Estimated ventricle size using Evans index: reference values from a population-based sample.

Science.gov (United States)

Jaraj, D; Rabiei, K; Marlow, T; Jensen, C; Skoog, I; Wikkelsø, C

2017-03-01

Evans index is an estimate of ventricular size used in the diagnosis of idiopathic normal-pressure hydrocephalus (iNPH). Values >0.3 are considered pathological and are required by guidelines for the diagnosis of iNPH. However, there are no previous epidemiological studies on Evans index, and normal values in adults are thus not precisely known. We examined a representative sample to obtain reference values and descriptive data on Evans index. A population-based sample (n = 1235) of men and women aged ≥70 years was examined. The sample comprised people living in private households and residential care, systematically selected from the Swedish population register. Neuropsychiatric examinations, including head computed tomography, were performed between 1986 and 2000. Evans index ranged from 0.11 to 0.46. The mean value in the total sample was 0.28 (SD, 0.04) and 20.6% (n = 255) had values >0.3. Among men aged ≥80 years, the mean value of Evans index was 0.3 (SD, 0.03). Individuals with dementia had a mean value of Evans index of 0.31 (SD, 0.05) and those with radiological signs of iNPH had a mean value of 0.36 (SD, 0.04). A substantial number of subjects had ventricular enlargement according to current criteria. Clinicians and researchers need to be aware of the range of values among older individuals. © 2017 EAN.

Spectral Uncertainties: A Review of Precarity and Loss: On Certain and Uncertain Properties of Life and Work by Tadeusz Rachwał

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Edyta Lorek-Jezińska

2017-10-01

Full Text Available Precarity and uncertainty recur in numerous critical accounts of the present to stress the sense of social and personal insecurity resulting from global changes and increasing inequalities. This review discusses Precarity and Loss: On Certain and Uncertain Properties of Life and Work by Tadeusz Rachwał (2017 as an examination of the major philosophical and social uncertainties of the present and their indebtedness to the (uncertainties of the past. The article situates Rachwał’s book in the context of Judith Butler’s reflections on precariousness, Guy Standing’s study on the precariat, and Zygmunt Bauman’s concept of liquidity in order to unravel some of the answers it offers to the overpowering sense of vulnerability.

Experience with Evans syndrome in an academic referral center

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José Carlos Jaime-Pérez

2015-08-01

Full Text Available OBJECTIVE: To document the experience of one referral service with patients diagnosed with Evans syndrome, the treatment and response and to briefly review current treatment strategies and results.METHODS: Patients enrolled in this study fulfilled criteria for Evans syndrome. Data were retrieved from the clinical files and electronic databases of the Department of Hematology, Hospital Universitario "Dr. José Eleuterio González". Treatment modalities and response and the use of additional therapies were evaluated. The literature was reviewed in the context of the clinical course of the studied patients.RESULTS: Six patients were diagnosed with Evans syndrome in the study period. Patient 1 was treated with steroids, relapsed twice and was again treated with steroids. Patient 2 treated initially with steroids plus intravenous immunoglobulin was subsequently lost to follow-up. A good response was achieved in Patients 3 and 4, who were treated with steroids plus rituximab; patient 4 also received danazol as a second-line therapy. However both relapsed and subsequently underwent splenectomy at ten and nine months, respectively. One patient, number 5, treated with steroids, danazol and rituximab did not relapse within four years of follow-up and Patient 6, who received steroids plus danazol did not relapse within three years of follow-up.CONCLUSION: Evans syndrome is an uncommon hematologic condition rarely diagnosed and not widely studied. Clinicians must have it in mind when evaluating a patient with a positive direct antiglobulin test, anemia and thrombocytopenia, since prognosis depends on its early recognition and opportune therapy, but even this leads to variable results.

Hiro and Evans currents in Vertical Disruption Event

Science.gov (United States)

Zakharov, Leonid; Xujing Li Team; Sergei Galkin Team

2014-10-01

The notion of Tokamak Magneto-Hydrodynamics (TMHD), which explicitly reflects the anisotropy of a high temperature tokamak plasma is introduced. The set of TMHD equations is formulated for simulations of macroscopic plasma dynamics and disruptions in tokamaks. Free from the Courant restriction on the time step, this set of equations is appropriate for high performance plasmas and does not require any extension of the MHD plasma model. At the same time, TMHD requires the use of magnetic field aligned numerical grids. The TMHD model was used for creation of theory of the Wall Touching Kink and Vertical Modes (WTKM and WTVM), prediction of Hiro and Evans currents, design of an innovative diagnostics for Hiro current measurements, installed on EAST device. While Hiro currents have explained the toroidal asymmetry in the plasma current measurements in JET disruptions, the Evans currents explain the tile current measurements in tokamaks. The recently developed Vertical Disruption Code (VDE) have demonstrated 5 regimes of VDE and confirmed the generation of both Hiro and Evans currents. The results challenge the 24 years long misinterpretation of the tile currents in tokamaks as ``halo'' currents, which were a product of misuse of equilibrium reconstruction for VDE. This work is supported by US DoE Contract No. DE-AC02-09-CH1146.

Automated method to compute Evans index for diagnosis of idiopathic normal pressure hydrocephalus on brain CT images

Science.gov (United States)

Takahashi, Noriyuki; Kinoshita, Toshibumi; Ohmura, Tomomi; Matsuyama, Eri; Toyoshima, Hideto

2017-03-01

The early diagnosis of idiopathic normal pressure hydrocephalus (iNPH) considered as a treatable dementia is important. The iNPH causes enlargement of lateral ventricles (LVs). The degree of the enlargement of the LVs on CT or MR images is evaluated by using a diagnostic imaging criterion, Evans index. Evans index is defined as the ratio of the maximal width of frontal horns (FH) of the LVs to the maximal width of the inner skull (IS). Evans index is the most commonly used parameter for the evaluation of ventricular enlargement. However, manual measurement of Evans index is a time-consuming process. In this study, we present an automated method to compute Evans index on brain CT images. The algorithm of the method consisted of five major steps: standardization of CT data to an atlas, extraction of FH and IS regions, the search for the outmost points of bilateral FH regions, determination of the maximal widths of both the FH and the IS, and calculation of Evans index. The standardization to the atlas was performed by using linear affine transformation and non-linear wrapping techniques. The FH regions were segmented by using a three dimensional region growing technique. This scheme was applied to CT scans from 44 subjects, including 13 iNPH patients. The average difference in Evans index between the proposed method and manual measurement was 0.01 (1.6%), and the correlation coefficient of these data for the Evans index was 0.98. Therefore, this computerized method may have the potential to accurately compute Evans index for the diagnosis of iNPH on CT images.

Comics Activism: An Interview with Comics Artist and Activist Kate Evans

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Dominic Davies

2017-11-01

Full Text Available This is an interview with comics artist Kate Evans, author of 'Red Rosa' (2015 and 'Threads: From the Refugee Experience' (2017, as well as a number of other comics, about her recent work, which operates at the intersection of several of the most exciting genre developments in comics in recent years. In the interview Evans reflects on recent shifts in comics journalism, as well as other trends in the field such as the rise of graphic memoir, through examples taken from Evans’s own work as well as that of Joe Sacco, Lynda Barry, Alison Bechdel and others.

Soul / Randy Becker, Bill Evans, Evelin Samuel ; interv. Sven Sapelson

Index Scriptorium Estoniae

Becker, Randy

2007-01-01

The Soulbop Bandi rajajad Randy Becker ja Bill Evans ning meie Evelin Samuel gospeli ja rhytmblues'i juurtega soulist. Lk. 72-73 Inessa Josingu ja Ande Kaalepi souliteemaline fotolavastusega ruumikujundus

Optimizing the Internal Medicine Clinic at Evans Army Community Hospital

National Research Council Canada - National Science Library

Bonilla, Jose

2003-01-01

...) 2002, the Internal Medicine (IM) clinic at Evans Army Community Hospital, Fort Carson, Colorado, failed to meet access to care standards for routine appointments, and was only marginally successful in meeting standards for urgent appointments...

O fantasma de Evans-Pritchard: diálogos da antropologia com a sua história The ghost of Evans-Pritchard: anthropology’s dialogues with its own history

Directory of Open Access Journals (Sweden)

Frederico Delgado Rosa

2011-06-01

Full Text Available Tomando como estudo de caso a monografia de Sharon Hutchinson sobre os nuer, o presente artigo explora os quiproquós do diálogo entre a antropologia contemporânea e os clássicos, procurando detetar certas genealogias invisíveis que remontam aos funcionalistas britânicos, e nomeadamente a Evans-Pritchard. Procede a um esbatimento de certas oposições explícitas entre o presente e o passado da antropologia, revelando que as noções clássicas perpassam de forma subterrânea o discurso daqueles que dizem rejeitá-las e que muitas das preocupações atuais já tinham expressão nas etnografias modernas. É demonstrado que as abordagens estáticas - como a de Evans-Pritchard - tinham uma componente histórica e que a antropologia social britânica teve as suas respostas teóricas e metodológicas para as transformações dos contextos africanos sob domínio colonial.Through the reading of Sharon Hutchinson’s monograph on the Nuer, this article explores the misunderstandings between contemporary anthropology and the modern classics. It tries to identify invisible genealogies that go back to the British functionalists, particularly to Evans-Pritchard, and minimizes the explicit oppositions between the present and the past of anthropology. It reveals that some classical notions are detectable in non-explicit ways among those who claim to reject them and, at the same time, that contemporary concerns have their roots in modern ethnographies. The author shows that static approaches - as the one by Evans-Pritchard on the Nuer - had a historical meaning and recalls that British social anthropology had its own theoretical and methodological answers to the transformations of African contexts under colonial rule.

Challenging Expertise: Paul Feyerabend vs. Harry Collins & Robert Evans on democracy, public participation and scientific authority: Paul Feyerabend vs. Harry Collins & Robert Evans on scientific authority and public participation.

Science.gov (United States)

Sorgner, Helene

2016-06-01

This paper compares Feyerabend's arguments in Science in a Free Society to the controversial theory of expertise proposed by Harry Collins and Robert Evans as a Third Wave of Science Studies. Is the legitimacy of democratic decisions threatened by the unquestioned authority of scientific advice? Or does, on the contrary, science need protection from too much democratic participation in technical decisions? Where Feyerabend's political relativism envisions democratic society as inherently pluralist and demands equal contribution of all traditions and worldviews to public decision-making, Collins and Evans hold a conception of elective modernism, defending the reality and value of technical expertise and arguing that science deserves a privileged status in modern democracies, because scientific values are also democratic values. I will argue that Feyerabend's political relativism provides a valuable framework for the evaluation of Collins' and Evans' theory of expertise. By constructing a dialog between Feyerabend and this more recent approach in Science and Technology Studies, the aim of this article is not only to show where the two positions differ and in what way they might be reconciled, but also how Feyerabend's philosophy provides substantial input to contemporary debate. Copyright © 2015 Elsevier Ltd. All rights reserved.

Lyn Evans decelerates!

CERN Multimedia

CERN Bulletin

2010-01-01

After more than 40 years at CERN, 15 of which were dedicated to ensuring that the LHC comes to completion, Lyn Evans is retiring. The Imperial College Professor and recently-elected Fellow of the British Royal Society has set himself new challenges, but plans to keep strong links with CERN. His big thank you goes to the many hundreds of people who built one of the most complex scientific instruments ever conceived by mankind. Note from the Editor: It is unusual for the Bulletin to adopt a question-and-answer style. However, we recognise that, with someone of Lyn’s stature, the appropriate thing to do is simply to give him the floor. Bulletin: Lyn, are you really leaving CERN? I am retiring but I will not completely lose contacts with CERN and the LHC. It’s time to slow down for me now but I will join the CMS Collaboration. I will help with the link between the experiment and the machine. Bulletin: After many years as LHC Project Manager...

Evans Blue Dye: A Revisit of Its Applications in Biomedicine.

Science.gov (United States)

Yao, Linpeng; Xue, Xing; Yu, Peipei; Ni, Yicheng; Chen, Feng

2018-01-01

Evans blue (EB) dye has owned a long history as a biological dye and diagnostic agent since its first staining application by Herbert McLean Evans in 1914. Due to its high water solubility and slow excretion, as well as its tight binding to serum albumin, EB has been widely used in biomedicine, including its use in estimating blood volume and vascular permeability, detecting lymph nodes, and localizing the tumor lesions. Recently, a series of EB derivatives have been labeled with PET isotopes and can be used as theranostics with a broad potential due to their improved half-life in the blood and reduced release. Some of EB derivatives have even been used in translational applications in clinics. In addition, a novel necrosis-avid feature of EB has recently been reported in some preclinical animal studies. Given all these interesting and important advances in EB study, a comprehensive revisiting of EB has been made in its biomedical applications in the review.

Effectiveness of cyclosporine and mycophenolate mofetil in a child with refractory evans syndrome

Directory of Open Access Journals (Sweden)

Piero Farruggia

2011-05-01

Full Text Available Evans Syndrome is a rare autoimmune disease consisting of hemolytic anemia, thrombocytopenia and/or neutropenia. It may be associated with other autoimmune or lymphoproliferative diseases. Its course can be extremely serious and, rarely, even life-threatening; thus it represents a excellent treatment challenge for the pediatric hematologist. First line treatment consists of steroids and/or immunoglobulin; further therapy with rituximab, vincristine, cyclophosphamide and other immunosuppressive drugs can be considered in unresponsive patients. We describe a baby with refractory Evans Syndrome that was cured by prolonged administration of mycophenolate mofetil and remained disease-free for 4 years after the discontinuation of treatment.

Enantioselective Evans-Tishchenko Reduction of b-Hydroxyketone Catalyzed by Lithium Binaphtholate

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Makoto Nakajima

2011-06-01

Full Text Available Lithium diphenylbinaphtholate catalyzed the enantioselective Evans-Tishchenko reduction of achiral b-hydroxyketones to afford monoacyl-protected 1,3-diols with high stereoselectivities. In the reaction of racemic b-hydroxyketones, kinetic optical resolution occurred in a highly stereoselective manner.

Diplodia natalensis , Pole Evans: a causal agent of citrus gummosis ...

African Journals Online (AJOL)

Isolations were made from the barks of gummosis-infected citrus trees from orchards of the University of Ghana Agricultural Research Station at Kade. The isolation media used were 1.5% water agar, 1.5% water agar + nystatin and 1.5% water agar + benomyl. Four isolates including Diplodia natalensis Pole Evans, ...

Henri Cartier-Bresson / Walker Evans : Photographier l’Amérique (1929-1947

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François Brunet

2009-08-01

Full Text Available Dans un mot adressé en 2001 à Peter Galassi, conservateur de la photographie au MOMA, Henri Cartier-Bresson, alors âgé de quatre-vingt-treize ans, écrivait plaisamment — mais non pas complaisamment : « If it had not been for the challenge of the work of Walker Evans, I don’t think I would have remained a fotographer » (« sans le défi constitué par le travail de Walker Evans, je ne crois pas que je serais resté fotographe ». Pour fêter le centenaire de Cartier-Bresson, c’est ce défi — plutôt ...

Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

CERN Document Server

Maximilien Brice

2011-01-01

Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

Posthumous Pardons, the Home Office and the Timothy Evans Case

OpenAIRE

Rubin, Gerry

2007-01-01

Examines the legal issues surrounding the exercise of the prerogative of mercy to grant posthumous pardons either to those convicted of a capital offence or those executed for offences under military law, specifically during the First World War. Focuses on the policy considerations leading to the Home Secretary’s decision to recommend the grant of a posthumous pardon for Timothy Evans in 1966.

Monotypic no longer: a new species of Panca Evans (Lepidoptera: Hesperiidae: Hesperiinae: Moncini) from South America.

Science.gov (United States)

Dolibaina, Diego Rodrigo; Carneiro, Eduardo; Mielke, Olaf Hermann Hendrik; Casagrande, Mirna Martins; Lamas, Gerardo

2017-05-19

A new species belonging to the previously monotypic genus Panca Evans, 1955, P. moseri Dolibaina, Carneiro & O. Mielke sp. nov., from grasslands areas of Peru, Bolivia and Brazil is described. Adults and male and female genitalia of the new species are illustrated, described in detail, and compared with the type species of the genus, Lerodea subpunctuli Hayward, 1934, and with its externally most similar and sympatric species, Vidius mictra Evans, 1955. The systematic position of the genus Panca and its association with lowland open natural habitats of South America are discussed.

Spectral Analysis and Dirichlet Forms on Barlow-Evans Fractals

OpenAIRE

Steinhurst, Benjamin; Teplyaev, Alexander

2012-01-01

We show that if a Barlow-Evans Markov process on a vermiculated space is symmetric, then one can study the spectral properties of the corresponding Laplacian using projective limits. For some examples, such as the Laakso spaces and a Spierpinski P\\^ate \\`a Choux, one can develop a complete spectral theory, including the eigenfunction expansions that are analogous to Fourier series. Also, one can construct connected fractal spaces isospectral to the fractal strings of Lapidus and van Frankenhu...

Public Lecture | The long road to the LHC | Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni | 9 October

CERN Document Server

2014-01-01

“The long road to the LHC” by Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni. Thursday 9 October, 7.30 p.m. in the Globe of Science and Innovation. Talk in English with simultaneous interpreting into French.  Entrance free. Limited number of seats. Reservation essential: +41 22 767 76 76 or cern.reception@cern.ch   Lyn Evans. Lecture by Lyn Evans Abstract The key to the discovery of the Higgs boson has been the development of particle accelerators at CERN over the years. I will explain how a particle accelerator works and will follow the path from the construction of the Proton Synchrotron in the 1950s to the world’s most powerful colliding beam machine, the Large Hadron Collider. Biography Born in 1945, Lyn Evans has spent his whole career in the field of high energy physics and particle accelerators, participating in all the great projects of CERN. From 1993 he led the team that designed, built and commissioned the LHC. He is currently ...

Recenzja książki: James Evans, The history and practice of ancient astronomy, Oford University Press, 1998.

OpenAIRE

Dylewski, Jarosław

2011-01-01

Professor James Evans is a physicist working an University of Pudget Sound in the USA. His reseatch is focused on ancient astronomy and application of that knowledge. He also successfully attempted to build gnomon, astrolabe or analemna – instruments used in antuiquity and medieval times to make observations of celestial bodies. In his work, The History and Practice of Ancient Astronomy, professor Evans introduces the reader to the evolution of astronomical knowledge, from the simplest observ...

Joint reproductive autonomy: does Evans v Amicus Healthcare Ltd provide for a gender-neutral approach to assisted reproductive rights?

Science.gov (United States)

Allin, Michael J

2015-06-01

Assisted reproductive technology encompasses methods of achieving pregnancy by artificial or partially artificial means. Whilst these methods are more commonly used by couples suffering from problems of infertility, some forms of assistance are employed by fertile couples, for example pre-implantation genetic diagnosis. The overall regulatory framework in the UK is predominantly found in the Human Fertilisation and Embryology Act 1990. The usual rules relating to consent and autonomy apply and were discussed in depth in Evans v Amicus Healthcare Ltd and later in Evans v United Kingdom. This paper considers whether the Evans litigation envisages the possibility of further encouraging joint autonomy in the use of zygotes and whether there is a continuing right to autonomy by the party not bearing the pregnancy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Evans Syndrome Complicated by Intratubular Hemoglobin Cast Nephropathy

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Iván González

2017-01-01

Full Text Available Evans syndrome (ES is a rare autoimmune disorder whose exact pathophysiology is unknown. It is characterized by the simultaneous or subsequent development of autoimmune hemolytic anemia (AIHA and immune thrombocytopenia (ITP. Intravascular hemolysis, with hemoglobinemia, is known to produce acute kidney injury; however, the development of intratubular hemoglobin casts (hemoglobin cast nephropathy in the setting of acute hemolysis is uncommon. Likewise, the association of ES and acute renal failure is equally uncommon. We present a case of a 7-year-old girl with ES who developed acute kidney injury in the setting of intravascular hemolysis and had widespread intratubular hemoglobin casts.

Foam separation of Rhodamine-G and Evans Blue using a simple separatory bottle system.

Science.gov (United States)

Dasarathy, Dhweeja; Ito, Yoichiro

2017-09-29

A simple separatory glass bottle was used to improve separation effectiveness and cost efficiency while simultaneously creating a simpler system for separating biological compounds. Additionally, it was important to develop a scalable separation method so this would be applicable to both analytical and preparative separations. Compared to conventional foam separation methods, this method easily forms stable dry foam which ensures high purity of yielded fractions. A negatively charged surfactant, sodium dodecyl sulfate (SDS), was used as the ligand to carry a positively charged Rhodamine-G, leaving a negatively charged Evans Blue in the bottle. The performance of the separatory bottle was tested for separating Rhodamine-G from Evans Blue with sample sizes ranged from 1 to 12mg in preparative separations and 1-20μg in analytical separations under optimum conditions. These conditions including N 2 gas pressure, spinning speed of contents with a magnetic stirrer, concentration of the ligand, volume of the solvent, and concentration of the sample, were all modified and optimized. Based on the calculations at their peak absorbances, Rhodamine-G and Evans Blue were efficiently separated in times ranging from 1h to 3h, depending on sample volume. Optimal conditions were found to be 60psi N 2 pressure and 2mM SDS for the affinity ligand. This novel separation method will allow for rapid separation of biological compounds while simultaneously being scalable and cost effective. Published by Elsevier B.V.

Katayama fever in scuba divers - A report of 3 cases | Evans | South ...

African Journals Online (AJOL)

Katayama fever in scuba divers - A report of 3 cases. A.C. Evans, D.J. Martin, B.D. Ginsburg. Abstract. Katayama fever or acute schistosomiasis probably occurs more commonly than is recorded. Interviews with a 3-man scuba diving team who had had contact with a large dam in an ·endemic area of the eastern Transvaal ...

Sotsiaalne ettevõtlus lahendab murekohti / Mervi Raudsaar, Roger Evans ; intervjueerinud Merilyn Merisalu

Index Scriptorium Estoniae

Raudsaar, Mervi, 1975-

2012-01-01

TÜ ettevõtluskeskuse kaasabil loetakse kevadsemestril Tartu ülikoolis, Eesti maaülikoolis, Tallinna ülikoolis ja EBS-is inglise- ja eestikeelset õppeainet "Sotsiaalse ettevõtluse alused". Loenguid loevad TÜ majandusteaduskonna ettevõtluse assistent Mervi Raudsaar, külalisprofessor Roger Evans Šotimaalt ning Margarita Sokolova Heateo Sihtasutusest. Ainekursus valmib koostöös Heateo Sihtasutuse ja EASiga

Chemoselective N-arylation of aminobenzamides via copper catalysed Chan-Evans-Lam reactions.

Science.gov (United States)

Liu, Shuai; Zu, Weisai; Zhang, Jinli; Xu, Liang

2017-11-15

Chemoselective N-arylation of unprotected aminobenzamides was achieved via Cu-catalysed Chan-Evans-Lam cross-coupling with aryl boronic acids for the first time. Simple copper catalysts enable the selective arylation of amino groups in ortho/meta/para-aminobenzamides under open-flask conditions. The reactions were scalable and compatible with a wide range of functional groups.

Comparative Outcomes Between Step-Cut Lengthening Calcaneal Osteotomy vs Traditional Evans Osteotomy for Stage IIB Adult-Acquired Flatfoot Deformity.

Science.gov (United States)

Saunders, Stuart M; Ellis, Scott J; Demetracopoulos, Constantine A; Marinescu, Anca; Burkett, Jayme; Deland, Jonathan T

2018-01-01

The forefoot abduction component of the flexible adult-acquired flatfoot can be addressed with lengthening of the anterior process of the calcaneus. We hypothesized that the step-cut lengthening calcaneal osteotomy (SLCO) would decrease the incidence of nonunion, lead to improvement in clinical outcome scores, and have a faster time to healing compared with the traditional Evans osteotomy. We retrospectively reviewed 111 patients (143 total feet: 65 Evans, 78 SLCO) undergoing stage IIB reconstruction followed clinically for at least 2 years. Preoperative and postoperative radiographs were analyzed for the amount of deformity correction. Computed tomography (CT) was used to analyze osteotomy healing. The Foot and Ankle Outcome Scores (FAOS) and lateral pain surveys were used to assess clinical outcomes. Mann-Whitney U tests were used to assess nonnormally distributed data while χ 2 and Fisher exact tests were used to analyze categorical variables (α = 0.05 significant). The Evans group used a larger graft size ( P lengthening. Level III, retrospective cohort study.

Comprehensive behavioural analysis of Long Evans and Sprague-Dawley rats reveals differential effects of housing conditions on tests relevant to neuropsychiatric disorders.

Directory of Open Access Journals (Sweden)

Karly M Turner

Full Text Available Genetic (G and environmental (E manipulations are known to alter behavioural outcomes in rodents, however many animal models of neuropsychiatric disorders only use a restricted selection of strain and housing conditions. The aim of this study was to examine GxE interactions comparing two outbred rat strains, which were housed in either standard or enriched cages. The strains selected were the albino Sprague-Dawley rat, commonly used for animal models, and the other was the pigmented Long Evans rat, which is frequently used in cognitive studies. Rats were assessed using a comprehensive behavioural test battery and included well-established tests frequently employed to examine animal models of neuropsychiatric diseases, measuring aspects of anxiety, exploration, sensorimotor gating and cognition. Selective strain and housing effects were observed on a number of tests. These included increased locomotion and reduced pre-pulse inhibition in Long Evans rats compared to Sprague Dawley rats; and rats housed in enriched cages had reduced anxiety-like behaviour compared to standard housed rats. Long Evans rats required fewer sessions than Sprague Dawley rats to learn operant tasks, including a signal detection task and reversal learning. Furthermore, Long Evans rats housed in enriched cages acquired simple operant tasks faster than standard housed Long Evans rats. Cognitive phenotypes in animal models of neuropsychiatric disorders would benefit from using strain and housing conditions where there is greater potential for both enhancement and deficits in performance.

S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism

OpenAIRE

Takemura, Shigekazu; Minamiyama, Yukiko; Kodai, Shintaro; Shinkawa, Hiroji; Tsukioka, Takuma; Okada, Shigeru; Azuma, Hideki; Kubo, Shoji

2013-01-01

It is important to prevent and improve diabetes mellitus and its complications in a safe and low-cost manner. S-Allyl cysteine, an aged garlic extract with antioxidant activity, was investigated to determine whether S-allyl cysteine can improve type 2 diabetes in Otsuka Long-Evans Tokushima Fatty rats with nonalcoholic fatty liver disease. Male Otsuka Long-Evans Tokushima Fatty rats and age-matched Long-Evans Tokushima Otsuka rats were used and were divided into two groups at 29 weeks of age....

Measurement of the increase in the capillary permeability in skin with Evans blue labelled with iodine-125 or 131

International Nuclear Information System (INIS)

Sugarava, S.; Goncalves, J.M.

1976-01-01

The quantitative evaluation of bradykinin and histamine with Evans blue labelled with iodine -125 or 131 is described. The activity upon vascular permeability was performed in the abdominal wall of rats injecting intravenously solution of labelled Evans blue and 0,1 ml of vasoactive drugs solution intradermally. Skin discs were cut with circular punch for external counting, quantitative results being compared with control discs. By using this method, satisfactory log dose-reponse curves were obtained for bradykinin and histamine that followed the general trend of S - shaped curves [pt

On the behavior of Brønsted-Evans-Polanyi relations for transition metal oxides

DEFF Research Database (Denmark)

Vojvodic, Aleksandra; Vallejo, Federico Calle; Guo, Wei

2011-01-01

Versatile Brønsted-Evans-Polanyi (BEP) relations are found from density functional theory for a wide range of transition metal oxides including rutiles and perovskites. For oxides, the relation depends on the type of oxide, the active site, and the dissociating molecule. The slope of the BEP...

Autoimmune hemolytic anemia, as part of Evans' syndrome, caused by cold reactive IgG autoantibodies

NARCIS (Netherlands)

Jaarsma, AS; Muis, N; DeGraaf, SSN

1996-01-01

We describe a boy with Evans' syndrome, consisting of immune thrombocytopenic purpura at age 2 and autoimmune hemolytic anemia (AIHA) at age 4. AIHA was caused by cold Ige autoantibodies. This is unusual because AIHA is generally associated with either warm IgG antibodies or cold IgM antibodies.

Plasma volume methodology: Evans blue, hemoglobin-hematocrit, and mass density transformations

Science.gov (United States)

Greenleaf, J. E.; Hinghofer-Szalkay, H.

1985-01-01

Methods for measuring absolute levels and changes in plasma volume are presented along with derivations of pertinent equations. Reduction in variability of the Evans blue dye dilution technique using chromatographic column purification suggests that the day-to-day variability in the plasma volume in humans is less than + or - 20 m1. Mass density determination using the mechanical-oscillator technique provides a method for measuring vascular fluid shifts continuously for assessing the density of the filtrate, and for quantifying movements of protein across microvascular walls. Equations for the calculation of volume and density of shifted fluid are presented.

76 FR 7832 - Evans Solutions, LLC; Notice of Declaration of Intention and Soliciting Comments, Protests, and...

Science.gov (United States)

2011-02-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. DI10-20-000] Evans Solutions... original and seven copies should be filed with: Secretary, Federal Energy Regulatory Commission, 888 First...-acre man-made lake; (2) a powerhouse containing two 5-MW turbines and twelve 5-MW generators; (3) a...

Only One? The Default Interventionist Perspective as a Unimodel-Commentary on Evans & Stanovich (2013).

Science.gov (United States)

Kruglanski, Arie W

2013-05-01

Evans and Stanovich (2013, this issue) defend the dual-processing theories of higher cognition after first criticizing them on fundamental grounds. To make that possible, they resurrect the very distinctions between the two alleged "types" of processing that they formerly had rejected. At the end, however, the default-interventionist model they embrace, seems similar to the single-process unimodel they contest. © The Author(s) 2013.

Procedure for obtaining visas for Switzerland and France - signature rights

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HR Department

2009-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d’accueil. Kirsti ASPOLA Oliver BRÜNING Inger CARRIERO Michelle CONNOR Lyndon EVANS Nathalie GRUB David JACOBS Tadeusz KURTYKA Jean-Pol MATHEYS Catherine NEDERMAN Chris ONIONS Connie POTTER Jeanne ROSTANT Ulla TIHINEN Emmanuel TSESMELIS Rüdiger VOSS The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), "the Organization shall not request any legitimisat...

Man’s Place in Nature. The Biocentrism of Zdzisława Piatek vs. the Anthropology of Tadeusz Ślipko and Piotr Mazur

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Paulina Łośko

2015-06-01

Full Text Available Man’s Place in Nature. The Biocentrism of Zdzisława Piatek vs. the Anthropology of Tadeusz Ślipko and Piotr MazurThis article concerns the issue of human beings’ role and purpose in nature, taking as its central example the biocentric conception developed by Zdzislawa Piatek. Man’s relation to his natural environment is an extremely important one. Our habitat shapes our lives and allows civilization to progress, yet life and progress can themselves pose a threat to the environment. It is for this reason that ecological matters have attracted such attention amongst a variety of specialists over the last few decades – not only from those working in the field of the natural sciences, but also from philosophers, in that the threat of ecological crisis has emerged in connection with civilizational advancement. The goal of this article is to give an adequate account of the place of human beings in this system. By an “adequate account”, I mean one that defines the place and purpose of humans within their habitat in terms that allow for a consideration of spiritual, physical and moral aspects of human nature. With this ultimate aim in mind, the first part of the article presents the biocentric conception of Piatek. Following on from this, the author considers the theocentric philosophy of Slipko and classical anthropology as construed by Mazur – both of which are opposed to biocentric philosophy. The final part then presents the author’s own conclusions.

Moniliophthora roreri (Cif y Par) Evans et al. en el cultivo de cacao

OpenAIRE

Sánchez Mora, Fernando David; Garcés Fiallos, Felipe Rafael

2012-01-01

More than a century, cacao (Theobroma cacao L.) in Ecuador has been an important source of income for farmers and currency for the country, becoming one of the biggest exporters worldwide. Then, gradually lost that status due to the attack of diseases, including moniliasis caused by [Moniliophthora roreri (Cif and Par) Evans et al.]. It can cause damage of up to 80% in production. Currently there is little scientific date information on its occurrence, symptoms, etiology, epidemiology, life c...

Partial splenic embolization combined with vincristine infusion for the treatment of refractory idiopathic thrombocytopenic purpura and Evans syndrome: observation of its long-term efficacy

International Nuclear Information System (INIS)

Chen Shibing

2011-01-01

Objective: To observe the long-term efficacy of partial spleen embolization combined with vincristine infusion in treating refractory idiopathic thrombocytopenic purpura (ITP) and Evans syndrome. Methods: During the period of 2000-2007, partial spleen embolization together with vincristine infusion was carried out in 30 patients with refractory idiopathic thrombocytopenic purpura (n=24) or Evans syndrome (n=6). Vincristine infusion (2 mg) via splenic artery was performed before partial spleen embolization procedure. The long-term effectiveness was observed and analyzed. Results: One week after the treatment, the platelet count was increased from preoperative (10.23±8.28) × 10 9 /L to (140.28±85.45) × 10 9 /L in patients with ITP, while the platelet count was increased from preoperative (12±8) × 10 9 /L to (210±60) × 10 9 /L in patients with Evans syndrome. Meanwhile, the hemoglobin level showed an increase in different degrees, from preoperative (63.00±13.62) g/L to postoperative (123.00±13.14) g/L. The therapeutic effectiveness was 100%. During the follow-up time lasting for 3-5 years, recurrence was seen in 11 patients (36.7%) and the overall efficacy rate was 63.3%. Conclusion: For the treatment of refractory idiopathic thrombocytopenic purpura and Evans syndrome, partial spleen embolization combined with vincristine infusion carries reliable long-term efficacy. (author)

Cyberbullying among children and adolescents – an overview on epidemiological studies and effective preventive programs

OpenAIRE

Capurso, Silva; Paradžik, Ljubica; Čale Mratović, Matija

2017-01-01

Bullying is defined as repeated aggressive behavior (Kowalski & Limber, 2007; Olweus, 1993, and as such has been recognized as a significant social issue. Furthermore, we know that the incidence of bullying behaviors increases with the students’ age (Cassidy, Jackson & Brown, 2009; Green-Forde, 2014; Kowalski & Limber, 2007). Cyber bullying, electronic/ online bullying, or online social cruelty is, according to Kowalski & Limber (2007), a relatively new kind of bullying through email, insta...

Minimum wage effects on employment and school enrollment: reply to Evans and Turner

OpenAIRE

David Neumark; William L. Wascher

1996-01-01

In earlier work, we presented results suggesting that minimum wage increases have important consequences for both the employment opportunities of youths and their decision to enroll in school. In this paper, we show that the recent claim made by William Evans and Mark Turner that our results are sensitive to changes in the definition of the enrollment rate is based upon an analysis that uses a mismeasured minimum wage index. When the data are constructed properly, our original conclusions are...

Sulfonato-imino copper(ii) complexes: fast and general Chan-Evans-Lam coupling of amines and anilines.

Science.gov (United States)

Hardouin Duparc, V; Schaper, F

2017-10-14

Sulfonato-imine copper complexes with either chloride or triflate counteranions were prepared in a one-step reaction followed by anion-exchange. They are highly active in Chan-Evans-Lam couplings under mild conditions with a variety of amines or anilines, in particular with sterically hindered substrates. No optimization of reaction conditions other than time and/or temperature is required.

Strain-dependent effects of acute caffeine on anxiety-related behavior in PVG/c, Long-Evans and Wistar rats.

Science.gov (United States)

Hughes, Robert N; Hancock, Nicola J

2016-01-01

To assess the possibility that acute caffeine's behavioral action might depend on rats' strain, effects of 50mg/kg of the drug were observed on activity, anxiety-related behavior and habituation learning in male and female rats from three different strains, namely PVG/c, Long-Evans and Wistar. All subjects were tested in an open field, an elevated plus maze and a light-dark box. For the three strains combined, increased occupancy of the center of the open field and entries of the open plus-maze arms with caffeine suggested caffeine-induced anxiolysis, whereas increased grooming in the open field, decreased rearing in the plus maze and increased risk assessment in the light-dark box were consistent with anxiogenesis. Caffeine also reduced open-field rearing only for PVG/c rats, and entries into and occupation of the light side of the light-dark box only for Long-Evans rats, and increased total defecation in the three types of apparatus for all three strains combined. Overall, caffeine appeared to be mainly anxiogenic. The drug also increased open-field ambulation for PVG/c rats and walking for all rats, but decreased open-field ambulation and entries into the plus maze closed arms for Wistar rats alone. In general, Wistar rats appeared to be the least and Long-Evans the most anxious of the three strains investigated. Caffeine also decreased within-session habituation of open-field ambulation for PVG/c rats alone, thereby suggesting strain-dependent interference with non-associative learning and short-term memory. Several overall sex differences were also observed that supported female rats being more active and less anxious than males. Copyright © 2015 Elsevier Inc. All rights reserved.

Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats

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Lee Jung Eun

2012-09-01

Full Text Available Abstract Background Hyperglycemia leads to cardiac oxidative stress and an imbalance in glucose homeostasis. Diabetic cardiomyopathy is characterised by cardiac hypertrophy and fibrosis. However, the underlying mechanisms of diabetic cardiomyopathy are not fully understood. This study aimed to investigate the effects of alpha-lipoic acid (ALA on cardiac energy metabolism, antioxidant effect, and fibrosis in the hearts of Otsuka Long-Evans Tokushima fatty (OLETF rats. Methods Animals were separated into non-diabetic Long-Evans Tokushima Otsuka (LETO rats and diabetes-prone OLETF rats with or without ALA (200 mg/kg/day administration for 16 weeks. Diabetic cardiomyopathy was assessed by staining with Sirius Red. The effect of ALA on AMPK signalling, antioxidant enzymes, and fibrosis-related genes in the heart of OLETF rats were performed by Western blot analysis or immunohistochemistry. Results Western blot analysis showed that cardiac adenosine monophosphate-activated kinase (AMPK signalling was lower in OLETF rats than in LETO rats, and that ALA treatment increased the signalling in OLETF rats. Furthermore, the low antioxidant activity in OLETF rats was increased by ALA treatment. In addition to increased Sirius red staining of collagen deposits, transforming growth factor-β1 (TGF-β1 and connective tissue growth factor (CTGF were expressed at higher levels in OLETF rat hearts than in LETO rat hearts, and the levels of these factors were decreased by ALA. Conclusions ALA enhances AMPK signalling, antioxidant, and antifibrogenic effect. Theses findings suggest that ALA may have beneficial effects in the treatment of diabetic cardiomyopathy.

Genetic recombination at the human RH locus: A family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene

Energy Technology Data Exchange (ETDEWEB)

Huang, C.H.; Chen, Y.; Reid, M. [Lindsley F. Kimball Research Inst., New York, NY (United States); Ghosh, S.

1996-10-01

The human RH locus appears to consist of two structural genes, D and CE, which map on the short arm p34-36 of chromosome 1 and specify a most complex system of blood-group genetic polymorphisms. Here we describe a family study of the Evans (also known as {open_quotes}D..{open_quotes}) phenotype, a codominant trait associated with both qualitative and quantitative changes in D-antigen expression. A cataract-causing mutation was also inherited in this family and was apparently cotransmitted with Evans, suggesting a chromosomal linkage of these two otherwise unrelated traits. Southern blot analysis and allele-specific PCR showed the linkage of Evans with a SphI RFLP marker and the presence of a hybrid gene in the RH locus. To delineate the pattern of gene expression, the composition and structure of Rh-polypeptide transcripts were characterized by reverse transcriptase-PCR and nucleotide sequencing. This resulted in the identification of a novel Rh transcript expressed only in the Evans-positive erythroid cells. Sequence analysis showed that the transcript maintained a normal open reading frame but occurred as a CE-D-CE composite in which exons 2-6 of the CE gene were replaced by the homologous counterpart of the D gene. This hybrid gene was predicted to encode a CE-D-CE fusion protein whose surface expression correlates with the Evans phenotype. The mode and consequence of such a recombination event suggest the occurrence, in the RH locus, of a segmental DNA transfer via the mechanism of gene conversion. 31 refs., 6 figs., 1 tab.

Neonatal familial Evans syndrome associated with joint hypermobility and mitral valve regurgitation in three siblings in a Saudi Arab family

International Nuclear Information System (INIS)

Ahmed, Fathelrahman E.; AlBakrah, Mohameed S.

2009-01-01

The occurrence of autoimmune hemolytic anemia and immune thrombocytopenia in the absence of a known underlying cause led to the diagnosis of Evans syndrome in a 9 month old male. Subsequently, a similar diagnosis was made in two siblings (a 3 year old boy and a 1 day old girl). The 9 month old had a chronic course with exacerbations. He was treated with steroids, intravenous immunoglobulin and colchiccine with a variable response. He died of congestive heart failure at the age of 8 years. The brother's disease course was one of remission and exacerbation. With time, remissions were prolonged and paralleled an improvement in joint hypermobility. The sister died of sepsis after a chronic course with severe exacerbattions. Only two families with Evans syndrome have been reported in the English medical literature. In one report (in a Saudi Arab family), the disease was associated with hereditary spastic paraplegia. (author)

Loe lisaks / Anthony de Kowalsky

Index Scriptorium Estoniae

Kowalsky, Anthony de

2008-01-01

Lühiarvustused : Mark Ravenhilli "Võta mind!" Vanemuises, lavastaja Ingomar Vihmar Tartu Sadamateatris; näitleja Kristjan Sarve aktsioon "99x" Henry Milleri "Vähi pöörijoonest", mida näitleja esitab 99 korda ja Eesti teatri parima meesnäitleja auhinnaga pärjatud Üllar Saaremäe nimirollist lavastuses "Cyrano de Bergerac" Rakvere Teatris

Eesti naksitrallid Poolas / Flavek Kowalsky

Index Scriptorium Estoniae

Kowalsky, Flavek

2000-01-01

8. märtsist Sopoti galeriis "Marzenie Provincionalnej Dziewczyny" ("Provintsitüdruku Unistus") samanimelise näitusesarja näitus "Provintsipoisi unistus". Kuraator Paulina M. Olowska. Eestlaste Jasper Zoova, Tarrvi Laamannni ja Kiwa töödest. Kunstiväljapanekule sekundeerinud muusikaõhtul klubis "Sfinks" esinesid T. Laamannn ja Kiwa pop-projektiga "Nervous cowboys".

Separation of Evans and Hiro currents in VDE of tokamak plasma

Science.gov (United States)

Galkin, Sergei A.; Svidzinski, V. A.; Zakharov, L. E.

2014-10-01

Progress on the Disruption Simulation Code (DSC-3D) development and benchmarking will be presented. The DSC-3D is one-fluid nonlinear time-dependent MHD code, which utilizes fully 3D toroidal geometry for the first wall, pure vacuum and plasma itself, with adaptation to the moving plasma boundary and accurate resolution of the plasma surface current. Suppression of fast magnetosonic scale by the plasma inertia neglecting will be demonstrated. Due to code adaptive nature, self-consistent plasma surface current modeling during non-linear dynamics of the Vertical Displacement Event (VDE) is accurately provided. Separation of the plasma surface current on Evans and Hiro currents during simulation of fully developed VDE, then the plasma touches in-vessel tiles, will be discussed. Work is supported by the US DOE SBIR Grant # DE-SC0004487.

Moniliophthora roreri (Cif y Par Evans et al. in the crop of cocoa

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Fernando David Sánchez Mora

2012-09-01

Full Text Available More than a century, cacao (Theobroma cacao L. in Ecuador has been an important source of income for farmers and currency for the country, becoming one of the biggest exporters worldwide. Then, gradually lost that status due to the attack of diseases, including moniliasis caused by [Moniliophthora roreri (Cif and Par Evans et al.]. It can cause damage of up to 80% in production. Currently there is little scientific date information on its occurrence, symptoms, etiology, epidemiology, life cycle management or control strategies of that disease, by performing this review both these important topics, bringing with it to this area of knowledge.

Mozart K.448 attenuates spontaneous absence seizure and related high-voltage rhythmic spike discharges in Long Evans rats.

Science.gov (United States)

Lin, Lung-Chang; Juan, Chun-Ting; Chang, Hsueh-Wen; Chiang, Ching-Tai; Wei, Ruey-Chang; Lee, Mei-Wen; Mok, Hin-Kiu; Yang, Rei-Cheng

2013-05-01

Recent research has revealed more evidence supporting the positive effects of music on humans and animals. However, evidence of music's effects on improving epilepsy in animals is sparse. This study aimed to clarify the influence of Mozart's music in Long Evans rats, which are characterized by spontaneous absence epilepsy (SAE) and high-voltage rhythmic spike (HVRS) discharges. Continuous electroencephalograms comprised of HVRS discharges, and behavioral performance were recorded in Long Evans rats (n=5) before, during, and after exposure to the Mozart's Sonata for Two Pianos in D Major, K.448 (Mozart K.448). The same evaluation was repeated after they had been subjected to daily exposure of the music for 20 days. Seizure frequencies and spontaneous HVRS discharges were reduced in all of the SAE rats during and after music exposure compared with the pre-music stage. The average seizure frequencies were 79.8±24.6, 48±15.2, and 33±12.1/h before, during, and after music exposure, respectively. The average run of spike episodes were 84.6±18.4, 52±17.8, and 36.8±16.9/h before, during, and after music exposure, respectively. The seizure frequencies and related run of spike episodes decreased by 39.8% and 38.5% during, and 58.6% and 56.6% post music exposure, respectively. The average run of spike durations and spike numbers also showed significant decreases (reduction by 47.1%, 47.8% during music and 60.8%, 61.3% post music). After daily music exposure for 20 days, the number of HVRS discharges and seizure frequencies during and after music exposure, however, showed no further accumulative reduction or adaptation effect. These results suggest that Mozart K.448 had a positive short-term effect in attenuating the spontaneous HVRS discharges in Long Evans rats. However, the mechanism needs further investigation. Copyright © 2013 Elsevier B.V. All rights reserved.

Hydrology, microbiology and carbon cycling at a high Arctic polythermal glacier, (John Evans Glacier, Ellesmere Island, Canada)

Science.gov (United States)

Skidmore, Mark Leslie

Analysis of the hydrology, hydrochemistry and microbiology at polythermal John Evans Glacier and geochemical and isotopic data from Haut Glacier d'Arolla demonstrates that certain subglacial chemical weathering processes are microbially mediated. Subglacial drainage is likely an annual occurrence beneath John Evans Glacier and solute rich subglacial waters indicate over winter storage at the glacier bed. Subglacial microbial populations are also present, and are viable under simulated near in situ conditions at 0.3°C. This suggests that temperate subglacial environments at a polythermal glacier, which are isolated by cold ice above and around them, provide a viable habitat for life where basal water and organic carbon are present throughout the year. Thus, a subglacial microbial ecosystem based upon legacy carbon, (from old soils or surface inputs) rather than primary production may exist, where redox processes are a key component, and seasonal anoxia may occur. The existence of anoxic environments is supported by the presence of strictly anaerobic bacteria (sulphate reducing bacteria and methanogens) in the basal sediments---which are viable in culture at 4°C---and also argues that these bacteria are not washed in with oxygenated surface meltwaters, but are present in the subglacial environment. During the summer meltseason there is a large input of surficial waters to the subglacial system and water residence times are drastically reduced. Hence, kinetic weathering processes dominate, resulting in light delta 13C-DIC (dissolved inorganic carbon) in glacial runoff, as verified by experimental work on CaCO3 and John Evans Glacier sediments. The experiments demonstrate kinetic bedrock fractionation (KBF) during carbonate hydrolysis and that kinetic fractionation of CO2 (KFC) is proportional to the rate of CO2 draw down during the carbonation of carbonates. This results in significantly depleted delta13C-DIC values (≤-16 ‰) relative to the bedrock carbonate

We favor formal models of heuristics rather than lists of loose dichotomies: a reply to Evans and Over

Science.gov (United States)

Gigerenzer, Gerd

2009-01-01

In their comment on Marewski et al. (good judgments do not require complex cognition, 2009) Evans and Over (heuristic thinking and human intelligence: a commentary on Marewski, Gaissmaier and Gigerenzer, 2009) conjectured that heuristics can often lead to biases and are not error free. This is a most surprising critique. The computational models of heuristics we have tested allow for quantitative predictions of how many errors a given heuristic will make, and we and others have measured the amount of error by analysis, computer simulation, and experiment. This is clear progress over simply giving heuristics labels, such as availability, that do not allow for quantitative comparisons of errors. Evans and Over argue that the reason people rely on heuristics is the accuracy-effort trade-off. However, the comparison between heuristics and more effortful strategies, such as multiple regression, has shown that there are many situations in which a heuristic is more accurate with less effort. Finally, we do not see how the fast and frugal heuristics program could benefit from a dual-process framework unless the dual-process framework is made more precise. Instead, the dual-process framework could benefit if its two “black boxes” (Type 1 and Type 2 processes) were substituted by computational models of both heuristics and other processes. PMID:19784854

Color Terms and Color Concepts

Science.gov (United States)

Davidoff, Jules

2006-01-01

In their lead articles, both Kowalski and Zimiles (2006) and O'Hanlon and Roberson (2006) declare a general relation between color term knowledge and the ability to conceptually represent color. Kowalski and Zimiles, in particular, argue for a priority for the conceptual representation in color term acquisition. The complexities of the interaction…

Modeling Ethanol Decomposition on Transition Metals: A Combined Application of Scaling and Bronsted-Evans-Polanyi Relations

DEFF Research Database (Denmark)

Ferrin, P.; Simonetti, D.; Kandoi, S.

2009-01-01

calculations necessary to describe trends in activity and selectivity across metal and alloy surfaces, thus extending the reach of DFT to more complex systems. In-this work, the well-known family of Bronsted-Evans-Polanyi (BEP) correlations, connecting minima with maxima in the potential energy surface...... on a subset of these surfaces are calculated. Experiments on supported catalysts verify that this simple model is reasonably accurate in describing reactivity trends across metals, suggesting that the combination of BEP and scaling relations may substantially reduce the cost of DFT calculations required...

We favor formal models of heuristics rather than lists of loose dichotomies : A reply to Evans and Over

OpenAIRE

Marewski, J.; Gaissmaier, W.; Gigerenzer, G.

2010-01-01

In their comment on Marewski et al. (good judgments do not require complex cognition, 2009) Evans and Over (heuristic thinking and human intelligence: a commentary on Marewski, Gaissmaier and Gigerenzer, 2009) conjectured that heuristics can often lead to biases and are not error free. This is a most surprising critique. The computational models of heuristics we have tested allow for quantitative predictions of how many errors a given heuristic will make, and we and others have measured the a...

Evans Syndrome Presented with Marginal Zone Lymphoma and Duodenal Neuroendocrine Tumor in an Elderly Woman

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Daniele D'Ambrosio

2016-12-01

Full Text Available Evans syndrome (ES is an autoimmune disorder characterized by simultaneous or sequential development of autoimmune hemolytic anemia, immune thrombocytopenia, and/or neutropenia. ES can be classified as a primary (idiopathic or secondary (associated with an underlying disease syndrome. We report a case of ES in an elderly patient in the presence of multiple trigger factors such as recent influenza vaccine, marginal zone lymphoma, and neuroendocrine tumor G1. Whether this association is casual or causal remains a matter of speculation. It is however necessary to have a thorough work-up in a newly diagnosed ES and a more accurate search of miscellaneous factors especially in elderly patients.

Evans syndrome with non-ST segment elevation myocardial infarction complicated by hemopericardium

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Filiz Kizilirmak

2016-09-01

Full Text Available Evans syndrome (ES is a rare hematological disease characterized by autoimmune hemolytic anemia, immune thrombocytopenia, and/or neutropenia, all of which may be seen simultaneously or subsequently. Thrombotic events in ES are uncommon. Furthermore, non-ST segment-elevation myocardial infarction (NSTEMI during ES is a very rare condition. Here, we describe a case of a 69-year-old female patient presenting with NSTEMI and ES. Revascularization via percutaneous coronary intervention (PCI was scheduled and performed. Hemopericardium and cardiac tamponade occurred 5 h after PCI, and urgent pericardiocentesis was performed. Follow-up was uneventful, and the patient was safely discharged. Early recognition and appropriate management of NSTEMI is crucial to prevent morbidity and mortality. Coexistence of NSTEMI and ES, which is associated with increased bleeding risk, is a challenging scenario and these patients should be closely monitored in order to achieve early recognition and treatment of complications.

On the behavior of Bronsted-Evans-Polanyi Relations for Transition Metal Oxides

Energy Technology Data Exchange (ETDEWEB)

Vojvodic, Aleksandra

2011-08-22

Versatile Broensted-Evans-Polanyi (BEP) relations are found from density functional theory for a wide range of transition metal oxides including rutiles and perovskites. For oxides, the relation depends on the type of oxide, the active site and the dissociating molecule. The slope of the BEP relation is strongly coupled to the adsorbate geometry in the transition state. If it is final state-like the dissociative chemisorption energy can be considered as a descriptor for the dissociation. If it is initial state-like, on the other hand, the dissociative chemisorption energy is not suitable as descriptor for the dissociation. Dissociation of molecules with strong intramolecular bonds belong to the former and molecules with weak intramolecular bonds to the latter group. We show, for the prototype system La-perovskites, that there is a 'cyclic' behavior in the transition state characteristics upon change of the active transition metal of the oxide.

Changes in plasma glucose in Otsuka Long-Evans Tokushima Fatty rats after oral administration of maple syrup.

Science.gov (United States)

Nagai, Noriaki; Yamamoto, Tetsushi; Tanabe, Wataru; Ito, Yoshimasa; Kurabuchi, Satoshi; Mitamura, Kuniko; Taga, Atsushi

2015-01-01

We investigate whether maple syrup is a suitable sweetener in the management of type 2 diabetes using the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The enhancement in plasma glucose (PG) and glucose absorption in the small intestine were lower after the oral administration of maple syrup than after sucrose administration in OLETF rats, and no significant differences were observed in insulin levels. These data suggested that maple syrup might inhibit the absorption of glucose from the small intestine and preventing the enhancement of PG in OLETF rats. Therefore, maple syrup might help in the prevention of type 2 diabetes.

Logic Programming in LISP.

Science.gov (United States)

1981-01-01

Rapport, Groupe Intelligence Pasero, R., Artificielle , Universite d’Aix-Marseille, Roussel, P. Luminy, France, 1973. [Kowalski 1974] Kowalski, R. A...THIS PAGZ(Whan Doee Es tMord) Item 20 (Cont’d) ------ work in the area of artificial intelligence and those used in general program development into a...logic programming with LISP for implementing intelligent data base query systems. Continued developments will allow for enhancements to be made to the

Ocorrência simultânea de síndrome de Evans e anemia falciforme em uma criança de 2 anos Simultaneous occurrence of Evans syndrome and sickle cell anemia in a 2 year-old child

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Adriana Alexandre Brito

2012-04-01

Full Text Available A associação entre anemia falciforme (AF e síndrome de Evans (SE parece ser rara. Esse estudo objetivou relatar o caso de uma criança com AF e SE. A paciente R. M. S. S., 2 anos de idade, foi admitida em um centro hematológico apresentando hemorragia de mucosa, leucometria 20,3 × 10(9/l, hemoglobina 4,6 g/dl e plaquetas 28 × 10(9/l. Posteriormente, realizou-se mielograma, que evidenciou hipercelularidade eritroide, sugerindo hemólise. Teste positivo da antiglobulina direcionou o diagnóstico para SE. Iniciou-se pulsoterapia com corticoide até regularização da plaquetometria. Hemácias em foice foram visualizadas no esfregaço sanguíneo; eletroforese de hemoglobina revelou fenótipo SS. A associação parece ter sido fortuita e gerou quadro grave, que deve ser reconhecido prontamente.The association of sickle cell anemia (SCA and Evans syndrome (ES seems to be uncommon. This study aimed to report a case of a child with SCA and SE. 2 year-old R. M. S. S. was admitted into a hematologic center with mucosal bleedings. Exam results revealed leucocyte 20.3 × 10(9/l, hemoglobin 4.6 g/dl, and platelets 28 × 10(9/l. Subsequently, myelogram was performed and showed erythroid-hypercellularity, which suggested hemolysis. Positive antiglobulin test corroborated the diagnosis of ES. Corticosteroid pulse therapies were conducted until normalization of platelet count. Sickle cells were detected in blood smears and hemoglobin electrophoresis revealed SS phenotype. Despite the fact the association appears to occur randomly, it causes severe clinical symptoms, which must be promptly recognized.

Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; referees: 2 approved

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Sara Botschuijver

2016-01-01

Full Text Available Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS. In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift work and trans meridian flights, are associated with the prevalence of IBS. This raises the question whether disruptions of circadian control are responsible for the observed pathology in IBS. Prior to investigating altered rhythmicity in relation to visceral hypersensitivity in a rat model for IBS, it is relevant to establish whether normal rats display circadian variation similar to healthy men.  Methodology and findings: In rodents colorectal distension leads to reproducible contractions of abdominal musculature. We used quantification of this so called visceromotor response (VMR by electromyography (EMG to assess visceral sensitivity in rats. We assessed the VMR in normal male Long Evans rats at different time points of the light/dark cycle. Although a control experiment with male maternal separated rats confirmed that intentionally inflicted (i.e. stress induced changes in VMR can be detected, normal male Long Evans rats showed no variation in VMR along the light/dark cycle in response to colorectal distension. Conclusions: In the absence of a daily rhythm of colorectal sensitivity in normal control rats it is not possible to investigate possible aberrancies in our rat model for IBS.

Dermatomiositis y síndrome de evans asociado a infección por HTLV-1

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David Loja-Oropeza

2016-01-01

Full Text Available Paciente mujer de 55 años de edad, natural de Ayacucho, con antecedente de dermatomiositis desde hace 3 años, recibió tratamiento irregular con prednisona. Dos meses antes del ingreso presenta anemia hemolítica autoinmune y púrpura trombocitopénica idiopática, recibió pulsos de metilprednisolona y transfusión de paquetes globulares. Al ingreso, soporosa, mal estado general, marcada pérdida ponderal, deshidratada, livedo reticularis en miembros inferiores, onicodistrofia y onicolisis múltiple en los dedos de ambos pies. Western Blot positivo para HTLV-1. Evoluciona con hipoglicemia recurrente. Reportamos un caso de dermatomiositis y síndrome de Evans presentados en el contexto de una infección por virus linfotrópico humano tipo 1.

Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits

Science.gov (United States)

Uttl, Libor; Petrasek, Tomas; Sengul, Hilal; Svojanovska, Marketa; Lobellova, Veronika; Vales, Karel; Radostova, Dominika; Tsenov, Grygoriy; Kubova, Hana; Mikulecka, Anna; Svoboda, Jan; Stuchlik, Ales

2018-01-01

The role of NMDA receptors in learning, memory and hippocampal function has long been recognized. Post-mortem studies have indicated that the expression or subunit composition of the NMDA glutamate receptor subtype might be related to the impaired cognitive functions found in schizophrenia patients. NMDA receptor antagonists have been used to develop animal models of this disorder. There is accumulating evidence showing that not only the acute but also the chronic application of NMDA receptor antagonists may induce schizophrenia-like alterations in behavior and brain functions. However, limited evidence is available regarding the consequences of NMDA receptor blockage during periods of adolescence and early adulthood. This study tested the hypothesis that a 2-week treatment of male Long-Evans and Wistar rats with dizocilpine (MK-801; 0.5 mg/kg daily) starting at postnatal days (PD) 30 and 60 would cause a long-term cognitive deficit and changes in the levels of NMDA receptor subunits. The working memory version of the Morris water maze (MWM) and active place avoidance with reversal on a rotating arena (Carousel) requiring cognitive coordination and flexibility probed cognitive functions and an elevated-plus maze (EPM) was used to measure anxiety-like behavior. The western blot method was used to determine changes in NMDA receptor subunit levels in the hippocampus. Our results showed no significant changes in behaviors in Wistar rats. Slightly elevated anxiety-like behavior was observed in the EPM in Long-Evans rats with the onset of treatment on PD 30. Furthermore, Long-Evans rats treated from PD 60 displayed impaired working memory in the MWM. There were; however, no significant changes in the levels of NMDA receptor subunits because of MK-801 administration. These findings suggest that a 2-week treatment starting on PD 60 in Long-Evans rats leads to long-term changes in working memory, but this deficit is not paralleled by changes in NMDA receptor subunits. These

Simulations of vertical disruptions with VDE code: Hiro and Evans currents

Science.gov (United States)

Li, Xujing; Di Hu Team; Leonid Zakharov Team; Galkin Team

2014-10-01

The recently created numerical code VDE for simulations of vertical instability in tokamaks is presented. The numerical scheme uses the Tokamak MHD model, where the plasma inertia is replaced by the friction force, and an adaptive grid numerical scheme. The code reproduces well the surface currents generated at the plasma boundary by the instability. Five regimes of the vertical instability are presented: (1) Vertical instability in a given plasma shaping field without a wall; (2) The same with a wall and magnetic flux ΔΨ|plX< ΔΨ|Xwall(where X corresponds to the X-point of a separatrix); (3) The same with a wall and magnetic flux ΔΨ|plX> ΔΨ|Xwall; (4) Vertical instability without a wall with a tile surface at the plasma path; (5) The same in the presence of a wall and a tile surface. The generation of negative Hiro currents along the tile surface, predicted earlier by the theory and measured on EAST in 2012, is well-reproduced by simulations. In addition, the instability generates the force-free Evans currents at the free plasma surface. The new pattern of reconnection of the plasma with the vacuum magnetic field is discovered. This work is supported by US DoE Contract No. DE-AC02-09-CH11466.

Parvovirus B19-triggered Acute Hemolytic Anemia and Thrombocytopenia in a Child with Evans Syndrome.

Science.gov (United States)

Zikidou, Panagiota; Grapsa, Anastassia; Bezirgiannidou, Zoe; Chatzimichael, Athanassios; Mantadakis, Elpis

2018-01-01

Human parvovirus B19 (HPV-B19) is the etiologic agent of erythema infectiosum, of transient aplastic crises in individuals with underlying chronic hemolytic disorders, and of chronic pure red cell aplasia in immunocompromised individuals. We describe a 14-year-old girl with long-standing Evans syndrome, who presented with severe anemia, reticulocytopenia and thrombocytopenia. A bone marrow aspirate revealed severe erythroid hypoplasia along with the presence of giant pronormoblasts, while serological studies and real-time PCR of whole blood were positive for acute parvovirus B19 infection. The patient was initially managed with corticosteroids, but both cytopenias resolved only after administration of intravenous gamma globulin 0.8g/kg. Acute parvovirus B19 infection should be suspected in patients with immunologic diseases, who present reticulocytopenic hemolytic anemia and thrombocytopenia. In this setting, intravenous gamma globulin is effective for both cytopenias.

Multiple [3H]imipramine binding sites in brains of male and female Fawn-Hooded and Long-Evans rats

International Nuclear Information System (INIS)

Ieni, J.R.; Zukin, S.R.; Praag, H.M. van; Tobach, E.; Barr, G.A.

1985-01-01

Comparisons of high- and low-affinity [ 3 H]imipramine binding to whole brain homogenates from adult male and female rats of the Fawn-Hooded and Long-Evans strains were performed. Most strikingly, no significant differences were observed between the two strains in any of the binding parameters, indicating that brain [ 3 H]imipramine binding sites, which may be related to the serotonergic uptake process, appear normal in a strain of rats with serotonin platelet storage pool disease. However, a significant sex difference in high- but not low-affinity whole brain [ 3 H]imipramine Bsub(max) values was observed, with females of both strains having higher densities than males. (Auth.)

Kinetic analysis of the rate of corneal wound healing in Otsuka long-evans Tokushima Fatty rats, a model of type 2 diabetes mellitus.

Science.gov (United States)

Nagai, Noriaki; Murao, Takatoshi; Okamoto, Norio; Ito, Yoshimasa

2010-01-01

Diabetic keratopathy is a well-known ocular complication secondary to type 2 diabetes mellitus. In this study, we performed a kinetic analysis of corneal wound healing in Long-Evans rats (normal rat) and Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type 2 diabetes mellitus. Corneal wound healing in 7-week-old normal rats was mostly complete 24 h after corneal epithelial abrasion, and the process of corneal wound healing took place according to an equation with a first-order rate constant. The rate of corneal wound healing in normal rats decreased with aging. The process of corneal wound healing in 38- and 60-week-old normal and OLETF rats occurred in two phases with rate constants for the first and second phases represented as alpha and beta, respectively. The alpha and beta values in 38- and 60-week-old OLETF rats were lower than those in normal rats of the corresponding age. Furthermore, a close relationship was observed between the corneal wound healing rate constant and plasma glucose levels in OLETF rats. The present studies suggest the sequence of events that occur following damage to the corneal surface in OLETF rats as a model animal for a human type 2 diabetes mellitus.

Association in Long-Evans hooded rats of red cell 2,3-diphosphoglycerate levels with hemoglobin types.

Science.gov (United States)

Brewer, G; Gilman, J; Noble, N; Crews, V

1978-08-01

Two sublines of commercially available Long-Evans hooded rats have been developed by genetic selection. These sublines have widely differing levels of erythrocyte 2,3-diphosphoglycerate (DPG) due to different alleles at a single genetic locus. In the present work, it is shown that rats from the commercial population are also polymorphic at a hemoglobin locus, probably involving two alleles of the IIIbeta-globin chain locus. Particular hemoglobin types have been found to be strongly associated with certain DPG types, not only in the high-DPG and low-DPG lines but also in the commercial population. Two explanations for this association are considered. One is a single-locus hypothesis, with hemoglobin allelic variation causing DPG variation, and the other is a two-locus hypothesis, with marked linkage disequilibrium.

Parvovirus B19-triggered acute hemolytic anemia and thrombocytopenia in a child with Evans syndrome

Directory of Open Access Journals (Sweden)

ELPIS MANTADAKIS

2018-03-01

Full Text Available Background: Human parvovirus B19 (HPV-B19 is the etiologic agent of erythema infectiosum, of transient aplastic crises in individuals with underlying chronic hemolytic disorders, and of chronic pure red cell aplasia in immunocompromised individuals. Case report. We describe a 14-year-old girl with long-standing Evans syndrome, who presented with severe anemia, reticulocytopenia and thromocytopenia. A bone marrow aspirate revealed severe erythroid hypoplasia along with presence of giant pronormoblasts, while serological studies and real-time PCR of whole blood were positive for acute parvovirus B19 infection. The patient was initially managed with corticosteroids, but both cytopenias resolved only after administration of intravenous gamma globulin 0.8g/kg. Conclusion: Acute parvovirus B19 infection should be suspected in patients with immunologic diseases, who present with reticulocytopenic hemolytic anemia and thrombocytopenia. In this setting, intravenous gamma globulin is effective for both cytopenias.

A Case Study: Dual-Process Theories of Higher Cognition-Commentary on Evans & Stanovich (2013).

Science.gov (United States)

Osman, Magda

2013-05-01

Dual-process theories of higher order cognition (DPTs) have been enjoying much success, particularly since Kahneman's 2002 Nobel prize address and recent book Thinking, Fast and Slow (2009). Historically, DPTs have attempted to provide a conceptual framework that helps classify and predict differences in patterns of behavior found under some circumstances and not others in a host of reasoning, judgment, and decision-making tasks. As evidence has changed and techniques for examining behavior have moved on, so too have DPTs. Killing two birds with one stone, Evans and Stanovich (2013, this issue) respond to five main criticisms of DPTs. Along with addressing each criticism in turn, they set out to clarify the essential defining characteristics that distinguish one form of higher order cognition from the other. The aim of this commentary is to consider the defining characteristics of Type 1 and Type 2 processing that have been proposed and to suggest that the evidence can be taken to support quantitative differences rather than qualitatively distinct processes. © The Author(s) 2013.

Viis raamatutäit poola näidendeid / Riina Mägi

Index Scriptorium Estoniae

Mägi, Riina, 1957-

2006-01-01

Tõlkija Hendrik Lindepuult ilmus viies tõlkekogumik poola dramaturgia tippteoseid tutvustavast sarjast. Seekord said kaante vahele Tadeusz Rozewiczi näidendid "Valge abielu", "Lõks" ja "Vana naine haub"

Hendrik Lindepuu esitleb uusi tõlkeraamatuid poola kirjandusest

Index Scriptorium Estoniae

2009-01-01

16. nov. esitleti Poola Vabariigi saatkonnas Marcin Świetlicki romaani "Kaksteist" ja luulekogu "Profaani laulud" ning Tadeusz Różewiczi luulekogu "Valitud luuletused : 1945-1995", tõlkija Hendrik Lindepuu

Evans blue dye-enhanced imaging of the brain microvessels using spectral focusing coherent anti-Stokes Raman scattering microscopy.

Directory of Open Access Journals (Sweden)

Bo-Ram Lee

Full Text Available We performed dye-enhanced imaging of mouse brain microvessels using spectral focusing coherent anti-Stokes Raman scattering (SF-CARS microscopy. The resonant signals from C-H stretching in forward CARS usually show high background intensity in tissues, which makes CARS imaging of microvessels difficult. In this study, epi-detection of back-scattered SF-CARS signals showed a negligible background, but the overall intensity of resonant CARS signals was too low to observe the network of brain microvessels. Therefore, Evans blue (EB dye was used as contrasting agent to enhance the back-scattered SF-CARS signals. Breakdown of brain microvessels by inducing hemorrhage in a mouse was clearly visualized using backward SF-CARS signals, following intravenous injection of EB. The improved visualization of brain microvessels with EB enhanced the sensitivity of SF-CARS, detecting not only the blood vessels themselves but their integrity as well in the brain vasculature.

V qn TK ,

African Journals Online (AJOL)

Dr Obe

TEMPERATURE DEPENDENT MODELS OF SEMICONDUCTOR DEVICES FOR. COMPUTER AIDED ANALYSIS OF ELECTRONIC TRANSDUCERS. BY. TADEUSZ SIDOR. DEPARTMENT OF ELECTRICAL ENGINEERING. UNIVERSITY OF NIGERIA, NSUKKA. (Received 27th April 1981). ABSTRACT. The paper presents ...

A Dose–Response Analysis of the Reproductive Effects of a Single Gestational Dose of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Male Long Evans Hooded Rat Offspring,

OpenAIRE

Gray, L. E.; Ostby, J. S.; Kelce, W. R.

1997-01-01

Male rats exposedin uteroto 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) display reduced fertility as a consequence of the direct action of TCDD on the epididymides, as well as delayed puberty and altered reproductive organ weights. The current study provides dose–response data for the reproductive effects of TCDD, administered during pregnancy, with an emphasis on the effects of TCDD on testicular, epididymal, and ejaculated sperm numbers. Long Evans Hooded rats were dosed by gavage with 0, 0....

Poola luule ime / Märt Väljataga

Index Scriptorium Estoniae

Väljataga, Märt, 1965-

2008-01-01

Arvustus: Rozewicz, Tadeusz. Alati fragment / tlk. Hendrik Lindepuu. Laiuse : H. Lindepuu, 2007 ; Herbert, Zbigniew. Valitud luuletused / tlk. Hendrik Lindepuu. Laiuse : H. Lindepuu, 2008 ; Szymborska, Wislawa. Oma aja lapsed / tlk. Hendrik Lindepuu. Laiuse : H. Lindepuu, 2008

Evans syndrome in children. Long-term outcome in a prospective French national observational cohort.

Directory of Open Access Journals (Sweden)

Nathalie eAladjidi

2015-09-01

Full Text Available Evans syndrome (ES is a rare autoimmune disorder whose long-term follow-up characteristics are unknown. Patients under 18 at the time of diagnosis of a first autoimmune cytopenia have been included since 2004 in a national prospective observational cohort. In 2014, 156 children diagnosed between 1981 and 2014 with ES, were analyzed. The median age at initial cytopenia was 5.4 (0.2-17.2 years old. For 85 sequential cases, the median delay between the episodes of AIHA and ITP was 2.4 years (0.1–16.3. The median follow-up since ES diagnosis was 6.5 years (0.1-28.8. ES revealed underlying diseases in 10% of children; in 60% of patients, various associated immune manifestations were observed, and ES remained primary in 30%. Five-year ITP and AIHA relapse-free survival were respectively 25% and 61%. In all, 69% of children required one or more than one second-line immune treatment and 15 patients (10% died at a median age of 14.3 years (1.7-28.1.This national work provides the first consistent clinical description for ES and underscores the high percentage of associated immune manifestations, the long-term complications, and treatment toxicities. Current challenges include the identification of underlying genetic immune dysregulations and better characterization of subgroups of patients and of second-line therapy strategies.

Adolescent social isolation does not lead to persistent increases in anxiety- like behavior or ethanol intake in female long-evans rats.

Science.gov (United States)

Butler, Tracy R; Carter, Eugenia; Weiner, Jeffrey L

2014-08-01

Clinically, early life stress and anxiety disorders are associated with increased vulnerability for alcohol use disorders. In male rats, early life stress, imparted by adolescent social isolation, results in long-lasting increases in a number of behavioral risk factors for alcoholism, including greater anxiety-like behaviors and ethanol (EtOH) intake. Several recent studies have begun to use this model to gain insight into the relationships among anxiety measures, stress, EtOH intake, and neurobiological correlates driving these behaviors. As prior research has noted significant sex differences in the impact of adolescent stress on anxiety measures and EtOH drinking, the current study was conducted to determine if this same model produces an "addiction vulnerable" phenotype in female rodents. Female Long Evans rats were socially isolated (SI; 1/cage) or group housed (GH; 4/cage) for 6 weeks during adolescence. After this housing manipulation, behavioral assessment was conducted using the elevated plus maze, response to novelty in an open field environment, and the light/dark box. After behavioral testing, home cage EtOH drinking was assessed across an 8-week period. No group differences were detected in any of the behavioral measures of unconditioned anxiety-like behavior. Greater EtOH intake and preference were observed in SI females but these differences did not persist. The SI/GH model, which results in robust and enduring increases in anxiety measures and EtOH self-administration in male Long Evans rats, did not result in similar behavioral changes in female rats. These data, and that of others, suggest that adolescent social isolation is not a useful model with which to study neurobiological substrates linking antecedent anxiety and addiction vulnerability in female rats. Given the compelling epidemiological evidence that the relationship between chronic adolescent stress and alcohol addiction is particularly strong in women, there is clearly an urgent need

Rare sugar D-psicose prevents progression and development of diabetes in T2DM model Otsuka Long-Evans Tokushima Fatty rats.

Science.gov (United States)

Hossain, Akram; Yamaguchi, Fuminori; Hirose, Kayoko; Matsunaga, Toru; Sui, Li; Hirata, Yuko; Noguchi, Chisato; Katagi, Ayako; Kamitori, Kazuyo; Dong, Youyi; Tsukamoto, Ikuko; Tokuda, Masaaki

2015-01-01

The fundamental cause of overweight and obesity is consumption of calorie-dense foods. We have introduced a zero-calorie sweet sugar, d-psicose (d-allulose), a rare sugar that has been proven to have strong antihyperglycemic and antihyperlipidemic effects, and could be used as a replacement of natural sugar for the obese and diabetic subjects. Above mentioned efficacy of d-psicose (d-allulose) has been confirmed in our previous studies on type 2 diabetes mellitus (T2DM) model Otsuka Long-Evans Tokushima Fatty (OLETF) rats with short-term treatment. In this study we investigated the long-term effect of d-psicose in preventing the commencement and progression of T2DM with the mechanism of preservation of pancreatic β-cells in OLETF rats. Treated OLETF rats were fed 5% d-psicose dissolved in water and control rats only water. Nondiabetic control rats, Long-Evans Tokushima Otsuka (LETO), were taken as healthy control and fed water. To follow the progression of diabetes, periodic measurements of blood glucose, plasma insulin, and body weight changes were continued till sacrifice at 60 weeks. Periodic in vivo body fat mass was measured. On sacrifice, pancreas, liver, and abdominal adipose tissues were collected for various staining tests. d-Psicose prevented the commencement and progression of T2DM till 60 weeks through the maintenance of blood glucose levels, decrease in body weight gain, and the control of postprandial hyperglycemia, with decreased levels of HbA1c in comparison to nontreated control rats. This improvement in glycemic control was accompanied by the maintenance of plasma insulin levels and the preservation of pancreatic β-cells with the significant reduction in inflammatory markers. Body fat accumulation was significantly lower in the treatment group, with decreased infiltration of macrophages in the abdominal adipose tissue. Our findings suggest that the rare sugar d-psicose could be beneficial for the prevention and control of obesity and

Four weeks' inhalation exposure of Long Evans rats to 4-tert-butyltoluene: Effect on evoked potentials, behaviour and brain neurochemistry

DEFF Research Database (Denmark)

Lam, Henrik Rye; Ladefoged, Ole; Østergaard, Grete

2000-01-01

Long-lasting central nervous system (CNS) neurotoxicity of 4-tert-butyltoluene (TBT) has been investigated using electrophysiology, behaviour, and neurochemistry in Long Evans rats exposed by inhalation to 0, 20, or 40 p.p.m. TBT 6 hr/day, 7 days/week for 4 weeks. Flash evoked potentials...... and somatosensory evoked potentials were not affected by TBT In Auditory Brain Stem Response there was no shift in hearing threshold, but the amplitude of the first wave was increased in both exposed groups at high stimulus levels. Three to four months after the end of exposure, behavioural studies in Morris water...... maze and eight-arm maze failed to demonstrate any TBT induced effects. Exposure was followed by a 5 months exposure-free period prior to gross regional and subcellular (synaptosomal) neurochemical investigations of the brain. TBT reduced the NA concentration in whole brain minus cerebellum...

Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc

Energy Technology Data Exchange (ETDEWEB)

Medici, Valentina; Sturniolo, Giacomo Carlo; D' Inca, Renata [Department of Surgical and Gastroenterological Sciences, University of Padua, Padua (Italy); Santon, Alessandro; Giannetto, Sabrina; Albergoni, Vincenzo; Irato, Paola [Department of Biology, University of Padua, via U. Bassi 58/B, 35131 Padua (Italy)

2002-09-01

The Long-Evans Cinnamon (LEC) rat is a mutant animal model for Wilson's disease. It is known that an abnormal accumulation of Cu and Fe in the liver and low concentrations of both ceruloplasmin and Cu in the serum occur in these rats. The accumulation of Cu is explained by the defective expression of the Cu-transporting P-type ATPase gene, homologous to the gene for Wilson's disease (ATP7B). The aim of this work was to clarify the action mechanism of Zn, and to verify the role that this metal plays in LEC rats in short-term treatment experiments (1 and 2 weeks) on concentrations of Cu, Zn, Fe, metallothionein (MT), 8-hydroxy-2'-deoxyguanosine (oh{sup 8}dG) and on the activity of antioxidant enzymes. It is well known that Zn induces MT and has the ability to prevent redox-active metals, Cu and Fe, binding to and causing oxidative damage at active sites of Zn metalloenzymes and nonspecific binding sites on proteins. Zn administration reduces Cu and Fe transport from mucosal to serosal intestinal sides through competitive mechanisms. Our findings show that treatment with zinc acetate increases tissue Zn and MT contents and decreases Cu and Fe concentrations in the liver and kidneys, even if hepatic Zn and MT concentrations decrease with treatment period. Induction of MT synthesis by Zn contributes to the reduction in free radicals produced by Cu and Fe. We also observed that the superoxide dismutase (SOD)activity in liver decreases with treatment duration in association with the Cu and Fe liver decrease. However, the SOD activity in kidney increases in untreated rats at 2 weeks relative to those untreated for 1 week. (orig.)

Evans hole and non linear optical activity in Bis(melaminium) sulphate dihydrate: A vibrational spectral study.

Science.gov (United States)

Suresh Kumar, V R; Binoy, J; Dawn Dharma Roy, S; Marchewka, M K; Jayakumar, V S

2015-01-01

Bis(melaminium) sulphate dihydrate (BMSD), an interesting melaminium derivative for nonlinear optical activity, has been subjected to vibrational spectral analysis using FT IR and FT Raman spectra. The analysis has been aided by the Potential Energy Distribution (PED) of vibrational spectral bands, derived using density functional theory (DFT) at B3LYP/6-31G(d) level. The geometry is found to correlate well with the XRD structure and the band profiles for certain vibrations in the finger print region have been theoretically explained using Evans hole. The detailed Natural Bond Orbital (NBO) analysis of the hydrogen bonding in BMSD has also been carried out to understand the correlation between the stabilization energy of hyperconjugation of the lone pair of donor with the σ(∗) orbital of hydrogen-acceptor bond and the strength of hydrogen bond. The theoretical calculation shows that BMSD has NLO efficiency, 2.66 times that of urea. The frontier molecular orbital analysis points to a charge transfer, which contributes to NLO activity, through N-H…O intermolecular hydrogen bonding between the melaminium ring and the sulphate. The molecular electrostatic potential (MEP) mapping has also been performed for the detailed analysis of the mutual interactions between melaminium ring and sulphate ion. Copyright © 2015 Elsevier B.V. All rights reserved.

University of Geneva honours LHC project leader Lyn Evans at 450th anniversary ceremony. The honorary degrees, which recognize endeavours in human rights and in fostering dialogue between nations, were also awarded to Mary Robinson, Desmond Tutu, as well as Pascal Lamy .

CERN Multimedia

Maximilien Brice

2009-01-01

University of Geneva honours LHC project leader Lyn Evans at 450th anniversary ceremony. The honorary degrees, which recognize endeavours in human rights and in fostering dialogue between nations, were also awarded to Mary Robinson, Desmond Tutu, as well as Pascal Lamy .

Perturbations to the lower ionosphere by tropical cyclone Evan in the South Pacific Region

Science.gov (United States)

Kumar, Sushil; NaitAmor, Samir; Chanrion, Olivier; Neubert, Torsten

2017-08-01

Very low frequency (VLF) electromagnetic signals from navigational transmitters propagate worldwide in the Earth-ionosphere waveguide formed by the Earth and the electrically conducting lower ionosphere. Changes in the signal properties are signatures of variations in the conductivity of the reflecting boundary of the lower ionosphere which is located in the mesosphere and lower thermosphere, and their analysis is, therefore, a way to study processes in these remote regions. Here we present a study on amplitude perturbations of local origin on the VLF transmitter signals (NPM, NLK, NAA, and JJI) observed during tropical cyclone (TC) Evan, 9-16 December 2012 when TC was in the proximity of the transmitter-receiver links. We observed a maximum amplitude perturbation of 5.7 dB on JJI transmitter during 16 December event. From Long Wave Propagation Capability model applied to three selected events we estimate a maximum decrease in the nighttime D region reference height (H') by 5.2 km (13 December, NPM) and maximum increase in the daytime D region H' by 6.1 km and 7.5 km (14 and 16 December, JJI). The results suggest that the TC caused the neutral densities of the mesosphere and lower thermosphere to lift and sink (bringing the lower ionosphere with it), an effect that may be mediated by gravity waves generated by the TC. The perturbations were observed before the storm was classified as a TC, at a time when it was a tropical depression, suggesting the broader conclusion that severe convective storms, in general, perturb the mesosphere and the stratosphere through which the perturbations propagate.

Opioidergic and dopaminergic modulation of cost/benefit decision-making in Long Evans Rats.

Science.gov (United States)

Morales, Ileana; Currie, Paul J; Hackenberg, Timothy D; Pastor, Raúl

2017-10-01

Eating disorders are associated with impaired decision-making and dysfunctional reward-related neurochemistry. The present study examined the potential contributions of dopamine and opioid signaling to these processes using two different decision-making tasks. In one task, Long Evans Rats chose between working for a preferred food (high-carbohydrate banana-flavored sucrose pellets) by lever pressing on a progressive-ratio schedule of reinforcement vs. obtaining less preferred laboratory chow that was concurrently available. In a second (effort-free) task, rats chose between the same two reinforcers when they were both available freely. Rats were trained in these tasks before receiving haloperidol (0.00, 0.05, 0.10mg/kg, intraperitoneally (i.p.)) or naloxone (0.0, 1.5, 3.0mg/kg, i.p.). In the first task, haloperidol decreased breakpoint, lever presses, number of reinforcers earned, and increased chow intake, whereas naloxone decreased breakpoint and number of reinforcers earned but had no effect on chow consumption. In the effort-free task, haloperidol reduced intakes of both foods without affecting preference, whereas naloxone selectively reduced the consumption of banana-pellets. The present findings support converging evidence suggesting that DA signaling affects processes more closely related to appetitive motivation, leaving other components of motivation unchanged. By contrast, opioid signaling appears to mediate aspects of hedonic feeding by selectively altering intakes of highly palatable foods. For preferred foods, both appetitive and consummatory aspects of food intake were altered by opioid receptor antagonism. Our findings argue against a general suppression of appetite by either compound, as appetite manipulations have been shown to unselectively alter intakes of both types of food regardless of the task employed. Copyright © 2017 Elsevier Inc. All rights reserved.

Rozprawa o przypływach i odpływach morza

Directory of Open Access Journals (Sweden)

Galileo Galilei

2014-06-01

Full Text Available The paper presents the first polish translation (by Tadeusz Sierotowicz of Galileo’s letter on tides written in the begining of the year 1616 to cardinal Alessandro Orsini. The text of translation is organized in a new way, and integrated with the index of matters.

Poola luule ime / Märt Väljataga

Index Scriptorium Estoniae

Väljataga, Märt, 1965-

2008-01-01

Rets. rmt. : Różewicz, Tadeusz. Alati fragment / poola keelest tõlkinud Hendrik Lindepuu. Laiuse : Hendrik Lindepuu Kirjastus, 2007; Herbert, Zbigniew. Valitud luuletused / poola keelest tõlkinud Hendrik Lindepuu. Laiuse : H. Lindepuu, 2008; Szymborska, Wislawa. Oma aja lapsed / poola keelest tõlkinud Hendrik Lindepuu. Laiuse : H. Lindepuu, 2008

Analysis of sensitivity to MK-801 treatment in a novel active allothetic place avoidance task and in the working memory version of the Morris water maze reveals differences between Long-Evans and Wistar rats

Czech Academy of Sciences Publication Activity Database

Valeš, Karel; Bubeníková-Valešová, V.; Klement, Daniel; Stuchlík, Aleš

2006-01-01

Roč. 55, č. 4 (2006), s. 383-388 ISSN 0168-0102 R&D Projects: GA MZd(CZ) NL7684; GA MŠk(CZ) 1M0517; GA MŠk(CZ) LC554; GA ČR(CZ) GP309/03/P126; GA ČR(CZ) GA309/06/1231 Institutional research plan: CEZ:AV0Z50110509 Keywords : Wistar/Long-Evans rats * MK-801 * cognition Subject RIV: FH - Neurology Impact factor: 1.953, year: 2006

Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats

Energy Technology Data Exchange (ETDEWEB)

Stanko, Jason [National Institute of Environmental Health Sciences (NIEHS); Enoch, Rolondo [North Carolina Central University, Durham; Rayner, Jennifer L [ORNL; Davis, Christine [U.S. Environmental Protection Agency; Wolf, Douglas [U.S. Environmental Protection Agency; Malarkey, David [University of North Carolina, Chapel Hill; Fenton, Suzanne [National Institute of Environmental Health Sciences (NIEHS)

2010-12-01

The present study examines the postnatal reproductive development of male rats following prenatal exposure to an atrazine metabolite mixture (AMM) consisting of the herbicide atrazine and its environmental metabolites diaminochlorotriazine, hydroxyatrazine, deethylatrazine, and deisopropylatrazine. Pregnant Long-Evans rats were treated by gavage with 0.09, 0.87, or 8.73 mg AMM/kg body weight (BW), vehicle, or 100 mg ATR/kg BW positive control, on gestation days 15 19. Preputial separation was significantly delayed in 0.87 mg and 8.73 mg AMM-exposed males. AMM-exposed males demonstrated a significant treatment-related increase in incidence and severity of inflammation in the prostate on postnatal day (PND) 120. A dose-dependent increase in epididymal fat masses and prostate foci were grossly visible in AMM-exposed offspring. These results indicate that a short, late prenatal exposure to mixture of chlorotriazine metabolites can cause chronic prostatitis in male LE rats. The mode of action for these effects is presently unclear.

IPDO-2007: Inverse Problems, Design and Optimization Symposium

Science.gov (United States)

2007-08-01

Grebenniko v J. Luna Tomas Perez Manuel Enriquez 025 Alexande r Grebenniko v 026 Tsung- Chien Chen Shou- Jen Hsu Pan-Chio Tuan 028...Dulikravich 086 Helmut Sobieczky Monika Hannemann 087 Anssi Lehikoinen Arto Voutilainen Jari Kaipio Stefan Finsterle Mike Kowalsky 088

Eesti noorkunstnikud unistavad Poolas

Index Scriptorium Estoniae

2000-01-01

8. märtsist Sopoti galeriis Marzenie Provincionalnej Dziewczyny (Provintsitüdruku unistus) samanimelise näitusesarja näitus 'Provintsipoisi unistus'. Kuraator Paulina M. Olowska. Eestist osalesid Jasper Zoova, Tarrvi Laamannn, Kiwa. Poola kunstiteadlane Flavek Kowalsky eestlaste töödest.

Francis Bacon czyli Diego Velázquez na fotelu dentystycznym - malarskie i inne cytaty jako "dodatek" do rozpraszającego się życia

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van Nieukerken, A.

2014-01-01

"Francis Bacon or Diego Velázquez in a dentist’s chair" - pictorial and other kinds of quotations as an addition to a disintegrating life The mature poetry of Tadeusz Różewicz seems to be at odds with both modernist and postmodern literary tenets. It undeniably makes abundant use of intertextuality

Ethanol seeking by Long Evans rats is not always a goal-directed behavior.

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Regina A Mangieri

Full Text Available Two parallel and interacting processes are said to underlie animal behavior, whereby learning and performance of a behavior is at first via conscious and deliberate (goal-directed processes, but after initial acquisition, the behavior can become automatic and stimulus-elicited (habitual. With respect to instrumental behaviors, animal learning studies suggest that the duration of training and the action-outcome contingency are two factors involved in the emergence of habitual seeking of "natural" reinforcers (e.g., sweet solutions, food or sucrose pellets. To rigorously test whether behaviors reinforced by abused substances such as ethanol, in particular, similarly become habitual was the primary aim of this study.Male Long Evans rats underwent extended or limited operant lever press training with 10% sucrose/10% ethanol (10S10E reinforcement (variable interval (VI or (VR ratio schedule of reinforcement, or with 10% sucrose (10S reinforcement (VI schedule only. Once training and pretesting were complete, the impact of outcome devaluation on operant behavior was evaluated after lithium chloride injections were paired with the reinforcer, or unpaired 24 hours later. After limited, but not extended instrumental training, lever pressing by groups trained under VR with 10S10E and under VI with 10S was sensitive to outcome devaluation. In contrast, responding by both the extended and limited training 10S10E VI groups was not sensitive to ethanol devaluation during the test for habitual behavior.Operant behavior by rats trained to self-administer an ethanol-sucrose solution showed variable sensitivity to a change in the value of ethanol, with relative insensitivity developing sooner in animals that received time-variable ethanol reinforcement during training sessions. One important implication, with respect to substance abuse in humans, is that initial learning about the relationship between instrumental actions and the opportunity to consume ethanol

Cyber Victimization in High School: Measurement, Overlap with Face-to-Face Victimization, and Associations with Social-Emotional Outcomes

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Brown, Christina Flynn; Demaray, Michelle Kilpatrick; Tennant, Jaclyn E.; Jenkins, Lyndsay N.

2017-01-01

Cyber victimization is a contemporary problem facing youth and adolescents (Diamanduros, Downs, & Jenkins, 2008; Kowalski & Limber, 2007). It is imperative for researchers and school personnel to understand the associations between cyber victimization and student social-emotional outcomes. This article explores (a) gender differences in…

75 FR 38608 - Departmental Offices: Privacy Act of 1974, as Amended

Science.gov (United States)

2010-07-02

... Justice (``DOJ'') and the Federal financial regulators who supervise and regulate financial institutions...: Theodore R. Kowalsky, Manager, Data & Information Technology, Office of Financial Agents, Department of the.... Additionally, the Bank of New York Mellon (``BNYM'') has been designated as another Financial Agent for the...

The Prevalence of Cyber Bullying Victimization and Its Relationship to Academic, Social, and Emotional Adjustment among College Students

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Beebe, Jennifer Elizabeth

2010-01-01

The current study investigated the prevalence and frequency of cyber bullying victimization and examined the impact of cyber bullying on academic, social, and emotional college adjustment. Participants were recruited from two universities in the United States. Participants completed the Revised Cyber Bullying Survey (Kowalski & Limber, 2007)…

Bullying as an Institutionally Exclusionary Practice--Implications of Ignoring Culturally Specific Support Needs of Black Male Students in Further Education (FE)

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Peart, Sheine

2015-01-01

Stereotypical bullying is usually configured as actions that occur between individuals where there is an "imbalance of power or strength" (Kowalski, Lomber and Agatston). However, bullying can also be conceived as an organisational process, where systemised institutional practices results in "the collective failure?…?of an…

Review of Selected Dissertations Addressing School Public Relations, Administrator Communication, and Conflict Resolution

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Decman, John M.; Simieou, Felix, III

2009-01-01

This article is an extension to Kowalski's (2005) identification of possible lines of scholarly inquiry into themes related to schools and public relations. The article first cites professional accreditation standards for educational leaders as significant factors in providing a framework for increased scholarly inquiry. It then summarizes the…

pp-waves in 11-dimensions

International Nuclear Information System (INIS)

Gauntlett, Jerome P.; Hull, Christopher M.

2002-01-01

The Killing spinor equations for pp-wave solutions of eleven dimensional supergravity are analysed and it is shown that there are solutions that preserve 18, 20, 22 and 24 supersymmetries, in addition to the generic solution preserving 16 supersymmetries and the Kowalski-Glikman solution preserving 32 supersymmetries. (author)

Improving urban visibility through fractal analysis of street edges: The case of John Evans Atta Mills High Street in Accra, Ghana

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R.A. Oppong

2017-06-01

Full Text Available Streets are a representation of cities, and the image of a city is a reflection of its home country. Although attempts to ensure harmonious spatial and environmental development in Ghanaian settlements date back to the colonial era, these efforts have minimal physical manifestation in the urban fabric of the city of Accra. The Independence Arch of Ghana, an important landmark in the urban fabric and history of Accra, lacks the striking vista and approach it deserves. This paper introduces the use of fractal analysis of street edges to understand the characteristics of the John Evans Atta Mills (JEAM High Street for developing recommendations to improve visibility along its stretch and the overall image of the city. The box-counting method with visual survey was used in research. The pertinent questions this paper seeks to address are as follows: What factors affect the visibility and imageability of JEAM High Street? What design aspects should be considered to improve urban visibility along JEAM High Street? What is the link of fractals to urban design and architecture? The paper recommends various design considerations and qualities to improve the urban visibility and imageability of JEAM High Street.

Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats

International Nuclear Information System (INIS)

Rayner, Jennifer L.; Enoch, Rolondo R.; Wolf, Douglas C.; Fenton, Suzanne E.

2007-01-01

Studies showed that early postnatal exposure to the herbicide atrazine (ATR) delayed preputial separation (PPS) and increased incidence of prostate inflammation in adult Wistar rats. A cross-fostering paradigm was used in this study to determine if gestational exposure to ATR would also result in altered puberty and reproductive tissue effects in the male rat. Timed-pregnant Long-Evans (LE) rats were dosed by gavage on gestational days (GD) 15-19 with 100 mg ATR/kg body weight (BW) or 1% methylcellulose (controls, C). On postnatal day (PND)1, half litters were cross-fostered, creating 4 treatment groups; C-C, ATR-C, C-ATR, and ATR-ATR (transplacental-milk as source, respectively). On PND4, male offspring in the ATR-ATR group weighed significantly less than the C-C males. ATR-ATR male pups had significantly delayed preputial separation (PPS). BWs at PPS for C-ATR and ATR-ATR males were reduced by 6% and 9%, respectively, from that of C-C. On PND120, lateral prostate weights of males in the ATR-ATR group were significantly increased over C-C. Histological examination of lateral and ventral prostates identified an increased distribution of inflammation in the lateral prostates of C-ATR males. By PND220, lateral prostate weights were significantly increased for ATR-C and ATR-ATR, but there were no significant changes in inflammation in either the lateral or ventral prostate. These results suggest that in LE rats, gestational ATR exposure delays PPS when male offspring suckle an ATR dam, but leads to increased lateral prostate weight via transplacental exposure alone. Inflammation present at PND120 does not increase in severity with time

Attenuation of Diabetic Nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF Rats with a Combination of Chinese Herbs (Tangshen Formula

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Haojun Zhang

2011-01-01

Full Text Available Diabetic nephropathy is one of the most significant microvascular complications in patients with type 2 diabetics. The concise mechanism of diabetic nephropathy is unknown and there is no successful treatment. The objective of study was to investigate effects of Chinese herbs (Tangshen Formula on diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF rats. OLETF rats and LETO rats were divided into four groups: LETO control, OLETF diabetics, OLETF diabetics treated with Tangshen Formula, and OLETF diabetics treated with Monopril. Body weight, blood glucose, and 24 h urinary proteins were measured once every four weeks. Blood samples and kidney tissues were obtained for analyses of total cholesterol, triglyceride, whole blood viscosity, plasma viscosity, and pathohistological examination at 36 and 56 weeksrespectively. Untreated OLETF rats displayed diabetic nephropathy over the study period. Treatment of OLETF rats with Tangshen Formula attenuated the increases in blood glucose, body weight, 24 h urinary protein content, serum total cholesterol, whole blood viscosity and plasma viscosity at certain time. Treatment with Tangshen Formula also reduced glomerulosclerotic index and interstitial fibrotic index seen in OLETF rats. In conclusion, Tangshen Formula could attenuate the development of diabetic nephropathy in OLETF rat diabetic model.

Fatal pulmonary embolism following splenectomy in a patient with Evan's syndrome: case report and review of the literature.

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Monga, Varun; Maliske, Seth M; Perepu, Usha

2017-01-01

Evans syndrome (ES) is a rare disease characterized by simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP) with or without immune neutropenia. Splenectomy is one of the treatment options for disease refractory to medical therapy. Venous thromboembolism (VTE) following splenectomy for hematological diseases has an incidence of 10%. Here we describe a case report of a young patient hospitalized with severe hemolytic anemia with Hgb 4.8 g/dl. He developed thrombocytopenia with platelet nadir of 52,000/mm 3 , thus formally diagnosed with ES. He failed standard medical therapy. He underwent splenectomy and had a fatal outcome. Autopsy confirmed the cause of death as pulmonary embolism (PE). This case report and review of the literature highlight important aspects of the association between VTE, splenectomy, and hemolytic syndromes including the presence of thrombocytopenia. The burden of the disease is reviewed as well as various pathophysiologic mechanisms contributing to thromboembolic events in these patients and current perioperative prophylactic anticoagulation strategies. Despite an advancing body of literature increasing awareness of VTE following splenectomy, morbidity and mortality remains high. Identifying high risk individuals for thromboembolic complications from splenectomy remains a challenge. There are no consensus guidelines for proper perioperative and post-operative anti-coagulation. We encourage future research to determine which factors might be playing a role in increasing the risk for VTE in real time with hope of forming a consensus to guide management.

Proceedings of the United States Air Force STINFO Officers Policy Conference - 1981,

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1982-08-01

breakthrough might sound the death knell for the STI community. A new information community would fill the vacuum, they contended. The study was completed a...OH 45433 Knudtson, Gail AFWAL/TST Horseman , Hazel WPAFB OH 45433 AFWAL/TST WPAFB OH 45433 Kowalsky, Tom HQ MAC/XPSR Huff, Frank Scott AFB IL 62225

Obesity and type 2 diabetes, not a diet high in fat, sucrose, and cholesterol, negatively impacts bone outcomes in the hyperphagic Otsuka Long Evans Tokushima Fatty rat.

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Ortinau, Laura C; Linden, Melissa A; Dirkes, Rebecca; Rector, R Scott; Hinton, Pamela S

2017-12-01

Obesity and type 2 diabetes (T2D) increase fracture risk; however, the association between obesity/T2D may be confounded by consumption of a diet high in fat, sucrose, and cholesterol (HFSC). The study objective was to determine the main and interactive effects of obesity/T2D and a HFSC diet on bone outcomes using hyperphagic Otuska Long Evans Tokushima Fatty (OLETF) rats and normophagic Long Evans Tokushima Otsuka (LETO) controls. At 8weeks of age, male OLETF and LETO rats were randomized to either a control (CON, 10 en% from fat as soybean oil) or HFSC (45 en% from fat as soybean oil/lard, 17 en% sucrose, and 1wt%) diet, resulting in four treatment groups. At 32weeks, total body bone mineral content (BMC) and density (BMD) and body composition were measured by dual-energy X-ray absorptiometry, followed by euthanasia and collection of blood and tibiae. Bone turnover markers and sclerostin were measured using ELISA. Trabecular microarchitecture of the proximal tibia and geometry of the tibia mid-diaphysis were measured using microcomputed tomography; whole-bone and tissue-level biomechanical properties were evaluated using torsional loading of the tibia. Two-factor ANOVA was used to determine main and interactive effects of diet (CON vs. HFSC) and obesity/T2D (OLETF vs. LETO) on bone outcomes. Hyperphagic OLEFT rats had greater final body mass, body fat, and fasting glucose than normophagic LETO, with no effect of diet. Total body BMC and serum markers of bone formation were decreased, and bone resorption and sclerostin were increased in obese/T2D OLETF rats. Trabecular bone volume and microarchitecture were adversely affected by obesity/T2D, but not diet. Whole-bone and tissue-level biomechanical properties of the tibia were not affected by obesity/T2D; the HFSC diet improved biomechanical properties only in LETO rats. Obesity/T2D, regardless of diet, negatively impacted the balance between bone formation and resorption and trabecular bone volume and

Markers for blood-brain barrier integrity: how appropriate is Evans blue in the 21st century and what are the alternatives?

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Norman Ruthven Saunders

2015-10-01

Full Text Available In recent years there has been a resurgence of interest in brain barriers and various roles their intrinsic mechanisms may play in neurological disorders. Such studies require suitable models and markers to demonstrate integrity and functional changes at the interfaces between blood, brain and cerebrospinal fluid. Studies of brain barrier mechanisms and measurements of plasma volume using dyes have a long-standing history, dating back to the late 19th-Century. Their use continues in spite of their known serious limitations in in vivo applications. These were well known when first introduced, but seem to have been forgotten since. Understanding these limitations is important because Evans blue is still the most commonly used marker of brain barrier integrity and those using it seem oblivious to problems arising from its in vivo application. The introduction of HRP in the mid 20th-Century was an important advance because its reaction product can be visualized at the electron microscopical level. Advantages and disadvantages these markers will be discussed together with a critical evaluation of alternative approaches. There is no single marker suitable for all purposes. A combination of different sized, visualisable dextrans and radiolabelled molecules currently seems to be the most appropriate approach for qualitative and quantitative assessment of barrier integrity.

The Impact of Bullying on School Performance in Six Selected Schools in South Carolina

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Cooper, Stephanie A.

2011-01-01

The nation's K-12 schools are faced with numerous critical challenges, such as elevating academic achievement, and meeting No Child Left Behind state standards (Kowalski et al., 2008). But bullying in schools is becoming one of the most challenging issues that school personnel are encountering. In a Stanford University, study it was revealed that…

Bully versus Victim on the Internet: The Correlation with Emotional-Social Characteristics

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Eden, Sigal; Heiman, Tali; Olenik-Shemesh, Dorit

2016-01-01

Cyberbullying is a repeated violent behavior aimed at hurting another person directed by an individual or a group towards the victim using technological means such as a computer or a mobile phone (Kowalski, Morgan, and Limber, 2012). The current study examined the phenomenon of cyberbullying among children and youth in Israel. The purpose of was…

"Nice guys finish last": influence of mate choice on reproductive success in Long-Evans rats.

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Winland, C; Bolton, J L; Ford, B; Jampana, S; Tinker, J; Frohardt, R J; Guarraci, F A; Zewail-Foote, M

2012-02-01

The present study was designed to determine if male physiology and male reproductive behavior predict reproductive success in Long-Evans rats. Mating behavior was observed in sexually naïve, naturally cycling female rats during behavioral estrous that were given the opportunity to mate with two males simultaneously. DNA analysis of offspring born following these mating encounters was used to identify the paternity of each pup. In order to assess the effect of mate choice during these mating encounters on reproductive success, one male rat in each pair was categorized as the preferred mate if the female spent more time (>50%) with him during the mating test of the present study. Furthermore, each male in the pairs was categorized as "attractive" or "non-attractive" by computing the number of females that preferred each male across many mating tests. Similar to results reported in Lovell et al. (2007), during 76% of these mating tests the same male rat in each pair was preferred by different female rats. Overall attractiveness of individual male rats predicted reproductive success in the present study. Interestingly, "attractive" males sired significantly FEWER pups than "non-attractive" males. Neither behavioral (e.g., latency to first sexual stimulation, number of sexual stimulations) nor physiological measures (e.g., body weight, urinary testosterone levels) of male rats predicted their reproductive success. In conclusion, the present results indicate that certain features of some males are more attractive to females, but attractive males are at a reproductive disadvantage (as measured by the number of pups sired). Although basal urinary testosterone levels did not differ between males that sired the majority of pups in a litter and males that sired few or none of the pups in a litter, aggression and/or other physiological measures of fertility (e.g., penile reflexes) may differ between males that are attractive to females and those that have a reproductive

The effects of cannabidiol (CBD) on Δ⁹-tetrahydrocannabinol (THC) self-administration in male and female Long-Evans rats.

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Wakeford, Alison G P; Wetzell, Bradley B; Pomfrey, Rebecca L; Clasen, Matthew M; Taylor, William W; Hempel, Briana J; Riley, Anthony L

2017-08-01

Despite widespread cannabis use in humans, few rodent models exist demonstrating significant Δ⁹-tetrahydrocannabinol (THC) self-administration, possibly due to THC's co-occurring aversive effects, which impact drug reinforcement. Cannabis contains a number of phytocannabinoids in addition to THC, one of which, cannabidiol (CBD), has been reported to antagonize some of the aversive effects of THC. Given such effects of CBD, it is possible that it might influence THC intravenous self-administration in rodents. Accordingly, male and female Long-Evans rats were trained to self-administer THC over a 3-week period and then were assessed for the effects of CBD on responding for THC at 1:1 and 1:10 dose ratios or for the establishment of cocaine self-administration (as a positive control for drug self-administration). Consistent with previous research, THC self-administration was modest and only evident in a subset of animals (and unaffected by sex). Cocaine self-administration was high and evident in the majority of animals tested, indicating that the design was sensitive to drug reinforcement. There was no effect of CBD pretreatment on THC intravenous self-administration at any CBD:THC dose ratio. Future developments of animal models of THC self-administration and the examination of factors that affect its display remain important to establish procedures designed to assess the basis for and treatment of cannabis use and abuse. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats.

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Morales, Melissa; McGinnis, Molly M; McCool, Brian A

2015-12-01

The current experiment examined the effects of 10 days of chronic intermittent ethanol (CIE) exposure on anxiety-like behavior and home cage ethanol intake using a 20% intermittent access (M, W, F) paradigm in male and female Long-Evans rats. Withdrawal from alcohol dependence contributes to relapse in humans and increases in anxiety-like behavior and voluntary ethanol consumption in preclinical models. Our laboratory has shown that 10 days of CIE exposure produces both behavioral and neurophysiological alterations associated with withdrawal in male rats; however, we have yet to examine the effects of this exposure regime on ethanol intake in females. During baseline, females consumed more ethanol than males but, unlike males, did not show escalations in intake. Rats were then exposed to CIE and were again given intermittent access to 20% ethanol. CIE males increased their intake compared to baseline, whereas air-exposed males did not. Ethanol intake in females was unaffected by CIE exposure. Notably, both sexes expressed significantly elevated withdrawal-associated anxiety-like behavior in the plus maze. Finally, rats were injected with the cannabinoid CB1 receptor antagonist, SR141716A (0, 1, 3, 10mg/kg, i.p.) which reduced ethanol intake in both sexes. However, females appear to be more sensitive to lower doses of this CB1 receptor antagonist. Our results show that females consume more ethanol than males; however, they did not escalate their intake using the intermittent access paradigm. Unlike males, CIE exposure had no effect on drinking in females. It is possible that females may be less sensitive than males to ethanol-induced increases in drinking after a short CIE exposure. Lastly, our results demonstrate that males and females may have different pharmacological sensitivities to CB1 receptor blockade on ethanol intake, at least under the current conditions. Copyright © 2015 Elsevier Inc. All rights reserved.

Behavioral Phenotyping of Juvenile Long-Evans and Sprague-Dawley Rats: Implications for Preclinical Models of Autism Spectrum Disorders.

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Katherine M Ku

Full Text Available The laboratory rat is emerging as an attractive preclinical animal model of autism spectrum disorder (ASD, allowing investigators to explore genetic, environmental and pharmacological manipulations in a species exhibiting complex, reciprocal social behavior. The present study was carried out to compare two commonly used strains of laboratory rats, Sprague-Dawley (SD and Long-Evans (LE, between the ages of postnatal day (PND 26-56 using high-throughput behavioral phenotyping tools commonly used in mouse models of ASD that we have adapted for use in rats. We detected few differences between young SD and LE strains on standard assays of exploration, sensorimotor gating, anxiety, repetitive behaviors, and learning. Both SD and LE strains also demonstrated sociability in the 3-chamber social approach test as indexed by spending more time in the social chamber with a constrained age/strain/sex matched novel partner than in an identical chamber without a partner. Pronounced differences between the two strains were, however, detected when the rats were allowed to freely interact with a novel partner in the social dyad paradigm. The SD rats in this particular testing paradigm engaged in play more frequently and for longer durations than the LE rats at both juvenile and young adult developmental time points. Results from this study that are particularly relevant for developing preclinical ASD models in rats are threefold: (i commonly utilized strains exhibit unique patterns of social interactions, including strain-specific play behaviors, (ii the testing environment may profoundly influence the expression of strain-specific social behavior and (iii simple, automated measures of sociability may not capture the complexities of rat social interactions.

Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

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Oh, Da Hee; Kim, Jung Yeon; Lee, Bong Gn; You, Jeong Soon; Chang, Kyung Ja; Chung, Hyunju; Yoo, Myung Chul; Yang, Hyung-In; Kang, Ja-Heon; Hwang, Yoo Chul; Ahn, Kue Jeong; Chung, Ho-Yeon

2012-01-01

This study aimed to determine whether taurine supplementation improves metabolic disturbances and diabetic complications in an animal model for type 2 diabetes. We investigated whether taurine has therapeutic effects on glucose metabolism, lipid metabolism, and diabetic complications in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term duration of diabetes. Fourteen 50-week-old OLETF rats with chronic diabetes were fed a diet supplemented with taurine (2%) or a non-supplemented control diet for 12 weeks. Taurine reduced blood glucose levels over 12 weeks, and improved OGTT outcomes at 6 weeks after taurine supplementation, in OLETF rats. Taurine significantly reduced insulin resistance but did not improve β-cell function or islet mass. After 12 weeks, taurine significantly decreased serum levels of lipids such as triglyceride, cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol. Taurine significantly reduced serum leptin, but not adiponectin levels. However, taurine had no therapeutic effect on damaged tissues. Taurine ameliorated hyperglycemia and dyslipidemia, at least in part, by improving insulin sensitivity and leptin modulation in OLETF rats with long-term diabetes. Additional study is needed to investigate whether taurine has the same beneficial effects in human diabetic patients. PMID:23114424

Chronic social instability increases anxiety-like behavior and ethanol preference in male Long Evans rats.

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Roeckner, Alyssa R; Bowling, Alexandra; Butler, Tracy R

2017-05-01

Chronic stress during adolescence is related to increased prevalence of anxiety disorders and alcohol use disorders in humans. This phenotype has been consistently recapitulated in animal models with male subjects, but models using female subjects are fewer. The aim of these studies was to test the hypothesis that chronic social instability (CSI) during adolescence engenders increased anxiety-like behavior, increased corticosterone, and greater ethanol intake and/or preference than control groups in male and female rats. A chronic social instability (CSI) procedure was conducted in separate cohorts of female and male adolescent Long Evans rats. CSI included daily social isolation for 1h, and then pair housing with a novel cage mate for 23h until the next 1h isolation period from PND 30-46. Control groups included social stability (SS), chronic isolation (ISO), and acute social instability (aSI). At PND 49-50, anxiety-like behavior was assessed on the elevated plus maze, and on PND 51 tails bloods were obtained for determination of corticosterone (CORT) levels. This was followed by 4weeks of ethanol drinking in a home cage intermittent access ethanol drinking paradigm (PND 55-81 for males, PND 57-83 for females). Planned contrast testing showed that the male CSI group had greater anxiety-like behavior compared controls, but group differences were not apparent for CORT. CSI males had significantly higher levels of ethanol preference during drinking weeks 2-3 compared to all other groups and compared to SS and ISO groups in week 4. For the female cohort, we did not observe consistent group differences in anxiety-like behavior, CORT levels were unexpectedly lower in the ISO group only compared to the other groups, and group differences were not apparent for ethanol intake/preference. In conclusion, chronic stress during adolescence in the form of social instability increases anxiety-like behavior and ethanol preference in male rats, consistent with other models of

In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed Evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E-deficient mice.

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Yasuda, Satoshi; Ikuta, Kenjiro; Uwatoku, Toyokazu; Oi, Keiji; Abe, Kohtaro; Hyodo, Fuminori; Yoshimitsu, Kengo; Sugimura, Kohtaro; Utsumi, Hideo; Katayama, Yoshiki; Shimokawa, Hiroaki

2008-01-01

Magnetic resonance imaging (MRI) contrast agents that specifically detect atherosclerotic plaque may be useful for the noninvasive detection of the plaque. We have recently developed a new contrast agent, Evans blue-DTPA-gadolinium (EB-DTPA-Gd), which selectively accumulates vascular lesions with endothelial removal. In this study, we examined whether EB-DTPA-Gd is also useful for in vivo imaging of atherosclerotic plaques. We used male apolipoprotein-E-deficient (ApoE-/-) mice of different ages (3, 6 and 12 months old) and age-matched male wild-type mice. After a single intravenous administration of EB-DTPA-Gd (160 microM/kg body weight), MRI T(1) signal was obtained in vivo. Increased signal intensity in the aortic wall was noted within 10-20 min after intravenous injection of EB-DTPA-Gd and was maintained for 30 min. The MRI enhancement in the aorta of ApoE-/- mice was increased in accordance with age, whereas no such enhancement was noted in wild-type mice. Histological examination demonstrated that there was a topological correlation between the site of MRI enhancement and that of atherosclerotic plaque. These results indicate that EB-DTPA-Gd is a useful MRI contrast medium for the in vivo detection of atherosclerotic plaques. Copyright (c) 2007 S. Karger AG, Basel.

Reduced hippocampal dendritic spine density and BDNF expression following acute postnatal exposure to di(2-ethylhexyl phthalate in male Long Evans rats.

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Catherine A Smith

Full Text Available Early developmental exposure to di(2-ethylhexyl phthalate (DEHP has been linked to a variety of neurodevelopmental changes, particularly in rodents. The primary goal of this work was to establish whether acute postnatal exposure to a low dose of DEHP would alter hippocampal dendritic morphology and BDNF and caspase-3 mRNA expression in male and female Long Evans rats. Treatment with DEHP in male rats led to a reduction in spine density on basal and apical dendrites of neurons in the CA3 dorsal hippocampal region compared to vehicle-treated male controls. Dorsal hippocampal BDNF mRNA expression was also down-regulated in male rats exposed to DEHP. No differences in hippocampal spine density or BDNF mRNA expression were observed in female rats treated with DEHP compared to controls. DEHP treatment did not affect hippocampal caspase-3 mRNA expression in male or female rats. These results suggest a gender-specific vulnerability to early developmental DEHP exposure in male rats whereby postnatal DEHP exposure may interfere with normal synaptogenesis and connectivity in the hippocampus. Decreased expression of BDNF mRNA may represent a molecular mechanism underlying the reduction in dendritic spine density observed in hippocampal CA3 neurons. These findings provide initial evidence for a link between developmental exposure to DEHP, reduced levels of BDNF and hippocampal atrophy in male rats.

New Perspectives for Old Clusters: Anderson-Evans Anions as Building Blocks of Large Polyoxometalate Frameworks in a Series of Heterometallic 3 d-4 f Species.

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Artetxe, Beñat; Reinoso, Santiago; San Felices, Leire; Lezama, Luis; Gutiérrez-Zorrilla, Juan M; Vicent, Cristian; Haso, Fadi; Liu, Tianbo

2016-03-18

A series of nine [Sb7W36O133Ln3M2(OAc)(H2O)8](17-) heterometallic anions (Ln3M2; Ln=La-Gd, M=Co; Ln=Ce, M=Ni and Zn) have been obtained by reacting 3 d metal disubstituted Krebs-type tungstoantimonates(III) with early lanthanides. Their unique tetrameric structure contains a novel {MW9O33} capping unit formed by a planar {MW6O24} fragment to which three {WO2} groups are condensed to form a tungstate skeleton identical to that of a hypothetical trilacunary derivative of the ɛ-Keggin cluster. It is shown, for the first time, that classical Anderson-Evans {MW6O24} anions can act as building blocks to construct purely inorganic large frameworks. Unprecedented reactivity in the outer ring of these disk-shaped species is also revealed. The Ln3M2 anions possess chirality owing to a {Sb4O4} cluster being encapsulated in left- or right-handed orientations. Their ability to self-associate in blackberry-type vesicles in solution has been assessed for the Ce3Co2 derivative. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Decreased sexual motivation and heightened anxiety in male Long-Evans rats are correlated with the memory for a traumatic event.

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Hawley, Wayne R; Grissom, Elin M; Belkin, Mark N; James, Thomas F; Dohanich, Gary P

2013-05-01

Individuals suffering from posttraumatic stress disorder (PTSD) frequently report disturbances in sexual functioning in addition to alterations in their affective behaviors. Notably, maladaptive cognitions and dysfunctional behaviors are perpetuated by the emergence of the intrusive thoughts that characterize the disorder. In rats, reminders of a traumatic event designed to simulate intrusive thoughts are associated with impairments in affective, social, and sexual behaviors. The current study examined the relationship between the memory for a traumatic event and changes in sexual and affective behaviors in male Long-Evans rats (N = 36). The trauma featured a combination stressor consisting of simultaneous exposure to a footshock and the odor of soiled cat litter. Memory for the trauma was reactivated by re-exposures to the context of the trauma in the absence of stressors and confirmed by assessing the percentage of time spent freezing. Following the second and final reminder, traumatized males exhibited reduced sexual motivation and increased anxiety, signified by longer latencies to achieve their first mount on a post-stress test of sexual behavior, and longer latencies to begin feeding in a novel environment, respectively. Correlational analyses revealed that decreased sexual motivation and heightened anxiety were predicted by the memory for the trauma as indicated by the time spent freezing during the re-exposures. The findings from the current study have implications for understanding the relationship between stress and sexual functioning and indicate that the impairments in sexual behavior that often occur in individuals with PTSD may be impacted by their memory for the trauma.

Konflikte otsides edu ei saavuta / Jacek Protasiewicz, Tadeusz Zwiefka

Index Scriptorium Estoniae

Protasiewicz, Jacek

2008-01-01

Poola Euroopa Parlamendi saadikute hinnangul põhjustasid Poola 2007. aasta parlamendivalimiste kõrge valimisaktiivsuse üldine vastuseis pidevatele konfliktidele nii valitsuses kui opositsioonis, negatiivne suhtumine radikaalse koalitsiooni poolt teostatavasse rahvusvahelisse poliitikasse ning strateegia puudumine, millega saaks valitsus takistada noorte poolakate suurt töörännet Ühendkuningriiki ja Iirimaale

Identification of a Major Locus Contributing to Erythrocyte 2,3-Diphosphoglycerate Variability in Hooded (Long-Evans) Rats

Science.gov (United States)

Noble, N. A.; Brewer, G. J.

1977-01-01

The erythrocyte glycolytic intermediate 2,3-diphosphoglycerate (DPG) and adenosine triphosphate (ATP) play an important role in oxygen transport and delivery by binding to hemoglobin (Hb) and reducing its affinity for oxygen. Considerable quantitative variability in the levels of DPG and ATP exists in human populations and in a population of hooded (Long-Evans) rats we have studied. This paper presents the results of studies on the genetic component of DPG-level variation in an outbred population of hooded rats. Beginning with about 100 rats, a two-way selection experiment was initiated. Pairs of rats with the highest DPG levels were mated to produce a High-DPG rat strain and animals with the lowest DPG levels were mated to produce a Low-DPG strain. Mean DPG levels responded rapidly to selection and, from generation 3 on, the differences between strain means were highly significant. Ten High-DPG strain rats were intercrossed with 10 Low-DPG strain rats of generation 10 to produce an F1 generation in which the DPG levels were almost as high as those of High-DPG animals. This indicates partial dominance of High-DPG alleles. The F2 DPG-level distribution showed two distinct subpopulations. The high DPG subpopulation contained three times as many animals as the low DPG subpopulation. From these results and the statistical analyses performed, it was concluded that the DPG differences between strains were due to an allelic difference at one major locus, the allele carried by the High-DPG strain showing partial dominance over the allele carried by the Low-DPG strain. It appears that this locus may also effect ATP levels to a large extent and is polymorphic in hooded rat populations. Identification of this locus gives us a useful tool for studies of the physiological effects of DPG variability, as well as providing an example of a major gene effect in a quantitatively varying trait. PMID:863239

Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats

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Bu Lihong

2004-12-01

Full Text Available Abstract Background Phytoestrogens derived from soy foods (or isoflavones have received prevalent usage due to their 'health benefits' of decreasing: a age-related diseases, b hormone-dependent cancers and c postmenopausal symptoms. However, little is known about the influence of dietary phytoestrogens on regulatory behaviors, such as food and water intake, metabolic hormones and neuroendocrine parameters. This study examined important hormonal and metabolic health issues by testing the hypotheses that dietary soy-derived isoflavones influence: 1 body weight and adipose deposition, 2 food and water intake, 3 metabolic hormones (i.e., leptin, insulin, T3 and glucose levels, 4 brain neuropeptide Y (NPY levels, 5 heat production [in brown adipose tissue (BAT quantifying uncoupling protein (UCP-1 mRNA levels] and 6 core body temperature. Methods This was accomplished by conducting longitudinal studies where male Long-Evans rats were exposed (from conception to time of testing or tissue collection to a diet rich in isoflavones (at 600 micrograms/gram of diet or 600 ppm vs. a diet low in isoflavones (at approximately 10–15 micrograms/gram of diet or 10–15 ppm. Body, white adipose tissue and food intake were measured in grams and water intake in milliliters. The hormones (leptin, insulin, T3, glucose and NPY were quantified by radioimmunoassays (RIA. BAT UCP-1 mRNA levels were quantified by PCR and polyacrylamide gel electrophoresis while core body temperatures were recorded by radio telemetry. The data were tested by analysis of variance (ANOVA (or where appropriate by repeated measures. Results Body and adipose tissue weights were decreased in Phyto-600 vs. Phyto-free fed rats. Food and water intake was greater in Phyto-600 animals, that displayed higher hypothalamic (NPY concentrations, but lower plasma leptin and insulin levels, vs. Phyto-free fed males. Higher thyroid levels (and a tendency for higher glucose levels and increased uncoupling

Inactivating the infralimbic but not prelimbic medial prefrontal cortex facilitates the extinction of appetitive Pavlovian conditioning in Long-Evans rats.

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Mendoza, J; Sanio, C; Chaudhri, N

2015-02-01

The infralimbic medial prefrontal cortex (IL) has been posited as a common node in distinct neural circuits that mediate the extinction of appetitive and aversive conditioning. However, appetitive extinction is typically assessed using instrumental conditioning procedures, whereas the extinction of aversive conditioning is customarily studied using Pavlovian assays. The role of the IL in the extinction of appetitive Pavlovian conditioning remains underexplored. We investigated the involvement of the IL and prelimbic medial prefrontal cortex (PrL) in appetitive extinction in Pavlovian and instrumental conditioning assays in male, Long-Evans rats. Following acquisition, a gamma-aminobutyric acid agonist solution (0.03 nmol muscimol; 0.3 nmol baclofen; 0.3 μl/side) was bilaterally microinfused into the IL or PrL to pharmacologically inactivate each region before the first extinction session. Compared to saline, PrL inactivation did not affect the acquisition of extinction or the recall of extinction memory 24-h later. IL inactivation caused a more rapid extinction of Pavlovian conditioning, but had no effect on the extinction of instrumental conditioning or extinction recall. IL inactivation during a Pavlovian conditioning session in which conditioned stimulus (CS) trials were paired with sucrose did not affect CS-elicited behaviour, but increased responding during intervals that did not contain the CS. The same manipulation did not impact lever pressing for sucrose. These findings suggest that the IL may normally maintain Pavlovian conditioned responding when an anticipated appetitive CS is unexpectedly withheld, and that this region has distinct roles in the expression of Pavlovian conditioning when an appetitive unconditioned stimulus is either presented or omitted. Copyright © 2014 Elsevier Inc. All rights reserved.

Motor performance of preschool children

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Słonka Karina; Dyas Manuela; Słonka Tadeusz; Szurmik Tomasz

2017-01-01

Słonka Karina, Dyas Manuela, Słonka Tadeusz, Szurmik Tomasz. Motor performance of preschool children. Journal of Education, Health and Sport. 2017;7(8):1308-1323. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1045272 http://ojs.ukw.edu.pl/index.php/johs/article/view/5028 https://pbn.nauka.gov.pl/sedno-webapp/works/836989 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017...

Revision of the Dysmorphoptilidae (Hemiptera: Cicadomorpha: Prosboloidea) of the Queensland Triassic-Part 2.

Science.gov (United States)

Lambkin, Kevin J

2016-03-15

The extinct hemipteran family Dysmorphoptilidae was a major component of the Triassic insect fauna of Queensland preserved at the Denmark Hill, Dinmore, Mount Crosby and Gayndah fossil insect sites. A total of 13 species have now been identified, of which eight species in five genera were examined in the first part of this revision. This second part revises the remaining five species in three genera. Eoscartoides Evans, 1956 (= Mesonirvana Evans, 1956, syn. nov.), comprising Eoscartoides bryani Evans, 1956 (= Mesonirvana abrupta Evans, 1956, syn. nov.) (Mount Crosby), Eoscartoides orthocladus (Tillyard, 1922) comb. nov. (Denmark Hill), and Eoscartoides dmitryi sp. nov. (Dinmore), is distinguished by a strongly developed arc-like strigil in the basal costal space, a very short stem of RA, and a deeply forked M1+2. The monotypic Eoscarterella Evans, 1956, with type species Eoscarterella media Evans, 1956 (Mount Crosby), has a strongly lobate tegmen with peculiar surface sculpture and M1+2 simple. Eoscartoides and Eoscarterella differ from most dysmorphoptilids in having more or less lobate tegmina with even margins (without the antero-apical emargination so typical of the family), as well as the early entry of RA1 into the costal margin and the associated extensive and antero-apically positioned RA2. These characters are also shared with two other dysmorphoptilids, the Australian Permian Belmontocarta Evans and an unnamed Triassic species from Kyrgyzstan, and the four thus form a distinct subgroup within the family. On the other hand, the monotypic Trifidella Evans, 1956 (= Alotrifidus Evans, 1956, syn. nov.), with type species Trifidella perfecta Evans, 1956 (= Alotrifidus interruptus Evans, 1956, syn. nov.) (Mount Crosby), is a more typical dysmorphoptilid with a distinct emargination, RA entering the margin much more apically, and RA2 of limited extent. Trifidella is presumably the sister of the Queensland Triassic Dysmorphoptiloides Evans, sharing the basal

Interrelationships of Prenatal and Postnatal Growth, Hormones, Diet, and Breast Cancer

Science.gov (United States)

2006-03-01

infants to investigate the association between maternal age, diet, preeclampsia , and infant birth weight, and hormone levels using the infants’ cord... etiology of breast cancer. Br J Cancer 1983;47:757–62. 31. Wang CC, Vittinghoff E, Hua LS, Yun WH, Rong KM. Reducing pregnancy and induced abortion...the etiology of oral and pharyngeal cancer among women from the Southern United States. Cancer Res. 1984; 44: 1216–22. 8 Franco EL, Kowalski LP

Lumbar paravertebral blockade as intractable pain management method in palliative care

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Zaporowska-Stachowiak I; Kotlinska-Lemieszek A; Kowalski G; Kosicka K; Hoffmann K; Główka F; Łuczak J

2013-01-01

Iwona Zaporowska-Stachowiak,1,2 Aleksandra Kotlinska-Lemieszek,3 Grzegorz Kowalski,3 Katarzyna Kosicka,4 Karolina Hoffmann,5 Franciszek Główka,4 Jacek Łuczak2 1Department of Pharmacology, 2Palliative Medicine In-patient Unit, University Hospital of Lord’s Transfiguration, 3Department of Palliative Care, 4Department of Physical Pharmacy and Pharmacokinetics, 5Department of Internal Medicine, Metabolic Disorders and Arterial Hypertension, Poznan University of Medical Scie...

Tadeusz Kantori taaskehastumus animeeritud heterotoopiates / Ester Võsu, Pille Jänes

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Võsu, Ester

2006-01-01

Nukufilm "Laud" : stsenaristid, režissöörid, kunstnikud Jelena Girlin ning Mari-Liis Bassovskaja : operaator ja kaasrežissöör Urmas Jõemees : helilooja Malle Maltis : produtsent Arvo Nuut : Nukufilm, 2004. Lisatud andmed autorite ja režissööride kohta lk. 107

Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet

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Karatayev, Olga; Lukatskaya, Olga; Moon, Sang-Ho; Guo, Wei-Ran; Chen, Dan; Algava, Diane; Abedi, Susan; Leibowitz, Sarah F.

2015-01-01

Clinical studies demonstrate frequent co-existence of nicotine and alcohol abuse and suggest that this may result, in part, from the ready access to and intake of fat-rich diets. Whereas animal studies show that high-fat diet intake in adults can enhance the consumption of either nicotine or ethanol and that maternal consumption of a fat-rich diet during pregnancy increases operant responding for nicotine in offspring, little is known about the impact of dietary fat on the co-abuse of these two drugs. The goal of this study was to test in Long-Evans rats the effects of perinatal exposure to fat on the co-use of nicotine and ethanol, using a novel paradigm that involves simultaneous intravenous (IV) self-administration of these two drugs. Fat- vs. chow-exposed offspring were characterized and compared, first in terms of their nicotine self-administration behavior, then in terms of their nicotine/ethanol self-administration behavior, and lastly in terms of their self-administration of ethanol in the absence of nicotine. The results demonstrate that maternal consumption of fat compared to low-fat chow during gestation and lactation significantly stimulates nicotine self-administration during fixed-ratio testing. It also increases nicotine/ethanol self-administration during fixed-ratio and dose-response testing, with BEC elevated to 120 mg/dL, and causes an increase in breakpoint during progressive ratio testing. Of particular note is the finding that rats perinatally exposed to fat self-administer significantly more of the nicotine/ethanol mixture as compared to nicotine alone, an effect not evident in the chow-control rats. After removal of nicotine from the nicotine/ethanol mixture, this difference between the fat- and chow-exposed rats was lost, with both groups failing to acquire the self-administration of ethanol alone. Together, these findings suggest that perinatal exposure to a fat-rich diet, in addition to stimulating self-administration of nicotine, causes

Impression management and self-presentation dissimulation in Portuguese chairman's statements

OpenAIRE

Oliveira, J.; Azevedo, G.; Borges, F.

2016-01-01

WOS:000381979800008 (Nº de Acesso Web of Science) Drawn on social psychology theory of impression management, the present study tries to assess the way Portuguese managers build their narratives in Chairman’s Statement to manage stakeholders’ perceptions on corporate image, in a period of time of scarce resources. The paper’s theoretical framework draws on elements of social psychology theory of impression management developed by Leary and Kowalski (1990). Through the use of the two-compon...

International Symposium on Molecular Beams (14th) Held in Pacific Grove, California on June 7 -12, 1992.

Science.gov (United States)

1993-08-09

frequency domain, molecular probes of quantum clusters, size dependence of elemental clusters, bouncing gases off liquid surfaces, high resolution UV...Photophysique Univ. of California, Berkeley Via S. Loja - Zoma du CNRS, Batiment 213 Berkeley, CA Industriale Di Tito Scalo Universit6 de Paris-Sud 94720...Chair 8:15 M.E. King, S.T. Govoni, M.E. Saecker, D.V. Kowalski, M. Hanning-Le., T.K. Minton and G.M. Nathanson, Bouncing Gases off Liquid Surfaces 8:45

Surgical treatment of GERD. Comperative study of WTP vs. Toupet fundoplication - results of 151 consecutive cases.

Science.gov (United States)

Wróblewski, Tadeusz; Kobryn, Konrad; Nowosad, Małgorzata; Krawczyk, Marek

2016-01-01

Gastroesophageal reflux disease (GERD) is recognized as one of the most common disorders of the upper gastrointestinal tract (GIT). The best choice of management for advanced GERD is laparoscopic surgery. To compare and evaluate the results of surgical treatment of GERD patients operated on using two different techniques. Between 2001 and 2012, 353 patients (211 female and 142 male), aged 17-76 years (mean 44), underwent laparoscopic antireflux surgery. The study included patients who underwent a Toupet fundoplication or Wroblewski Tadeusz procedure (WTP). The mean age of the group was 47.77 years (17-80 years). Forty-nine (32.45%) patients had severe symptoms, 93 (61.58%) had mild symptoms and 9 (5.96%) had a single mild but intolerable sign of GERD. Eighty-six (56.95%) patients had a Toupet fundoplication and 65 (43.04%) had a WTP. The follow-up period was 18-144 months. The average operating time for Toupet fundoplication and the WTP procedure was 164 min (90-300 min) and 147 min (90-210 min), respectively. The perioperative mortality rate was 0.66%. The average post-operative hospitalization period was 5.4 days (2-16 post-operative days (POD) = Toupet) vs. 4.7 days (2-9 POD = WTP). No reoperations were performed. No major surgical complications were identified. Wroblewski Tadeusz procedure due to a low percentage of post-operative complications, good quality of life of patients and a zero recurrence rate of hiatal hernia should be a method of choice.

El polisulfuro de calcio en el manejo de la moniliasis Moniliophthora roreri (Cif & Par. Evans et al. del cacao Theobroma cacao L.

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Sandra Ramírez González

2011-05-01

Full Text Available El cacao es severamente afectado por el hongo Moniliophthora roreri (Cif & Par. Evans et al., el cual daña los frutos y puede ocasionar pérdidas totales y su control es principalmente cultural. El objetivo del trabajo es determinar la efectividad del polisulfuro de calcio (PC como alternativa para su manejo. El patógeno fue aislado y cultivado in vitro y se evaluó el efecto del PC sobre la germinación y formación de conidias; en el campo, sobre frutos se asperjó PC antes y después de la inoculación con M. roreri y se determinó la incidencia e índices de severidad interna y externa. En una plantación de cacao se asperjó PC y se determinó su incidencia y producción. El PC in vitro inhibió el crecimiento y la formación de conidias; la aplicación de PC antes o después de la inoculación artificial con M. roreri sobre frutos inhibe completamente el desarrollo de la enfermedad; con aspersiones de PC en plantaciones de cacao la incidencia de la enfermedad fue de 0,53%, mientras que fue de 21% con manejo cultural y del 69,6% con testigo de inoculación natural; la producción de cacao seco/año fue de un 90,6% más con PC que en el testigo de inoculación natural, por lo que resulta viable integrar PC en el manejo deM. roreri.

Comparison of the enhancement of plasma glucose levels in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats by oral administration of sucrose or maple syrup.

Science.gov (United States)

Nagai, Noriaki; Ito, Yoshimasa; Taga, Atsushi

2013-01-01

Maple syrup is used as a premium natural sweeter, and is known for being good for human health. In the present study, we investigate whether maple syrup is suitable as a sweetener in the management of type 2 diabetes using Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type 2 diabetes mellitus. OLETF rats develop type 2 diabetes mellitus by 30 weeks of age, and 60-week-old OLETF rats show hyperglycemia and hypoinsulinemia via pancreatic β-cell dysfunction. The administration of sucrose or maple syrup following an OGT test increased plasma glucose (PG) levels in OLETF rats, but the enhancement in PG following the oral administration of maple syrup was lower than in the case of sucrose administration in both 30- and 60-week-old OLETF rats. Although, the insulin levels in 30-week-old OLETF rats also increased following the oral administration of sucrose or maple syrup, no increase in insulin levels was seen in 60-week-old OLETF rats following the oral administration of either sucrose or maple syrup. No significant differences were observed in insulin levels between sucrose- and maple syrup-administered OLETF rats at either 30 or 60 weeks of age. The present study strongly suggests that the maple syrup may have a lower glycemic index than sucrose, which may help in the prevention of type 2 diabetes.

Wspólna twarz – Różewicz, Rembrandt i starość

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Rosales Rodriguez, Agnieszka

2014-01-01

This article proposes an interpretation of Rembrandt’s Self-Portrait as Zeuxis Laughing (Wallraf- -Richartz Museum, Cologne) as it appears in Tadeusz Różewicz’s poem Mirror. The 17th-century Dutch artist was known as a painter who portrayed the human body as it really is, i.e. with all its imperfections and changes that are brought about by the passage of time. He has also been regarded as a master who expressed the disappearance and decay of form (Simmel) and the anticipation of death (Malra...

Sinopse das espécies neotropicais do grupo brasiliensis do gênero Apenesia (Hymenoptera, Bethylidae Synopsis of neotropical species of brasiliensis group genus Apenesia (Hymenoptera, Bethylidae

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Magno S Ramos

2009-12-01

Full Text Available São descritas e ilustradas Apenesia longa sp. nov., A. peccata sp. nov., A. magna sp. nov., A. permaxima sp. nov., A. perconcava sp. nov. e A. recta sp. nov. da região Neotropical. São adicionados dados novos de variações estruturais e distribuição geográfica de A. transversa Evans, 1963, A. spinipes Evans, 1969, A. tlahuicana Evans, 1963, A. triangula Azevedo & Batista, 2002, A. megaventris Azevedo & Batista, 2002, A. venezuelana Evans, 1963, A. acia Lanes & Azevedo, 2004 e A. ventosa Azevedo & Batista, 2002. Duas sinonímias novas são propostas: A. peruana Evans, 1963 como sinônimo junior de A. brasiliensis (Kieffer, 1910; A. subangulata Azevedo & Batista, 2002 como sinônimo junior de A. fulvicollis (Westwood, 1874, esta ultima considerada dentro ao grupo nitida. É fornecida uma chave de identificação para as espécies do grupo, baseada em machos.Apenesia longa sp. nov., A. peccata sp. nov., A. magna sp. nov., A. permaxima sp. nov., A. perconcava sp. nov., and A. recta sp. nov., from Neotropical region are described and illustrated. Additional material of A. transversa Evans, 1963, A. spinipes Evans, 1969, A. tlahuicana Evans, 1963, A. triangula Azevedo & Batista, 2002, A. megaventris Azevedo & Batista, 2002, A. venezuelana Evans, 1963, A. acia Lanes & Azevedo, 2004 and A. ventosa Azevedo & Batista, 2002 had their structural variations and known distribution broadened. Two new synonyms are proposed: A. peruana Evans, 1963 as junior synonym of A. brasiliensis (Kieffer, 1910; A. subangulata Azevedo & Batista, 2002 as junior synonym of A. fulvicollis (Westwood, 1874, and the latter considered in the nitida group. An identification key to species of the group based on males is provided.

The bilingual Loch Ness Monster raises its non-asymmetric head again-or, why bother with such cumbersome notions as validity and reliability? Comments on Evans et al. (2000).

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Paradis, Michel

2003-12-01

All of the experimental studies of the past 25 years combined and the meta-analyses of their findings have not advanced our knowledge of the lateralization of language in bilingual speakers one bit. We are left with a clutter of inherently uninterpretable contradictory results. Successive studies do not contribute a single brick to the edifice or a single piece to the puzzle-only more confusion. study is no exception. So far, there has been no demonstration of the validity of any experimental paradigm claiming to measure degree of language laterality in bilingual speakers. Experimentation is pointless unless the nature of what is alleged to be lateralized is clearly defined and the validity of the measures employed has been established. Because of the lack of validity of the paradigms used in bilingual laterality studies, experiments and meta-analyses of their findings cannot have any scientific significance. Like their predecessors, Evans et al. pay lip service to a number of methodological problems, but ignore their implications and simply carry on anyway. The authors ought to demonstrate, rather than assume, that degree of visual half-field advantage for single words corresponds to degree of lateralization of any component of language (even if only of words).

A new species of Dermopristis Kearn, Whittington & Evans-Gowing, 2010 (Monogenea: Microbothriidae), with observations on associations between the gut diverticula and reproductive system and on the presence of denticles in the nasal fossae of the host Glaucostegus typus (Bennett) (Elasmobranchii: Rhinobatidae).

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Whittington, Ian D; Kearn, Graham C

2011-09-01

Dermopristis cairae n. sp. (Monogenea: Microbothriidae) is described from the skin and possibly from the nasal fossae of the giant shovel-nosed ray Glaucostegus typus (Bennett). The new species is distinguished from D. paradoxus Kearn, Whittington & Evans-Gowing, 2010 by its larger size, body shape, lack of transverse ridges on the ventral surface and absence of a seminal receptacle. Extensive short gut branches lie dorsal to the testes and adjacent to the coiled region of the vas deferens and the oötype, possibly reflecting high metabolic demand in these areas. Denticles are present in the lining of the nasal fossae of G. typus, providing a firm substrate for the cement-based attachment of a microbothriid. However, confirmation that D. cairae inhabits the nasal fossae of G. typus is required.

An iron-deficient diet stimulates the onset of the hepatitis due to hepatic copper deposition in the Long-Evans Cinnamon (LEC) rat

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Sugawara, Naoki; Sugawara, Chieko [Sapporo Medical Univ. (Japan). Dept. of Public Health

1999-09-01

To study effects of dietary Cu and Fe levels on the onset of hepatitis in Long-Evans Cinnamon (LEC) rats, female rats (40 days old) were fed a semipurified diet containing 0.1 or 10 mg Cu/kg and 1.5 or 150 mg Fe/kg in a 2 x 2 factorial arrangement for 35 days. At 75 days after birth, LEC rats (+Cu-Fe) fed a Cu-sufficient but Fe-deficient diet (Cu, 10 mg/kg; Fe, 1.5 mg/kg) showed jaundice, with lethargy, anorexia, and malaise. The biochemical variables relating to liver function were significantly increased compared to three other groups, a Cu- and Fe-deficient (-Cu-Fe) group, a Cu-deficient but Fe-sufficient (-Cu+Fe) group, and a Cu and Fe sufficient (+Cu+Fe) group. Furthermore, the +Cu-Fe rat liver showed massive necrosis with huge nuclei. The other three groups presented no biochemical and histological findings of hepatitis. Hepatic Cu and metallothionein concentrations were 289 {+-} 87 (mean {+-} SD) {mu}g/g liver and 8.7 {+-} 1.8 mg/g liver, respectively, in the +Cu-Fe rats. However, in the +Cu+Fe group the values were 196 {+-} 28 {mu}g Cu/g liver and 10.8 {+-} 1.0 mg/g liver. Hepatic Fe deposition was not influenced significantly by the dietary Cu level. The +Cu-Fe group with jaundice showed the highest free Cu concentration in the liver among the four groups, but the hepatic free Fe concentration was similar to those in the -Cu+Fe and +Cu+Fe groups. Our results indicate that an Fe-deficient diet enhances the deposition of hepatic Cu due to increased absorption of Cu from the gastrointestinal tract. This deposition stimulated the onset of hepatitis. (orig.)

Ten Good Reasons for the Use of the Tellurium-Centered Anderson-Evans Polyoxotungstate in Protein Crystallography.

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Bijelic, Aleksandar; Rompel, Annette

2017-06-20

Protein crystallography represents at present the most productive and most widely used method to obtain structural information on target proteins and protein-ligand complexes within the atomic resolution range. The knowledge obtained in this way is essential for understanding the biology, chemistry, and biochemistry of proteins and their functions but also for the development of compounds of high pharmacological and medicinal interest. Here, we address the very central problem in protein crystallography: the unpredictability of the crystallization process. Obtaining protein crystals that diffract to high resolutions represents the essential step to perform any structural study by X-ray crystallography; however, this method still depends basically on trial and error making it a very time- and resource-consuming process. The use of additives is an established process to enable or improve the crystallization of proteins in order to obtain high quality crystals. Therefore, a more universal additive addressing a wider range of proteins is desirable as it would represent a huge advance in protein crystallography and at the same time drastically impact multiple research fields. This in turn could add an overall benefit for the entire society as it profits from the faster development of novel or improved drugs and from a deeper understanding of biological, biochemical, and pharmacological phenomena. With this aim in view, we have tested several compounds belonging to the emerging class of polyoxometalates (POMs) for their suitability as crystallization additives and revealed that the tellurium-centered Anderson-Evans polyoxotungstate [TeW 6 O 24 ] 6- (TEW) was the most suitable POM-archetype. After its first successful application as a crystallization additive, we repeatedly reported on TEW's positive effects on the crystallization behavior of proteins with a particular focus on the protein-TEW interactions. As electrostatic interactions are the main force for TEW binding

Surgical treatment of GERD. Comperative study of WTP vs. Toupet fundoplication – results of 151 consecutive cases

Directory of Open Access Journals (Sweden)

Tadeusz Wróblewski

2016-03-01

Full Text Available Introduction: Gastroesophageal reflux disease (GERD is recognized as one of the most common disorders of the upper gastrointestinal tract (GIT. The best choice of management for advanced GERD is laparoscopic surgery. Aim : To compare and evaluate the results of surgical treatment of GERD patients operated on using two different techniques. Material and methods : Between 2001 and 2012, 353 patients (211 female and 142 male, aged 17–76 years (mean 44, underwent laparoscopic antireflux surgery. The study included patients who underwent a Toupet fundoplication or Wroblewski Tadeusz Procedure (WTP. Results: The mean age of the group was 47.77 years (17–80 years. Forty-nine (32.45% patients had severe symptoms, 93 (61.58% had mild symptoms and 9 (5.96% had a single mild but intolerable sign of GERD. Eighty-six (56.95% patients had a Toupet fundoplication and 65 (43.04% had a WTP. The follow-up period was 18–144 months. The average operating time for Toupet fundoplication and the WTP procedure was 164 min (90–300 min and 147 min (90–210 min, respectively. The perioperative mortality rate was 0.66%. The average post-operative hospitalization period was 5.4 days (2–16 post-operative days (POD = Toupet vs. 4.7 days (2–9 POD = WTP. No reoperations were performed. No major surgical complications were identified. Conclusions : Wroblewski Tadeusz Procedure due to a low percentage of post-operative complications, good quality of life of patients and a zero recurrence rate of hiatal hernia should be a method of choice.

Taxonomia de Bakeriella (Hymenoptera, Bethylidae da Bolívia Taxonomy of Bakeriella (Hymenoptera, Bethylidae from Bolivia

Directory of Open Access Journals (Sweden)

Celso O. Azevedo

Full Text Available A fauna de Bakeriella da Bolívia é analisada taxonomicamente. Bakeriella bulbosa Azevedo & Moreira sp. nov., B. labans Azevedo & Moreira sp. nov., B. vicina Azevedo & Moreira sp. nov., B. absens Kawada & Azevedo sp. nov. e B. nuda Kawada & Azevedo sp. nov. são descritas e ilustradas. Novos registros geográficos e dados de variações de B. montivaga (Kieffer, 1910, B. reclusa (Evans, 1969, B. incompleta Azevedo, 1994, B. inca Evans, 1964, B. polita Evans, 1964, B. flavicornis Kieffer, 1910 e B. lata Kawada & Azevedo, 2003 são fornecidos.The Bakeriella fauna from Bolivia is taxonomically analyzed. Bakeriella bulbosa Azevedo & Moreira sp. nov., B. labans Azevedo & Moreira sp. nov., B. vicina Azevedo & Moreira sp. nov., B. absens Kawada & Azevedo sp. nov. and B. nuda Kawada & Azevedo sp. nov. are described and illustrated. New geographic records and variation data of B. montivaga (Kieffer, 1910, B. reclusa (Evans, 1969, B. incompleta Azevedo, 1994, B. inca Evans, 1964, B. polita Evans, 1964, B. flavicornis Kieffer, 1910 and B. lata Kawada & Azevedo, 2003 are provided.

Dr Luigi Orlando, Dr Sergio Ceccuzzi, Dr. Armando Sbrana, Europa Metalli, Italy, Dr Albert Scherger, Member of KM Europa Metal AG, Osnabr ck, Germany, Prof. Filippo Menzinger, Scientific Attaché, Permanent Mission of Italy in Geneva

CERN Multimedia

Patrice Loïez

2001-01-01

Photo 01: Dr Lyn Evans and Dr Luigi Orlando Photo 04: L. to r.: Dr Lyn Evans, Dr Luigi Orlando, Prof. Luciano Maiani and Prof. Filippo Menzinger Photo 06: L. to r.: Prof. Philippo Menzinger, Dr Armando Sbrana, Prof. Luciano Maiani, Dr Albert Scherger, Dr Lyn Evans, Dr Luigi Orlando, Dr Sergio Ceccuzzi, visiting the LHC superconducting magnet test hall, SM18

In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning

International Nuclear Information System (INIS)

Gallagher, M.; Bizon, J.L.; Nicolle, M.M.

1996-01-01

Using in vitro autoradiography, we investigated [ 3 H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate, [ 3 H]kainate and [ 3 H]N-methyl-d-aspartate binding in two forebrain regions, the hippocampus and striatum, of young (four months of age) and aged (24-25 months of age) Long-Evans rats that had previously been tested for spatial learning ability in the Morris water maze. Although there was substantial preservation of binding in the aged rats, reductions in binding were present in the aged rats that were specific to ligand and anatomical region. In the hippocampus of aged rats, [ 3 H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate binding in CA1 and [ 3 H]kainate binding in CA3 were reduced. In contrast, N-methyl-d-aspartate binding was not significantly different between age groups. There was evidence of sprouting in the dentate gyrus molecular layer of aged rats, indicated by changes in the topography of [ 3 H]kainate binding. Binding density was analysed with respect to patch/matrix compartmentalization in the striatum. The most striking result was a large decrease in N-methyl-d-aspartate binding in aged rats that was not limited to any dorsal/ventral or patch/matrix area of the striatum. Additionally, [ 3 H]kainate binding in striatal matrix was modestly reduced in aged rats. Of these age effects, only N-methyl-d-aspartate binding in the striatum and [ 3 H]kainate binding in the CA3 region of the hippocampus were correlated with spatial learning, with lower binding in the aged rats associated with better spatial learning ability.Age-related alterations in ionotropic glutamate receptors differ with respect to the receptor subtype and anatomical region examined. The age effects were not neccessarily indicative of cognitive decline, as only two age-related binding changes were correlated with spatial learning. Interestingly, in these instances, lower binding in the aged rats was associated with preserved spatial learning, suggesting a compensatory reduction

Development of Design Standards and Guidelines for Electromagnetic Compatibility and Lightning Protection for Spacecraft Utilizing Composite Materials

Science.gov (United States)

Camp, Dennis W.

1997-01-01

This final report presents information concerning technical accomplishments by Tec-Masters, Inc. (TMI) for this contract effort. This effort included the accomplishment and/or submission by TMI of the following items: (1) Literature Survey Report, Electrical Properties of Non-Metallic Composites by Mr. Hugh W. Denny; (2) Interim Report, Composite Materials - Conductivity, Shielding Effectiveness, and Current Carrying Capability by Mr. Ross W. Evans; (3) Fault Current Test Plan by Mr. Ross W. Evans (4) Fault Current Test Procedure by Mr. Ross W. Evans (5) Test Report, Fault Current Through Graphite Filament Reinforced Plastic, NASA CR-4774, Marshall Space Flight Center, Alabama, September 1996, by Mr. Ross W. Evans; (6) Test Plan, Lightning Effects on Composite Materials by Mr. Ross W. Evans; (7) Test Report, Lightning Effects on Composite Materials, NASA CR-4783, Marshall Space Flight Center, Alabama, February 1997, by Mr. Ross W. Evans; (8) Design Guidelines for Shielding Effectiveness, Current Carrying Capability, and the Enhancement of Conductivity of Composite Materials, NASA CR-4784, Marshall Space Flight Center, Alabama, September 1996, by Mr. Ross W. Evans. These items are not attached but are considered to be a part of this final report. Efforts on two additional items were accomplished at no increase in cost to NASA/MSFC. These items consisted of updating the 'MSFC EMC Design and Interference Control Handbook,' and revising the 'Design Guidelines for Shielding Effectiveness, Current Carrying Capability, and the Enhancement of Conductivity of Composite Materials.'

Relationship between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and disturbance of intermediary metabolism in the Long-Evans rat

Energy Technology Data Exchange (ETDEWEB)

Fan, F. (Dept. of Pharmacology, Toxicology and Therapeutics, Univ. of Kansas Medical Center, Kansas City, KS (United States)); Rozman, K.K. (Section of Environmental Toxicology, GSF-Inst. fuer Toxikologie, Neuherberg (Germany))

1994-12-01

The aim of this study was to examine the acute toxicity of TCDD in a rat strain other than the Sprague-Dawley (S-D) rat. Doses for the biochemical study were selected based on an acute range-finding study, which indicated that Long-Evans (L-E) rats are somewhat less susceptible to TCDD toxicity than are S-D rats. Male L-E rats were dosed orally with 10, 20, 45, 67, 100 and 150 [mu]g/kg TCDD. Body weight and feed intake were dose-dependently decreased prior to killing of the animals. Eight days after dosing, animals were killed and tryptophan, total T[sub 4] (TT[sub 4]) and total T[sub 3] (TT[sub 3]) levels were determined in serum, whereas the activities of ethoxy-resorufin-O-deethylase (EROD), phosphoenolpyruvate carboxykinase (PEPCK), [gamma]-glutamyl transpeptidase ([gamma]-GT) and tryptophan 2,3-dioxygenase (TdO) were measured in liver. EROD activity was fully induced at all doses studied, indicating that as in S-D rats, Ah-receptor-mediated effects do not seem to play any major role in the acute toxicity of TCDD in this rat strain either. Hepatic PEPCK activity was dose-dependently decreased in a similar dose range as in S-D rats, indicating inhibition of gluconeogenesis. Feed intake was dose-dependently decreased as a result of a dose-dependent elevation in serum tryptophan levels, which in turn were related to reduced liver TdO activity. Hepatic [gamma]-GT activity was also dose-dependently reduced. However, unlike in S-D rats, these dose-responses occurred in a higher dose range than the reduction of PEPCK activity which appears to be the explanation for the decreased susceptibility of L-E rats to TCDD. Serum TT[sub 4] levels were significantly decreased at all doses, whereas the serum concentration of TT[sub 3] appeared unaffected. The results of this study suggest that subtle differences in the regulation of intermediary metabolism between these two strains of rats are responsible for strain differences in the susceptibility to TCDD. (orig.)

77 FR 6785 - Proposed Information Collection; Comment Request; List of Gear by Fisheries and Fishery...

Science.gov (United States)

2012-02-09

... to Paula N. Evans (301) 427-8557 or Paula.Evans@noaa.gov . SUPPLEMENTARY INFORMATION: I. Abstract... hours and cost) of the proposed collection of information; (c) ways to enhance the quality, utility, and...

Abiotic versus biotic drivers of ocean pH variation under fast sea ice in McMurdo Sound, Antarctica.

Directory of Open Access Journals (Sweden)

Paul G Matson

Full Text Available Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor. Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only, tide (Cape Evans and New Harbor, and water mass properties (temperature and salinity during spring and early summer 2011. These collective observations showed that (1 pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007 and range of pH (Cape Evans: 0.090; Hut Point: 0.036, and (2 pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes--in this case algal photosynthesis--to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound.

Abiotic versus biotic drivers of ocean pH variation under fast sea ice in McMurdo Sound, Antarctica.

Science.gov (United States)

Matson, Paul G; Washburn, Libe; Martz, Todd R; Hofmann, Gretchen E

2014-01-01

Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula) and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor). Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only), tide (Cape Evans and New Harbor), and water mass properties (temperature and salinity) during spring and early summer 2011. These collective observations showed that (1) pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007) and range of pH (Cape Evans: 0.090; Hut Point: 0.036), and (2) pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes--in this case algal photosynthesis--to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities) to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound.

The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells.

Science.gov (United States)

Yoon, Seolah; Kim, Jeongjun; Lee, Hyunghee; Lee, Haerim; Lim, Jonghoon; Yang, Heejeong; Shin, Soon Shik; Yoon, Michung

2017-01-04

Hepatic steatosis has risen rapidly in parallel with a dramatic increase in obesity. The aim of this study was to determine whether the herbal composition Gambigyeongsinhwan (4) (GGH(4)), composed of Curcuma longa L. (Zingiberaceae), Alnus japonica (Thunb.) Steud. (Betulaceae), and the fermented traditional Korean medicine Massa Medicata Fermentata, regulates hepatic steatosis and inflammation. The effects of GGH(4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty (OLETF) rats and HepG2 cells were examined using Oil red O, hematoxylin and eosin, and toluidine blue staining, immunohistochemistry, quantitative real-time polymerase chain reaction, and peroxisome proliferator-activated receptor α (PPARα) transactivation assay. Administration of GGH(4) to OLETF rats improved hepatic steatosis and lowered serum levels of alanine transaminase, total cholesterol, triglycerides, and free fatty acids. GGH(4) increased mRNA levels of fatty acid oxidation enzymes (ACOX, HD, CPT-1, and MCAD) and decreased mRNA levels of lipogenesis genes (FAS, ACC1, C/EBPα, and SREBP-1c) in the liver of OLETF rats. In addition, infiltration of inflammatory cells and expression of inflammatory cytokines (CD68, TNFα, and MCP-1) in liver tissue were reduced by GGH(4). Treatment of HepG2 cells with a mixture of oleic acid and palmitoleic acid induced significant lipid accumulation, but GGH(4) inhibited lipid accumulation by regulating the expression of hepatic fatty acid oxidation and lipogenic genes. GGH(4) also increased PPARα reporter gene expression. These effects of GGH(4) were similar to those of the PPARα activator fenofibrate, whereas the PPARα antagonist GW6471 reversed the inhibitory effects of GGH(4) on lipid accumulation in HepG2 cells. These results suggest that GGH(4) inhibits obesity-induced hepatic steatosis and that this process may be mediated by regulation of the expression of PPARα target genes and lipogenic genes. GGH(4) also suppressed obesity

Carbon Stars T. Lloyd Evans

Indian Academy of Sciences (India)

that the features used in estimating luminosities of ordinary giant stars are just those whose abundance ... This difference between the spectral energy distributions (SEDs) of CH stars and the. J stars, which belong to .... that the first group was binaries, as for the CH stars of the solar vicinity, while those of the second group ...

Chemistry of Blood Type

Science.gov (United States)

Coleman, William F.

2005-01-01

The molecule of December 2005 comes from the paper by Rose, Palcic and Evans on structural factors determining the blood type. The structure was previously reported by Palcic and Evans and is presented without the water molecule that is determined in the crystal structure.

A computational study on the effect of fracture intrusion distance in three- and four-part trochanteric fractures treated with Gamma nail and sliding hip screw.

Science.gov (United States)

Goffin, Jérôme M; Pankaj, Pankaj; Simpson, A Hamish

2014-01-01

Using finite element analysis, the behaviors of the Gamma nail and the sliding hip screw (SHS) were compared in an osteoporotic bone model for the fixation of three- and four-part trochanteric fractures (31-A2 in the AO classification, types IV and V in Evans' classification). The size of the medial fragment was varied based on clinical data, and the case of a fractured greater trochanter was also considered. Our results showed that for Evans' type V stabilized with a Gamma nail and for Evans' types IV and V with the SHS, cancellous bone around the lag screw is susceptible to yielding, thus indicating a risk of cut-out. The volume of bone susceptible to yielding increases with an increase in size of the medial fragment. Conversely, Evans' type IV with a Gamma nail was not predicted to cut out. Our findings suggest that future clinical trials investigating fixation of unstable proximal fractures should include the size of the medial fragment and the integrity of the greater trochanter as covariables and be powered to evaluate whether intramedullary devices are superior to SHSs for Evans' type IV fractures and inferior/equivalent for type V. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

The Army Enlistment Decision: An Overview of the ARI Recruit Surveys, 1982 and 1983

Science.gov (United States)

1984-06-01

Tom Evans, Deputy Director of Advertising and Sales Promotion at USAREC, was very helpful in providing topic areas and information on advertising and...at the US Army Recruiting Command (USAREC). COL Graf and Mr. Evans, Director and Deputy Director of Advertising and Sales Promotion at USAREC, were

A trendy approach to education!

CERN Document Server

Alizée Dauvergne

2010-01-01

On 11 March, Lyn Evans, the LHC project leader, talked live to hundreds of students in Wales using the standard videoconference equipment available at CERN (see box below). The students were delighted with the presentation and obviously very much appreciated this modern means of communication with the Laboratory. A further lecture is planned for May.   Question time after the videoconference between Lyn Evans and 27 schools and colleges in Wales. The Welsh Video Network (WVN) is one of the most advanced videoconferencing networks in the world, comprising over 80 networked video studios throughout Wales. For the LHC lecture given by Lyn Evans, no fewer than 27 schools and colleges were connected live with CERN. “This was a lecture for A-level students”, says Lyn Evans. “I introduced CERN and spoke about the physics we are doing here and what we want to discover. I talked about antimatter, dark matter, etc.” The LHC lecture was part of the WVN lecture series...

Retirement postponed!

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

As the LHC celebrates a highly successful year so far, the world accelerator community is already looking ahead to the next collider. It has appointed a CERN past master of accelerator building to coordinate the development of future linear collider efforts.   Lyn Evans at SM-18. Lyn Evans, former LHC project leader, has just been appointed director of the new Linear Collider organisation which brings together the two existing linear collider programmes under one roof. “We will initially continue to work in parallel on both CLIC and the ILC,” says Evans. The two proposed accelerators have a number of elements in common, from the damping rings to the final focus systems. Both have very similar detector designs, with the exception of the data acquisition systems as the machines have very different time structures. “The technologies for the two accelerators are at very different levels of maturity,” summarises Evans. When the time comes to make t...

Building bridges … and accelerators

CERN Multimedia

2009-01-01

Lyn Evans, the LHC project leader, was awarded an honorary doctorate from the University of Geneva (UNIGE) to celebrate his role not just in building accelerators, but also in building bridges between nations. He was one of four notables honoured at the event on Friday 5 June, coinciding with the University’s 450th Anniversary. Lyn Evans arriving at the ceremony with Archbishop Desmond Tutu. "It was a big surprise when I found out I’d been nominated," recounts Evans, "but it was an even bigger surprise to find out with whom I’d been nominated". At the ceremony Evans was awarded the honorary doctorate along with three others: Archbishop Desmond Tutu, who was acclaimed for his fight against apartheid in South Africa, Mary Robinson, first woman president of Ireland and former United Nations’ high commissioner of human rights, and Pascal Lamy, Director-General of the World Trade Organization. The award ceremony, known as the �...

Notas sinonímicas sobre Hesperiidae neotropicais, com descrições de novos gêneros, espécies e subespécies (Lepidoptera

Directory of Open Access Journals (Sweden)

Olaf H. H. Mielke

1990-01-01

Full Text Available Celaenorrhinus shema mercedensis, ssp. n. de La Mercede e Rio Colorado, Peru e Cochabamba, Bolívia; Phocides pialia intermedia, ssp. n. de Minas Gerais, Brasil; Corticea diamantina, sp. n. de Minas Gerais, Brasil; Artines tobiasi sp. n. de Minas Gerais, Brasil; Cymaenes albiventris albiventris, sp. n. do Maranhão, Brasil; Cymaenes albiventris capixaba, ssp. n. do Espirito Santo, Brasil; Papias cascatona, sp. n. de Minas Geras, Brasil; Lerema caraca, sp. n. de Minas Gerais e Espirito Santo, Brasil; Vettius ploetzii morretesi, ssp. n. do Paraná e Rio Grande do Sul, Brasil Propapias, gen. n., tipo: Rhinthon proximus Bell, 1934, única espécie incluída. Celaenorrhinus songoensis saroma Evans, 1952, comb. n.; Celaenorrhinus songoensis tonio Evans, 1952, comb. n. Lerema duroca duroca (Ploetz, 1883, comb. n. e sp. rev. Lerema duroca lenta Evans, 1955, stat. n. Eumesia eburones inornata (Bell, 1937, comb. n. e stat. n., Eprius veleda obrepta (Kivirikko, 1936, comb. n. e stat. n., Phocides zancleius 1932 syn. n. de Phocides pialia (Hewitson, 1857; Dalla eburones elna Evans, 1955 syn. n. de Eumesia eburones inornata (Bell, 1937; Staphylus holaphegges Dyar, 1913 syn. n. de Eprius veleda veleda (Godman, 1901; Eprius veleda palta Evans, 1955 syn. n. de Eprius veleda obrepta (Kivirikko, 1936; Lerema elgina Schaus, 1902 syn. n. de Lerema duroca duroca (Ploetz, 1883. Dalla Mabille, 1904 syn. n. de Eumesia Felder &. Felder, 1867, n. rev, Eumesiinae Felder & Felder, 1867, n. rev.Celaenorrhinus shema mercedensis, ssp. n. from La Merced and Rio Colorado, Peru, and Cochabamba, Bolívia; Phocides pialia intermedia, ssp. n. from Minas Gerais, Brazil; Corticea diamantina, sp. n. from Minas Gerais, Brazil; Artines tobiasi, sp. n. from Minas Gerais, Brazil; Cymaenes albiventris albiventris, sp. n. from Maranhão, Brazil; Cymaenes albiventris capixaba, ssp. n. from Espírito Santo, Brazil; Papias cascatona, sp. n. from Minas Gerais, Brazil; Lerema caraca, sp. n. from

Dynamic Written Corrective Feedback in Developmental Multilingual Writing Classes

Science.gov (United States)

Kurzer, Kendon

2018-01-01

This study investigated the role of dynamic written corrective feedback (DWCF; Evans, Hartshorn, McCollum, & Wolfersberger, 2010; Hartshorn & Evans, 2015; Hartshorn et al., 2010), a mode of providing specific, targeted, and individualized grammar feedback in developmental English as a second language (ESL) writing classes (pre-first year…

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African Journals Online (AJOL)

Costallat GL, Appenzeller S, Costallat LT. Evans syndrome and. Systemic Lupus Erythematosus: Clinical presentation and outcome of. Evans syndrome and Systemic Lupus Erythematosus: Clinical pres- entation and outcome: Joint Bone Spine. 2012 Jul;79(4):362-4. Epub. 2011 Sep 23. 8. Greenbaum, Joseph M. McMann, ...

Plasma volume in acute hypoxia

DEFF Research Database (Denmark)

Poulsen, T D; Klausen, T; Richalet, J P

1998-01-01

Exposure to acute hypoxia is associated with changes in body fluid homeostasis and plasma volume (PV). This study compared a dye dilution technique using Evans' blue (PV[Evans']) with a carbon monoxide (CO) rebreathing method (PV[CO]) for measurements of PV in ten normal subjects at sea level...

Pharmacognostic evaluation of the leaves of Dissotis rotundifolia ...

African Journals Online (AJOL)

STORAGESEVER

2009-01-05

Jan 5, 2009 ... Romania, pp.17-25. Evans WC (1996). Trease and Evans Pharmacognosy. WB Saunders. Ltd. London. 14th Ed. 119-159. Harborne JB (1992). Phytochemical methods. A guide to modern technique of plant analysis. Chapman and Hill, London, p. 279. Kokwaro JC (1976). Medicinal plants of East Africa.

A Retrospective, Longitudinal, Claims-Based Comparison of Concomitant Diagnoses Between Individuals with and Without Down Syndrome.

Science.gov (United States)

Kong, Amanda M; Hurley, Dana; Evans, Kristin A; Brixner, Diana; Csoboth, Csilla; Visootsak, Jeannie

2017-07-01

Individuals with Down syndrome (DS) experience various comorbidities in excess of the prevalence seen among the non-DS population. However, the extent of the excess burden of comorbidities specifically within commercially and publicly insured DS populations aged Company, receives payment from Genentech to conduct research, including the research for this study. Truven Health Analytics also receives payment from other pharmaceutical companies to conduct research. Kong and Evans are employed by Truven Health Analytics. Csoboth is employed by Genentech. Brixner reports fees paid to the University of Utah by Truven Health Analytics on her behalf for work related to this study. Hurley reports fees from Genentech for work on this study and for work outside of this study. At the time of this study, Visootsak was employed by F. Hoffman-LaRoche Pharmaceuticals, parent company of Genentech. All authors, including those affiliated with the study sponsor, were involved in the design of the study, interpretation of the data, writing of the manuscript, and the decision to submit the manuscript for publication. Study concept and design were contributed by Kong, Hurley, and Brixner, along with Evans. Kong and Evans collected the data, and data interpretation was performed by Csoboth, Visootsak, Brixner, and Hurley, with assistance from Kong. The manuscript was written by Evans, Kong, Hurley, and Brixner and revised by Kong, Hurley, Evans, and Brixner, with assistance from Csoboth and Visootsak.

Trunnion Rod Microcrack Detection

Science.gov (United States)

2013-08-01

Richard W. Haskins, Joseph A. Padula , and John E. Hite BACKGROUND: Post-tensioned rods are used to anchor spillway gates and transfer the forces...email: James.A.Evans@usace.army.mil). This technical note should be cited as follows: Evans, J. A., Haskins, R. W., Padula , J. A., and Hite, J. E. 2013

Effect of aqueous seed extract of Nigella sativa on lead-induced ...

African Journals Online (AJOL)

It is used in the manufacture of batteries, metal products, paints and other domestic substances. This study investigated the effect of aqueous seed extract of Nigella sativa on leadinduced cerebral cortex toxicity in Long Evan's rats. Twenty five Long Evans rats divided into five groups of five animals were used for the study.

Foster care as a form of family support

Directory of Open Access Journals (Sweden)

Ewa Flaga

2014-12-01

Full Text Available The foster care system in Poland has recently undergone many changes on the basis of new legislation. It has been presented as a part of the work with the child and its family towards reintegration of the child’s family. However, in order for the aim of foster care to be achieved in this form, it is necessary to integrate work with the child and its family with all the elements of the local environment. Similar assumptions are the basis of the pedagogical concept of the environmental educational system by Stanisław Kowalski. The article presents how to implement pedagogical objectives through legal solutions, which emphasize the integration of the local environment.

DFB component production at IHEP complete

CERN Multimedia

2007-01-01

1. LHC project leader Lyn Evans receiving a model of a DFB from IHEP general director Nikolaj Tyurin.2. Collective photo of DFB celebration at IHEP. Participants from left: V. Sytchev, V. Benda, N. Tyurin, A. Zaytcev, L. Evans, A. Perin, R. van Weelderen, Ph. Trilhe, M. Genet, L. Tavian, Ph. Lebrun, A. Kleshov.

It’s no miracle...

CERN Multimedia

CERN Bulletin

2012-01-01

“The LHC has been a huge effort over more than 15 years. It’s not always been easy but today it is performing so spectacularly well that the people who built it should be very proud.” Lyn Evans, head of the LHC project since its beginning and until its commissioning in 2011, shares his recollections with us on the day of the long-awaited discovery.   Lyn Evans, former head of the LHC project, in the LHC tunnel, 2008. While you were building the LHC, were you expecting it to perform so well? Lyn Evans: I knew that the machine had been beautifully designed and was being built extremely well – but I could not have expected that such wonderful results could be achieved in so little time. What are the reasons for such a good performance? Evans: The LHC was designed to really push the limits; I think that the machine has got more than 30 years of accumulated experience in its design. The fact is the LHC has already exceeded the design luminosity at the en...

Topographic Anterograde and Retrograde Memory for Spatial ...

African Journals Online (AJOL)

The present study was on the effects of haloperidol injection on anterograde and retrograde topographic memories for spatial behaviours in Long Evan rats. Twelve Long Evan albino rats weighing 0.5 – 0.8 kg (6 males, 6 females) were used for the study. Complex Maze Box of 14 unit T Alley from the Royal Institute of ...

short history of anti-rheumatic therapy. IV. Corticosteroids

Directory of Open Access Journals (Sweden)

P. Marson

2011-06-01

Full Text Available In 1948 a corticosteroid compound was administered for the first time to a patient affected by rheumatoid arthritis by Philip Showalter Hench, a rheumatologist at the Mayo Clinic in Rochester, Minnesota (USA. He was investigating since 1929 the role of adrenal gland-derived substances in rheumatoid arthritis. For the discovery of cortisone and its applications in anti-rheumatic therapy, Hench, along with Edward Calvin Kendall and Tadeusz Reichstein, won the 1950 Nobel Prize for Medicine. In this review we summarize the main stages that led to the identification of the so-called compound E, which was used by Hench. We also consider the subsequent development of steroid therapy in rheumatic diseases, through the introduction of new molecules with less mineralocorticoid effects, such as prednisone, and more recently, deflazacort.

COMPOSITION OF THE JOINT ADVISORY APPEALS BOARD - 2003 Exercise

CERN Multimedia

2003-01-01

Appointed by the Director-GeneralAppointed by the Staff Association MembersChristian Fabjan/EPIrene Seis/IT 1st deputies Lars Leistam/ESTJean-Claude Carlier/TIS 2nd deputies Luc Durieu/ABMorna Robillard/HR Dr Fabjan and Mrs Seis have drawn up the following list of staff members from among whom the Chairperson of the Board may be chosen when required : Appointed by the Director-GeneralAppointed by the Staff AssociationPhilippe Charpentier/EPCorrado Pettenati/ETT Christophe Delamare/EST Ignacio Reguero/IT Eugenia Hatziangeli/AB Alasdair smith/EP Tadeusz Kurtyka/EST Pierre Strubin/AT Mats Møller/AS Elena Wildner/AT Mediators [see Administrative Circular N° 6 (Rev. 1) entitled "Review procedure"] will also be selected from this list of ten staff members. Human Resources DivisionTel. 74128

Skreślenia - gry tekstowe Tadeusza Różewicza

Directory of Open Access Journals (Sweden)

Stanisław Jaworski

2007-09-01

Full Text Available For nearly thirty years now Tadeusz Różewicz has published his poems with their earlier version (e.g. Płaskorzeźba Bas-relief, (1991. It can be described in terms of genetic criticism, talking of a way to the ultimate version, a way to self-cognition. It is also possible - and this is the task of this essay - to see in it a specific text game, aiming at double conveyance. A new whole is being created, which consists as if of the discarded, deleted elements, but here revoked in a new function - manifestation of the text in its many plots. From the clash of rough first drafts, deletions and "ultimate" versions as if a new poem arises, "the third poem", which exists only on the scene of reading.

Edgewood Biosensors Test Bed Hand-held and Man-Portable Edition

Science.gov (United States)

2013-09-01

CORPORATION, INC. Gunpowder, MD 21010-0068 Evan Skowronski TMG BIOSCIENCES Incline Village, NV 89451 September 2013 Approved for public release...Emanuel, Peter (ECBC); Rivers, Bryan; Schaffer, Eric (SAIC); and Skowronski, Evan ( TMG Biosciences) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...21010-0068 TMG Biosciences, 774 Mays Blvd. #10-455, Incline Village, NV 89451 8. PERFORMING ORGANIZATION REPORT NUMBER ECBC-TR-1201 9

Interservice/Industry Training, Simulation and Education Conference Partnerships for Learning in the New Millennium Abstracts

Science.gov (United States)

2000-01-01

DISTRIBUTED POWER ARCHITECTURE John McCrillis, Kevin Cahill, Joseph Kerkes, Clint Steffan BAE SYSTEMS Flight Simulation and Training A typical full...DATABASE? Serge J. Olszanskyj Evans & Sutherland Computer Corporation We discuss the complexity of making a synthetic environment (i.e., a database...and architectures.This paper describes a DB conversion process jointly developed by Boeing, Westar, Evans and Sutherland (E&S), and Terrain Experts

Wealth, equity and health care: a critique of a "population health" perspective on the determinants of health. Critical Social Science Group.

Science.gov (United States)

Poland, B; Coburn, D; Robertson, A; Eakin, J

1998-04-01

In this paper we examine the recent ascendancy of a "population health" perspective on the "determinants of health" in health policy circles as conceptualized by health economists and social epidemiologists such as Evans and Stoddart [Evans and Stoddart (1990) Producing health, consuming health care. Social Science & Medicine 31(12), 1347 1363]. Their view, that the financing of health care systems may actually be deleterious for the health status of populations by drawing attention away from the (economic) determinants of health, has arguably become the "core" of the discourse of "population health". While applauding the efforts of these and other members of the Canadian Institute for Advanced Research for "pushing the envelope", we nevertheless have misgivings about their conceptualization of both the "problem" and its "solutions", as well as about the implications of their perspective for policy. From our critique, we build an alternative point of view based on a political economy perspective. We point out that Evans and Stoddart's evidence is open to alternative interpretations--and, in fact, that their conclusions regarding the importance of wealth creation do not directly reflect the evidence presented, and are indicative of an oversimplified link between wealth and health. Their view also lacks an explicit substantive theory of society and of social change, and provides convenient cover for those who wish to dismantle the welfare state in the name of deficit reduction. Our alternative to the "provider dominance" theory of Evans and Stoddart and colleagues stresses that the factors or forces producing health status, which Evans and Stoddart describe, are contained within a larger whole (advanced industrial capitalism) which gives the parts their character and shapes their interrelationships. We contend that this alternative view better explains both how we arrived at a situation in which health care systems are as costly or extensive as they are, and suggests

Noniterative Multireference Coupled Cluster Methods on Heterogeneous CPU-GPU Systems

Energy Technology Data Exchange (ETDEWEB)

Bhaskaran-Nair, Kiran; Ma, Wenjing; Krishnamoorthy, Sriram; Villa, Oreste; van Dam, Hubertus JJ; Apra, Edoardo; Kowalski, Karol

2013-04-09

A novel parallel algorithm for non-iterative multireference coupled cluster (MRCC) theories, which merges recently introduced reference-level parallelism (RLP) [K. Bhaskaran-Nair, J.Brabec, E. Aprà, H.J.J. van Dam, J. Pittner, K. Kowalski, J. Chem. Phys. 137, 094112 (2012)] with the possibility of accelerating numerical calculations using graphics processing unit (GPU) is presented. We discuss the performance of this algorithm on the example of the MRCCSD(T) method (iterative singles and doubles and perturbative triples), where the corrections due to triples are added to the diagonal elements of the MRCCSD (iterative singles and doubles) effective Hamiltonian matrix. The performance of the combined RLP/GPU algorithm is illustrated on the example of the Brillouin-Wigner (BW) and Mukherjee (Mk) state-specific MRCCSD(T) formulations.

Shifting Focus: Assessing the Role of U.S. Army Special Forces in the Counterproliferation of Weapons of Mass Destruction

Science.gov (United States)

2014-06-01

would only further enhance this effect. An article in Foreign Policy by Gareth Evans describes cooperative security as the theory that explains the... Gareth Evans, “Cooperative Security and Intrastate Conflict,” Foreign Policy, no. 96 (Autumn 1994): 7. doi: 10.2307/1149213 20 John H. Herz...of the Oversight and Government Reform Committee, Brookings Institution Fellow Vanda Felbab- Brown discussed the effects of supply-side policies on

Technical Evaluation of Sample-Processing, Collection, and Preservation Methods

Science.gov (United States)

2014-07-01

Belcamp, MD 21017-1543 Bryan Rivers Eric Schaffer LEIDOS, INC. Gunpowder, MD 21010-0068 Evan Skrowronski TMG BIOSCIENCES, LLC Incline Village...Bryan; Schaffer, Eric (Leidos); and Skrowronski, Evan ( TMG Biosciences) 5d. PROJECT NUMBER R.0000061.61.41.1 5e. TASK NUMBER 5f. WORK UNIT...Leidos, Inc., P.O. Box 68, Gunpowder, MD 21010-0068 TMG Biosciences LLC, 774 Mays Blvd., Incline Village, NV 89451-9613 8. PERFORMING ORGANIZATION

APOLLO 17 PRELAUNCH ASTRONAUT TRAINING

Science.gov (United States)

1972-01-01

Apollo Command Module Pilot Evans, left, and Mission Commander Cernan, right, discuss their flight plans as each prepares to fly a T-38 jet aircraft at Patrick Air Force Base just south of the Spaceport. Astronauts Cernan and Evans flew the T-38 aircraft today on training flights over the Kennedy Space Center area to practice flying skills in preparation for upcoming launch to the Moon scheduled 12/06/72.

Influence of obstetric complication severity on brain morphology in schizophrenia: an MR study

Energy Technology Data Exchange (ETDEWEB)

Bersani, G.; Quartini, A.; Manuali, G.; Iannitelli, A. [University of Rome, Polo Pontino, Department of Psychiatric Sciences and Psychological Medicine, Rome (Italy); Pucci, D. [University of Rome, Department of Public Health ' ' G. Sanarelli' ' , Rome (Italy); Conforti, F. [University of Rome, I Medical Clinic, Magnetic Resonance Imaging Unit, Rome (Italy); Di Biasi, C.; Gualdi, G.

2009-06-15

The purpose of this study was to determine if a causal relationship exists between obstetric complications (OCs) severity and linear magnetic resonance (MR) measurements of brain atrophy in patients with schizophrenia. Linear measurements of ventricular enlargement (bifrontal span, Evans ratio, and bicaudate ratio) and hippocampal atrophy (interuncal distance) were completed on MR images obtained in 47 patients with schizophrenia. Regression analysis was used to look at association with OCs severity, assessed by the ''Midwife protocol'' of Parnas and colleagues. The relationship between MR measurements and phenomenologic variables such as age at onset, illness duration, and exposure to antipsychotic medications was explored. The relationship between MR measurements, OCs severity, and symptom presentation was also investigated. OCs severity was significantly associated with MR measurements of ventricular enlargement (bifrontal span, Evans ratio). As the severity of OCs increased, bifrontal span and Evans ratio increased. This effect was independent of age at onset, illness duration, or even antipsychotic treatment. Interestingly, bifrontal span, Evans ratio, and OCs severity score all showed a significant positive correlation with hallucinatory symptomatology. Although confirmatory studies are needed, our findings would support the idea that environmental factors, in this case severe OCs, might partly contribute to ventricular abnormalities in schizophrenia. (orig.)

Influence of obstetric complication severity on brain morphology in schizophrenia: an MR study

International Nuclear Information System (INIS)

Bersani, G.; Quartini, A.; Manuali, G.; Iannitelli, A.; Pucci, D.; Conforti, F.; Di Biasi, C.; Gualdi, G.

2009-01-01

The purpose of this study was to determine if a causal relationship exists between obstetric complications (OCs) severity and linear magnetic resonance (MR) measurements of brain atrophy in patients with schizophrenia. Linear measurements of ventricular enlargement (bifrontal span, Evans ratio, and bicaudate ratio) and hippocampal atrophy (interuncal distance) were completed on MR images obtained in 47 patients with schizophrenia. Regression analysis was used to look at association with OCs severity, assessed by the ''Midwife protocol'' of Parnas and colleagues. The relationship between MR measurements and phenomenologic variables such as age at onset, illness duration, and exposure to antipsychotic medications was explored. The relationship between MR measurements, OCs severity, and symptom presentation was also investigated. OCs severity was significantly associated with MR measurements of ventricular enlargement (bifrontal span, Evans ratio). As the severity of OCs increased, bifrontal span and Evans ratio increased. This effect was independent of age at onset, illness duration, or even antipsychotic treatment. Interestingly, bifrontal span, Evans ratio, and OCs severity score all showed a significant positive correlation with hallucinatory symptomatology. Although confirmatory studies are needed, our findings would support the idea that environmental factors, in this case severe OCs, might partly contribute to ventricular abnormalities in schizophrenia. (orig.)

Procedure for obtaining visas for Switzerland and France

CERN Multimedia

Relations with the Host States Service

2011-01-01

SIGNATURE RIGHTS - In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories.  Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil.  Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Patrick FASSNACHT (PH-ADO) David FOSTER (IT – DI) Nathalie GRÜB (PH – AGS) Tjitske KEHRER (DG-DI) Tadeusz KURTYKA (DG – PRJ) Cécile NOELS (DG – PRJ) Maria QUINTAS (HR – SPS) Kate RICHARDSON (PH-AGS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla TIHINEN (PH – A...

Procedure for obtaining visas for Switzerland and France - Signature rights

CERN Multimedia

2013-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories.  Where relevant, detailed procedures for obtaining visas apply.   Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Patrick FASSNACHT (PH-ADO) David FOSTER (IT – DI) Nathalie GRÜB (PH – AGS) Tadeusz KURTYKA (DG – PRJ) Markus NORDBERG (PH – ADO) Cécile NOELS (DG – PRJ) Maria QUINTAS (HR – SPS) Kate RICHARDSON (PH-AGS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla TIHINEN (PH – AGS) Emmanuel...

Procedure for obtaining visas for Switzerland and France - Signature rights

CERN Multimedia

DG Unit

2010-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel onto their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the Note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d’accueil. Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Sylvie DETHURENS FAVEZ (HR – SPS) David FOSTER (IT – DI) Nathalie GRUB (PH – AGS) Tadeusz KURTYKA (DG – PRJ) Jean-Pol MATHEYS (BE – ASR) Cécile NOELS (DG – PRJ) Connie POTTER (PH – AGS) Maria QUINTAS (HR – SPS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla...

Procedure for obtaining visas for Switzerland and France Signature rights

CERN Multimedia

DG Unit

2012-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories.  Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Patrick FASSNACHT (PH-ADO) David FOSTER (IT – DI) Nathalie GRÜB (PH – AGS) Tjitske KEHRER (DG-DI) Tadeusz KURTYKA (DG – PRJ) Markus NORDBERG (PH – ADO) Cécile NOELS (DG – PRJ) Maria QUINTAS (HR – SPS) Kate RICHARDSON (PH-AGS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla TIHINEN (PH – AG...

Confronting the Past

DEFF Research Database (Denmark)

Bondebjerg, Ib

2013-01-01

Historical films are important carriers of collective memory, and as a genre historical films can activate both strong feelings and strong debate. Historical fiction films often tell very accurate and almost documentary stories, but fictional films have the freedom to make historical reality...... in quite another way than factual historical films. This article deals with some of the most important historical film genres and uses a general theory of genres, emotions, memory and history to analyse the historical films of Polish film director Andrzej Wajda, especially those made post 1989. Dealing...... with both his heritage drama Pan Tadeusz (1999) and critical historical drama Katyn (2007), the article analyses the ways in which Wajda uses historical narratives to comment on both history and contemporary society, and how this strategy is reflected in all his historical films. The article argues...

Who's who on the Board

International Nuclear Information System (INIS)

Anon.

1988-01-01

Brief summaries of the curriculum vitae and present positions held by each member of the National Radiological Protection Board are given. The members are Sir Richard Southwood, Mr. A.M. Allen, Professor A. Barret, Professor J.H. Edwards, Professor H.J. Evans, Professor K.J. Evans, Professor P. Haggett, Professor J.R. Lee, Professor J.S. Orr, Dr. R. Owen, Professor J. Peto, Dr. D.H. Roberts and Mr. M.E. Trowbridge. (U.K.)

Do safeguarding concerns deter young people’s access to condoms? Issues about integrating sexual health services online

OpenAIRE

Evans, Andrew B.; Evans, David T.

2016-01-01

Condoms have been distributed freely, and regionally across England, since the ‘Teenage Pregnancy Strategy’ (Social Inclusion Unit, 1999) which highlighted England as having one of the highest rates of unplanned teenage conceptions in Western Europe. With the aim of making more accessible contraception and sex safer resources and protecting against infections, young people can obtain free condoms through selected registration and distribution points (Evans, 2005; Hadley and Evans, 2013). In 2...

Three-Dimensional Computer Graphics Brain-Mapping Project

Science.gov (United States)

1988-03-24

1975-76, one of these brains was hand digitized. It was then reconstructed three dimensionally, using an Evans and Sutherland Picture System 2. This...Yakovlev Collection, we use the Evans and Sutherland Picture System 2 which we have been employing for this purpose for a dozen years. Its virtue is...careful, experimentally designed new protocol (See Figure 20). Most of these heads were imaged with Computed Tomography, thanks to Clint Stiles of Picker

Herbal composition Gambigyeongsinhwan (4) from Curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka Long-Evans Tokushima Fatty rats.

Science.gov (United States)

Roh, Jong Sung; Lee, Hyunghee; Woo, Sangee; Yoon, Miso; Kim, Jeongjun; Park, Sun Dong; Shin, Soon Shik; Yoon, Michung

2015-08-02

Adipocyte lipid accumulation due to impaired fatty acid oxidation causes adipocyte hypertrophy and adipose tissue increment, leading to obesity. The aim of this study was to determine the antiobesity effects of the herbal composition Gambigyeongsinhwan (4) (GGH(4)) composed of Curcuma longa L. (Zingiberaceae), Alnus japonica (Thunb.) Steud. (Betulaceae), and the fermented traditional Korean medicine Massa Medicata Fermentata. The effects of GGH(4) and the individual components on lipid accumulation in 3T3-L1 adipocytes and body weight gain in Otsuka Long-Evans Tokushima Fatty (OLETF) rats were examined using Oil red O staining, hematoxylin and eosin staining, quantitative real-time PCR, and peroxisome proliferator-activated receptor α (PPARα) transactivation assay. GGH(4), individual components, and an active principle of Curcuma longa curcumin inhibited lipid accumulation and mRNA levels of adipocyte-specific genes (PPARγ, aP2, and C/EBPα) in 3T3-L1 adipocytes compared with control cells. Treatment with GGH(4), the individual components or curcmumin increased mRNA levels of mitochondrial (CPT-1, MCAD, and VLCAD) and peroxisomal (ACOX and thiolase) PPARα target genes. GGH(4) and the individual components also increased PPARα reporter gene expression compared with control cells. These effects were most prominent in GGH(4)-treated cells. However, the PPARα antagonist GW6471 reversed the inhibitory effects of GGH(4) on adipogenesis. An in vivo study showed that GGH(4) decreased body weight gain, adipose tissue mass, and visceral adipocyte size with increasing mRNA levels of adipose tissue PPARα target genes in OLETF rats. These results demonstrate that GGH(4) has an antiobesity effects through the inhibition of adipocyte lipid accumulation, and this process may be mediated in part through adipose PPARα activation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Confronting Misinformation in Climate Change Higher Education

Science.gov (United States)

Bedford, D. P.

2012-12-01

Among the many challenges faced by climate change educators is the highly politicized nature of the subject matter (e.g. McCright and Dunlap, 2011) and the associated misinformation from key media outlets and websites (e.g. see Oreskes and Conway, 2010). Students typically do not enter the classroom as 'blank slates', but often have already formed some opinion about climate change which may or may not be based on reputable sources. Further, many students have lives outside the classroom and/or off campus, and even those who do live in an isolated bubble of campus life will eventually graduate. Thus, providing students with a level of climate change knowledge and understanding robust enough to cope with misinformation may be an important goal for educators. This paper presents a case study of the direct use of climate change misinformation as a college-level classroom activity. Some research from other fields (notably psychology) has found that directly addressing misconceptions in the classroom can be the most effective means of dispelling them (Kowalski and Taylor, 2009). However, directly confronting misinformation in the classroom carries inherent risks, such as reinforcing misconceptions (e.g. Cook and Lewandowsky, 2011). This paper therefore considers approaches to minimizing those risks while attempting to maximize the possible benefits. This paper argues that use of misinformation as a teaching tool can provide useful exercises in critical thinking, testing of content knowledge, and consideration of the nature of science. Cook, J. and S. Lewandowsky. 2011. The Debunking Handbook. Online publication available www.skepticalscience.com/docs/Debunking_Handbook.pdf. Accessed 7 July 2012. Kowalski, P. and A.K. Taylor. 2009. DOI: 10.1080/00986280902959986. McCright, A., and R.T. Dunlap. 2011. The politicization of climate change and polarization in the American public's views of global warming, 2001-2010. The Sociological Quarterly 52:2, 155-194. Oreskes, N. and E

Cognitive success: instrumental justifications of normative systems of reasoning

OpenAIRE

Schurz, Gerhard

2014-01-01

In the first part of the paper (sec. 1–4), I argue that Elqayam and Evan's (2011) distinction between normative and instrumental conceptions of cognitive rationality corresponds to deontological vs. teleological accounts in meta-ethics. I suggest that Elqayam and Evans' distinction be replaced by the distinction between a-priori intuition-based vs. a-posteriori success-based accounts of cognitive rationality. The value of cognitive success lies in its instrumental rationality for almost-all p...

Cardiovascular Ultrasound of Neonatal Long Evans Rats ...

Science.gov (United States)

This abstract describes the use of a relatively new technology, cardiovascular ultrasound (echocardiography) for evaluating developmental toxicity affecting heart development. The abstract describes the effects of two known cardiac teratogens, trichloroacetic acid and dimethadione, and their effects as determined by echocardiography. This abstract describes the use and development of a relatively new technology, cardiovascular ultrasound (echocardiography) for evaluating developmental toxicity affecting heart development.

Meie igapäevane paanika / Ott Karulin

Index Scriptorium Estoniae

Karulin, Ott, 1980-

2007-01-01

Kahest Vanemuise teatri lavastusest Tartus - Saksa Kultuuri Instituudis etendunud Ingvar Ambjornseni-Axel Hellsteniuse "Elling" Ain Mäeotsa lavastuses ja Laura Cunninghami "Beautiful Bodies" Vanemuises, lavastaja Jüri Lumiste

Kwashiorkor and Intellectual Development | Evans | South African ...

African Journals Online (AJOL)

Forty Cape Coloured children who had been hospitalized for kwashiorkor in infancy were compared with their siblings on an intelligence test battery at the 10th ... groups found by previous investigators may be accounted for by the independent operation of non-nutritive variables in the social and emotional environment.

OrthoImagery Submission for Evans County, GA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — NAIP imagery is available for distribution within 60 days of the end of a flying season and is intended to provide current information of agricultural conditions in...

Golden Hadron awards for the LHC's top suppliers.

CERN Multimedia

Maximilien Brice

2003-01-01

The following firms have been selected to receive a GOLDEN HADRON AWARD 2003, in recognition of their outstanding achievement: JDL TECHNOLOGIES, Belgium "in producing automatic cable inspection systems", FURUKAWA ELECTRIC COMPANY, Japan "in producing high quality superconducting cable", IHI Corporation, Japan, and LINDE KRYOTECHNIK, Switzerland "in producing novel 1.8 K refrigeration units based on advanced cold compressor technology" for the Large Hadron Collider.Photos 01, 02: Recipients of the 2003 Golden Hadron awards at the presentation ceremony on 16 May.Photo 03: LHC project leader Lyn Evans updates the award recipients on work for CERN's new accelerator.Photo 04: René Joannes of JDL Technologies (left) receives a Golden Hadron award from LHC project leader Lyn Evans.Shinichiro Meguro, managing director of Furukawa Electric Company, receives a Golden Hadron award from LHC project leader Lyn Evans.Photo 06: Kirkor Kurtcuoglu of Linde Kryotechnik (left) and Motoki Yoshinaga, associate director of IHI...

Gold awards for CERN's top suppliers!

CERN Multimedia

2003-01-01

CERN's awards to the LHC project's best suppliers are now into their second year. Three companies received 'Golden Hadrons' for 2003. The Golden Hadron awards were presented to the delighted representatives of the winning firms by LHC Project Leader Lyn Evans on Friday 16 May. Only three out of the LHC's four hundred suppliers were lucky enough to receive a gold award. The consortium IHI (Japan)-Linde Kryotechnik (Switzerland), the Belgian company JDL Technologies and the Japanese firm Furukawa Electric Company were rewarded not only for their technical and financial achievements but also for their compliance with contractual deadlines. The 2003 Golden Hadron winners with Lyn Evans. From left to right: Armin Senn, Thomas Voigt, Kirkor Kurtcuoglu of LINDE KRYOTECHNIK ; Tadaaki Honda, Project Leader and Motoki Yoshinaga, Associate Director of IHI Corporation ; Lyn Evans, LHC Project Leader; Shinichiro Meguro, Managing Director of FURUKAWA ELECTRIC COMPANY ; Nobuyoshi Saji, Consulting Engineer of IHI Corporatio...

Intoduction to the Issue (2011/2

Directory of Open Access Journals (Sweden)

Wojciech HANUSZKIEWICZ

2011-12-01

Full Text Available Seven articles — out of the nine presented here to the Reader — undertake our leading theme: Tracing Liminal and Boundary Experience in Philosophical and Religious Discourse. Three articles from that group (written by Małgorzata Bogaczyk-Vormayr, Piotr Augustyniak and Anna Szyrwińskaexplore various aspects of the boundary experience in a historical perspective. The next four pick up the same theme in a contemporary perspective: the articles of Joachim Piecuch, Tadeusz Gadacz and Antoni Szwed discuss the philosophy of Józef Tischner, the article by Urszula Idziak presents the debate between Jacques Derrida and Paul Ricoeur concerning the boundary experience of death. The remaining two articles published here are not connected with the leading theme — Magdalena Nowak presents a history of the concept of Einfühlung and Jacquette Dale tries to improve the diagram method used in logical argument analysis.

15th Anniversary of the Molecular Techniques Unit at the Department of Forensic Medicine at Wroclaw Medical University.

Science.gov (United States)

Pluta, Dominika; Tokarski, Miron; Karpiewska, Anna; Dobosz, Tadeusz

2017-01-01

Molecular Techniques Unit at the Department of Forensic Medicine, Wroclaw Medical University has been operating since December 2003. Soon it will be 15 years since its establishment. This anniversary become an inspiration to write down the story of this institution whose origins illustrate the immense changes that have taken place in forensic genetics. The aim of our work was also to consolidate the professional achievements of Professor Tadeusz Dobosz, chief of the Unit, one of the pioneers of introducing DNA testing technology into Polish forensic medicine. The most important achievements of the Unit include participation in two EU research projects, the development of a non-destructive method of extraction of genetic material, research in field of gene therapy and certification of the Laboratory of the Molecular Techniques Unit by the Polish Accreditation Center (PCA) confirming compliance with the requirements of the PN-EN ISO/IEC 17025:2005 standard.

Craniofacial form is altered by chronic adult exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD in Han/Wistar and Long–Evans rats with different aryl hydrocarbon receptor (AhR structures

Directory of Open Access Journals (Sweden)

Sabrina B. Sholts

2015-01-01

Full Text Available Mammalian bone has shown a variety of responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD exposure in experimental and wildlife studies. Although many responses have been well characterized in the postcranial skeleton, dioxin-induced effects on the cranium are largely unknown. In this study, we investigated the effects of chronic adult exposure to TCDD on cranial size and shape in dioxin-resistant Han/Wistar (H/W and dioxin-sensitive Long–Evans (L–E rat strains. Three-dimensional landmark configurations for the face, vault, and base of the cranium were recorded and analyzed using geometric morphometrics (GM and dose–response modeling. The strongest effects were shown by L–E and H/W rats with daily exposures of 100 and 1000 ng TCDD/kg bw/day, respectively, resulting in significant reductions in centroid size (CS in all three cranial modules for both strains except for the vault in H/W rats. Consistent with previous evidence of intraspecific variation in TCDD resistance, the benchmark doses (CEDs for cranial size reduction in L–E rats were roughly 10-fold lower than those for H/W rats. For both strains, the face showed the greatest size reduction from the highest doses of TCDD (i.e., 3.6 and 6.3% decreases in H/W and L–E rats, respectively, most likely related to dose-dependent reductions in limb bone size and body weight gain. However, intrinsic morphological differences between strains were also observed: although the control groups of H/W and L–E rats had vaults and bases of comparable size, the face was 6.4% larger in L–E rats. Thus, although H/W rats possess an altered aryl hydrocarbon receptor (AhR that appears to mediate and provides some resistance to TCDD exposure, their smaller reductions in facial size may also relate to strain-specific patterns of cranial development and growth. Future research will be aimed at understanding how ontogenetic factors may modulate toxic effects of prenatal and lactational exposure on

NATO Advanced Research Workshop on Nuclear Magnetic Resonance of Paramagnetic Macromolecules

CERN Document Server

1995-01-01

Since A. Kowalsky's first report of the spectrum of cytochrome c in 1965, interest in the detection, assignment and interpretation of paramagnetic molecules has surged, especially in the last decade. Two classes of systems have played a key role in the development of the field: heme proteins and iron-sulfur proteins. These two systems are unique in many respects, one of which is that they contain well-defined chromophores, each of which can be studied in detail outside the protein matrix. They are the most successfully studied macromolecules, and the first eight and last six of the seventeen contributions to this book deal with heme and/or iron-sulfur proteins. The middle three chapters survey the progress on, and significant promise of, more difficult systems which do not possess a chromophore, but which have nevertheless yielded remarkable insights into their structure.

Microculture for the isolation of Leishmania parasites from cutaneous lesions -- Sri Lankan experience.

Science.gov (United States)

Ihalamulla, R L; Rajapaksa, U S; Karunaweera, N D

2005-09-01

Novy, McNeal and Nicolle (NNN) medium and Evans' modified Tobie's medium are two conventional media for the isolation of Leishmania parasites in in-vitro cultures. Both are biphasic, with a solid layer of blood agar, and are normally prepared in glass test-tubes. In Sri Lanka at least, a monophasic microcapillary culture, based solely on RPMI 1640 medium supplemented with foetal calf serum, has been found simpler, more economical and more sensitive, for the isolation of L. donovani from skin lesions, than the use of Evans' modified Tobie's medium.

Dollar Summary of Prime Contract Awards by State, County, Contractor, and Place, FY83, Part 2 (Oceana, Michigan - Weston, Wyoming).

Science.gov (United States)

1983-01-01

WILSON AIR SYSTEMS INC WILSON 1,302 745 557 NCAR WILSON FIRESTONE TIRE a RUBBER CO WILSON 42 42 NCAR WILSON INDUSTRIAL TECH INC ELM CITY 27 27 NCAR...THERMATICS ELM CITY 807 34 773 NCAR WILSON TOTAL COUNTY 3,840 836 359 1,214 1,431 NCAR YADKIN ASTORIA BRAID MFG CO INC BOONVILLE 113 113 NCAR YADKIN TOTAL...INC SLIPPERY ROCK 152 152 PA BUTLER M S A RESEARCH CORP EVANS CITY 227 227 PA BUTLER MINE SAFETY APPLIANCES CO EVANS CITY 8,531 253 311 1,339 6,628 PA

Basic survey for joint implementation, etc. Basic feasibility study on energy conservation at Tadeusz Sendzimir Steelworks

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

For the purpose of reducing greenhouse effect gas emissions, a feasibility study was conducted on the energy conservation at Huta Sendzimir Steelworks in Poland. The study was made on quantity-energy consuming facilities such as blast furnace, sintering plant and steelmaking plant, power plant, by-producing gas, purchased power, etc. Moreover, as to the energy consuming system, surveys were made on the exhaust heat recovery equipment already introduced and energy saving equipment for pig iron/steel making. As a result, it was found out that Huta Sendzimir Steelworks has an ability and experiences for implementation of the energy conservation project with no problems. As methods to save energy in individual production process, the introduction of the following was proposed: pressure recovery turbine of blast furnace, equipment for high temperature stove exhaust heat recovery, sintering cooler exhaust heat recovery, oxygen combustion furnace exhaust gas recovery, etc. By the introduction of these equipment, the reduction amount of greenhouse effect gas emissions per year will be approximately 180,000 ton-CO2. (NEDO)

Różewicz about himself as someone else

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Ryszard Kazimierz Przybylski

2014-01-01

Full Text Available It seems that Tadeusz Różewicz’s poem titled Francis Bacon or Diego Velazquez in a Dentist’s Chair is dedicated to the works of the author of Studies of Crucifixion. In fact, Różewicz writes about the impression that Bacon’s art left on him when he saw it in galleries and museums. This poem is also about fascination. Contrary to what may seem intuitive, it is not an attempt to describe the poet’s own way of interpreting these works; and even if so, this is only true to a limited extent. For Różewicz, Bacon’s works were just a pretext to look at himself, especially at his own early poems, from a distance – from a somewhat ironic distance. In this way the poet is able to present himself as “the other”, thus referring to the title of Paul Ricoeur’s book.

TEN RILLINGTON PLACE AND THE CHANGING POLITICS OF ABORTION IN MODERN BRITAIN.

Science.gov (United States)

Jones, Emma L; Pemberton, Neil

2014-12-01

This article addresses the social, cultural, and political history of backstreet abortion in post-war Britain, focusing on the murders of Beryl Evans and her daughter Geraldine, at Ten Rillington Place in 1949. It shows how the commonplace connection of John Christie to abortion and Beryl Evan's death was not a given in the wider public, legal, political, and forensic imagination of the time, reflecting the multi-layered and shifting meanings of abortion from the date of the original trials in the late 1940s and 1950s, through the subsequent judicial and literary reinvestigations of the case in the 1960s, to its cinematic interpretation in the 1970s. Exploring the language of abortion used in these different contexts, the article reveals changes in the gendering of abortionists, the increasing power and presence of abortion activists and other social reformers, the changing representation of working-class women and men, and the increasing critique of the practice of backstreet abortion. The case is also made for a kind of societal blind spot on abortion at the time of both the Evans and Christie trials; in particular, a reluctance to come to terms with the concept of the male abortionist, which distorted the criminal investigations and the trials themselves. Only when public acceptance for legalizing abortion grew in the more liberal climate of the 1960s and beyond did a revisionist understanding of the murder of Beryl Evans, in which abortion came to be positioned as a central element, gain a sustained hearing.

Relative locality and the soccer ball problem

International Nuclear Information System (INIS)

Amelino-Camelia, Giovanni; Freidel, Laurent; Smolin, Lee; Kowalski-Glikman, Jerzy

2011-01-01

We consider the behavior of macroscopic bodies within the framework of relative locality [G. Amelino-Camelia, L. Freidel, J. Kowalski-Glikman, and L. Smolin, arXiv:1101.0931]. This is a recent proposal for Planck scale modifications of the relativistic dynamics of particles which are described as arising from deformations in the geometry of momentum space. We consider and resolve a common objection against such proposals, which is that, even if the corrections are small for elementary particles in current experiments, they are huge when applied to composite systems such as soccer balls, planets, and stars, with energies E macro much larger than M P . We show that this soccer ball problem does not arise within the framework of relative locality because the nonlinear effects for the dynamics of a composite system with N elementary particles appear at most of order E macro /N·M P .

Performance of four different rat strains in the autoshaping, two-object discrimination, and swim maze tests of learning and memory.

Science.gov (United States)

Andrews, J S; Jansen, J H; Linders, S; Princen, A; Broekkamp, C L

1995-04-01

The performance of four strains of rats commonly used in behavioural research was assessed in three different tests of learning and memory. The four strains included three outbred lines (Long-Evans, Sprague-Dawley, Wistar) and one inbred strain (S3). Learning and memory were tested using three different paradigms: autoshaping of a lever press, a two-object discrimination test, and performance in a two-island swim maze task. The pigmented strains showed better performance in the autoshaping procedure: the majority of the Long-Evans and the S3 rats acquired the response, and the majority of the Wistar and Sprague-Dawley failed to acquire the response in the set time. The albino strains were slightly better in the swim maze than the pigmented strains. There appeared to be a speed/accuracy trade-off in the strategy used to solve the task. This was also evident following treatment with the cholinergic-depleting agent hemicholinium-3. The performance of the Long-Evans rats was most affected by the treatment in terms of accuracy and the Wistar and Sprague-Dawleys in terms of speed. In the two-object discrimination test only the Long-Evans showed satisfactory performance and were able to discriminate a novel from a known object a short interval after initial exposure. These results show large task- and strain-dependent differences in performance in tests of learning and memory. Some of the performance variation may be due to emotional differences between the strains and may be alleviated by extra training. However, the response to pharmacological manipulation may require more careful evaluation.(ABSTRACT TRUNCATED AT 250 WORDS)

Cachexia in cancer: what is in the definition?

Science.gov (United States)

Vanhoutte, Greetje; van de Wiel, Mick; Wouters, Kristin; Sels, Michaël; Bartolomeeussen, Linda; De Keersmaecker, Sven; Verschueren, Caroline; De Vroey, Veronique; De Wilde, Annemieke; Smits, Elke; Cheung, Kin Jip; De Clerck, Liesbeth; Aerts, Petra; Baert, Didier; Vandoninck, Caroline; Kindt, Sofie; Schelfhaut, Sofie; Vankerkhoven, Marc; Troch, Annelies; Ceulemans, Lore; Vandenbergh, Hanne; Leys, Sven; Rondou, Tim; Dewitte, Elke; Maes, Kristel; Pauwels, Patrick; De Winter, Benedicte; Van Gaal, Luc; Ysebaert, Dirk; Peeters, Marc

2016-01-01

This study aimed to provide evidence-based results on differences in overall survival (OS) rate to guide the diagnosis of cancer cachexia. Data collection and clinical assessment was performed every 3 months (5 visits): baseline data, muscle strength, nutritional and psychosocial status. 2 definitions on cachexia using different diagnostic criteria were applied for the same patient population. Fearon et al 's definition is based on weight loss, body mass index (BMI) and sarcopenia. Evans et al nuances the contribution of sarcopenia and attaches additional attention to abnormal biochemistry parameters, fatigue and anorexia. The mean OS rates were compared between patients with and without cachexia for both definitions. Based on the population of 167 patients who enrolled, 70% developed cachexia according to Fearon et al 's definition and 40% according to Evans et al 's definition. The OS in the cachectic population is 0.97 and 0.55 years, respectively. The difference in OS between patients with and without cachexia is more significant using the diagnostic criteria of Evans et al . The focus of Fearon et al on weight loss and sarcopenia over-rates the assignment of patients to the cachectic group and OS rates have less prognostic value. This study presents a correlation with prognosis in favour of Evans et al ' definition as a tool for cachexia diagnosis. This means that weight loss and BMI decline are both key factors in patients with cancer leading to cachexia but less decisive as stated by Fearon et al . Instead, extra factors gain importance in order to predict survival, such as chronic inflammation, anaemia, protein depletion, reduced food intake, fatigue, decreased muscle strength and lean tissue depletion. B300201112334.

Additive effects of cilnidipine, an L-/N-type calcium channel blocker, and an angiotensin II receptor blocker on reducing cardiorenal damage in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes mellitus

Directory of Open Access Journals (Sweden)

Mori Y

2014-06-01

Full Text Available Yutaka Mori,1,2 Shizuka Aritomi,3 Kazumi Niinuma,3 Tarou Nakamura,3 Kenichi Matsuura,1 Junichi Yokoyama,1 Kazunori Utsunomiya1 1Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, Minato-ku, Japan; 2Department of Clinical Research, National Hospital Organization, Utsunomiya National Hospital, Utsunomiya, Japan; 3Research Center, Ajinomoto Pharmaceuticals Co, Ltd, Kanagawa, Japan Abstract: Cilnidipine (Cil, which is an L-/N-type calcium channel blocker (CCB, has been known to provide renal protection by decreasing the activity of the sympathetic nervous system (SNS and the renin–angiotensin system. In this study, we compared the effects of the combination of Cil and amlodipine (Aml, which is an L-type CCB, with an angiotensin (Ang II receptor blocker on diabetic cardiorenal damage in spontaneously type 2 diabetic rats. Seventeen-week-old Otsuka Long-Evans Tokushima Fatty rats were randomly assigned to receive Cil, Aml, valsartan (Val, Cil + Val, Aml + Val, or a vehicle (eight rats per group for 22 weeks. Antihypertensive potencies were nearly equal among the CCB monotherapy groups and the combination therapy groups. The lowering of blood pressure by either treatment did not significantly affect the glycemic variables. However, exacerbations of renal and heart failure were significantly suppressed in rats administered Cil or Val, and additional suppression was observed in those administered Cil + Val. Although Val increased the renin–Ang system, Aml + Val treatment resulted in additional increases in these parameters, while Cil + Val did not show such effects. Furthermore, Cil increased the ratio of Ang-(1–7 to Ang-I, despite the fact that Val and Aml + Val decreased the Ang-(1–7 levels. These actions of Cil + Val might be due to their synergistic inhibitory effect on the activity of the SNS, and on aldosterone secretion through N-type calcium channel antagonism and Ang II

New models of experimental parotitis and parotid gland distension in rats.

Science.gov (United States)

Okada-Ogawa, Akiko; Shinoda, Masamichi; Honda, Kuniya; Iwata, Koichi

2012-01-01

A significant reduction of the escape threshold to mechanical stimulation of the lateral facial skin was observed bilaterally at days 2 and 3 after unilateral complete Freund's adjuvant (CFA) administration into parotid gland. A slight reduction of mechanical escape threshold was also observed in rats with saline administration. The parotid gland inflammation was verified and quantified by measuring the tissue Evans' blue dye extravasation. The Evans' blue concentration in the parotid gland tissues was significantly greater in the CFA-injected rats than that of the saline-injected rats at 72 h after treatment. On day 10 after CFA administration into the parotid gland, the Evans' blue concentration was recovered to the control level. The administration of capsaicin into the parotid gland did not alter neuronal activities in the transition zone between the trigeminal spinal subnucleus interpolaris and caudalis (Vi/Vc). In contrast, capsaicin administration induced significant increases in the receptive field size and mechanical and cold responses of neurons located in superficial laminae of the C1/C2. The subgroup of C1/C2 neurons responded to mechanical distension of the parotid gland, whereas no Vi/Vc neurons responded to parotid distension.

Pyrrhopyginae: gêneros novos e revalidados (Lepidoptera, Hesperiidae Pyrrhopyginae: new and revalidated genera (Lepidoptera, Hespe-riidae

Directory of Open Access Journals (Sweden)

Olaf H.H. Mielke

2002-03-01

Full Text Available The following new genera with their type-species are described: Oxynetrini: Cyclopyge gen. n. - type-species: Pyrrhopyge roscius Hopffer, 1874; Pyrrhopygini: Arnysoria gen. n. - type species: Pyrrhopyga [sic] galgala Hewitson, 1866, Chalypyge gen. n. - type species: Pyrrhopyga [sic] chalybea Scudder, 1872, Creonpyge gen. n. - type species: Pyrrhopyga [sic] creon H. Druce, 1874, Cyanopyge gen. n. - type species: Pyrrhopyge sangaris Skinner, 1921, Gunayan gen. n. - type species: Pyrrhopyga [sic] rhacia Hewitson, 1875, Jonaspyge gen. n. - type species: Pyrrhopyga [sic] Jonas C. Felder & R. Felder, 1859, Melanopyge gen. n. - type species: Pyrrhopyga [sic] maculosa Hewitson, 1866, Mimardaris gen. n. - type species: Pyrrhopyga [sic] sela Hewitson, 1866, Mysarbia gen. n. - type species: Pyrrhopyge sejanus Hopffer, 1874, Ochropyge gen. n. - type species: Pyrrhopyge ruficauda Hayward, 1932. Apyrrothrix Lindsey, 1921 and Yanguna Watson, 1893 are revalidated. The following are revalidated combinations: Apyrrothrix araxes (Hewitson, 1867, Apyrrothrix arizonae (Godman & Salvin, 1893, Yanguna cometes cometes (Cramer, 1770, Yanguna cometes cometides Mabille & Boullet, 1908, Yanguna cometes staudingeri (Plštz, 1879, Yanguna cosyra (H. Druce, 1875, Yanguna spatlosa spatlosa (Hewitson, 1871, Yanguna spatlosa aspllos Mabille & Boullet, 1908, Yanguna spatlosa mabillei H.H. Druce, 1909, Yanguna tetricus Bell, 1931, Yanguna thelersa (Hewitson, 1866, The following are new combinations: Cyclopyge roscius roscius (Hopffer, 1874, Cyclopyge roscius flavomaculata (Bell, 1937, Cyclopyge roscius iphimedia (Plštz, 1886, Yanguna erebus (Plštz, 1879, Gunayan rhacia (Hewitson, 1875, Gunayan rubrlcollts (Sepp, [1841], Gunayan timaeus (Bell, 1931, Chalypyge chalybea chalybea (Scudder, 1872, Chalypyge chalybea chlorts (Evans, 1951, Chalypyge zereda zereda (Hewitson, 1866, Chalypyge zereda hygieia (C. Felder & R. Felder, 1867, Chalypyge zereda insana (Staudinger, 1876, Chalypyge

Características físicas dos minérios de caulim das minas floresta, Cavalheiro, Turvo e Kowalski, em Campo Alegre (SC, e de Trigolândia (PR Physical characteristics of kaolin ores from Floresta, Cavalheiro, Turvo and Kowalski Mines (SC and from Trigolândia Mine (PR

Directory of Open Access Journals (Sweden)

J. C. Biondiv

2000-06-01

Full Text Available A OXFORD fez, em seus minérios, 244 determinações de resistência a flexão, 1601 determinações da retração do minério a 110 ºC, 1508 determinações da retração após queima a 1220 ºC, 877 determinações de perda ao fogo, 1544 de absorção de água, 2288 determinações da dilatação linear a após secagem a 110 ºC e 1128 da dilatação linear após queima a 1220 ºC. Os valores médios, máximos, mínimos e as distribuições dos resultados dessas análises estão mostrados em tabelas e gráficos. Essas determinações e as observações de campo mostram que os depósitos estudados são de dois tipos, denominados Modelo Trigolândia, derivado de pegmatitos, e Modelo Floresta, derivado de rochas vulcânicas ácidas. Com exceção do minério da Mina do Turvo, as médias dos valores das propriedades físicas analisadas estão sempre dentro do intervalo de valores suportado pelo processo industrial da OXFORD. O minério verde, quase todo da Mina Turvo, e o minério marron são os que têm propriedades mais discordantes dos padrões desejados. Nas correlações entre os valores médios das propriedades físicas analisadas foi constatado que as correlações ruins são sempre devidas ao minério de Trigolândia. Considerando todos os valores analisados e não mais as suas médias, nota-se que, com exceção da correlação entre a % de retração após secagem a 110 ºC e a % de retração total, com r = 0,78, todos os outros coeficientes de correlação são muito baixos, menores que 0,60.OXFORD has made 244 determinations of modulus of rupture, 1601 determinations of dry contraction 110 ºC, 1508 determinations of fired contraction 1220 ºC, 877 determinations of ignition loss, 1544 determinations of apparent porosity, 2288 determinations of dry linear dilation (dried at 110 ºC and 1128 determinations of fired linear dilation (fired at 1220 ºC on their kaolin ores. The averages, maximum, minimum and the statistical distribution of these values are shown on tables and graphics. Those determinations and field observations allow to the conclusion that kaolin deposits are of two different types, named Trigolândia model, originated from pegmatites, and Floresta model, derived from acid volcanic rocks. With the exception of the ore from Turvo Mine, the average values of the analyzed physical properties are always into the intervals accepted by Oxford industrial processes, that runs to produce tableware. From Turvo Mine, the green and the brown ores have the more discordant characteristics. For the other ores, from Turvo and the other mines, the average values of their physical characteristics almost always equal the central values of intervals that characterize good ores. If correlations between average values of different physical properties of ores are made, only Trigolândia shows some bad correlations. Taking into account all the analyzed values, and no more the averages, all the correlations are bad. The exception is the correlation between dry retraction and fired retraction, with r = 0,78. All other correlation coefficients are lower than 0,60.

Parallel implementation of multireference coupled-cluster theories based on the reference-level parallelism

Energy Technology Data Exchange (ETDEWEB)

Brabec, Jiri; Pittner, Jiri; van Dam, Hubertus JJ; Apra, Edoardo; Kowalski, Karol

2012-02-01

A novel algorithm for implementing general type of multireference coupled-cluster (MRCC) theory based on the Jeziorski-Monkhorst exponential Ansatz [B. Jeziorski, H.J. Monkhorst, Phys. Rev. A 24, 1668 (1981)] is introduced. The proposed algorithm utilizes processor groups to calculate the equations for the MRCC amplitudes. In the basic formulation each processor group constructs the equations related to a specific subset of references. By flexible choice of processor groups and subset of reference-specific sufficiency conditions designated to a given group one can assure optimum utilization of available computing resources. The performance of this algorithm is illustrated on the examples of the Brillouin-Wigner and Mukherjee MRCC methods with singles and doubles (BW-MRCCSD and Mk-MRCCSD). A significant improvement in scalability and in reduction of time to solution is reported with respect to recently reported parallel implementation of the BW-MRCCSD formalism [J.Brabec, H.J.J. van Dam, K. Kowalski, J. Pittner, Chem. Phys. Lett. 514, 347 (2011)].

Sailing the "Seven C's" of Leadership.

Science.gov (United States)

Weismuller, Penny C; Willgerodt, Mayumi A; McClanahan, Rachel; Helm-Remund, Terri

2016-01-01

Nurses are increasingly being called upon to lead changes within health care. How do nurses and, in particular, school nurses become leaders? School nurses lead daily in their work but often do not recognize themselves as leaders. The "Five C's of Leadership"-character, commitment, connectedness, compassion, and confidence-identified by Kowalski and Yoder-Wise are foundational to the development of leadership and are particularly relevant to school nurses and their role. Two additional attributes found in the literature-courage and capacity-also undergird school nursing practice. In this article, we describe how school nurses already embody these leadership qualities. Each leadership attribute is reviewed in light of the literature, followed by specific examples to demonstrate how school nurses provide leadership. Through these illustrations, school nurses can recognize and embrace their present leadership abilities. In addition, by using the "Seven C's" of leadership, school nurses can enhance their inherent leadership abilities. © 2015 The Author(s).

Calculating earth dam seepage using HYDRUS software applications

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Jakub Nieć

2017-06-01

Full Text Available This paper presents simulations of water seepage within and under the embankment dam of Lake Kowalskie reservoir. The aim of the study was to compare seepage calculation results obtained using analytical and numerical methods. In April 1985, after the first filling of the reservoir to normal storage levels, water leaks was observed at the base of the escarpment, on the air side of the dam. In order to control seepage flow, drainage was performed and additional piezometers installed. To explain the causes of increased pressure in the aquifer under the dam in May 1985 a simplified calculation of filtration was performed. Now, on the basis of archived data from the Department of Hydraulic and Sanitary Engineering using 3D HYDRUS STANDARD software, the conditions of seepage under the dam have been recreated and re-calculated. Piezometric pressure was investigated in three variants of drainage, including drainage before and after modernization.

A NEAR-INFRARED SPECTROSCOPIC SURVEY OF COOL WHITE DWARFS IN THE SLOAN DIGITAL SKY SURVEY

International Nuclear Information System (INIS)

Kilic, Mukremin; Kowalski, Piotr M.; Von Hippel, Ted

2009-01-01

We present near-infrared photometric observations of 15 and spectroscopic observations of 38 cool white dwarfs (WDs). This is the largest near-infrared spectroscopic survey of cool WDs to date. Combining the Sloan Digital Sky Survey photometry and our near-infrared data, we perform a detailed model atmosphere analysis. The spectral energy distributions of our objects are explained fairly well by model atmospheres with temperatures ranging from 6300 K down to 4200 K. Two WDs show significant absorption in the infrared, and are best explained with mixed H/He atmosphere models. Based on the up-to-date model atmosphere calculations by Kowalski and Saumon, we find that the majority of the stars in our sample have hydrogen-rich atmospheres. We do not find any pure helium atmosphere WDs below 5000 K, and we find a trend of increasing hydrogen to helium ratio with decreasing temperature. These findings present an important challenge to understanding the spectral evolution of WDs.

77 FR 10472 - Dow AgroScience LLC; Availability of Petition, Plant Pest Risk Assessment, and Environmental...

Science.gov (United States)

2012-02-22

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority.... Evan Chestnut, Policy Analyst, Biotechnology Regulatory Services, APHIS, 4700 River Road Unit 147...

Experimental acute thrombotic stroke in baboons

International Nuclear Information System (INIS)

Del Zoppo, G.J.; Copeland, B.R.; Harker, L.A.; Waltz, T.A.; Zyroff, J.; Hanson, S.R.; Battenberg, E.

1986-01-01

To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the lenticulostriate arteries (LSA). Inflation of the balloon for 3 hours in six animals produced a stereotypic sustained stroke syndrome characterized by contralateral hemiparesis. An infarction volume of 3.2 +/- 1.5 cm3 in the ipsilateral corpus striatum was documented by computerized tomographic (CT) scanning at 10 days following stroke induction and 3.9 +/- 1.9 cm3 (n = 4) at 14 days by morphometric neuropathologic determinations of brain specimens fixed in situ by pressure-perfusion with 10% buffered formalin. Immediate pressure-perfusion fixation following deflation of the balloon was performed in 16 additional animals given Evans blue dye intravenously prior to the 3 hour MCA balloon occlusion. Light microscopy and transmission electron microscopy consistently confirmed the presence of thrombotic material occluding microcirculatory branches of the right LSA in the region of Evans blue stain, but not those of the contralateral corpus striatum. When autologous 111In-platelets were infused intravenously in four animals from the above group prior to the transient 3 hour occlusion of the right MCA, gamma scintillation camera imaging of each perfused-fixed whole brain demonstrated the presence of a single residual focus of 111In-platelet activity involving only the Evans blue-stained right corpus striatum. Focal right hemispheric activity was equivalent to 0.55 +/- 0.49 ml of whole blood, and the occlusion score derived from histologic examination of the microcirculation of the Evans blue-stained corpus striatum averaged 34.8 +/- 2.8

Sexual dimorphism in hybrids rats.

Science.gov (United States)

Garcia-Falgueras, Alicia; Pinos, Helena; Fernández, Rosa; Collado, Paloma; Pasaro, Eduardo; Segovia, Santiago; Guillamon, Antonio

2006-12-06

Laboratory rat strains descend from Wistar rats as a consequence of artificial selection. Previously we reported that the medial posterior division of the bed nucleus of the stria terminalis (BSTMP) was sexually dimorphic in Wistar and Long-Evans strains while the medial anterior division (BSTMA) and the locus coeruleus (LC) only showed sex differences in the ancestor Wistar strain. The lateral posterior division (BSTLP) was isomorphic in both strains. The present work studies the number of neurons in the BSTMP, BSTMA, BSTLP and LC of male and female Wistar and Long-Evans rats (F(0)) and their hybrid F(1) and F(2) generations. The BSTMP is sexually dimorphic in the F(0), F(1) and F(2) generations while sex differences in the LC are only seen in F(0) Wistar rats but not in the F(0) Long-Evans or the F(1) and F(2) hybrid generations. Sex differences in the BSTMA are seen in F(0) Wistar but not in F(0) Long-Evans rats and completely disappear in the F(2) generations. The number of neurons in the LC of both males and females decreased in heterozygotic individuals (F(1)) but increased in homozygotic (F(2)). However, the number of neurons in the BSTMP changes significantly over the generations, although the ratio of neurons (female/male) is stable and unaffected in homo- or heterozygosis. Thus, the mechanism that regulates the neuronal female/male ratio would be different from the one that controls the number of neurons. The facts that sex differences in the BSTMP are not affected by homo- or heterozygosis and that they are seen in several mammalian orders suggest the existence of a "fixed" type of brain sex differences in the Mammalia Class.

Cognitive Success: Instrumental Justifications of Normative Systems of Reasoning

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Gerhard eSchurz

2014-07-01

Full Text Available In the first part of the paper (sec. 1-4, I argue that Elqayam and Evan's (2011 distinction between normative and instrumental conceptions of cognitive rationality corresponds to deontological versus teleological accounts in meta-ethics. I suggest that Elqayam and Evans' distinction be replaced by the distinction between a-priori intuition-based versus a-posteriori success-based accounts of cognitive rationality. The value of cognitive success lies in its instrumental rationality for almost-all practical purposes. In the second part (sec. 5-7, I point out that the Elqayam and Evans's distinction between normative and instrumental rationality is coupled with a second distinction: between logically general versus locally adaptive accounts of rationality. I argue that these are two independent distinctions should be treated as independent dimensions. I also demonstrate that logically general systems of reasoning can be instrumentally justified. However, such systems can only be cognitively successful if they are paired with successful inductive reasoning, which is the area where the program of adaptive (ecological rationality emerged, because there are no generally optimal inductive reasoning methods. I argue that the practical necessity of reasoning under changing environments constitutes a dilemma for ecological rationality, which I attempt to solve a dual account of rationality.

Cognitive success: instrumental justifications of normative systems of reasoning

Science.gov (United States)

Schurz, Gerhard

2014-01-01

In the first part of the paper (sec. 1–4), I argue that Elqayam and Evan's (2011) distinction between normative and instrumental conceptions of cognitive rationality corresponds to deontological vs. teleological accounts in meta-ethics. I suggest that Elqayam and Evans' distinction be replaced by the distinction between a-priori intuition-based vs. a-posteriori success-based accounts of cognitive rationality. The value of cognitive success lies in its instrumental rationality for almost-all practical purposes. In the second part (sec. 5–7), I point out that the Elqayam and Evans's distinction between normative and instrumental rationality is coupled with a second distinction: between logically general vs. locally adaptive accounts of rationality. I argue that these are two independent distinctions that should be treated as independent dimensions. I also demonstrate that logically general systems of reasoning can be instrumentally justified. However, such systems can only be cognitively successful if they are paired with successful inductive reasoning, which is the area where the program of adaptive (ecological) rationality emerged, because there are no generally optimal inductive reasoning methods. I argue that the practical necessity of reasoning under changing environments constitutes a dilemma for ecological rationality, which I attempt to solve within a dual account of rationality. PMID:25071624

Cognitive success: instrumental justifications of normative systems of reasoning.

Science.gov (United States)

Schurz, Gerhard

2014-01-01

In the first part of the paper (sec. 1-4), I argue that Elqayam and Evan's (2011) distinction between normative and instrumental conceptions of cognitive rationality corresponds to deontological vs. teleological accounts in meta-ethics. I suggest that Elqayam and Evans' distinction be replaced by the distinction between a-priori intuition-based vs. a-posteriori success-based accounts of cognitive rationality. The value of cognitive success lies in its instrumental rationality for almost-all practical purposes. In the second part (sec. 5-7), I point out that the Elqayam and Evans's distinction between normative and instrumental rationality is coupled with a second distinction: between logically general vs. locally adaptive accounts of rationality. I argue that these are two independent distinctions that should be treated as independent dimensions. I also demonstrate that logically general systems of reasoning can be instrumentally justified. However, such systems can only be cognitively successful if they are paired with successful inductive reasoning, which is the area where the program of adaptive (ecological) rationality emerged, because there are no generally optimal inductive reasoning methods. I argue that the practical necessity of reasoning under changing environments constitutes a dilemma for ecological rationality, which I attempt to solve within a dual account of rationality.

Kallikrein-like amidase activity in renal ischemia and reperfusion

Directory of Open Access Journals (Sweden)

M.D. Carattino

2000-05-01

Full Text Available We assessed a kallikrein-like amidase activity probably related to the kallikrein-kinin system, as well as the participation of leukocyte infiltration in renal ischemia and reperfusion. Male C57BL/KSJmdb mice were subjected to 20 or 60 min of ischemia and to different periods of reperfusion. A control group consisted of sham-operated mice, under similar conditions, except for ischemia induction. Kallikrein-like amidase activity, Evans blue extravasation and myeloperoxidase activity were measured in kidney homogenates, previously perfused with 0.9% NaCl. Plasma creatinine concentration increased only in the 60-min ischemic group. After 20 min of ischemia and 1 or 24 h of reperfusion, no change in kallikrein-like amidase activity or Evans blue extravasation was observed. In the mice subjected to 20 min of ischemia, edema was evident at 1 h of reperfusion, but kidney water content returned to basal levels after 24 h of reperfusion. In the 60-min ischemic group, kallikrein-like amidase activity and Evans blue extravasation showed a similar significant increase along reperfusion time. Kallikrein-like amidase activity increased from 4 nmol PNA mg protein-1 min-1 in the basal condition to 15 nmol PNA mg protein-1 min-1 at 10 h of reperfusion. For dye extravasation the concentration measured was near 200 µg of Evans blue/g dry tissue in the basal condition and 1750 µg of Evans blue/g dry tissue at 10 h of reperfusion. No variation could be detected in the control group. A significant increase from 5 to 40 units of DAbs 655 nm g wet tissue-1 min-1 in the activity of the enzyme myeloperoxidase was observed in the 60-min ischemic group, when it was evaluated after 24 h of reperfusion. Histological analysis of the kidneys showed migration of polymorphonuclear leukocytes from the vascular bed to the interstitial tissue in the 60-min ischemic group after 24 h of reperfusion. We conclude that the duration of ischemia is critical for the development of damage

Nutrient enrichment of pineapple waste using Aspergillus niger and ...

African Journals Online (AJOL)

Nutrient enrichment of pineapple waste using Aspergillus niger and Trichoderma viride by solid state fermentation. Evans Otieno Omwango, Eliud Nyaga Mwaniki Njagi, George Owino Orinda, Ruth Nduta Wanjau ...

Pop / Mihkel Raud

Index Scriptorium Estoniae

Raud, Mihkel, 1969-

2003-01-01

Heliplaatidest: Hootie & the Blowfish "Hootie & the Blowfish", Bill Frisell "The Intercontinentals", Evan Dando "Baby I'm Bored", Terre Thaemlitz "Lovebomb", The Mighty Bop feat. Duncan Roy "The Mighty Bop"

Reversible uranyl fluoride nephrotoxicity in the Long Evans rat

International Nuclear Information System (INIS)

Diamond, G.L.; Morrow, P.E.; Panner, B.J.; Gelein, R.M.; Baggs, R.B.

1989-01-01

Severity and duration of renal injury produced by low levels of uranyl fluoride (UO2F2) were examined in the rat. Rats received multiple ip injections of UO2F2 (cumulative dose: 0.66 or 1.32 mg U/kg body wt). Renal injury was characterized histologically by cellular and tubular necrosis of pars recta of proximal tubule (S2 and S3), with less severe cellular injury to thick ascending limb of loop of Henle and collecting tubule. Injury was evident when renal uranium levels were between 0.7 and 1.4 micrograms U/g wet kidney and was most severe when renal uranium burden was between 3.4 and 5.6 micrograms U/g. Repair of injury was rapid, with complete restoration within 35 days after exposure. Associated with injury were abnormalities in renal function, including impaired tubular reabsorption, proteinuria, and enzymuria, which appeared temporally related, to variable degrees, to progression of renal injury. Thus, reversible renal injury occurs in the rat at levels of uranium in kidney below the present Nuclear Regulatory Commission standard of 3 micrograms U/g kidney for renal injury in humans

Dualistlikud juhid : edukas toimetulek paradoksidega / Paul A. L Evans

Index Scriptorium Estoniae

Evans, Paul A. L

2001-01-01

INSEAD'i juhtimisprofessor väidab, et juhtidele esitatud väljakutse seisneb vastandite vahel manööverdamises. Juhtimise 11 paradoksi. Artikkel tõlgitud raamatust "Management 21C: Someday we'll all manage this way", 2000

77 FR 18865 - Workforce Investment Act of 1998 (WIA); Lower Living Standard Income Level (LLSIL)

Science.gov (United States)

2012-03-28

... FEDERAL YOUTH EMPLOYMENT PROGRAMS: Please contact Evan Rosenberg, Department of Labor, Employment and...-3593; Fax: 202- 693-3110 (these are not toll-free numbers); Email: Rosenberg[email protected] . Individuals...

Phytochemicals and nutritional characteristics of ethanol extract of ...

African Journals Online (AJOL)

Ricinodendron Heudelotii) plant were analysed, using standard procedures described by Harbone, 1973, Sofowora, 1993; Trease and Evans, 1989 and Association of Official Analytical Chemist (AOAC) Official method, 1990; 1984 respectively.

Majandamise paradigma vahetus ja Eesti majanduspoliitika / Raivo Rajamäe

Index Scriptorium Estoniae

Rajamäe, Raivo

2005-01-01

Autori hinnangul majanduspoliitilised vastuolud praeguses valitsuskoalitsioonis seoses riikliku riskikapitali fondi strateegia paikapanemisega näitavad ilmekalt, et Eesti riigil puudub tänapäevane nägemus Eesti konkurentsieelistest

Valitsus ja 400 riigiametnikku kolivad Narva / Erik Gamzejev

Index Scriptorium Estoniae

Gamzejev, Erik, 1967-

2007-01-01

Narvas toimub kahepäevane riigiametnike foorum, kus arutatakse koos kutsutud teadlaste ja välisekspertidega riigijuhtimise päevakajalisi probleeme. Ilmunud ka: Severnoje Poberezhje, 2. okt. 2007, lk. 1

76 FR 72724 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Science.gov (United States)

2011-11-25

... activities in Antarctica and designation of certain animals and certain geographic areas a requiring special... this apex predator that might be indicative of ecosystem change. Location Cape Evans (ASPA 155...

Quantitation of passive cutaneous anaphylaxis (PCA) by using radiolabelled antigen

International Nuclear Information System (INIS)

Ring, J.; Seifert, J.; Brendel, W.

1978-01-01

The major problem of detecting reaginic antibody by passive cutaneous anaphylaxis (PCA) is the quantitation of the dye reaction. Radiolabelled antigen was used in an attempt to quantitate the PCA reaction (Radio-PCA). Antisera containing reaginic antibody against human serum albumin (HSA) were produced in rabbits. These antisera were injected into normal rabbit skin in different dilutions. Twentyfour hours later HSA was injected intravenously either with Evans Blue or as 125-I-HSA. Radioactivity found in antibody-containing skin was significantly higher than in control specimens containing saline or normal rabbit serum, as low as antiserum dilutions of 1:1,000. Compared with Evans Blue technique Radio-PCA was able to distinguish quantitatively between different antiserum dilutions at a higher level of statistical significance. (author)

Recognition in Britain for CERN personalities

CERN Multimedia

2001-01-01

Sir Chris Llewellyn Smith Lyn Evans British CERN personalities were rewarded for their contribution to physics in this year's prestigious New Year Honours. Chris Llewellyn Smith, Director General from 1994 to 1998, was knighted for services to particle physics. 'The citation, 'for services to particle physics', obviously includes my period at CERN. The honour therefore recognises the work of everyone at CERN, including particularly the contributions of those who worked with me in the Directorate and the Management Board', said Sir Chris. Lyn Evans, Director of the LHC project, was awarded the CBE, Commander of the British Empire, for services to accelerator physics. Erwin Gabathuler, Director of Research from 1981 to 1983 was awarded the OBE, Officer of the British Empire, for services to physics.

The Economic Outlook and the Role of Credit Intermediation

OpenAIRE

Evans, Charles L.

2008-01-01

Remarks by Charles L. Evans, President and Chief Executive Officer,Federal Reserve Bank of Chicago Chartered Financial Analysts Society of Chicago Lunch Mid-America Club 200 East Randolph Street Chicago, Illinois

Strateegia ja suurte plaanide lõpp / John Kay

Index Scriptorium Estoniae

Kay, John

2001-01-01

Äristrateegia ettevõttes - selle tekkimine, sisu, ülesanded. Tänapäevane ressursipõhine vaade strateegiale, mis põhineb majandustrendi, konkurentsieelise ja eristavate ning jäljendatavate võimete kontseptsioonidel

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2005-01-01

Uutest heliplaatidest Kelly Osbourne "Sleeping in the Nothing", The Black Eyed Peas "Monkey Business", Faith Evans "The First Lady", Joni Mitchell "Songs of a Prairie Girl", Mylene Farmer "Que L'ombre"

78 FR 53482 - Entergy Operations, Inc., River Bend Station, Unit 1; Exemption

Science.gov (United States)

2013-08-29

... effect on the quality of the human environment (78 FR 50454; August 19, 2013). This exemption is... Regulatory Commission. Michele G. Evans, Director, Division of Operating Reactor Licensing, Office of Nuclear...

78 FR 58992 - Notice of Request for Extension of Approval of an Information Collection; Citrus Canker...

Science.gov (United States)

2013-09-25

... quarantined areas, contact Ms. Lynn Evans-Goldner, National Policy Manager, PHP, PPQ, APHIS, 4700 River Road..., including the validity of the methodology and assumptions used; (3) Enhance the quality, utility, and...

77 FR 135 - Exelon Generation Company, LLC, Oyster Creek Nuclear Generating Station; Exemption

Science.gov (United States)

2012-01-03

... not have a significant effect on the quality of the human environment (76 FR 79227, December 21, 2011.... For The Nuclear Regulatory Commission. Michele G. Evans, Director, Division of Operating Reactor...

76 FR 40872 - Request for Extension of Approval of an Information Collection; Domestic Quarantine Notices

Science.gov (United States)

2011-07-12

... diseases, contact Ms. Lynn Evans-Goldner, National Program Manager, Emergency and Domestic Programs, PPQ... quality, utility, and clarity of the information to be collected; and (4) Minimize the burden of the...

78 FR 38450 - Agency Information Collection Activities; Information Collection Renewal; Reverse Mortgage...

Science.gov (United States)

2013-06-26

...: Michael R. Evans, Fair Lending Specialist, Compliance Policy Section, Division of Supervision and Consumer... methodology and assumptions used; (c) Ways to enhance the quality, utility, and clarity of the information to...

72 - 80_Aminu_HPLC1

African Journals Online (AJOL)

pc

HPLC, Gymnema sylvestre, carbohydrate hydrolyzing enzymes, lipid a chronic .... Method. Test for Tannins and Flavonoids was by. Trease and Evans (2002). Soluble Starch ... Fenton reaction was quantified using 2- deoxyribose oxidative ...

77 FR 55509 - Indiana Michigan Power Company; Donald C. Cook Nuclear Plant, Unit 2; Exemption

Science.gov (United States)

2012-09-10

... significant effect on the quality of the human environment and has published an environmental assessment for... Rockville, Maryland, this 23rd day of August, 2012. For the Nuclear Regulatory Commission. Michele Evans...

76 FR 63671 - Omaha Public Power District, Fort Calhoun Station, Unit 1; Exemption

Science.gov (United States)

2011-10-13

... significant effect on the quality of the human environment (January 3, 2011; 76 FR 187). This exemption is... Regulatory Commission. Michele G. Evans, Director, Division of Operating Reactor Licensing, Office of Nuclear...

75 FR 54694 - Notice of Availability of a Supplemental Draft Environmental Impact Statement for the...

Science.gov (United States)

2010-09-08

... Counsel of Environmental Quality (CEQ) regulations implementing NEPA (40 CFR parts 1500 et seq.) and FRA's... and additions, which include a new Victorville passenger station option at Dale Evans Parkway, a rail...

Refractive Development in the “ROP Rat”

Directory of Open Access Journals (Sweden)

Toco Y. P. Chui

2012-01-01

Full Text Available Although retinopathy of prematurity (ROP is clinically characterized by abnormal retinal vessels at the posterior pole of the eye, it is also commonly characterized by vascular abnormalities in the anterior segment, visual dysfunction which is based in retinal dysfunction, and, most commonly of all, arrested eye growth and high refractive error, particularly (and paradoxically myopia. The oxygen-induced retinopathy rat model of ROP presents neurovascular outcomes similar to the human disease, although it is not yet known if the “ROP rat” also models the small-eyed myopia characteristic of ROP. In this study, magnetic resonance images (MRIs of albino (Sprague-Dawley and pigmented (Long-Evans ROP rat eyes, and age- and strain-matched room-air-reared (RAR controls, were examined. The positions and curvatures of the various optical media were measured and the refractive state (℞ of each eye estimated based on a previously published model. Even in adulthood (postnatal day 50, Sprague-Dawley and Long-Evans ROP rats were significantly myopic compared to strain-matched controls. The myopia in the Long-Evans ROP rats was more severe than in the Sprague-Dawley ROP rats, which also had significantly shorter axial lengths. These data reveal the ROP rat to be a novel and potentially informative approach to investigating physiological mechanisms in myopia in general and the myopia peculiar to ROP in particular.

Markko Märtin : sain maailma parima kaardilugeja

Index Scriptorium Estoniae

2005-01-01

Markko Märtin rääkis ajakirjale Autosport traagilisest avariist ja hukkunud kaardilugejast Michael Parkist. Michael Parki meenutavad: Robert Reid, Paul Turner, Sebastien Loeb, David Higgins, Malcolm Wilson, Daniel Elena, David Evans

Social marketing campaigns and children's media use.

Science.gov (United States)

Evans, W Douglas

2008-01-01

Media-related commercial marketing aimed at promoting the purchase of products and services by children, and by adults for children, is ubiquitous and has been associated with negative health consequences such as poor nutrition and physical inactivity. But, as Douglas Evans points out, not all marketing in the electronic media is confined to the sale of products. Increasingly savvy social marketers have begun to make extensive use of the same techniques and strategies used by commercial marketers to promote healthful behaviors and to counter some of the negative effects of conventional media marketing to children and adolescents. Evans points out that social marketing campaigns have been effective in helping to prevent and control tobacco use, increase physical activity, improve nutrition, and promote condom use, as well as other positive health behaviors. He reviews the evidence from a number of major recent campaigns and programming in the United States and overseas and describes the evaluation and research methods used to determine their effectiveness. He begins his review of the field of social marketing by describing how it uses many of the strategies practiced so successfully in commercial marketing. He notes the recent development of public health brands and the use of branding as a health promotion strategy. He then goes on to show how social marketing can promote healthful behavior, how it can counter media messages about unhealthful behavior, and how it can encourage discussions between parents and children. Evans concludes by noting some potential future applications to promote healthful media use by children and adolescents and to mitigate the effects of exposure to commercial marketing. These include adapting lessons learned from previous successful campaigns, such as delivering branded messages that promote healthful alternative behaviors. Evans also outlines a message strategy to promote "smart media use" to parents, children, and adolescents and

On 20 November CERN hosted a symposium to mark the 70th birthday of Chris Llewellyn Smith

CERN Multimedia

Maximilien Brice

2012-01-01

Left to right: (back) Rolf Heuer, Peter Jenni, Lyn Evans, Chris Llewellyn Smith, Steve Cowley, Zehra Sayers, David Gross, Chris Allsopp, Robert Jaffe, Bikash Sinha; (front) Geoffrey West, Álvaro de Rújula, John Ellis.

In vitro inhibition of the paraoxonase from human serum with ...

African Journals Online (AJOL)

SERVER

2008-03-04

2000). ... Playfer JR, Eze CL, Bullen MF, Evans DAP (1976). Genetic polymor- phism and interethnic variability of plasma paraoxonase activity. J. Med. ... Senter PD, Marquardt H, Thomas BA, Hammock BD, Frank IS,. Svensson ...

Gallstones

Science.gov (United States)

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 155. Jackson PG, Evans SRT. Biliary system. In: Townsend CM ... 65. Review Date 4/19/2017 Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The ...

Acute cholecystitis

Science.gov (United States)

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 66. Jackson PG, Evans SRT. Biliary system. In: Townsend CM ... 65. Review Date 7/10/2017 Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The ...

77 FR 62539 - Dominion Nuclear Connecticut, Inc.; Millstone Power Station, Unit 2, Revocation of Exemption

Science.gov (United States)

2012-10-15

... that the revocation of this exemption will not have a significant effect on the quality of the human..., this 3rd day of October 2012. For the Nuclear Regulatory Commission. Michele G. Evans, Director...

Gallbladder removal - laparoscopic

Science.gov (United States)

... Gallbladder anatomy Laparoscopic surgery - series References Jackson PG, Evans SRT. Biliary system. In: Townsend CM Jr, Beauchamp ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Choledocholithiasis

Science.gov (United States)

... PA: Elsevier Saunders; 2016:chap 155. Jackson PG, Evans SRT. Biliary system. In: Townsend CM Jr, Beauchamp ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Gallbladder removal - open - discharge

Science.gov (United States)

... cholesys.ashx . Accessed August 9, 2016. Jackson PG, Evans SRT. Biliary System. In: Townsend CM Jr, Beauchamp ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Gallbladder removal - laparoscopic - discharge

Science.gov (United States)

... ncbi.nlm.nih.gov/pubmed/26119606 . Jackson PG, Evans SRT. Biliary System. In: Townsend CM Jr, Beauchamp ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Percutaneous transhepatic cholangiogram

Science.gov (United States)

... Images Gallbladder anatomy Bile pathway References Jackson PG, Evans SRT. Biliary system. In: Townsend CM Jr, Beauchamp ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Earlobe creases

Science.gov (United States)

... on the symptoms. Images Ear lobe crease References Evans K, Hing AV, Cunningham M. Craniofacial malformations. In: ... A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among ...

Physical, chemical, and deepwater current profiles collected from CTD, XBT, and ADCP moorings in the Eastern Gulf of Mexico from January 19, 2005 to January 28, 2006 (NODC Accession 0070922)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — A Minerals Management Service (MMS) program entitled Survey of Deepwater Currents in the Eastern Gulf of Mexico, awarded to Evans-Hamilton, Inc. This data set...

The cosmic microwave background how it changed our understanding of the universe

CERN Document Server

Evans, Rhodri

2015-01-01

Rhodri Evans tells the story of what we know about the universe, from Jacobus Kapteyn’s Island universe at the turn of the 20th Century, and the discovery by Hubble that the nebulae were external to our own galaxy, through Gamow’s early work on the cosmic microwave background (CMB) and its subsequent discovery by Penzias and Wilson, to modern day satellite-lead CMB research. Research results from the ground-based experiments DASI, BOOMERANG, and satellite missions COBE, WMAP and Planck are explained and interpreted to show how our current picture of the universe was arrived at, and the author looks at the future of CMB research and what we still need to learn. This account is enlivened by Dr Rhodri Evans' personal connections to the characters and places in the story.

MR imaging with Gd-DTPA enhancement in experimental acute injury of the spinal cord

International Nuclear Information System (INIS)

Hackney, D.B.; Asato, R.; Joseph, P.M.; McGrath, J.T.; Grossman, R.I.; Shetty, A.

1986-01-01

The authors performed MR imaging with Gd-DTPA enhancement in adult male Sprague-Dawley rats, with experimentally induced acute spinal cored injuries. After epidural compression of the spinal cored the pathologic changes of acute cord contusion were allowed to develop for 30 minutes to 4 hours. MR imaging was then performed at 1.4 T. Both short spin-echo (TR = 400 msec, TE = 15-20 msec) and long spin-echo (TR = 2,000 msec, TE = 100 msec) images were obtained. After the initial imaging, Gd-DTPA (0.1 mmol/kg) and Evans blue dye were administered intravenously and imaging was repeated. Enhancement of normal central gray matter was consistently observed. However, neither pathologic enhancement on MR images nor extravasation of Evans blue dye on histologic inspection were identified

Genetics Home Reference: spondyloepimetaphyseal dysplasia, Strudwick type

Science.gov (United States)

... White L, Hills N, Nicol M, Evans G, Cole T, Chapman S, Pope FM. A glycine to aspartic ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

Protection of marine birds and turtles at St Brandon's Rock, Indian ...

African Journals Online (AJOL)

Protection of marine birds and turtles at St Brandon's Rock, Indian Ocean, requires conservation of the entire atoll. SW Evans, N Cole, H Kylin, NS Choong Kwet Yive, V Tatayah, J Merven, H Bouwman ...

Laplace transforms and the American straddle

Directory of Open Access Journals (Sweden)

G. Alobaidi

2002-01-01

partial Laplace transform techniques due to Evans et al. (1950 to derive a pair of integral equations giving the locations of the optimal exercise boundaries for an American straddle option with a constant dividend yield.

Huntington's disease: the coming of age

Indian Academy of Sciences (India)

Pandey, Mritunjay (NIH/NIDDK) [E

The term 'Westphal variant' is often used to describe the clinical picture of juvenile HD. ... diagnoses recorded in general practice records (Evans SJ et al. ..... measures of strength, neurological status, or cognitive function (Verbessemet al.

Extensive regularization of the coupled cluster methods based on the generating functional formalism: Application to gas-phase benchmarks and to the SN2 reaction of CHCl3 and OH- in water

International Nuclear Information System (INIS)

Kowalski, Karol; Valiev, Marat

2009-01-01

The recently introduced energy expansion based on the use of generating functional (GF) [K. Kowalski and P. D. Fan, J. Chem. Phys. 130, 084112 (2009)] provides a way of constructing size-consistent noniterative coupled cluster (CC) corrections in terms of moments of the CC equations. To take advantage of this expansion in a strongly interacting regime, the regularization of the cluster amplitudes is required in order to counteract the effect of excessive growth of the norm of the CC wave function. Although proven to be efficient, the previously discussed form of the regularization does not lead to rigorously size-consistent corrections. In this paper we address the issue of size-consistent regularization of the GF expansion by redefining the equations for the cluster amplitudes. The performance and basic features of proposed methodology are illustrated on several gas-phase benchmark systems. Moreover, the regularized GF approaches are combined with quantum mechanical molecular mechanics module and applied to describe the S N 2 reaction of CHCl 3 and OH - in aqueous solution.

Download this PDF file

African Journals Online (AJOL)

Francis

Natural products from plants have been the basis of many treatments of human diseases that ..... Hill P, Evans CS & Veness RG (1997) Antimicrobial action of essential oils: the ... sonication extraction method of Hibiscus tiliaceus L. flowers.

towards creating a flexible evaluation design for academic literacy ...

African Journals Online (AJOL)

Kate H

teaching approaches, e.g. Dudley-Evans 1995)1, writing centres (e.g. .... for Higher Education and Training (ESLA-Plus) (Van Dyk and Weideman ..... for example, compared students' self-reported reading preparedness to their reading profiles as.

Neurodevelopmental malformations of the cerebellar vermis in genetically engineered rats

Science.gov (United States)

The cerebellar vermis is particularly vulnerable to neurodevelopmental malformations in humans and rodents. Sprague-Dawley, and Long-Evans rats exhibit spontaneous cerebellar malformations consisting of heterotopic neurons and glia in the molecular layer of the vermis. Malformati...

adicating African Wars:

African Journals Online (AJOL)

countries, African decision makers nonetheless began to reconsider the role and place of military ..... challenged the war—fighting paradigm for armed forces or the 2003 Gulf ..... Carlisle: Strategic Studies Institute, US Army War College. Evans ...

The effects of problem-based learning on pre-service teachers ...

African Journals Online (AJOL)

Critical thinking, one of the skills associated with thinking, is the evaluation of our .... means to explore or enhance that knowledge” (Belt, Hywel Evans, McCreedy, Overton ...... Navigating the bumpy road to student-centered instruction. College ...

Kiritimati Isotope (delta 13C, delta 18O, Sr/Ca) Data for 1938 to 1993

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The following is excerpted from Evans et al., J.Geophys. Res., in review, 1998 (please see this paper for references made in this readme file): Proxy climate data...

78 FR 60376 - Agency Information Collection Activities; Information Collection Renewal; Submission for OMB...

Science.gov (United States)

2013-10-01

... Currency, 400 7th Street SW., Suite 3E-218, Mailstop 9W-11, Washington, DC 20219. FDIC: Michael R. Evans... collection, including the validity of the methodology and assumptions used; (c) Ways to enhance the quality...

Kuulumatusest, prantsuse keeles : Buñuel, Villeneuve ja Audiard katusekinos / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2011-01-01

Katusekino maikuu programmis on Luis Buñueli "Päevane kaunitar" ("Belle de jour", Prantsusmaa-Itaalia 1967), Denis Villeneuve "Põlenud" ("Incendies", Kanada-Prantsusmaa 2010) ja Jacques Audiard´i "Prohvet" ("Un prophète", Prantsusmaa-Itaalia 2009)

Synthesis, microstructure and mechanical properties of ceria ...

Indian Academy of Sciences (India)

Unknown

ceria stabilized zirconia powders with improved mechanical properties. Ce–ZrO2 with 20 wt% ... structural ceramic materials (Garvie et al 1975; Evans and. Cannon 1986) ... thermal expansion matching with that of iron alloys. (Tsukuma and ...

Staying Ahead of Childhood Diseases (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

Many childhood diseases that used to cause epidemics in the United States are now rare thanks to vaccinations. In this podcast, Dr. Laurie Elam-Evans discusses the importance of keeping children up-to-date on recommended vaccinations.

Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD on Hormones of Energy Balance in a TCDD-Sensitive and a TCDD-Resistant Rat Strain

Directory of Open Access Journals (Sweden)

Jere Lindén

2014-08-01

Full Text Available One of the hallmarks of the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD is a drastically reduced feed intake by an unknown mechanism. To further elucidate this wasting syndrome, we followed the effects of a single large dose (100 μg/kg of TCDD on the serum levels of several energy balance-influencing hormones, clinical chemistry variables, and hepatic aryl hydrocarbon receptor (AHR expression in two rat strains that differ widely in their TCDD sensitivities, for up to 10 days. TCDD affected most of the analytes in sensitive Long-Evans rats, while there were few alterations in the resistant Han/Wistar strain. However, analyses of feed-restricted unexposed Long-Evans rats indicated several of the perturbations to be secondary to energy deficiency. Notable increases in ghrelin and glucagon occurred in TCDD-treated Long-Evans rats alone, which links these hormones to the wasting syndrome. The newly found energy balance regulators, insulin-like growth factor 1 and fibroblast growth factor 21 (FGF-21, appeared to function in concert in body weight loss-induced metabolic state, and FGF-21 was putatively linked to increased lipolysis induced by TCDD. Finally, we demonstrate a reverse set of changes in the AHR protein and mRNA response to TCDD and feed restriction, suggesting that AHR might function also as a physiological regulator, possibly involved in the maintenance of energy balance.

[Studies on transdermal delivery of ferulic acid through rat skin treated by microneedle arrays].

Science.gov (United States)

Yang, Bing; Du, Shou-ying; Bai, Jie; Shang, Ke-xin; Lu, Yang; Li, Peng-yue

2014-12-01

In order to investigate the characteristics of transdermal delivery of ferulic acid under the treated of microneedle arrays and the influence on permeability of rat skin capillaries, improved Franz-cells were used in the transdermal delivery experiment with the rat skin of abdominal wall and the length of microneedle arrays, different insertion forces, retention time were studied in the influence of characteristics of transdermal delivery of FA. The amount of FA was determined by HPLC system. Intravenous injection Evans blue and FA was added after microneedle arrays treated. Established inflammation model was built by daubing dimethylbenzene. The amount of Evans blue in the rat skin was read at 590 nm wavelength with a Multiskan Go microplate reader. Compared with passive diffusion group the skin pretreated with microneedle arrays had a remarkable enhancement of FA transport (P Microneedle arrays with different length had a remarkable enhancement of FA transport, but was not related to the increase of the length. The research of FA on the reduce of permeability of rat skin capillaries indicated that the skin pretreated with microneedle arrays could reduce the content of Evans blue in the skins of rat significantly compared with the untreated group. The permeation rate of ferulic acid transdermal delivery had remarkable increase under the treated of microneedle arrays and the length of microneedle arrays ,the retention time so as to the insertion force were important to the transdermal delivery of ferulic acid.

The intersection between Descriptivism and Meliorism in reasoning research: further proposals in support of 'soft normativism'.

Science.gov (United States)

Stupple, Edward J N; Ball, Linden J

2014-01-01

The rationality paradox centers on the observation that people are highly intelligent, yet show evidence of errors and biases in their thinking when measured against normative standards. Elqayam and Evans' (2011) reject normative standards in the psychological study of thinking, reasoning and deciding in favor of a 'value-free' descriptive approach to studying high-level cognition. In reviewing Elqayam and Evans' (2011) position, we defend an alternative to descriptivism in the form of 'soft normativism,' which allows for normative evaluations alongside the pursuit of descriptive research goals. We propose that normative theories have considerable value provided that researchers: (1) are alert to the philosophical quagmire of strong relativism; (2) are mindful of the biases that can arise from utilizing normative benchmarks; and (3) engage in a focused analysis of the processing approach adopted by individual reasoners. We address the controversial 'is-ought' inference in this context and appeal to a 'bridging solution' to this contested inference that is based on the concept of 'informal reflective equilibrium.' Furthermore, we draw on Elqayam and Evans' (2011) recognition of a role for normative benchmarks in research programs that are devised to enhance reasoning performance and we argue that such Meliorist research programs have a valuable reciprocal relationship with descriptivist accounts of reasoning. In sum, we believe that descriptions of reasoning processes are fundamentally enriched by evaluations of reasoning quality, and argue that if such standards are discarded altogether then our explanations and descriptions of reasoning processes are severely undermined.

Activation of retinal stem cells in the proliferating marginal region of RCS rats during development of retinitis pigmentosa.

Science.gov (United States)

Jian, Qian; Xu, Haiwei; Xie, Hanping; Tian, Chunyu; Zhao, Tongtao; Yin, ZhengQin

2009-11-06

Retinal stem cells (RSCs) have been demonstrated at the proliferating marginal regions from the pars plana of ciliary body to the ciliary marginal zone (CMZ) in adult lower vertebrates and mammals. Investigations in the lower vertebrates have provided some evidence that RSCs can proliferate following retinal damage; however, the evidence that this occurs in mammals is not clear. In this study, we explored RSCs proliferation potential of adult mammalian in proliferating marginal regions of Royal College of Surgeons (RCS) rats, an animal model for retinitis pigmentosa (RP). The proliferation was evaluated using BrdU labeling, and Chx-10 as markers to discern progenitor cell of CMZ in Long-Evan's and RCS rats at different postnatal day (PND) after eye opening. We found that few Chx-10 and BrdU labeled cells in the proliferating marginal regions of Long-Evan's rats, which significantly increased in RCS rats at PND30 and PND60. Consistent with this, Chx-10/Vimentin double staining cells in the center retina of RCS rats increased significantly at PND30 after eye opening. In addition, mRNA expression of Shh, Ptch1 and Smo was up-regulated in RCS rats at PND60 compared to age-matched Long-Evan's rats, which revealed Shh/ptc pathway involving in the activation of RSCs. These results suggest that RSCs in the mammalian retinal proliferating marginal regions has the potential to regenerate following degeneration.

Effect of Day-Studentship on Study of Geography among Female ...

African Journals Online (AJOL)

User

2011-04-19

Apr 19, 2011 ... Management, Faculty of Environmental Sciences, Evan Enwerem ... According to Okeke (1985), organizational efficiency of secondary ... systems approach to educational administration attempts to view the school ..... Sherlekar, S.A. (1984) Modern Business Organization and Management: Systems-.

DIFFERENTIAL EFFECTS OF CAFFEINE, PICROTOXIN, AND PENTYLENETETRAZOL ON HIPPOCAMPAL AFTERDISCHARGE ACTIVITY AND WET DOG SHAKES (JOURNAL VERSION)

Science.gov (United States)

The present experiment was conducted to identify changes in hippocampal after discharge (AD) parameters following administration of subconvulsant dosages (half of the convulsant dosage) of analeptics with known pharmacological action. Long Evans rats (N=104) with chronic bipolar ...

INCORPORATION OF MECHANISTIC INFORMATION IN THE ARSENIC PBPK MODEL DEVELOPMENT PROCESS

Science.gov (United States)

INCORPORATING MECHANISTIC INSIGHTS IN A PBPK MODEL FOR ARSENICElaina M. Kenyon, Michael F. Hughes, Marina V. Evans, David J. Thomas, U.S. EPA; Miroslav Styblo, University of North Carolina; Michael Easterling, Analytical Sciences, Inc.A physiologically based phar...

Computed tomography of the brain in the diagnosis of and prognosis in normal pressure hydrocephalus

International Nuclear Information System (INIS)

Wikkelsoe, C.; Blomstrand, C.; Andersson, H.; Matousek, M.; Svendsen, P.

1989-01-01

Thirty-eight patients with normal pressure hydrocephalus were examined by CT before and after a ventriculo-peritoneal shunt operation. Evans ratio, periventricular hypodensity and width of hemispheric sulci, sylvian fissures, cella media, temporal horns and third and fourth ventricle were examined. Twenty-eight patients improved after the operation while 10 were unchanged (non responders). Those patients who improved had more often enlarged third ventricle, enlarged temporal horns and normal sylvian fissures than those who did not improve. No single CT parameter or combination of CT parameters alone could identify responders and non-responders. The ventriculo-peritoneal shunt operation reduced ventricular size (Evans ratio, cella media width), abolished periventricular hypodensity and reduced width of the temporal horns and third ventricle in both responders and non-responders. Reduction of the width of the third ventricle correlated to clinical improvement. (orig.)

EINSTEIN EQUATIONS FOR TETRAD FIELDS ECUACIONES DE EINSTEIN PARA CAMPOS TETRADOS

Directory of Open Access Journals (Sweden)

Héctor Torres-Silva

2008-11-01

Full Text Available Every metric tensor can be expressed by the inner product of tetrad fields. We prove that Einstein's equations for these fields have the same form as the stress-energy tensor of electromagnetism if the total external current . Using the Evans' unified field theory, we show that the true unification of gravity and electromagnetism is with source-free Maxwell equations.Todo tensor métrico puede ser expresado por el producto interno de campos tetrados. Se prueba que las ecuaciones de Einstein para esos campos tienen la misma forma que el tensor electromagnético de momento-energía si la corriente externa total es igual a cero. Usando la teoría de campo unificado de Evans se muestra que la verdadera unificación de la gravedad y el electromagnetismo es con las ecuaciones de Maxwell sin fuentes.

Pion-pair formation and the pion dispersion relation in a hot pion gas

Energy Technology Data Exchange (ETDEWEB)

Chanfay, G. [Lyon-1 Univ., 69 - Villeurbanne (France). Inst. de Physique Nucleaire; Alm, T. [Rostock Univ. (Germany); Schuck, P. [Grenoble-1 Univ., 38 (France). Inst. des Sciences Nucleaires; Welke, G. [Wayne State Univ., Detroit, MI (United States). Dept. of Physics and Astronomy

1996-09-01

The possibility of pion-pair formation in a hot pion gas, based on the bosonic gap equation, is pointed out and discussed in detail. The critical temperature for condensation of pion pairs (Evans-Rashind transition) is determined as a function of the pion density. As for fermions, this phase transition is signaled by the appearance of a pole in the two-particle propagator. In Bose systems there exists a second, lower critical temperature, associated with the appearance of the single-particle condensate. Between the two critical temperatures the pion dispersion relation changes from the usual quasiparticle dispersion to a Bogoliubov-like dispersion relation at low momenta. This generalizes the non-relativistic results for an attractive Bose gas by Evans et al. Possible consequences for the inclusive pion spectra measured in heavy-ion collisions at ultra-relativistic energies are discussed. 21 refs.

LETTERS OF MARIA KUNCEWICZOWA TO HER LATE HUSBAND

Directory of Open Access Journals (Sweden)

Anna Wzorek

2017-04-01

Full Text Available The article discusses the last book of Maria Kuncewiczowa – a set of twenty-three letters (provided with a postscript addressed to her deceased husband. The uniqueness of this correspondence, presented in literary form, lies in the fact that the recipient is dead, treated by the sender as someone constantly present in the real world and still associated with the temporality. "Listy do Jerzego" ("Letters to Jerzy" are – as Tadeusz Swat, one of the reviewers say – “an attempt at denial of death, to save Jerzy by love, memory, and literature.” The analysis of the work highlights the occurring axiological categories. It has been demonstrated that "Letters to Jerzy" is a book about eternal love reaching beyond the grave (in this respect, in stark contrast with "Tristan" 1946, felt with dignity of old age, and finally transcending into faith. "Letters to Jerzy" is also an attempt to reduce the suffering of the writer over the loss of her beloved husband. To some extent, therefore, they correspond to her earlier work "Cudzoziemka" ("Foreigner" in which Kuncewiczowa liberates from the negative emotions associated with the death of her mother.

Euroopa tasakaal / Ela Tomson

Index Scriptorium Estoniae

Tomson, Ela, 1945-

2006-01-01

Vt. ka Postimees : na russkom jazõke 13. juuli lk. 7. Parlamendiliikme sõnul on vajadus leida tasakaal kultuuriliste ja religioossete erinevuste vahel Euroopa riikide sisepoliitika igapäevane osa ning Venemaa poliitikutel tuleb paratamatult tunnistada integratsiooniprotsessi edukust Eestis

76 FR 56471 - Membership of the Senior Executive Service Standing Performance Review Boards

Science.gov (United States)

2011-09-13

... DIRECTOR, PROCUREMENT SERVICES STAFF. JORDAN, WYEVETRA APPROPRIATION LIAISON OFFICER. MORGAN, MELINDA B... ETHICS OFFICE. TOSCANO JR., RICHARD A DIRECTOR, EQUAL EMPLOYMENT OPPORTUNITY STAFF. National Drug..., APPELLATE UNIT. EVANS, STUART DEPUTY CHIEF, OPERATIONS SECTION. KAYE, JANICE A ETHICS OFFICER. KEEGAN...

Phytochemical constituents and effects of aqueous root-bark extract ...

African Journals Online (AJOL)

PRECIOUS

2009-11-02

Nov 2, 2009 ... tional medicinal uses in the treatment of snake bites, jaundice, chest pains, dysentery, .... ties of this plant for the treatment of psychiatry disease as claimed by traditional ... Royal Botanical Garden Kew. pp. 415-440. Evans WC ...

Algamas on "Kahe ilu festival" / Silja Joon

Index Scriptorium Estoniae

Joon, Silja, 1966-

2008-01-01

Pärnus 14.-16. novembrini kestva kirjanduse ja muusika festivali "Kahe ilu festival" eelinfo - korraldavad Vaimse Rutiini Preventsiooni Sihtasutus, Kultuurilabor, Pärnu ooper ja Kunstide Maja, festivali raames toimub luulemaraton ning kõnekoosolek "Meie igapäevane põrgu"

Diplodia natalensis Pole Evans, the causal agent of citrus gummosis ...

African Journals Online (AJOL)

The isolation media used were 1.5 per cent water agar, 1.5 per cent water agar + nystatin, and 1.5 per cent water agar + benomyl. ... When the isolates were tested for pathogenicity, only D. natalensis induced the disease symptoms in the inoculated 18-month-old rough lemon seedlings which were incubated after ...

Ajaleheturul on 70% allahindlus igapäevane / Eda-Liis Kann

Index Scriptorium Estoniae

Kann, Eda-Liis, 1979-

2004-01-01

Selle asemel, et ametlikult reklaamihinda langetada pakuvad ajalehed reklaamiandjatele ülisuuri soodustusi. Kommenteerivad Enn Parel, Aavo Kokk, Andrus Vaher, Priit Leito, Erik Roose, Ruta Kallaspoolik, Toomas Tiivel, Lauri-Hillar Talve

Optimizing the Internal Medicine Clinic at Evans Army Community Hospital

National Research Council Canada - National Science Library

Bonilla, Jose

2003-01-01

Although the Department of Defense (DoD) has established access to care standards for military health care organizations and their treatment facilities, many facilities may face challenges in meeting these standards. In fiscal year (FY...

DCS Hydrology Submission for Evans County GA MapMod08

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

Kaali saladus - pühapäevane maiuspala / Inge Pitsner

Index Scriptorium Estoniae

Pitsner, Inge

2003-01-01

ETV näitab populaarteaduslikku filmi Kaali meteoriidiplahvatusest "Kaali saladus" : stsenarist ja režissöör Urmas E. Liiv : operaator Ago Ruus : produtsent Riho Västrik : OÜ Vesilind (Eesti) - Vides Filmu Studija (Läti)

The nature of the active site in heterogeneous metal catalysis

DEFF Research Database (Denmark)

Nørskov, Jens Kehlet; Bligaard, Thomas; Larsen, Britt Hvolbæk

2008-01-01

This tutorial review, of relevance for the surface science and heterogeneous catalysis communities, provides a molecular-level discussion of the nature of the active sites in metal catalysis. Fundamental concepts such as "Bronsted-Evans-Polanyi relations'' and "volcano curves'' are introduced...

6. Book Reviews

Directory of Open Access Journals (Sweden)

Enrico Pasini

2015-08-01

Full Text Available Reviews of Valery Rees, From Gabriel to Lucifer: A Cultural History of Angels, London-New York 2012; G. R. Evans, First Light. A History of Creation Myths from Gilgamesh to the God Particle, London-New York 2014.

Au Kenya, des oiseaux nuisent à une culture adaptée au climat ...

International Development Research Centre (IDRC) Digital Library (Canada)

23 août 2013 ... Selon Evans Kituyi, spécialiste de programme principal au Centre de ... principal au Gadam Sorghum Production and Marketing Project. Si les graines occupent une place de premier plan dans l'alimentation des oiseaux, ...

Agro. no 1 June Latest

African Journals Online (AJOL)

The rats were divided into five treatment dose levels; 0 (5.0 ml saline); 5.0; ..... Drumstick (Moringa oleifera): a multipurpose Indian vegetable. Econ. Bot.34 ... Trease, G. E and Evans, W. C. (1985): Textbook of Pharmacognozy, 12 Ed. Ballimore.

Inimõigustest lepingulise loobumise seaduslikkuse standard Euroopa inimõiguste ja põhivabaduste kaitse konventsiooni kontekstis / Heidi Rajamäe-Parik

Index Scriptorium Estoniae

Rajamäe-Parik, Heidi

2011-01-01

Inimõigustest loobumisest kui kahe õiguse kollisioonist. Euroopa Inimõiguste Kohtu lahendist Evans vs. Ühendkuningriik. Artikkel on lühiülevaade autori magistritööst "Legality of a contractual waiver of human rights in the European context"

F.F.F.F. armastab mõtestada ennast / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

2002-01-01

Rühmituse F.F.F.F. (Kristi Paap, Kaire Rannik, Berit Teeäär, Ketli Tiitsar, Maria Valdma) näitus "Meie igapäevane leib" 9. novembrini Hansapanga galeriis ja näitus "Pentagramm" 26. X-1. XII Tarbekunstimuuseumis

Should We Stay or Should We Go Now? The Physical, Economic, Geopolitical, Social and Psychological Factors of Recovery from Catastrophic Disaster

Science.gov (United States)

2014-09-01

Histoire d’aujourd’hui (Paris: Larousse, 2008). 54 Graham Evans and Jeffrey Newnham, The Penguin Dictionary of International Relations (London...Géopolitique: La Longue Histoire d’aujourd’hui. Paris: Larousse, 2008. Lammers, Cornelis Jacobus. Survey of Evacuation Problems and Disaster

JCSC_128_5_707-718_SI.docx

Indian Academy of Sciences (India)

MMC14

Quantum chemical study of the mechanisms of oxidation of ethylene by Molybdyl and Tungstyl Chloride. RICHARD TIA*, EVANS ADEI, JOSEPH BAIDOO and JULIANA EDOR. Theoretical and Computational Chemistry Laboratory, Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, ...

Nazvanõ pobediteli "Kinonagradõ MTV Rossija"

Index Scriptorium Estoniae

2006-01-01

Telekanali MTV Rossija filmiauhind läks Timur Bekmambetovi filmile Sergei Lukjanenko triloogia järgi "Päevane patrull" ("Dnevnoi dozor"). Parima näitleja auhinna said Aleksei Tshadov ja Zhanna Friske. Eriauhind "Põlvkonna tunnustus" anti postuumselt Sergei Bodrov nooremale

Multiple condensed phases in attractively interacting Bose systems

Czech Academy of Sciences Publication Activity Database

Männel, M.; Morawetz, K.; Lipavský, Pavel

2010-01-01

Roč. 12, č. 3 (2010), 033013/1-033013/9 ISSN 1367-2630 Institutional research plan: CEZ:AV0Z10100521 Keywords : Bose gas * T-matrix * Evan-Rashid transition Subject RIV: BE - Theoretical Physics Impact factor: 3.849, year: 2010

Bagatellid : maailm / Nele-Eva Steinfeld

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2008-01-01

Akadeemik Jarvis väidab, et osade Bachi teoste autoriks on hoopis helilooja naine Anna Magdalena. Pianist Andras Schiff pälvis Wigmore'i medali. Lahkus tenor Gianni Raimondi. Louvre ja tänapäevane muusikaelu. Uus esiviiul Juliardi keelpillikvartetis

78 FR 40516 - Sunshine Act Meetings

Science.gov (United States)

2013-07-05

... hear from a panel of policy experts on new models of workplace accommodations, including Chai Feldblum, Commissioner, Equal Employment Opportunity Commission; John Evans, WA Vocational Rehabilitation Employer..., NCD will receive public comment from individuals interested in focusing their remarks on workplace...

Teen Vaccines (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

No child should miss the opportunity for lasting protection against dangerous infectious diseases and some cancers, but unfortunately, many do. In this podcast, Dr. Laurie Elam-Evans discusses the importance of ensuring teenagers are up-to-date on their vaccinations.

Identification of fipronil metabolites in rodents by time-of-flight mass spectrometry for application in a human exposure study

Science.gov (United States)

Fipronil is a phenylpyrazole insecticide commonly used in residential and agricultural applications. To understand more about the potential risks associated with fipronil, dosed Long Evans rats were evaluated for metabolites to develop a set of biomarkers for use in human exposur...

Effect of sowing techniques and harvesting treatments on the ...

African Journals Online (AJOL)

hope&shola

2000-01-07

Jan 7, 2000 ... pasture lands and very limited forage crop production. Uncontrolled .... on the cover rate was also recorded and average cover rate in same-rows was .... on rye grass persistency and tillering, Evans et al. (1998) revealed that ...

CCAA Learning Paper 1 Integrating meteorological and indigenous ...

International Development Research Centre (IDRC) Digital Library (Canada)

2011-03-29

Mar 29, 2011 ... Contributing authors: Ignitius Chagonda; Jacob Churi; Amadou Dieye; Boris Houenou; Said Hounkponou; Eric Kisiangani; Evans Kituyi; Cromwel Lukorito; Ayub Macharia; Henry Mahoo; Amos Majule; Paul Mapfumo; Florence Mtambanengwe; Francis Mugabe; Laban Ogallo; Gilbert Ouma; Amadou Sall; ...

Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese ...

African Journals Online (AJOL)

Legislative Exclusions or Exemptions of Property from the Insolvent Estate · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. RG Evans. http://dx.doi.org/10.4314/pelj.v14i5.3 ...

IEEE International Semiconductor Laser Conference (14th) Held in Maui, Hawaii on September 19-23, 1994

Science.gov (United States)

1994-09-23

subcommittee chairs, Tom Koch, James Whiteaway and Yasuhiko Arakawa, for their efforts. The other Conference Committee members, Gary Evans, Joanne...Academy of Sciences, St. Petersburg, Russia Asia end Ausat/agla K. Ikeda Chair: Yasuhiko Arakawa Mitsubishi Electric Corporation, Hyogo, Japan University

Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis

Science.gov (United States)

Linden, Melissa A.; Sheldon, Ryan D.; Meers, Grace M.; Ortinau, Laura C.; Morris, E. Matthew; Booth, Frank W.; Kanaley, Jill A.; Vieira‐Potter, Victoria J.; Sowers, James R.; Ibdah, Jamal A.; Thyfault, John P.; Laughlin, M. Harold

2016-01-01

Key points Physiologically relevant rodent models of non‐alcoholic steatohepatitis (NASH) that resemble the human condition are limited.Exercise training and energy restriction are first‐line recommendations for the treatment of NASH.Hyperphagic Otsuka Long–Evans Tokushima fatty rats fed a western diet high in fat, sucrose and cholesterol for 24 weeks developed a severe NASH with fibrosis phenotype.Moderate intensity exercise training and modest energy restriction provided some improvement in the histological features of NASH that coincided with alterations in markers of hepatic stellate cell activation and extracellular matrix remodelling.The present study highlights the importance of lifestyle modification, including exercise training and energy restriction, in the regulation of advanced liver disease. Abstract The incidence of non‐alcoholic steatohepatitis (NASH) is rising but the efficacy of lifestyle modifications to improve NASH‐related outcomes remain unclear. We hypothesized that a western diet (WD) would induce NASH in the Otsuka Long–Evans Tokushima Fatty (OLETF) rat and that lifestyle modification would improve this condition. Eight‐week‐old Long–Evans Tokushima Otsuka (L) and OLETF (O) rats consumed a control diet (10% kcal fat, 3.5% sucrose) or a WD (45% kcal fat, 17% sucrose, 1% cholesterol) for 24 weeks. At 20 weeks of age, additional WD‐fed OLETFs were randomized to sedentary (O‐SED), food restriction (O‐FR; ∼25% kcal reduction vs. O‐SED) or exercise training (O‐EX; treadmill running 20 m min–1 with a 15% incline, 60 min day–1, 5 days week–1) conditions for 12 weeks. WD induced a NASH phenotype in OLETFs characterized by hepatic fibrosis (collagen 1α1 mRNA and hydroxyproline content), as well as elevated inflammation and non‐alcoholic fatty liver disease activity scores, and hepatic stellate cell activation (α‐smooth muscle actin) compared to Long–Evans Tokushima Otsuka rats. FR and EX modestly

Predicting dermal penetration for ToxCast chemicals using in silico estimates for diffusion in combination with physiologically based pharmacokinetic (PBPK) modeling.

Science.gov (United States)

Predicting dermal penetration for ToxCast chemicals using in silico estimates for diffusion in combination with physiologically based pharmacokinetic (PBPK) modeling.Evans, M.V., Sawyer, M.E., Isaacs, K.K, and Wambaugh, J.With the development of efficient high-throughput (HT) in ...

LBS Management Review - Vol 4, No 1 (1999)

African Journals Online (AJOL)

dx.doi.org/10.4314/lbsmr.v4i1.24463 · Leveraging your Database for Effective Direct Marketing. Vincent Onyemah. http://dx.doi.org/10.4314/lbsmr.v4i1.24464 · A Measurement Approach for Process Improvement. Evans Woherem.

Use of Electroencephalography (EEG) to Assess CNS Changes Produced by Pesticides with different Modes of Action: Effects of Permethrin, Deltamethrin, Fipronil, Imidacloprid, Carbaryl, and Triadimefon

Science.gov (United States)

The electroencephalogram (EEG) is an apical measure, capable of detecting changes in brain neuronal activity produced by internal or external stimuli. We assessed whether pesticides with different modes of action produced different changes in the EEG of adult male Long-Evans rats...

Les idées qui ont changé le monde: Maurice Lacroix célèbre les grands inventeurs de notre temps (1/2 page)

CERN Multimedia

2007-01-01

Maurice Lacroix wanted to underline the research and development work by making portraits of selected personalities who managed, with their perseverance and their capacity of innovation, to push away the limits of their field of work (ex. Lyndon Evans) (1/2 page)

Original Research Original Research

African Journals Online (AJOL)

RAGHAVENDRA

English well; graduates who join the world of wo to write their own CV ..... chosen for the study purposively because they were new to the schools and ..... Ababa, Semien Hotel. Evans, H. M. (1998). ... the Brink of Collapse. Elanders Gotab AB: ...

Direct NO decomposition over stepped transition-metal surfaces

DEFF Research Database (Denmark)

Falsig, Hanne; Bligaard, Thomas; Christensen, Claus H.

2007-01-01

We establish the full potential energy diagram for the direct NO decomposition reaction over stepped transition-metal surfaces by combining a database of adsorption energies on stepped metal surfaces with known Bronsted-Evans-Polanyi (BEP) relations for the activation barriers of dissociation...

Soy compared with milk protein in a western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats

Science.gov (United States)

Soy protein is effective at preventing hepatic steatosis; however, the mechanisms are poorly understood. We tested the hypothesis that soy versus dairy protein-based diet would alter microbiota and attenuate hepatic steatosis in hyperphagic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Male OLETF ...

Conference Report on the Future of Maritime Strategy (April 1, 1980) and Geopolitics and Maritime Power (September 17-18, 1980),

Science.gov (United States)

1980-01-01

Assistant Director for Long Range Planning, Off/CNO Rowland EVANS, Jr. - Syndicated Columnist Donald GENTRY - Office/Chief Naval Operations (OP 965...Headquarters Paul NITZE - Former Secretary of the Navy Robert NOVAK - Syndicated Columnist John O’SHAUGHNESSY - House Budget Committee Norman POLMAR

Defending Champions Reign Supreme at 2017 Student Science Jeopardy Tournament | Poster

Science.gov (United States)

Anuk Dayaprema and Evan Yamaguchi, champions of the 2016 Student Science Jeopardy Tournament, have done it again. After a grueling competition, they emerged victorious for the second year in a row at the 2017 Student Science Jeopardy Tournament, sponsored by the Scientific Library.

Stability of bumps in piecewise smooth neural fields with nonlinear adaptation

KAUST Repository

Kilpatrick, Zachary P.; Bressloff, Paul C.

2010-01-01

associated with a bump solution means that bump stability cannot be analyzed by constructing the Evans function for a network with a sigmoidal gain function and then taking the high-gain limit. In the case of synaptic depression, we show that linear stability

Halim et al, Afr J Tradit Complement Altern Med. (2018) 15 (2): 19 ...

African Journals Online (AJOL)

user

2018-02-23

Feb 23, 2018 ... He L, Fong J, von Zastrow M, Whistler JL. (2002). Regulation ... Keith DE, Murray SR, Zaki PA, Chu PC, Lissin DV, Kang L, Evans CJ, von Zastrow M. (1996). Morphine activates ... Tao PL, Lee HY, Chang LR, Loh HH. (1990).

USE OF SENSITIVITY ANALYSIS ON A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR CHLOROFORM IN RATS TO DETERMINE AGE-RELATED TOXICITY

Science.gov (United States)

USE OF SENSITIVITY ANALYSIS ON A PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR CHLOROFORM IN RATS TO DETERMINE AGE-RELATED TOXICITY.CR Eklund, MV Evans, and JE Simmons. US EPA, ORD, NHEERL, ETD,PKB, Research Triangle Park, NC. Chloroform (CHCl3) is a disinfec...

Toward a TQM Paradigm: Using SERVQUAL to Measure Library Service Quality.

Science.gov (United States)

Coleman, Vicki; And Others

1997-01-01

Texas A&M University's Evans Library conducted a survey (SERVQUAL) to measure service quality in terms of tangibles (appearance of facilities, equipment, personnel, and communication materials), reliability, responsiveness, assurance, and empathy. Discrepancies between expectations and perceptions were found in reliability, responsiveness,…

POLLUTION PREVENTION OPPORTUNITY ASSESSMENT HISTOLOGY LABORATORY XYLENE USE - FORT CARSON, COLORADO

Science.gov (United States)

Under the WREAFS program, RREL has performed a waste minimization opportunity assessment (WMOA) at the Evans Community Hospital Histopathology Laboratory on the Ft. Carson Army Base, Colorado, in the area of waste xylene and ethyl alcohol contaminated with human tissue. The waste...

African Journal of AIDS Research - Vol 8, No 3 (2009)

African Journals Online (AJOL)

Recommendations for communication to enhance informed consent and enrolment at multilingual research sites · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Claire Penn, Melanie Evans. http://dx.doi.org/10.2989/AJAR.2009.8.3.5.926 ...

Programmed cell death of tobacco BY-2 cells induced by still culture conditions is affected by the age of the culture under agitation.

Science.gov (United States)

Hiraga, Asahi; Kaneta, Tsuyoshi; Sato, Yasushi; Sato, Seiichi

2010-01-25

Evans Blue staining indicated that actively growing tobacco BY-2 cells in the exponential phase died more rapidly than quiescent cells in the stationary phase when the cells cultured under agitation were placed under still conditions. Fifty percent cell death was induced at about 18, 26, 80 and 140 h for early, mid, late exponential- and stationary-phase cells, respectively. Actively growing cells became TUNEL (transferase-mediated dUTP nick end labelling)-positive more rapidly than quiescent cells, suggesting that the cell death evaluated by Evans Blue is accompanied by DNA cleavages. Electrophoresis of genomic DNA showed a typical 'DNA laddering' pattern formed by multiples of about 200 bp internucleosomal units. Chromatin condensation was first detected at least within 24 h by light microscopy, and then cell shrinkage followed. These findings suggest that the death of BY-2 cells induced by still conditions is PCD (programmed cell death).

Microwave hyperthermia-induced blood-brain barrier alterations

International Nuclear Information System (INIS)

Lin, J.C.; Lin, M.F.

1982-01-01

We have studied the interaction of microwaves with the blood-brain barrier in Wistar rats. Indwelling catheters were placed in the femoral vein. Evans blue in isotonic saline was used as a visual indicator of barrier permeation. Irradiation with pulsed 2450-MHz microwaves for 20 min at average power densities of 0.5 to 2600 mW/cm 2 , which resulted in average specific absorption rages (SARs) of 0.04 to 200 mW/g in the brain, did not produce staining, except in regions that normally are highly permeable. When the incident power density was increased to 3000 mW/cm 2 (SAR of 240 mW/g), extravasation of Evans blue could be seen in the cortex, hippocampus, and midbrain. The rectal temperature, as monitored by a copper-constantan thermocouple, showed a maximum increase of less than 1.0/sup o/C. the brain temperature recorded in a similar group of animals using a non-field-perturbing thermistor exceeded 43/sup o/C. At the higher power density the extravasation depended on the irradition and euthanization times. In one series of experiments, rats were irradiated at 3000 mW/cm 2 for 5, 10, 15, and 20 min. Immediately after irradiation all except the 5-min animals exhibited increased permeability in some regions of the brain. Brains of rats euthanized 30 min after irradiation were free of Evans blue, while those euthanized 10 and 20 min postirradiation showed significant dye staining but with less intensity than those euthanized immediately after irradiation

R-Modafinil Attenuates Nicotine-Taking and Nicotine-Seeking Behavior in Alcohol-Preferring Rats

Science.gov (United States)

Wang, Xiao-Fei; Bi, Guo-Hua; He, Yi; Yang, Hong-Ju; Gao, Jun-Tao; Okunola-Bakare, Oluyomi M; Slack, Rachel D; Gardner, Eliot L; Xi, Zheng-Xiong; Newman, Amy Hauck

2015-01-01

(±)-Modafinil (MOD) is used clinically for the treatment of sleep disorders and has been investigated as a potential medication for the treatment of psychostimulant addiction. However, the therapeutic efficacy of (±)-MOD for addiction is inconclusive. Herein we used animal models of self-administration and in vivo microdialysis to study the pharmacological actions of R-modafinil (R-MOD) and S-modafinil (S-MOD) on nicotine-taking and nicotine-seeking behavior, and mechanisms underlying such actions. We found that R-MOD is more potent and effective than S-MOD in attenuating nicotine self-administration in Long–Evans rats. As Long–Evans rats did not show a robust reinstatement response to nicotine, we used alcohol-preferring rats (P-rats) that display much higher reinstatement responses to nicotine than Long–Evans rats. We found that R-MOD significantly inhibited intravenous nicotine self-administration, nicotine-induced reinstatement, and nicotine-associated cue-induced drug-seeking behavior in P-rats. R-MOD alone neither sustained self-administration in P-rats previously self-administering nicotine nor reinstated extinguished nicotine-seeking behavior. The in vivo brain microdialysis assays demonstrated that R-MOD alone produced a slow-onset moderate increase in extracellular DA. Pretreatment with R-MOD dose-dependently blocked nicotine-induced dopamine (DA) release in the nucleus accumbens (NAc) in both naive and nicotine self-administrating rats, suggesting a DA-dependent mechanism underlying mitigation of nicotine's effects. In conclusion, the present findings support further investigation of R-MOD for treatment of nicotine dependence in humans. PMID:25613829

CHANGES IN NEUROTRANSMITTER GENE EXPRESSION IN THE AGING RETINA.

Science.gov (United States)

To understand mechanisms of neurotoxicity in susceptible populations, we examined age-related changes in constitutive gene expression in the retinas of young (4mos), middle-aged (11 mos) and aged (23 mos) male Long Evans rats. Derived from a pouch of the forebrain during develop...

some nutritional aspects of haemonchosis in experimentally infested ...

African Journals Online (AJOL)

nutritional aberration has been described as anorexia in both pure (Evans, Blunt & Southcott, 1963) and mixed infestations where Haemonchus contortus was prominent. (Clark, Ortlepp, Bosman, Laurence, Groenewald & Quin,. 1951; Shumard et al. 1957). Further observations on nutritional aspects of a pure infestation of ...

Zhit v televizore opasnei vsehh boleznei

Index Scriptorium Estoniae

2004-01-01

Briti teadlaste (King's College) Tim Crayford'i, Richard Hooper'i ja Sarah Evans'i poolt läbi viidud uurimusest, milles nad tegid statistikat teleseriaalide kangelaste surmapõhjuste, sünnituste, psüühhiliste häirete kohta. Kommentaar ka arst Sarah Clement'ilt

On 10 November, the first sector of the LHC was completely interconnected.

CERN Multimedia

2006-01-01

Sector 7-8 became the first one ready for operation. The LHC project leader Lyn Evans, the teams involved in this achievement from CERN's group AT/MCS, AT/VAC and AT/MEL and members of the IEG consortium are shown in the 7-8 sector.

Glucose oxidase production does not increase after colony infection: Testing its role in honey bee social immunity

Science.gov (United States)

Honey bees rely on a variety of defense mechanisms to reduce disease infection and spread throughout the colony. Hygienic behavior, resin collection, and antimicrobial peptide production are some examples of defenses that bees use against parasites (Evans & Spivak, 2010 J Invertebr Pathol 103:S62). ...

The fourth CERN Golden Hadron awards saw seven of the LHC's best suppliers receive recognition

CERN Multimedia

Maximilien Brice

2005-01-01

'The Golden Hadron awards are a symbol of our appreciation of not only the quality and timely delivery of components but also the collaborative and flexible way the firms have contributed to this very difficult project,' said Lyn Evans, head of the LHC project.

Higher Doses of (+)MK-801 (Dizocilpine) Induced Mortality and Procedural but Not Cognitive Deficits in Delayed Testing in the Active Place Avoidance With Reversal on the Carousel

Czech Academy of Sciences Publication Activity Database

Lobellová, Veronika; Brichtová, Eva; Petrásek, Tomáš; Valeš, Karel; Stuchlík, Aleš

2015-01-01

Roč. 64, č. 2 (2015), s. 269-275 ISSN 0862-8408 R&D Projects: GA MZd(CZ) NT13386 Institutional support: RVO:67985823 Keywords : Dizocilpine * (+)MK-801 * active place avoidance * Carousel * Long-Evans rats Subject RIV: FH - Neurology Impact factor: 1.643, year: 2015

Exploring the role of Environmental Quality and time Perspective in ...

African Journals Online (AJOL)

environmental quality as well as time perspective on academic performance within ... cognitive factors such as concentration, perception, memory and reason (Louw, Van Ede & ... (Reader's Digest, 1987) or the social or psychological conditions (Evans, .... The person who sees the consequences of his/her actions as being.

An Odyssey into the New Millennium: Rediscover 21st Century Business & Marketing Education. Proceedings of the Annual Atlantic Coast Business & Marketing Education Conference (18th, Raleigh, North Carolina, February 15-17, 2001).

Science.gov (United States)

Tucker, Sheila, Ed.

The following 13 papers on business and marketing education are included in this document: "Internet Marketing" (Herb Brown, Jerry Kandies); "Disk This . . . Paper Flow on the Go!" (Mary Evans, Wilbur Whitley); "Production and Evaluation of On-Line Tutorials" (Margie Gallagher, Evelyn Farrior, Jane Geissler);…

Quantitative geomorphology with geographical information systems (GIS) for evolving societies and science

Science.gov (United States)

Gomez, C.; Oguchi, T.; Evans, I. S.

2016-05-01

Based on the two sessions on spatial analysis, GIS and geostatistics convened by T. Oguchi, I. Evans and C. Gomez at the 2013 International Association of Geomorphology in Paris, the conveners have edited two special issues on the topic: volume 242 and the present one.

A NOVEL PNYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR DIMETHYLARSINIC ACID (DMA): THE LUNG AS A STORAGE COMPARTMENT

Science.gov (United States)

A NOVEL PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR DIMETHYLARSINIC ACID (DMA): THE LUNG AS A STORAGE COMPARTMENT. Evans, M.V., Hughes, M.F., and Kenyon, E.M. USEPA, ORD, NHEERL, RTP, NC 27711DMA is the major methylated metabolite of inorganic arsenic, a kno...

Õppiv organisatsioon ja juhtimise uus paradigma / Harry Roots

Index Scriptorium Estoniae

Roots, Harry, 1950-2010

2004-01-01

Juhtimise uus paradigma tähendab varasemaga võrreldes märgatavalt soodsama õpikeskkonna loomist. Nii nagu igapäevane juhtimispraktika kujundab organisatsioonis domineerivat kultuuritüüpi, samamoodi see ka kas soodustab või tõkestab õppiva organisatsiooni kujunemist, leiab autor. Tabelid. Skeemid

Recommendations for communication to enhance informed consent ...

African Journals Online (AJOL)

Recommendations for communication to enhance informed consent and enrolment at multilingual research sites. Claire Penn, Melanie Evans. Abstract. Language issues can affect HIV and AIDS research trial enrolment, but little is understood about variables in this process. Some evidence indicates barriers exist even ...

Sterilization of health care products - Radiation. Part 2: Establishing the sterilization dose

International Nuclear Information System (INIS)

2006-01-01

devised specifically for substantiation of 25 kGy, Method VD max, was put forward by Kowalski and Tallentire (1999) [14]. Subsequent evaluations involving computational techniques demonstrated that the underlying principles were soundly based (Kowalski, Aoshuang and Tallentire, 2000) [13] and field trials confirmed that Method VD max is effective in substantiating 25 kGy for a wide variety of medical devices manufactured and assembled in different ways (Kowalski et al., 2002) [16]. A standardized procedure for the use of VD max for substantiation of a sterilization dose of 25 kGy has been published in the AAMI Technical Information Report Sterilization of health care products -- Radiation sterilization -- Substantiation of 25 kGy as a sterilization dose - Method VD max (AAMI TIR27:2001) [5], a text on which the method described herein is largely based. Method VD max is founded on dose setting Method 1 and, as such, it possesses the high level of conservativeness characteristic of Method 1. In a similar manner to the dose setting methods, it involves performance of tests of sterility on product items that have received a dose of radiation lower than the sterilization dose. The outcomes of these tests are used to substantiate that 25 kGy achieves an SAL of 10 -6 . To link the use of VD max for the substantiation of a particular preselected sterilization dose, the numerical value of the latter, expressed in kGy, is included as a superscript to the VD max symbol. Thus, for substantiation of a sterilization dose of 25 kGy the method is designated VD max 25 . Method VD max 15 is based on the same principles as Method VD max 25 described above. The test procedure is the same as Method VD max 25 , but VD max 15 is limited to product with average bioburden ≤ 1,5. The outcomes of these tests are used to substantiate that 15 kGy achieves a sterility assurance level of 10 -6 . This part of ISO 11137 also describes methods that may be used to carry out sterilization dose audits in

A Study of University Efforts to Provide Students with the Ability to Comprehend and Apply Total Quality Principles in Their Fields of Study

Science.gov (United States)

1993-09-01

Geber , 1990:30-31). These steps are a formula to implement and measure quality in a service organization. While guidelines such as these apply to...1991. Evans, James R. and William M. Lindsay. The Management and Control of Quality. Minneapolis/St. Paul: West Publishing Company, 1993. Geber

77 FR 5481 - Notice of Request for Extension of Approval of an Information Collection; Special Need Requests...

Science.gov (United States)

2012-02-03

... Plant Protection Act AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of...: For information on special need requests under the Plant Protection Act, contact Ms. Lynn Evans...: Special Need Request Under the Plant Protection Act. OMB Number: 0579-0291. Type of Request: Extension of...

Kõik teed viivad pimedatel talveöödel kinodesse! / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2007-01-01

Pimedate Ööde 11. filmifestivali filmiprogrammidest "Päike tõuseb idast", Screen International", "Igapäevane põrgu", "Panoraam" "11 valitud teost", "Foorum". Soovitusi filmivaatamiseks annavad veel Tauno Maripuu ("Minu tädi postmodernistlik elu"), Kristi Eberhart ("Minu vend on ainus laps"), Rain Tolk ("Vaimud")

Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy.

Science.gov (United States)

Kaelen, Mendel; Giribaldi, Bruna; Raine, Jordan; Evans, Lisa; Timmermann, Christopher; Rodriguez, Natalie; Roseman, Leor; Feilding, Amanda; Nutt, David; Carhart-Harris, Robin

2018-05-01

The article The hidden therapist: evidence for a central role of music in psychedelic therapy, written by Mendel Kaelen, Bruna Giribaldi, Jordan Raine, Lisa Evans, Christopher Timmerman, Natalie Rodriguez, Leor Roseman, Amanda Feilding, David Nutt, Robin Carhart-Harris, was originally published electronically on the publisher's internet portal.

Effects of Syntactic Complexity, Semantic Reversibility, and Explicitness on Discourse Comprehension in Persons with Aphasia and in Healthy Controls

Science.gov (United States)

Levy, Joshua; Hoover, Elizabeth; Waters, Gloria; Kiran, Swathi; Caplan, David; Berardino, Alex; Sandberg, Chaleece

2012-01-01

Purpose: Prior studies of discourse comprehension have concluded that the deficits of persons with aphasia (PWA) in syntactically based comprehension of sentences in isolation are not predictive of deficits in comprehension of sentences in discourse (Brookshire & Nicholas, 1984; Caplan & Evans, 1990). However, these studies used semantically…

Disease: H00349 [KEGG MEDICUS

Lifescience Database Archive (English)

Full Text Available ealth 15:673-91 (2010) DOI:10.1111/j.1365-3156.2010.02521.x ... PMID:21412875 (drug) ... AUTHORS ... Evans JR, Solomon AW ... TITLE ... Antibi...otics for trachoma. ... JOURNAL ... Cochrane Database Syst Rev CD001860 (2011) DOI:10.1002/14651858.CD001860.pub3

Short communication

African Journals Online (AJOL)

raoul

2011-03-14

Mar 14, 2011 ... Zipporah Gatheru8, Patrick Wamae Maranga9, Alassane Dicko10, Adegoke Gbadegesin Falade11, Angeline Yvette Crescence Boula12, Stephanus. Benjamin Kuit13, Olumuyiwa O Odusanya14, Papa Salif Sow15, Nuruddin Lakhani16, Evans Mwila Mpabalwani17, Jean-Jacques Muyembe Tamfum18,.

Download this PDF file

African Journals Online (AJOL)

EliasN

economic development of the country and to improve the living standards of its ... enhancement of 'the role of the private sector' and foreign investment. ... incentives further include income tax exemption for expansion or upgrading, ...... transformation and development.90 Evans cites the East Asian NICs as examples.

Novel Functional Extended Solids at Extreme Conditions

Science.gov (United States)

2013-02-01

15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a...ray Evidences J. Chem. Phys. 134, 044519 (2011). 19. Magnus J. Lipp, Jae-Hyun Klepeis, Bruce Baer, Hyunchae Cynn, William J. Evans, Valentin Iota

Investigating the potential of Aucoumea klaineana Pierre sapwood ...

African Journals Online (AJOL)

vainqueuer

2016-11-16

Nov 16, 2016 ... African Journal of Biotechnology. Full Length Research Paper. Investigating the potential ... them to release neutral sugars for the production of cellulosic ethanol. Aucoumea klaineana Pierre. (Okoumé) wood ... feedstocks for ethanol production in the future. Evans. (2005) has explained that, being 50% of ...

The Director-General visits the ATLAS construction site at Point 1

CERN Multimedia

Patrice Loiez

1998-01-01

Photo 05 : Claude Guitton (left), Project Manager for the EDF/Knight Piesold joint venture responsible for design and site supervision for LHC civil engineering at Point 1 takes the Director-General Chris Llewellyn Smith and LHC Project Leader Lyn Evans on a tour of the site.

77 FR 69620 - Casmalia Disposal Site; Notice of Proposed CERCLA Administrative De Minimis Settlement

Science.gov (United States)

2012-11-20

... settlements. This settlement is intended to resolve the liabilities of 290 settling parties for the Casmalia... settlement requires these parties to pay over $2 million to EPA. Settling Parties: Parties that have elected...., Entenmann's/Orowheat, Eva Fkiaras, Evans Tank Lines, Exel Corp./Exel Microelectronics, Inc., Fabri Cote...

DEPRESSION OF THE PHOTIC AFTER DISCHARGE OF FLASH EVOKED POTENTIALS BY PHYSOSTIGMINE, CARBARYL AND PROPOXUR AND THE RELATIONSHIP TO INHIBITION OF BRAIN CHOLINESTERASE

Science.gov (United States)

The effects of N-methyl carbamate pesticides on the photic after discharge (PhAD) of flash evoked potentials (FEPs) and the relationship between inhibition of brain cholinesterase (ChE) activity and the PhAD were evaluated. FEPs were recorded in Long Evans rats treated with physo...

E-Professionalism for Early Care and Education Providers

Science.gov (United States)

Harte, Helene Arbouet

2011-01-01

Teachers of young children work hard to be professional and to be viewed by others as professionals. These efforts to maintain professionalism must include e-professionalism. E-professionalism involves behavior related to professional standards and ethics when using electronic communication (Evans & Gerwitz, 2008). Cellular telephones, social…

An Exploratory Study of Individual and Organizational Variable Interrelationships in Research and Development Organizations within Air Force Systems Command.

Science.gov (United States)

1986-09-01

31:493). Farace defines communication as "the exchange of symbols 6 that are commonly shared by the individuals involved, and which evoke 13 Ip...1981). r 9. Evans, C. George. Supervising R&D Personnel. New York: American Management Association, 1969. 10. Farace , Richard V. and others

U-N-F-O-R-G-E-T-T-A-B-L-E!

CERN Multimedia

2008-01-01

This is the word that best describes 10 September for all CERN personnel and surely also the outside world watching CERN through the eyes of the media. The unforgettable "3-2-1 BEAM!" of the LHC project leader, Lyn Evans, will stay in our memories forever.

Obesity-related changes in bone structural and material properties in hyperphagic OLETF rats and protection by voluntary wheel running

Science.gov (United States)

We conducted a study to examine how the development of obesity and the associated insulin resistance affect bone structural and material properties, and bone formation and resorption markers in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat model. This was a 36-week study of sedentary, hyperphag...

Trends in Female Authorships, Editorial Board Memberships, and Editorships in Educational Psychology Journals from 2003 to 2008

Science.gov (United States)

Fong, Carlton J.; Yoo, Julia H.; Jones, Sara J.; Torres, Laura G.; Decker, Mark Lowry

2009-01-01

Robinson, McKay, Katayama, and Fan ("Contemporary Educational Psychology," 23, 331-343, 1998) reported that women were underrepresented in terms of authorships, editorial board memberships, and editorships in the field of educational psychology based on membership trends. More recently, Evans, Hsieh, and Robinson ("Educational Psychology Review,"…

Southern Forests: a Journal of Forest Science - Vol 191 (2001)

African Journals Online (AJOL)

Valuing South Africa's savannas: methodological issues · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Ballance, CM Shackleton, SE Shackleton, B Geach, D Crookes, M De Wit, J Evans, G Von Maltitz, C Willis, S Kelatwang, J Havemann, 43-52 ...

USING IN VIVO GAS UPDATE STUDIES TO ESTIMATE METABOLIC RATE CONSTANTS FOR CCL CHEMICALS: 1,1-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE

Science.gov (United States)

USING IN VIVO GAS UPTAKE STUDIES TO ESTIMATE METABOLIC RATE CONSTANTS FOR CCL CHEMICALS: 1,1-DICHLOROPROPENE AND 2,2-DICHLOROPROPANE. Mitchell, C T, Evans, M V, Kenyon, E M. NHEERL, U.S. EPA, ORD, ETD, RTP, NC The Safe Drinking Water Act Amendments of 1996 required ...

77 FR 29967 - Notice of Intent To Terminate the Existing Draft Environmental Impact Statement and Prepare a New...

Science.gov (United States)

2012-05-21

... the request following the Ninth Circuit Court's decision in Anderson v. Evans, 371 F.3d 475, that the... to subsequently develop an informed decision; (2) ensure that NEPA reviews provide high quality environmental information via clear and concise documentation; and (3) ensure that the high quality...

Author Details

African Journals Online (AJOL)

Ascott-Evans, BH. Vol 13, No 1 (2008) - Articles Joint Consensus: Hormone therapy in postmenopausal osteoporosis: 2008. Abstract · Vol 14, No 2 (2009) - Articles A patient with multiple phaeochromocytomas and visual loss. Abstract PDF · Vol 17, No 2 (2012) - Articles Pulmonary hypertension and thyrotoxicosis

The Universities and the Challenge of Realism

Science.gov (United States)

Evans, Mary

2010-01-01

Universities are often enjoined to "get" with the "real world". In this article, Mary Evans gives an account of interpretations of literary realism in order to consider the "coercive realism" of the contemporary university. The prevailing assumptions that universities must contribute to the "real" world are…

Fluid resuscitation following a burn injury: implications of a mathematical model of microvascular exchange.

Science.gov (United States)

Bert, J; Gyenge, C; Bowen, B; Reed, R; Lund, T

1997-03-01

A validated mathematical model of microvascular exchange in thermally injured humans has been used to predict the consequences of different forms of resuscitation and potential modes of action of pharmaceuticals on the distribution and transport of fluid and macromolecules in the body. Specially, for 10 and/or 50 per cent burn surface area injuries, predictions are presented for no resuscitation, resuscitation with the Parkland formula (a high fluid and low protein formulation) and resuscitation with the Evans formula (a low fluid and high protein formulation). As expected, Parkland formula resuscitation leads to interstitial accumulation of excess fluid, while use of the Evans formula leads to interstitial accumulation of excessive amounts of proteins. The hypothetical effects of pharmaceuticals on the transport barrier properties of the microvascular barrier and on the highly negative tissue pressure generated postburn in the injured tissue were also investigated. Simulations predict a relatively greater amelioration of the acute postburn edema through modulation of the postburn tissue pressure effects.

Partnership in space the mid to late nineties

CERN Document Server

Evans, Ben

2014-01-01

This latest entry in the History of Human Space Exploration miniseries by Ben Evans continues with an in-depth look at the mid to late Nineties. Picking up where Tragedy and Triumph in Orbit: The Eighties and Early Nineties left off, the story commemorating the evolution of manned space exploration unfolds here in yet more detail. More than fifty years after Yuri Gagarin’s pioneering journey into space, Evans extends his comprehensive overview of how that momentous journey continued through the decades that followed.   Partnership in Space, the fifth book in the series, explores the final years in which the United States and the Soviet Union – which became the Commonwealth of Independent States in 1992 – pursued human space endeavors independently of each other.   The narrative follows the path taken by two old foes towards an unlikely and often controversial partnership. As the Shuttle program recovered from the loss of Challenger and pursued ever loftier goals, including the ambitious repair of the ...

LHC: seven golden suppliers

CERN Multimedia

2005-01-01

The fourth CERN Golden Hadron awards saw seven of the LHC's best suppliers receive recognition for the high quality of their work, compliance with delivery deadlines, flexibility and adaptability to the demanding working conditions of the project. The representatives of the seven companies which received awards during the Golden Hadron ceremony, standing with Lyn Evans, LHC Project Leader. 'The Golden Hadron awards are a symbol of our appreciation of not only the quality and timely delivery of components but also the collaborative and flexible way the firms have contributed to this very difficult project,' said Lyn Evans, head of the LHC project. The awards went to Kemppi-Kempower (Finland), Metso Powdermet (Finland), Transtechnik (Germany), Babcock Noell Nuclear (Germany), Iniziative Industriali (Italy), ZTS VVU Kosice (Slovakia), and Jehier (France). Babock Noell Nuclear (BNN) successfully produced one-third (416 cold dipole masses) of the LHC's superconducting dipole magnets, one of the most critical an...

The mechanism distinguishability problem in biochemical kinetics: the single-enzyme, single-substrate reaction as a case study.

Science.gov (United States)

Schnell, Santiago; Chappell, Michael J; Evans, Neil D; Roussel, Marc R

2006-01-01

A theoretical analysis of the distinguishability problem of two rival models of the single enzyme-single substrate reaction, the Michaelis-Menten and Henri mechanisms, is presented. We also outline a general approach for analysing the structural indistinguishability between two mechanisms. The approach involves constructing, if possible, a smooth mapping between the two candidate models. Evans et al. [N.D. Evans, M.J. Chappell, M.J. Chapman, K.R. Godfrey, Structural indistinguishability between uncontrolled (autonomous) nonlinear analytic systems, Automatica 40 (2004) 1947-1953] have shown that if, in addition, either of the mechanisms satisfies a particular criterion then such a transformation always exists when the models are indistinguishable from their experimentally observable outputs. The approach is applied to the single enzyme-single substrate reaction mechanism. In principle, mechanisms can be distinguished using this analysis, but we show that our ability to distinguish mechanistic models depends both on the precise measurements made, and on our knowledge of the system prior to performing the kinetics experiments.

India and CERN: a collaboration in good shape

CERN Multimedia

2002-01-01

The addenda were signed by the director of India's Centre for Advanced Technology, Dilip Bhawalkar, and LHC project leader, Lyn Evans. Back row, from left to right: P.J. Bryant, Ph. Lebrun, V.C. Sahni, M. Karmarkar, S. Bhave, G. Govindarajan. The director of India's Centre for Advanced Technology, Dilip Bhawalkar, and LHC project leader Lyn Evans have just signed the final addenda for the first Indian contribution to the LHC at a meeting of the Indian Department of Atomic Energy (DAE) - CERN joint committee. The main component of this contribution covers the superconducting corrector magnets for the accelerator's main dipoles and quadrupoles. During their visit, members of the DAE delegation visited the assembly laboratory where Indian engineers working at CERN under the CERN-India co-operation agreement are involved in the warm and cold magnet measurements of the LHC magnets. The Indian collaboration with CERN started in 1991, when India signed a co-operation Agreement with CERN with a view to participatin...

MANAGEMENT BOARD MEETING OF 30 SEPTEMBER 1999

CERN Multimedia

1999-01-01

For informationOutcome of the September meetings of the Scientific Policy Committee, Finance Committee and Committee of Council.The Management Board's September meeting was mainly devoted to a review of the recent meetings of the Scientific Policy Committee, Finance Committee and Committee of Council. The Director-General reported on the following highlights:LHC Status ReportStatus reports on the LHC machine presented by L. Evans, the LHC Project Leader, had been well received by the Scientific Policy Committee and Committee of Council, which had expressed satisfaction at the progress made. Informing them of an accident that had occurred during the testing of the first long LHC dipole as an illustration of problems encountered and successfully overcome, Dr Evans had explained that sparking in the 15-m dipole had resulted in significant external damage and an unprotected quench. After re-tuning, however, the magnet had been successfully re-powered to reach well above the nominal field at first quench, thus dem...

p-topological Cauchy completions

Directory of Open Access Journals (Sweden)

J. Wig

1999-01-01

Full Text Available The duality between “regular” and “topological” as convergence space properties extends in a natural way to the more general properties “p-regular” and “p-topological.” Since earlier papers have investigated regular, p-regular, and topological Cauchy completions, we hereby initiate a study of p-topological Cauchy completions. A p-topological Cauchy space has a p-topological completion if and only if it is “cushioned,” meaning that each equivalence class of nonconvergent Cauchy filters contains a smallest filter. For a Cauchy space allowing a p-topological completion, it is shown that a certain class of Reed completions preserve the p-topological property, including the Wyler and Kowalsky completions, which are, respectively, the finest and the coarsest p-topological completions. However, not all p-topological completions are Reed completions. Several extension theorems for p-topological completions are obtained. The most interesting of these states that any Cauchy-continuous map between Cauchy spaces allowing p-topological and p′-topological completions, respectively, can always be extended to a θ-continuous map between any p-topological completion of the first space and any p′-topological completion of the second.

Medium corrections to nucleon-nucleon interactions

International Nuclear Information System (INIS)

Dortmans, P.J.; Amos, K.

1990-01-01

The Bethe-Goldstone equations have been solved for both negative and positive energies to specify two nucleon G-matrices fully off of the energy shell. Medium correction effects of Pauli blocking and of the auxiliary potential are included in infinite matter systems characterized by fermi momenta in the range 0.5 fm -1 to 1.8 fm -1 . The Paris interaction is used as the starting potential in most calculations. Medium corrections are shown to be very significant over a large range of energies and densities. On the energy shell values of G-matrices vary markedly from those of free two nucleon (NN) t-matrices which have been solved by way of the Lippmann-Schwinger equation. Off of the energy shell, however, the free and medium corrected Kowalski-Noyes f-ratios rate are quite similar suggesting that a useful model of medium corrected G-matrices are appropriately scaled free NN t-matrices. The choice of auxiliary potential form is also shown to play a decisive role in the negative energy regime, especially when the saturation of nuclear matter is considered. 30 refs., 7 tabs., 7 figs

Effects of false feedback on affect, cognition, behavior, and postevent processing: the mediating role of self-focused attention.

Science.gov (United States)

Makkar, Steve R; Grisham, Jessica R

2013-03-01

Current social phobia models (e.g., Clark & Wells, 1995; Leary & Kowalski, 1995) postulate that socially anxious individuals negatively appraise their anxiety sensations (e.g., sweating, heart racing, blushing) as evidence of poor social performance, and thus fear these anxiety symptoms will be noticed and judged negatively by others. Consequently, they become self-focused and hypervigilant of these sensations and use them to judge how they appear to others. To test this model, high (N=41) and low (N=38) socially anxious participants were shown false physiological feedback regarding an increase or decrease in heart rate prior to and during an impromptu speech task. Relative to participants who observed a false heart rate decrease, those in the increase condition reported higher levels of negative affect, more negative performance appraisals, and more frequent negative ruminative thoughts, and these effects were mediated by an increase in self-focused attention. The unhelpful effects of the physiological feedback were not specific to high socially anxious participants. The results have implications for current cognitive models as well as the treatment of social phobia. Copyright © 2012. Published by Elsevier Ltd.

Analysis of selected reservoirs functioning in the Wielkopolska region

Directory of Open Access Journals (Sweden)

Mariusz Sojka

2017-12-01

Full Text Available The paper presents the problems related to the functioning of reservoirs in the Wielkopolska province and suggests their possible solutions. The reservoirs chosen as examples include typical dam constructions with a single water body (Jeziorsko, Rydzyna, two water body objects with separated preliminary part (Stare Miasto, Kowalskie, Radzyny and lateral constructions (Pakosław, Jutrosin. The reservoirs were built in period from 1970 to 2014. They differ in construction, functions and water management rules. Analysis of the main problems related to the reservoir functioning is aimed at finding ways of improving the construction of new reservoirs that would satisfy increasingly stringent environmental and legal restrictions and the methods of water management in the reservoirs. On the basis of a questionnaire filled in by the reservoir operators, the main problem is water quality. Especially the huge inflow of biogenic compounds causes blooms of algae and overgrowth with riparian vegetation. Some difficulties are also related to management of the reservoirs of multi-purpose operation. It is difficult to take into account the requirements of environmental flow maintenance, flood protection, water supply for agriculture and water use for tourism and recreation and hydropower generation, etc.

Security: Individuals and Leviathans

Science.gov (United States)

2013-05-20

involved named their action Operation Unified Protector. A principal author of the Right to Protect, adopted at the 2005 UN World Summit, Gareth Evans...Perspectives on and beyond Asia, ed Amitav Acharya and Barry Buzan (New York: Routledge, Taylor and Francis Group, 2010), 41-43. 127 Andrew Browne

Prevalence and morphometric studies on porcine cysticercosis in ...

African Journals Online (AJOL)

HP USER

Bourn D, Wint W, Blench R &Woolley E (1994). Nigerian Livestock Resources Survey, World. Animal Review, 78(1):49-58. Cox FEG (2002). History of human parasitology. Clinical Microbiology. Review. 15(4): 595-. 612. Garcia HH, Gonzalez AE, Evans CA &Gilman RH. (2003). Cysticercosis working group in Peru. Taenia.

75 FR 25885 - The Merit Systems Protection Board (MSPB) is Providing Notice of the Opportunity to File Amicus...

Science.gov (United States)

2010-05-10

... MERIT SYSTEMS PROTECTION BOARD The Merit Systems Protection Board (MSPB) is Providing Notice of the Opportunity to File Amicus Briefs in the Matter of Larry L. Evans v. Department of Veterans Affairs, MSPB Docket Number AT-3330-09-0953- I-1. AGENCY: Merit Systems Protection Board. ACTION: Notice...

78 FR 24157 - Foreign-Trade Zone 20-Suffolk, Virginia; Application for Reorganization and Expansion Under the...

Science.gov (United States)

2013-04-24

...)-- Kerma Medical Products, 215 Suburban Drive, Suffolk; Site 2 (10 acres)--Evans Distribution Systems, 324... Charles Sustainable Technologies Industrial Park, U.S. 13 on SR 1108, Cape Charles; Site 19 (323 acres... Production Road, Norfolk; Site 23 (101 acres)--Virginia Commerce Center, 351 Kenyon Road, Suffolk; Site 24...

The Coast Artillery Journal. Volume 83, Number 5, September-October 1940

Science.gov (United States)

1940-10-01

An army can use these methods as effectively as can American business. Cosmetic manufacturers know women will use a certain cosmetic , not only because...Department, sailing San Francisco, Oc- tober 8, 1940. )’lajor Fenton G. Epling, promoted Lieu- tenant Colonel, August 7, 1940. Major \\Villiam D. .Evans

"If They Can Say It They Can Write It": Inclusive Pedagogies for Senior Secondary Physical Education

Science.gov (United States)

Garrett, Robyne; Wrench, Alison

2016-01-01

Pedagogical practices are fundamental to teachers' work, and in the spaces of schooling impact significantly on students' success and achievement (Evans, J. 1986. "Physical Education, Sport and Schooling: Studies in the Sociology of Physical Education." London: Falmer Press.). This is especially the case for students from disadvantaged…

75 FR 51167 - Bank of Ruston, Ruston, Louisiana; Approval of Conversion Application

Science.gov (United States)

2010-08-18

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [AC-48 OTS Nos. 03912 and H4739] Bank of..., 2010, the Office of Thrift Supervision approved the application of Bank of Ruston, Ruston, Louisiana.... Dated: August 11, 2010. By the Office of Thrift Supervision. Sandra E. Evans, Federal Register Liaison...

75 FR 31511 - Oneida Financial Corp., Oneida, NY; Approval of Conversion Application

Science.gov (United States)

2010-06-03

... Office of Thrift Supervision approved the application of Oneida Financial, MHC and Oneida Savings Bank... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [AC-44: OTS No. H-4704] Oneida Financial... of Thrift Supervision. Sandra E. Evans, Federal Register Liaison. [FR Doc. 2010-13209 Filed 6-2-10; 8...

COMPARISON OF EEG CHANGES PRODUCED BY CARBARYL (CARBAMATE), PERMETHRIN (TYPE I PYRETHROID), AND DELTAMETHRIN (TYPE II PYRETHROID)

Science.gov (United States)

We have reported that treatment with carbaryl may alter Theta activity in the EEG (Lyke et al., Toxicologist, 108(S-1):441, 2009). In this study, we examined the ability to detect changes in EEG activity produced by pesticides with different modes of action. Long Evans rats were ...

153 - 158_Jacob_Antibacterial

African Journals Online (AJOL)

pc

A purple colour appearing at the interface indicates the presence of reducing sugar in the extract (Trease and Evans,. 2002). Test for alkaloids. Each extract (1 g) .... certain skin ailments. Terpenes help to counter stress and anxiety, improve mood, promote alertness and memory retention. For example, limonene, a major.

Over geschiedenis en antropologie : Een inleiding

NARCIS (Netherlands)

Kuiper, Yme; Borghuis, M. G.M.; Kuiper, Y.B.; Papousek, D.A.

1980-01-01

Already in the 1950s the British anthropologist Evans-Pritchard saw anthropology as being closer to history than to the natural sciences. Since the 1970s the rapprochement between history and anthropology became evident, especially in the UK, USA and France. How about the Netherlands? Here the works

Huanglongbing increases Diplodia Stem End Rot in Citrus sinensis

Science.gov (United States)

Huanglongbing (HLB), one of the most devastating diseases of citrus is caused by the a-Proteobacteria Candidatus Liberibacter. Diplodia natalensis Pole-Evans is a fungal pathogen which has been known to cause a postharvest stem-end rot of citrus, the pathogen infects citrus fruit under the calyx, an...

77 FR 23766 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978

Science.gov (United States)

2012-04-20

... 1978 (Pub. L. 95-541), as amended by the Antarctic Science, Tourism and Conservation Act of 1996, has... Evans to collect ground control points with highly precise GPS equipment. Their activity will include hiking within each area to readily-identify boulders, peaks, etc., gathering precise GPS coordinates of...

Digital wood craft

DEFF Research Database (Denmark)

Tamke, Martin; Ramsgaard Thomsen, Mette

2009-01-01

In 1995, Robin Evans points out in his book The Projective Cast how the development of techniques changed architecture and the space inhabited in times of Gothic and early Renaissance. We see a parallel phenomenon today, where the interplay of technology and tool gives shape to new design (Kolare...

The job satisfaction of principals of previously disadvantaged schools

African Journals Online (AJOL)

The aim of this study was to identify influences on the job satisfaction of previously disadvantaged school principals in North-West Province. Evans's theory of job satisfaction, morale and motivation was useful as a conceptual framework. A mixedmethods explanatory research design was important in discovering issues with ...

Acoustic Sensor Network Design for Position Estimation

Science.gov (United States)

2009-05-01

A., Pollock, S., Netter, B., and Low, B. S. 2005. Anisogamy, expenditure of reproductive effort, and the optimality of having two sexes. Operations...Research 53, 3, 560–567. Evans, M., Hastings, N., and Peacock , B. 2000. Statistical distributions. Ed. Wiley & Sons. New York. Feeney, L. and Nilsson, M

Exclusive Preference Develops Less Readily on Concurrent Ratio Schedules with Wheel-Running than with Sucrose Reinforcement

Science.gov (United States)

Belke, Terry W.

2010-01-01

Previous research suggested that allocation of responses on concurrent schedules of wheel-running reinforcement was less sensitive to schedule differences than typically observed with more conventional reinforcers. To assess this possibility, 16 female Long Evans rats were exposed to concurrent FR FR schedules of reinforcement and the schedule…

Factorised steady states and condensation transitions in ...

Indian Academy of Sciences (India)

As illustrated in figure 1 there exists an exact mapping from a ZRP to an asym .... internal structure, for example further degrees of freedom, but all this is integrated ..... A: Math. Gen. 32, L99 (1999). [10] M R Evans and R A Blythe, Physica A313, ...

Assessment of phthalate-induced changes in fetal rat testis gene expression using an rt-PCR array

Science.gov (United States)

Lambright, CS’, Sampson, H2, Furr, i1, Evans, N’, Hannas, B’, Gray, LE, Jr.’, VS Wilson1. 1USEPA, NHEERL, RTP, NC, 2USEPA, NHEERL, RTP, NC, ORISE Fellow. Phthalate esters (PE) such as diethyl hexyl phthalate (DEHP) produce reproductive malformations in male rodents by reduction o...

Asia-Pacific Research and Training Network on Trade (ARTNET ...

International Development Research Centre (IDRC) Digital Library (Canada)

During the first phase of support (102568), the Network produced a number of high quality trade policy studies, disseminated the results to policymakers and increased the capacity of research institutions - notably those in the least developed countries - to conduct trade policy ... Agent(e) responsable du CRDI. Due, Evan ...

Research

African Journals Online (AJOL)

believe that they provide adequate, timeous and sufficient quality feedback, despite evidence ... consultants with regard to the quality of feedback they provided to registrars employed at an ..... Veloski J, Boex J, Grasberger M, Evans A, Wolfson D. Systematic review of the literature on assessment, feedback and physicians' ...

Textile Tectonics

DEFF Research Database (Denmark)

Mossé, Aurélie

2008-01-01

of the discipline. Inspiring time gathering some of the most exciting architects of the moment, Lars Spuybroeck, Mark Burry, Evan Douglis, Michael Hensel and Cecil Balmond were invited to discuss their understanding of tectonics. Full text available at http://textilefutures.co.uk/exchange/bin/view/TextileFutures/TextileTectonics...

Njv Magazine 3 final

African Journals Online (AJOL)

En-Joy

protected by the calvaria. The calvarium is an important bony apparatus as it encase and protects the delicate brain tissues lying within it. The calvaria comprised the frontal, parietal, occipital, temporal and interparietal bones (Evans, 1993; Smuts and Bezuidenhout, 1987). Each bone shows a central trabecular network that.

THE PENALIZED OPTIMAL EXPERIMENTAL DESIGN: THE PRECISE ESTIMATION OF AN INTERACTION THRESHOLD IN A MIXTURE OF EIGHTEEN POLYHALOGENATED AROMATIC HYDROCARBONS.

Science.gov (United States)

Crofton et al. (EHP, 2005) conducted a study of 18 polyhalogenated aromatic hydrocarbons (PHAHs) on serum total thyroxine (T4). Young female Long-Evans rats were dosed with the 18 single agents or a fixed-ratio mixture, and serum total T4 was measured via radioimmunoassay. The i...

Proximate and Phytochemical Profile of Sansevieria liberica Gérôme ...

African Journals Online (AJOL)

Michael Horsfall

JASEM. Sansevieria liberica (family Agavaceae, Ruscaceae or. Dracaenaceae), is one of the bowstring hemp species. (Evans, 2005), with concave, short petioled leaves that are in part transversely banded with light and dark green, also linearly striated with whitish to light green and dark green striations (Reed, 1978). The.

Periodontitis contributes to aberrant metabolism in type 2 diabetes mellitus rats by stimulating the expression of adipokines.

Science.gov (United States)

Luo, S; Yang, X; Wang, D; Ni, J; Wu, J; Xu, Z; Xuan, D; Zhang, J

2016-08-01

Periodontitis has been associated with type 2 diabetes mellitus. We investigated the effects of local aberrant secretion of adipokines in diabetic rats on systemic metabolism. Otsuka Long-Evans Tokushima Fatty (OLETF) and non-diabetic Long-Evans Tokushima Otsuka rats were used as a diabetic model and associated control, respectively. Periodontitis was induced using a silk ligature for 36 wk. Rats were grouped into OLETF with (OP+) or without (OP-) periodontitis and Long-Evans Tokushima Otsuka with (LP+) or without (LP-) periodontitis. Alveolar bone resorption and destruction were evaluated by micro-computed tomography and hematoxylin and eosin staining. After 20 wk of periodontitis induction, lipids, insulin, interleukin-1, leptin and plasminogen activator inhibitor-1 were analyzed, and mRNA expressions of NF-κB, Mark8, TLR2 and -4, IKBKB and Nampt were evaluated by quantitative polymerase chain reaction in adipose tissue. After ligation, OLETF rats exhibited typical periodontitis lesions with the clinical features of type 2 diabetes mellitus. When compared with the OP(-) group, the area under curve of the oral glucose tolerance test and homeostatic model assessment-insulin resistance values were significantly higher in the OP(+) group. Micro-computed tomography showed that the OP(+) group had more bone resorption than the OP(-) group. When compared with the OP(-) group, the OP(+) group also exhibited higher total cholesterol (p 0.05) and higher expression of Nampt (p periodontitis can alter lipid profiles in affected rats, elevate adipose tissue expression of Nampt and affect the metabolism of adipose tissue through the NF-κB pathway to inflame diabetes. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effects of acidity and alkalinity on the stability of amidohydrolases in freshwater

Energy Technology Data Exchange (ETDEWEB)

Frankenberger, W.T. Jr.; Page, A.L.

1983-01-01

The influence of acidity and alkalinity on the enzymatic hydrolysis of amide-N in the aquatic system was investigated by determining the stability of L-asparaginase (EC (Enzyme Commission) 3.5.1.1), L-glutaminase (EC 3.5.1.2), and amidase (EC 3.5.1.4), and urease (EC 3.5.1.5) with respect to pH in three freshwater lakes. The water samples were first incubated at the indicated buffer pH (1-13) for 24 h; then each enzyme was assayed at its optimal pH (pH/sub opt/) under standardized conditions. L-Asparaginase retained essentially 100% of its activity within the pH range of 6-7 in Lake Evans and Lake Matthews, and 5-7 in Lake Perris. L-Glutaminase was active between pH 6 and 7 in the water samples surveyed. Amidase remained completely active at pH ranges of 4-8 in Lake Evans, 4-7 in Lake Matthews, and 5-8 in Lake Perris. Urease remained active over a broad pH range of 5-9 in Lake Evans, 5-8 in Lake Matthews, and 4-8 in Lake Perris. There was a progressive loss in enzyme activity below and above these pH ranges. The results suggest that the decline in aquatic amidohydrolase activities in relation to the pH-profile near their pH/sub opt/ was caused by a reversible reaction involving the ionization or deionization of functional groups of the active center of the protein, but under highly acidic or alkaline conditions (pH <4 to >9) the reduced activitiy appears to be due to irreversible inactivation of the enzyme.

Early Events in Populus Hybrid and Fagus sylvatica Leaves Exposed to Ozone

Directory of Open Access Journals (Sweden)

R. Desotgiu

2010-01-01

Full Text Available This paper aims to investigate early responses to ozone in leaves of Fagus sylvatica (beech and Populus maximowiczii x Populus berolinensis (poplar. The experimental setup consisted of four open-air (OA plots, four charcoal-filtered (CF open-top chambers (OTCs, and four nonfiltered (NF OTCs. Qualitative and quantitative analyses were carried out on nonsymptomatic (CF and symptomatic (NF and OA leaves of both species. Qualitative analyses were performed applying microscopic techniques: Evans blue staining for detection of cell viability, CeCl3 staining of transmission electron microscope (TEM samples to detect the accumulation of H2O2, and multispectral fluorescence microimaging and microspectrofluorometry to investigate the accumulation of fluorescent phenolic compounds in the walls of the damaged cells. Quantitative analyses consisted of the analysis of the chlorophyll a fluorescence transients (fast kinetics. The early responses to ozone were demonstrated by the Evans blue and CeCl3 staining techniques that provided evidence of plant responses in both species 1 month before foliar symptoms became visible. The fluorescence transients analysis, too, demonstrated the breakdown of the oxygen evolving system and the inactivation of the end receptors of electrons at a very early stage, both in poplar and in beech. The accumulation of phenolic compounds in the cell walls, on the other hand, was a species-specific response detected in poplar, but not in beech. Evans blue and CeCl3 staining, as well as the multispectral fluorescence microimaging and microspectrofluorometry, can be used to support the field diagnosis of ozone injury, whereas the fast kinetics of chlorophyll fluorescence provides evidence of early physiological responses.

IMIDACLOPRID PRODUCES MINIMAL CHANGES IN THE EEG OF LONG-EVANS RATS

Science.gov (United States)

We have reported that the non-stimulus driven EEG is differentially altered by deltamethrin or permethrin (Lyke and Herr, Toxicologist, 114(S-1) :265, 2010) as well as fipronil (Lyke and Herr, Toxicologist, 120(S-2) :290, 2011). In the current study, we examined the ability to de...

Antidiabetic Effects of Momordica charantia (Karela in Male long Evans Rat

Directory of Open Access Journals (Sweden)

Nurul Karim

2012-07-01

Full Text Available The hypoglycemic effect of Momordica charantia (Karela has been reported from many laboratories. To our knowledge the underlying biochemical mechanism of action of this important clinical effect has not been reported. During the course of investigation of this aspect of the herbal fruit, it was reported from our laboratory that ethanolic extract of Momordica charantia suppressed gluconeogenesis in normal and streptozotocin (STZ induced diabetic rats by depressing the hepatic gluconeogenic enzymes fructose-1,6-bisphosphatase and glucose-6-phosphatase. The herbal extract had also enhanced the activity of glucose-6-phosphate dehydrogenase, the rate limiting enzyme of hexose monophosphate shunt (a pathway for the oxidation of glucose.

A word from Lyn Evans:
A sprint to the finish

CERN Document Server

2008-01-01

Most people consider that the starting point for the LHC was a meeting organised by the European Committee for Future Accelerators in Lausanne in March 1984, even though quite a few of us at CERN had already begun work on the design in 1981. Since that time this truly unique machine has moved from a dream to a reality. With its ‘two in one’ magnet structure cooled by superfluid helium for operation at 1.9 K, the LHC is like no other particle collider. In a very real sense, the LHC is its own prototype. Other colliders have either consisted of two rings to accelerate and store two beams of particles, as in the Intersecting Storage Rings (ISR) here at CERN, or they have stored particles and their antiparticles travelling in opposite directions with a single ring, as we did with the Large Electron-Positron (LEP) collider. In addition, the LHC is the first accelerator in which the superconducting magnets have been cooled as low as 1...

The manuscript of Kartoteka (Card Index

Directory of Open Access Journals (Sweden)

Zbigniew Władysław Solski

2009-01-01

Full Text Available At the beginning of the 70s Tadeusz Różewicz presented the manuscript of Card Index to Professor Józef Kelera. It might have stayed a secret of friendship of the dramatist and the critic, however, Różewicz revealed the initials of his friend when in a commenatry to the play, he posed a question, whether there was a full stop after the last word in the manuscript or not? Posing this question, the author claimed the integrality of his masterpiece which was threatened by the widespread interpretations of Card Index as a play of a loose and dispersed structure. Appreciating the value of this question, I turned to Professor Kelera. This way I have had an access to the autograph of the play. In this manuscript has been preserved the play from before its final editing, which its author must surely have made during typing the text. Handwritten notes contain two unknown versions of the play with fragments which would not have been passed by the censors in the then Polish People’s Republic. In the reading of the manuscript the functions of the word and its graphic shape appeared of equal importance, so this version of Card Index can be recognised as a masterpiece of literature.

[The tragic doubt].

Science.gov (United States)

Musial, G

2001-01-01

Starting with two statements made by two great artists and witnesses of the XXth century - Joseph Brodsky and the Polish poet, Tadeusz Rozewicz - the author discusses the roots of our current moral crisis to which we ourselves bear witness: in the unchecked population explosion (Brodsky), and in the sinister legacy of World War II, the effects of which we witness on a daily basis (Rozewicz). The author recalls a third witness: Czeslaw Milosz, who wrote that the world's progress exhibits an inevitable tendency toward nihilism. In his discourse with the three statements mentioned, the author refers to certain XXth century intellectuals - Ortega y Gasset, Cardinal Joseph Ratzinger, Mircea Eliade, Herbert Read - who confirm and develop the thesis of man s spiritual fall and rejection of transcendence through technology. The author further illustrates his thesis with examples taken from the scientific research concerning IT, cloning, euthanasia, as well as from the world of the arts from the apocalyptic works of Hieronymous Bosch and Pieter Bruegel the Elder to the latest performers. He invokes a worldview which, by rejecting the metaphysics of man s birth, aging, and death, also rejects the judeo-christian taboo of the human body as a "dwelling place for the spirit" (porno festivals, exhibitions of human corpses by Prof. von Hagens in Germany).

[Distal fixation prosthesis for unstable intertrochanteric fractures in elderly patients: a mid-term follow-up study].

Science.gov (United States)

Zhang, Zhan-feng; Min, Ji-kang; Zhong, Jian-ming; Wang, Dan

2016-06-01

To explore mid-term follow up results of distal fixation prosthesis in treating unstable intertrochanteric fractures in elderly patients. From May 2008 to March 2014,58 elderly patients with unstable intertrochanteric were treated with distal fixation prosthesis, among them, there were 15 males and 43 females aged from 75 to 87 years old with an average of 83.2 years old. Fracture were classified according to Evans classification, 39 cases were type I c and 19 cases were type I d. Surgical risk was evaluated before operation, 9 patients were performed total hip arthroplasty and 49 patients were performed prosthetic replacement hip joint function of patients with different age period, Evans classificaton, prothesis type, fixation method were evaluated respectively by using Harris score. Fifty-six patients were followed up from 13 to 36 months with an average of 21.6 months. Harris score was 83.51 ± 6.40, 5 cases got excellent results, 38 cases good and 13 cases moderate. Harris score of patients aged from 75 to 80 years old was 88.64 ± 2.35, 81.64 ± 6.40 in patients aged more than 80 years old, and had significant differences between two groups; Harris score in patients with type Evans I c was 83.64 ± 6.53, and 83.11 ± 6.08 in type Evans I d, while there was no significant differences between two groups. There was no obvious meaning in Harris score between patients with tension band (83.63 ± 6.15) and without tension band (82.41 ± 6.57). There was no significant meaning in Harris score between patients with normal distal fixation prosthesis (83.34 ± 6.43) and femoral moment reconstruction distal fixation prosthesis (83.92 ± 6.51). There was 1 patient occurred hip joint dislocation on the operative side and re-dislocation after manual reduction, then received open reduction. Two patients occurred femoral osteolysis without clinical symptoms, and treated conservative treatment. Artificial joint replacement for unstable intertrochanteric fractures in elderly

Browse Title Index

African Journals Online (AJOL)

Items 101 - 108 of 108 ... Issue, Title. Vol 8, No 2 (2016), The status and challenges of clinical informatics development in South Africa, Abstract PDF. Abayomi Kehinde Owolabi, Thokozani Patrick Mhlongo, Neil Evans. Vol 4, No 1 (2012), The stuttering implementation of language policies in the South African education system ...

Temporal variations in the wind and wave climate at a location in the eastern Arabian Sea based on ERA-Interim reanalysis data.

Digital Repository Service at National Institute of Oceanography (India)

Shanas, P.R.; SanilKumar, V.

–597, 2011. Dube, S. K., Rao, A. D., Sinha, P. C., Murty, T. S., and Bahulayan, N.: Numerical modelling of storm surges in the Arabian Sea, Appl. Math. Model., 9, 289–294, 1997. Evan, A. T. and Camargo S. J.: A Climatology of Arabian Sea Cy- clonic Storms, J...

Extraocular myositis in a female puppy

African Journals Online (AJOL)

2015-04-27

Apr 27, 2015 ... ventral, ventromedial or medial strabismus have been reported (Allgoewer et al., 2000). The pathogenesis of this condition is not fully understood, but the one dominant histopathologic picture of the condition is that of mononuclear cellular infiltration (Carpenter et al.,. 1989; Ramsey et al., 1995; Evans et al., ...

Awards and Honours

CERN Multimedia

2009-01-01

Lyn Evans, LHC project leader and Welsh physicist, received an Honorary Doctorate from the University of Glamorgan on July 14. The University of Glamorgan is the second largest University in Wales with over 22,000 students. Visit the University website and read the full Press Release issued by the University.

The Perfect Mix: With Blended Professional Learning, Learners Choose Time, Place, Path, and Pace

Science.gov (United States)

Cieminski, Amie; Andrews, Deagan

2018-01-01

The Greeley-Evans School District in Colorado began moving toward innovation several years ago as district leaders searched for ways to improve student achievement, leverage technology, and stay within a very limited budget. In 2014, district leaders created a five-year blended learning implementation plan to increase student achievement that…

How Does School Mobility Impact Indicators of Academic Achievement for Highly Mobile Students?

Science.gov (United States)

Tanner-McBrien, Laura

2010-01-01

Children who are homeless or in foster care change schools more often than their non-mobile peers. The impact of school mobility increases their risk of academic failure (Evans, 1996; Ingersoll, Scamman, & Eckerling, 1989; Mao, 1997, Mehana & Reynolds, 2003; Reynolds & Wolf, 1999). Laws enforcing the right of students to remain in…

H.R. 4015, Jobs for Veterans Act. Hearing before the Subcommittee on Benefits of the Committee on Veterans' Affairs, House of Representatives. One Hundred Seventh Congress, Second Session (April 18, 2002).

Science.gov (United States)

Congress of the U.S., Washington, DC. House Committee on Veterans' Affairs.

This hearing provides the statements from the following individuals: Chairman Simpson; Hon. Silvestre Reyes; Hon. Ander Crenshaw; and Hon. Lane Evans (prepared statement of). This document also includes statements from over 10 wittinesses and contains an article, bill, chart, and statement submitted for the record relating to this hearing.…

THE BREEDING OF BEEF CATTLE IN soUTH AFRICA: PAST ...

African Journals Online (AJOL)

which I prefer, "breeding" is seen as the utilisation of total genetic variation ... was useful for preserving food and for the candle industry. (Evans and ... replaced by more productive types as mother stock while sires are .... Classification of cattle breeds used mainly for beef production in South Africa. Breeds ... maintenance.

Another Perspective: A Response to "Toward Convergence"

Science.gov (United States)

Regelski, Thomas A.

2013-01-01

This response by Thomas A. Regelski was solicited to complement the lead article in this issue, "Toward Convergence: Adapting Music Education to Contemporary Society and Participatory Culture" by Evan S. Tobias. The author notes that many interesting and vital questions and alternatives that are often studiously ignored, overlooked, or taken for…

Facts About Derechos - Very Damaging Windstorms

Science.gov (United States)

ABOUT DERECHOS Part of the NOAA-NWS-NCEP Storm Prediction Center web site Prepared by Stephen F . Corfidi, Jeffry S. Evans, and Robert H. Johns (with the help of many others) For feedback on "About Derechos," contact Stephen Corfidi Last updated May 15, 2018; see What's New for recent additions and

The last LHC dipole magnet is lowered

CERN Multimedia

Claudia Marcelloni

2007-01-01

A ceremony is held as the last of 1746 superconducting magnets is lowered into the 27-km circumference tunnel that houses the LHC. The LHC project leader, Lyn Evans, changes a banner reading ‘first magnet for the LHC’ to ‘last magnet for the LHC’ in his native Welsh.

Morphodynamics of the Kulsi River Basin in the northern front of ...

Indian Academy of Sciences (India)

65

... the Garo-Rajmahal depression (Evans 1964). The north to northeast ward counter. 1 clockwise movement of the Indian plate around the eastern Himalayan syntaxis (England and. 2. Bilham 2015) makes this plateau a geodynamically active block south of the Himalayan Frontal. 3. Thrust. The SP has witnessed the Great ...

Students' Sense of Responsibility in Event Planning: The Moral Aspect of Risk Management

Science.gov (United States)

Powellson, Tina Samuel

2010-01-01

Many scholars have asserted that college should contribute to the moral development of students, developing them into people who can think and act morally (Chickering, 1969; Evans, Forney, & Guido-DiBrito, 1998; Mathaisen, 2005). This responsibility applies not only to the classroom, but to the co-curricular experience as well. The…

77 FR 31216 - Changes in Flood Elevation Determinations

Science.gov (United States)

2012-05-25

..., Building B, 2nd Floor, Evans, GA 30809. Nevada: Clark (FEMA Docket No.: B- City of Henderson (11- October 6..., City of The Las Vegas Henderson, 240 Water Review-Journal. Street, Henderson, NV 89015. Clark (FEMA... 50 Journal. South, Willard, UT 84340. Virginia: Fauquier (FEMA Docket No.: B- Unincorporated areas...

Aerodynamic and Related Hydrodynamic Studies Using Water Facilities, Symposium of the Fluid Dynamics Panel Held in Monterey, California on 20-23 October 1986.

Science.gov (United States)

1987-06-01

dimensional simulation of the structure of this tip vortex can be carried out either on the Unigraphics UG-2 terminal or the Evans and Sutherland PS-300...fluid dynamics then to have close contact with John Stack (to whom we owe transonic developments then), Tony Ferri, Carl Kaplan, Adolf Busemann, Clint

Home Energy Saver

Science.gov (United States)

release announcing Home Energy Saver and a Q-and-A. The "About" page should tell you everything you need to know about using Home Energy Saver. If you have any questions, please email the project leader, Dr. Evan Mills. News Releases Microsoft Licenses Berkeley Lab's Home Energy Saver Code for Its

Images of the Great Depression: A Photographic Essay.

Science.gov (United States)

Stevens, Robert L.; Fogel, Jared A.

2001-01-01

Provides background information on the Farm Security Administration (FSA) and the photographic section of the FSA. Identifies six photographers and features three photographers (Walker Evans, Dorothea Lange, and Ben Shahn) who were recruited to document farm conditions. Discusses using FSA photos in the classroom and provides lesson plans to help…

African Journal of Marine Science - Vol 38, No 3 (2016)

African Journals Online (AJOL)

Protection of marine birds and turtles at St Brandon's Rock, Indian Ocean, requires conservation of the entire atoll · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. SW Evans, N Cole, H Kylin, NS Choong Kwet Yive, V Tatayah, J Merven, H Bouwman, 317-327.

Winds of Change: How Black Holes May Shape Galaxies

Science.gov (United States)

2010-03-01

New observations from NASA's Chandra X-ray Observatory provide evidence for powerful winds blowing away from the vicinity of a supermassive black hole in a nearby galaxy. This discovery indicates that "average" supermassive black holes may play an important role in the evolution of the galaxies in which they reside. For years, astronomers have known that a supermassive black hole grows in parallel with its host galaxy. And, it has long been suspected that material blown away from a black hole - as opposed to the fraction of material that falls into it -- alters the evolution of its host galaxy. A key question is whether such "black hole blowback" typically delivers enough power to have a significant impact. Powerful relativistic jets shot away from the biggest supermassive black holes in large, central galaxies in clusters like Perseus are seen to shape their host galaxies, but these are rare. What about less powerful, less focused galaxy-scale winds that should be much more common? "We're more interested here in seeing what an "average"-sized supermassive black hole can do to its galaxy, not the few, really big ones in the biggest galaxies," said Dan Evans of the Massachusetts Institute of Technology who presented these results at the High Energy Astrophysics Division of the American Astronomical Society meeting in Kona, Hawaii. Evans and his colleagues used Chandra for five days to observe NGC 1068, one of the nearest and brightest galaxies containing a rapidly growing supermassive black hole. This black hole is only about twice as massive as the one in the center of our Galaxy, which is considered to be a rather ordinary size. The X-ray images and spectra obtained using Chandra's High Energy Transmission Grating Spectrometer (HETGS) showed that a strong wind is being driven away from the center of NGC 1068 at a rate of about a million miles per hour. This wind is likely generated as surrounding gas is accelerated and heated as it swirls toward the black hole. A

Performance and Carcass Characteristics of Broiler Finisher Birds ...

African Journals Online (AJOL)

Sixty (60) 4 weeks old Anak broiler strain were subjected to 28 days feeding trial at the Poultry Unit of the Teaching and Research Farm, Evan Enwerem, Owerri, Nigeria, to determine the dietary effect of pineapple wine sediment (PWSM) on their performance and carcass characteristics. The birds were divided into four ...

Particularity and Reflexivity in the Intentional Content of Perception

Directory of Open Access Journals (Sweden)

Olga FERNÁNDEZ PRAT

2010-01-01

Full Text Available A significant part of perception is characterized by awareness of particular objects. Two ways of making precise this intuition have been proposed (Searle vs. Evans, Campbell and others. The dispute’s argumentative context is reconstructed and a proposal is advanced that may be regarded as a compromise between the contenders.

Solid State Quantum Computer in Silicon

Science.gov (United States)

2008-09-30

Zac Evans Martin Fuechsle Virginia Gill Toby Hopf Lenneke Jong Gajendran Kandasamy Wee Han Lim Graeme Lowe Melissa Makin Mladen Mitic Dane McCamey...Hudson 0.50 Linda Macks 0.50 Andrea Morello 1.00 Thilo Reusch 1.00 Frank Ruess 0.00 Giordano Scappucci 0.00 Laurens Willems van Beveren 0.60

Sewing Seams of Stories: Becoming a Teacher during the First World War

Science.gov (United States)

Sinner, Anita

2006-01-01

In this article the author shares a partial biography of Elizabeth Evans, who became a domestic science teacher in Britain during the First World War. This story begins with a small collection of artefacts--professional letters and personal photographs--which infuse our understanding of teaching and learning and Elizabeth's everyday life nearly a…

Vaesed tööloomad / Gert D. Hankewitz

Index Scriptorium Estoniae

Hankewitz, Gert D.

2008-01-01

Riikides, kus palgad ja elatustase on madalamad, tehakse rohkem ületunde, samas kui jõukates riikides on töötundide arv väiksem. Vt. samas: Neljapäevane töönädal ei tasunud ära. Diagramm: Reaalselt töötatud tundide arv nädalas riikide kaupa

NUDTSNA at TREC 2015 Microblog Track: A Live Retrieval System Framework for Social Network based on Semantic Expansion and Quality Model

Science.gov (United States)

2015-11-20

github.com/shuyo/ldig in a tweet. A tweet is structured as JSON format, it is convenient to get social attributes we need, such as the user who post...110. [6] K. Bollacker, C. Evans, P. Paritosh, T. Sturge, and J. Taylor, “Free- base: a collaboratively created graph database for structuring human

Touring the Campus Library from the World Wide Web.

Science.gov (United States)

Mosley, Pixey Anne; Xiao, Daniel

1996-01-01

The philosophy, design, implementation and evaluation of a World Wide Web-accessible Virtual Library Tour of Texas A & M University's Evans Library is presented. Its design combined technical computer issues and library instruction expertise. The tour can be used to simulate a typical walking tour through the library or heading directly to a…

Acylation, Diastereoselective Alkylation, and Cleavage of an Oxazolidinone Chiral Auxiliary: A Multistep Asymmetric Synthesis Experiment for Advanced Undergraduates

Science.gov (United States)

Smith, Thomas E.; Richardson, David P.; Truran, George A.; Belecki, Katherine; Onishi, Megumi

2008-01-01

An introduction to the concepts and experimental techniques of diastereoselective synthesis using a chiral auxiliary is described. The 4-benzyl-2-oxazolidinone chiral auxiliary developed by Evans is acylated with propionic anhydride under mild conditions using DMAP as an acyl transfer catalyst. Deprotonation with NaN(TMS)[subscript 2] at -78…

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (83rd, Phoenix, Arizona, August 9-12, 2000). Magazine Division.

Science.gov (United States)

Association for Education in Journalism and Mass Communication.

The Magazine Division section of the proceedings contains the following seven papers: "Farm Magazine Advertisers Turn Up the Heat: An Analysis of Ethical Pressures Faced by Farm Magazine Writers" (Stephen A. Banning and James Evans); "Framing a War: Photographic Coverage of the Kosovo War in Newsweek, Time, and U.S. News & World…

The Shaped Charge Concept. Part 2. The History of Shaped Charges

Science.gov (United States)

1990-09-01

research of Evans. Ubbel•ode. LAmurd-Jones, Devonihire, and An&ew. 1hW U.K. Mufied cadmium liners (which probably produce molten jets) msd steel liners...34 Mathematical Jet Theory of Lined Hollow Charges." BRL Report No. 370, U.S. Army Ballistic Research Laboratory. Aberdeen Proving Ground, MD, 18 June

as a Novel Chiral Ligand for Catalysis of the Asymmetric Diels-Al

African Journals Online (AJOL)

NJD

2008-11-25

Nov 25, 2008 ... P.I. Arvidsson, T. Govender, H.G. Kruger, G.E.M. Maguire and T. Naicker,. 60 .... Ni(ClO4)2. 120. 60 ..... 4 G. Desimoni, G. Faita and K.A. Jorgensen, Chem. ... 27 D.A. Evans, S.J. Miller, T. Lectka and P. von Matt, J. Am. Chem.

Staying Ahead of Childhood Diseases (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

2014-08-28

Many childhood diseases that used to cause epidemics in the United States are now rare thanks to vaccinations. In this podcast, Dr. Laurie Elam-Evans discusses the importance of keeping children up-to-date on recommended vaccinations.  Created: 8/28/2014 by MMWR.   Date Released: 8/28/2014.

A petition to Mr Peel: Gideon Mantell and the trial of Hannah Russell.

Science.gov (United States)

Flanagan, R J; Watson, K D

2009-07-01

In the summer of 1826, Hannah Russell was tried for petty treason, viz. the murder of her husband, Benjamin Russell, by poisoning. Their lodger, Daniel Leney, was indicted as her accomplice. The exact circumstances surrounding the death were unclear but Hannah was known to have purchased white arsenic (arsenious oxide). A local surgeon, Thomas Evans, supported at the post-mortem examination by two further surgeons, not only reported severe corrosion of the gastrointestinal tract, but also the recovery of nearly an eighth of an ounce of arsenic from the victim's stomach. Both accused were convicted and sentenced to death. Leney was executed, but Hannah Russell was respited because the trial judge, Sir Robert Graham, had doubts as to a direction he had given to the jury. The surgeon and paleontologist Gideon Mantell took up her case, stressing that death from arsenic could not have taken place as quickly as was alleged and maintaining that the chemical evidence of arsenic poisoning was inconclusive. He gained the support of some eminent chemists and physicians. Subsequently, forensic toxicologists [Sir] Robert Christison and Alfred Swaine Taylor pointed out that Mantell's arguments as to the possible time to death in arsenic poisoning were quite wrong. Moreover, Evans gave details of the analyses he and his colleagues had undertaken to Christison, who pronounced the findings sound, as indeed did Mantell after Evans and his colleagues published details of their investigations in the Sussex Advertiser. Papers in The National Archives show that Hannah was pardoned for the offence for which she was indicted, leaving it open to prefer a lesser charge. That this was never done may have been due to Mantell's campaign, at least in part, but the pardon she did receive was due to the concern of the trial judge as to the implications of the evidence presented at trial.

Strain-dependent sex differences in the effects of alcohol on cocaine-induced taste aversions.

Science.gov (United States)

Jones, Jermaine D; Busse, Gregory D; Riley, Anthony L

2006-04-01

Research using the conditioned taste aversion procedure has reported that a cocaine/alcohol combination induces a significantly stronger taste aversion than either cocaine or alcohol alone. These findings suggest that the co-administration of alcohol intensifies the aversive effects of cocaine. Although the behavioral interaction of cocaine and alcohol is well established, little is known about how the effects of this drug combination might be modulated by a variety of subject variables. The current investigation addressed this by assessing if the ability of alcohol to potentiate cocaine-induced taste aversions is dependent upon the strain and/or sex of the subject. In this series of studies, male and female rats of Long-Evans (Experiment 1) and Sprague-Dawley (Experiment 2) descent were given limited access to a novel saccharin solution to drink and were then injected with either vehicle, cocaine (20 mg/kg), alcohol (0.56 g/kg) or the alcohol/cocaine combination. This procedure was repeated every fourth day for a total of four conditioning trials. All subjects were then compared on an Aversion Test that followed the fourth conditioning cycle. In three of the groups tested (male Long-Evans; male and female Sprague-Dawley), cocaine induced a significant taste aversion that was unaffected by the co-administration of alcohol. However, in female Long-Evans subjects, the addition of alcohol significantly strengthened the avoidance of the saccharin solution. Although the effects of alcohol on cocaine-induced taste aversions are dependent upon an interaction of sex and strain, the basis for this SexxStrain interaction is not known. That such an interaction is evident suggests that attention to such factors in assessing the effects of drug combinations is important to understanding the likelihood of the use and abuse of such drugs.

The lazaroid U74389G protects normal brain from stereotactic radiosurgery-induced radiation injury

International Nuclear Information System (INIS)

Buatti, John M.; Friedman, William A.; Theele, Daniel P.; Bova, Francis J.; Mendenhall, William M.

1996-01-01

Purpose: To test an established model of stereotactic radiosurgery-induced radiation injury with pretreatments of either methylprednisolone or the lazaroid U74389G. Methods and Materials: Nine cats received stereotactic radiosurgery with a linear accelerator using an animal radiosurgery device. Each received a dose of 125.0 Gy prescribed to the 84% isodose shell to the anterior limb of the right internal capsule. One animal received no pretreatment, two received citrate vehicle, three received 30 mg/kg of methylprednisolone, and three received 5 mg/kg of U74389G. After irradiation, the animals had frequent neurologic examinations, and neurologic deficits developed in all of them. Six months after the radiation treatment, the animals were anesthetized, and had gadolinium-enhanced magnetic resonance (MR) scans, followed by Evans blue dye perfusion, euthanasia, and brain fixation. Results: Magnetic resonance scans revealed a decrease in the size of the lesions from a mean volume of 0.45 ± 0.06 cm 3 in the control, vehicle-treated, and methylprednisolone-treated animals to 0.22 ± 0.14 cm 3 in the U74389G-treated group. The scans also suggested the absence of necrosis and ventricular dilatation in the lazaroid-treated group. Gross pathology revealed that lesions produced in the untreated, vehicle-treated, and methylprednisolone-treated cats were similar and were characterized by a peripheral zone of Evans blue dye staining with a central zone of a mature coagulative necrosis and focal hemorrhage. However, in the U74389G-treated animals, the lesions were found to have an area of Evans blue dye staining, but lacked discrete areas of necrosis and hemorrhage. Conclusion: These results suggest that the lazaroid U74389G protects the normal brain from radiation injury produced by stereotactic radiosurgery

The influence of aging on the number of neurons and levels of non-phosporylated neurofilament proteins in the central auditory system of rats

Directory of Open Access Journals (Sweden)

Jana eBurianová

2015-03-01

Full Text Available In the present study, an unbiased stereological method was used to determine the number of all neurons in Nissl stained sections of the inferior colliculus (IC, medial geniculate body (MGB and auditory cortex (AC in rats (strains Long Evans and Fischer 344 and their changes with aging. In addition, using the optical fractionator and western blot technique, we also evaluated the number of SMI-32-immunoreactive(-ir neurons and levels of non-phosphorylated neurofilament proteins in the IC, MGB, AC, and visual cortex (VC of young and old rats of the two strains. The SMI-32 positive neuronal population comprises about 10% of all neurons in the rat IC, MGB and AC and represents a prevalent population of large neurons with highly myelinated and projecting processes. In both Long Evans and Fischer 344 rats, the total number of neurons in the IC was roughly similar to that in the AC. With aging, we found a rather mild and statistically non-significant decline in the total number of neurons in all three analyzed auditory regions in both rat strains. In contrast to this, the absolute number of SMI-32-ir neurons in both Long Evans and Fischer 344 rats significantly decreased with aging in all the examined structures. The western blot technique also revealed a significant age-related decline in the levels of non-phosphorylated neurofilaments in the auditory brain structures, 30-35%. Our results demonstrate that presbycusis in rats is not likely to be primarily associated with changes in the total number of neurons. On the other hand, the pronounced age-related decline in the number of neurons containing non-phosphorylated neurofilaments as well as their protein levels in the central auditory system may contribute to age-related deterioration of hearing function.

New Editor-in-Chief for Journal of Physics A: Mathematical and Theoretical

Science.gov (United States)

Gillan, Rebecca

2014-04-01

We are delighted to announce that Professor Martin Evans of University of Edinburgh has been appointed as the new Editor-in-Chief of Journal of Physics A: Mathematical and Theoretical. Martin Evans has been Editor of the Statistical Physics section of the journal since 2009. Prior to this, he served as a Board Member for the journal. His areas of research include statistical mechanics of nonequilibrium systems, phase transitions and scaling regimes in nonequilibrium statistical physics, glassy dynamics, phase transitions and ordering in driven diffusive systems, mass transport models, condensation models, zero range processes and exclusion processes. We very much look forward to working with Martin to continue to improve the journal's quality and interest to the readership. We would like to thank our outgoing Editor-in-Chief, Professor Murray Batchelor. Murray has worked hard and provided excellent guidance in improving the quality of the journal and the service that the journal provides to authors, referees and readers. During the last five years, we have raised the quality threshold for acceptance in the journal and currently reject over 70% of submissions. As a result, papers published in Journal of Physics A: Mathematical and Theoretical are amongst the best in the field. We have also maintained and improved on our excellent receipt-to-first-decision times, which now average under 40 days for papers. With the help of Martin Evans and our distinguished Editorial Board, we will be working to further improve the quality of the journal whilst continuing to offer excellent services to our readers, authors and referees. We hope that you benefit from reading the journal. If you have any comments or questions, please do not hesitate to contact us at jphysa@iop.org. Rebecca Gillan Publisher

Barrier effect of Esoxx® on esophageal mucosal damage: experimental study on ex-vivo swine model

Directory of Open Access Journals (Sweden)

Di Simone MP

2012-06-01

Full Text Available Massimo P Di Simone,1 Fabio Baldi,2,3 Valentina Vasina,4 Fabrizio Scorrano,5 Maria Laura Bacci,5 Antonella Ferrieri,6 Gilberto Poggioli11Department of General Surgery and Transplants, 2Centre for the Study and Therapy of the Esophageal Diseases, 3GVM Care and Research, MCH Cotignola (RA, 4Department of Pharmacology, Alma Mater Studiorum, University of Bologna, Bologna, 5Department of Veterinary Medical Science – DMSVET – University of Bologna, Bologna, 6Clinical Research Department, Alfa Wassermann Spa, Bologna, ItalyAbstract: The aim of the present study was to assess the potential barrier effect of Esoxx®, a new nonprescription medication under development for the relief of gastroesophageal reflux symptoms. Esoxx is based on a mixture of hyaluronic acid and chondroitin sulfate in a bioadhesive suspension of Lutrol® F 127 polymer (poloxamer 407 which facilitates the product adhesion on the esophageal mucosa. The mucosal damage was induced by 15 to 90 minutes of perfusion with an acidic solution (HCl, pH 1.47 with or without pepsin (2000 U/mL, acidified to pH 2; Sigma-Aldrich. Mucosal esophageal specimens were histologically evaluated and Evans blue dye solution was used to assess the permeability of the swine mucosa after the chemical injury. The results show that: (1 esophageal mucosal damage is related to the perfusion time and to the presence of pepsin, (2 mucosal damage is associated with an increased permeability, documented by an evident Evans blue staining, (3 perfusion with Esoxx is able to reduce the permeability of the injured mucosa, even after saline washing of the swine esophagus. These preliminary results support further clinical studies of Esoxx in the topical treatment of gastroesophageal reflux symptoms.Keywords: bioadhesion, hyaluronic acid, Evans blue dye, animal model, esophagus, reflux esophagitis

A novel model of IgE-mediated passive pulmonary anaphylaxis in rats.

Directory of Open Access Journals (Sweden)

Eva Wex

Full Text Available Mast cells are central effector cells in allergic asthma and are augmented in the airways of asthma patients. Attenuating mast cell degranulation and with it the early asthmatic response is an important intervention point to inhibit bronchoconstriction, plasma exudation and tissue oedema formation. To validate the efficacy of novel pharmacological interventions, appropriate and practicable in vivo models reflecting mast cell-dependent mechanisms in the lung, are missing. Thus, we developed a novel model of passive pulmonary anaphylaxis in rats. Rats were passively sensitized by concurrent intratracheal and intradermal (ear application of an anti-DNP IgE antibody. Intravenous application of the antigen, DNP-BSA in combination with Evans blue dye, led to mast cell degranulation in both tissues. Quantification of mast cell degranulation in the lung was determined by (1 mediator release into bronchoalveolar lavage, (2 extravasation of Evans blue dye into tracheal and bronchial lung tissue and (3 invasive measurement of antigen-induced bronchoconstriction. Quantification of mast cell degranulation in the ear was determined by extravasation of Evans blue dye into ear tissue. We pharmacologically validated our model using the SYK inhibitor Fostamatinib, the H1-receptor antagonist Desloratadine, the mast cell stabilizer disodium cromoglycate (DSCG and the β2-adrenergic receptor agonist Formoterol. Fostamatinib was equally efficacious in lung and ear. Desloratadine effectively inhibited bronchoconstriction and ear vascular leakage, but was less effective against pulmonary vascular leakage, perhaps reflecting the differing roles for histamine receptor sub-types. DSCG attenuated both vascular leakage in the lung and bronchoconstriction, but with a very short duration of action. As an inhaled approach, Formoterol was more effective in the lung than in the ear. This model of passive pulmonary anaphylaxis provides a tissue relevant readout of early mast cell

Effecting Student Learning for Historical Understanding

Science.gov (United States)

Lee, Gorman

2014-01-01

While there have been recent efforts to improve the overall public education system in the United States, American students continue to graduate from U.S. public high schools with limited knowledge of U.S. history (Ravitch, 1988; Evans, 2004; Ross, 2006; St. Jarre, 2008; Dillon, 2011). This qualitative case study investigated how high school…

COP 18 CARIAA Program presentation

International Development Research Centre (IDRC) Digital Library (Canada)

Blane Harvey

knowledge. Promote research uptake. Strengthen adaptation expertise. Our overarching aim: To develop robust evidence on how to increase the resilience of ... www.idrc.ca/cariaa. • cariaa@idrc.ca. Speak with us. • Isabelle Proulx. • Evans Kituyi. • Michele Leone. • K.S. Murali. • Blane Harvey. • Hayley Price. • Ken De ...

Afrikaans youth series books: exhibition of societal change | Snyman ...

African Journals Online (AJOL)

This article reports research on the history of the Afrikaans youth series book in the twentieth century. The polysystem theory of Evan-Zohar was taken as a theoretical basis for this study. An analysis of the publication history, as well as the content and settings of the researched series books for Afrikaans children, indicate ...

Repression of Cell Proliferation and Androgen Receptor Activity in Prostate Cancer Cells by 2'-Hydroxyflavanone

OpenAIRE

大筆, 光夫; Ofude, Mitsuo

2014-01-01

博士論文要旨Abstract 以下に掲載：Anticancer Research 33(10) pp.4453-4461 2013. The International Institute of Anticancer Research. 共著者：MITSUO OFUDE, ATSUSHI MIZOKAMI, MISAKO KUMAKI, KOUJI IZUMI, HIROYUKI KONAKA, YOSHIFUMI KADONO, YASUHIDE KITAGAWA, MINKYOUNG SHIN, JIAN ZHANG, EVAN T. KELLER, MIKIO NAMIKI 　

Fulltext PDF

Indian Academy of Sciences (India)

client1

Salt Lake City, UT, USA. Sir Martin J Evans – Cardiff University, Cardiff, United Kingdom. Oliver Smithies – University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Peace. “for their efforts to build up and disseminate greater knowledge about man-made climate change, and to lay the foundations for the measures ...

Shock and Vibration Bulletin No. 9

Science.gov (United States)

1948-04-14

Ann Arbor Attn: Prof. J. Ormondroyd (1) Stanford University, Stanford Attn: Prof. Lydik Jacqbsen, Dept. of Engineering (I) University of Illinois...J. L. 3mu C. J. Nelson D. L. Marlowe Bureau of Ordnance NavaI Oru6imnc Teot Station D. F. Anderson, Jr. Oscar D. Terrell B. C. Belyea L. R. Evans

Media and Attention, Cognition, and School Achievement

Science.gov (United States)

Schmidt, Marie Evans; Vandewater, Elizabeth A.

2008-01-01

Marie Evans Schmidt and Elizabeth Vandewater review research on links between various types of electronic media and the cognitive skills of school-aged children and adolescents. One central finding of studies to date, they say, is that the content delivered by electronic media is far more influential than the media themselves. Most studies, they…

A poor choice / Tõnu Naelapea

Index Scriptorium Estoniae

Naelapea, Tõnu, 1962-

2008-01-01

Järelkajad ja kommentaarid 1.-3. aprillini toimunud NATO 20. tippkohtumisele Bukarestis. Lääne hoiakutest suhetes Hiinaga. President Toomas Hendrik Ilves osales Bukarestis German Marshall Fund'i konverentsi "The Bucharest Conference" paneelis, kus põhiteemaks oli NATO lepingu 5. artikli tänapäevane roll. Blogipidaja Sameer Lalwani kommentaarist Eesti riigipea esinemisele

Multilevel Analysis of Student Civics Knowledge Scores

Science.gov (United States)

Gregory, Chris; Miyazaki, Yasuo

2018-01-01

Compositional effects of scholarly culture classroom/school climate on civic knowledge scores of 9th graders in the United States were examined using the International Association for the Evaluation of Educational Achievement (IEA) 1999 Civic Education Study data. Following Evans et al. (2010, 2014), we conceived that the number of books at home,…

Extraction Methodological Contributions Toward Ultra-Performance Liquid ChromatographyTime-of-Flight Mass Spectrometry: Quantification of Free GB from Various Food Matrices

Science.gov (United States)

2016-02-01

J.R.; Stubbs, S.J.; Read, R.W.; Evans, R.A.; Thomas , J.D.; Blake, T.A.; Johnson, R.C. Simultaneous Measurement of Tabun, Sarin, Soman, Cyclosarin, VR...Pesticide Residues in Food? J. Chromatogr. A 2000, 868, 51–61. 19. Schenck, F.J.; Podhorniak, L.V.; Hobbs , J.; Casanova, J.; Donoghue, D. Liquid

When Can We Say "If"?

Science.gov (United States)

Evans, Jonathan St. B. T.; Neilens, Helen; Handley, Simon J.; Over, David E.

2008-01-01

In this study, we focus on the conditions which permit people to assert a conditional statement of the form "if p then q" with conversational relevance. In a broadly decision-theoretic approach, also drawing on hypothetical thinking theory [Evans, J. St. B. T. (2007). "Hypothetical thinking: Dual processes in reasoning and judgement". Hove, UK:…

Consequences of diverse use of nitrogen sources on grain yield ...

African Journals Online (AJOL)

Muhammad Waseem

2012-08-28

Aug 28, 2012 ... sources on grain yield, grain quality and growth attributes of hybrid maize (Zea mays L.) at the. Agronomic Research Area, University ...... rate were found in 2009. Evans et al. (2003) also noted similar interactive effects of hybrid and N sources in maize. In year 2008, contrasts comparison (Table 4) between ...

Experimental real-time multi-model ensemble (MME) prediction of ...

Indian Academy of Sciences (India)

calibration (training) has to be of good quality. Otherwise, it might degrade the MME results. Early works by ... ECMWF ensemble data (Evans et al 2000), and they showed the superiority of the multi-model system over the ..... eral idea of the quality of rainfall forecasts in terms of error statistics for monsoon for the member.

The extent of groundwater use for domestic and irrigation activities ...

African Journals Online (AJOL)

AKMENSAH

2015-06-04

Jun 4, 2015 ... Albert Kobina Mensah1*, Evans Appiah Kissi2, Kwabena Krah3 and Okoree D. Mireku4. 1Department of Geography, Kenyatta University, Nairobi. 2Department of .... catchment in Kiambu County in Kenya had limited themselves to the assessment of water quality. Little work has been done on the extent to ...

Are central hospitals ready for National Health Insurance? ICD ...

African Journals Online (AJOL)

ICD coding quality from an electronic patient discharge record for clinicians. ... RE Dyers, J Evans, GA Ward, S du Plooy, H Mahomed ... After 6 months, the quality of ICD codes was determined by comparing ICD code descriptors with medical concepts in a random sample of original patient records selected over a 6-week ...

Social Marketing Campaigns and Children's Media Use

Science.gov (United States)

Evans, W. Douglas

2008-01-01

Media-related commercial marketing aimed at promoting the purchase of products and services by children, and by adults for children, is ubiquitous and has been associated with negative health consequences such as poor nutrition and physical inactivity. But, as Douglas Evans points out, not all marketing in the electronic media is confined to the…

Estonian annual retail conference / Oksana Kostina

Index Scriptorium Estoniae

Kostina, Oksana

2005-01-01

Eesti jaekaubanduse aastakonverentsil mais 2005 jagati välja aasta kaubandussaavutuste auhinnad. Esimese koha pälvis Eesti suurim kaubanduskeskus Viru Keskus, mida 2004. aastal külastas 7,5 mln inimest ja mille keskmine päevane käive oli 3,3 mln krooni. Teise koha sai Tallinna Kaubamaja ning kolmanda Baltika Grupp

Teen Vaccines (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

2014-07-24

No child should miss the opportunity for lasting protection against dangerous infectious diseases and some cancers, but unfortunately, many do. In this podcast, Dr. Laurie Elam-Evans discusses the importance of ensuring teenagers are up-to-date on their vaccinations.  Created: 7/24/2014 by MMWR.   Date Released: 7/24/2014.

Chapter 8. Controlling plant competition

Science.gov (United States)

Stephen B. Monsen

2004-01-01

Generally, range or wildlife habitat improvement projects seek to achieve desirable plants through the elimination or replacement of undesirable species or both. Control measures are thus designed to: (1) reduce the competitive effects of existing species (Evans and Young 1987a,b; Robertson and Pearse 1945), (2) allow the establishment of seeded species (Harper and...

The Physical Basis of the Ionosphere in the Solar-Terrestrial System.

Science.gov (United States)

1981-02-01

Hill (Evans, 1972), Saint-Santin ( Testud et al., 1975 ; Blanc, 1978, 1980 a, b), and also at the magnetic equator at Jicamarca (Fejer et al., 1979...1976, 3. Geophys. Res., 8* 7-40, 1979. Southwood, D.3., The role of hot plasma in magnetosphere convection, 3. GeophYs Res., 82, 5512, 1977. Testud , 3

[Dr. Tadeusz Rakowiecki (July 26, 1878-April 6, 1965), physician, astronomer and writer--on the 25th anniversary of his death].

Science.gov (United States)

Wiechowski, W

He decided to study medicine to be self-reliant and helpful for the society though he showed outstanding abilities to exact sciences, in particular mathematics. He was graduated at the Warsaw University in 1903 "cum eximia laude" in medicine. Apart from medicine he had disclosed interest in literature that was realized by many lectures and publications related to the famous and outstanding Polish writer Stefan Zeromski. Since 1930 Dr. Rakowiecki has started as self-taught astronomy studies becoming soon one of seven most eminent Polish astronomers. In the thirties there appeared his two-volume monography entitled "Drogi Planet i Komet" ("Motions of planets and comets") that has become the first fundamental Polish handbook of astronomy actual up to seventies. His scientific achievements based on higher mathematics included 20 important reports on astronomy and several monographs on mathematics. In 1930 he had refused several proposals to head University Chairs of Astronomy, among others in Lwów, due to modesty and his willingness to help and to serve his patients. He had been a demon for work, his rest after admission of patients were astronomy calculations, while when tired with the latters he became occupied with medicine.