcoats the lifetime is mainly determined by the crack growth rate in the inhomogeneous inwardly growing oxide scales, whereas the lifetime is not dependent on the pO{sub 2} but rather on the cyclic frequency. For APS TBC systems the bondcoat oxidation is only one of several factors determining the ceramic topcoat lifetime. Therefore the oxide scale adherence is of less importance for lifetime of APS TBCs as compared to EBPVD TBCs. For the former systems, the cracks initiated at the convex asperities of the rough oxide scale / bondcoat interface

  5. The lustering of TBC-2

    Energy Technology Data Exchange (ETDEWEB)

    Diver, R.B.; Jones, S.; Robb, S.; Mahoney, A.R.

    1995-05-01

    Two test bed concentrators (TBCs) were designed to provide high-performance test beds for advanced solar receivers and converters. However, the second-surface silvered-glass mirror facets on the TBCs, which were originally manufactured by the Jet Propulsion Laboratory, have experienced severe silver corrosion. To restore reflectance, TBC-2 was refurbished with a lustering technique developed at Sandia National Laboratories. In the lustering technique, second-surface silvered thin-glass mirrors were applied over the corroded facets, thereby increasing the dish reflectivity and raising the available power of TBC-2 from approximately 70 to 78 kW{sub t}. Degradation of the original optical accuracy of the TBC facets was determined to be minimal. Lustering was chosen over facet replacement because of the lower cost, the anticipated improvement in corrosion resistance, and the shorter project duration. This report includes background information, details of the lustering process, and test results from TBC-2 characterization, both before and after lustering.

  6. PVD TBC experience on GE aircraft engines

    Science.gov (United States)

    Maricocchi, Antonio; Bartz, Andi; Wortman, David

    1995-01-01

    The higher performance levels of modern gas turbine engines present significant challenges in the reliability of materials in the turbine. The increased engine temperatures required to achieve the higher performance levels reduce the strength of the materials used in the turbine sections of the engine. Various forms of thermal barrier coatings (TBC's) have been used for many years to increase the reliability of gas turbine engine components. Recent experience with the physical vapor deposition (PVD) process using ceramic material has demonstrated success in extending the service life of turbine blades and nozzles. Engine test results of turbine components with a 125 micron (0.005 in) PVD TBC have demonstrated component operating temperatures of 56-83 C (100-150 F) lower than non-PVD TBC components. Engine testing has also revealed the TBC is susceptible to high angle particle impact damage. Sand particles and other engine debris impact the TBC surface at the leading edge of airfoils and fracture the PVD columns. As the impacting continues, the TBC erodes away in local areas. Analysis of the eroded areas has shown a slight increase in temperature over a fully coated area, however a significant temperature reduction was realized over an airfoil without TBC.

  7. Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle.

    Science.gov (United States)

    Treebak, Jonas T; Pehmøller, Christian; Kristensen, Jonas M; Kjøbsted, Rasmus; Birk, Jesper B; Schjerling, Peter; Richter, Erik A; Goodyear, Laurie J; Wojtaszewski, Jørgen F P

    2014-01-15

    We investigated the phosphorylation signatures of two Rab-GTPase activating proteins TBC1D1 and TBC1D4 in human skeletal muscle in response to physical exercise and physiological insulin levels induced by a carbohydrate rich meal using a paired experimental design. Eight healthy male volunteers exercised in the fasted or fed state and muscle biopsies were taken before and immediately after exercise. We identified TBC1D1/4 phospho-sites that (1) did not respond to exercise or postprandial increase in insulin (TBC1D4: S666), (2) responded to insulin only (TBC1D4: S318), (3) responded to exercise only (TBC1D1: S237, S660, S700; TBC1D4: S588, S751), and (4) responded to both insulin and exercise (TBC1D1: T596; TBC1D4: S341, T642, S704). In the insulin-stimulated leg, Akt phosphorylation of both T308 and S473 correlated significantly with multiple sites on both TBC1D1 (T596) and TBC1D4 (S318, S341, S704). Interestingly, in the exercised leg in the fasted state TBC1D1 phosphorylation (S237, T596) correlated significantly with the activity of the α2/β2/γ3 AMPK trimer, whereas TBC1D4 phosphorylation (S341, S704) correlated with the activity of the α2/β2/γ1 AMPK trimer. Our data show differential phosphorylation of TBC1D1 and TBC1D4 in response to physiological stimuli in human skeletal muscle and support the idea that Akt and AMPK are upstream kinases. TBC1D1 phosphorylation signatures were comparable between in vitro contracted mouse skeletal muscle and exercised human muscle, and we show that AMPK regulated phosphorylation of these sites in mouse muscle. Contraction and exercise elicited a different phosphorylation pattern of TBC1D4 in mouse compared with human muscle, and although different circumstances in our experimental setup may contribute to this difference, the observation exemplifies that transferring findings between species is problematic.

  8. TBC1D24 genotype–phenotype correlation

    Science.gov (United States)

    Balestrini, Simona; Milh, Mathieu; Castiglioni, Claudia; Lüthy, Kevin; Finelli, Mattea J.; Verstreken, Patrik; Cardon, Aaron; Stražišar, Barbara Gnidovec; Holder, J. Lloyd; Lesca, Gaetan; Mancardi, Maria M.; Poulat, Anne L.; Repetto, Gabriela M.; Banka, Siddharth; Bilo, Leonilda; Birkeland, Laura E.; Bosch, Friedrich; Brockmann, Knut; Cross, J. Helen; Doummar, Diane; Félix, Temis M.; Giuliano, Fabienne; Hori, Mutsuki; Hüning, Irina; Kayserili, Hulia; Kini, Usha; Lees, Melissa M.; Meenakshi, Girish; Mewasingh, Leena; Pagnamenta, Alistair T.; Peluso, Silvio; Mey, Antje; Rice, Gregory M.; Rosenfeld, Jill A.; Taylor, Jenny C.; Troester, Matthew M.; Stanley, Christine M.; Ville, Dorothee; Walkiewicz, Magdalena; Falace, Antonio; Fassio, Anna; Lemke, Johannes R.; Biskup, Saskia; Tardif, Jessica; Ajeawung, Norbert F.; Tolun, Aslihan; Corbett, Mark; Gecz, Jozef; Afawi, Zaid; Howell, Katherine B.; Oliver, Karen L.; Berkovic, Samuel F.; Scheffer, Ingrid E.; de Falco, Fabrizio A.; Oliver, Peter L.; Striano, Pasquale; Zara, Federico

    2016-01-01

    Objective: To evaluate the phenotypic spectrum associated with mutations in TBC1D24. Methods: We acquired new clinical, EEG, and neuroimaging data of 11 previously unreported and 37 published patients. TBC1D24 mutations, identified through various sequencing methods, can be found online (http://lovd.nl/TBC1D24). Results: Forty-eight patients were included (28 men, 20 women, average age 21 years) from 30 independent families. Eighteen patients (38%) had myoclonic epilepsies. The other patients carried diagnoses of focal (25%), multifocal (2%), generalized (4%), and unclassified epilepsy (6%), and early-onset epileptic encephalopathy (25%). Most patients had drug-resistant epilepsy. We detail EEG, neuroimaging, developmental, and cognitive features, treatment responsiveness, and physical examination. In silico evaluation revealed 7 different highly conserved motifs, with the most common pathogenic mutation located in the first. Neuronal outgrowth assays showed that some TBC1D24 mutations, associated with the most severe TBC1D24-associated disorders, are not necessarily the most disruptive to this gene function. Conclusions: TBC1D24-related epilepsy syndromes show marked phenotypic pleiotropy, with multisystem involvement and severity spectrum ranging from isolated deafness (not studied here), benign myoclonic epilepsy restricted to childhood with complete seizure control and normal intellect, to early-onset epileptic encephalopathy with severe developmental delay and early death. There is no distinct correlation with mutation type or location yet, but patterns are emerging. Given the phenotypic breadth observed, TBC1D24 mutation screening is indicated in a wide variety of epilepsies. A TBC1D24 consortium was formed to develop further research on this gene and its associated phenotypes. PMID:27281533

  9. FEM simulation of TBC failure in a model system

    Energy Technology Data Exchange (ETDEWEB)

    Seiler, P; Baeker, M; Roesier, J [Institut fuer Werkstoffe (IfW), Technische Universitaet Braunschweig (Germany); Beck, T; Schweda, M, E-mail: p.seiler@tu-bs.d [Institut fuer Energieforschung/ Werkstoffstruktur und -Eigenschaften (IEF 2), Forschungszentrum Juelich (Germany)

    2010-07-01

    In order to study the behavior of the complex failure mechanisms in thermal barrier coatings on turbine blades, a simplified model system is used to reduce the number of system parameters. The artificial system consists of a bond-coat material (fast creeping Fecralloy or slow creeping MA956) as the substrate with a Y{sub 2}O{sub 3} partially stabilized plasma sprayed zircon oxide TBC on top and a TGO between the two layers. A 2-dimensional FEM simulation was developed to calculate the growth stress inside the simplified coating system. The simulation permits the study of failure mechanisms by identifying compression and tension areas which are established by the growth of the oxide layer. This provides an insight into the possible crack paths in the coating and it allows to draw conclusions for optimizing real thermal barrier coating systems.

  10. Lifetime-determining spalling mechanisms of NiCoCrAlRe/EB-PVD zirconia TBC systems

    Energy Technology Data Exchange (ETDEWEB)

    Fritscher, K.; Schulz, U. [DLR - German Aerospace Center, Institute of Materials Research, 51170 Cologne (Germany); Leyens, C. [Technical University of Brandenburg (BTU) Cottbus, Chair of Physical Metallurgy and Materials Technology, 03046 Cottbus (Germany)

    2007-09-15

    The mechanisms that control the lifetime of thermal barrier coating (TBC) systems have been traced by two particular overlay bondcoats serving as model systems: superalloy pins (IN100, CMSX-4) with two alternative NiCoCrAlRE (RE: Hf, Y) bond coat compositions (i) NiCoCrAlY without and (ii) with co-dopants of silicon and hafnium. On top an electron-beam physical-vapor deposited (EB-PVD) yttria partially stabilized zirconia (YPSZ) TBC commonly mixed with 2 wt.% hafnia, or, rarely with 10 wt.%, was applied. The test pins were thermo-cycled at 1100 and 1150 C until failure. Identical lifetimes in cyclic tests on YPSZ TBCs with 2 (relatively high sintering rate) and 10 wt.% hafnia (relatively low sintering rate) preclude an effect of diffusion mechanisms of the YPSZ TBC on lifetime. The fit of lifetimes and test temperatures to Arrhenius-type relationships gives activation energies for failure. These energies agree with the activation energies for anion and cation diffusion in alumina for the respective bondcoat variant: (i) for the NiCoCrAlY/TBC system for O{sup 2-} diffusion in alumina, (ii) for the NiCoCrAlYSiHf/TBC system for Al{sup 3+} diffusion in alumina. SEM and EDS investigations of the thermally grown oxides (TGOs) confirm the mechanisms responsible for TBC failure as indicated by activation energies. Two categories of failure can be distinguished: (i) NiCoCrAlY coatings fail by an ''adhesive mode of failure'' along smooth bond coat/TGO interfaces driven by a critical TGO thickness. (ii) NiCoCrAlYSiHf coatings fail later and more reluctantly by a ''cohesive'' crack mode via de-cohesion at the TGO/TBC interface. In the latter case a quasi-integrity of the crack-affected TGO is lengthily maintained up to failure by a crack-pinning mechanism which runs via Al{sup 3+} supply from the bondcoat. (Abstract Copyright [2007], Wiley Periodicals, Inc.) [German] Die Mechanismen, welche die Lebensdauer von Waermedaemmschichtsystemen

  11. Exercise increases TBC1D1 phosphorylation in human skeletal muscle

    Science.gov (United States)

    Jessen, Niels; An, Ding; Lihn, Aina S.; Nygren, Jonas; Hirshman, Michael F.; Thorell, Anders

    2011-01-01

    Exercise and weight loss are cornerstones in the treatment and prevention of type 2 diabetes, and both interventions function to increase insulin sensitivity and glucose uptake into skeletal muscle. Studies in rodents demonstrate that the underlying mechanism for glucose uptake in muscle involves site-specific phosphorylation of the Rab-GTPase-activating proteins AS160 (TBC1D4) and TBC1D1. Multiple kinases, including Akt and AMPK, phosphorylate TBC1D1 and AS160 on distinct residues, regulating their activity and allowing for GLUT4 translocation. In contrast to extensive rodent-based studies, the regulation of AS160 and TBC1D1 in human skeletal muscle is not well understood. In this study, we determined the effects of dietary intervention and a single bout of exercise on TBC1D1 and AS160 site-specific phosphorylation in human skeletal muscle. Ten obese (BMI 33.4 ± 2.4, M-value 4.3 ± 0.5) subjects were studied at baseline and after a 2-wk dietary intervention. Muscle biopsies were obtained from the subjects in the resting (basal) state and immediately following a 30-min exercise bout (70% V̇o2 max). Muscle lysates were analyzed for AMPK activity and Akt phosphorylation and for TBC1D1 and AS160 phosphorylation on known or putative AMPK and Akt sites as follows: AS160 Ser711 (AMPK), TBC1D1 Ser231 (AMPK), TBC1D1 Ser660 (AMPK), TBC1D1 Ser700 (AMPK), and TBC1D1 Thr590 (Akt). The diet intervention that consisted of a major shift in the macronutrient composition resulted in a 4.2 ± 0.4 kg weight loss (P < 0.001) and a significant increase in insulin sensitivity (M value 5.6 ± 0.6), but surprisingly, there was no effect on expression or phosphorylation of any of the muscle-signaling proteins. Exercise increased muscle AMPKα2 activity but did not increase Akt phosphorylation. Exercise increased phosphorylation on AS160 Ser711, TBC1D1 Ser231, and TBC1D1 Ser660 but had no effect on TBC1D1 Ser700. Exercise did not increase TBC1D1 Thr590 phosphorylation or TBC1D1/AS160 PAS

  12. 3D-simulation of residual stresses in TBC plasma sprayed coating

    International Nuclear Information System (INIS)

    Kundas, S.; Kashko, T.; Hurevich, V.E.; Lugscheider, E.; Hayn, G. von; Ilyuschenko, A.

    2001-01-01

    Thermal barrier coatings (TBC) are used in gas turbine technology in order to protect against overheating of the nickel alloy turbine blades. This coatings allows to increase turbine inlet temperatures and improve their efficiency. Plasma spraying processes are widely used since several years in thermal barrier coating technology. Although the plasma spraying process of TBC's is largely successful, a fundamental understanding of the process parameters influencing the TBC microstructure and mechanical properties is necessary. But this investigation has received much less attention so they could lead to considerable advances in performance of plasma sprayed thermal barrier coatings. The main reason of this mate is difficulties in experimental investigation of high temperature and high velocity process. One of the most effective ways to accelerate the process optimization is the application of computer simulation for the modeling of plasma spraying. This enables the achievement of a maximum of information about the investigated process by carrying out a minimum number of experiments. The main problem of plasma spray TBC coatings is crack information during the deposition process and coating cooling. The reasons for this are quenched and residual stresses in the coating-substrate system, and peculiarities of TBC coating properties. The problem of deposition and solidification of plasma sprayed coatings have received little attention to date and remains one of the unintelligible parts of process. A fundamental understanding of heat transfer in the coating-substrate system and particles deformation processes are, however, critical for the prediction of the microstructural characteristics of the deposited coatings, the understanding of the mechanisms involved in formation of thermal stresses and defects (cracks, debonding etc.). (author)

  13. TBC2target: A Resource of Predicted Target Genes of Tea Bioactive Compounds

    Directory of Open Access Journals (Sweden)

    Shihua Zhang

    2018-02-01

    Full Text Available Tea is one of the most popular non-alcoholic beverages consumed worldwide. Numerous bioactive constituents of tea were confirmed to possess healthy benefits via the mechanisms of regulating gene expressions or protein activities. However, a complete interacting profile between tea bioactive compounds (TBCs and their target genes is lacking, which put an obstacle in the study of healthy function of tea. To fill this gap, we developed a database of target genes of TBCs (TBC2target, http://camellia.ahau.edu.cn/TBC2target based on a pharmacophore mapping approach. In TBC2target, 6,226 interactions between 240 TBCs and 673 target genes were documented. TBC2target contains detailed information about each interacting entry, such as TBC, CAS number, PubChem CID, source of compound (e.g., green, black, compound type, target gene(s of TBC, gene symbol, gene ID, ENSEMBL ID, PDB ID, TBC bioactivity and the reference. Using the TBC-target associations, we constructed a bipartite network and provided users the global network and local sub-network visualization and topological analyses. The entire database is free for online browsing, searching and downloading. In addition, TBC2target provides a BLAST search function to facilitate use of the database. The particular strengths of TBC2target are the inclusion of the comprehensive TBC-target interactions, and the capacity to visualize and analyze the interacting networks, which may help uncovering the beneficial effects of tea on human health as a central resource in tea health community.

  14. TBC2target: A Resource of Predicted Target Genes of Tea Bioactive Compounds.

    Science.gov (United States)

    Zhang, Shihua; Zhang, Liang; Wang, Yijun; Yang, Jian; Liao, Mingzhi; Bi, Shoudong; Xie, Zhongwen; Ho, Chi-Tang; Wan, Xiaochun

    2018-01-01

    Tea is one of the most popular non-alcoholic beverages consumed worldwide. Numerous bioactive constituents of tea were confirmed to possess healthy benefits via the mechanisms of regulating gene expressions or protein activities. However, a complete interacting profile between tea bioactive compounds (TBCs) and their target genes is lacking, which put an obstacle in the study of healthy function of tea. To fill this gap, we developed a database of target genes of TBCs (TBC2target, http://camellia.ahau.edu.cn/TBC2target) based on a pharmacophore mapping approach. In TBC2target, 6,226 interactions between 240 TBCs and 673 target genes were documented. TBC2target contains detailed information about each interacting entry, such as TBC, CAS number, PubChem CID, source of compound (e.g., green, black), compound type, target gene(s) of TBC, gene symbol, gene ID, ENSEMBL ID, PDB ID, TBC bioactivity and the reference. Using the TBC-target associations, we constructed a bipartite network and provided users the global network and local sub-network visualization and topological analyses. The entire database is free for online browsing, searching and downloading. In addition, TBC2target provides a BLAST search function to facilitate use of the database. The particular strengths of TBC2target are the inclusion of the comprehensive TBC-target interactions, and the capacity to visualize and analyze the interacting networks, which may help uncovering the beneficial effects of tea on human health as a central resource in tea health community.

  15. Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.

    Science.gov (United States)

    Vichaiwong, Kanokwan; Purohit, Suneet; An, Ding; Toyoda, Taro; Jessen, Niels; Hirshman, Michael F; Goodyear, Laurie J

    2010-10-15

    TBC1D1 (tre-2/USP6, BUB2, cdc16 domain family member 1) is a Rab-GAP (GTPase-activating protein) that is highly expressed in skeletal muscle, but little is known about TBC1D1 regulation and function. We studied TBC1D1 phosphorylation on three predicted AMPK (AMP-activated protein kinase) phosphorylation sites (Ser231, Ser660 and Ser700) and one predicted Akt phosphorylation site (Thr590) in control mice, AMPKα2 inactive transgenic mice (AMPKα2i TG) and Akt2-knockout mice (Akt2 KO). Muscle contraction significantly increased TBC1D1 phosphorylation on Ser231 and Ser660, tended to increase Ser700 phosphorylation, but had no effect on Thr590. AICAR (5-aminoimidazole-4-carboxyamide ribonucleoside) also increased phosphorylation on Ser231, Ser660 and Ser700, but not Thr590, whereas insulin only increased Thr590 phosphorylation. Basal and contraction-stimulated TBC1D1 Ser231, Ser660 and Ser700 phosphorylation were greatly reduced in AMPKα2i TG mice, although contraction still elicited a small increase in phosphorylation. Akt2 KO mice had blunted insulin-stimulated TBC1D1 Thr590 phosphorylation. Contraction-stimulated TBC1D1 Ser231 and Ser660 phosphorylation were normal in high-fat-fed mice. Glucose uptake in vivo was significantly decreased in tibialis anterior muscles overexpressing TBC1D1 mutated on four predicted AMPK phosphorylation sites. In conclusion, contraction causes site-specific phosphorylation of TBC1D1 in skeletal muscle, and TBC1D1 phosphorylation on AMPK sites regulates contraction-stimulated glucose uptake. AMPK and Akt regulate TBC1D1 phosphorylation, but there must be additional upstream kinases that mediate TBC1D1 phosphorylation in skeletal muscle.

  16. Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 in human skeletal muscle

    DEFF Research Database (Denmark)

    Treebak, Jonas Thue; Pehmøller, Christian; Kristensen, Jonas Møller

    2014-01-01

    We investigated the phosphorylation signatures of two Rab GTPase activating proteins TBC1D1 and TBC1D4 in human skeletal muscle in response to physical exercise and physiological insulin levels induced by a carbohydrate rich meal using a paired experimental design. Eight healthy male volunteers e...

  17. Degradation of TBC Systems in Environments Relevant to Advanced Gas Turbines for IGCC Systems

    Science.gov (United States)

    Bohna, Nathaniel Allan

    Plasma sprayed (PS) thermal barrier coatings (TBCs) are used to provide thermal insulation for the hottest components in gas turbines. Zirconia stabilized with 7wt% yttria (7YSZ) is the most common ceramic top coat used for turbine blades. The 7YSZ coating can be degraded by the buildup of fly-ash deposits which can arise from the fuel source (coal/biomass) used in the combustion process in gas turbines. Fly-ash from the integrated gasification combined cycle (IGCC) process can result from coal-based syngas and also from ambient air which passes through the system. TBCs are also exposed to harsh gas environments containing CO2, SO2, and steam. As presented in this thesis, degradation from the combined effects of fly-ash and harsh gas atmosphere can severely limit TBC lifetimes. It is well established that degradation at very high temperatures (≥1250°C) from deposits consisting of the oxides CaO-MgO-Al2O3-SiO 2 results from extensive liquid silicate infiltration into the porous top coat of the YSZ. This infiltration causes early failure resulting from chemical and/or mechanical damage to the ceramic layer. Damage resulting from liquid infiltration, however, is not typically considered at relatively lower temperatures around 1100°C because liquid silicates would not be expected to form from the oxides in the deposit. A key focus of this study is to assess the mode and extent of TBC degradation at 1100°C in cases when some amount of liquid forms owing to the presence of K2SO4 as a minor ash constituent. Two types of liquid infiltrations are observed depending on the principal oxide (i.e., CaO or SiO2) in the deposit. The degradation is primarily the result of mechanical damage, which results from infiltration caused by the interaction of liquid K2SO4 with either the CaO or SiO2. The TBCs used in this work are representative of commonly used coatings used in the hottest sections of land-based gas turbines. The specimens consist of 7YSZ top coats deposited on

  18. Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is regulated by protein palmitoylation

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Chen; Lange, Jeffrey J.; Samovski, Dmitri [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Su, Xiong [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States); Liu, Jialiu [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Sundaresan, Sinju [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States); Stahl, Philip D., E-mail: pstahl@wustl.edu [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States)

    2013-05-03

    Highlights: •Hominoid-specific oncogene TBC1D3 is targeted to plasma membrane by palmitoylation. •TBC1D3 is palmitoylated on two cysteine residues: 318 and 325. •TBC1D3 palmitoylation governs growth factors-induced TBC1D3 degradation. •Post-translational modifications may regulate oncogenic properties of TBC1D3. -- Abstract: Expression of the hominoid-specific oncoprotein TBC1D3 promotes enhanced cell growth and proliferation by increased activation of signal transduction through several growth factors. Recently we documented the role of CUL7 E3 ligase in growth factors-induced ubiquitination and degradation of TBC1D3. Here we expanded our study to discover additional molecular mechanisms that control TBC1D3 protein turnover. We report that TBC1D3 is palmitoylated on two cysteine residues: 318 and 325. The expression of double palmitoylation mutant TBC1D3:C318/325S resulted in protein mislocalization and enhanced growth factors-induced TBC1D3 degradation. Moreover, ubiquitination of TBC1D3 via CUL7 E3 ligase complex was increased by mutating the palmitoylation sites, suggesting that depalmitoylation of TBC1D3 makes the protein more available for ubiquitination and degradation. The results reported here provide novel insights into the molecular mechanisms that govern TBC1D3 protein degradation. Dysregulation of these mechanisms in vivo could potentially result in aberrant TBC1D3 expression and promote oncogenesis.

  19. TBC1D24 genotype-phenotype correlation: Epilepsies and other neurologic features.

    Science.gov (United States)

    Balestrini, Simona; Milh, Mathieu; Castiglioni, Claudia; Lüthy, Kevin; Finelli, Mattea J; Verstreken, Patrik; Cardon, Aaron; Stražišar, Barbara Gnidovec; Holder, J Lloyd; Lesca, Gaetan; Mancardi, Maria M; Poulat, Anne L; Repetto, Gabriela M; Banka, Siddharth; Bilo, Leonilda; Birkeland, Laura E; Bosch, Friedrich; Brockmann, Knut; Cross, J Helen; Doummar, Diane; Félix, Temis M; Giuliano, Fabienne; Hori, Mutsuki; Hüning, Irina; Kayserili, Hulia; Kini, Usha; Lees, Melissa M; Meenakshi, Girish; Mewasingh, Leena; Pagnamenta, Alistair T; Peluso, Silvio; Mey, Antje; Rice, Gregory M; Rosenfeld, Jill A; Taylor, Jenny C; Troester, Matthew M; Stanley, Christine M; Ville, Dorothee; Walkiewicz, Magdalena; Falace, Antonio; Fassio, Anna; Lemke, Johannes R; Biskup, Saskia; Tardif, Jessica; Ajeawung, Norbert F; Tolun, Aslihan; Corbett, Mark; Gecz, Jozef; Afawi, Zaid; Howell, Katherine B; Oliver, Karen L; Berkovic, Samuel F; Scheffer, Ingrid E; de Falco, Fabrizio A; Oliver, Peter L; Striano, Pasquale; Zara, Federico; Campeau, Phillipe M; Sisodiya, S M

    2016-07-05

    To evaluate the phenotypic spectrum associated with mutations in TBC1D24. We acquired new clinical, EEG, and neuroimaging data of 11 previously unreported and 37 published patients. TBC1D24 mutations, identified through various sequencing methods, can be found online (http://lovd.nl/TBC1D24). Forty-eight patients were included (28 men, 20 women, average age 21 years) from 30 independent families. Eighteen patients (38%) had myoclonic epilepsies. The other patients carried diagnoses of focal (25%), multifocal (2%), generalized (4%), and unclassified epilepsy (6%), and early-onset epileptic encephalopathy (25%). Most patients had drug-resistant epilepsy. We detail EEG, neuroimaging, developmental, and cognitive features, treatment responsiveness, and physical examination. In silico evaluation revealed 7 different highly conserved motifs, with the most common pathogenic mutation located in the first. Neuronal outgrowth assays showed that some TBC1D24 mutations, associated with the most severe TBC1D24-associated disorders, are not necessarily the most disruptive to this gene function. TBC1D24-related epilepsy syndromes show marked phenotypic pleiotropy, with multisystem involvement and severity spectrum ranging from isolated deafness (not studied here), benign myoclonic epilepsy restricted to childhood with complete seizure control and normal intellect, to early-onset epileptic encephalopathy with severe developmental delay and early death. There is no distinct correlation with mutation type or location yet, but patterns are emerging. Given the phenotypic breadth observed, TBC1D24 mutation screening is indicated in a wide variety of epilepsies. A TBC1D24 consortium was formed to develop further research on this gene and its associated phenotypes. © 2016 American Academy of Neurology.

  20. Parameters affecting TGO growth rate and the lifetime of TBC systems with MCrAlY-bondcoats

    Energy Technology Data Exchange (ETDEWEB)

    Toscano, J.; Naumenko, D.; Singheiser, L.; Quadakkers, W.J. [Forschungszentrum Juelich GmbH, IEF 2, Juelich (Germany); Gil, A. [AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Krakow (Poland)

    2008-06-15

    In the present work different parameters which affect the oxide growth on MCrAlY-bondcoats have been studied, in an attempt to find a reliable way to define the critical oxide thickness to failure of an EB-PVD thermal barrier coatings (TBC). It was found that the variation of selected parameters such as oxidation temperature, surface roughness, and bondcoat thickness certainly alters the thermally grown oxide (TGO) growth rate. However, simultaneously the morphology, composition, and/or microstructure of the oxide are changed, which can affect the critical TGO thickness to failure in a TBC system. In contrast, the variation of the oxygen partial pressure of the oxidizing atmosphere led to different TGO growth rates without significantly changing the oxide morphology and composition. Comparing the TGOs grown at different rates in the specimens exposed to high pO{sub 2} and low pO{sub 2} atmospheres, it was estimated that at failure the oxide scales in both specimens have reached a similar critical thickness. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

  1. Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

    Science.gov (United States)

    Sáinz, Neira; Rodríguez, Amaia; Catalán, Victoria; Becerril, Sara; Ramírez, Beatriz; Lancha, Andoni; Burgos-Ramos, Emma; Gómez-Ambrosi, Javier; Frühbeck, Gema

    2012-01-01

    Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: control, leptin-treated (1 mg/kg/d) and leptin pair-fed ob/ob mice. Microarray analysis revealed that 1,546 and 1,127 genes were regulated by leptin deficiency and leptin treatment, respectively. Among these, we identified 24 genes involved in intracellular vesicle-mediated transport in ob/ob mice. TBC1 domain family, member 1 (Tbc1d1), a negative regulator of GLUT4 translocation, was up-regulated (P = 0.001) in ob/ob mice as compared to wild types. Importantly, leptin treatment reduced the transcript levels of Tbc1d1 (P<0.001) and Tbc1d4 (P = 0.004) in the leptin-treated ob/ob as compared to pair-fed ob/ob animals. In addition, phosphorylation levels of TBC1D1 and TBC1D4 were enhanced in leptin-treated ob/ob as compared to control ob/ob (P = 0.015 and P = 0.023, respectively) and pair-fed ob/ob (P = 0.036 and P = 0.034, respectively) mice. Despite similar GLUT4 protein expression in wild type and ob/ob groups a different immunolocalization of this protein was evidenced in muscle sections. Leptin treatment increased GLUT4 immunoreactivity in gastrocnemius and extensor digitorum longus sections of leptin-treated ob/ob mice. Moreover, GLUT4 protein detected in immunoprecipitates from TBC1D4 was reduced by leptin replacement compared to control ob/ob (P = 0.013) and pair-fed ob/ob (P = 0.037) mice. Our findings suggest that leptin enhances the intracellular GLUT4 transport in skeletal muscle of ob/ob animals by reducing the expression and activity of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4. PMID:22253718

  2. TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway

    Science.gov (United States)

    Falace, Antonio; Buhler, Emmanuelle; Fadda, Manuela; Watrin, Françoise; Lippiello, Pellegrino; Pallesi-Pocachard, Emilie; Baldelli, Pietro; Benfenati, Fabio; Zara, Federico; Represa, Alfonso; Fassio, Anna; Cardoso, Carlos

    2014-01-01

    Alterations in the formation of brain networks are associated with several neurodevelopmental disorders. Mutations in TBC1 domain family member 24 (TBC1D24) are responsible for syndromes that combine cortical malformations, intellectual disability, and epilepsy, but the function of TBC1D24 in the brain remains unknown. We report here that in utero TBC1D24 knockdown in the rat developing neocortex affects the multipolar-bipolar transition of neurons leading to delayed radial migration. Furthermore, we find that TBC1D24-knockdown neurons display an abnormal maturation and retain immature morphofunctional properties. TBC1D24 interacts with ADP ribosylation factor (ARF)6, a small GTPase crucial for membrane trafficking. We show that in vivo, overexpression of the dominant-negative form of ARF6 rescues the neuronal migration and dendritic outgrowth defects induced by TBC1D24 knockdown, suggesting that TBC1D24 prevents ARF6 activation. Overall, our findings demonstrate an essential role of TBC1D24 in neuronal migration and maturation and highlight the physiological relevance of the ARF6-dependent membrane-trafficking pathway in brain development. PMID:24469796

  3. Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

    DEFF Research Database (Denmark)

    Vind, B. F.; Pehmøller, Christian; Treebak, Jonas Thue

    2011-01-01

    AIMS/HYPOTHESIS: Insulin-mediated glucose disposal rates (R (d)) are reduced in type 2 diabetic patients, a process in which intrinsic signalling defects are thought to be involved. Phosphorylation of TBC1 domain family, member 4 (TBC1D4) is at present the most distal insulin receptor signalling...... event linked to glucose transport. In this study, we examined insulin action on site-specific phosphorylation of TBC1D4 and the effect of exercise training on insulin action and signalling to TBC1D4 in skeletal muscle from type 2 diabetic patients. METHODS: During a 3 h euglycaemic-hyperinsulinaemic (80...... mU min(-1) m(-2)) clamp, we obtained M. vastus lateralis biopsies from 13 obese type 2 diabetic and 13 obese, non-diabetic control individuals before and after 10 weeks of endurance exercise-training. RESULTS: Before training, reductions in insulin-stimulated R (d), together with impaired insulin...

  4. TBC2health: a database of experimentally validated health-beneficial effects of tea bioactive compounds.

    Science.gov (United States)

    Zhang, Shihua; Xuan, Hongdong; Zhang, Liang; Fu, Sicong; Wang, Yijun; Yang, Hua; Tai, Yuling; Song, Youhong; Zhang, Jinsong; Ho, Chi-Tang; Li, Shaowen; Wan, Xiaochun

    2017-09-01

    Tea is one of the most consumed beverages in the world. Considerable studies show the exceptional health benefits (e.g. antioxidation, cancer prevention) of tea owing to its various bioactive components. However, data from these extensively published papers had not been made available in a central database. To lay a foundation in improving the understanding of healthy tea functions, we established a TBC2health database that currently documents 1338 relationships between 497 tea bioactive compounds and 206 diseases (or phenotypes) manually culled from over 300 published articles. Each entry in TBC2health contains comprehensive information about a bioactive relationship that can be accessed in three aspects: (i) compound information, (ii) disease (or phenotype) information and (iii) evidence and reference. Using the curated bioactive relationships, a bipartite network was reconstructed and the corresponding network (or sub-network) visualization and topological analyses are provided for users. This database has a user-friendly interface for entry browse, search and download. In addition, TBC2health provides a submission page and several useful tools (e.g. BLAST, molecular docking) to facilitate use of the database. Consequently, TBC2health can serve as a valuable bioinformatics platform for the exploration of beneficial effects of tea on human health. TBC2health is freely available at http://camellia.ahau.edu.cn/TBC2health. © The Author 2016. Published by Oxford University Press.

  5. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

    DEFF Research Database (Denmark)

    Szekeres, Ferenc; Chadt, Alexandra; Tom, Robby Z

    2012-01-01

    The Rab-GTPase-activating protein TBC1D1 has emerged as a novel candidate involved in metabolic regulation. Our aim was to determine whether TBC1D1 is involved in insulin as well as energy-sensing signals controlling skeletal muscle metabolism. TBC1D1-deficient congenic B6.SJL-Nob1.10 (Nob1.10(SJL...... be explained partly by a 50% reduction in GLUT4 protein, since proximal signaling at the level of Akt, AMPK, and acetyl-CoA carboxylase (ACC) was unaltered. Paradoxically, in vivo insulin-stimulated 2-deoxyglucose uptake was increased in EDL and tibialis anterior muscle from TBC1D1-deficient mice......)) and wild-type littermates were studied. Glucose and insulin tolerance, glucose utilization, hepatic glucose production, and tissue-specific insulin-mediated glucose uptake were determined. The effect of insulin, AICAR, or contraction on glucose transport was studied in isolated skeletal muscle. Glucose...

  6. The role that bond coat depletion of aluminum has on the lifetime of APS-TBC under oxidizing conditions

    Energy Technology Data Exchange (ETDEWEB)

    Renusch, D.; Schorr, M.; Schuetze, M. [Karl-Winnacker-Institut der DECHEMA e.V., D-60486 Frankfurt am Main (Germany)

    2008-07-15

    Bond coat oxidation as well as bond coat depletion of Al are still believed to be a major degradation mechanism with respect to the lifetime of thermal barrier coating (TBC) systems. In this study the top coat lifetime is described as being limited by both bond coat depletion of Al and mechanical failure of the top coat. The empirical results are introduced by considering three spallation cases, namely, Al depletion failure, thermal fatigue failure, and thermal aging failure. Al depletion failure occurs when the Al content within the bond coat reaches a critical value. In this paper bond coat depletion of Al is modeled by considering the diffusion of Al into both the thermally grown oxide (TGO) and substrate. The diffusion model results are compared to Al concentration profiles measured with an electron beam microprobe. These measured results are from oxidized air plasma sprayed TBC systems (APS-TBC) with vacuum plasma sprayed (VPS) bond coats for exposures up to 5000 h in the temperature range of 950-1100 C. This paper focuses on the Al depletion failure and how it relates to top coat spallation. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

  7. CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2.

    Directory of Open Access Journals (Sweden)

    Lin Sun

    Full Text Available Rac1 is a founding member of the Rho-GTPase family and a key regulator of membrane remodeling. In the context of apoptotic cell corpse engulfment, CED-10/Rac1 acts with its bipartite guanine nucleotide exchange factor, CED-5/Dock180-CED-12/ELMO, in an evolutionarily conserved pathway to promote phagocytosis. Here we show that in the context of the Caenorhabditis elegans intestinal epithelium CED-10/Rac1, CED-5/Dock180, and CED-12/ELMO promote basolateral recycling. Furthermore, we show that CED-10 binds to the RAB-5 GTPase activating protein TBC-2, that CED-10 contributes to recruitment of TBC-2 to endosomes, and that recycling cargo is trapped in recycling endosomes in ced-12, ced-10, and tbc-2 mutants. Expression of GTPase defective RAB-5(Q78L also traps recycling cargo. Our results indicate that down-regulation of early endosome regulator RAB-5/Rab5 by a CED-5, CED-12, CED-10, TBC-2 cascade is an important step in the transport of cargo through the basolateral recycling endosome for delivery to the plasma membrane.

  8. Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

    DEFF Research Database (Denmark)

    Chadt, Alexandra; Leicht, Katja; Deshmukh, Atul

    2008-01-01

    We previously identified Nob1 as a quantitative trait locus for high-fat diet-induced obesity and diabetes in genome-wide scans of outcross populations of obese and lean mouse strains. Additional crossbreeding experiments indicated that Nob1 represents an obesity suppressor from the lean Swiss Jim...... Lambert (SJL) strain. Here we identify a SJL-specific mutation in the Tbc1d1 gene that results in a truncated protein lacking the TBC Rab-GTPase-activating protein domain. TBC1D1, which has been recently linked to human obesity, is related to the insulin signaling protein AS160 and is predominantly...... and reduced glucose uptake in isolated skeletal muscle. Our data strongly suggest that mutation of Tbc1d1 suppresses high-fat diet-induced obesity by increasing lipid use in skeletal muscle....

  9. α-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC1D1 independently of AMPK

    DEFF Research Database (Denmark)

    Møller, Cathrine Laustrup; Kjøbsted, Rasmus; Enriori, Pablo J

    2016-01-01

    The melanocortin system includes five G-protein coupled receptors (family A) defined as MC1R-MC5R, which are stimulated by endogenous agonists derived from proopiomelanocortin (POMC). The melanocortin system has been intensely studied for its central actions in body weight and energy expenditure...... pathway involved in α-MSH-stimulated glucose uptake in differentiated L6 myotubes and mouse muscle explants. In order to examine the involvement of AMPK, we investigate -MSH stimulation in both wild type and AMPK deficient mice. We found that -MSH significantly induces phosphorylation of TBC1 domain (TBC1...

  10. Team-based care for improving hypertension management among outpatients (TBC-HTA): study protocol for a pragmatic randomized controlled trial.

    Science.gov (United States)

    Santschi, Valérie; Wuerzner, Grégoire; Chiolero, Arnaud; Burnand, Bernard; Schaller, Philippe; Cloutier, Lyne; Paradis, Gilles; Burnier, Michel

    2017-01-21

    Blood pressure (BP) is poorly controlled among a large proportion of hypertensive outpatients. Innovative models of care are therefore needed to improve BP control. The Team-Based Care for improving Hypertension management (TBC-HTA) study aims to evaluate the effect of a team-based care (TBC) interprofessional intervention, involving nurses, community pharmacists and physicians, on BP control of hypertensive outpatients compared to usual care in routine clinical practice. The TBC-HTA study is a pragmatic randomized controlled study with a 6-month follow-up which tests a TBC interprofessionnal intervention conducted among uncontrolled treated hypertensive outpatients in two ambulatory clinics and among seven nearby community pharmacies in Lausanne and Geneva, Switzerland. A total of 110 patients are being recruited and randomized to TBC (TBC: N = 55) or usual care group (UC: N = 55). Patients allocated to the TBC group receive the TBC intervention conducted by an interprofessional team, involving an ambulatory clinic nurse, a community pharmacist and a physician. A nurse and a community pharmacist meet patients every 6 weeks to measure BP, to assess lifestyle, to estimate medication adherence, and to provide education to the patient about disease, treatment and lifestyle. After each visit, the nurse and pharmacist write a summary report with recommendations related to medication adherence, lifestyle, and changes in therapy. The physician then adjusts antihypertensive therapy accordingly. Patients in the UC group receive usual routine care without sessions with a nurse and a pharmacist. The primary outcome is the difference in daytime ambulatory BP between TBC and UC patients at 6-month of follow-up. Secondary outcomes include patients' and healthcare professionals' satisfaction with the TBC intervention and BP control at 12 months (6 months after the end of the intervention). This ongoing study aims to evaluate the effect of a newly developed team

  11. TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy.

    Science.gov (United States)

    Falace, Antonio; Filipello, Fabia; La Padula, Veronica; Vanni, Nicola; Madia, Francesca; De Pietri Tonelli, Davide; de Falco, Fabrizio A; Striano, Pasquale; Dagna Bricarelli, Franca; Minetti, Carlo; Benfenati, Fabio; Fassio, Anna; Zara, Federico

    2010-09-10

    Idiopathic epilepsies (IEs) are a group of disorders characterized by recurrent seizures in the absence of detectable brain lesions or metabolic abnormalities. IEs include common disorders with a complex mode of inheritance and rare Mendelian traits suggesting the occurrence of several alleles with variable penetrance. We previously described a large family with a recessive form of idiopathic epilepsy, named familial infantile myoclonic epilepsy (FIME), and mapped the disease locus on chromosome 16p13.3 by linkage analysis. In the present study, we found that two compound heterozygous missense mutations (D147H and A509V) in TBC1D24, a gene of unknown function, are responsible for FIME. In situ hybridization analysis revealed that Tbc1d24 is mainly expressed at the level of the cerebral cortex and the hippocampus. By coimmunoprecipitation assay we found that TBC1D24 binds ARF6, a Ras-related family of small GTPases regulating exo-endocytosis dynamics. The main recognized function of ARF6 in the nervous system is the regulation of dendritic branching, spine formation, and axonal extension. TBC1D24 overexpression resulted in a significant increase in neurite length and arborization and the FIME mutations significantly reverted this phenotype. In this study we identified a gene mutation involved in autosomal-recessive idiopathic epilepsy, unveiled the involvement of ARF6-dependent molecular pathway in brain hyperexcitability and seizures, and confirmed the emerging role of subtle cytoarchitectural alterations in the etiology of this group of common epileptic disorders. 2010 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  12. TBC1D24 Mutations in a Sibship with Multifocal Polymyoclonus

    Directory of Open Access Journals (Sweden)

    Adeline Ngoh

    2017-04-01

    Full Text Available Background: Advances in molecular genetic technologies have improved our understanding of genetic causes of rare neurological disorders with features of myoclonus.Case Report: A family with two affected siblings, presenting with multifocal polymyoclonus and neurodevelopmental delay, was recruited for whole-exome sequencing following unyielding diagnostic neurometabolic investigations. Compound heterozygous mutations in TBC1D24, a gene previously associated with various epilepsy phenotypes and hearing loss, were identified in both siblings. The mutations included a missense change c.457G>A (p.Glu157Lys, and a novel frameshift mutation c.545del (p.Thr182Serfs*6.Discussion: We propose that TBC1D24-related diseases should be in the differential diagnosis for children with polymyoclonus. 

  13. Characterization of alumina scales formed during isothermal and cyclic oxidation of plasma-sprayed TBC systems at 1150 C

    International Nuclear Information System (INIS)

    Haynes, J.A.; Ferber, M.K.; Porter, W.D.; Rigney, E.D.

    1999-01-01

    The isothermal- and cyclic-oxidation behavior of thermal barrier coating (TBC) systems consisting of vacuum plasma-sprayed (VPS) Ni-22Cr-10Al/Y (wt%) bond coatings and air plasma-sprayed (APS) Y 2 O 3 -stabilized ZrO 2 (YSZ) top coatings (on single-crystal superalloys) was investigated. The microstructures, flaw contents, and fracture behavior of the Al 2 O 3 scales formed during oxidation testing at 1150 C were characterized (by analysis of coating and scale fracture surfaces and metallographic cross sections). Significant localized fracture and buckling of the Al 2 O 3 scales that formed along the bond-coat--top-coat interfaces were observed after cyclic oxidation of TBCs. However, substantial amounts of localized scale damage did not induce rapid TBC failure. Decohesion of the columnar alumina scales on the rough bond-coat surfaces occurred by both internal Al 2 O 3 fracture (parallel to the metal surface) and oxide-metal delamination. There were microstructural indications of Al 2 O 3 scale crack healing by sintering into planar arrays of voids. Alumina scales that formed on convex NiCrAlY surfaces (with radii of 50 microm or less) after cyclic oxidation, whereas scales formed by isothermal oxidation contained few visible voids. Accelerated void growth in Al 2 O 3 scales on the irregular NiCrAlY surfaces appeared to be creep-related and was attributed to the synergistic effects of geometric and thermal stresses

  14. Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.

    Science.gov (United States)

    Zhao, Huzi; Zhang, Lina; Zhang, Yongchen; Zhao, Lei; Wan, Qing; Wang, Bei; Bu, Xiaodong; Wan, Meiling; Shen, Chuanlu

    2017-05-30

    The hominoid oncoprotein TBC1D3 enhances growth factor (GF) signaling and GF signaling, conversely, induces the ubiquitination and subsequent degradation of TBC1D3. However, little is known regarding the regulation of this degradation, and the role of TBC1D3 in the progression of tumors has also not been defined. In the present study, we demonstrated that calmodulin (CaM), a ubiquitous cellular calcium sensor, specifically interacted with TBC1D3 in a Ca2+-dependent manner and inhibited GF signaling-induced ubiquitination and degradation of the oncoprotein in both cytoplasm and nucleus of human breast cancer cells. The CaM-interacting site of TBC1D3 was mapped to amino acids 157~171, which comprises two 1-14 hydrophobic motifs and one lysine residue (K166). Deletion of these motifs was shown to abolish interaction between TBC1D3 and CaM. Surprisingly, this deletion mutation caused inability of GF signaling to induce the ubiquitination and subsequent degradation of TBC1D3. In agreement with this, we identified lysine residue 166 within the CaM-interacting motifs of TBC1D3 as the actual site for the GF signaling-induced ubiquitination using mutational analysis. Point mutation of this lysine residue exhibited the same effect on TBC1D3 as the deletion mutant, suggesting that CaM inhibits GF signaling-induced degradation of TBC1D3 by occluding its ubiquitination at K166. Notably, we found that TBC1D3 promoted the expression and activation of MMP-9 and the migration of MCF-7 cells. Furthermore, interaction with CaM considerably enhanced such effect of TBC1D3. Taken together, our work reveals a novel model by which CaM promotes cell migration through inhibiting the ubiquitination and degradation of TBC1D3.

  15. Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

    DEFF Research Database (Denmark)

    Treebak, Jonas Thue; Frøsig, Christian; Pehmøller, Christian

    2009-01-01

    .01). However, TBC1D4 phosphorylation on Ser-318, Ser-341, Ser-588 and Ser-751 was higher in the previously exercised leg, both in the absence and in the presence of insulin (p power = 0.39). 14-3-3 binding capacity for TBC1D4 increased equally (p

  16. Incremento della Diffusione della TBC nella ASLRM E

    Directory of Open Access Journals (Sweden)

    E. Di Rosa

    2003-05-01

    Full Text Available

    Nell’ultimo decennio, anche nei paesi industrializzati, si è registrato un aumento dei casi di tubercolosi. Questo lavoro ha come obiettivo l’analisi dell’andamento della diffusione della tubercolosi nell’ambito della popolazione del Distretto B della ASL RM E, mediante l’elaborazione dei dati relativi alle notifiche di malattie infettive pervenute negli anni 2000 e 2001.

    Metodi: sono stati prese in considerazione le notifiche di casi di TBC pervenute negli anni 2000, 2001 alla Unità Operativa Epidemiologia e Profilassi del Servizio di Igiene e Sanità Pubblica della ASL RM E, relative e cittadini Italiani e Stranieri residenti nell’ambito territoriale del Distretto B (Municipi XIX e XX del Comune di Roma. I dati sono raccolti su supporto magnetico sono stati elaborati con software per elaborazioni dati (Access e Excel MICROSOFT per la determinazione dei tassi di incidenza grezzi, specifici e standardizzati.

    Risultati: sono pervenute 127 notifiche: Tassi grezzi; 1 Totale: 2000 = 15,67 per 100000, 2001 = 17,87 per 100000 abitanti; 2 cittadini Italiani: 2000 = 10.98 per 100000 abitanti,2001 = 11,65 per 100000; 3 Stranieri residenti: 2000 = 72,26 per 100000, 2001 = 132, 47. per 100000. Tassi standardizzati; 1 Totale: 2000 = 15,81 per 100000, 2001 = 20,97 per 100000; 2 cittadini Italiani: 2000 = 11.07
    per 100000 abitanti, 2001 = 11,7 per 100000 abitanti;
    3 cittadini stranieri: 2000 = 65,28 per 100000, 2001 = 109, 66 per 100000.

    Conclusioni: dal confronto con l’andamento delle notifiche nella ASL RM E dal 1996 a oggi si rileva un incremento delle notifiche di TBC. L’aumento è particolarmente evidente nell’ambito della popolazione immigrata. Con i dati a disposizione non è possibile valutare l’eventuale ruolo di fattori favorenti la diffusione della TBC, senza dubbio l’immigrazione gioca un ruolo rilevante in tale aumento.

  17. The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle

    DEFF Research Database (Denmark)

    Stöckli, Jacqueline; Meoli, Christopher C; Hoffman, Nolan J

    2015-01-01

    Insulin and exercise stimulate glucose uptake into skeletal muscle via different pathways. Both stimuli converge on the translocation of the glucose transporter GLUT4 from intracellular vesicles to the cell surface. Two Rab guanosine triphosphatases-activating proteins (GAPs) have been implicated...... weight, insulin action, and exercise. TBC1D1(-/-) mice showed normal glucose and insulin tolerance, with no difference in body weight compared with wild-type littermates. GLUT4 protein levels were reduced by ∼40% in white TBC1D1(-/-) muscle, and TBC1D1(-/-) mice showed impaired exercise endurance...... together with impaired exercise-mediated 2-deoxyglucose uptake into white but not red muscles. These findings indicate that the RabGAP TBC1D1 plays a key role in regulating GLUT4 protein levels and in exercise-mediated glucose uptake in nonoxidative muscle fibers....

  18. Effect of Hf Additions to Pt Aluminide Bond Coats on EB-PVD TBC Life

    Science.gov (United States)

    Nesbitt, James; Nagaraj, Ben; Williams, Jeffrey

    2000-01-01

    Small Hf additions were incorporated into a Pt aluminide coating during chemical vapor deposition (CVD) on single crystal RENE N5 substrates. Standard yttria-stabilized zirconia top coats were subsequently deposited onto the coated substrates by electron beam-physical vapor deposition (EB-PVD). The coated substrates underwent accelerated thermal cycle testing in a furnace at a temperature in excess of 1121 C (2050 F) (45 minute hot exposure, 15 minute cool to approximately 121 C (250 F)) until the thermal barrier coating (TBC) failed by spallation. Incorporating Hf in the bond coat increased the TBC life by slightly more than three times that of a baseline coating without added Hf. Scanning electron microscopy of the spalled surfaces indicated that the presence of the Hf increased the adherence of the thermally grown alumina to the Pt aluminide bond coat. The presence of oxide pegs growing into the coating from the thermally grown alumina may also partially account for the improved TBC life by creating a near-surface layer with a graded coefficient of thermal expansion.

  19. Clinical intrafamilial variability in lethal familial neonatal seizure disorder caused by TBC1D24 mutations.

    Science.gov (United States)

    Lozano, Reymundo; Herman, Kristin; Rothfuss, Melanie; Rieger, Hillary; Bayrak-Toydemir, Pinar; Aprile, Davide; Fruscione, Floriana; Zara, Federico; Fassio, Anna

    2016-12-01

    TBC1D24-related disorders include a wide phenotypic ranging from mild to lethal seizure disorders, non-syndromic deafness, and composite syndromes such as DOORS (deafness, onychodystrophy, osteodystrophy, mental retardation, and seizures). The TBC1D24 gene has a role in cerebral cortex development and in presynaptic neurotransmission. Here, we present a familial case of a lethal early-onset epileptic encephalopathy, associated with two novel compound heterozygous missense variants on the TBC1D24 gene, which were detected by exome sequencing. The detailed clinical data of the three siblings is summarized in order to support the variability of the phenotype, severity, and progression of this disorder among these family members. Functional studies demonstrated that the identified novel missense mutations result in a loss of expression of the protein, suggesting a correlation between residual expression, and the disease severity. This indicates that protein expression analysis is important for interpreting genetic results when novel variants are found, as well as for complementing clinical assessment by predicting the functional impact. Further analysis is necessary to delineate the clinical presentation of individuals with TBC1D24 pathogenic variants, as well as to develop markers for diagnosis, prognosis, and potential targeted treatments. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  20. TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

    Science.gov (United States)

    Hannemann, Mandy; Sasidharan, Nikhil; Hegermann, Jan; Kutscher, Lena M; Koenig, Sabine; Eimer, Stefan

    2012-01-01

    Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for removal of factors that would otherwise interfere with DCV release. Previously, we have shown that the GTPase, RAB-2, and its effector, RIC-19, are involved in DCV maturation in Caenorhabditis elegans motoneurons. In rab-2 mutants, specific cargo is lost from maturing DCVs and missorted into the endosomal/lysosomal degradation route. Cargo loss could be prevented by blocking endosomal delivery. This suggests that RAB-2 is involved in retention of DCV components during the sorting process at the Golgi-endosomal interface. To understand how RAB-2 activity is regulated at the Golgi, we screened for RAB-2-specific GTPase activating proteins (GAPs). We identified a potential RAB-2 GAP, TBC-8, which is exclusively expressed in neurons and which, when depleted, shows similar DCV maturation defects as rab-2 mutants. We could demonstrate that RAB-2 binds to its putative GAP, TBC-8. Interestingly, TBC-8 also binds to the RAB-2 effector, RIC-19. This interaction appears to be conserved as TBC-8 also interacted with the human ortholog of RIC-19, ICA69. Therefore, we propose that a dynamic ON/OFF cycling of RAB-2 at the Golgi induced by the GAP/effector complex is required for proper DCV maturation.

  1. Caso Clínico de la Unidad de Medicina Interna Integral: T.B.C. miliar con tuberculomas del Sistema Nervioso Central

    Directory of Open Access Journals (Sweden)

    Análida E. Pinilla Roa

    1995-04-01

    Full Text Available El caso presentado deja algunas enseñanzas y reflexiones: la primo infección progresa a TBC pulmonar en un 10%, el resto de casos de TBC son consecutivos a una reactivación, la cual sucede por diferentes situaciones que disminuyen temporalmente la capacidad inmune celular (31. El pronóstico cobijen organismos públicos y privados e integren las acciones administrativas, al igual que, el trabajo interdisciplinario de los profesionales del área de la salud para lograr que: los pacientes completen el tratamiento, prevenir la TBC con farmacoresistencia y disminuir la aparición de casos nuevos. Finalmente, es vital el trabajo en equipo interdisciplinario para lograr el diagnóstico, tratamiento, seguimiento y curación del paciente con TBC.

  2. Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.

    Science.gov (United States)

    Wang, Bei; Zhao, Huzi; Zhao, Lei; Zhang, Yongchen; Wan, Qing; Shen, Yong; Bu, Xiaodong; Wan, Meiling; Shen, Chuanlu

    2017-11-01

    Metastatic spread of cancer cells is the most life-threatening aspect of breast cancer and involves multiple steps including cell migration. We recently found that the TBC1D3 oncogene promotes the migration of breast cancer cells, and its interaction with CaM enhances the effects of TBC1D3. However, little is known regarding the mechanism by which TBC1D3 induces the migration of cancer cells. Here, we demonstrated that TBC1D3 stimulated the expression of oxidized low density lipoprotein receptor 1 (OLR1), a stimulator of cell migration, in breast cancer cells at the transcriptional level. Depletion of OLR1 by siRNAs or down-regulation of OLR1 expression using pomalidomide, a TNFα inhibitor, significantly decreased TBC1D3-induced migration of these cells. Notably, TBC1D3 overexpression activated NF-κB, a major effector of TNFα signaling, while inhibition of TNFα signaling suppressed the effects of TBC1D3. Consistent with this, NF-κB inhibition using its specific inhibitor caffeic acid phenethyl ester decreased both TBC1D3-induced OLR1 expression and cell migration, suggesting a critical role for TNFα/NF-κB signaling in TBC1D3-induced migration of breast cancer cells. Mechanistically, TBC1D3 induced activation of this signaling pathway on multiple levels, including by increasing the release of TNFα, elevating the transcription of TNFR1, TRAF1, TRAF5 and TRAF6, and decreasing the degradation of TNFR1. In summary, these studies identify the TBC1D3 oncogene as a novel regulator of TNFα/NF-κB signaling that mediates this oncogene-induced migration of human breast cancer cells by up-regulating OLR1. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes.

    Science.gov (United States)

    Manousaki, Despoina; Kent, Jack W; Haack, Karin; Zhou, Sirui; Xie, Pingxing; Greenwood, Celia M; Brassard, Paul; Newman, Deborah E; Cole, Shelley; Umans, Jason G; Rouleau, Guy; Comuzzie, Anthony G; Richards, J Brent

    2016-11-01

    A common nonsense mutation in TBC1D4 was recently found to substantially increase the odds of type 2 diabetes in Greenlandic Inuit, leading to exclusively increased postprandial glucose. We investigated the frequency and effect of the TBC1D4 mutation on glucose metabolism and type 2 diabetes diagnosis among Canadian and Alaskan Inuit. Exome sequencing of the TBC1D4 variant was performed in 114 Inuit from Nunavik, Canada, and Sanger sequencing was undertaken in 1,027 Alaskan Inuit from the Genetics of Coronary Artery Disease in Alaskan Natives (GOCADAN) Study. Association testing evaluated the effect of the TBC1D4 variant on diabetes-related metabolic traits and diagnosis. The TBC1D4 mutation was present in 27% of Canadian and Alaskan Inuit. It was strongly associated with higher glucose (effect size +3.3 mmol/L; P = 2.5 x 10 -6 ) and insulin (effect size +175 pmol/L; P = 0.04) 2 h after an oral glucose load in homozygote carriers. TBC1D4 carriers with prediabetes and type 2 diabetes had an increased risk of remaining undiagnosed unless postprandial glucose values were tested (odds ratio 5.4 [95% CI 2.5-12]) compared with noncarriers. Of carriers with prediabetes or type 2 diabetes, 32% would remain undiagnosed without an oral glucose tolerance test (OGTT). Disruption of TBC1D4 is common among North American Inuit, resulting in exclusively elevated postprandial glucose. This leads to underdiagnosis of type 2 diabetes, unless an OGTT is performed. Accounting for genetic factors in the care of Inuit with diabetes provides an opportunity to implement precision medicine in this population. © 2016 by the American Diabetes Association.

  4. Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes

    Science.gov (United States)

    Liu, Ou; Grant, Barth D.

    2015-01-01

    The small GTPase RAB-5/Rab5 is a master regulator of the early endosome, required for a myriad of coordinated activities, including the degradation and recycling of internalized cargo. Here we focused on the recycling function of the early endosome and the regulation of RAB-5 by GAP protein TBC-2 in the basolateral C. elegans intestine. We demonstrate that downstream basolateral recycling regulators, GTPase RAB-10/Rab10 and BAR domain protein AMPH-1/Amphiphysin, bind to TBC-2 and help to recruit it to endosomes. In the absence of RAB-10 or AMPH-1 binding to TBC-2, RAB-5 membrane association is abnormally high and recycling cargo is trapped in early endosomes. Furthermore, the loss of TBC-2 or AMPH-1 leads to abnormally high spatial overlap of RAB-5 and RAB-10. Taken together our results indicate that RAB-10 and AMPH-1 mediated down-regulation of RAB-5 is an important step in recycling, required for cargo exit from early endosomes and regulation of early endosome–recycling endosome interactions. PMID:26393361

  5. TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans

    Science.gov (United States)

    Hannemann, Mandy; Sasidharan, Nikhil; Hegermann, Jan; Kutscher, Lena M.; Koenig, Sabine; Eimer, Stefan

    2012-01-01

    Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for removal of factors that would otherwise interfere with DCV release. Previously, we have shown that the GTPase, RAB-2, and its effector, RIC-19, are involved in DCV maturation in Caenorhabditis elegans motoneurons. In rab-2 mutants, specific cargo is lost from maturing DCVs and missorted into the endosomal/lysosomal degradation route. Cargo loss could be prevented by blocking endosomal delivery. This suggests that RAB-2 is involved in retention of DCV components during the sorting process at the Golgi-endosomal interface. To understand how RAB-2 activity is regulated at the Golgi, we screened for RAB-2–specific GTPase activating proteins (GAPs). We identified a potential RAB-2 GAP, TBC-8, which is exclusively expressed in neurons and which, when depleted, shows similar DCV maturation defects as rab-2 mutants. We could demonstrate that RAB-2 binds to its putative GAP, TBC-8. Interestingly, TBC-8 also binds to the RAB-2 effector, RIC-19. This interaction appears to be conserved as TBC-8 also interacted with the human ortholog of RIC-19, ICA69. Therefore, we propose that a dynamic ON/OFF cycling of RAB-2 at the Golgi induced by the GAP/effector complex is required for proper DCV maturation. PMID:22654674

  6. TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Mandy Hannemann

    Full Text Available Dense core vesicles (DCVs are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for removal of factors that would otherwise interfere with DCV release. Previously, we have shown that the GTPase, RAB-2, and its effector, RIC-19, are involved in DCV maturation in Caenorhabditis elegans motoneurons. In rab-2 mutants, specific cargo is lost from maturing DCVs and missorted into the endosomal/lysosomal degradation route. Cargo loss could be prevented by blocking endosomal delivery. This suggests that RAB-2 is involved in retention of DCV components during the sorting process at the Golgi-endosomal interface. To understand how RAB-2 activity is regulated at the Golgi, we screened for RAB-2-specific GTPase activating proteins (GAPs. We identified a potential RAB-2 GAP, TBC-8, which is exclusively expressed in neurons and which, when depleted, shows similar DCV maturation defects as rab-2 mutants. We could demonstrate that RAB-2 binds to its putative GAP, TBC-8. Interestingly, TBC-8 also binds to the RAB-2 effector, RIC-19. This interaction appears to be conserved as TBC-8 also interacted with the human ortholog of RIC-19, ICA69. Therefore, we propose that a dynamic ON/OFF cycling of RAB-2 at the Golgi induced by the GAP/effector complex is required for proper DCV maturation.

  7. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

    Science.gov (United States)

    Ju, Xiang-Chun; Hou, Qiong-Qiong; Sheng, Ai-Li; Wu, Kong-Yan; Zhou, Yang; Jin, Ying; Wen, Tieqiao; Yang, Zhengang; Wang, Xiaoqun; Luo, Zhen-Ge

    2016-01-01

    Cortical expansion and folding are often linked to the evolution of higher intelligence, but molecular and cellular mechanisms underlying cortical folding remain poorly understood. The hominoid-specific gene TBC1D3 undergoes segmental duplications during hominoid evolution, but its role in brain development has not been explored. Here, we found that expression of TBC1D3 in ventricular cortical progenitors of mice via in utero electroporation caused delamination of ventricular radial glia cells (vRGs) and promoted generation of self-renewing basal progenitors with typical morphology of outer radial glia (oRG), which are most abundant in primates. Furthermore, down-regulation of TBC1D3 in cultured human brain slices decreased generation of oRGs. Interestingly, localized oRG proliferation resulting from either in utero electroporation or transgenic expression of TBC1D3, was often found to underlie cortical regions exhibiting folding. Thus, we have identified a hominoid gene that is required for oRG generation in regulating the cortical expansion and folding. DOI: http://dx.doi.org/10.7554/eLife.18197.001 PMID:27504805

  8. Moisture-Induced TBC Spallation on Turbine Blade Samples

    Science.gov (United States)

    Smialek, James

    2011-01-01

    Delayed failure of TBCs is a widely observed laboratory phenomenon, although many of the early observations went unreported. The weekend effect or DeskTop Spallation (DTS) is characterized by initial survival of a TBC after accelerated laboratory thermal cycling, then failure by exposure to ambient humidity or water. Once initiated, failure can occur quite dramatically in less than a second. To this end, the water drop test and digital video recordings have become useful techniques in studies at NASA (Smialek, Zhu, Cuy), DECHMA (Rudolphi, Renusch, Schuetze), and CNRS Toulouse/SNECMA (Deneux, Cadoret, Hervier, Monceau). In the present study the results for a commercial turbine blade, with a standard EB-PVD 7YSZ TBC top coat and Pt-aluminide diffusion bond coat are reported. Cut sections were intermittently oxidized at 1100, 1150, and 1200 C and monitored by weight change and visual appearance. Failures were distributed widely over a 5-100 hr time range, depending on temperature. At some opportune times, failure was captured by video recording, documenting the appearance and speed of the moisture-induced spallation process. Failure interfaces exhibited alumina scale grains, decorated with Ta-rich oxide particles, and alumina inclusions as islands and streamers. The phenomenon is thus rooted in moisture-induced delayed spallation (MIDS) of the alumina scale formed on the bond coat. In that regard, many studies show the susceptibility of alumina scales to moisture, as long as high strain energy and a partially exposed interface exist. The latter conditions result from severe cyclic oxidation conditions, which produce a highly stressed and partially damaged scale. In one model, it has been proposed that moisture reacts with aluminum in the bond coat to release hydrogen atoms that embrittle the interface. A negative synergistic effect with interfacial sulfur is also invoked.

  9. Sulfur and Moisture Effects on Alumina Scale and TBC Spallation

    Science.gov (United States)

    Smialek, James L.

    2007-01-01

    cause is related to a hydrogen embrittlement reaction: Al alloy + 3 H2O = Al(OH)3 + 3H(+) + 3e(-). This mechanism is derived from an analogous moisture-induced hydrogen embrittlement mechanism originally shown for Ni3Al and FeAl intermetallics. Consequently, a cathodic hydrogen charging technique was used to demonstrate that electrolytic de-scaling occurs for these otherwise adherent alumina scales formed on Y-doped Rene'N5, in support of hydrogen effects. Finally, some TBC observations are discussed in light of all of the above. Plasma sprayed 8YSZ coatings, produced on PWA1484 without a bond coat, were found to survive more than 1000 1-hr cycles at 1100 C when desulfurized to below 0.1 ppmw. At higher sulfur (1.2 ppmw) levels, moisture sensitivity and delayed TBC failure, referred to as Desk Top Spallation, occurred at just 200 hr. Despite a large degree of scatter, a factor of 5 in life improvement is indicated for desulfurized samples in cyclic furnace tests, confirming the beneficial effect of low sulfur alloys on model TBC systems. (DTS and moisture effects are also observed on commercially applied PVD 7YSZ coatings on Rene'N5+Y with Pt-aluminide bond coats). These types of catastrophic failure were subverted on the model system by segmenting the substrate into a network of 0.010 high ribs, spaced in. apart, prior to plasma spraying. No failures occurred after 1000 cycles at 1150 C or after 2000 cycles at 1100 C, even after water immersion. The benefit is described in terms of elasticity models and a critical buckling stress.

  10. Reactivation of pulmonary tuberculosis (TBC) with the use of antagonist of the tumor necrosis factor alpha (FNTα) in rheumatoid arthritis: On purpose of a case

    International Nuclear Information System (INIS)

    Martinez V, Jose B; Medina V, Yimy F; Parga, Roberto; Restrepo, Jose Felix; Iglesias G, Antonio; Rondon, Federico

    2005-01-01

    Woman 56 years old, with history of rheumatoid arthritis who develops reactivation of pulmonary tuberculosis (TBC) after 1 year of treatment with biological therapy (antagonist of the tumor necrosis factor alpha). It is discussed pathophysiologic mechanisms, diagnostic approach, treatment of TBC and some recommendations for the use of biological therapy in patients with rheumatic disease

  11. Affinity between TBC1D4 (AS160 phosphotyrosine-binding domain and insulin-regulated aminopeptidase cytoplasmic domain measured by isothermal titration calorimetry

    Directory of Open Access Journals (Sweden)

    SangYoun Park*, Keon Young Kim, Sunmin Kim & Young Seok Yu

    2012-06-01

    Full Text Available Uptake of circulating glucose into the cells happens via the insulin-mediated signalling pathway, which translocates the glucosetransporter 4 (GLUT4 vesicles from the intracellular compartmentto the plasma membrane. RabㆍGTPases are involvedin this vesicle trafficking, where RabㆍGTPase-activatingproteins (RabGAP enhance the GTP to GDP hydrolysis.TBC1D4 (AS160 and TBC1D1 are functional RabGAPs in theadipocytes and the skeletonal myocytes, respectively. Theseproteins contain two phosphotyrosine-binding domains (PTBsat the amino-terminus of the catalytic RabGAP domain. Thesecond PTB has been shown to interact with the cytoplasmicregion of the insulin-regulated aminopeptidase (IRAP of theGLUT4 vesicle. In this study, we quantitatively measured the∼μM affinity (KD between TBC1D4 PTB and IRAP using isothermaltitration calorimetry, and further showed that IRAP residues1-49 are the major region mediating this interaction. Wealso demonstrated that the IRAP residues 1-15 are necessarybut not sufficient for the PTB interaction.

  12. TOPSIS based parametric optimization of laser micro-drilling of TBC coated nickel based superalloy

    Science.gov (United States)

    Parthiban, K.; Duraiselvam, Muthukannan; Manivannan, R.

    2018-06-01

    The technique for order of preference by similarity ideal solution (TOPSIS) approach was used for optimizing the process parameters of laser micro-drilling of nickel superalloy C263 with Thermal Barrier Coating (TBC). Plasma spraying was used to deposit the TBC and a pico-second Nd:YAG pulsed laser was used to drill the specimens. Drilling angle, laser scan speed and number of passes were considered as input parameters. Based on the machining conditions, Taguchi L8 orthogonal array was used for conducting the experimental runs. The surface roughness and surface crack density (SCD) were considered as the output measures. The surface roughness was measured using 3D White Light Interferometer (WLI) and the crack density was measured using Scanning Electron Microscope (SEM). The optimized result achieved from this approach suggests reduced surface roughness and surface crack density. The holes drilled at an inclination angle of 45°, laser scan speed of 3 mm/s and 400 number of passes found to be optimum. From the Analysis of variance (ANOVA), inclination angle and number of passes were identified as the major influencing parameter. The optimized parameter combination exhibited a 19% improvement in surface finish and 12% reduction in SCD.

  13. Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

    DEFF Research Database (Denmark)

    Middelbeek, R J W; Chambers, M A; Tantiwong, P

    2013-01-01

    Individuals with obesity and type 2 diabetes (T2D) are typically insulin resistant, exhibiting impaired skeletal muscle glucose uptake. Animal and cell culture experiments have shown that site-specific phosphorylation of the Rab-GTPase-activating proteins AS160 and TBC1D1 is critical for GLUT4 tr...

  14. Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration.

    Science.gov (United States)

    Fernandes, Ana Clara; Uytterhoeven, Valerie; Kuenen, Sabine; Wang, Yu-Chun; Slabbaert, Jan R; Swerts, Jef; Kasprowicz, Jaroslaw; Aerts, Stein; Verstreken, Patrik

    2014-11-24

    Synaptic demise and accumulation of dysfunctional proteins are thought of as common features in neurodegeneration. However, the mechanisms by which synaptic proteins turn over remain elusive. In this paper, we study Drosophila melanogaster lacking active TBC1D24/Skywalker (Sky), a protein that in humans causes severe neurodegeneration, epilepsy, and DOOR (deafness, onychdystrophy, osteodystrophy, and mental retardation) syndrome, and identify endosome-to-lysosome trafficking as a mechanism for degradation of synaptic vesicle-associated proteins. In fly sky mutants, synaptic vesicles traveled excessively to endosomes. Using chimeric fluorescent timers, we show that synaptic vesicle-associated proteins were younger on average, suggesting that older proteins are more efficiently degraded. Using a genetic screen, we find that reducing endosomal-to-lysosomal trafficking, controlled by the homotypic fusion and vacuole protein sorting (HOPS) complex, rescued the neurotransmission and neurodegeneration defects in sky mutants. Consistently, synaptic vesicle proteins were older in HOPS complex mutants, and these mutants also showed reduced neurotransmission. Our findings define a mechanism in which synaptic transmission is facilitated by efficient protein turnover at lysosomes and identify a potential strategy to suppress defects arising from TBC1D24 mutations in humans. © 2014 Fernandes et al.

  15. Design and optimization of coating structure for the thermal barrier coatings fabricated by atmospheric plasma spraying via finite element method

    Directory of Open Access Journals (Sweden)

    L. Wang

    2014-06-01

    Full Text Available The first prerequisite for fabricating the thermal barrier coatings (TBCs with excellent performance is to find an optimized coating structure with high thermal insulation effect and low residual stress. This paper discusses the design and optimization of a suitable coating structure for the TBCs prepared by atmospheric plasma spraying (APS using the finite element method. The design and optimization processes comply with the rules step by step, as the structure develops from a simple to a complex one. The research results indicate that the suitable thicknesses of the bond-coating and top-coating are 60–120 μm and 300–420 μm, respectively, for the single ceramic layer YSZ/NiCoCrAlY APS-TBC. The embedded interlayer (50 wt.%YSZ + 50 wt.%NiCoCrAlY will further reduce the residual stress without sacrificing the thermal insulation effect. The double ceramic layer was further considered which was based on the single ceramic layer TBC. The embedded interlayer and the upper additional ceramic layer will have a best match between the low residual stress and high thermal insulation effect. Finally, the optimized coating structure was obtained, i.e., the La2Ce2O7(LC/YSZ/Interlayer/NiCoCrAlY coating structure with appropriate layer thickness is the best choice. The effective thermal conductivity of this optimized LC/YSZ/IL/BL TBC is 13.2% lower than that of the typical single ceramic layer YSZ/BL TBC.

  16. Structural and population-based evaluations of TBC1D1 p.Arg125Trp.

    Directory of Open Access Journals (Sweden)

    Tom G Richardson

    Full Text Available Obesity is now a leading cause of preventable death in the industrialised world. Understanding its genetic influences can enhance insight into molecular pathogenesis and potential therapeutic targets. A non-synonymous polymorphism (rs35859249, p.Arg125Trp in the N-terminal TBC1D1 phosphotyrosine-binding (PTB domain has shown a replicated association with familial obesity in women. We investigated these findings in the Avon Longitudinal Study of Parents and Children (ALSPAC, a large European birth cohort of mothers and offspring, and by generating a predicted model of the structure of this domain. Structural prediction involved the use of three separate algorithms; Robetta, HHpred/MODELLER and I-TASSER. We used the transmission disequilibrium test (TDT to investigate familial association in the ALSPAC study cohort (N = 2,292 mother-offspring pairs. Linear regression models were used to examine the association of genotype with mean measurements of adiposity (Body Mass Index (BMI, waist circumference and Dual-energy X-ray absorptiometry (DXA assessed fat mass, and logistic regression was used to examine the association with odds of obesity. Modelling showed that the R125W mutation occurs in a location of the TBC1D1 PTB domain that is predicted to have a function in a putative protein:protein interaction. We did not detect an association between R125W and BMI (mean per allele difference 0.27 kg/m(2 (95% Confidence Interval: 0.00, 0.53 P = 0.05 or obesity (odds ratio 1.01 (95% Confidence Interval: 0.77, 1.31, P = 0.96 in offspring after adjusting for multiple comparisons. Furthermore, there was no evidence to suggest that there was familial association between R125W and obesity (χ(2 = 0.06, P = 0.80. Our analysis suggests that R125W in TBC1D1 plays a role in the binding of an effector protein, but we find no evidence that the R125W variant is related to mean BMI or odds of obesity in a general population sample.

  17. Technical study report on fuel fabrication system

    International Nuclear Information System (INIS)

    Kono, Shusaku; Tanaka, Kenya; Ono, Kiyoshi; Iwasa, Katsuyoshi; Hoshino, Yasushi; Shinkai, Yasuo

    2000-07-01

    The feasibility study of FBR and related fuel cycle is performed for developing the FBR recycle system which ensures safety, economic competitiveness, efficient utilization of resources, reduction of environmental burden and enhancement of nuclear non-proliferation under consistency of FBR reactor and fuel cycle systems. In this study, a conceptual design study and system characteristics evaluation are conducted for fuel fabrication systems of pellet process, vibropack process for oxide and nitride fuel and casting process for metal fuel. Technical issues in each process are also extracted. In 1999 fiscal year, a conceptual design study were conducted for the fuel fabrication plants adopting (1) the short pellet process which simplifies the conventional MOX pellet fabrication processes, (2) vibropack processes of aqueous gelation process, improved RIAR process, improved ANL process and fluoride volatility process, (3) casting processes of injection process, centrifuging process. As a result, attainable perspective was obtained for each fuel fabrication system through the evaluation of apparatuses, layout and facility volume, etc. In each fuel fabrication system, technical issues for practical use were made clear. Hereafter, more detailed study will be performed for each system, and research programs for phase II study will be planned. (author)

  18. Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle

    DEFF Research Database (Denmark)

    Treebak, Jonas Thue; Taylor, Eric B.; Witczak, Carol A.

    2010-01-01

    TBC1D4 (also known as AS160) regulates GLUT4 translocation and glucose uptake in adipocytes and skeletal muscle. Its mode of action involves phosphorylation of Serine (S)/Threonine (T) residues by upstream kinases resulting in inactivation of Rab-GAP activity leading to GLUT4 mobilization...

  19. Homozygous TBC1D24 mutation in two siblings with familial infantile myoclonic epilepsy (FIME) and moderate intellectual disability.

    Science.gov (United States)

    Poulat, Anne-Lise; Ville, Dorothée; de Bellescize, Julitta; André-Obadia, Nathalie; Cacciagli, Pierre; Milh, Mathieu; Villard, Laurent; Lesca, Gaetan

    2015-03-01

    Mutations in the TBC1D24 gene were first reported in an Italian family with a unique epileptic phenotype consisting of drug-responsive, early-onset idiopathic myoclonic seizures. Patients presented with isolated bilateral or focal myoclonia, which could evolve to long-lasting attacks without loss of consciousness, with a peculiar reflex component, and were associated with generalized tonic-clonic seizures. This entity was named "familial infantile myoclonic epilepsy" (FIME). More recently, TBC1D24 mutations have been shown to cause a variable range of disorders, including epilepsy of various seizure types and severity, non-syndromic deafness, and DOORS syndrome. We report on the electro-clinical features of two brothers, born to first-cousin parents, affected with infantile-onset myoclonic epilepsy. The peculiar epileptic presentation prompted us to perform direct sequencing of the TBC1D24 gene. The patients had very early onset of focal myoclonic fits with variable topography, lasting a few minutes to several hours, without loss of consciousness, which frequently evolved to generalized myoclonus or myoclonic status. Reflex myoclonia were noticed in one patient. Neurological outcome was marked by moderate intellectual disability. Despite the high frequency of seizures, repeated EEG recordings showed normal background rhythm and rare interictal spikes and waves. We found a homozygous missense mutation, c.457G>A/p.Glu153Lys, in the two affected brothers. This observation combined with recent data from the literature, suggest that mutations in TBCD24 cause a pathological continuum, with FIME at the "benign" end and severe drug-refractory epileptic encephalopathy on the severe end. Early-onset myoclonic epilepsy with focal and generalized myoclonic seizures is a common characteristic of this continuum. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. ANALISIS STRUKTUR MIKRO LAPISAN BOND COAT NIAL THERMAL BARRIER COATING (TBC PADA PADUAN LOGAM BERBASIS CO

    Directory of Open Access Journals (Sweden)

    Toto Sudiro

    2012-11-01

    Full Text Available Kehandalan dan umur pakai sistem Thermal Barrier Coating (TBC ditentukan oleh kestabilan lapisan bond coat dan thermal grown oxide (TGO. Sehingga sangatlah penting untuk memahami mekanisme pembentukan dan degradasi lapisan ini. Pada makalah ini akan dibahas analisis struktur mikro lapisan bond coat NiAl yang dideposisikan pada substrat CoCrNi dengan menggunakan gabungan metoda electroplating dan pack-cementation. Pada makalah ini juga dibahas mekanisme pembentukan void disepanjang interface bond coat¬-substrat setelah tes oksidasi.

  1. Breeder reactor fuel fabrication system development

    International Nuclear Information System (INIS)

    Bennett, D.W.; Fritz, R.L.; McLemore, D.R.; Yatabe, J.M.

    1981-01-01

    Significant progress has been made in the design and development of remotely operated breeder reactor fuel fabrication and support systems (e.g., analytical chemistry). These activities are focused by the Secure Automated Fabrication (SAF) Program sponsored by the Department of Energy to provide: a reliable supply of fuel pins to support US liquid metal cooled breeder reactors and at the same time demonstrate the fabrication of mixed uranium/plutonium fuel by remotely operated and automated methods

  2. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2011-12-31

    This project (10/01/2010-9/30/2013), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This proposal will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. We will develop novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; we will perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; we will perform material characterizations and oxidation/corrosion tests; and we will demonstrate our new Thermal barrier coating (TBC) systems experimentally under Integrated gasification combined cycle (IGCC) environments. The durability of the coating will be examined using the proposed High Temperature/High Pressure Durability Test Rig under real syngas product compositions.

  3. Advanced thermal barrier coatings for operation in high hydrogen content fueled gas turbines.

    Energy Technology Data Exchange (ETDEWEB)

    Sampath, Sanjay [Stony Brook Univ., NY (United States)

    2015-04-02

    The Center for Thermal Spray Research (CTSR) at Stony Brook University in partnership with its industrial Consortium for Thermal Spray Technology is investigating science and technology related to advanced metallic alloy bond coats and ceramic thermal barrier coatings for applications in the hot section of gasified coal-based high hydrogen turbine power systems. In conjunction with our OEM partners (GE and Siemens) and through strategic partnership with Oak Ridge National Laboratory (ORNL) (materials degradation group and high temperature materials laboratory), a systems approach, considering all components of the TBC (multilayer ceramic top coat, metallic bond coat & superalloy substrate) is being taken during multi-layered coating design, process development and subsequent environmental testing. Recent advances in process science and advanced in situ thermal spray coating property measurement enabled within CTSR has been incorporated for full-field enhancement of coating and process reliability. The development of bond coat processing during this program explored various aspects of processing and microstructure and linked them to performance. The determination of the bond coat material was carried out during the initial stages of the program. Based on tests conducted both at Stony Brook University as well as those carried out at ORNL it was determined that the NiCoCrAlYHfSi (Amdry) bond coats had considerable benefits over NiCoCrAlY bond coats. Since the studies were also conducted at different cycling frequencies, thereby addressing an associated need for performance under different loading conditions, the Amdry bond coat was selected as the material of choice going forward in the program. With initial investigations focused on the fabrication of HVOF bond coats and the performance of TBC under furnace cycle tests , several processing strategies were developed. Two-layered HVOF bond coats were developed to render optimal balance of density and surface roughness

  4. Measurement of characteristic to total spectrum ratio of tungsten X-ray spectra for the validation of the modified Tbc model

    International Nuclear Information System (INIS)

    Lopez G, A. H.; Costa, P. R.; Tomal, A.

    2014-08-01

    Primary X-ray spectra were measured in the range of 80 to 150 kV in order to validate a computer program based on a semiempirical model for X-ray spectra evaluation(tbc and mod). The ratio between the characteristic lines and total spectrum was considered for comparing the simulated results and experimental data. The raw spectra measured by the Cd Te detector were corrected by the detector efficiency, Compton effects and characteristic Cd and Te X-rays escape peaks, using a software specifically developed. The software Origin 8.5.1 was used to calculate the spectra and characteristic peaks areas. The obtained result shows that the experimental spectra have higher effective energy than the simulated spectra computed with tbc and mod software. The behavior of the ratio between the characteristic lines and total spectrum for simulated data presents discrepancy with the experimental result. Computed results are in good agreement with theoretical data published by Green, for spectra obtained with 3.04 mm of additional aluminum filtration. The difference of characteristic to total spectrum ratio between experimental and simulated data increases with the tube voltage. (Author)

  5. Measurement of characteristic to total spectrum ratio of tungsten X-ray spectra for the validation of the modified Tbc model

    Energy Technology Data Exchange (ETDEWEB)

    Lopez G, A. H.; Costa, P. R. [University of Sao Paulo, Institute of Physics, Laboratory of Radiation Dosimetry and Medical Physics, Matao Street, alley R, 187, 66318 Sao Paulo (Brazil); Tomal, A., E-mail: ahlopezg@usp.br [Universidade Federal de Goias, Physics Institute, Campus Samambaia, 131 Goiania, Goias (Brazil)

    2014-08-15

    Primary X-ray spectra were measured in the range of 80 to 150 kV in order to validate a computer program based on a semiempirical model for X-ray spectra evaluation(tbc and mod). The ratio between the characteristic lines and total spectrum was considered for comparing the simulated results and experimental data. The raw spectra measured by the Cd Te detector were corrected by the detector efficiency, Compton effects and characteristic Cd and Te X-rays escape peaks, using a software specifically developed. The software Origin 8.5.1 was used to calculate the spectra and characteristic peaks areas. The obtained result shows that the experimental spectra have higher effective energy than the simulated spectra computed with tbc and mod software. The behavior of the ratio between the characteristic lines and total spectrum for simulated data presents discrepancy with the experimental result. Computed results are in good agreement with theoretical data published by Green, for spectra obtained with 3.04 mm of additional aluminum filtration. The difference of characteristic to total spectrum ratio between experimental and simulated data increases with the tube voltage. (Author)

  6. Evaluation of raw milk quality in different production systems and periods of the year

    Directory of Open Access Journals (Sweden)

    Marcos Inácio Marcondes

    2014-12-01

    Full Text Available The objective of this study was to evaluate the quality of raw milk in different production systems and its variation throughout the year. The data were collected from 943 dairy farms in the South, Central-West and Central regions of the state of Minas Gerais, and in Vale do Paraíba, in the state of São Paulo, Brazil. The data were collected in the period from January 2009 to September 2011, in a total of 18,206 samples. The properties were divided into confinement, semi-confinement and extensive production systems. The evaluated factors were somatic cell count (SCC, total bacterial count (TBC and protein and fat contents. There was no effect of production system on the contents of protein, fat and SCC. Total bacterial count, however, was affected by production. Seasonal variations were found for SCC, TBC, protein and fat; the highest protein values were found from March to June; the highest fat contents were obtained from May to August; and TBC and SCC, from December to March. The production system does not interfere with the percentage of fat and protein and SCC of the milk. However, confinement systems present a better TBC content. Both month and year are factors that interfere with TBC, SCC, protein and milk fat, and the best patterns are found in the coldest periods of the year.

  7. Strontium Zirconate TBC Sprayed by a High Feed-Rate Water-Stabilized Plasma Torch

    Science.gov (United States)

    Ctibor, P.; Nevrla, B.; Cizek, J.; Lukac, F.

    2017-12-01

    A novel thermal barrier coating (TBC) material, strontium zirconate SrZrO3, was sprayed by a high feed-rate water-stabilized plasma torch WSP 500. Stainless steel coupons were used as substrates. Coatings with a thickness of about 1.2 mm were produced, whereas the substrates were preheated over 450 °C. The torch worked at 150 kW power and was able to spray SrZrO3 with a high spray rate over 10 kg per hour. Microstructure and microhardness, phase composition, adhesion, thermal conductivity and thermal expansion were evaluated. The coating has low thermal conductivity under 1 W/m K in the interval from room temperature up to 1200 °C. Its crystallite size is slightly over 400 nm and thermal expansion 12.3 µm K-1 in the similar temperature range.

  8. Design and fabrication of the MFTF-B magnet system

    International Nuclear Information System (INIS)

    Tatro, R.E.; Kozman, T.A.

    1985-09-01

    The MFTF-B superconducting magnet system consists of 40 NbTi magnets and two Nb 3 Sn magnets. General Dynamics (GD) designed all magnets except for the small trim coils. GD then fabricated 20 NbTi magnets, while LLNL fabricated 20 NbTi magnets and two Nb 3 Sn magnets. The design phase was completed in February 1984 and included the competitive procurement of magnet structural fabrication, superconductor, G-10CR insulation, support struts and bearings, vapor-cooled leads, and thermal shields for all magnets. Fabrication of all magnets was completed in March 1985. At GD, dual assembly lines were necessary during fabrication in order to meet the aggressive LLNL schedule. The entire magnet system has been installed and aligned at LLNL, and Tech Demo tests will be performed during September-November 1985

  9. Printing technologies in fabrication of drug delivery systems.

    Science.gov (United States)

    Kolakovic, Ruzica; Viitala, Tapani; Ihalainen, Petri; Genina, Natalja; Peltonen, Jouko; Sandler, Niklas

    2013-12-01

    There has been increased activity in the field recently regarding the development and research on various printing techniques in fabrication of dosage forms and drug delivery systems. These technologies may offer benefits and flexibility in manufacturing, potentially paving the way for personalized dosing and tailor-made dosage forms. In this review, the most recent observations and advancements in fabrication of drug delivery systems by utilizing printing technologies are summarized. A general overview of 2D printing techniques is presented including a review of the most recent literature where printing techniques are used in fabrication of drug delivery systems. The future perspectives and possible impacts on formulation strategies, flexible dosing and personalized medication of using printing techniques for fabrication of drug delivery systems are discussed. It is evident that there is an urgent need to meet the challenges of rapidly growing trend of personalization of medicines through development of flexible drug-manufacturing approaches. In this context, various printing technologies, such as inkjet and flexography, can play an important role. Challenges on different levels exist and include: i) technological development of printers and production lines; ii) printable formulations and carrier substrates; iii) quality control and characterization; and iv) regulatory perspectives.

  10. Fabrication Of Control Rod System Of The RSG-GAS

    International Nuclear Information System (INIS)

    Sudirdjo, Hari; Setyono; Prasetya, Hendra

    2001-01-01

    Eight units of control rod mechanical system of RSG-GAS has been fabricated. The control rod mechanical system of RSG-GAS consist of guide tube and lifting rod. Complete construction of the control rod mechanical system of RSG-GAS are guide tube, lifting rod, absorber, and absorber casing. The eight units of the control rod mechanical system of RSG-GAS has been fabricated according to the mechanical engineering design

  11. Failure mechanism for thermal fatigue of thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Giolli, C.; Scrivani, A.; Rizzi, G. [Turbocoating S.p.A., Rubbiano di Solignano (Italy); Borgioli, F. [Firenze Univ., Sesto Fiorentino (Italy); Bolelli, G.; Lusvarghi, L. [Univ. di Modena e Reggio Emilia, Modena (Italy)

    2008-07-01

    High temperature thermal fatigue causes the failure of Thermal Barrier Coating (TBC) systems. Due to the difference in thickness and microstructure between thick TBCs and traditional thin TBCs, they cannot be assumed a-priori to possess the same failure mechanisms. Thick TBCs, consisting of a CoNiCrAlY bond coat and Yttria Partially Stabilised Zirconia top coat with different values of porosity, were produced by Air Plasma Spray. Thermal fatigue resistance limit of TBCs was tested by Furnace Cycling Tests (FCT) according to the specifications of an Original Equipment Manufacturer (OEM). TBC systems were analyzed before and after FCT. The morphological and chemical evolution of CoNiCrAlY/TGO microstructure was studied. Sintering effect, residual stress, phase transformation and fracture toughness were evaluated in the ceramic Top Coat. All the tested samples passed FCT according to the specification of an important OEM. Thermal fatigue resistance increases with the amount of porosity in the top coat. The compressive in-plane stresses increase in the TBC systems after thermal cycling, nevertheless the increasing rate has a trend contrary to the porosity level of top coat. The data suggest that the spallation happens at the TGO/Top Coat interface. The failure mechanism of thick TBCs subjected to thermal fatigue was eventually found to be similar to the failure mechanism of thin TBC systems made by APS. (orig.)

  12. Characterization of the Materials Synthesized by High Pressure-High Temperature Treatment of a Polymer Derived t-BC2N Ceramic

    OpenAIRE

    Matizamhuka, Wallace R.; Sigalas, Iakovos; Herrmann, Mathias; Dubronvinsky, Leonid; Dubrovinskaia, Natalia; Miyajima, Nobuyoshi; Mera, Gabriela; Riedel, Ralf

    2011-01-01

    Bulk B-C-N materials were synthesized under static high thermobaric conditions (20 GPa and 2,000 °C) in a multianvil apparatus from a polymer derived t-BC1.97N ceramic. The bulk samples were characterised using X-ray synchrotron radiation and analytical transmission electron microscopy in combination with electron energy loss spectroscopy. Polycrystalline B-C-N materials with a cubic type structure were formed under the applied reaction conditions, but the formation of a ternary cubic diamond...

  13. Residual stress distribution analysis of heat treated APS TBC using image based modelling.

    Science.gov (United States)

    Li, Chun; Zhang, Xun; Chen, Ying; Carr, James; Jacques, Simon; Behnsen, Julia; di Michiel, Marco; Xiao, Ping; Cernik, Robert

    2017-08-01

    We carried out a residual stress distribution analysis in a APS TBC throughout the depth of the coatings. The samples were heat treated at 1150 °C for 190 h and the data analysis used image based modelling based on the real 3D images measured by Computed Tomography (CT). The stress distribution in several 2D slices from the 3D model is included in this paper as well as the stress distribution along several paths shown on the slices. Our analysis can explain the occurrence of the "jump" features near the interface between the top coat and the bond coat. These features in the residual stress distribution trend were measured (as a function of depth) by high-energy synchrotron XRD (as shown in our related research article entitled 'Understanding the Residual Stress Distribution through the Thickness of Atmosphere Plasma Sprayed (APS) Thermal Barrier Coatings (TBCs) by high energy Synchrotron XRD; Digital Image Correlation (DIC) and Image Based Modelling') (Li et al., 2017) [1].

  14. Characterization of the Materials Synthesized by High Pressure-High Temperature Treatment of a Polymer Derived t-BC2N Ceramic

    Directory of Open Access Journals (Sweden)

    Gabriela Mera

    2011-11-01

    Full Text Available Bulk B-C-N materials were synthesized under static high thermobaric conditions (20 GPa and 2,000 °C in a multianvil apparatus from a polymer derived t-BC1.97N ceramic. The bulk samples were characterised using X-ray synchrotron radiation and analytical transmission electron microscopy in combination with electron energy loss spectroscopy. Polycrystalline B-C-N materials with a cubic type structure were formed under the applied reaction conditions, but the formation of a ternary cubic diamond-like c-BC2N compound, could not be unambiguously confirmed.

  15. Characterization of the Materials Synthesized by High Pressure-High Temperature Treatment of a Polymer Derived t-BC2N Ceramic

    Science.gov (United States)

    Matizamhuka, Wallace R.; Sigalas, Iakovos; Herrmann, Mathias; Dubronvinsky, Leonid; Dubrovinskaia, Natalia; Miyajima, Nobuyoshi; Mera, Gabriela; Riedel, Ralf

    2011-01-01

    Bulk B-C-N materials were synthesized under static high thermobaric conditions (20 GPa and 2,000 °C) in a multianvil apparatus from a polymer derived t-BC1.97N ceramic. The bulk samples were characterised using X-ray synchrotron radiation and analytical transmission electron microscopy in combination with electron energy loss spectroscopy. Polycrystalline B-C-N materials with a cubic type structure were formed under the applied reaction conditions, but the formation of a ternary cubic diamond-like c-BC2N compound, could not be unambiguously confirmed. PMID:28824124

  16. Schottky barrier MOSFET systems and fabrication thereof

    Science.gov (United States)

    Welch, J.D.

    1997-09-02

    (MOS) device systems-utilizing Schottky barrier source and drain to channel region junctions are disclosed. Experimentally derived results which demonstrate operation of fabricated N-channel and P-channel Schottky barrier (MOSFET) devices, and of fabricated single devices with operational characteristics similar to (CMOS) and to a non-latching (SRC) are reported. Use of essentially non-rectifying Schottky barriers in (MOS) structures involving highly doped and the like and intrinsic semiconductor to allow non-rectifying interconnection of, and electrical accessing of device regions is also disclosed. Insulator effected low leakage current device geometries and fabrication procedures therefore are taught. Selective electrical interconnection of drain to drain, source to drain, or source to source, of N-channel and/or P-channel Schottky barrier (MOSFET) devices formed on P-type, N-type and Intrinsic semiconductor allows realization of Schottky Barrier (CMOS), (MOSFET) with (MOSFET) load, balanced differential (MOSFET) device systems and inverting and non-inverting single devices with operating characteristics similar to (CMOS), which devices can be utilized in modulation, as well as in voltage controlled switching and effecting a direction of rectification. 89 figs.

  17. A wearable 12-lead ECG acquisition system with fabric electrodes.

    Science.gov (United States)

    Haoshi Zhang; Lan Tian; Huiyang Lu; Ming Zhou; Haiqing Zou; Peng Fang; Fuan Yao; Guanglin Li

    2017-07-01

    Continuous electrocardiogram (ECG) monitoring is significant for prevention of heart disease and is becoming an important part of personal and family health care. In most of the existing wearable solutions, conventional metal sensors and corresponding chips are simply integrated into clothes and usually could only collect few leads of ECG signals that could not provide enough information for diagnosis of cardiac diseases such as arrhythmia and myocardial ischemia. In this study, a wearable 12-lead ECG acquisition system with fabric electrodes was developed and could simultaneously process 12 leads of ECG signals. By integrating the fabric electrodes into a T-shirt, the wearable system would provide a comfortable and convenient user interface for ECG recording. For comparison, the proposed fabric electrode and the gelled traditional metal electrodes were used to collect ECG signals on a subject, respectively. The approximate entropy (ApEn) of ECG signals from both types of electrodes were calculated. The experimental results show that the fabric electrodes could achieve similar performance as the gelled metal electrodes. This preliminary work has demonstrated that the developed ECG system with fabric electrodes could be utilized for wearable health management and telemedicine applications.

  18. Secure Automated Fabrication: a system design description (SDD), section 1

    International Nuclear Information System (INIS)

    Konze, G.M.; Thompson, M.L.; Wadekamper, D.C.; Zimmer, J.J.

    Information is presented concerning the conversion system to convert purified mixed nitrate solution to MO/sub x/ powder; powder preparation and pellet fabrication; sintering and pin loading; assembly fabrication; and scrap recovery

  19. Measurement of interfacial shear mechanical properties in thermal barrier coating systems by a barb pullout method

    International Nuclear Information System (INIS)

    Guo, S.Q.; Mumm, D.R.; Karlsson, A.M.; Kagawa, Y.

    2005-01-01

    A test technique has been developed to facilitate evaluation of the fracture characteristics of coatings and interfaces in thermal barrier coating (TBC) systems. The methodology has particular application in analyzing delamination crack growth, where crack propagation occurs under predominantly mode II loading. The technique has been demonstrated by quantitatively measuring the effective delamination fracture resistance of an electron-beam physical vapor deposition TBC

  20. Methods and systems for fabricating high quality superconducting tapes

    Science.gov (United States)

    Majkic, Goran; Selvamanickam, Venkat

    2018-02-13

    An MOCVD system fabricates high quality superconductor tapes with variable thicknesses. The MOCVD system can include a gas flow chamber between two parallel channels in a housing. A substrate tape is heated and then passed through the MOCVD housing such that the gas flow is perpendicular to the tape's surface. Precursors are injected into the gas flow for deposition on the substrate tape. In this way, superconductor tapes can be fabricated with variable thicknesses, uniform precursor deposition, and high critical current densities.

  1. Methods and systems for fabricating high quality superconducting tapes

    Energy Technology Data Exchange (ETDEWEB)

    Majkic, Goran; Selvamanickam, Venkat

    2018-02-13

    An MOCVD system fabricates high quality superconductor tapes with variable thicknesses. The MOCVD system can include a gas flow chamber between two parallel channels in a housing. A substrate tape is heated and then passed through the MOCVD housing such that the gas flow is perpendicular to the tape's surface. Precursors are injected into the gas flow for deposition on the substrate tape. In this way, superconductor tapes can be fabricated with variable thicknesses, uniform precursor deposition, and high critical current densities.

  2. A chromia forming thermal barrier coating system

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, M.P.; Evans, H.E. [Metallurgy and Materials, The University of Birmingham, Birmingham, B15 2TT (United Kingdom); Gray, S.; Nicholls, J.R. [Surface Science and Engineering Centre, Cranfield University, Cranfield, MK43 0AL (United Kingdom)

    2011-07-15

    Conventional thermal barrier coating (TBC) systems consist of an insulating ceramic topcoat, a bond coat for oxidation protection and the underlying superalloy designed to combat the oxidising conditions in aero- and land-based gas turbines. Under high-temperature oxidation, the use of an alumina forming bond coat is warranted, thus all current TBC systems are optimised for the early formation of a dense, protective thermally grown oxide (TGO) of alumina. This also offers protection against Type I hot corrosion but a chromia layer gives better protection against Type II corrosion and intermediate temperatures, the conditions found in land-based gas turbines. In this paper the authors present the first known results for a chromia forming TBC system. Tests have been performed under oxidising conditions, up to 1000 h, at temperatures between 750 C and 900 C, and under Type I (900 C) and Type II (700 C) hot corrosion conditions up to 500 h. Under all these conditions no cracking, spallation or degradation was observed. Examination showed the formation of an adherent, dense chromia TGO at the bond coat / topcoat interface. These initial results are very encouraging and the TGO thicknesses agree well with comparable results reported in the literature. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Zirconia based ceramic coating on a metal with plasma electrolytic oxidation

    Science.gov (United States)

    Akatsu, T.; Kato, T.; Shinoda, Y.; Wakai, F.

    2011-10-01

    We challenge to fabricate a thermal barrier coating (TBC) made of ZrO2 based ceramics on a Ni based single crystal superalloy with plasma electrolytic oxidation (PEO) by incorporating metal species from electrolyte into the coating. The PEO process is carried out on the superalloy galvanized with aluminium for 15min in Na4O7P4 solution for an oxygen barrier coating (OBC) and is followed by PEO in K2[Zr(CO3)2(OH)2] solution for TBC. We obtained the following results; (1) Monoclinic-, tetragonal-, cubic-ZrO2 crystals were detected in TBC. (2) High porosity with large pores was observed near the interface between OBC and TBC. The fine grain structure with a grain size of about 300nm was typically observed. (3) The adhesion strength between PEO coatings and substrate was evaluated to be 26.8±6.6MPa. At the adhesion strength test, PEO coatings fractured around the interface between OBC and TBC. The effect of coating structure on adhesion strength is explained through the change in spark discharge during PEO process.

  4. Fuel fabrication instrumentation and control system overview

    International Nuclear Information System (INIS)

    Bennett, D.W.; Fritz, R.L.

    1980-10-01

    A process instrumentation and control system is being developed for automated fabrication of breeder reactor fuel at the Hanford Engineering Development Laboratory (HEDL) in Richland, Washington. The basic elements of the control system are a centralized computer system linked to distributed local computers, which direct individual process applications. The control philosophy developed for the equipment automation program stresses system flexibility and inherent levels of redundant control capabilities. Four different control points have been developed for each unit process operation

  5. Reliability of a treatment-based classification system for subgrouping people with low back pain.

    Science.gov (United States)

    Henry, Sharon M; Fritz, Julie M; Trombley, Andrea R; Bunn, Janice Y

    2012-09-01

    Observational, cross-sectional reliability study. To examine the interrater reliability of novice raters in their use of the treatment-based classification (TBC) system for low back pain and to explore the patterns of disagreement in classification errors. Although the interrater reliability of individual test items in the TBC system is moderate to good, some error persists in classification decision making. Understanding which classification errors are common could direct further refinement of the TBC system. Using previously recorded patient data (n = 24), 12 novice raters classified patients according to the TBC schema. These classification results were combined with those of 7 other raters, allowing examination of the overall agreement using the kappa statistic, as well as agreement/disagreement among pairwise comparisons in classification assignments. A chi-square test examined differences in percent agreement between the novice and more experienced raters and differences in classification distributions between these 2 groups of raters. Among 12 novice raters, there was 80.9% agreement in the pairs of classification (κ = 0.62; 95% confidence interval: 0.59, 0.65) and an overall 75.5% agreement (κ = 0.57; 95% confidence interval: 0.55, 0.69) for the combined data set. Raters were least likely to agree on a classification of stabilization (77.5% agreement). The overall percentage of pairwise classification judgments that disagreed was 24.5%, with the most common disagreement being between manipulation and stabilization (11.0%), followed by a mismatch between stabilization and specific exercise (8.2%). Additional refinement is needed to reduce rater disagreement that persists in the TBC decision-making algorithm, particularly in the stabilization category. J Orthop Sports Phys Ther 2012;42(9):797-805, Epub 7 June 2012. doi:10.2519/jospt.2012.4078.

  6. Secure automated fabrication (SAF). Phase I interim report: a systems analysis

    International Nuclear Information System (INIS)

    1979-01-01

    An advanced Secure Automated Fabrication (SAF) System is being developed for mixed uranium and plutonium fuel fabrication. SAF System development will ultimately result in systems which maximize personnel radiation protection, restrict and control access to SNM material, improve containment and detection systems for nuclear materials, provide adequate SNM accountability and improve product uniformity and quality. A systems requirement analysis study was initiated to establish the consistent and objective set of requirements within which the choice among alternatives represents the balanced viewpoints of performance, achievability and risk

  7. Design and fabrication of self-powered micro-harvesters rotating and vibrated micro-power systems

    CERN Document Server

    Pan, C T; Lin, Liwei; Chen, Ying-Chung

    2013-01-01

    Presents the latest methods for designing and fabricating self-powered micro-generators and energy harvester systems Design and Fabrication of Self-Powered Micro-Harvesters introduces the latest trends of self-powered generators and energy harvester systems, including the design, analysis and fabrication of micro power systems. Presented in four distinct parts, the authors explore the design and fabrication of: vibration-induced electromagnetic micro-generators; rotary electromagnetic micro-generators; flexible piezo-micro-generator with various widths; and PVDF electrospunpiezo-energy with

  8. Fabrication of control rod system of RSG-GAS

    International Nuclear Information System (INIS)

    Hari-Sudirdjo; Setyono; Hendra-Prasetya

    2003-01-01

    Two unit absorbers, they are part of RSG-GAS control rod system, have been fabricated. One set absorber consist of two absorber plates and absorber casing. Absorber plate is made of Ag In Cd ( 80%, 15%, 5% ) alloy, which is cladded by stainless steel plate SS-316. Ag In Cd absorber plate has size of 625 mm x 60 mm x 3.3 mm, while cladding plat has thickness of 0.8 mm. Fabrication of two set absorbers has been conducted according to the plan

  9. Fabrication of samarium strontium aluminate ceramic and deposition of thermal barrier coatings by air plasma spray process

    Directory of Open Access Journals (Sweden)

    Baskaran T

    2018-01-01

    Full Text Available Thermal barrier coatings (TBC with the metallic NiCrAlY bond coat are often used in many aircraft engines to protect superalloy components from high-temperature corrosion thereby to improve the life of gas turbine components. The search for new TBC material has been intensified in recent years due to lack of thermo-physical properties of conventionally used Yttria stabilized Zirconia (YSZ TBCs. Recently, the rare earth containing Samarium Strontium Aluminate (SSA based ceramic was proposed as a new TBC material due to its matching thermo-physical properties with the substrate. The present work focused on the synthesis of SSA ceramics for TBCs application and its coatings development on Ni-based superalloy Inconel 718 substrate by air plasma spray process. The X-ray photoelectron spectroscopy (XPS result confirmed the formation of single phase SSA ceramic after synthesis. The surface morphology of SSA TBCs is mainly composed of melted splats, semi and un-melted particles. The cross-sectional SEM micrographs did not show any spallation at the interface which indicated good mechanical interlocking between the bond coat and ceramic top coat. The Young’s modulus and hardness of SSA TBCs were found to be 80 and 6.1 GPa, respectively. The load-depth curve of SSA TBC showed good elastic recovery about 47 %.

  10. Design of a quality assurance system in the nuclear fuel fabrication

    International Nuclear Information System (INIS)

    Garcia Rojas Palacios, L.

    1992-01-01

    A)For the first time a project on nuclear fuel fabrication is going to be lead in this country. For this reason the work is oriented to establish a quality assurance system for the different stages of fuel fabrication. C) The work of this thesis was developed first by means of an analysis of quality philosophies of Deming, Ishikawa, Juran and Crosby from which several important points were stracted to be used in the designed quality system. Metrology and normalization are so important for quality control that a study of them is made considering definitions, unit systems and type of errors (for Metrology) as well as standards for quality systems, qualification, destructive and non destructive tests, shipment, packing for nuclear power plants. With the standards as a basis, the working strategy for the system was reached, as well as the design of control cards and the design of documents for inspection control, personnel and its documentation and finally the diagrams for each one of the fabrication stages

  11. Fundamentals and advances in the development of remote welding fabrication systems

    Science.gov (United States)

    Agapakis, J. E.; Masubuchi, K.; Von Alt, C.

    1986-01-01

    Operational and man-machine issues for welding underwater, in outer space, and at other remote sites are investigated, and recent process developments are described. Probable remote welding missions are classified, and the essential characteristics of fundamental remote welding tasks are analyzed. Various possible operational modes for remote welding fabrication are identified, and appropriate roles for humans and machines are suggested. Human operator performance in remote welding fabrication tasks is discussed, and recent advances in the development of remote welding systems are described, including packaged welding systems, stud welding systems, remotely operated welding systems, and vision-aided remote robotic welding and autonomous welding systems.

  12. A Conduction-Cooled Superconducting Magnet System-Design, Fabrication and Thermal Tests

    DEFF Research Database (Denmark)

    Song, Xiaowei (Andy); Holbøll, Joachim; Wang, Qiuliang

    2015-01-01

    A conduction-cooled superconducting magnet system with an operating current of 105.5 A was designed, fabricated and tested for material processing applications. The magnet consists of two coaxial NbTi solenoid coils with an identical vertical height of 300 mm and is installed in a high-vacuumed c......A conduction-cooled superconducting magnet system with an operating current of 105.5 A was designed, fabricated and tested for material processing applications. The magnet consists of two coaxial NbTi solenoid coils with an identical vertical height of 300 mm and is installed in a high......-vacuumed cryostat. A two-stage GM cryocooler with a cooling power of 1.5 W at 4.2 K in the second stage is used to cool the system from room temperature to 4.2 K. In this paper, the detailed design, fabrication, thermal analysis and tests of the system are presented....

  13. Materials and fabrication requirements for APWR systems

    International Nuclear Information System (INIS)

    Boothby, R.M.; Hippsley, C.A.; Gorton, O.K.; Garwood, S.J.

    1995-01-01

    Materials specifications for advanced pressurized water-cooled reactor (APWR) systems are generally based on existing designs, with improved materials and fabrication procedures being developed to counter known degradation effects. In this paper, materials ageing and degradation mechanisms in PWR primary circuit pressure boundary components (i.e. the reactor pressure vessel (RPV), control rod drive mechanisms (CRDMs), coolant piping, coolant pump casing, pressurizer, and steam generators) are reviewed. Important degradation mechanisms include irradiation embrittlement of the RPV, thermal ageing embrittlement of ferritic (e.g. the pressurizer) and cast austenitic (e.g. coolant pump casing and pipe elbows) steel components and environmentally assisted cracking of steam generator tubing and CRDM penetrations. Improved materials specifications and component design and fabrication issues affecting the integrity of the pressure boundary are discussed in the light of these materials problems. Improved fabrication procedures adopted for Sizewell B, such as the utilization of ring forgings to eliminate axial welds in the RPV and steam generator shells and the use of one-piece castings for coolant pump casings, provide a benchmark against which other APWR designs may be judged. (author)

  14. Applications of the models of Archer and TBC in the determination of thickness of barriers for radiological rooms

    International Nuclear Information System (INIS)

    Costa, Paulo R.; Salvador, F.C.; Nersissian, D.Y.; Caldas, L.V.E.

    2005-01-01

    TBC models for simulation of X-ray spectra and Archer for the determination of attenuation properties of materials have been applied according to the methodology set out in the publication NCRP 147 for obtaining radiological rooms protective barriers. The methodology used information from a survey of actual workload distributions of radiological rooms of the city of Sao Paulo, SP, Brazil as well as a similar survey conducted in the United States. The results of the application of the methodology demonstrate the possibility of reduction of barriers necessary for the protection of radiological rooms when compared to the direct application of the NCRP 147. The method developed serves both for estimation of shielding requirements in radiological rooms using up-to-date methodologies, as well as for training of professionals for design of shields

  15. Manufacturing routes for disposable polymer blood diagnostic microfluidic systems

    DEFF Research Database (Denmark)

    Tosello, Guido; Griffiths, Christian; Azcarate, Sabino

    2008-01-01

    (Multi-Material Micro Manufacture) that are relevant to the technology for disposable polymer parts for Micro-Tele-BioChip (µTBC) medical platforms. Combining two separation mechanisms a novel micro channel design was developed. The separation unit is based on a micro channel bend structure where typical...... channel dimensions are 20 µm for the plasma channel width, and 50-75 µm for the cell channel. The height of all channels is 100 µm. The micro channel bend works simply on physical and hydrodynamic separation mechanisms without integrated actuators like pumps or valves. For the mass-fabrication of low...

  16. Polymorphous computing fabric

    Science.gov (United States)

    Wolinski, Christophe Czeslaw [Los Alamos, NM; Gokhale, Maya B [Los Alamos, NM; McCabe, Kevin Peter [Los Alamos, NM

    2011-01-18

    Fabric-based computing systems and methods are disclosed. A fabric-based computing system can include a polymorphous computing fabric that can be customized on a per application basis and a host processor in communication with said polymorphous computing fabric. The polymorphous computing fabric includes a cellular architecture that can be highly parameterized to enable a customized synthesis of fabric instances for a variety of enhanced application performances thereof. A global memory concept can also be included that provides the host processor random access to all variables and instructions associated with the polymorphous computing fabric.

  17. Simulation and fabrication of integrated polystyrene microlens in microfluidic system

    KAUST Repository

    Fan, Yiqiang

    2013-05-17

    This paper presents a simple and quick method to integrate microlens with the microfluidics systems. The polystyrene (PS) based microlens is fabricated with the free surface thermal compression molding methods, a thin PS sheet with the microlens is bonded to a PMMA substrate which contains the laser ablated microchannels. The convex profiler of the microlens will give a magnified images of the microchannels for easier observation. Optical simulation software is being used for the design and simulation of the microlens to have optimal optical performance with the desired focal length. A microfluidic system with the integrated PS microlens is also fabricated for demonstration.

  18. Simulation and fabrication of integrated polystyrene microlens in microfluidic system

    KAUST Repository

    Fan, Yiqiang; Li, Huawei; Conchouso Gonzalez, David; Foulds, Ian G.

    2013-01-01

    This paper presents a simple and quick method to integrate microlens with the microfluidics systems. The polystyrene (PS) based microlens is fabricated with the free surface thermal compression molding methods, a thin PS sheet with the microlens is bonded to a PMMA substrate which contains the laser ablated microchannels. The convex profiler of the microlens will give a magnified images of the microchannels for easier observation. Optical simulation software is being used for the design and simulation of the microlens to have optimal optical performance with the desired focal length. A microfluidic system with the integrated PS microlens is also fabricated for demonstration.

  19. PEDOT pillar fabrication using DOD inkjet system

    Science.gov (United States)

    Cui, Wei; Chang, Cheng-Ling; Wang, Wei-Chih

    2012-04-01

    In this paper, we present our preliminary results of high aspect ratio 3D PEDOT pillar study by drop-on demand (DOD) direct printing system. Design of the experimental setup and the fabrication of the DOD PEDOT pillar are introduced. Currently, the system can achieve a PEDOT pillar with a height of 300 μm and 80 μm in diameter. The proposed PEDOT 3D printing process has a wide range of potential applications in the eletronics and display industry.

  20. Pengaruh komposisi komposit al2o3/ysz dan variasi feed rate terhadap ketahanan termal dan kekuatan lekat pada Ysz-al2o3/ysz double layer tbc

    Directory of Open Access Journals (Sweden)

    Parindra Kusriantoko

    2014-03-01

    Full Text Available TBC (Thermal Barrier Coating dengan YSZ-Al2O3/YSZ top coat (TCdan MCrAlY sebagai bond coat (BC yang selanjutnya disebut sebagai YSZ-Al2O3/YSZ double layer TBC dibuat dengan menggunakan metode flame spray.Hasil pelapisan sebelum dan sesudah diuji termal dikarakterisasi menggunakan SEM, EDX dan XRD.Dari hasil penelitian didapatkan bahwa semakin tinggi powder feed rate akan berpengaruh pada morfologi permukaan lapisan. Feed rate makin rendah menyebabkan struktur yang cenderung kasar dan tidak padat dan cenderung berporos. Lapisan komposit Al2O3/YSZ juga sangat berpengaruh pada pertumbuhan TGO (Thermally Grown Oxide setelah dilakukan uji termal, dimana komposisi paling bagus dengan pertumbuhan TGO paling rendah adalah 15%Al2O3/8YSZ. Hasil pengujian TGA menunjukkan semua sampel mulai teroksidasi pada temperatur 1000-1030oC dan didapatkan sampel paling stabil adalah 15% Al2O3/8YSZ 14 dan 20 gr/min. Dari pengujian XRD sampel yang memiliki fasa yang paling stabil adalah 15%Al2O3/8YSZ dengan fasa t-ZrO2 dan m-ZrO2. Dari pengujian Thermal Torch dan Pull Off komposisi 15%Al2O3/8YSZjuga memiliki ketahanan terhadap pengerusakan yang paling baik dan kelekatan yang baik sebesar 10 MPa.

  1. Systems and methods for large-scale nanotemplate and nanowire fabrication

    KAUST Repository

    Vidal, Enrique Vilanova; Alfadhel, Ahmed; Ivanov, Iurii; Kosel, Jü rgen

    2016-01-01

    Systems and methods for largescale nanotemplate and nanowire fabrication are provided. The system can include a sample holder and one or more chemical containers fluidly connected to the sample holder. The sample holder can be configured to contain

  2. Printing technologies in fabrication of drug delivery systems

    DEFF Research Database (Denmark)

    Kolakovic, Ruzica; Viitala, Tapani; Ihalainen, Petri

    2013-01-01

    INTRODUCTION: There has been increased activity in the field recently regarding the development and research on various printing techniques in fabrication of dosage forms and drug delivery systems. These technologies may offer benefits and flexibility in manufacturing, potentially paving the way...... for personalized dosing and tailor-made dosage forms.\

  3. Fabrication of mechanical system of the FPM capsule puller

    International Nuclear Information System (INIS)

    Sudirdjo, Hari; Prasetya, Hendra

    2000-01-01

    A mechanical system of the FPM capsule puller has been fabricated, which has a function to pull the irradiated FPM capsule. The construction of the system consist of driving motor equipped with reduction gear, spindle, and puller wire. The system has puller stroke of 700 mm, therefore the puller will be terminated at the outside of the reactor core. A function test had been done and shows that the system has fulfilled the requirements

  4. New system for wiggler fabrication and testing

    International Nuclear Information System (INIS)

    Warren, R.W.; Elliott, C.J.

    1988-01-01

    A system approach is taken for fabrication and testing of wigglers for free-electron lasers. Emphasis is placed on convenient, practical, assembly procedures that produce wigglers with high fields, two-plane focusing, and facilities for in-place adjustments. Equal emphasis is placed on rapid and precise techniques for measuring field errors, both before final assembly and afterward, during wiggler operation. (author). 10 refs, 12 figs

  5. High-speed micro electrode tool fabrication by a twin-wire EDM system

    International Nuclear Information System (INIS)

    Sheu, Dong-Yea

    2008-01-01

    This paper describes a new machining process which combines twin-electro-wire together with two electro discharge circuits to rapidly fabricate micro electrode tools. The results show that transistor electro discharge and RC electro discharge circuits coexist to fabricate micro tools with rough and finish machining both on the same machine. Compared to conventional wire electro discharge grinding (WEDG) technology, a twin-wire EDM system that combines rough and finish machining into one process allows the efficient fabrication of micro tools. This high-speed micro tool fabrication process can be applied not only to micro electrode machining but also to micro punching tool and micro probing tips machining

  6. Improved Thermally Grown Oxide Scale in Air Plasma Sprayed NiCrAlY/Nano-YSZ Coatings

    International Nuclear Information System (INIS)

    Daroonparvar, M.; Yajid, M.A.M.; Yusof, N.M.; Hussain, M.S.

    2013-01-01

    Oxidation has been considered as one of the principal disruptive factors in thermal barrier coating systems during service. So, oxidation behavior of thermal barrier coating (TBC) systems with nano structured and micro structured YSZ coatings was investigated at 1000 degree c for 24 h, 48 h, and 120 h. Air plasma sprayed nano-YSZ coating exhibited a tri modal structure. Microstructural characterization also demonstrated an improved thermally grown oxide scale containing lower spinels in nano-TBC system after 120 h of oxidation. This phenomenon is mainly related to the unique structure of the nano-YSZ coating, which acted as a strong barrier for oxygen diffusion into the TBC system at elevated temperatures. Nearly continues but thinner Al 2 O 3 layer formation at the NiCrAlY/nano-YSZ interface was seen, due to lower oxygen infiltration into the system. Under this condition, spinels formation and growth on the Al 2 O 3 oxide scale were diminished in nano-TBC system compared to normal TBC system.

  7. Zero risk fuel fabrication: a systems analysis

    International Nuclear Information System (INIS)

    1979-01-01

    Zero risk is a concept used to ensure that system requirements are developed through a systems approach such that the choice(s) among alternatives represents the balanced viewpoints of performance, achievability and risk. Requirements to ensure characteristics such as stringent accountability, low personnel exposure and etc. are needed to guide the development of component and subsystems for future LMFBR fuel supply systems. To establish a consistent and objective set of requirements, RF and M-TMC has initiated a systems requirements analysis activity. This activity pivots on judgement and experience provided by a Task Force representing industrial companies engaged in fuel fabrication in licensed facilities. The Task Force members are listed in Appendix A. Input developed by this group is presented as a starting point for the systems requirements analysis

  8. Design study and evaluation of fuel fabrication systems for FR fuel cycle

    International Nuclear Information System (INIS)

    Namekawa, Takashi; Tanaka, Kenya; Kawaguchi, Koichi; Koike, Kazuhiro; Shimuta, Hiroshi; Suzuki, Yoshihiro

    2004-01-01

    The plant concept for each FBR fuel fabrication system has been constructed and evaluated, which achieves economical improvement, decrease in the environmental burden, better resource utilization, and proliferation resistance by the various innovative techniques employed. The results are as follows: (1) For oxide fuels, the simplified pelletizing method has a high technical feasibility, and it is possible to apply this method to practical process at early stage, because this method is based on wealth results of a conventional method. (2) For oxide fuels, the sphere packing fuel fabrication system by gelation and vibro-compaction processes has the advantage of lesser dispersion of the fine powder due to the use of solution and granule in the process. However this system shoulders additional cost for the liquid waste treatment process to dispose a large bulk of process liquid waste. (3) For the metal fuel, the casting system is generally expected to have high economical efficiency even for small-scale facilities, although verification for fabrication of the TRU alloy slug is required. (author)

  9. High efficiency pump combiner fabricated by CO2 laser splicing system

    Science.gov (United States)

    Zhu, Gongwen

    2018-02-01

    High power combiners are of great interest for high power fiber lasers and fiber amplifiers. With the advent of CO2 laser splicing system, power combiners are made possible with low manufacturing cost, low loss, high reliability and high performance. Traditionally fiber optical components are fabricated with flame torch, electrode arc discharge or filament heater. However, these methods can easily leave contamination on the fiber, resulting inconsistent performance or even catching fire in high power operations. The electrodes or filaments also degrade rapidly during the combiner manufacturing process. The rapid degradation will lead to extensive maintenance, making it unpractical or uneconomic for volume production. By contrast, CO2 laser is the cleanest heating source which provides reliable and repeatable process for fabricating fiber optic components including high power combiners. In this paper we present an all fiber end pumped 7x1 pump combiner fabricated by CO2 laser splicing system. The input pump fibers are 105/125 (core/clad diameters in μm) fibers with a core NA of 0.22. The output fiber is a 300/320 fiber with a core NA of 0.22. The average efficiency is 99.4% with all 7 ports more than 99%. The process is contamination-free and highly repeatable. To our best knowledge, this is the first report in the literature on power combiners fabricated by CO2 laser splicing system. It also has the highest reported efficiency of its kind.

  10. Estimates of Canadian fuel fabrication costs for alternative fuel cycles and systems

    International Nuclear Information System (INIS)

    Blahnik, C.

    1979-04-01

    Unit fuel fabrication costs are estimated for alternate fuel cycles and systems that may be of interest in Ontario Hydro's strategy analyses. A method is proposed for deriving the unit fuel fabrication price to be paid by a Canadian utility as a function of time (i.e. the price that reflects the changing demand/supply situation in the particular scenario considered). (auth)

  11. Fabrication of silicon strip detectors using a step-and-repeat lithography system

    International Nuclear Information System (INIS)

    Holland, S.

    1991-11-01

    In this work we describe the use of a step-and-repeat lithography system (stepper) for the fabrication of silicon strip detectors. Although the field size of the stepper is only 20 mm in diameter, we have fabricated much larger detectors by printing a repetitive strip detector pattern in a step-and-repeat fashion. The basic unit cell is 7 mm in length. The stepper employs a laser interferometer for stage placement, and the resulting high precision allows one to accurately place the repetitive patterns on the wafer. A small overlap between the patterns ensures a continuous strip. A detector consisting of 512 strips on a 50 μm pitch has been fabricated using this technique. The dimensions of the detector are 6.3 cm by 2.56 cm. Yields of over 99% have been achieved, where yield is defined as the percentage of strips with reverse leakage current below 1 nA. In addition to the inherent advantages of a step-and-repeat system, this technique offers great flexibility in the fabrication of large-area strip detectors since the length and width of the detector can be changed by simply reprogramming the stepper computer. Hence various geometry strip detectors can be fabricated with only one set of masks, as opposed to a separate set of masks for each geometry as would be required with a contact or proximity aligner

  12. Novel Nano-Materials and Nano-Fabrication Techniques for Flexible Electronic Systems

    Directory of Open Access Journals (Sweden)

    Kyowon Kang

    2018-05-01

    Full Text Available Recent progress in fabricating flexible electronics has been significantly developed because of the increased interest in flexible electronics, which can be applied to enormous fields, not only conventional in electronic devices, but also in bio/eco-electronic devices. Flexible electronics can be applied to a wide range of fields, such as flexible displays, flexible power storages, flexible solar cells, wearable electronics, and healthcare monitoring devices. Recently, flexible electronics have been attached to the skin and have even been implanted into the human body for monitoring biosignals and for treatment purposes. To improve the electrical and mechanical properties of flexible electronics, nanoscale fabrications using novel nanomaterials are required. Advancements in nanoscale fabrication methods allow the construction of active materials that can be combined with ultrathin soft substrates to form flexible electronics with high performances and reliability. In this review, a wide range of flexible electronic applications via nanoscale fabrication methods, classified as either top-down or bottom-up approaches, including conventional photolithography, soft lithography, nanoimprint lithography, growth, assembly, and chemical vapor deposition (CVD, are introduced, with specific fabrication processes and results. Here, our aim is to introduce recent progress on the various fabrication methods for flexible electronics, based on novel nanomaterials, using application examples of fundamental device components for electronics and applications in healthcare systems.

  13. Finite element simulation of stress evolution in thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Bednarz, P.

    2007-07-01

    Gas turbine materials exposed to extreme high temperature require protective coatings. To design reliable components, a better understanding of the coating failure mechanisms is required. Damage in Thermal Barrier Coating Systems (TBCs) is related to oxidation of the Bond Coat, sintering of the ceramic, thermal mismatch of the material constituents, complex shape of the BC/TGO/TBC interface, redistribution of stresses via creep and plastic deformation and crack resistance. In this work, experimental data of thermo-mechanical properties of CMSX-4, MCrAlY (Bond Coat) and APS-TBC (partially stabilized zirconia), were implemented into an FE-model in order to simulate the stress development at the metal/ceramic interface. The FE model reproduced the specimen geometry used in corresponding experiments. It comprises a periodic unit cell representing a slice of the cylindrical specimen, whereas the periodic length of the unit cell equals an idealized wavelength of the rough metal/ceramic interface. Experimental loading conditions in form of thermal cycling with a dwelltime at high temperature and consideration of continuous oxidation were simulated. By a stepwise consideration of various material properties and processes, a reference model was achieved which most realistically simulated the materials behavior. The influences of systematic parameter variations on the stress development and critical sites with respect to possible crack paths were shown. Additionally, crack initiation and propagation at the peak of asperity at BC/TGO interface was calculated. It can be concluded that a realistic modeling of stress development in TBCs requires at least reliable data of i) BC and TGO plasticity, ii) BC and TBC creep, iii) continuous oxidation including in particular lateral oxidation, and iv) critical energy release rate for interfaces (BC/TGO, TGO/TBC) and for each layer. The main results from the performed parametric studies of material property variations suggest that

  14. Superphenix 1 primary handling system fabrication and testing

    International Nuclear Information System (INIS)

    Branchu, J.; Ebbinghaus, K.; Gigarel, C.

    1985-01-01

    Primary handling covers the operations performed for spent fuel removal, new fuel insertion, and the insodium storage outside the new or spent fuel vessel. This equipment typifies many of the difficulties encountered with the project as a whole: fabrication coordination when several countries are involved and design and construction of very large, relatively complex components. Detailed design studies were mainly influenced by thermal and seismic requirements, as applicable to sodium-immersed structures. Where possible, well-tried mechanical solutions were used, but widely differing techniques were involved, ranging from the high precision fabrication of structures and mechanisms comprising numerous component parts, implying complex machining operations. No particular problems were encountered during the sodium testing of the primary handling equipment. Trends for the 1500-MW (electric) breeder include investigation of the advisability of fuel storage in the core lattice and the possibility of handling system simplification

  15. Toward an Active Fabric-Based Air Decontamination System

    National Research Council Canada - National Science Library

    Gaddy, G. A; Bratcher, Matthew S; Mills, G; Huang, S; Slaten, B. L; Debortoli, J

    2004-01-01

    ...) particles that were grafted on cotton fabric and on TiO2 particles that were embedded in glass fabric Modified TiO2 particles were grafted onto cotton fabric and irradiated in the presence of CHCl3...

  16. Engineering task plan for the development, fabrication and installation of rotary mode core sample truck grapple hoist box level wind system

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    This Engineering Task Plan is to design, generate fabrication drawings, fabricate, test, and install the grapple hoist level wind system for Rotary Mode Core Sample Trucks (RMCST) 3 and 4. Deliverables will include generating fabrication drawings, fabrication of one level wind system, updating fabrication drawings as required, and installation of level wind systems on RMCST 3 or 4. The installation of the level wind systems will be done during a preventive maintenance outage

  17. Use of digital impression systems with intraoral scanners for fabricating restorations and fixed dental prostheses.

    Science.gov (United States)

    Takeuchi, Yoshimasa; Koizumi, Hiroyasu; Furuchi, Mika; Sato, Yohei; Ohkubo, Chikahiro; Matsumura, Hideo

    2018-01-01

    Accurate impressions are essential in fabri-cating dental restorations and fixed dental prostheses. During the last decade, digital impression systems have improved substantially. This review discusses the accuracy of digital impression systems for fabrication of dental restorations and fixed dental prostheses. A literature search in PubMed was performed for the period from July 2010 through June 2017. The search keywords were Cerec, digital impression, direct digitalization, indirect digitalization, and intraoral scanner. Only relevant studies are summarized and discussed in this review. In general, the latest systems have considerably reduced the time required for impression making, and the accuracy and marginal fit of digital impression systems have recently improved. Restorations and fixed dental prostheses fabricated with currently available digital impression systems and intraoral scanners exhibit clinically acceptable ranges of marginal gap in both direct and indirect procedures.

  18. Digital fabrication

    CERN Document Server

    2012-01-01

    The Winter 2012 (vol. 14 no. 3) issue of the Nexus Network Journal features seven original papers dedicated to the theme “Digital Fabrication”. Digital fabrication is changing architecture in fundamental ways in every phase, from concept to artifact. Projects growing out of research in digital fabrication are dependent on software that is entirely surface-oriented in its underlying mathematics. Decisions made during design, prototyping, fabrication and assembly rely on codes, scripts, parameters, operating systems and software, creating the need for teams with multidisciplinary expertise and different skills, from IT to architecture, design, material engineering, and mathematics, among others The papers grew out of a Lisbon symposium hosted by the ISCTE-Instituto Universitario de Lisboa entitled “Digital Fabrication – A State of the Art”. The issue is completed with four other research papers which address different mathematical instruments applied to architecture, including geometric tracing system...

  19. Design, fabrication and testing of a 5-Hz acoustic exciter system

    Science.gov (United States)

    Lundy, D. H.; Robinson, G. D.

    1973-01-01

    A 5-Hz acoustic excitation system was designed, fabricated and checked out for use in the modulation of a stagnant gas volume contained in an absorption cell. A detailed system description of the test equipment, both mechanical and electronic, and an operating procedure are included. Conclusions are also presented.

  20. Design, fabrication, and characterization of a solenoid system to ...

    Indian Academy of Sciences (India)

    system to generate magnetic field for an ECR proton source. S K JAIN .... The bore of the solenoid coils was fabricated using high voltage glass epoxy. Each ... sure drop and flow, the inlet and outlet connections were provided. ... stability of an ECR plasma source, as any small change in the distribution of the axial magnetic.

  1. Error Correction and Calibration of a Sun Protection Measurement System for Textile Fabrics

    Energy Technology Data Exchange (ETDEWEB)

    Moss, A.R.L

    2000-07-01

    Clothing is increasingly being labelled with a Sun Protection Factor number which indicates the protection against sunburn provided by the textile fabric. This Factor is obtained by measuring the transmittance of samples of the fabric in the ultraviolet region (290-400 nm). The accuracy and hence the reliability of the label depends on the accuracy of the measurement. Some sun protection measurement systems quote a transmittance accuracy at 2%T of {+-} 1.5%T. This means a fabric classified under the Australian standard (AS/NZ 4399:1996) with an Ultraviolet Protection Factor (UPF) of 40 would have an uncertainty of +15 or -10. This would not allow classification to the nearest 5, and a UVR protection category of 'excellent protection' might in fact be only 'very good protection'. An accuracy of {+-}0.1%T is required to give a UPF uncertainty of {+-}2.5. The measurement system then does not contribute significantly to the error, and the problems are now limited to sample conditioning, position and consistency. A commercial sun protection measurement system has been developed by Camspec Ltd which used traceable neutral density filters and appropriate design to ensure high accuracy. The effects of small zero offsets are corrected and the effect of the reflectivity of the sample fabric on the integrating sphere efficiency is measured and corrected. Fabric orientation relative to the light patch is considered. Signal stability is ensured by means of a reference beam. Traceable filters also allow wavelength accuracy to be conveniently checked. (author)

  2. Error Correction and Calibration of a Sun Protection Measurement System for Textile Fabrics

    International Nuclear Information System (INIS)

    Moss, A.R.L.

    2000-01-01

    Clothing is increasingly being labelled with a Sun Protection Factor number which indicates the protection against sunburn provided by the textile fabric. This Factor is obtained by measuring the transmittance of samples of the fabric in the ultraviolet region (290-400 nm). The accuracy and hence the reliability of the label depends on the accuracy of the measurement. Some sun protection measurement systems quote a transmittance accuracy at 2%T of ± 1.5%T. This means a fabric classified under the Australian standard (AS/NZ 4399:1996) with an Ultraviolet Protection Factor (UPF) of 40 would have an uncertainty of +15 or -10. This would not allow classification to the nearest 5, and a UVR protection category of 'excellent protection' might in fact be only 'very good protection'. An accuracy of ±0.1%T is required to give a UPF uncertainty of ±2.5. The measurement system then does not contribute significantly to the error, and the problems are now limited to sample conditioning, position and consistency. A commercial sun protection measurement system has been developed by Camspec Ltd which used traceable neutral density filters and appropriate design to ensure high accuracy. The effects of small zero offsets are corrected and the effect of the reflectivity of the sample fabric on the integrating sphere efficiency is measured and corrected. Fabric orientation relative to the light patch is considered. Signal stability is ensured by means of a reference beam. Traceable filters also allow wavelength accuracy to be conveniently checked. (author)

  3. Sputter deposition system for controlled fabrication of multilayers

    International Nuclear Information System (INIS)

    Di Nardo, R.P.; Takacs, P.Z.; Majkrzak, C.F.; Stefan, P.M.

    1985-06-01

    A detailed description of a sputter deposition system constructed specifically for the fabrication of x-ray and neutron multilayer monochromators and supermirrors is given. One of the principal design criteria is to maintain precise control of film thickness and uniformity over large substrate areas. Regulation of critical system parameters is fully automated so that response to feedback control information is rapid and complicated layer thickness sequences can be deposited accurately and efficiently. The use of either dc or rf magnetron sources makes it possible to satisfy the diverse material requirements of both x-ray and neutron optics

  4. Identified problems in fabricating Mobile Radioscopy System (MRS)

    International Nuclear Information System (INIS)

    Arshad Yassin; Khairul Anuar Mohd Salleh; Ab Razak Hamzah; Khari Che Ros; Hasni Hashim

    2009-01-01

    This paper describes problems found and solving method in our effort to fabricate the first up to standard mobile radioscopy system (MRS). The MRS is expected to solve problems faced by small and medium local industries to have their own digital industrial radiography system (DIR) i.e. expensive cost, lack of experience in handling radiation electronic detector, etc. Most of the problems occurred give the challenge to obtain the best radiographic image quality in terms of quantitative evaluation. With the upcoming developments, the MRS is expected to acceptable to be us in oil and gas industry and power generation plant. (Author)

  5. Design and Fabrication of Radiation Shielded Micro X-Ray Diffraction System

    International Nuclear Information System (INIS)

    Park, Yang Soon; Han, Sun Ho; Ha, Kyeong Yeong; Jee, Kwang Yong

    2006-12-01

    It has been observed that microstructure changes occur at the radial edge of pellet(rim) of the fuel at a high burn-up and extended fuel cycle. The thickness of a rim is some hundreds of micrometers. Despite its narrow range, a rim would affect the behaviour of nuclear fuel. To determine lattice parameter with micro-XRD at intervals as small as 30 - 50 μm in radial direction of irradiated fuel samples, a radiation shielded micro-XRD system was designed and fabricated. This report describes the concept, shielding analysis, the structural design and the fabrication of a radiation shielded glove box for micro-XRD system. This radiation shielded micro-XRD system will be used for analysis of lattice parameter change and the phase distribution at intervals as small as 30 - 50 μm in radial direction of the rim of an irradiated fuel sample and a fuel cladding

  6. Design and Fabrication of Radiation Shielded Micro X-Ray Diffraction System

    Energy Technology Data Exchange (ETDEWEB)

    Park, Yang Soon; Han, Sun Ho; Ha, Kyeong Yeong; Jee, Kwang Yong

    2006-12-15

    It has been observed that microstructure changes occur at the radial edge of pellet(rim) of the fuel at a high burn-up and extended fuel cycle. The thickness of a rim is some hundreds of micrometers. Despite its narrow range, a rim would affect the behaviour of nuclear fuel. To determine lattice parameter with micro-XRD at intervals as small as 30 - 50 {mu}m in radial direction of irradiated fuel samples, a radiation shielded micro-XRD system was designed and fabricated. This report describes the concept, shielding analysis, the structural design and the fabrication of a radiation shielded glove box for micro-XRD system. This radiation shielded micro-XRD system will be used for analysis of lattice parameter change and the phase distribution at intervals as small as 30 - 50 {mu}m in radial direction of the rim of an irradiated fuel sample and a fuel cladding.

  7. TGO growth and crack propagation in a thermal barrier coating

    Energy Technology Data Exchange (ETDEWEB)

    Chen, W.R.; Archer, R.; Huang, X. [National Research Council of Canada, Ottawa, ON (Canada); Marple, B.R. [National Research Council of Canada, Boucherville, PQ (Canada)

    2008-07-01

    In thermal barrier coating (TBC) systems, a continuous alumina layer developed at the ceramic topcoat/bond coat interface helps to protect the metallic bond coat from further oxidation and improve the durability of the TBC system under service conditions. However, other oxides such as spinel and nickel oxide, formed in the oxidizing environment, are believed to be detrimental to TBC durability during service at high temperatures. It was shown that in an air-plasma-sprayed (APS) TBC system, post-spraying heat treatments in low-pressure oxygen environments could suppress the formation of the detrimental oxides by promoting the formation of an alumina layer at the ceramic topcoat/bond coat interface, leading to an improved TBC durability. This work presents the influence of post-spraying heat treatments in low-pressure oxygen environments on the oxidation behaviour and durability of a thermally sprayed TBC system with high-velocity oxy-fuel (HVOF)-produced Co-32Ni-21Cr-8Al-0.5Y (wt.%) bond coat. Oxidation behaviour of the TBCs is evaluated by examining their microstructural evolution, growth kinetics of the thermally grown oxide (TGO) layers, as well as crack propagation during low frequency thermal cycling at 1050 C. The relationship between the TGO growth and crack propagation will also be discussed. (orig.)

  8. On the compatibility of single crystal superalloys with a thermal barrier coating system

    Energy Technology Data Exchange (ETDEWEB)

    Wu, R.T. [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2BP (United Kingdom); Reed, R.C. [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2BP (United Kingdom)], E-mail: r.reed@birmingham.ac.uk

    2008-02-15

    The compatibility of three Co-containing prototype single crystal nickel-based superalloys with a thermal barrier coating (TBC) system is examined. These contain 2.1, 8.4 and 12.6 at.% Co; the concentrations of Al, Cr, Ta, W, Re, Hf are identical and chosen to be representative of advanced grades of these alloys. The TBC consists of an yttria-stabilized zirconia (YSZ) layer formed by electron beam physical vapour deposition (EB-PVD) and a bond coat made by electrodeposited platinum with a subsequent interdiffusion heat treatment - a so-called 'platinum-diffused' bond coat. The resistance to spallation of the TBC system is degraded as the Co content of the substrate increases. Wavelength-dispersive X-ray analysis and secondary ion mass spectrometry indicate that quantities of Co are present in the thermally grown oxide (TGO) by the time that failure occurs, this effect being most pronounced when the Co content of the substrate is high; the TGO is then more wavy and convoluted. The bond coat consists exclusively of the {gamma} and {gamma}' phases, with the balance shifting towards {gamma} with increasing thermal exposure; the loss of Al from the bond coat due to TGO formation means that the TGO is eventually in contact with the {gamma} phase solely, which is enriched in Co.

  9. Fe nanodot system fabricated by non-lithographic method and its structural properties

    International Nuclear Information System (INIS)

    Chu Van Chiem; Nguyen Thi Thu Ha; Ngo Thi Thanh Tam; Nguyen Van Chuc; Phan Ngoc Minh; Li Huying; Seo Jae Muyng

    2009-01-01

    In this work, we study the magnetic structure and morphology of the Fe nanodot system fabricated by the non-lithographic method, using anodic aluminum oxide (AAO) membrane as a template. By the two-steps aluminum anodization, the AAO patterns with the hexagonal pore arrangement have been achieved. Using AAO pattern as a template, under suitable conditions we successfully deposited the iron metal in the pores by the thermal vacuum evaporation. By the exposure of the deposited system from the bottom of the AAO membrane, the hexagonal ordered Fe nanodot system has been obtained. The morphologies of the nanodot system were imaged by the Atomic Force Microscopy (AFM) and Field Emission Scanning Microscopy (FESEM) methods. The magnetic structures were investigated by the Energy Dispersive X-Ray Fluorescence Spectroscopy (EDS) and Magnetic Force Microscopy (MFM) methods. Experimental results confirmed that the MFM image of the fabricated Fe nanodot system is similar to their AFM image.

  10. Fe nanodot system fabricated by non-lithographic method and its structural properties

    Energy Technology Data Exchange (ETDEWEB)

    Chiem, Chu Van; Thu Ha, Nguyen Thi; Thanh Tam, Ngo Thi; Chuc, Nguyen Van; Minh, Phan Ngoc [Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Road, Cau Giay Distr., Hanoi (Viet Nam); Huying, Li; Seo Jae Muyng [Physics department, Chonbuk National University (Korea, Republic of)], E-mail: chucnv@ims.vast.ac.vn

    2009-09-01

    In this work, we study the magnetic structure and morphology of the Fe nanodot system fabricated by the non-lithographic method, using anodic aluminum oxide (AAO) membrane as a template. By the two-steps aluminum anodization, the AAO patterns with the hexagonal pore arrangement have been achieved. Using AAO pattern as a template, under suitable conditions we successfully deposited the iron metal in the pores by the thermal vacuum evaporation. By the exposure of the deposited system from the bottom of the AAO membrane, the hexagonal ordered Fe nanodot system has been obtained. The morphologies of the nanodot system were imaged by the Atomic Force Microscopy (AFM) and Field Emission Scanning Microscopy (FESEM) methods. The magnetic structures were investigated by the Energy Dispersive X-Ray Fluorescence Spectroscopy (EDS) and Magnetic Force Microscopy (MFM) methods. Experimental results confirmed that the MFM image of the fabricated Fe nanodot system is similar to their AFM image.

  11. Fabrication of polystyrene microfluidic devices using a pulsed CO2 laser system

    KAUST Repository

    Li, Huawei

    2013-10-10

    In this article, we described a simple and rapid method for fabrication of droplet microfluidic devices on polystyrene substrate using a CO2 laser system. The effects of the laser power and the cutting speed on the depth, width and aspect ratio of the microchannels fabricated on polystyrene were investigated. The polystyrene microfluidic channels were encapsulated using a hot press bonding technique. The experimental results showed that both discrete droplets and laminar flows could be obtained in the device.

  12. Fabrication of polystyrene microfluidic devices using a pulsed CO2 laser system

    KAUST Repository

    Li, Huawei; Fan, Yiqiang; Foulds, Ian G.; Kodzius, Rimantas

    2013-01-01

    In this article, we described a simple and rapid method for fabrication of droplet microfluidic devices on polystyrene substrate using a CO2 laser system. The effects of the laser power and the cutting speed on the depth, width and aspect ratio of the microchannels fabricated on polystyrene were investigated. The polystyrene microfluidic channels were encapsulated using a hot press bonding technique. The experimental results showed that both discrete droplets and laminar flows could be obtained in the device.

  13. Intermetallic Al-, Fe-, Co- and Ni-Based Thermal Barrier Coatings Prepared by Cold Spray for Applications on Low Heat Rejection Diesel Engines

    Science.gov (United States)

    Leshchinsky, E.; Sobiesiak, A.; Maev, R.

    2018-02-01

    Conventional thermal barrier coating (TBC) systems consist of a duplex structure with a metallic bond coat and a ceramic heat insulating topcoat. They possess the desired low thermal conductivity, but at the same time they are very brittle and sensitive to thermal shock and thermal cycling due to the inherently low coefficient of thermal expansion. Recent research activities are focused on the developing of multilayer TBC structures obtained using cold spraying and following annealing. Aluminum intermetallics have demonstrated thermal and mechanical properties that allow them to be used as the alternative TBC materials, while the intermetallic layers can be additionally optimized to achieve superior thermal physical properties. One example is the six layer TBC structure in which cold sprayed Al-based intermetallics are synthesized by annealing in nitrogen atmosphere. These multilayer coating systems demonstrated an improved thermal fatigue capability as compared to conventional ceramic TBC. The microstructures and properties of the coatings were characterized by SEM, EDS and mechanical tests to define the TBC material properties and intermetallic formation mechanisms.

  14. Performance of Plain Woven Jute Fabric-Reinforced Polyester Matrix Composite in Multilayered Ballistic System

    Directory of Open Access Journals (Sweden)

    Sergio Neves Monteiro

    2018-02-01

    Full Text Available The ballistic performance of plain woven jute fabric-reinforced polyester matrix composites was investigated as the second layer in a multilayered armor system (MAS. Volume fractions of jute fabric, up to 30 vol %, were mixed with orthophthalic polyester to fabricate laminate composites. Ballistic tests were conducted using high velocity 7.62 mm ammunition. The depth of penetration caused by the bullet in a block of clay witness, simulating a human body, was used to evaluate the MAS ballistic performance according to the international standard. The fractured materials after tests were analyzed by scanning electron microscopy (SEM. The results indicated that jute fabric composites present a performance similar to that of the much stronger Kevlar™, which is an aramid fabric laminate, as MAS second layer with the same thickness. The mechanism of this similar ballistic behavior as well as the comparative advantages of the jute fabric composites over the Kevlar™ are discussed.

  15. Design and fabrication of a micro parallel mechanism system using MEMS technologies

    Science.gov (United States)

    Chin, Chi-Te

    A parallel mechanism is seen as an attractive method of fabricating a multi-degree of freedom micro-stage on a chip. The research team at Arizona State University has experience with several potential parallel mechanisms that would be scaled down to micron dimensions and fabricated by using the silicon process. The researcher developed a micro parallel mechanism that allows for planar motion having two translational motions and one rotational motion (e.g., x, y, theta). The mask design shown in Appendix B is an example of a planar parallel mechanism, however, this design would only have a few discrete positions given the nature of the fully extended or fully retracted electrostatic motor. The researcher proposes using a rotary motor (comb-drive actuator with gear chain system) coupled to a rack and pinion for finer increments of linear motion. The rotary motor can behave as a stepper motor by counting drive pulses, which is the basis for a simple open loop control system. This system was manufactured at the Central Regional MEMS Research Center (CMEMS), National Tsing-Hua University, and supported by the National Science Council, Taiwan. After the microstructures had been generated, the proceeding devices were released and an experiment study was performed to demonstrate the feasibility of the proposed micro-stage devices. In this dissertation, the micro electromechanical system (MEMS) fabrication technologies were introduced. The development of this parallel mechanism system will initially focus on development of a planar micro-stage. The design of the micro-stage will build on the parallel mechanism technology, which has been developed for manufacturing, assembly, and flight simulator applications. Parallel mechanism will give the maximum operating envelope with a minimum number of silicon levels. The ideally proposed mechanism should comprise of a user interface, a micro-stage and a non-silicon tool, which is difficult to accomplish by current MEMS technology

  16. Combined laser and atomic force microscope lithography on aluminum: Mask fabrication for nanoelectromechanical systems

    DEFF Research Database (Denmark)

    Berini, Abadal Gabriel; Boisen, Anja; Davis, Zachary James

    1999-01-01

    A direct-write laser system and an atomic force microscope (AFM) are combined to modify thin layers of aluminum on an oxidized silicon substrate, in order to fabricate conducting and robust etch masks with submicron features. These masks are very well suited for the production of nanoelectromecha......A direct-write laser system and an atomic force microscope (AFM) are combined to modify thin layers of aluminum on an oxidized silicon substrate, in order to fabricate conducting and robust etch masks with submicron features. These masks are very well suited for the production...... writing, and to perform submicron modifications by AFM oxidation. The mask fabrication for a nanoscale suspended resonator bridge is used to illustrate the advantages of this combined technique for NEMS. (C) 1999 American Institute of Physics. [S0003-6951(99)00221-1]....

  17. Trial fabrication and preliminary characterization of electrical insulator for liquid metal system

    International Nuclear Information System (INIS)

    Nakamichi, Masaru; Kawamura, Hiroshi; Oyamada, Rokuro

    1995-03-01

    In the design of the liquid metal blanket, MHD pressure drop is one of critical issues. Ceramic coating on the surface of structural material is considered as an electrical insulator to reduce the MHD pressure drop. Ceramic coating such as Y 2 O 3 is a promising electrical insulator due to its high electrical resistivity and good compatibility with liquid lithium. This report describes the trial fabrication and preliminary characterization of electrical insulator for a design study of the liquid metal system. From the results of trial fabrication and preliminary characterization, it is concluded that densified atmospheric plasma spray Y 2 O 3 coating with 410SS undercoating between 316SS substrate and Y 2 O 3 coating is suitable for Y 2 O 3 coating fabrication. (author)

  18. Efficient outdoor performance of esthetic bifacial a-Si:H semi-transparent PV modules

    International Nuclear Information System (INIS)

    Myong, Seung Yeop; Jeon, Sang Won

    2016-01-01

    Highlights: • 1.43 m"2 a-Si:H semi-transparent PV modules with emotionally inoffensive and esthetically pleasing colors are developed. • Seasonal outdoor performance of the developed colorful PV modules is measured and simulated. • The bifacial TBC a-Si:H semi-transparent PV module performs at a superior annual electrical energy output. • An impressive performance ratio of 124.5% is achieved by surpassing a simulated prediction considerably. - Abstract: We developed bifacial transparent back contact (TBC) hydrogenated amorphous silicon (a-Si:H) semi-transparent glass-to-glass photovoltaic (PV) modules with emotionally inoffensive and esthetically pleasing colors have been developed by combining the transparent back contact and color of the back glass. Due to the high series resistance of the transparent back contact, the bifacial TBC a-Si:H semi-transparent PV modules had a lower rated power after light soaking than the monofacial opaque (metal) back contact (OBC) a-Si:H semi-transparent PV modules fabricated using the additional laser scribing patterns. However, the TBC a-Si:H semi-transparent PV module produced a higher annual electrical energy output than the OBC a-Si:H semi-transparent PV module thanks to bifacial power generation during the outdoor field test. In particular, the performance ratio of the TBC a-Si:H semi-transparent PV module measured at the optimal tilt angle of 30° surpassed its simulated prediction by a drastically high value of 124.5%. At a higher tilt angle of 85°, bifacial power generation produced a higher deviation between the measured and simulated annual performance of the TBC a-Si:H semi-transparent PV module. Since the reflected albedo has a tendency to increase toward higher tilt angles, bifacial power generation can compensate for the loss of lower direct plane-of-array irradiation at a higher tilt angle. Therefore, the TBC a-Si:H semi-transparent PV module is suitable for the vertically mounted building integrated

  19. High energy ballistic and fracture comparison between multilayered armor systems using non-woven curaua fabric composites and aramid laminates

    Directory of Open Access Journals (Sweden)

    Fábio de Oliveira Braga

    2017-10-01

    Full Text Available For personal protection against high kinetic energy projectiles, multilayered armor systems (MAS are usually the best option. They combine synergistically the properties of different materials such as ceramics, composites and metals. In the present work, ballistic tests were performed to evaluate multilayered armor systems (MAS using curaua non-woven fabric epoxy composites as second layer. A comparison to a MAS using aramid (Kevlar™ fabric laminates was made. The results showed that the curaua non-woven fabric composites are suitable to the high ballistic applications, and are promising substitutes for aramid fabric laminates. Keywords: Composite, Natural fiber, Curaua fiber, Non-woven fabric, Aramid laminate, Ballistic test

  20. Development of Reliability Based Life Prediction Methods for Thermal and Environmental Barrier Coatings in Ceramic Matrix Composites

    Science.gov (United States)

    Shah, Ashwin

    2001-01-01

    Literature survey related to the EBC/TBC (environmental barrier coating/thermal barrier coating) fife models, failure mechanisms in EBC/TBC and the initial work plan for the proposed EBC/TBC life prediction methods development was developed as well as the finite element model for the thermal/stress analysis of the GRC-developed EBC system was prepared. Technical report for these activities is given in the subsequent sections.

  1. Monitoring thermally grown oxides under thermal barrier coatings using photoluminescence piezospectroscopy (PLPS)

    Energy Technology Data Exchange (ETDEWEB)

    Del Corno, A.; De Maria, L.; Rinaldi, C. [ERSE, Milan (Italy); Nalin, L.; Simms, N.J. [Cranfield Univ., Bedford (United Kingdom). Energy Technology Centre

    2010-07-01

    The use of thermal barrier coatings (TBCs) on cooled components in industrial gas turbine has enabled higher inlet gas temperatures to be used and hence higher efficiencies to be achieved, without increasing component metal temperatures. However TBCs have a complex coating structure that during high temperature exposure and thermal cycling modifies until TBC spalling which can result in dangerous over-heating of components. This paper reports the results of a TBC exposure programme planned to monitor TGOs development in an example TBC system in terms of both stress evolution within the TGOs and TGO growth. The COST538 reference TBC system was used: an yttria stabilised zirconia TBC applied to an Amdry 995 bond coat on an CMSX-4 substrate. Samples were in the form of 10 mm diameter bars, with the TBC applied to their curved surface. Coated samples were exposed in simulated combustion gases at temperatures 850, 900 and 950 C for periods of up to 10,000 hours. Every 1000 hours samples were cooled and weighed to monitor the progression of the oxidation: selected samples NDT inspected using PLPS and/or destructive examination. Cross-sections were prepared and examined in a scanning electron microscope (SEM) at multiple locations to determine TGO thickness distributions. PLPS spectra were measured and elaborated with a system self developed in ERSE, able to calculate and map the TGO residual stress values under columnar TBCs. So the positions could be evidenced where the damage of the TBC /TGO/BC interface is higher on the exposed bars. The data of TGO thickness distributions and PLPS stress measurement distributions were compared to the exposures carried out on samples to identify and quantify trends in their development. Metallography confirmed that the PLPs technique can reliably detect interface cracking before visible EB-PVD TBC spalling. (orig.)

  2. Secure Automated Fabrication: an overview of remote breeder fuel fabrication

    International Nuclear Information System (INIS)

    Nyman, D.H.; Graham, R.A.

    1983-10-01

    The Secure Automated Fabrication (SAF) line is an automated, remotely controlled breeder fuel pin fabrication process which is to be installed in the Fuels and Materials Examination Facility (FMEF). The FMEF is presently under construction at Hanford and is scheduled for completion in 1984. The SAF line is scheduled for startup in 1987 and will produce mixed uranium-plutonium fuel pins for the Fast Flux Test Facility (FFTF) and the Clinch River Breeder Reactor Plant (CRBRP). The fabrication line and support systems are described

  3. Material and fabrication considerations for the CANDU-PHWR heat transport system

    International Nuclear Information System (INIS)

    Filipovic, A.; Price, E.G.; Barber, D.; Nickerson, J.

    1987-03-01

    CANDU PHWR nuclear systems have used carbon steel material for over 25 years. The accumulated operating experience of over 200 reactor years has proven this unique AECL approach to be both technically and economically attractive. This paper discusses design, material and fabrication considerations for out-reactor heat transport system major components. The contribution of this unique choice of materials and equipment to the outstanding CANDU performance is briefly covered

  4. New Fabrication Method of Three-Electrode System on Cylindrical Capillary Surface as a Flexible Implantable Microneedle

    Science.gov (United States)

    Yang, Zhuoqing; Zhang, Yi; Itoh, Toshihiro; Maeda, Ryutaro

    2013-04-01

    In this present paper, a three-electrode system has been fabricated and integrated on the cylindrical polymer capillary surface by micromachining technology, which could be used as a flexible and implantable microneedle for glucose sensor application in future. A UV lithography system is successfully developed for high resolution alignment on cylindrical substrates. The multilayer alignment exposure for cylindrical polymer capillary substrate is for the first time realized utilizing the lithography system. The ±1 μm alignment precision has been realized on the 330 μm-outer diameter polymer capillary surface, on which the three-electrode structure consisting of two platinum electrodes and one Ag/AgCl reference electrode has been fabricated. The fabricated whole device as microneedle for glucose sensor application has been also characterized in 1 mol/L KCl and 0.02 mol/L K3Fe(CN)6 mix solution. The measured cyclic voltammetry curve shows that the prepared three-electrode system has a good redox property.

  5. Fabrication of ATALANTE Dissolver Off-Gas Sorbent-Based Capture System

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Jr., Joseph Franklin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jubin, Robert Thomas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-04-30

    A small sorbent-based capture system was designed that could be placed in the off-gas line from the fuel dissolver in the ATALANTE hot cells with minimal modifications to the ATALANTE dissolver off-gas system. Discussions with personnel from the ATALANTE facility provided guidance that was used for the design. All components for this system have been specified, procured, and received on site at Oak Ridge National Laboratory (ORNL), meeting the April 30, 2015, milestone for completing the fabrication of the ATALANTE dissolver off-gas capture system. This system will be tested at ORNL to verify operation and to ensure that all design requirements for ATALANTE are met. Modifications to the system will be made, as indicated by the testing, before the system is shipped to ATALANTE for installation in the hot cell facility.

  6. Extrathoracic manifestations of tuberculosis; Extrathorakale Manifestationen der Tuberkulose

    Energy Technology Data Exchange (ETDEWEB)

    Kienzl-Palma, D.; Prosch, H. [Medizinische Universitaet Wien, Abteilung fuer Allgemeine Radiologie und Kinderradiologie, Universitaetsklinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

    2016-10-15

    Besides the lungs, tuberculosis (TB) can affect any organ system. In most cases, extrathoracic TB occurs in immunosuppressed patients as part of a severe illness via hematogenous spread. Extrathoracic involvement most commonly involves abdominal organs, especially the urogenital tract and less commonly the central nervous system (CNS) and the musculoskeletal system. Most frequently, computed tomography (CT) is used for detecting extrathoracic TB manifestations, except for CNS and musculoskeletal manifestations, where contrast-enhanced magnetic resonance imaging (MRI) is the gold standard. Extrathoracic manifestations of TB may be indistinguishable from inflammatory or malignant causes. Due to unspecific symptoms the diagnosis is often delayed. This article summarizes and discusses the various radiological manifestations of extrathoracic manifestation of TB. Radiological modalities for screening extrathoracic TB are CT and MRI. Conventional X-radiographs do not play a role in the diagnosis of extrathoracic TB. The possibility of extrathoracic TB should be considered particularly in immunosuppressed patients, such as the homeless, alcoholics or drug addicts or in patients with an immigrant background from the endemic areas of TB. The most likely site of extrathoracic TB is the abdomen; however, infections of the CNS or musculoskeletal systems and multisystem infections can also occur. In patients with suspected extrathoracic TB, radiological modalities for screening are CT, especially for abdominal infections and lymphadenopathy and MRI with contrast media for the musculoskeletal system and the CNS. (orig.) [German] Die Tuberkulose (Tbc) kann neben der Lunge prinzipiell jedes Organsystem befallen. In den meisten Faellen tritt eine extrathorakale Tbc bei Immunsupprimierten im Rahmen eines schweren Krankheitsverlaufs durch haematogene Aussaat auf. Der haeufigste extrathorakale Befall betrifft das Abdomen und hier v. a. den Urogenitaltrakt. Daneben kann es zum Befall

  7. Computational design and experimental validation of new thermal barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin [Louisiana State Univ., Baton Rouge, LA (United States)

    2015-03-31

    The focus of this project is on the development of a reliable and efficient ab initio based computational high temperature material design method which can be used to assist the Thermal Barrier Coating (TBC) bond-coat and top-coat design. Experimental evaluations on the new TBCs are conducted to confirm the new TBCs’ properties. Southern University is the subcontractor on this project with a focus on the computational simulation method development. We have performed ab initio density functional theory (DFT) method and molecular dynamics simulation on screening the top coats and bond coats for gas turbine thermal barrier coating design and validation applications. For experimental validations, our focus is on the hot corrosion performance of different TBC systems. For example, for one of the top coatings studied, we examined the thermal stability of TaZr2.75O8 and confirmed it’s hot corrosion performance.

  8. Self-healing thermal barrier coatings; with application to gas turbine engines

    NARCIS (Netherlands)

    Ponnusami, S.A.

    2013-01-01

    Thermal Barrier Coating (TBC) systems have been applied in turbine engines for aerospace and power plants since the beginning of the 1980s to increase the energy efficiency of the engine, by allowing for higher operation temperatures. TBC systems on average need to be replaced about four times

  9. A Fully Integrated Humidity Sensor System-on-Chip Fabricated by Micro-Stamping Technology

    Science.gov (United States)

    Huang, Che-Wei; Huang, Yu-Jie; Lu, Shey-Shi; Lin, Chih-Ting

    2012-01-01

    A fully integrated humidity sensor chip was designed, implemented, and tested. Utilizing the micro-stamping technology, the pseudo-3D sensor system-on-chip (SSoC) architecture can be implemented by stacking sensing materials directly on the top of a CMOS-fabricated chip. The fabricated sensor system-on-chip (2.28 mm × 2.48 mm) integrated a humidity sensor, an interface circuit, a digital controller, and an On-Off Keying (OOK) wireless transceiver. With low power consumption, i.e., 750 μW without RF operation, the sensitivity of developed sensor chip was experimentally verified in the relative humidity (RH) range from 32% to 60%. The response time of the chip was also experimentally verified to be within 5 seconds from RH 36% to RH 64%. As a consequence, the implemented humidity SSoC paves the way toward the an ultra-small sensor system for various applications.

  10. Digital fabrication of multi-material biomedical objects

    Energy Technology Data Exchange (ETDEWEB)

    Cheung, H H; Choi, S H, E-mail: shchoi@hku.h [Department of Industrial and Manufacturing Systems Engineering, University of Hong Kong, Pokfulam Road (Hong Kong)

    2009-12-15

    This paper describes a multi-material virtual prototyping (MMVP) system for modelling and digital fabrication of discrete and functionally graded multi-material objects for biomedical applications. The MMVP system consists of a DMMVP module, an FGMVP module and a virtual reality (VR) simulation module. The DMMVP module is used to model discrete multi-material (DMM) objects, while the FGMVP module is for functionally graded multi-material (FGM) objects. The VR simulation module integrates these two modules to perform digital fabrication of multi-material objects, which can be subsequently visualized and analysed in a virtual environment to optimize MMLM processes for fabrication of product prototypes. Using the MMVP system, two biomedical objects, including a DMM human spine and an FGM intervertebral disc spacer are modelled and digitally fabricated for visualization and analysis in a VR environment. These studies show that the MMVP system is a practical tool for modelling, visualization, and subsequent fabrication of biomedical objects of discrete and functionally graded multi-materials for biomedical applications. The system may be adapted to control MMLM machines with appropriate hardware for physical fabrication of biomedical objects.

  11. Digital fabrication of multi-material biomedical objects

    International Nuclear Information System (INIS)

    Cheung, H H; Choi, S H

    2009-01-01

    This paper describes a multi-material virtual prototyping (MMVP) system for modelling and digital fabrication of discrete and functionally graded multi-material objects for biomedical applications. The MMVP system consists of a DMMVP module, an FGMVP module and a virtual reality (VR) simulation module. The DMMVP module is used to model discrete multi-material (DMM) objects, while the FGMVP module is for functionally graded multi-material (FGM) objects. The VR simulation module integrates these two modules to perform digital fabrication of multi-material objects, which can be subsequently visualized and analysed in a virtual environment to optimize MMLM processes for fabrication of product prototypes. Using the MMVP system, two biomedical objects, including a DMM human spine and an FGM intervertebral disc spacer are modelled and digitally fabricated for visualization and analysis in a VR environment. These studies show that the MMVP system is a practical tool for modelling, visualization, and subsequent fabrication of biomedical objects of discrete and functionally graded multi-materials for biomedical applications. The system may be adapted to control MMLM machines with appropriate hardware for physical fabrication of biomedical objects.

  12. Heat Release Property and Fire Performance of the Nomex/Cotton Blend Fabric Treated with a Nonformaldehyde Organophosphorus System

    Directory of Open Access Journals (Sweden)

    Charles Q. Yang

    2016-09-01

    Full Text Available Blending Nomex® with cotton improves its affordability and serviceability. Because cotton is a highly flammable fiber, Nomex®/cotton blend fabrics containing more than 20% cotton require flame-retardant treatment. In this research, combination of a hydroxyl functional organophosphorus oligmer (HFPO and 1,2,3,4-butanetetracarboxylic acid (BTCA was used for flame retardant finishing of the 65/35 Nomex®/cotton blend woven fabric. The system contains HFPO as a flame retardant, BTCA as a bonding agent, and triethenolamine (TEA as a reactive additive used to enhance the performance of HFPO/BTCA. Addition of TEA improves the hydrolysis resistance of the HFPO/BTCA crosslinked polymeric network on the blend fabric. Additionally, TEA enhances HFPO’s flame retardant performance by reducing formation of calcium salts and also by providing synergistic nitrogen to the treated blend fabric. The Nomex®/cotton blend fabric treated with the HFPO/BTCA/TEA system shows high flame resistance and high laundering durability at a relatively low HFPO concentration of 8% (w/w. The heat release properties of the treated Nomex®/cotton blend fabric were measured using microscale combustion calorimetry. The functions of BTCA; HFPO and TEA on the Nomex®/cotton blend fabric were elucidated based on the heat release properties, char formation, and fire performance of the treated blend fabric.

  13. Fabricating 3D figurines with personalized faces.

    Science.gov (United States)

    Tena, J Rafael; Mahler, Moshe; Beeler, Thabo; Grosse, Max; Hengchin Yeh; Matthews, Iain

    2013-01-01

    We present a semi-automated system for fabricating figurines with faces that are personalised to the individual likeness of the customer. The efficacy of the system has been demonstrated by commercial deployments at Walt Disney World Resort and Star Wars Celebration VI in Orlando Florida. Although the system is semi automated, human intervention is limited to a few simple tasks to maintain the high throughput and consistent quality required for commercial application. In contrast to existing systems that fabricate custom heads that are assembled to pre-fabricated plastic bodies, our system seamlessly integrates 3D facial data with a predefined figurine body into a unique and continuous object that is fabricated as a single piece. The combination of state-of-the-art 3D capture, modelling, and printing that are the core of our system provide the flexibility to fabricate figurines whose complexity is only limited by the creativity of the designer.

  14. Design and fabrication of micro X-ray diffraction system

    International Nuclear Information System (INIS)

    Park, Yang Soon; Han, Sun Ho; Kim, Jong Goo; Jee, Kwang Yong

    2006-10-01

    It has been observed that microstructure changes occur at the pellet periphery(rim) of the fuel at very high burn-up. Despite its narrow range (below some hundreds microns in depth), this peripheral region(rim) determines the behaviour of nuclear fuel. To determine lattice parameter with XRD at intervals as small as 30-50 μ m in radial direction of irradiated fuel samples, a micro X-ray diffraction system was designed and fabricated. This report describes the micro X-ray diffraction system consisted of an X-ray microbeam alignment system and a sample micro translation system, its characterization, and its performance test through the analysis for the micro region of some specimens. This system will be set in a radiation shielded glove box, and then used for analysis of lattice parameter change and the phase change at intervals as small as 30-50 μ m in radial direction of the rim of an irradiated fuel sample and a fuel cladding

  15. Design and fabrication of micro X-ray diffraction system

    Energy Technology Data Exchange (ETDEWEB)

    Park, Yang Soon; Han, Sun Ho; Kim, Jong Goo; Jee, Kwang Yong

    2006-10-15

    It has been observed that microstructure changes occur at the pellet periphery(rim) of the fuel at very high burn-up. Despite its narrow range (below some hundreds microns in depth), this peripheral region(rim) determines the behaviour of nuclear fuel. To determine lattice parameter with XRD at intervals as small as 30-50 {mu} m in radial direction of irradiated fuel samples, a micro X-ray diffraction system was designed and fabricated. This report describes the micro X-ray diffraction system consisted of an X-ray microbeam alignment system and a sample micro translation system, its characterization, and its performance test through the analysis for the micro region of some specimens. This system will be set in a radiation shielded glove box, and then used for analysis of lattice parameter change and the phase change at intervals as small as 30-50 {mu} m in radial direction of the rim of an irradiated fuel sample and a fuel cladding.

  16. Fabrication and Analysis of Tapered Tip Silicon Microneedles for MEMS based Drug Delivery System

    Directory of Open Access Journals (Sweden)

    Muhammad Waseem Ashraf

    2010-11-01

    Full Text Available In this paper, a novel design of transdermal drug delivery (TDD system is presented. The proposed system consists of controlled electronic circuit and microelectromechanical system (MEMS based devices like microneedles, micropump, flow sensor, and blood pressure sensor. The aim of this project is to develop a system that can eliminate the limitations associated with oral therapy. In this phase tapered tip silicon microneedles have been fabricated using inductively coupled plasma (ICP etching technology. Using ANSYS, simulation of microneedles has been conducted before the fabrication process to test the design suitability for TDD. More over multifield analysis of reservoir integrated with microneedle array using piezoelectric actuator has also been performed. The effects of frequency and voltage on actuator and fluid flow rate through 6×6 microneedle array have been investigated. This work provides envisage data to design suitable devices for TDD.

  17. Fabrication and electronic transport studies of single nanocrystal systems

    Energy Technology Data Exchange (ETDEWEB)

    Klein, David Louis [Univ. of California, Berkeley, CA (United States). Dept. of Physics

    1997-05-01

    Semiconductor and metallic nanocrystals exhibit interesting electronic transport behavior as a result of electrostatic and quantum mechanical confinement effects. These effects can be studied to learn about the nature of electronic states in these systems. This thesis describes several techniques for the electronic study of nanocrystals. The primary focus is the development of novel methods to attach leads to prefabricated nanocrystals. This is because, while nanocrystals can be readily synthesized from a variety of materials with excellent size control, means to make electrical contact to these nanocrystals are limited. The first approach that will be described uses scanning probe microscopy to first image and then electrically probe surfaces. It is found that electronic investigations of nanocrystals by this technique are complicated by tip-sample interactions and environmental factors such as salvation and capillary forces. Next, an atomic force microscope technique for the catalytic patterning of the surface of a self assembled monolayer is described. In principle, this nano-fabrication technique can be used to create electronic devices which are based upon complex arrangements of nanocrystals. Finally, the fabrication and electrical characterization of a nanocrystal-based single electron transistor is presented. This device is fabricated using a hybrid scheme which combines electron beam lithography and wet chemistry to bind single nanocrystals in tunneling contact between closely spaced metallic leads. In these devices, both Au and CdSe nanocrystals show Coulomb blockade effects with characteristic energies of several tens of meV. Additional structure is seen the transport behavior of CdSe nanocrystals as a result of its electronic structure.

  18. A Fully Integrated Humidity Sensor System-on-Chip Fabricated by Micro-Stamping Technology

    Directory of Open Access Journals (Sweden)

    Chih-Ting Lin

    2012-08-01

    Full Text Available A fully integrated humidity sensor chip was designed, implemented, and tested. Utilizing the micro-stamping technology, the pseudo-3D sensor system-on-chip (SSoC architecture can be implemented by stacking sensing materials directly on the top of a CMOS-fabricated chip. The fabricated sensor system-on-chip (2.28 mm × 2.48 mm integrated a humidity sensor, an interface circuit, a digital controller, and an On-Off Keying (OOK wireless transceiver. With low power consumption, i.e., 750 μW without RF operation, the sensitivity of developed sensor chip was experimentally verified in the relative humidity (RH range from 32% to 60%. The response time of the chip was also experimentally verified to be within 5 seconds from RH 36% to RH 64%. As a consequence, the implemented humidity SSoC paves the way toward the an ultra-small sensor system for various applications.

  19. Fabrication of a multiplexed microfluidic system for scaled up production of cross-linked biocatalytic microspheres

    CSIR Research Space (South Africa)

    Mbanjwa, M

    2014-06-01

    Full Text Available the design and fabrication of a multiplexed microfluidic system for producing biocatalytic microspheres. The microfluidic system consists of an array of 10 parallel microfluidic circuits, for simultaneous operation to demonstrate increased production...

  20. Development of inspection data collection and evaluation system for large scale MOX fuel fabrication plant safeguards (3)

    International Nuclear Information System (INIS)

    Kumakura, Shinichi; Masuda, Shoichiro; Iso, Shoko; Hisamatsu, Yoshinori; Kurobe, Hiroko; Nakajima, Shinji

    2015-01-01

    Inspection Data Collection and Evaluation System is the system to store inspection data and operator declaration data collected from various measurement equipment, which is installed in fuel fabrication processes of the large-scale MOX fuel fabrication plant, and to make safeguards evaluation based on Near Real Time Accountancy (NRTA) using these data. Nuclear Material Control Center developed the simulator to simulate fuel fabrication process, in-process material inventory/flow data and the measurement data and the adequacy/impact to the uncertainty of the material balance using the simulation results, such as the facility operation and the operational status, has been reviewed. Following the 34th INMM Japan chapter presentation, the model similar to the real nuclear material accountancy during the fuel fabrication process was simulated and the nuclear material accountancy and its uncertainty (Sigma MUF) have been reviewed. Some findings have been obtained, such as regarding evaluation related indicators for verification under a more realistic accountancy which could be applied by operator. (author)

  1. Yttria-stabilized zirkonia / gadolinium zirconate double-layer plasma-sprayed thermal barrier coating systems (TBCs)

    International Nuclear Information System (INIS)

    Bakan, Emine

    2015-01-01

    Thermal barrier coating (TBC) research and development is driven by the desirability of further increasing the maximum inlet temperature in a gas turbine engine. A number of new top coat ceramic materials have been proposed during the last decades due to limited temperature capability (1200 C) of the state-of-the-art yttria-stabilized zirconia (7 wt. % Y 2 O 3 -ZrO 2 , YSZ) at long term operation. Zirconate pyrochlores of the large lanthanides((Gd → La) 2 Zr 2 O 7 ) have been particularly attractive due to their higher temperature phase stability than that of the YSZ. Nonetheless, the issues related with the implementation of pyrochlores such as low fracture toughness and formation of deleterious interphases with thermally grown oxide (TGO, Al 2 O 3 ) were reported. The implication was the requirement of an interlayer between the pyrochlores and TGO, which introduced double-layer systems to the TBC literature. Furthermore, processability issues of pyrochlores associated with the different evaporation rates of lanthanide oxides and zirconia resulting in unfavorable composition variations in the coatings were addressed in different studies. After all, although the material properties are available, there is a paucity of data in the literature concerning the properties of the coatings made of pyrochlores. From the processability point of view the most reported pyrochlore is La 2 Zr 2 O 7 . Hence, the goal of this research was to investigate plasma-sprayed Gd 2 Zr 2 O 7 (GZO) coatings and YSZ/GZO double-layer TBC systems. Three main topics were examined based on processing, performance and properties: (i) the plasma spray processing of the GZO and its impact on the microstructural and compositional properties of the GZO coatings; (ii) the cycling lifetime of the YSZ/GZO double-layer systems under thermal gradient at a surface temperature of 1400 C; (iii) the properties of the GZO and YSZ coatings such as thermal conductivity, coefficient of thermal expansion as well

  2. Improved Fibroblast Functionalities by Microporous Pattern Fabricated by Microelectromechanical Systems

    OpenAIRE

    Wei, Hongbo; Zhao, Lingzhou; Chen, Bangdao; Bai, Shizhu; Zhao, Yimin

    2014-01-01

    Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10–60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structures with micropore diameters of 10–60 µm did not influence the initial adherent fibroblast number; ...

  3. Design and fabrication of spectrally selective emitter for thermophotovoltaic system by using nano-imprint lithography

    Science.gov (United States)

    Kim, Jong-Moo; Park, Keum-Hwan; Kim, Da-Som; Hwang, Bo-yeon; Kim, Sun-Kyung; Chae, Hee-Man; Ju, Byeong-Kwon; Kim, Young-Seok

    2018-01-01

    Thermophotovoltaic (TPV) systems have attracted attention as promising power generation systems that can directly convert the radiant energy produced by the combustion of fuel into electrical energy. However, there is a fundamental limit of their conversion efficiency due to the broadband distribution of the radiant spectrum. To overcome this problem, several spectrally selective thermal emitter technologies have been investigated, including the fabrication of photonic crystal (PhC) structures. In this paper, we present some design rules based on finite-a difference time-domain (FDTD) simulation results for tungsten (W) PhC emitter. The W 2D PhC was fabricated by a simple nano-imprint lithography (NIL) process, and inductive coupled plasma reactive ion etching (ICP-RIE) with an isotropic etching process, the benefits and parameters of which are presented. The fabricated W PhC emitter showed spectrally selective emission near the infrared wavelength range, and the optical properties varied depending on the size of the nano-patterns. The measured results of the fabricated prototype structure correspond well to the simulated values. Finally, compared with the performance of a flat W emitter, the total thermal emitter efficiency was almost 3.25 times better with the 2D W PhC structure.

  4. Load rate dependence of the mechanical properties of thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Zotov, Nikolay; Eggeler, Gunther [Institut fuer Werkstoffe, Ruhr Universitaet Bochum, 44780 Bochum (Germany); Bartsch, Marion [Institut fuer Werkstoff-Forschung, DLR Koeln, 51147 Koeln (Germany)

    2009-07-01

    Thermal barrier coatings (TBC), composed of yttrium-stabilized zirconia (YSZ) ceramic top coat (TC) and intermetallic NiCoCrAlY bond coat (BC) are commonly used as protective coatings of Ni-based high temperature gas engine components. Nanoindentation techniques are increasingly applied for determining the TBC mechanical properties on a nanometre scale. However, little is known about the load-rate dependence of the mechanical properties, which is important for better understanding of cyclic thermal fatigue experiments. Nanoindentations with different load rates omega were performed on polished cross-sections of TBC, deposited by EB-PVD on IN625 substrates (S), using a XP Nanoindenter (MTS) equipped with Berkovich diamond tip. The Young's modulus (E) of the TC is independent of omega, while E for the BC and the S decreases with omega. The hardness (H) of the TC and the BC increases, while H for the S decreases with omega. From the dependence of H on omega, creep power-law exponents c = 0.24(11) and c = 0.023(6) for the TC and the BC were determined. For all TBC components, a decrease with omega of the power-law exponents n and m, describing the loading and unloading nanoindentation curves, is observed.

  5. New polymorphous computing fabric

    International Nuclear Information System (INIS)

    Wolinski, Christophe; Gokhale, Maya; McCabe, Kevin P.

    2002-01-01

    This paper introduces a new polymorphous computing Fabric well suited to DSP and Image Processing and describes its implementation on a Configurable System on a Chip (CSOC). The architecture is highly parameterized and enables customization of the synthesized Fabric to achieve high performance for a specific class of application. For this reason it can be considered to be a generic model for hardware accelerator synthesis from a high level specification. Another important innovation is the Fabric uses a global memory concept, which gives the host processor random access to all the variables and instructions on the Fabric. The Fabric supports different computing models including MIMD, SPMD and systolic flow and permits dynamic reconfiguration. We present a specific implementation of a bank of FIR filters on a Fabric composed of 52 cells on the Altera Excalibur ARM running at 33 MHz. The theoretical performance of this Fabric is 1.8 GMACh. For the FIR application we obtain 1.6 GMAC/s real performance. Some automatic tools have been developed like the tool to provide a host access utility and assembler.

  6. Design to fabrication integration and material craftsmanship - A performance driven stone architecture design system based on material, structural and fabrication constraints and criteria

    NARCIS (Netherlands)

    Mostafavi, S.; Tanti, M.

    2014-01-01

    This paper presents a computational design methodology through describing of a case study on stone building system. In addition to establishing a performance driven form-finding methodology, the objective is to redefine local craftsmanship methods as industrial fabrication techniques in order to

  7. Interfacing robotics with plutonium fuel fabrication

    International Nuclear Information System (INIS)

    Bowen, W.W.; Moore, F.W.

    1986-01-01

    Interfacing robotic systems with nuclear fuel fabrication processes resulted in a number of interfacing challenges. The system not only interfaces with the fuel process, but must also interface with nuclear containment, radiation control boundaries, criticality control restrictions, and numerous other safety systems required in a fuel fabrication plant. The robotic system must be designed to allow operator interface during maintenance and recovery from an upset as well as normal operations

  8. Internal accounting system for feed materials in the plutonium fuel fabrication complex at Cadarache

    International Nuclear Information System (INIS)

    Arnal, T.; Guillet, H.

    1976-01-01

    The internal accounting system of the Fabrication and Radiometallurgical Inspection Service (SFER) is basically designed to meet national and international requirements for nuclear materials accountancy as applied to feed materials. The authors discuss the principles underlying this accounting system for the case of the Plutonium Fuel Assembly Fabrication Complex at Cadarache. The sphere of application of the system covers more than 200 work stations and approximately 100 different materials. Some 20000 movements of feed materials per year represent transfers of a cumulative mass much greater than one ton of fissile material. A data processing system has therefore become essential in order to ensure the rapid and reliable acquisition of accounting data relating to these movements. The authors describe the system (definition of stations and material codes, description of supporting facilities used) and discuss the mode of acquisition with particular reference to relative speed of action. In conclusion, the authors indicate that the system offers interesting possibilities, in addition to its original purpose, in the following areas: Preparation of material balances; compliance with safety regulations to avert the risk of criticality; discouragement of possible diversion. (author)

  9. Work plan for the fabrication of the radioisotope thermoelectric generator transportation system package mounting

    International Nuclear Information System (INIS)

    Satoh, J.A.

    1994-01-01

    The Radioisotope Thermoelectric Generator (RTG) has available a dedicated system for the transportation of RTG payloads. The RTG Transportation System (System 100) is comprised of four systems; the Package (System 120), the Semi-trailer (System 140), the Gas Management (System 160), and the Facility Transport (System 180). This document provides guidelines on the fabrication, technical requirements, and quality assurance of the Package Mounting (Subsystem 145), part of System 140. The description follows the Development Control Requirements of WHC-CM-6-1, EP 2.4, Rev. 3

  10. An Ethology of Urban Fabric(s)

    DEFF Research Database (Denmark)

    Fritsch, Jonas; Thomsen, Bodil Marie Stavning

    2014-01-01

    The article explores a non-metaphorical understanding of urban fabric(s), shifting the attention from a bird’s eye perspective to the actual, textural manifestations of a variety of urban fabric(s) to be studied in their real, processual, ecological and ethological complexity within urban life. We...... effectuate this move by bringing into resonance a range of intersecting fields that all deal with urban fabric(s) in complementary ways (interaction design and urban design activism, fashion, cultural theory, philosophy, urban computing)....

  11. AFM lithography of aluminum for fabrication of nanomechanical systems

    DEFF Research Database (Denmark)

    Davis, Zachary James; Abadal, G.; Hansen, Ole

    2003-01-01

    Nanolithography by local anodic oxidation of surfaces using atomic force microscopy (AFM) has proven to be more reproducible when using dynamic, non-contact mode. Hereby, the tip/sample interaction forces are reduced dramatically compared to contact mode, and thus tip wear is greatly reduced....... Anodic oxidation of Al can be used for fabricating nanomechanical systems, by using the Al oxide as a highly selective dry etching mask. In our experiments, areas as large as 2 mum x 3 mum have been oxidized repeatedly without any sign of tip-wear. Furthermore, line widths down to 10 nm have been...

  12. Regolith Derived Heat Shield for Planetary Body Entry and Descent System with In Situ Fabrication

    Science.gov (United States)

    Hogue, Michael D.; Meuller, Robert P.; Sibille, Laurent; Hintze, Paul E.; Rasky, Daniel J.

    2012-01-01

    This NIAC project investigated an innovative approach to provide heat shield protection to spacecraft after launch and prior to each EDL thus potentially realizing significant launch mass savings. Heat shields fabricated in situ can provide a thermal-protection system for spacecraft that routinely enter a planetary atmosphere. By fabricating the heat shield with space resources from materials available on moons and asteroids, it is possible to avoid launching the heat-shield mass from Earth. Regolith has extremely good insulating properties and the silicates it contains can be used in the fabrication and molding of thermal-protection materials. Such in situ developed heat shields have been suggested before by Lewis. Prior research efforts have shown that regolith properties can be compatible with very-high temperature resistance. Our project team is highly experienced in regolith processing and thermal protection systems (TPS). Routine access to space and return from any planetary surface requires dealing with heat loads experienced by the spacecraft during reentry. Our team addresses some of the key issues with the EDL of human-scale missions through a highly innovative investigation of heat shields that can be fabricated in space by using local resources on asteroids and moons. Most space missions are one-way trips, dedicated to placing an asset in space for economical or scientific gain. However, for human missions, a very-reliable heat-shield system is necessary to protect the crew from the intense heat experienced at very high entry velocities of approximately 11 km/s at approximately Mach 33 (Apollo). For a human mission to Mars, the return problem is even more difficult, with predicted velocities of up to 14 km/s, at approximately Mach 42 at the Earth-atmosphere entry. In addition to human return, it is very likely that future space-travel architecture will include returning cargo to the Earth, either for scientific purposes or for commercial reasons

  13. Design, Fabrication, and Shakeout Testing of ATALANTE Dissolver Off-Gas Sorbent-Based Capture System

    International Nuclear Information System (INIS)

    Walker Jr, Joseph Franklin; Jubin, Robert Thomas; Jordan, Jacob A.; Bruffey, Stephanie H.

    2015-01-01

    A sorbent-based capture system designed for integration into the existing dissolver off-gas (DOG) treatment system at the ATelier Alpha et Laboratoires pour ANalyses, Transuraniens et Etudes de retraitement (ATALANTE) facility has been successfully designed and fabricated and has undergone shakeout testing. Discussions with personnel from the ATALANTE facility provided guidance that was used for the design. All components for this system were specified, procured, and received on site at Oak Ridge National Laboratory (ORNL). The system was then fabricated and tested at ORNL to verify operation. Shakeout testing resulted in a simplified system. This system should be easily installed into the existing facility and should be straightforward to operate during future experimental testing. All parts were selected to be compatible with ATALANTE power supplies, space requirements, and the existing DOG treatment system. Additionally, the system was demonstrated to meet all of four design requirements. These include (1) a dissolver off-gas flow rate of ?100 L/h (1.67 L/min), (2) an external temperature of ?50°C for all system components placed in the hot cell, (3) a sorbent bed temperature of ~150°C, and (4) a gas temperature of ~150°C upon entry into the sorbent bed. The system will be ready for shipment and installation in the existing DOG treatment system at ATALANTE in FY 2016.

  14. INTEGRATED PROTECTIVE FABRIC SYSTEM (IPFS) PHASE III PROGRAM: AEROSOL PROTECTION REPORT

    Science.gov (United States)

    2017-08-16

    control. It consists of a woven nylon/cotton outer shell ripstop fabric with a durable water repellent finish (Quarpel) with a hung liner comprised of...challenge, most were made using DOP. The TSI 3160 is equipped with two TSI Model 3772 Condensation Particle Counters (CPCs). The Model 3772 CPC detects ...results were used to demonstrate that any penetration measured through the swatch materials was not attributed to leakage or erroneous system

  15. Optimization of APS-ZrO{sub 2}-thermal barrier coatings by variations of creep strength and interface roughness; Optimierung von APS-ZrO{sub 2}-Waermedaemmschichten durch Variationen der Kriechfestigkeit und der Grenzflaechenrauhigkeit

    Energy Technology Data Exchange (ETDEWEB)

    Schweda, Mario

    2011-07-01

    Gas turbines operate at combustion chamber temperatures up to 1400 C. Therefore the blades and the combustion chamber lining, which consist of Ni-superalloys for highest loads, are coated with a thermal barrier coating (TBC) of zirconium oxide and an underlying oxidation protection coating of MCrAlY-alloys (M=Ni, Co). At high temperature the MCrAlY-coating oxidizes and an Al{sub 2}O{sub 3}-scale (thermally grown oxide, TGO) forms between MCrAlY-coating and TBC, what constrains the oxidation of the base material. At plasma sprayed TBCs, the MCrAlY-coating provides a bond coat (BC) for the TBC at the same time and therefore is roughened by sandblasting before the deposition of the TBC. By the growth of the Al{sub 2}O{sub 3}-scale and the start up and run down of the gas turbine, stresses arise in the TBC, which lead to lateral crack formation in the field of the TBC-BC-interface and finally to the spallation of the TBC. Thereby other parts of the turbine can be damaged, what causes high costs. Therefrom the aim is to delay the crack growth as strong as possible or rather to maximize the lifetime of the TBC. For this purpose the material properties of the coating components have to be optimized. In the present work, the influence of creep strength of BC and TGO and the influence of TBC-BC-interface-roughness on the lifetime and damage evolution of plasma sprayed ZrO{sub 2}-TBCs are investigated. To determine the lifetime, cylindrical specimens with plasma sprayed ZrO{sub 2}-TBC were produced and thermally cycled with a minimum and maximum temperature of 60 C and 1050 C and a dwell time at maximal temperature of 2h. To exclude the interdiffusion and thermal mismatch between BC and Ni-superalloy, a model system was used: The Ni-superalloy was left and the substrate material consists completely of a BC-like FeCrAlY-alloy. The model system was simulated by the project partner TU Braunschweig with the FE-method. The TBC-BC-interface-roughness was abstracted by a 2

  16. Method of fabricating a cooled electronic system

    Science.gov (United States)

    Chainer, Timothy J; Gaynes, Michael A; Graybill, David P; Iyengar, Madhusudan K; Kamath, Vinod; Kochuparambil, Bejoy J; Schmidt, Roger R; Schultz, Mark D; Simco, Daniel P; Steinke, Mark E

    2014-02-11

    A method of fabricating a liquid-cooled electronic system is provided which includes an electronic assembly having an electronics card and a socket with a latch at one end. The latch facilitates securing of the card within the socket. The method includes providing a liquid-cooled cold rail at the one end of the socket, and a thermal spreader to couple the electronics card to the cold rail. The thermal spreader includes first and second thermal transfer plates coupled to first and second surfaces on opposite sides of the card, and thermally conductive extensions extending from end edges of the plates, which couple the respective transfer plates to the liquid-cooled cold rail. The extensions are disposed to the sides of the latch, and the card is securable within or removable from the socket using the latch without removing the cold rail or the thermal spreader.

  17. Alternative fabrication scheme to study effects of rework of nonconforming products and delayed differentiation on a multiproduct supply-chain system

    Directory of Open Access Journals (Sweden)

    Yuan-Shyi Peter Chiu

    2017-07-01

    Full Text Available This study uses an alternative fabrication scheme to study the effect of rework of nonconforming items and delayed differentiation on a multiproduct supply-chain system. Traditional economic production quantity model focuses on a single-product inventory system where all products made are assumed to be perfect quality and finished products are issued continuously. To increase machine utilization, lower quality costs in production, and reflect the real-world vendor-buyer integrated systems Chiu et al. (2016a [Chiu, Y-S.P., Kuo, J-S., Chiu, S. W., Hsieh, Y-T. (2016a. Effect of delayed differentiation on a multiproduct vendor–buyer integrated inventory system with rework. Advances in Production Engineering & Management, 11(4, 333-344.] employed a single-machine two-stage production scheme to study the effects of rework and delayed differentiation on a multi-product supply-chain system. With the intention of further reducing fabrication cycle time, this study considers an alternative two-machine two-stage fabrication scheme to re-explore the problem in Chiu et al. (2016a. Machine one solely produces all common parts for multiple end products. Then, machine two fabricates the customized multiproduct using a common cycle time strategy. Through the use of mathematical modeling and analyses, the optimal production cycle length and distribution policy are derived. Numerical examples are provided to demonstrate practical usage of the research results, and show its significant benefit in reducing fabrication cycle time compared to that obtained from prior studies that used different schemes.

  18. Yttria-stabilized zirkonia / gadolinium zirconate double-layer plasma-sprayed thermal barrier coating systems (TBCs)

    Energy Technology Data Exchange (ETDEWEB)

    Bakan, Emine

    2015-07-01

    Thermal barrier coating (TBC) research and development is driven by the desirability of further increasing the maximum inlet temperature in a gas turbine engine. A number of new top coat ceramic materials have been proposed during the last decades due to limited temperature capability (1200 C) of the state-of-the-art yttria-stabilized zirconia (7 wt. % Y{sub 2}O{sub 3}-ZrO{sub 2}, YSZ) at long term operation. Zirconate pyrochlores of the large lanthanides((Gd → La){sub 2}Zr{sub 2}O{sub 7}) have been particularly attractive due to their higher temperature phase stability than that of the YSZ. Nonetheless, the issues related with the implementation of pyrochlores such as low fracture toughness and formation of deleterious interphases with thermally grown oxide (TGO, Al{sub 2}O{sub 3}) were reported. The implication was the requirement of an interlayer between the pyrochlores and TGO, which introduced double-layer systems to the TBC literature. Furthermore, processability issues of pyrochlores associated with the different evaporation rates of lanthanide oxides and zirconia resulting in unfavorable composition variations in the coatings were addressed in different studies. After all, although the material properties are available, there is a paucity of data in the literature concerning the properties of the coatings made of pyrochlores. From the processability point of view the most reported pyrochlore is La{sub 2}Zr{sub 2}O{sub 7}. Hence, the goal of this research was to investigate plasma-sprayed Gd{sub 2}Zr{sub 2}O{sub 7} (GZO) coatings and YSZ/GZO double-layer TBC systems. Three main topics were examined based on processing, performance and properties: (i) the plasma spray processing of the GZO and its impact on the microstructural and compositional properties of the GZO coatings; (ii) the cycling lifetime of the YSZ/GZO double-layer systems under thermal gradient at a surface temperature of 1400 C; (iii) the properties of the GZO and YSZ coatings such as

  19. Comparison of Extruder Systems for 3D Printer Filament Fabrication

    Science.gov (United States)

    Ramirez, Adriana

    Additive Manufacturing (AM) has grown in popularity over the past thirty years, due to its versatility, short design to product cycle, and capability to fabricate complex geometries, which cannot otherwise be produced. There exist several platforms that are able to print objects composed of different materials, making this technology significant in different fields such as: automotive, aerospace, medical, electronics, amongst others. Though several types of AM technologies are available, the expiration of the patents on fused deposition modeling (FDM) in 2009 has led to a widespread use of this platform in academia and home use settings. Widespread use of FDM-type AM platforms has led to a demand to fabricate feedstock materials for this AM platform. Particularly, in the home do it yourself (DIY) community there has been a widespread interest for users to manufacture their own feedstock filament leading to a large growth in home-use extrusion systems. The low cost of these desktop-grade systems has also made them attractive to academics, but there has not been a widespread effort into determining the efficacy of these small scale extrusion systems as compared to industrial quality extruders which are typically used to manufacture feedstock for FDM platforms. The aim of this study was to compare two extrusion processes: 1) a desktop grade single-screw extruder; and 2) an industrial scale twin-screw extruder. In order to understand differences between their performance and quality of mixing, a rubberized blend of acrylonitrile butadiene styrene (ABS) mixed with styrene ethylene butylene styrene with a maleic anhydride graft (SEBS-g-MA) at different ratios was compounded on each extrusion system. Melt flow index, and mechanical properties were compared. In addition, a raster pattern sensitivity study was performed to evaluate the effect of the extruder system on 3D printed objects. Finally, scanning electron microscopy (SEM) was used to examine the fracture surfaces

  20. Development of an engineered safeguards system concept for a mixed-oxide fuel fabrication facility

    International Nuclear Information System (INIS)

    Chapman, L.D.; de Montmollin, J.M.; Deveney, J.E.; Fienning, W.C.; Hickman, J.W.; Watkins, L.D.; Winblad, A.E.

    1976-08-01

    An initial concept of an Engineered Safeguards System for a representative commercial mixed-oxide fuel fabrication facility is presented. Computer simulation techniques for evaluation and further development of the concept are described. An outline of future activity is included

  1. Accuracy evaluation of metal copings fabricated by computer-aided milling and direct metal laser sintering systems.

    Science.gov (United States)

    Park, Jong-Kyoung; Lee, Wan-Sun; Kim, Hae-Young; Kim, Woong-Chul; Kim, Ji-Hwan

    2015-04-01

    To assess the marginal and internal gaps of the copings fabricated by computer-aided milling and direct metal laser sintering (DMLS) systems in comparison to casting method. Ten metal copings were fabricated by casting, computer-aided milling, and DMLS. Seven mesiodistal and labiolingual positions were then measured, and each of these were divided into the categories; marginal gap (MG), cervical gap (CG), axial wall at internal gap (AG), and incisal edge at internal gap (IG). Evaluation was performed by a silicone replica technique. A digital microscope was used for measurement of silicone layer. Statistical analyses included one-way and repeated measure ANOVA to test the difference between the fabrication methods and categories of measured points (α=.05), respectively. The mean gap differed significantly with fabrication methods (P<.001). Casting produced the narrowest gap in each of the four measured positions, whereas CG, AG, and IG proved narrower in computer-aided milling than in DMLS. Thus, with the exception of MG, all positions exhibited a significant difference between computer-aided milling and DMLS (P<.05). Although the gap was found to vary with fabrication methods, the marginal and internal gaps of the copings fabricated by computer-aided milling and DMLS fell within the range of clinical acceptance (<120 µm). However, the statistically significant difference to conventional casting indicates that the gaps in computer-aided milling and DMLS fabricated restorations still need to be further reduced.

  2. Micro Machining Enhances Precision Fabrication

    Science.gov (United States)

    2007-01-01

    Advanced thermal systems developed for the Space Station Freedom project are now in use on the International Space Station. These thermal systems employ evaporative ammonia as their coolant, and though they employ the same series of chemical reactions as terrestrial refrigerators, the space-bound coolers are significantly smaller. Two Small Business Innovation Research (SBIR) contracts between Creare Inc. of Hanover, NH and Johnson Space Center developed an ammonia evaporator for thermal management systems aboard Freedom. The principal investigator for Creare Inc., formed Mikros Technologies Inc. to commercialize the work. Mikros Technologies then developed an advanced form of micro-electrical discharge machining (micro-EDM) to make tiny holes in the ammonia evaporator. Mikros Technologies has had great success applying this method to the fabrication of micro-nozzle array systems for industrial ink jet printing systems. The company is currently the world leader in fabrication of stainless steel micro-nozzles for this market, and in 2001 the company was awarded two SBIR research contracts from Goddard Space Flight Center to advance micro-fabrication and high-performance thermal management technologies.

  3. Design and fabrication of radiation shielded laser ablation ICP-MS system

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Yeong Keong; Han, Sun Ho; Park, Soon Dal; Park, Yang Soon; Jee, Kwang Yong; Kim, Won Ho

    2006-09-15

    In relation to high burn up and extended fuel cycle for the fuel cycle efficiency, we need to take chemical analysis of spent nuclear fuel for the integrity of nuclear fuel at high burn up. to measure the isotopic distribution of fission product in a high burn up nuclear fuel, radiation shielded laser ablation system was designed and fabricated. By probing the sample with a laser beam, micro sampling system for the mass analyzer was successfully developed. This report describes the structural design and the function of developed radiation shielded LA system. This system will be used for the analysis of isotopic distribution from core to rim of a spent nuclear fuel prepared from the hot-cell in PIE facility and/or an irradiated fuel from research reactor.

  4. Fabrication of a Sludge-Conditioning System for processing legacy wastes from the Gunite and Associated Tanks

    International Nuclear Information System (INIS)

    Randolph, J.D.; Lewis, B.E.; Farmer, J.R.; Johnson, M.A.

    2000-01-01

    The Sludge Conditioning System (SCS) for the Gunite and Associated Tanks (GAATs) is designed to receive, monitor, characterize and process legacy waste materials from the South Tank Farm tanks in preparation for final transfer of the wastes to the Melton Valley Storage Tanks (MVSTs), which are located at Oak Ridge National Laboratory. The SCS includes (1) a Primary Conditioning System (PCS) Enclosure for sampling and particle size classification, (2) a Solids Monitoring Test Loop (SMTL) for slurry characterization, (3) a Waste Transfer Pump to retrieve and transfer waste materials from GAAT consolidation tank W-9 to the MVSTs, (4) a PulsAir Mixing System to provide mixing of consolidated sludges for ease of retrieval, and (5) the interconnecting piping and valving. This report presents the design, fabrication, cost, and fabrication schedule information for the SCS

  5. Systems and Methods for Fabricating Structures Including Metallic Glass-Based Materials Using Low Pressure Casting

    Science.gov (United States)

    Hofmann, Douglas C. (Inventor); Kennett, Andrew (Inventor)

    2018-01-01

    Systems and methods to fabricate objects including metallic glass-based materials using low-pressure casting techniques are described. In one embodiment, a method of fabricating an object that includes a metallic glass-based material includes: introducing molten alloy into a mold cavity defined by a mold using a low enough pressure such that the molten alloy does not conform to features of the mold cavity that are smaller than 100 microns; and cooling the molten alloy such that it solidifies, the solid including a metallic glass-based material.

  6. Tritium Systems Test Assembly: design for major device fabrication review

    International Nuclear Information System (INIS)

    Anderson, J.L.; Sherman, R.H.

    1977-06-01

    This document has been prepared for the Major Device Fabrication Review for the Tritium Systems Test Assembly (TSTA). The TSTA is dedicated to the development, demonstration, and interfacing of technologies related to the deuterium-tritium fuel cycle for fusion reactor systems. The principal objectives for TSTA are: (a) demonstrate the fuel cycle for fusion reactor systems; (b) develop test and qualify equipment for tritium service in the fusion program; (c) develop and test environmental and personnel protective systems; (d) evaluate long-term reliability of components; (e) demonstrate long-term safe handling of tritium with no major releases or incidents; and (f) investigate and evaluate the response of the fuel cycle and environmental packages to normal, off-normal, and emergency situations. This document presents the current status of a conceptual design and cost estimate for TSTA. The total cost to design, construct, and operate TSTA through FY-1981 is estimated to be approximately $12.2 M

  7. Feedback System Control Optimized Electrospinning for Fabrication of an Excellent Superhydrophobic Surface.

    Science.gov (United States)

    Yang, Jian; Liu, Chuangui; Wang, Boqian; Ding, Xianting

    2017-10-13

    Superhydrophobic surface, as a promising micro/nano material, has tremendous applications in biological and artificial investigations. The electrohydrodynamics (EHD) technique is a versatile and effective method for fabricating micro- to nanoscale fibers and particles from a variety of materials. A combination of critical parameters, such as mass fraction, ratio of N, N-Dimethylformamide (DMF) to Tetrahydrofuran (THF), inner diameter of needle, feed rate, receiving distance, applied voltage as well as temperature, during electrospinning process, to determine the morphology of the electrospun membranes, which in turn determines the superhydrophobic property of the membrane. In this study, we applied a recently developed feedback system control (FSC) scheme for rapid identification of the optimal combination of these controllable parameters to fabricate superhydrophobic surface by one-step electrospinning method without any further modification. Within five rounds of experiments by testing totally forty-six data points, FSC scheme successfully identified an optimal parameter combination that generated electrospun membranes with a static water contact angle of 160 degrees or larger. Scanning electron microscope (SEM) imaging indicates that the FSC optimized surface attains unique morphology. The optimized setup introduced here therefore serves as a one-step, straightforward, and economic approach to fabricate superhydrophobic surface with electrospinning approach.

  8. Fabrication of recyclable superhydrophobic cotton fabrics

    Science.gov (United States)

    Han, Sang Wook; Park, Eun Ji; Jeong, Myung-Geun; Kim, Il Hee; Seo, Hyun Ook; Kim, Ju Hwan; Kim, Kwang-Dae; Kim, Young Dok

    2017-04-01

    Commercial cotton fabric was coated with SiO2 nanoparticles wrapped with a polydimethylsiloxane (PDMS) layer, and the resulting material surface showed a water contact angle greater than 160°. The superhydrophobic fabric showed resistance to water-soluble contaminants and maintained its original superhydrophobic properties with almost no alteration even after many times of absorption-washing cycles of oil. Moreover, superhydrophobic fabric can be used as a filter to separate oil from water. We demonstrated a simple method of fabrication of superhydrophobic fabric with potential interest for use in a variety of applications.

  9. Remote mixed oxide fabrication facility development. Volume 2. State-of-the-art review of remote maintenance system technology

    International Nuclear Information System (INIS)

    Horgos, R.M.; Masch, M.L.

    1979-06-01

    This report provides a state-of-the-art review of remote systems technology, which includes manipulators, process connectors, vision systems and specialized process systems. A proposed mixed oxide fuel fabrication facility was reviewed and evaluated for identification of major remote maintenance and repair tasks. The technological areas were evaluated on the basis of their suitability or applicability for remote maintenance and repair of a proposed fully remote operating mixed oxide fuel fabrication facility. A technological base exists from which the design criteria for a reliable, remote operating facility can be established. Commercially available systems and components, along with those remote technologies now in development, will require modifications to adapt them to specific plant designs and requirements

  10. Design, fabrication, operation and modification of a glove box adaptable microwave heating system

    Energy Technology Data Exchange (ETDEWEB)

    Mallik, G K; Gautam, V K; Shivashankaran, G; Behere, P G; Mohan, Anand; Bhargava, V K; Kamath, H S [Advanced Fuel Fabrication Facility, Bhabha Atomic Research Centre, Tarapur (India)

    1999-01-01

    The microwave heating techniques have enormous potential to improve the processing conditions for many radiochemical and radio-metallurgical processes. An update review on the various aspects of development and fabrication of an indigenous microwave heating system and its adaptation to the glove box has been reported in this paper. (author) 3 refs.

  11. Design of an engineered safeguards system for a mixed-oxide fuel fabrication facility

    International Nuclear Information System (INIS)

    Winblad, A.E.; McKnight, R.P.; Fienning, W.C.; Fenchel, B.R.

    1977-06-01

    Several Engineered Safeguards System concepts and designs are described that provide increased protection against a wide spectrum of adversary threats. An adversary sequence diagram that outlines all possible adversary paths through the safeguards elements in a mixed-oxide fuel fabrication facility is shown. An example of a critical adversary path is given

  12. Nuclear Fabrication Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Levesque, Stephen [EWI, Columbus, OH (United States)

    2013-04-05

    This report summarizes the activities undertaken by EWI while under contract from the Department of Energy (DOE) Office of Nuclear Energy (NE) for the management and operation of the Nuclear Fabrication Consortium (NFC). The NFC was established by EWI to independently develop, evaluate, and deploy fabrication approaches and data that support the re-establishment of the U.S. nuclear industry: ensuring that the supply chain will be competitive on a global stage, enabling more cost-effective and reliable nuclear power in a carbon constrained environment. The NFC provided a forum for member original equipment manufactures (OEM), fabricators, manufacturers, and materials suppliers to effectively engage with each other and rebuild the capacity of this supply chain by : Identifying and removing impediments to the implementation of new construction and fabrication techniques and approaches for nuclear equipment, including system components and nuclear plants. Providing and facilitating detailed scientific-based studies on new approaches and technologies that will have positive impacts on the cost of building of nuclear plants. Analyzing and disseminating information about future nuclear fabrication technologies and how they could impact the North American and the International Nuclear Marketplace. Facilitating dialog and initiate alignment among fabricators, owners, trade associations, and government agencies. Supporting industry in helping to create a larger qualified nuclear supplier network. Acting as an unbiased technology resource to evaluate, develop, and demonstrate new manufacturing technologies. Creating welder and inspector training programs to help enable the necessary workforce for the upcoming construction work. Serving as a focal point for technology, policy, and politically interested parties to share ideas and concepts associated with fabrication across the nuclear industry. The report the objectives and summaries of the Nuclear Fabrication Consortium

  13. Development of automation and remotisation systems for fabrication of (Th-233U)O2 MOX fuel for AHWR

    International Nuclear Information System (INIS)

    Saraswat, Anupam; Danny, K.M.; Chakraborty, S.; Somayajulu, P.S.; Kumar, Arun; Mittal, R.; Prasad, R.S.; Mahule, K.N.; Panda, S.; Jayarajan, K.

    2011-01-01

    To meet the ever increasing power requirement of India, country is planning to utilize its large thorium reserves for the third stage of nuclear power program based on Thorium-Uranium 233 fuel in A.H.W.R. Although there are many advantages of (Th- 233 U)O 2 fuel cycle, presence of radiological hazards due to the presence of 1000-2000 ppm level of 232 U in the 233 U fuel and inertness of ThO 2 makes handling and fabrication of fuel difficult. The associated high alpha and gamma activity demands high level of automation and remote handling in alpha tight hot cells. To demonstrate automation and remotisation in (Th- 233 U)O 2 fuel fabrication, a mock up facility is being set up at BARC. This facility shall develop automation systems required for remote fuel fabrication in a simulated hot cell environment. There are many innovative schemes and systems being developed like integrated powder pellet system, remote viewing system for hot cell application etc. Low visibility inside the hot cell has always been a problem for the operator. To overcome this problem a remote viewing system has been developed by which entire hot cell area can be scanned with the use of a joystick and the display can be seen on a LCD monitor. The viewing system is made up of radiation resistant optics which can work even in high gamma fields. It consists of objective end assembly which is used to scan the hot cell area with the help of prism doublets and drive mechanism for capturing full 360 deg solid angle view. There is a Galilean telescope and focusing system used for focusing images of distant objects. Drive mechanism can be controlled by the joystick available to the operator. System has a high resolution CCD display and camera which gives a clear display of objects lying inside the hot cell area. Integrated powder pellet system is being developed for fabrication of MOX pellets from feed powder. This will be automated system which will take input in the form of MOX powder and convert it

  14. Environmental/Thermal Barrier Coatings for Ceramic Matrix Composites: Thermal Tradeoff Studies

    Science.gov (United States)

    Murthy, Pappu L. M.; Brewer, David; Shah, Ashwin R.

    2007-01-01

    Recent interest in environmental/thermal barrier coatings (EBC/TBCs) has prompted research to develop life-prediction methodologies for the coating systems of advanced high-temperature ceramic matrix composites (CMCs). Heat-transfer analysis of EBC/TBCs for CMCs is an essential part of the effort. It helps establish the resulting thermal profile through the thickness of the CMC that is protected by the EBC/TBC system. This report documents the results of a one-dimensional analysis of an advanced high-temperature CMC system protected with an EBC/TBC system. The one-dimensional analysis was used for tradeoff studies involving parametric variation of the conductivity; the thickness of the EBC/TBCs, bond coat, and CMC substrate; and the cooling requirements. The insight gained from the results will be used to configure a viable EBC/TBC system for CMC liners that meet the desired hot surface, cold surface, and substrate temperature requirements.

  15. Development and Life Prediction of Erosion Resistant Turbine Low Conductivity Thermal Barrier Coatings

    Science.gov (United States)

    Zhu, Dongming; Miller, Robert A.; Kuczmarski, Maria A.

    2010-01-01

    Future rotorcraft propulsion systems are required to operate under highly-loaded conditions and in harsh sand erosion environments, thereby imposing significant material design and durability issues. The incorporation of advanced thermal barrier coatings (TBC) in high pressure turbine systems enables engine designs with higher inlet temperatures, thus improving the engine efficiency, power density and reliability. The impact and erosion resistance of turbine thermal barrier coating systems are crucial to the turbine coating technology application, because a robust turbine blade TBC system is a prerequisite for fully utilizing the potential coating technology benefit in the rotorcraft propulsion. This paper describes the turbine blade TBC development in addressing the coating impact and erosion resistance. Advanced thermal barrier coating systems with improved performance have also been validated in laboratory simulated engine erosion and/or thermal gradient environments. A preliminary life prediction modeling approach to emphasize the turbine blade coating erosion is also presented.

  16. Fabrication of optical fiber micro(and nano)-optical and photonic devices and components, using computer controlled spark thermo-pulling system

    International Nuclear Information System (INIS)

    Fatemi, H.; Mosleh, A.; Pashmkar, M.; Khaksar Kalati, A.

    2007-01-01

    Fabrication of optical fiber Micro (and Nano)-Optical component and devices, as well as, those applicable for photonic purposes are described. It is to demonstrate the practical capabilities and characterization of the previously reported Computer controlled spark thermo-pulling fabrication system.

  17. Mechanical Properties of Layered La2Zr2O7 Thermal Barrier Coatings

    Science.gov (United States)

    Guo, Xingye; Li, Li; Park, Hyeon-Myeong; Knapp, James; Jung, Yeon-Gil; Zhang, Jing

    2018-04-01

    Lanthanum zirconate (La2Zr2O7) has been proposed as a promising thermal barrier coating (TBC) material due to its low thermal conductivity and high stability at high temperatures. In this work, both single and double-ceramic-layer (DCL) TBC systems of La2Zr2O7 and 8 wt.% yttria-stabilized zirconia (8YSZ) were prepared using air plasma spray (APS) technique. The thermomechanical properties and microstructure were investigated. Thermal gradient mechanical fatigue (TGMF) tests were applied to investigate the thermal cycling performance. The results showed that DCL La2Zr2O7 + 8YSZ TBC samples lasted fewer cycles compared with single-layered 8YSZ TBC samples in TGMF tests. This is because DCL La2Zr2O7 TBC samples had higher residual stress during the thermal cycling process, and their fracture toughness was lower than that of 8YSZ. Bond strength test results showed that 8YSZ TBC samples had higher bond strength compared with La2Zr2O7. The erosion rate of La2Zr2O7 TBC samples was higher than that of 8YSZ samples, due to the lower critical erodent velocity and fracture toughness of La2Zr2O7. DCL porous 8YSZ + La2Zr2O7 had a lower erosion rate than other SCL and DCL La2Zr2O7 coatings, suggesting that porous 8YSZ serves as a stress-relief buffer layer.

  18. The impact of changes in the milk payment system and season on the hygienic quality of milk

    Directory of Open Access Journals (Sweden)

    Vedat PAŠIĆ

    2016-09-01

    Full Text Available The aims of this paper were to investigate the impact of changes in the milk payment system and the season on the hygienic quality of raw milk. The bulk cow’s milk samples were collected throughout the whole area of Bosnia and Herzegovina over the period of four years (2010-2013, from farms that deliver milk to the dairy industry. The total bacterial count (TBC was analysed in 52,999 milk samples and the somatic cell count (SCC in 53,363 milk samples. The results of the research showed that the proportion of bulk milk with the SCC < 300,000 mL-1 significantly increased in the observed period, as well as the proportion of farms that produce milk of EU quality (P < 0.05. The season had a significant effect (P < 0.05 on the SCC; in April the proportion of bulk milk with SCC < 300,000 mL-1 was significantly higher (P < 0.05. A significant increase (P < 0.05 in the proportion of milk with the TBC < 200,000 cfu∙mL -1 was perceived, as well as the proportion of farms which deliver that type of milk (P < 0.05. A Significant lower (P < 0.05 proportion of milk in the summer period with TBC < 200,000 cfu∙mL-1 was determined. It can be concluded that consistent appliance of regulations which determine the quality of milk, leads to the improvement of the hygienic quality of redeemed milk, as illustrated by the case of Bosnia and Herzegovina. This kind of milk payment system is important for both, the higher economic benefit of farms and the dairy processing industry.

  19. Fabrication and modeling of narrow capillaries for vacuum system gas inlets

    DEFF Research Database (Denmark)

    Quaade, Ulrich; Jensen, Søren; Hansen, Ole

    2005-01-01

    Micrometer-sized cylindrical capillaries with well-controlled dimensions are fabricated using deep reactive ion etching. The flow through the capillaries is experimentally characterized for varying pressures, temperatures, and diameters. For the parameters used, it is shown that the Knudsen numbe...... is in the intermediate flow regime, and Knudsen's expression for the flow fit the data well. The flow properties of the capillaries make them ideal for introducing gas into vacuum systems and in particular mass spectrometers. ©2005 American Institute of Physics...

  20. Fabrication and characterisation of fabric supercapacitor

    OpenAIRE

    Yong, Sheng

    2016-01-01

    Fabric supercapacitor is a flexible electrochemical device for energy storage application. It is designed to power up flexible electronic systems used for, for example, information sensing, data computation and communication. The development of a flexible supercapacitor is important for e-textiles since supercapacitor can achieve higher energy density than a standard parallel plate capacitor and a larger power density compared with a battery. This research area is currently facing barriers on...

  1. Laser deposition of coatings for aeronautical and industrials turbine blades

    Energy Technology Data Exchange (ETDEWEB)

    Teleginski, V. [Instituto Federal de Sao Paulo (IFSP), SP (Brazil); Silva, S.A.; Riva, R.; Vasconcelos, G. [Instituto de Estudos Avancados (IEAv), Sao Jose dos Campos, SP (Brazil); Silva Pita, G.R. [Universidade Braz Cubas, Mogi das Cruzes, SP (Brazil); Yamin, L.S. [Escola Tecnica Everardo Passos (ETEP), Sao Jose dos Campos, DP (Brazil)

    2016-07-01

    Full text: Zirconium-based ceramic materials are widely employed as Thermal Barrier Coatings (TBC), due to its excellent wear and corrosion resistance at high temperatures. The application of TBC includes aeronautical and industrials turbine blades. The working conditions include oxidizing environments and temperatures above 1000°C. The zirconium-based ceramics are developed in such a way that the microstructural control is possible through the control of chemical composition, fabrication route and, thermal treatment. The present paper proposes a laser route to deposit the TBC coating, where the microstructural control is a function of power density and interaction time between the laser beam and the material. The main objective of this work is to study the influence of the CO2 laser beam (Synrad Evolution 125) parameters: power density and interaction time, on the deposition process of yttria-stabilized zirconia (YSZ) powders on NiCrAlY/AISI 316L substrates. The resulting coating surface and interface were characterized by scanning electron microscopy, energy dispersive spectroscopy and X-ray diffraction. The results indicate that is possible to match laser parameters of scanning speed and intensity to produce homogenous coatings. The X-Ray analyses show that the obtained ceramic coating has reduced number of phases, with prevalence of tetragonal phase.(author)

  2. MOX fuel fabrication at AECL

    International Nuclear Information System (INIS)

    Dimayuga, F.C.; Jeffs, A.T.

    1995-01-01

    Atomic Energy of Canada Limited's mixed-oxide (MOX) fuel fabrication activities are conducted in the Recycle Fuel Fabrication Laboratories (RFFL) at the Chalk River Laboratories. The RFFL facility is designed to produce experimental quantities of CANDU MOX fuel for reactor physics tests or demonstration irradiations. From 1979 to 1987, several MOX fuel fabrication campaigns were run in the RFFL, producing various quantities of fuel with different compositions. About 150 bundles, containing over three tonnes of MOX, were fabricated in the RFFL before operations in the facility were suspended. In late 1987, the RFFL was placed in a state of active standby, a condition where no fuel fabrication activities are conducted, but the monitoring and ventilation systems in the facility are maintained. Currently, a project to rehabilitate the RFFL and resume MOX fuel fabrication is nearing completion. This project is funded by the CANDU Owners' Group (COG). The initial fabrication campaign will consist of the production of thirty-eight 37-element (U,Pu)O 2 bundles containing 0.2 wt% Pu in Heavy Element (H.E.) destined for physics tests in the zero-power ZED-2 reactor. An overview of the Rehabilitation Project will be given. (author)

  3. Design and fabrication of the superconducting-magnet system for the Mirror Fusion Test Facility (MFTF-B)

    International Nuclear Information System (INIS)

    Tatro, R.E.; Wohlwend, J.W.; Kozman, T.A.

    1982-01-01

    The superconducting magnet system for the Mirror Fusion Test Facility (MFTF-B) consists of 24 magnets; i.e. two pairs of C-shaped Yin-Yang coils, four C-shaped transition coils, four solenoidal axicell coils, and a 12-solenoid central cell. General Dynamics Convair Division has designed all the coils and is responsible for fabricating 20 coils. The two Yin-Yang pairs (four coils) are being fabricated by the Lawrence Livermore National Laboratory. Since MFTF-B is not a magnet development program, but rather a major physics experiment critical to the mirror fusion program, the basic philosophy has been to use proven materials and analytical techniques wherever possible. The transition and axicell coils are currently being analyzed and designed, while fabrication is under way on the solenoid magnets

  4. Systems and methods for large-scale nanotemplate and nanowire fabrication

    KAUST Repository

    Vidal, Enrique Vilanova

    2016-03-31

    Systems and methods for largescale nanotemplate and nanowire fabrication are provided. The system can include a sample holder and one or more chemical containers fluidly connected to the sample holder. The sample holder can be configured to contain a solution and to releasably hold a substrate material within the solution. In other aspects, the system can include a robotic arm including a head configured to releasably hold a substrate material. The methods can include initiating a treatment step by moving a chemical solution from a chemical container to the sample holder to submerge the substrate material for a period of time. The methods can include moving the robotic arm to position the substrate in a chemical container. The treatment steps can be stopped by removing the chemical solution from the sample holder or by moving the robotic arm to remove the substrate from the chemical container. The treatment steps can include degreasing, polishing, rinsing, anodization, and deposition.

  5. From Nano Structure to Systems: Fabrication and Characterization

    International Nuclear Information System (INIS)

    Uda Hashim

    2011-01-01

    Currently, the interest in nano technology research has been grown rapidly. With the latest technology, it is possible to arrange atoms into structures that are only a few nanometers in size. Dimension for nano structure is between 0.1 and 100nm where the actual size of 1nm is equal to 10-9 m or just about a few atoms thick. In other word, a nano structure is an object which it size is about four atom diameters or 1/50000 of a human hair. Due to the connecting of a patterned silicon substrate with biomolecules and the small size and large surface-to-volume ratio, it opens much new possibility for assembling nano structures.The ultimate goal is to fabricate devices that have every atom in the right place. Such technology would give the opportunity to minimize the size of a device and to reduce the material, energy and time necessary to perform its task. Potential applications include electrical circuits, mechanical devices and medical instruments. There are two most important nano structures that are extensively studied and researched in various organizations which are nano wire and nano gap. Nano wires is a new class of nano structure that have attracted attention and great research interest in the last few years because of their potential applications in nano technology such as nano electronic, nano mechanical and biomedical engineering. Fabrication of Nano wires is one of the great challenges today. Conventional lithography methods are not capable to produce Nano wires and even with advance nano lithography sizes below 100 nm may not easily be achieved. Nano wire can be produced in two approaches, which are top down and bottom-up method. Very small nano wires which can be produced by using top-down nano fabrication methods are Scanning Electron Microscope (SEM) based Electron Beam Lithography (EBL) method, and Spacer Patterning Lithography (SPL) method. The top-down nano fabrication method based on EBL was the design of the Nano wires Pattern Design (NPD). The

  6. EIT-based fabric pressure sensing.

    Science.gov (United States)

    Yao, A; Yang, C L; Seo, J K; Soleimani, M

    2013-01-01

    This paper presents EIT-based fabric sensors that aim to provide a pressure mapping using the current carrying and voltage sensing electrodes attached to the boundary of the fabric patch. Pressure-induced shape change over the sensor area makes a change in the conductivity distribution which can be conveyed to the change of boundary current-voltage data. This boundary data is obtained through electrode measurements in EIT system. The corresponding inverse problem is to reconstruct the pressure and deformation map from the relationship between the applied current and the measured voltage on the fabric boundary. Taking advantage of EIT in providing dynamical images of conductivity changes due to pressure induced shape change, the pressure map can be estimated. In this paper, the EIT-based fabric sensor was presented for circular and rectangular sensor geometry. A stretch sensitive fabric was used in circular sensor with 16 electrodes and a pressure sensitive fabric was used in a rectangular sensor with 32 electrodes. A preliminary human test was carried out with the rectangular sensor for foot pressure mapping showing promising results.

  7. EIT-Based Fabric Pressure Sensing

    Directory of Open Access Journals (Sweden)

    A. Yao

    2013-01-01

    Full Text Available This paper presents EIT-based fabric sensors that aim to provide a pressure mapping using the current carrying and voltage sensing electrodes attached to the boundary of the fabric patch. Pressure-induced shape change over the sensor area makes a change in the conductivity distribution which can be conveyed to the change of boundary current-voltage data. This boundary data is obtained through electrode measurements in EIT system. The corresponding inverse problem is to reconstruct the pressure and deformation map from the relationship between the applied current and the measured voltage on the fabric boundary. Taking advantage of EIT in providing dynamical images of conductivity changes due to pressure induced shape change, the pressure map can be estimated. In this paper, the EIT-based fabric sensor was presented for circular and rectangular sensor geometry. A stretch sensitive fabric was used in circular sensor with 16 electrodes and a pressure sensitive fabric was used in a rectangular sensor with 32 electrodes. A preliminary human test was carried out with the rectangular sensor for foot pressure mapping showing promising results.

  8. High temperature oxidation behavior of hafnium modified NiAl bond coat in EB-PVD thermal barrier coating system

    Energy Technology Data Exchange (ETDEWEB)

    Guo Hongbo; Sun Lidong; Li Hefei [Department of Material Science and Engineering, Beijing University of Aeronautics and Astronautics, No.37 Xueyuan Road, Beijing 100083 (China); Gong Shengkai [Department of Material Science and Engineering, Beijing University of Aeronautics and Astronautics, No.37 Xueyuan Road, Beijing 100083 (China)], E-mail: gongsk@buaa.edu.cn

    2008-06-30

    NiAl coatings doped with 0.5 at.% and 1.5 at.% Hf were produced by co-evaporation of NiAl and Hf ingots by electron beam physical vapor deposition (EB-PVD), respectively. The addition of 0.5 at.% Hf significantly improved the cyclic oxidation resistance of the NiAl coating. The TGO layer in the 1.5 at.% Hf doped NiAl coating is straight; while that in the 0.5 at.% Hf doped coating became undulated after thermal cycling. The doped NiAl thermal barrier coatings (TBCs) revealed improved thermal cycling lifetimes at 1423 K, compared to the undoped TBC. Failure of the 0.5 at.% Hf doped TBC occurred by cracking at the interface between YSZ topcoat and bond coat, while the 1.5 at.% Hf doped TBC cracked at the interface between bond coat and substrate.

  9. On the interfacial degradation mechanisms of thermal barrier coating systems: Effects of bond coat composition

    Energy Technology Data Exchange (ETDEWEB)

    Wu, R.T., E-mail: WU.Rudder@nims.go.jp [International Center for Young Scientists, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba City, Ibaraki (Japan); Wang, X.; Atkinson, A. [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2BP (United Kingdom)

    2010-10-15

    Thermal barrier coating (TBC) systems based on an electron beam physical vapour deposited, yttria-stabilized zirconia (YSZ) top coat and a substrate material of CMSX-4 superalloy were identically prepared to systematically study the behaviour of different bond coats. The three bond coat systems investigated included two {beta}-structured Pt-Al types and a {gamma}-{gamma}' type produced by Pt diffusion without aluminizing. Progressive evolution of stress in the thermally grown aluminium oxide (TGO) upon thermal cycling, and its relief by plastic deformation and fracture, were studied using luminescence spectroscopy. The TBCs with the LT Pt-Al bond coat failed by a rumpling mechanism that generated isolated cracks at the interface between the TGO and the YSZ. This reduced adhesion at this interface and the TBC delaminated when it could no longer resist the release of the stored elastic energy of the YSZ, which stiffened with time due to sintering. In contrast, the TBCs with Pt diffusion bond coats did not rumple, and the adhesion of interfaces in the coating did not obviously degrade. It is shown that the different failure mechanisms are strongly associated with differences in the high-temperature mechanical properties of the bond coats.

  10. Automatic measurement for dimensional changes of woven fabrics based on texture

    Science.gov (United States)

    Liu, Jihong; Jiang, Hongxia; Liu, X.; Chai, Zhilei

    2014-01-01

    Dimensional change or shrinkage is an important functional attribute of woven fabrics that affects their basic function and price in the market. This paper presents a machine vision system that evaluates the shrinkage of woven fabrics by analyzing the change of fabric construction. The proposed measurement method has three features. (i) There will be no stain of shrinkage markers on the fabric specimen compared to the existing measurement method. (ii) The system can be used on fabric with reduced area. (iii) The system can be installed and used as a laboratory or industrial application system. The method processed can process the image of the fabric and is divided into four steps: acquiring a relative image from the sample of the woven fabric, obtaining a gray image and then the segmentation of the warp and weft from the fabric based on fast Fourier transform and inverse fast Fourier transform, calculation of the distance of the warp or weft sets by gray projection method and character shrinkage of the woven fabric by the average distance, coefficient of variation of distance and so on. Experimental results on virtual and physical woven fabrics indicated that the method provided could obtain the shrinkage information of woven fabric in detail. The method was programmed by Matlab software, and a graphical user interface was built by Delphi. The program has potential for practical use in the textile industry.

  11. Bone induction by surface-double-modified true bone ceramics in vitro and in vivo

    International Nuclear Information System (INIS)

    Li, Jingfeng; Chen, Liaobin; Deng, Yu; Zheng, Qixin; Guo, Xiaodong; Zou, Zhenwei; Liu, Yudong; Lan, Shenghui

    2013-01-01

    True bone ceramic (TBC), obtained by twice sintering fresh bovine cancellous bone at high temperatures, is an osteoconductive and bioactive bone substitute material that exhibits excellent biocompatibility with hard tissue. The authors have previously synthesized a novel BMP-2-related peptide, P24, and found that it could enhance the osteoblastic differentiation of cells. The objective of the present study was to construct a double-modified TBC via mineralization into simulated body fluid and P24 incorporation for enhanced bone formation. In vitro experiments revealed that surface mineralization-modified (SMM) TBC scaffolds demonstrated efficiency for sustained release of P24. The P24/SMM-TBC composite exhibited increased osteogenic activity by cell adhesion rate determination, MTT assay, alkaline phosphatase staining, and calcium nodule staining with alizarin red compared with SMM-TBC and TBC. In vivo studies showed that the P24/SMM-TBC composite scaffold promoted significant bone defect repair, in marked contrast to stand-alone SMM-TBC and TBC, based on the results of radiographic evaluation and histological examination. These findings indicate that SMM-TBC is a good scaffold for the controlled release of P24 and that the P24/SMM-TBC composite could improve the adhesion, proliferation and differentiation of cells and repair bone defects. The double-modified P24/SMM-TBC composite biomaterial shows potential for clinical application in bone tissue engineering. (paper)

  12. Herd characteristics and management practices associated with bulk tank milk quality of dairy herds in southeastern Brazil.

    Science.gov (United States)

    Cortinhas, Cristina Simões; Botaro, Bruno Garcia; de Macedo, Susana Nori; Dos Santos, Marcos Veiga

    2018-04-30

    This study identified the association of management practices and herd characteristics with milk quality of bulk tanks in southeastern, Brazil. Milk samples were collected weekly during 8 weeks from 63 dairy herds. Bulk tanks were evaluated for total bacteria (TBC), preliminary incubation (PIC), pasteurization (PC), coliform (CC), and somatic cell counts (SCC). Associations found were type of milking system utilized in the farm with TBC, PIC, and SCC; the use of gloves for milking with TBC and PIC; sanitation of milking equipment prior to milking with PC and CC; strip cup testing of cows with PC; teat washing prior to milking with SCC; pre-milking teat disinfection with TBC and CC; post-dipping with TBC and SCC; and the alkaline-acid washing procedure of milking equipment with PIC and PC. The regression analysis explained the variation of bulk tank PC (- 0.47 log cfu/mL) due to the adoption of strip cup test (P = 0.036) and, by 0.366 log cfu/mL due to alkaline and acid washing of milking equipment (P = 0.036). Herringbone milking systems adopted on farms represented a change of - 0.11 log cfu/mL on the log SCC (P = 0.048). Findings may provide a guideline to prioritize efforts aimed at improving milk quality at the farm level in Brazil.

  13. Steel-fabricated butterfly valves for condenser circulating water system

    International Nuclear Information System (INIS)

    Kawase, Hiroshi; Yasuoka, Masahiro; Nanao, Teruaki.

    1979-01-01

    The steel-fabricated butterfly valves, which are large in general, and gave rubber linings inside to prevent the corrosion due to sea Water, are utilized for the condenser circulating water systems of thermal and nuclear power plants. Cast iron butterfly valves, having been used hitherto, have some technical irrationalities, such as corrosion prevention, the techniques for manufacturing large castings, severe thermal transient operation. On the contrary, the steel plate-fabricated butterfly valves have the following advantages; much superior characteristics in strength, rigidity and shock resistance, the streamline shape of valve plates, the narrow width between two flanges, superior execution of works for rubber lining, the perfect sealed structure, safety to vibration, light weight and easy maintenance. The structural design and the main specifications for the steel plate butterfly valves with the nominal bore from 1350 mm to 3500 mm are presented. Concerning the design criteria, the torque of operating butterfly valves and the strength of valve bodies, valve plates and valve stems are explained. The performance tests utilizing the mock-up valve were carried out for the measurements of stress distribution, the deformation of valve body, the endurance and the operating torque. In the welding standards for steel plate butterfly valves, three kinds of welded parts are classified, and the inspection method for each part is stipulated. The vibration of the valves induced by flow vortexes and cavitation is explained. (Nakai, Y.)

  14. Fabrics for fire resistant passenger seats in aircraft

    Science.gov (United States)

    Tesoro, G. C.

    1978-01-01

    The essential elements of the problem and of approaches to improved fire resistance in aircraft seats are reviewed. The performance requirements and availability of materials, delay in the ignition of upholstery fabric by a small source are considered a realistic objective. Results of experimental studies on the thermal response of fabrics and fabric/foam combinations suggest significant conclusions regarding: (1) the ignition behavior of a commercial 90/10 wool/nylon upholstery fabric relative to fabrics made from thermally stable polymers; (2) the role of the foam backing; (3) the behavior of seams. These results, coupled with data from other sources, also confirm the importance of materials' interactions in multicomponent assemblies, and the need for system testing prior to materials' selection. The use of an interlinear or thermal barrier between upholstery fabric and foam is a promising and viable approach to improved fire resistance of the seat assembly, but experimental evaluation of specific combinations of materials or systems is an essential part of the selection process.

  15. Shear strength of a thermal barrier coating parallel to the bond coat

    International Nuclear Information System (INIS)

    Cruse, T.A.; Dommarco, R.C.; Bastias, P.C.

    1998-01-01

    The static and low cycle fatigue strength of an air plasma sprayed (APS) partially stabilized zirconia thermal barrier coating (TBC) is experimentally evaluated. The shear testing utilized the Iosipescu shear test arrangement. Testing was performed parallel to the TBC-substrate interface. The TBC testing required an innovative use of steel extensions with the TBC bonded between the steel extensions to form the standard Iosipescu specimen shape. The test method appears to have been successful. Fracture of the TBC was initiated in shear, although unconstrained specimen fractures propagated at the TBC-bond coat interface. The use of side grooves on the TBC was successful in keeping the failure in the gage section and did not appear to affect the shear strength values that were measured. Low cycle fatigue failures were obtained at high stress levels approaching the ultimate strength of the TBC. The static and fatigue strengths do not appear to be markedly different from tensile properties for comparable TBC material

  16. Carbon material based microelectromechanical system (MEMS): Fabrication and devices

    Science.gov (United States)

    Xu, Wenjun

    silicon and metal based microsystems. In this thesis, this mature technique was exploited to generate a variety of microelectrode structures to facilitate the micropatterning and manipulation of the CNTs. Selective deposition of electrically charged CNTs onto desired locations was realized in an EPD process through patterning of electric field lines created by the microelectrodes fabricated through MEMS techniques. A variety of 2-D and 3-D micropatterns of CNTs with waferscale areas have been successfully achieved in both rigid and elastic systems. The thickness and morphology of the generated CNT patterns was found to be readily controllable through the parameters of the fabrication process. Studies also showed that for this technique, high surface hydrophobicity of the non-conductive regions in microstructures was critical to accomplish well-defined selective micropatterning of CNTs. Upon clearing the hurdles of the CNT manipulation, a patterned PDMS/CNT nanocomposite was fabricated through the aforementioned approach and was incorporated, investigated and validated in elastic force/strain microsensors. The gauge factor of the sensor exhibited a strong dependence on both the initial resistance of the device and the applied strain. Detailed analysis of the data suggests that the piezoresistive effect of this specially constructed bi-layer composite could be due to three mechanisms, and the sensing mechanism may vary when physical properties of the CNT network embedded in the polymer matrix alter. The feasibility of the PDSM/CNT composite being utilized as an elastic electret was further explored. The nanocomposite composed of these two non-traditional electret materials exhibited electret characteristics with reasonable charge storage stability when charged using a corona discharge. The power generation capacity of the corona-charged composite has been characterized and successfully demonstrated in both a ball drop experiment and cyclic mechanical load experiments

  17. Development of technology for fabrication of lithium CPS on basis of CNT-reinforced carboxylic fabric

    Energy Technology Data Exchange (ETDEWEB)

    Tazhibayeva, Irina, E-mail: tazhibayeva@ntsc.kz [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Baklanov, Viktor; Ponkratov, Yuriy [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Abdullin, Khabibulla [Institute of Experimental and Theoretical Physics of Kazakh National University, Almaty (Kazakhstan); Kulsartov, Timur; Gordienko, Yuriy; Zaurbekova, Zhanna [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Lyublinski, Igor [JSC «Red Star», Moscow (Russian Federation); NRNU «MEPhI», Moscow (Russian Federation); Vertkov, Alexey [JSC «Red Star», Moscow (Russian Federation); Skakov, Mazhyn [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan)

    2017-04-15

    Highlights: • Preliminary study of carboxylic fabric wettability with liquid lithium is presented. • Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673,773 and 873 К in vacuum during long time. • A scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. • The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed. - Abstract: The paper describes the analysis of liquid lithium interaction with materials based on carbon, the manufacture technology of capillary-porous system (CPS) matrix on basis of CNT-reinforced carboxylic fabric. Preliminary study of carboxylic fabric wettability with liquid lithium is presented. The development of technology includes: microstructural studies of carboxylic fabric before its CNT-reinforcing; validation of CNT-reinforcing technology; mode validation of CVD-method for CNT synthesize; study of synthesized carbon structures. Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673, 773 and 873 К in vacuum during long time. The scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed.

  18. Development of technology for fabrication of lithium CPS on basis of CNT-reinforced carboxylic fabric

    International Nuclear Information System (INIS)

    Tazhibayeva, Irina; Baklanov, Viktor; Ponkratov, Yuriy; Abdullin, Khabibulla; Kulsartov, Timur; Gordienko, Yuriy; Zaurbekova, Zhanna; Lyublinski, Igor; Vertkov, Alexey; Skakov, Mazhyn

    2017-01-01

    Highlights: • Preliminary study of carboxylic fabric wettability with liquid lithium is presented. • Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673,773 and 873 К in vacuum during long time. • A scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. • The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed. - Abstract: The paper describes the analysis of liquid lithium interaction with materials based on carbon, the manufacture technology of capillary-porous system (CPS) matrix on basis of CNT-reinforced carboxylic fabric. Preliminary study of carboxylic fabric wettability with liquid lithium is presented. The development of technology includes: microstructural studies of carboxylic fabric before its CNT-reinforcing; validation of CNT-reinforcing technology; mode validation of CVD-method for CNT synthesize; study of synthesized carbon structures. Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673, 773 and 873 К in vacuum during long time. The scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed.

  19. Thermal insulation system design and fabrication specification (nuclear) for the Clinch River Breeder Reactor plant

    International Nuclear Information System (INIS)

    1978-01-01

    This specification defines the design, analysis, fabrication, testing, shipping, and quality requirements of the Insulation System for the Clinch River Breeder Reactor Plant (CRBRP), near Oak Ridge, Tennessee. The Insulation System includes all supports, convection barriers, jacketing, insulation, penetrations, fasteners, or other insulation support material or devices required to insulate the piping and equipment cryogenic and other special applications excluded. Site storage, handling and installation of the Insulation System are under the cognizance of the Purchaser

  20. A biomimic thermal fabric with high moisture permeability

    Directory of Open Access Journals (Sweden)

    Fan Jie

    2013-01-01

    Full Text Available Moisture comfort is an essential factor for functional property of thermal cloth, especially for thick thermal cloth, since thick cloth may hinder effective moisture permeation, and high moisture concentration in the micro-climate between skin and fabric would cause cold feeling. Here, we report a biomimic thermal fabric with excellent warm retention and moisture management properties. In this fabric, the warp yarn system constructs many tree-shaped channel nets in the thickness direction of the fabric. Experimental result indicates that the special hierarchic configuration of warp yarns endows the biomimic thermal fabric with a better warm retention and water vapor management properties compared with the traditional fabrics.

  1. Composition-graded nanowire solar cells fabricated in a single process for spectrum-splitting photovoltaic systems.

    Science.gov (United States)

    Caselli, Derek; Liu, Zhicheng; Shelhammer, David; Ning, Cun-Zheng

    2014-10-08

    Nanomaterials such as semiconductor nanowires have unique features that could enable novel optoelectronic applications such as novel solar cells. This paper aims to demonstrate one such recently proposed concept: Monolithically Integrated Laterally Arrayed Multiple Band gap (MILAMB) solar cells for spectrum-splitting photovoltaic systems. Two cells with different band gaps were fabricated simultaneously in the same process on a single substrate using spatially composition-graded CdSSe alloy nanowires grown by the Dual-Gradient Method in a chemical vapor deposition system. CdSSe nanowire ensemble devices tested under 1 sun AM1.5G illumination achieved open-circuit voltages up to 307 and 173 mV and short-circuit current densities as high as 0.091 and 0.974 mA/cm(2) for the CdS- and CdSe-rich cells, respectively. The open-circuit voltages were roughly three times those of similar CdSSe film cells fabricated for comparison due to the superior optical quality of the nanowires. I-V measurements were also performed using optical filters to simulate spectrum-splitting. The open-circuit voltages and fill factors of the CdS-rich subcells were uniformly larger than the corresponding CdSe-rich cells for similar photon flux, as expected. This suggests that if all wires can be contacted, the wide-gap cell is expected to have greater output power than the narrow-gap cell, which is the key to achieving high efficiencies with spectrum-splitting. This paper thus provides the first proof-of-concept demonstration of simultaneous fabrication of MILAMB solar cells. This approach to solar cell fabrication using single-crystal nanowires for spectrum-splitting photovoltaics could provide a future low-cost high-efficiency alternative to the conventional high-cost high-efficiency tandem cells.

  2. Repair of rabbit radial bone defects using true bone ceramics combined with BMP-2-related peptide and type I collagen

    International Nuclear Information System (INIS)

    Li Jingfeng; Lin Zhenyu; Zheng Qixin; Guo Xiaodong; Lan Shenghui; Liu Sunan; Yang Shuhua

    2010-01-01

    An ideal bone graft material is the one characterized with good biocompatibility, biodegradation, osteoconductivity and osteoinductivity. In this study, a novel synthetic BMP-2-related peptide (designated P24) corresponding to residues of the knuckle epitope of BMP-2 was introduced into a biomimetic scaffold based on sintered bovine bone or true bone ceramics (TBC) and type I collagen (TBC/collagen I) using a simulated body fluid (SBF). Hydroxylapatite crystal mineralization with a Ca/P molar ratio of 1.63 was observed on the surface of P24/TBC/collagen I composite by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) techniques. Cell adhesion rate evaluation of bone marrow stromal cells (BMSCs) seeded on materials in vitro showed that the percentage of cells attached to P24/TBC/collagen I composite was significantly higher than that of the TBC/collagen I composite. A 10 mm unilateral segmental bone defect was created in the radius of New Zealand white rabbits and randomly implanted with three groups of biomaterials (Group A: P24/TBC/collagen I composite; Group B: TBC/collagen I composite and Group C: TBC alone). Based on radiographic evaluation and histological examination, the implants of P24/TBC/collagen I composite significantly stimulated bone growth, thereby confirming the enhanced rate of bone healing compared with that of TBC/collagen I composite and TBC alone. It was concluded that BMP-2-related peptide P24 could induce nucleation of calcium phosphate crystals on the surface of TBC/collagen I composite. The TBC/collagen I composite loaded with the synthetic BMP-2-related peptide is a promising scaffold biomaterial for bone tissue engineering.

  3. Prevention of significant deterioration permit application for the Fueled Clad Fabrication System, the Radioisotope Power Systems Facility, and the Fuel Assembly Area

    Energy Technology Data Exchange (ETDEWEB)

    1989-08-01

    This New Source Review'' has been submitted by the US Department of Energy-Richland Operations Office (PO Box 550, Richland, Washington 99352), pursuant to WAC 173-403-050 and in compliance with the Department of Ecology Guide to Processing A Prevention Of Significant Deterioration (PSD) Permit'' for three new sources of radionuclide emissions at the Hanford Site in Washington State. The three new sources, the Fueled Clad Fabrication System (FCFS), the Radioisotope Power Systems Facility (RPSF), and the Fuel Assembly Area (FAA), will be located in one facility, the Fuels and Materials Examination Facility (FMEF) of the 400 Area. The FMEF was originally designed to provide for post-irradiation examination and fabrication of breeder reactor fuels. These FMEF missions were cancelled before the introduction of any fuel materials or any irradiated material. The current plans are to use the facility to fabricate power supplies for use in space applications and to produce Fast Flux Test Facility (FFTF) fuel and target assemblies. The FCFS and the RPSF will produce materials and assemblies for application in space. The FAA project will produce FFTF fuel and target assemblies. The FCFS and the RPSF will share the same building, stack, and, in certain cases, the same floor space. Given this relationship, these systems will be dealt with separately to the extent possible. The FAA is a comparatively independent operation though it will share the FMEF complex.

  4. Supplemental information for a notice of construction for the Fueled Clad Fabrication System, the Radioisotope Power Systems Facility, and the Fuel Assembly Area

    Energy Technology Data Exchange (ETDEWEB)

    1989-08-01

    This ''Notice of Construction'' has been submitted by the US Department of Energy-Richland Operations Office (P.O. Box 550, Richland, Washington 99352), pursuant to WAC 402-80-070, for three new sources of radionuclide emissions at the Hanford Site in Washington State (Figure 1). The three new sources, the Fueled Clad Fabrication System (FCFS) the Radioisotope Power Systems Facility (RPSF) and the Fuel Assembly Area (FAA) will be located in one facility, the Fuels and materials Examination Facility (FMEF) of the 400 Area. The FMEF was originally designed to provide for post- irradiation examination and fabrication of breeder reactor fuels. These FMEF missions were cancelled before the introduction of any fuel materials or any irradiated material. The current plans are to use the facility to fabricate power supplies to be used in space applications and to produce Fast Flux Test Facility (FFTF) fuel and target assemblies. The FCFS and the RPSF will produce materials and assemblies for application in space. The FAA project will produce FFTF fuel and target assemblies. The FCFS and the RPSF will share the same building, stack, and, in certain cases, the same floor space. Given this relationship, to the extent possible, these systems will be dealt with separately. The FAA is a comparatively independent operation though it will share the FMEF complex.

  5. Construction, fabrication, and installation

    International Nuclear Information System (INIS)

    1992-05-01

    This standard specifies the construction, fabrication, and installation requirements that apply to concrete containment structures of a containment system designated as class containment components, parts and appurtenances for nuclear power plants

  6. Fabrication of remote steam atomized scrubbers for DWPF off-gas system

    International Nuclear Information System (INIS)

    Nielsen, M.G.; Lafferty, J.D.

    1988-01-01

    The defense waste processing facility (DWPF) is being constructed for the purpose of processing high-level waste from sludge to a vitrified borosilicate glass. In the operation of continuous slurry-fed melters, off-gas aerosols are created by entrainment of feed slurries and the vaporization of volatile species from the molten glass mixture. It is necessary to decontaminate these aerosols in order to minimize discharge of airborne radionuclide particulates. A steam atomized scrubber (SAS) has been developed for DWPF which utilizes a patented hydro- sonic system gas scrubbing method. The Hydro-Sonic System utilizes a steam aspirating-type venturi scrubber that requires very precise fabrication tolerances in order to obtain acceptable decontamination factors. In addition to the process-related tolerances, precision mounting and nozzle tolerances are required for remote service at DWPF

  7. Process Modelling of Rapid Manufacturing Based Mass Customisation System for Fabrication of Custom Foot Orthoses: Review Paper

    Directory of Open Access Journals (Sweden)

    Saleh Jumani

    2013-04-01

    Full Text Available The need for custom-made devices, rehabilitation aids and treatments is explicit in the medical sector. Applications of rapid manufacturing techniques based on additive fabrication processes combined with medical digitising technologies can generate high quality solutions in situations where the need for custom-made devices and rehabilitation aids and low-lead times are very important factors. Foot orthoses are medical devices applied in the treatment of biomechanical foot disorders, foot injuries and foot diseases including rheumatoid arthritis and diabetes. The significant challenge in the treatment of foot related diseases is progressing pathological deterioration in the affected sites of the foot which requires quick provision of the orthoses. A process model is developed using the IDEF0 modelling technique in which a rapid manufacturing approach is integrated in the design and fabrication process of custom foot orthoses. The process model will be used in the development of rapid manufacturing based design and fabrication system for mass customisation of foot orthoses. The developed system is aimed at mass scale production of custom foot orthoses with the advantages of reduced cost, reduced lead-time and improved product in terms of increased fit, consistency and accuracy in the final product.

  8. Season influence on milk physico-chemical and microbiological aspects in Western Santa Catarina

    Directory of Open Access Journals (Sweden)

    Flávio José Simioni

    2014-09-01

    Full Text Available The objective of this study was to analyze the influence of seasonal changes on milk quality in Western Santa Catarina, Brazil. Dairy farms (799 had raw milk samples (9144 collected and analyzed for fat, protein, SCC (somatic cell count and TBC (total bacterial count. Samples were collected from cooling tanks on the farm during the months of October 2009 to September 2010 and grouped into four seasons (summer, autumn, winter, and spring. The data were classified according to the normative instructions 51 and 62 the Ministerial of Agriculture, and also according to a quality pay system adopted by the dairy industry in the region of the study. The results revealed differences between groups (P<0.05, where fat content was higher in autumn, protein and TBC were higher in winter and SCC showed the highest rates in the summer. According to the criteria established by legislation, the main quality problem was the TBC, with higher counts in the winter, and in the summer we observed the highest percentage of non-compliant samples. For the quality payment system, chemical composition resulted on better prices to be paid to producers, while TBC was primarily responsible lower price.

  9. Feasibility Study of Laser Cutting for Fabrication of Tensile Specimen

    International Nuclear Information System (INIS)

    Jin, Y. G.; Baik, S. J.; Kim, G. S.; Heo, G. S.; Yoo, B. O.; Ahn, S. B.; Chun, Y. B.

    2015-01-01

    The specimen fabrication technique was established to machine the specimen from the irradiated materials. The wire cut EDM(electric discharge machine) was modified to fabricate the mechanical testing specimens from irradiated components and fuel claddings. The oxide layer removal system was also developed because the oxide layer on the surface of the irradiated components and claddings interrupted the applying the electric current during the processing. However, zirconium oxide is protective against further corrosion as well as beneficial to mechanical strength for the tensile deformation of the cladding. Thus, it is important to fabricate the irradiated specimens without removal of oxide layer on the surface of the irradiated structural components and claddings. In the present study, laser cutting system was introduced to fabricate the various mechanical testing specimens from the unirradiated fuel cladding and the feasibility of the laser cutting system was studied for the fabrication of various types of irradiated specimens in a hot cell at IMEF (Irradiated Materials Examination Facility) of KAERI. Laser beam machining system was introduced to fabricate the various mechanical testing specimens from the unirradiated fuel cladding and the dimensions were compared for the feasibility of the laser cutting system. The effect of surface oxide layer was also investigated for machining process of the zircaloy-4 fuel cladding and it was found that laser beam machining could be a useful tool to fabricate the specimens with surface oxide layer

  10. Feasibility Study of Laser Cutting for Fabrication of Tensile Specimen

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Y. G.; Baik, S. J.; Kim, G. S.; Heo, G. S.; Yoo, B. O.; Ahn, S. B.; Chun, Y. B. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    The specimen fabrication technique was established to machine the specimen from the irradiated materials. The wire cut EDM(electric discharge machine) was modified to fabricate the mechanical testing specimens from irradiated components and fuel claddings. The oxide layer removal system was also developed because the oxide layer on the surface of the irradiated components and claddings interrupted the applying the electric current during the processing. However, zirconium oxide is protective against further corrosion as well as beneficial to mechanical strength for the tensile deformation of the cladding. Thus, it is important to fabricate the irradiated specimens without removal of oxide layer on the surface of the irradiated structural components and claddings. In the present study, laser cutting system was introduced to fabricate the various mechanical testing specimens from the unirradiated fuel cladding and the feasibility of the laser cutting system was studied for the fabrication of various types of irradiated specimens in a hot cell at IMEF (Irradiated Materials Examination Facility) of KAERI. Laser beam machining system was introduced to fabricate the various mechanical testing specimens from the unirradiated fuel cladding and the dimensions were compared for the feasibility of the laser cutting system. The effect of surface oxide layer was also investigated for machining process of the zircaloy-4 fuel cladding and it was found that laser beam machining could be a useful tool to fabricate the specimens with surface oxide layer.

  11. Remote fabrication of breeder reactor fuel

    International Nuclear Information System (INIS)

    Gerber, E.W.; Hoitink, N.C.; Graham, R.A.

    1984-06-01

    The Secure Automated Fabrication (SAF) Line, a remotely operable plutonium fuel fabrication facility, incorporates advanced automation techniques. Included in the plant are 24 robots used to perform complex operations, and to enhance equipment standardization and ease of maintenance. Automated equipment is controlled remotely from centrally located supervisory computer control consoles or alternatively from control consoles dedicated to individual systems

  12. Morbi-mortalidad de pacientes con tuberculosis hospitalizados en el Departamento de enfermedades infecciosas, tropicales y dermatológicas del Hospital Nacional Cayetano Heredia, Lima - Perú entre los años 1990 y 2000

    Directory of Open Access Journals (Sweden)

    Raul Chuquiyauri Haro

    2004-10-01

    Full Text Available Objetivos: Describir las características clínico-epidemiológicas y la mortalidad de pacientes hospitalizados con tuberculosis (TBC en el Departamento de Enfermedades Infecciosas, Tropicales y Dermatológicas del Hospital Nacional Cayetano Heredia (DEITD-HNCH de Lima, Perú. Material y Métodos: Estudio retrospectivo y observacional que incluyó a pacientes hospitalizados desde enero de 1990 hasta diciembre de 2000 con diagnóstico de TBC definitiva o probable. Resultados: Se registraron 1340 altas con diagnóstico de TBC (18.7 %. La edad promedio de los pacientes hospitalizados con TBC fue 33.5 ± 15.1 años, 69.2% fueron varones y 28.1 % tuvieron infección por el Virus de la Inmunodeficiencia Humana (VIH. La mortalidad por TBC fue 17.2 % y permaneció constante durante el período. El número de muertes por TBC (230 pacientes representó el 37.5 % de las muertes por todas las causas (613 pacientes. De los fallecidos por TBC, 151 (65.6 % tuvieron TBC multisistémica, 60 (26.1 % TBC pulmonar y 19 (8.3 % TBC extrapulmonar exclusiva. Hubo sospecha clínica de TBC multidrogorresistente (TBC-MDR en 51 (22.2 % pacientes fallecidos. Edad mayor de 30 años (OR=1.6, 1.2TBC. Conclusiones: Tuberculosis representó el 18.7% del total de diagnósticos y el 37.5% de las muertes por todas las causas. La mortalidad relacionada con TBC en la unidad de enfermedades infecciosas de un hospital público referencial no ha disminuido en los últimos 11 años. Infección por VIH y ser mayor de 30 años están asociados a mortalidad. (Rev Med Hered 2004; 15:203-210.

  13. Integrated Fabrication of a Microgripper

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Successful implementation of simple mechanism on silicon chip is a prerequisite for monolithic microrobot-ic systems. This paper describes the integrated fabrication of polycrystalline silicon microgripper. Link, fixed andactive joint, and sliding flange structures with dimensions of micrometers have been fabricated on the substrate ofmonocrystalline silicon using silicon microfabrication technology. This microgripper, which may be applied to trans-ducers or sensors, can be batch-fabricated in IC-compatible process. The movable mechanical elements are built onlayers that are later removed, so that they are free for translation and rotation. Under external driving, a microgrip-per cut from substrate would be able to catch tiny filament or small particle with dimension of 10~ 200 micrometers.

  14. Effect of thermally grown oxide (TGO) microstructure on the durability of TBCs with PtNiAl diffusion bond coats

    Energy Technology Data Exchange (ETDEWEB)

    Spitsberg, Irene [Materials and Process Engineering Department, GE Aircraft Engines, Evendale, OH (United States)]. E-mail: irene.spitsberg@kennametal.com; More, Karren [Metals and Ceramics Division, Oak Ridge National Laboratory, Oak Ridge, TN (United States)

    2006-02-15

    The role of pre-oxidation surface treatments on the oxide microstructure and the failure mechanism of multi-layer thermal barrier systems based on Pt-modified NiAl bond coats and electron beam deposited thermal barrier coatings (TBCs) have been studied. The primary pre-oxidation experimental variable was the partial pressure of oxygen in the pre-oxidizing atmosphere at constant temperature and bond coat composition. The durability of TBCs deposited on surfaces following different pre-oxidation treatments were measured and compared using furnace cycling tests. The oxide layers corresponding to different levels of TBC performance were characterized microstructurally, chemically, and compositionally using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) techniques. TBC performance was enhanced by the formation of a surface oxide having a coarse-grained columnar structure during the pre-oxidation process. Increased TBC durability was consistent with a slower oxide growth rate during exposure of the TBC to high-temperature, cyclic conditions, as was observed for this particular pre-oxidation condition. An oxide microstructure having fewer through-thickness transport pathways (grain boundaries) should also result in slower lateral oxide growth rates, consistent with a slowed rate of ratcheting as was observed in the pre-oxidized samples that had the best TBC performance. The desired surface oxide grain structure was achieved by pre-oxidizing the bond coat prior to TBC deposition at an intermediate partial pressure of oxygen.

  15. Practical Aspects of Suspension Plasma Spray for Thermal Barrier Coatings on Potential Gas Turbine Components

    Science.gov (United States)

    Ma, X.; Ruggiero, P.

    2018-04-01

    Suspension plasma spray (SPS) process has attracted extensive efforts and interests to produce fine-structured and functional coatings. In particular, thermal barrier coatings (TBCs) applied by SPS process gain increasing interest due to its potential for superior thermal protection of gas turbine hot sections as compared to conventional TBCs. Unique columnar architectures and nano- and submicrometric grains in the SPS-TBC demonstrated some advantages of thermal shock durability, low thermal conductivity, erosion resistance and strain-tolerant microstructure. This work aimed to look into some practical aspects of SPS processing for TBC applications before it becomes a reliable industry method. The spray capability and applicability of SPS process to achieve uniformity thickness and microstructure on curved substrates were emphasized in designed spray trials to simulate the coating fabrication onto industrial turbine parts with complex configurations. The performances of the SPS-TBCs were tested in erosion, falling ballistic impact and indentational loading tests as to evaluate SPS-TBC performances in simulated turbine service conditions. Finally, a turbine blade was coated and sectioned to verify SPS sprayability in multiple critical sections. The SPS trials and test results demonstrated that SPS process is promising for innovative TBCs, but some challenges need to be addressed and resolved before it becomes an economic and capable industrial process, especially for complex turbine components.

  16. Systems and methods for scalable perovskite device fabrication

    Science.gov (United States)

    Huang, Jinsong; Dong, Qingfeng; Sao, Yuchuan

    2017-02-28

    Continuous processes for fabricating a perovskite device are described that include using a doctor blade for continuously forming a perovskite layer and using a conductive tape lamination process to form an anode or a cathode layer on the perovskite device.

  17. Geometrical Modeling of Woven Fabrics Weavability-Limit New Relationships

    Directory of Open Access Journals (Sweden)

    Dalal Mohamed

    2017-03-01

    Full Text Available The weavability limit and tightness for 2D and 3D woven fabrics is an important factor and depends on many geometric parameters. Based on a comprehensive review of the literature on textile fabric construction and property, and related research on fabric geometry, a study of the weavability limit and tightness relationships of 2D and 3D woven fabrics was undertaken. Experiments were conducted on a representative number of polyester and cotton woven fabrics which have been woven in our workshop, using three machines endowed with different insertion systems (rapier, projectiles and air jet. Afterwards, these woven fabrics have been analyzed in the laboratory to determine their physical and mechanical characteristics using air permeability-meter and KES-F KAWABATA Evaluation System for Fabrics. In this study, the current Booten’s weavability limit and tightness relationships based on Ashenhurst’s, Peirce’s, Love’s, Russell’s, Galuszynskl’s theory and maximum-weavability is reviewed and modified as new relationships to expand their use to general cases (2D and 3D woven fabrics, all fiber materiel, all yarns etc…. The theoretical relationships were examined and found to agree with experimental results. It was concluded that the weavability limit and tightness relationships are useful tools for weavers in predicting whether a proposed fabric construction was weavable and also in predicting and explaining their physical and mechanical properties.

  18. Total body calcium by neutron activation analysis in normals and osteoporotic populations: a discriminator of significant bone mass loss

    International Nuclear Information System (INIS)

    Ott, S.M.; Murano, R.; Lewellen, T.K.; Nelp, W.B.; Chesnut, C.M.

    1983-01-01

    Measurements of total body calcium by neutron activation (TBC) in 94 normal individuals and 86 osteoporotic patients are reported. The ability of TBC to discriminate normal from osteoporotic females was evaluated with decision analysis. Bone mineral content (BMC) by single-photon absorptiometry was also measured. TBC was higher in males (range 826 to 1363 gm vs 537 to 1054 in females) and correlated with height in all normals. In females over age 55 there was a negative correlation with age. Thus, for normals an algorithm was derived to allow comparison between measured TBC and that predicted by sex, age, and height (TBCp). In the 28 normal females over age 55, the TBC was 764 +/- 115 gm vs. 616 +/- 90 in the osteoporotics. In 63 of the osteoporotic females an estimated height, from tibial length, was used to predict TBC. In normals the TBC/TBCp ratio was 1.00 +/- 0.12, whereas in osteoporotic females it was 0.80 +/- 0.12. A receiver operating characteristic curve showed better discrimination of osteoporosis with TBC/TBCp than with wrist BMC. By using Bayes' theorem, with a 25% prevalence of osteoporosis (estimate for postmenopausal women), the posttest probability of disease was 90% when the TBC/TBCp ratio was less than 0.84. The authors conclude that a low TBC/TBCp ratio is very helpful in determining osteoporosis

  19. Fabrication of subcutaneous veins phantom for vessel visualization system

    Science.gov (United States)

    Cheng, Kai; Narita, Kazuyuki; Morita, Yusuke; Nakamachi, Eiji; Honda, Norihiro; Awazu, Kunio

    2013-09-01

    The technique of subcutaneous veins imaging by using NIR (Near Infrared Radiation) is widely used in medical applications, such as the intravenous injection and the blood sampling. In the previous study, an automatic 3D blood vessel search and automatic blood sampling system was newly developed. In order to validate this NIR imaging system, we adopted the subcutaneous vein in the human arm and its artificial phantom, which imitate the human fat and blood vessel. The human skin and subcutaneous vein is characterized as the uncertainty object, which has the individual specificity, non-accurate depth information, non-steady state and hardly to be fixed in the examination apparatus. On the other hand, the conventional phantom was quite distinct from the human's characteristics, such as the non-multilayer structure, disagreement of optical property. In this study, we develop a multilayer phantom, which is quite similar with human skin, for improvement of NIR detection system evaluation. The phantom consists of three layers, such as the epidermis layer, the dermis layer and the subcutaneous fat layer. In subcutaneous fat layer, we built a blood vessel. We use the intralipid to imitate the optical scattering characteristics of human skin, and the hemoglobin and melanin for the optical absorption characteristics. In this study, we did two subjects. First, we decide the fabrication process of the phantom. Second, we compared newly developed phantoms with human skin by using our NIR detecting system, and confirm the availability of these phantoms.

  20. A trial fabrication of activity standard surface sources and positional standard surface sources for an imaging plate system

    International Nuclear Information System (INIS)

    Sato, Yasushi; Hino, Yoshio; Yamada, Takahiro; Matsumoto, Mikio

    2003-01-01

    An imaging plate system can detect low level activity, but quantitative analysis is difficult because there are no adequate standard surface sources. A new fabrication method was developed for standard surface sources by printing on a sheet of paper using an ink-jet printer with inks in which a radioactive material was mixed. The fabricated standard surface sources had high uniformity, high positional resolution arbitrary shapes and a broad intensity range. The standard sources were used for measurement of surface activity as an application. (H. Yokoo)

  1. Improved Fibroblast Functionalities by Microporous Pattern Fabricated by Microelectromechanical Systems

    Science.gov (United States)

    Wei, Hongbo; Zhao, Lingzhou; Chen, Bangdao; Bai, Shizhu; Zhao, Yimin

    2014-01-01

    Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10–60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structures with micropore diameters of 10–60 µm did not influence the initial adherent fibroblast number; however, those with diameters of 40 and 50 µm improved the spread, actin stress fiber organization, proliferation and fibronectin secretion of the fibroblasts. The microporous structures with micropore diameters of 40–50 µm may be promising for application in the percutaneous part of an implant. PMID:25054322

  2. Improved Fibroblast Functionalities by Microporous Pattern Fabricated by Microelectromechanical Systems

    Directory of Open Access Journals (Sweden)

    Hongbo Wei

    2014-07-01

    Full Text Available Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10–60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structures with micropore diameters of 10–60 µm did not influence the initial adherent fibroblast number; however, those with diameters of 40 and 50 µm improved the spread, actin stress fiber organization, proliferation and fibronectin secretion of the fibroblasts. The microporous structures with micropore diameters of 40–50 µm may be promising for application in the percutaneous part of an implant.

  3. Techniques for fabricating an infrared optical pyrometry system for pulsed electron beam diagnostics

    International Nuclear Information System (INIS)

    Ouellette, A.L.

    1976-01-01

    A description is given of an infrared optical pyrometry system which was designed to make fast time resolved temperature measurements. The purpose of this equipment is to determine the amount of energy from an electron beam or some other type of pulsed energy deposition that is absorbed in a target. The system is capable of measuring energy deposition levels up to 4000 J/g in carbon, which corresponds to a graphite target temperature of 2200 0 C. Methods of fabrication, alignment, and calibration are presented. The measurement of absorbed energy in a target as a function of position and depth is discussed as a possible application, and several measurements are described which permit a comparison of results from this system with those taken by other methods

  4. The data acquisition system for the management of nuclear materials involved in the fabrication of MOX fuel at the Cogema plant in Cadarache

    International Nuclear Information System (INIS)

    Crousilles, M.; Beche, M.; Dalverny, G.

    2001-01-01

    This article presents the follow-up system of all the nuclear materials that are involved in the industrial process of MOX fuel fabrication. This system, called Concerto, allows the management of MOX fabrication but also of any nuclear material transfer and of the stockpile of nuclear materials with taking into account their own specificity such as the risk of criticality. Operators that intervene on the different steps of the fabrication process, supply Concerto with information so Concerto can be considered as a near real-time system providing and recording the localization, the composition, the weight, the container,... of any batch of nuclear materials. Concerto complies with the requirements of quality assurance but also of nuclear safety by forbidding any transfer whenever the maximal authorized quantity would be exceeded. (A.C.)

  5. An automated method for the layup of fiberglass fabric

    Science.gov (United States)

    Zhu, Siqi

    This dissertation presents an automated composite fabric layup solution based on a new method to deform fiberglass fabric referred to as shifting. A layup system was designed and implemented using a large robotic gantry and custom end-effector for shifting. Layup tests proved that the system can deposit fabric onto two-dimensional and three-dimensional tooling surfaces accurately and repeatedly while avoiding out-of-plane deformation. A process planning method was developed to generate tool paths for the layup system based on a geometric model of the tooling surface. The approach is analogous to Computer Numerical Controlled (CNC) machining, where Numerical Control (NC) code from a Computer-Aided Design (CAD) model is generated to drive the milling machine. Layup experiments utilizing the proposed method were conducted to validate the performance. The results show that the process planning software requires minimal time or human intervention and can generate tool paths leading to accurate composite fabric layups. Fiberglass fabric samples processed with shifting deformation were observed for meso-scale deformation. Tow thinning, bending and spacing was observed and measured. Overall, shifting did not create flaws in amounts that would disqualify the method from use in industry. This suggests that shifting is a viable method for use in automated manufacturing. The work of this dissertation provides a new method for the automated layup of broad width composite fabric that is not possible with any available composite automation systems to date.

  6. Multicore optical fiber grating array fabrication for medical sensing applications

    Science.gov (United States)

    Westbrook, Paul S.; Feder, K. S.; Kremp, T.; Taunay, T. F.; Monberg, E.; Puc, G.; Ortiz, R.

    2015-03-01

    In this work we report on a fiber grating fabrication platform suitable for parallel fabrication of Bragg grating arrays over arbitrary lengths of multicore optical fiber. Our system exploits UV transparent coatings and has precision fiber translation that allows for quasi-continuous grating fabrication. Our system is capable of both uniform and chirped fiber grating array spectra that can meet the demands of medical sensors including high speed, accuracy, robustness and small form factor.

  7. Fabrication and Characterisation of Membrane-Based Gold Electrodes

    DEFF Research Database (Denmark)

    Bakmand, Tanya; Kwasny, Dorota; Dimaki, Maria

    2015-01-01

    This work presents a versatile, membrane based electrochemical sensor with thin film electrodes fabricated through Ebeam evaporation directly on porous materials (membranes). Here, the fabrication of the electrodes is described along with possible methods for integration in fluidic systems...

  8. In-process fault detection for textile fabric production: onloom imaging

    Science.gov (United States)

    Neumann, Florian; Holtermann, Timm; Schneider, Dorian; Kulczycki, Ashley; Gries, Thomas; Aach, Til

    2011-05-01

    Constant and traceable high fabric quality is of high importance both for technical and for high-quality conventional fabrics. Usually, quality inspection is carried out by trained personal, whose detection rate and maximum period of concentration are limited. Low resolution automated fabric inspection machines using texture analysis were developed. Since 2003, systems for the in-process inspection on weaving machines ("onloom") are commercially available. With these defects can be detected, but not measured quantitative precisely. Most systems are also prone to inevitable machine vibrations. Feedback loops for fault prevention are not established. Technology has evolved since 2003: Camera and computer prices dropped, resolutions were enhanced, recording speeds increased. These are the preconditions for real-time processing of high-resolution images. So far, these new technological achievements are not used in textile fabric production. For efficient use, a measurement system must be integrated into the weaving process; new algorithms for defect detection and measurement must be developed. The goal of the joint project is the development of a modern machine vision system for nondestructive onloom fabric inspection. The system consists of a vibration-resistant machine integration, a high-resolution machine vision system, and new, reliable, and robust algorithms with quality database for defect documentation. The system is meant to detect, measure, and classify at least 80 % of economically relevant defects. Concepts for feedback loops into the weaving process will be pointed out.

  9. Mesh joinery: a method for building fabricable structures

    OpenAIRE

    Cignoni, Paolo; Pietroni, Nico; Malomo, Luigi; Scopigno, Roberto

    2015-01-01

    Mesh joinery is an innovative method to produce illustrative shape approximations suitable for fabrication. Mesh joinery is capable of producing complex fabricable structures in an efficient and visually pleasing manner. We represent an input geometry as a set of planar pieces arranged to compose a rigid structure by exploiting an efficient slit mechanism. Since slices are planar, a standard 2D cutting system is sufficient to fabricate them.

  10. Degradation of Thermal Barrier Coatings from Deposits and Its Mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Nitin Padture

    2011-12-31

    Ceramic thermal barrier coatings (TBCs) used in gas-turbine engines afford higher operating temperatures, resulting in enhanced efficiencies and performance. However, in the case of syngas-fired engines, fly ash particulate impurities that may be present in syngas can melt on the hotter TBC surfaces and form glassy deposits. These deposits can penetrate the TBCs leading to their failure. In experiments using lignite fly ash to simulate these conditions we show that conventional TBCs of composition 93wt% ZrO{sub 2} + 7wt% Y{sub 2}O{sub 3} (7YSZ) fabricated using the air plasma spray (APS) process are completely destroyed by the molten fly ash. The molten fly ash is found to penetrate the full thickness of the TBC. The mechanisms by which this occurs appear to be similar to those observed in degradation of 7YSZ TBCs by molten calcium-magnesium-aluminosilicate (CMAS) sand and by molten volcanic ash in aircraft engines. In contrast, APS TBCs of Gd{sub 2Zr{sub 2}O{sub 7} composition are highly resistant to attack by molten lignite fly ash under identical conditions, where the molten ash penetrates ~25% of TBC thickness. This damage mitigation appears to be due to the formation of an impervious, stable crystalline layer at the fly ash/Gd{sub 2}Zr{sub 2}O{sub 7} TBC interface arresting the penetrating moltenfly- ash front. Additionally, these TBCs were tested using a rig with thermal gradient and simultaneous accumulation of ash. Modeling using an established mechanics model has been performed to illustrate the modes of delamination, as well as further opportunities to optimize coating microstructure. Transfer of the technology was developed in this program to all interested parties.

  11. Interlamellar cracking of thermal barrier coatings with TGOs by non-standard four-point bending tests

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, P.F. [State Key Laboratory for Strength and Vibration, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an (China); Li, X.D. [State Key Laboratory for Strength and Vibration, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an (China); Aircraft Strength Research Institute of China, Xi' an, 710065 (China); Shang, F.L., E-mail: shangfl@mail.xjtu.edu.cn [State Key Laboratory for Strength and Vibration, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an (China); Li, C.J. [State Key Laboratory for Mechanical Behavior of Materials, School of Materials Science and Engineering, Xi' an Jiaotong University, Xi' an (China)

    2011-09-25

    Highlights: {yields} A non-standard modified four-point bending specimen is adopted for delamination test. {yields} Typical failure mode of the TBC system with TGO layer is demonstrated. {yields} Fracture toughness of 8YSZ on a cold-sprayed MCrAlY coating is evaluated theoretically. - Abstract: This work concerns the failure mode and fracture toughness of plasma-sprayed 8 wt% yttria-stabilized zirconia (8YSZ) deposited on a cold-sprayed MCrAlY bond coat (BC) after thermal oxidation. Upon high-temperature exposure, a thermally grown oxide (TGO) layer was formed along the interface between the BC layer and YSZ ceramic coating layer through oxidation of the bond coat. By utilizing a non-standard modified four-point bending specimen, in conjunction with fractured surface examinations by scanning electron microscope and energy disperse spectroscope, the failure mode of this thermal barrier coating (TBC) system has been checked experimentally. It is shown that delamination cracks firstly initiate at the YSZ/BC interface edge, and then propagate along a wavy path near the interface, not only through the TBC but also within the TGO and along the interlamellar interfaces. Through a theoretical analysis of the bending specimen, the fracture toughness of this TBC system, in terms of strain energy release rate, has been determined from the load-displacement curves which were recorded during the tests.

  12. Microbial quality of bagged baby spinach and romaine lettuce: effects of top versus bottom sampling.

    Science.gov (United States)

    Kase, Julie A; Borenstein, Stacey; Blodgett, Robert J; Feng, Peter C H

    2012-01-01

    Contamination with Escherichia coli O157:H7 and Salmonella have called into question the safety and microbial quality of bagged ready-to-eat leafy greens. This study expands on previous findings that these goods have high total bacteria counts (TBC) and coliform counts, variation in counts among different lots, that Escherichia coli is present, and disparities in counts when bags are top or bottom sampled. Nearly 100 bags of baby spinach and hearts of romaine lettuce from a single brand were subjected to both top and bottom sampling. Product was blended, and a portion serially diluted and plated to obtain TBC. Total coliform and E. coli levels were estimated by the most-probable-number (MPN) technique with ColiComplete discs. Top-sampled TBC from bags of baby spinach (48 bags, 13 different lots) ranged from 3.9 to 8.1 log CFU/g and bottom-sampled TBC ranged from 4.0 to 8.2 log CFU/g, with 52% of the bags (or 39% of the lots) producing TBC higher in bottom samples. For hearts of romaine (47 bags from 19 different lots), top-sampled bags had TBC ranging from 2.4 to 7.0 log, and bottom-sampled bags had TBC from 3.3 to 7.3 log, with 64% of the bags (or 63% of the lots) showing higher TBC in bottom samples. However, we are unable to reject the hypothesis that the top and bottom samples from either commodity contain the same TBC (P ≥ 0.08). No E. coli was detected and total coliform bacteria counts were, with few exceptions, ≥210 MPN/g, irrespective of TBC. In general, lots with the most number of days before the printed "use-by" date had lower TBC. However, the R(2) values for either baby spinach (0.4085) or hearts of romaine (0.2946) suggest that age might not be a very good predictor of higher TBC. TBC varied widely between lots and even more so within same-lot samples, as indicated by the sum of squares results. This finding, along with higher TBC in bottom samples, suggests further consideration when a microbiological sampling scheme of bagged produce is

  13. Investigation into rationalization of low decontamination pellet fuel fabrication plant configuration

    International Nuclear Information System (INIS)

    Maekawa, Kazuhiko; Yoshimura, Tadahiro; Hoshino, Yasushi; Munekata, Hideki; Tamaki, Yoshihisa

    2005-02-01

    In feasibility studies on commercialized FBR cycle system, a comprehensive system investigation and properties evaluation for candidate FBR cycle systems has been implemented through view point of safety, economics, environmental burden reduction, non-proliferation resistivity, etc. As part of these studies, an investigation into rationalization of low decontamination pellet fuel fabrication plant configuration was carried out. Until last fiscal year, conceptual design studies of the fuel fabrication plant in 200t-HM/y scale were conducted, and system properties data concerning economics and environmental burden reduction of fuel fabrication plant was acquired. In addition to this, 50t-HM/y scale plant was also schematically studied. In this fiscal year, a rationalization study on conceptual design of 50t-HM/y scale plant was conducted with main aim of economic improvement, and the 200t-HM/y scale plant design was revised based on the recent R and D progress. The system properties data concerning economics and environmental burden reduction of fuel fabrication plant was also acquired. In both case of the 50t-HM/y and 200t-HM/y scale plant, it was suggested that the equipment costs were reduced in several percentages because of reduction of maintenance equipments and cut in line number at the pellet fabrication process although granulation process fro denitration converted powder and O/M control process for pellets were added. System properties data for comparative evaluation of candidate fuel fabrication systems was also prepared. (author)

  14. Development and validation of equations utilizing lamb vision system output to predict lamb carcass fabrication yields.

    Science.gov (United States)

    Cunha, B C N; Belk, K E; Scanga, J A; LeValley, S B; Tatum, J D; Smith, G C

    2004-07-01

    This study was performed to validate previous equations and to develop and evaluate new regression equations for predicting lamb carcass fabrication yields using outputs from a lamb vision system-hot carcass component (LVS-HCC) and the lamb vision system-chilled carcass LM imaging component (LVS-CCC). Lamb carcasses (n = 149) were selected after slaughter, imaged hot using the LVS-HCC, and chilled for 24 to 48 h at -3 to 1 degrees C. Chilled carcasses yield grades (YG) were assigned on-line by USDA graders and by expert USDA grading supervisors with unlimited time and access to the carcasses. Before fabrication, carcasses were ribbed between the 12th and 13th ribs and imaged using the LVS-CCC. Carcasses were fabricated into bone-in subprimal/primal cuts. Yields calculated included 1) saleable meat yield (SMY); 2) subprimal yield (SPY); and 3) fat yield (FY). On-line (whole-number) USDA YG accounted for 59, 58, and 64%; expert (whole-number) USDA YG explained 59, 59, and 65%; and expert (nearest-tenth) USDA YG accounted for 60, 60, and 67% of the observed variation in SMY, SPY, and FY, respectively. The best prediction equation developed in this trial using LVS-HCC output and hot carcass weight as independent variables explained 68, 62, and 74% of the variation in SMY, SPY, and FY, respectively. Addition of output from LVS-CCC improved predictive accuracy of the equations; the combined output equations explained 72 and 66% of the variability in SMY and SPY, respectively. Accuracy and repeatability of measurement of LM area made with the LVS-CCC also was assessed, and results suggested that use of LVS-CCC provided reasonably accurate (R2 = 0.59) and highly repeatable (repeatability = 0.98) measurements of LM area. Compared with USDA YG, use of the dual-component lamb vision system to predict cut yields of lamb carcasses improved accuracy and precision, suggesting that this system could have an application as an objective means for pricing carcasses in a value

  15. Design, fabrication, commissioning, and testing of a 250 g/s, 2-K helium cold compressor system

    International Nuclear Information System (INIS)

    V. Ganni; D. M. Arenius; B. S. Bevins; W. C. Chronis; J. D. Creel; J. D. Wilson Jr.

    2002-01-01

    In June 1999 the Thomas Jefferson National Accelerator Facility (TJNAF) Cryogenic Systems Group had completed the design, fabrication, and commissioning of a cold compressor system capable of pumping 250 g/s of 2-K helium vapor to a pressure above 1 bar. The 2-K cold box consists of five stages of centrifugal variable speed compressors with LN2 cooled drive motors and magnetic bearings, a plate fin heat exchanger, and an LN2 shield system. The new 2-K cold box (referred to as the SCN) was built as a redundant system to an existing four stage cold compressor SCM cold box that was commissioned in May 1994. The SCN has been in continuous service supporting the facility experiments since commissioning. This system has achieved a significant improvement in the total 2-K refrigeration system capacity and stability and has substantially increased the operating envelope both in cold compressor flow and operating pressure range. This paper describes the cold box configuration and the experience s in the design, fabrication, commissioning and performance evaluation. The capacity of the system for various operating pressures (0.040 to 0.025 bar at the load corresponding to a total compressor pressure ratio of 28 to 54) is presented. An effort is made to characterize the components and their operating data over the tested range. This includes the return side pressure drop in the distribution system, the heat exchanger, and the cold compressor characteristics. The system design parameters and their effects on performance are outlined

  16. Explicit Finite Element Modeling of Multilayer Composite Fabric for Gas Turbine Engine Containment Systems, Phase II. Part 2; Ballistic Impact Testing

    Science.gov (United States)

    Revilock, D. M.; Pereira, J. M.

    2009-01-01

    This report summarizes the ballistic impact testing that was conducted to provide validation data for the development of numerical models of blade-out events in fabric containment systems. The ballistic impact response of two different fiber materials - Kevlar(TradeName) 49 and Zylon(TradeName) AS (as spun) was studied by firing metal projectiles into dry woven fabric specimens using a gas gun. The shape, mass, orientation, and velocity of the projectile were varied and recorded. In most cases, the tests were designed so the projectile would perforate the specimen, allowing measurement of the energy absorbed by the fabric. The results for both Zylon and Kevlar presented here represent a useful set of data for the purposes of establishing and validating numerical models to predict the response of fabrics under conditions that simulate those of a jet engine blade-release situation. In addition, some useful empirical observations were made regarding the effects of projectile orientation and the relative performance of the different fabric materials.

  17. Design and fabrication of multimode interference couplers based on digital micro-mirror system

    Science.gov (United States)

    Wu, Sumei; He, Xingdao; Shen, Chenbo

    2008-03-01

    Multimode interference (MMI) couplers, based on the self-imaging effect (SIE), are accepted popularly in integrated optics. According to the importance of MMI devices, in this paper, we present a novel method to design and fabricate MMI couplers. A technology of maskless lithography to make MMI couplers based on a smart digital micro-mirror device (DMD) system is proposed. A 1×4 MMI device is designed as an example, which shows the present method is efficient and cost-effective.

  18. Fabrication Aware Form-finding

    DEFF Research Database (Denmark)

    Egholm Pedersen, Ole; Larsen, Niels Martin; Pigram, Dave

    2014-01-01

    This paper describes a design and construction method that combines two distinct material systems with fabrication aware form-finding and file-to-factory workflows. The method enables the fluent creation of complex materially efficient structures comprising high populations of geometrically uniqu...

  19. Utilization of process TEG for fabrication of HTS circuits

    International Nuclear Information System (INIS)

    Hato, T.; Okada, Y.; Maruyama, M.; Suzuki, H.; Wakana, H.; Adachi, S.; Kawabe, U.; Tanabe, K.

    2006-01-01

    We improved the fabrication process of high-temperature superconducting (HTS) sampler circuits with multilayer structures by utilizing a test elements group (TEG). Among a lot of difficulties in the HTS circuit fabrication process, loss of oxygen is one of the most significant problems. Since the film transition temperature (T c ) has a strong relationship with the resistance at room temperature, we fabricated a test pattern on the same wafer of the circuits and measured the resistance at room temperature by using a prober to estimate the T c of each layer. By introducing the measurement of the normal resistance after each process, we found better process conditions without a T c drop. Moreover, we constructed a low-temperature probing system, in which we can measure the junction TEG. The system enabled feedback of the fabrication condition soon after the junction process. The utilization of the process TEG contributed to reproducible fabrication of HTS circuits and that is a promising advance of the HTS circuit technology

  20. Fabrication of 3D Carbon Microelectromechanical Systems (C-MEMS).

    Science.gov (United States)

    Pramanick, Bidhan; Martinez-Chapa, Sergio O; Madou, Marc; Hwang, Hyundoo

    2017-06-17

    A wide range of carbon sources are available in nature, with a variety of micro-/nanostructure configurations. Here, a novel technique to fabricate long and hollow glassy carbon microfibers derived from human hairs is introduced. The long and hollow carbon structures were made by the pyrolysis of human hair at 900 °C in a N2 atmosphere. The morphology and chemical composition of natural and pyrolyzed human hairs were investigated using scanning electron microscopy (SEM) and electron-dispersive X-ray spectroscopy (EDX), respectively, to estimate the physical and chemical changes due to pyrolysis. Raman spectroscopy was used to confirm the glassy nature of the carbon microstructures. Pyrolyzed hair carbon was introduced to modify screen-printed carbon electrodes ; the modified electrodes were then applied to the electrochemical sensing of dopamine and ascorbic acid. Sensing performance of the modified sensors was improved as compared to the unmodified sensors. To obtain the desired carbon structure design, carbon micro-/nanoelectromechanical system (C-MEMS/C-NEMS) technology was developed. The most common C-MEMS/C-NEMS fabrication process consists of two steps: (i) the patterning of a carbon-rich base material, such as a photosensitive polymer, using photolithography; and (ii) carbonization through the pyrolysis of the patterned polymer in an oxygen-free environment. The C-MEMS/NEMS process has been widely used to develop microelectronic devices for various applications, including in micro-batteries, supercapacitors, glucose sensors, gas sensors, fuel cells, and triboelectric nanogenerators. Here, recent developments of a high-aspect ratio solid and hollow carbon microstructures with SU8 photoresists are discussed. The structural shrinkage during pyrolysis was investigated using confocal microscopy and SEM. Raman spectroscopy was used to confirm the crystallinity of the structure, and the atomic percentage of the elements present in the material before and after

  1. Fabrication and characterization of injection molded multi level nano and microfluidic systems

    DEFF Research Database (Denmark)

    Matteucci, Marco; Christiansen, Thomas Lehrmann; Tanzi, Simone

    2013-01-01

    We here present a method for fabrication of multi-level all-polymer chips by means of silicon dry etching, electroplating and injection molding. This method was used for successful fabrication of microfluidic chips for applications in the fields of electrochemistry, cell trapping and DNA elongati...

  2. Manufacturing processes in the textile industry. Expert Systems for fabrics production

    Directory of Open Access Journals (Sweden)

    Juan BULLON

    2017-03-01

    Full Text Available The textile industry is characterized by the economic activity whose objective is the production of fibres, yarns, fabrics, clothing and textile goods for home and decoration,as well as technical and industrial purposes. Within manufacturing, the Textile is one of the oldest and most complex sectors which includes a large number of sub-sectors covering the entire production cycle, from raw materials and intermediate products, to the production of final products. Textile industry activities present different subdivisions, each with its own traits. The length of the textile process and the variety of its technical processes lead to the coexistence of different sub-sectors in regards to their business structure and integration. The textile industry is developing expert systems applications to increase production, improve quality and reduce costs. The analysis of textile designs or structures includes the use of mathematical models to simulate the behavior of the textile structures (yarns, fabrics and knitting. The Finite Element Method (FEM has largely facilitated the prediction of the behavior of that textile structure under mechanical loads. For classification problems Artificial Neural Networks (ANNs haveproved to be a very effective tool as a quick and accurate solution. The Case-Based Reasoning (CBR method proposed in this study complements the results of the finite element simulation, mathematical modeling and neural networks methods.

  3. Inspection logistics planning for multi-stage production systems with applications to semiconductor fabrication lines

    Science.gov (United States)

    Chen, Kyle Dakai

    Since the market for semiconductor products has become more lucrative and competitive, research into improving yields for semiconductor fabrication lines has lately received a tremendous amount of attention. One of the most critical tasks in achieving such yield improvements is to plan the in-line inspection sampling efficiently so that any potential yield problems can be detected early and eliminated quickly. We formulate a multi-stage inspection planning model based on configurations in actual semiconductor fabrication lines, specifically taking into account both the capacity constraint and the congestion effects at the inspection station. We propose a new mixed First-Come-First-Serve (FCFS) and Last-Come-First-Serve (LCFS) discipline for serving the inspection samples to expedite the detection of potential yield problems. Employing this mixed FCFS and LCFS discipline, we derive approximate expressions for the queueing delays in yield problem detection time and develop near-optimal algorithms to obtain the inspection logistics planning policies. We also investigate the queueing performance with this mixed type of service discipline under different assumptions and configurations. In addition, we conduct numerical tests and generate managerial insights based on input data from actual semiconductor fabrication lines. To the best of our knowledge, this research is novel in developing, for the first time in the literature, near-optimal results for inspection logistics planning in multi-stage production systems with congestion effects explicitly considered.

  4. Smart fabric sensors and e-textile technologies: a review

    International Nuclear Information System (INIS)

    Castano, Lina M; Flatau, Alison B

    2014-01-01

    This paper provides a review of recent developments in the rapidly changing and advancing field of smart fabric sensor and electronic textile technologies. It summarizes the basic principles and approaches employed when building fabric sensors as well as the most commonly used materials and techniques used in electronic textiles. This paper shows that sensing functionality can be created by intrinsic and extrinsic modifications to textile substrates depending on the level of integration into the fabric platform. The current work demonstrates that fabric sensors can be tailored to measure force, pressure, chemicals, humidity and temperature variations. Materials, connectors, fabric circuits, interconnects, encapsulation and fabrication methods associated with fabric technologies prove to be customizable and versatile but less robust than their conventional electronics counterparts. The findings of this survey suggest that a complete smart fabric system is possible through the integration of the different types of textile based functional elements. This work intends to be a starting point for standardization of smart fabric sensing techniques and e-textile fabrication methods. (topical review)

  5. Design and fabrication of microwave flat lenses using a novel dry powder dot deposition system

    International Nuclear Information System (INIS)

    Good, Brandon L; Roper, David A Jr; Simmons, Shaun; Mirotznik, Mark S

    2015-01-01

    We describe a new methodology for creating flat lenses operating in the microwave spectrum using a custom designed additive manufacturing system. This method utilizes a novel dry powder 3D printing system to achieve graded index lenses integrated within a structural composite. We also describe a new iterative dot patterning algorithm to achieve a desired graded dielectric distribution, and we compare the iterative dot patterning algorithm to other dot patterning techniques. Computational and experimental results are provided validating the design and fabrication process. (paper)

  6. Photolithography diagnostic expert systems: a systematic approach to problem solving in a wafer fabrication facility

    Science.gov (United States)

    Weatherwax Scott, Caroline; Tsareff, Christopher R.

    1990-06-01

    One of the main goals of process engineering in the semiconductor industry is to improve wafer fabrication productivity and throughput. Engineers must work continuously toward this goal in addition to performing sustaining and development tasks. To accomplish these objectives, managers must make efficient use of engineering resources. One of the tools being used to improve efficiency is the diagnostic expert system. Expert systems are knowledge based computer programs designed to lead the user through the analysis and solution of a problem. Several photolithography diagnostic expert systems have been implemented at the Hughes Technology Center to provide a systematic approach to process problem solving. This systematic approach was achieved by documenting cause and effect analyses for a wide variety of processing problems. This knowledge was organized in the form of IF-THEN rules, a common structure for knowledge representation in expert system technology. These rules form the knowledge base of the expert system which is stored in the computer. The systems also include the problem solving methodology used by the expert when addressing a problem in his area of expertise. Operators now use the expert systems to solve many process problems without engineering assistance. The systems also facilitate the collection of appropriate data to assist engineering in solving unanticipated problems. Currently, several expert systems have been implemented to cover all aspects of the photolithography process. The systems, which have been in use for over a year, include wafer surface preparation (HMDS), photoresist coat and softbake, align and expose on a wafer stepper, and develop inspection. These systems are part of a plan to implement an expert system diagnostic environment throughout the wafer fabrication facility. In this paper, the systems' construction is described, including knowledge acquisition, rule construction, knowledge refinement, testing, and evaluation. The roles

  7. Relationship between the Physical Properties and Hand of Jean Fabric

    Directory of Open Access Journals (Sweden)

    Kawamura Atsushi

    2016-09-01

    Full Text Available We investigated the distinctive characteristics of jean fabrics (denim fabrics obtained from jeans and compared the physical properties and the hand. We used 13 kinds of jean fabric from commercial jeans and 26 other fabric types. The physical properties were measured using the Kawabata evaluation system, and the fabric hand was evaluated by 20 subjects using a semantic differential method. To characterise the hand of jean fabrics compared with other fabrics, we used principal component analysis and obtained three principal components. We found that jean fabrics were characterised by the second principal component, which was affected by feelings of thickness and weight. We further characterised the jean fabrics according to ‘softness & smoothness’ and ‘non-fullness’, depending on country of origin and type of manufacturer. The three principal components were analysed using multiple linear regression to characterise the components according to the physical properties. We explained the hand of fabrics including jean fabrics using its association with physical properties.

  8. Design and Fabrication of a 5-kWe Free-Piston Stirling Power Conversion System

    Science.gov (United States)

    Chapman, Peter A.; Walter, Thomas J.; Brandhorst, Henry W., Jr.

    2008-01-01

    Progress in the design and fabrication of a 5-kWe free-piston Stirling power conversion system is described. A scaled-down version of the successful 12.5-kWe Component Test Power Converter (CTPC) developed under NAS3-25463, this single cylinder prototype incorporates cost effective and readily available materials (steel versus beryllium) and components (a commercial linear alternator). The design consists of a displacer suspended on internally pumped gas bearings and a power piston/alternator supported on flexures. Non-contacting clearance seals are used between internal volumes. Heat to and from the prototype is supplied via pumped liquid loops passing through shell and tube heat exchangers. The control system incorporates several novel ideas such as a pulse start capability and a piston stroke set point control strategy that provides the ability to throttle the engine to match the required output power. It also ensures stable response to various disturbances such as electrical load variations while providing useful data regarding the position of both power piston and displacer. All design and analysis activities are complete and fabrication is underway. Prototype test is planned for summer 2008 at Foster-Miller to characterize the dynamics and steady-state operation of the prototype and determine maximum power output and system efficiency. Further tests will then be performed at Auburn University to determine start-up and shutdown characteristics and assess transient response to temperature and load variations.

  9. Micro fabrication of biodegradable polymer drug delivery devices

    DEFF Research Database (Denmark)

    Nagstrup, Johan

    The pharmaceutical industry is presently facing several obstacles in developing oral drug delivery systems. This is primarily due to the nature of the discovered drug candidates. The discovered drugs often have poor solubility and low permeability across the gastro intestinal epithelium. Furtherm......The pharmaceutical industry is presently facing several obstacles in developing oral drug delivery systems. This is primarily due to the nature of the discovered drug candidates. The discovered drugs often have poor solubility and low permeability across the gastro intestinal epithelium...... permeability and degradation. These systems are for the majority based on traditional materials used in micro technology, such as SU-8, silicon, poly(methyl methacrylate). The next step in developing these new drug delivery systems is to replace classical micro fabrication materials with biodegradable polymers....... In order to successfully do this, methods for fabricating micro structures in biodegradable polymers need to be developed. The goal of this project has been to develop methods for micro fabrication in biodegradable polymers and to use these methods to produce micro systems for oral drug delivery. This has...

  10. The quality challenge for fuel fabrication

    International Nuclear Information System (INIS)

    Lannegrace, J.-P.

    1990-01-01

    Fuel fabrication is a key segment of the nuclear fuel cycle, since safe and economic operation of reactors is highly dependent on the quality of the fuel. Achieving and controlling quality is, therefore, of paramount importance to fuel fabricators dominating nearly every aspect of the business. The quality policy, concepts and assurance system at three French plants are outlined. The need for integrated inspection, process optimization and good employee motivation is stressed. (author)

  11. Microfluidic Fabrication Solutions for Tailor-Designed Fiber Suspensions

    Directory of Open Access Journals (Sweden)

    Helene Berthet

    2016-11-01

    Full Text Available Fibers are widely used in different industrial processes, for example in paper manufacturing or lost circulation problems in the oil industry. Recently, interest towards the use of fibers at the microscale has grown, driven by research in bio-medical applications or drug delivery systems. Microfluidic systems are not only directly relevant for lab-on-chip applications, but have also proven to be good model systems to tackle fundamental questions about the flow of fiber suspensions. It has therefore become necessary to provide fiber-like particles with an excellent control of their properties. We present here two complementary in situ methods to fabricate controlled micro-fibers allowing for an embedded fabrication and flow-on-a-chip platform. The first one, based on a photo-lithography principle, can be used to make isolated fibers and dilute fiber suspensions at specific locations of interest inside a microchannel. The self-assembly property of super-paramagnetic colloids is the principle of the second fabrication method, which enables the fabrication of concentrated suspensions of more flexible fibers. We propose a flow gallery with several examples of fiber flow illustrating the two methods’ capabilities and a range of recent laminar flow results.

  12. Fabrication and installment of hard-wired I and C works for the neutral beam injection system of the KSTAR project

    International Nuclear Information System (INIS)

    Jung, Ki Sok; Oh, Byung Hun; In, Sang Ryul; Yoon, Jae Sung

    2004-01-01

    Instrumentation and Control(I and C) of the neutral beam injection(NBI) system for the K-STAR national fusion research project has been working from the start of the project to answer diverse requests arising from various facets of the development and construction phases of the project. In a parallel effort with the software oriented I and C development, there has been existing an enormous amount of hard-wiring I and C works for the NBI facility to be developed and fabricated in schedule. Circuits and hardwired functions have been designed, tested, fabricated, and finally installed to the relevant parts of the system. Some examples of those hard-wired I and C works are related to the vacuum system, gas feeding system, arc detector circuit, ion source monitoring, bending magnet and calorimeter. They are one of those integral parts for the proper operation of the NBI system. Examples of those hard-wired I and C works are introduced in this presentation

  13. FabricS: A user-friendly, complete and robust software for particle shape-fabric analysis

    Science.gov (United States)

    Moreno Chávez, G.; Castillo Rivera, F.; Sarocchi, D.; Borselli, L.; Rodríguez-Sedano, L. A.

    2018-06-01

    Shape-fabric is a textural parameter related to the spatial arrangement of elongated particles in geological samples. Its usefulness spans a range from sedimentary petrology to igneous and metamorphic petrology. Independently of the process being studied, when a material flows, the elongated particles are oriented with the major axis in the direction of flow. In sedimentary petrology this information has been used for studies of paleo-flow direction of turbidites, the origin of quartz sediments, and locating ignimbrite vents, among others. In addition to flow direction and its polarity, the method enables flow rheology to be inferred. The use of shape-fabric has been limited due to the difficulties of automatically measuring particles and analyzing them with reliable circular statistics programs. This has dampened interest in the method for a long time. Shape-fabric measurement has increased in popularity since the 1980s thanks to the development of new image analysis techniques and circular statistics software. However, the programs currently available are unreliable, old and are incompatible with newer operating systems, or require programming skills. The goal of our work is to develop a user-friendly program, in the MATLAB environment, with a graphical user interface, that can process images and includes editing functions, and thresholds (elongation and size) for selecting a particle population and analyzing it with reliable circular statistics algorithms. Moreover, the method also has to produce rose diagrams, orientation vectors, and a complete series of statistical parameters. All these requirements are met by our new software. In this paper, we briefly explain the methodology from collection of oriented samples in the field to the minimum number of particles needed to obtain reliable fabric data. We obtained the data using specific statistical tests and taking into account the degree of iso-orientation of the samples and the required degree of reliability

  14. Fabrication of a Transparent Anti-stain Thin Film Using an Atmospheric Pressure Cold Plasma Deposition System

    Directory of Open Access Journals (Sweden)

    Suzaki Y.

    2013-08-01

    Full Text Available Recently, outdoor-constructed solar panels have a problem such as power generation efficiency is reduced by the face plate dirt. On the other hand, electronic touch panels have a problem such as deterioration of visibility of the screen by finger grease stain. To solve these problems, we need to fabricate the anti-stain surfaces which have superhydrophobic and oil-repellent abilities without spoiling the transparency of the transparent substrate. In this study, we fabricated lotus leaves like surface on a glass substrate. Firstly, SiO2 particles of ca. 100 nm diameter were arranged on the glass substrates. Secondly, to obtain the fractal-like structure (ultra-micro-rough structure on the surface, ZnO thin film having a columnar structure was fabricated on the SiO2 particles by using an atmospheric pressure cold plasma deposition system. By using these processes, the ZnO columns formed radiantly on the spherical surface of the SiO2 particles. Furthermore, without spoiling the ultra-micro-rough structure, a transparent anti-stain monolayer with low surface energy was prepared by using a chemical adsorption technique onto the surface. Average value of the water droplet contact angles of the samples fabricated was 151.8 deg. Field emission scanning electron microscope (FE-SEM observation reviled that this sample has a raspberry structure in which columnar structure has grown radially on the SiO2 particles.

  15. Structural Component Fabrication and Characterization of Advanced Radiation Resistant ODS Steel for Next Generation Nuclear Systems

    International Nuclear Information System (INIS)

    Noh, Sang Hoon; Kim, Young Chun; Jin, Hyun Ju; Choi, Byoung Kwon; Kang, Suk Hoon; Kim, Tae Kyu

    2016-01-01

    In a sodium-cooled fast reactor (SFR), the coolant outlet temperature and peak temperature of the fuel cladding tube will be about 545 .deg. C and 700 .deg. C with 250 dpa of a very high neutron dose rate. To realize this system, it is necessary to develop an advanced structural material having high creep and irradiation resistance at high temperatures. Austenitic stainless steel may be one of the candidates because of good strength and corrosion resistance at the high temperatures, however irradiation swelling severely occurred to 120dpa at high temperatures and this eventually leads to a decrease of the mechanical properties and dimensional stability. Advanced radiation resistant ODS steel (ARROS) has been newly developed for the in-core structural components in SFR, which has very attractive microstructures to achieve both superior creep and radiation resistances at high temperatures [4]. Nevertheless, the use of ARROS as a structural material essentially requires the fabrication technology development for component parts such as sheet, plate and tube. In this study, plates and tubes were tentatively fabricated with a newly developed alloy, ARROS. Microstructures as well as mechanical properties were also investigated to determine the optimized condition of the fabrication processes.

  16. Insights on the High-Temperature Operational Limits of ZrO2-Y2O3 TBCs Manufactured via Air Plasma Spray

    Science.gov (United States)

    Lima, Rogerio S.; Marple, Basil R.

    2017-03-01

    The effective high-temperature operation limit of a ZrO2-7-8 wt.%Y2O3 (YSZ) thermal barrier coating (TBC) manufactured via air plasma spray (APS) is considered to be 1300 °C. This is related to the metastable tetragonal t'-phase formed during the rapid quenching of the YSZ particles during spraying. The t'-phase transforms into the equilibrium tetragonal and cubic phases at temperatures ≥ 1300 °C, which can lead to the formation of the monoclinic phase of YSZ upon cooling to room temperature. This formation of the monoclinic phase is accompanied by a volume expansion that leads to TBC failure due to extensive micro-cracking. To further investigate this limitation, an APS YSZ TBC was sprayed on a CMSX-4 substrate. By using a thermal (laser) gradient cyclic testing, a temperature gradient was generated across the TBC/substrate system. The YSZ T- front and substrate backside T- back temperature levels were 1500 and 1000 °C, respectively. In cycle conditions (5-min or 1-h hot and 2-min cool), no TBC failure has been observed. This behavior was partially attributed to the unexpected absence of the monoclinic phase of the YSZ in the cycled coatings. Although preliminary, these results are promising regarding increasing the effective high-temperature operational limits of APS YSZ TBCs.

  17. Effects of management practices on yield and quality of milk from smallholder dairy units in urban and peri-urban Morogoro, Tanzania.

    Science.gov (United States)

    Gillah, Kejeri A; Kifaro, George C; Madsen, Jorgen

    2014-10-01

    A longitudinal study design was used to assess the management, chemical composition of cows' milk and quantify the microbial load of raw milk produced at farm level. Data were collected between December 2010 and September 2011 in Morogoro municipality. Milk samples were collected once every month and analysed for butter fat (BF), crude protein (CP), total solids (TS) and solids non-fat (SNF). Total bacterial count (TBC) and coliform counts (CC) were normalized by log transformation. The average milk yield was 7.0 l/day and was not influenced by feeding systems and breeds. Dairy cows owned by people who had no regular income produced more milk than government employees and retired officers. Means of BF, TS, SNF and CP were similar in different feeding systems. Wet season had significantly higher TBC (5.9 log10 cfu/ml) and CC (2.4 log10 cfu/ml) but feeding systems had no effect. Stocking density influenced TBC but not CC. It can be concluded that dairy cows produced low milk yield and its quality was poor.

  18. Fabrication of superhydrophobic cotton fabrics using crosslinking polymerization method

    Science.gov (United States)

    Jiang, Bin; Chen, Zhenxing; Sun, Yongli; Yang, Huawei; Zhang, Hongjie; Dou, Haozhen; Zhang, Luhong

    2018-05-01

    With the aim of removing and recycling oil and organic solvent from water, a facile and low-cost crosslinking polymerization method was first applied on surface modification of cotton fabrics for water/oil separation. Micro-nano hierarchical rough structure was constructed by triethylenetetramine (TETA) and trimesoyl chloride (TMC) that formed a polymeric layer on the surface of the fabric and anchored Al2O3 nanoparticles firmly between the fabric surface and the polymer layer. Superhydrophobic property was further obtained through self-assembly grafting of hydrophobic groups on the rough surface. The as-prepared cotton fabric exhibited superoleophilicity in atmosphere and superhydrophobicity both in atmosphere and under oil with the water contact angle of 153° and 152° respectively. Water/oil separation test showed that the as-prepared cotton fabric can handle with various oil-water mixtures with a high separation efficiency over 99%. More importantly, the separation efficiency remained above 98% over 20 cycles of reusing without losing its superhydrophobicity which demonstrated excellent reusability in oil/water separation process. Moreover, the as-prepared cotton fabric possessed good contamination resistance ability and self-cleaning property. Simulation washing process test showed the superhydrophobic cotton fabric maintained high value of water contact angle above 150° after 100 times washing, indicating great stability and durability. In summary, this work provides a brand-new way to surface modification of cotton fabric and makes it a promising candidate material for oil/water separation.

  19. Modelling, fabrication and characterisation of THz fractal meta-materials

    DEFF Research Database (Denmark)

    Xiao, S.; Zhou, L.; Malureanu, Radu

    2011-01-01

    We present theoretical predictions, fabrication procedure and characterisation results of fractal metamaterials for the THz frequency range. The characterisation results match well the predicted response thus validating both the fabrication procedure as well as the simulation one. Such systems sh...

  20. Production planning and control for semiconductor wafer fabrication facilities modeling, analysis, and systems

    CERN Document Server

    Mönch, Lars; Mason, Scott J

    2012-01-01

    Over the last fifty-plus years, the increased complexity and speed of integrated circuits have radically changed our world. Today, semiconductor manufacturing is perhaps the most important segment of the global manufacturing sector. As the semiconductor industry has become more competitive, improving planning and control has become a key factor for business success. This book is devoted to production planning and control problems in semiconductor wafer fabrication facilities. It is the first book that takes a comprehensive look at the role of modeling, analysis, and related information systems

  1. Nanolithographic Fabrication and Heterogeneous Reaction Studies ofTwo-Dimensional Platinum Model Catalyst Systems

    Energy Technology Data Exchange (ETDEWEB)

    Contreras, Anthony Marshall [Univ. of California, Berkeley, CA (United States)

    2006-05-20

    In order to better understand the fundamental components that govern catalytic activity, two-dimensional model platinum nanocatalyst arrays have been designed and fabricated. These catalysts arrays are meant to model the interplay of the metal and support important to industrial heterogeneous catalytic reactions. Photolithography and sub-lithographic techniques such as electron beam lithography, size reduction lithography and nanoimprint lithography have been employed to create these platinum nanoarrays. Both in-situ and ex-situ surface science techniques and catalytic reaction measurements were used to correlate the structural parameters of the system to catalytic activity.

  2. Fabrication of semi-transparent superoleophobic thin film from fabrics and nanoparticle-based hierarchical structure

    Directory of Open Access Journals (Sweden)

    Nishizawa S.

    2013-08-01

    Full Text Available Superoleophobic thin films have many potential applications including fluid transfer, fluid power systems, stain resistant and antifouling materials, and microfluidics among others. Transparency is also desired with superhydrophobicity for their numerous applications; however transparency and oleophobicity are almost incompatible relationship with each other in the point of surface structure. Because oleophobicity required rougher structure at nano-micro scale than hydrophobicity, and these rough structure brings light scattering. So far, there is very few report of the compatible of transparency and superoleophobicity. In this report, we proposed the see-through type fabrics using the nanoparticle-based hierarchical structure thin film for improving both of oleophobicity and transparency. The vacant space between fibrils of fabrics has two important roles: the one is to through the light, another one is to introduce air layer to realize Cassie state of liquid droplet on thin film. To realize the low surface energy and nanoscale rough structure surface on fibrils, we used the spray method with perfluoroalkyl methacrylic copolymer (PMC, silica nano particles and volatile solvent. From the SEM image, the hierarchical structures of nanoparticle were formed uniformly on the fabrics. The transparency of thin film obtained was approximately 61% and the change of transparency between pre-coated fabrics and coated was 11%. From investigation of the surface wettability, the contact angles of oils (rapeseed oil and hexadecane and water droplet on the fabricated film were over 150 degree.

  3. INFLUENCE OF FABRIC TIGHTNESS ON SPIRALITY OF WEFTKNITTED PLAIN COTTON FABRIC

    Directory of Open Access Journals (Sweden)

    A.K.M. Mobarok Hossain

    2011-01-01

    Full Text Available Global demand for knitted garments is growing at a faster rate than that of woven items.Currently around 50% of clothing needs in the developed countries is met by knit goods. So ensuring the required quality in a knitted fabric is a vital issue for the manufacturer. One of the major problems encountered in knitted fabric is spirality. It affects particularly single jersey fabric and presents a serious problem during garment confection and use. So controlling spirality is a basic requirement for producing quality knitted fabric. Though there are several factors that contribute to knitted fabric spirality, yarn twist and relative tightness of the fabric are said tobe the most significant ones. In this work the basic single jersey fabric, i.e. plain jersey cotton fabrics were produced by a Hosiery knitting machine and spirality values were observed for different yarn T.P.I. and tightness factor at relaxed state. It was found that tightness factor has a direct influence on knitted fabric spirality with a high degree of correlation. The work thus gives an idea to deal this problem by controlling the knitting parameters.

  4. Program plan for the Brayton Isotope Power System. Phase I. Design, fabrication and test of the Brayton Isotope Power System

    International Nuclear Information System (INIS)

    1975-01-01

    Phase I of an overall program for the development of a 500 to 2000 W(e) (EOM), 7-y life, power system for space vehicles is discussed. The system uses a closed Brayton dynamic system to convert energy from an isotope heat source at a net efficiency greater than 25 percent. This first phase, a 35-month effort, is for the conceptual design of a 1300 W(e), 450 lb flight system and the design, fabrication, and test of a ground demonstration system. The flight system will use, for the baseline design, two of the multihundred-watt (MHW) heat sources being developed. The Ground Demonstration System will simulate, as closely as possible, the Brayton Isotope Power Flight System and will utilize components and technology being developed for the Mini-Brayton rotating unit, recuperator and heat source assembly, respectively. The Ground Demonstration System includes a performance test and a 1000-h endurance test

  5. Research on plant of metal fuel fabrication using casting process

    International Nuclear Information System (INIS)

    Senda, Yasuhide; Mori, Yukihide

    2003-12-01

    This document presents the plant concept of metal fuel fabrication system (38tHM/y) using casting process in electrolytic recycle, which based on recent studies of its equipment design and quality control system. And we estimate the cost of its construction and operation, including costs of maintenance, consumed hardware and management of waste. The content of this work is as follows. (1) Designing of fuel fabrication equipment: We make material flow diagrams of the fuel fabrication plant and rough designs of the injection casting furnace, demolder and inspection equipment. (2) Designing of resolution system of liquid waste, which comes from analytical process facility. Increased analytical items, we rearrange analytical process facility, estimate its chemicals and amount of waste. (3) Arrangement of equipments: We made a arrangement diagram of the metal fuel fabrication equipments in cells. (4) Estimation of cost data: We estimated cost to construct the facility and to operate it. (author)

  6. OpenSoC Fabric

    Energy Technology Data Exchange (ETDEWEB)

    2014-08-21

    Recent advancements in technology scaling have shown a trend towards greater integration with large-scale chips containing thousands of processors connected to memories and other I/O devices using non-trivial network topologies. Software simulation proves insufficient to study the tradeoffs in such complex systems due to slow execution time, whereas hardware RTL development is too time-consuming. We present OpenSoC Fabric, an on-chip network generation infrastructure which aims to provide a parameterizable and powerful on-chip network generator for evaluating future high performance computing architectures based on SoC technology. OpenSoC Fabric leverages a new hardware DSL, Chisel, which contains powerful abstractions provided by its base language, Scala, and generates both software (C++) and hardware (Verilog) models from a single code base. The OpenSoC Fabric2 infrastructure is modeled after existing state-of-the-art simulators, offers large and powerful collections of configuration options, and follows object-oriented design and functional programming to make functionality extension as easy as possible.

  7. Design, fabrication and commissioning of motorized scanning bed mechanism for shadow shield whole body counting system

    International Nuclear Information System (INIS)

    Arun, B.; Varalakshimi, S.; Manohari, M.; Mathiyarasu, R.

    2012-01-01

    A new scanning bed mechanism for shadow shield counting system is designed, fabricated and commissioned at RSD, IGCAR. The present motorized scanning bed mechanism has varying scan speeds, state of art limit sensors, smooth bed movement, touch screen based software controlled operation parameters with UPS power back-up. In view of the improved personnel safety the entire system has been designed to operate with low voltage power supply (24V). The evaluation demonstrated that the incorporation of the new motorized scanning mechanism has not affected the counting performance of the shadow shield wholebody counting system. (author)

  8. Clinical and radiological comparison of tuberculous and pyogenic spondylitis. An analysis of 49 operated cases

    International Nuclear Information System (INIS)

    Dzelzite, S.; Maurins, G.

    1998-01-01

    Objective: To perform retrospective analysis of 49 operated patients with histologically proven spondylodiscitis of tbc and pyogenic origin. Patient histories, laboratory tests and radiographic findings were statistically compared between two groups. We estimated that in 16 cases (32.6%) origin of spondylodiscitis was tbc and 33 cases (67.4%) origin was pyogenic. All cases of tbc spondylitis (except one drug resistant tbc form) were with previously proved tbc diagnosis of different localisation. Radiological findings for the tbc cases were more than two-vertebra involvement and deformation of vertebral column axis. Pyogenic spondylodiscitis (33 cases) were derived from or after - 1. lumbal discectomies (7 cases), 2. operation on retroperitoneal cavity (6 cases) including 3 cases after prothesation of abdominal aorta, 3. closed spine trauma (4 cases), 4. hematogenic dissemination of pyogenic infection from different localisation - kidney, lung, sinuses (8 cases). In 8 cases we did not estimate potential cause of spondylodiscitis. Conclusion: A definite diagnosis of spondylodiscitis was established by means of biopsy, histological evidence and bacterial culture. There are not specific radiological findings to differentiate tbc spondylodiscitis from pyogenic spondylodiscitis. (Full text)

  9. Printing and Curing of Conductive Ink Track on Fabric using Syringe Deposition System with DLP Projector and Hot Plate

    Directory of Open Access Journals (Sweden)

    Khirotdin Rd. Khairilhijra

    2017-01-01

    Full Text Available Printing is a technique to transfer ink onto substrates to create pattern and syringe deposition system has shown some great potential in printing due to its ability to produce filamentary bead tracks which is important concerning conductivity and easily adopted on conformal surfaces which could not be realized by conventional technique. Fabrics with integrated electrical features able to create intelligent articles and may potentially open up new perspective areas of application in textile printing. However, the applicability of this technique on fabrics remains unknown which the ink used has to meet certain requirements including high electrical conductivity, resistance to oxidation, dry out without clogging, good adhesion with suitable viscosity and surface tension. Thus, there is a need to do this study which is to determine the feasibility of syringe deposition system to print a conductive ink tracks using silver epoxy-based conductive ink on fabric substrate via lycra material. This study is also aim to investigate the feasibility of using DLP projector with hot plate as another source of heat to be used in curing the ink tracks on fabric. The effect of printing and curing parameters to the characteristics and conductivity of the ink track is investigated. Several mechanical and electrical tests were also administered to determine the cure, hardness, adhesion and resistance level of the ink tracks. The results obtained were as expected which higher printing speed and lower deposition height used, a narrower and thinner ink tracks were produced. Sample with 4 mm/s of printing speed and deposition height of 1 mm resulted in dimension closer to the targeted dimension. The longer curing time and higher temperature used, a lower resistance is produced. The lowest resistance achieved is 0.9 Ω cured at 150°C for 60 minutes. The conductivity of the ink track was affected by curing process and cross-sectional area of the ink track. It is proven

  10. Facile fabrication of a superhydrophobic fabric with mechanical stability and easy-repairability.

    Science.gov (United States)

    Zhu, Xiaotao; Zhang, Zhaozhu; Yang, Jin; Xu, Xianghui; Men, Xuehu; Zhou, Xiaoyan

    2012-08-15

    The poor mechanical stability of superhydrophobic fabrics severely hindered their use in practical applications. Herein, to address this problem, we fabricated a superhydrophobic fabric with both mechanical stability and easy-repairability by a simple method. The mechanical durability of the obtained superhydrophobic fabric was evaluated by finger touching and abrasion with sandpaper. The results show that rough surface textures of the fabric were retained, and the fabric surface still exhibited superhydrophobicity after tests. More importantly, when the fabric lost its superhydrophobicity after a long-time abrasion, it can be easily rendered with superhydrophobicity once more by a regeneration process. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Compact, Wearable Antennas for Battery-Less Systems Exploiting Fabrics and Magneto-Dielectric Materials

    Directory of Open Access Journals (Sweden)

    Alessandra Costanzo

    2014-08-01

    Full Text Available In this paper, we describe some promising solutions to the modern need for wearable, energy-aware, miniaturized, wireless systems, whose typical envisaged application is a body area network (BAN. To reach this goal, novel materials are adopted, such as fabrics, in place of standard substrates and metallizations, which require a systematic procedure for their electromagnetic characterization. Indeed, the design of such sub-systems represents a big issue, since approximate approaches could result in strong deviations from the actual system performance. To face this problem, we demonstrate our design procedure, which is based on the concurrent use of electromagnetic software tools and nonlinear circuit-level techniques, able to simultaneously predict the actual system behavior of an antenna system, consisting of the radiating and of the nonlinear blocks, at the component level. This approach is demonstrated for the design of a fully-wearable tri-band rectifying antenna (rectenna and of a button-shaped, electrically-small antenna deploying a novel magneto-dielectric substrate. Simulations are supported by measurements, both in terms of antenna port parameters and far-field results.

  12. Analysis, fabrication, and field test of an advanced embedded throwing electromechanical sensing system

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Zhen; Zhang, Dan [Beijing JiaoTong University, Beijing (China)

    2014-01-15

    Scientific measuring equipment is important in maintaining and further improving the daily training quality of professional athletes. In throwing sports, only kinematic information is usually recorded by several high-speed cameras, whereas the dynamic data are lacking. An advanced embedded throwing system is analyzed, fabricated, and field tested. This throwing system can be used to substitute the normal shot-put that obtains acceleration information from the upper limb when force is applied onto the device. This device has four main parts, namely, a mechanical shell, an embedded sensor, a signal processing circuit, and interface ports. The detailed design, simulation, and prototyping process are introduced in this work. The practical results obtained from the field test and feedback from users prove that the proposed throwing system is efficient for technical training and monitoring. This design provides a unique solution for the modeling and development of non-traditional, electro-mechanical sensing devices.

  13. Mechanical Properties of Porous Titanium Structure Fabricated by Investment Casting with Pressurization/Depressurization System

    International Nuclear Information System (INIS)

    Kang, San; Lee, Ji-Woon; Hyun, Soong-Keun; Lee, Byong-Pil; Kim, Myoung-Gyun; Kim, Young-Jig

    2014-01-01

    A porous titanium structure was fabricated by investment casting with a pressurization/depressurization system, and its mechanical properties were studied. A Micro-Vickers hardness profile revealed that hardness gradually increased from the matrix to the metal/mold interface. A compression test was conducted on a single cell of the porous Ti structure. The theoretical and experimental values of yield strength were in good agreement. Such agreement suggested that the reaction layer did not affect the macro-mechanical properties of the porous Ti structure.

  14. Methods for Fabricating Gradient Alloy Articles with Multi-Functional Properties

    Science.gov (United States)

    Hofmann, Douglas C. (Inventor); Borgonia, John Paul C. (Inventor); Dillon, Robert P. (Inventor); Suh, Eric J. (Inventor); Mulder, Jerry L. (Inventor); Gardner, Paul B. (Inventor)

    2015-01-01

    Systems and methods for fabricating multi-functional articles comprised of additively formed gradient materials are provided. The fabrication of multi-functional articles using the additive deposition of gradient alloys represents a paradigm shift from the traditional way that metal alloys and metal/metal alloy parts are fabricated. Since a gradient alloy that transitions from one metal to a different metal cannot be fabricated through any conventional metallurgy techniques, the technique presents many applications. Moreover, the embodiments described identify a broad range of properties and applications.

  15. Stirling Microregenerators Fabricated and Tested

    Science.gov (United States)

    Moran, Matthew E.

    2004-01-01

    A mesoscale Stirling refrigerator patented by the NASA Glenn Research Center is currently under development. This refrigerator has a predicted efficiency of 30 percent of Carnot and potential uses in electronics, sensors, optical and radiofrequency systems, microarrays, and microsystems. The mesoscale Stirling refrigerator is most suited to volume-limited applications that require cooling below the ambient or sink temperature. Primary components of the planar device include two diaphragm actuators that replace the pistons found in traditional-scale Stirling machines and a microregenerator that stores and releases thermal energy to the working gas during the Stirling cycle. Diaphragms are used to eliminate frictional losses and bypass leakage concerns associated with pistons, while permitting reversal of the hot and cold sides of the device during operation to allow precise temperature control. Three candidate microregenerators were fabricated under NASA grants for initial evaluation: two constructed of porous ceramic, which were fabricated by Johns Hopkins Applied Physics Laboratory, and one made of multiple layers of nickel and photoresist, which was fabricated by Polar Thermal Technologies. The candidate regenerators are being tested by Johns Hopkins Applied Physics in a custom piezoelectric-actuated test apparatus designed to produce the Stirling refrigeration cycle. In parallel with the regenerator testing, Johns Hopkins is using deep reactive ion etching to fabricate electrostatically driven, comb-drive diaphragm actuators. These actuators will drive the Stirling cycle in the prototype device. The top photograph shows the porous ceramic microregenerators. Two microregenerators were fabricated with coarse pores and two with fine pores. The bottom photograph shows the test apparatus parts for evaluating the microregenerators, including the layered nickel-and-photoresist regenerator fabricated using LIGA techniques.

  16. Design and fabrication of Si-HDPE hybrid Fresnel lenses for infrared imaging systems.

    Science.gov (United States)

    Manaf, Ahmad Rosli Abdul; Sugiyama, Tsunetoshi; Yan, Jiwang

    2017-01-23

    In this work, novel hybrid Fresnel lenses for infrared (IR) optical applications were designed and fabricated. The Fresnel structures were replicated from an ultraprecision diamond-turned aluminum mold to an extremely thin layer (tens of microns) of high-density polyethylene polymer, which was directly bonded onto a flat single-crystal silicon wafer by press molding without using adhesives. Night mode imaging results showed that the fabricated lenses were able to visualize objects in dark fields with acceptable image quality. The capability of the lenses for thermography imaging was also demonstrated. This research provides a cost-effective method for fabricating ultrathin IR optical components.

  17. Fabrication, Physicochemical Characterization, and Performance Evaluation of Biodegradable Polymeric Microneedle Patch System for Enhanced Transcutaneous Flux of High Molecular Weight Therapeutics.

    Science.gov (United States)

    Shah, Viral; Choudhury, Bijaya Krushna

    2017-11-01

    A revolutionary paradigm shift is being observed currently, towards the use of therapeutic biologics for disease management. The present research was focused on designing an efficient dosage form for transdermal delivery of α-choriogonadotropin (high molecular weight biologic), through biodegradable polymeric microneedles. Polyvinylpyrrolidone-based biodegradable microneedle arrays loaded with high molecular weight polypeptide, α-choriogonadotropin, were fabricated for its systemic delivery via transdermal route. Varied process and formulation parameters were optimized for fabricating microneedle array, which in turn was expected to temporally rupture the stratum corneum layer of the skin, acting as a major barrier to drug delivery through transdermal route. The developed polymeric microneedles were optimized on the basis of quality attributes like mechanical strength, axial strength, insertion ratio, and insertion force analysis. The optimized polymeric microneedle arrays were characterized for in vitro drug release studies, ex vivo drug permeation studies, skin resealing studies, and in vivo pharmacokinetic studies. Results depicted that fabricated polymeric microneedle arrays with mechanical strength of above 5 N and good insertion ratio exhibited similar systemic bioavailability of α-choriogonadotropin in comparison to marketed subcutaneous injection formulation of α-choriogonadotropin. Thus, it was ultimately concluded that the designed drug delivery system can serve as an efficient tool for systemic delivery of therapeutic biologics, with an added benefit of overcoming the limitations of parenteral delivery, achieving better patient acceptability and compliance.

  18. Evaluation of the Marginal Fit of CAD/CAM Crowns Fabricated Using Two Different Chairside CAD/CAM Systems on Preparations of Varying Quality.

    Science.gov (United States)

    Renne, Walter; Wolf, Bethany; Kessler, Raymond; McPherson, Karen; Mennito, Anthony S

    2015-01-01

    This study evaluated the marginal gap of crowns fabricated using two new chairside computer-aided design/computer-aided manufacturing systems on preparations completed by clinicians with varying levels of expertise to identify whether common preparation errors affect marginal fit. The null hypothesis is that there is no difference in the mean marginal gaps of restorations of varying qualities and no difference in the mean marginal gap size between restorations fabricated using the PlanScan (D4D, Richardson, TX, USA) and the CEREC Omnicam (Sirona, Bensheim, Germany). The fit of 80 lithium disilicate crowns fabricated with the E4D PlanScan or CEREC Omnicam systems on preparations of varying quality were examined for marginal fit by using the replica technique. These same preparations were then visually examined against common criteria for anterior all-ceramic restorations and placed in one of four categories: excellent, good, fair, and poor. Linear mixed modeling was used to evaluate associations between marginal gap, tooth preparation rating, and fabrication machine. The fit was not significantly different between both systems across all qualities of preparation. The average fit was 104 μm for poor-quality preparations, 87.6 μm for fair preparations, 67.2 μm for good preparations, and 36.6 μm for excellent preparations. The null hypothesis is rejected. It can be concluded that preparation quality has a significant impact on marginal gap regardless of which system is used. However, no significant difference was found when comparing the systems to each other. Within the limitations of this in vitro study, it can be concluded that crown preparation quality has a significant effect on marginal gap of the restoration when the clinician uses either CEREC Omnicam or E4D PlansScan. © 2015 Wiley Periodicals, Inc.

  19. Espectro clínico de tuberculosis cutánea Clinic spectrum of cutaneous tuberculosis

    Directory of Open Access Journals (Sweden)

    G Pizzariello

    2008-09-01

    Full Text Available La Tuberculosis (TBC es producida por el Mycobacterium tuberculosis o bacilo de Koch, y se ha observado en las últimas décadas, una reemergencia de casos pulmonares y extrapulmonares. La TBC cutánea es infrecuente, y presenta un amplio espectro clínico dependiendo del interjuego existente entre el agente, el huésped y el ambiente. TBC cutánea, ilustrándola con casos clínicos de pacientes que concurrieron a nuestro servicio.Tuberculosis (TBC is caused by Mycobacterium tuberculosis or Koch's bacillus, and there was a re-emergence of pulmonary and extrapulmonary cases in the last decades. Cutaneous TBC is uncommon, there is a broad clinical spectrum and an interrelationship between the agent, the guest and the environment. A description of each form of cutaneous TBC was made, illustrating it with clinical cases of patients who were attended in our service.

  20. Predator-scent stress, ethanol consumption and the opioid system in an animal model of PTSD.

    Science.gov (United States)

    Manjoch, Hadar; Vainer, Ella; Matar, Michael; Ifergane, Gal; Zohar, Joseph; Kaplan, Zeev; Cohen, Hagit

    2016-06-01

    Emerging literature points to stress exposure as a potential contributor to the development of alcohol abuse, but animal models have yielded inconsistent results. Converging experimental data indicate that the endogenous opioid system modulates alcohol consumption and stress regulation. The aim of the present study is to examine the interplay between stress exposure, behavioral stress responses, ethanol (EtOH) consumption and the endogenous opioid system in an animal model of posttraumatic stress disorder. Rats were exposed to stress and then tested in a two-bottle free choice (TBC) assay or in a conditioned place preference paradigm. In some experiments, the endogenous opioid system was pharmacologically manipulated prior to stress exposure. The behavioral outcomes of stress exposure were assessed in an elevated plus-maze, with the acoustic startle response, and by monitoring the freezing response to trauma reminder. Immunoreactivity of phosphorylated opioid receptors in hippocampal subregions was also measured. Stress significantly increased the consumption of EtOH in the TBC assay. The severity of the behavioral response to stress was associated with EtOH consumption, cue-triggered freezing response to a trauma reminder, and endogenous levels of phosphorylated opioid receptors in the hippocampus. Pharmacologically manipulating the endogenous opioid system prior to stress exposure attenuated trauma cue-triggered freezing responses and blocked predator scent stress-induced potentiation of EtOH consumption. These data demonstrate a stress-induced potentiation of EtOH self-administration and reveal a clear association between individual patterns of the behavioral response to stress and alcohol preference, while indicating a role for the endogenous opioid system in the neurobiological response to stress. Copyright © 2016. Published by Elsevier B.V.

  1. Precise Morphology Control and Continuous Fabrication of Perovskite Solar Cells Using Droplet-Controllable Electrospray Coating System.

    Science.gov (United States)

    Hong, Seung Chan; Lee, Gunhee; Ha, Kyungyeon; Yoon, Jungjin; Ahn, Namyoung; Cho, Woohyung; Park, Mincheol; Choi, Mansoo

    2017-03-08

    Herein, we developed a novel electrospray coating system for continuous fabrication of perovskite solar cells with high performance. Our system can systemically control the size of CH 3 NH 3 PbI 3 precursor droplets by modulating the applied electrical potential, shown to be a crucial factor for the formation of perovskite films. As a result, we have obtained pinhole-free and large grain-sized perovskite solar cells, yielding the best PCE of 13.27% with little photocurrent hysteresis. Furthermore, the average PCE through the continuous coating process was 11.56 ± 0.52%. Our system demonstrates not only the high reproducibility but also a new way to commercialize high-quality perovskite solar cells.

  2. Fabric circuits and method of manufacturing fabric circuits

    Science.gov (United States)

    Chu, Andrew W. (Inventor); Dobbins, Justin A. (Inventor); Scully, Robert C. (Inventor); Trevino, Robert C. (Inventor); Lin, Greg Y. (Inventor); Fink, Patrick W. (Inventor)

    2011-01-01

    A flexible, fabric-based circuit comprises a non-conductive flexible layer of fabric and a conductive flexible layer of fabric adjacent thereto. A non-conductive thread, an adhesive, and/or other means may be used for attaching the conductive layer to the non-conductive layer. In some embodiments, the layers are attached by a computer-driven embroidery machine at pre-determined portions or locations in accordance with a pre-determined attachment layout before automated cutting. In some other embodiments, an automated milling machine or a computer-driven laser using a pre-designed circuit trace as a template cuts the conductive layer so as to separate an undesired portion of the conductive layer from a desired portion of the conductive layer. Additional layers of conductive fabric may be attached in some embodiments to form a multi-layer construct.

  3. Delamination evaluation of thermal barrier coating on turbine blade owing to isothermal degradation using ultrasonic C-scan image

    International Nuclear Information System (INIS)

    Lee, Ho Girl; Kim, Hak Joon; Song, Sung Jin; Seok, Chang Sung

    2016-01-01

    Thermal barrier coating (TBC) is an essential element consisting of a super-alloy base and ceramic coating designed to achieve long operational time under a high temperature and pressure environment. However, the top coat of TBC can be delaminated at certain temperatures with long operation time. As the delamination of TBC is directly related to the blade damage, the coupling status of the TBC should be assured for reliable operation. Conventional studies of nondestructive evaluation have been made for detecting generation of thermally grown oxide (TGO) or qualitatively evaluating delamination in TBC. In this study, the ultrasonic C-scan method was developed to obtain the damage map inside TBC by estimating the delamination in a quantitative way. All specimens were isothermally degraded at 1,100°C with different time, having different partial delamination area. To detect partial delamination in TBC, the C-scan was performed by a single transducer using pulse-echo method with normal incidence. Partial delamination coefficients of 1 mm to 6 mm were derived by the proportion of the surface reflection signal and flaw signal which were theoretical signals using Rogers-Van Buren and Kim's equations. Using the partial delamination coefficients, the partial delamination maps were obtained. Regardless of the partial delamination coefficient, partial delamination area was increased when degradation time was increased in TBC. In addition, a decrease in partial delamination area in each TBC specimen was observed when the partial delamination coefficient was increased. From the portion of the partial delamination maps, the criterion for delamination was derived

  4. Delamination evaluation of thermal barrier coating on turbine blade owing to isothermal degradation using ultrasonic C-scan image

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ho Girl; Kim, Hak Joon; Song, Sung Jin; Seok, Chang Sung [Dept. of Mechanical Engineering, Sungkyunkwan University, Suwon (Korea, Republic of)

    2016-10-15

    Thermal barrier coating (TBC) is an essential element consisting of a super-alloy base and ceramic coating designed to achieve long operational time under a high temperature and pressure environment. However, the top coat of TBC can be delaminated at certain temperatures with long operation time. As the delamination of TBC is directly related to the blade damage, the coupling status of the TBC should be assured for reliable operation. Conventional studies of nondestructive evaluation have been made for detecting generation of thermally grown oxide (TGO) or qualitatively evaluating delamination in TBC. In this study, the ultrasonic C-scan method was developed to obtain the damage map inside TBC by estimating the delamination in a quantitative way. All specimens were isothermally degraded at 1,100°C with different time, having different partial delamination area. To detect partial delamination in TBC, the C-scan was performed by a single transducer using pulse-echo method with normal incidence. Partial delamination coefficients of 1 mm to 6 mm were derived by the proportion of the surface reflection signal and flaw signal which were theoretical signals using Rogers-Van Buren and Kim's equations. Using the partial delamination coefficients, the partial delamination maps were obtained. Regardless of the partial delamination coefficient, partial delamination area was increased when degradation time was increased in TBC. In addition, a decrease in partial delamination area in each TBC specimen was observed when the partial delamination coefficient was increased. From the portion of the partial delamination maps, the criterion for delamination was derived.

  5. Fabrication Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Fabrication Facilities are a direct result of years of testing support. Through years of experience, the three fabrication facilities (Fort Hood, Fort Lewis, and...

  6. Fabrication and Scale-up of Polybenzimidazole (PBI) Membrane Based System for Precombustion-Based Capture of Carbon Dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Krishnan, Gopala; Jayaweera, Indira; Sanjrujo, Angel; O' Brien, Kevin; Callahan, Richard; Berchtold, Kathryn; Roberts, Daryl-Lynn; Johnson, Will

    2012-03-31

    The primary objectives of this project are to (1) demonstrate the performance and fabrication of a technically and economically viable pre-combustion-based CO{sub 2} capture system based on the high temperature stability and permeance of PBI membranes, (2) optimize a plan for integration of PBI capture system into an IGCC plant and (3) develop a commercialization plan that addresses technical issues and business issues to outline a clear path for technology transfer of the PBI membrane technology. This report describes research conducted from April 1, 2007 to March 30, 2012 and focused on achieving the above objectives. PBI-based hollow fibers have been fabricated at kilometer lengths and bundled as modules at a bench-scale level for the separation of CO{sub 2} from H{sub 2} at high temperatures and pressures. Long term stability of these fibers has been demonstrated with a relatively high H{sub 2}/CO{sub 2} selectivity (35 to 50) and H{sub 2} permeance (80 GPU) at temperatures exceeding 225°C. Membrane performance simulations and systems analysis of an IGCC system incorporating a PBI hollow fiber membrane modules have demonstrated that the cost of electricity for CO{sub 2} capture (<10%) using such a high temperature separator. When the cost of transporting, storing, and monitoring the CO{sub 2} is accounted for, the increase in the COE is only 14.4%.

  7. DIGITAL DETECTION SYSTEM DESIGN OF MYCOBACTERIUM TUBERCULOSIS THROUGH EXTRACTION OF SPUTUM IMAGE USING NEURAL NETWORK METHOD

    Directory of Open Access Journals (Sweden)

    Franky Arisgraha

    2012-01-01

    Full Text Available Tuberculosis (TBC is an dangerous disease and many people has been infected. One of many important steps to control TBC effectively and efficiently is by increasing case finding using right method and accurate diagnostic. One of them is to detect Mycobacterium Tuberculosis inside sputum. Conventional detection of Mycobacterium Tuberculosis inside sputum can need a lot of time, so digitally detection method of Mycobacterium Tuberculosis was designed as an effort to get better result of detection. This method was designed by using combination between digital image processing method and Neural Network method. From testing report that was done, Mycobacterium can be detected with successful value reach 77.5% and training error less than 5%.

  8. Design and fabrication of a biomimetic gyroscope inspired by the fly's haltere

    NARCIS (Netherlands)

    Droogendijk, H.; Brookhuis, Robert Anton; de Boer, Meint J.; Sanders, Remco G.P.; Krijnen, Gijsbertus J.M.

    2012-01-01

    We report on the design and fabrication of a MEMS-based gyroscopic system inspired by the fly's haltere system. Two types of so-called biomimetic gyroscopes have been designed, fabricated and their drive mode has been characterized. First measurements indicate excitable gyropscopes with natural

  9. Fique Fabric: A Promising Reinforcement for Polymer Composites

    Directory of Open Access Journals (Sweden)

    Sergio Neves Monteiro

    2018-02-01

    Full Text Available A relatively unknown natural fiber extracted from the leaves of the fique plant, native of the South American Andes, has recently shown potential as reinforcement of polymer composites for engineering applications. Preliminary investigations indicated a promising substitute for synthetic fibers, competing with other well-known natural fibers. The fabric made from fique fibers have not yet been investigated as possible composite reinforcement. Therefore, in the present work a more thorough characterization of fique fabric as a reinforcement of composites with a polyester matrix was performed. Thermal mechanical properties of fique fabric composites were determined by dynamic mechanical analysis (DMA. The ballistic performance of plain woven fique fabric-reinforced polyester matrix composites was investigated as a second layer in a multilayered armor system (MAS. The results revealed a sensible improvement in thermal dynamic mechanical behavior. Both viscoelastic stiffness and glass transition temperature were increased with the amount of incorporated fique fabric. In terms of ballistic results, the fique fabric composites present a performance similar to that of the much stronger KevlarTM as an MAS second layer with the same thickness. A cost analysis indicated that armor vests with fique fabric composites as an MAS second layer would be 13 times less expensive than a similar creation made with Kevlar™.

  10. Barium ferrite/epoxy resin nanocomposite system: Fabrication, dielectric, magnetic and hydration studies

    Directory of Open Access Journals (Sweden)

    A. Kanapitsas

    2016-03-01

    Full Text Available Composite systems of epoxy resin and barium ferrite nanoparticles have been prepared, and studied varying the content of the inclusions. Morphology of prepared samples has been examined via scanning electron microscopy and X-ray diffraction spectra, while electrical and magnetic properties were investigated by means of broadband dielectric spectroscopy, and magnetization tests respectively. Finally, water vapor sorption measurements were conducted in order to study the water sorption dynamics of the system. Electron microscopy images revealed the successful fabrication of nanocomposites. Dielectric permittivity increases with filler content, while three relaxation processes were detected in the relative spectra. These processes are attributed to interfacial polarization, glass to rubber transition of the matrix, and re-orientation of polar side groups of the polymer’s chain. Magnetization and magnetic saturation increase with magnetic nano-powder content. Nanocomposites absorb a small amount of water, not exceeding 1.7 wt%, regardless filler content, indicating their hydrophobic character.

  11. An evaluation of marginal fit of three-unit fixed dental prostheses fabricated by direct metal laser sintering system.

    Science.gov (United States)

    Kim, Ki-Baek; Kim, Woong-Chul; Kim, Hae-Young; Kim, Ji-Hwan

    2013-07-01

    This in vitro study aimed to evaluate and compare marginal fit of three-unit fixed dental prostheses (FDPs) fabricated using a newly developed direct metal laser sintering (DMLS) system with that of three-unit FDPs by a conventional lost wax technique (LW) method. Ten cobalt-chromium alloy three-unit FDPs using DMLS system and another ten nickel-chromium alloy FDPs using LW method were fabricated. Marginal fit was examined using a light-body silicone. After setting, the silicon film was cut into four parts and the thickness of silicon layer was measured at 160× magnification using a digital microscope to measure absolute marginal discrepancy (AMD), marginal gap (MG) and internal gap (IG). A repeated measure ANOVA for statistical analysis was performed using the SPSS statistical package version 12.0 (α=0.05). The mean values of AMD, MG, and IG were significantly larger in the DMLS group than in the LW group (p0.05). The marginal fit of the DMLS system appeared significantly inferior compared to that of the conventional LW method and slightly larger than the acceptable range. For clinical application further improvement of DMLS system may be required. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  12. Evaluation of magnetostrictive composite coated fabric as a fragment barrier material

    International Nuclear Information System (INIS)

    Son, Kwon Joong; Fahrenthold, Eric P

    2012-01-01

    Over the last decade a surge in fragment barrier research has led to investigation of numerous materials and material augmentations in the attempt to improve the ballistic performance of systems designed to protect personnel, vehicles or infrastructure from impact and blast loads. One widely studied material augmentation approach is the use of coatings, often polymers, to enhance the performance of protection systems constructed from metal, concrete, composite and fabric materials. In recent research the authors have conducted the first experimental study of the ballistic performance of fabrics coated with a magnetically responsive polymer. Zero field impact experiments on coated fabric targets showed a 61% increase in impact energy dissipation, although the coated targets were not competitive with neat fabrics on a protection per unit mass basis. Under an applied field of 110 kA m −1 , the ballistic performance of the coated fabric was reduced. The reduction in performance may be attributed to a reduction in material damping and an increase in material modulus for the magnetostrictive component of the coating. Analysis of the coated fabric response to magnetic preloads suggests that coating tensile stresses and coating–fabric interface stresses induced by the applied field may also adversely affect ballistic performance. (paper)

  13. Design and development on automated control system of coated fuel particle fabrication process

    International Nuclear Information System (INIS)

    Liu Malin; Shao Youlin; Liu Bing

    2013-01-01

    With the development trend of the large-scale production of the HTR coated fuel particles, the original manual control system can not meet the requirement and the automation control system of coated fuel particle fabrication in modern industrial grade is needed to develop. The comprehensive analysis aiming at successive 4-layer coating process of TRISO type coated fuel particles was carried out. It was found that the coating process could be divided into five subsystems and nine operating states. The establishment of DCS-type (distributed control system) of automation control system was proposed. According to the rigorous requirements of preparation process for coated particles, the design considerations of DCS were proposed, including the principle of coordinated control, safety and reliability, integration specification, practical and easy to use, and open and easy to update. A complete set of automation control system for coated fuel particle preparation process was manufactured based on fulfilling the requirements of these principles in manufacture practice. The automated control system was put into operation in the production of irradiated samples for HTRPM demonstration project. The experimental results prove that the system can achieve better control of coated fuel particle preparation process and meet the requirements of factory-scale production. (authors)

  14. Engineering Design and Fabrication of an Ampere-Class Superconducting Photocathode Electron Gun

    International Nuclear Information System (INIS)

    Ben-Zvi, I.

    2008-01-01

    Over the past three years, Advanced Energy Systems and Brookhaven National Laboratory (BNL) have been collaborating on the design of an Ampere- class superconducting photocathode electron gun. BNL performed the physics design of the overall system and RF cavity under prior programs. Advanced Energy Systems (AES) is currently responsible for the engineering design and fabrication of the electron gun under contract to BNL. We will report on the engineering design and fabrication status of the superconducting photocathode electron gun. The overall configuration of the cryomodule will be reviewed. The layout of the hermitic string, space frame, shielding package, and cold mass will be discussed. The engineering design of the gun cavity and removable cathode will be presented in detail and areas of technical risk will be highlighted. Finally, the fabrication sequence and fabrication status of the gun cavity will be discussed

  15. Mathematical modeling of the gas and powder flow in the (HVOF) systems to optimize their coatings quality

    Science.gov (United States)

    Tawfik, Hazem H.

    1996-01-01

    Thermally sprayed coatings have been extensively used to enhance materials properties and provide surface protection against their working environments in a number of industrial applications. Thermal barrier coatings (TBC) are used to reduce the thermal conductivity of aerospace turbine blades and improve the turbine overall thermal efficiency. TBC allows higher gas operating temperatures and lower blade material temperatures due to the thermal insulation provided by these ceramic coatings. In the automotive industry, coatings are currently applied to a number of moving parts that are subjected to friction and wear inside the engine such as pistons, cylinder liners, valves and crankshafts to enhance their wear resistance and prolong their useful operation and lifetime.

  16. Espectro clínico de tuberculosis cutánea Clinic spectrum of cutaneous tuberculosis

    OpenAIRE

    G Pizzariello; P Fernández Pardal; G D´Atri; V Novac; A Uranga

    2008-01-01

    La Tuberculosis (TBC) es producida por el Mycobacterium tuberculosis o bacilo de Koch, y se ha observado en las últimas décadas, una reemergencia de casos pulmonares y extrapulmonares. La TBC cutánea es infrecuente, y presenta un amplio espectro clínico dependiendo del interjuego existente entre el agente, el huésped y el ambiente. TBC cutánea, ilustrándola con casos clínicos de pacientes que concurrieron a nuestro servicio.Tuberculosis (TBC) is caused by Mycobacterium tuberculosis or Koch's ...

  17. Fabrication of HTTR first loading fuel

    International Nuclear Information System (INIS)

    Kato, S.; Yoshimuta, S.; Hasumi, T.; Sato, K.; Sawa, K.; Suzuki, S.; Mogi, H.; Shiozawa, S.; Tanaka, T.

    2001-01-01

    This paper summarizes the fabrication of the first loading fuel for HTTR, High Temperature engineering Test Reactor constructed by JAERI, Japan Atomic Energy Research Institute. The fuel fabrication started at the HTR fuel facility of NFI, Nuclear Fuel Industries, Ltd., June 1995. 4,770 fuel rods were fabricated through the fuel kernel, coated fuel particle and fuel compaction process, then 150 fuel elements were assembled in the reactor building December 1997. Fabrication technology for the fuel was established through a lot of R and D activities and fabrication experience of irradiation examination samples spread over about 30 years. Most of all, very high quality and production efficiency of fuel were achieved by the development of the fuel kernel process using the vibration dropping technology, the continuous 4-layer coating process and the automatic compaction process. As for the inspection technology, the development of the automatic measurement equipment for coated layer thickness of a coated fuel particle and uranium content of a fuel compact contributed to the higher reliability and rationalization of the inspection process. The data processing system for the fabrication and quality control, which was originally developed by NFI, made possible not only quick feedback of statistical quality data to the fabrication processes, but also automatic document preparation, such as inspection certificates and accountability control reports. The quality of the first loading fuel fully satisfied the design specifications for the fuel. In particular, average bare uranium fraction and SiC defective fraction of fuel compacts were 2x10 -6 and 8x10 -5 , respectively. According to the preceding irradiation examinations being performed at JMTR, Japan Materials Testing Reactor of JAERI, the specimen sampled from the first loading fuel shows good irradiation performance. (author)

  18. Kinematics of Mass Transport Deposits revealed by magnetic fabrics

    Science.gov (United States)

    Weinberger, R.; Levi, T.; Alsop, G. I.; Marco, S.

    2017-08-01

    The internal deformation and movement directions of Mass Transport Deposits (MTDs) are key factors in understanding the kinematics and dynamics of their emplacement. Although these are relatively easy to recover from well-bedded sediments, they are more difficult to deduce from massive beds without visible strain markers. In order to test the applicability of using anisotropy of magnetic susceptibility (AMS) to determine MTD movement, we compare AMS fabrics, with structural measurements of visible kinematic indicators. Our case study involves the structural analysis of slumped lake sediments extensively exposed in MTDs within the Dead Sea Basin. Structural analyses of MTDs outcropping for >100 km reveal radial transport directions toward the basin depocenter. We show that the AMS fabrics display the same transport directions as inferred from structural analyses. Based on this similarity, we outline a robust procedure to obtain the transport direction of slumped MTDs from AMS fabrics. Variations in the magnetic fabrics and anisotropies in fold-thrust systems within the slumps match the various structural domains. We therefore suggest that magnetic fabrics and anisotropy variations in drill cores may reflect internal deformation within the slumps rather than different slumps. Obtaining magnetic fabrics from MTDs provides a viable way to infer the transport directions and internal deformation of MTDs and reconstruct the basin depocenter in ancient settings. The present results also have implications beyond the kinematics of MTDs, as their geometry resembles fold-thrust systems in other geological settings, scales, and tectonic environments.

  19. Designing a highly sensitive Eddy current sensor for evaluating damage on thermal barrier coating

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Min; Kim, Hak Joon; Song, Sung Jin; Seok, Chang Seong; Lee, Yeong Ze [Dept. of Mechanical Engineering, Sungkyunkwan University, Suwon (Korea, Republic of); Lee, Seul Gi [LG Electronics, Seoul (Korea, Republic of)

    2016-06-15

    A thermal barrier coating (TBC) has been widely applied to machine components working under high temperature as a thermal insulator owing to its critical financial and safety benefits to the industry. However, the nondestructive evaluation of TBC damage is not easy since sensing of the microscopic change that occurs on the TBC is required during an evaluation. We designed an eddy current probe for evaluating damage on a TBC based on the finite element method (FEM) and validated its performance through an experiment. An FEM analysis predicted the sensitivity of the probe, showing that impedance change increases as the TBC thermally degrades. In addition, the effect of the magnetic shield concentrating magnetic flux density was also observed. Finally, experimental validation showed good agreement with the simulation result.

  20. Fabrication of the GLAST Silicon Tracker Readout Electronics

    Energy Technology Data Exchange (ETDEWEB)

    Baldini, Luca; Brez, Alessandro; Himel, Thomas; Johnson, R.P.; Latronico, Luca; Minuti, Massimo; Nelson, David; Sadrozinski, H.F.-W.; Sgro, Carmelo; Spandre, Gloria; Sugizaki, Mutsumi; Tajima, Hiro; Cohen Tanugi, Johann; Young, Charles; Ziegler, Marcus; /Pisa U. /INFN, Pisa /SLAC /UC, Santa Cruz

    2006-03-03

    A unique electronics system has been built and tested for reading signals from the silicon-strip detectors of the Gamma-ray Large Area Space Telescope mission. The system amplifies and processes signals from 884,736 36-cm long silicon strips in a 4 x 4 array of tower modules. An aggressive mechanical design fits the readout electronics in narrow spaces between the tower modules, to minimize dead area. This design and the resulting departures from conventional electronics packaging led to several fabrication challenges and lessons learned. This paper describes the fabrication processes and how the problems peculiar to this design were overcome.

  1. Investigation of small scale sphere-pac fuel fabrication plant with external gelation process

    International Nuclear Information System (INIS)

    Maekawa, Kazuhiko; Yoshimura, Tadahiro; Kikuchi, Toshiaki; Hoshino, Yasushi; Munekata, Hideki; Shimizu, Makoto

    2005-02-01

    In feasibility studies on commercialized FBR cycle system, comprehensive system investigation and properties evaluation for candidate FBR cycle systems have been implemented through view point of safety, economics, environmental burden reduction, non-proliferation resistivity, etc. As part of these studies, an investigation of small scale sphere-pac fuel fabrication plant with external gelation process was conducted. Until last fiscal year, equipment layout in cells and overall layout design of the 200t-HM/y scale fuel fabrication plant were conducted as well as schematical design studies on main equipments in gelation and reagent recovery processes of the plant. System property data concerning economics and environmental burden reduction of fuel fabrication plant was also acquired. In this fiscal year, the processes from vibropacking to fuel assemblies storage were added to the investigation range, and a conceptual design of whole fuel fabrication plant was studied as well as deepening the design study on main equipments. The conceptual design study was mainly conducted for small 50t-HM/y scale plant and a revising investigation was done for 200t-HM/y scale plant. Taking the planed comparative evaluation with pellet fuel fabrication system into account, design of equipments which should be equivalent with pellet system, especially in post-vibropacking processes, were standardized in each system. Based on these design studies, system properties data concerning economics and environmental burden reduction of the plant was also acquired. In comparison with existing design, the cell height was lowered on condition that plug type pneumatic system was adopted and fuel fabrication building was downsized by applying rationalized layout design of pellet system to post-vibropacking processes. Reduction of reagent usage at gelation process and rationalization of sintering and O/M controlling processes etc., are foremost tasks. (author)

  2. Benchtop fabrication of PDMS microstructures by an unconventional photolithographic method

    International Nuclear Information System (INIS)

    Hwang, Chang Mo; Sim, Woo Young; Lee, Seung Hwan; Foudeh, Amir M; Bae, Hojae; Khademhosseini, Ali; Lee, Sang-Hoon

    2010-01-01

    Poly(dimethylsiloxane) (PDMS) microstructures have been widely used in bio-microelectromechanical systems (bio-MEMS) for various types of analytical, diagnostic and therapeutic applications. However, PDMS-based soft lithographic techniques still use conventional microfabrication processes to generate a master mold, which requires access to clean room facilities and costly equipment. With the increasing use of these systems in various fields, the development of benchtop systems for fabricating microdevices is emerging as an important challenge in their widespread use. Here we demonstrate a simple, low-cost and rapid method to fabricate PDMS microstructures by using micropatterned poly(ethylene glycol) diacrylate (PEGDA) master molds. In this method, PEGDA microstructures were patterned on a glass substrate by photolithography under ambient conditions and by using simple tools. The resulting PEGDA structures were subsequently used to generate PDMS microstructures by standard molding in a reproducible and repeatable manner. The thickness of the PEGDA microstructures was controllable from 15 to 300 μm by using commonly available spacer materials. We also demonstrate the use of this method to fabricate microfluidic channels capable of generating concentration gradients. In addition, we fabricated PEGDA microstructures by photolithography from the light generated from commonly available laminar cell culture hood. These data suggest that this approach could be beneficial for fabricating low-cost PDMS-based microdevices in resource limited settings.

  3. Paracoccidioidomicosis asociada a otras patologías respiratorias en un hospital de Corrientes, Argentina Association of paracoccidioidomycosis with different pulmonary pathologies in a hospital in Corrientes province, Argentina

    Directory of Open Access Journals (Sweden)

    A. M. Pato

    2007-09-01

    Full Text Available Se realizó la búsqueda sistemática de paracoccidioidomicosis (PCM en un conjunto de pacientes que fueron atendidos en un hospital de la ciudad de Corrientes dentro de un período de dos años. El criterio de inclusión fue: pacientes con tuberculosis (TBC, pacientes con diagnóstico presuntivo o confirmado de cáncer de pulmón (CA, pacientes con enfermedad pulmonar obstructiva crónica (EPOC y pacientes con imagen radiológica compatible con micosis pulmonar (IRXC. Se estudiaron 84 pacientes: 57 con TBC, 1 con CA, 5 con EPOC, 3 con TBC+CA, 4 con TBC+EPOC, 4 con EPOC+CA y 10 con IRXC. A todos se les realizó serología por inmunodifusión en gel de agar (IDGA y, en los casos en que se pudo obtener una muestra clínica, también se efectuaron estudios microbiológicos. Por IDGA se diagnosticaron 10 casos de PCM: 4 asociados a TBC, 1 a TBC+CA, 3 a EPOC y 2 a IRXC; 9 de ellos se corroboraron por el hallazgo del hongo. La búsqueda sistemática de PCM en habitantes del área endémica que presentan patología pulmonar favorecería el diagnóstico precoz y, por lo tanto, las posibilidades de un tratamiento eficaz.For 2 years, a systematic research of paracoccidioidomycosis (PCM had been conducted in a hospital in the city of Corrientes. The inclusion criterium used was: tuberculosis patients (TBC, presumptive or confirmed diagnosis of pulmonary cancer (CA, chronic obstructive pulmonary disease (COPD and/or X-ray images compatible with pulmonary mycosis (XRC. Eighty four patients were studied: 57 (TBC, 1 (CA, 5 (COPD, 3 (TBC+CA, 4 (TBC+COPD, 4 (COPD+CA and 10 (XRC. Serology tests by agar gel immunodiffusion (IDGA were performed on all patients, whereas microbiological studies were performed on those cases in which clinical samples could be obtained. Ten PCM were diagnosed by IDGA; 4 associated to TBC, 1 to TBC+CA, 3 to COPD and only 2 to XRC. PCM was mycologically proven in 9 of these cases. Systematic research of PCM would lead to an early

  4. Target fabrication using laser and spark erosion machining

    International Nuclear Information System (INIS)

    Clement, X.; Coudeville, A.; Eyharts, P.; Perrine, J.P.; Rouillard, R.

    1982-01-01

    Fabrication of laser fusion targets requires a number of special techniques. We have developed both laser and spark erosion machining to produce minute parts of complex targets. A high repetition rate YAG laser at double frequency is used to etch various materials. For example, marks or patterns are often necessary on structured or advanced targets. The laser is also used to thin down plastic coated stalks. A spark erosion system has proved to be a versatile tool and we describe current fabrication processes like cutting, drilling, and ultra precise machining. Spark erosion has interesting features for target fabrication: it is a highly controllable and reproducible technique as well as relatively inexpensive

  5. Analyzing polymeric matrix for fabrication of a biodegradable microneedle array to enhance transdermal delivery.

    Science.gov (United States)

    Hwa, Kuo-Yuan; Chang, Vincent H S; Cheng, Yao-Yi; Wang, Yue-Da; Jan, Pey-Shynan; Subramani, Boopathi; Wu, Min-Ju; Wang, Bo-Kai

    2017-09-19

    Traditional drug delivery systems, using invasive, transdermal, and oral routes, are limited by various factors, such as the digestive system environment, skin protection, and sensory nerve stimulation. To improve the drug delivery system, we fabricated a polysaccharide-based, dissolvable microneedle-based array, which combines the advantages of both invasive and transdermal delivery systems, and promises to be an innovative solution for minimally invasive drug delivery. In this study, we designed a reusable aluminum mold that greatly improved the efficiency and convenience of microneedle fabrication. Physical characterization of the polysaccharides, individual or mixed at different ratios, was performed to identify a suitable molecule to fabricate the dissolvable microneedle. We used a vacuum deposition-based micro-molding method at low temperature to fabricate the model. Using a series of checkpoints from material into product, a systematic feedback mechanism was built into the "all-in-one" fabrication step, which helped to improve production yields. The physical properties of the fabricated microneedle were assessed. The cytotoxicity analysis and animal testing of the microneedle demonstrated the safety and compatibility of the microneedle, and the successful penetration and effective release of a model protein.

  6. The fabrication process of ceramic grade UO2 powder via fluorid system AUC and the treatment on AUC precipitation filtrate

    International Nuclear Information System (INIS)

    Liu Jinhong; Xu Kui; Li Zhiwan; Yi Wei; Tang Yueming; Li Guangrong; Lei Maolin; Cui Chuanjiang

    2006-10-01

    It is described about the technology of fabricating AUC powder by Circum-fluence Precipitation Reactor with Gas (CPRG) from UF 6 hydrolyzed liquid, manufacturing nuclear pure ceramic grade UO 2 powder via fluorid system AUC process with fluidized bed method, recovering U(VI) with ion exchange resin, depositing fluorin in an outflow of effusion wastewater from the ion exchange using calces. The primary control parameters on the fabricating AUC powder is study, it is discussed to character difference of AUC powder between fluorid system and nitrate. Result show that the composing the manufacture AUC powder is invariable by CORG, and that the AUC quality is consistent, and that by decomposition and reduction of AUC and stabilization of UO 2 powder with fluidized bed, through optimum technological parameters, the excellent UO 2 powder is obtained on the quality. (authors)

  7. Hardware-Enabled Security Through On-Chip Reconfigurable Fabric

    Science.gov (United States)

    2016-02-05

    level language (SystemC) instead of in RTL such as Verilog and VHDL . To evaluate our approach, we implemented a set of monitors including soft...techniques can be implemented after chip fabrication. The study showed that such programmable architectures can indeed support a broad range of run- time...accelerators where security techniques can be implemented after chip fabrication. The study showed that such programmable architectures can indeed support a

  8. An automated flow injection system for metal determination by flame atomic absorption spectrometry involving on-line fabric disk sorptive extraction technique.

    Science.gov (United States)

    Anthemidis, A; Kazantzi, V; Samanidou, V; Kabir, A; Furton, K G

    2016-08-15

    A novel flow injection-fabric disk sorptive extraction (FI-FDSE) system was developed for automated determination of trace metals. The platform was based on a minicolumn packed with sol-gel coated fabric media in the form of disks, incorporated into an on-line solid-phase extraction system, coupled with flame atomic absorption spectrometry (FAAS). This configuration provides minor backpressure, resulting in high loading flow rates and shorter analytical cycles. The potentials of this technique were demonstrated for trace lead and cadmium determination in environmental water samples. The applicability of different sol-gel coated FPSE media was investigated. The on-line formed complex of metal with ammonium pyrrolidine dithiocarbamate (APDC) was retained onto the fabric surface and methyl isobutyl ketone (MIBK) was used to elute the analytes prior to atomization. For 90s preconcentration time, enrichment factors of 140 and 38 and detection limits (3σ) of 1.8 and 0.4μgL(-1) were achieved for lead and cadmium determination, respectively, with a sampling frequency of 30h(-1). The accuracy of the proposed method was estimated by analyzing standard reference materials and spiked water samples. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Fabrication process of expanded cooling jackets

    International Nuclear Information System (INIS)

    Weber, C.M.

    1980-01-01

    The present invention concerns the fabrication process of heat exchangers and in particular, the fabrication and assembly process of cooling jackets of the system driving the control rods used in nuclear reactors. The cooling jackets are assembled for cooling the stator of a tubular motor displacing the control rods. The fabrication and assembling of the cooling jacket is made up by the following operations: - a sleeve has an inner fluid inlet and outlet ways, - an external socket is fitted to the sleeve, - on the external socket a continuous welding is realized, which join the socket to the sleeve, and define a serie of parallel welded turns, - a pressure is established between the sleeve and the socket by a fluid through the outlet or inlet ways of the sleeve. When the other way is sealed up, the socket expands between the welded turns, and the fluid can pass through the jacket [fr

  10. Development and fabrication of the vacuum systems for an elliptically polarized undulator at Taiwan Photon Source

    Science.gov (United States)

    Chang, Chin-Chun; Chan, Che-Kai; Wu, Ling-Hui; Shueh, Chin; Shen, I.-Ching; Cheng, Chia-Mu; Yang, I.-Chen

    2017-05-01

    Three sets of a vacuum system were developed and fabricated for elliptically polarized undulators (EPU) of a 3-GeV synchrotron facility. These chambers were shaped with low roughness extrusion and oil-free machining; the design combines aluminium and stainless steel. The use of a bimetallic material to connect the EPU to the vacuum system achieves the vacuum sealing and to resolve the leakage issue due to bake process induced thermal expansion difference. The interior of the EPU chamber consists of a non-evaporable-getter strip pump in a narrow space to absorb photon-stimulated desorption and to provide a RF bridge design to decrease impedance effect in the two ends of EPU chamber. To fabricate these chambers and to evaluate the related performance, we performed a computer simulation to optimize the structure. During the machining and welding, the least deformation was achieved, less than 0.1 mm near 4 m. In the installation, the linear slider can provide a stable and precision moved along parallel the electron beam direction smoothly for the EPU chamber to decrease the twist issue during baking process. The pressure of the EPU chamber attained less than 2×10-8 Pa through baking. These vacuum systems of the EPU magnet have been installed in the electron storage ring of Taiwan Photon Source in 2015 May and have normally operated at 300 mA continuously since, and to keep beam life time achieved over than 12 h.

  11. Development and fabrication of the vacuum systems for an elliptically polarized undulator at Taiwan Photon Source

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Chin-Chun, E-mail: chinchun@nsrrc.org.tw; Chan, Che-Kai; Wu, Ling-Hui; Shueh, Chin; Shen, I.-Ching; Cheng, Chia-Mu; Yang, I.-Chen

    2017-05-01

    Three sets of a vacuum system were developed and fabricated for elliptically polarized undulators (EPU) of a 3-GeV synchrotron facility. These chambers were shaped with low roughness extrusion and oil-free machining; the design combines aluminium and stainless steel. The use of a bimetallic material to connect the EPU to the vacuum system achieves the vacuum sealing and to resolve the leakage issue due to bake process induced thermal expansion difference. The interior of the EPU chamber consists of a non-evaporable-getter strip pump in a narrow space to absorb photon-stimulated desorption and to provide a RF bridge design to decrease impedance effect in the two ends of EPU chamber. To fabricate these chambers and to evaluate the related performance, we performed a computer simulation to optimize the structure. During the machining and welding, the least deformation was achieved, less than 0.1 mm near 4 m. In the installation, the linear slider can provide a stable and precision moved along parallel the electron beam direction smoothly for the EPU chamber to decrease the twist issue during baking process. The pressure of the EPU chamber attained less than 2×10{sup −8} Pa through baking. These vacuum systems of the EPU magnet have been installed in the electron storage ring of Taiwan Photon Source in 2015 May and have normally operated at 300 mA continuously since, and to keep beam life time achieved over than 12 h.

  12. Sandia National Laboratories: Fabrication, Testing and Validation

    Science.gov (United States)

    digital and analog elements. * Cadence Process-Design Kit. Structured ASIC Sandia National Laboratories demonstrate complex multilevel devices such as micro-mass-analysis systems up to 25 microns thick and novel possible to fabricate a wide very large variety of useful devices. Micro-Mass-Analysis Systems Applications

  13. Self-assembled nanoformulation of methylprednisolone succinate with carboxylated block copolymer for local glucocorticoid therapy.

    Science.gov (United States)

    Kamalov, Marat I; Đặng, Trinh; Petrova, Natalia V; Laikov, Alexander V; Luong, Duong; Akhmadishina, Rezeda A; Lukashkin, Andrei N; Abdullin, Timur I

    2018-04-01

    A new self-assembled formulation of methylprednisolone succinate (MPS) based on a carboxylated trifunctional block copolymer of ethylene oxide and propylene oxide (TBC-COOH) was developed. TBC-COOH and MPS associated spontaneously at increased concentrations in aqueous solutions to form almost monodisperse mixed micelles (TBC-COOH/MPS) with a hydrodynamic diameter of 19.6 nm, zeta potential of -27.8 mV and optimal weight ratio ∼1:6.3. Conditions for the effective formation of TBC-COOH/MPS were elucidated by comparing copolymers and glucocorticoids with different structure. The micellar structure of TBC-COOH/MPS persisted upon dilution, temperature fluctuations and interaction with blood serum components. TBC-COOH increased antiradical activity of MPS and promoted its intrinsic cytotoxicity in vitro attributed to enhanced cellular availability of the mixed micelles. Intracellular transportation and hydrolysis of MPS were analyzed using optimized liquid chromatography tandem mass spectrometry with multiple reaction monitoring which showed increased level of both MPS and methylprednisolone in neuronal cells treated with the formulated glucocorticoid. Our results identify TBC-COOH/MPS as an advanced in situ prepared nanoformulation and encourage its further investigation for a potential local glucocorticoid therapy. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. DESIGN AND FABRICATION OF MICRONOZZLES

    Directory of Open Access Journals (Sweden)

    Kean How Cheah

    2011-05-01

    Full Text Available Normal 0 false false false EN-US ZH-CN X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:SimSun; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Micronozzle, a key component in micropropulsion system, has been designed and fabricated. Quasi 1D inviscid theory was used in designing a series of conical micronozzles of different expander half-angles (10°-50°. Aerospike micronozzle, a promising candidate to achieve high performance propulsion system, was designed with Angelino method (or Approximate method. Both micronozzles were fabricated using soft lithography, an inexpensive and relatively simple technique comparing to well-established deep reactive ion etching (DRIE technique, with polydimethylsiloxane (PDMS as structural material. Micronozzles with two different nozzle throat width, 53.5µm and 107µm, were fabricated for comparison. Microscopic inspections reveal 107µm is the more producible nozzle throat width with current equipments. The PDMS-based micronozzle can be used as cold gas microthruster system for micro- and nanosatellites.

  15. Microstructure, Tensile Adhesion Strength and Thermal Shock Resistance of TBCs with Different Flame-Sprayed Bond Coat Materials Onto BMI Polyimide Matrix Composite

    Science.gov (United States)

    Abedi, H. R.; Salehi, M.; Shafyei, A.

    2017-10-01

    In this study, thermal barrier coatings (TBCs) composed of different bond coats (Zn, Al, Cu-8Al and Cu-6Sn) with mullite top coats were flame-sprayed and air-plasma-sprayed, respectively, onto bismaleimide matrix composites. These polyimide matrix composites are of interest to replace PMR-15, due to concerns about the toxicity of the MDA monomer from which PMR-15 is made. The results showed that pores and cracks appeared at the bond coat/substrate interface for the Al-bonded TBC because of its high thermal conductivity and diffusivity resulting in transferring of high heat flux and temperature to the polymeric substrate during top coat deposition. The other TBC systems due to the lower conductivity and diffusivity of bonding layers could decrease the adverse thermal effect on the polymer substrate during top coat deposition and exhibited adhesive bond coat/substrate interfaces. The tensile adhesion test showed that the adhesion strength of the coatings to the substrate is inversely proportional to the level of residual stress in the coatings. However, the adhesion strength of Al bond-coated sample decreased strongly after mullite top coat deposition due to thermal damage at the bond coat/substrate interface. TBC system with the Cu-6Sn bond coat exhibited the best thermal shock resistance, while Al-bonded TBC showed the lowest. It was inferred that thermal mismatch stresses and oxidation of the bond coats were the main factors causing failure in the thermal shock test.

  16. Neuronal effects of 4-t-Butylcatechol: A model for catechol-containing antioxidants

    International Nuclear Information System (INIS)

    Lo, Y.-C.; Liu Yuxin; Lin, Y.-C.; Shih, Y.-T.; Liu, C.-M.; Burka, Leo T.

    2008-01-01

    Many herbal medicines and dietary supplements sold as aids to improve memory or treat neurodegenerative diseases or have other favorable effects on the CNS contain a catechol or similar 1,2-dihydroxy aromatic moiety in their structure. As an approach to isolate and examine the neuroprotective properties of catechols, a simple catechol 4-t-Butylcatechol (TBC) has been used as a model. In this study, we investigated the effects of TBC on lipopolysaccharide (LPS)-activated microglial-induced neurotoxicity by using the in vitro model of coculture murine microglial-like cell line HAPI with the neuronal-like human neuroblastoma cell line SH-SY5Y. We also examined the effects of TBC on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells. TBC at concentrations from 0.1-10 μM had no toxic effect on HAPI cells and SH-SY5Y cells, and it inhibited LPS (100 ng/ml)-induced increases of superoxide, intracellular ROS, gp91 Phox , iNOS and a decrease of HO-1 in HAPI cells. Under coculture condition, TBC significantly reduced LPS-activated microglia-induced dopaminergic SH-SY5Y cells death. Moreover, TBC (0.1-10 μM) inhibited 6-OHDA-induced increases of intracellular ROS, iNOS, nNOS, and a decrease of mitochondria membrane potential, and cell death in SH-SY5Y cells. However, the neurotoxic effects of TBC (100 μM) on SH-SY5Y cells were also observed including the decrease in mitochondria membrane potential and the increase in COX-2 expression and cell death. TBC-induced SH-SY5Y cell death was attenuated by pretreatment with NS-398, a selective COX-2 inhibitor. In conclusion, this study suggests that TBC might possess protective effects on inflammation- and oxidative stress-related neurodegenerative disorders. However, the high concentration of TBC might be toxic, at least in part, for increasing COX-2 expression

  17. Criticality in the fabrication of ion extraction system for SST-1 neutral beam injector

    International Nuclear Information System (INIS)

    Jana, M.R.; Mattoo, S.K.

    2008-01-01

    For the heating of plasma in steady-state superconducting tokamak (SST-1) (Y.C. Saxena, SST-1 Team, Present status of the SST-1 project, Nucl. Fusion 40 (2000) 1069-1082; D. Bora, SST-1 Team, Test results on systems developed for the SST-1 tokamak, Nucl. Fusion 43 (2003) 1748-1758), a neutral beam injector is provided to raise the ion temperature to ∼1 keV. This injector has a capability of injecting hydrogen beam with the power of 0.5 MW at 30 keV. For the upgrade of SST-1, power of 1.7 MW at 55 KeV is required. Further, beam power is to be provided for a pulse length of 1000S. We have designed a neutral beam injector (S.K. Mattoo, A.K. Chakraborty, U.K. Baruah, P.K. Jayakumar, M. Bandyopadhyay, N. Bisai, Ch. Chakrapani, M.R. Jana, R. Onali, V. Prahlad, P.J. Patel, G.B. Patel, B. Prajapati, N.V.M. Rao, S. Rambabu, C. Rotti, S.K. Sharma, S. Shah, V. Sharma, M.J. Singh, Engineering design of the steady-state neutral beam injector for SST-1, Fusion Eng. Des. 56 (2001) 685-691; A.K. Chakraborty, N. Bisai, M.R. Jana, P.K. Jayakumar, U.K. Baruah, P.J. Patel, K. Rajasekar, S.K. Mattoo, Neutral beam injector for steady-state superconducting tokamak, Fusion Technol. (1996) 657-660; P.K. Jayakumar, M.R. Jana, N. Bisai, M. Bajpai, N.P. Singh, U.K. Baruah, A.K. Chakraborty, M. Bandyopadhyay, C. Chrakrapani, D. Patel, G.B. Patel, P. Patel, V. Prahlad, N.V.M. Rao, C. Rotti, V. Sreedhar, S.K. Mattoo, Engineering issues of a 1000S neutral beam ion source, Fusion Technol. 1 (1998) 419-422) satisfying the requirements for both SST-1 and its upgrade. Since intense power is to be transported to SST-1 situated at a distance of several meters from the ion source, the optical quality of the beam becomes a primary concern. This in turn, is determined by the uniformity of the ion source plasma and the extractor geometry. To obtain the desired optical quality of the beam, stringent tolerances are to be met during the fabrication of ion extractor system. SST-1 neutral beam injector is

  18. Design and fabrication of a biomimetic gyroscope inspired by the fly’s haltere

    NARCIS (Netherlands)

    Droogendijk, H.; Brookhuis, Robert Anton; de Boer, Meint J.; Sanders, Remco G.P.; Krijnen, Gijsbertus J.M.

    2013-01-01

    We report on the design and fabrication of a MEMS-based gyroscopic system inspired by the fly’s haltere system. Two types of so-called biomimetic gyroscopes have been designed, fabricated and partially characterized. First measurements indicate excitable gyropscopes with natural frequencies in the

  19. Automated breeder fuel fabrication

    International Nuclear Information System (INIS)

    Goldmann, L.H.; Frederickson, J.R.

    1983-01-01

    The objective of the Secure Automated Fabrication (SAF) Project is to develop remotely operated equipment for the processing and manufacturing of breeder reactor fuel pins. The SAF line will be installed in the Fuels and Materials Examination Facility (FMEF). The FMEF is presently under construction at the Department of Energy's (DOE) Hanford site near Richland, Washington, and is operated by the Westinghouse Hanford Company (WHC). The fabrication and support systems of the SAF line are designed for computer-controlled operation from a centralized control room. Remote and automated fuel fabriction operations will result in: reduced radiation exposure to workers; enhanced safeguards; improved product quality; near real-time accountability, and increased productivity. The present schedule calls for installation of SAF line equipment in the FMEF beginning in 1984, with qualifying runs starting in 1986 and production commencing in 1987. 5 figures

  20. Food protein-based phytosterol nanoparticles: fabrication and characterization.

    Science.gov (United States)

    Cao, Wen-Jun; Ou, Shi-Yi; Lin, Wei-Feng; Tang, Chuan-He

    2016-09-14

    The development of food-grade (nano)particles as a delivery system for poorly water soluble bioactives has recently attracted increasing attention. This work is an attempt to fabricate food protein-based nanoparticles as delivery systems for improving the water dispersion and bioaccessibility of phytosterols (PS) by an emulsification-evaporation method. The fabricated PS nanoparticles were characterized in terms of particle size, encapsulation efficiency (EE%) and loading amount (LA), and ξ-potential. Among all the test proteins, including soy protein isolate (SPI), whey protein concentrate (WPC) and sodium caseinate (SC), SC was confirmed to be the most suitable protein for the PS nano-formulation. Besides the type of protein, the particle size, EE% and LA of PS in the nanoparticles varied with the applied protein concentration in the aqueous phase and organic volume fraction. The freeze-dried PS nanoparticles with SC exhibited good water re-dispersion behavior and low crystallinity of PS. The LA of PS in the nanoparticles decreased upon storage, especially at high temperatures (e.g., >25 °C). The PS in the fabricated nanoparticles exhibited much better bioaccessibility than free PS. The findings would be of relevance for the fabrication of food-grade colloidal phytosterols, with great potential to be applied in functional food formulations.

  1. Fabric based supercapacitor

    International Nuclear Information System (INIS)

    Yong, S; Tudor, M J; Beeby, S P; Owen, J R

    2013-01-01

    Flexible supercapacitors with electrodes coated on inexpensive fabrics by the dipping technique. This paper present details of the design, fabrication and characterisation of fabric supercapacitor. The sandwich structured supercapacitors can achieve specific capacitances of 11.1F/g, area capacitance 105 mF.cm −2 and maintain 95% of the initial capacitance after cycling the device for more than 15000 times

  2. Fabrication of quantum-dot devices in graphene

    Directory of Open Access Journals (Sweden)

    Satoshi Moriyama, Yoshifumi Morita, Eiichiro Watanabe, Daiju Tsuya, Shinya Uji, Maki Shimizu and Koji Ishibashi

    2010-01-01

    Full Text Available We describe our recent experimental results on the fabrication of quantum-dot devices in a graphene-based two-dimensional system. Graphene samples were prepared by micromechanical cleavage of graphite crystals on a SiO2/Si substrate. We performed micro-Raman spectroscopy measurements to determine the number of layers of graphene flakes during the device fabrication process. By applying a nanofabrication process to the identified graphene flakes, we prepared a double-quantum-dot device structure comprising two lateral quantum dots coupled in series. Measurements of low-temperature electrical transport show the device to be a series-coupled double-dot system with varied interdot tunnel coupling, the strength of which changes continuously and non-monotonically as a function of gate voltage.

  3. Application of new technology to the fabrication and installation of stainless steel pipework

    International Nuclear Information System (INIS)

    Halford, P.; Carrick, L.

    1989-01-01

    BNFL has been constructing new reprocessing plant on a continuous basis since the late seventies. Initially the productivity achieved when fabricating and welding stainless steel to nuclear standards was poor. In order to complete projects to programme and cost BNFL developed a Total Fabrication System that is now applied to all of their construction projects and has resulted in overall productivity increases by a factor of 2.4 with major quality and cost benefits. The development of the Total Fabrication System is described

  4. Design and fabrication of a low-cost Darrieus vertical-axis wind-turbine system, phase 2. Volume 3: Design, fabrication, and site drawing

    Science.gov (United States)

    1983-03-01

    The design, fabrication, and site drawings associated with fabrication, installation, and check out of 100 kW 17 meter Vertical Axis Wind Turbines (VAWTs) were reported. The turbines are Darrieus type VAWTs with rotors 17 meters in diameter and 25.15 meters in height. They can produce 100 kW of electric power at a cost of energy as low as 3 cents per kWh, in an 18 mph wind regime using 12% annualized costs. Four turbines are produced, three are installed and operable.

  5. High volume fabrication of laser targets using MEMS techniques

    International Nuclear Information System (INIS)

    Spindloe, C; Tomlinson, S; Green, J; Booth, N.; Tolley, M K; Arthur, G; Hall, F; Potter, R; Kar, S; Higginbotham, A

    2016-01-01

    The latest techniques for the fabrication of high power laser targets, using processes developed for the manufacture of Micro-Electro-Mechanical System (MEMS) devices are discussed. These laser targets are designed to meet the needs of the increased shot numbers that are available in the latest design of laser facilities. Traditionally laser targets have been fabricated using conventional machining or coarse etching processes and have been produced in quantities of 10s to low 100s. Such targets can be used for high complexity experiments such as Inertial Fusion Energy (IFE) studies and can have many complex components that need assembling and characterisation with high precision. Using the techniques that are common to MEMS devices and integrating these with an existing target fabrication capability we are able to manufacture and deliver targets to these systems. It also enables us to manufacture novel targets that have not been possible using other techniques. In addition, developments in the positioning systems that are required to deliver these targets to the laser focus are also required and a system to deliver the target to a focus of an F2 beam at 0.1Hz is discussed. (paper)

  6. Fabrication of Y-Ba-Cu-O (123) cuprate superconducting system and study of their electrical and structural properties

    International Nuclear Information System (INIS)

    Ahmed, F.; Hossain, M.K.; Sultana, H.R.; Abdul Hossain, M.; Khan, A.H.

    2005-08-01

    We know that in the YBa 2 Cu 3 O 6+x superconducting system transition temperature T c is highly dependent on the oxygen content in the compound. So, in order to fabricate superconducting YBa 2 Cu 3 O 6+x material under oxygen flow we have fabricated a tube furnace. Superconducting YBa 2 Cu 3 O 7-δ compounds were synthesized by the solid state reaction method. Different pressure for the pellet formation, different sintering and annealing conditions in air or in oxygen atmosphere were carried out to study the effect on the formation of superconducting phase. Samples were characterized by dc electrical resistance and X-ray diffraction. Superconducting Y 1-x Ca x Ba 2 Cu 3 O 7-δ compounds are now under investigation. (author)

  7. CMOS MEMS Fabrication Technologies and Devices

    Directory of Open Access Journals (Sweden)

    Hongwei Qu

    2016-01-01

    Full Text Available This paper reviews CMOS (complementary metal-oxide-semiconductor MEMS (micro-electro-mechanical systems fabrication technologies and enabled micro devices of various sensors and actuators. The technologies are classified based on the sequence of the fabrication of CMOS circuitry and MEMS elements, while SOI (silicon-on-insulator CMOS MEMS are introduced separately. Introduction of associated devices follows the description of the respective CMOS MEMS technologies. Due to the vast array of CMOS MEMS devices, this review focuses only on the most typical MEMS sensors and actuators including pressure sensors, inertial sensors, frequency reference devices and actuators utilizing different physics effects and the fabrication processes introduced. Moreover, the incorporation of MEMS and CMOS is limited to monolithic integration, meaning wafer-bonding-based stacking and other integration approaches, despite their advantages, are excluded from the discussion. Both competitive industrial products and state-of-the-art research results on CMOS MEMS are covered.

  8. Nuclear Fuel Test Rod Fabrication for Data Acquisition Test

    International Nuclear Information System (INIS)

    Joung, Chang-Young; Hong, Jin-Tae; Kim, Ka-Hye; Huh, Sung-Ho

    2014-01-01

    A nuclear fuel test rod must be fabricated with precise welding and assembly technologies, and confirmed for their soundness. Recently, we have developed various kinds of processing systems such as an orbital TIG welding system, a fiber laser welding system, an automated drilling system and a helium leak analyzer, which are able to fabricate the nuclear fuel test rods and rigs, and keep inspection systems to confirm the soundness of the nuclear fuel test rods and rids. The orbital TIG welding system can be used with two kinds of welding methods. One can perform the round welding for end-caps of a nuclear fuel test rod by an orbital head mounted in a low-pressure chamber. The other can do spot welding for a pin-hole of a nuclear fuel test rod in a high-pressure chamber to fill up helium gas of high pressure. The fiber laser welding system can weld cylindrical and 3 axis samples such as parts of a nuclear fuel test rod and instrumentation sensors which is moved by an index chuck and a 3 axis (X, Y, Z) servo stage controlled by the CNC program. To measure the real-time temperature change at the center of the nuclear fuel during the irradiation test, a thermocouple should be instrumented at that position. Therefore, a hole needs to be made at the center of fuel pellet to instrument the thermocouple. An automated drilling system can drill a fine hole into a fuel pellet without changing tools or breaking the work-piece. The helium leak analyzer (ASM-380 model of DEIXEN Co.) can check the leak of the nuclear fuel test rod filled with helium gas. This paper describes not only the assembly and fabrication methods used by the process systems, but also the results of the data acquisition test for the nuclear fuel test rod. A nuclear fuel test rod for the data acquisition test was fabricated using the welding and assembling echnologies acquired from previous tests

  9. Nuclear Fuel Test Rod Fabrication for Data Acquisition Test

    Energy Technology Data Exchange (ETDEWEB)

    Joung, Chang-Young; Hong, Jin-Tae; Kim, Ka-Hye; Huh, Sung-Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    A nuclear fuel test rod must be fabricated with precise welding and assembly technologies, and confirmed for their soundness. Recently, we have developed various kinds of processing systems such as an orbital TIG welding system, a fiber laser welding system, an automated drilling system and a helium leak analyzer, which are able to fabricate the nuclear fuel test rods and rigs, and keep inspection systems to confirm the soundness of the nuclear fuel test rods and rids. The orbital TIG welding system can be used with two kinds of welding methods. One can perform the round welding for end-caps of a nuclear fuel test rod by an orbital head mounted in a low-pressure chamber. The other can do spot welding for a pin-hole of a nuclear fuel test rod in a high-pressure chamber to fill up helium gas of high pressure. The fiber laser welding system can weld cylindrical and 3 axis samples such as parts of a nuclear fuel test rod and instrumentation sensors which is moved by an index chuck and a 3 axis (X, Y, Z) servo stage controlled by the CNC program. To measure the real-time temperature change at the center of the nuclear fuel during the irradiation test, a thermocouple should be instrumented at that position. Therefore, a hole needs to be made at the center of fuel pellet to instrument the thermocouple. An automated drilling system can drill a fine hole into a fuel pellet without changing tools or breaking the work-piece. The helium leak analyzer (ASM-380 model of DEIXEN Co.) can check the leak of the nuclear fuel test rod filled with helium gas. This paper describes not only the assembly and fabrication methods used by the process systems, but also the results of the data acquisition test for the nuclear fuel test rod. A nuclear fuel test rod for the data acquisition test was fabricated using the welding and assembling echnologies acquired from previous tests.

  10. Design and fabrication of a mechanical alloying system for preparing intermetallic, nanocrystalline, amorphous and quasicrystalline compounds

    International Nuclear Information System (INIS)

    Bonifacio M, J.; Iturbe G, J.L.; Castaneda J, G.

    2002-01-01

    In this work a grinding system was designed and fabricated which allowed to improve the operation conditions in time, frequency, temperature and selection of the grinding media and that allow the contamination decrease of the compounds. By means of this method of mechanical alloying new metallic compounds can be produced, starting from elemental powders, with fine and controlled microstructures. These compounds prepared by this method are going to be used as materials for the hydrogen storage. (Author)

  11. Electrical Properties of PPy-Coated Conductive Fabrics for Human Joint Motion Monitoring

    Directory of Open Access Journals (Sweden)

    Jiyong Hu

    2016-03-01

    Full Text Available Body motion signals indicate several pathological features of the human body, and a wearable human motion monitoring system can respond to human joint motion signal in real time, thereby enabling the prevention and treatment of some diseases. Because conductive fabrics can be well integrated with the garment, they are ideal as a sensing element of wearable human motion monitoring systems. This study prepared polypyrrole conductive fabric by in situ polymerization, and the anisotropic property of the conductive fabric resistance, resistance–strain relationship, and the relationship between resistance and the human knee and elbow movements are discussed preliminarily.

  12. Fabrication of cotton fabric with superhydrophobicity and flame retardancy.

    Science.gov (United States)

    Zhang, Ming; Wang, Chengyu

    2013-07-25

    A simple and facile method for fabricating the cotton fabric with superhydrophobicity and flame retardancy is described in the present work. The cotton fabric with the maximal WCA of 160° has been prepared by the covalent deposition of amino-silica nanospheres and the further graft with (heptadecafluoro-1,1,2,2-tetradecyl) trimethoxysilane. The geometric microstructure of silica spheres was measured by transmission electron microscopy (TEM). The cotton textiles before and after treatment were characterized by using scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). The wetting behavior of cotton samples was investigated by water contact angle measurement. Moreover, diverse performances of superhydrophobic cotton textiles have been evaluated as well. The results exhibited the outstanding superhydrophobicity, excellent waterproofing durability and flame retardancy of the cotton fabric after treatment, offering a good opportunity to accelerate the large-scale production of superhydrophobic textiles materials for new industrial applications. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Explicit Finite Element Modeling of Multilayer Composite Fabric for Gas Turbine Engine Containment Systems, Phase II. Part 3; Material Model Development and Simulation of Experiments

    Science.gov (United States)

    Simmons, J.; Erlich, D.; Shockey, D.

    2009-01-01

    A team consisting of Arizona State University, Honeywell Engines, Systems & Services, the National Aeronautics and Space Administration Glenn Research Center, and SRI International collaborated to develop computational models and verification testing for designing and evaluating turbine engine fan blade fabric containment structures. This research was conducted under the Federal Aviation Administration Airworthiness Assurance Center of Excellence and was sponsored by the Aircraft Catastrophic Failure Prevention Program. The research was directed toward improving the modeling of a turbine engine fabric containment structure for an engine blade-out containment demonstration test required for certification of aircraft engines. The research conducted in Phase II began a new level of capability to design and develop fan blade containment systems for turbine engines. Significant progress was made in three areas: (1) further development of the ballistic fabric model to increase confidence and robustness in the material models for the Kevlar(TradeName) and Zylon(TradeName) material models developed in Phase I, (2) the capability was improved for finite element modeling of multiple layers of fabric using multiple layers of shell elements, and (3) large-scale simulations were performed. This report concentrates on the material model development and simulations of the impact tests.

  14. Evaluation of miniature tension specimen fabrication techniques and performance

    International Nuclear Information System (INIS)

    Hamilton, M.L.; Blotter, M.A.; Edwards, D.J.

    1993-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed

  15. Evaluation of miniature tensile specimen fabrication techniques and performance

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, M.L. (Pacific Northwest Lab., Richland, WA (United States)); Blotter, M.A.; Edwards, D.J. (Missouri Univ., Rolla, MO (United States))

    1992-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical, milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed.

  16. Evaluation of miniature tensile specimen fabrication techniques and performance

    International Nuclear Information System (INIS)

    Hamilton, M.L.; Blotter, M.A.; Edwards, D.J.

    1992-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical, milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed

  17. Fabrication of fluidic devices with 30 nm nanochannels by direct imprinting

    DEFF Research Database (Denmark)

    Cuesta, Irene Fernandez; Palmarelli, Anna Laura; Liang, Xiaogan

    2011-01-01

    In this work, we propose an innovative approach to the fabrication of a complete micro/nano fluidic system, based on direct nanoimprint lithography. The fabricated device consists of nanochannels connected to U-shaped microchannels by triangular tapered inlets, and has four large reservoirs for l...

  18. Fabric Reconstruction Based on Sustainable Development: Take the Type of Fabric Recycling as an Example

    Directory of Open Access Journals (Sweden)

    Zhangting Guan

    2017-07-01

    Full Text Available Sustainable development is a very important concept of our time, it wants to do is to live in harmony with people, to protect the environment where our human survival. Fabric recycling refers to the use of a variety of traditional and high-tech means of the existing fabric fabric design and processing. So that the surface of a rich visual texture and tactile texture "through the fabric recycling approach. However, the fabric form and clothing design coordination between the clothing design is essential to the link! Garment fabric is not only the material basis of clothing modeling But also an important form of plastic arts. Fabric recycling art has gradually become a new breakthrough point of fashion design! And become an important means to increase the added value of clothing products. But at the same time fabric recycling also follow the concept of sustainable development. This paper analyzes the relationship between fabric reengineering and sustainable development. Combined with practice to explore the fabric processing technology and its creative ideas and some of its environmental performance.

  19. Alkali semi-metal films and method and apparatus for fabricating them

    Energy Technology Data Exchange (ETDEWEB)

    Bhandari, Harish B.; Nagarkar, Vivek V.; Ovechkina, Olena E.; Frisch, Henry J.; Attenkofer, Klaus; Smedley, John M.

    2018-03-13

    Methods and systems for fabricating a film, such as, for example, a photocathode, having a tailored band structure and thin-film components that can be tailored for specific applications, such as, for example photocathode having a high quantum efficiency, and simple components fabricated by those methods.

  20. A novel fabrication technique for free-hanging homogeneous polymeric cantilever waveguides

    DEFF Research Database (Denmark)

    Nordström, M.; Calleja, M.; Hübner, Jörg

    2008-01-01

    We present a novel bonding technique developed for the fabrication of a cantilever-based biosensing system with integrated optical read-out. The read-out mechanism is based on single-mode waveguides fabricated monolithically in SU-8. For optimal operation of the read-out mode, the cantilever...

  1. Design of conveyor utilization monitoring system: a case study of powder coating line in sheet metal fabrication

    Science.gov (United States)

    Prasetyo, Hoedi; Sugiarto, Yohanes; Nur Rosyidi, Cucuk

    2018-03-01

    Conveyor is a very useful equipment to replace manpower in transporting the goods. It highly influences the productivity, production capacity utilization and eventually the production cost. This paper proposes a system to monitor the utilization of conveyor at a low cost through a case study at powder coating process line in a sheet metal fabrication. Preliminary observation was conducted to identify the problems. The monitoring system was then built and executed. The system consists of two sub systems. First is sub system for collecting and transmitting the required data and the second is sub system for displaying the data. The system utilizes sensors, wireless data transfer and windows-based application. The test results showed that the whole system works properly. By this system, the productivity and status of the conveyor can be monitored in real time. This research enriches the development of conveyor monitoring system especially for implementation in small and medium enterprises.

  2. Optimum processing parameters for the fabrication of twill flax fabric-reinforced polypropylene (PP) composites

    Science.gov (United States)

    Zuhudi, Nurul Zuhairah Mahmud; Minhat, Mulia; Shamsuddin, Mohd Hafizi; Isa, Mohd Dali; Nur, Nurhayati Mohd

    2017-12-01

    In recent years, natural fabric thermoplastic composites such as flax have received much attention due to its attractive capabilities for structural applications. It is crucial to study the processing of flax fabric materials in order to achieve good quality and cost-effectiveness in fibre reinforced composites. Though flax fabric has been widely utilized for several years in composite applications due to its high strength and abundance in nature, much work has been concentrated on short flax fibre and very little work focused on using flax fabric. The effectiveness of the flax fabric is expected to give higher strength performance due to its structure but the processing needs to be optimised. Flax fabric composites were fabricated using compression moulding due to its simplicity, gives good surface finish and relatively low cost in terms of labour and production. Further, the impregnation of the polymer into the fabric is easier in this process. As the fabric weave structure contributes to the impregnation quality which leads to the overall performance, the processing parameters of consolidation i.e. pressure, time, and weight fraction of fabric were optimized using the Taguchi method. This optimization enhances the consolidation quality of the composite by improving the composite mechanical properties, three main tests were conducted i.e. tensile, flexural and impact test. It is observed that the processing parameter significantly affected the consolidation and quality of composite.

  3. FY 1989 report on the results of the development of the entrained bed coal gasification power plant. Part 3. Fabrication/installation of pilot plant (Fabrication/installation drawings and fabrication/installation pictures - 2/2); 1989 nendo seika hokokusho. Funryusho sekitan gaska hatsuden plant kaihatsu - Sono 3. Pilot plant seisaku suetsuke hen (Seisaku suetsukezu oyobi seisaku suetsuke shashin) (2/2)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-03-01

    For the purpose of establishing the technology of the integrated coal gasification combined cycle power generation, the fabrication, installation work, etc. were conducted of a 200t/d entrained bed coal gasification pilot plant, and fabrication/installation drawings and fabrication/installation pictures were summarized. In fabrication/installation drawings, drawings of the following were included: safety environmental equipment (total system diagram, layout scheme drawing, layout of electric room equipment, layout of control equipment room, etc.), total control system (structural drawing of the total control system, outline drawing of operation control panel, operator console of the integrated load pressure control system, operator console of the integrated sequential control system, central control panel, etc.), 66kV/6.9kV indoor switching station facilities (layout of equipment of indoor switching station facilities, outline drawing of the main transformer, outline drawing of cooler control panel of the main transformer, etc.), common facilities (total layout, diagram of the equipment cooling water pipe system, diagram of the fire-extinguishing water pipe system, etc.) In pictures of fabrication/installation, pictures of the following were included: gasifier equipment, gas refining facilities, gas turbine facilities, actual-pressure/actual-size combustor test equipment, safety environmental equipment, total control system, common facilities, etc. (NEDO)

  4. Paper-based membraneless hydrogen peroxide fuel cell prepared by micro-fabrication

    Science.gov (United States)

    Mousavi Ehteshami, Seyyed Mohsen; Asadnia, Mohsen; Tan, Swee Ngin; Chan, Siew Hwa

    2016-01-01

    A paper-based membraneless single-compartment hydrogen peroxide power source prepared by micro-electromechanical systems (MEMS) technology is reported. The cell utilizes hydrogen peroxide as both fuel and oxidant in a low volume cell fabricated on paper. The fabrication method used is a simple method where precise, small-sized patterns are produced which include the hydrophilic paper bounded by hydrophobic resin. Open circuit potentials of 0.61 V and 0.32 V are achieved for the cells fabricated with Prussian Blue as the cathode and aluminium/nickel as the anode materials, respectively. The power produced by the cells is 0.81 mW cm-2 at 0.26 V and 0.38 mW cm-2 at 0.14 V, respectively, even after the cell is bent or distorted. Such a fuel cell provides an easily fabricated, environmentally friendly, flexible and cost saving power source. The cell may be integrated within a self-sustained diagnostic system to provide the on-demand power for future bio-sensing applications.

  5. Fabrication and comparison of selective, transparent optics for concentrating solar systems

    Science.gov (United States)

    Taylor, Robert A.; Hewakuruppu, Yasitha; DeJarnette, Drew; Otanicar, Todd P.

    2015-09-01

    Concentrating optics enable solar thermal energy to be harvested at high temperature (solar) wavelengths, but highly reflective at long (thermal emission) wavelengths. If a solar system requires an analogous transparent, non-absorbing optic - i.e. a cover material which is highly transparent at short wavelengths, but highly reflective at long wavelengths - the technology is simply not available. Low-e glass technology represents a commercially viable option for this sector, but it has only been optimized for visible light transmission. Optically thin metal hole-arrays are another feasible solution, but are often difficult to fabricate. This study investigates combinations of thin film coatings of transparent conductive oxides and nanoparticles as a potential low cost solution for selective solar covers. This paper experimentally compares readily available materials deposited on various substrates and ranks them via an `efficiency factor for selectivity', which represents the efficiency of radiative exchange in a solar collector. Out of the materials studied, indium tin oxide and thin films of ZnS-Ag-ZnS represent the most feasible solutions for concentrated solar systems. Overall, this study provides an engineering design approach and guide for creating scalable, selective, transparent optics which could potentially be imbedded within conventional low-e glass production techniques.

  6. Methods for fabrication of flexible hybrid electronics

    Science.gov (United States)

    Street, Robert A.; Mei, Ping; Krusor, Brent; Ready, Steve E.; Zhang, Yong; Schwartz, David E.; Pierre, Adrien; Doris, Sean E.; Russo, Beverly; Kor, Siv; Veres, Janos

    2017-08-01

    Printed and flexible hybrid electronics is an emerging technology with potential applications in smart labels, wearable electronics, soft robotics, and prosthetics. Printed solution-based materials are compatible with plastic film substrates that are flexible, soft, and stretchable, thus enabling conformal integration with non-planar objects. In addition, manufacturing by printing is scalable to large areas and is amenable to low-cost sheet-fed and roll-to-roll processes. FHE includes display and sensory components to interface with users and environments. On the system level, devices also require electronic circuits for power, memory, signal conditioning, and communications. Those electronic components can be integrated onto a flexible substrate by either assembly or printing. PARC has developed systems and processes for realizing both approaches. This talk presents fabrication methods with an emphasis on techniques recently developed for the assembly of off-the-shelf chips. A few examples of systems fabricated with this approach are also described.

  7. A Fabric-Based Approach for Wearable Haptics

    Directory of Open Access Journals (Sweden)

    Matteo Bianchi

    2016-07-01

    Full Text Available In recent years, wearable haptic systems (WHS have gained increasing attention as a novel and exciting paradigm for human–robot interaction (HRI. These systems can be worn by users, carried around, and integrated in their everyday lives, thus enabling a more natural manner to deliver tactile cues. At the same time, the design of these types of devices presents new issues: the challenge is the correct identification of design guidelines, with the two-fold goal of minimizing system encumbrance and increasing the effectiveness and naturalness of stimulus delivery. Fabrics can represent a viable solution to tackle these issues. They are specifically thought “to be worn”, and could be the key ingredient to develop wearable haptic interfaces conceived for a more natural HRI. In this paper, the author will review some examples of fabric-based WHS that can be applied to different body locations, and elicit different haptic perceptions for different application fields. Perspective and future developments of this approach will be discussed.

  8. International light water nuclear fuel fabrication supply. Are fabrication services assured?

    International Nuclear Information System (INIS)

    Rothwell, Geoffrey

    2010-01-01

    This paper examines the cost structure of fabricating light water reactor (LWR) fuel with low-enriched uranium (LEU, with less than 5% enrichment). The LWR-LEU fuel industry is decades old, and (except for the high entry cost of designing and licensing a fuel fabrication facility and its fuel), labor and additional fabrication lines can be added at Nth-of-a-Kind cost to the maximum capacity allowed by a site license. The industry appears to be competitive: nuclear fuel fabrication capacity is assured with many competitors and reasonable prices. However, nuclear fuel assurance has become an important issue for nations now to considering new nuclear power plants. To provide this assurance many proposals equate 'nuclear fuel banks' (which would require fuel for specific reactors) with 'LEU banks' (where LEU could be blended into nuclear fuel with the proper enrichment) with local fuel fabrication. The policy issues (which are presented, but not answered in this paper) become (1) whether the construction of new nuclear fuel fabrication facilities in new nuclear power nations could lead to the proliferation of nuclear weapons, and (2) whether nuclear fuel quality can be guaranteed under current industry arrangements, given that fuel failure at one reactor can lead to forced shutdowns at many others. (author)

  9. Online Fabric Defect Inspection Using Smart Visual Sensors

    Directory of Open Access Journals (Sweden)

    Changqing Sun

    2013-04-01

    Full Text Available Fabric defect inspection is necessary and essential for quality control in the textile industry. Traditionally, fabric inspection to assure textile quality is done by humans, however, in the past years, researchers have paid attention to PC-based automatic inspection systems to improve the detection efficiency. This paper proposes a novel automatic inspection scheme for the warp knitting machine using smart visual sensors. The proposed system consists of multiple smart visual sensors and a controller. Each sensor can scan 800 mm width of web, and can work independently. The following are considered in dealing with broken-end defects caused by a single yarn: first, a smart visual sensor is composed of a powerful DSP processor and a 2-megapixel high definition image sensor. Second, a wavelet transform is used to decompose fabric images, and an improved direct thresholding method based on high frequency coefficients is proposed. Third, a proper template is chosen in a mathematical morphology filter to remove noise. Fourth, a defect detection algorithm is optimized to meet real-time demands. The proposed scheme has been running for six months on a warp knitting machine in a textile factory. The actual operation shows that the system is effective, and its detection rate reaches 98%.

  10. Quality in the fabrication process

    International Nuclear Information System (INIS)

    Romano, A.; Aguirre, F.

    2010-01-01

    Enusa commitment to quality in the manufacture process materializes in the application of the most advanced product quality control technologies such as not-destructive inspection techniques, like artificial vision, X-ray or UT inspection, or process parameter statistical control systems. Quality inspectors are trained and certified by the main National Quality Organizations and receive periodic training under a formal company training program that constantly updates their qualification. Fabrication quality control reliability is based on a strategy that prioritizes redundancy of critical inspection equipment's and inspection personnel knowledge polyvalence. Furthermore, improvement in fabrication quality is obtained by a systematic application of the six sigma methodology where added value is created in projects integrating crosscutting company knowledge, reinforcing the global company vision that the fuel business is based on quality. (Author)

  11. A novel fabrication technique for free-hanging homogeneous polymeric cantilever waveguides

    International Nuclear Information System (INIS)

    Nordström, Maria; Hübner, Jörg; Boisen, Anja; Calleja, Montserrat

    2008-01-01

    We present a novel bonding technique developed for the fabrication of a cantilever-based biosensing system with integrated optical read-out. The read-out mechanism is based on single-mode waveguides fabricated monolithically in SU-8. For optimal operation of the read-out mode, the cantilever waveguides should be homogenous and this bonding technique ensures free-hanging cantilevers that are surrounded by the same material for bottom and top claddings. The bonding step is necessary because SU-8 is a negative resist where free-hanging structures cannot be fabricated directly. This paper gives details on the processing aspects and the parameters of the fabrication steps

  12. Nozzle fabrication for Micro Propulsion of a Micro-Satellite

    NARCIS (Netherlands)

    Louwerse, M.C.; Jansen, Henricus V.; Groenendijk, M.N.W.; Elwenspoek, Michael Curt

    2008-01-01

    To enable formation flying of micro satellites, small sized propulsion systems are required. Our research focuses on the miniaturization of a feeding and thruster system by means of micro system technology (MST). Three fabrication methods have been investigated to make a conical converging-diverging

  13. Design and fabrication of a glovebox for the Plasma Hearth Process radioactive bench-scale system

    International Nuclear Information System (INIS)

    Wahlquist, D.R.

    1996-01-01

    This paper presents some of the design considerations and fabrication techniques for building a glovebox for the Plasma Hearth Process (PHP) radioactive bench-scale system. The PHP radioactive bench-scale system uses a plasma torch to process a variety of radioactive materials into a final vitrified waste form. The processed waste will contain plutonium and trace amounts of other radioactive materials. The glovebox used in this system is located directly below the plasma chamber and is called the Hearth Handling Enclosure (HHE). The HHE is designed to maintain a confinement boundary between the processed waste and the operator. Operations that take place inside the HHE include raising and lowering the hearth using a hydraulic lift table, transporting the hearth within the HHE using an overhead monorail and hoist system, sampling and disassembly of the processed waste and hearth, weighing the hearth, rebuilding a hearth, and sampling HEPA filters. The PHP radioactive bench-scale system is located at the TREAT facility at Argonne National Laboratory-West in Idaho Falls, Idaho

  14. CD36- and GPR120-mediated Ca²⁺ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice.

    Science.gov (United States)

    Ozdener, Mehmet Hakan; Subramaniam, Selvakumar; Sundaresan, Sinju; Sery, Omar; Hashimoto, Toshihiro; Asakawa, Yoshinori; Besnard, Philippe; Abumrad, Nada A; Khan, Naim Akhtar

    2014-04-01

    It is important to increase our understanding of gustatory detection of dietary fat and its contribution to fat preference. We studied the roles of the fat taste receptors CD36 and GPR120 and their interactions via Ca(2+) signaling in fungiform taste bud cells (TBC). We measured Ca(2+) signaling in human TBC, transfected with small interfering RNAs against messenger RNAs encoding CD36 and GPR120 (or control small interfering RNAs). We also studied Ca(2+) signaling in TBC from CD36(-/-) mice and from wild-type lean and obese mice. Additional studies were conducted with mouse enteroendocrine cell line STC-1 that express GPR120 and stably transfected with human CD36. We measured release of serotonin and glucagon-like peptide-1 from human and mice TBC in response to CD36 and GPR120 activation. High concentrations of linoleic acid induced Ca(2+) signaling via CD36 and GPR120 in human and mice TBC, as well as in STC-1 cells, and low concentrations induced Ca(2+) signaling via only CD36. Incubation of human and mice fungiform TBC with lineoleic acid down-regulated CD36 and up-regulated GPR120 in membrane lipid rafts. Obese mice had decreased spontaneous preference for fat. Fungiform TBC from obese mice had reduced Ca(2+) and serotonin responses, but increased release of glucagon-like peptide-1, along with reduced levels of CD36 and increased levels of GPR120 in lipid rafts. CD36 and GPR120 have nonoverlapping roles in TBC signaling during orogustatory perception of dietary lipids; these are differentially regulated by obesity. Copyright © 2014 AGA Institute. Published by Elsevier Inc. All rights reserved.

  15. A simple method of fabricating mask-free microfluidic devices for biological analysis.

    KAUST Repository

    Yi, Xin; Kodzius, Rimantas; Gong, Xiuqing; Xiao, Kang; Wen, Weijia

    2010-01-01

    We report a simple, low-cost, rapid, and mask-free method to fabricate two-dimensional (2D) and three-dimensional (3D) microfluidic chip for biological analysis researches. In this fabrication process, a laser system is used to cut through paper

  16. A review: fabrication of porous polyurethane scaffolds.

    Science.gov (United States)

    Janik, H; Marzec, M

    2015-03-01

    The aim of tissue engineering is the fabrication of three-dimensional scaffolds that can be used for the reconstruction and regeneration of damaged or deformed tissues and organs. A wide variety of techniques have been developed to create either fibrous or porous scaffolds from polymers, metals, composite materials and ceramics. However, the most promising materials are biodegradable polymers due to their comprehensive mechanical properties, ability to control the rate of degradation and similarities to natural tissue structures. Polyurethanes (PUs) are attractive candidates for scaffold fabrication, since they are biocompatible, and have excellent mechanical properties and mechanical flexibility. PU can be applied to various methods of porous scaffold fabrication, among which are solvent casting/particulate leaching, thermally induced phase separation, gas foaming, emulsion freeze-drying and melt moulding. Scaffold properties obtained by these techniques, including pore size, interconnectivity and total porosity, all depend on the thermal processing parameters, and the porogen agent and solvents used. In this review, various polyurethane systems for scaffolds are discussed, as well as methods of fabrication, including the latest developments, and their advantages and disadvantages. Copyright © 2014. Published by Elsevier B.V.

  17. Fabrication of micro metallic valve and pump

    Science.gov (United States)

    Yang, Ming; Kabasawa, Yasunari; Ito, Kuniyoshi

    2010-03-01

    Fabrication of micro devices by using micro metal forming was proposed by the authors. We developed a desktop servo-press machine with precise tooling system. Precise press forming processes including micro forging and micro joining has been carried out in a progressive die. In this study, micro metallic valve and pump were fabricated by using the precise press forming. The components are made of sheet metals, and assembled in to a unit in the progressive die. A micro check-valve with a diameter of 3mm and a length of 3.2mm was fabricated, and the property of flow resistance was evaluated. The results show that the check valve has high property of leakage proof. Since the valve is a unit parts with dimensions of several millimeters, it has advantage to be adapted to various pump design. Here, two kinds of micro pumps with the check-valves were fabricated. One is diaphragm pump actuated by vibration of the diaphragm, and another is tube-shaped pump actuated by resonation. The flow quantities of the pumps were evaluated and the results show that both of the pumps have high pumping performance.

  18. Micro and nano fabrication tools and processes

    CERN Document Server

    Gatzen, Hans H; Leuthold, Jürg

    2015-01-01

    For Microelectromechanical Systems (MEMS) and Nanoelectromechanical Systems (NEMS) production, each product requires a unique process technology. This book provides a comprehensive insight into the tools necessary for fabricating MEMS/NEMS and the process technologies applied. Besides, it describes enabling technologies which are necessary for a successful production, i.e., wafer planarization and bonding, as well as contamination control.

  19. Ocular Tuberculosis II: Diagnosis and Treatment

    Directory of Open Access Journals (Sweden)

    Sumru Önal

    2011-06-01

    Full Text Available Recent studies on the clinical importance of tuberculin skin tests (TST, interferon-gamma release assays (IGRAs, chest computed tomography (CT and polymerase chain reaction have provided a new approach to diagnosing ocular tuberculosis (TBC. However, both TST and IGRAs cannot distinguish between latent TBC infection and active disease. Another corroborative test in the diagnosis of intraocular TBC is the evaluation of the lungs by either chest radiography or CT. Direct evidence for the diagnosis can be obtained by examination of smears and staining for acid-fast organisms, cultures of intraocular tissue/fluid for Mycobacterium tuberculosis, and nucleic acid amplification analysis. In recent years, guidelines have been suggested for the diagnosis of intraocular TBC. The current treatment of intraocular TBC consists of use of four drugs (isoniazid, rifampicin, ethambutol and pyrazinamide taken for a long period of time (total 9-15 months. (Turk J Ophthalmol 2011; 41: 182-90

  20. Modern methods of material accounting for mixed-oxide fuel-fabrication facility

    International Nuclear Information System (INIS)

    Eggers, R.F.; Brouns, R.J.; Brite, D.W.; Pindak, J.L.

    1981-07-01

    The generic requirements loss detection, and response to alarms of a contemporary material control and accounting (MC and A) philosophy have been applied to a mixed-oxide fuel-fabrication plant to produce a detailed preliminary MC and A system design that is generally applicable to facilities of this type. This paper summarizes and discusses detailed results of the mixed-oxide fuel-fabrication plant study. Topics covered in this paper include: mixed-oxide fuel-fabrication process description, process disaggregation into MC and A system control units, quantitative results of analysis of control units for abrupt and recurring loss-detection capability, impact of short- and long-term holdup on loss-detection capability, response to alarms for abrupt loss, and response to alarms for recurring loss

  1. Fabrication and Characterisation of Low-noise Monolithic Mode-locked Lasers

    DEFF Research Database (Denmark)

    Larsson, David

    2007-01-01

    This thesis deals with the fabrication and characterisation of monolithic semiconductor mode-locked lasers for use in optical communication systems. Other foreseeable applications may be as sources in microwave photonics and optical sampling. The thesis also deals with the design and fabrication...... of intracavity monolithically integrated filters. The common dnominator among the diffrent parts of the thesis is how to achieve and measure the lowest possible noise. Achieving low noise has been pinpointed as one of the most important and difficult challenges for semiconductor mode-locked lasers. The main...... result of this thesis are a fabrication process of a monolithic and deeply etched distributed Bragg reflector and a characterisation system for measurement of quantum limitid timing noise at high repetition rates. The Bragg reflector is a key component in achieving transform limited pulses with low noise...

  2. Neural engineering from advanced biomaterials to 3D fabrication techniques

    CERN Document Server

    Kaplan, David

    2016-01-01

    This book covers the principles of advanced 3D fabrication techniques, stem cells and biomaterials for neural engineering. Renowned contributors cover topics such as neural tissue regeneration, peripheral and central nervous system repair, brain-machine interfaces and in vitro nervous system modeling. Within these areas, focus remains on exciting and emerging technologies such as highly developed neuroprostheses and the communication channels between the brain and prostheses, enabling technologies that are beneficial for development of therapeutic interventions, advanced fabrication techniques such as 3D bioprinting, photolithography, microfluidics, and subtractive fabrication, and the engineering of implantable neural grafts. There is a strong focus on stem cells and 3D bioprinting technologies throughout the book, including working with embryonic, fetal, neonatal, and adult stem cells and a variety of sophisticated 3D bioprinting methods for neural engineering applications. There is also a strong focus on b...

  3. A facile fabrication of multifunctional knit polyester fabric based on chitosan and polyaniline polymer nanocomposite

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Xiaoning [College of Textiles, Qingdao University, Qingdao, Shandong 266071 (China); Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Tian, Mingwei [College of Textiles, Qingdao University, Qingdao, Shandong 266071 (China); Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Collaborative Innovation Center for Marine Biomass Fibers, Materials and Textiles of Shandong Province, Qingdao University, Qingdao, Shandong 266071 (China); Qu, Lijun, E-mail: lijunqu@126.com [College of Textiles, Qingdao University, Qingdao, Shandong 266071 (China); Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Collaborative Innovation Center for Marine Biomass Fibers, Materials and Textiles of Shandong Province, Qingdao University, Qingdao, Shandong 266071 (China); Zhu, Shifeng [College of Textiles, Qingdao University, Qingdao, Shandong 266071 (China); Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Guo, Xiaoqing [College of Textiles, Qingdao University, Qingdao, Shandong 266071 (China); Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Collaborative Innovation Center for Marine Biomass Fibers, Materials and Textiles of Shandong Province, Qingdao University, Qingdao, Shandong 266071 (China); Han, Guangting [Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao, Shandong 266071 (China); Collaborative Innovation Center for Marine Biomass Fibers, Materials and Textiles of Shandong Province, Qingdao University, Qingdao, Shandong 266071 (China); and others

    2014-10-30

    Highlights: • Multifunctional knit polyester fabric was facile fabricated by the combination of pad-dry-cure process and in situ chemical polymerization route. • High electrical conductivity and efficient water-repellent properties were endowed to the polymer nanocomposite coated fabric. • The polymer nanocomposite coated fabric also performed efficient and durable photocatalytic activities under the illumination of ultraviolet light. - Abstract: Knit polyester fabric was successively modified and decorated with chitosan layer and polyaniline polymer nanocomposite layer in this paper. The fabric was firstly treated with chitosan to form a stable layer through the pad-dry-cure process, and then the polyaniline polymer nanocomposite layer was established on the outer layer by in situ chemical polymerization method using ammonium persulfate as oxidant and chlorhydric acid as dopant. The surface morphology of coated fabric was characterized by scanning electron microscopy (SEM), and the co-existence of chitosan layer and granular polyaniline polymer nanocomposite was confirmed and well dispersed on the fabric surface. The resultant fabric was endowed with remarkable electrical conductivity properties and efficient water-repellent capability, which also have been found stable after water laundering. In addition, the photocatalytic decomposition activity for reactive red dye was observed when the multifunctional knit polyester fabric was exposed to the illumination of ultraviolet lamp. These results indicated that chitosan and polyaniline polymer nanocomposite could form ideal multifunctional coatings on the surface of knit polyester fabric.

  4. A facile fabrication of multifunctional knit polyester fabric based on chitosan and polyaniline polymer nanocomposite

    International Nuclear Information System (INIS)

    Tang, Xiaoning; Tian, Mingwei; Qu, Lijun; Zhu, Shifeng; Guo, Xiaoqing; Han, Guangting

    2014-01-01

    Highlights: • Multifunctional knit polyester fabric was facile fabricated by the combination of pad-dry-cure process and in situ chemical polymerization route. • High electrical conductivity and efficient water-repellent properties were endowed to the polymer nanocomposite coated fabric. • The polymer nanocomposite coated fabric also performed efficient and durable photocatalytic activities under the illumination of ultraviolet light. - Abstract: Knit polyester fabric was successively modified and decorated with chitosan layer and polyaniline polymer nanocomposite layer in this paper. The fabric was firstly treated with chitosan to form a stable layer through the pad-dry-cure process, and then the polyaniline polymer nanocomposite layer was established on the outer layer by in situ chemical polymerization method using ammonium persulfate as oxidant and chlorhydric acid as dopant. The surface morphology of coated fabric was characterized by scanning electron microscopy (SEM), and the co-existence of chitosan layer and granular polyaniline polymer nanocomposite was confirmed and well dispersed on the fabric surface. The resultant fabric was endowed with remarkable electrical conductivity properties and efficient water-repellent capability, which also have been found stable after water laundering. In addition, the photocatalytic decomposition activity for reactive red dye was observed when the multifunctional knit polyester fabric was exposed to the illumination of ultraviolet lamp. These results indicated that chitosan and polyaniline polymer nanocomposite could form ideal multifunctional coatings on the surface of knit polyester fabric

  5. Current understanding of increased insulin sensitivity after exercise - emerging candidates

    DEFF Research Database (Denmark)

    Maarbjerg, Stine Just; Sylow, Lykke; Richter, Erik

    2011-01-01

    signaling component in the insulin signaling pathway such as aPKC, Rac1, TBC1D4 and TBC1D1 have been described. These are all affected by both insulin and exercise which means that they are likely converging points in promoting GLUT4 translocation and therefore possible candidates for regulating insulin...... sensitivity after exercise. Whereas TBC1D1 does not appear to regulate insulin sensitivity after exercise, correlative evidence in contrast suggests TBC1D4 to be a relevant candidate. Little is known about aPKC and Rac1 in relation to insulin sensitivity after exercise. Besides mechanisms involved...

  6. Bioresorbable nanofiber-based systems for wound healing and drug delivery: optimization of fabrication parameters.

    Science.gov (United States)

    Katti, Dhirendra S; Robinson, Kyle W; Ko, Frank K; Laurencin, Cato T

    2004-08-15

    Wound healing is a complex process that often requires treatment with antibiotics. This article reports the initial development of a biodegradable polymeric nanofiber-based antibiotic delivery system. The functions of such a system would be (a) to serve as a biodegradable gauze, and (b) to serve as an antibiotic delivery system. The polymer used in this study was poly(lactide-co-glycolide) (PLAGA), and nanofibers of PLAGA were fabricated with the use of the electrospinning process. The objective of this study was to determine the effect of fabrication parameters: orifice diameter (needle gauge), polymer solution concentration, and voltage per unit length, on the morphology and diameter of electrospun nanofibers. The needle gauges studied were 16 (1.19 mm), 18 (0.84 mm), and 20 (0.58 mm), and the range of polymer solution concentration studied was from 0.10 g/mL to 0.30 g/mL. The effect of voltage was determined by varying the voltage per unit electrospinning distance, and the range studied was from 0.375 kV/cm to 1.5 kV/cm. In addition, the mass per unit area of the electrospun nanofibers as a function of time was determined and the feasibility of antibiotic (cefazolin) loading into the nanofibers was also studied. The results indicate that the diameter of nanofibers decreased with an increase in needle gauge (decrease in orifice diameter), and increased with an increase in the concentration of the polymer solution. The voltage study demonstrated that the average diameter of the nanofibers decreased with an increase in voltage. However, the effect of voltage on fiber diameter was less pronounced as compared to polymer solution concentration. The results of the areal density study indicated that the mass per unit area of the electrospun nanofibers increased linearly with time. Feasibility of drug incorporation into the nanofibers was demonstrated with the use of cefazolin, a broad-spectrum antibiotic. Overall, these studies demonstrated that PLAGA nanofibers can be

  7. Flash μ-fluidics: a rapid prototyping method for fabricating microfluidic devices

    KAUST Repository

    Buttner, Ulrich

    2016-08-01

    Microfluidics has advanced in terms of design and structures; however, fabrication methods are time-consuming or expensive relative to facility costs and equipment needed. This work demonstrates a fast and economically viable 2D/3D maskless digital light-projection method based on a stereolithography process. Unlike other fabrication methods, one exposure step is used to form the whole device. Flash microfluidics is achieved by incorporating bonding and channel fabrication of complex structures in just 2.5 s to 4 s and by fabricating channel heights between 25 μm and 150 μm with photopolymer resin. The features of this fabrication technique, such as time and cost saving and easy fabrication, are used to build devices that are mostly needed in microfluidic/lab-on-chip systems. Due to the fast production method and low initial setup costs, the process could be used for point of care applications. © 2016 The Royal Society of Chemistry.

  8. Flash μ-fluidics: a rapid prototyping method for fabricating microfluidic devices

    KAUST Repository

    Buttner, Ulrich; Sivashankar, Shilpa; Agambayev, Sumeyra; Mashraei, Yousof; Salama, Khaled N.

    2016-01-01

    Microfluidics has advanced in terms of design and structures; however, fabrication methods are time-consuming or expensive relative to facility costs and equipment needed. This work demonstrates a fast and economically viable 2D/3D maskless digital light-projection method based on a stereolithography process. Unlike other fabrication methods, one exposure step is used to form the whole device. Flash microfluidics is achieved by incorporating bonding and channel fabrication of complex structures in just 2.5 s to 4 s and by fabricating channel heights between 25 μm and 150 μm with photopolymer resin. The features of this fabrication technique, such as time and cost saving and easy fabrication, are used to build devices that are mostly needed in microfluidic/lab-on-chip systems. Due to the fast production method and low initial setup costs, the process could be used for point of care applications. © 2016 The Royal Society of Chemistry.

  9. In vitro evaluation of marginal discrepancy of monolithic zirconia restorations fabricated with different CAD-CAM systems.

    Science.gov (United States)

    Hamza, Tamer A; Sherif, Rana M

    2017-06-01

    Dental laboratories use different computer-aided design and computer-aided manufacturing (CAD-CAM) systems to fabricate fixed prostheses; however, limited evidence is available concerning which system provides the best marginal discrepancy. The purpose of this in vitro study was to evaluate the marginal fit of 5 different monolithic zirconia restorations milled with different CAD-CAM systems. Thirty monolithic zirconia crowns were fabricated on a custom-designed stainless steel die and were divided into 5 groups according to the type of monolithic zirconia crown and the CAD-CAM system used: group TZ, milled with an MCXL milling machine; group CZ, translucent zirconia milled with a motion milling machine; group ZZ, zirconia milled with a dental milling unit; group PZ, translucent zirconia milled with a zirconia milling unit; and group BZ, solid zirconia milled using an S1 VHF milling machine. The marginal fit was measured with a binocular microscope at an original magnification of ×100. The results were tabulated and statistically analyzed with 1-way ANOVA and post hoc surface range test, and pairwise multiple comparisons were made using Bonferroni correction (α=.05). The type of CAD-CAM used affected the marginal fit of the monolithic restoration. The mean (±SD) highest marginal discrepancy was recorded in group TZI at 39.3 ±2.3 μm, while the least mean marginal discrepancy was recorded in group IZ (22.8 ±8.9 μm). The Bonferroni post hoc test showed that group TZI was significantly different from all other groups tested (Pmarginal discrepancies; however, the CAD-CAM system with the 5-axis milling unit produced the best marginal fit. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  10. Sintering furnace for remote fuel fabrication

    International Nuclear Information System (INIS)

    Bowen, W.W.

    1978-10-01

    Component testing and evaluation of a chemical vapor deposition Re/W muffle has been initiated. Hydrogen permeation testing and thermal cycling behavior will be evaluated. Fabrication of prototype 10-12 Kg furnace is scheduled for completion late in 1979, at which time testing of the system will be initiated

  11. Greenfield Alternative Study LEU-Mo Fuel Fabrication Facility

    Energy Technology Data Exchange (ETDEWEB)

    Washington Division of URS

    2008-07-01

    This report provides the initial “first look” of the design of the Greenfield Alternative of the Fuel Fabrication Capability (FFC); a facility to be built at a Greenfield DOE National Laboratory site. The FFC is designed to fabricate LEU-Mo monolithic fuel for the 5 US High Performance Research Reactors (HPRRs). This report provides a pre-conceptual design of the site, facility, process and equipment systems of the FFC; along with a preliminary hazards evaluation, risk assessment as well as the ROM cost and schedule estimate.

  12. Fabrication of SU-8 microstructures for analytical microfluidic applications

    OpenAIRE

    Tuomikoski, Santeri

    2007-01-01

    Miniaturization of analytical devices has been an ongoing trend to improve performance of analytical tools. These systems have been microfabricated originally of silicon and glass, but polymers have become increasingly popular as alternative materials. Polymers are mostly used because the material costs are lower and fabrication processes are easier. However, those facts depend heavily on the fabrication method and particular polymer. In this thesis the usability of epoxy-polymer SU-8 has bee...

  13. Design and fabrication of a micro PZT cantilever array actuator for applications in fluidic systems

    DEFF Research Database (Denmark)

    Kim, H.; In, C.; Yoon, Gil Ho

    2005-01-01

    In this article, a micro cantilever array actuated by PZT films is designed and fabricated for micro fluidic systems. The design features for maximizing tip deflections and minimizing fluid leakage are described. The governing equation of the composite PZT cantilever is derived and the actuating......, dielectric constant, and dielectric loss. Tip deflections of 12 mu m at 5 V are measured, which agreed well with the predicted value. The 18 mu l/s leakage rate of air was observed at a pressure difference of 1000 Pa. Micro cooler is introduced, and its possible application to micro compressor is discussed....

  14. Drip bloodstain appearance on inclined apparel fabrics: Effect of prior-laundering, fibre content and fabric structure.

    Science.gov (United States)

    de Castro, Therese C; Carr, Debra J; Taylor, Michael C; Kieser, Jules A; Duncan, Warwick

    2016-09-01

    The interaction of blood and fabrics is currently a 'hot topic', since the understanding and interpretation of these stains is still in its infancy. A recent simplified perpendicular impact experimental programme considering bloodstains generated on fabrics laid the foundations for understanding more complex scenarios. Blood rarely impacts apparel fabrics perpendicular; therefore a systematic study was conducted to characterise the appearance of drip stains on inclined fabrics. The final drip stain appearance for 45° and 15° impact angles on torso apparel fabrics (100% cotton plain woven, 100% polyester plain woven, a blend of polyester and cotton plain woven and 100% cotton single jersey knit) that had been laundered for six, 26 and 52 cycles prior to testing was investigated. The relationship between drop parameters (height and volume), angle and the stain characteristics (parent stain area, axis 1 and 2 and number of satellite stains) for each fabric was examined using analysis of variance. The appearance of the drip stains on these fabrics was distorted, in comparison to drip stains on hard-smooth surface. Examining the parent stain allowed for classification of stains occurring at an angle, however the same could not be said for the satellite stains produced. All of the dried stains visible on the surface of the fabric were larger than just after the impacting event, indicating within fabric spreading of blood due to capillary force (wicking). The cotton-containing fabrics spread the blood within the fabrics in all directions along the stain's circumference, while spreading within the polyester plain woven fabric occurred in only the weft (width of the fabric) and warp (length) directions. Laundering affected the formation of bloodstain on the blend plain woven fabric at both impact angles, although not all characteristics were significantly affected for the three impact conditions considered. The bloodstain characteristics varied due to the fibre content

  15. Flame retardant finishing of cotton fabric based on synergistic compounds containing boron and nitrogen.

    Science.gov (United States)

    Xie, Kongliang; Gao, Aiqin; Zhang, Yongsheng

    2013-10-15

    Boric acid and compound containing nitrogen, 2,4,6-tri[(2-hydroxy-3-trimethyl-ammonium)propyl]-1,3,5-triazine chloride (Tri-HTAC) were used to finish cotton fabric. The flame retardant properties of the finished cotton fabrics and the synergetic effects of boron and nitrogen elements were investigated and evaluated by limited oxygen index (LOI) method. The mechanism of cross-linking reaction among cotton fiber, Tri-HTAC, and boric acid was discussed by FTIR and element analysis. The thermal stability and surface morphology of the finished cotton fabrics were investigated by thermogravimetric analysis (TGA) and scanning electron microscope (SEM), respectively. The finishing system of the mixture containing boron and nitrogen showed excellent synergistic flame retardancy for cotton fabric. The cotton fabric finished with mixture system had excellent flame retardancy. The LOI value of the treated cotton fabric increased over 27.5. Tri-HTAC could form covalent bonds with cellulose fiber and boric acid. The flame retardant cotton fabric showed a slight decrease in tensile strength and whiteness. The surface morphology of flame retardant cotton fiber was smooth. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Fabrication and Characterization of Copper System Compound Semiconductor Solar Cells

    Directory of Open Access Journals (Sweden)

    Ryosuke Motoyoshi

    2010-01-01

    Full Text Available Copper system compound semiconductor solar cells were produced by a spin-coating method, and their cell performance and structures were investigated. Copper indium disulfide- (CIS- based solar cells with titanium dioxide (TiO2 were produced on F-doped SnO2 (FTO. A device based on an FTO/CIS/TiO2 structure provided better cell performance compared to that based on FTO/TiO2/CIS structure. Cupric oxide- (CuO- and cuprous oxide- (Cu2O- based solar cells with fullerene (C60 were also fabricated on FTO and indium tin oxide (ITO. The microstructure and cell performance of the CuO/C60 heterojunction and the Cu2O:C60 bulk heterojunction structure were investigated. The photovoltaic devices based on FTO/CuO/C60 and ITO/Cu2O:C60 structures provided short-circuit current density of 0.015 mAcm−2 and 0.11 mAcm−2, and open-circuit voltage of 0.045 V and 0.17 V under an Air Mass 1.5 illumination, respectively. The microstructures of the active layers were examined by X-ray diffraction and transmission electron microscopy.

  17. Influence of Fabric Parameters on Thermal Comfort Performance of Double Layer Knitted Interlock Fabrics

    Directory of Open Access Journals (Sweden)

    Afzal Ali

    2017-03-01

    Full Text Available The aim of this study was to analyse the effects of various fabric parameters on the thermal resistance, thermal conductivity, thermal transmittance, thermal absorptivity and thermal insulation of polyester/cotton double layer knitted interlock fabrics. It was found that by increasing fibre content with higher specific heat increases the thermal insulation while decreases the thermal transmittance and absorptivity of the fabric. It was concluded that double layer knitted fabrics developed with higher specific heat fibres, coarser yarn linear densities, higher knitting loop length and fabric thickness could be adequately used for winter clothing purposes.

  18. Remote fabrication of nuclear fuel: a secure automated fabrication overview

    International Nuclear Information System (INIS)

    Nyman, D.H.; Benson, E.M.; Yatabe, J.M.; Nagamoto, T.T.

    1981-01-01

    An automated line for the fabrication of breeder reactor fuel pins is being developed. The line will be installed in the Fuels and Materials Examination Facility (FMEF) presently under construction at the Hanford site near Richland, Washington. The application of automation and remote operations to fuel processing technology is needed to meet program requirements of reduced personnel exposure, enhanced safeguards, improved product quality, and increased productivity. Commercially available robots are being integrated into operations such as handling of radioactive material within a process operation. These and other automated equipment and chemistry analyses systems under development are described

  19. A facile method to fabricate superhydrophobic cotton fabrics

    Science.gov (United States)

    Zhang, Ming; Wang, Shuliang; Wang, Chengyu; Li, Jian

    2012-11-01

    A facile and novel method for fabricating superhydrophobic cotton fabrics is described in the present work. The superhydrophobic surface has been prepared by utilizing cationic poly (dimethyldiallylammonium chloride) and silica particles together with subsequent modification of (heptadecafluoro-1,1,2,2-tetradecyl) trimethoxysilane. The size distribution of silica particles was measured by Particle Size Analyzer. The cotton textiles before and after treatment were characterized by using scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). The wetting behavior of cotton samples was investigated by water contact angle measurement. Moreover, the superhydrophobic durability of coated cotton textiles has been evaluated by exposure, immersion and washing tests. The results show that the treated cotton fabrics exhibited excellent chemical stability and outstanding non-wettability with the WCA of 155 ± 2°, which offers an opportunity to accelerate the large-scale production of superhydrophobic textiles materials for new industrial applications.

  20. 3D ultrasound imaging for prosthesis fabrication and diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Morimoto, A.K.; Bow, W.J.; Strong, D.S. [and others

    1995-06-01

    The fabrication of a prosthetic socket for a below-the-knee amputee requires knowledge of the underlying bone structure in order to provide pressure relief for sensitive areas and support for load bearing areas. The goal is to enable the residual limb to bear pressure with greater ease and utility. Conventional methods of prosthesis fabrication are based on limited knowledge about the patient`s underlying bone structure. A 3D ultrasound imaging system was developed at Sandia National Laboratories. The imaging system provides information about the location of the bones in the residual limb along with the shape of the skin surface. Computer assisted design (CAD) software can use this data to design prosthetic sockets for amputees. Ultrasound was selected as the imaging modality. A computer model was developed to analyze the effect of the various scanning parameters and to assist in the design of the overall system. The 3D ultrasound imaging system combines off-the-shelf technology for image capturing, custom hardware, and control and image processing software to generate two types of image data -- volumetric and planar. Both volumetric and planar images reveal definition of skin and bone geometry with planar images providing details on muscle fascial planes, muscle/fat interfaces, and blood vessel definition. The 3D ultrasound imaging system was tested on 9 unilateral below-the- knee amputees. Image data was acquired from both the sound limb and the residual limb. The imaging system was operated in both volumetric and planar formats. An x-ray CT (Computed Tomography) scan was performed on each amputee for comparison. Results of the test indicate beneficial use of ultrasound to generate databases for fabrication of prostheses at a lower cost and with better initial fit as compared to manually fabricated prostheses.

  1. Transfer-free fabrication of graphene transistors

    OpenAIRE

    Wessely, P.J.; Wessely, F.; Birinci, E.; Schwalke, U.; Riedinger, B.

    2012-01-01

    The authors invented a method to fabricate graphene transistors on oxidized silicon wafers without the need to transfer graphene layers. To stimulate the growth of graphene layers on oxidized silicon, a catalyst system of nanometer thin aluminum/nickel double layer is used. This catalyst system is structured via liftoff before the wafer enters the catalytic chemical vapor deposition (CCVD) chamber. In the subsequent methane-based growth process, monolayer graphene field-effect transistors and...

  2. Robust, Self-Healing Superhydrophobic Fabrics Prepared by One-Step Coating of PDMS and Octadecylamine

    Science.gov (United States)

    Xue, Chao-Hua; Bai, Xue; Jia, Shun-Tian

    2016-01-01

    A robust, self-healing superhydrophobic poly(ethylene terephthalate) (PET) fabric was fabricated by a convenient solution-dipping method using an easily available material system consisting of polydimethylsiloxane and octadecylamine (ODA). The surface roughness was formed by self-roughening of ODA coating on PET fibers without any lithography steps or adding any nanomaterials. The fabric coating was durable to withstand 120 cycles of laundry and 5000 cycles of abrasion without apparently changing the superhydrophobicity. More interestingly, the fabric can restore its super liquid-repellent property by 72 h at room temperature even after 20000 cycles of abrasion. Meanwhile, after being damaged chemically, the fabric can restore its superhydrophobicity automatically in 12 h at room temperature or by a short-time heating treatment. We envision that this simple but effective coating system may lead to the development of robust protective clothing for various applications. PMID:27264995

  3. Fabric Reconstruction Based on Sustainable Development: Take the Type of Fabric Recycling as an Example

    OpenAIRE

    Zhangting Guan

    2017-01-01

    Sustainable development is a very important concept of our time, it wants to do is to live in harmony with people, to protect the environment where our human survival. Fabric recycling refers to the use of a variety of traditional and high-tech means of the existing fabric fabric design and processing. So that the surface of a rich visual texture and tactile texture "through the fabric recycling approach. However, the fabric form and clothing design coordination between the clothing design is...

  4. Asymmetric Superhydrophobic/Superhydrophilic Cotton Fabrics Designed by Spraying Polymer and Nanoparticles.

    Science.gov (United States)

    Sasaki, Kaichi; Tenjimbayashi, Mizuki; Manabe, Kengo; Shiratori, Seimei

    2016-01-13

    Inspired by the special wettability of certain natural life forms, such as the high water repellency of lotus leaves, many researchers have attempted to impart superhydrophobic properties to fabrics in academic and industrial contexts. Recently, a new switching system of wettability has inspired a strong demand for advanced coatings, even though their fabrication remains complex and costly. Here, cotton fabrics with asymmetric wettability (one face with natural superhydrophilicity and one face with superhydrophobicity) were fabricated by one-step spraying of a mixture of biocompatible commercial materials, hydrophobic SiO2 nanoparticles and ethyl-α-cyanoacrylate superglue. Our approach involves controlling the permeation of the fabric coatings by changing the distance between the fabric and the sprayer, to make one side superhydrophobic and the other side naturally superhydrophilic. As a result, the superhydrophobic side, with its high mechanical durability, exhibited a water contact angle of 154° and sliding angle of 16°, which meets the requirement for self-cleaning ability of surfaces. The opposite side exhibited high water absorption ability owing to the natural superhydrophilic property of the fabric. In addition, the designed cotton fabrics had blood absorption and clotting abilities on the superhydrophilic side, while the superhydrophobic side prevented water and blood permeation without losing the natural breathability of the cotton. These functions may be useful in the design of multifunctional fabrics for medical applications.

  5. The threshold bootstrap clustering: a new approach to find families or transmission clusters within molecular quasispecies.

    Directory of Open Access Journals (Sweden)

    Mattia C F Prosperi

    2010-10-01

    Full Text Available Phylogenetic methods produce hierarchies of molecular species, inferring knowledge about taxonomy and evolution. However, there is not yet a consensus methodology that provides a crisp partition of taxa, desirable when considering the problem of intra/inter-patient quasispecies classification or infection transmission event identification. We introduce the threshold bootstrap clustering (TBC, a new methodology for partitioning molecular sequences, that does not require a phylogenetic tree estimation.The TBC is an incremental partition algorithm, inspired by the stochastic Chinese restaurant process, and takes advantage of resampling techniques and models of sequence evolution. TBC uses as input a multiple alignment of molecular sequences and its output is a crisp partition of the taxa into an automatically determined number of clusters. By varying initial conditions, the algorithm can produce different partitions. We describe a procedure that selects a prime partition among a set of candidate ones and calculates a measure of cluster reliability. TBC was successfully tested for the identification of type-1 human immunodeficiency and hepatitis C virus subtypes, and compared with previously established methodologies. It was also evaluated in the problem of HIV-1 intra-patient quasispecies clustering, and for transmission cluster identification, using a set of sequences from patients with known transmission event histories.TBC has been shown to be effective for the subtyping of HIV and HCV, and for identifying intra-patient quasispecies. To some extent, the algorithm was able also to infer clusters corresponding to events of infection transmission. The computational complexity of TBC is quadratic in the number of taxa, lower than other established methods; in addition, TBC has been enhanced with a measure of cluster reliability. The TBC can be useful to characterise molecular quasipecies in a broad context.

  6. The threshold bootstrap clustering: a new approach to find families or transmission clusters within molecular quasispecies.

    Science.gov (United States)

    Prosperi, Mattia C F; De Luca, Andrea; Di Giambenedetto, Simona; Bracciale, Laura; Fabbiani, Massimiliano; Cauda, Roberto; Salemi, Marco

    2010-10-25

    Phylogenetic methods produce hierarchies of molecular species, inferring knowledge about taxonomy and evolution. However, there is not yet a consensus methodology that provides a crisp partition of taxa, desirable when considering the problem of intra/inter-patient quasispecies classification or infection transmission event identification. We introduce the threshold bootstrap clustering (TBC), a new methodology for partitioning molecular sequences, that does not require a phylogenetic tree estimation. The TBC is an incremental partition algorithm, inspired by the stochastic Chinese restaurant process, and takes advantage of resampling techniques and models of sequence evolution. TBC uses as input a multiple alignment of molecular sequences and its output is a crisp partition of the taxa into an automatically determined number of clusters. By varying initial conditions, the algorithm can produce different partitions. We describe a procedure that selects a prime partition among a set of candidate ones and calculates a measure of cluster reliability. TBC was successfully tested for the identification of type-1 human immunodeficiency and hepatitis C virus subtypes, and compared with previously established methodologies. It was also evaluated in the problem of HIV-1 intra-patient quasispecies clustering, and for transmission cluster identification, using a set of sequences from patients with known transmission event histories. TBC has been shown to be effective for the subtyping of HIV and HCV, and for identifying intra-patient quasispecies. To some extent, the algorithm was able also to infer clusters corresponding to events of infection transmission. The computational complexity of TBC is quadratic in the number of taxa, lower than other established methods; in addition, TBC has been enhanced with a measure of cluster reliability. The TBC can be useful to characterise molecular quasipecies in a broad context.

  7. Metallic Reactor Fuel Fabrication for SFR

    Energy Technology Data Exchange (ETDEWEB)

    Song, Hoon; Kim, Jong-Hwan; Ko, Young-Mo; Woo, Yoon-Myung; Kim, Ki-Hwan; Lee, Chan-Bock [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    The metal fuel for an SFR has such advantages such as simple fabrication procedures, good neutron economy, high thermal conductivity, excellent compatibility with a Na coolant, and inherent passive safety 1. U-Zr metal fuel for SFR is now being developed by KAERI as a national R and D program of Korea. The fabrication technology of metal fuel for SFR has been under development in Korea as a national nuclear R and D program since 2007. The fabrication process for SFR fuel is composed of (1) fuel slug casting, (2) loading and fabrication of the fuel rods, and (3) fabrication of the final fuel assemblies. Fuel slug casting is the dominant source of fuel losses and recycled streams in this fabrication process. Fabrication on the rod type metallic fuel was carried out for the purpose of establishing a practical fabrication method. Rod-type fuel slugs were fabricated by injection casting. Metallic fuel slugs fabricated showed a general appearance was smooth.

  8. One-pot fabrication and antimicrobial properties of novel PET nonwoven fabrics

    International Nuclear Information System (INIS)

    Lin Song; Wang Zheng; Qi Jiancheng; Wu Jinhui; Tian Tao; Hao Limei; Yang Jingquan; Hou Lili

    2011-01-01

    Recently, with the ever-growing demand for healthy living, more and more research is focused on materials capable of killing harmful microorganisms around the world. It is believed that designing such protective materials for hygienic and biomedical applications can benefit people in professional areas and daily life. Thus, in this paper, one novel kind of antibacterial poly(ethylene terephthalate) (PET) nonwoven fabrics was conveniently one-pot prepared, with the combined immobilization of two biological antimicrobial agents, i.e. ε-polylysine and natamycin, by using the soft methacrylate nonwoven fabrics adhesives. Then, the antimicrobial activities of the functional fabrics were investigated by using the standard shaking-flask method, showing excellent antibacterial efficiency (AE) against both Escherichia coli (8099) and Staphylococcus aureus (ATCC 6538) (AE > 99.99%) compared with untreated PET nonwoven fabrics. The anti-bioaerosol tests also showed similar trends. Meantime, scanning electron microscopy analysis indicated that the bacteria on the antibacterial PET appeared to be partly bacteriolyzed and showed much less viability than those on the pristine ones. Moreover, the long residual biocidal action of such modified PET fabrics was also evaluated, and the antibacterial activity of antibacterial fibers was unaffected by the 3 month artificially accelerated aging.

  9. One-pot fabrication and antimicrobial properties of novel PET nonwoven fabrics

    Energy Technology Data Exchange (ETDEWEB)

    Lin Song; Wang Zheng; Qi Jiancheng; Wu Jinhui; Tian Tao; Hao Limei; Yang Jingquan [Institute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161 (China); Hou Lili, E-mail: yjq789@sohu.com [National Bio-protection Engineering Center, Tianjin 300161 (China)

    2011-08-15

    Recently, with the ever-growing demand for healthy living, more and more research is focused on materials capable of killing harmful microorganisms around the world. It is believed that designing such protective materials for hygienic and biomedical applications can benefit people in professional areas and daily life. Thus, in this paper, one novel kind of antibacterial poly(ethylene terephthalate) (PET) nonwoven fabrics was conveniently one-pot prepared, with the combined immobilization of two biological antimicrobial agents, i.e. {epsilon}-polylysine and natamycin, by using the soft methacrylate nonwoven fabrics adhesives. Then, the antimicrobial activities of the functional fabrics were investigated by using the standard shaking-flask method, showing excellent antibacterial efficiency (AE) against both Escherichia coli (8099) and Staphylococcus aureus (ATCC 6538) (AE > 99.99%) compared with untreated PET nonwoven fabrics. The anti-bioaerosol tests also showed similar trends. Meantime, scanning electron microscopy analysis indicated that the bacteria on the antibacterial PET appeared to be partly bacteriolyzed and showed much less viability than those on the pristine ones. Moreover, the long residual biocidal action of such modified PET fabrics was also evaluated, and the antibacterial activity of antibacterial fibers was unaffected by the 3 month artificially accelerated aging.

  10. Fabrication of integrated metallic MEMS devices

    DEFF Research Database (Denmark)

    Yalcinkaya, Arda Deniz; Ravnkilde, Jan Tue; Hansen, Ole

    2002-01-01

    A simple and complementary metal oxide semiconductor (CMOS) compatible fabrication technique for microelectromechanical (MEMS) devices is presented. The fabrication technology makes use of electroplated metal layers. Among the fabricated devices, high quality factor microresonators are characteri......A simple and complementary metal oxide semiconductor (CMOS) compatible fabrication technique for microelectromechanical (MEMS) devices is presented. The fabrication technology makes use of electroplated metal layers. Among the fabricated devices, high quality factor microresonators...

  11. Optics fabrication technical challenges

    International Nuclear Information System (INIS)

    Chabassier, G.; Ferriou, N.; Lavastre, E.; Maunier, C.; Neauport, J.; Taroux, D.; Balla, D.; Fornerod, J.C.

    2004-01-01

    Before the production of all the LMJ (MEGAJOULE laser) optics, the CEA had to proceed with the fabrication of about 300 large optics for the LIL (laser integration line) laser. Thanks to a fruitful collaboration with high-tech optics companies in Europe, this challenge has been successfully hit. In order to achieve the very tight requirements for cleanliness, laser damage threshold and all the other high demanding fabrication specifications, it has been necessary to develop and to set completely new fabrication process going and to build special outsize fabrication equipment. Through a couple of examples, this paper gives an overview of the work which has been done and shows some of the results which have been obtained: continuous laser glass melting, fabrication of the laser slabs, rapid-growth KDP (potassium dihydrogen phosphate) technology, large diffractive transmission gratings engraving and characterization. (authors)

  12. Fabrication of a zirconia MEMS-based microthruster by gel casting on PDMS soft molds

    International Nuclear Information System (INIS)

    Cheah, K H; Khiew, P S; Chin, J K

    2012-01-01

    A zirconia microelectromechanical-system-based microthruster was fabricated through a newly developed fabrication route. Gel casting of homogenously dispersed zirconia suspension on polydimethylsiloxane soft mold was utilized to replicate the geometries of microthruster design onto a ceramic layer of about 1.2 mm thick. Lamination of the patterned ceramic layer to another flat ceramic layer and subsequent sintering produced the microthruster. Characterizations on the fabricated prototype showed good shape retention on the replicated geometries and good quality of lamination. Shrinkage of about 10–15% was noted after sintering. The current fabrication route is particularly promising for the development of high-performance micropropulsion systems which require their structural material to survive in an extreme environment which is corrosive, of high temperature and highly oxidative. (paper)

  13. FY 1990 report on the results of the development of the entrained bed coal gasification power plant. Part 3. Fabrication/installation of pilot plant (Fabrication/installation drawings and fabrication/installation pictures - 2/2); 1990 nendo seika hokokusho. Funryusho sekitan gaska hatsuden plant kaihatsu - Sono 3. Pilot plant seisaku suetsuke hen (Seisaku suetsukezu oyobi seisaku suetsuke shashin) (2/2)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    For the purpose of establishing the technology of the integrated coal gasification combined cycle power generation, the fabrication, installation work, etc. were conducted of a 200t/d entrained bed coal gasification pilot plant, and fabrication/installation drawings and fabrication/installation pictures were summarized. In fabrication/installation drawings, drawings of the following were included: actual-pressure/actual-size combustor test equipment (structural drawing of exhaust temperature reducing device, structural drawing of hot air device, system diagram of piping, etc.), safety environmental equipment (total system diagram, layout of electric room equipment, layout of control equipment room, etc.), total control system (structural drawing of the total control system, front view of auxiliary panel of safety environment equipment, etc.), 66kV/6.9kV indoor switching station facilities (layout of equipment of indoor switching station facilities, outline drawing of the main transformer, outline drawing of gas circuit breaker, etc.), common facilities (total layout, diagram of the nitrogen gas pipe system, system diagram of utility equipment, etc.) In pictures of fabrication/installation, pictures of the following were included: state of the construction work, gasifier equipment, gas refining facilities, gas turbine facilities, actual-pressure/actual-size combustor test equipment, safety environmental equipment, total control system, 66kV/6.9kV indoor switching station facilities, common facilities. (NEDO)

  14. Spectral Modeling of Residual Stress and Stored Elastic Strain Energy in Thermal Barrier Coatings

    Energy Technology Data Exchange (ETDEWEB)

    Donegan, Sean; Rolett, Anthony

    2013-12-31

    Solutions to the thermoelastic problem are important for characterizing the response under temperature change of refractory systems. This work extends a spectral fast Fourier transform (FFT) technique to analyze the thermoelastic behavior of thermal barrier coatings (TBCs), with the intent of probing the local origins of failure in TBCs. The thermoelastic FFT (teFFT) approach allows for the characterization of local thermal residual stress and strain fields, which constitute the origins of failure in TBC systems. A technique based on statistical extreme value theory known as peaks-over-threshold (POT) is developed to quantify the extreme values ("hot spots") of stored elastic strain energy (i.e., elastic energy density, or EED). The resolution dependence of the teFFT method is assessed through a sensitivity study of the extreme values in EED. The sensitivity study is performed both for the local (point-by-point) eld distributions as well as the grain scale eld distributions. A convergence behavior to a particular distribution shape is demonstrated for the local elds. The grain scale fields are shown to exhibit a possible convergence to a maximum level of EED. To apply the teFFT method to TBC systems, 3D synthetic microstructures are created to approximate actual TBC microstructures. The morphology of the grains in each constituent layer as well as the texture is controlled. A variety of TBC materials, including industry standard materials and potential future materials, are analyzed using the teFFT. The resulting hot spots are quantified using the POT approach. A correlation between hot spots in EED and interface rumpling between constituent layers is demonstrated, particularly for the interface between the bond coat (BC) and the thermally grown oxide (TGO) layer.

  15. Effects of dissolving microneedle fabrication parameters on the activity of encapsulated lysozyme.

    Science.gov (United States)

    Fakhraei Lahiji, Shayan; Jang, Yoojung; Ma, Yonghao; Dangol, Manita; Yang, Huisuk; Jang, Mingyu; Jung, Hyungil

    2018-05-30

    Dissolving microneedle (DMN) is referred to a microscale needle that encapsulates drug(s) within a biodegradable polymer matrix and delivers it into the skin in a minimally invasive manner. Although vast majority of studies have emphasized DMN as an efficient drug delivery system, the activity of DMN-encapsulated proteins or antigens can be significantly affected due to a series of thermal, physical and chemical stress factors during DMN fabrication process and storage period. The objective of this study is to evaluate the effects of DMN fabrication parameters including polymer type, polymer concentration, fabrication and storage temperature, and drying conditions on the activity of the encapsulated therapeutic proteins by employing lysozyme (LYS) as a model protein. Our results indicate that a combination of low temperature fabrication, mild drying condition, specific polymer concentration, and addition of protein stabilizer can maintain the activity of encapsulated LYS up to 99.8 ± 3.8%. Overall, findings of this study highlight the importance of optimizing DMN fabrication parameters and paves way for the commercialization of an efficient delivery system for therapeutics. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. On Stability of Exact Transparent Boundary Condition for the Parabolic Equation in Rectangular Computational Domain

    Science.gov (United States)

    Feshchenko, R. M.

    Recently a new exact transparent boundary condition (TBC) for the 3D parabolic wave equation (PWE) in rectangular computational domain was derived. However in the obtained form it does not appear to be unconditionally stable when used with, for instance, the Crank-Nicolson finite-difference scheme. In this paper two new formulations of the TBC for the 3D PWE in rectangular computational domain are reported, which are likely to be unconditionally stable. They are based on an unconditionally stable fully discrete TBC for the Crank-Nicolson scheme for the 2D PWE. These new forms of the TBC can be used for numerical solution of the 3D PWE when a higher precision is required.

  17. A Study on Mechanical behavior of Tensile Specimen Fabricated by Laser Cutting

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Y. G.; Kim, G. S.; Baik, S. J.; Baek, S. Y. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    The mechanical testing data are required for the assessment of dry storage of the spent nuclear fuel. Laser cutting system could be useful tools for material processing such as cutting in radioactive environment due to non-contact nature, ease in handling and the laser cutting process is most advantageous, offering the narrow kerf width and heat affected zone by using small beam spot diameter. The feasibility of the laser cutting system was demonstrated for the fabrication of various types of the unirradiated cladding with and without oxide layer on the specimens. In the present study, the dimensional measurement and tensile test were conducted to investigate the mechanical behavior of the axial tensile test specimens depending on the material processing methods in a hot cell at IMEF (Irradiated Materials Examination Facility) of KAERI. Laser cutting system was used to fabricate the tensile test specimens, and the mechanical behavior was investigated using the dimensional measurement and tensile test. It was shown that the laser beam machining could be a useful tool to fabricate the specimens and this technique will be developed for the fabrication of various types of irradiated specimens in a hotcell.

  18. A Study on Mechanical behavior of Tensile Specimen Fabricated by Laser Cutting

    International Nuclear Information System (INIS)

    Jin, Y. G.; Kim, G. S.; Baik, S. J.; Baek, S. Y.

    2016-01-01

    The mechanical testing data are required for the assessment of dry storage of the spent nuclear fuel. Laser cutting system could be useful tools for material processing such as cutting in radioactive environment due to non-contact nature, ease in handling and the laser cutting process is most advantageous, offering the narrow kerf width and heat affected zone by using small beam spot diameter. The feasibility of the laser cutting system was demonstrated for the fabrication of various types of the unirradiated cladding with and without oxide layer on the specimens. In the present study, the dimensional measurement and tensile test were conducted to investigate the mechanical behavior of the axial tensile test specimens depending on the material processing methods in a hot cell at IMEF (Irradiated Materials Examination Facility) of KAERI. Laser cutting system was used to fabricate the tensile test specimens, and the mechanical behavior was investigated using the dimensional measurement and tensile test. It was shown that the laser beam machining could be a useful tool to fabricate the specimens and this technique will be developed for the fabrication of various types of irradiated specimens in a hotcell

  19. Numerical research of heat and mass transfer at the ignition of systemfabric – combustible liquid – oxidant” by the local energy source

    Directory of Open Access Journals (Sweden)

    Glushkov Dmitrii O.

    2015-01-01

    Full Text Available A numerical research was executed for macroscopic regularities determination of heat and mass transfer processes under the conditions of phase transformation and chemical reaction at the ignition of vapour coming from fabrics impregnated by typical combustible liquid into oxidant area at the local power supply. Limit conditions of heterogeneous systemfabric – combustible liquid – oxidant” ignition at the heating of single metal particle was established. Dependences of ignition delay time on temperature and rates of local power source were obtained.

  20. Fabricating architectural volume

    DEFF Research Database (Denmark)

    Feringa, Jelle; Søndergaard, Asbjørn

    2015-01-01

    The 2011 edition of Fabricate inspired a number of collaborations, this article seeks to highlight three of these. There is a common thread amongst the projects presented: sharing the ambition to close the rift between design and fabrication while incorporating structural design aspects early on...

  1. Apparatus, system, and method for providing fabric-elastomer composites as pneumatic actuators

    Science.gov (United States)

    Martinez, Ramses V.; Whitesides, George M.

    2017-10-25

    Soft pneumatic actuators based on composites consisting of elastomers with embedded sheet or fiber structures (e.g., paper or fabric) that are flexible but not extensible are described. On pneumatic inflation, these actuators move anisotropically, based on the motions accessible by their composite structures. They are inexpensive, simple to fabricate, light in weight, and easy to actuate. This class of structure is versatile: the same principles of design lead to actuators that respond to pressurization with a wide range of motions (bending, extension, contraction, twisting, and others). Paper, when used to introduce anisotropy into elastomers, can be readily folded into three-dimensional structures following the principles of origami; these folded structures increase the stiffness and anisotropy of the elastomeric actuators, while keeping them light in weight.

  2. Design verification and fabrication of active control systems for the DAST ARW-2 high aspect ratio wing, part 1

    Science.gov (United States)

    Mcgehee, C. R.

    1986-01-01

    A study was conducted under Drones for Aerodynamic and Structural Testing (DAST) program to accomplish the final design and hardware fabrication for four active control systems compatible with and ready for installation in the NASA Aeroelastic Research Wing No. 2 (ARW-2) and Firebee II drone flight test vehicle. The wing structure was designed so that Active Control Systems (ACS) are required in the normal flight envelope by integrating control system design with aerodynamics and structure technologies. The DAST ARW-2 configuration uses flutter suppression, relaxed static stability, and gust and maneuver load alleviation ACS systems, and an automatic flight control system. Performance goals and criteria were applied to individual systems and the systems collectively to assure that vehicle stability margins, flutter margins, flying qualities and load reductions are achieved.

  3. Maintenance and fabrication of electronic equipment

    International Nuclear Information System (INIS)

    Chung, Chong Eun; Moon, Byung Soo; Hong, Suk Boong; Kim, Yong Keun; Kim, Jung Bok

    2001-12-01

    Providing technical support to the maintenance and repair problems of electronic instruments, we have assisted the research and development work, and made it done effectively in KAERI. In addition, we have improved the performance of the alarming system of the unit211 in PIEF and the lamp control module(IND100) in RWTF using PLCs. And also, electronic circuit modules for MAFF system which is an instrument for airborne monitoring in radiation area have been designed and fabricated

  4. Injection molded nanofluidic chips: Fabrication method and functional tests using single-molecule DNA experiments

    DEFF Research Database (Denmark)

    Utko, Pawel; Persson, Karl Fredrik; Kristensen, Anders

    2011-01-01

    We demonstrate that fabrication of nanofluidic systems can be greatly simplified by injection molding of polymers. We functionally test our devices by single-molecule DNA experiments in nanochannels.......We demonstrate that fabrication of nanofluidic systems can be greatly simplified by injection molding of polymers. We functionally test our devices by single-molecule DNA experiments in nanochannels....

  5. Fabrication of high aspect ratio nanocell lattices by ion beam irradiation

    International Nuclear Information System (INIS)

    Ishikawa, Osamu; Nitta, Noriko; Taniwaki, Masafumi

    2016-01-01

    Highlights: • Nanocell lattice with a high aspect ratio on InSb semiconductor surface was fabricated by ion beam irradiation. • The fabrication technique consisting of top-down and bottom-up processes was performed in FIB. • High aspect ratio of 2 was achieved in nanocell lattice with a 100 nm interval. • The intermediate-flux irradiation is favorable for fabrication of nanocell with a high aspect ratio. - Abstract: A high aspect ratio nanocell lattice was fabricated on the InSb semiconductor surface using the migration of point defects induced by ion beam irradiation. The fabrication technique consisting of the top-down (formation of voids and holes) and bottom-up (growth of voids and holes into nanocells) processes was performed using a focused ion beam (FIB) system. A cell aspect ratio of 2 (cell height/cell diameter) was achieved for the nanocell lattice with a 100 nm dot interval The intermediate-flux ion irradiation during the bottom-up process was found to be optimal for the fabrication of a high aspect ratio nanocell.

  6. An Improved Dispatching Method (a-HPDB for Automated Material Handling System with Active Rolling Belt for 450 mm Wafer Fabrication

    Directory of Open Access Journals (Sweden)

    Chia-Nan Wang

    2017-07-01

    Full Text Available The semiconductor industry is facing the transition from 300 mm to 450 mm wafer fabrication. Due to the increased size and weight, 450 mm wafers will pose unprecedented challenges on semiconductor wafer fabrication. To better handle and transport 450 mm wafers, an advanced Automated Material Handling System (AMHS is definitely required. Though conveyor-based AMHS is expected to be suitable for 450 mm wafer fabrication, still it faces two main problems, traffic-jam problem and lot-prioritization. To address the two problems, in this research we have proposed an improved dispatching method, termed Heuristic Preemptive Dispatching Method using Activated Roller Belt (a-HPDB. We have developed some effective rules for the a-HPDB based on Activated Roller Belt (ARB. In addition, we have conducted experiments to investigate its effectiveness. Compared with the HPDB and R-HPD, two dispatching rules proposed in previous studies, our experimental results showed the a-HPDB had a better performance in terms of average lot delivery time (ALDT. For hot lots and normal lots, the a-HPDB had advantages of 4.14% and 8.92% over the HPDB and advantages of 4.89% and 8.52% over R-HPD, respectively.

  7. New objective system of pilling evaluation for various types of fabrics

    Czech Academy of Sciences Publication Activity Database

    Techniková, L.; Tunák, M.; Janáček, Jiří

    2017-01-01

    Roč. 108, č. 1 (2017), s. 123-131 ISSN 0040-5000 Institutional support: RVO:67985823 Keywords : objective pilling evaluation * 3D fabric surface reconstruction * image analysis * pill characteristics * pilling grade Subject RIV: JS - Reliability ; Quality Management, Testing OBOR OECD: Textiles Impact factor: 1.007, year: 2016

  8. Fabrication of Durably Superhydrophobic Cotton Fabrics by Atmospheric Pressure Plasma Treatment with a Siloxane Precursor

    Directory of Open Access Journals (Sweden)

    Jing Yang

    2018-04-01

    Full Text Available The surface treatment of fabrics in an atmospheric environment may pave the way for commercially viable plasma modifications of fibrous matters. In this paper, we demonstrate a durably superhydrophobic cotton cellulose fabric prepared in a single-step graft polymerization of hexamethyldisiloxane (HMDSO by N2 and O2 atmospheric pressure plasma. We systematically investigated effects on contact angle (CA and surface morphology of the cotton fabric under three operational parameters: precursor value; ionization gas flow rate; and plasma cycle time. Surface morphology, element composition, chemical structure and hydrophobic properties of the treated fabric were characterized by scanning electron microscope (SEM, EDS, FTIR and CA on the fabrics. The results indicated that a layer of thin film and nano-particles were evenly deposited on the cotton fibers, and graft polymerization occurred between cellulose and HMDSO. The fabric treated by O2 plasma exhibited a higher CA of 162° than that treated by N2 plasma which was about 149°. Furthermore, the CA of treated fabrics decreased only 0°~10° after storing at the ambient conditions for four months, and treated fabrics could also endure the standard textile laundering procedure in AATCC 61-2006 with minimum change. Therefore, this single-step plasma treatment method is shown to be a novel and environment-friendly way to make durable and superhydrophobic cotton fabrics.

  9. Marginal accuracy of computer-aided design- and computer-aided manufacturing-fabricated full-arch zirconia restoration.

    Science.gov (United States)

    Juntavee, Niwut; Sirisathit, Issarawas

    2018-01-01

    This study evaluated marginal accuracy of full-arch zirconia restoration fabricated from two digital computer-aided design and computer-aided manufacturing (CAD-CAM) systems (Trios-3 and CS3500) in comparison to conventional cast metal restoration. A stainless steel model comprising two canine and two molar abutments was used as a master model for full-arch reconstruction. The canine and molar abutments were machined in a cylindrical shape with 5° taper and chamfer margin. The CAD-CAM systems based on the digital approach were used to construct the full-arch zirconia restoration. The conventional cast metal restoration was fabricated according to a conventional lost-wax technique using nickel-chromium alloys. Ten restorations were fabricated from each system. The marginal accuracy of each restoration was determined at four locations for each abutment. An analysis of variance (ANOVA) and Tukey's honest significant difference (HSD) multiple comparisons were used to determine statistically significant difference at 95% confidence interval. The mean values of marginal accuracy of restorations fabricated from conventional casting, Trios-3, and CS3500 were 48.59±4.16 μm, 53.50±5.66 μm, and 56.47±5.52 μm, respectively. ANOVA indicated significant difference in marginal fit of restorations among various systems. The marginal discrepancy of zirconia restoration fabricated from the CS3500 system demonstrated significantly larger gap than that fabricated from the 3Shape system ( p marginal gap than the conventional cast metal restoration ( p marginal fits than that from the CS3500, although, both were slightly less accurate than the conventional cast restoration. However, the marginal discrepancies of restoration produced by both CAD-CAM systems were within the clinically acceptable range and satisfactorily precise to be suggested for construction full-arch zirconia restoration.

  10. Tests of Flammability of Cotton Fabrics and Expected Skin Burns in Microgravity

    Science.gov (United States)

    Cavanagh, Jane M.; Torvi, David A.; Gabriel, Kamiel S.; Ruff, Gary A.

    2004-01-01

    During a shuttle launch and other portions of space flight, astronauts wear specialized flame resistant clothing. However during most of their missions on board the Space Shuttle or International Space Station, astronauts wear ordinary clothing, such as cotton shirts and pants. As the behaviour of flames is considerably different in microgravity than under earth s gravity, fabrics are expected to burn in a different fashion in microgravity than when tested on earth. There is interest in determining how this change in burning behaviour may affect times to second and third degree burn of human skin, and how the results of standard fabric flammability tests conducted under earth s gravity correlate with the expected fire behaviour of textiles in microgravity. A new experimental apparatus was developed to fit into the Spacecraft Fire Safety Facility (SFSF), which is used on NASA s KC-135 low gravity aircraft. The new apparatus was designed to be similar to the apparatus used in standard vertical flammability tests of fabrics. However, rather than using a laboratory burner, the apparatus uses a hot wire system to ignite 200 mm high by 80 mm wide fabric specimens. Fabric temperatures are measured using thermocouples and/or an infrared imaging system, while flame spread rates are measured using real time observations or video. Heat flux gauges are placed between 7 and 13 mm away from the fabric specimen, so that heat fluxes from the burning fabric to the skin can be estimated, along with predicted times required to produce skin burns.

  11. Facile fabrication of highly controllable gating systems based on the combination of inverse opal structure and dynamic covalent chemistry.

    Science.gov (United States)

    Wang, Chen; Yang, Haowei; Tian, Li; Wang, Shiqiang; Gao, Ning; Zhang, Wanlin; Wang, Peng; Yin, Xianpeng; Li, Guangtao

    2017-06-01

    A three-dimensional (3D) inverse opal with periodic and porous structures has shown great potential for applications not only in optics and optoelectronics, but also in functional membranes. In this work, the benzaldehyde group was initially introduced into a 3D nanoporous inverse opal, serving as a platform for fabricating functional membranes. By employing the dynamic covalent approach, a highly controllable gating system was facilely fabricated to achieve modulable and reversible transport features. It was found that the physical/chemical properties and pore size of the gating system could easily be regulated through post-modification with amines. As a demonstration, the gated nanopores were modified with three kinds of amines to control the wettability, surface charge and nanopore size which in turn was exploited to achieve selective mass transport, including hydrophobic molecules, cations and anions, and the transport with respect to the physical steric hindrance. In particular, the gating system showed extraordinary reversibility and could recover to its pristine state by simply changing pH values. Due to the unlimited variety provided by the Schiff base reaction, the inverse opal described here exhibits a significant extendibility and could be easily post-modified with stimuli-responsive molecules for special purposes. Furthermore, this work can be extended to employ other dynamic covalent routes, for example Diels-Alder, ester exchange and disulfide exchange-based routes.

  12. Investigation on the Interface Characteristics of the Thermal Barrier Coating System through Flat Cylindrical Indenters

    Directory of Open Access Journals (Sweden)

    Shifeng Wen

    2014-01-01

    Full Text Available Thermal barrier coating (TBC systems are highly advanced material systems and usually applied to insulate components from large and prolonged heat loads by utilizing thermally insulating materials. In this study, the characteristics of the interface of thermal barrier coating systems have been simulated by the finite-element method (FEM. The emphasis was put on the stress distribution at the interface which is beneath the indenter. The effect of the interface roughness, the thermally grown oxide (TGO layer's thickness, and the modulus ratio (η of the thin film with the substrate has been considered. Finite-element results showed that the influences of the interface roughness and the TGO layer's thickness on stress distribution were important. At the same time, the residual stress distribution has been investigated in detail.

  13. Efficient fabrication of micro- and nano-systems

    DEFF Research Database (Denmark)

    Birkelund, Karen; Hanberg, Peter Jesper; Jørgensen, Anders Michael

    2014-01-01

    There is an increasing demand for a more sustainable society where unnecessary use of the Worlds energy resources is avoided. Micro- and nano-fabricated sensors and actuators are in that sense desirable in many applications for power saving purposes, minimization of chemical consumption, rapid...... analyzing of e.g.waste water before it is lead out in our lakes and oceans or as sensors notifying when maintenance i srequired in due time before breakdown.More and more of these sensors are also made self-sufficient of power by harvesting the energy from e.g.the sun, thermal excess energy, environmental...... as minimizing the consumption of materials, etchants and process time. Danchip excels in optimizing micro- and nanofabrication in order to simplify processes, minimize cost and at the same time maximize yield. Danchips team of process generalists is ready to guide you through your design and planning phase...

  14. Application of waterproof breathable fabric in thermal protective clothing exposed to hot water and steam

    Science.gov (United States)

    Su, Y.; Li, R.; Song, G.; Li, J.

    2017-10-01

    A hot water and steam tester was used to examine thermal protective performance of waterproof and breathable fabric against hot water and steam hazards. Time to cause skin burn and thermal energy absorbed by skin during exposure and cooling phases was employed to characterize the effect of configuration, placing order and properties of waterproof and breathable fabric on the thermal protective performance. The difference of thermal protective performance due to hot water and steam hazards was discussed. The result showed that the configuration of waterproof and breathable fabric presented a significant effect on the thermal protective performance of single- and double-layer fabric system, while the difference between different configurations in steam hazard was greater than that in hot water hazard. The waterproof and breathable fabric as outer layer provided better protection than that as inner layer. Increasing thickness and moisture regain improved the thermal protective performance of fabric system. Additionally, the thermal energy absorbed by skin during the cooling phase was affected by configuration, thickness and moisture regain of fabric. The findings will provide technical data to improve performance of thermal protective clothing in hot water and steam hazards.

  15. The Study of Fabric Performance for Car Seats

    Directory of Open Access Journals (Sweden)

    Antonin Havelka

    2017-09-01

    Full Text Available This paper deals with the investigation of the performance of car seat fabrics in terms of physiological comfort of sitting, specifi cally their water vapour resistance and air permeability. The current work presents an alternative approach to increasing the effectiveness of car seat fabrics through a combination of newly designed middle layer with forced convection achieved by a supplementary suction ventilation device. The supplementary device was designed to measure water vapour permeability by means of the sweating guarded hot plate (SGHP system. It consists of two parts: a frame to grip a tested sample for measurements within the SGHP system and two suction ventilators which are arranged at one end of the mentioned frame in order to provide suction into the tested fabric plane during the SGHP test. The results of this investigation show that water vapour transport is increased by approximately 20% compared to the standard way of measurement by means of SGHP because of forced air flow in the plane of ribbed – channelled structure of the car seat middle layer. The findings of this study have a number of important implications for future practice. The combination of a car seat cover with channelled structure and forced air fl ow improves physiological comfort of sitting which is a key issue for both drivers and manufacturers. The suggested device for forced air flow convection in the plane of a car seat fabric has not yet been part of an actual car seat, however it is possible to use its principles in a smart car seat prototype.

  16. Accuracy of CAD-CAM-fabricated removable partial dentures.

    Science.gov (United States)

    Arnold, Christin; Hey, Jeremias; Schweyen, Ramona; Setz, Jürgen M

    2018-04-01

    The conventional fabrication of removable partial dentures (RPDs) is a complex, error-prone, time-consuming, and expensive process. The use of computer-aided design and computer-aided manufacturing (CAD-CAM) techniques, especially rapid prototyping, promises a more effective method for fabricating RPD frameworks. The purpose of this in vitro study was to evaluate the fit of RPD clasps fabricated by means of 4 different CAD-CAM-systems and to compare those fittings with that of the conventional lost-wax casting technique (LWT). A master model of a partially edentulous maxilla with the canines and second molars as the remaining teeth was fabricated. After the model was optically scanned, we designed a quadrangularly supported RPD with 4 clasps and a palatal strap major connector. A standard tessellation language data set was used to fabricate 12 identical RPDs by using 4 different CAD-CAM techniques: indirect rapid prototyping (wax inject printing combined with LWT), direct rapid prototyping (selective laser melting), indirect milling (wax milling with LWT), and direct milling (resin milling [polyetheretherketone]). Three conventionally cast RPDs (LWT) served as the control group. The fit accuracy of the clasps (n=12 for each group) was determined in both the horizontal and vertical dimensions by using light microscopy. Indirectly milled RPDs (117 ±34 μm horizontal and 45 ±21 μm vertical) and directly milled RPDs (43 ±23 μm horizontal, and 38 ±21 μm vertical) showed significantly better (P<.05) fit than did conventionally fabricated LWT RPDs (133 ±59 μm horizontal; 73 ±25 μm vertical). The worst fit was found for RPDs fabricated using indirect rapid prototyping (323 ±188 μm horizontal and 112 ±60 μm vertical) or direct rapid prototyping (365 ±205 μm horizontal and 363 ±133 μm vertical), which were unstable on the master model, making them unsuitable for clinical use. Most RPDs exhibited smaller vertical measuring distances. Compared with the LWT

  17. Flexible manufacturing systems and their relevance in nuclear fuel fabrication in India

    International Nuclear Information System (INIS)

    Ramakumar, M.S.

    1989-01-01

    Fabrication of nuclear reactor fuel bundle involves several materials and a number of complicated technologies and the process of manufacture has to conform to stringent standards. The Indian Nuclear Programme relies heavily on indigeneous capability of manufacture of nuclear fuels as well as automation of the related facilities. Automation of the existing nuclear facilities is a challenge in view of the characteristic plant environments and process demands as well as the various mechanical and metallurgical steps involved. This paper discusses their requirements and the measures initiated for achieving a high order of automation in Indian nuclear facilities. As a first step, specific automation steps are being incorporated in the existing plants. Such interface automation will enhance productivity and avoid the need for building new totally automated palnts. Flexible manufacturing system as applied here, has a different connotation vis-a-vis conventional manufacturing industry. Robotic devices, even for stacking jobs, have not been used on a large scale the world over. (author). 6 figs

  18. Design and fabrication of integrated micro/macrostructure for 3D functional gradient systems based on additive manufacturing

    Science.gov (United States)

    Yin, Ming; Xie, Luofeng; Jiang, Weifeng; Yin, Guofu

    2018-05-01

    Functional gradient systems have important applications in many areas. Although a 2D dielectric structure that serves as the gradient index medium for controlling electromagnetic waves is well established, it may not be suitable for application in 3D case. In this paper, we present a method to realize functional gradient systems with 3D integrated micro/macrostructure. The homogenization of the structure is studied in detail by conducting band diagram analysis. The analysis shows that the effective medium approximation is valid even when periodicity is comparable to wavelength. The condition to ensure the polarization-invariant, isotropic, and frequency-independent property is investigated. The scheme for the design and fabrication of 3D systems requiring spatial material property distribution is presented. By using the vat photopolymerization process, a large overall size of macrostructure at the system level and precise fine features of microstructure at the unit cell level are realized, thus demonstrating considerable scalability of the system for wave manipulation.

  19. Modern methods of material accounting for mixed oxide fuel fabrication facility

    International Nuclear Information System (INIS)

    Eggers, R.F.; Pindak, J.L.; Brouns, R.J.; Williams, R.C.; Brite, D.W.; Kinnison, R.R.; Fager, J.E.

    1981-01-01

    The generic requirements loss detection, and response to alarms of a contemporary material control and accounting (MCandA) philosophy have been applied to a mixed oxide fuel fabrication plant to produce a detailed preliminary MCandA system design that is generally applicable to facilities of this type. This paper summarizes and discusses detailed results of the mixed oxide fuel fabrication plant study

  20. Structure and yarn sensor for fabric

    Science.gov (United States)

    Mee, D.K.; Allgood, G.O.; Mooney, L.R.; Duncan, M.G.; Turner, J.C.; Treece, D.A.

    1998-10-20

    A structure and yarn sensor for fabric directly determines pick density in a fabric thereby allowing fabric length and velocity to be calculated from a count of the picks made by the sensor over known time intervals. The structure and yarn sensor is also capable of detecting full length woven defects and fabric. As a result, an inexpensive on-line pick (or course) density measurement can be performed which allows a loom or knitting machine to be adjusted by either manual or automatic means to maintain closer fiber density tolerances. Such a sensor apparatus dramatically reduces fabric production costs and significantly improves fabric consistency and quality for woven or knitted fabric. 13 figs.

  1. Fabrics in Function

    DEFF Research Database (Denmark)

    Bang, Anne Louise

    2007-01-01

    sensing of fabrics in function. It is proposed that tactile and visual sensing of fabrics is a way to investigate and express emotional utility values. The further purpose is to use experiments with repertory grid models as part of the mapping of the entire research project and also as a basis...

  2. Fabrication and Prototyping Lab

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Fabrication and Prototyping Lab for composite structures provides a wide variety of fabrication capabilities critical to enabling hands-on research and...

  3. A New Invention Method to Determine the Reduction Factor for Low Fabric Tension Properties for Head Garment Fabrication

    Directory of Open Access Journals (Sweden)

    Aiman A.F

    2016-01-01

    Full Text Available This paper proposes a new method to determine the reduction factor for producing a head garment with specified targeted pressure output. Pressure garment fabric mostly supplied to the local hospitals with no information of the material properties and the fabrication method generally used a single reduction factor at various body segments. Reduction factor defined as the percentage of reducing the garment size from the original circumference of the body part which contributes to the compression. The objective of this study is to compare the fabrication method of head garment using reduction factor equation from previous research with the new proposed method. The equation to predict the reduction factor requires the parameter of the fabric tension which is obtained from tensile test and radius of curvature of the human body parts. In the new proposed method, a 3D scanning was used for data acquisition to obtain the geometry of the head area. The pressure outputs are measured by a pressure measurement system developed from Flexiforce sensor and Arduino circuit board. By using the equation, the result shows the calculated reduction factor produced an extremely tight head garment compared to the conducted experiments which manage to produce an adequate reduction factor with a targeted pressure output of 20mmHg. The result of the experiment indicates that the reduction factor ranging from 17% to 23% compared to the equation which produces 20% to 47% of reduction factor. As an additional, the proposed experimental method can be used for different type of pressure garment fabrics in order to obtain the relationship between the reduction factor and the circumference of the body parts.

  4. A facile fabrication of multifunctional knit polyester fabric based on chitosan and polyaniline polymer nanocomposite

    Science.gov (United States)

    Tang, Xiaoning; Tian, Mingwei; Qu, Lijun; Zhu, Shifeng; Guo, Xiaoqing; Han, Guangting; Sun, Kaikai; Hu, Xili; Wang, Yujiao; Xu, Xiaoqi

    2014-10-01

    Knit polyester fabric was successively modified and decorated with chitosan layer and polyaniline polymer nanocomposite layer in this paper. The fabric was firstly treated with chitosan to form a stable layer through the pad-dry-cure process, and then the polyaniline polymer nanocomposite layer was established on the outer layer by in situ chemical polymerization method using ammonium persulfate as oxidant and chlorhydric acid as dopant. The surface morphology of coated fabric was characterized by scanning electron microscopy (SEM), and the co-existence of chitosan layer and granular polyaniline polymer nanocomposite was confirmed and well dispersed on the fabric surface. The resultant fabric was endowed with remarkable electrical conductivity properties and efficient water-repellent capability, which also have been found stable after water laundering. In addition, the photocatalytic decomposition activity for reactive red dye was observed when the multifunctional knit polyester fabric was exposed to the illumination of ultraviolet lamp. These results indicated that chitosan and polyaniline polymer nanocomposite could form ideal multifunctional coatings on the surface of knit polyester fabric.

  5. Small-Molecule Organic Photovoltaic Modules Fabricated via Halogen-Free Solvent System with Roll-to-Roll Compatible Scalable Printing Method.

    Science.gov (United States)

    Heo, Youn-Jung; Jung, Yen-Sook; Hwang, Kyeongil; Kim, Jueng-Eun; Yeo, Jun-Seok; Lee, Sehyun; Jeon, Ye-Jin; Lee, Donmin; Kim, Dong-Yu

    2017-11-15

    For the first time, the photovoltaic modules composed of small molecule were successfully fabricated by using roll-to-roll compatible printing techniques. In this study, blend films of small molecules, BTR and PC 71 BM were slot-die coated using a halogen-free solvent system. As a result, high efficiencies of 7.46% and 6.56% were achieved from time-consuming solvent vapor annealing (SVA) treatment and roll-to-roll compatible solvent additive approaches, respectively. After successful verification of our roll-to-roll compatible method on small-area devices, we further fabricated large-area photovoltaic modules with a total active area of 10 cm 2 , achieving a power conversion efficiency (PCE) of 4.83%. This demonstration of large-area photovoltaic modules through roll-to-roll compatible printing methods, even based on a halogen-free solvent, suggests the great potential for the industrial-scale production of organic solar cells (OSCs).

  6. Rapid fabrication of flight worthy composite parts

    Science.gov (United States)

    Jouin, Pierre H.; Heigl, John C.; Youtsey, Timothy L.

    A 3D surfaced-model representation of aircraft composite structural components can be used to generate machining paths in a system which reduces paperwork and errors, and enhances accuracy and speed. Illustrative cases are presented for the use of such a system in the design and production of the Longbow radar housing, the fabrication of the flight test hardware for the 'no tail-rotor' helicopter control system, and the machining of a honeycomb core structure for a composite helicopter rotor blade.

  7. Fabrication of microstamps and patterned cell network

    International Nuclear Information System (INIS)

    Seong, Nak Seon; Pak, James Jung Ho; Choi, Ju Hee; Ahn, Dong June; Hwang, Seong Min; Lee, Kyung J.

    2002-01-01

    Elastomeric stamps with micrometer-sized grids are fabricated for building biological cell networks by design. Polymerized polydimethyl-siloxane (PDMS) stamps are cast in a variety of different molds prepared by micro-electro mechanical systems (MEMS) technology. Micro square-grid patterns of 3-aminopropyl triethoxy silane (APS) are successfully imprinted on glass plates, and patterned networks of cardiac cells are obtained as designed. The resulting cellular networks clearly demonstrate that cell attachment and growth are greatly favored on APS-treated thin tracks. Here, we report the technical details related to the fabrication of microstamps, to the stamping procedure, and to the culture method. The potential applications of patterned cellular networks are also discussed

  8. Fused Filament Fabrication of Prosthetic Components for Trans-Humeral Upper Limb Prosthetics

    Science.gov (United States)

    Lathers, Steven M.

    Presented below is the design and fabrication of prosthetic components consisting of an attachment, tactile sensing, and actuator systems with Fused Filament Fabrication (FFF) technique. The attachment system is a thermoplastic osseointegrated upper limb prosthesis for average adult trans-humeral amputation with mechanical properties greater than upper limb skeletal bone. The prosthetic designed has: a one-step surgical process, large cavities for bone tissue ingrowth, uses a material that has an elastic modulus less than skeletal bone, and can be fabricated on one system. FFF osseointegration screw is an improvement upon the current two-part osseointegrated prosthetics that are composed of a fixture and abutment. The current prosthetic design requires two invasive surgeries for implantation and are made of titanium, which has an elastic modulus greater than bone. An elastic modulus greater than bone causes stress shielding and overtime can cause loosening of the prosthetic. The tactile sensor is a thermoplastic piezo-resistive sensor for daily activities for a prosthetic's feedback system. The tactile sensor is manufactured from a low elastic modulus composite comprising of a compressible thermoplastic elastomer and conductive carbon. Carbon is in graphite form and added in high filler ratios. The printed sensors were compared to sensors that were fabricated in a gravity mold to highlight the difference in FFF sensors to molded sensors. The 3D printed tactile sensor has a thickness and feel similar to human skin, has a simple fabrication technique, can detect forces needed for daily activities, and can be manufactured in to user specific geometries. Lastly, a biomimicking skeletal muscle actuator for prosthetics was developed. The actuator developed is manufactured with Fuse Filament Fabrication using a shape memory polymer composite that has non-linear contractile and passive forces, contractile forces and strains comparable to mammalian skeletal muscle, reaction

  9. Safety aspects of LWR fuel reprocessing and mixed oxide fuel fabrication plants

    International Nuclear Information System (INIS)

    Fischer, M.; Leichsenring, C.H.; Herrmann, G.W.; Schueller, W.; Hagenberg, W.; Stoll, W.

    1977-01-01

    The paper is focused on the safety and the control of the consequences of credible accidents in LWR fuel reprocessing plants and in mixed oxide fuel fabrication plants. Each of these plants serve for many power reactor (about 50.000 Mwel) thus the contribution to the overall risk of nuclear energy is correspondingly low. Because of basic functional differences between reprocessing plants, fuel fabrication plants and nuclear power reactors, the structure and safety systems of these plants are different in many respects. The most important differences that influence safety systems are: (1) Both fuel reprocessing and fabrication plants do not have the high system pressure that is associated with power reactors. (2) A considerable amount of the radioactivity of the fuel, which is in the form of short-lived radionuclides has decayed. Therefore, fuel reprocessing plants and mixed oxide fuel fabrication plants are designed with multiple confinement barriers for control of radioactive materials, but do not require the high-pressure containment systems that are used in LWR plants. The consequences of accidents which may lead to the dispersion of radioactive materials such as chemical explosions, nuclear excursions, fires and failure of cooling systems are considered. A reasonable high reliability of the multiple confinement approach can be assured by design. In fuel reprocessing plants, forced cooling is necessary only in systems where fission products are accumulated. However, the control of radioactive materials can be maintained during normal operation and during the above mentioned accidents, if the dissolver off-gas and vessel off-gas treatment systems provide for effective removal of radioactive iodine, radioactive particulates, nitrogen oxides, tritium and krypton 85. In addition, the following incidents in the dissolver off-gas system itself must be controlled: failures of iodine filters, hydrogen explosion in O 2 - and NOsub(x)-reduction component, decomposition of

  10. Tipping solutions: emerging 3D nano-fabrication/ -imaging technologies

    Directory of Open Access Journals (Sweden)

    Seniutinas Gediminas

    2017-06-01

    Full Text Available The evolution of optical microscopy from an imaging technique into a tool for materials modification and fabrication is now being repeated with other characterization techniques, including scanning electron microscopy (SEM, focused ion beam (FIB milling/imaging, and atomic force microscopy (AFM. Fabrication and in situ imaging of materials undergoing a three-dimensional (3D nano-structuring within a 1−100 nm resolution window is required for future manufacturing of devices. This level of precision is critically in enabling the cross-over between different device platforms (e.g. from electronics to micro-/nano-fluidics and/or photonics within future devices that will be interfacing with biological and molecular systems in a 3D fashion. Prospective trends in electron, ion, and nano-tip based fabrication techniques are presented.

  11. Marginal accuracy of computer-aided design- and computer-aided manufacturing-fabricated full-arch zirconia restoration

    Directory of Open Access Journals (Sweden)

    Juntavee N

    2018-02-01

    Full Text Available Niwut Juntavee,1 Issarawas Sirisathit2 1Department of Prosthodontics, 2Division of Biomaterials and Prosthodontics Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand Objective: This study evaluated marginal accuracy of full-arch zirconia restoration fabricated from two digital computer-aided design and computer-aided manufacturing (CAD-CAM systems (Trios-3 and CS3500 in comparison to conventional cast metal restoration. Materials and methods: A stainless steel model comprising two canine and two molar abutments was used as a master model for full-arch reconstruction. The canine and molar abutments were machined in a cylindrical shape with 5° taper and chamfer margin. The CAD-CAM systems based on the digital approach were used to construct the full-arch zirconia restoration. The conventional cast metal restoration was fabricated according to a conventional lost-wax technique using nickel–chromium alloys. Ten restorations were fabricated from each system. The marginal accuracy of each restoration was determined at four locations for each abutment. An analysis of variance (ANOVA and Tukey’s honest significant difference (HSD multiple comparisons were used to determine statistically significant difference at 95% confidence interval. Results: The mean values of marginal accuracy of restorations fabricated from conventional casting, Trios-3, and CS3500 were 48.59±4.16 μm, 53.50±5.66 μm, and 56.47±5.52 μm, respectively. ANOVA indicated significant difference in marginal fit of restorations among various systems. The marginal discrepancy of zirconia restoration fabricated from the CS3500 system demonstrated significantly larger gap than that fabricated from the 3Shape system (p<0.05. Tukey’s HSD multiple comparisons indicated that the zirconia restoration fabricated from either CS3500 or Trios-3 demonstrated a significantly larger marginal gap than the conventional cast metal restoration (p<0.05. Conclusion: Full

  12. Development of Hi-Tech ceramics fabrication technologies - Development of advanced nuclear materials

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Thae Kap; Park, Ji Youn; Kim, Sun Jae; Kim, Kyong Ho; Jung, Choong Hwan; Oh, Seok Jin [Korea Atomic Energy Res. Inst., Taejon (Korea, Republic of)

    1994-07-15

    The objective of the present work is to prepare the foundation of hi-tech ceramics fabrication technologies through developing important processes i.e., tape casting, sol-gel, single crystal growing, compacting and sintering, and grinding and machining processes. Tape casting process is essential to manufacture hard and functional thin plates and structural elements for some composite materials. For the fabrication of spherical mono-sized micropowders of oxides, sol-gel process has widely been used. Piezoelectric elements that are the core parts of the sensors of LPMS (loose part monitoring system) and ALMS (acoustic leakage monitoring system) are used in single crystal forms. Compacting and sintering processes are general methods for fabricating structural parts using powders. Grinding and machining processes are important to achieve the final dimensions and surface properties of the parts. (Author).

  13. 14 CFR 29.605 - Fabrication methods.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fabrication methods. 29.605 Section 29.605... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Design and Construction General § 29.605 Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a fabrication process...

  14. Complete Dentures Fabricated with CAD/CAM Technology and a Traditional Clinical Recording Method.

    Science.gov (United States)

    Janeva, Nadica; Kovacevska, Gordana; Janev, Edvard

    2017-10-15

    The introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture (CD) fabrication ushered in a new era in removable prosthodontics. Commercially available CAD/CAM denture systems are expected to improve upon the disadvantages associated with conventional fabrication. The purpose of this report is to present the workflow involved in fabricating a CD with a traditional clinical recording method and CAD/CAM technology and to summarize the advantages to the dental practitioner and the patient.

  15. Dissolvable microneedle fabrication using piezoelectric dispensing technology.

    Science.gov (United States)

    Allen, Evin A; O'Mahony, Conor; Cronin, Michael; O'Mahony, Thomas; Moore, Anne C; Crean, Abina M

    2016-03-16

    Dissolvable microneedle (DMN) patches are novel dosage forms for the percutaneous delivery of vaccines. DMN are routinely fabricated by dispensing liquid formulations into microneedle-shaped moulds. The liquid formulation within the mould is then dried to create dissolvable vaccine-loaded microneedles. The precision of the dispensing process is critical to the control of formulation volume loaded into each dissolvable microneedle structure. The dispensing process employed must maintain vaccine integrity. Wetting of mould surfaces by the dispensed formulation is also an important consideration for the fabrication of sharp-tipped DMN. Sharp-tipped DMN are essential for ease of percutaneous administration. In this paper, we demonstrate the ability of a piezoelectric dispensing system to dispense picolitre formulation volumes into PDMS moulds enabling the fabrication of bilayer DMN. The influence of formulation components (trehalose and polyvinyl alcohol (PVA) content) and piezoelectric actuation parameters (voltage, frequency and back pressure) on drop formation is described. The biological integrity of a seasonal influenza vaccine following dispensing was investigated and maintained voltage settings of 30 V but undermined at higher settings, 50 and 80 V. The results demonstrate the capability of piezoelectric dispensing technology to precisely fabricate bilayer DMN. They also highlight the importance of identifying formulation and actuation parameters to ensure controlled droplet formulation and vaccine stabilisation. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Design, fabrication and characterization of LTCC-based electromagnetic microgenerators

    International Nuclear Information System (INIS)

    Gierczak, M; Markowski, P; Dziedzic, A

    2016-01-01

    Design, manufacturing process and properties of electromagnetic microgenerators fabricated in LTCC (Low Temperature Co-fired Ceramics) technology are presented in this paper. Electromagnetic microgenerators consist of planar coils spatially arranged on several layers of LTCC and of a multipole permanent magnet. Two different patterns of coils with 2-, 8-,10- and 12-layers and outer diameter of 50 mm were designed and fabricated. Silver-based pastes ESL 903-A or DuPont 6145 were used. In order to estimate the inductance of a single spatial coil the Greenhouse (self-inductance) and Hoer (mutual inductance) calculation methods were used. To verify the calculation results a single-layer coil was fabricated for each pattern and its inductance was measured using the precision RLC Meter. Fabricated LTCC microgenerators with embedded coils allow to generate voltage higher than ten volts and the electrical output power of approximately 600 mW at the rotor rotation speed of 12 thousands rpm. The self-made system was used for characterization of LTCC-based electromagnetic microgenerators. (paper)

  17. Fabrication of particulate metal fuel for fast burner reactors

    International Nuclear Information System (INIS)

    Ryu, Ho Jin; Lee, Sun Yong; Kim, Jong Hwan; Woo, Yoon Myung; Ko, Young Mo; Kim, Ki Hwan; Park, Jong Man; Lee, Chan Bok

    2012-01-01

    U Zr metallic fuel for sodium cooled fast reactors is now being developed by KAERI as a national R and D program of Korea. In order to recycle transuranic elements (TRU) retained in spent nuclear fuel, remote fabrication capability in a shielded hot cell should be prepared. Moreover, generation of long lived radioactive wastes and loss of volatile species should be minimized during the recycled fuel fabrication step. Therefore, innovative fuel concepts should be developed to address the fabrication challenges pertaining to TRU while maintaining good performances of metallic fuel. Particulate fuel concepts have already been proposed and tested at several experimental fast reactor systems and vipac ceramic fuel of RIAR, Russia is one of the examples. However, much less work has been reported for particulate metallic fuel development. Spherical uranium alloy particles with various diameters can be easily produced by the centrifugal atomization technique developed by KAERI. Using the atomized uranium and uranium zirconium alloy particles, we fabricated various kinds of powder pack, powder compacts and sintered pellets. The microstructures and properties of the powder pack and pellets are presented

  18. The oxidation behavior of classical thermal barrier coatings exposed to extreme temperature

    Directory of Open Access Journals (Sweden)

    Alina DRAGOMIRESCU

    2017-03-01

    Full Text Available Thermal barrier coatings (TBC are designed to protect metal surfaces from extreme temperatures and improve their resistance to oxidation during service. Currently, the most commonly used systems are those that have the TBC structure bond coat (BC / top coat (TC layers. The top coat layer is a ceramic layer. Oxidation tests are designed to identify the dynamics of the thermally oxide layer (TGO growth at the interface of bond coat / top coat layers, delamination mechanism and the TBC structural changes induced by thermal conditions. This paper is a short study on the evolution of aluminum oxide protective layer along with prolonged exposure to the testing temperature. There have been tested rectangular specimens of metal super alloy with four surfaces coated with a duplex thermal barrier coating system. The specimens were microscopically and EDAX analyzed before and after the tests. In order to determine the oxide type, the samples were analyzed using X-ray diffraction. The results of the investigation are encouraging for future studies. The results show a direct relationship between the development of the oxide layer and long exposure to the test temperature. Future research will focus on changing the testing temperature to compare the results.

  19. 14 CFR 27.605 - Fabrication methods.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fabrication methods. 27.605 Section 27.605... STANDARDS: NORMAL CATEGORY ROTORCRAFT Design and Construction General § 27.605 Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a fabrication process (such as...

  20. 14 CFR 25.605 - Fabrication methods.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fabrication methods. 25.605 Section 25.605... STANDARDS: TRANSPORT CATEGORY AIRPLANES Design and Construction General § 25.605 Fabrication methods. (a) The methods of fabrication used must produce a consistently sound structure. If a fabrication process...

  1. Practical application of the dose limitation system in a uranium fuel fabrication plant

    International Nuclear Information System (INIS)

    Auricchio, S.; Cantoro, N.

    1982-01-01

    ICRP Publication 26 was published when the nuclear operators and the different national regulatory bodies were already in a position to understand the proposed dose limitation system and to apply it to nuclear activities. In Italy the basic principle of limiting individual risks and the search for increased protection were already applied in the radiation analysis of nuclear plants. These principles were applied during design (1972-74) and operation (1974-80) of the industrial fuel-element fabrication plant of the company Fabbricazioni Nucleari (F.N.) in Bosco Marengo. The paper reports on the criteria followed in the design stage, the organization and methods adopted for reducing the doses during operation, and the results achieved after a few years of plant activity. In view of the purely technical nature of this paper, the first principle of the dose limitation system (justification), which is more a political issue, is not taken into consideration; however, an assessment of the Italian context as at the end of the 1960s shows that the principle of justification of a practice was adequately taken into account when the construction of the F.N. plant was decided on. (author)

  2. Prevalência da infecção pelo HIV em pacientes internados por tuberculose Prevalence of HIV infection in patients hospitalized due to tuberculosis

    Directory of Open Access Journals (Sweden)

    GUILHERME FREIRE GARCIA

    2000-08-01

    Full Text Available Objetivos: Verificar a prevalência da co-infecção tuberculose (TBC/HIV e a capacidade da anamnese em detectar a infecção pelo HIV em pacientes internados por TBC. Local: Hospital Eduardo de Menezes, Belo Horizonte, MG, referência para TBC e SIDA. Material e métodos: Todos os pacientes internados com TBC na enfermaria de pneumologia foram avaliados prospectivamente no período de 1/1/1997 até 31/1/1998, com anamnese dirigida para fatores de risco para SIDA, TBC, tratamentos anteriores e abandonos de tratamento para TBC, e verificadas as formas clínicas de TBC. Foram excluídos pacientes com doenças marcadoras de SIDA com exceção da TBC, ou com sorologia anti-HIV realizada anteriormente. Foram realizadas sorologias anti-HIV (ELISA e, quando positivas, confirmadas pelo teste Western-Blot. Os testes do qui-quadrado e de Fisher foram usados para análise estatística. Resultados: Sessenta e cinco pacientes avaliados foram divididos em grupo I (sorologia positiva para HIV, n = 6 e grupo II (sorologia negativa para HIV, n = 59. Não houve diferença significativa entre os dois grupos quanto a fatores de risco para SIDA, TBC, abandonos de tratamento ou tratamentos anteriores para TBC ou formas clínicas de TBC. Conclusões: Devido à alta prevalência da infecção pelo HIV (9,2% no grupo estudado, estes achados reforçam as orientações do Consenso Brasileiro de Tuberculose no sentido de: 1 a anamnese não consegue detectar uma parcela significativa dos pacientes com co-infecção TBC/HIV; e: 2 a solicitação de sorologia anti-HIV deve ser feita de forma rotineira em todos os pacientes com TBC ativa.Objectives: To verify the prevalence of tuberculosis (TB/HIV co-infection and the ability of the clinical history to detect the HIV infection in TB inpatients. Setting: Eduardo de Menezes Hospital, reference for both TB and AIDS. Patients and methods: All patients admitted with TB in a pneumology ward were evaluated prospectively from 1

  3. Numerical Study of the Effects of Thermal Barrier Coating and Turbulence Intensity on Cooling Performances of a Nozzle Guide Vane

    Directory of Open Access Journals (Sweden)

    Prasert Prapamonthon

    2017-03-01

    Full Text Available This work presents a numerical investigation of the combined effects of thermal barrier coating (TBC with mainstream turbulence intensity (Tu on a modified vane of the real film-cooled nozzle guide vane (NGV reported by Timko (NASA CR-168289. Using a 3D conjugate heat transfer (CHT analysis, the NGVs with and without TBC are simulated at three Tus (Tu = 3.3%, 10% and 20%. The overall cooling effectiveness, TBC effectiveness and heat transfer coefficient are analyzed and discussed. The results indicate the following three interesting phenomena: (1 TBC on the pressure side (PS is more effective than that on the suction side (SS due to a fewer number of film holes on the SS; (2 for all three Tus, the variation trends of the overall cooling effectiveness are similar, and TBC plays the positive and negative roles in heat flux at the same time, and significantly increases the overall cooling effectiveness in regions cooled ineffectively by cooling air; (3 when Tu increases, the TBC effect is more significant, for example, at the highest Tu (Tu = 20% the overall cooling effectiveness can increase as much as 24% in the film cooling ineffective regions, but near the trailing edge (TE and the exits and downstream of film holes on the SS, this phenomenon is slight.

  4. A method for the easy fabrication of all-ceramic bridges with the Cerec system.

    Science.gov (United States)

    Kurbad, A; Schnock, H A

    2009-01-01

    Both pressing technology and CAD/CAM methods have proven themselves clinically for the fabrication of all-ceramic restorations. The advantages of the Cerec technology for the economic fabrication of all-ceramic bridges can be exploited by the use of burn-out blanks of polymer material. The milling process of very hard ceramics in the milling unit, which has some disadvantages, is replaced by the pressing process and makes the IPS e.max press material accessible to CAD/CAM users, primarily for extending the range of indications to splinted crowns and small all-ceramic bridges.

  5. Device fabrication by plasma etching

    International Nuclear Information System (INIS)

    Mogab, C.J.

    1980-01-01

    Plasma etching as applied to many of the materials encountered in the fabrication of LSI's is complicated by loading effect-the dependence of etch rate on the integrated surface area to be etched. This problem is alleviated by appropriate choice of etchant and etching conditions. Appropriate choice of system parameters, generally most concerned with the inherent lifetime of etchant species, may also result in improvement of etch rate uniformity on a wafer-by-wafer basis

  6. Chilean fuel elements fabrication progress report

    International Nuclear Information System (INIS)

    Baeza, J.; Contreras, H.; Chavez, J.; Klein, J.; Mansilla, R.; Marin, J.; Medina, R.

    1993-01-01

    Due to HEU-LEU core conversion necessity for the Chilean MTR reactors, the Fuel Elements Plant is being implemented to LEU nuclear fuel elements fabrication. A glove box line for powder-compact processing designed at CCHEN, which supposed to operate under an automatic control system, is at present under initial tests. Results of first natural uranium fuel plates manufacturing runs are shown

  7. Design verification and fabrication of active control systems for the DAST ARW-2 high aspect ratio wing. Part 2: Appendices

    Science.gov (United States)

    Mcgehee, C. R.

    1986-01-01

    This is Part 2-Appendices of a study conducted under Drones for Aerodynamic and Structural Testing (DAST) Program to accomplish the final design and hardware fabrication for four active control systems compatible with and ready for installation in the NASA Aeroelastic Research Wing No. 2 (ARW-2) and Firebee II drone flight test vehicle. The wing structure was designed so that Active Control Systems (ACS) are required in the normal flight envelope by integrating control system design with aerodynamics and structure technologies. The DAST ARW-2 configuration uses flutter suppression, relaxed static stability, and gust and maneuver load alleviation ACS systems, and an automatic flight control system. Performance goals and criteria were applied to individual systems and the systems collectively to assure that vehicle stability margins, flutter margins, flying qualities, and load reductions were achieved.

  8. Mask fabrication process

    Science.gov (United States)

    Cardinale, Gregory F.

    2000-01-01

    A method for fabricating masks and reticles useful for projection lithography systems. An absorber layer is conventionally patterned using a pattern and etch process. Following the step of patterning, the entire surface of the remaining top patterning photoresist layer as well as that portion of an underlying protective photoresist layer where absorber material has been etched away is exposed to UV radiation. The UV-exposed regions of the protective photoresist layer and the top patterning photoresist layer are then removed by solution development, thereby eliminating the need for an oxygen plasma etch and strip and chances for damaging the surface of the substrate or coatings.

  9. Material control in nuclear fuel fabrication facilities. Part II. Accountability, instrumentation and measurement techniques in fuel fabrication facilities

    International Nuclear Information System (INIS)

    Borgonovi, G.M.; McCartin, T.J.; McDaniel, T.; Miller, C.L.; Nguyen, T.

    1978-01-01

    This report describes the measurement techniques, the instrumentation, and the procedures used in accountability and control of nuclear materials, as they apply to fuel fabrication facilities. A general discussion is given of instrumentation and measurement techniques which are presently used being considered for fuel fabrication facilities. Those aspects which are most significant from the point of view of satisfying regulatory constraints have been emphasized. Sensors and measurement devices have been discussed, together with their interfacing into a computerized system designed to permit real-time data collection and analysis. Estimates of accuracy and precision of measurement techniques have been given, and, where applicable, estimates of associated costs have been presented. A general description of material control and accounting is also included. In this section, the general principles of nuclear material accounting have been reviewed first (closure of material balance). After a discussion of the most current techniques used to calculate the limit of error on inventory difference, a number of advanced statistical techniques are reviewed. The rest of the section deals with some regulatory aspects of data collection and analysis, for accountability purposes, and with the overall effectiveness of accountability in detecting diversion attempts in fuel fabrication facilities. A specific example of application of the accountability methods to a model fuel fabrication facility is given. The effect of random and systematic errors on the total material uncertainty has been discussed, together with the effect on uncertainty of the length of the accounting period

  10. Material control in nuclear fuel fabrication facilities. Part II. Accountability, instrumentation and measurement techniques in fuel fabrication facilities

    Energy Technology Data Exchange (ETDEWEB)

    Borgonovi, G.M.; McCartin, T.J.; McDaniel, T.; Miller, C.L.; Nguyen, T.

    1978-01-01

    This report describes the measurement techniques, the instrumentation, and the procedures used in accountability and control of nuclear materials, as they apply to fuel fabrication facilities. A general discussion is given of instrumentation and measurement techniques which are presently used being considered for fuel fabrication facilities. Those aspects which are most significant from the point of view of satisfying regulatory constraints have been emphasized. Sensors and measurement devices have been discussed, together with their interfacing into a computerized system designed to permit real-time data collection and analysis. Estimates of accuracy and precision of measurement techniques have been given, and, where applicable, estimates of associated costs have been presented. A general description of material control and accounting is also included. In this section, the general principles of nuclear material accounting have been reviewed first (closure of material balance). After a discussion of the most current techniques used to calculate the limit of error on inventory difference, a number of advanced statistical techniques are reviewed. The rest of the section deals with some regulatory aspects of data collection and analysis, for accountability purposes, and with the overall effectiveness of accountability in detecting diversion attempts in fuel fabrication facilities. A specific example of application of the accountability methods to a model fuel fabrication facility is given. The effect of random and systematic errors on the total material uncertainty has been discussed, together with the effect on uncertainty of the length of the accounting period.

  11. Tuberculosis en pacientes con diabetes mellitus: Un estudio epidemiológico y clínico en el Hospital Nacional Cayetano Heredia

    Directory of Open Access Journals (Sweden)

    Juan Luis DELGADO ROSPIGLIOSI

    2006-07-01

    Full Text Available Objetivo: Describir las características epidemiológicas y clínicas de pacientes diabéticos con tuberculosis atendidos en el Hospital Nacional Cayetano Heredia (HNCH. Material y Métodos: Estudio retrospectivo, observacional, descriptivo. Se identificaron los "casos" (pacientes diabéticos con TBC revisando los registros del Servicio de Endocrinología, Servicios de hospitalización de Medicina y del Departamento de Enfermedades Infecciosas y Tropicales del HNCH atendidos durante el periodo de 1997 al 2003. Resultados: Se encontraron 85 episodios de TBC en 74 historias clínicas revisadas. El promedio de edad fue de 49,4 +12,8 años; 48/74 (65% fueron hombres y 26/74 (35% mujeres. 72/74 (97,3% pacientes presentaron diabetes mellitus tipo 2. El tiempo promedio de enfermedad diabética previo al desarrollo de TBC fue de 4.2 +4 años. 75/85 (88,2% episodios presentaron TBC pulmonar, habiendo confirmación bacteriológica en el 51,3% de estos casos. 59/85 (69% casos no cumplían regularmente con el tratamiento indicado para la diabetes y 60/85 (71% tenían mal control metabólico al desarrollar TBC. 31/74 (42% pacientes fueron hospitalizados por TBC, asociándose cetoacidosis diabética (CAD en el 51,4% de las hospitalizaciones por esta causa. La TBC puede ser causa importante desencadenante de CAD en nuestro medio. La tasa de fracasos al tratamiento fue de 15/85 (17,6%; hubo sospecha de TB-MDR en 13/74 pacientes (17,6%. La tasa de recaídas fue de 15/74 (20,3%. Fallecieron 3/74 pacientes (4% durante el período de estudio. Conclusiones: Pacientes diabéticos mal controlados desarrollan TBC con una elevada tasa de recaídas, fracasos y TB-MDR, con alta sospecha de contagio intrahospitalario. (Rev Med Hered 2006;17:132-140.

  12. Evaluación del efecto residual del Temephos en larvas de Aedes aegypti en Lima, Perú

    Directory of Open Access Journals (Sweden)

    Miriam Palomino S

    2006-07-01

    Full Text Available El temephos ha sido usado como la única estrategia de control para Aedes aegypti en Lima durante los últimos años. Objetivo: Evaluar la eficacia residual de temephos para el control de Ae. aegypti en condiciones de campo y laboratorio en Lima, Perú. Materiales y métodos: Se eligieron ocho tanques bajos de concreto (TBC depósitos predominantemente infestados con Ae. aegypti en el distrito de San Juan de Lurigancho, situado al norte del área suburbana de Lima. Se cuantificó el número de larvas con ayuda de una red de mano y luego fueron devueltas a los TBC. Los TBC fueron tratados con temephos a una dosis de 1 ppm en el día cero (0. Se evaluó la mortalidad de las larvas salvajes a 24, 48 y 72 horas y se hizo un seguimiento periódico cada siete días hasta las 14 semanas. Al mismo tiempo y en forma semanal se recogieron 500 mL de agua de cada TBC tratado y fueron enviados al laboratorio para los bioensayos (exposición de 25 larvas durante 24 a 48 horas y registro de mortalidad. Resultados: Todos los TBC estuvieron infestados (mediana de 43,5 larvas. La mortalidad en los TBC a 24 horas fue 99,7% y no se evidenció recolonización de los TBC hasta la 14.ª semana. Sin embargo, en el laboratorio se evidencia disminución semanal de 11% de la mortalidad desde la 7.ª semana. La mortalidad en la semana número 14 estuvo asociada de forma inversa con la frecuencia de recambio de agua en los TBC (p<0,05. Conclusiones: No hubo evidencia en condiciones de campo de eficacia residual disminuida del temephos a la 14.a semana de aplicación. Este tipo de estudios deberían hacerse de manera rutinaria para vigilar la efectividad del larvicida temephos en Lima.

  13. Development of a Multi-User Polyimide-MEMS Fabrication Process and its Application to MicroHotplates

    KAUST Repository

    Lizardo, Ernesto B.

    2013-01-01

    Micro-electro-mechanical systems (MEMS) became possible thanks to the silicon based technology used to fabricate integrated circuits. Originally, MEMS fabrication was limited to silicon based techniques and materials, but the expansion of MEMS

  14. Fabrication of new joints for SST-1 TF coil winding packs

    International Nuclear Information System (INIS)

    Prasad, Upendra; Sharma, A.N.; Patel, Dipak; Doshi, Kalpesh; Khristi, Yohan; Varmora, Pankaj; Chauhan, Pradeep; Jadeja, S.J.; Gupta, Pratibha; Pradhan, S.

    2013-01-01

    Highlights: • We have carried out work related with sub-nanoohm joints for superconducting Tokamak winding packs. • We have established fine tune QA/QC procedures for sub-nanoohm joints fabrication. • We have optimised welding parameters for cable in conduit conductors for fusion relevant magnets. • We have established precised measurement data acquisition system for low resistance measurements at cryogenic temperature. -- Abstract: The Toroidal Field (TF) magnet system of SST-1 has sixteen NbTi/Cu based coils with about one hundred Inter-Pancake (IP) and Inter-Coil (IC) joints. New box type helium leak tight, low DC resistance joints have been designed, fabricated and tested at 5 K temperature and 10 kA DC transport current. The prototype of this joint has been validated in laboratory as well as on spare TF coil winding pack. Moreover, the performance of these joints has been realised and validated on actual sixteen TF winding packs, the joint resistance of ∼0.5 nΩ repeatedly measured on hundreds of IP joints. The quality of terminations and joints was ensured at various stages of fabrication. The quality of joint box material was ensured by visual inspection, chemical analysis, radiography test, ultrasonic test, eddy current test, etc. This paper describes joint design drivers, joint design detail, prototype joint fabrication processes, quality assurance (QA)/quality control (QC) adopted during prototype and actual joint fabrication process, joint resistance measurement on actual TF coils and analysis of measured joint resistance in detail

  15. 14 CFR 23.605 - Fabrication methods.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

  16. The design and fabrication of two portal vein flow phantoms by different methods

    Energy Technology Data Exchange (ETDEWEB)

    Yunker, Bryan E., E-mail: bryan.yunker@ucdenver.edu; Lanning, Craig J.; Shandas, Robin; Hunter, Kendall S. [Department of Bioengineering, University of Colorado – Denver/Anschutz, 12700 East 19th Avenue, MS 8607, Aurora, Colorado 80045 (United States); Dodd, Gerald D., E-mail: gerald.dodd@ucdenver.edu; Chang, Samuel; Scherzinger, Ann L. [Department of Radiology, University of Colorado – SOM, 12401 East 17th Avenue, Mail Stop L954, Aurora, Colorado 80045 (United States); Chen, S. James, E-mail: james.chen@ucdenver.edu [Department of Medicine, University of Colorado Denver, Colorado 80045 and Department of Medicine/Cardiology, University of Colorado – SOM, 12401 East 17th Avenue, Mail Stop B132, Aurora, Colorado 80045 (United States); Feng, Yusheng, E-mail: yusheng.feng@utsa.edu [Department of Mechanical Engineering, University of Texas – San Antonio, One UTSA Circle, Mail Stop: AET 2.332, San Antonio, Texas 78249–0670 (United States)

    2014-02-15

    Purpose: This study outlines the design and fabrication techniques for two portal vein flow phantoms. Methods: A materials study was performed as a precursor to this phantom fabrication effort and the desired material properties are restated for continuity. A three-dimensional portal vein pattern was created from the Visual Human database. The portal vein pattern was used to fabricate two flow phantoms by different methods with identical interior surface geometry using computer aided design software tools and rapid prototyping techniques. One portal flow phantom was fabricated within a solid block of clear silicone for use on a table with Ultrasound or within medical imaging systems such as MRI, CT, PET, or SPECT. The other portal flow phantom was fabricated as a thin walled tubular latex structure for use in water tanks with Ultrasound imaging. Both phantoms were evaluated for usability and durability. Results: Both phantoms were fabricated successfully and passed durability criteria for flow testing in the next project phase. Conclusions: The fabrication methods and materials employed for the study yielded durable portal vein phantoms.

  17. Novel fiber Bragg grating fabrication system for long gratings with independent apodization and with local phase and wavelength control.

    Science.gov (United States)

    Chung, K M; Dong, L; Lu, C; Tam, H Y

    2011-06-20

    We proposed and demonstrated a novel practical fiber Bragg grating (FBG) fabrication setup constructed with high performance linear stages, piezoelectric translation (PZT) stages, and a highly stable continuous wave laser. The FBG fabrication system enables writing of long FBGs by a continuous translate-and-write process and allows implementation of arbitrary chirp and apodization. A key innovation is that the local Bragg wavelength is controlled by a simple movement of the phase mask by a PZT in the direction perpendicular to its surface. The focus position of the two writing beams is not changed during the Bragg wavelength change, an intrinsic feature of the design, ensuring simplicity, robustness and stability. Apodization can be achieved by vibrating the phase mask in the direction parallel to its surface by a PZT. Phase steps can also be inserted in FBGs at any desired locations by stepping the same PZT. A long uniform FBG and a linearly chirped FBG are written to demonstrate the performance of the setup.

  18. STRESS - STRAIN CURVE ANALYSIS OF WOVEN FABRICS MAD E FROM COMBED YARNS TYPE WOOL

    Directory of Open Access Journals (Sweden)

    VÎLCU Adrian

    2014-05-01

    Full Text Available The paper analyses the tensile behavior of woven fabrics made from 45%Wool + 55% PES used for garments. Analysis of fabric behavior during wearing has shown that these are submitted to simple and repeated uni-axial or bi-axial tensile strains. The level of these strains is often within the elastic limit, rarely going over yielding. Therefore the designer must be able to evaluate the mechanical behavior of such fabrics in order to control the fabric behavior in the garment. This evaluation is carried out based on the tensile testing, using certain indexes specific to the stress-strain curve. The paper considers an experimental matrix based on woven fabrics of different yarn counts, different or equal yarn count for warp and weft systems and different structures. The fabrics were tested using a testing machine and the results were then compared in order to determine the fabrics’ tensile behavior and the factors of influence that affect it.From the point of view of tensile testing, the woven materials having twill weave are preferable because this type of structure is characterized by higher durability and better yarn stability in the fabric. In practice, the woven material must exhibit an optimum behavior to repeated strains, flexions and abrasions during wearing process. The analysis of fabrics tensile properties studied by investigation of stress-strain diagrams reveals that the main factors influencing the tensile strength are: yarns fineness, technological density of those two systems of yarns and the weaving type.

  19. Fabrication of Hydrophobic Membrane for the Separation of n-Hexane/Water Mixture Using Novel Oleophilic Nanoparticle and Kevlar Fabric, as a Superior Support

    Directory of Open Access Journals (Sweden)

    Hanieh Karimnezhad

    2017-07-01

    Full Text Available The fabrication of functionalized membranes with hydrophobic/oleophilic surfaces for the elimination of n-hexane from water using para-aminobenzoate alumoxane, boehmite-epoxide and a novel nanoparticle, i.e., Stearate Alumoxane by a simple coating technique, is reported here. FTIR was used to characterize nanoparticles. SEM and contact angle measurement analyses were used to identify the nanocomposite membranes. The concentrations of oil in permeate and retentate were measured by UV/vis spectrophotometer. The morphology of Stearate alumoxane nanoparticles was investigated by means of SEM images. The composed film of nanoparticles on the Kevlar fabric was hydrophobic with water contact angle of ~ 145° and oleophilic with oil contact angle of ~ 0º. In addition, the membranes retained stable hydrophobicity and high separation efficiency even after employing for 6 times. Applying these properties, a setup was considered using the functionalized Kevlar fabric to separate oil through down to a collector and leave water drops. Our batch filtration system was exclusively gravity-driven. The achieved separation system can separate the oily water mixture (with the concentration of 20 % (v/v n-hexane in water, effectively with a separation efficiency of 84%.

  20. Cylindrical fabric-confined soil structures

    Science.gov (United States)

    Harrison, Richard A.

    A cylindrical fabric-soil structural concept for implementation on the moon and Mars which provides many advantages is proposed. The most efficient use of fabric is to fashion it into cylindrical tubes, creating cylindrical fabric-confined soil structures. The length, diameter, and curvature of the tubes will depend on the intended application. The cylindrical hoop forces provide radial confinement while end caps provide axial confinement. One of the ends is designed to allow passage of the soil into the fabric tube before sealing. Transportation requirements are reduced due to the low mass and volume of the fabric. Construction requirements are reduced due to the self-erection capability via the pneumatic exoskeleton. Maintenance requirements are reduced due to the passive nature of the concept. The structure's natural ductility is well suited for any seismic activity.

  1. Development of sensitive holographic devices for physiological metal ion detection

    Science.gov (United States)

    Sabad-e.-Gul; Martin, Suzanne; Cassidy, John; Naydenova, Izabela

    2017-08-01

    The development of selective alkali metal ions sensors in particular is a subject of significant interest. In this respect, the level of blood electrolytes, particularly H+, Na+, K+ and Cl- , is widely used to monitor aberrant physiologies associated with pulmonary emphysema, acute and chronic renal failure, heart failure, diabetes. The sensors reported in this paper are created by holographic recording of surface relief structures in a self-processing photopolymer material. The structures are functionalized by ionophores dibenzo-18-crown-6 (DC) and tetraethyl 4-tert-butylcalix[4]arene (TBC) in plasticised polyvinyl chloride (PVC) matrix. Interrogation of these structures by light allows indirect measurements of chemical analytes' concentration in real time. We present results on the optimisation and testing of the holographic sensor. A self-processing acrylamide-based photopolymer was used to fabricate the required photonic structures. The performance of the sensors for detection of K+ and Na+ was investigated. It was observed that the functionalisation with DC provides a selective response of the devices to K+ over Na+ and TBC coated surface structures are selectively sensitive to Na+. The sensor responds to Na+ within the physiological ranges. Normal levels of Na+ and K+ in human serum lie within the ranges 135-148mM and 3.5-5.3 mM respectively.

  2. Thermal barrier coatings - Technology for diesel engines

    International Nuclear Information System (INIS)

    Harris, D.H.; Lutz, J.

    1988-01-01

    Thermal Barrier Coatings (TBC) are a development of the aerospace industry primarily aimed at hot gas flow paths in turbine engines. TBC consists of zirconia ceramic coatings applied over (M)CrAlY. These coatings can provide three benefits: (1) a reduction of metal surface operating temperatures, (2) a deterrent to hot gas corrosion, and (3) improved thermal efficiencies. TBC brings these same benefits to reciprocal diesel engines but coating longevity must be demonstrated. Diesels require thicker deposits and have challenging geometries for the arc-plasma spray (APS) deposition process. Different approaches to plasma spraying TBC are required for diesels, especially where peripheral edge effects play a major role. Bondcoats and ceramic top coats are modified to provide extended life as determined by burner rig tests, using ferrous and aluminum substrates

  3. Design, fabrication and comparison of two power combiners: cylindrical and coaxial cavities

    Directory of Open Access Journals (Sweden)

    A M Poursaleh

    2017-08-01

    Full Text Available Resonant structure is one of the proposed methods in combining power in RF systems of  RF accelerators. In this structure, fabrication of RF power divider or combiner using coaxial and cylindrical cavity is important. In this study, two combiners, in the same frequency band, are designed and fabricated; and their results are compared. The experimental results confirmed the simulation results and showed that compared with cyclical cavity, the power combiner with coaxial cavity is smaller, more easily adjustable, and is more suitable for use in RF systems of RF accelerators

  4. Fabrication challenges for indium phosphide microsystems

    International Nuclear Information System (INIS)

    Siwak, N P; Fan, X Z; Ghodssi, R

    2015-01-01

    From the inception of III–V microsystems, monolithically integrated device designs have been the motivating drive for this field, bringing together the utility of single-chip microsystems and conventional fabrication techniques. Indium phosphide (InP) has a particular advantage of having a direct bandgap within the low loss telecommunication wavelength (1550 nm) range, able to support passive waveguiding and optical amplification, detection, and generation depending on the exact alloy of In, P, As, Ga, or Al materials. Utilizing epitaxy, one can envision the growth of a substrate that contains all of the components needed to establish a single-chip optical microsystem, containing detectors, sources, waveguides, and mechanical structures. A monolithic InP MEMS system has, to our knowledge, yet to be realized due to the significant difficulties encountered when fabricating the integrated devices. In this paper we present our own research and consolidate findings from other research groups across the world to give deeper insight into the practical aspects of InP monolithic microsystem development: epitaxial growth of InP-based alloys, etching techniques, common MEMS structures realized in InP, and future applications. We pay special attention to shedding light on considerations that must be taken when designing and fabricating a monolithic InP MEMS device. (topical review)

  5. Potassium-argon (argon-argon), structural fabrics

    Science.gov (United States)

    Cosca, Michael A.; Rink, W. Jack; Thompson, Jereon

    2014-01-01

    Definition: 40Ar/39Ar geochronology of structural fabrics: The application of 40Ar/39Ar methods to date development of structural fabrics in geologic samples. Introduction: Structural fabrics develop during rock deformation at variable pressures (P), temperatures (T), fluid compositions (X), and time (t). Structural fabrics are represented in rocks by features such as foliations and shear zones developed at the mm to km scale. In ideal cases, the P-T-X history of a given structural fabric can be constrained using stable isotope, cation exchange, and/or mineral equilibria thermobarometry (Essene 1989). The timing of structural fabric development can be assessed qualitatively using geologic field observations or quantitatively using isotope-based geochronology. High-precision geochronology of the thermal and fluid flow histories associated with structural fabric development can answer fundamental geologic questions including (1) when hydrothermal fluids transported and deposited ore minerals, ...

  6. Qualitative Investigation of Some Locally Produced Printed Fabrics ...

    African Journals Online (AJOL)

    The results obtained showed that the locally produced fabrics exhibited comparably better end – use performance characteristics in terms of fabric weight per square meter, fabric flammability, and linear density. While the foreign fabrics are better in terms of Crease recovery, fabric handle, fabric sett, fabric shrinkage, and ...

  7. Fabrication of fiber optic long period gratings operating at the phase matching turning point using an amplitude mask

    Science.gov (United States)

    Hromadka, J.; Correia, R.; Korposh, S.

    2016-05-01

    A fast method for the fabrication of the long period gratings (LPG) optical fibres operating at or near the phase matching turning point (PMTP) with the period of 109.0, 109.5 and 110.0 μm based on an amplitude mask writing system is described. The proposed system allows fabricating 3 cm long LPG sensors operating at PMPT within 20 min that is approximately 8 times faster than point-by-point approach. The reproducibility of the fabrication process was thoroughly studied. The response of the fabricated LPGs to the external change of the refractive index was investigated using water and methanol.

  8. Fabricating nuclear components

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    Activities of the Nuclear Engineering Division of Vickers Ltd., particularly fabrication of long slim tubular components for power reactors and the construction of irradiation loops and rigs, are outlined. The processes include hydraulic forming for fabrication of various types of tubes and outer cases of fuel transfer buckets, various specialised welding operations including some applications of the TIG process, and induction brazing of specialised assemblies. (U.K.)

  9. Design and characterization of ultra-stretchable monolithic silicon fabric

    KAUST Repository

    Rojas, Jhonathan Prieto

    2014-10-13

    Stretchable electronic systems can play instrumental role for reconfigurable macro-electronics such as distributed sensor networks for wearable and bio-integrated electronics. Typically, polymer composite based materials and its deterministic design as interconnects are used to achieve such systems. Nonetheless, non-polymeric inorganic silicon is the predominant material for 90% of electronics. Therefore, we report the design and fabrication of an all silicon based network of hexagonal islands connected through spiral springs to form an ultra-stretchable arrangement for complete compliance to highly asymmetric shapes. Several design parameters are considered and their validation is carried out through finite element analysis. The fabrication process is based on conventional microfabrication techniques and the measured stretchability is more than 1000% for single spirals and area expansions as high as 30 folds in arrays. The reported method can provide ultra-stretchable and adaptable electronic systems for distributed network of high-performance macro-electronics especially useful for wearable electronics and bio-integrated devices.

  10. Design and characterization of ultra-stretchable monolithic silicon fabric

    KAUST Repository

    Rojas, Jhonathan Prieto; Carreno, Armando Arpys Arevalo; Foulds, I. G.; Hussain, Muhammad Mustafa

    2014-01-01

    Stretchable electronic systems can play instrumental role for reconfigurable macro-electronics such as distributed sensor networks for wearable and bio-integrated electronics. Typically, polymer composite based materials and its deterministic design as interconnects are used to achieve such systems. Nonetheless, non-polymeric inorganic silicon is the predominant material for 90% of electronics. Therefore, we report the design and fabrication of an all silicon based network of hexagonal islands connected through spiral springs to form an ultra-stretchable arrangement for complete compliance to highly asymmetric shapes. Several design parameters are considered and their validation is carried out through finite element analysis. The fabrication process is based on conventional microfabrication techniques and the measured stretchability is more than 1000% for single spirals and area expansions as high as 30 folds in arrays. The reported method can provide ultra-stretchable and adaptable electronic systems for distributed network of high-performance macro-electronics especially useful for wearable electronics and bio-integrated devices.

  11. DRAPING SIMULATION OF WOVEN FABRICS

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, William [General Motors LLC; Jin, Xiaoshi [ESI Group NA; Zhu, Jiang [Optimal CAE; Wathen, Terrence [General Motors LLC; Doroudian2, Mark [ESI Group NA; Aitharaju, Venkat [General Motors LLC

    2016-09-07

    Woven fabric composites are extensively used in molding complex geometrical shapes due to their high conformability compared to other fabrics. Preforming is an important step in the overall process, where the two-dimensional fabric is draped to become the three-dimensional shape of the part prior to resin injection. During preforming, the orientation of the yarns may change significantly compared to the initial orientations. Accurate prediction of the yarn orientations after molding is important for evaluating the structural performance of the final part. This paper presents a systematic investigation of the angle changes during the preform operation for carbon fiber twill and satin weave fabrics. Preforming experiments were conducted using a truncated pyramid mold geometry designed and fabricated at the General Motors Research Laboratories. Predicted results for the yarn orientations were compared with experimental results and good agreement was observed

  12. Advanced Silicone-based Coatings for Flexible Fabric Applications, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Silicone coatings are the system of choice for inflatable fabrics used in several space, military, and consumer applications, including airbags, parachutes, rafts,...

  13. Automated fuel fabrication- a vision comes true

    International Nuclear Information System (INIS)

    Hemantha Rao, G.V.S.; Prakash, M.S.; Setty, C.R.P.; Gupta, U.C.

    1997-01-01

    When New Uranium Fuel Assembly Project at Nuclear Fuel Complex (NFC) begins production, its operator will have equipment provided with intramachine handling systems working automatically by pressing a single button. Additionally simple low cost inter machine handling systems will further help in critical areas. All these inter and intra machine handling systems will result in improved reliability, productivity and quality. The fault diagnostics, mimics and real time data acquisition systems make the plant more operator friendly. The paper deals with the experience starting from layout, selection of product carriers, different handling systems, the latest technology and the integration of which made the vision on automation in fuel fabrication come true. (author)

  14. Fabricating a multi-level barrier-integrated microfluidic device using grey-scale photolithography

    International Nuclear Information System (INIS)

    Nam, Yoonkwang; Kim, Minseok; Kim, Taesung

    2013-01-01

    Most polymer-replica-based microfluidic devices are mainly fabricated by using standard soft-lithography technology so that multi-level masters (MLMs) require multiple spin-coatings, mask alignments, exposures, developments, and bakings. In this paper, we describe a simple method for fabricating MLMs for planar microfluidic channels with multi-level barriers (MLBs). A single photomask is necessary for standard photolithography technology to create a polydimethylsiloxane grey-scale photomask (PGSP), which adjusts the total amount of UV absorption in a negative-tone photoresist via a wide range of dye concentrations. Since the PGSP in turn adjusts the degree of cross-linking of the photoresist, this method enables the fabrication of MLMs for an MLB-integrated microfluidic device. Since the PGSP-based soft-lithography technology provides a simple but powerful fabrication method for MLBs in a microfluidic device, we believe that the fabrication method can be widely used for micro total analysis systems that benefit from MLBs. We demonstrate an MLB-integrated microfluidic device that can separate microparticles. (paper)

  15. Rapid and low-cost fabrication of polystyrene-based molds for PDMS microfluidic devices using a CO2 laser

    KAUST Repository

    Li, Huawei; Fan, Yiqiang; Foulds, Ian G.

    2011-01-01

    In this article, we described a rapid and low-cost method to fabricate polystyrene molds for PDMS microfluidic devices using a CO2 laser system. It takes only several minutes to fabricate the polystyrene mold with bump pattern on top of it using a CO2 laser system. The bump pattern can be easily transferred to PDMS and fabricate microchannles as deep as 3μm on PDMS. © (2012) Trans Tech Publications, Switzerland.

  16. Rapid and low-cost fabrication of polystyrene-based molds for PDMS microfluidic devices using a CO2 laser

    KAUST Repository

    Li, Huawei

    2011-11-01

    In this article, we described a rapid and low-cost method to fabricate polystyrene molds for PDMS microfluidic devices using a CO2 laser system. It takes only several minutes to fabricate the polystyrene mold with bump pattern on top of it using a CO2 laser system. The bump pattern can be easily transferred to PDMS and fabricate microchannles as deep as 3μm on PDMS. © (2012) Trans Tech Publications, Switzerland.

  17. Preparation of activated carbon fabrics from cotton fabric precursor

    Science.gov (United States)

    Salehi, R.; Dadashian, F.; Abedi, M.

    2017-10-01

    The preparation of activated carbon fabrics (ACFs) from cotton fabric was performed by chemical activation with phosphoric acid (H3PO4). The operation conditions for obtaining the ACFs with the highest the adsorption capacity and process yield, proposed. Optimized conditions were: impregnation ratio of 2, the rate of temperature rising of 7.5 °C min-1, the activation temperature of 500 °C and the activation time of 30 min. The ACFs produced under optimized conditions was characterized by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX). The surface area and pore volume of carbon nanostructures was characterized by BET nitrogen adsorption isotherm at 77 °K. The pore size distribution calculated from the desorption branch according to BJH method. The iodine number of the prepared ACFs was determined by titration at 30 °C based on the ASTM D4607-94. The results showed the improvement of porous structure, fabric shape, surface area (690 m2/g), total pore volume (0.3216 cm3/g), and well-preserved fibers integrity.

  18. Micro-fabricated all optical pressure sensors

    DEFF Research Database (Denmark)

    Havreland, Andreas Spandet; Petersen, Søren Dahl; Østergaard, Christian

    2017-01-01

    Optical pressure sensors can operate in certain harsh application areas where the electrical pressure sensors cannot. However, the sensitivity is often not as good for the optical sensors. This work presents an all optical pressure sensor, which is fabricated by micro fabrication techniques, where...... the sensitivity can be tuned in the fabrication process. The developed sensor design, simplifies the fabrication process leading to a lower fabrication cost, which can make the all optical pressure sensors more competitive towards their electrical counterpart. The sensor has shown promising results and a linear...... pressure response has been measured with a sensitivity of 0.6nm/bar....

  19. Fabrication of polymeric nano-batteries array using anodic aluminum oxide templates.

    Science.gov (United States)

    Zhao, Qiang; Cui, Xiaoli; Chen, Ling; Liu, Ling; Sun, Zhenkun; Jiang, Zhiyu

    2009-02-01

    Rechargeable nano-batteries were fabricated in the array pores of anodic aluminum oxide (AAO) template, combining template method and electrochemical method. The battery consisted of electropolymerized PPy electrode, porous TiO2 separator, and chemically polymerized PAn electrode was fabricated in the array pores of two-step anodizing aluminum oxide (AAO) membrane, based on three-step assembling method. It performs typical electrochemical battery behavior with good charge-discharge ability, and presents a capacity of 25 nAs. AFM results show the hexagonal array of nano-batteries' top side. The nano-battery may be a promising device for the development of Micro-Electro-Mechanical Systems (MEMS), and Nano-Electro-Mechanical Systems (NEMS).

  20. Lithography-free centimeter-long nanochannel fabrication method using an electrospun nanofiber array

    International Nuclear Information System (INIS)

    Park, Suk Hee; Shin, Hyun-Jun; Lee, Sangyoup; Kim, Yong-Hwan; Yang, Dong-Yol; Lee, Jong-Chul

    2012-01-01

    Novel cost-effective methods for polymeric and metallic nanochannel fabrication have been demonstrated using an electrospun nanofiber array. Like other electrospun nanofiber-based nanofabrication methods, our system also showed high throughput as well as cost-effective performances. Unlike other systems, however, our fabrication scheme provides a pseudo-parallel nanofiber array a few centimeters long at a speed of several tens of fibers per second based on our unique inclined-gap fiber collecting system. Pseudo-parallel nanofiber arrays were used either directly for the PDMS molding process or for the metal lift-off process followed by the SiO 2 deposition process to produce the nanochannel array. While the PDMS molding process was a simple fabrication based on one-step casting, the metal lift-off process followed by SiO 2 deposition allowed finetuning on height and width of nanogrooves down to subhundred nanometers from a few micrometers. Nanogrooves were covered either with cover glass or with PDMS slab and nanochannel connectivity was investigated with a fluorescent dye. Also, nanochannel arrays were used to investigate mobility and conformations of λ-DNA. (paper)