Application of deep learning in the identification of TAO

Science.gov (United States)

Wu, Cong; Jin, Jicheng

2018-03-01

Thyroid associated ophthalmopathy (TAO) is one of the most common orbital disease, it can be easily detected by the human eye in the late onset due to obvious changes in extraocular muscles. But in the early stage, it is not easy to be distinguish by doctors with eye because of subtle changes in extraocular muscles, so it is a good way to use the computer's ability to assist doctors to pre-diagnosis of TAO for follow-up treatment. In this paper, according to the routine diagnosis process of doctors, a comprehensive detection system network is proposed. The network consists of three different convolutional neural subnetwork, corresponding to three bitmaps of eye CT images .Finally, the output of three subnetwork are combined to generate final diagnostic result by the majority vote. Through the experiment, the detection system, whose recognition rata is 94.87%, has a good ability to identify the characteristics of TAO, can assist the doctor in the early diagnosis of TAO in a certain extent, so as to help early patients get timely treatment.

Teaching in the Tao.

Science.gov (United States)

Christie, Patrick

This book shares the philosophy that what a teacher learned through the martial arts form, Aikido, allowed him to look beyond aggressive acts without responding aggressively himself, viewing the student behind the angry behavior. The teacher notes that compassion works better than any form of discipline he has ever encountered in education. Tao,…

The TAO Accelerator Simulation Program

CERN Document Server

Sagan, David

2005-01-01

A new accelerator design and analysis simulation environment based on the BMAD relativistic charged particle dynamics library is in development at Cornell University. Called TAO (Tool for Accelerator Optimization), it is a machine independent program that implements the essential ingredients needed to solve simulation problems. This includes the ability to: 1. Design lattices subject to constraints, 2. Simulate errors and changes in machine parameters, and 3. Simulate machine commissioning including simulating data measurement and correction. TAO is designed to be easily customizable so that extending it to solve new and different problems is straight forward. The capability to simultaneously model multiple accelerator lattices, both linacs and storage rings, and injection from one lattice to another allows for the design and commissioning of large multi stage accelerators. It can also simultaneously model multiple configurations of a single lattice. Single particle, particle beam and macroparticle tracking i...

Pressure-induced amorphization of La1/3TaO3

International Nuclear Information System (INIS)

Noked, O.; Melchior, A.; Shuker, R.; Livneh, T.; Steininger, R.; Kennedy, B.J.; Sterer, E.

2013-01-01

La 1/3 TaO 3 , an A-site cation deficient perovskite, has been studied under pressure by synchrotron X-ray powder diffraction and Raman spectroscopy. It undergoes irreversible pressure induced amorphization at P=18.5 GPa. An almost linear unit cell volume decrease vs. pressure is observed from ambient pressure up to the phase transition. The Raman spectroscopy also shows amorphization at the same pressure, with positive shifts of all modes as a function of pressure. The pressure dependence of the E g and A 1g Raman modes arising from the octahedral oxygen network is discussed. - Graphical abstract: La 1/3 Tao 3 exhibits linear pressure–volume relation until irreversible pressure induced amorphization at 18.5 Gpa. - Highlights: • La 1/3 TaO 3 has been studied under pressure by synchrotron XRD and Raman spectroscopy. • La 1/3 TaO 3 undergoes irreversible pressure induced amorphization around 18.5 GPa. • The transition is manifested in both XRD and Raman measurements. • A linear P–V relation is observed from ambient pressure up to the phase transition

Improvements to TAO Ocean Observations as a Result of Refresh Technology

Science.gov (United States)

Grissom, K.; Petraitis, D. C.; Pounder, D.

2016-02-01

The Tropical Atmosphere Ocean (TAO) array has been a major observational component of El Nino Southern Oscillation (ENSO) and climate prediction research since its completion in 1994 by NOAA's Pacific Marine Environmental Laboratory (PMEL). In 2005 operational responsibility and control of the TAO array was transitioned from PMEL to the National Data Buoy Center (NDBC). As part of the transition, a project for TAO Technology Refresh was developed to address equipment obsolescence and the need for higher data throughput in real-time. Completed in 2014, the "TAO Refresh" array has met the requirements of the NOAA transition plan and added new capabilities and value. These new capabilities include a reduced latency of data and increased real-time resolution from one observation per sensor each day to 144+ observations per sensor each day. Also, improvements in NDBC data management practices resulted in the development of a new TAO Automated Statistical Quality-control (TASQ) system that provides a real-time automated quality-control method based upon 20 years of historical data. In addition, an active method for gathering actionable evidence and combating vandalism was achieved through the installation of cameras on TAO buoys. With these enhanced capabilities, the TAO Refresh array is better positioned to support timely analyses of the diurnal cycle and high frequency weather phenomena that affect climate. An added benefit of the Refresh technology is the reduced sampling error due to the temporal averaging. For example, during a recent week long vandalism event at a Refresh buoy we have found an average error of 0.24°C (±0.17) in the subsurface temperature daily average, with the maximum error of 0.67°C. Historically, due to the limitations of real-time communications, these errors were masked within the daily average. However, with today's satellite system we can retrieve the full-resolution time series in real-time and improve the quality of our data.

TAO-2/SPARTE, a language-enhanced computer aided teleoperation system

International Nuclear Information System (INIS)

Gravez, P.; Fournier, R.

1991-01-01

TAO-2 is a computer system designed by CEA/DTA/UR for the remote control of nuclear servicing servomanipulators. It results from several years of research which have led to the current availability of an industrial product featuring highly advanced performances. For undersea applications, a development has also been carried out with CYBERNETIX for controlling the new hydraulic arm built by this company. An integral element of TAO-2 is the SPARTE language which deals with off-line task programming and focuses on combined manual, automatic and mixed control modes. Additionally, it takes into account the on-line part of the human operator relative to adjustment, monitoring and incident recovery. Other promising features are hybrid control specification, mechanisms for the management of external events and 'learning by touching' capabilities. The present paper describes the basic principles of TAO-2. It first recalls the fundamentals of Computer Aided Teleoperation (CAT). The functional and hardware architectures which implement the TAO-2 CAT concepts are then outlined. The next parts emphasize the original characteristics of the SPARTE control and programming language. The paper ends with a brief presentation of our approach for CAT symbolic control

Tool Measures Depths of Defects on a Case Tang Joint

Science.gov (United States)

Ream, M. Bryan; Montgomery, Ronald B.; Mecham, Brent A.; Keirstead, Bums W.

2005-01-01

A special-purpose tool has been developed for measuring the depths of defects on an O-ring seal surface. The surface lies in a specially shaped ringlike fitting, called a capture feature tang, located on an end of a cylindrical segment of a case that contains a solid-fuel booster rocket motor for launching a space shuttle. The capture feature tang is a part of a tang-and-clevis, O-ring joint between the case segment and a similar, adjacent cylindrical case segment. When the segments are joined, the tang makes an interference fit with the clevis and squeezes the O-ring at the side of the gap.

An experimental study in treatment for endometriosis with Xiao Chaihu Tang in rats

International Nuclear Information System (INIS)

Pan Li; Zheng Hui

2006-01-01

To explore the mechanism of Xiao Chaihu Tang in the treatment for endometriosis in rats,the rat model of endometriosis was established and were treated with Xiao Chaihu Tang , Danazol and Xiao Chaihu Tang plus Danazol for 4 weeks, respectively. Cyclooxygenase-2(COX- 2) expression in each group of endometrium and endometriotic tissue was observed by immuno- histochemistry method. The results showed that the expression of COX-2 in the endometriotic tissue was lower than that in endometrium in Xiao Chaihu Tang group and Xiao Chaihu Tang plus Danazol group, while Danazol group and control group were the opposite to Xiao Chaihu Tang group. The mechanism of Xiao Chaihu Tang in the treatment for endometriosis may be to decrease the COX-2 expression and reduce the formation of prostaglandins. (authors)

Os mentores intelectuais do confucionismo, do taoísmo e do hinduísmo na perspectiva weberiana

Directory of Open Access Journals (Sweden)

Arilson Silva de Oliveira

2009-05-01

Full Text Available Resumo Analisaremos os literati confucionistas e taoístas (intelectuais chineses e os mestres brahmanas (intelectuais indianos, apresentados por Max Weber, no intuito de apreendermos as imagens de mundo religiosas nos "jardins intelectuais e encantados" da China e da Índia. Para tanto, temos como base as duas primeiras monografias que fazem parte da obra Gesammelte Aufsätse zur Religionssoziologie (Ensaios sobre sociologia da religião a propósito das religiões chinesas e indianas, as quais foram as primeiras a serem lançadas na série de sociologia comparativa das religiões mundiais de Weber. Verificamos que os intelectuais chineses contribuem para a preservação e continuidade de sua civilização, fortalecendo suas alianças com o Estado, enquanto os intelectuais indianos, na condição de agentes puramente religiosos, participam significativamente da integração cultural de seu país, preservando sua própria autonomia social. Palavras-chave: Confucionismo; Taoísmo; Hinduísmo; Intelectuais; Max Weber.Abstract This article analyzes the Confucian and Taoist literati (Chinese intellectuals and Brahmin masters (Indian intellectuals presented by Max Weber, in order to apprehend religious world images in the “enchanted intellectual gardens” of China and India. For such, the first two monographs which are part of the work entitled Gesammelte Aufsätse zur Religionssoziologie (Essays on the sociology of religion are considered in what concerns the Chinese and Indian religions, which were the first to be published in Weber’s world religions comparative sociology series. It was verified that Chinese intellectuals contribute to the preservation and continuity of their civilization, strengthening their alliances with the State, whereas Indian intellectuals, as purely religious agents, significantly take part in the process of the country’s cultural integration, preserving their own social autonomy. Key words: Confucianism; Taoism

E-commerce business in the Chinese Market - A Case Study of Tao Bao

OpenAIRE

Zhang, Qian

2012-01-01

Abstract E-commerce in China has become a fast developing business in recent years. Many e-commerce companies have been set up to survive and benefit from the profitable business. Tao Bao, established in 2003, is the one of leading companies in e-commerce business. In the past few years, Tao Bao has become the favorite of the majority of customers in China and grown quickly. The purpose of the study was to make a marketing analysis of Tao Bao and enable the company to get better grow...

Farris-Tang retractor in optic nerve sheath decompression surgery.

Science.gov (United States)

Spiegel, Jennifer A; Sokol, Jason A; Whittaker, Thomas J; Bernard, Benjamin; Farris, Bradley K

2016-01-01

Our purpose is to introduce the use of the Farris-Tang retractor in optic nerve sheath decompression surgery. The procedure of optic nerve sheath fenestration was reviewed at our tertiary care teaching hospital, including the use of the Farris-Tang retractor. Pseudotumor cerebri is a syndrome of increased intracranial pressure without a clear cause. Surgical treatment can be effective in cases in which medical therapy has failed and disc swelling with visual field loss progresses. Optic nerve sheath decompression surgery (ONDS) involves cutting slits or windows in the optic nerve sheath to allow cerebrospinal fluid to escape, reducing the pressure around the optic nerve. We introduce the Farris-Tang retractor, a retractor that allows for excellent visualization of the optic nerve sheath during this surgery, facilitating the fenestration of the sheath and visualization of the subsequent cerebrospinal fluid egress. Utilizing a medial conjunctival approach, the Farris-Tang retractor allows for easy retraction of the medial orbital tissue and reduces the incidence of orbital fat protrusion through Tenon's capsule. The Farris-Tang retractor allows safe, easy, and effective access to the optic nerve with good visualization in optic nerve sheath decompression surgery. This, in turn, allows for greater surgical efficiency and positive patient outcomes.

Miljøforholdene i Tange Sø og Gudenåen

DEFF Research Database (Denmark)

Nielsen, K.; Jensen, J. P.; Skriver, J.

FORORD: Denne rapport er udarbejdet af Danmarks Miljøundersøgelser i forbindelse med høring om Tange Sø arrangeret af Viborg Amt i september 1998. Rapportens formål er at belyse de miljømæssige konsekvenser af syv fremkomne løsningsforslag til forbedring af passageforholdene ved Tangeværket......-20 betød, at ca. 13 km af Gudenåen blev omdannet til Tange Sø. Tange Sø blev anlagt der, hvor Gudenåens fald var størst. Anlæggelsen af Tange Sø medførte store fysiske ændringer i Gudenåen, idet de mest strømfyldte lokaliteter forsvandt. Dermed blev Gudenåens fysiske variation mindre, hvilket har påvirket...... plante- og dyreliv. Etableringen af Tangeværket bevirkede endvidere, at passageforholdene for fisk og smådyr blev stærkt forringet. Bygningen af fisketrappen har kun afhjulpet de dårlige passageforhold i begrænset omfang. Gennem de sidste 20 år er fosfortilførslen til Tange Sø formindsket fra ca. 100 til...

Eight new species of Cycloneuroterus Melika & Tang gallwasps from Taiwan and mainland China (Hymenoptera: Cynipidae: Cynipini).

Science.gov (United States)

Tang, Chang-Ti; Sinclair, Frazer; Hearn, Jack; Yang, Man-Miao; Stone, Graham N; Nicholls, James A; Schwéger, Szabina; Melika, George

2016-03-11

Eight new species of cynipid gallwasps, Cycloneuroterus abei Melika & Tang, C. ergei Tang & Melika, C. gilvus Melika & Tang, C. globosus Melika & Tang, C. jianwui Tang & Melika, C. lohsei Melika & Tang, C. tumiclavus Tang & Melika, C. uraianus Tang & Melika, from Taiwan and mainland China are described. Descriptions, diagnoses, biology, and host associations for the new species and a key to all Cycloneuroterus species are given. All taxa are supported by morphological and molecular data. Seven newly described species induce galls on Quercus subgenus Cyclobalanopsis, while one, C. uraianus, induces galls on Castanopsis. This is the first Cycloneuroterus species known to associate with Castanopsis.

Green-Tao theorem in function fields

OpenAIRE

Le, Thai Hoang

2009-01-01

We adapt the proof of the Green-Tao theorem on arithmetic progressions in primes to the setting of polynomials over a finite field, to show that for every $k$, the irreducible polynomials in $\\mathbf{F}_q[t]$ contain configurations of the form $\\{f+ Pg : \\d(P)

The tao of survival skills to keep you alive

CERN Document Server

Ayres, James Morgan

2013-01-01

The Tao of Survival focuses on real-world, core survival skills that can save your life anytime and anyplace, in any emergency situation. It delves into fundamental concepts that most survival books don't cover, including how to deal with fear, developing mind/body skills, and fully engaging your senses to be aware of your surroundings. James Morgan Ayres has worked as a consultant for various U.S. government agencies and private corporations, founded four companies, and lived and worked all over the world. He's written seven books, taught seminars on the tao of survival and related

Two cases of Chest Heating Sensation treated by Hwangryunhaedok-tang Herbal-Acupuncture

Directory of Open Access Journals (Sweden)

Gwon-Il Cho

2003-06-01

Full Text Available The purpose of this study is to evaluate the clinical effect of Hwangryunhaedok-tang Herbal-Acupuncture. Hwangryunhaedok-tang is used in all heating diseases. Chest Heating Sensation is a unique concept in Oriental Medicine. So we applied Hwangryunhaedok-tang Herbal-Acupuncture to treat the Chest Heating Sensation. We used DITI(Digital Infrared Thermographic Imaging to estimate the temperatures of chest surface for the outcome assessment. We came to know that the chest surface temperatures were all reduced in both cases after Herbal-Acupuncture treatment. The reduced average temperature was 1.5℃ in case 1 and 0.9℃ in case 2. The above result indicates that Hwangryunhaedok-tang Herbal-Acupuncture treatment has an effect on Chest Heating Sensation, thus continuous Hwangryunhaedok-tang Herbal-Acupuncture study will be needed for more clinical applications.

Race, Slavery, and the Re-evaluation of the T'ang Canon

OpenAIRE

Rutledge, Gregory E.

2014-01-01

In his article "Race, Slavery, and the Revaluation of the T'ang Canon" Gregory E. Rutledge re-evaluates—from the purview of African Diaspora literary studies—historiography that considers the place of East African slave lore in T'ang Dynasty fiction. Julie Wilensky's "The Magical Kunlun and 'Devil Slaves': Chinese Perceptions of Dark-skinned People and Africa before 1500" (2002), a revision of Chang Hsing-lang's "The Importation of Negro Slaves to China Under the T'ang Dynasty (A.D. 618-907)"...

L'étang de Dombes. Insertion dans le paysage agraire

Directory of Open Access Journals (Sweden)

BILLARD A.

1979-01-01

Full Text Available Les étangs constituent en Dombes centrale un élément original et un facteur de complexité du paysage agraire. Ils sont situés dans des dépressions au sol imperméable établies entre des collines glaciaires barrées par des digues d'argile et sont de forme irrégulière ; leur alimentation est à peu près exclusivement assurée par les eaux de pluie. Ces étangs, d'une superficie courante de 20 à 30 ha, sont soumis à un assolement pas toujours régulier qui fait alterner la production de poissons (évolage et la production de céréales ou de mais (assec. Constituant un niveau de base local, la nappe d'eau de l'étang en évolage limite les phénomènes d'érosion et assure un rôle d'équilibre. L'étang représente une forme d'adaptation aux conditions naturelles mais il est indissociable des formes d'habitat dispersé et des grandes parcelles de l'exploitation d'un seul tenant. L'origine des étangs remonte au Moyen-Age. Mais le rythme des constructions se serait accéléré à partir des 15ème et 16ème siècles. L'analyse du paysage agraire, Jointe aux données d'un manuscrit en date de 1704, suggère que le développement des étangs serait lié à un phénomène de concentration foncière qui a donné naissance aux grands domaines de la Dombes. Avec sa production de poisson réservé au propriétaire à l'exclusion des paysans, l'étang représentait dans une région, alors très pauvre, l'introduction de l'économie de marché.

Acute toxicity and genotoxicity study of fermented traditional herb formula Guibi-tang.

Science.gov (United States)

Park, Hwayong; Hwang, Youn-Hwan; Yang, Hye Jin; Kim, Hyun-Kyu; Song, Kyung Seuk; Ma, Jin Yeul

2014-10-28

Guibi-tang (Guipi-tang in Chinese and Kihi-to in Japanese) is a multi-herb traditional medicine commonly prescribed to treat psychoneurosis in East Asia. Although this medicine has been widely used, there is little available information on the safety and toxicity of Guibi-tang, especially on the fermented one. Guibi-tang, composed of 12 herbs, was fermented with bacteria and lyophilized. Single dose acute toxicity in rats was observed for 14 days after administration. Genetic toxicity of fermented Guibi-tang was evaluated on bacterial reverse mutation in Salmonella and Escherichia spp., chromosome aberrations in Chinese hamster ovary cells, and micronucleus formation in mice. Ingredients in FGBT were identified and quantified by high performance liquid chromatography-mass spectrometry. In acute oral toxicity study, behavior, clinical signs and body weight changes were normal observing in all experimental animals. No revertant colonies were found in any bacterial cultures examined. Morphological or numerical anomalies and significant increased number of aberrant metaphases were not observed. Micronucleus assay showed no significant increases in the frequency of inducing micronuclei in any dose examined. Decursinol, decursin, glycyrrhizin, and 6-gingerol in fermented Guibi-tang were identified and quantitated. As a whole, no acute and genotoxic effects were found in all the assays and parameters analyzed. Fermented Guibi-tang was recognized as safe and non-toxic, and therefore can be used for applications of traditional medicine in modern complementary and alternative therapeutics and health care. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Da-Chaihu-Tang alters the pharmacokinetics of nifedipine in rats and a treatment regimen to avoid this.

Science.gov (United States)

He, Ju-Xiu; Ohno, Kenji; Tang, Jun; Hattori, Masao; Tani, Tadato; Akao, Teruaki

2014-11-01

To investigate the influence of co-administrated Da-Chaihu-Tang (DCT; a traditional Chinese formulation) on the pharmacokinetics of nifedipine, as well as the safe optimal dosing interval to avoid the adverse interactions. A single dose of DCT was administered with nifedipine simultaneously, 2 h before, 30 min before or 30 min after nifedipine administration. Pharmacokinetics of nifedipine with or without DCT were compared. The influences of DCT on nifedipine intestinal mucosal and hepatic metabolism were studied by using rat in-vitro everted jejunal sac model and hepatic microsomes. A simultaneous co-administration of DCT significantly increased the area under concentration-time curve from time zero to infinity (AUC0-inf ) of nifedipine. In-vitro mechanism investigations revealed that DCT inhibited both the intestinal and the hepatic metabolism of nifedipine. Further study on the optimal dosing interval for nifedipine and DCT revealed that administration of DCT 30 min before or after nifedipine did not significantly change the AUC of nifedipine. The bioavailability of nifedipine is significantly increased by a simultaneous oral co-administration of DCT. This increase is caused by the inhibitory effect of DCT on both the intestinal mucosal and the hepatic metabolism of nifedipine. The dose interval between DCT and nifedipine needs to be set for over 30 min to avoid such drug-drug interactions. © 2014 Royal Pharmaceutical Society.

[Effects of three Wenyang Jianpi Tang on cell proliferation and apoptosis of nonalcoholic fatty liver cells].

Science.gov (United States)

Yang, Jia-Yao; Tao, Dong-Qing; Liu, Song; Zhang, Shu; Ma, Wei; Shi, Zhao-Hong

2017-04-01

To investigate the effects of Sijunzi Tang, Lizhong Tang and Fuzi Lizhong Tang on the cell proliferation and apoptosis of nonalcoholic fatty liver cells through the nonalcoholic fatty liver cell model established by inducing L02 cells with oleic acid. Different concentrations of oleic acid were added into L02 cells to induce the nonalcoholic fatty liver cell model. Oil red O staining was used to observe fatty droplets of fatty liver cells. Automatic biochemical analyzer was used to detect the levels of aspartic transaminase(AST), alanine aminotransferase(ALT), total cholesterol(TC), and triglyceride(TG) in the cell supernatants. There were five groups, namely normal group, model group, model and Sijunzi Tang group, model and Lizhong Tang group, and model and Fuzi Lizhong Tang group. The cell proliferation and apoptosis of the five groups were detected by MTT colorimetry test and flow cytometer. The expressions of PCNA, cleaved caspase-3, cleaved caspase-8, cleaved caspase-9, Bax and Bcl-2 proteins of the five groups were detected by Western blot. The oil red O staining results showed that the optimum concentration of oleic acid that was used to induce nonalcoholic fatty liver cell models was 80 mg•L-1. The levels of AST, ALT, TC and TG in the nonalcoholic fatty liver cell supernatants were higher than that in normal liver cell supernatants(PTang, Lizhong Tang and Fuzi Lizhong Tang could effectively promote the cell proliferation, and inhibit the cellular apoptosis of nonalcoholic fatty liver cells(PTang showed the best effect. Western blot results showed that Sijunzi Tang, Lizhong Tang and Fuzi Lizhong Tang could down-regulate the expressions of cleaved caspase-3, cleaved caspase-8, cleaved caspase-9 and Bax proteins, and up-regulate the expressions of PCNA and Bcl-2 proteins of nonalcoholic fatty liver cells. And Fuzi Lizhong Tang showed the best effect. In conclusion, all of Sijunzi Tang, Lizhong Tang and Fuzi Lizhong Tang could effectively promote the cell

On Tao and WorldThree%道与世界3①

Institute of Scientific and Technical Information of China (English)

吕乃基

2013-01-01

Tao is a core concept in traditional Chinese culture .Karl Popper's theory of Three Worlds ,well known in academia ,is closely related to Michael Polanyi’s theory on knowledge .Linking Tao and World Three provides a new viewpoint to understand Tao and enrich the understanding of World Three .%道，是中国传统文化的核心概念。波普尔的“三个世界”理论为学界所熟知，波兰尼关于知识的理论也与“三个世界”理论密切相关。将“道”与世界3联系起来，一方面为理解“道”提供一个新视角，另一方面也会丰富对世界3的认识。

Thermoluminescence authentication of T'ang and Han Dynasty pottery

International Nuclear Information System (INIS)

Price, D.M.

1997-01-01

More than 80 pieces of T'ang Dynasty and 40 Han Dynasty style ceramic wares have been analysed to determine the amount of thermoluminescence (TL) accumulated since the initial firing of the object and the level of the radiation flux which has created the TL. This paper presents a summary of the thermoluminescence analysis results. Approximately 60% of Han ceramics and 45% of the T'ang pottery authenticated have been shown to belong to periods other than that stylistically suggested. Items which have been found not to be of the anticipated antiquity generally fall into distinct age groups. Of the T'ang wares the most commonly copied item is found to be the horse and for the Han pieces, human figures and ewers/pots/vases represent the most frequently reproduced wares

Analisis Perbandingan Experiential Value antara Hong Tang dan Black Ball serta Hubungannya dengan Customer Satisfaction

Directory of Open Access Journals (Sweden)

Annetta Gunawan

2014-11-01

Full Text Available Black Ball and Hong Tang are two pioneers of Taiwanese dessert sellers in Jakarta. Both of them have product offering characteristics that are alike and have the same target market. From the initial observation, the researcher found that even though Black Ball has more outlets than Hong Tang, but Black Ball seems to be less popular than Hong Tang. The consumers’ preferences are varied, there are some consumers prefer Hong Tang, but there are also those who choose Black Ball, because of the food quality, the service provided, and also the experiences they get during the consumption process. Therefore, both Black Ball and Hong Tang have to consider about the experiential value to be offered to their customers, in order to increase their customer satisfaction, so that they can sustainably survive in the midst of challenging competition. The objectives of this research are to examine whether there is any difference of experiential value dimensions and customer satisfaction between Hong Tang and Black Ball and to examine the relationship between experiential value dimensions and customer satisfaction of Hong Tang and Black Ball. The result of this research concludes that there is no difference of all experiential value dimensions and customer satisfaction between Hong Tang and Black Ball and there is a strong and significant relationship between all experiential value dimensions and customer satisfaction of Hong Tang and Black Ball.

The cultural and ecological impacts of aboriginal tourism: a case study on Taiwan's Tao tribe.

Science.gov (United States)

Liu, Tzu-Ming; Lu, Dau-Jye

2014-01-01

We show that tourism activities severely impact the ecology of Orchid Island, its natural resources, and the culture of the Tao tribe. For example, highway widening, in response to the increased traffic volumes caused by tourism, required many Pandanus trees to be cut and removed, which has placed the coconut crabs in danger of extinction. To promote eco-tourism, observation trips to observe Elegant Scops owls and Birdwing butterflies have taken place, which has affected the breeding of these two protected species. The Elegant Scops owls- and Birdwing butterflies-related tourism activities also break the "evil spirits" taboo of the Tao people and have caused the disappearance of the specifications for using traditional natural resources, causing natural ecosystems to face the threat of excessive use. In addition to promoting and advocating aboriginal tourism of the Tao people on Orchid Island, the Taiwanese government should help the Tao people to develop a management model that combines traditional regulations and tourism activities.

Tang Xianzu and Shakespeare: Cultural Giants of East and West

Institute of Scientific and Technical Information of China (English)

Zou; Yuanjiang

2016-01-01

In the early years of the last century,Aoki Masaru,a Japanese drama history expert,for the first time compared Tang Xianzu and William Shakespeare from an international perspective.Tang was born in 1550,14years before Shakespeare,but they died in the same year,1616.Masaru notes in his History of Chinese Modern Drama:'They both were drama giants,born in the same historical period.

Two Early Gamma-ray Bursts Optical Afterglow Detections with TAOS Telescopes--GRB 071010B and GRB 071112C

International Nuclear Information System (INIS)

Huang, K. Y.; Wang, S. Y.; Urata, Y.

2009-01-01

We present on two early detections of GRB afterglows with the Taiwanese-American Occltation Sruvey (TAOS) telescopes. The robotic TAOS system has been devised so that the routine Kuiper Belt Object (KBO) survey is interrupted when a GRB alert is triggered. Our first detection, GRB 071010B was detected by TAOS 62 s after the burst and showed a weak early brightening during the observations. No significant correction with the prompt gamma-ray emission indicated that our optical emission detected is afterglow emission. The second detection of TAOS, GRB 071112C was detected 96 s after the burst, also showed a possible initial raising then followed a steep decay in the R-band light curve.

Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

OpenAIRE

Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

2015-01-01

Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial...

Cyclic Testing of the 6-Strand Tang and Modified Lim-Tsai Flexor Tendon Repair Techniques.

Science.gov (United States)

Kang, Gavrielle Hui-Ying; Wong, Yoke-Rung; Lim, Rebecca Qian-Ru; Loke, Austin Mun-Kitt; Tay, Shian-Chao

2018-03-01

In this study, we compared the Tang repair technique with the 6-strand modified Lim-Tsai repair technique under cyclic testing conditions. Twenty fresh-frozen porcine flexor tendons were randomized into 2 groups for repair with either the modified Lim-Tsai or the Tang technique using Supramid 4-0 core sutures and Ethilon 6-0 epitendinous running suture. The repaired tendons were subjected to 2 stage cyclic loading. The survival rate and gap formation at the repair site were recorded. Tendons repaired by the Tang technique achieved an 80% survival rate. None of the modified Lim-Tsai repairs survived. The mean gap formed at the end of 1000 cycles was 1.09 mm in the Tang repairs compared with 4.15 mm in the modified Lim-Tsai repairs. The Tang repair is biomechanically stronger than the modified Lim-Tsai repair under cyclic loading. The Tang repair technique may exhibit a higher tolerance for active mobilization after surgery with less propensity for gap formation. Copyright © 2018 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1997-present, Precipitation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Precipitation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1987-present, Salinity

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Salinity data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1977-present, Temperature

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Temperature data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1989-present, Evaporation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Evaporation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1989-present, Evaporation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Evaporation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1989-present, Evaporation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Evaporation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1980-present, Position

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Position data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1980-present, Position

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Position data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1980-present, Position

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Position data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1977-present, Wind

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Wind data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

[Metabonomics on toxicity reduction of Glycyrrhizae Radix et Rhizoma for Aconiti Lateralis Radix Preparata in Sini Tang].

Science.gov (United States)

Li, Ying; Fu, Chao-Mei; Peng, Wei; Li, Bo; Fu, Shu; Zhang, Hui-Min

2016-04-01

To analyze the endogenous metabolite changes in rat plasma after intervention by Sini Tang and Sini Tang without Glycyrrhizae Radix et Rhizoma based on GC-MS metabonomics technology, and study the toxicity reduction effect of Glycyrrhizae Radix et Rhizoma in Sini Tang on Aconiti Lateralis Radix Preparata. Eighteen SD rats were randomly divided into normal group, Sini Tang group and Sini Tang without Glycyrrhizae Radix et Rhizoma group on average. The rats in Sini Tang group and Sini Tang without Glycyrrhizae Radix et Rhizoma group were treated respectively with physic liquor by intragastric administration at the dose of 0.02 mL•g ⁻¹ (equivalent to 0.8 g•mL ⁻¹ crude drugs) once a day for 7 days. The rats in normal group were given with equal volume of saline solution. The plasma samples were collected from each rat 0.5 h after the last administration for GC-MS detection. The data was used for multivariate statistical analysis to obtain 14 potential metabolic markers(13 of them were identified). Then their relative content and metabolic pathways were analyzed. Compared with Sini Tang without Glycyrrhizae Radix et Rhizoma group, seven metabolic markers of were reduced in Sini Tang group. Analysis on physiological functions of these potential metabolic markers showed that the Glycyrrhizae Radix et Rhizoma in Sini Tang could reduce the toxicity of Aconiti Lateralis Radix Preparata by adjusting the glycolysis, lipid metabolism, citrate cycle and some amino acids metabolism. Copyright© by the Chinese Pharmaceutical Association.

77 FR 31036 - Notice of Availability of the Record of Decision for the Taos Resource Management Plan...

Science.gov (United States)

2012-05-24

... Mexico. FOR FURTHER INFORMATION CONTACT: Brad Higdon, Planning and Environmental Coordinator, Taos Field..., largely through the public participation provided under NEPA. The Draft RMP/ Environmental Impact...] Notice of Availability of the Record of Decision for the Taos Resource Management Plan/Environmental...

Geologic map and cross sections of the Embudo Fault Zone in the Southern Taos Valley, Taos County, New Mexico

Science.gov (United States)

Bauer, Paul W.; Kelson, Keith I.; Grauch, V.J.S.; Drenth, Benjamin J.; Johnson, Peggy S.; Aby, Scott B.; Felix, Brigitte

2016-01-01

The southern Taos Valley encompasses the physiographic and geologic transition zone between the Picuris Mountains and the San Luis Basin of the Rio Grande rift. The Embudo fault zone is the rift transfer structure that has accommodated the kinematic disparities between the San Luis Basin and the Española Basin during Neogene rift extension. The eastern terminus of the transfer zone coincides with the intersection of four major fault zones (Embudo, Sangre de Cristo, Los Cordovas, and Picuris-Pecos), resulting in an area of extreme geologic and hydrogeologic complexities in both the basin-fill deposits and the bedrock. Although sections of the Embudo fault zone are locally exposed in the bedrock of the Picuris Mountains and in the late Cenozoic sedimentary units along the top of the Picuris piedmont, the full proportions of the fault zone have remained elusive due to a pervasive cover of Quaternary surficial deposits. We combined insights derived from the latest geologic mapping of the area with deep borehole data and high-resolution aeromagnetic and gravity models to develop a detailed stratigraphic/structural model of the rift basin in the southern Taos Valley area. The four fault systems in the study area overlap in various ways in time and space. Our geologic model states that the Picuris-Pecos fault system exists in the basement rocks (Picuris formation and older units) of the rift, where it is progressively down dropped and offset to the west by each Embudo fault strand between the Picuris Mountains and the Rio Pueblo de Taos. In this model, the Miranda graben exists in the subsurface as a series of offset basement blocks between the Ponce de Leon neighborhood and the Rio Pueblo de Taos. In the study area, the Embudo faults are pervasive structures between the Picuris Mountains and the Rio Pueblo de Taos, affecting all geologic units that are older than the Quaternary surficial deposits. The Los Cordovas faults are thought to represent the late Tertiary to

Hoia ja keela / Mati Tang, Anne Oolup

Index Scriptorium Estoniae

Tang, Mati

2006-01-01

AS Tallinna Lennujaama plaan pikendada Kuressaare lennujaama lennurada elamukvartali suunas on leidnud vastuseisu maandumiskoridori alla jääva Marientali linnaosa elanikes. Arvamust avaldavad Kuressaare lennujaama juhataja M. Tang ja Kuressaare elanik A. Oolup

Blå biomasse – potentialer og udfordringer for opdræt af muslinger og tang

DEFF Research Database (Denmark)

Petersen, Jens Kjerulf; Bjerre, Anne-Belinda; Hasler, Berit

pdræt af muslinger og tang bygger på et fælles princip: Næringssalte i havet omsættes enten direkte gennem fotosyntese (tang) eller indirekte via filtrering af fytoplankton (muslinger) til bio-masse. Det kræver således ikke nogen form for fodring med dertil hørende miljøbelastning at dyrke...... muslinger og tang i havet og opdrættet kan øko-certificeres. Når muslingerne eller tangen bliver høstet, bringes næringssalte - der oprindeligt er tabt fra land - tilbage til land, og opdræt af muslinger og tang repræsenterer derfor et helt fundamentalt eksempel på cirkulær økonomi. Næringsrige kystvande......,5-14,6 mio. kr. årligt, mens en produktion på 100.000 tons muslinger, svarende til ca. 15.000 tons mel, vil levere økosystem tjenester for 91-293 mio. kr. årligt. Opdræt af tang i danske kystnære farvande er udfordret af store områder med for lav salthol-digheder og dårlige lysforhold. Opdræt af tang er et...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1988-2015, ADCP

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Acoustic Doppler Current Profiler (ADCP) water currents data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1988-2015, ADCP

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Acoustic Doppler Current Profiler (ADCP) water currents data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1988-2015, ADCP

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Acoustic Doppler Current Profiler (ADCP) water currents data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA...

Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells

Directory of Open Access Journals (Sweden)

Hiroe Go

2015-01-01

Full Text Available The present study was conducted to investigate the effect of Sagunja-tang on the lipid related disease in a rat model of menopausal hyperlipidemia and lipid accumulation in methyl-β-cyclodextrin-induced HepG2 cells. In in vivo study using menopausal hyperlipidemia rats, Sagunja-tang reduced retroperitoneal and perirenal fat, serum lipids, atherogenic index, cardiac risk factor, media thickness, and nonalcoholic steatohepatitis score, when compared to menopausal hyperlipidemia control rats. In HepG2 cells, Sagunja-tang significantly decreased the lipid accumulation, total cholesterol levels, and low-density/very-low-density lipoprotein levels. Moreover, Sagunja-tang reversed the methyl-β-cyclodextrin-induced decrease in the protein levels of critical molecule involved in cholesterol synthesis, sterol regulatory element binding protein-2, and low-density lipoprotein receptor and inhibited protein levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase as well as activity. Phosphorylation level of AMP-activated protein kinase was stimulated by Sagunja-tang. These results suggest that Sagunja-tang has effect on inhibiting hepatic lipid accumulation through regulation of cholesterol synthesis and AMPK activity in vitro. These observations support the idea that Sagunja-tang is bioavailable both in vivo and in vitro and could be developed as a preventive and therapeutic agent of hyperlipidemia in postmenopausal females.

Grandfather Tang Goes to High School

Science.gov (United States)

Johnson, Iris DeLoach

2006-01-01

This article describes how the children's literature book, Grandfather Tang's Story, which is commonly used in the elementary grades, may be used at the high school level to engage students in an exploration of area and perimeter which includes basic operations with square roots, ordering numbers (decimal approximations, and their exact…

Effects of Tang Mai Kang Capsule on Angioneurotic Lesions in Alloxan-Induced Diabetic Mice

Institute of Scientific and Technical Information of China (English)

李华; 王军; 高丽君; 郭永成

2004-01-01

The effects of Tang Mai Kang Capsule (糖脉康胶囊) on blood sugar level, gangrene of the tail-tip, pain threshold and learning and memory abilities were investigated in alloxan-induced diabetic mice. The results showed that Tang Mai Kang Capsule could significantly decrease blood sugar level and incidence rate of gangrene of the tail-tip, increase pain threshold, and strengthen learning and memory abilities, suggesting that Tang Mai Kang Capsule functions to decrease blood sugar level and improve the complicated angioneurotic lesions of diabetes.

The full-scale process and design changes for elimination of insulation edge separations and voids in tang flap area

Science.gov (United States)

Danforth, Richard A.

1991-01-01

Qualification of the full-scale process and design changes for elimination of redesigned solid rocket motor tang nitrile butadiene rubber insulation edge separations and voids was performed from 24 March to 3 December 1990. The objectives of this test were: to qualify design and process changes on flight hardware using a tie ply between the redesigned solid rocket motor steel case and the nitrile butadiene rubber insulation over the tang capture features; to qualify the use of methyl ethyl ketone in the tang flap region to reduce voids; and to determine if holes in the separator film reduce voids in the tang flap region. The tie ply is intended to aid insulation flow during the insulation cure process, and thus reduce or eliminate edge unbonds. Methyl ethyl ketone is intended to reduce voids in the tang flap area by providing better tacking characteristics. The perforated film was intended to provide possible vertical breathe paths to reduce voids in the tang area. Tang tie ply testing consisted of 270 deg of the tang circumference using a new layup method and 90 deg of the tang circumference using the current layup methods. Tie ply process success was defined as a reduction of insulation unbonds. Lack of any insulation edge unbonds on the tang area where the new process was used, and the presence of 17 unbonds with the current process, proves the test to be a success. Successful completion of this test has qualified the new processes.

Aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy treated with qing fei tang: two case reports.

Science.gov (United States)

Nozaki, Ichiro; Kato-Motozaki, Yuko; Ikeda, Tokuhei; Takahashi, Kazuya; Tagami, Atsuro; Ishida, Chiho; Komai, Kiyonobu

2015-03-26

Qing fei tang, which is used for various respiratory diseases, is useful for reducing relapse of aspiration pneumonia and bronchopneumonia in stroke, but the effect remains unknown in Parkinson's syndrome. We report two cases of Japanese patients with progressive supranuclear palsy and relapsing aspiration pneumonia and bronchopneumonia, which was successfully prevented by qing fei tang. Two Japanese men with progressive supranuclear palsy and receiving total enteral feeding (patient one (66-years-old) and patient two (76-years-old)) had experienced recurrent aspiration pneumonia and bronchopneumonia, which was unresponsive to conventional therapy. The respiratory infection developed twice at intervals of two months in patient one, and nine times at almost monthly intervals in patient two. Thereafter, they were given qing fei tang. After administration of qing fei tang, the respiratory infection reoccurred only once; after 5.5 months for patient one, and six months for patient two. Both of our patients clearly showed a reduced incidence of respiratory infection. Both of our patients clearly showed a reduced incidence of respiratory infection after the administration of qing fei tang. Qing fei tang could be useful for the prevention of recurrent aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy.

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1989-present, Wind Stress

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Wind Stress data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 2000-present, Buoyancy Flux

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Buoyancy Flux data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1989-present, Wind Stress

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Wind Stress data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1989-present, Evaporation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Evaporation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 2000-present, Buoyancy Flux

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Buoyancy Flux data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1977-present, Temperature

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Temperature data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1980-present, Heat Content

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Heat Content data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1980-present, Position

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Position data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 2000-present, Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Incoming Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 2000-present, Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Incoming Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 2000-present, Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Incoming Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

Edusemiotics:The Tao of Education

Institute of Scientific and Technical Information of China (English)

Inna Semetsky

2015-01-01

The paper presents a new field of inquiry, edusemiotics, at the intersection of theoretical semiotics and philosophy of education. A brief introduction to the distinguishing features of edusemiotics is offered as including process ontology, the logic of the included middle, the relational self, the 'untimely' and posthuman dimensions of experience, the embodied mind, and others. Edusemiotics comes out as partaking of the Chinese Tao in terms of being the way to wholeness and the integration of those dualistic opposites that continue to haunt Western education at the level of both theory and practice. Some implications of the edusemiotic perspective on ethics and epistemology for pedagogy, policy and teacher training are discussed.

The glass-like thermal conductivity in ZrO2-Dy3TaO7 ceramic for promising thermal barrier coating application

Science.gov (United States)

Wu, Peng; Hu, Ming Yu; Chong, Xiao Yu; Feng, Jing

2018-03-01

Using the solid-state reaction method, the (ZrO2)x-(Dy3TaO7)1-x (x = 0, 0.02, 0.04, 0.06, 0.08, and 0.1) ceramics are synthesized in this work. The identification of the crystal structures indicates that the (ZrO2)x-(Dy3TaO7)1-x ceramics belong to the orthorhombic system, and the space group is C2221 in spite of the value of x increasing to 0.1. The thermal conductivities of the (ZrO2)x-(Dy3TaO7)1-x ceramics range from 1.3 W/(m K) to 1.8 W/(m K), and this value is much lower than that of 7-8 YSZ (yttria-stabilized zirconia). Besides, the (ZrO2)x-(Dy3TaO7)1-x ceramics possess the glass-like thermal conductivity caused by intrinsic oxygen vacancies existing in the lattice of Dy3TaO7. Moreover, the results of thermal expansion rates demonstrate that the (ZrO2)x-(Dy3TaO7)1-x ceramics possess excellent high temperature phase stability, and the thermal expansion coefficients [(9.7-11) × 10-6 K-1] are comparable to that of 7-8 YSZ.

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1992-present, Sigma-Theta

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Sigma-Theta (Potential Density Anomaly) data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

THE TAOS PROJECT: RESULTS FROM SEVEN YEARS OF SURVEY DATA

Energy Technology Data Exchange (ETDEWEB)

Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Cook, K. H.; Lee, T. [Institute of Astronomy and Astrophysics, Academia Sinica. 11F of Astronomy-Mathematics Building, National Taiwan University. No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan (China); Granados, A. P. [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Apdo. Postal 106, Ensenada, Baja California 22800 (Mexico); Alcock, C.; Protopapas, P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Axelrod, T. [Steward Observatory, 933 North Cherry Avenue, Room No. 204, Tucson AZ 85721 (United States); Bianco, F. B. [Center for Cosmology and Particle Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Byun, Y.-I. [Department of Astronomy and University Observatory, Yonsei University, 134 Shinchon, Seoul 120-749 (Korea, Republic of); Chen, W. P. [Institute of Astronomy, National Central University, No. 300, Jhongda Road, Jhongli City, Taoyuan County 320, Taiwan (China); Coehlo, N. K. [Department of Statistics, University of California Berkeley, 367 Evans Hall, Berkeley, CA 94720 (United States); De Pater, I. [Department of Astronomy, University of California Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States); Kim, D.-W. [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany); Lissauer, J. J. [Space Science and Astrobiology Division 245-3, NASA Ames Research Center, Moffett Field, CA 94035 (United States); Marshall, S. L., E-mail: zwzhang@asiaa.sinica.edu.tw [Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, MS 29, Menlo Park, CA 94025 (United States); and others

2013-07-01

The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small ({approx}1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10{sup -3} events per star per year) and short in duration ({approx}200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically {approx}500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

The effect of Ga-mee-gwui-ryong-tang and Yuk-mee ji-hwang-tang Herbal-acupuncture on the growth of mice

Directory of Open Access Journals (Sweden)

Min-jung Kim

2006-12-01

Full Text Available Objectives : To investigate the effect of Ga-mee-Gwui-ryong-tang herbal acupuncture (GR-HA at GB39 and ST36 and the effect of Yuk-mee ji-hwang-tang herbal acupuncture (YM-HA at GB39 and KI10 on growth in mice. Methods : Mice were divided into 7 groups(n=10 ; saline-ST36, saline-GB39, saline-KI10, GR-HA-ST36 group treated with GR-HA at right ST36, GR-HA-GB39 group treated with GR-HA at right GB39, YM-HA-GB39 group treated with YM-HA at right GB39, YM-HA-KI10 group treated with YM-HA at right KI10. Saline-ST36 group, saline-GB39 group and saline-KI10 group were injected with saline at right ST36, GB39, KI10 respectively. Saline injection and HA were performed 3 times a week for 18 days. The length(total height, body length and tail length, weight and the protein efficiency ratio were measured as well as IGF-1 level in serum. Results : 1. GR-HA at GB39 and GR-HA at ST36 promoted growth in weight, tail length and total height but there was no statistical significance. 2. GR-HA at GB39 significantly promoted protein efficiency on the 14th day and GR-HA at ST36 on the 3rd day. 3. GR-HA at GB39 significantly increased serum IGF-1. GR-HA at ST36 increased IGF-1 slightly but with no statistical significance. 4. YM-HA at GB39 and YM-HA at KI10 promoted growth in weight, height, tail length and total height but there was no statistical relevance. 5. YM-HA at GB39 and YM-HA at KI10 significantly promoted protein efficiency on the 14th day. 6. YM-HA at GB39 and YM-HA at KI10 significantly increased serum IGF-1. Serum IGF-1 level of YM-HA-KI10 group was significantly higher than that of YM-HA-GB39 group. 7. Serum IGF-1 level of GR-HA-GB39 group was significantly higher than that of YM-HA-GB39 group. Conclusions : GR-HA and YM-HA both may promote growth. This study suggests that herbal acupuncture at GB39 is more effective with Gwui-ryong-tang than Yuk-mee ji-hwang-tang to promote growth. It also suggests that Yuk-mee ji-hwang-tang herbal acupuncture is more

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1988-2015, ADCP

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Acoustic Doppler Current Profiler (ADCP) water currents data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA...

[Clinical observation on idiopathic tinnitus treated with acupuncture, buzhong yiqi tang and cizhu wan].

Science.gov (United States)

Chen, Surong; Tan, Xuming; Fei, Lanbo; Xiang, Xiande

2018-04-12

To observe the differences in the clinical therapeutic effects on idiopathic tinnitus between the combined therapy with acupuncture and the modified formula of buzhong yiqi tang and cizhu wan and the simple administration of the modified formula of buzhong yiqi tang and cizhu wan . A total of 60 patients were randomized into a combined treatment group and an herbal medicine group, 30 cases in each one and 2 cases dropped out in the herbal medicine group. In the combined treatment group, acupuncture was given at the local acupoints for tinnitus, such as Yifeng (TE 17), penetrating needling technique from Ermen (TE 21) to Tinggong (SI 19) and Tinghui (GB 2) combined with the scalp acupuncture [the vertigo-auditory area, Baihui (GV 20)] and the oral administration of the modified formula of buzhong yiqi tang and cizhu wan . In the herbal medicine group, the oral administration of the modified formula of buzhong yiqi tang and cizhu wan was only applied. The treatment was given once a day in each group, 5 times a week for acupuncture and 7 times a week for the oral administration of herbal medicine. Totally, the treatment for 6 weeks was required in the two groups. Before and after treatment, the tinnitus severity score (TSS) and the score of tinnitus handicap inventory (THI) were observed and the clinical therapeutic effects were compared between the two groups. After treatment, the TSS and THI scores reduced as compared with those before treatment in the two groups (all P tang and cizhu wan achieve the superior therapeutic effects on idiopathic tinnitus as compared with the simple oral administration of the modified formula of buzhong yiqi tang and cizhu wan .

A partial entropic lattice Boltzmann MHD simulation of the Orszag-Tang vortex

Science.gov (United States)

Flint, Christopher; Vahala, George

2018-02-01

Karlin has introduced an analytically determined entropic lattice Boltzmann (LB) algorithm for Navier-Stokes turbulence. Here, this is partially extended to an LB model of magnetohydrodynamics, on using the vector distribution function approach of Dellar for the magnetic field (which is permitted to have field reversal). The partial entropic algorithm is benchmarked successfully against standard simulations of the Orszag-Tang vortex [Orszag, S.A.; Tang, C.M. J. Fluid Mech. 1979, 90 (1), 129-143].

[Analysis of chemical constituents of volatile components from Jia Ga Song Tang by GC-MS].

Science.gov (United States)

Tan, Qing-long; Xiong, Tian-qin; Liao, Jia-yi; Yang, Tao; Zhao, Yu-min; Lin, Xi; Zhang, Cui-xian

2014-10-01

To analyze the chemical components of volatile components from Jia Ga Song Tang. The volatile oils were extracted by water steam distillation. The chemical components of essential oil were analyzed by GC-MS and quantitatively determined by a normalization method. 103 components were separated and 87 components were identified in the volatile oil of Zingiberis Rhizoma. 58 components were separated and 38 components were identified in the volatile oil of Myristicae Semen. 49 components were separated and 38 components were identified in the volatile oil of Amomi Rotundus Fructus. 89 components were separated and 63 components were identified in the volatile oil of Jia Ga Song Tang. Eucalyptol, β-phellandrene and other terpenes were the main compounds in the volatile oil of Jia Ga Song Tang. Changes in the kinds and content of volatile components can provide evidences for scientific and rational compatibility for Jia Ga Song Tang.

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1991-present, Downgoing Shortwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Downgoing Shortwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1989-present, Wind Stress

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Wind Stress data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1997-present, Evaporation Minus Precipitation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Evaporation Minus Precipitation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1997-present, Evaporation Minus Precipitation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Evaporation Minus Precipitation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 1997-present, Evaporation Minus Precipitation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Evaporation Minus Precipitation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Quarterly, 2000-present, Net Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has quarterly Net Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Monthly, 1991-present, Net Shortwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has monthly Net Shortwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 2000-present, Net Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Net Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1992-present, Sea Surface Salinity

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Sea Surface Salinity data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1977-present, Sea Surface Temperature

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Sea Surface Temperature (SST) data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 2000-present, Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Incoming Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1987-present, Potential Density Anomaly

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National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily Potential Density Anomaly (sigma-theta) data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

Euiiyin-tang in the treatment of obesity: study protocol for a randomised controlled trial.

Science.gov (United States)

Cheon, Chunhoo; Jang, Soobin; Park, Jeong-Su; Ko, Youme; Kim, Doh Sun; Lee, Byung Hoon; Song, Hyun Jong; Song, Yun-Kyung; Jang, Bo-Hyoung; Shin, Yong-Cheol; Ko, Seong-Gyu

2017-06-21

Obesity is a public health concern in many countries due to its increasing prevalence. Euiiyin-tang is an herbal medicine formula often used as a clinical treatment for obesity. It acts to eliminate humidity and purify the blood, the causes of obesity identified by the theoretical framework of Korean medicine. The purpose of this study is to evaluate the efficacy and safety of Euiiyin-tang in treating obesity. This study is a randomised, double-blinded and placebo-controlled, multicentre trial. It has two parallel arms: the Euiiyin-tang group and the placebo group. A total of 160 obese adult women will be enrolled in the trial. The participants will be randomly divided at a 1:1 ratio at visit 2 (baseline). The participants will be administered Euiiyin-tang or placebo for 12 weeks. The primary endpoint is the change in weight occurring between baseline and post-treatment. The secondary outcomes include average weight reduction, changes in body fat, waist and hip circumferences, body mass index, and lipid profile, and the results of questionnaires such as the Korean version of Obesity-related Quality of Life, the Korean version of Eating Attitudes Test, the Social Readjustment Rating Scale, and the Stress Reaction Inventory. The present study will provide research methodologies for evaluating the efficacy and safety of Euiiyin-tang in patients with obesity. In addition, it will provide evidence of correlation between obesity and Sasang constitutional medicine. ClinicalTrials.gov, NCT01724099 . Registered on 2 November 2012.

Utilisation du phytoplancton pour estimer la production piscicole potentielle des étangs

Directory of Open Access Journals (Sweden)

BARBE J.

1999-07-01

Full Text Available Pour faciliter la gestion des étangs de pisciculture, il est nécessaire d'avoir un moyen pour estimer en cours de saison si l'objectif de production sera atteint, et éventuellement, intervenir sur la qualité du milieu. Les méthodes d'estimation et de prévision mentionnées dans la littérature ne sont pas applicables aux étangs de pisciculture, milieux fortement anthropisés. A partir de données (physico-chimie, plancton, production piscicole collectées sur 36 étangs en France, les auteurs proposent une méthode de prévision de la récolte piscicole à partir du phytoplancton (groupe prédominant et teneur en chlorophylle a. A l'usage, cette méthode s'est avérée satisfaisante pour prévoir des productions nettes jusqu'à plus de 500 kg/hectare.

Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin

OpenAIRE

Wang, Liye; Song, Yuehan; Li, Feng; Liu, Yan; Ma, Jie; Mao, Meng; Wu, Fengzhi; Wu, Ying; Li, Sinai; Guan, Binghe; Liu, Xiaolan

2014-01-01

Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medicine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. This suggests a possible relationship between Wen Dan Tang's pharmacological mechanism and the brain-gut axis. Based on this hypothesis, a sleep-deprived rat model was induced and Wen Dan Tang ...

Radionuclide concentrations in soils and produce from Cochiti, Jemez, Taos, and San Ildefonso Pueblo Gardens

International Nuclear Information System (INIS)

Fresquez, P.R.; Armstrong, D.R.; Salazar, J.G.

1995-05-01

Radionuclide ( 3 H, 90 Sr, 137 Cs, 238 Pu, 239 Pu, and total uranium) concentrations were determined in soils and produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens. All radionuclides in soils from Pueblo areas were within or just above regional statistical (natural and/or worldwide fallout) reference levels. Similarily, the average levels of radionuclides in produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens were not significantly different in produce collected from regional (background) locations. The effective (radiation) dose equivalent from consuming 352 lb of produce from Cochiti, Jemez, Taos, and San Ildefonso, after natural background has been subtracted, was 0.036 (±0.016), 0.072 (±0.051), 0.012 (±0.027), and 0.110 (±0.102) mrem/yr, respectively. The highest calculated dose, based on the mean + 2 std dev (95% confidence level), was 0.314 mrem/yr; this was <0.4% of the International Commission on Radiological Protection permissible dose limit for protecting members of the public

Lao Tse y el Tao te Ching

OpenAIRE

Román López, María Teresa

2008-01-01

En este artículo describiremos algunos de los aspectos más reveladores de la obra y del pensamiento de Lao tse que, en cierta medida, pueden ayudarnos a entender algunas de las razones que justifican la gran influencia que el taoísmo ha tenido en el mundo oriental antiguo y, en particular, en el pensamiento de ChinaIn this article we will describe some of the most developing aspects in the book and of the thought of Lao tse that, in certain measure, they can help us to understand some of th...

Isenção da ciência, neutralidade da análise

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Daniel Menezes Coelho

2012-01-01

Full Text Available O artigo discute as relações entre a psicanálise e a ciência, especialmente no que tange aos seus métodos de investigação e trabalho. Para isso, tomamos como objeto a noção de neutralidade, tal como podemos apreendê-la na clínica da psicanálise, para confrontá-la com o que chamamos de isenção no campo da ciência, que não quer dizer outra coisa que a neutralidade proposta lá. Veremos que, apesar da clara filiação da noção psicanalítica para com a noção vinda da ciência, a neutralidade clínica da psicanálise toma outro rumo, que se pode mesmo opor ao sentido do termo na ciência. Enquanto em ciência o termo quer significar um processo de purificação e de seleção, em psicanálise ele surge como a exigência de nada selecionar.

O VALOR DA MARCA COMO UM ATIVO INTANGÍVEL: UM ESTUDO DE CASO DA WEG S.A.

OpenAIRE

Teixeira, Juliana Pauli; Petri, Sergio Murilo; Marques, Tatiane de Oliveira

2012-01-01

ResumoEste estudo tem como objetivo identificar uma metodologia para mensuração de marcas, pois o valor de mercado de uma empresa não pode ser explicado apenas pelos seus ativos tangíveis, mas também pelos ativos intangíveis. Portanto, procurou-se elaborar um caso prático de mensuração para a marca baseado no método de fluxo de caixa descontado. Desta forma, utilizou-se da ferramenta denominada Scorecard da Marca para identificar e quantificar a influência exercida pela marca na geração de fl...

[Medical application of the art of supplication before the Tang dynasty].

Science.gov (United States)

Ding, Yuan; Ding, Jieyun; Zhang, Ruqing

2015-05-01

Ample materials on diseases treated with supplication were seen on excavated texts, medical works from ancient time, and religious works before the Tang dynasty (including Tang dynasty). Since the breaking up of witchcraft from medicine, there are still supplication applied in the treatment and prevention of diseases, including those of internal medicine, external medicine, women's and children's diseases, disease of the sense organs, and infections. There are dual reasons for this phenomena, one being the diseases caused by spirit and ghostss; and the other being certain effectiveness of this art on some diseases not cured by other regular treatments, hence, its acceptance by secular people.

Protective effect of Ssanghwa-tang fermented by Lactobacillus ...

African Journals Online (AJOL)

Ssanghwa-tang (SHT) is a traditional herbal medicine formula that has been used for the development of physical strength, relief of pain, and the reduction of fatigue. In this study, we fermented SHT with Lactobacillus fermentum (L. fermentum), Lactobacillus gasseri (L.gasseri), or Lactobacillus casei (L.casei) to investigate ...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 1997-present, Evaporation Minus Precipitation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Evaporation Minus Precipitation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

TAO/TRITON, RAMA, and PIRATA Buoys, 5-Day, 2000-present, Net Longwave Radiation

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has 5-day Net Longwave Radiation data from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/ ), RAMA (Indian Ocean,...

[Effect and mechanism of Mahuang Tang against influenza A/H1N1 virus in vitro].

Science.gov (United States)

Wei, Wen-Yang; Wan, Hai-Tong; Yu, Li; Lu, Yi-Yu; He, Yu

2018-02-01

To study the effect and underlying mechanism of Mahuang Tang against influenza A virus in vitro ， the influenza virus-infected Madin-Darby canine kidney(MDCK) cells were used as the carrier in this study to detect the median tissue culture-infective dose(TCID₅₀) of influenza A virus strains(A/PR8/34) on MDCK cells with cytopathic effect(CPE) assay. Blocking influenza virus invading host cells and anti-influenza virus biosynthesis were used as two different administration methods， and then the methyl thiazolyl tetrazolium(MTT) assay was utilized to determine the antiviral effective rate(ER)， median efficacious concentration(EC₅₀) and therapeutic index(TI) of Mahuang Tang. The quantitative Real-time polymerase chain reaction(RT-PCR) was used to measure virus load and the mRNA expression levels of TLR4， TLR7， MyD88 and TRAF6 in MDCK cells at 24， 48 h after the treatment. The experiment results indicated that TCID₅₀ of A/PR8/34 for MDCK cells was 1×10-4.32/mL. The EC₅₀ values of two different treatment methods were 4.92，1.59 g·L⁻¹ respectively， the TI values were 12.53， 38.78 respectively， and when the concentration of Mahuang Tang was 5.00 g·L⁻¹， ER values were 50.21%， 98.41% respectively， showing that Mahuang Tang can block influenza virus into the host cells and significantly inhibit their biosynthesis. Meanwhile， as compared with the virus group， the virus load was significantly inhibited in Mahuang Tang groups， and Mahuang Tang high and middle doses had the significant effect on decreasing the mRNA expression of TLR4， TLR7，MyD88 and TRAF6 at 24， 48 h after the treatment. It can be demonstrated that the mechanisms of Mahuang Tang against influenza A virus are related to the inhibition of influenza virus replication and the mRNA expression of correlative genes in TLR4 and TLR7 signaling pathways. Copyright© by the Chinese Pharmaceutical Association.

Rhein 8-O-β-D-Glucopyranoside Elicited the Purgative Action of Daiokanzoto (Da-Huang-Gan-Cao-Tang), Despite Dysbiosis by Ampicillin.

Science.gov (United States)

Takayama, Kento; Tabuchi, Norihiko; Fukunaga, Masahito; Okamura, Nobuyuki

2016-01-01

Sennoside A (SA), the main purgative constituent of Daiokanzoto (da-huang-gan-cao-tang; DKT), is generally regarded as a prodrug that is transformed into an active metabolite by β-glucosidase derived from Bifidobacterium spp. It has been suggested that antibiotics would promote dysbiosis, and thereby inhibit the purgative activity of DKT. In this study, ampicillin was administered to mice for 8 d, and the changes in the SA metabolism of SA alone and of DKT were investigated. The results showed that the SA metabolism of SA singly continued to be inhibited by ampicillin, but that of DKT was activated from day 3 under the same conditions. In order to investigate the mechanism of SA metabolism activated by DKT in the mice administered ampicillin, changes in the SA metabolism were observed in the presence of rhein 8-O-β-D-glucopyranoside (RG) in rhubarb and liquiritin in glycyrrhiza, both of which accelerated the SA metabolism. In fact, RG achieved an activation of SA metabolism similar to that by DKT. The purgative action of DKT, which was continued treatment of the ampicillin, was significantly greater than that by SA alone, and it was shown that RG was involved in this effect. We also analyzed changes in the intestinal microbiota before and after administration of ampicillin. No Bifidobacteria were detected throughout the treatment, but the population of Bacteroides was significantly increased after 3 d under the same conditions. Taken together, these results strongly suggested that the RG in DKT changed the function of Bacteroides and thereby allowed DKT to metabolize SA.

Maps of Relocation and Poems of Tang Dynasty Poets: Li Bai, Du Fu, and Han Yu

Directory of Open Access Journals (Sweden)

羅鳳珠、白璧玲、廖泫銘、范毅軍 、鄭錦全 Feng-Ju Lo,Pi-Ling Pai,Hsiung-Ming Liao,I-Chun Fan,Chin-Chuan Cheng

2014-04-01

Full Text Available Geographic environments affect literary contents and genre and thus, since ancient times, geographical area has been used to classify Chinese literature. In 1936 Liang Qichao was keenly aware of the relationship between literature and geography and brought up the idea of “literarygeography”. In 1979 Professor Chen Zhengxiang produced maps of birthplaces of Tang and Song poets to show the shift of Chinese cultural center from north to south. Furthermore, in the pastdecade, the attention to research in literary geography and geographical distribution of writersgradually increased. However, most studies focused on geographical distribution of birthplaces of writers and very few focused on the relationship between poets’ journey and the contents of their writings and their geographic environment. Meanwhile, geographic information system and aerialphotography have developed quickly and have become useful tools for the study of literary geography.Since then, the academic circles in Taiwan have built a solid foundation in this area. While Li Baiand Du Fu were called poetic immortal and poetic sage of the middle and end periods of the heydayof Tang Dynasty, respectively, Han Yu advocated the classical Chinese movement and becameone of the eight great authors of Tang and Song dynasties. Han Yu was also the best representative of Middle Tang poets. While the styles of these three poets differed from each other, they held key positions in the development and evolution of Tang poetry. Their footprints spread all over the countryand greatly affected later developments and contemporary of poetry. This project makes use of the digital Tang Dynasty maps by Tan Qixiang, Tang Dynasty transportation route maps by Yan Gengwang,aerial maps, the All Tang Poems, and chronicles of the poets to build the three poets’ relocation maps and study their poetic literature, language, geography, and interactions with others, in hopesof opening a new research direction

TAO/TRITON, RAMA, and PIRATA Buoys, Daily, 1977-present, 20C Isotherm Depth

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has daily 20C Isotherm Depth data (the depth at which the ocean temperature is 20C) from the TAO/TRITON (Pacific Ocean, https://www.pmel.noaa.gov/gtmba/...

[Influences of Confucianism, Taoism and Buddhism on Chinese Medical Formulas in Jin-Tang Dynasties].

Science.gov (United States)

Wu, Xiao-xiang

2006-04-01

In the Jin-Tang Dynasties, when Confucianism, Taoism and Buddhism contended, conflicted and well blent, forming a state of mingled thoughts of the three sects. It exerted profound influences on Chinese Medical Formulas and promoted the academic fashion of compiling books about medical formulas characterized by collecting various formulas especially the simple and proved recipes. This plays a role in the formation of the formulas used in the Jin-Tang Dynasties, featuring simplicity, convenience, cheapness, and effectiveness, different from those of other periods.

Effects of Tang Niao Ning decoction on ET-1, GMP-140 and TXB2 in diabetic rats

International Nuclear Information System (INIS)

Song Jumin; Wang Lifen; Liao Han; Wang Wei; Hua Weiguo

2003-01-01

To investigate the effects of Tang Niao Ning decoction on fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), endothelin (ET-1), platelet granule membrane protein (GMP-140), thromboxane B 2 (TXB 2 ), 6-keto-prostaglandin F 1α (6-keto-PGF 1α ), the selected female Wistar rats were modeled by streptozotocin (STZ) and high fat diets, and were randomly divided into two groups as Tang Niao Ning and model group, while the normal control group was set up. The Tang Niao Ning group started to supply decoctions after these rats had been fed one week with high fat diets. The rats were killed after six weeks. Above items were examed. The results showed that the model group displayed marked difference when the experiment finished compared with the normal group. The contents of fasting blood glucose and blood lipid were increased, accompanied with the phenomena of hoisting ET-1, enhancing GMP-140, increasing TXB 2 and droping 6-Keto-PGF 1α . After treatment in time with Tang Niao Ning decoction, all kinds of items were adjusted to normal level gradually. It suggested that the treatment with Tang Niao Ning decoction might decrease FBG and blood lipid. In some ways, the decoction could improve the signs of blood stasis. The regulation mechanisms of the decoction was characteristic of wholism through many channels

Case 3. "Jiang Tao v. Chengdu Branch, People's People's Bank of China": Opinion by the People's Court in Wuhou District, Chengdu, Sichuan Province

Science.gov (United States)

Chinese Education and Society, 2006

2006-01-01

This article presents the decision of the People's Court in Wuhou District, Chengdu, Sichuan Province on the Jiang Tao v. Chengdu Branch, People's People's Bank of China case. Jiang Tao, the plaintiff, claimed that the defendant Chengdu Branch placed an announcement in the "Chengdu Business Daily" to "recruit tellers for Chengdu…

Neutron activation analysis of the arovenance relation of tang tri-color glazed potteryies of huangye kiln and yaozhou kiln

International Nuclear Information System (INIS)

Li Guoxia; Zhao Weijuan; Gao Zhengyao; Xie Jianzhong; Guo Min

2006-01-01

The technique of neutron activation analysis (NAA) has been employed to measure the content of 29 kinds of elements in the Tang Tri-color glazed potteryies of Huangye kiln and Yaozhou kiln. Then a fuzzy cluster analysis has been conducted to the NAA data. The results indicate that the places of origin of raw materials of body samples in the Tang Tri-color glazed potteryies of Huangye kiln are very concentrated, and that the places of origin of raw materials of body and glaze samples are scattered the places of origin of raw materials of the body and glaze raw material cover that of the body raw material. The source of raw materials of samples in the Tang Tri-color glazed potteryies of Huangye kiln is obviously different from that of samples in the Tang Tri-color glazed potteryies of Yaozhou kiln. (authors)

An experimental study of mechanism in treatment for endometriosis with Xiao Chai Hu Tang in rats

International Nuclear Information System (INIS)

Zhang Hui; Zuo Liandong; Li Hongyi

2005-01-01

To explore the mechanism of Xiao Chai Hu Tang in treatment for endometriosis in rats, the rat model of endometriosis was established. Using immunohistochemistry method, Fas and Caspase-3 protein expression in endometrium and endometriotic tissue of each group were observed. The results showed that in the group treated with Xiao Chai Hu Tang, the protein expressions of Fas and Caspase-3 in endometriotic tissue were higher than those in endometrium, while in the control group, the result was just opposite. The difference was not obvious in the group treated with Danazol . The higher levels of the protein expression of Fas in endometriotic tissue may related to the pathogenesis of the endometriosis. The mechanism of Xiao Chai Hu Tang treatment may be partly to increase apoptosis in endometriotic tissue. (authors)

LOGÍSTICA REVERSA: um estudo na cadeia produtiva da linha branca

Directory of Open Access Journals (Sweden)

Gilson Scholl Pires

2017-01-01

Full Text Available O presente artigo faz referência à logística reversa, a qual se encontra dentro da nova demanda mundial que tange a ordem da sustentabilidade. A pesquisa foi apresentada de forma qualitativa e descritiva, com o objetivo de verificar como uma empresa de grande porte do segmento da linha branca trabalha a logística reversa de pós-consumo. Obteve-se dados que explanam como a logística reversa é um diferencial para a organização e como ela auxilia o processo logístico no fluxo inverso, no qual a mesma é efetiva no descarte correto e adequado dos produtos da linha branca.

A INFLUÊNCIA DA TECNOLOGIA E DA INTERNET NO MARKETING

Directory of Open Access Journals (Sweden)

Lúcia Cristina Vargas Machado

2014-09-01

Full Text Available O dinamismo do mundo globalizado vem exigindo grandes mudanças das organizações, sejam para aquelas que produzem bens tangíveis, sejam para as prestadoras de serviços. E dentro da observância das mudanças, pode-se considerar as revoluções vividas pela humanidade, considerando aquela que mais mudou o cenário mercadológico pela primeira vez que foi 1ª revolução industrial e, a outra, a revolução da informação. Neste contexto, o objetivo deste trabalho é demonstrar através da revisão de literatura, a significativa e importante transformação da informação para a área de marketing das organizações. A revolução da informação, tendo como suas precursoras e legítimas aliadas a tecnologia e a internet, respectivamente, fez com que surgisse um novo tipo de marketing: o marketing digital. Com este novo tipo de marketing, as organizações que estiverem mais presentes na internet, poderão obter uma maior vantagem competitiva e como consequência uma maior lucratividade

TAO-robust backpropagation learning algorithm.

Science.gov (United States)

Pernía-Espinoza, Alpha V; Ordieres-Meré, Joaquín B; Martínez-de-Pisón, Francisco J; González-Marcos, Ana

2005-03-01

In several fields, as industrial modelling, multilayer feedforward neural networks are often used as universal function approximations. These supervised neural networks are commonly trained by a traditional backpropagation learning format, which minimises the mean squared error (mse) of the training data. However, in the presence of corrupted data (outliers) this training scheme may produce wrong models. We combine the benefits of the non-linear regression model tau-estimates [introduced by Tabatabai, M. A. Argyros, I. K. Robust Estimation and testing for general nonlinear regression models. Applied Mathematics and Computation. 58 (1993) 85-101] with the backpropagation algorithm to produce the TAO-robust learning algorithm, in order to deal with the problems of modelling with outliers. The cost function of this approach has a bounded influence function given by the weighted average of two psi functions, one corresponding to a very robust estimate and the other to a highly efficient estimate. The advantages of the proposed algorithm are studied with an example.

TAO2000 V2 computer-assisted force feedback tele-manipulators used as maintenance and production tools at the AREVA NC-La Hague fuel recycling plant

International Nuclear Information System (INIS)

Geffard, Franck; Garrec, Philippe; Piolain, Gerard; Brudieu, Marie-Anne; Thro, Jean-Francois; Coudray, Alain; Lelann, Eric

2012-01-01

During a 15-year joint research program, French Atomic Energy Agency Interactive Robotics Laboratory (CEA LIST) and AREVA have developed several remote operation devices, also called tele-robots. Some of them are now commonly used for maintenance operations at the AREVA NC (Nuclear Cycle) La Hague reprocessing plant. Since the first maintenance operation in 2005, several other successful interventions have been realized using the industrial MA23/RX170 tele-manipulation system. Moreover, since 2010, the through-the-wall tele-robot named MT200 TAO based on the slave arm of the MSM MT200 (La Calhene TM ), has been evaluated in an active production cell at the AREVA NC La Hague fuel recycling plant. Although these evaluations are ongoing, the positive results obtained have led to an update and industrialization program. All these developments are based on the same generic control platform, called TAO2000 V2. TAO2000 V2 is the second release of the CEA LIST core software platform dedicated to computer aided force-feedback tele-operation (TAO is the French acronym for computer aided tele-operation). This paper presents all these developments resulting from the joint research program CEA LIST/AREVA. The TAO2000 V2 controller is first detailed, and then two maintenance operations using the industrial robot RX170 are presented: the removal of the nuclear fuel dissolver wheel rollers and the cleanup of the dissolver wheel inter-bucket spaces. Finally, the new MT200 TAO system and its evaluations at the AREVA NC La Hague facilities are discussed. (authors)

An internet-based intervention for adjustment disorder (TAO): study protocol for a randomized controlled trial.

Science.gov (United States)

Rachyla, Iryna; Pérez-Ara, Marian; Molés, Mar; Campos, Daniel; Mira, Adriana; Botella, Cristina; Quero, Soledad

2018-05-31

Adjustment Disorder (AjD) is a common and disabling mental health problem. The lack of research on this disorder has led to the absence of evidence-based interventions for its treatment. Moreover, because the available data indicate that a high percentage of people with mental illness are not treated, it is necessary to develop new ways to provide psychological assistance. The present study describes a Randomized Controlled Trial (RCT) aimed at assessing the effectiveness and acceptance of a linear internet-delivered cognitive-behavioral therapy (ICBT) intervention for AjD. A two-armed RCT was designed to compare an intervention group to a waiting list control group. Participants from the intervention group will receive TAO, an internet-based program for AjD composed of seven modules. TAO combines CBT and Positive Psychology strategies in order to provide patients with complete support, reducing their clinical symptoms and enhancing their capacity to overcome everyday adversity. Participants will also receive short weekly telephone support. Participants in the control group will be assessed before and after a seven-week waiting period, and then they will be offered the same intervention. Participants will be randomly assigned to one of the 2 groups. Measurements will be taken at five different moments: baseline, post-intervention, and three follow-up periods (3-, 6- and 12-month). BDI-II and BAI will be used as primary outcome measures. Secondary outcomes will be symptoms of AjD, posttraumatic growth, positive and negative affect, and quality of life. The development of ICBT programs like TAO responds to a need for evidence-based interventions that can reach most of the people who need them, reducing the burden and cost of mental disorders. More specifically, TAO targets AjD and will entail a step forward in the treatment of this prevalent but under-researched disorder. Finally, it should be noted that this is the first RCT focusing on an internet

Study of meterial distribution of Tang tricolor from Huangye kiln

International Nuclear Information System (INIS)

Dong Junling; Zhao Weijuan; Liu Guodong; Cheng Huansheng; Liao Yongmin; Zhang Songlin

2008-01-01

By using the proton induced X-ray enission (PIXE) method, the measurements of the oxide compound content have veen carried out for the selected 18 samples of Tang tricolor in Huangye kiln. For ascertaining the classification and origin relation of the samples the principal component analysis method was adopted, and the results indicate that the chemical compositions of Tang tricolor body with diggerent glaze colors are close, which shows that their raw material habitat distribution is quite concentrative. But the prescriptions of diffierent color glaze are different. The content of CoO is more than others in blue glaze; CuO is more than others in green glaze; Fe 2 O 3 is more than others in brown and yellow glaze; A1 2 O3 is less than others but SiO 2 is more in white glaze, which shows that glazers material origin is diffierent, but brown and yellow glaze are close and even the same in chemistry component. (authors)

Lao Tse y el Tao te Ching

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María Teresa Román López

2008-01-01

Full Text Available En este artículo describiremos algunos de los aspectos más reveladores de la obra y del pensamiento de Lao tse que, en cierta medida, pueden ayudarnos a entender algunas de las razones que justifican la gran influencia que el taoísmo ha tenido en el mundo oriental antiguo y, en particular, en el pensamiento de ChinaIn this article we will describe some of the most developing aspects in the book and of the thought of Lao tse that, in certain measure, they can help us to understand some of the reasons that justify the great influence that the Taoism has had in the old oriental world and, in particular, in the thought of China.

[Effect of Zhenwu Tang on regulating of "AVP-V2R-AQP2" pathway in NRK-52E cells].

Science.gov (United States)

Zhou, Xiao-Jie; Bao, Yu-Ting; Chen, Hong-Shu; Xuan, Ling; Chen, Xue-Ming; Zhang, Jie-Ying; Yang, Yuan-Xiao; Li, Chang-Yu

2018-02-01

This study was aimed to investigate the effect and mechanism of Zhenwu Tang on AVP-V2R-AQP2 pathway in NRK-52E cells in vitro . Forty eight male SD rats were randomly divided into eight groups with 6 animals in each group. Distilled water or 22.68 g·kg⁻¹·d⁻¹ Zhenwu Tang(calculated by raw drug dosage meter) was given by gavage. Blood samples were collected by cardiac puncture， and the medicated serum was centrifuged from the blood by 3 000 r·min⁻¹. NRK-52E cells were treated with different medicated serum or dDAVP. The condition of cell proliferation was detected by RTCA. The distribution of V2R and AQP2 in cells were detected by immunofluorescence. The expression of V2R， PKA and AQP2 were detected by Western blot and AQP2 mRNA level was detected by real-time PCR. Results showed that the level of AQP2 mRNA( P Tang medicated serum for 24 h were significantly higher than that of normal rat serum group. And the expression level of V2R， p-AQP2 and AQP2( P Tang medicated serum could increase the expression level of V2R， PKA and AQP2 which exist in AVP-V2R-AQP2 pathway in NRK-52E， and there is synergistic effect between Zhenwu Tang medicated serum and dDAVP. So the pathway of AVP-V2R-AQP2 may be one of the mechanism for which Zhenwu Tang regulate balance of water transportation. Copyright© by the Chinese Pharmaceutical Association.

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING TAO125W and MOORING_TAO125W_0 in the South Pacific Ocean from 2004-05-08 to 2012-05-25 (NODC Accession 0100076)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0100076 includes chemical, meteorological, physical and time series data collected from MOORING TAO125W and MOORING_TAO125W_0 in the South Pacific...

San Luis Valley - Taos Plateau Landscape-Level Cultural Heritage Values and Risk Assessment

Energy Technology Data Exchange (ETDEWEB)

Wescott, Konstance L. [Argonne National Lab. (ANL), Argonne, IL (United States); Abplanalp, Jennifer M. [Argonne National Lab. (ANL), Argonne, IL (United States); Brown, Jeff [Bureau of Land Management, Monte Vista, CO (United States); Cantwell, Brian [Argonne National Lab. (ANL), Argonne, IL (United States); Dicks, Merrill [Bureau of Land Management, Taos, NM (United States); Fredericks, Brian [Bureau of Land Management, Monte Vista, CO (United States); Krall, Angie [US Forest Service, Creede, CO (United States); Rollins, Katherine E. [Argonne National Lab. (ANL), Argonne, IL (United States); Sullivan, Robert [Argonne National Lab. (ANL), Argonne, IL (United States); Valdez, Arnie [Univ. of New Mexico, Albuquerque, NM (United States); Verhaaren, Bruce [Argonne National Lab. (ANL), Argonne, IL (United States); Vieira, Joseph [Bureau of Land Management, Monte Vista, CO (United States); Walston, Lee [Argonne National Lab. (ANL), Argonne, IL (United States); Zvolanek, Emily A. [Argonne National Lab. (ANL), Argonne, IL (United States)

2016-10-01

The San Luis Valley – Taos Plateau Landscape-Level Cultural Heritage Values and Risk Assessment (hereafter referred to as cultural assessment) is a BLM pilot project designed to see whether the Rapid Ecoregional Assessment (REA) framework (already established and implemented throughout many ecoregions in the West) can be applied to the cultural environment.

Acute Hepatitis Induced by Chinese Hepatoprotective Herb, Xiao-Chai-Hu-Tang

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Li-Ming Hsu

2006-02-01

Full Text Available Xiao-chai-hu-tang (syo-saiko-to in Japanese is a herbal remedy that has been widely used in China for treatment of respiratory, hepatobiliary, and gastrointestinal diseases, particularly among patients with chronic liver disease. However, its safety has recently been challenged. We, herein, report a Chinese patient with acute hepatitis induced by this herb. A 52-year-old woman presented with weakness, fatigue, and tea-colored urine after continual consumption of the decoction of xiao-chai-hu-tang for 1.5 months. Laboratory studies disclosed acute hepatitis even though all of the viral hepatitis markers were negative. Liver biopsy also revealed a picture of acute hepatocellular hepatitis. The symptoms improved after discontinuing the drug, and liver biochemical tests normalized 2 months later. The case report reminds us of the probable adverse drug reaction of herbs, even in some that are claimed to have hepatoprotective effects.

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING TAO170W and TAO170W0N in the South Pacific Ocean from 2005-07-04 to 2011-02-04 (NODC Accession 0100078)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0100078 includes chemical, meteorological, physical and time series data collected from MOORING TAO170W and TAO170W0N in the South Pacific Ocean from...

Higher Education and Happiness: The Perspectives of the Bible and Tao Te Ching

Science.gov (United States)

Lee, Jeong-Kyu

2017-01-01

The purpose of this paper is to discuss the concepts and principles of happiness shown in the Bible and Tao Te Ching for implications in higher education. To review the paper systematically, three research questions are addressed. First, what are happiness concepts and principles in the Bible? Second, what are happiness concepts and principles in…

An overview of the China Bioanalytical Forum: interview with Daniel Tang.

Science.gov (United States)

Tang, Daniel

2017-02-01

Daniel Tang talks to Sankeetha Nadarajah, Commissioning Editor (Bioanalysis), regarding the China Bioanalysis Forum (CBF), in which Daniel was one of the co-founders and remains as its co-chair. Daniel is currently the CEO of UP Pharma, a biologics focused bioanalytical CRO in China.

A CPMI da Violência Contra a Mulher e a Implementação da Lei Maria Da Penha

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Carmen Hein de Campos

2015-05-01

Full Text Available Este artigo analisa as conclusões da Comissão Parlamentar Mista de Inquérito da Violência contra a Mulher, criada pelo Congresso Nacional Brasileiro em 2012, no que tange à aplicação da Lei Maria da Penha. Após um ano e meio de trabalho, o relatório da CPMI apontou a fragilidade das políticas públicas de enfrentamento à violência contra mulheres e os obstáculos na implementação da Lei Maria da Penha, dentre os quais, destacam-se: a precariedade da rede de serviços e o reduzido número de juizados especializados em atendimento às mulheres em situação de violência doméstica e familiar; o descumprimento da decisão do Supremo Tribunal Federal que proíbe a aplicação da suspensão condicional do processo; a resistência de operadores/as do direito em entender a proposta da nova lei e romper com a lógica familista e o insuficiente orçamento para o desenvolvimento e a manutenção das políticas públicas de enfrentamento a essas situações de violência. A análise do relatório da CPMI permite concluir que os estados brasileiros investem muito pouco em políticas públicas específicas e que a implementação integral da Lei Maria da Penha depende de uma nova compreensão jurídica, da articulação entre os poderes públicos e de uma política orçamentária de gênero.

Os Meios de Comunicação e a Figura da Mulher: uma reflexão sobre a personagem Clara da telenovela Em Família

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Maria Aparecida Baccega

2016-06-01

Full Text Available O presente artigo tem por objetivo refletir acerca da construção da figura da mulher operada pelos meios de comunicação, através de um dos seus produtos culturais, a telenovela brasileira. Para tanto, propõe uma investigação que aborda a visibilidade da mulher na mídia, trazendo como arcabouço teórico Baccega (1994; 1999, Escosteguy (2011 e Hall (2013, no que tange aos discursos midiáticos; Lippmann (1966, Bourdieu (2002, Scott (1995, Butler (2015 e Louro (2000 para refletir sobre a figura da mulher. Levando em conta o contexto hegemônico, o presente artigo propõe discutir a ideologia bem como a indústria cultural a fim de analisar, como objeto empírico, a personagem Clara, protagonizada pela atriz Giovanna Antonelli, na telenovela brasileira Em Família, da TV Globo.

Rap and Resistance: A Social Movement of the Wu-Tang Clan.

Science.gov (United States)

Chasteen, Amy L.; Shriver, Thomas

1998-01-01

Examines specific collective identity and political expression of the rap group the Wu-Tang Clan. Reveals a multi-layered political strategy that has been conscientiously designed and implemented to instigate a social movement. Prioritizes the voices of marginalized Black peoples and provides raw narratives about oppression. (MMU)

Trauma torácico: importância da antibioticoterapia sobre o tempo de internação

OpenAIRE

Fontelles, Mauro José; Mantovani, Mario

2001-01-01

No que tange a comprovada eficácia da drenagem pleural fechada, grande controvérsia ainda persiste em relação ao uso associado da antibioticoterapia. Os autores estudaram 167 pacientes, com trauma isolado do tórax, com objetivo de avaliar a importância do uso do antibiótico sobre o tempo de internação pós-drenagem pleural fechada. Dois grupos de pacientes foram incluídos num estudo longitudinal e prospectivo de acompanhamento de coortes. O grupo controle incluiu 104 pacientes sem uso da antib...

Enhanced 77 K vortex-pinning in Y Ba2Cu3O7−x films with Ba2Y TaO6 and mixed Ba2Y TaO6 + Ba2Y NbO6 nano-columnar inclusions with irreversibility field to 11 T

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F. Rizzo

2016-06-01

Full Text Available Pulsed laser deposited thin Y Ba2Cu3O7−x (YBCO films with pinning additions of 5 at. % Ba2Y TaO6 (BYTO were compared to films with 2.5 at. % Ba2Y TaO6 + 2.5 at. % Ba2Y NbO6 (BYNTO additions. Excellent magnetic flux-pinning at 77 K was obtained with remarkably high irreversibility fields greater than 10 T (YBCO-BYTO and 11 T (YBCO-BYNTO, representing the highest ever achieved values in YBCO films.

The herbal mixture Xiao-Chai-Hu Tang (XCHT) induces apoptosis of ...

African Journals Online (AJOL)

Background: Xiao-Chai-Hu Tang (XCHT) is an extract of seven herbs with anticancer properties, but its mechanism of action is unknown. In this study, we evaluated XCHT-treated hepatocellular carcinoma (HCC) for anti-proliferative and pro-apoptotic effects. Materials and Methods: Using a hepatic cancer xenograft model, ...

Effects of Chowiseungcheng-tang Extracts on the Preadipocytes Proliferation in 3T3-L1 cell line, Lipolysis of Adipocytes in rat, and Localized Fat Accumulation by extraction methods

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Jae-eun, Lee

2008-03-01

Full Text Available Objectives : The purpose of this study is to investigate the effects of Chowiseungcheng-tang extracts on the preadipocytes proliferation in 3T3-L1 cell line, lipolysis of adipocytes in rat’s epididymal adipocytes and localized fat accumulation of porcine by extraction methods(alcohol and water. Methods : Diminish preadipocytes proliferation and promote lipolysis of adipocytes do primary role to reduce obesity. So, we used 3T3-L1 mouse embryo fibroblasts(preadipocytes and rat epididymal adipocytes from Sprague-Dawley rats to investigate the effects of Chowiseungcheng-tang extracts on the preadipocytes proliferation, lipolysis of adipocytes. They were treated with 0.01, 0.1, 1.0㎎/㎖ Chowiseungcheng-tang alcohol and water extracts. And for the purpose of investigating the effects of Chowiseungcheng-tang alcohol and water extracts on the localized fat accumulation, we injected 0.1, 1.0, 10.0㎎/㎖ Chowiseungcheng-tang extracts to porcine fat tissues and observed histological changes of them. Results : Following results were obtained from the preadipocytes proliferation and lipolysis of adipocytes and histological investigation of fat tissues. 1. Chowiseungcheng-tang extracts suppressed preadipocytes proliferation on the high dosage(especially 1.0㎎/㎖, and especially alcohol extracts had better effects. 2. The alcohol extracts of Chowiseungcheng-tang decreased the activity of glycerol-3-phosphate dehydrogenase(GPDH on the concentrations of 0.1, 1.0㎎/㎖. Alcohol extracts had better effects than water extracts. 3. Chowiseungcheng-tang extracts increased lipolysis of adipocytes on the concentrations of 0.1, 1.0㎎/㎖, and especially on the concentration of 1.0㎎/㎖ alcohol extract of Chowiseungcheng-tang had better effect. 4. The water extract of Chowiseungcheng-tang had significant activity to the destruction of porcine fat cell membranes only on the concentration of 10.0㎎/㎖, but alcohol extracts of Chowiseungcheng-tang had it on all

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING TAO155W and MOORING_TAO155W in the North Pacific Ocean and South Pacific Ocean from 1997-11-14 to 2012-06-11 (NODC Accession 0100084)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0100084 includes chemical, meteorological, physical and time series data collected from MOORING TAO155W and MOORING_TAO155W in the North Pacific Ocean...

Navy John Lewis (TAO 205) Class Oiler Shipbuilding Program: Background and Issues for Congress

Science.gov (United States)

2016-08-18

These wires are placed under tension to support fuel hoses for refueling operations or trolleys that move pallets of provisions, ammunition, or other...SECNAV Mabus Names First TAO(X) Next Generation Oiler After Rep. John Lewis,” USNI News, January 6, 2016. 6 Sam LaGrone, “Navy to Name Ship After Gay

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING_TAO110W and MOORING_TAO110W0N in the North Pacific Ocean from 2009-09-19 to 2013-09-25 (NODC Accession 0112885)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0112885 includes chemical, meteorological, physical and time series data collected from MOORING_TAO110W and MOORING_TAO110W0N in the North Pacific...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from TAO165E8S and TAO165E_8S in the South Pacific Ocean from 2009-06-22 to 2011-11-15 (NODC Accession 0117073)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0117073 includes chemical, meteorological, physical and time series data collected from TAO165E8S and TAO165E_8S in the South Pacific Ocean from...

Contribuições da Teoria Ator-Rede para o Estudo da Sustentabilidade

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Simone Alves Pacheco de Campos

2017-04-01

Full Text Available A sustentabilidade, hoje tema tão em voga, tem suas origens na questão ambiental. Pode-se dizer que a base dos problemas ambientais remonta ao início da ciência, onde o homem, afastando-se da natureza, busca melhor compreendê-la e desenvolver técnicas para dominá-la. Na década de 80, com a promulgação da ideia de desenvolvimento sustentável, a questão social mostra-se intrinsicamente relacionada à ambiental, já não sendo possível tratá-las de modo isolado. Sendo assim, o presente ensaio tem por objetivo apresentar as contribuições da Teoria Ator-Rede (TAR para o estudo da sustentabilidade nas organizações. Esta traz contribuições importantes para os estudos na área, por se tratar de um a teoria que propõe uma modificação em relação ao que se entende por “social”, avançando-se para uma sociologia de associações, onde humanos e não-humanos tem poder de agência. Considerando, de forma específica, os conceitos utilizados pela TAR, nota-se que, especialmente os conceitos de simetria, híbridos, redes, sociologia das associações fornecem ricas discussões no que tange à sustentabilidade.

Physical and meteorological data from the Tropical Atmosphere Ocean (TAO) array in the tropical Pacific Ocean

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National Oceanic and Atmospheric Administration, Department of Commerce — The Tropical Atmosphere Ocean (TAO) Array of 55 moored buoys spans the tropical Pacific from longitudes 165°E to 95°W between latitudes of approximately 8°S and...

OS DIREITOS HUMANOS E FUNDAMENTAIS DA CRIANÇA E OS OBJETIVOS DO MILÊNIO: AVANÇOS E DESAFIOS DO ESTADO E DA SOCIEDADE CIVIL BRASILEIRA

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Renata Guimarães Franco

2015-05-01

Full Text Available A Declaração do Milênio das Nações Unidas de 2000 representou um amplo compromisso envolvendo 190 países em torno de oito metas ou objetivos considerados primordiais para a erradicação da pobreza extrema e suas consequências até este ano de 2015. O presente artigo pretende tecer considerações acerca do alcance das metas pelo Estado Brasileiro no que tange às metas relacionadas à efetivação dos direitos humanos fundamentais da criança utilizando-se para isso de índice e informações colhidos em documentos oficiais do governo brasileiro, mas também em instrumentos de monitoramento e fiscalização de entidades da sociedade civil sobre a temática.

Characterization and identification of in vitro metabolites of ...

African Journals Online (AJOL)

Characterization and identification of in vitro metabolites of (-)-epicatechin using ultra-high performance liquid chromatography-mass spectrometry. Rui Jun Cai, Xiao Ling Yin, Jing Liu, Da Xu Qin, Gui Zhen Zhao ...

Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

Science.gov (United States)

Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

2015-01-01

Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n = 60) and the lorazepam tablet treatment group (n = 59). Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P = 0.029), the PSQI (P = 0.017), and wake after sleep onset (WASO; P = 0.008) scores and improved sleep architecture (P = 0.000–0.003) after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety. PMID:25793006

Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

Directory of Open Access Journals (Sweden)

Lin-lin Hu

2015-01-01

Full Text Available Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT and Zhi Zi Chi Tang (ZZCT; SZR-ZZC for improving sleep quality and anxiety states with four indices of Polysomnography (PSG, the Insomnia Severity Index (ISI, the Pittsburgh Sleep Quality Index (PSQI, and the Self Rating Anxiety Scale (SAS. Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n=60 and the lorazepam tablet treatment group (n=59. Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P=0.029, the PSQI (P=0.017, and wake after sleep onset (WASO; P=0.008 scores and improved sleep architecture (P=0.000–0.003 after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety.

Curanderismo in Taos County, New Mexico--a possible case of anthropological romanticism?

Science.gov (United States)

Scheper-Hughes, N; Stewart, D

1983-12-01

Interviews with 25 Spanish-Americans of Taos County, New Mexico, indicate that time and acculturation have greatly eroded the belief in and practice of curanderismo, the traditional folk medical system of the Southwest. Curanderismo in northern New Mexico today has moved from being a primary and important source of medical care to one used alternatively and very occasionally in cases of pediatric disorders, chronic illnesses and pain, and for those maladies still classified according to the traditional folk beliefs.

Psicogênese da língua escrita, universais lingüísticos e teorias de alfabetização

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Luiz Antonio Gomes Senna

2001-02-01

Full Text Available

O que há entre universais lingüísticos e a psicogênese da língua escrita? Neste artigo, levanto algumas questões polêmicas sobre um possível problema conceituai no uso da lingüística chomskyana numa teoria semiótica de alfabetização. Os universais de Chomsky - baseados no Dispositivo de Aquisição da Linguagem (LAD e numa mente modular - podem comprometer todo o projeto de abordagem psicogenética do desenvolvimento da língua escrita, uma vez que não existe nenhuma motivação filogenética, com base na qual se possa tratar da alfabetização de modo similar Tao empregado para explicar a aquisição da língua materna.

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING TAO140W and MOORING_TAO140W_0N in the North Pacific Ocean and South Pacific Ocean from 2004-05-23 to 2013-07-02 (NODC Accession 0100077)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0100077 includes chemical, meteorological, physical and time series data collected from MOORING TAO140W and MOORING_TAO140W_0N in the North Pacific...

Sipjeondaebo-tang in patients with cancer with anorexia: a protocol for a pilot, randomised, controlled trial.

Science.gov (United States)

Cheon, Chunhoo; Park, Sunju; Park, Yu Lee; Huang, Ching-Wen; Ko, Youme; Jang, Bo-Hyoung; Shin, Yong-Cheol; Ko, Seong-Gyu

2016-05-12

Cancer-related anorexia is the loss of appetite or desire to eat in patients with cancer. Although treatments for cancer-related anorexia do exist, patients have sought complementary and alternative medicine including herbal remedies, due to safety concerns. Sipjeondaebo-tang is one among other popular herbal medicines that are beneficial to management of anorexia in Korea. The purpose of this study is to examine the feasibility for a full randomised clinical trial of Sipjeondaebo-tang for cancer-related anorexia. This study is a randomised, double-blinded and placebo-controlled trial of Sipjeondaebo-tang. For the study, 40 patients with cancer, aged 20-80 years, who reported anorexia, will be recruited. The participants will receive either 3 g of Sipjeondaebo-tang or a placebo, 3 times a day for 4 weeks. The primary end point is a change in the anorexia/cachexia subscale (A/CS) of Functional Assessment of Anorexia/Cachexia Therapy (FAACT). The secondary end points include changes in the visual analogue scale (VAS) of appetite, cortisol and ghrelin. The outcomes will be measured on every visit. Each participant will visit once a week during 4 weeks. The present study has been approved by the Institutional Review Board of the Dunsan Korean Medicine Hospital of Daejeon University (reference DJDSKH-15-03-2 (V.2.0)). The results will be disseminated in a peer-reviewed journal and scientific conference. NCT02468141; Pre-results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Curanderismo in Taos County, New Mexico—A Possible Case of Anthropological Romanticism?

Science.gov (United States)

Scheper-Hughes, Nancy; Stewart, David

1983-01-01

Interviews with 25 Spanish-Americans of Taos County, New Mexico, indicate that time and acculturation have greatly eroded the belief in and practice of curanderismo, the traditional folk medical system of the Southwest. Curanderismo in northern New Mexico today has moved from being a primary and important source of medical care to one used alternatively and very occasionally in cases of pediatric disorders, chronic illnesses and pain, and for those maladies still classified according to the traditional folk beliefs. PMID:6666104

THE IDENTIFICATION OF THE BINDING MEDIA IN THE TANG DYNASTY CHINESE WALL PAINTINGS BY USING Py-GC/MS AND GC/MS TECHNIQUES

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Hong GUO

2011-06-01

Full Text Available The archaeological discoveries of Tang tomb murals in Xi’an, China brought to light unprecedented data for the study of the art of the Tang Dynasty (618-907 AD. The spectacular murals with their particular contents provided first-hand material for the study of Chinese history and the techniques of wall paintings during the Tang Dynasty. In order to gain a better understanding of the materials used and to preserve those paintings, pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS and gas chromatography-mass spectrometry (GC/MS were applied for the characterization of the binding media in the paintings. The combination of these analytical techniques is an ideal methodology to identify binding media in unknown samples.

Physical and meteorological delayed-mode full-resolution data from the Tropical Atmosphere Ocean (TAO) array in the Equatorial Pacific

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Tropical Atmosphere Ocean (TAO) array of moored buoys spans the tropical Pacific. Moorings within the array measure surface meteorological and upper-ocean...

Phase relationships in the BaO-Ga2O3-Ta2O5 system and the structure of Ba6Ga21TaO40.

Science.gov (United States)

Cao, Jiang; Yu, Xiaodi; Kuang, Xiaojun; Su, Qiang

2012-07-16

Phase relationships in the BaO-Ga(2)O(3)-Ta(2)O(5) ternary system at 1200 °C were determined. The A(6)B(10)O(30) tetragonal tungsten bronze (TTB) related solution in the BaO-Ta(2)O(5) subsystem dissolved up to ~11 mol % Ga(2)O(3), forming a ternary trapezoid-shaped TTB-related solid solution region defined by the BaTa(2)O(6), Ba(1.1)Ta(5)O(13.6), Ba(1.58)Ga(0.92)Ta(4.08)O(13.16), and Ba(6)GaTa(9)O(30) compositions in the BaO-Ga(2)O(3)-Ta(2)O(5) system. Two ternary phases Ba(6)Ga(21)TaO(40) and eight-layer twinned hexagonal perovskite solid solution Ba(8)Ga(4-x)Ta(4+0.6x)O(24) were confirmed in the BaO-Ga(2)O(3)-Ta(2)O(5) system. Ba(6)Ga(21)TaO(40) crystallized in a monoclinic cell of a = 15.9130(2) Å, b = 11.7309(1) Å, c = 5.13593(6) Å, β = 107.7893(9)°, and Z = 1 in space group C2/m. The structure of Ba(6)Ga(21)TaO(40) was solved by the charge flipping method, and it represents a three-dimensional (3D) mixed GaO(4) tetrahedral and GaO(6)/TaO(6) octahedral framework, forming mixed 1D 5/6-fold tunnels that accommodate the Ba cations along the c axis. The electrical property of Ba(6)Ga(21)TaO(40) was characterized by using ac impedance spectroscopy.

Pretreatment with Shuanghe-Tang Extract Attenuates Postischemic Brain Injury and Edema in a Mouse Model of Stroke: An Analysis of Medicinal Herbs Listed in Dongui Bogam

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Min Jae Kim

2018-01-01

Full Text Available Aim. Although stroke is among the leading causes of death and long-term disability, there are few effective treatments for limiting the severity of neurological sequelae. We evaluated the effects of 29 medicinal herbs listed in the Pung chapter of the 17th century Korean medical text Dongui Bogam on stroke symptoms in a mouse model of cerebral ischemia. Methods. Focal cerebral ischemia was induced via photothrombosis. Infarct volume, brain edema, and neurological deficits were evaluated. Immunofluorescence staining for tight junction proteins and aquaporin 4 (AQP4 was performed following ischemic injury. Results. Based on our initial findings, we examined the effects of two prescriptions in which the candidate herbs comprised more than 60% of the total formula: Shuanghe-tang and Zengsunsiwu-tang. Pretreatment with Shuanghe-tang significantly reduced infarct volume, decreased blood-brain barrier (BBB breakdown, attenuated edema, and improved neurological and motor functions in a dose-dependent manner (30, 100, and 300 mg/kg, while no such effects were observed in mice pretreated with Zengsunsiwu-tang. Immunohistochemical analysis revealed significant increases in ipsilateral occludin and zonula occludens 1 (ZO-1 expression in Shuanghe-tang-pretreated mice, as well as increased AQP4 immunofluorescence. Conclusions. These results indicate that Shuanghe-tang may protect against brain injury and promote recovery of neurological function following ischemia.

Desde os conceitos estruturantes da arquitectura clássica japonesa : análise e interpretação de dois casos de estudo de arquitectura contemporânea

OpenAIRE

Cacela, Susana Maria de Castro Figueiredo Valente, 1989-

2016-01-01

Dissertação de mestrado integrado em Arquitectura, Universidade Lusíada de Lisboa, 2016 Exame público realizado em 13 de Maio de 2016 É objecto de estudo da presente dissertação a análise e estudo dos fundamentos e conceitos estruturantes da Arquitectura Clássica Japonesa, fase da arquitectura ligada à imagem, a valores intemporais, tangíveis, e rituais, pilares da Arquitecura Japonesa, e que este trabalho recupera oportunamente para a agenda contemporânea. Sabendo que Álvaro Siza Vi...

Análise das ações dos revendedores varejistas nos pontos de venda em relação à estratégia de reposicionamento da marca Havaianas

OpenAIRE

Breunig, Jairo

2006-01-01

Estratégias competitivas podem envolver diversos aspectos da empresa, desde fatores tangíveis como custos de produção a intangíveis como o valor da marca. Neste caso, estratégias de valorização da marca incluem ações do fabricante que se refletem sobre os revendedores de suas marcas, exigindo que ambas estejam em sintonia. O objetivo deste trabalho é comparar as ações realizadas pelos revendedores varejistas com a estratégia de reposicionamento da marca Havaianas, produzida pela empresa Alpar...

Geologic map of the Sunshine 7.5' quadrangle, Taos County, New Mexico

Science.gov (United States)

Thompson, Ren A.; Turner, Kenzie J.; Shroba, Ralph R.; Cosca, Michael A.; Ruleman, Chester A.; Lee, John P.; Brandt, Theodore R.

2014-01-01

The Sunshine 7.5' quadrangle is located in the south-central part of the San Luis Basin of northern New Mexico, in the Rio Grande del Norte National Monument, and contains deposits that record volcanic, tectonic, and associated alluvial and colluvial processes over the past four million years. Sunshine Valley, named for the small locale of Sunshine, is incised by a series of northeast-trending drainages cut into Tertiary and Quaternary alluvial deposits forming an extensive alluvial apron between the east flank of the Sangre de Cristo Mountains and the Rio Grande. These deposits predominantly overlie gently eastward-dipping lava flows of Pliocene Servilleta Basalt erupted from centers west of the map area. Servilleta Basalt lava flows terminate to the south against the elevated topography of three volcanic centers of the Taos Plateau volcanic field. From west to east these are Cerro de la Olla, Cerro Chiflo, and Guadalupe Mountain that are exposed in the southern part of the map area. Remnants of Miocene volcanic rocks are exposed near the southwestern edge of the map area and record evidence of an eroded volcanic terrain underlying deposits of the Taos Plateau volcanic field. These deposits are likely fault bounded to the east, roughly coincident with north to northwest trending, down-to-east faults in the southwestern quarter of the map area. The down-to-east normal faults reflect the basinward migration of the western margin of the Sunshine Valley sub-basin of the southern San Luis Basin.

Na5NbO5 and Na5TaO5 phases

International Nuclear Information System (INIS)

Darriet, J.; Maazaz, A.; Bouloux, J.C.; Delmas, C.

1982-01-01

New ternary oxides of formulas Na 5 NbO 5 and Na 5 TaO 5 have been prepared. They crystallize in the monoclinic system (space group C2/c). The crystal structure of Na 5 NbO 5 has been determined. It derives from a NaCl-type structure by ordering of the cations and of the oxygen vacancies in the anionic sublattice, the corresponding formula being Nasub(5/6)Nbsub(1/6)Osub(5/6)vacant sub(1/6). Sodium and niobium have a distorted square-pyramidal surrounding. (author)

Yukmijihwang-tang for the treatment of xerostomia in the elderly: study protocol for a randomized, double-blind, placebo-controlled, two-center trial.

Science.gov (United States)

Han, Gajin; Park, Jae-Woo; Ko, Seok-Jae; Son, Jihee; Seon, Jongki; Kim, Juyeon; Kim, Seulki; Yeo, Inkwon; Ryu, Bongha; Kim, Jinsung

2013-09-03

Xerostomia, a subjective sense of dry mouth, is not generally regarded a disease despite its high prevalence among the elderly, and therefore continues to impair affected patients' quality of life. In traditional Korean medicine, 'Yin-Deficiency' has been implicated in the pathogenesis of xerostomia among the elderly. Yukmijihwang-tang is a famous herbal prescription used to relieve 'Yin-Deficiency', and reportedly has antioxidant effects; therefore, it is postulated that Yukmijihwang-tang can be used to treat xerostomia in the elderly. However, to our knowledge, no clinical trial has been conducted on the effects of Yukmijihwang-tang on xerostomia. Thus, we designed a randomized clinical trial to investigate the effects and safety of Yukmijihwang-tang on xerostomia in the elderly. In addition, we will clarify the aforementioned assumption that 'Yin-Deficiency' is the major cause of xerostomia in the elderly by identifying a correlation between xerostomia and 'Yin-Deficiency'. This randomized, double-blind, placebo-controlled trial will be carried out at two centers: Kyung Hee University Korean Medicine Hospital and Kyung Hee University Hospital at Gangdong. We will recruit 96 subjects aged 60-80 years who have experienced xerostomia for 3 months prior to participation. Subjects who present with score >40 on the visual analogue scale for xerostomia and unstimulated salivary flow rate under 0.3mL/min will be included and the randomization will be carried out by an independent statistician by using a random number creation program. The subjects and all researchers except the statistician will be blinded to the group assignment. Yukmijihwang-tang or placebo will be administered to each group for 8 weeks. The primary outcome is change in the scores for the visual analogue scale for xerostomia and the dry mouth symptom questionnaire from 0 to 8 weeks. It will be assessed whether Yukmijihwang-tang can be used as a new herbal treatment for xerostomia in the elderly by

As criações do gênio: Ambivalências da "metafísica da arte" nietzschiana

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Clademir Luís Araldi

2009-06-01

Full Text Available As criações do gênio apolíneo-dionisíaco estão no centro das preocupações da metafísica de artista, e suscitam a questão acerca do vínculo de Nietzsche com a estética do Romantismo Alemão e de Schopenhauer. Investigamos neste artigo as ambivalências do pensamento nietzschiano no que tange ao conflito entre a arte apolínea da ilusão e a sabedoria dionisíaca, entre o Uno-Primordial e a aparência.The creations of the apollinian-dionysian genius are in the center of the concerns of the artist's metaphysics and raise the question about the relationship of Nietzsche to the aesthetics of German Romanticism and Schopenhauer's. In this article we investigate the ambivalences of the Nietzschean thinking regarding the conflict between the apollinian art of illusion and the Dionysian wisdom, between the Primordial-One and the appearance.

VIDEOCONFERÊNCIA NO ENSINO À DISTÂNCIA: RENOVAÇÃO DA PRÁTICA EDUCATIVA

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Patrícia Mousquer

2016-11-01

Full Text Available Apresenta relato de experiência quanto à utilização de videoconferência, por meio do software Adobe Connect, versão 9, empregado como ferramenta de apoio na disciplina de Formação e Desenvolvimento de Coleção do Curso de Biblioteconomia da Universidade de Caxias do Sul, ofertado na modalidade a distância. O resultado do uso desse software demonstrou sua pertinência no suporte às aulas síncronas contribuindo para o desenvolvimento da competência em informação específica no que tange ao ensino a distância.

[Evaluation study on integration effect of taohong siwu tang in treating primary dysmenorrhea].

Science.gov (United States)

Liu, Li; Duan, Jin-Ao; Hua, Yong-Qing; Liu, Pei; Shang, Er-Xin; Tang, Yu-Ping; Su, Shu-Lan

2012-11-01

To evaluate the effect of Taohong Siwu Tang and its fractions on hotplate-induced pain in mice, acetic acid-induced writhing response, dysmenorrheal model and isolated uterine contraction in vitro in mice, and discuss material basis of effect sites. The samples of fractions were prepared by macroporous adsorptive resins (TH-1-TH-15). In the whole animal experiment, the hotplate-induced pain mice model was established to observe the effect of the samples on pain threshold in mice; the acetic acid-induced writhing response mice model was built to observe the effect of the samples on the writhing response in mice; the mice dysmenorrheal model was established to observe the effect of the samples on the writhing response, and calcium ion (Ca2+) and nitric oxide (NO) levels in uterine tissue of mice. In the isolated uterus contraction experiment, the oxytocin-induced isolated uterus contraction mice model was established to observe the effect of the samples on the isolated uterus contraction index. HPLC-DAD method was adopted for the content determination of effect sites. According to the evaluation of the integration geological effect, beside TH-2 and TH-4, other three active fractions (TH-9, TH-10 and TH-11) extracted from Taohong Siwu Tang are the main effect sites. Their chemical components were analyzed and identified as monoterpene glycosides, phthalides, organic acids, etc. The effect sites of Taohong Siwu Tang on dysmenorrhea are TH-9, TH-10 and TH-11, which are 30% - 50% active fractions obtained from water-soluble small-molecular fractions by gradient elution using ethanol through macroporous absorption resin. Compared with TH-10 and TH-11, TH-9 shows stronger effect, which may be related to the type and content of chemical components it contains.

The Conflict Argument of "Desire"between Tang Romance Studies and Taoism%唐代传奇文学与道教关于“人欲”的冲突

Institute of Scientific and Technical Information of China (English)

崔明明

2014-01-01

Tang Romance Novels are symbolized the maturity of Chinese classical novels .As the wide-spread of Taoist culture ,Tang Romance absorbed Taoist culture .And on the one hand they also make full use of their advantages to present Taoism ,by showing people their unique life that lived in Tang Dynasty . Taoism ,as an indigenous religion ,its theory combined with Tang romance stories ,too .With the help of the tang literary genre ,it is easy to understand the Taoist esoteric knowledge and conception .Even Tang romance stories and Taoism have multiple relationships ,they still have conflict about "Desire":Taoism has thought of abstinence ,while in the literature of Tang romance stories it has more humanity and inspi-rations .%唐传奇是中国文言小说成熟的标志。作为道教文化的宣传者，唐传奇吸收道教的文化底蕴，一方面充分运用自身的优势阐释道教思想，另一方面展现了自身的独特生机。道教作为本土宗教，其理论与唐传奇紧密结合，道家深奥的学问借助唐传奇的文学体裁得以通俗易懂地展现。唐传奇与道教有着多重关系，除了互利的方面外，道教具有禁欲思想，而作为文学，唐传奇具有人文情怀和启迪作用，二者在宣传“人欲”方面存在冲突。

Effects of electroacupuncture and electroacupuncture plus Tao Hong Si Wu Wan in treating primary dysmenorrhea.

Science.gov (United States)

Miao, Edwin Yong; Miao, Miranda Yi-mo; Kildea, Daniel George; Lao, Yi-Wen

2014-02-01

This study investigated the efficacies of electroacupuncture and electroacupuncture combined with Tao Hong Si Wu Wan in treating primary dysmenorrhea and compared the results with those obtained using conventional medical treatment. One treatment group, group 1, was administered Tao Hong Si Wu Wan (2625 mg) while the other, group 2, was administered a placebo (2625 mg) twice daily for 3 months. Electroacupuncture was used in both treatment groups: two sessions per menstrual cycle for three menstrual cycles. The reference group, group 3, was administered ibuprofen, 600 mg, twice daily, for five menstrual cycles. Uses of the herb, placebo and ibuprofen were blinded. A ridit analysis was used for testing and interpreting the effects of treatment. Pain intensity was determined using a qualitative grading method in a blinded manner. The ridit scores in groups 1 and 2 were significantly higher than those in reference group immediately after treatment and three months later. Twelve months after the treatment, group 1 had a higher ridit score than group 2. In comparison to the reference group, groups 1 and 2 achieved better menstrual pain relief both immediately and 3 months after treatment. In addition, group 1 had better long-term pain relief than group 2. Copyright © 2014. Published by Elsevier B.V.

Tipo de perda e qualidade da recuperação em transgressões no relacionamento B2C

OpenAIRE

Schwarzbach, Loise Cristina

2015-01-01

Orientadora : Profª. Drª. Danielle Mantovani Lucena da Silva Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Sociais Aplicadas, Programa de Pós-Graduação em Administração. Defesa: Curitiba, 30/03/2015 Inclui referências : fls. 116-124 Resumo: O objetivo desta pesquisa foi verificar a influência do tipo de perda (tangível vs psicológica) e do desempenho da recuperação (alta vs media vs baixa) de transgressões no relacionamento B2C - Business to Consumer sobr...

The quark induced Mueller-Tang jet impact factor at next-to-leading order

CERN Document Server

Hentschinski, M.; Murdaca, B.; Vera, A. Sabio

2014-01-01

We present the NLO corrections for the quark induced forward production of a jet with an associated rapidity gap. We make use of Lipatov's QCD high energy effective action to calculate the real emission contributions to the so-called Mueller-Tang impact factor. We combine them with the previously calculated virtual corrections and verify ultraviolet and collinear finiteness of the final result.

Prey selection of corallivorous muricids at Koh Tao (Gulf of Thailand) four years after a major coral bleaching event

NARCIS (Netherlands)

Moerland, M.S.; Scott, C.M.; Hoeksema, B.W.

2016-01-01

Corallivorous Drupella (Muricidae) snails at Koh Tao are reported to have extended their range of prey species following a major coral bleaching event in 2010. Populations of their preferred Acropora prey had locally diminished in both size and abundance, and the snails had introduced free-living

[Textual research on Costus root (Aucklandia lappa Decne) in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica)].

Science.gov (United States)

Li, Guangyan; Wang, Dequn; Fang, Shiying; Xu, Maohong

2014-05-01

Aucklandia lappa Decne was first recorded in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica). Through the textual research of herbal literature, it was found that the costus root in the Sheng nong ben cao jing perhaps was not the plant of Aucklandia lappa Decne of Compositae, but the eaglewood or Lignum Aquilasria Resinatum based on the comprehensive judgment of shape, taste, nature, and function etc. In the Sheng nong ben cao jing, it only includes costus root without the title of eaglewood, and Tao Hongjing recorded both herbs together in his Ming yi bie lu (Supplementary Records of Celebrated Physicians), which became a foreshadow of misunderstanding of the later generations. Beginning from the Tang ben cao (Materia Medica of the Tang Dynasty), the costus root was considered as the plant of Auckiandia lappa Decne from the Compostae with its profound influence until now.

Aquisição da linguagem e habilidades cognitivas superiores: o papel da língua no desenvolvimento da cognição numérica

Directory of Open Access Journals (Sweden)

Mercedes Marcilese

2012-12-01

Full Text Available Este artigo tem como objetivo principal analisar o possível papel da posse de uma língua natural na configuração de uma cognição numérica sofisticada, distintiva da espécie humana. O trabalho fornece uma introdução a uma das principais perspectivas teóricas da atualidade no que tange à conformação da cognição humana, a chamada hipótese dos sistemas nucleares (SPELKE et al., 1992; SPELKE; Kinzler, 2007, assim como também um panorama completo e atualizado de estudos relativos à cognição numérica, incluindo resultados de uma pesquisa recente conduzida no Brasil. Assume-se aqui que a língua seria responsável pela combinação das representações fornecidas por dois sistemas básicos para o processamento da numerosidade. Um desses sistemas representaria quantidades aproximadas, enquanto o outro seria responsável pela representação de numerosidades pequenas, processadas a partir da identificação em paralelo dos indivíduos. É defendida a ideia de que - no que se refere ao desenvolvimento do conceito de número, mas também de uma forma mais geral - a língua teria uma especial relevância na integração de informações, colaborando na expansão do alcance dos conceitos da criança ao possibilitar a combinação de itens do léxico associados a diferentes tipos de representações não verbais.

Pegada ecológica da atividade agropecuária na Amazônia: o caso do estado do Acre

OpenAIRE

Padrão, Glaucia de Almeida

2010-01-01

Desde fins da década de 1960, o mundo vem passando por transformações significativas no que tange o pensamento econômico sobre a questão ambiental. No Brasil, apesar de mais de meio século de pesquisas que visam a integração entre economia e meio ambiente, tem havido aumento significativo das taxas de desmatamento nas regiões norte e nordeste do pais, desencadeado pelo processo de expansão da atividade agropecuária para estas regiões. Essa expansão resultou no desmatamento de uma área que vai...

Evolution of the Orszag-Tang vortex system in a compressible medium. II - Supersonic flow

Science.gov (United States)

Picone, J. Michael; Dahlburg, Russell B.

1991-01-01

A study is presented on the effect of embedded supersonic flows and the resulting emerging shock waves on phenomena associated with MHD turbulence, including reconnection, the formation of current sheets and vortex structures, and the evolution of spatial and temporal correlations among physical variables. A two-dimensional model problem, the Orszag-Tang (1979) vortex system, is chosen, which involves decay from nonrandom initial conditions. The system is doubly periodic, and the initial conditions consist of single-mode solenoidal velocity and magnetic fields, each containing X points and O points. The initial mass density is flat, and the initial pressure fluctuations are incompressible, balancing the local forces for a magnetofluid of unit mass density. Results on the evolution of the local structure of the flow field, the global properties of the system, and spectral correlations are presented. The important dynamical properties and observational consequences of embedded supersonic regions and emerging shocks in the Orszag-Tang model of an MHD system undergoing reconnection are discussed. Conclusions are drawn regarding the effects of local supersonic regions on MHD turbulence.

LITERATURA INFANTIL E CURRÍCULO – OS ENTRE-LUGARES DA FORMAÇÃO DOS PEDAGOGOS

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Rute Pereira Alves de Araújo

2014-09-01

Full Text Available O presente trabalho é parte de um estudo de caso realizado durante o curso de doutorado em Educação e tem por objetivo refletir a formação dos pedagogos de três instituições de Ensino Superior do estado da Paraíba, a partir da análise documental da resolução CNE/CP Nº 1, de 15 de Maio de 2006; Proposta Pedagógica dos Cursos de Pedagogia e planos de cursos da disciplina Literatura Infantil dessas Instituições, analisando os entre-lugares/interstícios (BHABHA, 1998 da política curricular dos Cursos de Pedagogia no que tange a formação de professores e a sua preparação para o ensino da leitura literária. Os dados levantados evidenciam que as cargas horárias das disciplinas de Literatura Infantil se tornam insuficientes face à formação necessária ao educador de crianças e jovens.

Serum Metabolomic Characterization of Liver Fibrosis in Rats and Anti-Fibrotic Effects of Yin-Chen-Hao-Tang

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Hongyang Zhang

2016-01-01

Full Text Available Yin-Chen-Hao-Tang (YCHT is a famous Chinese medicine formula which has long been used in clinical practice for treating various liver diseases, such as liver fibrosis. However, to date, the mechanism for its anti-fibrotic effects remains unclear. In this paper, an ultra-performance liquid chromatography-time-of-flight mass spectrometry (UPLC-TOF-MS-based metabolomic study was performed to characterize dimethylnitrosamine (DMN-induced liver fibrosis in rats and evaluate the therapeutic effects of YCHT. Partial least squares-discriminant analysis (PLS-DA showed that the model group was well separated from the control group, whereas the YCHT-treated group exhibited a tendency to restore to the controls. Seven significantly changed fibrosis-related metabolites, including unsaturated fatty acids and lysophosphatidylcholines (Lyso-PCs, were identified. Moreover, statistical analysis demonstrated that YCHT treatment could reverse the levels of most metabolites close to the normal levels. These results, along with histological and biochemical examinations, indicate that YCHT has anti-fibrotic effects, which may be due to the suppression of oxidative stress and resulting lipid peroxidation involved in hepatic fibrogenesis. This study offers new opportunities to improve our understanding of liver fibrosis and the anti-fibrotic mechanisms of YCHT.

Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan.

Science.gov (United States)

Chao, Te-Hsin; Fu, Pin-Kuei; Chang, Chiung-Hung; Chang, Shih-Ni; Chiahung Mao, Frank; Lin, Ching-Heng

2014-08-08

Traditional Chinese medicine (TCM) is commonly provided to cancer patients, however, the patterns of prescriptions for this type of medicine in Taiwan are unclear. This study aimed to evaluate the use of traditional Chinese medicine products in colon cancer patients post-surgery in Taiwan and to research patterns of TCM. This was a cross-sectional study of newly diagnosed colon cancer patients who received surgery between 2004 and 2008 identified from the National Health Insurance Research Database of Taiwan. The prescription patterns and reasons for the use of TCM for colon cancer were analyzed. The results showed that "symptoms, signs and ill-defined conditions" (23.3%) and diseases of the digestive system (16.9%) were the most common reasons for using Chinese herbal medicine. Xiang-sha-liu-jun-zi-tang (7.1%), Bu-zhong-yi-qi-tang (4.3%), Jia-wei-xiao-yao-san (4.1%), Shen-Ling-Bai-Zhu-San (3.7%), Ban-Xia-Xie-Xin-Tang (3.4%), Gui-pi-tang (2.4%), Ping-Wei-San (2.4%), Gan-Lu-Yin (2.0%), Bao-He-Wan (1.9%), and Zhen-Ren-Huo-Ming-Yin (1.8%) were the most commonly prescribed single Chinese herbal formulae (CHF) for colon cancer patients post-surgery. Hedyotis diffusa Willd (Bai Hua She She Cao) (5.1%) and Scutellaria barbata (Ban Zhi Lian )(4.8%) were the most commonly prescribed single Chinese herbs. This study identified patterns of TCM use in colon cancer patients post-surgery in Taiwan. The herbal ingredients were most commonly used for stimulate ghrelin secretion to increase food intake and had potential anti-tumor effect. However, further research is required to evaluate any beneficial effects which could identify leads for the development of new treatment strategies using TCM. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Arsenic Removal from Drinking Water by Adsorptive Media - U.S. EPA Demonstration Project at Taos, NM, Final Performance Evaluation Report

Science.gov (United States)

This report documents the activities performed and the results obtained for the EPA arsenic removal technology demonstration project at the Town of Taos in New Mexico. The main objective of the project was to evaluate the effectiveness of Severn Trent Services’ (STS) SORB 33™ ad...

O Réu sem rosto: a importância da audiência de custódia no processo penal sob a ótica da economia comportamental

OpenAIRE

Silva, Leandro de Castro

2014-01-01

Neste artigo são discutidas formas de promover a melhoria da política pública prisional brasileira especialmente no que tange o preso provisório, com enfoque nas contribuições que a economia comportamental pode fornecer ao direito. A questão central do debate é como o modelo processual atualmente adotado não cria um ambiente favorável à liberdade, na medida em que não promove o diálogo entre o acusado e seu julgador. Os estudos econômicos, assim, podem nos fornecer importantes lições de como ...

The Gluon-Induced Mueller-Tang Jet Impact Factor at Next-to-Leading Order

CERN Document Server

Hentschinski, Martin; Murdaca, Beatrice; Vera, Agustín Sabio

2014-01-01

We complete the computation of the Mueller-Tang jet impact factor at next-to-leading order (NLO) initiated in arXiv:1406.5625 and presented in arXiv:1404.2937 by computing the real corrections associated to gluons in the initial state making use of Lipatov's effective action. NLO corrections for this effective vertex are an important ingredient for a reliable description of large rapidity gap phenomenology within the BFKL approach.

Hydrological Responses of Climate and Land Use/Cover Changes in Tao'er River Basin Based on the SWAT Model

Science.gov (United States)

Liu, J.; Kou, L.

2015-12-01

Abstract: The changes of both climate and land use/cover have some impact on the water resources. For Tao'er River Basin, these changes have a direct impact on the land use pattern adjustment, wetland protection, connection project between rivers and reservoirs, local social and economic development, etc. Therefore, studying the impact of climate and land use/cover changes is of great practical significance. The Soil and Water Assessment Tool (SWAT) is used as the research method. With historical actual measured runoff data and the yearly land use classification caught by satellite remote sensing maps, analyze the impact of climate change on the runoff of Tao'er River. And according to the land use/cover classification of 1990, 2000 and 2010, analyze the land use/cover change in the recent 30 years, the impact of the land use/cover change on the river runoff and the contribution coefficient of farmland, woodland, grassland and other major land-use types to the runoff. These studies can provide some references to the rational allocation of water resource and adjustment of land use structure in this area.

Sistema de Gestão pela Qualidade: uma pesquisa na seara da Gestão Pública

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Marcos dos Santos

2016-07-01

Full Text Available No atual cenário onde existe demanda por parte da sociedade por serviços públicos de qualidade é possível perceber uma maior preocupação com sistemas de gestão da qualidade. As organizações contratantes de bens e serviços passam a estender seus requisitos de qualidade para suas contratadas, exigindo assim que essas passem a adotar sistemas de gestão da qualidade e de gestão ambiental e apresentem, no momento de sua contratação, certificações nesses sistemas de gestão. Nesse contexto, o presente artigo tem por objetivo investigar os fatores restritivos e os facilitadores afetos à certificação em gestão da qualidade e da gestão ambiental em duas organizações da Administração Pública. No que tange à seara metodológica, o presente artigo aplica a técnica do incidente crítico, proposta por Flanagan (1973. Os instrumentos de coleta de dados utilizados foram as entrevistas não estruturadas com profissionais pertencentes ao quadro funcional das organizações pesquisadas. Adicionalmente, foi empreendido o levantamento de dados por meio de questionários - contendo perguntas fechadas e abertas - disponibilizados por e-mail. No que tange aos dados coletados a partir das entrevistas face a face e dos questionários, foi empreendida a análise multiparadigmal de Meyerson e Martin (1987, a qual consiste em promover o relacionamento das percepções de determinado grupo com as perspectivas da Integração, Diferenciação e Fragmentação. Verificou-se que, nos dias atuais, as certificações assumem um papel relevante na seara empresarial, revelando-se como um diferencial competitivo no contexto globalizado, tanto para contratantes como contratadas. Contudo, questão crucial é observada quando as certificações deixam de ser uma atividade “meio” e passam a ser uma atividade “fim”, implicando em significativo dispêndio de recursos materiais e humanos.

A shifting rift—Geophysical insights into the evolution of Rio Grande rift margins and the Embudo transfer zone near Taos, New Mexico

Science.gov (United States)

Grauch, V.J.S.; Bauer, Paul W.; Drenth, Benjamin J.; Kelson, Keith I.

2017-01-01

We present a detailed example of how a subbasin develops adjacent to a transfer zone in the Rio Grande rift. The Embudo transfer zone in the Rio Grande rift is considered one of the classic examples and has been used as the inspiration for several theoretical models. Despite this attention, the history of its development into a major rift structure is poorly known along its northern extent near Taos, New Mexico. Geologic evidence for all but its young rift history is concealed under Quaternary cover. We focus on understanding the pre-Quaternary evidence that is in the subsurface by integrating diverse pieces of geologic and geophysical information. As a result, we present a substantively new understanding of the tectonic configuration and evolution of the northern extent of the Embudo fault and its adjacent subbasin.We integrate geophysical, borehole, and geologic information to interpret the subsurface configuration of the rift margins formed by the Embudo and Sangre de Cristo faults and the geometry of the subbasin within the Taos embayment. Key features interpreted include (1) an imperfect D-shaped subbasin that slopes to the east and southeast, with the deepest point ∼2 km below the valley floor located northwest of Taos at ∼36° 26′N latitude and 105° 37′W longitude; (2) a concealed Embudo fault system that extends as much as 7 km wider than is mapped at the surface, wherein fault strands disrupt or truncate flows of Pliocene Servilleta Basalt and step down into the subbasin with a minimum of 1.8 km of vertical displacement; and (3) a similar, wider than expected (5–7 km) zone of stepped, west-down normal faults associated with the Sangre de Cristo range front fault.From the geophysical interpretations and subsurface models, we infer relations between faulting and flows of Pliocene Servilleta Basalt and older, buried basaltic rocks that, combined with geologic mapping, suggest a revised rift history involving shifts in the locus of fault activity as

Tang dynasty (618-907) bowl measured with PIXE

Science.gov (United States)

Laitinen, M.; Käyhkö, M.; Hahn, G.; von Uexküll-Güldenband, N.; Sajavaara, T.

2017-09-01

Brownish bowl originating from an underwater shipwreck located near Belitung island in the Java Sea, some 600 km south-east from Singapore, has been measured with particle induced X-ray emission. This study was a pilot project for the - now a spin-off company - Recenart research team where one target was to evaluate the authenticity of the different type of art objects. PIXE measurements were done from three different material positions from a single bowl received from a customer. These locations were categorized as a bluish/greenish pigment (under glaze), thick glaze and the body clay. When the obtained data was compared to the other references from different dynasties and kiln sites, the closest match was indeed the Tang dynasty, Tongguan/Ghangsha kiln-site potsherds - from where the bowl in question was also suspected to originate.

Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong.

Science.gov (United States)

Tang, Yuping; Zhu, Min; Yu, Sheng; Hua, Yongqing; Duan, Jin-Ao; Su, Shulan; Zhang, Xu; Lu, Yin; Ding, Anwei

2010-01-15

Phthalides are important bio-active constituents in Si-Wu-Tang and Fo-Shou-San, two commonly used Traditional Chinese Medicine (TCM) combined prescriptions mainly derived from Radix Angelica and Rhizoma Chuanxiong. In this paper, the contents of eight phthalides, including Z-ligustilide, E-ligustilide, Z-butylenephthalide, E-butylene-phthalide, 3-butylphthalide, neocnidilide and senkyunolide A were determined or estimated by gas chromatography-mass spectrometry (GC-MS). The results showed GC-MS was a simple, rapid, and high sensitive method for analyzing phthalides in Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong, and the extractable contents of each phthalides including Z-ligustilide, E-ligustilide, Z-butylenephthalide, etc. varied after Radix Angelica, Rhizoma Chuanxiong were combined into a formulation, such as Si-Wu-Tang and Fo-Shou-San. Furthermore, inhibition activity of essential oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong on uterine contraction was tested in an in vitro assay, and the results showed that the activity of the essential oil is higher as the content of the phthalides increase, which demonstrated that phthalides are possibly main active components inhibiting mice uterine contraction in vitro. All of the results suggested that comparative analysis of chemical components and pharmacological activities of each herb and formula is possibly helpful to elucidate the active components in traditional Chinese medicine, and to reveal the compatibility mechanism of TCM formulae.

Elemental analyses on porcelains of Tang and Song Dynasties excavated from Yongjinwan zone at Jinsha site

Science.gov (United States)

Xia, C. D.; Ge, L. J.; Liu, M. T.; Zhu, J. J.; An, Z.; Bai, B.

2018-02-01

The work presented here carried out elemental analyses on 60 porcelain shards of Tang and Song Dynasties, unearthed from Yongjinwan zone at Jinsha site, Sichuan, China, using a combination of PIXE and RBS methods. Six shards from Liulichang kiln site and 6 from Shifangtang kiln site were also analyzed as reference materials. The factor analyses for the elemental compositions in the bodies and glazes of the total 72 porcelain shards have been performed to explore their similarities and differences. Combining the results of factor analyses on elements in bodies and glazes and the classification by traditional archaeological criteria, the provenances for most of shards unearthed from Yongjinwan zone in Jinsha site could be determined. Majority of shards with a Qiong-kiln style were found as products of Liulichang kiln, this is consistent with Yongjinwan's geographical location and social environment, i.e., Yongjinwan was a suburban settlement nearest to Liulichang kiln in ancient times. Although both products of Liulichang kiln and Shifangtang kiln belonged to Qiong-kiln system and they shared a similar appearance such as red body and celadon glaze, there were distinct differences in chemical composition which could be unraveled by PIXE-RBS measurements and factor analysis. There were no apparent differences of chemical compositions for the same kinds of body and glaze between Tang and Song Dynasties, which may suggest that raw materials and production techniques for the same kinds of body and glaze continued between Tang and Song Dynasties. The chemical characteristics for each kind of body and glaze and the correlations between element composition and porcelain appearance were also obtained in this work.

The effect of different oxygen exchange layers on TaO x based RRAM devices

Science.gov (United States)

Alamgir, Zahiruddin; Holt, Joshua; Beckmann, Karsten; Cady, Nathaniel C.

2018-01-01

In this work, we investigated the effect of the oxygen exchange layer (OEL) on the resistive switching properties of TaO x based memory cells. It was found that the forming voltage, SET-RESET voltage, R off, R on and retention properties are strongly correlated with the oxygen scavenging ability of the OEL, and the resulting oxygen vacancy formation ability of this layer. Higher forming voltage was observed for OELs having lower electronegativity/lower Gibbs free energy for oxide formation, and devices fabricated with these OELs exhibited an increased memory window, when using similar SET-RESET voltage range.

Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

Science.gov (United States)

Chan, Yuan-Yu; Chen, Yi-Hung; Yang, Szu-Nian; Lo, Wan-Yu; Lin, Jaung-Geng

2015-01-01

Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI) scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed traditional Chinese medications for treatment of insomnia, improves subjective sleep among methadone-maintained persons with disturbed sleep quality. Ninety patients were randomly assigned to intervention group (n = 45) and placebo group (n = 45), and all participants were analyzed. Compared with placebo treatment, Suan Zao Ren Tang treatment for four weeks produced a statistically significant improvement in the mean total PSQI scores (P = 0.007) and average sleep efficiency (P = 0.017). All adverse events (e.g., lethargy, diarrhea, and dizziness) were mild in severity. Suan Zao Ren Tang is effective for improving sleep quality and sleep efficiency among methadone-maintained patients with sleep complaints. PMID:26346534

Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

Directory of Open Access Journals (Sweden)

Yuan-Yu Chan

2015-01-01

Full Text Available Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed traditional Chinese medications for treatment of insomnia, improves subjective sleep among methadone-maintained persons with disturbed sleep quality. Ninety patients were randomly assigned to intervention group (n=45 and placebo group (n=45, and all participants were analyzed. Compared with placebo treatment, Suan Zao Ren Tang treatment for four weeks produced a statistically significant improvement in the mean total PSQI scores (P=0.007 and average sleep efficiency (P=0.017. All adverse events (e.g., lethargy, diarrhea, and dizziness were mild in severity. Suan Zao Ren Tang is effective for improving sleep quality and sleep efficiency among methadone-maintained patients with sleep complaints.

A musculoskeletal model of low grade connective tissue inflammation in patients with thyroid associated ophthalmopathy (TAO: the WOMED concept of lateral tension and its general implications in disease

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Moncayo Helga

2007-02-01

Full Text Available Abstract Background Low level connective tissue inflammation has been proposed to play a role in thyroid associated ophthalmopathy (TAO. The aim of this study was to investigate this postulate by a musculoskeletal approach together with biochemical parameters. Methods 13 patients with TAO and 16 controls were examined. Erythrocyte levels of Zn, Cu, Ca2+, Mg, and Fe were determined. The musculoskeletal evaluation included observational data on body posture with emphasis on the orbit-head region. The angular foot position in the frontal plane was quantified following gait observation. The axial orientation of the legs and feet was evaluated in an unloaded supine position. Functional propioceptive tests based on stretch stimuli were done by using foot inversion and foot rotation. Results Alterations in the control group included neck tilt in 3 cases, asymmetrical foot angle during gait in 2, and a reaction to foot inversion in 5 cases. TAO patients presented facial asymmetry with displaced eye fissure inclination (mean 9.1° as well as tilted head-on-neck position (mean 5.7°. A further asymmetry feature was external rotation of the legs and feet (mean 27°. Both foot inversion as well as foot rotation induced a condition of neuromuscular deficit. This condition could be regulated by gentle acupressure either on the lateral abdomen or the lateral ankle at the acupuncture points gall bladder 26 or bladder 62, respectively. In 5 patients, foot rotation produced a phenomenon of moving toes in the contra lateral foot. In addition foot rotation was accompanied by an audible tendon snapping. Lower erythrocyte Zn levels and altered correlations between Ca2+, Mg, and Fe were found in TAO. Conclusion This whole body observational study has revealed axial deviations and body asymmetry as well as the phenomenon of moving toes in TAO. The most common finding was an arch-like displacement of the body, i.e. eccentric position, with foot inversion and head tilt

Literature in Focus L’étang - Mathilde Fontanet

CERN Document Server

2009-01-01

"The Pond" (L’étang), one of the eleven short stories that lends its name to the collection, is the tale of a forty-something woman who, alone and scared on a twenty-four-hour trip to the wilds of Yorkshire, makes a disturbing discovery along a meandering woodland pathway. The characters who haunt these pages - from the chronically shy young librarian or the divided twins, to the obsequious neighbour, the amnesiac aunt or the people encountered on a bus or at the hospital - are neither heroes nor heroines; they’re just people living ordinary lives, unremarkable destinies. These brief encounters, these snapshots of ordinary life, these snippets of existence made up of hesitant dialogue, insignificant gestures and feelings of love, whether acknowledged or not, are retold by Mathilde Fontanet with consummate artistry and restrained emotion. Ordinary they may be, but they leave an indelible impression on us. Wednesday 21 October,...

Zhen gan xi feng decoction, a traditional chinese herbal formula, for the treatment of essential hypertension: a systematic review of randomized controlled trials.

Science.gov (United States)

Xiong, Xingjiang; Yang, Xiaochen; Feng, Bo; Liu, Wei; Duan, Lian; Gao, Ao; Li, Haixia; Ma, Jizheng; Du, Xinliang; Li, Nan; Wang, Pengqian; Su, Kelei; Chu, Fuyong; Zhang, Guohao; Li, Xiaoke; Wang, Jie

2013-01-01

Objectives. To assess the clinical effectiveness and adverse effects of Zhen Gan Xi Feng Decoction (ZGXFD) for essential hypertension (EH). Methods. Five major electronic databases were searched up to August 2012 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of ZGXFD for EH reported in any language, with main outcome measure as blood pressure (BP). Results. Six randomized trials were included. Methodological quality of the trials was evaluated as generally low. Four trials compared prescriptions based on ZGXFD with antihypertensive drugs. Meta-analysis showed that ZGXFD was more effective in BP control and TCM syndrome and symptom differentiation (TCM-SSD) scores than antihypertensive drugs. Two trials compared the combination of modified ZGXFD plus antihypertensive drugs with antihypertensive drugs. Meta-analysis showed that there is significant beneficial effect on TCM-SSD scores. However, no significant effect on BP was found. The safety of ZGXFD is still uncertain. Conclusions. ZGXFD appears to be effective in improving blood pressure and hypertension-related symptoms for EH. However, the evidence remains weak due to poor methodological quality of the included studies. More rigorous trials are warranted to support their clinical use.

Da regra constitucional da acumulação de cargos de professor no ordenamento jurídico brasileiro

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Rocco Antonio Rangel Rosso Nelson

2016-09-01

Full Text Available Oconstituinte originário de 1988 fora preciso no que se refere ao regramento de exceção sobre o acúmulo de cargos públicos. Apesar dessa clareza solar, são incontáveis as interpretações quando do processo de subsunção no caso prático, digladiando-se os diversos entendimentos do que é praticado pela Administração Pública com que é decido no Poder Judiciário, além, é claro, das construções feitas pela doutrina. A pesquisa em tela, fazendo uso de uma metodologia de análise qualitativa, usando-se os métodos de abordagem hipotético-dedutivos de caráter descritivo e analítico, tem por linha de fundo analisar a temática sobre a regra constitucional permissa do acúmulo de cargos públicos, em específico, no que tange ao profissional da educação, o professor. Em especial, dar-se-á atenção a adequação do Parecer WM-9/98 da Advocacia Geral da União, utilizado com caráter impositivo pela Administração Pública Federal, e como orientação para Administração Pública Estadual e Municipal, com os requisitos do art. 37, XVI da Constituição Federal.

Cinema, história pública e educação: circularidade do conhecimento histórico em Xica da Silva (1976) e Chico Rei (1985)

OpenAIRE

Rodrigo de Almeida Ferreira

2014-01-01

No contexto da educaçãA tese Cinema, história pública e educação: circularidade do conhecimento histórico em Xica da Silva (1976) e Chico Rei (1985) propõe compreender o filme de gênero histórico no que tange a mediação, divulgação e produção do conhecimento histórico, tanto em espaço escolar, quanto não-escolar. Problematiza-se esse gênero fílmico para o saber histórico a partir da análise dos imaginários sociais presentes nos filmes, construídas na interface entre a historiografia e outros ...

Characterization of Thermophilic Halotolerant Aeribacillus pallidus TD1 from Tao Dam Hot Spring, Thailand

OpenAIRE

Yasawong, Montri; Areekit, Supatra; Pakpitchareon, Arda; Santiwatanakul, Somchai; Chansiri, Kosum

2011-01-01

The bacterial strain TD1 was isolated from Tao Dam hot spring in Thailand. Strain TD1 was Gram positive, rod-shaped, aerobic, motile, and endospore forming. The cell was 2.0–40 mm in length and about 0.4 mm in diameter. The optimum growth occurred at 55–60 °C and at pH 7–8. Strain TD1 was able to grow on medium containing up to 10% NaCl. The DNA G+C content was 38.9 mol%. The cellular fatty acid content was mainly C16:0, which comprised 25.04% of the total amount of cellular fatty acid. 16S r...

Intervenções para prevenir riscos psicossociais do trabalho de profissinais da saúde no Brasil e no Peru : revisão sistemática com base no scoping study

OpenAIRE

Luis Fidel Abregú Tueros

2016-01-01

O fator emergente transformado num problema global é o risco psicossocial do trabalho (RPT), por ter impacto maior nos profissionais da saúde, que por sua natureza, seriam mais vulneráveis, afetando quanto na saúde tanto em desempenho trabalhista. Sua importância, deve-se ao fato de serem menos tangíveis, de fato mais difícil de gerir e prevenir mediante abordagem proativa direcionadas ao origem, junto à sensibilização até políticas da gestão dos riscos. A pesquisa teve como objetivo comparar...

Identidades Politizadas no Reconhecimento Jurídico da Diferença: uma reflexão sobre o caso dos quilombos no Brasil

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Rebeca Campos Ferreira

2011-12-01

Full Text Available A realidade das comunidades remanescentes de quilombo no Brasil, sujeitos políticos que emergem a partir do Artigo 68 do ADCT/CF-88, permite pensar a política da identidade no acesso a direitos, no contexto do reconhecimento da diferença e do pluralismo jurídico. Trata-se da possibilidade de acesso a um direito de caráter coletivo, étnico e territorial, que remete à construção identitária, na medida em que o preceito constitucional pressupõe a emergência da identidade quilombola, em que pese a ressemantização do conceito, para fins da aplicabilidade legal. As prerrogativas constitucionais colocam o foco em marcadores étnicos e constituem paradoxo, no que tange à generalidade da lei frente às singularidades das situações, e ainda à fluidez de conceitos entre usos analíticos e nativos. A reflexão volta-se, portanto, à orientação política da identidade a partir do caso dos quilombos.

Effect of Li Adsorption on the Electronic and Hydrogen Storage Properties of Acenes: A Dispersion-Corrected TAO-DFT Study

OpenAIRE

Seenithurai, Sonai; Chai, Jeng-Da

2016-01-01

Due to the presence of strong static correlation effects and noncovalent interactions, accurate prediction of the electronic and hydrogen storage properties of Li-adsorbed acenes with n linearly fused benzene rings (n = 3 - 8) has been very challenging for conventional electronic structure methods. To meet the challenge, we study these properties using our recently developed thermally-assisted-occupation density functional theory (TAO-DFT) with dispersion corrections. In contrast to pure acen...

Directional Bias of TAO Daily Buoy Wind Vectors in the Central Equatorial Pacific Ocean from November 2008 to January 2010

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Ge Peng

2014-07-01

Full Text Available This article documents a systematic bias in surface wind directions between the TAO buoy measurements at 0°, 170°W and the ECMWF analysis and forecasts. This bias was of the order 10° and persisted from November 2008 to January 2010, which was consistent with a post-recovery calibration drift in the anemometer vane. Unfortunately, the calibration drift was too time-variant to be used to correct the data so the quality flag for this deployment was adjusted to reflect low data quality. The primary purpose of this paper is to inform users in the modelling and remote-sensing community about this systematic, persistent wind directional bias, which will allow users to make an educated decision on using the data and be aware of its potential impact to their downstream product quality. The uncovering of this bias and its source demonstrates the importance of continuous scientific oversight and effective user-data provider communication in stewarding scientific data. It also suggests the need for improvement in the ability of buoy data quality control procedures of the TAO and ECMWF systems to detect future wind directional systematic biases such as the one described here.

INTEGRAÇÃO COMUNITÁRIA ATRAVÉS DA EDUCAÇÃO COOPERATIVA: OS PROGRAMAS DE ENSINO E PESQUISA DA UNESP/FFC

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Rosângela Formentini Caldas

2014-06-01

Full Text Available O processo de ensino-aprendizagem se valoriza diante das políticas educacionais e configura-se no eixo da extensão universitária ao idealizar uma sociedade que cresce e desponta na produção de informação e conhecimento. A proposta desta pesquisa verificou a integração dos objetivos de programas institucionais que priorizam a valoração da aprendizagem e procurou identificar como incidem no processo de ensino das instituições de ensino superior. O objetivo geral analisou as atividades desenvolvidas pelo grupo de alunos que compõem o Programa de Educação Tutorial (PET como recurso da representação do conhecimento de alunos da graduação na integração do ensino e da aprendizagem entre universidades. Para tanto, estabelece parâmetros indicativos da educação cooperativa existente na prática pedagógica premente em programas como o do Centro de Estudos e Práticas Pedagógicas (CENEPP. A metodologia investigativa estabeleceu parâmetros indicativos da representação do conhecimento na abordagem metodológica Survey que foi utilizada na coleta de dados. Como resultados da pesquisa percebeu-se que o programa PET se fundamenta na atividade da prática do ensino no que tange uma educação cooperativa como ponto de partida para a produção do conhecimento e a integração da universidade a uma sociedade verdadeiramente democrática. Possui forte impacto nas ações que integra junto à sua comunidade de atuação. Requer assim, a interação ao estímulo do ensino e criatividade dos alunos a fim de divulgar e apoiar a valorização da pesquisa e dos resultados investigativos existentes entre docentes, pesquisadores e comunidade.

Cooperação Jurídica Internacional e Direitos Humanos: para além da interação rumo à harmonização

OpenAIRE

Iensue, Geziela; Universidade Federal de Mato Grosso do Sul - UFMS; Coimbra de Carvalho, Luciani; Universidade Federal de Mato Grosso do Sul - UFMS

2016-01-01

O tema da cooperação jurídica internacional é um capítulo extremamente relevante do estudo do Direito Internacional Privado. No entanto, o excessivo enfoque nas ordens jurídicas nacionais e a falta de um arcabouço normativo que estabeleça regras de atuação comuns aos Estados-partes no que tange à cooperação jurídica internacional impede a superação da mera interação rumo à harmonização das relações internacionais. O presente artigo propõe-se a apresentar, a partir do método dedutivo, uma comp...

Effects of Sohamhyoong-Tang on Ovalbumin-Induced Allergic Reaction in BALB/c Mice

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So Hyun Jo

2016-01-01

Full Text Available IgE-mediated mast cell degranulation and excessive Th2 cells activation are major features of various allergic diseases. Sohamhyoong-tang has been reported to have anti-inflammatory and antibacterial effects. In this study, we investigated the inhibitory effect of Sohamhyoong-tang extract (SHHTE on allergic symptoms and inflammatory responses in ovalbumin- (OVA- sensitized BALB/c mice. The mice were sensitized with OVA and alum at 2-week intervals and then orally given SHHTE for 13 days followed by intradermal OVA injection. Administration of SHHTE significantly reduced edema formation and inflammatory-cell infiltration in ear tissues. Total and OVA-specific IgEs as well as proinflammatory cytokine TNF-α and Th2-associated cytokine IL-4 levels were lower in the SHHTE-treated group than in the vehicle. SHHTE treatment significantly suppressed both mRNA and protein levels of IL-4 and IL-5 in OVA-stimulated splenocytes. SHHTE decreased Th1 (IFN-γ and Th17 (IL-17a cytokine mRNA expression but increased Treg cytokines (IL-10 and TGF-β1. Moreover, SHHTE significantly inhibited degranulation of RBL-2H3 cell line in a dose-dependent manner. Thus, SHHTE efficiently inhibited the allergic symptoms in an OVA-sensitized mouse model and its action may correlate with the suppression of IgE production by increasing IL-10 and TGF-β1, which can limit the function of other T helper cells and prevent the release of inflammatory mediators from mast cells. These results suggest that SHHTE could be a therapeutic agent for treating various allergic diseases.

Effect of Li Termination on the Electronic and Hydrogen Storage Properties of Linear Carbon Chains: A TAO-DFT Study

OpenAIRE

Seenithurai, Sonai; Chai, Jeng-Da

2017-01-01

Accurate prediction of the electronic and hydrogen storage properties of linear carbon chains (C n ) and Li-terminated linear carbon chains (Li2C n ), with n carbon atoms (n?=?5?10), has been very challenging for traditional electronic structure methods, due to the presence of strong static correlation effects. To meet the challenge, we study these properties using our newly developed thermally-assisted-occupation density functional theory (TAO-DFT), a very efficient electronic structure meth...

A PERCEPÇÃO DOS BENEFÍCIOS PREVIDENCIÁRIOS DA PENSÃO POR MORTE E AUXÍLIO RECLUSÃO NOS CASOS DE CASAIS HOMOAFETIVOS

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Natalia Brito Silva

2014-11-01

Full Text Available Este trabalho apresenta os avançosno campo do Direito Previdenciário no que tange aos direitos e garantias dos casais homoafetivos. Dada a omissão legislativa,visa demonstrar como tem sido a construção jurisprudencial que abarca os direitos à percepção dos benefícios previdenciários da pensão por morte e auxilio reclusão em casos de união homoafetiva e quais as dificuldades enfrentadas no campo prático. Considerando que as relações entre pessoas do mesmo sexo datam do início da sociedade, o intuito deste trabalho não é discutir a legalidade ou não destas relações, mas sim explanar sobre a constante evolução da jurisprudência que abarca as pessoas que vivem uma relação homoafetiva e fazem jus a um tratamento digno, ponderando os princípios da dignidade da pessoa humana e da isonomia.

Simultaneous use of traditional Chinese medicine (Si-Ni-Tang to treat septic shock patients: study protocol for a randomized controlled trial

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Wu Shin-Hwar

2011-08-01

Full Text Available Abstract Background Even though there are continually upgraded recommendations for managing sepsis, such as "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock", mortality is still high. Si-Ni-Tang, a remedy documented in Shanghan Lun, a medical collection from ancient China, is used for treating patients with sepsis and septic shock. Using a well-designed clinical trial, we are eager to survey the effectiveness of the concurrent use of this remedy in restoring these patients' hemodynamic status, or "Yang Qi". Methods/Design Patients admitted to our medical intensive care units with the diagnosis of septic shock, defined as persistent hypotension induced by sepsis despite adequate fluid resuscitation, are eligible for participation. The inclusion criteria include: age from 20 to 85 years, conditions meeting the definition of septic shock, use of vasopressors within 24 hours of entering the study, and use of a nasogastric tube for feeding. The enrolled patients are randomly allocated either to the Si-Ni-Tang group or the placebo group. The prescription of the trial drugs (Si-Ni-Tang/placebo is 2.25 grams 4 times a day for 7 days or till shock reversal (if shock reversal occurs in less than 7 days. Data, including duration of vasopressor infusion, gender, age, co-morbidities, APACHE II score, predicted mortality, ICU mortality, ICU length of stay, hospital mortality, hospital length of stay, source of sepsis, and culture results, are collected for the following analysis. Discussion Si-Ni-Tang is composed of processed Zingiber officinale, Glycyrrhiza uralensis, and Aconitum carmichaeli. Zingiber officinale and Glycyrrhiza uralensis are found to have the ability to reduce pro-inflammatory cytokine production, to inhibit lipopolisaccharide-induced macrophage activation and function, and to lessen the bacterial load and suppress acute and chronic inflammation. Aconitum carmichaeli is known to have

Fighting Swaying Imbalances of Powers: The Transformation of Spiritual Freedom in Tang Tales into Individual Freedom in Hou Hsiao-hsien’s The Assassin

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Frank Kraushaar

2018-03-01

Full Text Available The appearance of Hou Hsiao-hsien’s 侯孝賢 film The Assassin in 2015 and its distinction the same year with the Best Director’s award at the film festival in Cannes has launched an avalanche of confused and confusing reviews in print-media and on the internet. This partly may have been due to the gap between expectations the film’s attribution to the wuxia genre generated in the public and what actually Hou expects from his audience. Despite an unmistakable historical contextualisation at the heart of power-struggling between the Tang imperial court and the ruling house of Weibo, a state that manages to assert its de facto independence behind a diaphanous diplomatic veil of loyalty, the story of the young female assassin Nie Yinniang develops into a sphere of its own, which seems to extend beyond the confines of history and strongly suggests a freedom unspeakable within the intellectual parameter of Tang. This paper traces back the film’s narrative based on Tang dynasty tales and its cinematic language, and arrives at an interpretation related to contemporary social and political topics such as the female/male body and violence. It also touches upon the cross-strait relations’ issues and the “Western” idea of freedom expressed in an apparently traditional Chinese narrative context.

Physical profile data collected in the Equatorial Pacific during cruises to service the TAO array, a network of deep ocean moored buoys, from 2007-04-07 to the present

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — As part of the Tropical Atmosphere Ocean (TAO) Program, the National Data Buoy Center (NDBC) was responsible for the at-sea collection, quality control and...

The Study on the Composition of Yongdamsagan-tang(龍膽瀉肝湯’s Essential Oil Obtained by Supercritical Carbon Dioxide Extraction

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Shin Min-Seop

2008-03-01

Full Text Available Objectives : This study was performed to analyze the effective components of essential oil obtained from Yongdamsagan-tang, which has been efficacious against leukorrhea in gynecologic diseases. Methods : I obtained the essential oils of Yongdamsagan-tang by hydrodistillation extraction method and supercritical fluid extraction(SFE method, and then I analyzed those by GC/MS(Gas Chromatography/Mass Spectrum. Results : 1. The optimum SFE(Supercritical Fluid Extraction condition was obtained in the following experiment conditions: pressure 200atm, temperature 45℃, duration of extraction 25minutes. 2. With GC(Gas Chromatography and GC/MS(Gas Chromato- graphy/Mass Spectrum analysis, I identified 37 compounds in the Yongdamsagan-tang's essential oil obtained through the SFE method. The main compounds were as follows : 3-Methyl-but-2-enoic acid,2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H -pyrano[3,2-g]chromen-3-yl ester(49.81 %, (Z-6-Pentadecen-1 -ol(3.19%, (--Spathulenol(2.40%. 3. I identified 4 compounds in the Yongdamsagan-tang's essential oil obtained through the hydrodistillation method. The main compounds were as follows : 3-Methyl-but-2-enoic acid, 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl ester(2.61%. 4. 3 - Methy l - but - 2 - enoic acid, 2, 2 - dimethyl - 8 - oxo - 3, 4 - dihydro - 2H, 8H - pyrano[3, 2 - g] chromen - 3 - yl ester, all were identified in both the SFE method and the hydrodistillation method, but the others were not identified in common. 5. I also conducted an additional test in order to examine the essential oil's antimicrobial action against bacteria. Both MIC(Minimum Inhibitory Concentrations and MBC(Minimum Bactericidal Concentrations were 0.125㎎/㎖ against N. meningitidis, however MIC and MBC were 1.0㎎/㎖ in antimicrobial action against 12 different genera of bacteria.

Variations de la température de l'eau des étangs en période froide à ...

African Journals Online (AJOL)

SARAH

30 juin 2015 ... Conclusion et application : La mise en évidence de la courbe de variation de température en période froide à Lubumbashi est cruciale pour la mise en place des systèmes de .... niloticus) et le poisson-chat africain (Clarias ngamensis et Clarias gariepinus). Les étangs dont la profondeur varie entre 120 et ...

Magnetotelluric data, Taos Plateau Volcanic Field, New Mexico

Science.gov (United States)

Ailes, Chad E.; Rodriguez, Brian D.

2010-01-01

The population of the San Luis Basin region of northern New Mexico is growing. Water shortfalls could have serious consequences. Future growth and land management in the region depend on accurate assessment and protection of the region's groundwater resources. An important issue in managing the groundwater resources is a better understanding of the hydrogeology of the Santa Fe Group and the nature of the sedimentary deposits that fill the Rio Grande rift, which contain the principal groundwater aquifers. The shallow unconfined aquifer and the deeper confined Santa Fe Group aquifer in the San Luis Basin are the main sources of municipal water for the region. The U.S. Geological Survey (USGS) is conducting a series of multidisciplinary studies of the San Luis Basin. Detailed geologic mapping, high-resolution airborne magnetic surveys, gravity surveys, an electromagnetic survey called magnetotellurics (MT), and hydrologic and lithologic data are being used to better understand the aquifers. This report describes a regional east-west MT sounding profile acquired in late July 2009 across the Taos Plateau Volcanic Field where drillhole data are sparse. Resistivity modeling of the MT data can be used to help map changes in electrical resistivity with depths that are related to differences in rock types. These various rock types help control the properties of aquifers. The purpose of this report is to release the MT sounding data collected along the east-west profile. No interpretation of the data is included.

THE TAOS PROJECT: UPPER BOUNDS ON THE POPULATION OF SMALL KUIPER BELT OBJECTS AND TESTS OF MODELS OF FORMATION AND EVOLUTION OF THE OUTER SOLAR SYSTEM

International Nuclear Information System (INIS)

Bianco, F. B.; Zhang, Z.-W.; King, S.-K.; Wang, J.-H.; Lee, T.; Lin, H.-C.; Lehner, M. J.; Mondal, S.; Giammarco, J.; Holman, M. J.; Alcock, C.; Coehlo, N. K.; Axelrod, T.; Byun, Y.-I.; Kim, D.-W.; Chen, W. P.; Cook, K. H.; Dave, R.; De Pater, I.; Lissauer, J. J.

2010-01-01

We have analyzed the first 3.75 years of data from the Taiwanese American Occultation Survey (TAOS). TAOS monitors bright stars to search for occultations by Kuiper Belt objects (KBOs). This data set comprises 5 x 10 5 star hours of multi-telescope photometric data taken at 4 or 5 Hz. No events consistent with KBO occultations were found in this data set. We compute the number of events expected for the Kuiper Belt formation and evolution models of Pan and Sari, Kenyon and Bromley, Benavidez and Campo Bagatin, and Fraser. A comparison with the upper limits we derive from our data constrains the parameter space of these models. This is the first detailed comparison of models of the KBO size distribution with data from an occultation survey. Our results suggest that the KBO population is composed of objects with low internal strength and that planetary migration played a role in the shaping of the size distribution.

Concentration serum cortisol data from experimental studies of Yellow Tang fish (Zebrasoma flavescens) from 2011-07-10 to 2011-11-10 (NODC Accession 0125562)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This archival package contains laboratory experiment data that were collected to examine the effects of venting and decompression on Yellow Tang (Zebrasoma...

O murmúrio do tangível - A semântica tátil na sintaxe da superfície

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Susana Maria Pires

2017-10-01

Full Text Available Poder-se-ia descrever a perceção tátil como a experiência de presença sem representação. Esta afirmação implicaria, no domínio das artes visuais, um discurso que, simultaneamente, afeta e se desvincula da problemática da ontologia da imagem e dos movimentos da linguagem. O sentido do tato é aquele que nos dá informação mais direta, real e concreta da superfície e corpo da matéria, no entanto a sua sintaxe é feita por relações abstratas. As qualidades e funções haptológicas dentro de cada cultura, o seu papel na comunicação e a forma como estas são afetadas pela tecnologia têm vindo a ganhar destaque nas criações artísticas contemporâneas, na academia e na sociedade em geral. Desdobrando o léxico do tato em sentido temático e função operativa, este artigo realiza uma breve trajetória ancorada na poética do tato no contexto das artes visuais. Paralelamente, indaga acerca da reciprocidade produtiva entre um pensamento centrado na funcionalidade tátil e o desenvolvimento de materiais interativos. ABSTRACT Tactile perception could be described as the experience of presence without representation. This point may not have a good framework in the issues of the image and language. The sense of touch is which gives us the truest information of real surfaces, still its syntax is made by abstract relations. The basic quality or function of touch within culture, the role of touch in communication and the ways in which touch is affected by technology are in our days an expanding field of research. Distinguishing touch between thematic sense and operating function, this paper makes a brief trajectory anchored in the poetics of touch in visual arts. Will be investigated simultaneously the relation between the touch thought and the smart textiles. KEYWORDS Touch, tangible, surface, contact, smart textiles.

Identification of metabolites in human and rat urine after oral administration of Xiao-Qing-Long-Tang granule using ultra high performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry.

Science.gov (United States)

Zhou, Lei; Zhang, Qiang; Qi, Wen; Yan, Shuai; Qu, Jialin; Makino, Toshiaki; Yuan, Dan

2017-09-01

Xiao-Qing-Long-Tang is a traditional Chinese formula used for the treatment of cold syndrome, bronchitis, and nasal allergies for thousands of years. However, the in vivo integrated metabolism of its multiple components and the active chemical constituents of Xiao-Qing-Long-Tang remain unknown. In this study, a method using ultra high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry was established for the detection and identification of the metabolites in human and rat urine after oral administration of Xiao-Qing-Long-Tang. A total of 19 compounds were detected or tentatively identified in human urine samples, including eight prototypes and 11 metabolites. Also, a total of 50 compounds were detected or tentatively identified in rat urine samples, including 15 prototypes and 35 metabolites detected with either a highly sensitive extracted ion chromatogram method or the MS E determination using Mass Fragment software. Our results indicated that phase Ⅱ reactions (e.g. glucuronidation and sulfation) were the main metabolic pathways of flavones, while phase I reactions (e.g. demethylation and hydroxylation) were the major metabolic reaction for alkaloids, lignans, and ginger essential oil. This investigation provided important structural information on the metabolism of Xiao-Qing-Long-Tang and provided evidence to obtain a more comprehensive metabolic profile. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Tang-Luo-Ning Improves Mitochondrial Antioxidase Activity in Dorsal Root Ganglia of Diabetic Rats: A Proteomics Study

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Taojing Zhang

2017-01-01

Full Text Available Tang-luo-ning (TLN is a traditional Chinese herbal recipe for treating diabetic peripheral neuropathy (DPN. In this study, we investigated mitochondrial protein profiles in a diabetic rat model and explored the potential protective effect of TLN. Diabetic rats were established by injection of streptozocin (STZ and divided into model, alpha lipoic acid (ALA, and TLN groups. Mitochondrial proteins were isolated from dorsal root ganglia and proteomic analysis was used to quantify the differentially expressed proteins. Tang-luo-ning mitigated STZ-induced diabetic symptoms and blood glucose level, including response time to cold or hot stimulation and nerve conductive velocity. As compared to the normal, there were 388 differentially expressed proteins in the TLN group, 445 in ALA group, and 451 in model group. As compared to the model group, there were 275 differential proteins in TLN group and 251 in ALA group. As compared to model group, mitochondrial complex III was significantly decreased, while glutathione peroxidase and peroxidase were increased in TLN group. When compared with ALA group, the mitochondrial complex III was increased, and mitochondrial complex IV was decreased in TLN group. Together, TLN should have a strong antioxidative activity, which appears to be modulated through regulation of respiratory complexes and antioxidases.

Improving cachectic symptoms and immune strength of tumour-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang.

Science.gov (United States)

Wang, Hang; Chan, Yi-Lin; Li, Tsung-Lin; Wu, Chang-Jer

2012-05-01

Cancer cachexia is characterised by the loss of body mass and directly compromises immune response and the quality of life of cancer patients. In the present study, we set out to investigate the role of Chinese herbs as anticancer medicines and/or chemotherapeutic adjuvants to increase therapeutic efficacy and/or ameliorate given side-effects in animal model. Twelve kinds of herbs were chosen from the ingredients of major Chinese herbal medicines, and their effects on the antioxidant activity were investigated. To obtain the anticancer effects of 5-fluorouracil (5-FU) when consumed with minimal side-effects, we investigated the combination effect of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang that may enhance the anticancer activity of 5-FU on subcutaneous tumour growth in C57BL/6 mice challenged with Lewis lung carcinoma cells. Qing-Shu-Yi-Qi-Tang, a multiple-component herbal extract, was shown to have high anti-oxidation activity, while S. baicalensis (Chinese skullcap) was demonstrated to have high tumour-growth inhibition activity. Thus, S. baicalensis and Qing-Shu-Yi-Qi-Tang were evaluated for their combinaton effects on the cancer-induced cachectic murine upon receiving 5-FU chemotherapy. As a result, tumour masses and losses of carcass and/or gastrocnemius muscle were found to be significantly decreased. This combination otherwise increased both Th1/Th2 ratio and NK cytotoxicity. In the mice receiving with or without 5-FU, the serum levels of monocyte chemoattractant protein-1 (MCP-1) increased by all means but otherwise decreased when the herbal combination was administrated. Additionally, the expressions of nuclear factor-kappa B (NF-κB) and muscle RING finger protein-1 (MuRF-1) decreased in the gastrocnemius muscle when the herbal combination was applied. Our results revealed that the combination of S. baicalensis and Qing-Shu-Yi-Qi-Tang is able to ameliorate cachectic symptoms and positively stimulate anti-tumour immunity while undergoing

A imagem de profissões da saúde sob a perspectiva do marketing

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Claudiney Luís Ferreira

2015-02-01

Full Text Available O objetivo deste trabalho foi comparar a percepção da imagem da profissão de farmacêutico com outras profissões da área da saúde, sendo a imagem analisada em quatro dimensões: cognitiva, funcional, simbólica e emocional. Foi realizada uma pesquisa qualitativa por meio de entrevistas envolvendo diversos stakeholders para avaliar a imagem do farmacêutico e análise de estudos de imagem da profissão de fisioterapia, fonoaudiologia e psicologia. Os resultados indicam que para a dimensão funcional não há uma imagem específica do farmacêutico quanto aos aspectos tangíveis, quando comparado às demais profissões pesquisadas. Para a dimensão cognitiva, os resultados apontam que não existe uma percepção clara do que consistem as profissões e nem de suas atribuições. Na dimensão emocional a imagem das profissões diz respeito às emoções evocadas antes, durante e após a prestação de um serviço com predominância para as emoções positivas. A dimensão simbólica mostrou que as profissões são representações assistencialistas. Para a sociedade somente o médico é visto como referência quando se trata do cuidado à saúde.

A Construção dos Fundamentos Conceituais da Economia Solidária

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Dyego de Oliveira Arruda

2013-12-01

Full Text Available http://dx.doi.org/10.5007/2175-7984.2013v12n25p99 O presente trabalho tem como objetivo geral lançar luz acerca dos fundamentos basilares da economia solidária, situando-a no que tange aos aspectos históricos, sociológicos e até mesmo econômicos que lhe são pertinentes. Entende-se que a economia solidária – como quadro referencial das ciências sociais – erigiu-se numa perspectiva de adaptação/negação dos desígnios acumulativos e excludentes do modo de produção capitalista, numa tentativa de humanização deste sistema. Logo, todo o quadro analítico da economia solidária foi construído neste trabalho a partir desta perspectiva de adaptação/negação dos fundamentos basilares do sistema capitalista. Trata-se, portanto, de um artigo decorrente de uma pesquisa essencialmente qualitativa, de caráter descritivo e exploratório – sobretudo por conta da contemporaneidade do tema. Entende-se que, mediante ao levantamento das informações, urgem pesquisas acerca das próprias práticas de economia solidária contemporâneas, situando-as no seio das políticas públicas, bem como no âmbito da evolução da economia solidária enquanto movimento organizado.

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

International Nuclear Information System (INIS)

Jang, Jong Sik; Kim, Sung Ho

2008-01-01

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

Energy Technology Data Exchange (ETDEWEB)

Jang, Jong Sik [Kyungpook National University, Daegu (Korea, Republic of); Kim, Sung Ho [Chonnam National University, Gwangju (Korea, Republic of)

2008-09-15

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients.

Plano de classificação de documentos arquivísticos e a teoria da classificação: uma interlocução entre domínios do conhecimento

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Elaine Rosa Rios

Full Text Available Estudo sobre os princípios teóricos e metodológicos que envolvem a elaboração dos planos de classificação documental em arquivos, com ênfase no conhecimento do contexto, no qual se insere a instituição. Os princípios da teoria da classificação que regem a construção de linguagens documentárias e, em especial, as notacionais, no âmbito da organização do conhecimento, devem fundamentar a construção dos planos de classificação para documentos arquivísticos. Conclui que a Arquivologia deve aprofundar o diálogo com outras áreas do conhecimento, especialmente a Ciência da Informação, no que tange à análise e a representação do conhecimento.

Espaço, imagem e memória: adensamento dos conteúdos coletivos à materialidade da cidade

OpenAIRE

Zaiatz Crestani, Andrei Mikhail; Martins de Araújo Klein, Regina Maria

2017-01-01

Resumo As relações socioespaciais conferem conteúdo ao espaço urbano e imprimem no tempo significados que se adensam materialmente. No percurso temporal-cronológico, relações tangíveis e intangíveis constroem a paisagem urbana tecendo memórias coletivas, que se endereçam a lugares da cidade. Neste trabalho, discute-se o processo de assentamento de significados e memória coletiva nos espaços urbanos e sua relação tanto com ações de gestão quanto com a apropriação populacional. O objeto empíric...

Physical profile and meteorological data from CTD casts during cruises to service the TAO/TRITON buoys in the equatorial Pacific from 02 March 2002 to 22 November 2002 (NODC Accession 0000945)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Physical profile data and meteorological data were collected from CTD casts in the equatorial Pacific Ocean during cruises to to service the TAO/TRITON buoy array....

Cuidar integral da equipe multiprofissional: discurso de mulheres em pré-operatório de mastectomia

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Karla Tamyres Santos do Nascimento

2014-09-01

Full Text Available Objetivo: Investigar a atuação da equipe multiprofissional, no que tange a preparação de mulheres em pré-operatório de mastectomia. Métodos: Trata-se de uma pesquisa exploratória com abordagem qualitativa, realizada na clínica cirúrgica de um hospital público, em João Pessoa - PB. A amostra foi composta por sete mulheres que iriam se submeter à mastectomia. A coleta de dados foi iniciada após parecer favorável do Comitê de Ética em Pesquisa nº 751/10 e CAAE nº 0578.0.126.000-10, no período de fevereiro a maio de 2011, por meio da técnica de entrevista gravada. Resultados: Os dados obtidos foram analisados mediante a técnica do Discurso do sujeito coletivo, gerando quatro ideias centrais, destacando a atuação da equipe multiprofissional, contemplando orientações pertinentes ao procedimento cirúrgico, pré-operatórias, apoio psicológico, espiritual e nutricional. Conclusão: Conclui-se que existe a necessidade de uma maior integração da equipe multiprofissional, para propiciar melhor assistência à mulher no período pré-operatório de mastectomia.

Physical profile data collected in the Equatorial Pacific during cruises to service the TAO/TRITON array, a network of deep ocean moored buoys, February 23 - December 16, 2005 (NODC Accession 0002644)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — During 2005, CTD data were collected in the equatorial Pacific Ocean during cruises to service the TAO/TRITON array, a network of deep ocean moored buoys to support...

Cola, plágio e outras práticas acadêmicas desonestas: um estudo quantitativo-descritivo sobre o comportamento de alunos de graduação e pós-graduação da área de negócios

OpenAIRE

Veludo-de-Oliveira,Tânia Modesto; Aguiar,Fernando Henrique Oliveira de; Queiroz,Josimeire Pessoa de; Barrichello,Alcides

2014-01-01

As atividades fraudulentas no mundo corporativo têm sido motivo crescente de preocupação da sociedade e podem estar associadas a falhas na formação educacional dos gestores. Este estudo tem por objetivo analisar o comportamento dos alunos de cursos relacionados à área de negócios no que tange a práticas acadêmicas desonestas, como cola e plágio; a base teórica adotada para o desenvolvimento da pesquisa foi o trabalho de Chapman, Davis, Toy e Wright (2004). O escopo teórico do estudo versa sob...

Huangqin-Tang and Ingredients in Modulating the Pathogenesis of Ulcerative Colitis.

Science.gov (United States)

Wang, Chunyan; Tang, Xudong; Zhang, Li

2017-01-01

Ulcerative colitis (UC) is the most common inflammatory bowel disease worldwide. Current therapies in UC cause limitations, and herb medicine provides an important choice for UC treatment. Huangqin-Tang (HQT) is a well-known classical traditional Chinese herbal formula and has been used in China for thousands of years. A large number of pharmacological studies demonstrated HQT and its ingredients to be effective in treating UC. Though the therapeutic effect has been evaluated, comprehensive up-to-date reviews in this field are not yet available. Here we aim to review our current understanding of HQT and its ingredients in treating UC and how the agents modulate the main pathogenesis of the disease, including the intestinal environment, immune imbalance, inflammatory pathways, and oxidative stress. The summary on this issue may provide better understanding of HQT and its ingredients in treating UC and possibly help in promoting its clinical application.

Estudo Macro e Microscópico da Placenta de Termo de Capivara (Hydrochaeris hydrochaeris - Carleton, M. D. 1984)

OpenAIRE

Rosa Helena dos Santos Ferraz

2001-01-01

O habitat natural da capivara é a América Central e do Sul, em áreas que vão desde o Panamá até a Argentina, o que inclui a região Andina. Estes animais são herbívoros, diurnos, semi-aquáticos, gregários e dóceis; eles formam grandes rebanhos e são potencialmente importantes para: a produção de carne de ótima qualidade, couro e óleo, amplamente utilizado na medicina popular. Apesar de seu presuntivo valor econômico, estes animais foram até o momento pobremente estudados, mesmo no que tange às...

Synthesis, characterization, and photoactivity of InTaO4 and In0.9Ni0.1TaO4 thin films prepared by electron evaporation

International Nuclear Information System (INIS)

Rico, V. J.; Frutos, F.; Yubero, F.; Espinos, J. P.; Gonzales-Elipe, A. R.

2010-01-01

InTaO 4 and In 0.9 Ni 0.1 TaO 4 thin films have been prepared by electron evaporation of successive layers of the single oxide components and posterior annealing at T>800 deg. C. The annealed thin films presented the monoclinic crystallographic structure typical of these mixed oxides. The electrical and optical behaviors of the films, assessed by C-V measurements, surface conductivity as a function of temperature, and UV-vis absorption spectroscopy, indicate that these oxides are wide band gap semiconductors with a variable dielectric constant depending on the annealing conditions. By reflection electron energy loss spectroscopy some electronic states have been found in the gap at an energy that is compatible with the activation energy deduced from the conductivity versus 1/T plots for these oxides. The photoactivity of these materials has been assessed by looking to the evolution of the wetting contact angle as a function of the irradiation time. All the films became superhydrophilic when irradiated with UV light, while the In 0.9 Ni 0.1 TaO 4 thin films also presented a small partial decrease in wetting angle when irradiated with visible photons.

Acesso ao cuidado na Estratégia Saúde da Família: equilíbrio entre demanda espontânea e prevenção/promoção da saúde

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Armando Henrique Norman

2015-03-01

Full Text Available Este artigo propõe algumas diretrizes para a organização do trabalho na Atenção Primária à Saúde (APS e na Estratégia Saúde da Família (ESF, relacionadas aos desafios de prover acesso e equilibrar no cotidiano dos serviços ações de prevenção de agravos e promoção da saúde com o cuidado ao adoecimento. Primeiramente, apresenta algumas ideias específicas sobre a importância do acesso para a qualidade dos serviços de saúde, seguidas de uma crítica sintética - fundamentada nos conceitos de Geoffrey Rose - à estratégia preventiva de alto risco, que tem tido alto impacto na organização das rotinas assistenciais. A seguir, contextualiza a promoção da saúde relacionada ao cuidado individual na APS/ESF, discutindo o potencial sinérgico do cuidado e da promoção da saúde, em suas dimensões individuais e coletivas, para transcender o modelo biomédico/mecanicista. Finalmente, apoiado nos tópicos anteriores, no que tange aos seus desdobramentos operacionais e utilizando um exemplo concreto, propõe algumas diretrizes para a organização do trabalho e das agendas de médicos e enfermeiros da ESF, de modo a viabilizar equilíbrio e sinergia entre acesso ao cuidado e prevenção/promoção, com vistas ao fortalecimento da ESF como coordenadora local do cuidado e principal porta de entrada do Sistema Único de Saúde.

Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

OpenAIRE

Chia-Hao Yeh; Christof K. Arnold; Yen-Hui Chen; Jung-Nein Lai

2011-01-01

Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat receive...

Effects of Gui Zhi Ma Huang Ge Ban Tang on the TLR7 Pathway in Influenza Virus Infected Mouse Lungs in a Cold Environment.

Science.gov (United States)

Qin, Hong-Qiong; Shi, Shan-Shan; Fu, Ying-Jie; Yan, Yu-Qi; Wu, Sha; Tang, Xiao-Long; Chen, Xiao-Yin; Hou, Guang-Hui; Jiang, Zhen-You

2018-01-01

We wished to investigate the effects of the traditional Chinese medicine Gui Zhi Ma Huang Ge Ban Tang on controlling influenza A virus (IAV) infection and improving inflammation in mouse lungs. Mice were maintained in normal and cold environments and infected with IAV by intranasal application, respectively. Real-time quantitative polymerase chain reaction was used to measure mRNA expression of TLR7, myeloid differentiation primary response 88 (MyD88), and nuclear factor-kappa B (NF- κ B)p65 in the TLR7 signaling pathway and virus replication in lungs. Western blotting was used to measure expression levels of TLR7, MyD88, and NF- κ B p65 proteins. Flow cytometry was used to detect the proportion of T-helper (Th)1/Th2 and Th17/T-regulatory (Treg) cells. Application of Gui Zhi Ma Huang Ge Ban Tang in influenza-infected mice in a cold environment showed (i) downregulation of TLR7, MyD88, and NF- κ Bp65; (ii) inhibition of transcriptional activities of promoters coding for TLR7, MyD88, and NF- κ Bp65; (iii) reduction in the proportion of Th1/Th2 and Th17/Treg cells. Gui Zhi Ma Huang Ge Ban Tang had a good therapeutic effect on mice infected with IAV, especially in the cold environment. It could reduce lung inflammation in mice significantly and elicit an anti-influenza effect by downregulating expression of the key factors in TLR7 signaling pathway.

Optimization of high pressure machine decocting process for Dachengqi Tang using HPLC fingerprints combined with the Box–Behnken experimental design

OpenAIRE

Xie, Rui-Fang; Shi, Zhi-Na; Li, Zhi-Cheng; Chen, Pei-Pei; Li, Yi-Min; Zhou, Xin

2014-01-01

Using Dachengqi Tang (DCQT) as a model, high performance liquid chromatography (HPLC) fingerprints were applied to optimize machine extracting process with the Box–Behnken experimental design. HPLC fingerprints were carried out to investigate the chemical ingredients of DCQT; synthetic weighing method based on analytic hierarchy process (AHP) and criteria importance through intercriteria correlation (CRITIC) was performed to calculate synthetic scores of fingerprints; using the mark ingredien...

Panorama da estrutura presidiária brasileira

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Renata de Oliveira Cartaxo

2013-06-01

Full Text Available Objetivo: Descrever, a partir do Sistema Integrado de Informações Penitenciárias – Infopen, aspectos da estrutura prisional nacional, características dos apenados e perfil dos profissionais existentes para garantir o preceito constitucional de assistência à saúde. Métodos: Estudo descritivo, de base documental, realizado a partir de dados secundários disponíveis no Sistema Integrado de Informações Penitenciárias, no qual analisaram-se a estrutura carcerária brasileira, o perfil do apenado no que tange a características pessoais e do crime cometido, e os profissionais envolvidos na assistência à saúde. Resultados: Constata-se que existem 298.275 vagas, ocupadas por 496.251 presos nos 1.857 estabelecimentos penais. No tocante ao perfil dos presos, verifica-se que 92,3% (461.444 são do sexo masculino, na faixa etária entre 18 e 24 anos (25,6% - 126.929, da cor parda (36,7% - 82.354, comensino fundamental incompleto (40,7% - 201.938, que cometeram, principalmente, o crime de tráfico de entorpecentes (23,5% - 100.648. Quanto à composição da equipe de assistência à saúde, evidencia-se um total de 5.132 profissionais registrados no sistema. Conclusão: Constata-se, a partir do sistema integrado de informações penitenciárias, que a estrutura carcerária brasileira se caracteriza por apresentar um déficit de vagas, ocasionada pelasuperlotação e/ou saturação dos estabelecimentos existentes, o que dificulta, em especial, a garantia do atendimento às necessidades de saúde dos apenados.

A diversificação da estrutura produtiva no Brasil: observações preliminares

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Jucélio Kretzer

2015-08-01

Full Text Available RESUMO Este trabalho tem como objetivo examinar a extensão da diversificação das operações produtivas no Brasil, de 2006 a 2010. Em 2007, o IBGE passou a adotar a versão 2.0 da CNAE, divulgando novas informações estatísticas de unidades ativas, em especial referentes às variáveis derivadas "empresa não diversificada" e "empresa diversificada". Conclui-se que a maioria das empresas do país apresenta um baixo nível de diversificação; a maioria das empresas brasileiras é "especializada" em suas atividades econômicas básicas (unidade local única. Das empresas que operam com "mais de uma unidade local", quase dois terços delas são classificados como "empresas não diversificadas", em 2010. No que tange às "empresas diversificadas", observa-se que, quanto maior o tamanho, maior tem sido a diversificação, mas verifica-se, de modo geral, que as empresas de todos os tamanhos têm se preocupado em expandir mais por meio da "diversificação por atividade e mista" e menos por intermédio da "diversificação espacial". Considerando a diversificação por setor de atividade econômica, as empresas da construção e da indústria de transformação atingiram níveis mais elevados de diversificação em 2010. De modo geral, diversos setores mostram características distintas com relação ao tipo de diversificação e ao porte das empresas.

LIVROS DIDÁTICOS DE HISTÓRIA DA REDE SALESIANA DE ESCOLAS: prescrições e usosHISTORY TEXT-BOOKS OF THE SALESIAN SCHOOLS NETWORK: requirements and uses

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Clarícia Otto

2012-12-01

Full Text Available O livro didático é um dos dispositivos da educação escolar marcado por um emaranhado conjunto de interesses dos autores, editores, gestores institucionais, entre outros envolvidos no processo de sua fabricação. É um artefato impresso que se constitui em fonte inesgotável de pesquisa, especialmente, no que tange aos usos feitos por professores e estudantes. Assim, neste artigo, objetiva-se apresentar questões em torno da coleção de livros didáticos de História para o ensino médio da Rede Salesiana de Escolas (RSE, em Santa Catarina: contexto de fabricação, prescrições por parte da Rede e autores, sua utilização por cinco professores e 173 estudantes do ensino médio. Observou-se que o professor como mediador do processo de ensino e aprendizagem influi na forma como os estudantes se apropriam e produzem representações acerca do livro didático e do conhecimento histórico.

O PAPEL DA ALIENAÇÃO DO TRABALHO MARXIANA NA CONSTRUÇÃO DO CARÁTER SOCIAL

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Tainã Alcantara de Carvalho

2014-02-01

Full Text Available O presente artigo pretende realizar uma discussão acerca do modo de exploração do trabalho humano pelo capital enquanto fonte formadora do caráter individual e, com isto, social. Baseado no pensamento filosófico e econômico marxista, que inicia a crítica ao modo de produção capitalista calcada principalmente nas questões humanas, será demonstrado um rápido panorama da evolução dos modelos de produção a partir da Revolução Industrial até o moderno modelo de acumulação flexível, salientando nesta análise considerações a respeito da relação do ser humano com o trabalho, que permeia tanto as análises sociológicas quanto psicológicas. Partindo da ideia construída por Marx acerca da centralidade da atividade laboral ao ser humano, presente em sua teoria do materialismo histórico, o autor relata em suas obras as consequências que a alienação do trabalho, ao modo de sua época, geram à formação do indivíduo e à percepção deste sobre o mundo ao seu redor. Com base nesta ideia, pretende-se demonstrar neste artigo a continuação do papel da alienação do trabalho à constituição do ser humano no século XX, principalmente no que tange às considerações acerca dos novos valores e comportamentos adotados na modernidade.

A new genus of oak gallwasp, Cyclocynips Melika, Tang & Sinclair (Hymenoptera: Cynipidae: Cynipini), with descriptions of two new species from Taiwan.

Science.gov (United States)

Melika, George; Tang, Chang-ti; Sinclair, Frazer; Yang, Man-miao; Lohse, Konrad; Hearn, Jack; Nicholls, James A; Stone, Graham N

2013-01-01

A new genus of cynipid oak gallwasp-Cyclocynips Melika, Tang, & Sinclair (Hymenoptera: Cynipidae: Cynipini), with two new species--C. uberis and C. tumorvirgae--reared from galls on oaks of the Quercus subgenus Cyclobalanopsis is described from Taiwan. Descriptions of asexual generation adults and their diagnostic characters are presented. The likelihood of yet undiscovered sexual generations and the evolution of host-plant associations in these species are discussed.

IMPACTOS AMBIENTAIS DECORRENTES DO ATERRO SANITÁRIO DA REGIÃO METROPOLITANA DE BELÉM-PA: APLICAÇÃO DE FERRAMENTAS DE MELHORIA AMBIENTAL

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Francinaldo Oliveira Matos

2011-10-01

Full Text Available A geração indiscriminada de Resíduos Sólidos (RS causa riscos ao equilíbrio ambiental e à saúde pública ao passo que é considerado como um dos problemas ambientais mais preponderantes na atualidade. Neste trabalho foi utilizado o método de Listagem de Controle (CHECK-LIST para identificar os principais impactos ambientais presentes no aterro sanitário do município de Belém-PA. Os resultados da pesquisa indicam deficiências no processo de gestão dos RS do município, principalmente no que tange à disposição final destes no aterro do Aurá onde foi constatado um alto potencial de contaminação do solo, do ar e dos recursos hídricos. Diante da inviabilidade de realocação da área propõem-se as seguintes medidas mitigadoras: ações de monitoramento da qualidade dos recursos ambientais, operação e manutenção de uma rede de drenagem de gás e a criação de um sistema de compostagem

Yongdamsagan-tang, a traditional herbal formula, inhibits cell growth through the suppression of proliferation and inflammation in benign prostatic hyperplasia epithelial-1 cells.

Science.gov (United States)

Park, Eunsook; Lee, Mee-Young; Seo, Chang-Seob; Jeon, Woo-Young; Shin, Hyeun-Kyoo

2017-09-14

Benign prostatic hyperplasia (BPH), also called benign enlargement of the prostate, is a progressive disease that is observed in most elderly men. Yongdamsagan-tang, a traditional herbal formula, is used commonly for the treatment of inflammation-related diseases. Although the therapeutic efficacy of Yongdamsagan-tang against BPH in vivo was reported previously, its underlying mechanisms are not clearly understood. In this study, we investigated the effect of Yongdamsagan-tang water extract (YSTE) and its mechanism on the growth of human BPH epithelial BPH-1 cells. YSTE was extracted from 11 herbaceous plants and its chemical composition was analyzed by High-performance liquid chromatography (HPLC). YSTE was treated in the epithelial BPH-1 cell line and then cell lysates or supernant were used to evaluate cell viability, cell cycle, proliferation and cytokine production. HPLC revealed that Baicalin and gentiopicroside were involved as the major compounds of YSTE. YSTE treatment in BPH-1 cells repressed cell viability in a dose-dependent manner. Regarding the inhibitory mechanisms of YSTE on cell growth, YSTE inhibited cell proliferation via a decrease in endogenous cyclin D1 protein levels and arrest at the S phase during cell-cycle progression. Furthermore, YSTE treatment in BPH-1 cells suppressed prostaglandin E 2 production and cyclooxygenase-2 (COX-2) protein levels. The secretion of the proinflammatory cytokines, interleukin-8 and interleukin-6, was also reduced by YSTE treatment. YSTE in BPH-1 cells showed antiproliferative and anti-inflammatory activities via cell-cycle arrest and downregulation of COX-2 expression, respectively. Taken together, the results of the present study will enhance our understanding of the mechanisms underlying the effect of YSTE in BPH. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Effect of Xiao Chaihu Tang combined with intravenous chemotherapy on tumor markers and immune function in patients with advanced breast cancer

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Jian-Ping Zhong

2017-05-01

Full Text Available Objective: To study the effect of Xiao Chaihu Tang combined with intravenous chemotherapy on tumor markers and immune function in patients with advanced breast cancer. Methods: 76 patients with advanced breast cancer treated in our hospital between May 2012 and November 2015 were collected and divided into the combined treatment group (n=34 who accepted Xiao Chaihu Tang combined with intravenous chemotherapy and the control group (n=42 who accepted intravenous chemotherapy alone according to different treatment, and the treatment cycle was 3 months for both groups. Before treatment and 3 months after treatment, ELISA method was used to detect serum levels of broad-spectrum tumor markers and breast cancerspecific tumor markers; flow cytometer was used to detect cellular immune function index levels, and turbidimetric immunoassay was used to detect humoral immune function index levels in peripheral blood. Results: Before treatment, differences in serum tumor marker levels as well as cellular immunity and humoral immunity index levels in peripheral blood were not statistically significant between two groups of patients (P>0.05; after 3 months of treatment, broad-spectrum tumor markers carcinoembryonic antigen (CEA, carbohydrate antigen 153 (CA153 and carbohydrate antigen 125 (CA125 levels in serum of combined treatment group were lower than those of control group, and breast cancer-specific tumor markers insulin-like growth factor-1 (IGF-1, midkine (MK, soluble E-cadherin (sEC and thymidine kinase 1 (TK1 levels were lower than those of control group (P<0.05; CD3+ and CD4+ T lymphocyte levels as well as CD4+/CD8+ ratio in peripheral blood of combined treatment group were higher than those of control group while CD8+ T lymphocyte level was lower than that of control group, and immunoglobulin G (IgG, immunoglobulin A (IgA and immunoglobulin M (IgM levels in peripheral blood were higher than those of control group (P<0.05. Conclusions: Xiao Chaihu Tang

Phylogenetic relationships of Hemiuridae (Digenea: Hemiuroidea) with new morphometric and molecular data of Aphanurus mugilis Tang, 1981 (Aphanurinae) from mullet fish of Vietnam.

Science.gov (United States)

Atopkin, D M; Besprozvannykh, V V; Yu Beloded, A; Ngo, H D; Ha, N V; Tang, N V

2017-12-01

Adult Aphanurus mugilis Tang, 1981 worms were detected in the intestine of Moolgarda engeli in the shallow waters off Cat Ba Island, Vietnam. Tang (1981) first described this species in Mugil cephalus off China. The worms in Vietnamese mullet were identical to Chinese specimens in a number of morphometric characteristics, with the exception of body and ovary size. In the present study, morphological characteristics, and the first molecular data for A. mugilis are provided. Additionally, molecular phylogenetic analysis of the family Hemiuridae was performed. The results of our molecular phylogenetic study indicate that the presence or absence of an ecsoma was not associated with molecular data for hemiurid subfamilies differentiation. The basal position of Bunocotylinae on the molecular-based phylogenetic tree indicated a primordial nature of ecsoma of hemiurid trematodes. Considerable molecular differentiation of Bunocotylinae from other hemiurids indicated the possibility of the recognition of the family Bunocotylidae Dollfus, 1950. Assuming that Machidatrema chilostoma is considered within the Bunocotylinae, the paraphyly of the Lecithasterinae was supported. Copyright © 2017 Elsevier B.V. All rights reserved.

Changes of Some Indices of Low Flow affected by Climate Change in the Tang Panj Sezar Basin

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M. Mozayyan

2016-10-01

Full Text Available Introduction: Due to the effects of climate change on water resources and hydrology, Changes in low flow as an important part of the water cycle, is of interest to researchers, water managers and users in various fields. Changes in characteristics of low flows affected by climate change may have important effects on various aspects of socioeconomic , environmental, water resources and governmental planning. There are several indices to assess the low flows. The used low flow indices in this research for assessing climate change impacts, is include the extracted indices from flow duration curve (Q70, Q90 and Q95, due to the importance of these indices in understanding and assessing the status of river flow in dry seasons that was investigated in Tang Panj Sezar basin in the west of Iran. Materials and methods: In this paper, the Tang Panj Sezar basin with an area of 9410 km2 was divided into 6 smaller sub catchments and the changes of low flow indices were studied in each of the sub catchments. In order to consider the effects of climate change on low flow, scenarios of temperature and precipitation using 10 atmospheric general circulation models (to investigate the uncertainty of GCMs for both the baseline (1971-2000 and future (2011-2040 under A2 emission scenario was prepared. These scenarios, due to large spatial scale need to downscaling. Therefore, LARS-WG stochastic weather generator model was used. In order to consider the effects of climate change on low flows in the future, a hydrologic model is required to simulate daily flow for 2011-2040. The IHACRES rainfall-runoff model was used for this purpose . After simulation of daily flow using IHACRES, with two time series of daily flow for the observation and future period in each of the sub catchment, the low flow indices were compared. Results Discussion: According to results, across the whole year, the monthly temperature in the future period has increased while rainfall scenarios show

The influence of intestine-based treatment using Xuan Bai Cheng Qi Tang on the concentration of trace elements in the main organs of COPD rats

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Jiamin Yang

2017-01-01

Conclusion: This study showed that “treating from the intestine” using Xuan Bai Cheng Qi Tang and its modified formulae can regulate the concentration of trace elements in the main organs of COPD rats. This may be one of the mechanisms for intestine-based treatment for COPD.

Total Glucosides of Danggui Buxue Tang Attenuate BLM-Induced Pulmonary Fibrosis via Regulating Oxidative Stress by Inhibiting NOX4

Science.gov (United States)

Zhao, Ping; Zhou, Wen-Cheng; Li, De-Lin; Mo, Xiao-Ting; Xu, Liang; Li, Liu-Cheng; Cui, Wen-Hui; Gao, Jian

2015-01-01

Pulmonary fibrosis (PF) is a serious chronic lung disease with unknown pathogenesis. Researches have confirmed that oxidative stress which is regulated by NADPH oxidase-4 (NOX4), a main source of reactive oxygen species (ROS), is an important molecular mechanism underlying PF. Previous studies showed that total glucosides of Danggui Buxue Tang (DBTG), an extract from a classical traditional Chinese herbal formula, Danggui Buxue Tang (DBT), attenuated bleomycin-induced PF in rats. However, the mechanisms of DBTG are still not clear. We hypothesize that DBTG attenuates PF through regulating the level of oxidative stress by inhibiting NOX4. And we found that fibrosis indexes hydroxyproline (HYP) and type I collagen (Col-I) were lower in DBTG groups compared with the model group. In addition, the expression of transforming growth factor-β1 (TGF-β1) and expression of alpha smooth muscle actin (α-SMA) were also much more decreased than the model group. For oxidative stress indicators, DBTG blunted the decrease of superoxide dismutase (SOD) activity, total antioxidant capacity (T-AOC), and the increase in malondialdehyde (MDA), 8-iso-prostaglandin in lung homogenates. Treatment with DBTG restrained the expression of NOX4 compared to the model group. Present study confirms that DBTG inhibits BLM-induced PF by modulating the level of oxidative stress via suppressing NOX4. PMID:26347805

Preliminary geologic map of the Big Costilla Peak area, Taos County, New Mexico, and Costilla County, Colorado

Science.gov (United States)

Fridrich, Christopher J.; Shroba, Ralph R.; Hudson, Adam M.

2012-01-01

This map covers the Big Costilla Peak, New Mex.&nash;Colo. quadrangle and adjacent parts of three other 7.5 minute quadrangles: Amalia, New Mex.–Colo., Latir Peak, New Mex., and Comanche Point, New Mex. The study area is in the southwesternmost part of that segment of the Sangre de Cristo Mountains known as the Culebra Range; the Taos Range segment lies to the southwest of Costilla Creek and its tributary, Comanche Creek. The map area extends over all but the northernmost part of the Big Costilla horst, a late Cenozoic uplift of Proterozoic (1.7-Ga and less than 1.4-Ga) rocks that is largely surrounded by down-faulted middle to late Cenozoic (about 40 Ma to about 1 Ma) rocks exposed at significantly lower elevations. This horst is bounded on the northwest side by the San Pedro horst and Culebra graben, on the northeast and east sides by the Devils Park graben, and on the southwest side by the (about 30 Ma to about 25 Ma) Latir volcanic field. The area of this volcanic field, at the north end of the Taos Range, has undergone significantly greater extension than the area to the north of Costilla Creek. The horsts and grabens discussed above are all peripheral structures on the eastern flank of the San Luis basin, which is the axial part of the (about 26 Ma to present) Rio Grande rift at the latitude of the map. The Raton Basin lies to the east of the Culebra segment of the Sangre de Cristo Mountains. This foreland basin formed during, and is related to, the original uplift of the Sangre de Cristo Mountains which was driven by tectonic contraction of the Laramide (about 70 Ma to about 40 Ma) orogeny. Renewed uplift and structural modification of these mountains has occurred during formation of the Rio Grande rift. Surficial deposits in the study area include alluvial, mass-movement, and glacial deposits of middle Pleistocene to Holocene age.

Genoprotective effect of the Chinese herbal decoction xiao jian zhong tang.

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Szeto, Yim-Tong; Cheng, Ngok-Fung; Pak, Sok-Cheon; Kalle, Wouter

2013-03-01

The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P < 0.05) was found for individual herb extracts, but XJZT showed protection of human lymphocytic DNA upon oxidative stress (P < 0.05). The in vitro DNA protection effect of XJZT was conferred by the synergistic effect of the herbs, while the individual herbs had no such effect.

Conundrums in the legal protection of migrant workers' health rights and relative resolutions: implications from the case of Tseng Hei-tao.

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Liu, Kai

2013-08-01

The deteriorating situation of migrant workers' health rights protection was once again highlighted in the case of Tseng Hei-tao. This case explicitly and implicitly showed that four conundrums--the Employment Restriction Conundrum, the Occupational Safety and Health (OSH) Legal Conundrum, the Morality Conundrum and the Identity Conundrum--are barriers to migrant workers' right protection. The health rights of migrant workers could be safeguarded by abolishing the outdated household registration system designed in the planned economy era, improving the rule of law, and strengthening administrative supervisions. This would fundamentally remove these barriers and thus contribute to migrant workers' health rights protection.

Apontamentos epistemológicos a propósito da crise brasileira

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Cremilda Celeste de Araújo Medina

2018-04-01

Full Text Available Tendo em vista a compreensão do Jornalismo entre as narrativas da contemporaneidade, imerso em um conjunto de limitações epistemológicas - paradigmas vencidos, observação carente de experiências presenciais e análises precipitadas ou provenientes de reducionismos mentais -, este artigo busca, a partir de uma leitura integral dos periódicos Folha de S. Paulo e Estado de S. Paulo, no primeiro semestre de 2017, encontrar a manifestação de uma voz autoral que assine a voz coletiva no que tange a crise brasileira. Percebe-se, nesta leitura cultural, que é no Jornalismo de opinião que a imaginação criadora perante o caos alimenta quebras da razão analítica aprisionada pela esfera conceitual dada. O toque ensaístico se manifesta contrário, reticente, pluralista perante as afirmações/certezas estabelecidas. Conclui-se com uma proposta: o estímulo à reportagem-ensaio. Nela, o repórter que ousa a observação-experiência ensaia a compreensão sutil inspirada na responsabilidade ética, na qualificação técnica e na criatividade estética, permitindo romper com os reducionismos vigentes.

Primeiras aproximações de uma análise do financiamento da política nacional de esporte e lazer no Governo Lula

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Pedro Athayde

2015-03-01

Full Text Available Este artigo realiza uma análise introdutória sobre o gasto público referente às políticas de esporte e lazer no Governo Lula. Os dados coletados apresentaram uma distribuição instável entre os programas, o que impede o estabelecimento de um padrão de financiamento para o esporte e lazer durante o período analisado (2003-2010, bem como de afirmar a existência de programas e/ou frações de classes hegemônicas no que tange aos gastos públicos do setor. Todavia, algumas particularidades indicam a razoabilidade do pressuposto sobre a priorização do esporte de alto rendimento dentro da alocação dos recursos públicos destinados ao financiamento da Política Nacional de Esporte e Lazer (PNEL do Governo Lula.

A Reestruturação da cidade de Salvador: Conflitos e interesses na lógica da centralidade urbana

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Jânio Santos

2010-07-01

Full Text Available A partir da metade do século XX, ocorreram transformações políticas e econômicas que influenciaram a urbanização, consequentemente, a produção do espaço urbano em Salvador/BA. Essas mudanças provocaram alterações em sua estrutura urbana, sendo as mais importantes: a constituição de novas relações tempo-espaço, a implantação de hodiernos equipamentos e a redefinição na centralidade urbana, marcando o início do processo de reestruturação urbana e da cidade. Como consequência, atualmente, Salvador apresenta uma estrutura urbana poli(multi nucleada. Por um lado, esse fenômeno revela a formação de novas áreas centrais, ou seja, “eclodiu” uma multiplicidade de centros e subcentros na cidade; por outro, percebe-se que esses espaços são bastante diferenciados entre si, mormente, no que tange às características sociais e econômicas, por isso também verificamos sua face poli. A constituição dessa nova lógica na centralidade soteropolitana revela nuances diferenciadas nos conflitos e interesses na cidade, que entendemos interferir no processo de produção e reprodução do espaço urbano, sobretudo no que tange à produção de espaços destinados ao consumo. Abstract THE RESTRUCTURATION OF THE CITY OF SALVADOR: CONFLICTS AND INTERESTS IN THE URBAN CENTRALITY LOGIC After 1950 some economic and political transformations occurred, influencing in the urbanization process of the city of Salvador/BA. These changes provoked some important changes in the urban structure, such as the redefinition of the time-space relationship and the introduction of new equipments, marking the start of urban and city restructuration. The process was produced by the State, among with other agents, and its consequences demonstrate the formation of a new characteristic of the urban structure, understood as the multi(polycentralité. The current centers are differentiated by the amount and by the interests of the social groups. The olds

O Papel da ONU e do Banco Mundial na Consolidação do Campo Internacional de Desenvolvimento

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Fernanda Cimini Salles

2015-12-01

Full Text Available ResumoO artigo tem por objetivo resgatar o processo histórico de construção do modus operandi das práticas de desenvolvimento, destacando o papel das organizações internacionais nesse processo e como elas mobilizavam seus recursos tangíveis e intangíveis para a conformação de uma agenda legítima de intervenção social. A análise terá como foco as dinâmicas políticas que sucederam a Comissão Pearson, conferência internacional realizada em 1969, que teve como objetivo repensar e propor diretrizes internacionais para o desenvolvimento. O ponto crítico deste momento será o reconhecimento, por parte do Banco Mundial e da ONU, de que a cooperação internacional para o desenvolvimento mobilizava diferentes projetos de coordenação societária que tinham como pano de fundo o problema da desigualdade internacional. A partir da análise dos documentos e discursos da época, é possível perceber que, embora a ONU e o Banco Mundial compartilhassem a percepção de que a ajuda internacional ainda teria um papel a cumprir, esses organismos ofereciam agendas distintas para solucionar o problema do subdesenvolvimento. Com isso, buscar-se-á identificar o projeto que sai vitorioso desse embate e nos fornece elementos para a compreensão da sobrevivência e ampliação da agenda de desenvolvimento no pós-Guerra Fria.

O acidente da plataforma de petróleo P-36 revisitado 15 anos depois: da gestão de situações incidentais e acidentais aos fatores organizacionais

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Marcelo Gonçalves Figueiredo

2018-03-01

Full Text Available Resumo: O acidente com a plataforma P-36 na Bacia de Campos, Rio de Janeiro, Brasil, se configura como um dos grandes desastres internacionais da indústria do petróleo. Nosso objetivo na reflexão aqui empreendida é: (a verificar, com base em um caso específico, a questão do papel que exerce a dimensão humana na confiabilidade de sistemas de elevada complexidade - com foco na gestão de situações incidentais e acidentais -, capazes de acarretar acidentes de grande magnitude. E, ao nos debruçarmos sobre tal intento, somos remetidos à necessidade de (b dar visibilidade à interveniência de alguns dos fatores organizacionais como elementos que podem contribuir para agravar o grau de risco da atividade em plataformas offshore, conduzindo a análise para além das chamadas causas imediatas. No que tange aos métodos de investigação, tomamos por base, principalmente, a pesquisa documental (com destaque para os relatórios da Petrobras, ANP/DPC e CREA-RJ e as interlocuções que mantivemos com três profissionais que atuaram na P-36. Os resultados indicam que a gestão das situações incidentais e acidentais, na qual se circunscrevem as tomadas de decisão em contextos emergenciais, deve se valer da contribuição que os trabalhadores podem agregar no sentido de apontar e discutir com os gestores certas lacunas do processo, por intermédio do compartilhamento e da flexibilização de decisões e da análise coletiva das situações de risco. Indicam também que determinados fatores organizacionais contribuíram para a ocorrência do sinistro, corroborando estudos nacionais e internacionais acerca de grandes acidentes, que apontam para a necessidade de mudança no enfoque adotado pela gerência das empresas do setor petrolífero.

Immune checkpoint blockade therapy: The 2014 Tang prize in biopharmaceutical science

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Ya-Shan Chen

2015-02-01

Full Text Available The first Tang Prize for Biopharmaceutical Science has been awarded to Prof. James P. Allison and Prof. Tasuku Honjo for their contributions leading to an entirely new way to treat cancer by blocking the molecules cytotoxic T lymphocyte-associated antigen 4 (CTLA-4 and programmed cell death protein 1 (PD-1 that turn off immune response. The treatment, called "immune checkpoint blockade therapy," has opened a new therapeutic era. Here the discoveries of the immune checkpoints and how they contribute to the maintenance of self-tolerance, as well as how to protect tissues from the excess immune responses causing damage are reviewed. The efforts made by Prof. Allison and Prof. Honjo for developing the most promising approaches to activate therapeutic antitumor immunity are also summarized. Since these certain immune checkpoint pathways appear to be one of the major mechanisms resulting in immune escape of tumors, the presence of anti-CTLA-4 and/or anti-PD-1 should contribute to removal of the inhibition signals for T cell activation. Subsequently, it will enhance specific T cell activation and, therefore, strengthen antitumor immunity.

A cultura organizacional do restaurante chalé da praça XV em Porto Alegre: espaços e tempos sendo revelados

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Letícia Dias Fantinel

2010-02-01

Full Text Available Este estudo busca desvendar aspectos da cultura organizacional de um restaurante, ponto turístico da cidade de Porto Alegre, compreendendo sua dimensão simbólica por meio das representações sociais que circulam em seu ambiente, notadamente no que tange às categorias espaço e tempo. Em virtude da complexidade do tema, foram utilizados conceitos e quadros de referência teóricos da antropologia e de outras ciências humanas. O Chalé da Praça XV é um patrimônio que se localiza no centro histórico da cidade, espaço antigo, valorizado no passado pela população e hoje considerado uma vítima da degradação urbana. O método etnográfico foi utilizado na identificação das representações que circulam nesse espaço. O trabalho de campo etnográfico foi conduzido no restaurante entre fevereiro e maio de 2008. Identificaram-se as representações de tempo e espaço elaboradas por clientes e funcionários do restaurante, e desvendaram-se as homogeneidades e as heterogeneidades de sua cultura organizacional. As categorias de análise estabelecidas evidenciam as heterogeneidades presentes em seu espaço como lugar antropológico. Por fim, apresentam-se algumas alternativas para que se pense a gestão do estabelecimento, considerando, entre outros aspectos, seu potencial turístico insuficientemente explorado.

PESQUISA DE SATISFAÇÃO RELACIONADA À QUALIDADE DA CENTRAL DE ATENDIMENTO SOB A ÓTICA DO CLIENTE INTERNO

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Deise Taiana Ávila Dias

2013-12-01

Full Text Available Este estudo teve como objetivo avaliar a qualidade dos serviços prestados pela central de atendimento sob a ótica do cliente interno. Para abordar este objetivo, foram concretizados os objetivos específicos que consistiam em: conceituar qualidade de serviços; elencar critérios da qualidade de serviços; realizar uma pesquisa de satisfação dos clientes internos. Além disso, foi um estudo de caso descritivo com abordagem quantitativa, levando-se em conta as cinco dimensões da qualidade dos serviços, utilizando-se do questionário estruturado, como instrumento proposto pelos autores Parasuraman, Zeithaml e Berry (2011. Assim, conta com perguntas fechadas de múltipla escolhas e proporciona escalas tipo Likert, identificando-se as percepções, expectativas, opiniões e críticas em relação ao serviço prestado pela central de atendimento. Portanto, a análise dos dados possibilita identificar o que a empresa está atendendo satisfatoriamente; nesse sentido, a pesquisa incorpora as cinco dimensões da qualidade de serviços: confiabilidade, responsividade, segurança, empatia e tangíveis, e seus resultados são aceitáveis para a empresa.

Experiência antecipada: a influência da imagem da marca na relação dos usuários com aplicativo móvel Spotify

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Maurício Elias Dick

2016-08-01

Full Text Available O processo de construção da experiência do usuário com determinado produto ou serviço é composto por diversos fatores. Alguns deles incluem emoções, preferências e percepções que são capazes de gerar uma categoria de experiência que ocorre antes mesmo do uso. A chamada experiência antecipada é desencadeada por diversos agentes, podendo-se destacar, dentre eles, as ações de branding, publicidade, demonstrações e até mesmo a opinião de outros usuários. Este artigo, portanto, objetivou evidenciar em que medida a experiência antecipada com a imagem de uma marca pode influenciar o usuário durante a experiência de uso com os seus produtos ou serviços. Para isso, realizou-se uma análise do Spotify - um serviço de música digital em streaming. O estudo teve caráter quali-quantitativo e efetivou-se a partir de um processo orientado pela taxonomia de Hassenzahl, Schöbel e Trautmann [6] que apresenta uma lista de qualidades hedônicas, pragmáticas e de apelo geral. Concluiu-se que os canais de comunicação são capazes de gerar expectativas concretas da experiência de uso – principalmente no que tange os aspectos hedônicos e de apelo geral. Além disso, considerou-se o posicionamento da marca Spotify coerente, uma vez que as expectativas, de um modo geral, corresponderam às impressões obtidas pelos usuários entrevistados.

Hierarquização da eficiência de remoção de cianotoxinas por meio de adsorção em carvão ativado granular

OpenAIRE

Maria Natália Costa e Silva; Rui de Oliveira; Beatriz Susana Ovruski Ceballos; Alaine Brito Guerra; Sérgio Francisco de Aquino; Marcelo Libânio

2017-01-01

RESUMO O trabalho objetivou avaliar a remoção concomitante de duas cianotoxinas - microcistina-LR e saxitoxina-STX - por meio da adsorção em carvão ativado granular. Em primeira etapa, três carvões de granulometrias distintas, dois de coco de dendê e um mineral, foram avaliados na adsorção de microcistina-LR em água destilada e tratada com concentrações de 3,9 a 9,4 ug.L-1. O carvão de coco de dendê de menor granulometria apresentou desempenho mais uniforme, tanto no que tange à remoção (%) d...

Psicologia, diretrizes curriculares e processos educativos na Amazônia: um estudo da formação de psicólogos

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Tânia Suely Azevedo Brasileiro

Full Text Available Este estudo objetiva analisar a formação de psicólogos frente às Diretrizes Curriculares Nacionais para os Cursos de Psicologia no que tange aos processos educativos. Realizamos revisão da literatura pertinente ao tema, pesquisa documental e empírica com alunos, professores e coordenador de curso, utilizando questionário, entrevistas e adotando a estratégia de triangulação a partir das categorias: perfil sociocultural; nível de conhecimento acerca das mudanças oriundas das Diretrizes para o curso de Psicologia; percepção na qualidade da prática docente; nível de satisfação com relação à própria formação universitária, tomando como referência os conhecimentos, habilidades e competências adquiridas. Apresenta contribuições para a compreensão da formação de psicólogos no campo da educação na Amazônia no Ensino Superior, centrada na construção de um profissional de pensamento e prática críticos, capaz de analisar as transformações nos vários contextos educacionais e escolares, utilizando referenciais que permitam a compreensão do fenômeno educativo na sua complexidade.

Nova gestão pública na Noruega: o papel do contexto nacional na mediação da reforma educacional

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Jorunn Møller

2015-09-01

Full Text Available RESUMO: Desde o final dos anos 1980, o sistema educacional norueguês passou por grandes reformas amplamente influenciadas pelas novas ideias gerencialistas. As estratégias para renovar o setor público foram promovidas com a nova gestão pública (NGP. Este artigo investiga a forma pela qual as ideias ligadas às reformas da NGP foram introduzidas e interpretadas no setor educacional norueguês. Com base em nossos estudos de documentos de políticas públicas selecionados, de um período que compreende as últimas duas décadas, identificamos três áreas de luta discursiva. A primeira está vinculada a ideologias e à história nacional de escolarização; a segunda está relacionada a assuntos debatidos no que tange ao profissionalismo docente e, a terceira, está associada às estratégias de modernização e melhoria da educação. Um argumento central é que as reformas da NGP mudaram de direção e foram aceleradas quando a Noruega foi listada entre os países com "baixo desempenho" de acordo com o Pisa e outros testes internacionais. A liderança e a responsabilização (accountability se tornaram os temas dominantes no campo da educação norueguesa.

Cuidados com cateter central de inserção periférica no neonato: revisão integrativa da literatura

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Derdried Athanasio Johann

2012-12-01

Full Text Available O cateter central de inserção periférica é tecnologia comum empregada na terapia intravenosa de neonatos. Trata-se de revisão integrativa, cujo objetivo foi investigar e analisar as evidências disponíveis na literatura acerca da temática. As bases de dados pesquisadas foram Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS e Biblioteca Nacional de Medicina dos Estados Unidos (PubMed. Resultados apontam lacunas no que tange à população neonatal; conhecimento insuficiente dos profissionais quanto indicações (n=1; e variados temas sobre uso de anticoagulantes (n=6, comparação com outros cateteres (n=4, diagnóstico por imagem (n=2, dor (n=2, infecção relacionada a cateter e sua prevenção (n=7, entre outros fatores. Conclui-se que há necessidade de atualização profissional, evidências científicas de fácil acesso e publicações nacionais.

Optimization of high pressure machine decocting process for Dachengqi Tang using HPLC fingerprints combined with the Box–Behnken experimental design

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Rui-Fang Xie

2015-04-01

Full Text Available Using Dachengqi Tang (DCQT as a model, high performance liquid chromatography (HPLC fingerprints were applied to optimize machine extracting process with the Box–Behnken experimental design. HPLC fingerprints were carried out to investigate the chemical ingredients of DCQT; synthetic weighing method based on analytic hierarchy process (AHP and criteria importance through intercriteria correlation (CRITIC was performed to calculate synthetic scores of fingerprints; using the mark ingredients contents and synthetic scores as indicators, the Box–Behnken design was carried out to optimize the process parameters of machine decocting process under high pressure for DCQT. Results of optimal process showed that the herb materials were soaked for 45 min and extracted with 9 folds volume of water in the decocting machine under the temperature of 140 °C till the pressure arrived at 0.25 MPa; then hot decoction was excreted to soak Dahuang and Mangxiao for 5 min. Finally, obtained solutions were mixed, filtrated and packed. It concluded that HPLC fingerprints combined with the Box–Behnken experimental design could be used to optimize extracting process of traditional Chinese medicine (TCM. Keywords: Dachengqi Tang, HPLC fingerprints, Box–Behnken design, Synthetic weighing method

The study is believed to be used to treat illnesses Yau ceremony of Phutai. Natal village , Tambon Tao Ngoi, Tao Ngoi District, Sakon Nakhon Province

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Boonchom Srisa-ard

2016-12-01

Full Text Available This research aimed to 1 study the beliefs and the cause of the ailments of the ceremony to Yau. Which is from Thailand, Village Natal district, Tao Ngoi District, Sakon Nakhon 2 to study the composition of the ceremony Yao and 3 to study the Yau ceremony. The method resources from data collection divided into two parts, there were 1 documentation research articles, theses, books, textbooks and information from the Internet, and 2 the interview with the people who knew the four ceremonies of You. The study found the phenomenon as follows: 1 Belief in the Yau ceremony, that Yau is believed to cure illness, disease caused by an act of the devil. The treatment with modern medicine can not be cured. Parents or family elders had prior therapy with Yau. The disease which is believed to occur in this manner must be gone because of Yao. Some of which can actually be cured, mean while some extended for several more years. The treatment facilities for patients is that Yao can be come home. And pitched immediate treatment faster than the health center or hospital where the procedure was hospitalized several timeconsuming steps. 2 The components of Yau ceremony, are Yau illnesses, Yau is patient, the Yao spit, and music instruments. 3 The ceremony of Yau has five phases: preparation before starting the ceremony. Next, the invitation to the major deities or spirits. then Yao toss the cause of the illness. the reassure patients to leave the various deities and spirits. leave the body return to and live in their residence.

Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

OpenAIRE

Chan, Yuan-Yu; Chen, Yi-Hung; Yang, Szu-Nian; Lo, Wan-Yu; Lin, Jaung-Geng

2015-01-01

Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI) scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed ...

COMPORTAMENTO DO CONSUMIDOR DE VINHOS DA REGIÃO DAS MISSÕES: UMA INVESTIGAÇÃO SOBRE OS FATORES INFLUENCIADORES

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Lara Denise Basso

2016-10-01

Full Text Available Este estudo analisa o comportamento do consumidor de vinhos da Região das Missões - RS, a partir da investigação de quais fatores mais influenciam os hábitos de consumo, entre os fatores psicológicos, sociais, culturais e pessoais. No que diz respeito à base teórica, essa foi construída pautada em conceitos de comportamento do consumidor, bem como nos quatro fatores que o influenciam. Além disso, apresenta-se uma breve contextualização do vinho no RS. Quanto aos procedimentos metodológicos, esta pesquisa, caracterizada como descritiva de abordagem quantitativa ,investigou 158 pessoas em três municípios: Cerro Largo, São Luiz Gonzaga e Santo Ângelo, pro meio de uma pesquisa survey. Os questionários foram aplicados presencialmente junto aos respondentes. No que tange aos resultados, percebeu-se que os fatores que mais impactam o comportamento do consumidor de vinhos da região estudada são os fatores sociais, recebendo destaque a influência da família no comportamento de consumo. Além disso, entre os fatores motivadores do consumo de vinho, segundo a percepção dos respondentes, está o fato de a bebida fazer bem para a saúde, além de provocar sensação de bem-estar. Quanto às ocasiões de consumo, a maior parte dos respondentes gosta de consumir vinho em sua própria residência. No que diz respeito aos critérios utilizados para a escolha do vinho, a maioria costuma dar importância à cor da bebida e, quanto aos locais de aquisição, mais da metade dos respondentes costuma adquirir vinhos em viagens. Palavras-Chave: Comportamento do Consumidor. Vinhos. Fatores Influenciadores.

Avaliação da capacidade probiótica de uma linhagem de Ruminococcus gnavus da microbiota fecal de seres humanos contra Clostridium perfringens

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Flávio Henrique Ferreira Barbosa

2011-03-01

Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE MicrosoftInternetExplorer4 Probióticos são microrganismos utilizados com o propósito de beneficiar a saúde do hospedeiro, seja na prevenção ou tratamento de doenças. Este trabalho teve como objetivo avaliar uma cultura de Ruminococcus gnavus quanto ao seu efeito probiótico frente a um alvo patogênico in vivo por meio de avaliação histopatológica e perfil de hidrofobicidade da parede celular. A linhagem de R. gnavus foi isolada da microbiota fecal dominante de um adulto sadio. Uma amostra padrão de Clostridium perfringens foi utilizada como patógeno para o desafio por via oral de camundongos previamente monoassociados com R. gnavus. Camundongos suíços NIH isentos de germes foram usados como modelo animal. Nos resultados dos testes de adesão da superfície celular do microrganismo estudado, ficou constatado que a espécie R. gnavus possui uma parede celular mais hidrofóbica e ácida, sinalizando boa probabilidade de adesão ao epitélio intestinal. A análise histológica demonstrou que a monoassociação com R. gnavus não promoveu nenhuma alteração morfológica dos órgãos analisados (intestinos, baço e fígado, e apresentou efeito protetor, constatado no ceco e no fígado de camundongos gnotobióticos. Em suma, os resultados reforçam que R. gnavus possui características protetoras desejáveis no que tange a elaboração de futuros probióticos.

Investigation of Kelvin wave periods during Hai-Tang typhoon using Empirical Mode Decomposition

Science.gov (United States)

Kishore, P.; Jayalakshmi, J.; Lin, Pay-Liam; Velicogna, Isabella; Sutterley, Tyler C.; Ciracì, Enrico; Mohajerani, Yara; Kumar, S. Balaji

2017-11-01

Equatorial Kelvin waves (KWs) are fundamental components of the tropical climate system. In this study, we investigate Kelvin waves (KWs) during the Hai-Tang typhoon of 2005 using Empirical Mode Decomposition (EMD) of regional precipitation, zonal and meridional winds. For the analysis, we use daily precipitation datasets from the Global Precipitation Climatology Project (GPCP) and wind datasets from the European Centre for Medium-Range Weather Forecasts (ECMWF) Interim Re-analysis (ERA-Interim). As an additional measurement, we use in-situ precipitation datasets from rain-gauges over the Taiwan region. The maximum accumulated precipitation was approximately 2400 mm during the period July 17-21, 2005 over the southwestern region of Taiwan. The spectral analysis using the wind speed at 950 hPa found in the 2nd, 3rd, and 4th intrinsic mode functions (IMFs) reveals prevailing Kelvin wave periods of ∼3 days, ∼4-6 days, and ∼6-10 days, respectively. From our analysis of precipitation datasets, we found the Kelvin waves oscillated with periods between ∼8 and 20 days.

Uma análise exploratória dos programas de controle da tuberculose da bahia e goiás à luz da teoria dos custos de transação An exploratory analysis of the tuberculosis control program of the states of bahia and goiás from a transaction cost theory perspective

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Sebastião Loureiro

2013-03-01

Full Text Available Em caráter exploratório, o objetivo deste artigo é analisar o Programa de Controle da Tuberculose (PCTs dos Estados da Bahia e Goiás e respectivas capitais, Salvador e Goiânia, a partir da Teoria dos Custos de Transação. Para tanto, foi realizado um estudo de caso nos PCTs citados, utilizando-se, junto aos seus gestores, do método de entrevistas aprofundadas semidiretivas. Os resultados sugerem: (a baixa especificidade em ativos humanos; (b baixo grau de incerteza - relacionada à flutuação da demanda e à introdução de novas tecnologias (medicamentos; (c aspectos relacionados à racionalidade limitada (informação incompleta são pouco relevantes - no que tange à redação do contrato (Programa Nacional de Controle da Tuberculose - PNCT e ao Sistema de Informação de Agravos de Notificação (SINAN; (d e alta probabilidade de ocorrência de comportamento de tipo oportunista (risco moral - devido ao não monitoramento das ações, à ausência de punições em caso de descumprimento das ações pactuadas no PNCT e ao regime de incentivos vigente.From a Transaction Cost Theory perspective, the paper aims to discuss the Programa de Controle da Tuberculose (PCT - Tuberculosis Control Program of the States of Bahia and Goiás and their Capital Cities, Salvador and Goiânia. A case study was carried out applying a research questionnaire to the PCT managers. The results indicate: (a low specificity in human assets; (b low uncertainty - related to fluctuations in demand and to the introduction of new technologies (drugs; (c aspects related to bounded rationality (incomplete information are not important - related to the contract (PNCT and the SINAN; (d and high probability of opportunism (moral hazard, due to lack of monitoring of the actions, lack of punishment in case of default of actions agreed upon in the PNCT, and the current incentive regime.

O ensino da escrita e o desenvolvimento das pessoas com deficiência intelectual

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Solange Marques Rossato

2013-12-01

Full Text Available O presente artigo propõe uma reflexão teórica acerca do desenvolvimento das crianças com deficiência intelectual no que tange à importância e à necessidade de aprender a linguagem escrita, do ponto de vista da Teoria Histórico-Cultural. Para essa abordagem, o curso de desenvolvimento de uma criança, considerada deficiente ou não, ocorrerá conforme as condições culturais e sociais em que ela estiver inserida. Assim, no tocante à criança com deficiência intelectual, a sua condição cultural, em relação dinâmica com os entraves colocados por sua condição especial, será a fonte de seu desenvolvimento. Se o desenvolvimento das funções psicológicas superiores se realiza mediante o uso de ferramentas e se as pessoas com deficiência intelectual apresentam inaptidão para o uso dessas ferramentas, será necessário criar meios auxiliares para elas poderem aprender a utilizá-las, como meio de formar e desenvolver as suas funções psíquicas. Nesse processo, o ensino e a apropriação da linguagem escrita são vias fundamentais de acesso ao mundo cultural, numa mais ampla significação da comunicação, do mundo e de si mesmo. Em suma, os educadores compreenderem a relevância do ensino intencional da linguagem escrita e do processo histórico que a constitui representa uma contribuição fundamental para o processo de humanização das crianças com deficiência.

Desenvolvimento da relação de cooperação mediada por computador em ambiente de educação a distância

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Ivan Ferrer Maia

2006-12-01

Full Text Available O artigo contempla parte dos resultados de uma pesquisa-ação desenvolvida junto aos agentes de saúde dos bairros São Marcos e Santa Mônica, em Campinas-SP. Trata-se de pesquisa longitudinal, com duração de um ano e meio, envolvendo três fases: presencial, semipresencial e a distância. Aqui tratamos apenas das atividades ocorridas na fase presencial, nas quais os agentes começaram a aprender a utilizar o computador, e do TelEduc. Para tanto, optamos por uma observação qualitativa, já que o objetivo principal foi aferir os estágios de desenvolvimento de Piaget com a capacidade dos agentes em dominar as entidades tangíveis e intangíveis da informática (compreendem-se as entidades tangíveis como os elementos de hardware; e as entidades intangíveis, como os de software. Essa relação foi possível quando eles, de maneira presencial, começaram a interagir com os elementos básicos do computador e com o TelEduc. Após superarem a anomia e terem dominado as ferramentas que favoreceram posturas heterônomas, os agentes manipularam recursos que permitiram o começo de uma relação de cooperação.

Origin of stratiform sediment-hosted manganese carbonate ore deposits: Examples from Molango, Mexico, and TaoJiang, China

Science.gov (United States)

Okita, P.M.; Shanks, Wayne C.

1992-01-01

Carbonate and sulfide minerals from the Molango, Mexico, and TaoJiang, China, Mn deposits display similar and distinctive ??34S and ??13C patterns in intervals of manganese carbonate mineralization. ??13C-values for Mn-bearing carbonate range from -17.8 to +0.5??? (PDB), with the most negative values occurring in high-grade ore zones that are composed predominantly of rhodochrosite. In contrast, calcite from below, within and above Mn-carbonate zones at Molango has ??13C???0??? (PDB). Markedly negative ??13C data indicate that a large proportion of the carbon in Mn-carbonates was derived from organic matter oxidation. Diagenetic reactions using MnO2 and SO2-4 to oxidize sedimentary organic matter were the principle causes of such 12C enrichment. Pyrite content and sulfide ?? 34S-values also show distinctive variations. In unmineralized rocks, very negative ??34S-values (avg. < -21??? CDT) and abundant pyrite content suggest that pyrite formed from diagenetic, bacteriogenic sulfate reduction. In contrast, Mn-bearing horizons typically contain only trace amounts of pyrite (e.g., <0.5 wt% S with ??34S-values 34S-enriched, in some cases to nearly the value for contemporaneous seawater. 34S-enriched pyrite from the Mn-carbonate intervals indicates sulfide precipitation in an environment that underwent extensive SO2-4 reduction, and was largely a closed system with regard to exchange of sulfate and dissolved sulfide with normal seawater. The occasional occurrence of 34S-depleted pyrite within Mn-carbonate zones dominated by 34S-enriched pyrite is evidence that closed-system conditions were intermittent and limited to local pore waters and did not involve entire sedimentary basins. Mn-carbonate precipitation may have occluded porosity in the surficial sediments, thus establishing an effective barrier to SO2-4 exchange with overlying seawater. Similar isotopic and mineralogic characteristics from both the Molango and TaoJiang deposits, widely separated in geologic time and

The Trading Company of the Don Cossacks and MLiTAO in 1917: Breaking Traditional Foundations or Adapting to New Conditions. Based on the Materials of the GARO

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Yuri A. Bulygin

2017-12-01

Full Text Available The article analyzes the state of the Cossack business communities of the Trade Society and MLiTAO during the revolutionary period of 1917. The expediency of scientific research for modern science and practice consists in finding the experience of work of business organizations in the acute crisis conditions of revolutionary time. The documents of the Trading Society of Don Cossacks in 1917 are confused and devoid of the former system. There are no reports of meetings of trustees, reviews of the socio-economic situation on the state of the branches of production. The main activity was aimed at the fulfillment of supplies related to military needs, the organization of self-protection of the military territories, attempts to clarify its own future under the new conditions. The work of the MLiTAO was more practical, the documents were devoted to economic issues and did not affect participation in the revolutionary events of 1917. The materials confirm the existence of an unstable situation, but do not contain information indicating a deep crisis, stopping or malfunctioning of organizations. This is due to the fact that large-scale military operations on the Don began after 1917. Separate cases of transition to a natural exchange or violation of supply contracts can not affirmatively answer the question of feudalization or the nature of the changes in capitalist relations in the region. Don entrepreneurs perceived political transformations as an update of the political system, democratic changes.

Monographs in Tang Official Historiography: Perspectives from the Technical Treatises of the History of Sui (Sui shu)

OpenAIRE

Morgan, Daniel Patrick; Chaussende, Damien

2018-01-01

Finished in 656 as part of a larger project, the ten ‘treatises’ (zhi) of the current History of Sui (Sui shu) provide us with histories of such fields of technical knowledge as astronomy, astrology, omenology, economics, law, geography, metrology, and library science covering the five divided and short-lived dynasties, 502–618 CE, that were the predecessors of the Tang. This edited volume brings together young experts in these fields to reflect upon the way that their history has been writte...

INOVAÇÃO NA AGRICULTURA BRASILEIRA: UMA ANÁLISE DA LITERATURA

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Jaqueline de Fátima Cardoso

2015-12-01

Full Text Available A agricultura desempenha papel importante na economia brasileira. Um elemento central para o desenvolvimento dessa atividade tanto no que tange ao crescimento econômico quanto social é a inovação. Nesse contexto, a proposta deste estudo objetiva analisar as inovações de produto, processo, organizacional e de marketing na agricultura brasileira. O estudo é de cunho teórico e analisa 32 artigos relacionados com o tema, selecionados a partir de bases de dados e de periódicos focados em inovação. Os resultados possibilitaram a criação de um esquema representativo da inovação na agricultura brasileira cujos componentes são os objetivos dos artigos, o tipo de estudo realizado, os conceitos e tipos de inovações adotados, as ferramentas e procedimentos utilizados para inovar, as principais entregas dos autores e a identificação das inovações como incremento ou diferenciação das commodities agrícolas. Concluiu-se que as pesquisas tratam dos diferentes tipos de inovação, conforme classificação do Manual de Oslo, os objetivos são voltados para aspectos técnicos ou sociais e o predomínio é de trabalhos de campo. Em suma, a inovação vem sendo acrescida tanto nas questões da produtividade quanto nas relações do homem com a terra e do desenvolvimento sustentável.

Pharmacokinetic determination of ephedrine in Herba Ephedrae and Wu Tou Tang decoctions in rats using ultra performance liquid chromatography tandem mass spectrometry.

Science.gov (United States)

Zheng, Zhijie; Yan, Tongmeng; Chen, Weiying; Ye, Ling; Tang, Lan; Liu, Zhongqiu

2012-08-01

A rapid and sensitive ultra performance liquid chromatography tandem mass spectrometry method was developed and validated for the determination and quantification of ephedrine in rat plasma samples. An Acquity UPLC BEH C18 column (1.7 μm, 2.1 mm × 50 mm) was used for chromatographic separation. Electrospray ionization in the positive mode was used, and the precursor-fragment ion pairs of m/z 166/148 and m/z 289/97 were adopted to characterize ephedrine and testosterone (internal standard), respectively. The method was validated using 10, 100 and 500 ng/mL of ephedrine. It demonstrated adequate levels of precision and accuracy, matrix effect, extraction recovery and stability. Linearity over the concentration range of 0.5-2000 ng/mL was acceptable with a correlation coefficient (r²) better than 0.990. To determine the pharmacokinetic behaviour of this sympathomimetic compound in the Sprague-Dawley rats, ephedrine hydrochloride, Herba Ephedrae single-herb and Wu Tou Tang decoctions were administered orally, and ephedrine hydrochloride was also administered by intravenous injection, and blood samples were collected over 24 h. Ephedrine was measured in plasma and pharmacokinetic parameters were determined by using the standard non-compartmental method and calculated by using Practical Pharmacokinetic Program-Version 87/97. The AUC(0-t) and T(max) values were significantly different (p Tang decoction compared to the other oral treatments, suggesting that some components in the decoction may reduce the bioavailability of ephedrine.

The construction of the spatio-temporal database of the ancient Silk Road within Xinjiang province during the Han and Tang dynasties

International Nuclear Information System (INIS)

Bi, Jiantao; Wang, Xingxing; Luo, Guilin; Zhu, Zuojia

2014-01-01

As the bridge over the Chinese and Western civilization, the ancient Silk Road has made a huge contribution to cultural, economic, political exchanges between China and western countries. In this paper, we treated the historical period of Western Han Dynasty, Eastern Han Dynasty and Tang Dynasty as the research time domain, and the Western Regions' countries that were existed along the Silk Road at the mean time as the research spatial domain. Then we imported these data into the SQL Server database we constructed, from which we could either query the attribute information such as population, military force, the era of the Central Plains empire, the significant events taking place in the country and some related attribute information of these events like the happened calendar year in addition to some related spatial information such as the present location, the coordinates of the capital and the territory by inputting the name of the Western countries. At the same time we could query the significant events, government institution in Central Plains and the existent Western countries at the mean time by inputting the calendar year. Based on the database, associated with GIS, RS, Flex, C# and other related information technology and network technology, we could not only browsing, searching and editing the information of the ancient Silk Road in Xinjiang Province during the Han and Tang Dynasties, but preliminary analysing as well. This is the combination of archaeology and modern information technology, and the database could also be a reference to further study, research and practice in the related fields in the future

The construction of the spatio-temporal database of the ancient Silk Road within Xinjiang province during the Han and Tang dynasties

Science.gov (United States)

Bi, Jiantao; Luo, Guilin; Wang, Xingxing; Zhu, Zuojia

2014-03-01

As the bridge over the Chinese and Western civilization, the ancient Silk Road has made a huge contribution to cultural, economic, political exchanges between China and western countries. In this paper, we treated the historical period of Western Han Dynasty, Eastern Han Dynasty and Tang Dynasty as the research time domain, and the Western Regions' countries that were existed along the Silk Road at the mean time as the research spatial domain. Then we imported these data into the SQL Server database we constructed, from which we could either query the attribute information such as population, military force, the era of the Central Plains empire, the significant events taking place in the country and some related attribute information of these events like the happened calendar year in addition to some related spatial information such as the present location, the coordinates of the capital and the territory by inputting the name of the Western countries. At the same time we could query the significant events, government institution in Central Plains and the existent Western countries at the mean time by inputting the calendar year. Based on the database, associated with GIS, RS, Flex, C# and other related information technology and network technology, we could not only browsing, searching and editing the information of the ancient Silk Road in Xinjiang Province during the Han and Tang Dynasties, but preliminary analysing as well. This is the combination of archaeology and modern information technology, and the database could also be a reference to further study, research and practice in the related fields in the future.

Trauma torácico: importância da antibioticoterapia sobre o tempo de internação

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Fontelles Mauro José

2001-01-01

Full Text Available No que tange a comprovada eficácia da drenagem pleural fechada, grande controvérsia ainda persiste em relação ao uso associado da antibioticoterapia. Os autores estudaram 167 pacientes, com trauma isolado do tórax, com objetivo de avaliar a importância do uso do antibiótico sobre o tempo de internação pós-drenagem pleural fechada. Dois grupos de pacientes foram incluídos num estudo longitudinal e prospectivo de acompanhamento de coortes. O grupo controle incluiu 104 pacientes sem uso da antibioticoterapia; no grupo experimental, 63 pacientes receberam a cefalotina sódica no pós-operatório (500 mg IV - 6/6 h. Entre os pacientes estudados, 12 (7.2% apresentavam trauma fechado; 98 (58.6%, ferimento por arma branca; 41 (24.6% ferida por projétil de arma de fogo e, 16 (9.6% lesões por outros agentes vulnerantes. Entre os pacientes do grupo controle o tempo médio de permanência hospitalar foi de 5.7± 3.2 dias e, no grupo com antibiótico, 5.7± 2.9 dias. Os resultados mostraram que nos pacientes que não receberam antibiótico e evoluíram com algum tipo de complicação pleuropulmonar, o tempo de internação foi, em média, 3.2 dias maior que nos demais.

Subsídios da linguística sistêmico-funcional para a abordagem de traduções de tradutores em formação

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Camila Nathália de Oliveira BRAGA

2011-07-01

Full Text Available Este trabalho analisa o desempenho de tradutores em formação, com base em produções textuais registradas em um estudo empírico. Cinco estudantes da FALE/UFMG participaram dessa pesquisa. Eles realizaram três tarefas de tradução envolvendo três textos de diferentes tipos textuais, selecionados de acordo com um grau de dificuldade crescente no que tange às relações lógico-semânticas de complexos oracionais (HALLIDAY; MATTHIESSEN, 2004. Para este estudo focalizaram-se os complexos oracionais de textos originais que se mostraram problemáticos para os sujeitos de acordo com o número e a duração das pausas registradas durante as tarefas. Os resultados permitiram que os sujeitos fossem colocados em diferentes estágios no continuum tradutor novato-experto (ALVES; GONÇALVES, 2007 com base nas traduções produzidas, no monitoramento da tarefa, na reflexão sobre os problemas encontrados e decisões tomadas para resolver os problemas.

Competitividade internacional baseada em recursos: estudo da relação entre os recursos e as estratégias de internacionalização nas maiores empresas exportadoras do setor calçadista brasileiro.

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Márcia Zabdiele Moreira

2008-01-01

Full Text Available A internacionalização de empresas se refere a uma estratégia para se obter maior presença no mercado internacional. Como as empresas precisam fazer uso de recursos estratégicos para sua inserção no mercado internacional, buscou-se responder: "Como se relacionam a evolução dos recursos estratégicos em relação às estratégias de internacionalização nas grandes empresas exportadoras do setor calçadista brasileiro?" Para a base teórica utilizou-se aclassificações dos recursos de Fahy (2002 e das estratégias de internacionalização de Sharma e Erramilli (2004. O estudo buscou resgatar o caráter dinâmico da Visão Baseada em Recursos. O método de pesquisa utilizado foi o quantitativo e de natureza explicativa. Os dados coletados referem-se ao período 2004 e 2005, com 15 grandes empresas exportadoras do setor calçadista brasileiro e foram analisados por meio de Cluster Analysis na entrada da internacionalização, na situação atual e em 2010. Concluiu-se que as empresas que utilizam estratégias de internacionalização mais complexas, no momento de entrada e no futuro, consideram mais estratégicas as capacidades organizacionais, depois os recursos tangíveis e por fim, os recursos intangíveis. Contudo, na situação atual, consideram mais estratégicas as capacidades organizacionais, depois os recursos intangíveis e por fim, os recursos tangíveis.

Crítica ao ideário neoliberal na educação: precarização e descaracterização da escola pública paulista

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José Luis Derisso

2017-12-01

Full Text Available O presente artigo tem como objetivo abordar o processo de precarização e descaracterização da escola pública paulista no contexto da aplicação sistemática de políticas neoliberais – no quadro de um projeto de reformas do estado e da educação brasileira desencadeadas a partir de meados da década de 1990 – e problematizá-lo à luz da concepção de educação e de escola pública da Pedagogia Histórico-Crítica (PHC. Priorizou-se a rede oficial de ensino paulista, em nível de educação básica, por sua condição de maior sistema público de ensino do país bem como pela própria importância econômica e política do estado de São Paulo no cenário nacional. Neoliberalismo, reforma do Estado e da Educação, precarização do trabalho docente e descaracterização da educação escolar no que tange aos seus fins constituem ingredientes de uma mesma concepção de educação e de sociedade que a PHC tem todo o aporte teórico para criticar e se contrapor, justamente porque sua concepção de sociedade, de formação do indivíduo, de educação e de papel social atribuído à escola é diametralmente oposta e antagônica à do ideário neoliberal.

O PROCESSO DE ADOLESCER NO DISCURSO DE MULHERES ADOLESCENTES DE UMA COMUNIDADE PERIFÉRICA EM MANAUS

OpenAIRE

Vilma Gomes Mourão; Rosângela Francischini

2018-01-01

O trabalho promove uma discussão acerca da adolescência no que tange às diversas formas de entendimento desse termo ao longo da história, para, assim, nos aproximarmos das concepções que mulheres adolescentes de um bairro periférico da cidade de Manaus desenvolveram acerca da adolescência. Trata-se de uma pesquisa exploratória de base qualitativa, cujos dados foram construídos com seis adolescentes entre 16 e 19 anos e analisados por meio da análise de discurso (Pêcheux). Os resultados aponta...

ANÁLISE DA PROPAGANDA DE MEDICAMENTOS EM TV ABERTA PARA O DISTRITO FEDERAL E “ENTORNO”

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Fernando Honorato

2014-12-01

Full Text Available A publicidade é uma ferramenta legítima e não é um problema, se os objetivos comerciais não ultrapassarem os limites éticos. As propagandas de medicamentos no Brasil já eram produzidas desde 1911 e promoviam a venda de medicamentos “mais ou menos” explicitamente. Entretanto, medicamentos são produtos especiais, cujas peças publicitárias requerem cuidados diferenciados no que tange os aspectos éticos e morais. O estudo objetivou investigar quais são e quantificar os ilícitos cometidos em propagandas de medicamentos veiculadas em TV Aberta para o grande público do Distrito Federal e cidades que o circundam, chamadas “Região do Entorno”. No estudo observacional, transversal e descritivo, foram monitoradas 56 propagandas, em 14h de programação, entre março de 2012 a março de 2013. A análise legal da monitoração de 40 peças incluídas na amostragem ocorreu sob a égide da Resolução de Diretoria Colegiada RDC Nº 96/2008 da Anvisa. Os resultados evidenciaram que em 100% das peças publicitárias ocorreram infrações à legislação. Em média, houve infração de quatro artigos da RDC por propaganda e no total foram sete os artigos ignorados da Legislação Sanitária. Em consonância com a literatura, os analgésicos, antigripais, anti-inflamatórios e antiácidos foram os mais divulgados. A ausência de informação sobre os cuidados/advertências, no uso, pode indicar que o medicamento seja totalmente seguro e eficaz, o que induz ao risco sanitário da automedicação irresponsável, que tem se tornado um problema de saúde pública mundial.

Competitividade Internacional Baseada em Recursos – Estudo da Relação entre os Recursos e as Estratégias de Internacionalização nas Maiores Empresas Exportadoras do Setor Calçadista Brasileiro

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Sérgio Henrique Arruda Cavalcante Forte

2007-01-01

Full Text Available A internacionalização de empresas se refere a uma estratégia para se obter maior presença no mercado internacional. Como as empresas precisam fazer uso de recursos estratégicos para sua inserção no mercado internacional, buscou-se responder: “Como se relacionam a evolução dos recursos estratégicos em relação às estratégias de internacionalização nas grandes empresas exportadoras do setor calçadista brasileiro?” Para a base teórica utilizou-se a classificações dos recursos de Fahy (2002 e das estratégias de internacionalização de Sharma e Erramilli (2004. O estudo buscou resgatar o caráter dinâmico da Visão Baseada em Recursos. O método de pesquisa utilizado foi o quantitativo e de natureza explicativa. Os dados coletados referem-se ao período 2004 e 2005, com 15 grandes empresas exportadoras do setor calçadista brasileiro e foram analisados por meio de Cluster Analysis na entrada da internacionalização, na situação atual e em 2010. Concluiu-se que as empresas que utilizam estratégias de internacionalização mais complexas, no momento de entrada e no futuro, consideram mais estratégicas as capacidades organizacionais, depois os recursos tangíveis e por fim, os recursos intangíveis. Contudo, na situação atual, consideram mais estratégicas as capacidades organizacionais, depois os recursos intangíveis e por fim, os recursos tangíveis.

Therapeutic potential of Wenshen Xiaozheng tang, a traditional Chinese medicine prescription, for treating endometriosis.

Science.gov (United States)

Zhang, Zhenzhen; Hu, Chunping; Tang, Weiwei; Gui, Tao; Qian, Ruyun; Xing, Yuxia; Cao, Peng; Wan, Guiping

2013-10-01

The objective of this study is to investigate the effect of Wenshen Xiaozheng Tang (WXT) on the development of endometriosis in a rat model. Sprague-Dawley rats in which endometriotic implants were induced were divided randomly into 3 groups. The rats in the low-dose and high-dose WXT groups were administered WXT 8.57 and 17.14 g/kg/d, respectively. The rats in the control groups received an equal volume of dissolvent, as did the sham-operated rats. After treatment for 4 weeks, WXT significantly decreased the mean lesion size as well as the peritoneal fluid and serum levels of tumor necrosis factor α and interleukin 1β. Cyclooxygenase-2, matrix metalloproteinase 9, plasminogen activator inhibitor 1, and intercellular adhesion molecule 1 messenger RNA (mRNA) levels were downregulated, and the mRNA expression of tissue inhibitor of metalloproteinase 1 was upregulated in the endometriotic lesions of WXT versus control group. Our data suggested that WXT may suppress the development of endometriosis by inhibiting the production of proinflammatory cytokines and regulating the expression of invasion-related genes in the endometriotic lesions.

Characterization of Thermophilic Halotolerant Aeribacillus pallidus TD1 from Tao Dam Hot Spring, Thailand

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Somchai Santiwatanakul

2011-08-01

Full Text Available The bacterial strain TD1 was isolated from Tao Dam hot spring in Thailand. Strain TD1 was Gram positive, rod-shaped, aerobic, motile, and endospore forming. The cell was 2.0–40 mm in length and about 0.4 mm in diameter. The optimum growth occurred at 55–60 °C and at pH 7–8. Strain TD1 was able to grow on medium containing up to 10% NaCl. The DNA G+C content was 38.9 mol%. The cellular fatty acid content was mainly C16:0, which comprised 25.04% of the total amount of cellular fatty acid. 16S rDNA showed 99% identity to Aeribacillus pallidus DSM 3670T. Bayesian tree analysis strongly supported the idea that strain TD1 is affiliated with genus Aeribacillus, as Aeribacillus pallidus strain TD1. Although the 16S rDNA of A. pallidus strain TD1 is similar to that of A. pallidus DSM 3670T, some physiological properties and the cellular fatty acid profiles differ significantly. A. pallidus strain TD1 can produce extracellular pectate lyase, which has not been reported elsewhere for other bacterial strains in the genus Aeribacillus. A. pallidus strain TD1 may be a good candidate as a pectate lyase producer, which may have useful industrial applications.

Characterization of thermophilic halotolerant Aeribacillus pallidus TD1 from Tao Dam Hot Spring, Thailand.

Science.gov (United States)

Yasawong, Montri; Areekit, Supatra; Pakpitchareon, Arda; Santiwatanakul, Somchai; Chansiri, Kosum

2011-01-01

The bacterial strain TD1 was isolated from Tao Dam hot spring in Thailand. Strain TD1 was Gram positive, rod-shaped, aerobic, motile, and endospore forming. The cell was 2.0-40 μm in length and about 0.4 μm in diameter. The optimum growth occurred at 55-60 °C and at pH 7-8. Strain TD1 was able to grow on medium containing up to 10% NaCl. The DNA G+C content was 38.9 mol%. The cellular fatty acid content was mainly C(16:0), which comprised 25.04% of the total amount of cellular fatty acid. 16S rDNA showed 99% identity to Aeribacillus pallidus DSM 3670(T). Bayesian tree analysis strongly supported the idea that strain TD1 is affiliated with genus Aeribacillus, as Aeribacillus pallidus strain TD1. Although the 16S rDNA of A. pallidus strain TD1 is similar to that of A. pallidus DSM 3670(T), some physiological properties and the cellular fatty acid profiles differ significantly. A. pallidus strain TD1 can produce extracellular pectate lyase, which has not been reported elsewhere for other bacterial strains in the genus Aeribacillus. A. pallidus strain TD1 may be a good candidate as a pectate lyase producer, which may have useful industrial applications.

Effect of Li Adsorption on the Electronic and Hydrogen Storage Properties of Acenes: A Dispersion-Corrected TAO-DFT Study

Science.gov (United States)

Seenithurai, Sonai; Chai, Jeng-Da

2016-01-01

Due to the presence of strong static correlation effects and noncovalent interactions, accurate prediction of the electronic and hydrogen storage properties of Li-adsorbed acenes with n linearly fused benzene rings (n = 3–8) has been very challenging for conventional electronic structure methods. To meet the challenge, we study these properties using our recently developed thermally-assisted-occupation density functional theory (TAO-DFT) with dispersion corrections. In contrast to pure acenes, the binding energies of H2 molecules on Li-adsorbed acenes are in the ideal binding energy range (about 20 to 40 kJ/mol per H2). Besides, the H2 gravimetric storage capacities of Li-adsorbed acenes are in the range of 9.9 to 10.7 wt%, satisfying the United States Department of Energy (USDOE) ultimate target of 7.5 wt%. On the basis of our results, Li-adsorbed acenes can be high-capacity hydrogen storage materials for reversible hydrogen uptake and release at ambient conditions. PMID:27609626

Processo de busca e recuperação de informação em ambientes organizacionais: uma reflexão teórica sobre a subjetividade da informação

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Thiciane Mary Carvalho Teixeira

Full Text Available RESUMO A recuperação eficiente de informações relevantes para o negócio organizacional ainda se constitui em um desafio para os gestores de informação, principalmente se o objetivo for incentivar e possibilitar o amplo acesso às informações geradas internamente e externamente à organização, visando realizar ações estratégicas. Nessa perspectiva, o gerenciamento da informação passou a ser uma atividade imprescindível para as organizações, ou seja, prospectar e monitorar informações que propiciem decisões e ações estratégicas, de maneira a propiciar diferenciais competitivos organizacionais. As condições de acesso e busca para a apropriação e uso de informações no contexto organizacional tornou-se uma atividade complexa devido à subjetividade da informação, característica esta que impõe ao gestor da informação desenvolver uma percepção aguçada no que tange ao mundo informacional, de maneira a atender as necessidades e demandas informacionais eficazmente.

A pausa que refresca... Tempo e espaço nas propagandas da Coca-Cola

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Ana Lúcia Furquim de Campos

2004-01-01

Full Text Available

Com base nas reflexões de Mikhail Bakhtin (1988 sobre cronótopo e nos estudos dos semióticos, principalmente no que tange ao percurso passional do sujeito, analisamos propagandas impressas e comerciais televisivos da Coca-Cola. O objetivo principal é traçar a trajetória discursiva da Coca-Cola desde sua entrada no Brasil, em 1941, até a campanha Gostoso é viver, lançada em 2001. O discurso da Coca-Cola apresenta valores positivos como a alegria, emoção e prazer. Entretanto, são eliminados valores negativos e ocultados interditos, como: Coca-Cola é um produto norte-americano e industrializado, portanto, não é natural, engorda e vicia. Constrói-se, assim, um discurso que privilegia aspectos temáticos voltados para os estados passionais eufóricos (paixão, emoção, alegria. A Coca-Cola também reforça a idéia de que está presente em todo tempo e lugar. Assim, as categorias espaço-temporais são elementos importantes para a construção de sentido de suas propagandas. Reafirmando os mesmos valores e mantendo as categorias cronotópicas para a construção de sentido de suas propagandas, a Coca-Cola consolida a idéia de onipotência, ou seja, ela tem o "poder" de refrescar, trazer alegria, provovar emoção e satisfazer prazeres. Cria-se, assim, um estilo, isto é, uma identidade calcada em categorias divinas, tais como onipresença e onipotência.

Synthesis and electrical characterization of Li0.30Ca0.35TaO3 perovskite synthesized via a polymerized complex route

International Nuclear Information System (INIS)

Quoc Nghi Pham; Vijayakumar, Murugesan; Bohnke, Claude; Bohnke, Odile

2005-01-01

The synthesis of Li 0.30 Ca 0.35 TaO 3 perovskite by a Pechini-type polymerizable precursor method is carefully described. The thermal decomposition of the precursor and the formation of a pure perovskite phase were investigated by means of differential thermal analysis-thermogravimetric analysis (DTA-TGA) and XRD techniques. A pure and well-crystallized phase has been obtained at a lower temperature and with a much shorter synthesis time than the phase obtained by conventional solid-state reaction method. The morphology of the powder after heating at 1300 deg. C was observed by laser granulometry, Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). Impedance spectroscopy data allowed us to determine the electrical properties, i.e., permittivity and dc-conductivity, of the bulk and grain boundaries. The results are discussed on the assumption of the brick layer model

A percepção dos profissionais da saúde frente à exposição a riscos químicos

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Mônica Aparecida da Silva

1997-12-01

Full Text Available Uma variedade de substâncias tóxicas são expostas todos os dias aos trabalhadores da área da saúde; tais substâncias têm ação nociva sobre os organismos biológicos podendo desencadear quadros de intoxicação. Diante de tal problemática, o estudo realizado objetivou identificar a percepção dos funcionários de uma Central de Material de um hospital de grande porte de Ribeirão Preto - SP, tendo por amostra 12 profissionais/ocupacionais de enfermagem, de ambos os sexos, com faixa etária de 23 a 55 anos. O método utilizado foi entrevistas tipo questionário. Os dados da pesquisa demonstram um desconhecimento dos trabalhadores em questão quanto à relação entre a exposição aos agentes químicos e conseqüentes danos à saúde. Em função desses dados podemos concluir que: (1 os profissionais adotam comportamento de segurança de maneira alienada; (2 encontram-se desmotivados; (3 há falta de interação e autoridade para fiscalização das medidas de controle preventivo; (4 existem falhas no processo de educação continuada. Portanto, compete ao enfermeiro maior responsabilidade no que tange ao desenvolvimento científico, evitando, assim, processos evasivos que geram a não sobrevivência da profissão.

Geórgia: Os sintomas do Cáucaso entre a Rússia e o Ocidente

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RICARDO DOS SANTOS POLETTO

2010-11-01

Full Text Available O presente artigo busca analisar os efeitos da crítica situação da Geórgia sobre a Rússia, com quem possui diversas divergências no que tange à províncias separatistas, tal como a Ossétia do Sul, com Ocidente, em especial os componentes do bloco Europeu, e com organizações internacionais. Como a OTAN.

REALISMO E TRANSCENDÊNCIA: O MAPA DAS MINAS DO GRANDE SERTAO

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Francis Utéza

1998-10-01

Full Text Available Guimarães Rosa insistiu sempre sobre o valor metafísico e religioso de seus escritos. Com base nas chaves que Rosa daria no seu discursode posse na Academia - o Hermetismo da tradição ocidental e o Taoísmo da tradição oriemal, pretende-se analisar o percurso do protagonista de Grande sertão: veredas em função dos três grandes rios de Minas: o São Francisco, o Rio das Velhas e Urucuia. Para além da geografia"realista", decripta-se o substrato transcendental.

The γ-gliadin-like γ-prolamin genes in the tribe Triticeae

Indian Academy of Sciences (India)

Supplementary data: The γ-gliadin-like γ-prolamin genes in the tribe Triticeae. Peng-Fei Qi, Cheng-Xing Le, Zhao Wang, Yu-Bin Liu, Qing Chen, Zhen-Zhen Wei, Bin-Jie Xu, Zheng-Yuan Wei,. Shou-Fen Dai, Yu-Ming Wei and You-Liang Zheng. J. Genet. 93, 35–41. Table 1. The γ-prolamin genes of diploid Triticeae species.

TENDÊNCIAS TEMÁTICAS DOS GRADUANDOS EM BIBLIOTECONOMIA: UM ESTUDO A PARTIR DOS TRABALHOS DE CONCLUSÃO DE CURSO DA UFRN

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Arthur Ferreira Campos

2015-12-01

Full Text Available Apresenta uma análise sobre os trabalhos de conclusão de curso dos graduandos do Curso de Biblioteconomia da Universidade Federal do Rio Grande do Norte, no período de 2010 a 2014. Objetivou-se verificar se há alguma tendência temática ou um ‘modismo temático’ em relação aos temas pesquisados pelos alunos, verificando-se também se há lacunas temáticas demandadas pelos graduandos do Curso de Biblioteconomia, uma vez que é um dos critérios de avaliação final para se obter o diploma para exercer a profissão. Nessa perspectiva, definiu-se quatro grandes subáreas temáticas da área de Biblioteconomia: Fundamentos Teóricos, Recursos e Serviços de Informação, Gestão de Unidades de Informação e Organização e Tratamento da Informação. Para tanto, realizou-se uma análise dos trabalhos de conclusão de curso, defendidos no período de 2010 a 2014. A amostra foi realizada no Núcleo Temático da Seca (NUT – SECA, o qual equivale a um centro de documentação arquivístico localizado na própria Universidade, e na Biblioteca Digital de Monografias da Universidade, que é o repositório digital institucional. A metodologia de natureza qualiquantitativa, do tipo descritivo exploratório, propiciou a coleta de dados, sua análise e elaboração de gráficos, a partir da problemática do estudo. Como resultado verificou-se grande tendência temática no que tange às tecnologias de informação, bem como uma lacuna em relação aos temas tradicionais como, por exemplo, Organização e Tratamento da Informação.

Responsabilidade civil das empresas de construção civil pelos vícios e defeitos do produto

OpenAIRE

Guedes Júnior, Alberto Augusto

2013-01-01

Responsabilidade civil das empresas de construção civil pelos vícios e defeitos do produto. A discussão ocorre através da análise rápida da evolução do sistema da responsabilidade civil o ordenamento geral e na legislação do consumidor, considerando o afastamento da teoria da culpa e o fortalecimento da responsabilização objetiva com fundamento a boa-fé. Este conflito e interação entre os códigos no que tange a responsabilização civil pelos acidentes de consumo traça a base dos ...

O USO DA MENSURAÇÃO DE DESEMPENHO PARA A COMPARAÇÃO DOS SISTEMAS DE TRANSPORTES URBANOS PÚBLICOS

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Alvaro Luiz Neuenfeldt Júnior

2015-02-01

Full Text Available Inserido ao contexto social e demográfico das cidades, os sistemas de transportes públicos são considerados como um dos principais elementos para a dinâmica da mobilidade urbana. Atualmente, existem diversos modais capazes de realizar tal tarefa, o que torna o processo de comparação entre eles relevante, visto a relação custo-benefício do investimento necessário para a sua implantação. Portanto, a presente pesquisa objetiva propor uma modelagem capaz de realizar a avaliação entre sistemas de transportes públicos, através dos conceitos relativos aos métodos multicritérios de apoio à decisão e a mensuração de desempenho. Para a aplicação prática, utilizou-se o design urbano inspirado na cidade de Curitiba, constatando-se o BRT como o mais viável. Por fim, concluiu-se que a modelagem se mostrou coerente no que tange a verificação das possíveis condições de operação em um centro urbano, sendo capaz de possibilitar a previsão da maneira com que estes estão predispostos ao contexto em questão.

Maximização da lucratividade em produção conjunta: um caso na indústria frigorífica Maximizing the profitability in joint-production: a case in the poultry industry

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Ricardo Augusto Cassel

2006-08-01

Full Text Available O presente artigo parte do problema do cálculo de custos em indústrias de produção conjunta. Observa-se que a abordagem tradicional adotada para tratar o tema, o método do custo conjunto, apresenta limitações no que tange ao modelo adotado e aos resultados obtidos em termos da análise da lucratividade dos diferentes produtos finais. Como forma de tratar o problema apresenta-se uma abordagem alternativa baseada na Teoria das Restrições suportada por técnicas de Pesquisa Operacional. Visando mostrar as diferenças dos resultados na utilização dos dois métodos, é realizado um estudo de caso em uma unidade de abate e industrialização de aves. Os resultados obtidos, em termos da lucratividade global da operação, apresentam diferenças significativas. A abordagem da Teoria das Restrições aplicada com base na utilização de técnicas de Pesquisa Operacional demonstra-se mais eficaz do prisma da tomada de decisão.This paper discusses the problem related to the costing in joint product industries. Traditional approaches to this subject present limitations regarding the analysis of the individual profitability of each final product. This problem is discussed and an alternative approach based on the Theory of Constraints, and supported by the Operational Research, is proposed. To demonstrate the differences between this new approach and the traditional one, a case study in a poultry company is presented, and the results are discussed.

Valor justo da Tractebel Energia: uma avaliação a partir dos principais modelos de precificação de ativos

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Renato Campos

2010-01-01

Full Text Available O presente estudo teve como objetivo definir o atual valor justo da Tractebel Energia, a partir dos principais modelos de precificação de ativos. A empresa objeto foi tomada como base em função de seu crescimento estável e da facilidade de se obter dados, uma vez que é sediada na cidade de Florianópolis. Não obstante, a volatilidade com que suas ações têm sido precificadas despertou interesse. Com isso, este estudo pretendeu fornecer subsídio para a tomada de decisão de investidores, no que diz respeito à compra ou venda das ações da empresa. Para tanto, a fundamentação teórica tratou sobre o conceito de avaliação de ativos e dos principais modelos disponíveis, ressaltando suas aplicações e limitações, os quais são: avaliação contábil, relativa, modelo de dividendo descontado e fluxo de caixa descontado. No que tange ao aspecto metodológico, a pesquisa se enquadra em exploratória, descritiva, eminentemente quantitativa, estudo de campo e de caso. Além disso, fez-se uso de investigação documental, bibliográfica, entrevista e do programa Economática. Com isso, a análise de dados procurou inicialmente levantar as premissas demandadas por cada um dos modelos analisados e aplicá-los. Os resultados obtidos foram então comparados entre si e ajustados, para que houvesse uma coerência. Posteriormente, foi adotada uma média aritmética para se atribuir um valor justo à empresa. A partir dessas média definiu-se um intervalo de aceitação, em função da variabilidade dos resultados e da incerteza nas estimativas.

Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-κB activation and MAPK phosphorylation.

Science.gov (United States)

Kim, Seon Young; Park, Sang Mi; Hwangbo, Min; Lee, Jong Rok; Byun, Sung Hui; Ku, Sae Kwang; Cho, Il Je; Kim, Sang Chan; Jee, Seon Young; Park, Sook Jahr

2017-01-13

Cheongsangbangpung-tang (CBT) is a traditional herbal formula used in Eastern Asia to treat heat-related diseases and swellings in the skin. The present study was conducted to evaluate the anti-inflammatory effects of cheongsangbangpung-tang extract (CBTE) both in vitro and in vivo. The in vitro effects of CBTE on the lipopolysaccharide (LPS)-induced production of inflammation-related proteins were examined in RAW 264.7 cells. The levels of nitric oxide (NO) were measured with the Griess reagent. Inflammatory cytokines and prostaglandin E 2 (PGE 2 ) were detected using the enzyme-linked immunosorbent assay (ELISA) method. Inflammation-related proteins were detected by Western blot. The effect of CBTE on acute inflammation in vivo was evaluated using carrageenan (CA)-induced paw oedema. To evaluate the anti-inflammatory effect, paw oedema volume, thickness of the dorsum and ventrum pedis skin, number of infiltrated inflammatory cells, and number of COX-2-, iNOS-immunoreactive cells were measured. In an in vitro study, CBTE inhibited the production of NO and PGE 2 and also decreased the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) activity, interleukin (IL)-1β, IL-6 and tumuor necrosis factor-α. In LPS-activated macrophages, nuclear factor-kappaB (NF-κB) and mitogen-activated protein kinase (MAPK) signalling is a pivotal pathway in the inflammatory process. These plausible molecular mechanisms increased the phosphorylation of I-κBα, while the activation of NF-κB and the phosphorylation of MAPK by LPS were blocked by CBTE treatment. In our in vivo study, a CA-induced acute oedematous paw inflammation rat model was used to evaluate the anti-inflammatory effect of CBTE. CBTE significantly reduced the increases in paw swelling, skin thicknesses, infiltrated inflammatory cells and iNOS-, COX-2 positive cells induced by CA injection. Based on these results, CBTE should favourably inhibit the acute inflammatory response through

Hwangryun-Haedok-Tang Fermented with Lactobacillus casei Suppresses Ovariectomy-Induced Bone Loss

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Ki-Shuk Shim

2012-01-01

Full Text Available Hwangryun-haedok-tang (HRT is the common recipe in traditional Asian medicine, and microbial fermentation is used for the conventional methods for processing traditional medicine. We investigated the inhibitory effect of the n-butanol fraction of HRT (HRT-BU and fHRT (fHRT-BU on the RANKL-induced osteoclastogenesis in bone-marrow-derived macrophages. mRNA expression of osteoclastogenesis-related genes were evaluated by real-time QPCR. The activation of signaling pathways was determined by western blot analysis. The marker compounds of HRT-BU and fHRT-BU were analyzed by HPLC. The inhibitory effect of HRT or fHRT on ovariectomy-induced bone loss were evaluated using OVX rats with orally administered HRT, fHRT (300, 1000 mg/kg, or its vehicle for 12 weeks. fHRT-BU significantly inhibited RANKL-induced osteoclastogenesis, and phosphorylation of p38, IKKα/β, and NF-κBp65 compared to HRT-BU. In addition, fHRT-BU also significantly inhibited the mRNA expression of Nfκb2, TNF-α, NFATc1, TRAP, ATPv0d2, and cathepsin K. Furthermore, administration of fHRT had a greater effect on the increase of BMD, and greater improved bone microstructure of the femora than that of HRT in ovariectomy rats. This study demonstrated that bacterial fermentation enhances the inhibitory effect of HRT on osteoclastogenesis and bone loss. These results suggest that fermented HRT might have the beneficial effects on bone disease by inhibiting osteoclastogenesis.

Mulher: A Quebra do Paradigma da Função Reprodutiva

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Rubia Elza Martins de Sousa

2012-03-01

Full Text Available Diante das mudanças ocorridas, busca-se uma nova configuração do espaço rural, procurando diversificar os produtos e as atividades agrícolas e não-agrícolas, visto que ambas se configuram capazes de promover a inserção dos produtores rurais nas atividades desenvolvidas. Entretanto surge a necessidade de buscar alternativas para complementação da renda, uma vez que a baixa produtividade e a falta de organização faz a produção insuficiente para manter as famílias no campo. É neste contexto que surgem as atividades pluriativas, com o objetivo de dar suporte financeiro às famílias, no que tange a ser um elemento suplementar a renda familiar, gerando assim a melhoria da qualidade de vida e fixando essas famílias no campo. Neste sentido nota-se a importância de analisar o papel das mulheres frente ao desenvolvimento de atividades pluriativas no campo, pois atualmente percebe-se uma modificação do papel feminino dentro do contexto familiar rural, visto que essas eram percebidas apenas com papel reprodutivo, papel esse que era desempenhado apenas no âmbito doméstico e que se relaciona em síntese aos afazeres domésticos e ao cuidado com os filhos, enquanto que aos homens cabe o papel produtivo por estarem diretamente ligados ao desenvolvimento da agricultura e pecuária, atividades estas que geram renda monetária; mas atualmente esse fato tem sofrido modificações, pois as mulheres rurais estão cada vez mais inseridas no mercado de trabalho por meio do desenvolvimento de atividades pluriativas, sendo assim é gerada renda complementar a família através do trabalho feminino, de forma que a mulher passa a ter além do papel reprodutivo o papel produtivo pelo fato de gerar renda por meio de seu desempenho no desenvolvimento de atividades de cunho não-agrícola.

“Não é de verdade, é só um desenho”: de que nos falam os desenhos infantis?

OpenAIRE

Bordin, Francine Borges

2014-01-01

Este trabalho investiga os desenhos infantis enquanto objeto de pesquisa educacional e está centrado nos desenhos produzidos por alunos de educação infantil de uma escola de arte e infância da cidade de Pelotas. A temática foca-se na discussão sobre desenhos infantis a partir da sociologia da infância no diálogo com a educação. Como objetivo geral, pretendemos identificar os diferentes elementos representados pelas crianças nos seus desenhos, no que tange aos temas da educação (escolar ou não...

Análise microestrutural e tenacidade ao impacto da ZAC do aço inoxidável ferrítico com 11%Cr

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Temístocles de Sousa Luz

2013-09-01

Full Text Available O aço inoxidável ferrítico possibilita, em função de suas características, o uso em diversos campos da engenharia. Dentre esses é possível citar a industria do petróleo e gás, de celulose açucareira, de transporte, entre outras. Atualmente, o desenvolvimento de novas ligas para a substituição dos aços ao carbono no que se refere ao setor de transporte de carga, levou muitos fabricantes a adotarem a liga ferrítica com base de cromo entre 11% e 12%, implementando a tal situação, uma maior vida util. A utilização dessa nova classe de aço inoxidável ferrítico gera uma demanda no que tange à pesquisas das soldas desses aços. Neste trabalho, buscou-se analisar a região soldada de um aço inoxidável ferrítico experimental contendo 11% de cromo, realizando para tal um estudo de sua microestrutura, e tenacidade ao impacto do metal de base e da zona afetada pelo calor (ZAC. A avaliação mostrou bons resultados nas propriedades mecânicas medidas nas duas regiões analisadas. Entretanto, verificou-se uma perda acentuada da tenacidade ao impacto na ZAC em relação ao metal de base.

Você é o que Você Vende: A Influência da Personalidade de Marca no Relacionamento com Clientes de Empresas de Fast-Food

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Fernanda Delmondez

2017-09-01

Full Text Available A literatura em marketing indica que, cada vez mais, as marcas precisam encontrar meios de se diferenciar dos concorrentes e de conquistar a lealdade dos consumidores, contexto em que o desenvolvimento do relacionamento entre marcas e clientes recebe conotação especial, por constituir uma fonte de diferenciação competitiva, aliado à orientação da preferência e do consumo exercida pela personalidade de marca. Assim, o estudo da relação entre personalidade de marca e relacionamento com clientes torna-se pertinente, sendo o mote principal do desenvolvimento deste artigo. No que tange ao seu objetivo principal, propõe-se avaliar a relação entre a personalidade de marcas de fast food e a percepção de relacionamento que os clientes tem com tais marcas. Para tanto, realizou-se um estudo quantitativo com 367 clientes de empresas de alimentação fast food, cujos resultados foram analisados por meio de regressão múltipla linear, de forma que as dimensões de personalidade "Credibilidade” e “Audácia" foram os melhores preditores das dimensões de percepção de relacionamento “Lealdade” e “Atendimento ao Cliente”, respectivamente. Concernente à contribuição acadêmica desta pesquisa, buscou-se complementar uma lacuna na literatura voltada à investigação da relação entre as variáveis. Em que pese as contribuições práticas, haja vista que o marketing faz parte das ciências sociais aplicadas, este estudo pode ser uma ferramenta relevante para diagnosticar o relacionamento dos consumidores com estas, auxiliando na tomada de decisão em relação à diferenciação da imagem e aprimoramento da experiência com as marcas.

Um ensaio sobre as forças que modelam a dinâmica da contabilidade gerencial em empresas prestadoras de serviços

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LAURO BRITO DE ALMEIDA

2011-11-01

Full Text Available Os serviços respondem por parcela significativa da produção de riquezas dos principais centros econômicos do mundo e pela geração e oferta de empregos. A identificação e desenvolvimento de artefatos gerenciais para atender às necessidades de gestão das empresas prestadoras de serviços têm se apresentado como um desafio para o ramo de conhecimento da Contabilidade Gerencial. Ancorado na importância dessa área do conhecimento para a gestão e competitividade das organizações, o objetivo desta pesquisa é identificar quais são as forças que modelam a Contabilidade Gerencial em empresas prestadoras de serviços. Este estudo é um ensaio enquanto estratégia de pesquisa. Os serviços, da mesma forma que os produtos tangíveis, possuem um ciclo de vida que usualmente compreende: introdução, crescimento, maturidade e declínio. Conforme o estágio do ciclo de vida do serviço, a sua gestão requer variadas estratégias de marketing, finanças e produção. As considerações finais desta investigação destacam que a Contabilidade Gerencial desempenha diversas funções. A cada etapa do ciclo de vida do serviço, novas estratégias são requeridas, impondo, às vezes, alterações na estrutura organizacional. Por fim, são aspectos que formam o leque de fatores indutores da dinâmica e adaptação dos sistemas de Contabilidade Gerencial.

As ferramentas da gestão social utilizada pelas organizações que prestam serviços sociais à comunidade e pertencem à microrregião do extremo Oeste do Estado de Santa Catarina

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Wieczynski, Marineide

2005-01-01

Full Text Available O presente artigo aborda resultados de uma pesquisa de iniciação científica que teve como objetivo identificar e relatar quais são as ferramentas da gestão social utilizada pelas organizações que prestam serviços sociais e pertencem à microrregião do extremo oeste do Estado de Santa Catarina. O tipo de pesquisa foi de natureza quali-quantitativa, com o uso de questionários semi-estrutrados, amostragem por acessibilidade e um universo de 30 ONGs, cujos sujeitos foram os gestores dessas organizações. Constatou-se que nenhuma das organizações pesquisada utiliza plenamente as ferramentas da gestão social. O não uso das ferramentas – planejamento, organização, direção e controle/avaliação – comprometem a eficiência, a eficácia e a efetividade dos programas e projetos que vem sendo desenvolvidos por elas. Sugere-se a elaboração de um projeto de extensão e/ou de filantropia, no qual o Curso de Serviço Social da UNOESC – São Miguel do Oeste possa prestar assessoria e consultoria no que tange à gestão social de ONGs

Enhanced Bone Tissue Regeneration by Porous Gelatin Composites Loaded with the Chinese Herbal Decoction Danggui Buxue Tang.

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Wen-Ling Wang

Full Text Available Danggui Buxue Tang (DBT is a traditional Chinese herbal decoction containing Radix Astragali and Radix Angelicae sinensis. Pharmacological results indicate that DBT can stimulate bone cell proliferation and differentiation. The aim of the study was to investigate the efficacy of adding DBT to bone substitutes on bone regeneration following bone injury. DBT was incorporated into porous composites (GGT made from genipin-crosslinked gelatin and β-triclacium phosphates as bone substitutes (GGTDBT. The biological response of mouse calvarial bone to these composites was evaluated by in vivo imaging systems (IVIS, micro-computed tomography (micro-CT, and histology analysis. IVIS images revealed a stronger fluorescent signal in GGTDBT-treated defect than in GGT-treated defect at 8 weeks after implantation. Micro-CT analysis demonstrated that the level of repair from week 4 to 8 increased from 42.1% to 71.2% at the sites treated with GGTDBT, while that increased from 33.2% to 54.1% at GGT-treated sites. These findings suggest that the GGTDBT stimulates the innate regenerative capacity of bone, supporting their use in bone tissue regeneration.

A nova genética para além da gestão de riscos e promoção da saúde: prolegômenos ao conceito de Biodesign The new genetics beyond of risk management and promotion of health: introduction to the concept of Biodesign

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Murilo Mariano Vilaça

2011-01-01

Full Text Available A nova genética apontaria para uma nova era da metamorfose do humano, que seria marcada pelo protagonismo desse na seleção e aperfeiçoamento da sua natureza. Assim, o human enhancement tornaria-se uma realidade antropotécnica tangível. Esse artigo, inserido em uma pesquisa do campo da Ethics of Enhancement Human Beings, pretende excogitar um novo conceito para compreender nuances da chamada Genetic Age até agora aparentemente negligenciadas por outros dois conceitos já disponíveis, a saber, biopolítica e biossociabilidade. Para tanto, recorremos à revisão de parte da bibliografia sobre o tema e à análise e crítica desses conceitos, os quais focalizam a temática fundamentalmente através das noções de gestão de riscos e promoção da vida saudável. O objetivo foi apontar a parcial pertinência da grade de inteligibilidade fornecida por eles para compreender a nova genética. Destarte, apresentamos o conceito de biodesign como uma alternativa complementar. Com ele, esperamos oferecer, introdutoriamente, um conceito que apreenda, sobretudo, o que as possibilidades de artificialização da vida humana representam para além de uma nova forma de gestão de riscos/promoção da saúde.The new genetics would point to a new era of metamorphosis of the human, which would be marked by the prominence of that in the selection and improvement of their nature. Thus, the Human Enhancement would become a tangible reality anthropo-technique. This paper, included a research of the field of Ethics Enhancement of Human Beings, intends excogitate a new concept to understand nuances called Genetic Age apparently overlooked by other already available, namely, Biopolitics and Biosociality. Therefore, we refer the review of the bibliography on Human Enhancement and the analysis and critique of these concepts, which focus on the issue mainly of risk management and promotion of healthy living. The objective was to identify the partial relevance of the

Leveduras de processos de bioetanol: potencial para a produção de cerveja especial com mosto de alta densidade

OpenAIRE

Renata Maria Christofoleti Furlan

2016-01-01

A crescente demanda por cervejas especiais tem levado o setor a buscar inovações. No âmbito da fermentação, as leveduras constituem o ponto crucial, tanto no que se refere à tolerância aos estresses do processo quanto no que tange à produção dos compostos aromáticos da bebida. Processos cervejeiros com mosto de alta densidade (high-gravity (HG)) impõem condições mais estressantes às leveduras devido à maior pressão osmótica no início da fermentação e maior teor alcoólico ao final da mesma. Le...

Anti-Inflammatory Effects of the Chinese Herbal Formula Sini Tang in Myocardial Infarction Rats

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Jiangang Liu

2014-01-01

Full Text Available The aim of this study was to evaluate the anti-inflammatory profiling of the Chinese herbal formula Sini Tang (SNT in myocardial infarction (MI rats. SNT, a decoction consisting of four herbs: Aconitum carmichaelii, Cinnamomum cassia, Zingiber officinale, and Glycyrrhiza uralensis, was characterized as a remedy to treat syndromes corresponding to heart failure and MI in China. Potential biomarkers, which reflect the extent of myocardial necrosis and correlate with cardiac outcomes following MI, such as atrial natriuretic peptide (ANP, high sensitivity C-reactive protein (hs-CRP, and proinflammatory cytokines such as tumor necrosis factor-α, interleukin-6, and interleukin-1β (TNF-α, IL-6, and IL-1β were determined in plasma, serum, and in myocardial tissue of MI rats after treatment with SNT. Our data indicate that SNT decreased significantly the levels of hs-CRP, TNF-α, IL-6, and IL-1β in MI rats. SNT decreased the expression of ANP levels in plasma and increased the vascular active marker nitric oxide, which limits vascular inflammation. In addition, SNT could decrease the expression of endothelin-1 levels in rat plasma post-MI. Our data suggest that the Chinese herbal formula SNT has the potential to improve cardiac function after MI. SNT may be a candidate for treating MI and its associated inflammatory responses.

Huangqi Jianzhong Tang for Treatment of Chronic Gastritis: A Systematic Review of Randomized Clinical Trials

Science.gov (United States)

Wei, Yue; Ma, Li-Xin; Yin, Sheng-Jun; An, Jing; Wei, Qi; Yang, Jin-Xiang

2015-01-01

To assess the clinical effects and safety of Huangqi Jianzhong Tang (HQJZ) for the treatment of chronic gastritis (CG), three English databases and four Chinese databases were searched through the inception to January 2015. In randomized controlled trials (RCTs) comparing HQJZ with placebo, no intervention and western medicine were included. A total of 9 RCTs involving 979 participants were identified. The methodological quality of the included trials was generally poor. Meta-analyses demonstrated that HQJZ plus conventional medicine was more effective in improving overall gastroscopy outcome than western medicine alone for treatment of chronic superficial gastritis with the pooling result of overall improvement [OR 3.78 (1.29,11.06), P = 0.02]. In addition, the combination of HQJZ with antibiotics has higher overall effect rate than antibiotics alone for the treatment of CG [OR 2.60 (1.49,4.54), P = 0.0007]. There were no serious adverse events reported in both the intervention and controlled groups. HQJZ has the potential of improvement of the patients' gastroscopy outcomes, Helicobacter pylori clearance rate, traditional Chinese Medicine syndromes, and overall effect rate alone or in combination use with conventional western medicine for chronic atrophic gastritis. However, due to poor methodological quality, the beneficial effect and safeties of HQJZ for CG could not be confirmed. PMID:26819622

COMPETITIVIDADE INTERNACIONAL BASEADA EM RECURSOS - ESTUDO DA RELAÇÃO ENTRE OS RECURSOS E AS ESTRATÉGIAS DE INTERNACIONALIZAÇÃO NAS MAIORES EMPRESAS EXPORTADORAS DO SETOR CALÇADISTA BRASILEIRO

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MARCIA ZABDIELE MOREIRA

2006-01-01

Full Text Available A internacionalização de empresas se refere a uma estratégia para se obtermaiorpresença no mercado internacional. Como as empresas precisam fazer uso de recursosestratégicos para sua inserção no mercado internacional,buscou-se responder: “Como serelacionam a evolução dos recursos estratégicos em relação às estratégias deinternacionalização nas grandes empresas exportadoras do setor calçadista brasileiro?” Para abase teórica utilizou-se a classificações dos recursos de Fahy (2002 e das estratégias deinternacionalização de Sharmae Erramilli (2004. O estudo buscou resgataro caráter dinâmicoda Visão Baseada em Recursos. O método de pesquisa utilizado foi o quantitativo e denatureza explicativa. Os dados coletados referem-se ao período 2004 e 2005, com 15 grandesempresas exportadoras do setor calçadista brasileiro e foram analisados por meio de ClusterAnalysis na entrada da internacionalização, na situação atual e em 2010. Concluiu-se que asempresas que utilizam estratégias de internacionalização mais complexas, no momento deentrada e no futuro,consideram mais estratégicas as capacidades organizacionais, depois osrecursos tangíveis e por fim, os recursos intangíveis. Contudo, na situação atual, considerammais estratégicas as capacidades organizacionais, depois os recursos intangíveis e por fim, osrecursos tangíveis.

Gestão da atividade e atividade da gestão: gestão como desvio

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Ana Paula Figueiredo Louzada

Full Text Available O artigo busca fazer uma análise dos processos de trabalho dos docentes de nível superior a partir de uma posição narrativa, afirmando certa política de pesquisa. Perspectivou colocar em análise o que se produz em meio ao trabalho docente. O procedimento narrativo, mesmo partindo de um caso individual, é índice singular de situações e, como agenciamento coletivo de enunciação, não remete a um sujeito. Para compor esse exercício, traz três eixos de análise: as modulações biopolíticas impressas nos modos de trabalhar no contemporâneo; a aproximação de uma docente no exercício de seu trabalho; e a apresentação de como a invenção precisa ser pensada em meio a políticas públicas. Nesse caminho, o texto parte de algumas contribuições de M. Foucault no que tange à análise do trabalho no contemporâneo, indicando uma importante inflexão nos modos como uma Psicologia do trabalho tem sido efetivada. A análise realizada, a partir da experiência com docentes, indica a importância de se apostar em uma gestão do trabalho como instância clínica, como desvio, que se constitui meio às relações de poder, meio à necessidade de produção de ruptura com o que está instituído em ambientes laborais hoje.

Comitê de Auditoria: adequação às regras da SOX, Bacen, Susep e IBGC

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Marina Schreiber de Abreu Siigor Sorrentino

2016-01-01

Full Text Available O objetivo deste estudo foi identificar qual o nível de adequação dos comitês de auditoria das empresas dos níveis diferenciados da BM&FBOVESPA às regras da SOX, Bacen, Susep e IBGC. A adequação foi analisada por meio de um check-list , construído com base nas principais normas e recomendações às quais as empresas brasileiras estão sujeitas. A análise pautou- se nas seguintes características: composição, qualificação, mandato, quantidade de reuniões, atribuições e obrigações. A pesquisa se caracterizou como descritiva, predominantemente quantitativa e documental. Compreendeu 58 empresas e abrangeu 1.508 verificações que possibilitavam identificar o nível de adequação médio de 50% (13 de 26 questões, com a máxima de 88% (23 questões e a mínima de 4% (1 questão. Os resultados apontaram que as instituições financeiras e as instituições de previdência e de seguros formam o grupo que está mais adequado às regras no que tange ao comitê de auditoria, enquanto as empresas submetidas à SOX e as demais apresentaram os índices mais baixos da amostra. Além disso, não se encontrou relação entre os níveis diferenciados de governança corporativa e o índice de adequação dos comitês, ou seja, possuir classificação no novo mercado não garante uma boa adequação às normas referentes ao comitê de auditoria.

Response to "Comment on `Solitonic and chaotic behaviors for the nonlinear dust-acoustic waves in a magnetized dusty plasma'" [Phys. Plasmas 24, 094701 (2017)

Science.gov (United States)

Zhen, Hui-Ling; Tian, Bo; Xie, Xi-Yang; Wu, Xiao-Yu; Wen, Xiao-Yong

2018-02-01

On our previous construction [H. L. Zhen et al., Phys. Plasmas 23, 052301 (2016)] of the soliton solutions of a model describing the dynamics of the dust particles in a weakly ionized, collisional dusty plasma comprised of the negatively charged cold dust particles, hot ions, hot electrons, and stationary neutrals in the presence of an external static magnetic field, Ali et al. [Phys. Plasmas 24, 094701 (2017)] have commented that there exists a different form of Eq. (4) from that shown in Zhen et al. [Phys. Plasmas 23, 052301 (2016)] and that certain interesting phenomena with the dust neutral collision frequency ν0>0 are ignored in Zhen et al. [Phys. Plasmas 23, 052301 (2016)]. In this Reply, according to the transformation given by the Ali et al. [Phys. Plasmas 24, 094701 (2017)] comment, we present some one-, two-, and N-soliton solutions which have not been obtained in the Ali et al. [Phys. Plasmas 24, 094701 (2017)] comment. We point out that our previous solutions in Zhen et al. [Phys. Plasmas 23, 052301 (2016)] are still valid because of the similarity between the two dispersion relations of previous solutions in Zhen et al. [Phys. Plasmas 23, 052301 (2016)] and the solutions presented in this Reply. Based on our soliton solutions in this Reply, it is found that the soliton amplitude is inversely related to Zd and B0, but positively related to md and α, where α refers to the coefficient of the nonlinear term, Zd and md are the charge number and mass of a dust particle, respectively, B0 represents the strength of the external static magnetic field. We also find that the two solitons are always in parallel during the propagation.

Helmet "tang" from the Metropolitan Museum of Art (New York City, United States. Features of Construction, Design and Operational Use

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Leonid A. Bobrov

2016-12-01

Full Text Available The article discusses iron helmet (No. 36.25.115, which is stored in the Metropolitan Museum of art (New York City, United States. For the first time this helmet was published and analyzed by American scientists G. C. Stone and D.G. Alexander. The analysis showed that the Bowl was made by Turkish masters of the XVII century and backplate and the hoop is added to the helmet in 1781–1782 D.G. Alexander speculated that the helmet belonged to the Warrior of the Crimean Khanate. Dating the helmet does not raise objections. However, the attribution of a helmet requires some clarification. Analysis of the design of the helmet and decoration revealed that backplate, hoop and Aventail from iron rings added to Bowl in 1781–1782, were manufactured by Circassian craftsmen living in the Northern Caucasus or in Crimea. For the decoration of the helmet has been used typical Circassian ornaments: "sieve", cherkessian floral pattern, geometric shapes, triangular in shape, "gear", etc. During Assembly of the helmet were applied characteristic of Circassian gunsmiths technological solutions: using as a basis the bowl old-style helmet, tapered Finial with a ring for a decorative plume, hoop with four plates, ringed with aventail lip to protect the forehead, etc. In Circassia similar headgear worn were known as tang (from the Arabic. "Taj", i.e., the "Crown". In the XVII–XVIII centuries. they willingly purchased representatives of Crimean Tatar nobility. Similar in design and system design helmets Circassian production belonged to the highest aristocracy of the Crimean Khanate, are stored in Museum and private collections in Poland, Turkey and the United States. The inscription "Bekmurun" on the hoop from the Metropolitan helmet suggests that it was manufactured on request of Kabardian Bekmur princely heir (Bekmurziny, which moved from Circassia in Crimea, 1737. The popularity of tang type helmets among the aristocracy of North Caucasus and Crimea were due not

Processo de intervenção junto à professora de geografia e professoras especialistas para favorecer a aprendizagem de uma aluna com surdocegueira : uma pesquisa colaborativa

OpenAIRE

Shirley Alves Godoy

2015-01-01

Esta pesquisa objetivou desenvolver um processo de intervenção por meio de uma pesquisa colaborativa, junto a uma professora regente da área de Geografia e duas especialistas em Educação Especial utilizando a cartografia tátil para favorecer a aprendizagem de uma aluna com surdocegueira/ASC, no 2º ano do ensino médio em uma escola pública no norte do Paraná. Os pressupostos teóricos da pesquisa estão sustentados nos fundamentos da educação inclusiva, especialmente no que tange à importância d...

Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING_TAO165E0N in the North Pacific Ocean and South Pacific Ocean from 2010-02-23 to 2013-02-03 (NODC Accession 0113238)

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National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0113238 includes chemical, meteorological, physical and time series data collected from MOORING_TAO165E0N in the North Pacific Ocean and South Pacific...

Tang-Luo-Ning, a Traditional Chinese Medicine, Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis of Schwann Cells under High Glucose Environment

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Weijie Yao

2017-01-01

Full Text Available Tang-Luo-Ning (TLN has a definite effect in the clinical treatment of diabetic peripheral neuropathy (DPN. Schwann cells (SCs apoptosis induced by endoplasmic reticulum stress (ER stress is one of the main pathogeneses of DPN. This study investigates whether TLN can inhibit SCs apoptosis by inhibiting ER stress-induced apoptosis. Our previous researches have demonstrated that TLN could increase the expression of ER stress marker protein GRP78 and inhibited the expression of apoptosis marker protein CHOP in ER stress. In this study, the results showed that TLN attenuated apoptosis by decreasing Ca2+ level in SCs and maintaining ER morphology. TLN could decrease downstream proteins of CHOP including GADD34 and Ero1α, while it increased P-eIF2α and decreased the upstream proteins of CHOP including P-IRE1α/IRE1α and XBP-1, thereby reducing ER stress-induced apoptosis.

Organization of the Optical Society of America Photonic Science Topical Meeting Series. Volume 3. The Microphysics of Surfaces: Beam-Induced Processes Held in Santa Fe, New Mexico on 11-13 February 1991

Science.gov (United States)

1992-05-22

as semiconductor material. Impor- tant applications are thin film solar cells, thin film transistors for liquid crystal displays, photoreceptors for...171, 1989. 307-311 3 T.MINAMI, H.NANTO and S.TAKATA, Thin Solid Films, Vol.124, 1985. 43-47 4 D.Z.DA, F.R.ZHU and H.S.TANG, Acta Energiae Solaris

Related factors of thyroid-associated ophthalmopathy in patents with Graves' disease after 131I treatment

International Nuclear Information System (INIS)

Duan Lian; Lu Keyi; Chen Xia; Zhao Deshan; Liu Jianzhong; Li Sijin; Li Xianfeng; Sun Bin

2011-01-01

Objective: To analysis the related factors of thyroid-associated ophthalmopathy(TAO) in patients with Graves' disease after 131 I treatment. Methods: Five hundred and sixty two patients with Graves' disease were followed up after 131 I treatment, included 243 cases with TAO and 319 cases without TAO. Logistic multivariate regression analysis was used to analyse the data of the improvement of the TAO, stability and progression. Results: Of the patients without TAO, 10 new cases of TAO were diagnosed (3.13%). Of the patients with TAO, 134 (55.14%) had experienced improvement, 99 (40.74%) cases with stable disease and 10 (4.12%) cases with progressed disease. The progression rate were no difference between the part of patients with and without TAO (χ 2 =0.576, P>0.05), and were difference between simple and invasive prominent eyes groups (χ 2 =11.893, P 2 =10.621, P 131 I therapy had no obviously influence between Graves' disease with and without TAO, and early controling the risk factors and treatment with glucocorticoid could prevent aggravation of TAO. (authors)

Existe um campo e um conceito no estudo da política pública efetivando a promoção da saúde?

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Antonio Rodrigues Ferreira Junior

2017-06-01

Full Text Available A crítica acerca do pensamento comum sobre política é imprescindível ao se ponderar a interface estabelecida com os saberes acadêmicos, cuja construção se dá na incerteza das ciências, na interlocução dialética entre as convergências e divergências para a formulação e/ou reformulação de conceitos, além da construção de um possível campo de estudos para as políticas públicas e suas aplicabilidades. No âmbito da promoção da saúde, é imprescindível cultivar a perspectiva ampliada de que a área é transversal ao cerne das necessidades humanas, portanto, promovê-la atualmente pressupõe o entendimento acerca das políticas públicas, com seus embates e convergências constantes em busca de modelagens que possam atender as intangíveis demandas sociais. Nessa construção dual entre o senso comum e o bojo epistêmico, o estudo da política pública não está restrito a uma disciplina acadêmica, trazendo à tona o imperativo do entendimento da área como construtora do conhecimento acadêmico em múltiplas disciplinas. Pode-se comprovar essa premissa a partir do desafio que se mostra na apresentação de teorias, métodos e ferramentas únicos para o estudo da temática(1. Essa polarização ganha vultosa importância pela urgência da tomada de decisão por gestores públicos e reverbera sobre a atual conjuntura do ensino em saúde, especialmente no que tange à sua promoção. Tem-se buscado a otimização da “expertise” como aquela que se conforma sob os auspícios da "melhor evidência científica". Nessa lógica, se precisa-se de evidência científica para o ensino de um modo geral, pode-se construir um silogismo e pensar que para o ensino das políticas públicas, com o olhar na promoção da saúde, esta premissa também seja viável. No entanto, os questionamentos sobre o ensino das políticas públicas emergem de formas avassaladoras, exigindo reflexão sobre os conceitos inerentes à área e, a partir

Os Conjurados de 1789 e a escravidão

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José Geraldo Vidigal de Carvalho

1988-12-01

Full Text Available (Primeiro Parágrafo do Artigo No que tange ao posicionamento dos Conjurados de 1879 quanto à escravidão, as opiniões dos analistas da História são divergentes. Uma vez expostas assertivas de alguns autores, chega-se, com base nos Autos de Devassa da Inconfidência Mineira e outros documentos, a conclusões que revelam o perigo de afirmativas sem a visualização global de um contexto. O diagnóstico da real situação da segunda metade do século dezoito conduz a uma pertinente compreensão da atitude dos que pugnavam ardorosamente nas Minas Colonial, por uma nova estrutura sócio-econômica.

Experiências Internacionais e Desafios dos Governos dos Países na Transição da Contabilidade Pública para o Regime de Competência

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Brenno Carvalho Botelho

2015-12-01

Full Text Available O presente estudo tem como objetivo apresentar experiências internacionais e os desafios enfrentados pelos Governos dos países na transição da contabilidade pública para o regime contábil de competência. Sua contribuição está na atualização da literatura no que tange ao posicionamento dos governos de economias mundiais quanto à adoção do accrual basis em sua contabilidade e, principalmente, por evidenciar os principais procedimentos observados durante o processo de transição. Para tratar a questão da pesquisa, são discutidos os procedimentos recomendados pelo Study 14, desenvolvido pela International Federation of Accountants (IFAC, e pelo Modelo de Requerimentos Básicos (BRM, em inglês, proposto por Ouda (2008, e analisadas as experiências monitoradas pelo IFAC nos Governos da Malásia, Malta e Suíça; as experiências relatadas na literatura (Romênia, Nova Zelândia e Austrália; e a experiência vivenciada pelo Governo brasileiro, por meio de informações coletadas no sítio da Secretaria do Tesouro Nacional do Brasil e em artigos acadêmicos. Os resultados mostram que os Governos da Suiça, Austrália e Nova Zelândia já adotam o regime de competência integral e seguiram todos os procedimentos recomendados pelo Study 14 e pelo BRM. No caso da Romênia, apesar de utilizar o regime de competência integral, não adotou a maior parte dos procedimentos recomendados, o que pode explicar o fato de as informações geradas em sua contabilidade não serem utilizadas nem pelos gestores e nem pelas autoridades governamentais. No caso dos Governos da Malásia e de Malta, definiram o ano de 2019 como data limite para a transição para o regime de competência integral. Quanto ao Brasil, adota-se o regime de competência modificado, sem previsão para adoção integral do regime de competência. Com relação aos desafios observados no processo de transição, destaca-se, nessa ordem, carência de pessoal treinado, exig

A 4-Week Repeated-Dose Oral Toxicity Study of Bojungikgi-Tang in Crl:CD Sprague Dawley Rats

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Sae-Rom Yoo

2017-01-01

Full Text Available Traditional herbal medicines have been used for centuries in Asian countries. However, recent studies have led to increasing concerns about the safety and toxicity of herbal prescriptions. Bojungikgi-tang (BJIGT, a herbal decoction, has been used in Korea to improve physical strength. To establish the safety information, BJIGT water extract was evaluated in a 4-week repeated-dose oral toxicity test in Crl:CD Sprague Dawley rats. BJIGT was orally administered in daily doses of 0, 500, 1000, and 2000 mg/kg/day for 4 weeks via oral gavage in male and female rats. We examined the mortality, clinical signs, body weight change, food intake, organ weights, hematology, serum biochemistry, and urinalysis parameters. No significant changes were observed in mortality, clinical sings, body weight, food intake, organ weights, hematology, serum biochemistry, and urinalysis parameters between the control group and the BJIGT-treated groups in the rats of both sexes. The results indicate that BJIGT did not induce toxic effects at a dose level up to 2000 mg/kg in rats. Thus, this concentration is considered the nonobservable effect dose in rats and is appropriate for a 13-week subchronic toxicity study.

A identidade social do idoso e as relações de trabalho: a realidade por trás das salvaguardas legais

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Aline Hack Moreira

2012-03-01

Full Text Available O presente trabalho aborda a questão da realidade social do idoso no mundo sócio-jurídico. Diante das salvaguardas oferecidas pelo Estado, emerge a problemática acerca da inserção social do idoso para além do alcance de salvaguardas legais, no que tange ao pertencimento. Não obstante a existência de leis e políticas direcionadas aos idosos, estas não conseguem preencher certo vazio, causado pelo pertencimento laboral. 

Renal Protective Effect of Xiao-Chai-Hu-Tang on Diabetic Nephropathy of Type 1-Diabetic Mice

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Chun-Ching Lin

2012-01-01

Full Text Available Xiao-Chai-Hu-Tang (XCHT, a traditional Chinese medicine formula consisting of seven medicinal plants, is used in the treatment of various diseases. We show here that XCHT could protect type-1 diabetic mice against diabetic nephropathy, using streptozotocin (STZ-induced diabetic mice and high-glucose (HG-exposed rat mesangial cell (RMC as models. Following 4 weeks of oral administration with XCHT, renal functions and renal hypertrophy significantly improved in the STZ-diabetic mice, while serum glucose was only moderately reduced compared to vehicle treatment. Treatment with XCHT in the STZ-diabetic mice and HG-exposed RMC resulted in a decrease in expression levels of TGF-β1, fibronectin, and collagen IV, with concomitant increase in BMP-7 expression. Data from DPPH assay, DHE stain, and CM-H2DCFDA analysis indicated that XCHT could scavenge free radicals and inhibit high-glucose-induced ROS in RMCs. Taken together, these results suggest that treatment with XCHT can improve renal functions in STZ-diabetic mice, an effect that is potentially mediated through decreasing oxidative stress and production of TGF-β1, fibronectin, and collagen IV in the kidney during development of diabetic nephropathy. XCHT, therefore merits further investigation for application to improve renal functions in diabetic disorders.

Bioinformatics Analysis for the Antirheumatic Effects of Huang-Lian-Jie-Du-Tang from a Network Perspective

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Haiyang Fang

2013-01-01

Full Text Available Huang-Lian-Jie-Du-Tang (HLJDT is a classic TCM formula to clear “heat” and “poison” that exhibits antirheumatic activity. Here we investigated the therapeutic mechanisms of HLJDT at protein network level using bioinformatics approach. It was found that HLJDT shares 5 target proteins with 3 types of anti-RA drugs, and several pathways in immune system and bone formation are significantly regulated by HLJDT’s components, suggesting the therapeutic effect of HLJDT on RA. By defining an antirheumatic effect score to quantitatively measure the therapeutic effect, we found that the score of each HLJDT’s component is very low, while the whole HLJDT achieves a much higher effect score, suggesting a synergistic effect of HLJDT achieved by its multiple components acting on multiple targets. At last, topological analysis on the RA-associated PPI network was conducted to illustrate key roles of HLJDT’s target proteins on this network. Integrating our findings with TCM theory suggests that HLJDT targets on hub nodes and main pathway in the Hot ZENG network, and thus it could be applied as adjuvant treatment for Hot-ZENG-related RA. This study may facilitate our understanding of antirheumatic effect of HLJDT and it may suggest new approach for the study of TCM pharmacology.

Evolution of the Orszag-Tang vortex system in a compressible medium. I - Initial average subsonic flow

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Dahlburg, R. B.; Picone, J. M.

1989-01-01

The results of fully compressible, Fourier collocation, numerical simulations of the Orszag-Tang vortex system are presented. The initial conditions for this system consist of a nonrandom, periodic field in which the magnetic and velocity field contain X points but differ in modal structure along one spatial direction. The velocity field is initially solenoidal, with the total initial pressure field consisting of the superposition of the appropriate incompressible pressure distribution upon a flat pressure field corresponding to the initial, average Mach number of the flow. In these numerical simulations, this initial Mach number is varied from 0.2-0.6. These values correspond to average plasma beta values ranging from 30.0 to 3.3, respectively. It is found that compressible effects develop within one or two Alfven transit times, as manifested in the spectra of compressible quantities such as the mass density and the nonsolenoidal flow field. These effects include (1) a retardation of growth of correlation between the magnetic field and the velocity field, (2) the emergence of compressible small-scale structure such as massive jets, and (3) bifurcation of eddies in the compressible flow field. Differences between the incompressible and compressible results tend to increase with increasing initial average Mach number.

Bak-Tang-Wiesenfeld model in the upper critical dimension: Induced criticality in lower-dimensional subsystems

Science.gov (United States)

Dashti-Naserabadi, H.; Najafi, M. N.

2017-10-01

We present extensive numerical simulations of Bak-Tang-Wiesenfeld (BTW) sandpile model on the hypercubic lattice in the upper critical dimension Du=4 . After re-extracting the critical exponents of avalanches, we concentrate on the three- and two-dimensional (2D) cross sections seeking for the induced criticality which are reflected in the geometrical and local exponents. Various features of finite-size scaling (FSS) theory have been tested and confirmed for all dimensions. The hyperscaling relations between the exponents of the distribution functions and the fractal dimensions are shown to be valid for all dimensions. We found that the exponent of the distribution function of avalanche mass is the same for the d -dimensional cross sections and the d -dimensional BTW model for d =2 and 3. The geometrical quantities, however, have completely different behaviors with respect to the same-dimensional BTW model. By analyzing the FSS theory for the geometrical exponents of the two-dimensional cross sections, we propose that the 2D induced models have degrees of similarity with the Gaussian free field (GFF). Although some local exponents are slightly different, this similarity is excellent for the fractal dimensions. The most important one showing this feature is the fractal dimension of loops df, which is found to be 1.50 ±0.02 ≈3/2 =dfGFF .

Desordens paralógicas e alógicas à luz da patologia cerebral

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Isaías H. Melsohn

1959-06-01

Full Text Available A revisão das investigações de Kleist sôbre a patologia cerebral mostram como suas idéias sôbre o dinamismo surgem a partir da realidade clínica. As investigações neurológicas servem de guia para as psicopatológicas. E, assim, por etapas, elaborou Kleist as noções dos "sistemas cerebrais" e seu papel no que tange às funções neurológicas e psíquicas. Uma função nervosa qualquer é assegurada pelo concurso de dois setores funcionais a que correspondem substratos anatômicos próprios; ao exercício complexo das funções da motilidade automática, por exemplo, correspondem várias estruturas anatômicas em todas as quais distinguem-se dois grupos de centros com sentido funcional diverso: um, a que cabe o papel de recepção e coordenação de estímulos, outro, de efetuação. Tal dualidade de funções primordiais é a base para o desempenho de atividades neurológicas ou psíquicas, ocorrendo tanto no setor da motilidade automática, como no da psicomotilidade, no da ação explícita, no da linguagem, no do pensamento abstrato. Foi a patologia que permitiu a Kleist a separação entre dois setores funcionais prepostos a elaboração do pensamento abstrato: aos campos 19 e 39 de Brodmann correspondem funções receptivo-coordenadoras prepostas à elaboração dos conceitos; a perturbação dessas funções conduz a uma desordem que consiste na dificuldade ou impossibilidade de elaboração dos conceitos isolados: desordem paralógia. O homem, porém, não pensa por meio de conceitos isolados; reúne-os em juízos, por meio de relações predicativas. Ê ao córtex cerebral frontal, campo 46, que dizem respeito tais funções de reunião, de efetuação do pensamento discursivo. As perturbações dessas funções, por desarranjo meramente dinâmico ou por desorganização anatômica, determinam a desordem alógica. Conquanto os dois tipos sejam encontradiços em variadas moléstias por lesão cerebral - assumindo, então, o

Análise da utilização das tecnologias da informação e comunicação na educação a distância (EaD.

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Carla Simone Pires

2017-02-01

Full Text Available A EaD se caracteriza por docentes e discentes fisicamente separados, conectados por TICs. No Brasil a EaD não é recente, entretanto, tem aumentado nos últimos anos devido a políticas públicas e à evolução das TICs, entretanto, a sua aplicação normalmente tem foco na economia de recursos. Apesar das dificuldades encontradas, é tendência mundial e converge para o uso de tecnologias. Neste sentido, TICs podem causar inclusão/exclusão social, dependendo de como sua utilização é planejadas. O mesmo ocorre com processos avaliativos, que mostram fragilidades. Os resultados permitem concluir que a transição para EaD não apresenta mudanças de práticas pedagógicas. Apesar disto, tem importante papel social, uma vez que vem suprir demandas reprimidas no que tange o acesso à educação superior, além de incentivar o desenvolvimento de municípios com Baixos Índice de Desenvolvimento Humano (IDH e Índice de Desenvolvimento da Educação Básica (IDEB. Ainda, mostra a necessidade de redimensionar as práticas de ensino (reinventando usos para TICs na transição entre ensino presencial e EaD, possibilitando que a EaD assuma sua função social na educação brasileira. Neste sentido,  Este trabalho teve como objetivo fazer um estudo analítico do contexto da Educação a Distância (EaD no Brasil, as práticas pedagógicas usadas e o papel das Tecnologias de Informação (TICs neste processo.

Desafios da contracepção juvenil: interseções entre gênero, sexualidade e saúde Challenges of youth contraception: intersections between gender, sexuality and health

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Elaine Reis Brandão

2009-08-01

Full Text Available Este artigo aborda, sob uma perspectiva socioantropológica, os desafios postos aos jovens na gestão da vida afetivo-sexual, no que tange à prevenção de gravidez imprevista. Discute algumas dificuldades por eles encontradas no manejo da contracepção, no decorrer de suas trajetórias afetivo-sexuais, identificando situações propensas à não-utilização de métodos anticonceptivos (MAC. Trata-se de pesquisa qualitativa, cujo material empírico agrupa 73 entrevistas em profundidade, com jovens de ambos os sexos, de 18 a 24 anos de idade, provenientes de três capitais do país (Salvador, Rio de Janeiro e Porto Alegre e de dois segmentos sociais (popular e médio, que passaram por ao menos um episódio de gravidez na adolescência. A análise temática dos dados reúne elementos afins e recorrentes nas narrativas juvenis, além dos contrastes de gênero e classe social. Os resultados relativos às dificuldades dos jovens de usar continuamente os MAC foram agrupados em eixos temáticos: contexto do relacionamento; relação com a família no que tange à sexualidade; efeitos colaterais dos métodos hormonais; descuido com a contracepção; dificuldades dos serviços de saúde; “falha” dos MAC; forte concepção da paternidade nos segmentos populares; uso de preservativo com parceiras “desconhecidas”; uso de coito interrompido, sem conhecimento do ciclo menstrual da parceira.This paper shows, from a social anthropological perspective, the challenges faced by young people in managing their sexual and affective lives, when it comes to preventing unexpected pregnancy. It aims to discuss some of the difficulties young people have when dealing with contraception along their sexual and affective lives and also to identify circumstances in which they tend not to use contraceptive methods. A qualitative research is presented, in which empirical data consists of 73 in-depth interviews with young people of both sex, with age ranging from 18 to

From single-site tantalum complexes to nanoparticles of Ta x N y and TaO x N y supported on silica: elucidation of synthesis chemistry by dynamic nuclear polarization surface enhanced NMR spectroscopy and X-ray absorption spectroscopy.

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Mohandas, Janet C; Abou-Hamad, Edy; Callens, Emmanuel; Samantaray, Manoja K; Gajan, David; Gurinov, Andrei; Ma, Tao; Ould-Chikh, Samy; Hoffman, Adam S; Gates, Bruce C; Basset, Jean-Marie

2017-08-01

Air-stable catalysts consisting of tantalum nitride nanoparticles represented as a mixture of Ta x N y and TaO x N y with diameters in the range of 0.5 to 3 nm supported on highly dehydroxylated silica were synthesized from TaMe 5 (Me = methyl) and dimeric Ta 2 (OMe) 10 with guidance by the principles of surface organometallic chemistry (SOMC). Characterization of the supported precursors and the supported nanoparticles formed from them was carried out by IR, NMR, UV-Vis, extended X-ray absorption fine structure, and X-ray photoelectron spectroscopies complemented with XRD and high-resolution TEM, with dynamic nuclear polarization surface enhanced NMR spectroscopy being especially helpful by providing enhanced intensities of the signals of 1 H, 13 C, 29 Si, and 15 N at their natural abundances. The characterization data provide details of the synthesis chemistry, including evidence of (a) O 2 insertion into Ta-CH 3 species on the support and (b) a binuclear to mononuclear transformation of species formed from Ta 2 (OMe) 10 on the support. A catalytic test reaction, cyclooctene epoxidation, was used to probe the supported nanoparticles, with 30% H 2 O 2 serving as the oxidant. The catalysts gave selectivities up to 98% for the epoxide at conversions as high as 99% with a 3.4 wt% loading of Ta present as Ta x N y /TaO x N y .

Governança urbana no município de Niterói-RJ: a emergência de territorialidades e conflitos em Camboinhas

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Elisabeth Rivanda Machado

2011-01-01

Este trabalho apresenta uma análise sobre as singularidades das políticas urbanas atuais e os reflexos dos novos modelos de planejamento urbano na manutenção e reprodução dos espaços de segregação da elite e da classe média alta na cidade de Niterói - RJ. Para isso, discutiremos a produção do espaço urbano em tempos de globalização, sobretudo no que tange ao advento de políticas públicas pautadas no modelo de empreendedorismo urbano e no consequente aprofundamento da fragmentação socioespacia...

Possibilidades e desafios na formação de professores de língua inglesa a indivíduos com a Síndrome de Asperger

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Eduardo Pimentel da Rocha

2016-01-01

Este trabalho tem o intuito de (re)pensar a formação de professores de inglês (LI), no que tange às suas possibilidades e os seus desafios, por meio da trans-multidisciplinaridade, mais especificamente por meio do referencial teórico da Neuroeducação, e o ensino de LI para aprendizes com a Sindrome de Asperger (SA), tendo como contexto a Universidade Estadual de Londrina (UEL) e as leis de inclusão. Para tanto, dois objetivos foram propostos, a saber: 1) Identificar se e como o curso de licen...

Chlorpromazine-induced perturbations of bile acids and free fatty acids in cholestatic liver injury prevented by the Chinese herbal compound Yin-Chen-Hao-Tang.

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Yang, Qiaoling; Yang, Fan; Tang, Xiaowen; Ding, Lili; Xu, Ying; Xiong, Yinhua; Wang, Zhengtao; Yang, Li

2015-04-16

Yin-Chen-Hao-Tang (YCHT), a commonly used as a traditional chinese medicine for liver disease. Several studies indicated that YCHT may improving hepatic triglyceride metabolism and anti-apoptotic response as well as decreasing oxidative stress .However, little is known about the role of YCHT in chlorpromazine (CPZ) -induced chlolestatic liver injury. Therefore, we aimed to facilitate the understanding of the pathogenesis of cholestatic liver injury and evaluate the effect of Yin-Chen-Hao-Tang (YCHT) on chlorpromazine (CPZ)-induced cholestatic liver injury in rats based on the change of bile acids (BAs) and free fatty acids (FFAs) alone with the biochemical indicators and histological examination. We conducted an experiment on CPZ-induced cholestatic liver injury in Wistar rats with and without YCHT for nine consecutive days. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin (ALB), total bilirubin (TBIL), total cholesterol (TC), triglycerides (TG), low density lipoprotein-cholesterol (LDL-C) were measured to evaluate the protective effect of YCHT against chlorpromazine (CPZ)-induced cholestatic liver injury. Histopathology of the liver tissue showed that pathological injuries were relieved after YCHT pretreatment. In addition, ultra-performance lipid chromatography coupled with quadrupole mass spectrometry (UPLC-MS) and gas chromatography coupled with mass spectrometry (GC-MS) was applied to determine the content of bile acids, free fatty acids, respectively. Obtained data showed that YCHT attenuated the effect of CPZ-induced cholestatic liver injury, which was manifested by the serum biochemical parameters and histopathology of the liver tissue. YCHT regulated the lipid levels as indicated by the reversed serum levels of TC, TG, and LDL-C. YCHT also regulated the disorder of BA and FFA metabolism by CPZ induction. Results indicated that YCHT exerted a protective effect on CPZ-induced cholestasis liver injury. The variance of

Treatment of Goiter with Traditional Chinese Medicine Regimen Xing Qi Hua Ying Tang: A Clinical Study on 72 Patients with Multinodular and Diffuse Goiter.

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Yang, Ming-Li; Lu, Bo

2018-04-01

The present work aimed to further explore the therapeutic potential of Xing Qi Hua Ying Tang (XQHYT) by conducting a systemic clinical study in patients with goiter. Seventy-two patients with either multinodular or diffuse goiter were enrolled and randomly assigned into treatment group receiving XQHYT (n = 36) and control group receiving Hai Zao Yu Hu Tang (n = 36). Traditional Chinese Medicine Hospital of Shanxi. Patients were diagnosed multinodular goiter or diffuse goiter resulting from Qi stagnation. All patients took the extract twice a day (100 mL each time) for two courses of treatment, of which a single course lasted for 3 months. Before the treatment was commenced and after the completion of the treatment, general body checks, thyroid function test, and goiter size examination were performed. Scoring of the clinical symptoms using Chinese medicine symptomatology was also done. The symptom score of the treatment group was significantly lower than that of the control group (treatment group, 8.26 ± 2.62; control group, 10.02 ± 2.62; p < 0.05). Substantial reduction in goiter size was seen in 82.3% of XQHYT-treated patients, whereas in the control group only 67.7% of patients exhibited constricted goiter. When assessed by both the Chinese medicine criteria and goiter size, the overall effective rate of the treatment group was 91.2%, whereas that of the control group was only 67.7%. The difference was statistically significant (p < 0.05). XQHYT did not affect the normal functions of liver, kidney, and heart. For both groups of patients, their levels of thyroid-stimulating hormone, free T4 and free T3 were normal before the treatment, and were not affected by the treatment. XQHYT was shown to be a promising therapeutic regimen for the treatment of goiter. The herbal regimen ameliorated clinical symptoms of patients that were accompanied with reduction in the size of goiter.

Integrated pharmacokinetics of major bioactive components in MCAO rats after oral administration of Huang-Lian-Jie-Du-Tang.

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Zhu, Huaxu; Qian, Zhilei; Li, Huan; Guo, Liwei; Pan, Linmei; Zhang, Qichun; Tang, Yuping

2012-05-07

Huang-Lian-Jie-Du-Tang (HLJDT, or Oren-gedoku-to in Japanese), an important multi-herb remedy in China and other Asia countries, has been used clinically to treat cerebral ischemia for decades. According to the previous studies we have reported, an HPLC method was developed and validated for determination of berberine, palmatine, baicalin, baicalein and geniposide simultaneously in MCAO rat plasma after administration of HLJDT aqueous extract. A classified integral pharmacokinetic method was put forward after having compared the integrated concentration-time profile with that of single component. An AUC based weighting approach was used for integrated principle. The results indicated the classified integral pharmacokinetic profile of index components from HLJDT could reveal the pharmacokinetic behavior of original components, and was corresponding to the holistic pharmacological effects of anti-ischemia with HLJDT. This study was aimed to explore an approach that could be applied to integrate the pharmacokinetic behavior of different components derived from HLJDT. The integrated pharmacokinetic results also provided more information for further understanding of the clinical cerebrovascular disease in use of HLJDT. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Evaluation on the Pharmacological Effect of Traditional Chinese Medicine SiJunZiTang on Stress-Induced Peptic Ulcers.

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Chen, Chiu-Mei; Lee, Chien-Ying; Lin, Po-Jung; Hsieh, Chin-Lang; Shih, Hung-Che

2013-01-01

Purpose. To explore the effects of SiJunZiTang (SJZT) on central neurotransmitters and the inhibition of HCl hypersecretion, along with the role of the vagus nerve. From this, the effects of SJZT and its constituent ingredients on inhibiting stress-induced peptic ulcers will be determined. Methods. Methods used to determine SJZT's effectiveness included (1) measuring the antipeptic ulcer effects of varying combinations of the constituents of SJZT; (2) evaluations of monoamine (MA) level in the brain; and (3) measuring the effects of longer-term SJZT treatment. Results. Comparing the control and experimental groups where the rats' vagus nerves were not cut after taking SJZT orally (500 mg/kg and 1000 mg/kg), the volume of enterogastric juice, free HCl and total acidity all reduce dose-dependently. The group administered SJZT at 1000 mg/kg showed significant reductions (P cure rate of 34.53%. Conclusion. The results display a correlation between the therapeutic effects of SJZT on stress-induced peptic ulcers and central neurotransmitter levels. Further to this, SJZT can inhibit the hypersecretion of HCl in the stomach, thus inhibiting stress-induced peptic ulcers.

Advancing Drug Discovery and Development from Active Constituents of Yinchenhao Tang, a Famous Traditional Chinese Medicine Formula

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Aihua Zhang

2013-01-01

Full Text Available Traditional Chinese medicine (TCM formula has been playing a very important role in health protection and disease control for thousands of years. Guided by TCM syndrome theories, formula are designed to contain a combination of various kinds of crude drugs that, when combined, will achieve synergistic efficacy. However, the precise mechanism of synergistic action remains poorly understood. One example is a famous TCM formula Yinchenhao Tang (YCHT, whose efficacy in treating hepatic injury (HI and Jaundice syndrome, has recently been well established as a case study. We also conducted a systematic analysis of synergistic effects of the principal compound using biochemistry, pharmacokinetics and systems biology, to explore the key molecular mechanisms. We had found that the three component (6,7-dimethylesculetin (D, geniposide (G, and rhein (R combination exerts a more robust synergistic effect than any one or two of the three individual compounds by hitting multiple targets. They can regulate molecular networks through activating both intrinsic and extrinsic pathways to synergistically cause intensified therapeutic effects. This paper provides an overview of the recent and potential developments of chemical fingerprinting coupled with systems biology advancing drug discovery towards more agile development of targeted combination therapies for the YCHT.

Alterations in Pharmacokinetics of Gemcitabine and Erlotinib by Concurrent Administration of Hyangsayukgunja-Tang, a Gastroprotective Herbal Medicine.

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Kim, Tae Hwan; Shin, Soyoung; Kim, Sarah; Bulitta, Jürgen B; Weon, Kwon-Yeon; Joo, Sang Hoon; Ma, Eunsook; Yoo, Sun Dong; Park, Gi-Young; Kwon, Dong Rak; Jeong, Seok Won; Lee, Da Young; Shin, Beom Soo

2017-09-10

Gemcitabine and erlotinib are the chemotherapeutic agents used in the treatment of various cancers and their combination is being accepted as a first-line treatment of advanced pancreatic cancer. Hyangsayukgunja-tang (HYT) is a traditional oriental medicine used in various digestive disorders and potentially helpful to treat gastrointestinal adverse effects related to chemotherapy. The present study was aimed to evaluate the effect of HYT on the pharmacokinetics of gemcitabine and erlotinib given simultaneously in rats. Rats were pretreated with HYT at an oral dose of 1200 mg/kg/day once daily for a single day or 14 consecutive days. Immediately after pretreatment with HYT, gemcitabine and erlotinib were administered by intravenous injection (10 mg/kg) and oral administration (20 mg/kg), respectively. The effects of HYT on pharmacokinetics of the two drugs were estimated by non-compartmental analysis and pharmacokinetic modeling. The pharmacokinetics of gemcitabine and erlotinib were not altered by single dose HYT pretreatment. However, the plasma levels of OSI-420 and OSI-413, active metabolites of erlotinib, were significantly decreased in the multiple dose HYT pretreatment group. The pharmacokinetic model estimated increased systemic clearances of OSI-420 and OSI-413 by multiple doses of HYT. These data suggest that HYT may affect the elimination of OSI-420 and OSI-413.

Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO rats.

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Zhu, Huaxu; Qian, Zhilei; He, Feng; Liu, Mengzhu; Pan, Linmei; Zhang, Qichun; Tang, Yuping

2013-07-15

Our previous studies showed that after oral administration of an Huang-Lian-Jie-Du-Tang (HLJDT) decoction, there is a higher concentration of the pure components, berberine, baicalin and gardenoside in the plasma of Middle cerebral artery occlusion (MCAO) rats than in sham-operated rats, The aim of the present study was to determine whether these components could be reliably measured in MCAO rat tissues. First, the plasma concentration-time profiles of berberine, palmatine, baicalin, baicalein and gardenoside were characterised in MCAO rats after oral administration of the aqueous extract of HLJDT. Subsequently, liver, lung and kidney tissues were obtained from sudden death MCAO rats in the absorption phase (0.25 h), the distribution phase (1.0 h) and the elimination phase (8.0 h) after administration of the HLJDT aqueous extract. An HPLC method was developed and validated for the determination of the distribution characteristics of berberine, palmatine, baicalin, baicalein and gardenoside simultaneously from the above-mentioned rat tissues. The results indicated that berberine, palmatine, baicalin and baicalein distributed rapidly and accumulated at high levels in the lung, while gardenoside distributed widely in the lung and the kidney. To the best of our knowledge, this is the first report to describe the distribution of the active ingredients derived from HLJDT in MCAO rat tissues. The tissue distribution results provide a biopharmaceutical basis for the design of the clinic application of HLJDT in cerebrovascular disease. Copyright © 2012 Elsevier GmbH. All rights reserved.

Cerebral angiographic findings in thromboangiitis obliterans

International Nuclear Information System (INIS)

No, Young J.; Lee, Eun M.; Kim, Jong S.; Lee, Deok H.

2005-01-01

Transient ischemic attacks (TIAs) or ischemic stroke may complicate thromboangiitis obliterans (TAO). However, there has been debate regarding the mechanism of ischemic stroke in TAO. We report the case of a patient with TAO who developed repeated TIAs. An angiogram showed multiple alternative areas of arterial occlusions in the distal segments of both middle cerebral arteries. Extensive collateral vessels around the occluded segment were also observed, which resembled the ''tree root'' or ''corkscrew'' vessels described in the peripheral arteries in TAO. Our patient illustrates that cerebral manifestations of TAO may occur with vascular changes that are identical with those encountered in the limb arteries in TAO. (orig.)

Effect of Sipjeondaebo-tang on cancer-induced anorexia and cachexia in CT-26 tumor-bearing mice.

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Choi, Youn Kyung; Jung, Ki Yong; Woo, Sang-Mi; Yun, Yee Jin; Jun, Chan-Yong; Park, Jong Hyeong; Shin, Yong Cheol; Cho, Sung-Gook; Ko, Seong-Gyu

2014-01-01

Cancer-associated anorexia and cachexia are a multifactorial condition described by a loss of body weight and muscle with anorexia, asthenia, and anemia. Moreover, they correlate with a high mortality rate, poor response to chemotherapy, poor performance status, and poor quality of life. Cancer cachexia is regulated by proinflammatory cytokines such as interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and tumor necrosis factor- α (TNF- α). In addition, glucagon like peptide-1 (GIP-1), peptide YY (PYY), ghrelin, and leptin plays a crucial role in food intake. In this study, we investigated the therapeutic effects of one of the traditional herbal medicines, Sipjeondaebo-tang (Juzen-taiho-to in Japanese; SJDBT), on cancer anorexia and cachexia in a fundamental mouse cancer anorexia/cachexia model, CT-26 tumor-bearing mice. SJDBT was more significantly effective in a treatment model where it was treated after anorexia and cachexia than in a prevention model where it was treated before anorexia and cachexia on the basis of parameters such as weights of muscles and whole body and food intakes. Moreover, SJDBT inhibited a production of IL-6, MCP-1, PYY, and GLP-1 and ameliorated cancer-induced anemia. Therefore, our in vivo studies provide evidence on the role of SJDBT in cancer-associated anorexia and cachexia, thereby suggesting that SJDBT may be useful for treating cancer-associated anorexia and cachexia.

Filosofia da análise da estabilidade da liquidez

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Rodrigo Antônio Chaves da Silva

2005-07-01

Full Text Available A informação foi considerada finalidade de nosso conhecimento, até o período em os pensadores e pesquisadores da contabilidade passaram a raciocinar sobre o conteúdo e o significado dos informes. Nesta busca da razão sobre os estados patrimoniais, surgiu a análise contábil que procura por meio de relações e identidades, o significado da dinâmica expressa da estaticamente na informação. O primeiro aspecto que surgiu no objeto de análise foi o estudo da liquidez, que é um dos principais exercícios do patrimônio. A estabilidade também é outro exercício básico e imprescindível, pois este é que promove o equilíbrio do organismo administrativo. A ciência contábil após a sua dignidade científica passou a trilhar caminhos esplendorosos, amparados em doutrina que permite alcançar os píncaros filosóficos. Os estudos concernentes aos aspectos de interação da estabilidade na liquidez são, complexos e somente com os recursos filosóficos da contabilidade se pode estudá-los com o panorama holístico e sublime. A filosofia da contabilidade não é alheia às suas práticas tecnológicas, podendo buscar pontos sublimes de panoramas abrangentes, para o estudo analítico da liquidez e estabilidade, observando todas as dimensionalidades e essencialidades de acontecimentos, na comprovação e orientação dos estados de ineficácia e eficácia patrimonial.

Effects of 90-Day Feeding of Transgenic Maize BT799 on the Reproductive System in Male Wistar Rats

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Qian-ying Guo

2015-12-01

Full Text Available BT799 is a genetically modified (GM maize plant that expresses the Cry1Ac gene from Bacillus thuringiensis (Bt. The Cry1Ac gene was introduced into maize line Zhen58 to encode the Bt crystal protein and thus produce insect-resistant maize BT799. Expression of Bt protein in planta confers resistance to Lepidopteran pests and corn rootworms. The present study was designed to investigate any potential effects of BT799 on the reproductive system of male rats and evaluate the nutritional value of diets containing BT799 maize grain in a 90-day subchronic rodent feeding study. Male Wistar rats were fed with diets containing BT799 maize flours or made from its near isogenic control (Zhen58 at a concentration of 84.7%, nutritionally equal to the standard AIN-93G diet. Another blank control group of male rats were treated with commercial AIN-93G diet. No significant differences in body weight, hematology and serum chemistry results were observed between rats fed with the diets containing transgenic BT799, Zhen58 and the control in this 13-week feeding study. Results of serum hormone levels, sperm parameters and relative organ/body weights indicated no treatment-related side effects on the reproductive system of male rats. In addition, no diet-related changes were found in necropsy and histopathology examinations. Based on results of the current study, we did not find any differences in the parameters tested in our study of the reproductive system of male rats between BT799 and Zhen58 or the control.

Optimization of high pressure machine decocting process for Dachengqi Tang using HPLC fingerprints combined with the Box-Behnken experimental design.

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Xie, Rui-Fang; Shi, Zhi-Na; Li, Zhi-Cheng; Chen, Pei-Pei; Li, Yi-Min; Zhou, Xin

2015-04-01

Using Dachengqi Tang (DCQT) as a model, high performance liquid chromatography (HPLC) fingerprints were applied to optimize machine extracting process with the Box-Behnken experimental design. HPLC fingerprints were carried out to investigate the chemical ingredients of DCQT; synthetic weighing method based on analytic hierarchy process (AHP) and criteria importance through intercriteria correlation (CRITIC) was performed to calculate synthetic scores of fingerprints; using the mark ingredients contents and synthetic scores as indicators, the Box-Behnken design was carried out to optimize the process parameters of machine decocting process under high pressure for DCQT. Results of optimal process showed that the herb materials were soaked for 45 min and extracted with 9 folds volume of water in the decocting machine under the temperature of 140 °C till the pressure arrived at 0.25 MPa; then hot decoction was excreted to soak Dahuang and Mangxiao for 5 min. Finally, obtained solutions were mixed, filtrated and packed. It concluded that HPLC fingerprints combined with the Box-Behnken experimental design could be used to optimize extracting process of traditional Chinese medicine (TCM).

PROCESSOS DE GESTÃO DA INFORMAÇÃO: TRATAMENTO, RECUPERAÇÃO E USO DA INFORMAÇÃO NO MERCADO DE CAPITAIS

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Elaine Cristina Lopes

2013-06-01

Full Text Available No mercado de capitais as informações são utilizadas como subsídios para a tomada de decisão de investidores, entre as principais destacam-se as de cunho econômico, político, contábil e as referente aos resultados financeiros das empresas que possuem ações negociadas em Bolsa de Valores. Nessa perspectiva, é fundamental que os agentes envolvidos – principalmente as sociedades corretoras –, estabeleçam processos de gestão que contenham um conjunto de critérios para a organização e o tratamento das informações coletadas em jornais, agências de notícias e nas próprias empresas que negociam ações. Assim, é fundamental estabelecer rigor no que tange aos mecanismos de recuperação dessas informações, o que requer mais do que tecnologia, porquanto são necessárias ações que irão propiciar que os conteúdos informacionais sejam disponibilizados com consistência, clareza e fidedignidade, de forma que os usuários possam recuperá-los em tempo hábil. Além disso, esses processos devem proporcionar o uso eficiente das informações recuperadas pelos usuários, de modo que possam utilizá-las visando subsidiar as decisões de compra ou venda de ações. Considerando que os sistemas de informação são responsáveis pela disseminação de informações no âmbito do mercado de capitais, é preciso apresentar quesitos que contemplem o conjunto organização, tratamento, recuperação e uso de informações. Dessa forma, buscou-se evidenciar neste trabalho tais quesitos, utilizando-se como premissa os elementos propostos por Guimarães (2003 sob a perspectiva do ambiente informacional de uma sociedade corretora de valores, refletindo através do modelo utilizado, o quanto essas empresas realizam seus trabalhos considerando as dimensões da análise documentária, do tratamento informacional e dos instrumentos para recuperação e uso da informação.

Investigation on the upper Paleozoic Strata in Tang-e-Zakeen, and introducing Zakeen formation, Kuh-e Faraghan Zagros Basin, South Iran

International Nuclear Information System (INIS)

Ghavidel-Syooki, M.

1998-01-01

A thick clastic sequence is well-developed in Tang-e-Zakeen, Kuh-e-Faraghan, being situated approximately 80 Km north of Bandar Abbas. The sequence is 340 m. thick and mainly consists of sandstone, siltstone, shale and subordinate dolomitic beds. So far, this clastic sequence has been called Faraghan Formation. This rock unit lacks marine fauna and based on stratigraphic position, it was assigned to the Early Permian (Szabo and Kheradpir, 1978). Since then, a detailed palynological study has been carried out on the Faraghan Formation by the author. These studies resulted identification of numerous palynomorph taxa, including miospore and acritarch species. The known palynomorph taxa indicated that, a major part of Faraghan Formation belongs to the Devonian Period, while the rest is Early Permian. As a result, the National Iranian Stratigraphic Committee decided and agreed upon to divide the Faraghan Formation into two rock units, namely, the Zakeen Formation, embracing the Devonian strata, and Faraghan Formation for the Early Permian sequence in the Zagros Basin respectively. The Zakeen Formation derives from the Zakeen Village which is located in the southern flank of Kuh-e-Faraghan, about 80 km north of Bandar Abbas. The type section of Zakeen Formation attains a thickness of 285m. in Tang-e-Zakeen, Kuh-e-Faraghan, approximately 23 Km from the Zakeen village. It disconformably rests on the Sarchahan Formation, while it too, disconformably overlain by the Faraghan Formation. A total of 100 samples from the Zakeen Formation were selected and treated in the palynological laboratory of the Exploration Division of National Iranian Oil Company. 63 palynomorph taxa were encountered from the Zakeen Formation. The known species were arranged in five local stratigraphic assemblage zones. Zones I and II occur in a thickness of 96 m. of the Zakeen Formation, in ascending order, suggesting the Early Devonian whereas Zones III and IV occur Within 156 m. interval of the Zakeen

Preliminary Geologic Map of the Vermejo Peak area, Colfax and Taos Counties, New Mexico and Las Animas and Costilla Counties, Colorado

Science.gov (United States)

Fridrich, Christopher J.; Shroba, Ralph R.; Pillmore, Charles L.; Hudson, Adam M.

2009-01-01

This geologic map covers four 7.5-minute quadrangles-The Wall, NM-CO (New Mexico-Colorado), Vermejo Park, NM-CO, Ash Mountain, NM, and Van Bremmer Park, NM. The study area straddles the boundary between the eastern flank of the Sangre de Cristo Mountains and the western margin of the Raton Basin, with about two-thirds of the map area in the basin. The Raton Basin is a foreland basin that formed immediately eastward of the Sangre de Cristo Mountains during their initial uplift, in the Late Cretaceous through early Eocene Laramide orogeny. Subsequently, these mountains have been extensively modified during formation of the Rio Grande rift, from late Oligocene to present. The map area is within that part of the Sangre de Cristo Mountains that is called the Culebra Range. Additionally, the map covers small parts of the Devil's Park graben and the Valle Vidal half-graben, in the northwestern and southwestern parts of the map area, respectively. These two grabens are small intermontaine basins, that are satellitic to the main local basin of the Rio Grande rift, the San Luis Basin, that are an outlying, early- formed part of the rift, and that separate the Culebra Range from the Taos Range, to the southwest.

Conjecturas da Epistemológia Jurídica e Aspectos da Teoria da Linguagem

OpenAIRE

Oliveira, Rita de Cássia Cartelli de; Cesumar; Motta, Ivan Dias; Cesumar

2008-01-01

Apresentar-se-ão reflexões em torno da epistemologia jurídica e alguns aspectos da teoria da linguagem; a necessidade de acompanhamento e aprimoramento da linguagem jurídica, para que o direito não se distancie da realidade, mantendo-se apenas como um sistema do status quo; uma breve análise de algumas teorias da ciência do direito e da linguagem; as especificidades dos termos lingüísticos para a análise da ciência do direito, pautada na contemporaneidade sob a perspectiva humanista, buscando...

Discovery of estrogen receptor α modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells.

Science.gov (United States)

Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao

2012-01-01

The binding between the estrogen receptor α (ER-α) and a variety of compounds in traditional Chinese formulae, Si-Wu-Tang (SWT) series decoctions, was studied using a stably-transfected human breast cancer cell line (MVLN). In 38 compounds tested from SWT series decoctions, the estrogen-like activity of 22 compounds was above 60% in 20 μg mL(-1). Furthermore, theoretical affinity of these compounds was certificated using the functional virtual screen of ER-α modulators by FlexX-Pharm. The accuracy of functional virtual screening of ER-α modulators could reach to 77.27%. The results showed that some compounds, such as organic acids and flavones in SWT series decoctions could be used as selective estrogen receptor modulators (SERMs) and could be selected for further development as potential agents for estrogen related diseases. Copyright © 2011 Elsevier Ltd. All rights reserved.

Immunocompromised and immunocompetent mouse models for head and neck squamous cell carcinoma

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Lei ZG

2016-01-01

Full Text Available Zhen-ge Lei,1,* Xiao-hua Ren,2,* Sha-sha Wang,3 Xin-hua Liang,3,4 Ya-ling Tang3,5 1Department of Oral and Maxillofacial Surgery, Stomatological Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, 2Department of Stomatology, Sichuan Medical Science Academy and Sichuan Provincial People’s Hospital, 3State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, 4Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, 5Department of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People’s Republic of China *These authors contributed equally to this work Abstract: Mouse models can closely mimic human oral squamous epithelial carcinogenesis, greatly expand the in vivo research possibilities, and play a critical role in the development of diagnosis, monitoring, and treatment of head and neck squamous cell carcinoma. With the development of the recent research on the contribution of immunity/inflammation to cancer initiation and progression, mouse models have been divided into two categories, namely, immunocompromised and immunocompetent mouse models. And thus, this paper will review these two kinds of models applied in head and neck squamous cell carcinoma to provide a platform to understand the complicated histological, molecular, and genetic changes of oral squamous epithelial tumorigenesis. Keywords: head and neck squamous cell carcinoma, HNSCC, mouse models, immunocompromised models, immunocompetent models, transgenic models

A influência da rede social da nutriz no aleitamento materno: o papel estratégico dos familiares e dos profissionais de saúde The influence of the social net of lactating mothers in the breastfeeding: the strategic role of the relatives and professionals of health

Directory of Open Access Journals (Sweden)

Emanuele Souza Marques

2010-06-01

Full Text Available Objetivou-se levantar e categorizar trabalhos científicos sobre a influência da rede social da lactante no contexto da amamentação. Para isto, realizou-se uma revisão bibliográfica nas principais bases de dados em saúde (MEDLINE, LILACS, SciELO, utilizando como palavras chaves os descritores: aleitamento materno, desmame e família (e suas versões em inglês e espanhol. Foram consultados também livros, teses, dissertações, publicações em órgãos internacionais e nacionais (OMS, UNICEF, Ministério da Saúde. Pode-se observar que os atores que compõem a rede social da nutriz são capazes de exercer interferência na decisão de amamentar, através de diferentes âmbitos, tais como o incentivo/apoio à iniciativa; o repasse de conhecimentos e valores culturais; a tradição familiar e o cultivo do desinteresse/desestímulo e da pressão exercida sobre a lactante em relação à forma de alimentar a criança. Destarte, pode-se inferir sobre a necessidade de implementação de novas práticas de saúde no que tange à forma de cuidado a este grupo populacional. Vale ressaltar a importância de que os profissionais se capacitem para uma escuta sensível sobre o significado da lactação desde o olhar da nutriz. Por fim, destaca-se o papel importante da rede social da lactante, principalmente a família, para o sucesso da amamentação.The objective was to raise and classify scientific works on the influence of the social net of lactating mothers in the context of the breastfeeding. A bibliographical review was done in the main databases (MEDLINE, LILACS, SciELO, using as keywords: breastfeeding, weaning and family (and their versions in English and Spanish. Books, thesis, dissertations, and publications in international and national institutions were consulted (WHO, UNICEF, Ministry of Health. It could be observed that the actors that compose the social net of the lactating mothers can interfere in the decision of breastfeeding

Ensino da Bioética Convergente de ricardo maliandi nos Cursos de medicina

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Nalita Maria Hall Brum de Barros Mugayar

Maliandi, explicitada, no que tange à Bioética, com auxílio do médico Oscar Thüer — nos cursos de Medicina, trazendo mais segurança e menos solidão ao difícil processo de tomada de decisão inerente à relação médico-paciente ou médico-família, em especial no que se refere à atenção médica no fim da vida.

Correlative analysis of metabolite profiling of Danggui Buxue Tang in rat biological fluids by rapid resolution LC-TOF/MS.

Science.gov (United States)

Li, Chang-Yin; Qi, Lian-Wen; Li, Ping

2011-04-28

In this work, the metabolite profiles of Danggui Buxue Tang (DBT) in rat bile and plasma were qualitatively described, and the possible metabolic pathways of DBT were subsequently proposed. Emphasis was put on correlative analysis of metabolite profiling in different biological fluids. After oral administration of DBT, bile and plasma samples were collected and pretreated by solid phase extraction. Rapid resolution liquid chromatography coupled to time-of-flight mass spectrometry (RRLC-TOFMS) was used for characterization of DBT-related compounds (parent compounds and metabolites) in biological matrices. A total of 142 metabolites were detected and tentatively identified from the drug-containing bile and plasma samples. Metabolite profiling shows that rat bile contained relatively more glutathione-derived conjugates, more saponins compounds and more diverse forms of metabolites than urine. The metabolite profile in plasma revealed that glucuronide conjugates of isoflavonoids, dimmers, acetylcysteine conjugates and parent form of phthalides, as well as saponin aglycones were the major circulating forms of DBT. Collectively, the metabolite profile analysis of DBT in different biological matrices provided a comprehensive understanding of the in vivo metabolic fates of constituents in DBT. Copyright © 2011 Elsevier B.V. All rights reserved.

Regional vegetation dynamics and its response to climate change—a case study in the Tao River Basin in Northwestern China

International Nuclear Information System (INIS)

Li, Changbin; Yang, Linshan; Wang, Shuaibing; Yang, Wenjin; Zhu, Gaofeng; Qi, Jiaguo; Zou, Songbing; Zhang, Feng

2014-01-01

The 30-year normalized-difference vegetation index (NDVI) time series from AVHRR/MODIS satellite sensors was used in this study to assess the regional vegetation dynamic changes in the Tao River Basin, which cuts across the Eastern Tibetan Plateau (ETP) and the Southwestern Loess Plateau (SLP). First, principal component and correlation analyses were carried out to determine the key climatic variables driving ecological change in the region. Then, regression models were tested to correlate NDVI with the selected climatic variables to determine their predictive power. Finally, Sen’s slope method was used to determine how terrestrial vegetation has responded to regional climate change in the region. The results indicated an average winter season NDVI value of 0.14 in the ETP but only 0.04 in the SLP. Primarily driven by increasing temperature, vegetation growth has generally been enhanced since 1981; spring NDVI increased by 0.03 every 10 years in the ETP and 0.02 in the SLP. Further, results from trend analyses suggest vegetation growth in the ETP shifted to earlier-start and earlier-end dates, however in the SLP, the growing season has been extended with an earlier-start and later-end date. The precipitation threshold for vegetation germination, measured by the cumulative spring rainfall, was found to be 44 mm for both the ETP and SLP. (paper)

Massively Parallel Assimilation of TOGA/TAO and Topex/Poseidon Measurements into a Quasi Isopycnal Ocean General Circulation Model Using an Ensemble Kalman Filter

Science.gov (United States)

Keppenne, Christian L.; Rienecker, Michele; Borovikov, Anna Y.; Suarez, Max

1999-01-01

A massively parallel ensemble Kalman filter (EnKF)is used to assimilate temperature data from the TOGA/TAO array and altimetry from TOPEX/POSEIDON into a Pacific basin version of the NASA Seasonal to Interannual Prediction Project (NSIPP)ls quasi-isopycnal ocean general circulation model. The EnKF is an approximate Kalman filter in which the error-covariance propagation step is modeled by the integration of multiple instances of a numerical model. An estimate of the true error covariances is then inferred from the distribution of the ensemble of model state vectors. This inplementation of the filter takes advantage of the inherent parallelism in the EnKF algorithm by running all the model instances concurrently. The Kalman filter update step also occurs in parallel by having each processor process the observations that occur in the region of physical space for which it is responsible. The massively parallel data assimilation system is validated by withholding some of the data and then quantifying the extent to which the withheld information can be inferred from the assimilation of the remaining data. The distributions of the forecast and analysis error covariances predicted by the ENKF are also examined.

Uma abordagem jurídica à questão do ressarcimento de danos elétricos pelas distribuidoras de energia.

OpenAIRE

Ana Carolina Oliveira Salomão

2012-01-01

Com o aumento da necessidade e do consumo da energia elétrica, aliado a uma maior conscientização dos consumidores acerca de seus direitos e deveres perante a sociedade, constatou-se o surgimento de um crescente número de contendas envolvendo estes últimos e as concessionárias de energia elétrica, principalmente no que tange ao setor de distribuição de energia elétrica. Isto se deve à ocorrência de danos ocasionados por falhas na prestação do serviço público de energia elétrica, destacando-se...

Por uma 'nova pragmática emancipatória'

OpenAIRE

Ferreira,Dina Maria Martins; Alencar,Claudiana Nogueira de

2013-01-01

Neste artigo propomos o modus operandi de uma pragmática contra-hegemônica no que tange às teorias do mainstream, ou seja, as internalistas (auto-suficiência da língua como sistema) e as externalistas (aspecto social aliado à língua e não constitutivo da língua). Para tal, constroem-se dois percursos argumentativos para dar conta de uma nova Pragmática emancipatória: (1) nova, que mostra a incompatibilidade conceitual entre a teoria austiniana e a interpretada por seu discípulo Searle; (2) em...

Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

Science.gov (United States)

Yeh, Chia-Hao; Arnold, Christof K.; Chen, Yen-Hui; Lai, Jung-Nein

2011-01-01

Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS < 16, n = 34; MRS ≥ 16, n = 33). After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9) to 9.0 (±3.2) (95% confidence interval −4.93, −3.10). Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS ≥ 16). There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness). Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality. PMID:21660310

Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

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Chia-Hao Yeh

2011-01-01

Full Text Available Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI and the World Health Organization quality of life (WHOQOL. Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS<16, n=34; MRS≥16, n=33. After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9 to 9.0 (±3.2 (95% confidence interval −4.93, −3.10. Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS≥16. There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness. Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality.

[The influnence of dachengqi tang on acute lung injury and intra abdominal hypertension in rats with acute pancreatitis].

Science.gov (United States)

Wan, Mei-Hua; Li, Juan; Tang, Wen-Fu; Gong, Han-Lin; Chen, Guang-Yuan; Xue, Ping; Zhao, Xian-Lin; Xia, Qing

2011-09-01

To test the hypothesis "lung and large intestine are interior exteriorly related" through investgating into the effect of Dacheng qi tang (DCQT) on intra abdominal hypertension (IAH) and acute lung injury (ALI) in rats with acute pancreatitis. Male SD rats were randomly divided into three groups with ten rats for each group: rats with sham-operations (SO); rats with acute necrosis pancreatitis (ANP); rats with ANP plus DCQT treatment. ANP was induced by retrograde infusion of 5% taurocholic acid into pancreatic duct. Two hours after operations, 10 mL/kg of normal saline was orally adminstered to the rats in both SO and ANP groups, whereas 10 mL/kg DCQT was adminstered to the rats in the treatment group. Aterial blood, pancreas and lung tissues were collected for biomarkers and histopathology 24 hours after operations. Intra-abdominal pressure and intestinal propulsion rate were also measured. RESULTS; DCQT treatment reduced intra-abdominal pressure and improved intestinal propulsion rate compared with those treated with saline (P 0.05). Only two rats in the ANP group died. DCQT can effectively relieve IAH and cure ALI at the same time in rats with acute pancreatitis. The result provides evidence to support the hypothesis "lung and large intestine are interior exteriorly related".

Reconstruction of the 1997/1998 El Nino from TOPEX/POSEIDON and TOGA/TAO Data Using a Massively Parallel Pacific-Ocean Model and Ensemble Kalman Filter

Science.gov (United States)

Keppenne, C. L.; Rienecker, M.; Borovikov, A. Y.

1999-01-01

Two massively parallel data assimilation systems in which the model forecast-error covariances are estimated from the distribution of an ensemble of model integrations are applied to the assimilation of 97-98 TOPEX/POSEIDON altimetry and TOGA/TAO temperature data into a Pacific basin version the NASA Seasonal to Interannual Prediction Project (NSIPP)ls quasi-isopycnal ocean general circulation model. in the first system, ensemble of model runs forced by an ensemble of atmospheric model simulations is used to calculate asymptotic error statistics. The data assimilation then occurs in the reduced phase space spanned by the corresponding leading empirical orthogonal functions. The second system is an ensemble Kalman filter in which new error statistics are computed during each assimilation cycle from the time-dependent ensemble distribution. The data assimilation experiments are conducted on NSIPP's 512-processor CRAY T3E. The two data assimilation systems are validated by withholding part of the data and quantifying the extent to which the withheld information can be inferred from the assimilation of the remaining data. The pros and cons of each system are discussed.

Chemomics-Integrated Proteomics Analysis of Jie-Geng-Tang to Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Mice

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Jin Tao

2016-01-01

Full Text Available Jie-Geng-Tang (JGT, a classic and famous traditional Chinese medicine (TCM prescription composed of Platycodon grandiflorum (Jacq. A. DC. (PG and Glycyrrhiza uralensis Fisch. (GU, is well known for “clearing heat and relieving toxicity” and its ability to “diffuse the lung and relieve sore throat.” However, the mechanism underlying its action remains unclear. In this study, potential anti-inflammatory ingredients were screened and submitted to PharmMapper and the KEGG bioinformatics website to predict the target proteins and related pathways, respectively. Differentially expressed candidate proteins from acute lung injury (ALI mice treated with JGT were identified by isobaric tags for relative and absolute quantitation (iTRAQ and LC Triple-TOF. Eleven potential anti-inflammatory ingredients were found, including the derivatives of glycyrrhizic acid, licorice-saponin, liquiritin, and platycodigenin. A total of sixty-seven differentially expressed proteins were confirmed after JGT treatment with four therapeutic functions, including immunoregulation, anti-inflammation, ribosome, and muscle contraction. PG and GU comediate PI3K/Akt signal pathway inhibition of NF-κB, VCAM1, and ICAM1 release which primarily act on PI3K, PDK1, AKT, and GSK3β. GU markedly inhibits the ERK/MAPK signaling pathways and primarily acts on LCK, RAS, and MEK. A network was constructed using bioactive ingredients, targets, and pathways to determine the mechanism underlying JGT treatment of ALI.

Os desafios da televisão digital

OpenAIRE

Dors, Rosália Lara de Moura

2005-01-01

Os meios de comunicação eletrônicos vêm sendo digitalizados na maior parte do mundo, o que provocará mudanças econômicas, políticas e culturais, sem contar as modificações legais implicadas. Esta pesquisa pretende antecipar os desafios que serão enfrentados pelo Brasil, no que tange o conteúdo televisivo, ao substituir a televisão analógica pela digital. Para tanto, será analisado o Jornal Interativo, disponibilizado na Internet pela allTV uma vez que não há produção específica para a nova pl...

Automatic locking knee brace joint

Science.gov (United States)

Weddendorf, Bruce (Inventor)

1995-01-01

This invention is an apparatus for controlling the pivotal movement of a knee brace comprising a tang-and-clevis joint that has been uniquely modified. Both the tang and the clevis have a set of teeth that, when engaged, can lock the tang and the clevis together. In addition, the tang is biased away from the clevis. Consequently, when there is no axial force (i.e., body weight) on the tang, the tang is free to pivot within the clevis. However, when an axial force is exerted on the tang, the tang is pushed into the clevis, both sets of teeth engage, and the tang and the clevis lock together.

Chinese Herbal Formula, Modified Danggui Buxue Tang, Attenuates Apoptosis of Hematopoietic Stem Cells in Immune-Mediated Aplastic Anemia Mouse Model

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Jingwei Zhou

2017-01-01

Full Text Available A derivative formula, DGBX, which is composed of three herbs (Radix astragali, Radix Angelicae sinensis, and Coptis chinensis Franch, is derived from a famous Chinese herbal formula, Danggui Buxue Tang (DBT (Radix astragali and Radix Angelicae sinensis. We aimed to investigate the effects of DGBX on the regulation of the balance between proliferation and apoptosis of hematopoietic stem cells (HSCs due to the aberrant immune response in a mouse model of aplastic anemia (AA. Cyclosporine (CsA, an immunosuppressor, was used as the positive control. Our results indicated that DGBX could downregulate the production of IFNγ in bone marrow cells by interfering with the binding between SLAM and SAP and the expressions of Fyn and T-bet. This herbal formula can also inhibit the activation of Fas-mediated apoptosis, interferon regulatory factor-1-induced JAK/Stat, and eukaryotic initiation factor 2 signaling pathways and thereby induce proliferation and attenuate apoptosis of HSCs. In conclusion, DGBX can relieve the immune-mediated destruction of HSCs, repair hematopoietic failure, and recover the hematopoietic function of HSCs in hematogenesis. Therefore, DGBX can be used in traditional medicine against AA as a complementary and alternative immunosuppressive therapeutic formula.

O CORPO E O UNIVERSO LÚDICO NO DESENVOLVIMENTO DE HABILIDADES ESSENCIAIS NO PROCESSO DE LETRAMENTO E ALFABETIZAÇÃO

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Luzia Alves de Carvalho

2013-06-01

Full Text Available O trabalho “O Corpo e o Universo Lúdico no Desenvolvimento de Habilidades Essenciais no Processo de Letramento e Alfabetização” apresenta o resultado de um processo de Psicomotricidade Relacional no espaço escolar. Revela-se como estudo de caso de uma turma de 17 crianças de 5 anos, do 3º período da Educação Infantil, durante um ano. Objetiva verificar a influência da Psicomotricidade Relacional no letramento e alfabetização dessas crianças e no seu desenvolvimento integral. Tange, en passant sobre a natureza neurológica da criança como fundamento para seu processo de aprendizagem hábil, motriz, cognitiva, sócio-afetiva e espiritual.

A arte de morar... na Lua: a construção de um novo espaço de morar frente à mudança do dispositivo asilar para o Serviço Residencial Terapêutico

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Tania Kuperman Sztajnberg

2010-09-01

Full Text Available Em instituições que funcionam sob a lógica da desinstitucionalização existe um número significativo de pacientes que permanecem nos hospitais psiquiátricos. A implantação dos Serviços Residenciais Terapêuticos tornou-se uma das principais estratégias da reforma psiquiátrica. A partir do estudo de um caso clínico e os enfrentamentos encontrados neste trabalho, no que tange a passagem da internação ao SRT, aponto para a necessidade de uma escuta clínica que propicie a invenção de um espaço subjetivo que permitirá alguma circulação entre os dispositivos.

A Copa do Mundo 2014: oportunidades e prospecção geradas para a cadeia produtiva do turismo de Cuiabá MT

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Roberta Leal Raye

2013-02-01

Full Text Available Este artigo trata dos resultados parciais do estudo que tem como objeto monitorar e avaliar os serviços turísticos da cidade de Cuiabá MT pactuadas na Matriz de Responsabilidade, projetos e especificações técnicas exigidas pela da Federation Internationale de Football Association – FIFA, para realização do Megaevento da Copa do Mundo 2014. Trata-se de uma encomenda do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq que tange a área de turismo. A pesquisa tem caráter exploratória-descritiva, que se utilizará da pesquisa documental e pesquisa de campo. Os resultados iniciais demonstram insatisfação dos hoteleiros quanto ao crescimento do número de leitos em decorrência do evento. A previsão de término da pesquisa é de maio de 2014.

A utilização das mídias sociais como ferramentas para seleção e contratação de profissionais: pesquisa-diagnóstico em empresas da região de Tubarão/SC

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Marília Köenig

2014-07-01

Full Text Available O presente artigo tem como tema a utilização das mídias sociais como ferramentas (primárias ou secundárias de seleção e contratação de profissionais. O objetivo da pesquisa é, primordialmente, verificar como as mídias sociais estão presentes na vida organizacional, avaliando sua influência no momento da contratação de colaboradores. Avalia-se, ainda, de que maneira elas podem servir ao propósito de integrar a empresa aos funcionários. Para tanto, realizou-se uma pesquisa-diagnóstico em quatro empresas da região de Tubarão/SC. Como métodos de coleta de dados, são utilizados a entrevista semiestruturada, com os gestores, e um questionário com perguntas abertas e fechadas, com os colaboradores. Constatou-se, ao final, que as empresas da região de Tubarão são ainda bastante tradicionais no que tange ao processo de recrutamento e seleção de pessoas, fazendo, na maioria das vezes, uso dos métodos tradicionais de captação de talentos. Percebeu-se que, dentre as variáveis encontradas, o grau de escolaridade exigido para a vaga é critério determinante atribuído pelo gestor de RH para selecionar candidatos. Observou-se, ainda, que as mídias têm papel preponderante para as vagas nos níveis tático e estratégico das empresas em questão.  

Evaluating the Bone Tissue Regeneration Capability of the Chinese Herbal Decoction Danggui Buxue Tang from a Molecular Biology Perspective

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Wen-Ling Wang

2014-01-01

Full Text Available Large bone defects are a considerable challenge to reconstructive surgeons. Numerous traditional Chinese herbal medicines have been used to repair and regenerate bone tissue. This study investigated the bone regeneration potential of Danggui Buxue Tang (DBT, a Chinese herbal decoction prepared from Radix Astragali (RA and Radix Angelicae Sinensis (RAS, from a molecular biology perspective. The optimal ratio of RA and RAS used in DBT for osteoblast culture was obtained by colorimetric and alkaline phosphatase (ALP activity assays. Moreover, the optimal concentration of DBT for bone cell culture was also determined by colorimetric, ALP activity, nodule formation, Western blotting, wound-healing, and tartrate-resistant acid phosphatase activity assays. Consequently, the most appropriate weight ratio of RA to RAS for the proliferation and differentiation of osteoblasts was 5 : 1. Moreover, the most effective concentration of DBT was 1,000 μg/mL, which significantly increased the number of osteoblasts, intracellular ALP levels, and nodule numbers, while inhibiting osteoclast activity. Additionally, 1,000 μg/mL of DBT was able to stimulate p-ERK and p-JNK signal pathway. Therefore, DBT is highly promising for use in accelerating fracture healing in the middle or late healing periods.

Sustentabilidade: da evolução dos conceitos à implementação como estratégia nas organizações Sustainability: the evolution of concepts to implementation as strategy in organizations

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Lucas Rebello de Oliveira

2012-01-01

Full Text Available Este trabalho apresenta uma contextualização acerca da literatura e das diferentes abordagens sobre sustentabilidade nas organizações, relacionando-a com o planejamento estratégico. O estudo enquadra-se na Engenharia da Sustentabilidade, uma das áreas do conhecimento definida pela ABEPRO para a Engenharia de Produção. Adaptando os conceitos do Balanced Scorecard (BSC, são propostas diretrizes de gestão, que promovem o alinhamento entre a sustentabilidade e a estratégia, denominada Matriz de Alinhamento Estratégico Sustentável (MAES. Para avaliar a aplicabilidade, foi realizado estudo de caso em uma fabricante de cosméticos. A avaliação da aplicação das diretrizes propostas foi feita a partir da análise das práticas de gestão na organização estudada. Algumas considerações foram feitas acerca dos resultados encontrados, especialmente no que tange ao grau de desenvolvimento ambiental inerente aos processos internos, e são apontadas algumas sugestões de melhoria, no que se refere ao aprimoramento do binômio entre aprendizado e crescimento e o pilar social da sustentabilidade.This paper presents a background on the literature and different approaches to sustainability in organizations, linking it to strategic planning. The study was based on Engineering of Sustainability, one of the knowledge areas defined by ABEPRO for Production Engineering. Adapting the concepts of Balanced Scorecard (BSC, there were proposed management guidelines, which promoted the alignment between sustainability and strategy - called Matrix of Sustainable Strategic Alignment (MSSA. In order to evaluate its applicability, a case study was conducted in a cosmetics manufacturer. The assessment of the proposed guidelines implementation was made from the analysis of management practices in the studied organization. Some considerations were made about the results, especially regarding the degree of environmental development inherent to the internal

Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease

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Wei-Ming Xu

2018-01-01

-based approach was proposed to identify the underlying molecular modules of PSCS complicated with IHD, which could be used for interpreting the pharmacological mechanisms of well-established Chinese herbal formulas (e.g., Tao Hong Si Wu Tang, Dan Shen Yin, Hunag Lian Wen Dan Tang and Gua Lou Xie Bai Ban Xia Tang. In addition, these results delivered novel understandings of the molecular network mechanisms of IHD phenotype subtypes with PSCS complications, which would be both insightful for IHD precision medicine and the integration of disease and TCM syndrome diagnoses.

Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease.

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Xu, Wei-Ming; Yang, Kuo; Jiang, Li-Jie; Hu, Jing-Qing; Zhou, Xue-Zhong

2018-01-01

-based approach was proposed to identify the underlying molecular modules of PSCS complicated with IHD, which could be used for interpreting the pharmacological mechanisms of well-established Chinese herbal formulas ( e.g., Tao Hong Si Wu Tang, Dan Shen Yin, Hunag Lian Wen Dan Tang and Gua Lou Xie Bai Ban Xia Tang ). In addition, these results delivered novel understandings of the molecular network mechanisms of IHD phenotype subtypes with PSCS complications, which would be both insightful for IHD precision medicine and the integration of disease and TCM syndrome diagnoses.

Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease

Science.gov (United States)

Xu, Wei-Ming; Yang, Kuo; Jiang, Li-Jie; Hu, Jing-Qing; Zhou, Xue-Zhong

2018-01-01

-based approach was proposed to identify the underlying molecular modules of PSCS complicated with IHD, which could be used for interpreting the pharmacological mechanisms of well-established Chinese herbal formulas (e.g., Tao Hong Si Wu Tang, Dan Shen Yin, Hunag Lian Wen Dan Tang and Gua Lou Xie Bai Ban Xia Tang). In addition, these results delivered novel understandings of the molecular network mechanisms of IHD phenotype subtypes with PSCS complications, which would be both insightful for IHD precision medicine and the integration of disease and TCM syndrome diagnoses. PMID:29403392

Development of Simultaneous Analysis of Thirteen Bioactive Compounds in So-Cheong-Ryong-Tang Using UPLC-DAD

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Ji Hyun Jeong

2018-01-01

Full Text Available So-Cheong-Ryong-Tang, which is a standardized Korean medicine of the National Health Insurance, is a traditional prescription for the treatment of allergic rhinitis, bronchitis, and bronchial asthma. Simultaneous analysis and development of SCRT is essential for its stability, efficacy, and risk management. In this study, a simple, reliable, and accurate method using ultrahigh-performance liquid chromatography (UPLC fingerprinting with a diode array detector (DAD was developed for the simultaneous analysis. The chromatographic separation of the analytes was performed by an ACQUITY UPLC BEH C18 column (1.7 μM, 2.1 × 100 mm, Waters with a mobile phase of water containing 0.01% (v/v phosphoric acid and acetonitrile containing 0.01% (v/v phosphoric acid. The flow rate and detection wavelength were set at 0.4 mL/min and 215, 230, 254, and 280 nm. All calibration curves of the thirteen components showed good linearity (R2 > 0.999. The limit of detection and limit of quantification ranged 0.001–0.360 and 0.004–1.200 µg/mL, respectively. The relative standard deviation (RSD of intra- and interday was less than 2.60%, and the recoveries were within the range 76.08–103.79% with an RSD value of 0.03–1.50%. The results showed that the developed method was simple, reliable, accurate, sensitive, and precise for the quantification of bioactive components of SCRT.

Prevalence of value of work in human systems integration procedure Da prevalência do valor do trabalho humano na integração dos sistemas processuais

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Lourival José de Oliveira

2010-11-01

Full Text Available In today’s stage of development of Civil Procedure and the need to check the applicability of the constitutional guarantee of a reasonable duration of proceedings, the articles 769 and 889 of the Labor Code, which provides for the subsidiary application of the Common Law Procedure of Work, allow interpretation as the Federal Constitution and especially on the principles, providing the application of procedural rules more suited to the realization of the law. Therefore, this work intends to examine the scope of application as rules of procedure common to the labor process, especially concerning the recent innovations introduced by Law 11232/2005 and Law 11280/2006, limited to specific set of principles of Labor Law and the enhancement of human work. The approach is quite necessary, especially in dealing with ontological and axiological omissions, as well as eligibility and application of the Instrumentality, Speed, Effectiveness, Protection and Non-Social Regression Principles.Diante do atual estágio de desenvolvimento do Processo Civil e da necessidade de se conferir aplicação da garantia constitucional da duração razoável do processo, os artigos 769 e 889 da CLT que tratam sobre a aplicação subsidiária do Direito Comum ao Processo do Trabalho, comportam interpretação conforme a Constituição Federal e principalmente diante dos princípios, permitindo a aplicação de normas processuais mais adequadas à efetivação do Direito. Assim sendo, o presente trabalho analisa a aplicação subsidiária de normas do Processo Comum ao Processo do Trabalho, mormente no que tange as recentes inovações trazidas pelas Leis 11.232/2005 e 11.280/2006, tendo como parâmetro a principiologia específica do Direito do Trabalho, bem como a valorização do trabalho humano. A abordagem faz-se de extrema necessidade e valia, principalmente na análise de omissões ontológicas e axiológicas, bem como na admissibilidade e aplicação dos princ

Evaluation on the Pharmacological Effect of Traditional Chinese Medicine SiJunZiTang on Stress-Induced Peptic Ulcers

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Chiu-Mei Chen

2013-01-01

Full Text Available Purpose. To explore the effects of SiJunZiTang (SJZT on central neurotransmitters and the inhibition of HCl hypersecretion, along with the role of the vagus nerve. From this, the effects of SJZT and its constituent ingredients on inhibiting stress-induced peptic ulcers will be determined. Methods. Methods used to determine SJZT's effectiveness included (1 measuring the antipeptic ulcer effects of varying combinations of the constituents of SJZT; (2 evaluations of monoamine (MA level in the brain; and (3 measuring the effects of longer-term SJZT treatment. Results. Comparing the control and experimental groups where the rats’ vagus nerves were not cut after taking SJZT orally (500 mg/kg and 1000 mg/kg, the volume of enterogastric juice, free HCl and total acidity all reduce dose-dependently. The group administered SJZT at 1000 mg/kg showed significant reductions (P<0.05. For the experimental groups where the vagus nerves were cut, a comparison with the control group suggests that the group receiving SJZT (500 mg/kg orally for 21 days demonstrated a cure rate of 34.53%. Conclusion. The results display a correlation between the therapeutic effects of SJZT on stress-induced peptic ulcers and central neurotransmitter levels. Further to this, SJZT can inhibit the hypersecretion of HCl in the stomach, thus inhibiting stress-induced peptic ulcers.

Activity-dependent branching ratios in stocks, solar x-ray flux, and the Bak-Tang-Wiesenfeld sandpile model

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Martin, Elliot; Shreim, Amer; Paczuski, Maya

2010-01-01

We define an activity-dependent branching ratio that allows comparison of different time series Xt . The branching ratio bx is defined as bx=E[ξx/x] . The random variable ξx is the value of the next signal given that the previous one is equal to x , so ξx={Xt+1∣Xt=x} . If bx>1 , the process is on average supercritical when the signal is equal to x , while if bxmarket hypothesis.” For stock volumes, solar x-ray flux intensities, and the Bak-Tang-Wiesenfeld (BTW) sandpile model, bx is supercritical for small values of activity and subcritical for the largest ones, indicating a tendency to return to a typical value. For stock volumes this tendency has an approximate power-law behavior. For solar x-ray flux and the BTW model, there is a broad regime of activity where bx≃1 , which we interpret as an indicator of critical behavior. This is true despite different underlying probability distributions for Xt and for ξx . For the BTW model the distribution of ξx is Gaussian, for x sufficiently larger than 1, and its variance grows linearly with x . Hence, the activity in the BTW model obeys a central limit theorem when sampling over past histories. The broad region of activity where bx is close to one disappears once bulk dissipation is introduced in the BTW model—supporting our hypothesis that it is an indicator of criticality.

A utilização da teoria da aprendizagem significativa no ensino da Enfermagem

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Alana Tamar Oliveira de Sousa; Nilton Soares Formiga; Simone Helena dos Santos Oliveira; Marta Miriam Lopes Costa; Maria Júlia Guimarães Oliveira Soares

2015-01-01

RESUMO Objetivo: sintetizar a produção científica acerca da Teoria da Aprendizagem Significativa no processo de ensino-aprendizagem em Enfermagem. Método: revisão integrativa realizada nas bases de dados MEDLINE, LILACS, SciELO, BDENF e CINAHL, com artigos que abordaram a temática ou aspectos da teoria da aprendizagem significativa de David Ausubel. Fizeram parte da amostra dez artigos, sendo seis escritos no idioma português e quatro no inglês, publicados de 1998 a 2013. Resultados: cinco...

Publicidade e ética: um estudo da construção da imagem da mulher

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Elizabeth Moraes Gonçalves

2010-02-01

Full Text Available O texto propõe uma reflexão sobre a ética da responsabilidade na publicidade veiculada nas revistas Claudia e Nova. Trata-se de uma pesquisa descritiva, resultante da leitura dos anúncios selecionados, subsidiada por teóricos da Análise do Discurso da linha francesa, que busca averiguar como a mulher é representada. Constatou-se que no contexto da sociedade contemporânea o retrato da mulher como sedutora ainda está presente, mesmo que em vários momentos ela apareça como protagonista de sua própria vida.

A escolha da estrutura de capital sob fraca garantia legal: o caso do Brasil

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Ricardo D. Brito

2005-06-01

Full Text Available Este artigo mostra que as empresas de controle privado nacional se endividam mais que as de controle público ou estrangeiro, e o fazem pelo uso intensivo de dívida de curto prazo. A relação positiva entre ativos tangíveis e alavancagem de longo prazo confirma a previsão de trade-off. Divergindo das evidências brasileiras anteriores, o crescimento apresenta relação positiva com o endividamento, o que, conjuntamente com a relação negativa da rentabilidade, favorece a teoria de pecking order contra a de trade-off. Finalmente, e mais interessante, a maior sensibilidade do endividamento das empresas privadas nacionais aos fatores analisados parece indicar que os direitos do investidor externo à firma são menos resguardados pelo controlador privado nacional.This paper shows that the domestic controlled companies are more leveraged than the state controlled or than the foreign controlled ones, and that the formers make intensive use of short-term debt. The positive relation between tangible assets and long-term debt is consistent with the trade-off model's prediction. Different from previous evidences, investment opportunities are positively related to leverage, which combines with an inverse relation to profitability to favor the pecking order model against the trade-off model. Finally, and more interestingly, the higher sensitivity of domestic controlled firms' leverage to the analyzed factors seems to indicate that outsiders' rights are less protected by domestic insiders.

[Version and compilation of Harikyuuhousouyou of Vietnamese medical book].

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Du, Fengjuan; Xiao, Yongzhi

2018-02-12

Harikyuuhousouyou （《》）was written in 1827 and the author is unknown. The book has only one version which is collected by the National Library of Vietnam. The book contains one volume and includes contraindication of acupuncture and moxibustion, meridian points, point locations, indications and the therapeutic methods at extraordinary points. They are mainly cited from Zhen Jiu Da Quan (《》 Great Compendium on Acupuncture and Moxibustion ) by XU Feng , Yi Xue Ru Men (《》 Elementary Medicine ) by LI Chan and Shou Shi Bao Yuan (《》 Longevity and Health Preservation ) by GONG Tingxian in the Ming Dynasty. In the paper, in view of the characteristics of version and compilation, the hand-coped book was introduced. It was explored that Vietnam acupuncture absorbed Chinese medicine and emphasized clinical practice rather than theoretic statement.

Relationship between climate change and wars between nomadic and farming groups from the Western Han Dynasty to the Tang Dynasty period

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Su, Y.; Liu, L.; Fang, X. Q.; Ma, Y. N.

2015-07-01

In ancient China, the change in regional agriculture and animal husbandry productivity caused by climate change led to either wars or peaceful relations between nomadic and farming groups. From the Western Han Dynasty to the Tang Dynasty there were 367 wars between the two groups. The nomadic people initiated 69 % of the wars, but 62.4 % were won by the farmers. On a 30 year-period timescale, warm climates corresponded to a high incidence of wars. The conflicts between the nomadic and farming groups took place in some areas which are sensitive to climate change. During the cold periods, the battlefields were mostly in the southern regions. The main causes which leading to the above results are following: (1) warm climate provided a solid material foundation for nomadic and farming groups, especially contributed to improve the productivity of nomadic group; meanwhile, the excessive desire for essential means of subsistence in nomadic group could led to wars. (2) During the cold periods, people of farming group moved to the south and construct the south, meanwhile, nomadic group occupied the central plains, thus the battlefields also changed. As the background, climate change plays an indirect role in wars between groups.

Production extensive de jeunes saumons atlantiques (Salmo salar L. d'un an dans l'étang du Boucheron (Corrèze

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DUMAS J.

1981-07-01

Full Text Available Dans le cadre du plan de restauration du Saumon dans la Dordogne, un élevage extensif de tacons de repeuplement est expérimenté dans un étang de pénéplaine où des alevins de saumons ont été immergés. Pour une première année d'élevage, cette pièce d'eau a procuré 2 150 jeunes saumons d'un an d'une grande taille moyenne (13,1 cm pour 21,2 g. La proportion de saumoneaux (smolts y est très importante (80,3 %. La survie depuis la mise en charge est élevée (14,3 % comparée à celle observée dans les rivières à saumons. La densité du peuplement à la récolte est, par hectare, de 879 juvéniles pour un poids de 18,6 kg. Les nombreux plans d'eau sur le haut bassin de la Dordogne peuvent constituer à peu de frais un outil de production de jeunes saumons pour le repeuplement de cette rivière.

Arquitetura da paisagem da cidade e a importância da sistematização da análise do problema projetual

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Rodrigo Gonçalves dos Santos

2007-12-01

Full Text Available Com este artigo pretende-se levantar os conceitos próprios da atividade da Arquitetura Paisagística encarando-a como disciplina projetual e associando-a ao Design Ambiental, necessitando, assim, de linhas metodológicas específicas para apresentação de soluções coerentes aos problemas paisagísticos. Sob esta ótica, reflexões sobre o uso da vegetação no projeto dos espaços exteriores são apresentadas apontando-se uma etapa de sistematização da análise do problema de projeto, dentro da abordagem da concepção de uma metodologia projetual em arquitetura paisagística. Também foram analisadas oito vias de circulação da área central de Florianópolis, Santa Catarina, Brasil, exemplificando uma etapa de sistematização da análise do problema de projeto.

[Nomenclature of Feiyang (BL 58) and its connotation exploration based on A-B Classic of Acupuncture and Moxibustion].

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Feng, Shuangshuang; Hou, Zhongwei

2018-04-12

A - B Classic of Acupuncture and Moxibustion ( Zhen Jiu Jia Yi Jing ) is the earliest and existed well-known work on acupuncture and moxibustion, with irreplaceable literature values and huge impacts on the later generations. Feiyang (BL 58) is the luo -connecting point of the bladder meridian and recorded 11 times in A - B Classic of Acupuncture and Moxibustion . This book is the representative for the exploration on the acupoint nomenclature and clinical connotation. Through the investigation on the textual connotation of the specified terms and the alias of Feiyang (BL 58), it was discovered that the nomenclature of this acupoint was based on the main symptoms, the characters of the running course of meridian and acupuncture effects. It was proved that the unique property of this acupoint was as rising, dispersing and flying of meridian qi . In comparison of Huangdi Three - Version of A - B Classic of Acupuncture and Moxibustion ( Huangdi Sanbu Zhen Jiu Jia Yi Jing ) of the printed edition of the Song Dynasty version and Meridian - Collateral and Acupoints ( Zhen Jiu Shu Xue Xue ), it was found that the indications and connotation of Feiyang (BL 58) were more extensively richer than the records in teaching materials. Those study results contribute to the extension of the clinical application of this acupoint.

Para além da paz liberal? respostas ao "retrocesso" Beyond liberal peace? responses to "backsliding"

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Oliver P Richmond

2010-12-01

Full Text Available A ortodoxia familiar de construção da paz liberal depende da transplantação e da exportação de condicionalidade e dependência, com vistas a consolidar um contrato social entre populações, seus governos e o Estado, em que repouse uma paz liberal legítima e consensual. O que, com frequência, ocorre, é uma forma híbrida de paz liberal, sujeita a críticas locais poderosas, à resistência, por vezes, e à percepção de que a construção da paz internacional está fracassando em corresponder às expectativas. Em termos kantianos, os problemas com que a paz liberal tem se deparado e a crise pela qual está hoje passando podem ser denominados "retrocesso". Tem sido particularmente notável que a construção da paz liberal não vem sendo capaz de construir políticas unidas a partir de fragmentos territoriais no Kosovo, na Bósnia, no Afeganistão, no Iraque, no Sri Lanka e mesmo na Irlanda do Norte, onde alguns ou todos de seus elementos estão em desenvolvimento. Isso indica uma necessidade ou de reforma do modelo liberal para a paz, ou de estabelecimento de uma capacidade de coexistência desse modelo com alternativas, ou de substituição do modelo. Este artigo examina uma gama de questões inerentes ao paradigma de construção da paz liberal, algumas causas de "retrocesso" e o que pode ser feito no que tange a tais causas, no sentido de utilizar a construção da paz para criar um novo contrato social e atingir o que se poderia muito bem ser uma forma "híbrida liberal-local" de paz.The familiar orthodoxy of liberal peacebuilding depends upon transplanting and exporting conditionality and dependency in order to cement a social contract between populations, their governments and the state, on which rests a legitimate and consensual liberal peace. What often emerges is a hybrid form of the liberal peace, subject to powerful local critiques, sometimes resistance, and to the perception that international peacebuilding is failing to

Simultaneous determination of thirteen flavonoids from Xiaobuxin-Tang extract using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.

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Cen, Meifeng; Ruan, Jinxiu; Huang, Lihua; Zhang, Zhenqing; Yu, Nengjiang; Zhang, Youzhi; Cheng, Xuange; Xiong, Xiaohong; Wang, Guixiang; Zang, Linquan; Wang, Sujun

2015-11-10

A simple and reliable high performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS) analysis method was established to simultaneously determine thirteen flavonoids of Xiaobuxing-Tang in intestine perfusate, namely onpordin, 3'-O-methylorobol, glycitein, patuletin, genistein, luteolin, quercetin, nepitrin, quercimeritrin, daidzin, patulitrin, quercetagitrin and 3-glucosylisorhamnetin. Detection was performed on a quadrupole mass spectrometer equipped with an electrospray ionization (ESI) source operating in negative ionization mode. Negative ion ESI was used to form deprotonated molecules at m/z 315 for onpordin, m/z 299 for 3'-O-methylorobol, m/z 283 for glycitein, m/z 331 for patuletin, m/z 269 for genistein, m/z 285 for luteolin, m/z 301 for quercetin, m/z 477 for nepitrin, m/z 463 for quercimeritrin, m/z 461 for daidzin, m/z 493 for patulitrin, m/z 479 for quercetagitrin, m/z 477 for 3-glucosylisorhamnetin and m/z 609.2 for rutin. The linearity, sensitivity, selectivity, repeatability, accuracy, precision, recovery and matrix effect of the assay were evaluated. The proposed method was successfully applied to simultaneous determination of these thirteen flavonoids, and using this method, the intestinal absorption profiles of thirteen flavonoids were preliminarily predicted. Copyright © 2015 Elsevier B.V. All rights reserved.

Mitologia afro-baiana: possibilidade de uma prática pedagógica

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Nilson Carvalho Crusoé Júnior

2016-07-01

Full Text Available Trata-se de um trabalho no qual elenca-se elementos contextuais que podem servir de ferramentas para que professores possam trabalhar com novas abordagens pedagógicas e perspectivas ideológicas distintas das tradicionais. Aponta a valorização do papel simbólico e estético da mitologia em geral, como sendo de importância cabal para a formação de educandos críticos e sensíveis às transformações sociais, no que tange à formação das culturas brasileira e baiana, em especial. Nesses contornos, perceber que o entendimento da mitologia afro-brasileira é essencial, pois formula e instiga vivências históricas daqueles que são herdeiros diretos dos grupos menos favorecidos da nossa sociedade.

Study on energy efficiency in Vietnamese row house - case study of Tang Nhon Phu A Ward, District 9, HCMC

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Thao, H. T. P.; Nam, N. D.

2018-04-01

District 9 is a new urban development area which is well-known as an industrial city in the rear of Ho Chi Minh City. This area has special characteristics which are different from central downtown. The housing of district 9 is a new urban area so that it is easier to orient particular architectural style accordance with climatic conditions and other conditions. However, at present, these new residential areas are rising with no clear management of architectural form. That is the reason lead to shortcomings such as: increasing the use of electricity, affecting to climate change and creating urban heat island, increasing costs of energy use. Those problems will be difficult to overcome in the future if we don’t have the right attention on it. By using a combination of multiple methods such as: data collection, case study analysis method, GIS, research by design, etc., this research topic will pay attention on analysis the row house in Tang Nhon Phu A Ward of district 9 and trying to propose some solution and management criteria to local government. The analysis results will ensure that the conclusions reflect the realities of the situation, those also become the basis for the proposed solutions to deal with the existence problems. The result of research may become an application research platform for the related research topics.

Si-Wu-tang extract stimulates bone formation through PI3K/Akt/NF-κB signaling pathways in osteoblasts.

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Wu, Chi-Ming; Chen, Po-Chun; Li, Te-Mao; Fong, Yi-Chin; Tang, Chih-Hsin

2013-10-24

Si-Wu-Tang (SWT), a Traditional Chinese Medicine (TCM) formula, is widely used for the treatment of gynopathies diseases such as menstrual discomfort, climacteric syndrome, dysmenorrhea, and other estrogen-related diseases. Recent studies have shown that SWT can treat primary dysmenorrhea, have anti-pruritic anti-inflammatory effects, and protect against radiation-induced bone marrow damage in an animal model. It has been reported that anti-inflammatory and anti-oxidant agents have the potential to treat osteoporosis by increasing bone formation and/or suppressing bone resorption. However, the effect of SWT on bone cell function has not yet been reported. Alkaline phosphatase (ALP), bone morphogenetic proteins (BMP)-2, and osteopontin (OPN) mRNA expression was analyzed by qPCR. The mechanism of action of SWT extract was investigated using western blotting. The in vivo anti-osteoporotic effect of SWT extract was assessed in ovariectomized mice. Here, we report that SWT increases ALP, BMP-2, and OPN expression as well as bone mineralization. In addition, we show that the PI3K, Akt, and NF-κB signaling pathways may be involved in the SWT-mediated increase in gene expression and bone mineralization. Notably, treatment of mice with SWT extract prevented bone loss induced by ovariectomy in vivo. SWT may be used to stimulate bone formation for the treatment of osteoporosis.

Compositions, Formation Mechanism, and Neuroprotective Effect of Compound Precipitation from the Traditional Chinese Prescription Huang-Lian-Jie-Du-Tang

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Chenze Zhang

2016-08-01

Full Text Available Compounds in the form of precipitation (CFP are universally formed during the decocting of Chinese prescriptions, such as Huang-Lian-Jie-Du-Tang (HLJDT. The formation rate of HLJDT CFP even reached 2.63% ± 0.20%. The identification by liquid chromatography mass spectrometry (LC-MSn proved that the main chemical substances of HLJDT CFP are baicalin and berberine, which is coincident with the theory that the CFP might derive from interaction between acidic and basic compounds. To investigate the formation mechanism of HLJDT CFP, baicalin and berberine were selected to synthesize a simulated precipitation and then the baicalin–berberine complex was obtained. Results indicated that the melting point of the complex interposed between baicalin and berberine, and the UV absorption, was different from the mother material. In addition, 1H-NMR integral and high-resolution mass spectroscopy (HR-MS can validate that the binding ratio was 1:1. Compared with baicalin, the chemical shifts of H and C on glucuronide had undergone significant changes by 1H-, 13C-NMR, which proved that electron transfer occurred between the carboxylic proton and the lone pair of electrons on the N atom. Both HLJDT CFP and the baicalin–berberine complex showed protective effects against cobalt chloride-induced neurotoxicity in differentiated PC12 cells. It is a novel idea, studying the material foundation of CFP in Chinese prescriptions.

A utilização da teoria da aprendizagem significativa no ensino da Enfermagem

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Alana Tamar Oliveira de Sousa

2015-08-01

Full Text Available RESUMOObjetivo:sintetizar a produção científica acerca da Teoria da Aprendizagem Significativa no processo de ensino-aprendizagem em Enfermagem.Método:revisão integrativa realizada nas bases de dados MEDLINE, LILACS, SciELO, BDENF e CINAHL, com artigos que abordaram a temática ou aspectos da teoria da aprendizagem significativa de David Ausubel. Fizeram parte da amostra dez artigos, sendo seis escritos no idioma português e quatro no inglês, publicados de 1998 a 2013.Resultados:cinco artigos fizeram alusão à Teoria da Aprendizagem Significativa, quatro citaram Ausubel como autor dessa teoria e apenas dois seguiram a estrutura para a aplicação da teoria completamente. Há escassez de estudos sobre o tema e os que o abordam não o correlacionam com a teoria de Ausubel.Conclusão:faz-se necessário romper com a dicotomia entre teoria e prática e promover a articulação dos conteúdos com a ação, introduzindo o aluno como autor de seu próprio conhecimento.

Atualizações do diálogo entre a teoria QUEER e a educação

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Ricardo Maria dos Santos

2012-05-01

Full Text Available Este trabalho pretende atualizar algumas contribuições que a teoria queer vem apresentando nas discussões sobre as identidades sexuais no âmbito educacional, através da exposição de como as teorias pós-identitárias em geral e a teoria queer em particular possibilitam a avaliação de diferentes aspectos a serem levados em conta na discussão da diversidade sexual em instituições escolares. Baseando-se em obras publicadas recentemente no Brasil e no exterior, além da prática docente do autor, esta pesquisa também relata pequenas, mas significativas alterações no comportamento de alunos de ensino superior quanto à expressão de suas sexualidades, especificamente no que tange à verbalização de experiências que se situam fora da heteronormatividade.

Activity-dependent branching ratios in stocks, solar x-ray flux, and the Bak-Tang-Wiesenfeld sandpile model.

Science.gov (United States)

Martin, Elliot; Shreim, Amer; Paczuski, Maya

2010-01-01

We define an activity-dependent branching ratio that allows comparison of different time series X(t). The branching ratio b(x) is defined as b(x)=E[xi(x)/x]. The random variable xi(x) is the value of the next signal given that the previous one is equal to x, so xi(x)=[X(t+1) | X(t)=x]. If b(x)>1, the process is on average supercritical when the signal is equal to x, while if b(x)efficient market hypothesis." For stock volumes, solar x-ray flux intensities, and the Bak-Tang-Wiesenfeld (BTW) sandpile model, b(x) is supercritical for small values of activity and subcritical for the largest ones, indicating a tendency to return to a typical value. For stock volumes this tendency has an approximate power-law behavior. For solar x-ray flux and the BTW model, there is a broad regime of activity where b(x) approximately equal 1, which we interpret as an indicator of critical behavior. This is true despite different underlying probability distributions for X(t) and for xi(x). For the BTW model the distribution of xi(x) is Gaussian, for x sufficiently larger than 1, and its variance grows linearly with x. Hence, the activity in the BTW model obeys a central limit theorem when sampling over past histories. The broad region of activity where b(x) is close to one disappears once bulk dissipation is introduced in the BTW model-supporting our hypothesis that it is an indicator of criticality.

Electronic structure and charge transport in nonstoichiometric tantalum oxide

Science.gov (United States)

Perevalov, T. V.; Gritsenko, V. A.; Gismatulin, A. A.; Voronkovskii, V. A.; Gerasimova, A. K.; Aliev, V. Sh; Prosvirin, I. A.

2018-06-01

The atomic and electronic structure of nonstoichiometric oxygen-deficient tantalum oxide TaO x<2.5 grown by ion beam sputtering deposition was studied. The TaO x film content was analyzed by x-ray photoelectron spectroscopy and by quantum-chemistry simulation. TaO x is composed of Ta2O5, metallic tantalum clusters and tantalum suboxides. A method for evaluating the stoichiometry parameter of TaO x from the comparison of experimental and theoretical photoelectron valence band spectra is proposed. The charge transport properties of TaO x were experimentally studied and the transport mechanism was quantitatively analyzed with four theoretical dielectric conductivity models. It was found that the charge transport in almost stoichiometric and nonstoichiometric tantalum oxide can be consistently described by the phonon-assisted tunneling between traps.

ANALYSIS OF REMOTE SENSING ARCHAEOLOGY ON TRAFFIC FUNCTION TRANSFORMATION OF TONGJI GRAND CANAL IN SUI AND TANG DYNASTIES

Institute of Scientific and Technical Information of China (English)

WANG Xin-yuan; HE Hui; ZHOU Ying-qiu; GAO Chao; HAN Shuang-wang

2006-01-01

In China, most directions of river flowing are from west to east. During historic period, since the water traffic played an important role, it was very important to form a cross-horizontal net of water carriage route. Canals should be dug so as to make up the lack of north-south river. Tongji Grand Canal, dug in the first year of Daye (605 A.D.) in the Sui Dynasty, was the important component of north-south system of Grand Canals in China. It promoted economic and social development of the Sui, Tang and Song dynasties (605 A.D.-1279 A.D.). As Tongji Canal (i.e.Tongji Grand Canal) flowed across the Huaibei Plain, which is aggraded by abundant mud and sand deposit resulted from the Huanghe (Yellow) River flooding, many traces (such as old channel) and human culture heritages were buried under mud-sand. Tongji Canal was silted up, and disappeared in the Jin Dynasty (1115 A.D.-1234 A.D.). From then on, there were many different stories about the flowing route of the canal in historical literature. Based on space-bone and air-bone remote sensing imagery, we attempt to search the old channel of Tongji Canal, and supplement historical record. The paper discusses transformation process of Tongji Canal's traffic function, and resumptively summarizes the reasons of the transformation, which results from synthetic function of physical geographical, political, economic, and social conditions.

Gestões do desenvolvimento e desenvolvimentos da gestão: da unilateralidade reificada à dialogicidade da simbiose homem/natureza

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Carlos Eduardo Justen

Full Text Available Este artigo, ao situar culturalmente os fenômenos da gestão e do desenvolvimento, em sua concepção tradicional, no projeto da modernidade e ao identificar o predomínio da unilateralidade reificada na interface entre gestão e desenvolvimento - a primeira vista como instrumento técnico submisso à via clássica do segundo - almeja evidenciar as potencialidades da compreensão e da construção de alternativas, tanto para a gestão como para o desenvolvimento, a partir da ressignificação dessa interface. Para tanto, o esforço foi direcionado ao resgate do que é comum aos fenômenos da gestão e do desenvolvimento - os substratos antropológico e ecológico -, nucleados nos princípios da reciprocidade dialógica, concretizadora da condição antropológica, e da finitude, caracterizadora da condição ecológica. Ao final, são apresentadas oito potenciais contribuições advindas da exploração renovada da interface entre a gestão e o desenvolvimento. Propôs-se, ainda, a substituição da lógica instrumental da eficiência financeira, comum à concepção tradicional dos fenômenos estudados, pela lógica da simbiose dialógica homem/natureza, uma vez que, como fenômenos sociais, desenvolvimento e gestão, mediados pelo meio, também são ecológicos em sua essência.

Role of exact exchange in thermally-assisted-occupation density functional theory: A proposal of new hybrid schemes.

Science.gov (United States)

Chai, Jeng-Da

2017-01-28

We propose hybrid schemes incorporating exact exchange into thermally assisted-occupation-density functional theory (TAO-DFT) [J.-D. Chai, J. Chem. Phys. 136, 154104 (2012)] for an improved description of nonlocal exchange effects. With a few simple modifications, global and range-separated hybrid functionals in Kohn-Sham density functional theory (KS-DFT) can be combined seamlessly with TAO-DFT. In comparison with global hybrid functionals in KS-DFT, the resulting global hybrid functionals in TAO-DFT yield promising performance for systems with strong static correlation effects (e.g., the dissociation of H 2 and N 2 , twisted ethylene, and electronic properties of linear acenes), while maintaining similar performance for systems without strong static correlation effects. Besides, a reasonably accurate description of noncovalent interactions can be efficiently achieved through the inclusion of dispersion corrections in hybrid TAO-DFT. Relative to semilocal density functionals in TAO-DFT, global hybrid functionals in TAO-DFT are generally superior in performance for a wide range of applications, such as thermochemistry, kinetics, reaction energies, and optimized geometries.

Preparation of p-type transparent conducting tin-antimony oxide thin films by DC reactive magnetron sputtering

Energy Technology Data Exchange (ETDEWEB)

Ji, Zhenguo [College of Electronic Information, Hangzhou Dianzi University, Hangzhou (China); State Key Laboratory for Silicon Materials, Zhejiang University, Hangzhou (China); Xi, Junhua; Huo, Lijuan; Zhao, Yi [State Key Laboratory for Silicon Materials, Zhejiang University, Hangzhou (China)

2008-07-01

P-type transparent conducting tin-antimony oxide (TAO) films were successfully prepared by DC reactive magnetron sputtering followed by post annealing in the air. Structural, optical and electrical properties of the TAO films were investigated. X-ray diffraction studies showed that the films are polycrystalline with orthorhombic structure of Sb{sub 2}O{sub 4}. UV-Visible absorption and transmittance spectra showed that the optical band-gap of the TAO films is about 3.90 eV, and the overall transmittance is higher than 85% in the visible region. Hall effect measurement indicated that the Sn/Sb ratio is a critical parameter to get p-type conducting TAO films. It was found that 0.19TAO films could be obtained. Hole concentration as high as 4.03 x 10{sup 19} cm{sup -3} and electrical resistivity as low as 0.155 {omega}cm were achieved, showing potential applications of TAO films as p-type transparent conducting films. (copyright 2008 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Cooperação Econômica Internacional: estudo de Caso da Petrobrás - Perspectivas e Análise dos Riscos Assumidos nos Investimentos do Brasil na Bolívia - 10.5102/uri.v4i2.230

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Elaine Barbosa Santana

2007-10-01

Full Text Available Os elementos conceituais da cooperação econômica são elencados no presente estudo, mostrando a relação política bilateral assignada entre Brasil e Bolívia, especialmente no que tange ao gás bolivianos e a atuação de Petrobrás. O conceito de soberania é colocado sob júdice no âmbito do acordo de cooperação firmado com a Bolívia, e a alegação da necessidade de privatização do gás, em virtude de novos parâmetros governamentais sob o Governo de Evo Morales, e as pressões dos movimentos indígenas. As questões jurídicas e econômicas imbricadas na órbita da cooperação e integração são analisadas, mesmo que a opinião pública e a mídia se voltem contra os dispositivos legais. Nesse contexto, compreende-se que os acordos internacionais sobre as políticas comerciais são processos de cooperação econômica e não de integração como alguns estudiosos apregoam. Pode até ser considerado como uma abertura que favoreça a integração, mas não há supressão de qualquer barreira discriminatória. No caso do Brasil com a Bolívia, ocorreu um processo de cooperação econômica internacional, visto que se trata de acordo que prevê benefícios mútuos e não prevê qualquer uma das fases da integração econômica. O recorte do presente manuscrito abrange o direito processual no que se refere aos mecanismos para a concretização da cooperação jurídica no âmbito da organização judiciária, forma de operacionalização, eficácia dos dispositivos que regulam o procedimento e interpretação atribuída a normas relacionadas à temática.

Concentration-dependent effects of fullerenol on cultured hippocampal neuron viability

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Zha YY

2012-06-01

Full Text Available Ying-ying Zha,1 Bo Yang,1 Ming-liang Tang,2 Qiu-chen Guo,1 Ju-tao Chen,1 Long-ping Wen,3 Ming Wang11CAS Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, 2Suzhou Institute of NanoTech and NanoBionics, Chinese Academy of Sciences, Suzhou, 3Laboratory of Nano-biology, School of Life Sciences, University of Science and Technology of China, Hefei, People's Republic of ChinaBackground: Recent studies have shown that the biological actions and toxicity of the water-soluble compound, polyhydroxyfullerene (fullerenol, are related to the concentrations present at a particular site of action. This study investigated the effects of different concentrations of fullerenol on cultured rat hippocampal neurons.Methods and results: Fullerenol at low concentrations significantly enhanced hippocampal neuron viability as tested by MTT assay and Hoechst 33342/propidium iodide double stain detection. At high concentrations, fullerenol induced apoptosis confirmed by Comet assay and assessment of caspase proteins.Conclusion: These findings suggest that fullerenol promotes cell death and protects against cell damage, depending on the concentration present. The concentration-dependent effects of fullerenol were mainly due to its influence on the reduction-oxidation pathway.Keywords: fullerenol, nanomaterial, neurotoxicity, neuroprotection, hippocampal neuron

O sentido da espiritualidade na transitoriedade da vida

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Isabel Cristina de Oliveira Arrieira

Full Text Available Resumo Objetivo: Compreender o sentido da espiritualidade para a pessoa em cuidados paliativos. Métodos: Abordagem qualitativa, fundamentada na fenomenologia existencialista e referencial de Viktor Frankl. Os participantes foram nove pessoas em cuidados paliativos atendidas no domicílio. Informações coletadas por meio da observação e de entrevista realizadas no período de junho a outubro de 2014, gravadas, transcritas e transformadas em texto interpretado com a abordagem fenomenológica hermenêutica. Resultados: Surgiram as seguintes categorias: sentido de continuidade da vida; sentido de alívio do sofrimento; sentido de naturalidade da morte e sentido de valorização do viver. Conclusão: Para a integralidade da atenção faz-se necessário a inclusão da espiritualidade na prática do cuidado em saúde. A espiritualidade proporciona o encontro existencial entre a pessoa em cuidados paliativos e os profissionais que a cuidam em sua integralidade.

A NECESSIDADE DE PROTEÇÃO LEGAL HOMOAFETIVA: O PLC N. 122/2006 A necessidade de proteção legal homoafetiva: o PLC n.122/2006

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Gabriela Soares Balestero

2010-12-01

Full Text Available

O presente estudo trata da necessidade de dar proteção legal às minorias sexuais no que tange a criminalização de práticas discriminatórias. Na Constituinte de 1988, ao proibir discriminação de qualquer tipo, o Congresso legalizou "ser" homossexual. Desde então, contudo, pouca coisa se fez no Legislativo para combater o preconceito com base na orientação sexual. Em sua atividade, os congressistas continuam a desconsiderar as conseqüências práticas da vivência plena da homossexualidade, sendo que tal fato pode ser observado diante da inércia na aprovação do Projeto de Lei n. 122 que visa a criminalização da homofobia. Ser hétero ou homossexual não deveria acarretar qualquer diferença em termos de tratamento pelo Estado, pois sem dúvida deve haver o respeito aos princípios constitucionais de igualdade, da dignidade da pessoa humana, aliados aos demais valores fundamentais, e princípios gerais que regem o direito brasileiro.

O presente estudo trata da necessidade de dar proteção legal às minorias sexuais no que tange a criminalização de práticas discriminatórias. Na Constituinte de 1988, ao proibir discriminação de qualquer tipo, o Congresso legalizou "ser" homossexual. Desde então, contudo, pouca coisa se fez no Legislativo para combater o preconceito com base na orientação sexual. Em sua atividade, os congressistas continuam a desconsiderar as conseqüências práticas da vivência plena da homossexualidade, sendo que tal fato pode ser observado diante da inércia na aprovação do Projeto de Lei n. 122 que visa a criminalização da homofobia. Ser hétero ou homossexual não deveria acarretar qualquer diferença em

Taoism and Its Implications for Science Education.

Science.gov (United States)

Hua, Hsiao-Peng; Chang, Chun-Yen; MacRaven, Maggie Maeve

As one of the major schools of thought in ancient China, Taoism centers on the concept of "Tao", the Way, which has two distinct characteristics: (1) Tao itself can be deemed as a final "reality" that is equivalent to the ontology of the Universe; and (2) Tao itself cannot be defined directly by human language. Taoism posits a holistically…

Paradigmas e tendências do ensino universitário: a metodologia da pesquisa-ação como estratégia de formação docente

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Erica Toledo de Mendonça

2015-06-01

Full Text Available O objetivo do trabalho foi discutir sobre os paradigmas e as tendências do ensino universitário na atualidade, apontando estratégias de formação docente. Utilizou-se como método a pesquisa-ação; os dados foram coletados mediante as técnicas do Panorama Sobe e Desce, Wordle e Diários de Classe, durante a realização de capacitações docentes para exercício de tutoria em disciplina semipresencial. Os depoimentos dos participantes apontaram para uma insatisfação no uso do modelo tradicional de ensino; a importância de o professor estar aberto ao novo; e, ainda, que a utilização de processos inovadores de ensinagem foi considerada importante estratégia de mudança de paradigma educacional. O processo de capacitação de docentes universitários mostrou-se eficaz no que tange à conscientização destes indivíduos quanto à importância de se inserir o ensino na agenda das prioridades da universidade.

Hierarquização da eficiência de remoção de cianotoxinas por meio de adsorção em carvão ativado granular

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Maria Natália Costa e Silva

2017-08-01

Full Text Available RESUMO O trabalho objetivou avaliar a remoção concomitante de duas cianotoxinas - microcistina-LR e saxitoxina-STX - por meio da adsorção em carvão ativado granular. Em primeira etapa, três carvões de granulometrias distintas, dois de coco de dendê e um mineral, foram avaliados na adsorção de microcistina-LR em água destilada e tratada com concentrações de 3,9 a 9,4 ug.L-1. O carvão de coco de dendê de menor granulometria apresentou desempenho mais uniforme, tanto no que tange à remoção (% de microcistina-LR, quanto ao volume de efluente produzido consoante com as recomendações do padrão de potabilidade brasileiro. Em segunda etapa, apenas para o carvão selecionado na etapa precedente, concentrações de microcistina-LR e saxitoxina-STX aproximadamente 50% superiores dos limites do mesmo padrão de potabilidade foram dispersas em água destilada. Tais ensaios de adsorção evidenciaram que apenas a adsorção de saxitonina não foi influenciada pela simultaneidade das duas cianotoxinas.

Processos da construção da Política Nacional de Promoção da Saúde

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João Leite Ferreira Neto

2013-10-01

Full Text Available Investigou-se os processos de construção da Política Nacional de Promoção da Saúde (PNPS, pela análise de três documentos produzidos pelo Ministério da Saúde entre 2002 e 2005 e do texto final da PNPS. Foram entrevistados cinco sujeitos que participaram da construção da PNPS, dos quais três eram gestores do Ministério da Saúde e dois pesquisadores. Os documentos foram explorados com a Análise do Discurso. O artigo contribui para aprofundar os debates sobre o processo de construção da PNPS. A promoção da saúde revelou seus antagonismos, o que motivou a demora de sua aprovação final. A indução internacional via financiamento demonstrou ser o elemento crucial para a definição da forma final da PNPS, trazendo de volta a criticada ênfase na mudança de estilos de vida em suas "Ações". Destaca-se o processo de produção negociada de consenso, que culminou com a criação do Comitê Gestor da PNPS, com a participação de diversos subsetores, estrutura inovadora no Ministério da Saúde.

Semantics-based Automated Web Testing

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Hai-Feng Guo

2015-08-01

Full Text Available We present TAO, a software testing tool performing automated test and oracle generation based on a semantic approach. TAO entangles grammar-based test generation with automated semantics evaluation using a denotational semantics framework. We show how TAO can be incorporated with the Selenium automation tool for automated web testing, and how TAO can be further extended to support automated delta debugging, where a failing web test script can be systematically reduced based on grammar-directed strategies. A real-life parking website is adopted throughout the paper to demonstrate the effectivity of our semantics-based web testing approach.

O DEBATE CHOMSKY-PIAGET REVISITADO: UM ESTUDO A FAVOR DA ESTRUTURA RELATIVA COMO UMA ESTRATÉGIA COGNITIVA NA SLA

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Gislaine Machado Jerônimo

2011-01-01

Full Text Available Resumo: O presente trabalho lida com o conceito de relativização, o qual trata da aquisição de estruturas complexas - orações relativas restritivas por aprendizes brasileiros de Inglês como língua estrangeira (LE. A estrutura relativa foi escolhida porque é considerada uma das estruturas mais importantes usada nas línguas de todo mundo por ter o recurso de encaixamento, podendo variar consideravelmente em termos de sua distribuição e forma sintática. O principal objetivo é diagnosticar estratégias, empregadas pelos aprendizes já mencionados, para a resolução de determinadas tarefas, aqui chamadas de desafios. Tais desafios convidam ao uso de estruturas que alternam em sujeito-sujeito (SS, sujeito-objeto (SO, objeto-sujeito (OS e objeto-objeto (OO. Estas estruturas são caracterizadas por uma diversidade sintática que ocorre de acordo com a posição dos personagens dos desafios (come- come. Como alternativa para relativização, os sujeitos das atividades (aprendizes de Inglês utilizaram estratégias como apassivação de uma das orações, uso de orações adverbiais, emprego de orações coordenadas aditivas e de duas orações independentes. Anterior a coleta de dados foi aplicado um pré-teste com professores graduados de Língua Inglesa e com alunos do nível pós-avançado de um curso de Inglês, para validar o instrumento. Os sujeitos da pesquisa foram alunos de 3°ano do Ensino Médio entre 15 e 17 anos de idade. Aspectos como idade e experiência no exterior foram levados em consideração. Dentre as estratégias, a estrutura aditiva foi a mais utilizada, seguida da relativização. Os resultados mostraram que estes aprendizes fizeram uso do seu conhecimento cognitivo para desenvolver formas alternativas no que tange à resolução de cada desafio. O referencial teórico foi baseado, principalmente, em AXT (1994.

A Gastronomia e o Turismo

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Rosana Peccini

2013-06-01

Full Text Available A finalidade deste artigo é a de contribuir para o entendimento de alguns conceitos sobre gastronomia e alimentação, aprofundando a reflexão sobre o Turismo Gastronômico. Além dos conceitos, procura-se discutir e ampliar as múltiplas possibilidades para se pensar a alimentação, no que tange suas relações com a atividade turística. A análise que se propõe neste artigo é de caráter multidisciplinar, feita a través da interpretação de diversos autores, que pensam sobre a comida como uma expressão da identidade de determinado grupo social.

HOMO ACADEMICUS: CRISE IDENTITÁRIA E PRÁTICA CIENTÍFICA

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Dina Maria Martins Ferreira

2012-12-01

Full Text Available Este estudo visa a argumentar sobre o construto identitário do homo academicus, ou seja, o intelectual que se estabelece no campo universitário, compartilha habitus e atitude dóxica (Bourdieu, 2007; 2009; 2011. No que tange às etiquetas identificadoras,  Bauman  (2007 categoriza o intelectual pela prática científica, situada por relações históricas. Na convergência entre espaço, valores e performativos, constrói-se uma estrada da qual emergem a  prática logocêntrica que se transforma em dogma a partir da permanência de práticas dóxicas do século das Luzes. 

Teoria da adequação econômica da conduta: significado econômico da conduta em face da tutela penal antitruste

OpenAIRE

Luiz da Silva, Ivan

2009-01-01

Essa tese tem por objetivo o desenvolvimento da teoria da adequação econômica da conduta no direito penal econômico. Vale-se de uma abordagem interdisciplinar abrangendo a Economia, o direito econômico e o direito penal. Para alcançar o desiderato a investigação analisou a intervenção do direito penal em face da atividade econômica e, em especial, os fundamentos da tutela penal antitruste, para fins de estabelecer os contornos teóricos necessários à aplicação das premissas fund...

PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy

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Pei Mou

2018-01-01

Full Text Available Background. Thyroid associated ophthalmopathy (TAO is an autoimmune disease, which involves inflammation and tissue remodeling. Pentraxin-3 (PTX3 is a component of innate immune system and recently implicated in autoimmunity. This observation may indicate that PTX3 participates in the inflammatory process of TAO. Methods. All studies were performed on TAO patients and healthy controls (45: 28 in total. RNA-seq was used to detect differential gene expression of orbital adipose-connective tissue. Quantitative PCR was performed to verify the results. PTX3 protein in orbital adipose-connective tissues was visualized by immunohistochemistry (IHC. PTX3 concentration in serum was determined by enzyme-linked immunosorbent assay (ELISA. Results. RNA-seq showed 1.86-log⁡2FC higher PTX3 expression in the orbital adipose-connective tissues from TAO group than controls (FDR = 0.0059. qPCR confirmed the difference (5.59-fold increase, p=0.0012. The presence of PTX3 protein was demonstrated. Orbital adipose tissue from healthy controls showed weak staining for PTX3 while tissue from TAO group was strongly positive. Serum PTX3 concentration was significantly elevated in patients when compared to the control group (1.9-fold increase; p<0.0001. Conclusions. Patients with TAO showed increased presence of PTX3 in orbital tissue and serum, which may suggest a potential relationship of PTX3 and TAO.

PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy

Science.gov (United States)

Chen, Ziyu

2018-01-01

Background Thyroid associated ophthalmopathy (TAO) is an autoimmune disease, which involves inflammation and tissue remodeling. Pentraxin-3 (PTX3) is a component of innate immune system and recently implicated in autoimmunity. This observation may indicate that PTX3 participates in the inflammatory process of TAO. Methods All studies were performed on TAO patients and healthy controls (45: 28 in total). RNA-seq was used to detect differential gene expression of orbital adipose-connective tissue. Quantitative PCR was performed to verify the results. PTX3 protein in orbital adipose-connective tissues was visualized by immunohistochemistry (IHC). PTX3 concentration in serum was determined by enzyme-linked immunosorbent assay (ELISA). Results RNA-seq showed 1.86-log⁡2FC higher PTX3 expression in the orbital adipose-connective tissues from TAO group than controls (FDR = 0.0059). qPCR confirmed the difference (5.59-fold increase, p = 0.0012). The presence of PTX3 protein was demonstrated. Orbital adipose tissue from healthy controls showed weak staining for PTX3 while tissue from TAO group was strongly positive. Serum PTX3 concentration was significantly elevated in patients when compared to the control group (1.9-fold increase; p < 0.0001). Conclusions Patients with TAO showed increased presence of PTX3 in orbital tissue and serum, which may suggest a potential relationship of PTX3 and TAO. PMID:29675428

Ocorrência da ferrugem da videira em Minas Gerais

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Adelica Aparecida Xavier

2012-03-01

Full Text Available A ferrugem da videira causada por Phakopsora euvitis Ono constitui-se numa ameaça às regiões produtoras de uva em função do potencial destrutivo da planta. A doença foi detectada no Brasil, pela primeira vez, em 2001. Atualmente, ela ocorre no Paraná, Mato Grosso do Sul, São Paulo, Rio Grande do Sul, Mato Grosso, Roraima, Espírito Santo e Santa Catarina. Em abril de 2010, observaram-se na estação experimental da Unimontes, Janaúba, Minas Gerais, plantas da cv. Niágara rosada com sintomas típicos da doença. A análise dos sintomas e a caracterização dos urediniósporos sésseis, levemente equinulados, com formato oval, ou elipsoide formado em urédias subepidérmicas na origem, inrompentes e com paráfises circundantes dorsalmente, levaram à diagnose de Phakopsora euvitis como o agente causal da doença. Este é o primeiro relato da doença no Estado de Minas Gerais.

Environmental adaptation of the source of the subbasin of Rico Stream, Monte Alto - SP, Brazil Adequação ambiental da nascente da sub-bacia do Córrego Rico, Município de Monte Alto - SP

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Teresa C. T. Pissarra

2013-04-01

Full Text Available The aim of this study was to define the photographic patterns that represent the use and occupation of the landcover of the "spring" of the Rico Stream subbasin, located at Monte Alto, state of São Paulo (SP, Brazil, for environmental adaptation regarding the Brazilian Forest Law. The mapping was performed using remote sensing techniques and visual interpretation of the World View image, followed by the digitalization of the net of drainage and vegetation (natural and agricultural at the AutoCad software with documents and field work. The study area has 2141.53 ha and the results demonstrated that the main crop is sugarcane with 546.34 ha, followed by 251.22 ha of pastures, 191.71 ha of perennial crops, 57.31 ha of Eucalyptus and 49.52 ha of onion, confirming the advance of sugarcane culture in the region. The region has 375.04 ha of areas of permanent preservation (APPs, and of this area it was found that only 72.17 ha (19.24% has arboreal vegetation or natural forest, and 302.87 ha of these areas need to be enriched and reforested with native vegetation from the region, according to the current legislation. The data of the area enable future proposals of models for environmental adaptation to the microbasin according to the current environmental legislation.Este trabalho teve como principal objetivo definir padrões fotográficos que representem o uso e a ocupação do solo da "cabeceira" de drenagem do Córrego Rico, localizada no Município de Monte Alto, Estado de São Paulo, para fins de adequação ambiental no que tange à legislação florestal brasileira. O mapeamento foi realizado utilizando técnicas de sensoriamento remoto e interpretação visual da imagem World View, seguida da digitalização da rede de drenagem e vegetações (naturais e agrícolas no AutoCad, com auxílio de documentos e trabalho de campo. A área de estudo apresenta uma superfície de 2.141,53 ha, e os resultados permitiram constatar que a principal cultura �

A PROBLEMÁTICA DA BIOPIRATARIA: REFLEXÕES A PARTIR DA GEOPOLÍTICA E DOS DIREITOS DA SOCIOBIODIVERSIDADE

OpenAIRE

Nunes, Denise Silva; UFSM; Tybusch, Jerônimo Siqueira; UFSM

2013-01-01

O bioimperialismo configura-se como uma característica da geopolítica da atualidade, com alicerces nas estruturas da globalização e do capitalismo. Nesse contexto, a problemática da pesquisa consiste na violação dos direitos dos povos locais e a exploração do meio ambiente, em que o atual sistema internacional de propriedade intelectual contribui para a biopirataria dos recursos naturais, por meio da infiltração, em áreas ricas em diversidade biológica, das grandes corporações, multinacionais...

A dignidade da pessoa humana na doutrina social da igreja

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Manzone, Gianni

2010-01-01

Full Text Available O texto faz uma análise panorâmica sobre a compreensão da dignidade humana nos diversos textos da Doutrina Social da Igreja, mostrando o entendimento da mesma nos diversos documentos dos Papas, notadamente Leão XII, Pio XI, Pio XII e João Paulo II, além de apontar aspectos históricos e culturais que influenciaram cada pronunciamento, o que foi determinante para a evolução do pensamento do Magistério na questão social. O ponto de partida é a visão antropológica da Doutrina Social da Igreja, resumida em termos de “homem criado por Deus a sua imagem e resgatado pelo sangue de Jesus Cristo” (Sollicitudo Rei Socialis 29. A partir daí, há a defesa do primado do ser humano sobre o social e reivindicações totalitaristas que perpassaram a história recente da humanidade, embora a pessoa seja sempre um ser-em-relação e situado em uma sociedade determinada

As causas imediatas do crescimento da renda, da redução da desigualdade e da queda da extrema pobreza na Bahia, no Nordeste e no Brasil entre 2003 e 2011

OpenAIRE

de Souza, Pedro H. G. F.

2013-01-01

O objetivo deste trabalho é explicar as causas imediatas do crescimento da renda domiciliar per capita, da redução da desigualdade e da queda da extrema pobreza para cinco recortes geográficos – Brasil, Nordeste, Bahia, Região Metropolitana (RM) de Salvador e Bahia não metropolitana – durante o período recente de crescimento pró-pobre (2003-2011). Com base em decomposições dinâmicas dos três aspectos, este texto procura verificar se as mudanças dos últimos anos seguem ou não um mesmo padrão g...

Evapotranspiração da cultura da cebola

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G. M. Oliveira

2015-10-01

Full Text Available A determinação da quantidade de água necessária para as culturas é um dos principais fatores para o correto planejamento, dimensionamento e manejo de qualquer sistema de irrigação. O presente trabalho teve como objetivo, comparar medida da evapotranspiração da cultura (ETc da cebola com estimativa obtida a partir da evapotranspiração de referência (ETo determinada por diferentes métodos e Kc proposto na literatura. O experimento foi conduzido no campo experimental do Departamento de Tecnologia e Ciências Sociais da Universidade do Estado da Bahia - UNEB, em Juazeiro, no período de junho a setembro de 2011. As medidas da ETc foram obtidas em evapotranspirômetros e as estimativas, a partir de ETo determinada pelos métodos: Penman-Monteith (padrão FAO, Penman-Monteith modificado por Villa Nova et al. (2004, Hargreaves & Samani, Makkink e Jensen & Haise e Kc proposto por Marouelli et al. (2005, para a cultura da cebola. É fundamental a avaliação de métodos de estimativa da evapotranspiração de referência antes de sua aplicação, pois erros consideráveis podem ser cometidos na determinação da quantidade de água a ser aplicada a uma cultura, o que repercutirá certamente, na produtividade.Evapotranspiration crop onionAbstract: The determination of the amount of water needed for crops is a major factor for the correct planning, sizing and management of any irrigation system. This study aimed to compare measure of crop evapotranspiration (ETc onion with estimates obtained from the reference evapotranspiration (ETo determined by different methods and Kc proposed in the literature. The experiment was conducted in the experimental field of the Department of Technology and Social Sciences, University of the State of Bahia, in Juazeiro, from June to September 2011. The ETc measurements were obtained in evapotranspirometers and estimates, from ETo determined by the methods: Penman-Monteith (FAO standard, Penman-Monteith modified

Serum metabonomics study of anti-depressive effect of Xiao-Chai-Hu-Tang on rat model of chronic unpredictable mild stress.

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Xiong, Zhili; Yang, Jie; Huang, Yue; Zhang, Kuo; Bo, Yunhai; Lu, Xiumei; Su, Guangyue; Ma, Jie; Yang, Jingyu; Zhao, Longshan; Wu, Chunfu

2016-09-01

Xiao-Chai-Hu-Tang (XCHT) has been proven to be effective for the clinical treatment of depression. However, the mechanisms of definite antidepressant-like effects and detailed metabolic biomarkers were still unclear in this prior study. Here, we have investigated the metabolic profiles and potential biomarkers in a chronic unpredictable mild stress model after treatment with XCHT. Metabonomics based on ultra-high performance liquid chromatography coupled with mass spectrometry was used to profile the metabolic fingerprints of serum obtained from a rat model with chronic unpredictable mild stress with and without XCHT treatment. The model rats showed a significant decrease in sucrose preference and food consumption, and these depression-like symptoms were significantly improved by XCHT. Through principal component analysis (PCA), nine potential biomarkers of tryptophan, uric acid, phenylalanine, cholic acid and lysophosphatidylcholine (C18:0 LPC, C16:0 LPC, C16:1 LPC, C18:1 LPC, C20:4 LPC) were characterized as potential biomarkers involved the pathogenesis of depression. The therapeutic effect of XCHT on depression may involve in amino acid metabolism, lipid metabolism, oxidative stress and inflammation response. The present investigation highlights that metabonomics is a valuable tool for studying the essence of depression as well as evaluating the efficacy of the corresponding drug treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats

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Bailu Duan

2017-01-01

Full Text Available The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS, on experimental type 2 diabetes mellitus (T2DM rats and to explore its underlying mechanisms. Firstly two major chemical compositions of TKFS, gallic acid and curcumin, were characterized by HPLC fingerprint analysis. Next T2DM in rats was induced by high-fat diet and a low-dose streptozotocin (STZ 35 mg/kg. Then oral gavage administration of three different doses of TKFS (0.3 g/kg, 0.6 g/kg, and 1.2 g/kg was given to T2DM rats. Experimental results showed that TKFS dramatically reduced the levels of fasting blood glucose, fasting blood insulin, triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol, even though it did not alter the animal body weight. The downregulation of phosphorylation-AKT (p-AKT and glucose transporter-4 (GLUT4 in skeletal muscle of T2DM rats was restored and abnormal pathological changes in pancreas tissues were also improved. Our work showed that TKFS could alleviate diabetic syndromes, maintain the glucose homeostasis, and protect against insulin resistance in T2DM rats, and the improvement of AKT phosphorylation and GLUT4 translocation in skeletal muscle would be one of its possible underlying mechanisms.

How to Treat a Patient with Thromboangiitis Obliterans: A Systematic Review.

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Fazeli, Bahare; Dadgar Moghadam, Maliheh; Niroumand, Shabnam

2018-05-01

To date, there is still no treatment protocol for patients with thromboangiitis obliterans (TAO) who are also afflicted with critical limb ischemia (CLI). Smoking cessation on its own cannot be considered a treatment for the purposes of salvaging a limb of a TAO patient with CLI. The aim of this review was to evaluate different studies of various treatment protocols for avoiding amputation in TAO patients. A systematic search for relevant studies dating from 1990 to the end of 2016 was performed on the PubMed, SCOPUS, and Science Direct databases. Only 24 studies fulfilled the inclusion criteria, of which only one was a randomized controlled trial (RCT). The remaining studies were quasi-experimental with various treatments and follow-up durations. Therefore, meta-analysis was not performed. Judging from the major amputation rates after the suggested treatments were performed, no treatment was particularly effective. This review demonstrated that more standard RCTs are needed to resolve this treatment issue involved in TAO. In addition, because health insurance coverage for TAO patients differs by country, regional cost-benefit and cost-efficacy studies of the suggested treatments for TAO are highly recommended. Copyright © 2018 Elsevier Inc. All rights reserved.

76 FR 27861 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

Science.gov (United States)

2011-05-13

... Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG Airplanes... on Diamond aeroplanes, the majority of which were DA 40. In additional, at least 18 doors have been... conditions) while the aeroplane was parked. All DA 40 and DA 42 aeroplanes have a system installed that...

Utopia capitulada em cifra responsável e outros temas do cinema latino-americano hoje

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Sebastião Guilherme Albano da Costa

2012-12-01

Full Text Available Devido à escalada da racionalização no que tange aos processos de produção, distribuição e exibição de filmes na América Latina entre 1990 e 2011 e pela temeridade de se pensar uma teoria do cinema sem nos reportar a uma teoria do cinema como produção social, ideou-se denominar as consequências do Consenso de Washington nas forças políticas e econômicas que permeiam os regimes estéticos do audiovisual da região como formadoras de uma poética da responsabilidade. No plano da representação, por exemplo, a circunstância significou uma redução do repertório retórico (figuras etc. e parece haver instaurado (ou apenas acentuado a dependência simbólica de audiovisualidades hegemônicas.

A CENTRALIDADE DO TRABALHO E A TROCA ORGÂNICA ENTRE HOMEM E NATUREZA

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Andre André Luis Amorim de Oliveira

2013-12-01

Full Text Available Dentro do contexto da Terceira Revolução Industrial, marcada pela crise estrutural do capital, a centralidade do trabalho permanece sendo uma referência importante no que tange à compreensão histórica geográfica do papel da força de trabalho frente às mutações impostas pelo capital. Este artigo procura resgatar (e contribuir com alguns elementos importantes no que se refere à centralidade do trabalho num momento decisivo em que o capital tem exigido, cada vez mais, novos aparatos de gestão da força de trabalho, o que significa a ampliação da precarização do trabalho. Apresentamos também como elemento importante deste contexto uma aproximação do debate sobre a relação entre homem e natureza, considerando a centralidade do entendimento sobre o trabalho e sua polissemia.

Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang

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Mandy M. Liu

2017-03-01

Full Text Available Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT, comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular traditional Chinese medicines for women’s diseases. In our previous studies, the antioxidant Nrf2 pathways were strongly induced by SWT in vitro and in vivo. Since Nrf2 activation has been associated with anticarcinogenic effects, the purpose of this study is to evaluate SWT’s activity of cancer prevention. In the Ames test, SWT demonstrated an antimutagenic activity against mutagenicity induced by the chemical carcinogen 7,12-dimethylbenz(aanthracene (DMBA. In JB6 P+ cells, a non-cancerous murine epidermal model for studying tumor promotion, SWT inhibited epidermal growth factor (EGF-induced neoplastic transformation. The luciferase reporter gene assays demonstrated that SWT suppressed EGF-induced AP-1 and TNF-α-induced NF-κB activation, which are essential factors involved in skin carcinogenesis. In a DMBA-induced skin hyperplasia assay in ‘Sensitivity to Carcinogenesis’ (SENCAR mice, both topical and oral SWT inhibited DMBA-induced epidermal hyperplasia, expression of the proliferation marker Proliferating cell nuclear antigen (PCNA, and H-ras mutations. These findings demonstrate, for the first time, that SWT prevents tumor promoter and chemical-induced carcinogenesis in vitro and in vivo, partly by inhibiting DNA damage and blocking the activation of AP-1 and NF-κB.

Politics, culture, and the legitimacy of disease: the case of Buerger's disease.

Science.gov (United States)

Lockwood, Stephen J; Bresler, Scott C; Granter, Scott R

2016-09-01

Thromboangiitis obliterans (TAO) or Buerger's disease is a rare form of vasculitis with distinctive clinical and pathological features that carries significant morbidity, often leading to amputation, and is strongly associated with tobacco smoking. Despite its distinctive clinicopathological characteristics, the existence of TAO as an entity sui generis was challenged for many years as it languished in relative obscurity. Then, as societal attitudes towards smoking changed, TAO not only became accepted as a disease entity, it quite literally became a poster child to illustrate the ills of smoking. Herein, we examine the history of TAO to illustrate the power of societal attitudes and politics in shaping medicine.

SOBRE OS FUNDAMENTOS DA ARQUITETURA DA INFORMAÇÃO

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Alfram Roberto Rodrigues de Albuquerque

2011-10-01

Full Text Available Expõe-se o estado atual da disciplina Arquitetura da Informação quanto a problemática terminológica da definição do campo de estudo, apresentando-se argumentos para uma definição de Arquitetura da Informação de uma forma ampla na qual os usos correntes dessa expressão sejam vistos como especializações. Defende-se uma definição com a utilização de um conjunto de propriedades mínimas cujas interações levam a uma terminologia formal e cuja abstração leva a uma definição formal do conceito que emprega a linguagem de morfismos da Teoria das Categorias. Trata-se de um recorte de alguns dos resultados obtidos na tese de doutoramento de um dos autores, defendida em setembro de 2010. O contexto da pesquisa é exposto e alguns dos resultados obtidos são delineados.

76 FR 12627 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

Science.gov (United States)

2011-03-08

... Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG Airplanes AGENCY: Federal Aviation Administration (FAA... on Diamond aeroplanes, the majority of which were DA 40. In additional, at least 18 doors have been... conditions) while the aeroplane was parked. All DA 40 and DA 42 aeroplanes have a system installed that...

The effects of venting and decompression on Yellow Tang (Zebrasoma flavescens in the marine ornamental aquarium fish trade

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Emily S. Munday

2015-02-01

Full Text Available Each year, over 45 countries export 30 million fish from coral reefs as part of the global marine ornamental aquarium trade. This catch volume is partly influenced by collection methods that cause mortality. Barotrauma in fish resulting from forced ascent from depth can contribute to post-collection mortality. However, implementing decompression stops during ascent can prevent barotrauma. Conversely, venting (puncturing the swim bladder to release expanded internal gas following ascent can mitigate some signs of barotrauma like positive buoyancy. Here, we evaluate how decompression and venting affect stress and mortality in the Yellow Tang (Zebrasoma flavescens. We examined the effects of three ascent treatments, each with decompression stops of varying frequency and duration, coupled with or without venting, on sublethal effects and mortality using histology and serum cortisol measurements. In fish subjected to ascent without decompression stops or venting, a mean post-collection mortality of 6.2% occurred within 24 h of capture. Common collection methods in the fishery, ascent without decompression stops coupled with venting, or one long decompression stop coupled with venting, resulted in no mortality. Histopathologic examination of heart, liver, head kidney, and swim bladder tissues in fish 0d and 21d post-collection revealed no significant barotrauma- or venting-related lesions in any treatment group. Ascent without decompression stops resulted in significantly higher serum cortisol than ascent with many stops, while venting alone did not affect cortisol. Future work should examine links in the supply chain following collection to determine if further handling and transport stressors affect survivorship and sublethal effects.

A inclusão da subjetividade no ensino da Psicopatologia

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Octavio Domont de Serpa Junior

2007-08-01

Full Text Available O estudo da Psicopatologia tem sido freqüentemente apresentado em sua dimensão descritiva. Apesar da relevância para o ensino - auxiliar o aluno a reconhecer a dimensão sintomatológica dos quadros psicopatológicos -, exclui a dimensão subjetiva da experiência do adoecimento e seus aspectos relacionais. Partindo da tradição antropológico-existencial, apresentamos uma experiência de ensino de Psicopatologia que considera tais dimensões relevantes para a compreensão do sofrimento mental. Trabalhando com estudo de caso descritivo, são apresentadas duas novas modalidades de práticas na disciplina Psicopatologia Especial I, oferecida para alunos do curso de Psicologia da UFRJ. A proposta é ampliar o ensino prático, tradicionalmente centrado no modelo da extensa entrevista clínica, realizada diante de um grande grupo de alunos que a tudo assistem passivamente. Pretendemos aproximar o ensino e a prática da Psicopatologia dos ideais da Reforma Psiquiátrica Brasileira, que concebe o adoecimento mental como fenômeno complexo, envolvendo a relação do sujeito com o mundo.

Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign

Science.gov (United States)

Sliwoski, Gregory; Mendenhall, Jeffrey; Meiler, Jens

2016-03-01

Quantitative structure-activity relationship (QSAR) is a branch of computer aided drug discovery that relates chemical structures to biological activity. Two well established and related QSAR descriptors are two- and three-dimensional autocorrelation (2DA and 3DA). These descriptors encode the relative position of atoms or atom properties by calculating the separation between atom pairs in terms of number of bonds (2DA) or Euclidean distance (3DA). The sums of all values computed for a given small molecule are collected in a histogram. Atom properties can be added with a coefficient that is the product of atom properties for each pair. This procedure can lead to information loss when signed atom properties are considered such as partial charge. For example, the product of two positive charges is indistinguishable from the product of two equivalent negative charges. In this paper, we present variations of 2DA and 3DA called 2DA_Sign and 3DA_Sign that avoid information loss by splitting unique sign pairs into individual histograms. We evaluate these variations with models trained on nine datasets spanning a range of drug target classes. Both 2DA_Sign and 3DA_Sign significantly increase model performance across all datasets when compared with traditional 2DA and 3DA. Lastly, we find that limiting 3DA_Sign to maximum atom pair distances of 6 Å instead of 12 Å further increases model performance, suggesting that conformational flexibility may hinder performance with longer 3DA descriptors. Consistent with this finding, limiting the number of bonds in 2DA_Sign from 11 to 5 fails to improve performance.

Parâmetros erosividade da chuva, da enxurrada e da chuva-enxurrada correlacionados com as perdas de solo de um luvissolo

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A. W. Albuquerque

2002-09-01

Full Text Available Foram estudadas as correlações lineares simples, múltiplas e não-lineares entre os parâmetros erosividade da chuva, da enxurrada e da chuva-enxurrada e as perdas de solo provocadas por chuvas erosivas num Luvissolo. Os dados correspondentes ao período de 1986-1990 foram obtidos na estação experimental de Sumé (PB, pertencente à Universidade Federal da Paraíba - UFPB. Para determinar os parâmetros erosividade da chuva, da enxurrada e da chuva-enxurrada, foram analisadas chuvas individuais registradas em 136 pluviogramas. O volume de enxurrada isolado ou em combinação com características da chuva contribuiu, de forma significativa, para melhorar a estimativa das perdas de solo de chuvas individuais. Os parâmetros erosividade da chuva-enxurrada a(Vu α I30b; a(Vu α I5b; a(EIAb e da enxurrada a(Vub foram os melhores estimadores das perdas de solo para chuvas individuais. Dentre os parâmetros da erosividade da chuva, os que melhor se correlacionaram com as perdas de solo foram aqueles que incluíram o produto do volume da chuva pela intensidade máxima em trinta minutos a(VrI30.

CONTRIBUIÇÃO PARA O CONHECIMENTO DA GEOMORFOLOGIA DA CADEIA DA ARRÁBIDA (PORTUGAL: CARTOGRAFIA GEOMORFOLÓGICA E GEOMORFOMETRIA

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André Filipe Fonseca

2015-03-01

Full Text Available A cadeia da Arrábida resulta da interação de processos tectónicos e erosivos ao longo de um período de tempo alargado, situado entre o Miocénico médio e a atualidade. O desmantelamento da cadeia processou-se em função da componente de movimentação tectónica, da posição da linha de costa e dos processos erosivos a ela associados, desempenhando a rede hidrográfica um papel fundamental no restabelecimento do equilíbrio dinâmico entre processos endógenos e exógenos. Esta relação está expressa no escalonamento altitudinal de formas erosivas aplanadas e suspensas sobre a rede de drenagem atual, evidenciando uma evolução policíclica do relevo controlada pelo levantamento da Serra da Arrábida, pela subsidência do Sinclinal de Albufeira e pelas oscilações do nível do mar no decorrer do período plio-quaternário. Sobrepõe-se a este processo o rejogo vertical de falhas de orientação NNE-SSW a NE-SW evidenciando um aumento progressivo da deformação de oeste para leste. O presente trabalho pretende contribuir para o conhecimento da geomorfologia da cadeia da Arrábida recorrendo a técnicas de geomorfometria para a extração semiautomática e análise de formas de relevo. Dado o contexto morfotectónico, é dada particular atenção à interferência da tectónica na evolução do relevo.

A ÉTICA DA RESPONSABILIDADE E A PROTEÇÃO JURÍDICO-AMBIENTAL DAS FUTURAS GERAÇÕES NA CONSTITUIÇÃO FEDERAL DO BRASIL

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Juliana Rosa de Almeida

2013-06-01

Full Text Available Padrões de desenvolvimento tecnológico, baseados numa ética tradicional antropocêntrica, desencadearam sérios riscos à natureza, resultando numa ameaça à própria espécie humana. Tais questionamentos demandam uma inversão do agir humano, baseado no Princípio Responsabilidade, no que tange à necessidade de conservação da natureza para promover a garantia de sua existência futura. Dentre as principais formas de se aplicar tal responsabilidade está a atuação do Estado, através do direito em face da responsabilidade de criar as primeiras bases de aplicação de políticas públicas presentes que demandem projeções futuras e também que tenham como pré-condição os fundamentos de uma ética da responsabilidade. O Brasil, detentor de uma das maiores fontes de biodiversidade do mundo, possui em sua Carta Magna premissas que têm por escopo unir a proteção ambiental à qualidade de vida de presentes e futuras gerações, considerando, inclusive, que tal norma tenha a natureza de direito fundamental, o que corrobora para a necessidade de aplicação de uma Ética da Responsabilidade, no sentido de salvaguardar prudentemente os elementos presentes na natureza e consequentemente a existência de continuidade da espécie humana neste universo. Para tanto, objetiva-se no presente trabalho, bibliográfico e documental, estabelecer uma relação ético-jurídica entre um meio ambiente devidamente equilibrado e a qualidade de vida dos indivíduos presentes no território brasileiro, com base no contexto jurídico brasileiro atual, especificamente no que diz respeito à defesa do meio ambiente brasileiro presente no texto da Constituição Federal do Brasil, o que nos remete aos interesses intergeracionais e intrageracionais de proteção humana. Tais considerações são fundamentadas à luz da interpretação do Princípio Responsabilidade, tal como o concebera Hans Jonas, voltado para a integridade da existência humana baseada na

O uso da aromaterapia na melhora da autoestima

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Juliana Rizzo Gnatta

2011-10-01

Full Text Available Os objetivos deste estudo foram verificar se a inalação dos óleos essenciais de rosa e de ylang-ylang alteram a percepção da autoestima e comparar a eficácia dos mesmos. O projeto foi aprovado pelo Comitê de Ética em Pesquisa do Hospital da Universidade de São Paulo. Participaram 43 funcionários dos setores de Higienização e da Central de Materiais e Esterilização durante os meses de maio a julho de 2009. Os sujeitos foram randomizados em três grupos: dois que receberem os óleos essenciais e outro que recebeu placebo (essência de rosa. A avaliação da autoestima foi feita através de uma escala já validada no Brasil, sendo aplicada antes do uso dos aromas, depois de 30 dias de uso e ao completar 60 dias. Dentre os resultados, verificou-se que a amostra era constituída por 88,6% de indivíduos com média e alta autoestima e que os óleos essenciais em questão não alteraram de forma significativa a percepção da autoestima.

Da onda da gestão da qualidade a uma filosofia da qualidade da gestão: Balanced Scorecard promovendo mudanças

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Andréa Cavalcanti Correia Lima

2004-06-01

Full Text Available No final da década de 80 a Gestão da Qualidade Total (GQT era apresentada como capaz de resolver todos os problemas e atender a todas as necessidades da gestão das organizações. Buscando solucionar problemas de gestão não equacionados pela GQT, muitas organizações começam a adotar o Balanced Scorecard (BSC. Uma questão ainda não discutida com profundidade no mundo acadêmico é a viabilidade de integração desses dois modelos. O presente artigo discute a possibilidade de integração dessas duas ferramentas, verificando as melhorias que podem alcançar, principalmente no gerenciamento da estratégia da organização. Assim sendo, realizou-se estudo de caso no Caesar Park Hotel Fortaleza (CPHF, empresa que vêm adotando com sucesso os dois modelos. A pesquisa revela que é possível integrar os princípios da GQT com os do BSC, à medida que os fundamentos de ambos se complementam, sendo assim a utilização conjunta das ferramentas propicia melhor gerenciamento da estratégia da organização.In recent years, many organizations have been managed according to the principles of Total Quality Management (TQM, which became known around the globe in the 1980's, when looking for explanations for the so-called "Japanese miracle". TQM was presented as being capable of solving all problems and attending to all company management needs, a stage that seems outdated now. In the search for a model that would allow them to analyze and follow up the implementation of organizational strategies, without remaining limited to Quality indicators, many companies started to adopt the Balanced Scorecard (BSC. Companies using TQM question whether it is viable together with the BSC. In order to contribute to a solution to this question, this article discusses the possibility of aligning these two tools. Therefore, a case study was carried out at the Caesar Park Hotel Fortaleza, a company that implanted TQM in 1997 and started to adopt the BSC in 2000. The

Involvement of the Cerebral Monoamine Neurotransmitters System in Antidepressant-Like Effects of a Chinese Herbal Decoction, Baihe Dihuang Tang, in Mice Model

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Meng-Li Chen

2012-01-01

Full Text Available Baihe Dihuang Tang (BDT is a renowned Chinese herbal formula which is commonly used for treating patients with mental instability, absentmindedness, insomnia, deficient dysphoria, and other psychological diseases. These major symptoms closely associated with the depressive disorders. BDT was widely popular use for treating emotion-thought disorders for many years in China. In the present study, the antidepressant-like effect of BDT in mice was investigated by using the forced swim test (FST and the tail suspension test (TST. The underlying mechanism was explored by determining the effect of BDT on the level of cerebral monoamine neurotransmitters. BDT (9 and 18 g/kg, p.o. for 14 days administration significantly reduced the immobility time in both the FST and the TST without changing locomotion in the open field-test (OFT. Moreover, BDT treatment at the dose of 18 g/kg inhibited reserpine-induced ptosis. Meanwhile, BDT enhanced 5-HT and NA levels in mouse cerebrum as well as decreased the ratio of 5-HT compared to its metabolite, 5-HIAA, (turnover, 5-HIAA/5-HT after TST. The results demonstrated that the antidepressant-like effect of BDT is mediated, at least partially, via the central monoaminergic neurotransmitter system.

Mulheres Latino-Americanas e a Luta por Direitos Reprodutivos: o panorama da conjuntura política e legal do aborto nos países da América Latina.

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Paula Gonzaga

2015-12-01

Full Text Available A partir da década de 1960 a Segunda Onda do feminismo destacou a questão dos direitos ao corpo e ao livre exercício da sexualidade para as mulheres. Entre os temas de destaque as feministas pautaram a defesa da interrupção voluntária da gravidez como um direito das mulheres que deve ser garantido pelo Estado. Apesar do êxito obtido em grande parte da Europa, o avanço dessa discussão foi contido nos países latino americanos devido a predominância dos governos ditatoriais que perseguiram a organização dos movimentos sociais. Com a redemocratização o movimento feminista colocou novamente a questão do aborto em pauta, no entanto, novos arranjos políticos e disputas de poder contribuíram para que o aborto continue sendo considerado crime na maior parte da América Latina. Diante desse panorama o artigo tem por objetivo analisar a conjuntura política da América Latina no que tange aos avanços e retrocessos no campo dos direitos sexuais e reprodutivos das mulheres, enfocando na temática da descriminalização do aborto. A partir de um levantamento do estado da arte sobre essa temática em que se destacou a atuação dos discursos que atuam para a manutenção da criminalização do aborto ou que defendem que ele seja descriminalizado e legalizado. Palavras Chave: América Latina, Descriminalização do Aborto, Direitos Reprodutivos, Feminismo *** Abstract Since 1960s the Second Wave of feminism emphasized issues regarding the rights over the women´s own body and the free exercise of their sexuality. Beyond the highlighted topics, feminists guided the defense of the volunteer interruption of pregnancy as a women’s right that must be ensured by the State. Despite the success of this proposal across Europe, the progress of this discussion was restrained in Latin America due to the predominance of dictatorial governments which pursued the organization of social movements. With the redemocratization, the feminist movement brought

A Inovação Tecnológica na Sociedade do Conhecimento e o Papel Social da Embrapa no Desenvolvimento Regional

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Fabiana Cunha Viana Leonelli

2011-06-01

Full Text Available Em um ambiente caracterizado, cada vez mais, pelo acesso a informação e, principalmente, pela transversalidade do conhecimento, faz-se necessário compreender como a inovação tecnológica pode ter reflexos tangíveis e intangíveis na organização.A inovação pode ser entendida como a capacidade que a empresa tem em gerar novas idéias, identificar oportunidades e transformar esforços em produtos comercializáveis, buscando vincular a inovação com a geração de valor para a empresa, quase sempre, financeiro. No caso da Empresa Brasileira de Pesquisa Agropecuária – Embrapa, a geração de valor advinda das inovações se expressa não apenas pela arrecadação de royalties, mas, sobretudo, pelo avanço do conhecimento e pelos benefícios sociais e ambientais que uma tecnologia pode gerar para quem a adota, para o entorno e para a sociedade. Neste sentido, pensar a inovação tecnológica nesta dimensão é complexo e envolve elementos que extrapolam os fatores tradicionais de produção. A capacidade inovadora é formada por uma sinergia entre cultura organizacional, processos internos e relacionamentos inter-organizacionais.

Chromatographic isolation of nanoparticles from Ma-Xing-Shi-Gan-Tang decoction and their characterization.

Science.gov (United States)

Zhou, Jianwu; Gao, Guanzhen; Chu, Qiuping; Wang, Huiqin; Rao, Pingfan; Ke, Lijing

2014-02-12

The herbal decoction is a complex dispersion system containing solutes, colloid, aggregates, emulsions and precipitates. In which phase bioactive phytochemicals are dispersed determines their delivery, action and metabolism. This study took ephedrine, a well-studied and widely used phytochemical, as an example to elucidate its exact distribution in the phases of Ma-Xing-Shi-Gan-Tang decoction (MXSGT), which is an Ephedra sinica Stapf. containing traditional Chinese medicinal formula, and the biological meaning of this distribution correspondingly. It may provide an important update to the safety and efficacy assessment of the herbal decoction and its active phytochemicals. In this study, the decoction was fractionated with size-exclusion chromatography coupled with multi-angle laser light scattering detector. The morphology of fractionated nanoparticles was observed with AFM and SEM. The bioactivities of the decoction, the ephedrine alkaloids loaded NPs (prepared by chromatography isolation) and the synthetic ephedrine were assessed by cell proliferation tests using five cell lines, namely Caco-2, L-02, Hep-G2, NR-8383, and Hela-229. Nanoparticles with radii of gyration ranged from 50 to 150 nm were isolated, in spherical shape. Further analysis of nanoparticles on the subsequent reversed phase chromatography revealed that the majority of ephedrine (99.7%) and pseudoephedrine (95.5%) were associated with these nanoparticles, rather than dispersed freely in the real solution. The addition of both the herbal decoction and the separated ephedrine-loaded nanoparticles reserved higher cell viability/proliferation than that of the sole synthetic ephedrine among the Caco-2, L-02, Hep-G2, and NR-8383 cells. In contrast, the nanoparticles reduced the proliferating power of ephedrine on Hela-229 cells. In general, the ephedrine-loaded NPs conducted the intermediate influences on the cell viability, in either way. The colloidal nanoparticles were separated from the decoction

A Lei Maria da Penha sob a perspectiva da ética da vingança / Maria da Penha law unde the ethics of revenge approach

OpenAIRE

Nunes, Thaísa Silva de Oliveira; Faculdade de Direito de Vitória

2011-01-01

RESUMO: Analisa-se a lei 11.340/2006, conhecida como Lei Maria da Penha, sob a perspectiva da ética da vingança, considerando-se a situação de seu uso de forma equivocada. Nesse sentido, argui-se que o judiciário deve tomar um cuidado maior ao julgar casos de violência doméstica. Aborda-se também a possibilidade de uma mulher abandonada ou ultrajada pelo seu companheiro reagir de forma a resgatar a confiança em si, ao invés de se utilizar da prática da vingança permitida pelos mecanismos jurí...

A RELAÇÃO DA TELEVISÃO E DA INTERNET COM O CONSUMO: ANÁLISES DA IDEOLOGIA E DA CULTURA NAS PROPAGANDAS

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Fábio Carlos Rodrigues Alves

2016-10-01

Full Text Available Mais que um meio de comunicação, as tecnologias da comunicação, em especial a TV, transmitem valores, ideias e atitudes, ou seja, todo um conteúdo atitudinal e procedimental. O presente texto discute o papel da mídia televisiva e da internet na transmissão de valores culturais, atendo-se principalmente na questão do consumo. Analisamos propagandas oriundas do ambiente televisivo e também a veiculada pela internet a partir da qual objetivamos, à luz do conceito de Cultura e Ideologia investigar e assinalar o condicionamento dos consumidores ao ato de consumo.

O PAPEL DA ÁFRICA NA NOVA ROTA DA SEDA MARÍTIMA

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Diego Pautasso

2017-01-01

Full Text Available O objetivo do presente artigo é analisar o lugar da África na construção da Nova Rota da Seda Marítima. Este é justamente um dos vetores do ambicioso projeto chinês de integração da Ásia, Europa e África, lançada em 2013 sob título de Iniciativa OBOR (One Belt, One Road. Na medida que os desafios da reconstrução nacional são superados, a China torna-se mais assertiva e dá forma à sua estratégia de inserção mundial. Nesse sentido, a Nova Rota da Seda agrega os objetivos centrais da diplomacia da China para o século XXI, reservando à África a condição de trampolim para que o projeto se torne global.

ANÁLISE PRELIMINAR DA CONTROLADORIA DA CIDADE DE SALVADOR

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João Marcelo Pitiá Barreto

2012-06-01

Full Text Available A Controladoria tem sido alvo de estudos e destaque de análises e reflexões dos estudiosos das ciências que têm como foco o campo gerencial das organizações como a da Administração e Contabilidade. É importante observar a contribuição da Controladoria à governança pública, fundamento de uma gestão democrática e participativa. Nesse contexto, insere-se o objetivo deste estudo, refletir sobre atuação da controladoria pública da cidade de Salvador, observando a contribuição efetiva na governança nesse município. Os estudos foram desenvolvidos na Secretaria da Fazenda (SEFAZ do município a quem Controladoria vincula-se. Com caráter exploratório, essa investigação descritiva envolveu pesquisa de campo, análise de documentos e relatórios emitidos pela SEFAZ e pelo Tribunal de Contas do Município (TCM. Verificou-se o organograma da SEFAZ, seu orçamento e os pareceres do TCM. Os resultados expressam a importância da Controladoria e denotam a impressão de que, na instituição estudada, essa área não esteja cumprindo bem seu papel. 

UM ESTUDO DA INFLUÊNCIA DA GESTÃO DE PESSOAS NO DESEMPENHO DO TRABALHADOR E NA MELHORIA DA QUALIDADE

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Crislaine Carvalho

2017-01-01

Full Text Available A qualidade é uma das principais preocupações presentes dentro das organizações, e estas estão sempre à procura de ferramentas que possam auxiliar nesse processo. A influência da gestão de pessoas no desempenho do trabalhador pode ser um diferencial para as empresas no mercado competitivo. Este trabalho tem a finalidade de apresentar o relacionamento entre a gestão de pessoas e a gestão da qualidade e seus reflexos no processo de melhoria contínua. Nesse contexto, foi feita uma revisão bibliográfica da evolução histórica da qualidade e os reflexos da gestão de pessoas nesse processo. Foi estudado também uma evolução do termo Gestão de Pessoas e suas diversas nomenclaturas adotadas ao longo do tempo, e as influências dessas nomenclaturas no relacionamento com os funcionários. Essa pesquisa trouxe resultados positivos a respeito da influência da gestão de pessoas na melhoria da qualidade, mostrando que os interesses da empresa e dos funcionários podem sim caminhar juntos, desde que ambos os lados estejam satisfeitos, o que confirmou a hipótese inicial desse trabalho.

Influence of Jiang Tang Bu Shen Fang on expression of IKKβ mRNA in diabetic rats%降糖补肾方对糖尿病大鼠IKKβ mRNA表达的影响

Institute of Scientific and Technical Information of China (English)

范冠杰; 孙晓泽; 唐咸玉; 孙璐; 曾星; 罗广波; 卢绮韵; 温建炫

2011-01-01

目的 观察降糖补肾方对小剂量链脲佐菌素(STZ)加高脂饲料诱导的糖尿病模型大鼠肌肉组织IKK激酶β(IKKβ)信使核糖核酸(mRNA)表达的影响.方法 雄性SD大鼠高脂饲料喂养4周后注射小剂量STZ,1周后测大鼠空腹血糖,血糖值>11.1 mmoL/L者为造模成功的大鼠,将造模成功的大鼠随机分为模型组和降糖补肾方干预组,另设阿司匹林对照组和空白对照组,药物干预4周,取大腿肌肉组织,采用聚合酶链反应逆转录RT-PCR技术检测IKKβ mRNA表达水平.结果 模型组IKKβ mRNA表达明显高于空白对照组,是空白对照组的5.098倍(P0.05.结论 降糖补肾方在一定程度上能抑制糖尿病大鼠IKKβ mRNA基因,这可能是降糖补肾方抑制炎症信号通路的传导而发挥其改善胰岛素抵抗治疗糖尿病的机制之一.%Objective To observe the influence of Jiang Tang Bu Shen Fang on the expression of I kappa P kinase (IKKp) mRNA in muscular tissue in diabetic rats induced by low-dose streptozotocin ( STZ) and high-fat diet (HFD). Methods Male SD rats were fed HFD for 4 weeks, and then injected low-dose STZ. After one week the level of fasting plasma glucose was detected in rats and those with higher than 11. 1 mmol/L of level of fasting plasma glucose were successfully modeled. The rats were randomly divided into the model group, low-dose, mid-dose and high-dose Jiang Tang Bu Shen Fang groups (low-dose, mid-dose and high-dose groups), aspirin group and blank group. All groups were intervened by relevant medicinal for 4 weeks. The expression of IKKp mRNA in muscular tissue was detected by using reverse transcription polymerase chain reaction (RT-PCR). Results The expression of IKKp mRNA in the model group was significantly higher than that in the blank group (5.098 times, P 0. 05 compared with that in the model group. Conclusion Jiang Tang Bu Shen Fang can inhibit IKK(3 mRNA to some extent in diabetic rats, which may be one of mechanisms of the

Impacto do polimorfismo genetico da enzima conversora da angiotensina no remodelamento cardiaco

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Felipe Neves de Albuquerque

2014-01-01

Full Text Available Fundamento: O papel dos polimorfismos genéticos da enzima de conversão da angiotensina na insuficiência cardíaca, como preditor de desfechos ecocardiográficos, ainda não está estabelecido. é necessário identificar o perfil local para observar o impacto desses genótipos na população brasileira, sendo inédito o estudo da insuficiência cardíaca de etiologia exclusivamente não isquêmica em seguimento mais longo que 5 anos. Objetivo: Determinar a distribuição das variantes do polimorfismo genético da enzima de conversão da angiotensina e sua relação com a evolução ecocardiográfica de pacientes com insuficiência cardíaca de etiologia não isquêmica. Métodos: Análise secundária de prontuários de 111 pacientes e identificação das variantes do polimorfismo genético da enzima de conversão da angiotensina, classificadas como DD (Deleção/Deleção, DI (Deleção/Inserção ou II (Inserção/Inserção. Resultados: As médias da coorte foram: seguimento de 64,9 meses, idade de 59,5 anos, 60,4% eram homens, 51,4% eram brancos, 98,2% faziam uso de betabloqueadores e 89,2% de inibidores da enzima de conversão da angiotensina ou de bloqueador do receptor da angiotensina. A distribuição do polimorfismo genético da enzima de conversão da angiotensina foi: 51,4% de DD; 44,1% de DI; e 4,5% de II. Não se observou nenhuma diferença das características clínicas ou de tratamento entre os grupos. O diâmetro sistólico do ventrículo esquerdo final foi a única variável ecocardiográfica isolada significativamente diferente entre os polimorfismos genéticos da enzima de conversão da angiotensina: 59,2 ± 1,8 para DD versus 52,3 ± 1,9 para DI versus 59,2 ± 5,2 para II (p = 0,029. No seguimento ecocardiográfico, todas as variáveis (diferença entre a fração de ejeção do ventrículo esquerdo da última e da primeira consulta; diferença entre o diâmetro sistólico do ventrículo esquerdo da última e da primeira

"Geografia da Fome": da lógica regional à universalidade

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Arruda Bertoldo Kruse Grande de

1997-01-01

Full Text Available Geografia da Fome revela a associação harmoniosa da capacidade de argumentar com a segurança científica, um novo modo de pensar e de agir frente à realidade alimentar e nutricional e também uma abordagem pioneira no dimensionamento da fome coletiva como um fenômeno geograficamente universal. Admitiu, com base nas especificidades regionais, que as contribuições parciais poderiam compor um mapeamento caracterizador da universalidade do problema, permitindo construir uma imagem diferente do Brasil e do mundo, possibilitando a estruturação de um plano universal de combate à fome, abrindo novos caminhos para aqueles que buscam a correção de desequilíbrios regionais e a eliminação do subdesenvolvimento. Nesse livro-manifesto, Josué de Castro reinterpretou o papel da geografia clássica, incorporando uma das dimensões explicativas mais importantes, que é a da análise política, para desvendar a significação e conseqüências do desenvolvimento espacial desigual. A releitura de Geografia da Fome mostra que seus delineamentos conceituais e propositivos continuam vivos e constituem instrumentos indispensáveis para repensar criticamente a realidade brasileira e, em particular, a nordestina. Geografia da Fome, no seu cinqüentenário, torna-se um livro atual pela sua mensagem estimuladora e perturbadora.

"Geografia da Fome": da lógica regional à universalidade

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Bertoldo Kruse Grande de Arruda

1997-09-01

Full Text Available Geografia da Fome revela a associação harmoniosa da capacidade de argumentar com a segurança científica, um novo modo de pensar e de agir frente à realidade alimentar e nutricional e também uma abordagem pioneira no dimensionamento da fome coletiva como um fenômeno geograficamente universal. Admitiu, com base nas especificidades regionais, que as contribuições parciais poderiam compor um mapeamento caracterizador da universalidade do problema, permitindo construir uma imagem diferente do Brasil e do mundo, possibilitando a estruturação de um plano universal de combate à fome, abrindo novos caminhos para aqueles que buscam a correção de desequilíbrios regionais e a eliminação do subdesenvolvimento. Nesse livro-manifesto, Josué de Castro reinterpretou o papel da geografia clássica, incorporando uma das dimensões explicativas mais importantes, que é a da análise política, para desvendar a significação e conseqüências do desenvolvimento espacial desigual. A releitura de Geografia da Fome mostra que seus delineamentos conceituais e propositivos continuam vivos e constituem instrumentos indispensáveis para repensar criticamente a realidade brasileira e, em particular, a nordestina. Geografia da Fome, no seu cinqüentenário, torna-se um livro atual pela sua mensagem estimuladora e perturbadora.

Development and validation of a patient symptom questionnaire to facilitate early diagnosis of thyroid-associated orbitopathy in graves' disease.

Science.gov (United States)

Mohaseb, Kam; Linder, Mark; Rootman, Jack; Wilkins, G E; Schechter, Martin T; Dolman, Peter J; Singer, Joel

2008-01-01

To construct a patient-based symptom questionnaire to facilitate early referral of thyroid-associated orbitopathy (TAO) in Graves' hyperthyroidism (GH). Phase I of our study involved developing a symptomatology-based questionnaire for the self-reporting of TAO symptoms in patients recently diagnosed with GH. Phase II involved administering the questionnaire along with a standard ophthalmic examination to a screening cohort of patients newly diagnosed with GH. Symptoms highly associated with the clinical diagnosis of TAO were used to construct a tool with the highest possible sensitivity. Phase III involved validation of this tool in a new cohort of patients recently diagnosed with GH. For each patient, the diagnosis of TAO was made by both a standardized orbital ophthalmic exam and the questionnaire. Results from the questionnaire were then compared to the clinical examination. The questionnaire was compared to the standardized examination and found to have a sensitivity of 0.76 and a specificity of 0.82 in the validation phase of the study. This questionnaire may be a useful tool in clinical practice to allow identification of patients with TAO secondary to GH. Future studies using this questionnaire are needed to determine whether earlier identification and management of these patients is associated with reduced morbidity from TAO.

Influência da nutrição mineral foliar sobre doenças da parte aérea da cultura do trigo

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Rafael Gustavo Ferreira Morales

2012-02-01

Full Text Available A utilização de fungicida para o controle de doenças foliares na cultura do trigo é prática comum entre os triticultores. Contudo, devido ao impacto ambiental provocado pelo seu uso generalizado, buscam-se alternativas para controle dos fitopatógenos. Sendo assim, este trabalho teve como objetivo avaliar o efeito da nutrição mineral foliar sobre as doenças foliares do trigo, bem como seu efeito sobre o desenvolvimento da planta. O delineamento experimental foi em blocos casualizados com quatro repetições e quatro tratamentos: 1- testemunha; 2- adubação foliar aos 30 dias após a emergência (DAE e aos 75 DAE; 3- fungicida aos 30 e 75 DAE; e 4- adubação foliar aos 30 DAE e adubação foliar mais fungicida aos 75 DAE. Foram realizadas nove avaliações da incidência e da severidade do oídio, cujos dados foram utilizados para o cálculo das áreas abaixo das curvas de progresso da doença; três avaliações da severidade da ferrugem e da mancha da gluma; e duas avaliações da mancha amarela. Foram determinadas a massa de matéria fresca e seca da parte aérea e do sistema radicular e a produtividade da cultura. Foi observada redução da incidência e da severidade de oídio em função da adubação foliar, apenas na primeira avaliação de incidência e nas segunda e quinta avaliações de severidade da doença. O efeito complementar dos nutrientes com o fungicida para redução das doenças foi observado apenas para a mancha amarela, com redução de aproximadamente 11,16 % da severidade. Os maiores valores de produtividade foram observados para os tratamentos apenas com fungicida e, com fungicida mais nutrientes. A adubação foliar proporcionou aumento da massa fresca de raízes e massa seca de raízes. Apesar disso, não houve aumento da massa fresca da parte aérea em função da adubação foliar.

Role of green tea on nicotine toxicity on liver and lung of mice ...

African Journals Online (AJOL)

DR_Mohsen

2012-01-26

Jan 26, 2012 ... formation of lipid peroxidative products (Zhen et al.,. 2007). Antioxidant .... mg/kg green tea for three weeks showing normal lung structure with ..... injury in experimental model of carrageenan induced pleurisy in mice. Resp.

A aplicação dos recursos da seguridade social, a partir da perspectiva da teoria dos sistemas, da teoria comunicacional e do caos

OpenAIRE

Júnior, Dávio Antonio Prado Zarzana

2011-01-01

Este trabalho, focalizando o custeio da Seguridade Social, pretende realizar três verificações: a primeira, a existência ou não de desvios na aplicação dos recursos arrecadados para este financiamento, inclusive a partir da formulação de um conceito de desvio. A segunda, examinar os desequilíbrios que esses possíveis desvios produziriam, sob a ótica da Teoria dos Sistemas, utilizando-se, em adição, terminologia própria da Teoria Comunicacional. E a terceira, perscrutar a pos...

A Chinese Herbal Decoction, Danggui Buxue Tang, Stimulates Proliferation, Differentiation and Gene Expression of Cultured Osteosarcoma Cells: Genomic Approach to Reveal Specific Gene Activation

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Roy C. Y. Choi

2011-01-01

Full Text Available Danggui Buxue Tang (DBT, a Chinese herbal decoction used to treat ailments in women, contains Radix Astragali (Huangqi; RA and Radix Angelicae Sinensis (Danggui; RAS. When DBT was applied onto cultured MG-63 cells, an increase of cell proliferation and differentiation of MG-63 cell were revealed: both of these effects were significantly higher in DBT than RA or RAS extract. To search for the biological markers that are specifically regulated by DBT, DNA microarray was used to reveal the gene expression profiling of DBT in MG-63 cells as compared to that of RA- or RAS-treated cells. Amongst 883 DBT-regulated genes, 403 of them are specifically regulated by DBT treatment, including CCL-2, CCL-7, CCL-8, and galectin-9. The signaling cascade of this DBT-regulated gene expression was also elucidated in cultured MG-63 cells. The current results reveal the potential usage of this herbal decoction in treating osteoporosis and suggest the uniqueness of Chinese herbal decoction that requires a well-defined formulation. The DBT-regulated genes in the culture could serve as biological responsive markers for quality assurance of the herbal preparation.

Automatic locking orthotic knee device

Science.gov (United States)

Weddendorf, Bruce C. (Inventor)

1993-01-01

An articulated tang in clevis joint for incorporation in newly manufactured conventional strap-on orthotic knee devices or for replacing such joints in conventional strap-on orthotic knee devices is discussed. The instant tang in clevis joint allows the user the freedom to extend and bend the knee normally when no load (weight) is applied to the knee and to automatically lock the knee when the user transfers weight to the knee, thus preventing a damaged knee from bending uncontrollably when weight is applied to the knee. The tang in clevis joint of the present invention includes first and second clevis plates, a tang assembly and a spacer plate secured between the clevis plates. Each clevis plate includes a bevelled serrated upper section. A bevelled shoe is secured to the tank in close proximity to the bevelled serrated upper section of the clevis plates. A coiled spring mounted within an oblong bore of the tang normally urges the shoes secured to the tang out of engagement with the serrated upper section of each clevic plate to allow rotation of the tang relative to the clevis plate. When weight is applied to the joint, the load compresses the coiled spring, the serrations on each clevis plate dig into the bevelled shoes secured to the tang to prevent relative movement between the tang and clevis plates. A shoulder is provided on the tang and the spacer plate to prevent overextension of the joint.

Origin of the DA and non-DA white dwarf stars

Science.gov (United States)

Shipman, Harry L.

1989-01-01

Various proposals for the bifurcation of the white dwarf cooling sequence are reviewed. 'Primordial' theories, in which the basic bifurcation of the white dwarf sequence is rooted in events predating the white dwarf stage of stellar evolution, are discussed, along with the competing 'mixing' theories in which processes occurring during the white dwarf stage are responsible for the existence of DA or non-DA stars. A new proposal is suggested, representing a two-channel scenario. In the DA channel, some process reduces the hydrogen layer mass to the value of less than 10 to the -7th. The non-DA channel is similar to that in the primordial scenario. These considerations suggest that some mechanism operates in both channels to reduce the thickness of the outermost layer of the white dwarf. It is also noted that accretion from the interstellar medium has little to do with whether a particular white dwarf becomes a DA or a non-DA star.

Várias Marias: efeitos da Lei Maria da Penha nas delegacias

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Roberta Carvalho Romagnoli

2015-08-01

Full Text Available Este artigo discute os dados qualitativos da pesquisa “Violência Doméstica perpetrada contra a mulher no município de Montes Claros: um recorte possível”, financiada pelo CNPq e pela FAPEMIG. O objetivo do estudo foi investigar quantitativamente e qualitativamente os atos violentos contra as mulheres na cidade de Montes Claros, Minas Gerais. A vertente qualitativa pretendia conhecer o sentido da violência para as mulheres envolvidas e seus reflexos na família, através de entrevistas semiestruturadas que não se efetivaram. A partir da Análise Institucional de René Lourau analisamos essa inviabilidade como dado qualitativo, examinando o cotidiano da delegacia após a lei Maria da Penha. Concluímos que a intervenção judicial não é suficiente para a inibição da violência contra a mulher, pois em certos casos afasta da delegacia mulheres com outras demandas acerca da violência, que sofrem e que não podem contar com a ajuda policial para a resolução dos seus conflitos.

Implicações da visibilidade da enfermagem no exercício profissional

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Liziani Iturriet Avila

Full Text Available A construção da imagem da Enfermagem é permeada por aspectos históricos, socioeconômicos e culturais. Ao explorar esta temática, objetivou-se conhecer a percepção dos enfermeiros acerca da visibilidade do cotidiano de trabalho da equipe de enfermagem. Pesquisa qualitativa do tipo exploratória, com 30 enfermeiros de um hospital universitário do sul do país. Os dados foram coletados, de julho a outubro de 2012, através de entrevista semi-estruturada e submetidos à análise textual discursiva. Os resultados apontam que a visibilidade da Enfermagem está relacionada à trajetória histórica da profissão, à falta de reconhecimento da cientificidade da Enfermagem, à veiculação errônea na mídia, aos comportamentos inadequados perante a equipe e, ainda, à sobrecarga de trabalho. Assim, a desmistificação da imagem da profissão inclui uma busca de maior visibilidade midiática, realização de marketing pessoal, comportamento adequado perante a equipe de saúde e demonstração de autonomia profissional, desafios estes que deverão ser superados pela Enfermagem.

Modeling of Dust Levels Associated with Potential Utility-Scale Solar Development in the San Luis Valley-Taos Plateau Study Area

Energy Technology Data Exchange (ETDEWEB)

Chang, Y. -S. [Argonne National Lab. (ANL), Argonne, IL (United States); Kotamarthi, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Hartmann, H. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Patton, T. [Argonne National Lab. (ANL), Argonne, IL (United States); Finster, M. [Argonne National Lab. (ANL), Argonne, IL (United States)

2016-07-01

The San Luis Valley (SLV)–Taos Plateau study area in south-central Colorado and north-central New Mexico is a large alpine valley surrounded by mountains with an area of approximately 6,263,000 acres (25,345 km²) (Figure ES.1-1). This area receives ample sunshine throughout the year, making it an ideal location for solar energy generation, and there are currently five photovoltaic facilities operating on private lands in the SLV, ranging in capacity from 1 to 30 megawatt (MW). In 2012 the Bureau of Land Management (BLM) launched its Solar Energy Program, which included the identification of four solar energy zones (SEZs) in the SLV totaling 16,308 acres (66 km²), as well as over 50,000 (202 km²) acres of other BLM-administered lands potentially available for application for solar development. The SEZ areas, named Antonito Southeast, De Tilla Gulch, Fourmile East, and Los Mogotes East, were defined by the BLM as areas well-suited for utility-scale (i.e., larger than 20 MW) production of solar energy where solar energy development would be prioritized (BLM 2012). Nonetheless, it was recognized that solar development in the SEZs would result in some unavoidable adverse impacts, and so the BLM initiated a solar regional mitigation strategy (SRMS) study for three of the SEZs (BLM and Argonne 2016). The SRMS is designed to identify residual impacts of solar development in the SEZs (that is, those that cannot be avoided or minimized onsite), identify those residual impacts that warrant compensatory mitigation when considering the regional status and trends of the resources, identify appropriate regional compensatory mitigation locations and actions to address those residual impacts, and recommend appropriate fees to implement those compensatory mitigation measures.

Hanna Krall e os caminhos tortos da memória e da identidade

OpenAIRE

Piotr Kilanowski

2013-01-01

Neste artigo apresentamos a escritora polonesa de origem judaica Hanna Krall por meio da análise literária do seu romance Sublokatorka (A sublocatária).  O romance, com elementos autobiográficos, apresenta a personalidade cindida de uma menina sobrevivente do Holocausto e discute o tema da identidade polonesa, judaica e judaico-polonesa. Através da observação da memória e do processo de criação da memória, a autora mostra a construção da identidade falsa e a repressão da verdadeira, o comport...

Transaortic TAVI Is a Valid Alternative to Transapical Approach.

Science.gov (United States)

O' Sullivan, Katie E; Hurley, Eoghan T; Segurado, Ricardo; Sugrue, Declan; Hurley, John P

2015-05-01

Transcatheter aortic valve implantation (TAVI) can be performed via a number of different anatomical approaches based on patient characteristics and operator choice. The aim of this study was to compare procedural outcomes between transaortic (TAo) and transapical (TA) approaches in an effort to establish whether any differences exist. A systematic review and meta-analysis of the current literature reporting outcomes for patients undergoing TAo and TA TAVI was performed to compare outcomes using each vascular approach to valve deployment. A total of 10 studies and 1736 patients were included. A total of 193 patients underwent TAo and 1543 TA TAVI. No significant difference in 30-day mortality was identified (TAo 9.4, TA 10.4 p = 0.7). There were no significant differences identified between TAo and TA TAVI in procedural success rate (96.3% vs. 93.7% p = 0.3), stroke and transient ischemic attack (TIA) incidence (1.8% vs. 2.3% p = 0.7), major bleed (5.8% vs. 5.5% p = 0.97) or pacemaker insertion rates (6.1% vs. 7.4% p = 0.56). In addition, the incidence of clinically significant paravalvular regurgitation (PVR) was the same between groups (6.7% vs. 11% p = 0.43). Comparison of TAo and TA approaches revealed equivalent outcomes in 30-day mortality, procedural success, major bleeding, stroke/TIA incidence, pacemaker insertion rates and paravalvular leak. Heart teams should be familiar with the use of both TA and TAo access and tailor their selection on a case-to-case basis. © 2015 Wiley Periodicals, Inc.

Direito à palavra: interrogações acerca da proposta da justiça restaurativa

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Edson Luiz André de Sousa

Full Text Available Partindo da constatação da necessidade de alternativas ao sistema de Justiça atual, o presente artigo objetiva dar voz a uma das propostas que vem ganhando força no cenário jurídico mundial: a Justiça Restaurativa. Para tanto, este artigo explora essa proposta, promovendo uma análise crítica amparada em autores da psicanálise (freudo-lacaniana e da Filosofia (com F. Ost e J. Derrida. Através da Justiça Restaurativa, é possível questionar a potência da circulação da palavra, característica que promove o tensionamento entre psicanálise e Direito. Além disso, a questão da Lei e das leis, da performatividade dos atos da fala, da posição do Juiz, da experiência do encontro restaurativo e da função das utopias são os principais vieses que compõem esta análise. Mais voltado para a possibilidade de anunciar questionamentos sobre essa proposta tão nova no contexto brasileiro do que de encontrar respostas satisfatórias, este artigo mantém em suspenso várias conclusões, embora assuma a constatação da importante função utópica da Justiça Restaurativa.

Spatial distribution and source apportionment of water pollution in different administrative zones of Wen-Rui-Tang (WRT) river watershed, China.

Science.gov (United States)

Yang, Liping; Mei, Kun; Liu, Xingmei; Wu, Laosheng; Zhang, Minghua; Xu, Jianming; Wang, Fan

2013-08-01

Water quality degradation in river systems has caused great concerns all over the world. Identifying the spatial distribution and sources of water pollutants is the very first step for efficient water quality management. A set of water samples collected bimonthly at 12 monitoring sites in 2009 and 2010 were analyzed to determine the spatial distribution of critical parameters and to apportion the sources of pollutants in Wen-Rui-Tang (WRT) river watershed, near the East China Sea. The 12 monitoring sites were divided into three administrative zones of urban, suburban, and rural zones considering differences in land use and population density. Multivariate statistical methods [one-way analysis of variance, principal component analysis (PCA), and absolute principal component score-multiple linear regression (APCS-MLR) methods] were used to investigate the spatial distribution of water quality and to apportion the pollution sources. Results showed that most water quality parameters had no significant difference between the urban and suburban zones, whereas these two zones showed worse water quality than the rural zone. Based on PCA and APCS-MLR analysis, urban domestic sewage and commercial/service pollution, suburban domestic sewage along with fluorine point source pollution, and agricultural nonpoint source pollution with rural domestic sewage pollution were identified to the main pollution sources in urban, suburban, and rural zones, respectively. Understanding the water pollution characteristics of different administrative zones could put insights into effective water management policy-making especially in the area across various administrative zones.

Ferulic Acid Orchestrates Anti-Oxidative Properties of Danggui Buxue Tang, an Ancient Herbal Decoction: Elucidation by Chemical Knock-Out Approach.

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Amy G W Gong

Full Text Available Ferulic acid, a phenolic acid derived mainly from a Chinese herb Angelica Sinensis Radix (ASR, was reported to reduce the formation of free radicals. Danggui Buxue Tang (DBT, a herbal decoction composing of Astragali Radix (AR and ASR, has been utilized for more than 800 years in China having known anti-oxidative property. Ferulic acid is a major active ingredient in DBT; however, the role of ferulic acid within the herbal mixture has not been resolved. In order to elucidate the function of ferulic acid within this herbal decoction, a ferulic acid-depleted herbal decoction was created and named as DBTΔfa. The anti-oxidative properties of chemically modified DBT decoction were systemically compared in cultured H9C2 rat cardiomyoblast cell line. The application of DBT and DBTΔfa into the cultures showed functions in (i decreasing the reactive oxygen species (ROS formation, detected by laser confocal; (ii increasing of the activation of Akt; (iii increasing the transcriptional activity of anti-oxidant response element (ARE; and (iv increasing the expressions of anti-oxidant enzymes, i.e. NQO1 and GCLM. In all scenario, the aforementioned anti-oxidative properties of DBTΔfa in H9C2 cells were significantly reduced, as compared to authentic DBT. Thus, ferulic acid could be an indispensable chemical in DBT to orchestrate multi-components of DBT as to achieve maximal anti-oxidative functions.

Decreased absorption of midazolam in the stomach due to low pH induced by co-administration of Banha-sasim-tang

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Jun Hyeon Jo

2016-08-01

Full Text Available Objectives Banha-sasim-tang (BST, which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is often co-administered with other therapeutic drugs, which raises the possibility of herb–drug interactions and may modify the clinical safety profile of therapeutic drugs. Methods We investigated the potential herb–drug interactions between BST extract and midazolam (MDZ in mice. The area under the plasma concentration-time curve (AUC of MDZ and 1ʹ-hydroxymidazolam (1ʹ-OH-MDZ was evaluated for both oral and intraperitoneal administration of MDZ, following oral administration of BST (0.5 and 1 g/kg. Results It was found that the AUC of MDZ and 1ʹ-OH-MDZ was lower in case of oral administration of MDZ. Administration of BST extract was not associated with hepatic cytochrome P450 activity. BST extract induced a strong reduction in pH and it has been reported that oral mucosal absorption of MDZ is lower at low pH. The decreased absorption rate of MDZ might be caused by the ingredients of BST and may not be related to other factors such as increased excretion of MDZ by P-glycoprotein. Conclusions The altered pharmacokinetics of midazolam caused by co-administration with BST in vivo could be attributed to a decrease in pH and subsequent reduction of MDZ absorption rate.

Cruzeiros marítimos: realidade da oferta e da demanda no mercado brasileiro

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Carlos Eduardo de Almeida Ramoa

2014-12-01

Full Text Available O turismo marítimo apresenta uma demanda crescente e constante nos Estados Unidos e na Europa. No Brasil, esse mercado vinha se destacando com crescimento exponencial da demanda, no entanto, a partir da temporada 2011/2012 a taxa de crescimento tem apresentado queda. Este estudo de caráter exploratório e descritivo utiliza o método de procedimento matemático e tem como objetivo geral identificar a realidade da oferta e da demanda no mercado brasileiro de cruzeiros marítimos. Para atingi-lo foram identificados os históricos da oferta e da demanda, no período de 2004 a 2013, e da situação atual da infraestrutura portuária, através da utilização de técnicas de documentação indireta, procedimento documental e bibliográfico. Para se comparar a taxa de crescimento do mercado brasileiro com os principais mercados foi realizado cálculo da extrapolação matemática exponencial. Os resultados apresentados indicam que o Brasil é o único país entre os dez maiores mercados de cruzeiros marítimos, que possui taxa de crescimento negativo, indicando haver uma crise no segmento de cruzeiros marítimos, cujo motivo aponta para os problemas estruturais como sendo uma das causas da queda da oferta e da demanda no mercado brasileiro.

ESTATUTO PARADOXAL DA PELE E CULTURA CONTEMPORÂNEA: da porosidade à pele-teflon

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Maria Cristina Franco Ferraz

2014-06-01

Full Text Available A exploração do estatuto paradoxal da pele - interface dentro/fora - permite ultrapassar a dicotomia metafísica superfície/profundidade, problematizando a tendência atual, também expressa na teoria, a um elogio das superfícies e a um horror por oposições dicotômicas. Possibilta avaliar as implicações do fechamento da porosidade da pele em formas de sociabilidade estimuladas na cultura da imagem, da exibição, do espetáculo, bem expressas pelo material inorgânico teflon. Sendo Poros, na visão grega, pai de Eros, a investigação acerca do estatuto paradoxal da pele convida a uma retomada do tema do erotismo. Partindo de perspectivas oferecidas por Agamben acerca da pornografia, ligada ao valor de exibição nas sociedades de espetáculo e de consumo, e relacionando-as a diversas reflexões de José Gil acerca do corpo e da pele, discute-se e convoca-se a abertura da porosidade da pele.

ANÁLISE DA PAISAGEM DA BACIA HIDROGRÁFICA DO RIO ALMADA (BA COM BASE NA FRAGMENTAÇÃO DA VEGETAÇÃO

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Maria Eugênia Bruck de Moraes

2012-04-01

Full Text Available O estudo da fragmentação da paisagem em uma bacia é de extrema importância por avaliar o status de conservação da vegetação, um recurso essencial para a manutenção da qualidade da água. O presente trabalho apresenta uma análise da fragmentação da paisagem na Bacia Hidrográfica do Rio Almada, localizada no sul da Bahia, abrangendo 9 municípios parcialmente abastecidos pela água desta bacia. Foi realizado o mapeamento dos fragmentos florestais que apresentaram área mínima de 3ha, com base na interpretação da Carta de Uso e Cobertura do Solo elaborada através da classificação supervisionada de imagens Landsat. Para a análise dos fragmentos foram adotadas 5 métricas da paisagem: tamanho, formato, efeito de borda, isolamento e conectividade. Os resultados obtidos demonstram que a BHRA ainda abriga fragmentos bastante representativos, visto que dos 58 fragmentos identificados, 8 têm área acima de 300ha, 20 entre 100 e 300ha, 21 entre 30 e 100ha e 9 entre 3 e 30ha. Com relação ao formato dos fragmentos, constatou-se que apenas 10% dos mesmos apresentam forma circular, indicando que os 90% restantes encontram-se susceptíveis ao efeito de borda, sendo que os mais alongados estão localizados no interior da bacia, provavelmente em função do avanço da pecuária extensiva nessa direção. E quanto ao isolamento dos fragmentos, a análise da conectividade com borda expandida, através de simulações, permitiu identificar que a partir da distância de 200m, 31 dos fragmentos poderiam ser conectados. Assim, pôde-se concluir que o somatório destes fragmentos, caso fossem devidamente conectados, representaria uma área de significativo valor para a conservação de espécies típicas da mata atlântica e, consequentemente, para a manutenção da qualidade da água desta bacia.

ANÁLISE OPERACIONAL DA COLHEITA FLORESTAL NO SUL DA BAHIA

OpenAIRE

CARMO, F. C. A.

2013-01-01

CARMO, Flávio Cipriano de Assis. Análise operacional da colheita florestal no sul da Bahia. 2013. Dissertação (Mestrado em Ciências Florestais) Universidade Federal do Espírito Santo, Jerônimo Monteiro-ES. Orientador: Prof. Dr. Nilton César Fiedler. Coorientador: Profª. Drª. Elizabeth Neire da Silva Oliveira de Paula. Objetivou-se com esta pesquisa realizar uma análise operacional das atividades de colheita florestal em plantios de eucalipto no sul da Bahia. No estudo foram avaliados os ...

ESTIMAÇÃO DA IDADE DA REGENERAÇÃO DA VEGETAÇÃO DE CERRADO A PARTIR DE IMAGENS LANDSAT

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Philippe Maillard, Priscilla S. Costa-Pereira

2011-07-01

Full Text Available Nas regiões em que a rede de monitoramento hidrossedimentológico é precária ou inexistente, a utilização de modelos hidrológicos, de base física que proporcionem estimativas da geração de escoamento superficial e a perda de solo, se torna muito útil para fins de planejamento das bacias hidrográficas. O presente trabalho trata da aplicação do modelo hidrossedimentológico “Soil And Water Assessment Tool” nas Sub-Bacias 2 e 1 da Bacia Experimental de São João do Cariri. O modelo com a interface ArcSWAT, que se une ao SIG, necessita da entrada de “Modelo Digital de Elevação” (MDE da bacia e as simulações foram realizadas utilizando dois MDEs para fins de análise comparativa: um originado a partir da interpolação de dados de campo e outro obtido através de sensoriamento remoto. Com isto foi possível verificar a confiabilidade do uso de MDE obtido por sensoriamento remoto. Em nível das sub-bacias experimentais, foi realizada a parametrização, na Sub-Bacia 2, e a validação, na Sub-Bacia 1. O desempenho do modelo, para a geração da lâmina escoada, foi avaliado pelo coeficiente de determinação (R² e do fator da eficiência de Nash-Sutcliffe. Os resultados mostram desempenho satisfatório para ambos os MDEs, mostrando a pouca sensibilidade da topografia da geração de lâmina simulada em pequenas bacias. Por outro lado, a produção de sedimentos apresentou resultados insatisfatórios, além do que foi significativa a discrepância da distribuição da erosão do solo na superfície da bacia pelos dois MDEs utilizados.

COMPORTAMENTO DA ARRECADAÇÃO PRÓPRIA E DA CARGA TRIBUTÁRIA NOS MUNICÍPIOS DA ZONA DA MATA MINEIRA

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Anderson de Oliveira Reis

2016-06-01

Full Text Available O processo de descentralização consolidado pela constituição de 1988 mudou a dinâmica do federalismo brasileiro aumentando as receitas disponíveis e também as responsabilidades do fornecimento de serviços para os municípios, que em termos financeiros são muito dependentes das transferências governamentais. Diante da importância dos municípios na Administração Pública como entes federativos, este estudo tem como objetivo identificar, a partir da classificação em grupos, a mudança no perfil da arrecadação tributária própria dos municípios da Zona da Mata Mineira tendo por base os períodos de 2005 e 2010. Trata-se de pesquisa descritiva e quantitativa em que se utilizou as metodologias de Análise de Cluster e Teste t para amostras emparelhadas. Os resultados apontam para formação de 4 grupos de acordo com o esforço fiscal (baixo, médio e alto. Em média observa-se uma evolução positiva na arrecadação própria dos municípios que foi confirmada pelo Teste t. Conclui-se que apesar da dependência dos recursos de transferências, os municípios têm realizados esforços para aumentar a arrecadação própria e consequentemente suas receitas disponíveis.

GESTÃO DE FLUXOS DE INFORMAÇÃO EM AMBIENTE ORGANIZACIONAL

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Cássia Dias Santos

2014-08-01

Full Text Available Aborda as interconexões entre a gestão da informação e a gestão do conhecimento para o gerenciamento dos fluxos informacionais. A partir de uma revisão de literatura de modo a obter um embasamento que permita aclarar essa questão. Apresenta as peculiaridades que envolvem a gestão dos fluxos formais [gestão da informação] e dos fluxos informais [gestão do conhecimento], bem como os fatores que propiciam uma melhor compreensão no que tange ao foco da gestão da informação e da gestão do conhecimento. O gerenciamento eficiente dos fluxos informacionais demanda a necessidade de se implantar a gestão da informação e do conhecimento para sua real efetividade. Evidencia-se que esses dois modos de gestão se inter-relacionam de tal forma que, na ausência de uma a outra é afetada, repercutindo diretamente na gestão dos fluxos de informação e, assim, na capacidade de a organização gerar conhecimento e tomar decisões com diferencial competitivo.

IMPLICAÇÕES DA ANÁLISE V-A-T DA TEORIA DAS RESTRIÇÕES NA GESTÃO DA CADEIA DE SUPRIMENTOS

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Diego Augusto de Jesus Pacheco

2016-03-01

Full Text Available O objetivo dessa pesquisa é identificar o impacto da análise V-A-T da Teoria das Restrições na gestão estratégica de materiais à luz da Matriz de Posicionamento Estratégico dos Materiais (MPEM. A partir de dois estudos de caso, buscou-se verificar: i em qual classificação cada empresa se enquadrava dentro da lógica V-A-T, e ii se a gestão estratégica de materiais a partir da abordagem da MPEM pode ser considerada semelhante ou não nos casos investigados. Os resultados da pesquisa apontaram que a classificação V-A-T no caso da empresa S é do tipo A e no caso da empresa K é do tipo V. Já a análise da gestão estratégica de materiais a partir da MPEM, evidenciou que no caso S pertence ao quadrante não crítico e no caso K pertence ao quadrante estratégico. Identificou-se que a classificação V-A-T tende a impactar na gestão de materiais e no controle de estoques.

Influência da idade da planta e da maturação dos frutos no momento da colheita na qualidade do café

OpenAIRE

Borges,Fernanda Barbosa; Jorge,José Tadeu; Noronha,Regina

2002-01-01

São de grande importância os cuidados no preparo do café desde a colheita até o consumo e o estudo de parâmetros que possam influenciar na classificação comercial do grão e na qualidade da bebida. Teve-se como objetivos analisar a influência da idade das plantas, pertencentes à mesma variedade, e dos estágios de maturação dos grãos (secos, cerejas e verdes) no resultado da classificação comercial e na qualidade da bebida. Realizou-se a colheita, por derriça no pano, de uma área com café arábi...

CULTURA DIGITAL: UMA COMPREENSÃO DO PODER NAS PERCEPÇÕES ESTÉTICAS NO USO DAS TECNOLOGIAS EDUCACIONAIS DIGITAIS

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Marcelo Aparecido Freitas Vieira

2017-06-01

Full Text Available O trabalho apresenta como objetivos compreender a dimensão estética nos processos formativos e interpretar o desenvolvimento da autonomia e da emancipação dos sujeitos da “Geração Z” na Educação Básica, diante da utilização da Tecnologia Educacional Digital, a partir dos dados do CETIC.br. O referencial teórico adotado baseia-se em Adorno e Horkheimer, Schiller, Freire, Gadamer, os quais são adotados para o debate acerca da dimensão estética com destaque para a perspectiva de Papert e Lévy no que tange à Tecnologia da Informação e Comunicação. Os resultados são apresentados por meio das seguintes categorias: a estética do poder “Eu sei” da geração Z, A estética do poder do “Eu digital”. Em oposição, vislumbra-se uma possibilidade de libertação dos fenômenos midiáticos na ampliação de práticas instrumentais tecnológicas, a busca do caminho da conscientização da Cultura Digital no âmbito da relação do sujeito contemporâneo consigo mesmo, com o outro e com o mundo.

A decomposição do Estado e o protagonismo da sociedade civil no enfrentamento da questão social no Brasil: os dilemas da cidadania e da democracia na contemporaneidade

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Freire, Silene de Moraes

2006-01-01

Full Text Available O presente artigo foi elaborado a partir de preocupações profissionais voltadas para desvelar a presença e o enfrentamento, por parte do Estado e da sociedade civil, da questão social no cenário histórico-cultural da sociedade brasileira, evidenciado a partir da década de noventa, sobretudo, quando observamos a guinada do Estado brasileiro para a “mentalidade privatizante” que as reformas estruturais de cunho neoliberal promoveram. No caso brasileiro, tal projeto reafirma uma das particularidades de nossa cultura política: o moderno se constitui por meio do “arcaico”, recriando nossa herança histórica ao atualizar aspectos persistentes e, ao mesmo tempo, transformando-os no contexto da globalização. Pretendemos, assim, discutir de que modo a permanência histórica da desigualdade social, dos limites da cidadania e da democracia serviram como elemento facilitador para a implementação da agenda neoliberal no Brasil

Aspectos macroepidemiológicos da esquistossomose mansônica: análise da relação da irrigação no perfil espacial da endemia no Estado da Bahia, Brasil

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Martins Jr. Davi Félix

2003-01-01

Full Text Available Estudos na África, de forma enfática, têm mostrado a associação entre a implantação de perímetros de irrigação e o aumento ou expansão da ocorrência esquistossomose mansônica ou hematóbica. O objetivo deste estudo foi verificar a associação entre a prática de irrigação no território do Estado da Bahia e a ocorrência e a difusão da infecção pelo Schistosoma mansoni. O desenvolvimento da irrigação no Estado da Bahia assume duas formas: a primeira é intensiva em capital e mecanizada, voltada para produção agrícola de exportação e necessitando de pouca mão-de-obra. Na segunda forma, caracteriza-se pelo baixo grau de mecanização e utilização intensiva de mão-de-obra. O estudo mostrou que os municípios com as maiores áreas irrigadas não são aqueles que registram as mais altas taxas de prevalência da infecção. Na maior parte desses municípios a irrigação é intensiva em termos de capital e tecnologia. Os achados concluem que diferentemente do observado na África, no Estado da Bahia, a irrigação tem tido pequena influência na definição do perfil espacial da endemia.

Immunomodulatory effects of Longdan Xiegan Tang on CD4+/CD8+ T cells and associated inflammatory cytokines in rats with experimental autoimmune uveitis.

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Tang, Kai; Guo, Dadong; Zhang, Lian; Guo, Junguo; Zheng, Fengming; Si, Junkang; Bi, Hongsheng

2016-09-01

Longdan Xiegan Tang (LXT) is a mixture of herbal extracts commonly used in traditional Chinese medicine that may exert immunomodulatory effects for the treatment of autoimmune diseases. However, the detailed mechanisms that mediate the actions of LXT are unclear. The present study induced an experimental autoimmune uveitis (EAU) model in Lewis rats via injection of IRBP1177‑1191 emulsion. The model was used to investigate the effects of LXT on EAU rats and assess the efficacy of LXT by measuring clinical manifestations and histopathological changes caused by EAU. Additionally, alterations in the ratio of CD4+/CD8+‑T cells were determined by flow cytometry, and the expression of interferon (IFN)‑γ, interleukin (IL)‑17, IL‑10 and tumor necrosis factor (TNF)‑α were measured using reverse transcription‑quantitative polymerase chain reaction and enzyme‑linked immunosorbent assay analysis. The results of the present study demonstrate that LXT can efficiently alleviate the symptoms of EAU, inhibit the differentiation of uveitogenic CD4+ T cells and reduce the expression of proinflammatory cytokines, including IFN‑γ, IL‑17 and TNF‑α. Furthermore, LXT promotes the production of IL‑10 and accelerates the recovery of EAU, indicating that the immunomodulatory effects of LXT may potentially be used for the treatment of uveitis.

Da possibilidade de uma Teoria Pura da Ciência da Informação: reflexões iniciais entre a Ciência da Informação e a Ciência do Direito

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Max Cirino de Mattos

Full Text Available O artigo discute a fragilidade epistemológica da Ciência da Informação, a partir da adoção de um termo polissêmico, como objeto científico, e a similaridade dessa situação com o contexto da criação da Teoria Pura do Direito de Hans Kelsen. Após a apresentação de algumas definições sobre o objeto da Ciência da Informação, discutem-se alguns reflexos relacionados à identidade científica e à fundamentação teórica derivadas de um objeto polissêmico. Apresenta-se uma breve introdução à Teoria Pura do Direito e algumas reflexões sobre a possibilidade de uma Teoria Pura da Ciência da Informação.

Desempenho escolar: uma análise do IDEB dos municípios da região do ABC

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Paulo Sérgio Garcia

2016-08-01

ção Básica (IDEB, criado em 2007, que combina o desempenho dos alunos no Sistema Nacional de Avaliação (SAEB, para os estados, e na Prova Brasil, para os municípios, e o fluxo escolar. Este estudo analisa o IDEB dos municípios que formam a região do ABC paulista, realizando várias comparações por meio de metodologia mista. Analisou-se o índice, em cada uma das cidades, referente ao nível de Ensino Fundamental I e II. Foram considerados, na análise, o desenvolvimento das escolas, no que tange ao alcance das metas estipuladas pelas diferentes esferas administrativas e pelo INEP, e as proporções de alunos que atingiram o nível adequado na competência de leitura e interpretação de texto e na de resolução de problemas. Concomitantemente, foram analisadas, junto aos diretores das escolas, informações que contextualizassem os dados quantificados. Os resultados mostraram evolução gradual e contínua do índice no Ensino Fundamental I, nas esferas municipal e estadual, e crescimento ínfimo ou estagnação no Fundamental II. Uma realidade ainda mais dura se apresenta na aprendizagem da matemática. Na contextualização dos dados, a ausência de continuidade positiva dos resultados do Fundamental I para o II foi atribuída às características de cada segmento como o número de professores, o tipo de tratamento dado ao jovem, os métodos utilizados, as referências compartilhadas e aceitas, a organização da escola e a gestão escolar. Esses dados podem auxiliar as escolas no aprimoramento qualitativo da educação nas cidades da região.

A LEITURA DA GRAMÁTICA DA FORMA DO CONJUNTO HABITACIONAL CAMPINAS-F DA CDHU EM CAMPINAS

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Marcelo de Morais

2014-12-01

Full Text Available A gramática da forma constitui uma importante ferramenta que pode dar suporte para futuros estudos e melhor qualidade em conjuntos habitacionais. A utilização de sistemas generativos de projeto pode aperfeiçoar uma série de rotinas de projeto, potencializando seu uso com outras ferramentas de informática. Este trabalho apresenta os resultados de estudo exploratório com um sistema generativo de projeto em processo de simulação e imersão, por meio do qual se pode avaliar o desenvolvimento e as alterações do projeto de implantação de conjunto habitacional social, ocasionadas pela variação das regras nos algoritmos criados. Inicialmente, se realizou a leitura Analítica da Gramática da Forma de um Conjunto Habitacional específico e, posteriormente, simulou-se em ferramenta computacional a Gramática da Forma Paramétrica, para futuros estudos de melhorias em conjuntos habitacionais similares. Tal ferramenta visa desenvolver soluções inovadoras em tecnologia da informação e comunicação aplicadas à construção e arquitetura. Os resultados demonstram a potencialidade do uso da Gramática da Forma, permitindo a inserção de novos parâmetros a cada momento, criando a perspectiva de flexibilidade na concepção e gerando diversas possibilidades que podem ser analisadas e comparadas durante o processo de tomada de decisão do projeto.

A Sintaxe da Janela

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Luís Antônio Jorge

1993-12-01

Full Text Available A preocupação fundamenta! do trabalho é de caráter ontológico: esboçar o problema das significações apriorísticas e autônomas dos elementos que compõem a sintaxe arquitetônica. O trabalho elege um desses elementos: a janela. Este artigo parte da aproximação histórica entre a janela e a secção da pirâmide visual, construção imaginária da teoria da perspectiva renascentista. A consideração da janela na linguagem arquitetônica implica reconhecer uma ambigüidade essencial: a janela deve inserir-se ordenadamente no plano da parede - raciocínio típico da modenatura - mas também relacionar-se com a imagem vista através dela, que extrapola o plano, ressaltando a tridimensionalidade - herança da perspectiva renascentista, fundamentada no espaço euclidiano. Ver janela ou ver através da janela são alternativas que se colocam tanto ao observador interno ao edifício, quanto ao externo. Texto de duplaface, a sintaxe da janela versa sobre o relacionamento desses dois lados

A rapid method for simultaneous determination of 52 marker compounds in Xiao-Qing-Long-Tang by ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.

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Zhou, Lei; Qi, Wen; Xu, Cong; Makino, Toshiaki; Yuan, Dan

2014-11-01

Xiao-Qing-Long-Tang (XQLT) is a classical Chinese medicine formula. It is generally used for the treatment of common cold, bronchial asthma, and allergic rhinitis in Asia. In this study, a multicomponent quantification fingerprinting approach based on ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry has been developed for the analysis of compounds in XQLT in 14.5 min. A total of 52 compounds were identified by co-chromatography of sample extract with authentic standards and comparing the retention time, UV spectra, molecular ions and characteristic fragment ions with those of authentic standards, or tentatively identified by MS(E) determination along with Mass Fragment software. Moreover, the method was validated for the simultaneous quantification of 16 components in XQLT commercial products. The method is practical for comprehensive standardization of XQLT and holistic comparison of its commercial products from different manufacturers. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

ANÁLISE EXPERIMENTAL DA INFLUÊNCIA DA TECNOLOGIA HOMEPLUG NA QUALIDADE DA ENERGIA ELÉTRICA

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Antonio Luiz Pereira de Siqueira Campos

2008-03-01