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Sample records for systems adl cps

  1. SecureCPS: Defending a nanosatellite cyber-physical system

    Science.gov (United States)

    Forbes, Lance; Vu, Huy; Udrea, Bogdan; Hagar, Hamilton; Koutsoukos, Xenofon D.; Yampolskiy, Mark

    2014-06-01

    Recent inexpensive nanosatellite designs employ maneuvering thrusters, much as large satellites have done for decades. However, because a maneuvering nanosatellite can threaten HVAs on-­orbit, it must provide a level of security typically reserved for HVAs. Securing nanosatellites with maneuvering capability is challenging due to extreme cost, size, and power constraints. While still in the design process, our low-­cost SecureCPS architecture promises to dramatically improve security, to include preempting unknown binaries and detecting abnormal behavior. SecureCPS also applies to a broad class of cyber-­physical systems (CPS), such as aircraft, cars, and trains. This paper focuses on Embry-­Riddle's ARAPAIMA nanosatellite architecture, where we assume any off-­the-­shelf component could be compromised by a supply chain attack.1 Based on these assumptions, we have used Vanderbilt's Cyber Physical -­ Attack Description Language (CP-­ADL) to represent realistic attacks, analyze how these attacks propagate in the ARAPAIMA architecture, and how to defeat them using the combination of a low-­cost Root of Trust (RoT) Module, Global InfoTek's Advanced Malware Analysis System (GAMAS), and Anomaly Detection by Machine Learning (ADML).2 Our most recent efforts focus on refining and validating the design of SecureCPS.

  2. Optimal Planning of Communication System of CPS for Distribution Network

    Directory of Open Access Journals (Sweden)

    Ting Yang

    2017-01-01

    Full Text Available IoT is the technical basis to realize the CPS (Cyber Physical System for distribution networks, with which the complex system becomes more intelligent and controllable. Because of the multihop and self-organization characteristics, the large-scale heterogeneous CPS network becomes more difficult to plan. Using topological potential theory, one of typical big data analysis technologies, this paper proposed a novel optimal CPS planning model. Topological potential equalization is considered as the optimization objective function in heterogeneous CPS network with the constraints of communication requirements, physical infrastructures, and network reliability. An improved binary particle swarm optimization algorithm is proposed to solve this complex optimal problem. Two IEEE classic examples are adopted in the simulation, and the results show that, compared with benchmark algorithms, our proposed method can provide an effective topology optimization scheme to improve the network reliability and transmitting performance.

  3. SLAE-CPS: Smart Lean Automation Engine Enabled by Cyber-Physical Systems Technologies.

    Science.gov (United States)

    Ma, Jing; Wang, Qiang; Zhao, Zhibiao

    2017-06-28

    In the context of Industry 4.0, the demand for the mass production of highly customized products will lead to complex products and an increasing demand for production system flexibility. Simply implementing lean production-based human-centered production or high automation to improve system flexibility is insufficient. Currently, lean automation (Jidoka) that utilizes cyber-physical systems (CPS) is considered a cost-efficient and effective approach for improving system flexibility under shrinking global economic conditions. Therefore, a smart lean automation engine enabled by CPS technologies (SLAE-CPS), which is based on an analysis of Jidoka functions and the smart capacity of CPS technologies, is proposed in this study to provide an integrated and standardized approach to design and implement a CPS-based smart Jidoka system. A set of comprehensive architecture and standardized key technologies should be presented to achieve the above-mentioned goal. Therefore, a distributed architecture that joins service-oriented architecture, agent, function block (FB), cloud, and Internet of things is proposed to support the flexible configuration, deployment, and performance of SLAE-CPS. Then, several standardized key techniques are proposed under this architecture. The first one is for converting heterogeneous physical data into uniform services for subsequent abnormality analysis and detection. The second one is a set of Jidoka scene rules, which is abstracted based on the analysis of the operator, machine, material, quality, and other factors in different time dimensions. These Jidoka rules can support executive FBs in performing different Jidoka functions. Finally, supported by the integrated and standardized approach of our proposed engine, a case study is conducted to verify the current research results. The proposed SLAE-CPS can serve as an important reference value for combining the benefits of innovative technology and proper methodology.

  4. SLAE–CPS: Smart Lean Automation Engine Enabled by Cyber-Physical Systems Technologies

    Science.gov (United States)

    Ma, Jing; Wang, Qiang; Zhao, Zhibiao

    2017-01-01

    In the context of Industry 4.0, the demand for the mass production of highly customized products will lead to complex products and an increasing demand for production system flexibility. Simply implementing lean production-based human-centered production or high automation to improve system flexibility is insufficient. Currently, lean automation (Jidoka) that utilizes cyber-physical systems (CPS) is considered a cost-efficient and effective approach for improving system flexibility under shrinking global economic conditions. Therefore, a smart lean automation engine enabled by CPS technologies (SLAE–CPS), which is based on an analysis of Jidoka functions and the smart capacity of CPS technologies, is proposed in this study to provide an integrated and standardized approach to design and implement a CPS-based smart Jidoka system. A set of comprehensive architecture and standardized key technologies should be presented to achieve the above-mentioned goal. Therefore, a distributed architecture that joins service-oriented architecture, agent, function block (FB), cloud, and Internet of things is proposed to support the flexible configuration, deployment, and performance of SLAE–CPS. Then, several standardized key techniques are proposed under this architecture. The first one is for converting heterogeneous physical data into uniform services for subsequent abnormality analysis and detection. The second one is a set of Jidoka scene rules, which is abstracted based on the analysis of the operator, machine, material, quality, and other factors in different time dimensions. These Jidoka rules can support executive FBs in performing different Jidoka functions. Finally, supported by the integrated and standardized approach of our proposed engine, a case study is conducted to verify the current research results. The proposed SLAE–CPS can serve as an important reference value for combining the benefits of innovative technology and proper methodology. PMID:28657577

  5. MPM4CPS: multi-pardigm modelling for cyber-physical systems

    NARCIS (Netherlands)

    Vangeheluwe, Hans; Ameral, Vasco; Giese, Holger; Broenink, Johannes F.; Schätz, Bernhard; Norta, Alexander; Carreira, Paulo; Lukovic, Ivan; Mayerhofer, Tanja; Wimmer, Manuel; Vellecillo, Antonio

    2016-01-01

    The last decades have seen the emergence of truly complex, designed systems, known as Cyber-Physical Systems (CPS). Engineering such systems requires integrating physical, software, and network aspects. To date, neither a unifying theory nor systematic design methods, techniques and tools exist to

  6. Risk Assessment of Power System considering the CPS of Transformers

    Science.gov (United States)

    Zhou, Long; Peng, Zewu; Liu, Xindong; Li, Canbing; Chen, Can

    2018-02-01

    This paper constructs a risk assessment framework of power system for device-level information security, analyzes the typical protection configuration of power transformers, and takes transformer gas protection and differential protection as examples to put forward a method that analyzes the cyber security in electric power system, which targets transformer protection parameters. We estimate the risk of power system accounting for the cyber security of transformer through utilizing Monte Carlo method and two indexes, which are the loss of load probability and the expected demand not supplied. The proposed approach is tested with IEEE 9 bus system and IEEE 118 bus system.

  7. Panel summary of cyber-physical systems (CPS) and Internet of Things (IoT) opportunities with information fusion

    Science.gov (United States)

    Blasch, Erik; Kadar, Ivan; Grewe, Lynne L.; Brooks, Richard; Yu, Wei; Kwasinski, Andres; Thomopoulos, Stelios; Salerno, John; Qi, Hairong

    2017-05-01

    During the 2016 SPIE DSS conference, nine panelists were invited to highlight the trends and opportunities in cyber-physical systems (CPS) and Internet of Things (IoT) with information fusion. The world will be ubiquitously outfitted with many sensors to support our daily living thorough the Internet of Things (IoT), manage infrastructure developments with cyber-physical systems (CPS), as well as provide communication through networked information fusion technology over the internet (NIFTI). This paper summarizes the panel discussions on opportunities of information fusion to the growing trends in CPS and IoT. The summary includes the concepts and areas where information supports these CPS/IoT which includes situation awareness, transportation, and smart grids.

  8. SVM-Based Dynamic Reconfiguration CPS for Manufacturing System in Industry 4.0

    Directory of Open Access Journals (Sweden)

    Hyun-Jun Shin

    2018-01-01

    Full Text Available CPS is potential application in various fields, such as medical, healthcare, energy, transportation, and defense, as well as Industry 4.0 in Germany. Although studies on the equipment aging and prediction of problem have been done by combining CPS with Industry 4.0, such studies were based on small numbers and majority of the papers focused primarily on CPS methodology. Therefore, it is necessary to study active self-protection to enable self-management functions, such as self-healing by applying CPS in shop-floor. In this paper, we have proposed modeling of shop-floor and a dynamic reconfigurable CPS scheme that can predict the occurrence of anomalies and self-protection in the model. For this purpose, SVM was used as a machine learning technology and it was possible to restrain overloading in manufacturing process. In addition, we design CPS framework based on machine learning for Industry 4.0, simulate it, and perform. Simulation results show the simulation model autonomously detects the abnormal situation and it is dynamically reconfigured through self-healing.

  9. CPS and the Fermilab farms

    Energy Technology Data Exchange (ETDEWEB)

    Fausey, M.R.

    1992-06-01

    Cooperative Processes Software (CPS) is a parallel programming toolkit developed at the Fermi National Accelerator Laboratory. It is the most recent product in an evolution of systems aimed at finding a cost-effective solution to the enormous computing requirements in experimental high energy physics. Parallel programs written with CPS are large-grained, which means that the parallelism occurs at the subroutine level, rather than at the traditional single line of code level. This fits the requirements of high energy physics applications, such as event reconstruction, or detector simulations, quite well. It also satisfies the requirements of applications in many other fields. One example is in the pharmaceutical industry. In the field of computational chemistry, the process of drug design may be accelerated with this approach. CPS programs run as a collection of processes distributed over many computers. CPS currently supports a mixture of heterogeneous UNIX-based workstations which communicate over networks with TCP/IR CPS is most suited for jobs with relatively low I/O requirements compared to CPU. The CPS toolkit supports message passing remote subroutine calls, process synchronization, bulk data transfers, and a mechanism called process queues, by which one process can find another which has reached a particular state. The CPS software supports both batch processing and computer center operations. The system is currently running in production mode on two farms of processors at Fermilab. One farm consists of approximately 90 IBM RS/6000 model 320 workstations, and the other has 85 Silicon Graphics 4D/35 workstations. This paper first briefly describes the history of parallel processing at Fermilab which lead to the development of CPS. Then the CPS software and the CPS Batch queueing system are described. Finally, the experiences of using CPS in production on the Fermilab processor farms are described.

  10. CPS and the Fermilab farms

    International Nuclear Information System (INIS)

    Fausey, M.R.

    1992-06-01

    Cooperative Processes Software (CPS) is a parallel programming toolkit developed at the Fermi National Accelerator Laboratory. It is the most recent product in an evolution of systems aimed at finding a cost-effective solution to the enormous computing requirements in experimental high energy physics. Parallel programs written with CPS are large-grained, which means that the parallelism occurs at the subroutine level, rather than at the traditional single line of code level. This fits the requirements of high energy physics applications, such as event reconstruction, or detector simulations, quite well. It also satisfies the requirements of applications in many other fields. One example is in the pharmaceutical industry. In the field of computational chemistry, the process of drug design may be accelerated with this approach. CPS programs run as a collection of processes distributed over many computers. CPS currently supports a mixture of heterogeneous UNIX-based workstations which communicate over networks with TCP/IR CPS is most suited for jobs with relatively low I/O requirements compared to CPU. The CPS toolkit supports message passing remote subroutine calls, process synchronization, bulk data transfers, and a mechanism called process queues, by which one process can find another which has reached a particular state. The CPS software supports both batch processing and computer center operations. The system is currently running in production mode on two farms of processors at Fermilab. One farm consists of approximately 90 IBM RS/6000 model 320 workstations, and the other has 85 Silicon Graphics 4D/35 workstations. This paper first briefly describes the history of parallel processing at Fermilab which lead to the development of CPS. Then the CPS software and the CPS Batch queueing system are described. Finally, the experiences of using CPS in production on the Fermilab processor farms are described

  11. Restoring ADL function after wrist surgery in children with cerebral palsy: a novel Bilateral robot system design.

    Science.gov (United States)

    Holley, D; Theriault, A; Kamara, S; Anewenter, V; Hughes, D; Johnson, M J

    2013-06-01

    Cerebral palsy is a leading cause of disability in children and reducing its effects on arm function will improve quality of life. Our goal is to train children with CP after wrist tendon transfer surgery using a robotic therapy system consisting of two robot arms and wrist robots. The therapeutic goal is to determine if the robot training combined with surgery intervention improved functional outcomes significantly more than surgery alone. To accomplish this long-term goal we have developed a Bilateral ADL Exercise Robot, BiADLER aimed at training children with CP in reach to grasp coordination on ADLs. Specifically, the robot will provide active training using an assist-as-needed. This paper presents the design concepts.

  12. A Selective CPS Transformation

    DEFF Research Database (Denmark)

    Nielsen, Lasse Riechstein

    2001-01-01

    The CPS transformation makes all functions continuation-passing, uniformly. Not all functions, however, need continuations: they only do if their evaluation includes computational effects. In this paper we focus on control operations, in particular "call with current continuation" and "throw". We...... characterize this involvement as a control effect and we present a selective CPS transformation that makes functions and expressions continuation-passing if they have a control effect, and that leaves the rest of the program in direct style. We formalize this selective CPS transformation with an operational...

  13. The Classroom Performance System (CPS): Effects on student participation, attendance, and achievement in multicultural anatomy and physiology classes at South Texas College

    Science.gov (United States)

    Termos, Mohamad Hani

    2011-12-01

    The Classroom Performance System (CPS) is an instructional technology tool that increases student performance and addresses different learning styles. Instructional technologies are used to promote active learning; however, student embarrassment issue in a multicultural setting is not addressed. This study assessed the effect of the CPS on student participation, attendance, and achievement in multicultural college-level anatomy and physiology classes at South Texas College, where the first spoken language is not English. Quantitative method and quasi-experimental design were employed and comparative statistic methods and pre-post tests were used to collect the data. Participants were college students and sections of study were selected by convenient sampling. Participation was 100% during most of the lectures held and participation rate did not strike above 68% in control group. Attendance was significantly higher in CPS sections than the control group as shown by t-tests. Experimental sections had a higher increase in the pre-post test scores and student averages on lecture exams increased at a higher rate as compared to the control group. Therefore, the CPS increased student participation, attendance, and achievement in multicultural anatomy and physiology classes. The CPS can be studied in other settings where the first spoken language is English or in other programs, such as special education programs. Additionally, other variables can be studied and other methodologies can be employed.

  14. CHIP Reporting in the CPS

    Data.gov (United States)

    U.S. Department of Health & Human Services — CHIP reporting in the CPS is unreliable. Only 10 to 30 percent of those with CHIP (but not Medicaid) report this type of coverage in the CPS. Many with CHIP report...

  15. Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2): atmosphere-land-ocean-sea ice coupled prediction system for operational seasonal forecasting

    Science.gov (United States)

    Takaya, Yuhei; Hirahara, Shoji; Yasuda, Tamaki; Matsueda, Satoko; Toyoda, Takahiro; Fujii, Yosuke; Sugimoto, Hiroyuki; Matsukawa, Chihiro; Ishikawa, Ichiro; Mori, Hirotoshi; Nagasawa, Ryoji; Kubo, Yutaro; Adachi, Noriyuki; Yamanaka, Goro; Kuragano, Tsurane; Shimpo, Akihiko; Maeda, Shuhei; Ose, Tomoaki

    2018-02-01

    This paper describes the Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2), which was put into operation in June 2015 for the purpose of performing seasonal predictions. JMA/MRI-CPS2 has various upgrades from its predecessor, JMA/MRI-CPS1, including improved resolution and physics in its atmospheric and oceanic components, introduction of an interactive sea-ice model and realistic initialization of its land component. Verification of extensive re-forecasts covering a 30-year period (1981-2010) demonstrates that JMA/MRI-CPS2 possesses improved seasonal predictive skills for both atmospheric and oceanic interannual variability as well as key coupled variability such as the El Niño-Southern Oscillation (ENSO). For ENSO prediction, the new system better represents the forecast uncertainty and transition/duration of ENSO phases. Our analysis suggests that the enhanced predictive skills are attributable to incremental improvements resulting from all of the changes, as is apparent in the beneficial effects of sea-ice coupling and land initialization on 2-m temperature predictions. JMA/MRI-CPS2 is capable of reasonably representing the seasonal cycle and secular trends of sea ice. The sea-ice coupling remarkably enhances the predictive capability for the Arctic 2-m temperature, indicating the importance of this factor, particularly for seasonal predictions in the Arctic region.

  16. ADL ORVIS: an air-delay-leg, line-imaging optically recording velocity interferometer system.

    Science.gov (United States)

    Trott, Wayne M; Castañeda, Jaime N; Cooper, Marcia A

    2014-04-01

    An interferometry system that enables acquisition of spatially resolved velocity-time profiles with very high velocity sensitivity has been designed and applied to two diverse, instructive experimental problems: (1) measurement of low-amplitude reverberations in laser-driven flyer plates and (2) measurement of ramp-wave profiles in symmetric impact studies of fused silica. The delay leg in this version of a line-imaging optically recording velocity interferometer system (ORVIS) consists of a long air path that includes relay optics to transmit the optical signal through the interferometer cavity. Target image quality from the delay path at the image recombination plane is preserved by means of a compact and flexible optical design utilizing two parabolic reflectors (serving as the relay optics) in a folded path. With an instrument tuned to a velocity per fringe constant of 22.4 m s(-1) fringe(-1), differences of 1-2 m s(-1) across the probe line segment can be readily distinguished. Measurements that capture small spatial variations in flyer velocity are presented and briefly discussed. In the fused silica impact experiments, the ramp-wave profile observed by this air-delay instrument compares favorably to the profile recorded simultaneously by a conventional line-imaging ORVIS.

  17. A Stochastic Memory Model for ADL Detection in Human Households

    Directory of Open Access Journals (Sweden)

    Jana Clement

    2017-11-01

    Full Text Available Many Human Activity Recognition (HAR systems are able to detect sequential executed Activity of Daily Living (ADL. However, a person is capable of doing two things in parallel or pausing one ADL and finishing it later. Thus, a HAR system must be capable of remembering and deciding which ADL is completed and which might be continued after the current ADL. We address this case by combining a stochastic Markov model and a psychological memory function to detect parallel ADL. For the evaluation, we use an input dataset and a publicly available benchmark. Our approach outperforms the leading HAR systems for the used benchmark by 5%, while using a more cost-effective installation environment. Furthermore, we address an unsupervised learning method to train the HAR system and explain the algorithm of parallel ADL detection in detail.

  18. BCD/CPS: An event-level GEANT3 parallelization via CPS

    International Nuclear Information System (INIS)

    Roberts, L.A.

    1991-04-01

    BCD/CPS is an implementation of the Bottom Collider Detector GEANT3 simulation for CPS processor ranches. BCD/CPS demonstrates some of the capabilities of event-parallel applications applicable to current SSC detector simulations using the CPS and CZ/CPS communications protocols. Design, implementation and usage of the BCD/CPS simulation are presented along with extensive source listings for novice GEANT3/CPS programmers. 11 refs

  19. Distributed co-simulation of embedded control software with exhaust gas recirculation water handling system using INTO-CPS

    DEFF Research Database (Denmark)

    Pedersen, Nicolai; Lausdahl, Kenneth; Sanchez, Enrique Vidal

    2017-01-01

    to reduce the overall costs of validation. This paper demonstrates how this can be achieved for a commercial system developed by MAN Diesel & Turbo using a newly developed tool chain based on the Functional Mock-up Interface standard for co-simulation supporting different operating systems. The generality...

  20. Distributed co-simulation of embedded control software with exhaust gas recirculation water handling system using INTO-CPS

    DEFF Research Database (Denmark)

    Pedersen, Nicolai; Lausdahl, Kenneth; Sanchez, Enrique Vidal

    2017-01-01

    Engineering complex Cyber-Physical Systems, such as emission reduction control systems for large two-stroke engines, require advanced modelling of both the cyber and physical aspects. Different tools are specialised for each of these domains and a combination of tools validating different...... properties is often desirable. However, it is non-trivial to be able to combine such different models of different constituent elements. In order to reduce the need for expensive tests on the real system it is advantageous to be able to combine such heterogeneous models in a joint co-simulation in order...... to reduce the overall costs of validation. This paper demonstrates how this can be achieved for a commercial system developed by MAN Diesel & Turbo using a newly developed tool chain based on the Functional Mock-up Interface standard for co-simulation supporting different operating systems. The generality...

  1. Distributed co-simulation of embedded control software with exhaust gas recirculation water handling system using INTO-CPS

    DEFF Research Database (Denmark)

    Pedersen, Nicolai; Lausdahl, Kenneth; Sanchez, Enrique Vidal

    2017-01-01

    properties is often desirable. However, it is non-trivial to be able to combine such different models of different constituent elements. In order to reduce the need for expensive tests on the real system it is advantageous to be able to combine such heterogeneous models in a joint co-simulation in order...

  2. Ineffective ADL skills in women with fibromyalgia

    DEFF Research Database (Denmark)

    Von Bülow, Cecilie; Amris, Kirstine; la Cour, Karen

    2016-01-01

    at improving ADL ability. OBJECTIVE: To identify frequently reported ADL skill deficits of significance in subgroups of women with fibromyalgia who have decreased ADL motor ability in combination with decreased or competent ADL process ability. METHOD: Women with fibromyalgia were evaluated with the Assessment...... of Motor and Process Skills (AMPS). If they demonstrated decreased ADL motor ability, the calibrated AMPS raters identified and reported ineffective ADL skills of significance. Descriptive comparisons were made between subgroups displaying either decreased or competent ADL process ability. RESULTS: Moves...

  3. International Conference ML4CPS 2016

    CERN Document Server

    Niggemann, Oliver; Kühnert, Christian

    2017-01-01

    The work presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains some selected papers from the international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Karlsruhe, September 29th, 2016. Cyber Physical Systems are characterized by their ability to adapt and to learn: They analyze their environment and, based on observations, they learn patterns, correlations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnosis. Machine Learning is the key technology for these developments. The Editors Prof. Dr.-Ing. Jürgen Beyerer is Professor at the Department for Interactive Real-Time Systems at the Karlsruhe Institute of Technology. In addition he manages the Fraunhofer Institute of Optronics, System Technologies and Image Exploitation IOSB. Prof. Dr. Oliver Niggemann is Professor for Embedded Software Engineering. His research interests are in the field of Di...

  4. CPS Transformation of Beta-Redexes

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse R.

    2000-01-01

    The extra compaction of the most compacting CPS transformation in existence, which is due to Sabry and Felleisen, is generally attributed to (1) making continuations occur first in CPS terms and (2) classifying more redexes as administrative. We show that this extra compaction is actually...... independent of the relative positions of values and continuations and furthermore that it is solely due to a context-sensitive transformation of beta-redexes. We stage the more compact CPS transformation into a first-order uncurrying phase and a context-insensitive CPS transformation. We also define a context......-insensitive CPS transformation that provides the extra compaction. This CPS transformation operates in one pass and is dependently typed....

  5. CPS Transformation of Beta-Redexes

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse

    2005-01-01

    The extra compaction of the most compacting CPS transformation in existence, which is due to Sabry and Felleisen, is generally attributed to (1) making continuations occur first in CPS terms and (2) classifying more redexes as administrative. We show that this extra compaction is actually...... independent of the relative positions of values and continuations and furthermore that it is solely due to a context-sensitive transformation of beta-redexes. We stage the more compact CPS transformation into a first-order uncurrying phase and a context-insensitive CPS transformation. We also define a context......-insensitive CPS transformation that provides the extra compaction. This CPS transformation operates in one pass and is dependently typed....

  6. Completeness of algebraic CPS simulations

    Directory of Open Access Journals (Sweden)

    Ali Assaf

    2012-07-01

    Full Text Available The algebraic lambda calculus and the linear algebraic lambda calculus are two extensions of the classical lambda calculus with linear combinations of terms. They arise independently in distinct contexts: the former is a fragment of the differential lambda calculus, the latter is a candidate lambda calculus for quantum computation. They differ in the handling of application arguments and algebraic rules. The two languages can simulate each other using an algebraic extension of the well-known call-by-value and call-by-name CPS translations. These simulations are sound, in that they preserve reductions. In this paper, we prove that the simulations are actually complete, strengthening the connection between the two languages.

  7. CPS Transformation of Beta-Redexes

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse R.

    2000-01-01

    The extra compaction of the most compacting CPS transformation in existence, which is due to Sabry and Felleisen, is generally attributed to (1) making continuations occur first in CPS terms and (2) classifying more redexes as administrative. We show that this extra compaction is actually...

  8. An Operational Investigation of the CPS Hierarchy

    DEFF Research Database (Denmark)

    Danvy, Olivier; Yang, Zhe

    1998-01-01

    We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

  9. An Operational Investigation of the CPS Hierarchy

    DEFF Research Database (Denmark)

    Danvy, Olivier; Yang, Zhe

    1999-01-01

    We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

  10. MMI design of K-CPS for preventing human errors and enhancing convenient operation

    International Nuclear Information System (INIS)

    Sung, Chan Ho; Jung, Yeon Sub; Oh, Eoung Se; Shin, Young Chul; Lee, Yong Kwan

    2001-01-01

    In order to supplement defects of paper procedure, reduce human errors and enhance convenient operation, computer-based procedure system is being developed. CPS (Computerized Procedure System) including human-factor engineering design concept for KNGR (Korean Next Generation Reactor) has been also developed with the same object. K-CPS(KNGR CPS) has higher level of automation than paper procedure. It is fully integrated with control and monitoring systems. Combining statements and relevant components, which changes dynamically according to plant status enhances readability of procedure. This paper shows general design criteria on computer-based procedure system, the MMI design characteristics of K-CPS and the results of suitability evaluation for K-CPS by operator

  11. CPS Transformation of Flow Information, Part II

    DEFF Research Database (Denmark)

    Damian, D.; Danvy, Olivier

    2003-01-01

    the least solution. Preservation of least solutions solves a problem that was left open in Palsberg and Wand's article ‘CPS Transformation of Flow Information.’ Together, Palsberg and Wand's article and the present article show how to map in linear time the least solution of the flow constraints...... consider the administrative reductions of a Plotkin-style transformation into Continuation-Passing Style (CPS), and how they affect the result of a constraint-based control-flow analysis and, in particular, the least element in the space of solutions. We show that administrative reductions preserve...... of a program into the least solution of the flow constraints of the CPS counterpart of this program, after administrative reductions. Furthermore, we show how to CPS transform control-flow information in one pass....

  12. On proving syntactic properties of CPS programs

    DEFF Research Database (Denmark)

    Danvy, Olivier; Dzafic, Belmina; Pfenning, Frank

    1999-01-01

    Higher-order program transformations raise new challenges for proving properties of their output, since they resist traditional, first-order proof techniques. In this work, we consider (1) the “one-pass” continuation-passing style (CPS) transformation, which is second-order, and (2) the occurrences...... of parameters of continuations in its output. To this end, we specify the one-pass CPS transformation relationally and we use the proof technique of logical relations....

  13. Towards Middleware-Based Cooperation Topologies for the Next Generation of CPS

    Directory of Open Access Journals (Sweden)

    Ismael Etxeberria-Agiriano

    2012-12-01

    Full Text Available Cyber-Physical Systems (CPS integrate embedded computers that control physical processes. Application domains for CPS may be found in intelligent buildings, healthcare, transportation and factory automation, among many others. Typically, they are based on low profile computing elements, such as sensors and actuators that must communicate to carry out complex tasks. They must address certain issues such as managing available resources and service redundancy, as well as solving heterogeneity. In particular, managing communication issues can be relatively complex. In this scenario, middleware technologies can help developers in the design of state-of-the-art CPS. This work describes the design principles of CPS that require cooperation. More specifically, it presents a generic family of logical information exchange and cooperation topologies capable of adapting dynamically to changes in the environment. These topologies may be implemented on top of several middleware specifications as a means for managing distributed resources and service redundancy of CPS at run-time.

  14. VES PANEL (by invitation): Advancement and Enhanced Integration of Digital Technology Systems, VR Applications, CPS-Systems and Tools for Design Engineering

    NARCIS (Netherlands)

    Wendrich, Robert E.; Lim, Theodore; Baalsrud Hauge, Jannicke; Vitali, Andrea

    2018-01-01

    The purpose of this VES panel is to encourage discussion and exchange of views about current and new trends for Virtual and Immersive/Blended Systems and the transference of knowledge over multiple domains. As the market and/or industrial interest in virtual environments increase, new technologies

  15. Role of Ontologies for CPS Implementation in Manufacturing

    Directory of Open Access Journals (Sweden)

    Garetti Marco

    2015-12-01

    Full Text Available Cyber Physical Systems are an evolution of embedded systems featuring a tight combination of collaborating computational elements that control physical entities. CPSs promise a great potential of innovation in many areas including manufacturing and production. This is because we obtain a very powerful, flexible, modular infrastructure allowing easy (re configurability and fast ramp-up of manufacturing applications by building a manufacturing system with modular mechatronic components (for machining, transportation and storage and embedded intelligence, by integrating them into a system, through a network connection. However, when building such kind of architectures, the way to supply the needed domain knowledge to real manufacturing applications arises as a problem to solve. In fact, a CPS based architecture for manufacturing is made of smart but independent manufacturing components without any knowledge of the role they have to play together in the real world of manufacturing applications. Ontologies can supply such kind of knowledge, playing a very important role in CPS for manufacturing. The paper deals with this intriguing theme, also presenting an implementation of this approach in a research project for the open automation of manufacturing systems, in which the power of CPS is complemented by the support of an ontology of the manufacturing domain.

  16. An Extensional CPS Transform (Preliminary Report)

    DEFF Research Database (Denmark)

    Filinski, Andrzej

    2001-01-01

    We shoe that, in a language wihg general continuation-effects, the syntactic, or intensional, CPS transform is mirrored by a semantic, or extensional, functional term. In other words, form only the observable behavior any direct-style term (possibly containing the usual first-class continuation...... primitives), we can uniformly extract the observable behavior of its CPS counterpart. As a consequence of this result, we show that the computational lambda-calculus is complete for observational equivalence of pure, simply typed lambda-terms in Scheme-like contexts....

  17. Classical realizability in the CPS target language

    DEFF Research Database (Denmark)

    Frey, Jonas

    2016-01-01

    Motivated by considerations about Krivine's classical realizability, we introduce a term calculus for an intuitionistic logic with record types, which we call the CPS target language. We give a reformulation of the constructions of classical realizability in this language, using the categorical...... techniques of realizability triposes and toposes. We argue that the presentation of classical realizability in the CPS target language simplifies calculations in realizability toposes, in particular it admits a nice presentation of conjunction as intersection type which is inspired by Girard's ludics....

  18. Two novel Pb(II) coordination polymers (CPs) based on 4-(4-oxopyridin-1(4H)-yl) and 3-(4-oxopyridin-1(4H)-yl) phthalic acid: Band gaps, structures, and their photoelectrocatalytic properties in CO2-saturated system

    Science.gov (United States)

    Yan, Zhi Shuo; Long, Ji Ying; Gong, Yun; Lin, Jian Hua

    2018-05-01

    Based on 4-(4-oxopyridin-1(4H)-yl) phthalic acid (H2L1) and 3-(4-oxopyridin-1(4H)-yl) phthalic acid (H2L2), two novel Pb(II) coordination polymers (CPs) formulated as [Pb4Cl4·(L1)2·H2O]n (CP 1), [Pb3Cl4·L2·H2O]n (CP 2) were solvothermally synthesized and characterized by single-crystal X-ray diffraction. The two novel Pb(II) CPs (CPs 1 and 2) possessed different structures. Density functional theory (DFT) calculations revealed the two CPs had different band structures yet the characteristic of semiconductors in common. Their valence band (VB) and conduction band (CB) positions were determined by Mott-Schottky and UV-visible diffuse reflectance analyses. The photoelectrocatalytic performance of the two CPs towards CO2 reduction were tested by photocurrent responses at various applied potentials. And the E =-1.4 V vs SCE (-0.74 V vs NHE) was selected as the required potential according to the regulation of photocurrent responses at various tested potentials in CO2-saturated system. The photoelectrocatalytic performance of CP 2 was superior to that of CP 1 owing to the well-matched CB position of CP 2 and CO2 reduction potentials at the required potential of -1.4 V vs SCE (-0.74 V vs NHE). In addition, the photoelectrolytic experiment were performed 1 h in the CO2-saturated 0.2 M Na2SO4 solution at the required potential of -1.4 V vs SCE (-0.74 V vs NHE) with and without illumination, and we initially demonstrated the influence of visible light in the CO2-saturated photoelectrocatalytic measurement system and the reason of stability in 1 h chronoamperometry.

  19. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2001-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  20. A Simple CPS Transformation of Control-Flow Information

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2002-01-01

    We build on Danvy and Nielsen's first-order program transformation into continuation-passing style (CPS) to design a new CPS transformation of flow information that is simpler and more efficient than what has been presented in previous work. The key to simplicity and efficiency is that our CPS...... transformation constructs the flow information in one go, instead of first computing an intermediate result and then exploiting it to construct the flow information. More precisely, we show how to compute control-flow information for CPS-transformed programs from control-flow information for direct......-style programs and vice-versa. As a corollary, we confirm that CPS transformation has no effect on the control-flow information obtained by constraint-based control-flow analysis. The transformation has immediate applications in assessing the effect of the CPS transformation over other analyses such as...

  1. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2003-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  2. Sensitivity of different ADL measures to apraxia and motor impairments

    NARCIS (Netherlands)

    Donkervoort, M; Dekker, Joost; Deelman, BG

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing

  3. Sensitivity of different ADL measures to apraxia and motor impairments.

    Science.gov (United States)

    Donkervoort, Mireille; Dekker, Joost; Deelman, Betto G

    2002-05-01

    To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Cross-sectional study. Rehabilitation centres and nursing homes. One hundred and six left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. ADL observations, Barthel ADL Index, an apraxia test, Motricity Index, Functional Motor Test. Multivariate analyses showed that the specific ADL observations were associated with severity of apraxia (and not with motor impairments). The Barthel ADL Index was associated with motor impairments (and not with severity of apraxia). The assessment of disability in stroke patients with apraxia cannot rely only on the Barthel ADL Index. In addition, the specific ADL observation procedure is needed to measure disability due to apraxia.

  4. Sensitivity of different ADL measures to apraxia and motor impairments

    NARCIS (Netherlands)

    Donkervoort, M.; Dekker, J.; Deelman, B.G.

    2002-01-01

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing

  5. Investigation of thermohydraulic parameter variations in operating conditions of Bilibino NPP CPS cooling circuit

    International Nuclear Information System (INIS)

    Baranaev, Yu.D.; Koz'menkova, V.V.; Parafilo, L.M.

    2015-01-01

    In consequence of activities on uncovering the reasons for through faults formation in cooling tubes of reactor control and protection system (CPS) channels of Bilibino-2 reactor the conclusion is made that corrosion failure development takes place against the backdrop of periodic increase of total moisture in reactor space at transient and standby modes at top of cooling tubes of CPS channels. Formation of corrosion defects in cooling tubes of four CPS channels of unit 2 in 2011-2012 is specific factor for this plant unit and do not effect on operation of other plant units. It is pointed out that ingress of moisture into gas system of the reactor is the critical factor providing integrity of structure elements of EhPG-6 reactor core cooling system. This fact agrees nicely with the results obtained during operation AM reactor of the First NPP [ru

  6. Sensitivity of different ADL measures to apraxia and motor impairments

    OpenAIRE

    Donkervoort, M.; Dekker, J.; Deelman, B.G.

    2002-01-01

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing homes. Subjects: One hundred and six left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. Measures: ADL observations, Barthel ADL Index, an apraxia te...

  7. Development of technology for fabrication of lithium CPS on basis of CNT-reinforced carboxylic fabric

    Energy Technology Data Exchange (ETDEWEB)

    Tazhibayeva, Irina, E-mail: tazhibayeva@ntsc.kz [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Baklanov, Viktor; Ponkratov, Yuriy [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Abdullin, Khabibulla [Institute of Experimental and Theoretical Physics of Kazakh National University, Almaty (Kazakhstan); Kulsartov, Timur; Gordienko, Yuriy; Zaurbekova, Zhanna [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Lyublinski, Igor [JSC «Red Star», Moscow (Russian Federation); NRNU «MEPhI», Moscow (Russian Federation); Vertkov, Alexey [JSC «Red Star», Moscow (Russian Federation); Skakov, Mazhyn [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan)

    2017-04-15

    Highlights: • Preliminary study of carboxylic fabric wettability with liquid lithium is presented. • Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673,773 and 873 К in vacuum during long time. • A scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. • The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed. - Abstract: The paper describes the analysis of liquid lithium interaction with materials based on carbon, the manufacture technology of capillary-porous system (CPS) matrix on basis of CNT-reinforced carboxylic fabric. Preliminary study of carboxylic fabric wettability with liquid lithium is presented. The development of technology includes: microstructural studies of carboxylic fabric before its CNT-reinforcing; validation of CNT-reinforcing technology; mode validation of CVD-method for CNT synthesize; study of synthesized carbon structures. Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673, 773 and 873 К in vacuum during long time. The scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed.

  8. An Anonymous Access Authentication Scheme Based on Proxy Ring Signature for CPS-WMNs

    Directory of Open Access Journals (Sweden)

    Tianhan Gao

    2017-01-01

    Full Text Available Access security and privacy have become a bottleneck for the popularization of future Cyber-Physical System (CPS networks. Furthermore, users’ need for privacy-preserved access during movement procedure is more urgent. To address the anonymous access authentication issue for CPS Wireless Mesh Network (CPS-WMN, a novel anonymous access authentication scheme based on proxy ring signature is proposed. A hierarchical authentication architecture is presented first. The scheme is then achieved from the aspect of intergroup and intragroup anonymous mutual authentication through proxy ring signature mechanism and certificateless signature mechanism, respectively. We present a formal security proof of the proposed protocol with SVO logic. The simulation and performance analysis demonstrate that the proposed scheme owns higher efficiency and adaptability than the typical one.

  9. Alternate Communications Spectrum Study (ACSS) for Aviation Data Links (ADL)

    Science.gov (United States)

    Matolak, David W.

    2003-01-01

    The aim of the work was to identify the key factors involved in the use of alternate spectrum in various bands for a future integrated CNS data link. The study focused on systems and spectral bands that can deliver VDL-or-higher data rates in a two-way communication setting (including air-ground, ground-air, and air-air modes of operation), with multiple platforms (aircraft) operating in the same local environment. We begin with a review of the initial task list, and the final task list. The final task list contained a focus upon spectral availability and related systems that could be affected by the deployment of a new aviation data link (ADL) system. Most of this addresses the lower few layers of the communications protocol stack. A brief review of current related efforts in the aeronautical community is then provided, in which we describe several systems and programs of interest. Participation in some of these efforts is recommended. We also delineate several of the advantages and disadvantages of these system/efforts, in view of anticipated requirements of a new ADL. Desired attributes of a new ADL system are then discussed, and a connection with existing systems is made. The need to consider a wider set of alternative systems and technologies is described, and the beneficial aspects of a particular transmission technique- spread spectrum-are discussed. We then discuss in more detail several potential spectral regions, in terms of propagation conditions, available technology, spectrum availability, and waveform selection. Some comments on the need for standardization are also provided. We note that none of the existing systems described will likely meet the full range of desired features of a new ADL, but that several systems and spectral regions offer promise in terms of one or more characteristics. A system design and analysis approach is then provided. In this, we again focus on the lower few layers of the protocol stack, and aim to capture the main features

  10. Vision based assistive technology for people with dementia performing activities of daily living (ADLs): an overview

    Science.gov (United States)

    As'ari, M. A.; Sheikh, U. U.

    2012-04-01

    The rapid development of intelligent assistive technology for replacing a human caregiver in assisting people with dementia performing activities of daily living (ADLs) promises in the reduction of care cost especially in training and hiring human caregiver. The main problem however, is the various kinds of sensing agents used in such system and is dependent on the intent (types of ADLs) and environment where the activity is performed. In this paper on overview of the potential of computer vision based sensing agent in assistive system and how it can be generalized and be invariant to various kind of ADLs and environment. We find that there exists a gap from the existing vision based human action recognition method in designing such system due to cognitive and physical impairment of people with dementia.

  11. An Operational Foundation for Delimited Continuations in the CPS Hierarchy

    DEFF Research Database (Denmark)

    Biernacka, Malgorzata; Biernacki, Dariusz; Danvy, Olivier

    2005-01-01

    We present an abstract machine and a reduction semantics for the lambda-calculus extended with control operators that give access to delimited continuations in the CPS hierarchy. The abstract machine is derived from an evaluator in continuation-passing style (CPS); the reduction semantics (i.......e., a small-step operational semantics with an explicit representation of evaluation contexts) is constructed from the abstract machine; and the control operators are the shift and reset family. We also present new applications of delimited continuations in the CPS hierarchy: finding list prefixes...

  12. An Operational Foundation for Delimited Continuations in the CPS Hierarchy

    DEFF Research Database (Denmark)

    Biernacka, Malgorzata; Biernacki, Dariusz; Danvy, Olivier

    2004-01-01

    We present an abstract machine and a reduction semantics for the lambda-calculus extended with control operators that give access to delimited continuations in the CPS hierarchy. The abstract machine is derived from an evaluator in continuation-passing style (CPS); the reduction semantics (i.......e., a small-step operational semantics with an explicit representation of evaluation contexts) is constructed from the abstract machine; and the control operators are the shift and reset family. We also present new applications of delimited continuations in the CPS hierarchy: finding list prefixes...

  13. Targeting CPS1 in the treatment of Carbamoyl phosphate synthetase 1 (CPS1) deficiency, a urea cycle disorder.

    Science.gov (United States)

    Diez-Fernandez, Carmen; Häberle, Johannes

    2017-04-01

    Carbamoyl phosphate synthetase 1 (CPS1) deficiency (CPS1D) is a rare autosomal recessive urea cycle disorder (UCD), which can lead to life-threatening hyperammonemia. Unless promptly treated, it can result in encephalopathy, coma and death, or intellectual disability in surviving patients. Over recent decades, therapies for CPS1D have barely improved leaving the management of these patients largely unchanged. Additionally, in many cases, current management (protein-restriction and supplementation with citrulline and/or arginine and ammonia scavengers) is insufficient for achieving metabolic stability, highlighting the importance of developing alternative therapeutic approaches. Areas covered: After describing UCDs and CPS1D, we give an overview of the structure- function of CPS1. We then describe current management and potential novel treatments including N-carbamoyl-L-glutamate (NCG), pharmacological chaperones, and gene therapy to treat hyperammonemia. Expert opinion: Probably, the first novel CPS1D therapies to reach the clinics will be the already commercial substance NCG, which is the standard treatment for N-acetylglutamate synthase deficiency and has been proven to rescue specific CPS1D mutations. Pharmacological chaperones and gene therapy are under development too, but these two technologies still have key challenges to be overcome. In addition, current experimental therapies will hopefully add further treatment options.

  14. Determination of tritium generation and release parameters at lithium CPS under neutron irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Ponkratov, Yuriy, E-mail: ponkratov@nnc.kz [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Baklanov, Viktor; Skakov, Mazhyn; Kulsartov, Timur; Tazhibayeva, Irina; Gordienko, Yuriy; Zaurbekova, Zhanna; Tulubayev, Yevgeniy [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Chikhray, Yevgeniy [Institute of Experimental and Theoretical Physics of Kazakh National University, Almaty (Kazakhstan); Lyublinski, Igor [JSC “Star”, Moscow (Russian Federation); NRNU “MEPhI”, Moscow (Russian Federation); Vertkov, Alexey [JSC “Star”, Moscow (Russian Federation)

    2016-11-01

    Highlights: • The main parameters of tritium generation and release from lithium capillary-porous system (CPS) under neutron irradiation at the IVG.1 M research reactor is described in paper. • In the experiments a very small tritium release was fixed likely due to its high solubility in liquid lithium. • If the lithium CPS will be used as a plasma facing material in temperature range up to 773 K under neutron irradiation only helium will release from lithium CPS into a vacuum chamber. - Abstract: This paper describes the main parameters of tritium generation and release from lithium capillary-porous system (CPS) under neutron irradiation at the IVG.1 M research reactor. The experiments were carried out using the method of mass-spectrometric registration of released gases and using a specially constructed ampoule device. Irradiation was carried out at different reactor thermal powers (1, 2 and 6 MW) and sample temperatures from 473 to 773 K. In the experiments a very small tritium release was detected likely due to its high solubility in liquid lithium. It can be caused by formation of lithium tritide during tritium diffusion to the lithium surface.

  15. CPS Transformation of Flow Information, Part II: Administrative Reductions

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2001-01-01

    the least solution. Preservation of least solutions solves a problem that was left open in Palsberg and Wand's article ‘CPS Transformation of Flow Information.’ Together, Palsberg and Wand's article and the present article show how to map in linear time the least solution of the flow constraints...... consider the administrative reductions of a Plotkin-style transformation into Continuation-Passing Style (CPS), and how they affect the result of a constraint-based control-flow analysis and, in particular, the least element in the space of solutions. We show that administrative reductions preserve...... of a program into the least solution of the flow constraints of the CPS counterpart of this program, after administrative reductions. Furthermore, we show how to CPS transform control-flow information in one pass....

  16. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2002-01-01

    We present a new transformation of call-by-value lambdaterms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Because it operates in one pass, it directly yields compact CPS programs that are comparable to what one would...... write by hand. Because it is compositional, it allows proofs by structural induction. Because it is first-order, reasoning about it does not require the use of a logical relation. This new CPS transformation connects two separate lines of research. It has already been used to state a new and simpler...... correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  17. CPS Transformation of Flow Information, Part II: Administrative Reductions

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2001-01-01

    consider the administrative reductions of a Plotkin-style transformation into Continuation-Passing Style (CPS), and how they affect the result of a constraint-based control-flow analysis and, in particular, the least element in the space of solutions. We show that administrative reductions preserve...... the least solution. Preservation of least solutions solves a problem that was left open in Palsberg and Wand's article ‘CPS Transformation of Flow Information.’ Together, Palsberg and Wand's article and the present article show how to map in linear time the least solution of the flow constraints...... of a program into the least solution of the flow constraints of the CPS counterpart of this program, after administrative reductions. Furthermore, we show how to CPS transform control-flow information in one pass....

  18. CPS-Based Smart Warehouse for Industry 4.0: A Survey of the Underlying Technologies

    Directory of Open Access Journals (Sweden)

    Xiulong Liu

    2018-02-01

    Full Text Available This paper discusses how the state-of-the-art techniques in cyber-physical systems facilitate building smart warehouses to achieve the promising vision of industry 4.0. We focus on four significant issues when applying CPS techniques in smart warehouses. First, efficient CPS data collection: when limited communication bandwidth meets numerous CPS devices, we need to make more effort to study efficient wireless communication scheduling strategies. Second, accurate and robust localization: localization is the basis for many fundamental operations in smart warehouses, but still needs to be improved from various aspects like accuracy and robustness. Third, human activity recognition: human activity recognition can be applied in human–computer interaction for remote machine operations. Fourth, multi-robot collaboration: smart robots will take the place of humans to accomplish most tasks particularly in a harsh environment, and smart and fully-distributed robot collaborating algorithms should be investigated. Finally, we point out some challenging issues in the future CPS-based smart warehouse, which could open some new research directions.

  19. The easy ADL home: A physical-virtual approach to domestic living

    DEFF Research Database (Denmark)

    Surie, Dipak; Pederson, Thomas; Janlert, Lars-Erik

    2010-01-01

    Smart environments worthy of the name need to capture, interpret, and support human activities that take place within their realms. Most existing efforts tend to focus on either real world activities or activities taking place in the virtual world accessed through digital devices. However......, as digital computation continues to permeate our everyday real world environments, and as the border between physical and digital continues to blur for the human agents acting in these environments, we need system design approaches that can cope with human activities that span the physical-virtual gap....... In this paper, we present such an approach and use it for designing a smart home intended to support Activities of Daily Living (ADL). The easy ADL home is designed based on a wearable personal server that runs a personal ADL support middleware and a set of computationally augmented everyday objects within...

  20. Future prospects for SonoVue and CPS.

    Science.gov (United States)

    Cosgrove, David

    2004-10-01

    Though long considered unlikely because of the resonance pattern of agents such as SonoVue, high frequency applications for small parts and intracavitary applications now seem very promising. Excellent non-linear signals can be obtained at 7 MHz and higher using recently developed CPS software, and preliminary results suggest that this may prove useful for assessing superficial lymph nodes, the thyroid and parathyroid, breast masses and many superficial masses including those in the skin. Some other potentially useful "fringe" applications of the now-familiar transabdominal transducers with CPS are the pancreas, gall bladder and spleen, though these have not been investigated formally as yet.

  1. Event-based home safety problem detection under the CPS home safety architecture

    OpenAIRE

    Yang, Zhengguo; Lim, Azman Osman; Tan, Yasuo

    2013-01-01

    This paper presents a CPS(Cyber-physical System) home safety architecture for home safety problem detection and reaction and shows some example cases. In order for home safety problem detection, there are three levels of events defined: elementary event, semantic event and entire event, which representing the meaning from parameter to single safety problem, and then the whole safety status of a house. For the relationship between these events and raw data, a Finite State Machine (FSM) based m...

  2. Effect of eccentric location of the RBMK CPS displacer graphite block in the shielding sheath

    International Nuclear Information System (INIS)

    Dostov, A.I.

    2001-01-01

    Temperature conditions and accumulation of Wigner energy in the graphite block of the RBMK reactor CPS (control power system) displacer is examined. It is shown, that at eccentric location of the block in the shielding sheath average temperature of the block drops sharply. Due to the design demerit quantity of the stored energy in the block may be so great, that its release will result in melting of the displacer tube. (author)

  3. Power handling of a liquid-metal based CPS structure under high steady-state heat and particle fluxes

    Directory of Open Access Journals (Sweden)

    T.W. Morgan

    2017-08-01

    Full Text Available Liquid metal infused capillary porous structures (CPSs are considered as a potential divertor solution for DEMO due to their potential power handling capability and resilience to long term damage. In this work the power handling and performance of such Sn-based CPS systems is assessed both experimentally and via modelling. A Sn-CPS target was exposed to heat fluxes of up to 18.1 MW m−2 in He plasma in the Pilot-PSI linear device. Post-mortem the target showed no damage to nor any surface exposure of the underlying W-CPS felt. The small pore size (∼40µm employed resulted in no droplet formation from the target in agreement with calculated Rayleigh-Taylor and Kelvin-Helmoholtz instability thresholds. The temperature response of the Sn-target was used to determine the thermal conductivity of the mixed Sn-CPS material using COMSOL modelling. These values were then used via further finite element analysis to extrapolate to DEMO relevant monoblock designs and estimate the maximum power handling achievable based on estimated temperature windows for all component elements of the design. For an optimized design a heat-load of up to 20 MW m−2 may be received while the use of CPS also offers other potential design advantages such as the removal of interlayer requirements.

  4. Modeling of continuous withdrawal and falling out of CPS control rods accident, using QUABOX/CUBBOX-HYCA code

    International Nuclear Information System (INIS)

    Bubelis, E.; Pabarcius, R.; Tonkunas, A.

    2003-01-01

    At present, at the Ignalina NPP the process of a wider use of the new uranium-erbium fuel of higher saturation and the manual control rods of new design is going on. These actions are directed to reducing the reactor control and protection system (CPS) cooling circuit voiding effect and to improving the technical and economical reactor operation parameters. Continuous withdrawal and falling out of CPS control rods lead to the reactivity and power changes in the reactor core. Therefore, important for safety is the evaluation of the CPS ability to compensate for the resulting excess reactivity in the reactor core, having the changed core loading conditions during such accidents. This article presents the calculation results of the continuous withdrawal and falling out of CPS control rods for the specific reactor core conditions of the Ignalina NPP Unit 2, i.e. during its operation on the maximum allowed power level of 4200 MW. The German code QUABOX/CUBBOX-HYCA with the improved CPS logic was used for the simulation of the above-mentioned transients. (author)

  5. [Psychometric properties of the Activities Daily Life Scale (ADL)].

    Science.gov (United States)

    Boyer, L; Murcia, A; Belzeaux, R; Loundou, A; Azorin, J-M; Chabannes, J-M; Dassa, D; Naudin, J; Samuelian, J-C; Lancon, C

    2010-10-01

    Deficits in social functioning are an important core feature of mental health. Recently in France, the Activities Daily Life (ADL) scale has been proposed by the French authorities to assess social functioning for all hospitalized patients in a psychiatric ward. The perspective is to use this scale in the financing and organization of mental health services in France. The ADL scale is a 6-item (dressing/undressing, walking/mobility, eating/drinking, using toilets, behaviour, relationships/communication) heteroquestionnaire completed by a health care professional at the beginning of each hospitalization, assessing functioning of patients suffering from mental health diseases. However, limited consensus exists on this scale. The psychometric properties of the ADL scale have not been assessed. There is a pressing need for detailed examination of its performance. The aim of this study was to explore ADL psychometric properties in a sample of hospitalized patients in a psychiatric ward. We retrospectively analyzed data for all episodes of care delivered to hospitalized patients in a psychiatric ward in our French Public Hospital from January 1, 2008 to June 30, 2008. The study involved retrospective review of administrative and medical databases. The following data were collected: age, gender, diagnoses based on the International Classification of Diseases - 10th version, ADL scale and Assessment of Social Self-Sufficiency scale (ASSS). The psychometric properties were examined using construct validity, reliability, external validity, reproducibility and sensitivity to change. Data analysis was performed using SPSS 15.0 and WINSTEP software. A total of 1066 patients completed the ADL scale. Among them, 49.7% were male, mean age was 36.5 ± 10.8, and 83.5% were single. Schizophrenia, schizotypal and delusional disorders (40.0%), mood disorders (27.9%) and mental and behavioural disorders due to psychoactive substance use (12%) were the most common diagnoses. Factor

  6. CPW to CPS transition for feeding UWB antennas

    DEFF Research Database (Denmark)

    Butrym, Alexander; Pivnenko, Sergey

    2006-01-01

    The paper considers a transition (balun) from Coplanar Waveguide (CPW) to Coplanar Stripline (CPS) which is non-resonant and suitable for feeding UWB antennas such as Tapered Slot Antennas (Vivaldi antennas, in particular), bow-tie antennas, and other. Some numerical and experimental results are ...

  7. CPW to CPS transition for feeding UWB antennas

    DEFF Research Database (Denmark)

    Butrym, Alexander; Pivnenko, Sergey

    2006-01-01

    The paper considers a transition (balun) from Coplanar Waveguide (CPW) to Coplanar Stripline (CPS) which is non-resonant and suitable for feeding UWB antennas such as Tapered Slot Antennas (Vivaldi antennas, in particular), bow-tie antennas, and other. Some numerical and experimental results...

  8. CPW to CPS transition for feeding UWB antennas

    DEFF Research Database (Denmark)

    Butrym, Alexander; Pivnenko, Sergey

    2004-01-01

    The paper considers a transition (balun) from Coplanar Waveguide (CPW) to Coplanar Stripline (CPS) which is non-resonant and suitable for feeding UWB antennas such as Tapered Slot Antennas (Vivaldi antennas in particular), bow-tie antennas, and other. Some numerical and experimental results...

  9. Power handling of a liquid-metal based CPS structure under high steady-state heat and particle fluxes

    NARCIS (Netherlands)

    Morgan, T. W.; Vertkov, A.; Bystrov, K.; Lyublinski, I.; Genuit, J. W.; Mazzitelli, G.

    2017-01-01

    Liquid metal infused capillary porous structures (CPSs) are considered as a potential divertor solution for DEMO due to their potential power handling capability and resilience to long term damage. In this work the power handling and performance of such Sn-based CPS systems is assessed both

  10. Algorithm integration using ADL (Algorithm Development Library) for improving CrIMSS EDR science product quality

    Science.gov (United States)

    Das, B.; Wilson, M.; Divakarla, M. G.; Chen, W.; Barnet, C.; Wolf, W.

    2013-05-01

    Algorithm Development Library (ADL) is a framework that mimics the operational system IDPS (Interface Data Processing Segment) that is currently being used to process data from instruments aboard Suomi National Polar-orbiting Partnership (S-NPP) satellite. The satellite was launched successfully in October 2011. The Cross-track Infrared and Microwave Sounder Suite (CrIMSS) consists of the Advanced Technology Microwave Sounder (ATMS) and Cross-track Infrared Sounder (CrIS) instruments that are on-board of S-NPP. These instruments will also be on-board of JPSS (Joint Polar Satellite System) that will be launched in early 2017. The primary products of the CrIMSS Environmental Data Record (EDR) include global atmospheric vertical temperature, moisture, and pressure profiles (AVTP, AVMP and AVPP) and Ozone IP (Intermediate Product from CrIS radiances). Several algorithm updates have recently been proposed by CrIMSS scientists that include fixes to the handling of forward modeling errors, a more conservative identification of clear scenes, indexing corrections for daytime products, and relaxed constraints between surface temperature and air temperature for daytime land scenes. We have integrated these improvements into the ADL framework. This work compares the results from ADL emulation of future IDPS system incorporating all the suggested algorithm updates with the current official processing results by qualitative and quantitative evaluations. The results prove these algorithm updates improve science product quality.

  11. The measurement of instrumental ADL: content validity and construct validity

    DEFF Research Database (Denmark)

    Avlund, K; Schultz-Larsen, K; Kreiner, S

    1993-01-01

    A new measure of Instrumental Activities of Daily Living (IADL), which is able to discriminate among the large group of elderly who do not depend on help, was tested for content validity and construct validity. Most assessments of functional ability include Physical ADL (PADL) and Instrumental ADL....... The measure of Instrumental ADL included 30 activities in relation to tiredness and reduced speed. Construct validity was tested by the Rasch model for item analysis; internal validity was specifically addressed by assessing the homogeneity of items under different conditions. The Rasch item analysis of IADL...... (IADL). PADL-scales assess the basic capacity of persons to care for themselves. IADL-scales are used to assess somewhat higher levels of performance, such as the ability to perform household chores or go shopping. Data were collected from 734 70-year-old people in Denmark in the county of Copenhagen...

  12. The measurement of instrumental ADL: content validity and construct validity

    DEFF Research Database (Denmark)

    Avlund, K; Schultz-Larsen, K; Kreiner, S

    1993-01-01

    showed that 14 items could be combined into two qualitatively different additive scales. The IADL-measure complies with demands for content validity, distinguishes between what the elderly actually do, and what they are capable of doing, and is a good discriminator among the group of elderly persons who......A new measure of Instrumental Activities of Daily Living (IADL), which is able to discriminate among the large group of elderly who do not depend on help, was tested for content validity and construct validity. Most assessments of functional ability include Physical ADL (PADL) and Instrumental ADL....... The measure of Instrumental ADL included 30 activities in relation to tiredness and reduced speed. Construct validity was tested by the Rasch model for item analysis; internal validity was specifically addressed by assessing the homogeneity of items under different conditions. The Rasch item analysis of IADL...

  13. Ineffective ADL skills in women with fibromyalgia: a cross-sectional study.

    Science.gov (United States)

    Von Bülow, Cecilie; Amris, Kirstine; La Cour, Karen; Danneskiold-Samsøe, Bente; Wæhrens, Eva Ejlersen

    2016-09-01

    Subgroups of women with fibromyalgia likely show different activity of daily living (ADL) skill deficits. Identifying ineffective ADL skills of significance in the 'typical' woman with fibromyalgia will promote the planning of targeted occupational therapy interventions aiming at improving ADL ability. To identify frequently reported ADL skill deficits of significance in subgroups of women with fibromyalgia who have decreased ADL motor ability in combination with decreased or competent ADL process ability. Women with fibromyalgia were evaluated with the Assessment of Motor and Process Skills (AMPS). If they demonstrated decreased ADL motor ability, the calibrated AMPS raters identified and reported ineffective ADL skills of significance. Descriptive comparisons were made between subgroups displaying either decreased or competent ADL process ability. Moves, calibrates, bends, reaches, and paces were identified as the most frequently reported ineffective ADL skills of significance within the total sample (n = 188). The ADL process skills items organise and accommodate were identified as ineffective only in the subgroup with decreased ADL process ability (n = 105). It is suggested that clinicians modify the individual's tasks and environments to compensate for identified ineffective ADL skills and to use the AMPS to differentiate interventions in women with fibromyalgia.

  14. An Evaluation of ADLs on Modeling Patterns for Software Architecture

    NARCIS (Netherlands)

    Waqas Kamal, Ahmad; Avgeriou, Paris

    2007-01-01

    Architecture patterns provide solutions to recurring design problems at the architecture level. In order to model patterns during software architecture design, one may use a number of existing Architecture Description Languages (ADLs), including the UML, a generic language but also a de facto

  15. File list: Unc.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Octopaminergic_neurons dm3 Unclassified Adult Octopaminergic neuro...ns http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  16. File list: Unc.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.10.AllAg.Octopaminergic_neurons dm3 Unclassified Adult Octopaminergic neuro...ns http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  17. File list: DNS.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Adl.50.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.50.AllAg.Octopaminergic_neurons.bed ...

  18. File list: Unc.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.50.AllAg.Octopaminergic_neurons dm3 Unclassified Adult Octopaminergic neuro...ns http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.50.AllAg.Octopaminergic_neurons.bed ...

  19. File list: DNS.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Adl.05.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  20. File list: Unc.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Octopaminergic_neurons dm3 Unclassified Adult Octopaminergic neuro...ns http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  1. File list: DNS.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Adl.10.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  2. File list: DNS.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Adl.20.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  3. Syntactic Accidents in Program Analysis: On the Impact of the CPS Transformation

    DEFF Research Database (Denmark)

    Daniel, Damian; Danvy, Olivier

    2000-01-01

    We show that a non-duplicating transformation into Continuation-Passing Style (CPS) has no effect on control-flow analysis, a positive effect on binding-time analysis for traditional partial evaluation, and no effect on binding-time analysis for continuation-based partial evaluation: a monovariant...... control-flow analysis yields equivalent results on a direct-style program and on its CPS counterpart, a monovariant binding-time analysis yields less precise results on a direct-style program than on its CPS counterpart, and an enhanced monovariant binding-time analysis yields equivalent results...... on a direct-style program and on its CPS counterpart. Our proof technique amounts to constructing the CPS counterpart of flow information and of binding times. Our results formalize and confirm a folklore theorem about traditional binding-time analysis, namely that CPS has a positive effect on binding times...

  4. Syntactic accidents in program analysis: on the impact of the CPS transformation

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2003-01-01

    We show that a non-duplicating transformation into Continuation-Passing Style (CPS) has no effect on control-flow analysis, a positive effect on binding-time analysis for traditional partial evaluation, and no effect on binding-time analysis for continuation-based partial evaluation: a monovariant...... control-flow analysis yields equivalent results on a direct-style program and on its CPS counterpart, a monovariant binding-time analysis yields less precise results on a direct-style program than on its CPS counterpart, and an enhanced monovariant binding-time analysis yields equivalent results...... on a direct-style program and on its CPS counterpart. Our proof technique amounts to constructing the CPS counterpart of flow information and of binding times. Our results formalize and confirm a folklore theorem about traditional binding-time analysis, namely that CPS has a positive effect on binding times...

  5. Self-reported Quality of ADL Task Performance in Adults with Schizophrenia

    DEFF Research Database (Denmark)

    Nielsen, Kristina Tomra; Petersen, Rikke S.; Wæhrens, Eva Ejlersen

    quality of both personal ADL (PADL) and instrumental ADL (IADL). Aside from decreased independence, the participants also reported problems related to increased effort, increased use of time, and some safety issues. Although most of the participants reported to be competent in relation to PADL tasks.......g. independence) other ADL problems, important to the client, might be overlooked....

  6. Physical performance as long-term predictor of onset of activities of daily living (ADL) disability

    DEFF Research Database (Denmark)

    Idland, Gro; Pettersen, Renate; Avlund, Kirsten

    2013-01-01

    Disability in ADL of aging women is an important public health concern. It is thus of interest to identify modifiable factors underlying onset of ADL disability. We assessed whether three physical performance-based measurements could predict ADL disability 9 years later. The participants were 113...... non-disabled community-dwelling women with a mean age of 79.5 years at baseline. The baseline examinations of physical performance were: functional reach, climbing steps and comfortable walking speed. ADL disability was defined as need of personal assistance in at least one of five basic ADL items....... The participants were followed for 9 years. Logistic regression models were fitted for each of the physical performance measurements together with the covariates in relation to ADL disability. At follow-up 25.7% were disabled in ADL. All three performance measurements were significantly associated with the onset...

  7. 76 FR 75869 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Fertility...

    Science.gov (United States)

    2011-12-05

    ... Population Survey (CPS) Fertility Supplement AGENCY: U.S. Census Bureau, Commerce. ACTION: Notice. SUMMARY... data concerning the Fertility Supplement to be conducted in conjunction with the June 2012 CPS. The... been asked periodically since 1971. This year, the 2012 Fertility Supplement will include revised...

  8. Phylogenetic distribution and membrane topology of the LytR-CpsA-Psr protein family

    Directory of Open Access Journals (Sweden)

    Berger-Bächi Brigitte

    2008-12-01

    Full Text Available Abstract Background The bacterial cell wall is the target of many antibiotics and cell envelope constituents are critical to host-pathogen interactions. To combat resistance development and virulence, a detailed knowledge of the individual factors involved is essential. Members of the LytR-CpsA-Psr family of cell envelope-associated attenuators are relevant for β-lactam resistance, biofilm formation, and stress tolerance, and they are suggested to play a role in cell wall maintenance. However, their precise function is still unknown. This study addresses the occurrence as well as sequence-based characteristics of the LytR-CpsA-Psr proteins. Results A comprehensive list of LytR-CpsA-Psr proteins was established, and their phylogenetic distribution and clustering into subgroups was determined. LytR-CpsA-Psr proteins were present in all Gram-positive organisms, except for the cell wall-deficient Mollicutes and one strain of the Clostridiales. In contrast, the majority of Gram-negatives did not contain LytR-CpsA-Psr family members. Despite high sequence divergence, the LytR-CpsA-Psr domains of different subclusters shared a highly similar, predicted mixed a/β-structure, and conserved charged residues. PhoA fusion experiments, using MsrR of Staphylococcus aureus, confirmed membrane topology predictions and extracellular location of its LytR-CpsA-Psr domain. Conclusion The LytR-CpsA-Psr domain is unique to bacteria. The presence of diverse subgroups within the LytR-CpsA-Psr family might indicate functional differences, and could explain variations in phenotypes of respective mutants reported. The identified conserved structural elements and amino acids are likely to be important for the function of the domain and will help to guide future studies of the LytR-CpsA-Psr proteins.

  9. Audio Development Laboratory (ADL) User Test Planning Guide

    Science.gov (United States)

    Romero, Andy

    2012-01-01

    Test process, milestones and inputs are unknowns to first-time users of the ADL. The User Test Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their test engineering personnel in test planning and execution. Material covered includes a roadmap of the test process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, test article interfaces, and inputs necessary to define test scope, cost, and schedule are included as an appendix to the guide.

  10. 77 FR 27020 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Voting and...

    Science.gov (United States)

    2012-05-08

    ... (age, sex, race, education, occupation, and income) to voting and nonvoting behavior. The November CPS supplement is the only source of data that provides a comprehensive set of voter and nonvoter characteristics...

  11. The LEIR LLRF DSP-Carrier Board : Performance, CPS Renovation Plan and Recommendations

    CERN Document Server

    Angoletta, M E

    2007-01-01

    The LEIR LLRF project started in late 2003 and included designing,manufacturing and commissioning a novel, all-digital beam control system. The project was first to provide the LEIR machine with a beam control system satisfying the many performance requirements. This was achieved in 2006 with the successful LEIR LLRF system commissioning. In addition, the project was to act as a pilot to export the same technology to the other machines of the PS Complex (CPS), such as PS, PSB and AD. New machines currently being proposed (e.g. ELENA) will also rely on it. The evaluation of the LEIR experience and the recommendations on how to best pursue this migration strategy are therefore integral parts of the LEIR LLRF project. A fundamental building block of the LEIR LLRF system is the DSP-carrier board where all beam control loops are implemented. This note examines the main features of the DSP-carrier board release 1.0 used in LEIR and evaluates their impact on the LEIR LLRF implementation and operational performance. ...

  12. File list: Pol.Adl.05.RNA_polymerase_III.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Adult ...SRX395531,SRX331268,SRX331270,SRX395532 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.RNA_polymerase_III.AllCell.bed ...

  13. File list: Pol.Adl.10.RNA_polymerase_III.AllCell [Chip-atlas[Archive

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  14. File list: ALL.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Adult_male_fatbody dm3 All antigens Adult Adult male fatbody SRX04...2251,SRX042245,SRX042250 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Adult_male_fatbody.bed ...

  15. File list: ALL.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  16. File list: Unc.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  17. File list: Unc.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  18. File list: Oth.Adl.50.AllAg.Adult_body [Chip-atlas[Archive

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  19. File list: ALL.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Adult_male_fatbody dm3 All antigens Adult Adult male fatbody SRX04...2251,SRX042245,SRX042250 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Adult_male_fatbody.bed ...

  20. File list: Oth.Adl.20.AllAg.Adult_body [Chip-atlas[Archive

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  1. File list: ALL.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  2. File list: InP.Adl.10.AllAg.Adult_body [Chip-atlas[Archive

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  3. File list: Pol.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  4. File list: Pol.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  5. File list: Oth.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  7. File list: Oth.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  8. File list: Unc.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  9. File list: Unc.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  10. File list: Oth.Adl.05.AllAg.Adult_body [Chip-atlas[Archive

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  11. File list: Oth.Adl.10.AllAg.Adult_body [Chip-atlas[Archive

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  12. File list: Pol.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  13. File list: Oth.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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  14. File list: Oth.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

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    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Testis dm3 Histone Adult Testis SRX017854,SRX017856,SRX390502,SRX3...90501 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.10.AllAg.Testis.bed ...

  17. File list: His.Adl.20.AllAg.Testis [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.20.AllAg.Testis dm3 Histone Adult Testis SRX390502,SRX390501,SRX017856,SRX0...17854 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.20.AllAg.Testis.bed ...

  18. File list: ALL.Adl.10.AllAg.Testis [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Testis dm3 All antigens Adult Testis SRX017857,SRX017854,SRX017856...,SRX390502,SRX390501,SRX390503 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Testis.bed ...

  19. File list: His.Adl.50.AllAg.Testis [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Testis dm3 Histone Adult Testis SRX390502,SRX390501,SRX017856,SRX0...17854 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.50.AllAg.Testis.bed ...

  20. File list: Pol.Adl.20.RNA_polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.RNA_polymerase_II.AllCell ce10 RNA polymerase RNA polymerase II Adult SR...SRX554718,SRX043965,SRX043963,SRX043964 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.20.RNA_polymerase_II.AllCell.bed ...

  1. File list: Oth.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706814,SRX7068...11,SRX706815,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.20.AllAg.Egg_chamber.bed ...

  2. File list: InP.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.05.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...2,SRX706816 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.05.AllAg.Egg_chamber.bed ...

  3. File list: His.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.20.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914956,SRX9...14959,SRX914952,SRX914963,SRX914962,SRX914960,SRX914958,SRX914966,SRX914964,SRX914954 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.20.AllAg.Egg_chamber.bed ...

  4. File list: Oth.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.05.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706810,SRX7068...14,SRX706815,SRX706811 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.05.AllAg.Egg_chamber.bed ...

  5. File list: Oth.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.10.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706814,SRX7068...10,SRX706815,SRX706811 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.10.AllAg.Egg_chamber.bed ...

  6. File list: ALL.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.50.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914955,SRX914951...16,SRX914954,SRX914966,SRX706813,SRX914963,SRX914959,SRX706814,SRX706810,SRX914953 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.50.AllAg.Egg_chamber.bed ...

  7. File list: ALL.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914951,SRX914955...13,SRX914958,SRX914966,SRX914964,SRX706811,SRX914954,SRX706815,SRX706812,SRX706816,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Egg_chamber.bed ...

  8. File list: InP.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.10.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...6,SRX706812 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.10.AllAg.Egg_chamber.bed ...

  9. File list: ALL.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.05.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914955,SRX914951...64,SRX706811,SRX914958,SRX914957,SRX706813,SRX914962,SRX914954,SRX914966,SRX706812,SRX706816 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.05.AllAg.Egg_chamber.bed ...

  10. File list: His.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914959,SRX9...14956,SRX914952,SRX914963,SRX914960,SRX914964,SRX914958,SRX914962,SRX914954,SRX914966 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.05.AllAg.Egg_chamber.bed ...

  11. File list: InP.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706812,SRX70681...6,SRX706813 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.50.AllAg.Egg_chamber.bed ...

  12. File list: Unc.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.10.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914951,SRX914955...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.10.AllAg.Egg_chamber.bed ...

  13. File list: His.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914952,SRX9...14956,SRX914959,SRX914960,SRX914963,SRX914962,SRX914958,SRX914964,SRX914966,SRX914954 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.10.AllAg.Egg_chamber.bed ...

  14. File list: Oth.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706815,SRX7068...11,SRX706814,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.50.AllAg.Egg_chamber.bed ...

  15. File list: InP.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.20.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...2,SRX706816 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.20.AllAg.Egg_chamber.bed ...

  16. File list: Unc.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914951,SRX914955...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.20.AllAg.Egg_chamber.bed ...

  17. File list: Unc.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914955,SRX914951...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.05.AllAg.Egg_chamber.bed ...

  18. File list: Unc.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.50.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914955,SRX914951...,SRX914953 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.50.AllAg.Egg_chamber.bed ...

  19. File list: His.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914956,SRX9...14962,SRX914952,SRX914960,SRX914958,SRX914964,SRX914954,SRX914966,SRX914963,SRX914959 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.50.AllAg.Egg_chamber.bed ...

  20. File list: ALL.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914951,SRX914955...58,SRX706813,SRX706815,SRX914957,SRX706816,SRX914964,SRX706811,SRX914966,SRX914954,SRX706812 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Egg_chamber.bed ...

  1. File list: His.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Young_adult ce10 Histone Adult Young adult SRX1388777,SRX554723,SR...1388779,SRX1388772,SRX1388771,SRX1388778,SRX012297 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.50.AllAg.Young_adult.bed ...

  2. File list: Oth.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.10.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX080072,SRX331...,SRX054211,SRX054210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.10.AllAg.Young_adult.bed ...

  3. File list: ALL.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Young_adult ce10 All antigens Adult Young adult SRX395531,SRX08007...4210,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.10.AllAg.Young_adult.bed ...

  4. File list: ALL.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.50.AllAg.Young_adult ce10 All antigens Adult Young adult SRX331330,SRX14642...54208,SRX054210,SRX054211 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.50.AllAg.Young_adult.bed ...

  5. File list: Pol.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX331268,SRX331...RX043964 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.20.AllAg.Young_adult.bed ...

  6. File list: Unc.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Young_adult ce10 Unclassified Adult Young adult SRX707297,SRX70729...8 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.20.AllAg.Young_adult.bed ...

  7. File list: Oth.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX331330,SRX146...,SRX054208,SRX054210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.20.AllAg.Young_adult.bed ...

  8. File list: InP.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.10.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX0056...6,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.10.AllAg.Young_adult.bed ...

  9. File list: Pol.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.10.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX395531,SRX331...RX043965 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.10.AllAg.Young_adult.bed ...

  10. File list: ALL.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Young_adult ce10 All antigens Adult Young adult SRX331330,SRX14642...4210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.20.AllAg.Young_adult.bed ...

  11. File list: Pol.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX395531,SRX331...RX043965 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.AllAg.Young_adult.bed ...

  12. File list: InP.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.20.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX0056...9 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.20.AllAg.Young_adult.bed ...

  13. File list: Unc.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Young_adult ce10 Unclassified Adult Young adult SRX707297,SRX70729...8 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.05.AllAg.Young_adult.bed ...

  14. File list: InP.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.05.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX4670...9,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.05.AllAg.Young_adult.bed ...

  15. File list: Unc.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.10.AllAg.Young_adult ce10 Unclassified Adult Young adult SRX707297,SRX70729...8 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.10.AllAg.Young_adult.bed ...

  16. File list: His.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Young_adult ce10 Histone Adult Young adult SRX554723,SRX1388779,SR...RX1388775,SRX554734,SRX1388768,SRX012297,SRX012298,SRX012300 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.05.AllAg.Young_adult.bed ...

  17. File list: ALL.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.05.AllAg.Young_adult ce10 All antigens Adult Young adult SRX080072,SRX39553...2299,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.05.AllAg.Young_adult.bed ...

  18. File list: His.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Young_adult ce10 Histone Adult Young adult SRX1388777,SRX1388779,S...SRX554724,SRX554734,SRX1388769,SRX012297,SRX012298,SRX012300 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.10.AllAg.Young_adult.bed ...

  19. File list: InP.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX3732...X331269,SRX331331,SRX467093,SRX982096,SRX1388752,SRX1388749,SRX235166,SRX012299 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.50.AllAg.Young_adult.bed ...

  20. File list: Oth.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX331330,SRX146...,SRX054211 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.50.AllAg.Young_adult.bed ...

  1. File list: Unc.Adl.50.Unclassified.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.50.Unclassified.AllCell ce10 Unclassified Unclassified Adult SRX707297,SRX7...07298 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.50.Unclassified.AllCell.bed ...

  2. File list: Pol.Adl.05.RNA_Polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.RNA_Polymerase_II.AllCell ce10 RNA polymerase RNA Polymerase II Adult SR...SRX1388757,SRX1388756 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.RNA_Polymerase_II.AllCell.bed ...

  3. File list: Pol.Adl.05.RNA_polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.RNA_polymerase_II.AllCell ce10 RNA polymerase RNA polymerase II Adult SR...SRX005635,SRX554718,SRX043963,SRX043965 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.RNA_polymerase_II.AllCell.bed ...

  4. File list: NoD.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Adl.05.AllAg.Octopaminergic_neurons dm3 No description Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/NoD.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  5. File list: ALL.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Octopaminergic_neurons dm3 All antigens Adult Octopaminergic neuro...ns SRX135530,SRX135531 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  6. File list: ALL.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.05.AllAg.Octopaminergic_neurons dm3 All antigens Adult Octopaminergic neuro...ns SRX135530,SRX135531 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  7. File list: His.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Octopaminergic_neurons dm3 Histone Adult Octopaminergic neurons SR...X135530,SRX135531 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  8. File list: Oth.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.10.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  9. File list: Pol.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.AllAg.Octopaminergic_neurons dm3 RNA polymerase Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  10. File list: Oth.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.50.AllAg.Octopaminergic_neurons.bed ...

  11. File list: NoD.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Adl.10.AllAg.Octopaminergic_neurons dm3 No description Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/NoD.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  12. File list: Oth.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.05.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  13. File list: InP.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Octopaminergic_neurons dm3 Input control Adult Octopaminergic neur...ons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.50.AllAg.Octopaminergic_neurons.bed ...

  14. File list: His.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.20.AllAg.Octopaminergic_neurons dm3 Histone Adult Octopaminergic neurons SR...X135531,SRX135530 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  15. File list: Oth.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neu...rons http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  16. File list: His.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  10. Self-reported and Observed Quality of ADL Task Performance in Adults with Depression

    DEFF Research Database (Denmark)

    Nielsen, Kristina Tomra; Wæhrens, Eva

    Introduction Limited relationship between measures of self-reported and observed quality of ADL task performance has been revealed in a rheumatologic population, stressing the need to apply both self-report and observation in that population when evaluating ADL task performance. As occupational...... therapists offer their services to a wide range of diagnostic groups, it was decided to investigate if a similar pattern would show, when examining the relationship between self-reported and observed quality of ADL task performance in a different population. For this purpose, adults with depression were...... chosen. Aims • To investigate which information can be obtained about the quality of ADL task performance based on self-report and observation, respectively • To examine the relationship between measures of self-reported and observed quality of ADL task performance. Subjects Twenty patients >18 years...

  11. A Microprocessor Controlled Automatic Data Logging System (ADL).

    Science.gov (United States)

    1977-06-01

    aarforaa «11 oaaratioaa <tita ? aiaaiflcaat lifita* aaaarlcal o«t»at .« rosa ««« to 4 aioalflcaat «laita f «ita caolco of «sei aal or aapoasstial...RAM) CNDO volts VDU - 9 volts t5 t» •»00 mA maximum(35 mA per ROM) Hardware Compatible with Series 8400 int«rf«<.c cards. Fits CR5.1 R10 or

  12. Activity Limitation Stages empirically derived for Activities of Daily Living (ADL) and Instrumental ADL in the U.S. Adult community-dwelling Medicare population.

    Science.gov (United States)

    Stineman, Margaret G; Streim, Joel E; Pan, Qiang; Kurichi, Jibby E; Schüssler-Fiorenza Rose, Sophia Miryam; Xie, Dawei

    2014-11-01

    Stages quantify severity like conventional measures but further specify the activities that people are still able to perform without difficulty. To develop Activity Limitation Stages for defining and monitoring groups of adult community-dwelling Medicare beneficiaries. Cross-sectional. Community. There were 14,670 respondents to the 2006 Medicare Current Beneficiary Survey. Stages were empirically derived for the Activities of Daily Living (ADLs) and the Instrumental Activities of Daily Living (IADLs) by profiling the distribution of performance difficulties as reported by beneficiaries or their proxies. Stage prevalence estimates were determined, and associations with demographic and health variables were examined for all community-dwelling Medicare beneficiaries. ADL and IADL stage prevalence. Stages (0-IV) define 5 groups across the separate ADL and IADL domains according to hierarchically organized profiles of retained abilities and difficulties. For example, at ADL-I, people are guaranteed to be able to eat, toilet, dress, and bathe/shower without difficulty, whereas they experience limitations getting in and out of bed or chairs and/or difficulties walking. In 2006, an estimated 6.0, 2.9, 2.2, and 0.5 million beneficiaries had mild (ADL-I), moderate (ADL-II), severe (ADL-III), and complete (ADL-IV) difficulties, respectively, with estimates for IADL stages even higher. ADL and IADL stages showed expected associations with age and health-related concepts, supporting construct validity. Stages showed the strongest associations with conditions that impair cognition. Stages as aggregate measures reveal the ADLs and IADLs that people are still able to do without difficulty, along with those activities in which they report having difficulty, consequently emphasizing how groups of people with difficulties can still participate in their own lives. Over the coming decades, stages applied to populations served by vertically integrated clinical practices could

  13. Towards Service-Oriented Middleware for Fog and Cloud Integrated Cyber Physical Systems

    DEFF Research Database (Denmark)

    Mohamed, Nader; Lazarova-Molnar, Sanja; Jawhar, Imad

    2017-01-01

    enables the integration of CPS with other systems such as Cloud and Fog Computing. Furthermore, as CPS can be developed for various applications at different scales, this paper provides a classification for CPS applications and discusses how CPSWare can effectively deal with the different issues in each....... In addition, it proposes an SOM for CPS, called CPSWare. This middleware views all CPS components as a set of services and provides a service-based infrastructure to develop and operate CPS applications. This approach provides systemic solutions for solving many computing and networking issues in CPS. It also...

  14. Genotyping of the Capsule Gene Cluster (cps) in Nontypeable Group B Streptococci Reveals Two Major cps Allelic Variants of Serotypes III and VII

    OpenAIRE

    Sellin, Mats; Olofsson, Carin; Håkansson, Stellan; Norgren, Mari

    2000-01-01

    Forty group B Streptococcus (GBS) isolates obtained from Europe and the United States previously reported to be nontypeable (NT) by capsule serotype determination were subjected to buoyant density gradient centrifugation. From nearly half of the isolates capsule-expressing variants could be selected. For characterization of the remaining NT-GBS isolates, the capsule operon (cps) was amplified by the long-fragment PCR technique and compared by restriction fragment length polymorphism (RFLP) an...

  15. Client-centred ADL intervention after stroke: Significant others' experiences.

    Science.gov (United States)

    Bertilsson, Ann-Sofie; von Koch, Lena; Tham, Kerstin; Johansson, Ulla

    2015-01-01

    Client-centredness is a prominent contemporary concept in rehabilitation. However, there is a lack of knowledge on if and how a client-centred rehabilitation approach is incorporated in the everyday life of significant others of people who receive such rehabilitation. Explore and describe if and how a client-centred ADL intervention (CADL) was integrated in the everyday lives of significant others of people with stroke. Qualitative longitudinal design, with a grounded theory approach. Seven significant others, who cohabited with persons receiving a CADL intervention, were interviewed during the first year. One core category was identified: "Taking responsibility and achieving balance with respect to self-esteem in order to get on with everyday life". The integration of the CADL was a process. A key aspect was that as the person with stroke acted upon his/her own desired activity goals the significant others were encouraged to act on their own needs. Enablement is important also for the significant others of people with stroke. One way of enabling significant others to maintain an active lifestyle and find respite in everyday life might be to enable people with stroke to formulate and act upon their desired activity goals.

  16. A Process for the Representation of openEHR ADL Archetypes in OWL Ontologies.

    Science.gov (United States)

    Porn, Alex Mateus; Peres, Leticia Mara; Didonet Del Fabro, Marcos

    2015-01-01

    ADL is a formal language to express archetypes, independent of standards or domain. However, its specification is not precise enough in relation to the specialization and semantic of archetypes, presenting difficulties in implementation and a few available tools. Archetypes may be implemented using other languages such as XML or OWL, increasing integration with Semantic Web tools. Exchanging and transforming data can be better implemented with semantics oriented models, for example using OWL which is a language to define and instantiate Web ontologies defined by W3C. OWL permits defining significant, detailed, precise and consistent distinctions among classes, properties and relations by the user, ensuring the consistency of knowledge than using ADL techniques. This paper presents a process of an openEHR ADL archetypes representation in OWL ontologies. This process consists of ADL archetypes conversion in OWL ontologies and validation of OWL resultant ontologies using the mutation test.

  17. Self-reported quality of ADL task performance among patients with COPD exacerbations

    DEFF Research Database (Denmark)

    Bendixen, Hans Jørgen; Wæhrens, Eva Ejlersen; Wilcke, Jon Torgny

    2014-01-01

    concerning age, gender, and routine COPD characteristics were drawn from the patients' medical records. RESULTS: The patients reported being inefficient to markedly inefficient when performing ADL tasks within the personal hygiene, toileting, dressing, household, mobility, and transportation domains. While...

  18. Implementation of the On-the-fly Encryption for the Linux OS Based on Certified CPS

    Directory of Open Access Journals (Sweden)

    Alexander Mikhailovich Korotin

    2013-02-01

    Full Text Available The article is devoted to tools for on-the-fly encryption and a method to implement such tool for the Linux OS based on a certified CPS.The idea is to modify the existing tool named eCryptfs. Russian cryptographic algorithms will be used in the user and kernel modes.

  19. Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen

    Directory of Open Access Journals (Sweden)

    Markus W. Weishaupt

    2016-07-01

    Full Text Available Vaccines against S. pneumoniae, one of the most prevalent bacterial infections causing severe disease, rely on isolated capsular polysaccharide (CPS that are conjugated to proteins. Such isolates contain a heterogeneous oligosaccharide mixture of different chain lengths and frame shifts. Access to defined synthetic S. pneumoniae CPS structures is desirable. Known syntheses of S. pneumoniae serotype 3 CPS rely on a time-consuming and low-yielding late-stage oxidation step, or use disaccharide building blocks which limits variability. Herein, we report the first iterative automated glycan assembly (AGA of a conjugation-ready S. pneumoniae serotype 3 CPS trisaccharide. This oligosaccharide was assembled using a novel glucuronic acid building block to circumvent the need for a late-stage oxidation. The introduction of a washing step with the activator prior to each glycosylation cycle greatly increased the yields by neutralizing any residual base from deprotection steps in the synthetic cycle. This process improvement is applicable to AGA of many other oligosaccharides.

  20. Development of the Childbirth Perception Scale (CPS) : Perception of delivery and the first postpartum week

    NARCIS (Netherlands)

    Truijens, Sophie E. M.; Wijnen, Hennie A.; Pommer, Antoinette M.; Oei, S. Guid; Pop, Victor J. M.

    2014-01-01

    Some caregivers suggest a more positive experience of childbirth when giving birth at home. Since properly developed instruments that assess women’s perception of delivery and the early postpartum are missing, the aim of the current study is to develop a Childbirth Perception Scale (CPS). Three

  1. Medium-Chain Chlorinated Paraffins (CPs) Dominate in Australian Sewage Sludge

    NARCIS (Netherlands)

    Brandsma, Sicco H; van Mourik, Louise; O'Brien, Jake W; Eaglesham, Geoff; Leonards, Pim E G; de Boer, Jacob; Gallen, Christie; Mueller, Jochen; Gaus, Caroline; Bogdal, Christian

    2017-01-01

    To simultaneously quantify and profile the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs, and LCCPs) in Australian sewage sludge, we applied and further validated a recently developed novel instrumental technique, using quadrupole time-of-flight high resolution mass

  2. Wikis for a Collaborative Problem-Solving (CPS) Module for Secondary School Science

    Science.gov (United States)

    DeWitt, Dorothy; Alias, Norlidah; Siraj, Saedah; Spector, Jonathan Michael

    2017-01-01

    Collaborative problem solving (CPS) can support online learning by enabling interactions for social and cognitive processes. Teachers may not have sufficient knowledge to support such interactions, so support needs to be designed into learning modules for this purpose. This study investigates to what extent an online module for teaching nutrition…

  3. Component-based event composition modeling for CPS

    Science.gov (United States)

    Yin, Zhonghai; Chu, Yanan

    2017-06-01

    In order to combine event-drive model with component-based architecture design, this paper proposes a component-based event composition model to realize CPS’s event processing. Firstly, the formal representations of component and attribute-oriented event are defined. Every component is consisted of subcomponents and the corresponding event sets. The attribute “type” is added to attribute-oriented event definition so as to describe the responsiveness to the component. Secondly, component-based event composition model is constructed. Concept lattice-based event algebra system is built to describe the relations between events, and the rules for drawing Hasse diagram are discussed. Thirdly, as there are redundancies among composite events, two simplification methods are proposed. Finally, the communication-based train control system is simulated to verify the event composition model. Results show that the event composition model we have constructed can be applied to express composite events correctly and effectively.

  4. STRATEGI PEMBELAJARAN CREATIVE PROBLEM SOLVING (CPS BERBASIS EKSPERIMEN UNTUK MENINGKATKAN KEMAMPUAN KOGNITIF DAN KETERAMPILAN BERPIKIR KREATIF

    Directory of Open Access Journals (Sweden)

    Ahmad Busyairi

    2015-09-01

    Full Text Available This study aimed to get an idea related to the development of cognitive abilities and creative thinking skills in problem solving student after being given treatment with CPS-based experimental learning and conventional learning. The method used in this research is a quasi-experimental design with the randomized pretest-posttest control group design. The research sample group of 58 high school students who are divided into two classes (class 29 experimental and 29 control group. The collected data was then analyzed using N-gain calculation, t-test, and the calculation of effect size. The result showed that the students' cognitive abilities for both classes equally increased by the moderate category. For the creative thinking skills of students in problem solving, experimental class increased by categories was increased while the control class with low category. Based on the test results show that the application of learning hypothesis-based experiments CPS can significantly improve the cognitive abilities and skills of creative thinking in solving problems of students compared to the application of conventional learning. In addition, based on the calculation of effect size indicates that the application of experiment-based learning CPS effective in improving cognitive ability and creative thinking skills in problem solving students with moderate category. ABSTRAK Penelitian ini bertujuan untuk mendapatkan gambaran terkait peningkatan kemampuan kognitif dan keterampilan berpikir kreatif dalam pemecahan masalah siswa setelah diberikan perlakuan dengan pembelajaran CPS berbasis eksperimen dan pembelajaran kovensional. Metode yang digunakan dalam penelitian ini adalah metode kuasi eksperimen dengan desain the randomized pretest-posttest control group design. Sampel penelitian sebanyak 58 siswa SMA yang dibagi ke dalam dua kelas (29 kelas eksperimen dan 29 kelas kontrol. Data yang terkumpul kemudian dianalisis dengan menggunakan perhitungan N

  5. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    OpenAIRE

    Donkervoort, M.; Dekker, J.; Deelman, B.

    2006-01-01

    OBJECTIVE: To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. DESIGN: Prospective cohort study. SETTING: Rehabilitation centres and nursing homes. SUBJECTS: One hundred and eight left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. MEASURES: ADL-observations, Barthel ADL Index, Apraxia Test, Motricity Index. RESULTS: During the study period of 20 weeks, patients showed small improv...

  6. Activity Index - a complementary ADL scale to the Barthel Index in the acute stage in patients with severe stroke.

    Science.gov (United States)

    Martinsson, Louise; Eksborg, Staffan

    2006-01-01

    It was the aim of this study to compare the Barthel Index (BI) and the activities of daily living (ADL) component of the Activity Index [AI(ADL)] regarding floor and ceiling effects, responsiveness and the predictive value for survival during the first week until 3 months after stroke onset. Basic ADL were assessed in 75 patients with ischaemic stroke. There was a strong concordance between BI and AI(ADL) scores at all time points (Kendall's taub = 0.7878, p scales had a substantial ceiling effect at 3 months. At 1 week, the baseline BI score was significantly higher in patients being alive as compared with those who had died, while their AI(ADL) score did not differ significantly. At 3 months, baseline BI and AI(ADL) scores were significantly higher in patients being alive as compared with those who had died. The predictive value of being alive at 1 week and 3 months did not differ between BI and AI(ADL). AI(ADL) is recommended to be used in addition as a complement to BI in patients with severe stroke since the floor effect with BI in the acute stage is significantly more pronounced than with AI(ADL), thus hampering the responsiveness. Copyright 2006 S. Karger AG, Basel.

  7. Incidental liver lesions: diagnostic value of cadence contrast pulse sequencing (CPS) and SonoVue.

    Science.gov (United States)

    Bleuzen, A; Tranquart, F

    2004-10-01

    The widespread use of modern imaging modalities has led to an increase in the frequency of detecting coincidental focal liver lesions (cysts, haemangiomas, focal nodular hyperplasia, adenoma, focal fatty sparing and infiltration) in patients with no symptoms of liver disease. A positive diagnosis is needed to avoid overinvestigation or protracted follow-up. The limitations of conventional sonography have led to the use of other imaging modalities and invasive or costly procedures such as CT, MRI or biopsy. The availability of real-time contrast-enhanced ultrasound imaging (CEUS) has changed the strategy in the characterization of such lesions without inconvenience for the patient. Cadence contrast pulse sequencing (CPS) gives strong contrast signals as well as simultaneous acquisition of conventional scans for a perfect match of these two images. In our personal experience, in comparison with reference imaging, CPS with SonoVue has differentiated benign from malignant lesions in all cases and has accurately characterized 96% of lesions. These results are slightly better than those reported in the literature, probably because of the higher sensitivity of CPS in detecting bubbles, whether flowing or stationary, and also because of the possibility of matching simultaneously recorded contrast and conventional images which reinforces confidence in lesion assessment. The high diagnostic value of CEUS makes this method a candidate to be considered a reference imaging modality for incidental lesions.

  8. Medium-Chain Chlorinated Paraffins (CPs) Dominate in Australian Sewage Sludge.

    Science.gov (United States)

    Brandsma, Sicco H; van Mourik, Louise; O'Brien, Jake W; Eaglesham, Geoff; Leonards, Pim E G; de Boer, Jacob; Gallen, Christie; Mueller, Jochen; Gaus, Caroline; Bogdal, Christian

    2017-03-21

    To simultaneously quantify and profile the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs, and LCCPs) in Australian sewage sludge, we applied and further validated a recently developed novel instrumental technique, using quadrupole time-of-flight high resolution mass spectrometry running in the negative atmospheric pressure chemical ionization mode (APCI-qTOF-HRMS). Without using an analytical column the cleaned extracts were directly injected into the qTOF-HRMS followed by quantification of the CPs by a mathematical algorithm. The recoveries of the four SCCP, MCCP and LCCP-spiked sewage sludge samples ranged from 86 to 123%. This APCI-qTOF-HRMS method is a fast and promising technique for routinely measuring SCCPs, MCCPs, and LCCPs in sewage sludge. Australian sewage sludge was dominated by MCCPs with concentrations ranging from 542 to 3645 ng/g dry weight (dw). Lower SCCPs concentrations (sewage sludge, which were comparable with the LCCPs concentrations (116-960 ng/g dw). This is the first time that CPs were reported in Australian sewage sludge. The results of this study gives a first impression on the distribution of the SCCPs, MCCPs, and LCCPs in Australia wastewater treatment plants (WWTPs).

  9. Keefektifan Model Kooperatif Tipe Make A Match dan Model CPS Terhadap Kemampuan Pemecahan Masalah dan Motivasi Belajar

    Directory of Open Access Journals (Sweden)

    Nur Fitri Amalia

    2013-12-01

    Full Text Available AbstrakTujuan penelitian ini adalah untuk mengetahui keefektifan model kooperatif tipe Make a Match dan model CPS terhadap kemampuan pemecahan masalah dan motivasi belajar sis-wa kelas X pada materi persamaan dan fungsi kuadrat. Populasi dalam penelitian ini adalah siswa kelas X SMA N 1 Subah tahun ajaran 2013/2014. Sampel dalam penelitian ini diam-bil dengan teknik random sampling, yaitu teknik pengambilan sampel dengan acak. Kelas X8 terpilih sebagai kelas eksperimen I dengan penerapan model kooperatif tipe Make a Match dan kelas X7 terpilih sebagai kelas eksperimen II dengan penerapan model CPS. Da-ta hasil penelitian diperoleh dengan tes dan pemberian angket untuk kemudian dianalisis menggunakan uji proporsi dan uji t. Hasil penelitian adalah (1 implementasi model koope-ratif tipe Make a Match efektif terhadap kemampuan pemecahan masalah; (2 implementasi model CPS efektif terhadap kemampuan pemecahan masalah; (3 implementasi model koo-peratif tipe Make a Match lebih baik daripada model CPS terhadap kemampuan pecahan masalah; (4 implementasi model CPS lebih baik daripada model kooperatif tipe Make a Match terhadap motivasi belajar.Kata Kunci:       Make A Match; CPS; Pemecahan Masalah; Motivasi  AbstractThe purpose of this study was to determine the effectiveness of cooperative models Make a Match and CPS to problem-solving ability and motivation of students of class X in the equation of matter and quadratic function. The population of this study was the tenth grade students of state senior high school 1 Subah academic year 2013/2014. The samples in this study were taken by random sampling technique, that is sampling techniques with random. Class X8 was selected as the experimental class I with the application of cooperative model make a Match and class X7 was selected as the experimental class II with the application of the CPS. The data were obtained with the administration of a questionnaire to test and then analyzed using the

  10. AeroADL: applying the integration of the Suomi-NPP science algorithms with the Algorithm Development Library to the calibration and validation task

    Science.gov (United States)

    Houchin, J. S.

    2014-09-01

    A common problem for the off-line validation of the calibration algorithms and algorithm coefficients is being able to run science data through the exact same software used for on-line calibration of that data. The Joint Polar Satellite System (JPSS) program solved part of this problem by making the Algorithm Development Library (ADL) available, which allows the operational algorithm code to be compiled and run on a desktop Linux workstation using flat file input and output. However, this solved only part of the problem, as the toolkit and methods to initiate the processing of data through the algorithms were geared specifically toward the algorithm developer, not the calibration analyst. In algorithm development mode, a limited number of sets of test data are staged for the algorithm once, and then run through the algorithm over and over as the software is developed and debugged. In calibration analyst mode, we are continually running new data sets through the algorithm, which requires significant effort to stage each of those data sets for the algorithm without additional tools. AeroADL solves this second problem by providing a set of scripts that wrap the ADL tools, providing both efficient means to stage and process an input data set, to override static calibration coefficient look-up-tables (LUT) with experimental versions of those tables, and to manage a library containing multiple versions of each of the static LUT files in such a way that the correct set of LUTs required for each algorithm are automatically provided to the algorithm without analyst effort. Using AeroADL, The Aerospace Corporation's analyst team has demonstrated the ability to quickly and efficiently perform analysis tasks for both the VIIRS and OMPS sensors with minimal training on the software tools.

  11. File list: InP.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  13. File list: NoD.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  14. File list: NoD.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  15. File list: InP.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  6. File list: ALL.Adl.20.AllAg.Germline_containing_young_adult [Chip-atlas[Archive

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  7. Katz' ADL index assessed functional performance of Turkish, Moroccan, and Dutch elderly

    NARCIS (Netherlands)

    Reijneveld, Sijmen A.; Spijker, Jannie; Dijkshoorn, Henriette

    Background and Objective: We examined the reliability and validity of self-reported limitations encountered in the activities of daily living (ADL) as measure of functional performance, for Turkish, Moroccan, and indigenous Dutch elderly in the Netherlands. Methods: We obtained data on self-reported

  8. Muscle strength as a predictor of onset of ADL dependence in people aged 75 years

    DEFF Research Database (Denmark)

    Rantanen, Taina; Avlund, Kirsten; Suominen, Harri

    2002-01-01

    . For each muscle group tested, three equal groups were formed for men and women separately based on distributions of results. Those who reported being unable or needing help for eating, dressing, bathing, toileting, walking indoors or transferring from a bed or a chair were rated as ADL dependent...

  9. Hospital Readmission among Older Adults Who Return Home with Unmet Need for ADL Disability

    Science.gov (United States)

    DePalma, Glen; Xu, Huiping; Covinsky, Kenneth E.; Craig, Bruce A.; Stallard, Eric; Thomas, Joseph, III.; Sands, Laura P.

    2013-01-01

    Purpose: This study determined whether returning to the community from a recent hospitalization with unmet activities of daily living (ADL) need was associated with probability of readmission. Methods: A total of 584 respondents to the 1994, 1999, and/or 2004 National Long-Term Care Surveys (NLTCS) who were hospitalized within 90 days prior to the…

  10. Disability in the individual ADL, IADL, and mobility among older adults : A prospective cohort study

    NARCIS (Netherlands)

    Bleijenberg, Nienke; Zuithoff, NPA; Smith, A. K.; de Wit, N. J.; Schuurmans, M. J.

    2017-01-01

    Objectives: To examine the risk of disability in 15 individual ADL, IADL, and mobility in older adults by age; and to assess the association of multimorbidity, gender, and education with disability. Design & Setting: A prospective cohort study. The sample included 805 community-dwelling older people

  11. QMG and MG-ADL correlations: Study of eculizumab treatment of myasthenia gravis.

    Science.gov (United States)

    Howard, James F; Freimer, Miriam; O'Brien, Fanny; Wang, Jing Jing; Collins, Stephen R; Kissel, John T

    2017-08-01

    A phase 2 study of eculizumab for treating myasthenia gravis (MG) used the quantitative myasthenia gravis score (QMG) and myasthenia gravis activities of daily living profile (MG-ADL) to evaluate baseline disease severity and treatment response. Correlations were then analyzed between these assessments. Patients were given eculizumab or placebo during the first 16-week treatment period of the crossover study, with treatment assignments reversed for the second treatment period following a 5-week washout. QMG and MG-ADL scores at baseline and endpoint of each treatment period generated correlation coefficients for baseline status and treatment response during eculizumab therapy. Correlation strength between QMG and MG-ADL scores was higher for treatment response (R = 0.726; 95% confidence interval, 0.264-0.907; P = 0.0036) than for assessing baseline disease status (R = 0.552; 95% confidence interval, -0.022-0.839; P = 0.0495). MG-ADL may be more sensitive for assessing treatment response than point-in-time disease status. Muscle Nerve 56: 328-330, 2017. © 2016 Wiley Periodicals, Inc.

  12. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    -report and performance-based assessment of ADL offer distinct but complementary information about ability. The present study, therefore, investigated the applicability of a performance-based measure of ADL ability, the Assessment of Motor and Process Skills (AMPS), among 50 women with chronic widespread pain....... The investigated psychometric properties of the AMPS included discrimination between a sample of healthy women and those with chronic widespread pain, as well as stability when no intervention was provided and sensitivity to change following intervention. Data were obtained based on a repeated measures design...... performing AMPS evaluations twice pre- and twice post-rehabilitation. Results indicated that the ADL motor ability measures of the participants were significantly lower than those of healthy women of same age, the ADL motor and ADL process ability measures remained stable when no intervention was provided...

  13. Clinical characteristics with an impact on ADL functions of PD patients with cognitive impairment indicative of dementia.

    Directory of Open Access Journals (Sweden)

    Inga Liepelt-Scarfone

    Full Text Available BACKGROUND: Dementia in Parkinson's disease (PD is defined as cognitive decline severe enough to affect activities of daily living function (ADL. The aim of our exploratory study was to compare two groups of PD patients. Both groups had cognitive deficits severe enough to justify diagnosis of dementia, but they differed according to caregivers' rating on ADL dysfunction. Parameters which differed between the two groups were interpreted to affect the caregivers' perception of ADL dysfunction in PD patients with cognitive impairment indicative of Parkinson's disease dementia. METHODOLOGY/PRINCIPAL FINDINGS: Thirty of 131 Parkinson's disease patients fulfilled the Movement Disorders Society Task Force - recommended, cognitive Level-I-criteria for dementia. According to standardized caregiver ratings, volunteers were grouped into 18 patients with (ADL- and 12 without instrumental activities of daily living dysfunction (ADL+. Caregiver activities of daily living function ratings closely correlated with self-estimates of patients and those of physician (p<0.001. ADL- patients performed worse on tests assessing visual-construction (p<0.05 and attention (p=0.03 than ADL+ patients. Moreover, the postural instability and gait disorder subtype was more frequent in ADL- patients (p=0.009. ADL- patients tended to have more communication problems (p=0.05, more anxiety (p=0.05 and showed a tendency to be treated more often with neuroleptics (p=0.049 than ADL+. CONCLUSIONS/SIGNIFICANCE: Results indicate that worse attention, visual-construction abilities, the postural instability and gait disorder subtype, communication problems, medication and presence of anxiety are related to activities of daily living dysfunctions in Parkinson's disease patients with cognitive decline indicative of dementia. Our data suggests that not only cognitive factors but also non-cognitive factors seem to be linked to the diagnosis of Parkinson's disease dementia associated with

  14. Bridging a Survey Redesign Using Multiple Imputation: An Application to the 2014 CPS ASEC

    Directory of Open Access Journals (Sweden)

    Rothbaum Jonathan

    2017-03-01

    Full Text Available The Current Population Survey Annual Social and Economic Supplement (CPS ASEC serves as the data source for official income, poverty, and inequality statistics in the United States. In 2014, the CPS ASEC questionnaire was redesigned to improve data quality and to reduce misreporting, item nonresponse, and errors resulting from respondent fatigue. The sample was split into two groups, with nearly 70% receiving the traditional instrument and 30% receiving the redesigned instrument. Due to the relatively small redesign sample, analyses of changes in income and poverty between this and future years may lack sufficient power, especially for subgroups. The traditional sample is treated as if the responses were missing for income sources targeted by the redesign, and multiple imputation is used to generate plausible responses. A flexible imputation technique is used to place individuals into strata along two dimensions: 1 their probability of income recipiency and 2 their expected income conditional on recipiency for each income source. By matching on these two dimensions, this approach combines the ideas of propensity score matching and predictive means matching. In this article, this approach is implemented, the matching models are evaluated using diagnostics, and the results are analyzed.

  15. Differences between questionnaire- and interview-based measures of activities of daily living (ADL) ability and their association with observed ADL ability in women with rheumatoid arthritis, knee osteoarthritis, and fibromyalgia

    DEFF Research Database (Denmark)

    Wæhrens, E E; Bliddal, H; Danneskiold-Samsøe, B

    2012-01-01

    Although self-report based on questionnaire is the common method to obtain information about activities of daily living (ADL) ability in rheumatic diseases, little is known about the relationship between measures of ADL ability based on questionnaire, interview, and observation. The present study...... examined whether measures of self-reported ADL ability based on questionnaire and interview yielded different results, determined whether the magnitude of the difference varied among women with rheumatoid arthritis (RA), knee osteoarthritis (OA), and fibromyalgia (FM), and investigated the relationships...

  16. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    Science.gov (United States)

    Donkervoort, Mireille; Dekker, Joost; Deelman, Betto

    2006-12-01

    To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. Prospective cohort study. Rehabilitation centres and nursing homes. One hundred and eight left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. ADL-observations, Barthel ADL Index, Apraxia Test, Motricity Index. During the study period of 20 weeks, patients showed small improvements in apraxia (standardized mean differences of 0.19 and 0.33) and medium-sized improvements in ADL functioning (standardized mean differences from 0.37 to 0.61). About 88% of the patients were still apraxic at week 20. Less improvement in apraxia was observed in initially less severe apraxic patients. Less improvement in ADL functioning was found to be associated with more severe apraxia, a more independent initial ADL score, higher age, impaired motor functioning and longer time between stroke and first assessment. Apraxia in stroke patients is a persistent disorder, which has an adverse influence on ADL recovery.

  17. Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL among Lymphedema Patients in Leogane, Haiti.

    Directory of Open Access Journals (Sweden)

    Katherine E Mues

    Full Text Available Episodes of acute adenolymphangitis (ADL are often the first clinical sign of lymphatic filariasis (LF. They are often accompanied by swelling of the affected limb, inflammation, fever, and general malaise and lead to the progression of lymphedema. Although ADL episodes have been studied for a century or more, questions still remain as to their etiology. We quantified antibody levels to pathogens that potentially contribute to ADL episodes during and after an episode among lymphedema patients in Léogâne, Haiti. We estimated the proportion of ADL episodes hypothesized to be attributed to specific pathogens.We measured antibody levels to specific pathogens during and following an ADL episode among 41 lymphedema patients enrolled in a cohort study in Léogâne, Haiti. We calculated the absolute and relative changes in antibody levels between the ADL and convalescent time points. We calculated the proportion of episodes that demonstrated a two-fold increase in antibody level for several bacterial, fungal, and filarial pathogens.Our results showed the greatest proportion of two-fold changes in antibody levels for the carbohydrate antigen Streptococcus group A, followed by IgG2 responses to a soluble filarial antigen (BpG2, Streptococcal Pyrogenic Exotoxin B, and an antigen for the fungal pathogen Candida. When comparing the median antibody level during the ADL episode to the median antibody level at the convalescent time point, only the antigens for Pseudomonas species (P-value = 0.0351 and Streptolysin O (P-value = 0.0074 showed a significant result.Although our results are limited by the lack of a control group and few antibody responses, they provide some evidence for infection with Streptococcus A as a potential contributing factor to ADL episodes. Our results add to the current evidence and illustrate the importance of determining the causal role of bacterial and fungal pathogens and immunological antifilarial response in ADL episodes.

  18. ADL: a graphical design language for real time parallel applications

    NARCIS (Netherlands)

    M.R. van Steen; T. Vogel; A. ten Dam

    1993-01-01

    textabstractDesigning parallel applications is generally experienced as a tedious and difficult task, especially when hard real-time performance requirements have to be met. This paper discusses on-going work concerning the construction of a Design Entry System which supports the design phase of

  19. Security analysis of cyber-physical system

    Science.gov (United States)

    Li, Bo; Zhang, Lichen

    2017-05-01

    In recent years, Cyber-Physical System (CPS) has become an important research direction of academic circles and scientific and technological circles at home and abroad, is considered to be following the third wave of world information technology after the computer, the Internet. PS is a multi-dimensional, heterogeneous, deep integration of open systems, Involving the computer, communication, control and other disciplines of knowledge. As the various disciplines in the research theory and methods are significantly different, so the application of CPS has brought great challenges. This paper introduces the definition and characteristics of CPS, analyzes the current situation of CPS, analyzes the security threats faced by CPS, and gives the security solution for security threats. It also discusses CPS-specific security technology, to promote the healthy development of CPS in information security.

  20. Advancements in Distributed Learning (ADL) Environment in Support of Transformation

    Science.gov (United States)

    2017-01-01

    Architecture TO Technical Order ToR Terms of Reference TR Technical Report US/USA United States of America xAMP x=cross platform, Apache...The agenda consisted of review, discussion, and approval of the Technical Activity Plan (TAP) and the Terms of Reference ( ToR ) for the proposed HFM... Download and complete courses on mobile device (tablets and phones); • Course completions synchronized with JKO desk-top system for tracking and

  1. Interaction of valleys and circulation patterns (CPs on spatial precipitation patterns in southern Germany

    Directory of Open Access Journals (Sweden)

    M. Liu

    2013-11-01

    Full Text Available Topography exerts influence on the spatial precipitation distribution over different scales, known typically at the large scale as the orographic effect, and at the small scale as the wind-drift rainfall (WDR effect. At the intermediate scale (1~10 km, which is characterized by secondary mountain valleys, topography also demonstrates some effect on the precipitation pattern. This paper investigates such intermediate-scale topographic effects on precipitation patterns, focusing on narrow-steep valleys in the complex terrain of southern Germany, based on the daily observations over a 48 yr period (1960~2007 from a high-density rain-gauge network covering two sub-areas, Baden-Wuerttemberg (BW and Bavaria (BY. Precipitation data at the valley and non-valley stations are compared under consideration of the daily general circulation patterns (CPs classified by a fuzzy rule-based algorithm. Scatter plots of precipitation against elevation demonstrate a different behavior of valley stations comparing to non-valley stations. A detailed study of the precipitation time series for selected station triplets, each consisting of a valley station, a mountain station and an open station have been investigated by statistical analysis with the Kolmogorov–Smirnov (KS test supplemented by the One-way analysis of variance (One-way ANOVA and a graphical comparison of the mean precipitation amounts. The results show an interaction of valley orientation and the direction of the CPs at the intermediate scale, i.e. when the valley is shielded from the CP which carries the precipitation, the precipitation amount within the valley is comparable to that on the mountain crest, and both larger than the precipitation at the open station. When the valley is open to the CP, the precipitation within the valley is similar to the open station but much less than that on the mountain. Such phenomenon where the precipitation is "blind" to the valleys at the intermediate scale

  2. Race Differences in ADL Disability Decline 1984-2004: Evidence From the National Long-Term Care Survey.

    Science.gov (United States)

    Taylor, Miles G; Lynch, Scott M; Ureña, Stephanie

    2018-02-01

    Disability declined in lower levels of impairment during the late 20th century. However, it is unclear whether ADL disability also declined, or whether it did so across race. In this study, we examine cohorts entering later life between 1984 and 1999, by race, to understand changing ADL disability. We used latent class methods to model trajectories of ADL disability and subsequent mortality in the National Long-Term Care Survey among cohorts entering older adulthood (ages 65-69) between 1984 and 1999. We examined patterns by race, focusing on chronic condition profiles. White cohorts experienced consistent declines in ADL disability but Blacks saw little improvement with some evidence for increased disability. Stroke, diabetes, and heart attack were predominant in predicting disability among Blacks. Declining disability trends were only observed consistently among Whites, suggesting previous and future disability trends and their underlying causes should be examined by race.

  3. Model-based Development of Safety-critical Functions and ISO 26262 Work Products using modified EAST-ADL

    Directory of Open Access Journals (Sweden)

    Bülent Sari

    2017-07-01

    Full Text Available Safety is becoming more and more important with the ever increasing level of safety related E/E Systems built into the cars. Increasing functionality of vehicle systems through electrification of power train, in future even more by autonomous driving, leads to complexity in designing system, software and safety architecture. ISO 26262 aims to reduce the complexity and to approve the traceability of the different safety activities. This paper presents an approach about model-based development of system, software and safety architecture using Electronics Architecture and Software Technology – Architecture Description Language (EAST-ADL, being in line with the relevant standard ISO 26262. In particular, we briefly discuss how the main safety related activities, such as hazard analysis and risk assessment, developing functional and technical safety concepts and performing safety analysis can be performed model-based and how the activities can be related with system and software development. The state-of-art is also provided and compared with the proposed approach.

  4. Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK.

    Science.gov (United States)

    Park, In Ho; Kim, Kyung-Hyo; Andrade, Ana Lucia; Briles, David E; McDaniel, Larry S; Nahm, Moon H

    2012-01-01

    Although virulence of Streptococcus pneumoniae is associated with its capsule, some pathogenic S. pneumoniae isolates lack capsules and are serologically nontypeable (NT). We obtained 64 isolates that were identified as NT "pneumococci" (i.e., bacteria satisfying the conventional definition but without the multilocus sequence typing [MLST]-based definition of S. pneumoniae) by the traditional criteria. All 64 were optochin sensitive and had lytA, and 63 had ply. Twelve isolates had cpsA, suggesting the presence of a conventional but defective capsular polysaccharide synthesis (cps) locus. The 52 cpsA-negative isolates could be divided into three null capsule clades (NCC) based on aliC (aliB-like ORF1), aliD (aliB-like ORF2), and our newly discovered gene, pspK, in their cps loci. pspK encodes a protein with a long alpha-helical region containing an LPxTG motif and a YPT motif known to bind human pIgR. There were nine isolates in NCC1 (pspK(+) but negative for aliC and aliD), 32 isolates in NCC2 (aliC(+) aliD(+) but negative for pspK), and 11 in NCC3 (aliD(+) but negative for aliC and pspK). Among 52 cpsA-negative isolates, 41 were identified as S. pneumoniae by MLST analysis. All NCC1 and most NCC2 isolates were S. pneumoniae, whereas all nine NCC3 and two NCC2 isolates were not S. pneumoniae. Several NCC1 and NCC2 isolates from multiple individuals had identical MLST and cps regions, showing that unencapsulated S. pneumoniae can be infectious among humans. Furthermore, NCC1 and NCC2 S. pneumoniae isolates could colonize mice as well as encapsulated S. pneumoniae, although S. pneumoniae with an artificially disrupted cps locus did not. Moreover, an NCC1 isolate with pspK deletion did not colonize mice, suggesting that pspK is critical for colonization. Thus, PspK may provide pneumococci a means of surviving in the nasopharynx without capsule. IMPORTANCE The presence of a capsule is critical for many pathogenic bacteria, including pneumococci. Reflecting the

  5. The Link between Cognitive Measures and ADLs and IADL Functioning in Mild Alzheimer's: What Has Gender Got to Do with It?

    Directory of Open Access Journals (Sweden)

    James R. Hall

    2011-01-01

    Full Text Available Objectives. To investigate the link between neurocognitive measures and various aspects of daily living (ADL and IADL in women and men with mild Alzheimer's disease (AD. Methods. Participants were 202 AD patients (91 male, 111 female with CDR global scores of ≤1. ADLs and IADLs ratings were obtained from caregivers. Cognitive domains were assessed with neuropsychological testing. Results. Memory and executive functioning were related to IADL scores. Executive functioning was linked to total ADL. Comparisons stratified on gender found attention predicted total ADL score in both men and women. Attention predicted bathing and eating ability in women only. Language predicted IADL functions in men (food preparation and women (driving. Conclusions. Associations between ADLs/IADLs and memory, learning, executive functioning, and language suggest that even in patients with mild AD, basic ADLs require complex cognitive processes. Gender differences in the domains of learning and memory area were found.

  6. Clinical characteristics with an impact on ADL functions of PD patients with cognitive impairment indicative of dementia.

    Science.gov (United States)

    Liepelt-Scarfone, Inga; Fruhmann Berger, Monika; Prakash, Deborah; Csoti, Ilona; Gräber, Susanne; Maetzler, Walter; Berg, Daniela

    2013-01-01

    Dementia in Parkinson's disease (PD) is defined as cognitive decline severe enough to affect activities of daily living function (ADL). The aim of our exploratory study was to compare two groups of PD patients. Both groups had cognitive deficits severe enough to justify diagnosis of dementia, but they differed according to caregivers' rating on ADL dysfunction. Parameters which differed between the two groups were interpreted to affect the caregivers' perception of ADL dysfunction in PD patients with cognitive impairment indicative of Parkinson's disease dementia. Thirty of 131 Parkinson's disease patients fulfilled the Movement Disorders Society Task Force - recommended, cognitive Level-I-criteria for dementia. According to standardized caregiver ratings, volunteers were grouped into 18 patients with (ADL-) and 12 without instrumental activities of daily living dysfunction (ADL+). Caregiver activities of daily living function ratings closely correlated with self-estimates of patients and those of physician (pvisual-construction (pvisual-construction abilities, the postural instability and gait disorder subtype, communication problems, medication and presence of anxiety are related to activities of daily living dysfunctions in Parkinson's disease patients with cognitive decline indicative of dementia. Our data suggests that not only cognitive factors but also non-cognitive factors seem to be linked to the diagnosis of Parkinson's disease dementia associated with significant impact on instrumental activities of daily living function. Further studies with larger sample sizes are needed to verify our results.

  7. Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale

    Directory of Open Access Journals (Sweden)

    Fabiana Carla Matos da Cunha Cintra

    Full Text Available Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32 participants were diagnosed as mild cognitive impairment (MCI patients, 33 as Alzheimer’s disease (AD patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1 and by AD (55.9, with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

  8. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    -report and performance-based assessment of ADL offer distinct but complementary information about ability. The present study, therefore, investigated the applicability of a performance-based measure of ADL ability, the Assessment of Motor and Process Skills (AMPS), among 50 women with chronic widespread pain......Functional ability, including the ability to perform activities of daily living (ADL), is considered a core outcome domain in chronic pain clinical trials and is usually assessed through generic or disease-specific self-report questionnaires. Research, however, indicates that self....... The investigated psychometric properties of the AMPS included discrimination between a sample of healthy women and those with chronic widespread pain, as well as stability when no intervention was provided and sensitivity to change following intervention. Data were obtained based on a repeated measures design...

  9. Predicting Child Protective Services (CPS) Involvement among Low-Income U.S. Families with Young Children Receiving Nutritional Assistance.

    Science.gov (United States)

    Slack, Kristen S; Font, Sarah; Maguire-Jack, Kathryn; Berger, Lawrence M

    2017-10-11

    This exploratory study examines combinations of income-tested welfare benefits and earnings, as they relate to the likelihood of child maltreatment investigations among low-income families with young children participating in a nutritional assistance program in one U.S. state (Wisconsin). Using a sample of 1065 parents who received the Special Supplemental Nutrition Assistance Program for Women, Infants, and Children (WIC) benefits in late 2010 and early 2011, we find that relying on either work in the absence of other means-tested welfare benefits, or a combination of work and welfare benefits, reduces the likelihood of CPS involvement compared to parents who rely on welfare benefits in the absence of work. Additionally, we find that housing instability increases the risk of CPS involvement in this population. The findings from this investigation may be useful to programs serving low-income families with young children, as they attempt to identify safety net resources for their clientele.

  10. Long-term declines in ADLs, IADLs, and mobility among older Medicare beneficiaries

    Directory of Open Access Journals (Sweden)

    Wolinsky Fredric D

    2011-08-01

    Full Text Available Abstract Background Most prior studies have focused on short-term (≤ 2 years functional declines. But those studies cannot address aging effects inasmuch as all participants have aged the same amount. Therefore, the authors studied the extent of long-term functional decline in older Medicare beneficiaries who were followed for varying time lengths, and the authors also identified the risk factors associated with those declines. Methods The analytic sample included 5,871 self- or proxy-respondents who had complete baseline and follow-up survey data that could be linked to their Medicare claims for 1993-2007. Functional status was assessed using activities of daily living (ADLs, instrumental ADLs (IADLs, and mobility limitations, with declines defined as the development of two of more new difficulties. Multiple logistic regression analysis was used to focus on the associations involving respondent status, health lifestyle, continuity of care, managed care status, health shocks, and terminal drop. Results The average amount of time between the first and final interviews was 8.0 years. Declines were observed for 36.6% on ADL abilities, 32.3% on IADL abilities, and 30.9% on mobility abilities. Functional decline was more likely to occur when proxy-reports were used, and the effects of baseline function on decline were reduced when proxy-reports were used. Engaging in vigorous physical activity consistently and substantially protected against functional decline, whereas obesity, cigarette smoking, and alcohol consumption were only associated with mobility declines. Post-baseline hospitalizations were the most robust predictors of functional decline, exhibiting a dose-response effect such that the greater the average annual number of hospital episodes, the greater the likelihood of functional status decline. Participants whose final interview preceded their death by one year or less had substantially greater odds of functional status decline

  11. Development of computerized procedures system for nuclear power plants

    International Nuclear Information System (INIS)

    Liu Fei; Zhang Zhijian; Peng Minjun

    2007-01-01

    In order to improve the application of operating procedures, an computerized procedures presentation system (CPS) for normal operation is developed on embedded real-time operation system VxWorks using C language. This paper introduces the composing of CPS, and the design of human-machine interface are stressed. The validation of CPS is described with the example of cold startup. The system helps operators to enhance the veracity of operation and the work load of operators will be reduced. (authors)

  12. AudioRegent: Exploiting SimpleADL and SoX for Digital Audio Delivery

    Directory of Open Access Journals (Sweden)

    Nitin Arora

    2010-06-01

    Full Text Available AudioRegent is a command-line Python script currently being used by the University of Alabama Libraries’ Digital Services to create web-deliverable MP3s from regions within archival audio files. In conjunction with a small-footprint XML file called SimpleADL and SoX, an open-source command-line audio editor, AudioRegent batch processes archival audio files, allowing for one or many user-defined regions, particular to each audio file, to be extracted with additional audio processing in a transparent manner that leaves the archival audio file unaltered. Doing so has alleviated many of the tensions of cumbersome workflows, complicated documentation, preservation concerns, and reliance on expensive closed-source GUI audio applications.

  13. The Prediction of ADL and IADL Disability Using Six Physical Indicators of Frailty: A Longitudinal Study in the Netherlands

    Science.gov (United States)

    Gobbens, Robbert J. J.; van Assen, Marcel A. L. M.

    2014-01-01

    Frailty is a predictor of disability. A proper understanding of the contribution of individual indicators of frailty in the prediction of disability is a requisite for preventive interventions. The aim of this study was to determine the predictive power of the individual physical frailty indicators: gait speed, physical activity, hand grip strength, Body Mass Index (BMI), fatigue, and balance, for ADL and IADL disability. The sample consisted of 505 community-dwelling persons (≥75 years, response rate 35.1%). Respondents first participated between November 2007 and June 2008, and a subset of all respondents participated again one year later (N = 264, 52.3% response rate). ADL and IADL disability were assessed by the Groningen Activity Restriction Scale. BMI was assessed by self-report, and the other physical frailty indicators were assessed with the TUG test (gait speed), the LAPAQ (physical activity), a hand grip strength test, the SFQ (fatigue), and the Four-test balance scale. All six physical frailty indicators were associated with ADL and IADL disability. After controlling for previous disability, sociodemographic characteristics, self-perceived lifestyle, and chronic diseases, only gait speed was predictive of both ADL and IADL disability, whereas there was a small effect of fatigue on IADL disability. Hence, these physical frailty indicators should be included in frailty assessment when predicting future disability. PMID:24782894

  14. The impact of physical performance and cognitive status on subsequent ADL disability in low-functioning older adults

    NARCIS (Netherlands)

    Kempen, GIJM; Ormel, J

    Objectives. The purpose of this study was to examine the independent contributions of physical performance and cognitive status to subsequent levels of ADL disability in low-functioning non-institutionalized older adults. Methods. A prospective cohort study included 416 women and 141 men 57 years of

  15. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    NARCIS (Netherlands)

    Donkervoort, M.; Dekker, J.; Deelman, B.

    2006-01-01

    OBJECTIVE: To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. DESIGN: Prospective cohort study. SETTING: Rehabilitation centres and nursing homes. SUBJECTS: One hundred and eight left hemisphere stroke patients with apraxia, hospitalized

  16. A client-centred ADL intervention: three-month follow-up of a randomized controlled trial

    Science.gov (United States)

    Bertilsson, Ann-Sofie; Ranner, Maria; von Koch, Lena; Eriksson, Gunilla; Johansson, Ulla; Ytterberg, Charlotte; Tham, Kerstin

    2014-01-01

    Objective The aim was to study a client-centred activities of daily living (ADL) intervention (CADL) compared with the usual ADL intervention (UADL) in people with stroke regarding: independence in ADL, perceived participation, life satisfaction, use of home-help service, and satisfaction with training and, in their significant others, regarding: caregiver burden, life satisfaction, and informal care. Methods In this multicentre study, 16 rehabilitation units were randomly assigned to deliver CADL or UADL. The occupational therapists who provided the CADL were specifically trained. Eligible for inclusion were people with stroke treated in a stroke unit ≤3 months after stroke, dependent in ≥two ADL, not diagnosed with dementia, and able to understand instructions. Data were collected at inclusion and three months thereafter. To detect a significant difference between the groups in the Stroke Impact Scale (SIS) domain “participation”, 280 participants were required. Intention-to-treat analysis was applied. Results At three months, there was no difference in the outcomes between the CADL group (n = 129) and the UADL group (n = 151), or their significant others (n = 87/n = 93) except in the SIS domain “emotion” in favour of CADL (p = 0.04). Conclusion The CADL does not appear to bring about short-term differences in outcomes and longer follow-ups are required. PMID:24506231

  17. A client-centred ADL intervention: three-month follow-up of a randomized controlled trial.

    Science.gov (United States)

    Bertilsson, Ann-Sofie; Ranner, Maria; von Koch, Lena; Eriksson, Gunilla; Johansson, Ulla; Ytterberg, Charlotte; Guidetti, Susanne; Tham, Kerstin

    2014-09-01

    The aim was to study a client-centred activities of daily living (ADL) intervention (CADL) compared with the usual ADL intervention (UADL) in people with stroke regarding: independence in ADL, perceived participation, life satisfaction, use of home-help service, and satisfaction with training and, in their significant others, regarding: caregiver burden, life satisfaction, and informal care. In this multicentre study, 16 rehabilitation units were randomly assigned to deliver CADL or UADL. The occupational therapists who provided the CADL were specifically trained. Eligible for inclusion were people with stroke treated in a stroke unit ≤3 months after stroke, dependent in ≥two ADL, not diagnosed with dementia, and able to understand instructions. Data were collected at inclusion and three months thereafter. To detect a significant difference between the groups in the Stroke Impact Scale (SIS) domain "participation", 280 participants were required. Intention-to-treat analysis was applied. At three months, there was no difference in the outcomes between the CADL group (n = 129) and the UADL group (n = 151), or their significant others (n = 87/n = 93) except in the SIS domain "emotion" in favour of CADL (p = 0.04). The CADL does not appear to bring about short-term differences in outcomes and longer follow-ups are required.

  18. Older Asian Americans and Pacific Islanders with Activities of Daily Living (ADL) limitations: immigration and other factors associated with institutionalization.

    Science.gov (United States)

    Fuller-Thomson, Esme; Chi, Monica

    2012-09-07

    This study determined the national prevalence and profile of Asian Americans with Activities of Daily Living (ADL) limitations and identified factors associated with institutionalization. Data were obtained from 2006 American Community Survey, which replaced the long-form of the US Census. The data are nationally representative of both institutionalized and community-dwelling older adults. Respondents were Vietnamese (n = 203), Korean (n = 131), Japanese (n = 193), Filipino (n = 309), Asian Indian (n = 169), Chinese (n = 404), Hawaiian/Pacific Islander (n = 54), and non-Hispanic whites (n = 55,040) aged 55 and over who all had ADL limitations. The prevalence of institutionalized among those with ADL limitations varies substantially from 4.7% of Asian Indians to 18.8% of Korean Americans with ADL limitations. Every AAPI group had a lower prevalence of institutionalization than disabled Non-Hispanic whites older adults (23.8%) (p institutionalization than non-Hispanic whites (OR = 0.29, 0.31, 0.58, 0.51, 0.70, respectively). When the sample was restricted to AAPIs, the odds of institutionalization were higher among those who were older, unmarried, cognitively impaired and those who spoke English at home. This variation suggests that aggregating data across the AAPI groups obscures meaningful differences among these subpopulations and substantial inter-group differences may have important implications in the long-term care setting.

  19. Biochemical Characterization of CPS-1, a Subclass B3 Metallo-β-Lactamase from a Chryseobacterium piscium Soil Isolate

    DEFF Research Database (Denmark)

    Gudeta, Dereje Dadi; Pollini, Simona; Docquier, Jean-Denis

    2016-01-01

    CPS-1 is a subclass B3 metallo-β-lactamase from a Chryseobacterium piscium isolated from soil, showing 68 % amino acid identity to GOB-1 enzyme. CPS-1 was overproduced in Escherichia coli Rosetta (DE3), purified by chromatography and biochemically characterized. This enzyme exhibits a broad spect...... spectrum substrate profile including penicillins, cephalosporins and carbapenems, which overall resembles those of L1, GOB-1 and acquired subclass B3 enzymes AIM-1 and SMB-1....

  20. Software Engineering Issues for Cyber-Physical Systems

    DEFF Research Database (Denmark)

    Al-Jaroodi, Jameela; Mohamed, Nader; Jawhar, Imad

    2016-01-01

    is not a trivial task. This paper provides an overview discussion of software engineering issues related to the analysis, design, development, verification and validation, and quality assurance of CPS software. Some of these issues are related to the nature/type of CPS while others are related to the complexity......Cyber-Physical Systems (CPS) provide many smart features for enhancing physical processes. These systems are designed with a set of distributed hardware, software, and network components that are embedded in physical systems and environments or attached to humans. Together they function seamlessly...... to offer specific functionalities or features that help enhance human lives, operations or environments. While different CPS components play important roles in a successful CPS development, the software plays the most important role among them. Acquiring and using high quality CPS components is the first...

  1. Mobile Computerized Procedure System for the Improved Situation Awareness among Field Workers and Main Control Room Operators

    International Nuclear Information System (INIS)

    Lee, Sungjin; Seong, Nokyu; Jung, Yeonsub

    2013-01-01

    This paper explains the technical issues of the mobile CPS (m-CPS) in the conceptual development stage. The proposed m-CPS can be developed with many recent technologies in the various industry fields based on CRI CPS. Performance and stability of CRI CPS have been tested several times until now. It is expected that more human errors can be reduced by the m-CPS through improved situation awareness and human performance tools for local workers and MCR operators. Some considerations as well as mentioned ones will be reflected in the m-CPS development. Human errors can occur during the test and maintenance of the generator, safety injection system and reactor coolant inventory in nuclear power plants (NPPs). Most of human errors have been occurred by the omission of the prevention techniques such as the self-check, the peer-check, the concurrent verification and etc. Another important reason is the insufficient information sharing among main control room (MCR) operators and field workers. Various field service automation tools have been developed with recent information technology in many countries. APR1400 computerized procedure system (CPS) has been developed for the MCR operators of Shin-Kori 3 and 4 units. Especially, the concurrent verification support design is applied in the construction project of Shin-Hanul 1 and 2 CPS. KHNP central research institute (CRI) expects that the extended application of CPS including the field activity, that is a kind of mobile CPS, can enhance the reduction of human errors

  2. Mac protocols for cyber-physical systems

    CERN Document Server

    Xia, Feng

    2015-01-01

    This book provides a literature review of various wireless MAC protocols and techniques for achieving real-time and reliable communications in the context of cyber-physical systems (CPS). The evaluation analysis of IEEE 802.15.4 for CPS therein will give insights into configuration and optimization of critical design parameters of MAC protocols. In addition, this book also presents the design and evaluation of an adaptive MAC protocol for medical CPS, which exemplifies how to facilitate real-time and reliable communications in CPS by exploiting IEEE 802.15.4 based MAC protocols. This book wil

  3. A Method for Cyber-Physical System Behavior Modeling and Safety Verification Based on Extended Hybrid System Description Language

    Directory of Open Access Journals (Sweden)

    Tuo Ming Fu

    2016-01-01

    Full Text Available The safety of Cyber-physical system(CPS is up to its behavior, and it is a key property for CPS to be applied in critical application fields. A method for CPS behavior modeling and safety verification is put forward in this paper. The behavior model of CPS is described by extended hybrid system description language(EHYSDEL. The formal definition of hybrid program(HP is given, and the behavior model is transformed to HP based on the definition. The safety of CPS is verified by inputting the HP to KeYmarea. The advantage of the approach is that it models CPS intuitively and verify it’s safety strictly avoiding the state space explosion

  4. Security and privacy in cyber-physical systems foundations, principles, and applications

    CERN Document Server

    Song, Houbing; Jeschke, Sabina

    2017-01-01

    Written by a team of experts at the forefront of the cyber-physical systems (CPS) revolution, this book provides an in-depth look at security and privacy, two of the most critical challenges facing both the CPS research and development community and ICT professionals. It explores, in depth, the key technical, social, and legal issues at stake, and it provides readers with the information they need to advance research and development in this exciting area. Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability far in excess of what today's simple embedded systems can provide. Just as the Internet revolutionized the way we interact with information, CPS technology has already begun to transform the way people interact with engineered systems. In the years ahead, smart CPS will drive innovat...

  5. High-energy coordination polymers (CPs) exhibiting good catalytic effect on the thermal decomposition of ammonium dinitramide

    Science.gov (United States)

    Li, Xin; Han, Jing; Zhang, Sheng; Zhai, Lianjie; Wang, Bozhou; Yang, Qi; Wei, Qing; Xie, Gang; Chen, Sanping; Gao, Shengli

    2017-09-01

    High-energy coordination polymers (CPs) not only exhibit good energetic performances but also have a good catalytic effect on the thermal decomposition of energetic materials. In this contribution, two high-energy CPs Cu2(DNBT)2(CH3OH)(H2O)3·3H2O (1) and [Cu3(DDT)2(H2O)2]n (2) (H2DNBT = 3,3‧-dinitro-5,5‧-bis(1H-1,2,4-triazole and H3DDT = 4,5-bis(1H-tetrazol-5-yl)-2H-1,2,3-triazole) were synthesized and structurally characterized. Furthermore, 1 was thermos-dehydrated to produce Cu2(DNBT)2(CH3OH)(H2O)3 (1a). The thermal decomposition kinetics of 1, 1a and 2 were studied by Kissinger's method and Ozawa's method. Thermal analyses and sensitivity tests show that all compounds exhibit high thermal stability and low sensitivity for external stimuli. Meanwhile, all compounds have large positive enthalpy of formation, which are calculated as being (1067.67 ± 2.62) kJ mol-1 (1), (1464.12 ± 3.12) kJ mol-1 (1a) and (3877.82 ± 2.75) kJ mol-1 (2), respectively. The catalytic effects of 1a and 2 on the thermal decomposition of ammonium dinitramide (ADN) were also investigated.

  6. How to Maintain Computerized Procedure System in the same Version

    International Nuclear Information System (INIS)

    Jung, Yeon Sub

    2016-01-01

    CPS(Computerized Procedure System) has been introduced in advanced nuclear power plant worldwide. Korean CPS complies with this trend. It has been applied to Shinkori3,4 and all their successors including BNPP1,2,3,4. CPS is designed by KHNP CRI, and developed by Westinghouse or Doosan. Initial design has been improved by reflecting operator experience, human factor V and V, and advanced engineering method. Design improvement makes CPS differ from plant to plant. For example CPS in Shinhanul cannot interpret CP(Computerized Procedure) of ShinKori3, 4. Different CPS makes it difficult to utilize CP and train operators. Therefore it is important to keep CPS in single version. Note that typical text editors in the office are kept in single version. On the other hand, plant monitoring systems in main control room are actually different. Because CPS is positioned between text editor and monitoring system, goal to maintain CPS in single version is not an easy task. From Shinkori3,4, lots of improvements are achieved in CPS. This improvement surely makes operation easy and will not introduce human errors. Side effect of improvement is that PXS and CPS ES may not be compatible among nuclear power plants. So the side effect should be avoided by minimizing change of XML. Initial XML had been developed for Shinkori3,4. The XML has been modified slightly for Shinhanul1,2. PXS and CPS ES are being developed for the same version for all nuclear power plants of APR1400

  7. Associations between results of post-stroke NDT-Bobath rehabilitation in gait parameters, ADL and hand functions.

    Science.gov (United States)

    Mikołajewska, Emilia

    2013-01-01

    In patients after a stroke there are variable disorders. These patients often need rehabilitation in more than one area beceause of multiple limitations of the ability to perform everyday activities. The aim of the study was to assess correlations - statistical relationships between observed gait parameters, ADL and hand functions - results of rehabilitation of patients after ischaemic stroke according to the NDTBobath method for adults. The investigated group consisted of 60 patients after ischaemic stroke, who participated in the rehabilitation programme. 10 sessions of the NDT-Bobath therapy were provided in 2 weeks (10 days of the therapy). The calculation of correlations was made based on changes of parameters: Bobath Scale (to assess hand functions), Barthel Index (to assess ADL), gait velocity, cadence and stride lenght. Measurements were performed in every patient twice: on admission (before the therapy) and after last session of the therapy to assess rehabilitation effects. The main statistically relevant corellations observed in the study were as follows: in the whole group of patients: poor and moderate (negative) correlation between changes of gait parameters and Bobath Scale and Barthel Index, moderate and severe (negative) correlation between changes of gait parameters and Bobath Scale and Barthel Index in the group of women, correlation between changes in Bobath Scale and Barthel Index in the group of patients with left side of paresis, (negative) correlation between changes of gait parameters and Bobath Scale in group of patients younger than 68 years, moderate, high and very high correlations between changes in gait parameters in groups of women, men, younger than 68 years and older than 68 years. There have been observed statistically significant and favourable changes in the health status of patients, described by gait parameters, changes in hand functions and ADL. Based on the presented correlations there is an assumption that it is hard to

  8. Older Asian Americans and Pacific Islanders with Activities of Daily Living (ADL Limitations: Immigration and Other Factors Associated with Institutionalization

    Directory of Open Access Journals (Sweden)

    Esme Fuller-Thomson

    2012-09-01

    Full Text Available This study determined the national prevalence and profile of Asian Americans with Activities of Daily Living (ADL limitations and identified factors associated with institutionalization. Data were obtained from 2006 American Community Survey, which replaced the long-form of the US Census. The data are nationally representative of both institutionalized and community-dwelling older adults. Respondents were Vietnamese (n = 203, Korean (n = 131, Japanese (n = 193, Filipino (n = 309, Asian Indian (n = 169, Chinese (n = 404, Hawaiian/Pacific Islander (n = 54, and non-Hispanic whites (n = 55,040 aged 55 and over who all had ADL limitations. The prevalence of institutionalized among those with ADL limitations varies substantially from 4.7% of Asian Indians to 18.8% of Korean Americans with ADL limitations. Every AAPI group had a lower prevalence of institutionalization than disabled Non-Hispanic whites older adults (23.8% (p < 0.001. After adjustment for socio-demographic characteristics, Asian Indians, Vietnamese, Japanese, Filipino, and Chinese had significantly lower odds of institutionalization than non-Hispanic whites (OR = 0.29, 0.31, 0.58, 0.51, 0.70, respectively. When the sample was restricted to AAPIs, the odds of institutionalization were higher among those who were older, unmarried, cognitively impaired and those who spoke English at home. This variation suggests that aggregating data across the AAPI groups obscures meaningful differences among these subpopulations and substantial inter-group differences may have important implications in the long-term care setting.

  9. Dispersion of Short- and Medium-Chain Chlorinated Paraffins (CPs) from a CP Production Plant to the Surrounding Surface Soils and Coniferous Leaves.

    Science.gov (United States)

    Xu, Jiazhi; Gao, Yuan; Zhang, Haijun; Zhan, Faqiang; Chen, Jiping

    2016-12-06

    Chlorinated paraffin (CP) production is one important emission source for short- and medium-chain CPs (SCCPs and MCCPs) in the environment. In this study, 48 CP congener groups were measured in the surface soils and coniferous leaves collected from the inner and surrounding environment of a CP production plant that has been in operation for more than 30 years to investigate the dispersion and deposition behavior of SCCPs and MCCPs. The average concentrations of the sum of SCCPs and MCCPs in the in-plant coniferous leaves and surface soils were 4548.7 ng g -1 dry weight (dw) and 3481.8 ng g -1 dw, which were 2-fold and 10-fold higher than those in the surrounding environment, respectively. The Gaussian air pollution model explained the spatial distribution of CPs in the coniferous leaves, whereas the dispersion of CPs to the surrounding surface soils fits the Boltzmann equation well. Significant fractionation effect was observed for the atmospheric dispersion of CPs from the production plant. CP congener groups with higher octanol-air partitioning coefficients (K OA ) were more predominant in the in-plant environment, whereas the ones with lower K OA values had the elevated proportion in the surrounding environment. A radius of approximately 4 km from the CP production plant was influenced by the atmospheric dispersion and deposition of CPs.

  10. Crystal structures of YwqE from Bacillus subtilis and CpsB from Streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases.

    Science.gov (United States)

    Kim, Hyoun Sook; Lee, Sang Jae; Yoon, Hye Jin; An, Doo Ri; Kim, Do Jin; Kim, Soon-Jong; Suh, Se Won

    2011-09-01

    Unique metal-dependent protein tyrosine phosphatases that belong to the polymerase and histindinol phosphatase (PHP) family are present in Gram-positive bacteria. They are distinct from the Cys-based, low-molecular-weight phosphotyrosine protein phosphatases (LMPTPs). Two representative members of the PHP family tyrosine phosphatases are YwqE from Bacillus subtilis and CpsB from Streptococcus pneumoniae. YwqE is involved in polysaccharide biosynthesis, bacterial DNA metabolism, and DNA damage response in B. subtilis. CpsB regulates capsular polysaccharide biosynthesis via tyrosine dephosphorylation of CpsD, its cognate tyrosine kinase, in S. pneumoniae. To gain insights into the active site and possible conformational changes of the metal-dependent tyrosine phosphatases from Gram-positive bacteria, we have determined the crystal structures of B. subtilis YwqE (in both the apo form and the phosphate-bound form) and S. pneumoniae CpsB (in the sulfate-bound form). Comparisons of the three structures reveal conformational plasticity of two active site loops. Furthermore, in both structures of the phosphate-bound YwqE and the sulfate-bound CpsB, the phosphate (or sulfate) ion is bound to a cluster of three metal ions in the active site, thus providing insight into the pre-catalytic state. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. THE EFFECT OF SOIL CONDITIONERS ON CELLULOSE, HEMICELLULOSE, AND THE ADL FIBRE FRACTION CONCENTRATION IN DACTYLIS GLOMERATA AND LOLIUM PERENNE

    Directory of Open Access Journals (Sweden)

    Milena Truba

    2017-01-01

    Full Text Available Replicated three times, the research was conducted in the experimental field between 2011 and 2014. Three soil conditioners with the following trade names: UGmax, Eko-Użyźniacz, and Humus Active Papka were used in the experiment, separately or together with NPK fertilisers. They were all used on plots sown with two species of grass, Dactylis glomerata of the Bora variety and Lolium perenne of the Info variety. The plant material from both grass species was tested for the concentration of ADL fraction (% DM, cellulose (% DM, and hemicellulose (% DM. It was found that the concentration of cellulose, hemicelluloses, and the ADL fraction was significantly higher in the biomass of Dactylis glomerata than in the biomass of Lolium perenne. The grass from the plot with the UGmax soil conditioner applied had the highest amount of cellulose and hemicellulose. The lowest amount of those organic compounds was found in the grass treated with UGmax together with mineral fertilisers and in plants treated with Humus Active, together with mineral fertilisers. However, the fertilisers and conditioners did not increase the ADL content in both grass species.

  12. Estimating the number of components and detecting outliers using Angle Distribution of Loading Subspaces (ADLS) in PCA analysis.

    Science.gov (United States)

    Liu, Y J; Tran, T; Postma, G; Buydens, L M C; Jansen, J

    2018-08-22

    Principal Component Analysis (PCA) is widely used in analytical chemistry, to reduce the dimensionality of a multivariate data set in a few Principal Components (PCs) that summarize the predominant patterns in the data. An accurate estimate of the number of PCs is indispensable to provide meaningful interpretations and extract useful information. We show how existing estimates for the number of PCs may fall short for datasets with considerable coherence, noise or outlier presence. We present here how Angle Distribution of the Loading Subspaces (ADLS) can be used to estimate the number of PCs based on the variability of loading subspace across bootstrap resamples. Based on comprehensive comparisons with other well-known methods applied on simulated dataset, we show that ADLS (1) may quantify the stability of a PCA model with several numbers of PCs simultaneously; (2) better estimate the appropriate number of PCs when compared with the cross-validation and scree plot methods, specifically for coherent data, and (3) facilitate integrated outlier detection, which we introduce in this manuscript. We, in addition, demonstrate how the analysis of different types of real-life spectroscopic datasets may benefit from these advantages of ADLS. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  13. Item-level psychometrics of the ADL instrument of the Korean National Survey on persons with physical disabilities.

    Science.gov (United States)

    Hong, Ickpyo; Lee, Mi Jung; Kim, Moon Young; Park, Hae Yean

    2017-10-01

    The aim of this study is to investigate the psychometrics of the 12 items of an instrument assessing activities of daily living (ADL) using an item response theory model. A total of 648 adults with physical disabilities and having difficulties in ADLs were retrieved from the 2014 Korean National Survey on People with Disabilities. The psychometric testing included factor analysis, internal consistency, precision, and differential item functioning (DIF) across categories including sex, older age, marital status, and physical impairment area. The sample had a mean age of 69.7 years old (SD = 13.7). The majority of the sample had lower extremity impairments (62.0%) and had at least 2.1 chronic conditions. The instrument demonstrated unidimensional construct and good internal consistency (Cronbach's alpha = 0.95). The instrument precisely estimated person measures within a wide range of theta values (-2.22 logits  5.0%). Our findings indicate that the dressing item would need to be modified to improve its psychometrics. Overall, the ADL instrument demonstrates good psychometrics, and thus, it may be used as a standardized instrument for measuring disability in rehabilitation contexts. However, the findings are limited to adults with physical disabilities. Future studies should replicate psychometric testing for survey respondents with other disorders and for children.

  14. The Hamlet design entry system: an overview of ADL and its environment

    NARCIS (Netherlands)

    M.R. van Steen; A. ten Dam; T. Vogel

    1994-01-01

    textabstractExploiting parallelism for industrial real-time applications has not received much attention compared to scientific applications. The available real-time design methods do not adequately address the issue of parallelism, resulting still in a strong need for low-level tools such as

  15. The Effects of the Green House Nursing Home Model on ADL Function Trajectory: A Retrospective Longitudinal Study

    Science.gov (United States)

    YOON, Ju Young; BROWN, Roger L.; BOWERS, Barbara J.; SHARKEY, Siobhan S.; HORN, Susan D.

    2015-01-01

    Background Growing attention in the past few decades has focused on improving care quality and quality of life for nursing home residents. Many traditional nursing homes have attempted to transform themselves to become more homelike emphasizing individualized care. This trend is referred to as nursing home culture change in the U.S. A promising culture change nursing home model, the Green House (GH) nursing home model, has shown positive psychological outcomes. However, little is known about whether the GH nursing home model has positive effects on physical function compared to traditional nursing homes. Objectives To examine the longitudinal effects of the GH nursing home model by comparing change patterns of ADL function over time between GH home residents and traditional nursing home residents. Design A retrospective longitudinal study. Settings Four GH organizations (nine GH units and four traditional units). Participants A total of 242 residents (93 GH residents and 149 traditional home residents) who had stayed in the nursing home at least six months from admission. Methods The outcome was ADL function, and the main independent variable was the facility type in which the resident stayed: a GH or traditional unit. Age, gender, comorbidity score, cognitive function, and depressive symptoms at baseline were controlled. All of these measures were from a minimum dataset. Growth curve modeling and growth mixture modeling were employed in this study for longitudinal analyses. Results The mean ADL function showed deterioration over time, and the rates of deterioration between GH and traditional home residents were not different over time. Four different ADL function trajectories were identified for 18 months, but there was no statistical difference in the likelihood of being in one of the four trajectory classes between the two groups. Conclusions Although GH nursing homes are considered to represent an innovative model changing the nursing home environment into more

  16. Does physical exercise improve ADL capacities in people over 65 years with moderate or severe dementia hospitalized in an acute psychiatric setting? A multisite randomized clinical trial.

    Science.gov (United States)

    Bürge, Elisabeth; Berchtold, André; Maupetit, Christine; Bourquin, Nathalie M-P; von Gunten, Armin; Ducraux, Daniel; Zumbach, Serge; Peeters, Anne; Kuhne, Nicolas

    2017-02-01

    Several studies on the effect of physical exercise on activities of daily living (ADL) for people with dementia exist; yet, data concerning the specific context of acute psychiatric hospitals remain scant. This study measured the effect of a physical exercise program on ADL scores in patients with moderate to severe dementia hospitalized in an acute psychiatric ward. A multicenter clinical trial was conducted in five Swiss and Belgian psychiatric hospitals. Participants were randomly allocated to either an experimental group (EG) or a control group (CG). Members of the EG received 20 physical exercise sessions (strengthening, balance, and walking) over a four-week period while members of the CG participated in social interaction sessions of equivalent duration and frequency, but without physical exercise. The effect of exercise on ADL was measured by comparing scores of the Barthel Index and the Functional Independence Measure in the EG and CG before and after the intervention, and two weeks later. Hundred and sixty patients completed the program. Characteristics of participants of both groups were similar at the inception of the study. The mean ADL score of EG decreased slightly over time, whereas that of the CG significantly decreased compared to initial scores. Overall differences between groups were not significant; however, significant differences were found for mobility-related items. ADL scores in elderly with moderate to severe dementia deteriorate during acute psychiatric hospitalization. An exercise program delays the loss of mobility but does not have a significant impact on overall ADL scores.

  17. Phase Variable Expression of a Single Phage Receptor in Campylobacter jejuni NCTC12662 Influences Sensitivity Toward Several Diverse CPS-Dependent Phages

    Directory of Open Access Journals (Sweden)

    Yilmaz Emre Gencay

    2018-02-01

    Full Text Available Campylobacter jejuni NCTC12662 is sensitive to infection by many Campylobacter bacteriophages. Here we used this strain to investigate the molecular mechanism behind phage resistance development when exposed to a single phage and demonstrate how phase variable expression of one surface component influences phage sensitivity against many diverse C. jejuni phages. When C. jejuni NCTC12662 was exposed to phage F207 overnight, 25% of the bacterial cells were able to grow on a lawn of phage F207, suggesting that resistance develops at a high frequency. One resistant variant, 12662R, was further characterized and shown to be an adsorption mutant. Plaque assays using our large phage collection showed that seven out of 36 diverse capsular polysaccharide (CPS-dependent phages could not infect 12662R, whereas the remaining phages formed plaques on 12662R with reduced efficiencies. Analysis of the CPS composition of 12662R by high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR showed a diminished signal for O-methyl phosphoramidate (MeOPN, a phase variable modification of the CPS. This suggested that the majority of the 12662R population did not express this phase variable modification in the CPS, indicating that MeOPN serves as a phage receptor in NCTC12662. Whole genome analysis of 12662R showed a switch in the length of the phase variable homopolymeric G tract of gene 06810, encoding a putative MeOPN-transferase located in the CPS locus, resulting in a non-functional protein. To confirm the role of 06810 in phage resistance development of NCTC12662, a 06810 knockout mutant in NCTC12662 was constructed and analyzed by HR-MAS NMR demonstrating the absence of MeOPN in the CPS of the mutant. Plaque assays using NCTC12662Δ06810 demonstrated that seven of our CPS-dependent Campylobacter phages are dependent on the presence of MeOPN for successful infection of C. jejuni, whereas the remaining 29 phages infect independently of Me

  18. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Volume 123 Issue 7 October 2014 pp 1637-1652. Forecasting of cyclone Viyaru and Phailin by NWP-based cyclone prediction system (CPS) of IMD – an evaluation · S D Kotal S K Bhattacharya S K Roy Bhowmik P K Kundu · More Details Abstract Fulltext PDF. An objective NWP-based cyclone prediction system (CPS) was ...

  19. Reachable Sets of Hidden CPS Sensor Attacks : Analysis and Synthesis Tools

    NARCIS (Netherlands)

    Murguia, Carlos; van de Wouw, N.; Ruths, Justin; Dochain, Denis; Henrion, Didier; Peaucelle, Dimitri

    2017-01-01

    For given system dynamics, control structure, and fault/attack detection procedure, we provide mathematical tools–in terms of Linear Matrix Inequalities (LMIs)–for characterizing and minimizing the set of states that sensor attacks can induce in the system while keeping the alarm rate of the

  20. Characterization of CPs/Ca-exchanged FAU- and LTA-type zeolite nanocomposites and their selectivity for CO2 and N2 adsorption

    Science.gov (United States)

    Salehi, Samira; Anbia, Mansoor

    2017-11-01

    The objective of this study was to investigate the adsorption capacity and selectivity of CPs/Ca-exchanged FAU- and LTA-type zeolite composites for carbon dioxide (CO2), and nitrogen (N2). The adsorption isotherms of CO2 and N2 on the adsorbents were measured at 298, 323, and 348 K and with a pressure range of 0-5 bar by means of the volumetric adsorption method. Modification of zeolite using cation exchange technique was used to determine the effect of different cation on gas adsorption characteristics. Sodium cations originally present in NaX, NaY and NaA are exchanged with calcium cations. Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX), X-Ray Diffraction (XRD) and N2 adsorption/desorption isotherms were used to characterize the structure of the prepared zeolites. The addition of conducting polymers (CPs), polythiophene (PTh) and polypyrrole (PPy), to Ca-exchanged zeolites can improve the adsorption capacities of the material and at the same time increase the selectivity of the composite. CPs/Ca-zeolite nanocomposites were prepared by adding CPs to the CaX, CaY and CaA with different weight percentages p% (p = 5, 10 and 15%). CaX/PTh-15 can be used to separate CO2 from N2 due to its high adsorption selectivity for CO2 over N2.

  1. Restrictions and satisfaction with participation in patients who are ADL-independent after an aneurysmal subarachnoid hemorrhage.

    Science.gov (United States)

    Huenges Wajer, Irene M C; Visser-Meily, Johanna M A; Greebe, Paut; Post, Marcel W M; Rinkel, Gabriel J E; van Zandvoort, Martine J E

    2017-03-01

    Most survivors of an aneurysmal subarachnoid hemorrhage (aSAH) are ADL-independent, but they often experience restrictions in (social) activities and, therefore, cannot regain their pre-morbid level of participation. In this study, participation restrictions and participation satisfaction experienced after aSAH were assessed. Moreover, possible predictors of participation after aSAH were examined to identify goals for rehabilitation. Participation restrictions experienced by a series of 67 patients visiting our SAH outpatient clinic were assessed as part of standard clinical care using the Participation Restrictions and Satisfaction sections of the Utrecht Scale for Evaluation of Rehabilitation Participation (USER-Participation) 6 months after aSAH. Cognitive impairments, cognitive and emotional complaints, and symptoms of depression and anxiety, assessed 10 weeks after aSAH, were examined as possible predictors of participation by means of linear regression analysis. Although patients were ADL-independent, 64% reported one or more participation restrictions and 60% were dissatisfied in one or more participation domains. Most commonly experienced restrictions concerned housekeeping, chores in and around the house, and physical exercise. Dissatisfaction was most often reported about outdoor activities, mobility, and work/housekeeping. The main predictors of participation restrictions as well as satisfaction with participation were cognitive complaints (subjective) (β = -.30, p = .03 and β = -.40, p = .002, respectively) and anxiety (β = .32, p = .02 and β = -.34, p = .007, respectively). Almost two-thirds of the ADL-independent patients experienced problems of participation 6 months after aSAH. Cognitive complaints (subjective) and anxiety symptoms showed the strongest association with participation restrictions and satisfaction. Cognitive rehabilitation and anxiety-reducing interventions may help to optimize rehabilitation and increase

  2. Cyber Physical System Modelling of Distribution Power Systems for Dynamic Demand Response

    Science.gov (United States)

    Chu, Xiaodong; Zhang, Rongxiang; Tang, Maosen; Huang, Haoyi; Zhang, Lei

    2018-01-01

    Dynamic demand response (DDR) is a package of control methods to enhance power system security. A CPS modelling and simulation platform for DDR in distribution power systems is presented in this paper. CPS modelling requirements of distribution power systems are analyzed. A coupled CPS modelling platform is built for assessing DDR in the distribution power system, which combines seamlessly modelling tools of physical power networks and cyber communication networks. Simulations results of IEEE 13-node test system demonstrate the effectiveness of the modelling and simulation platform.

  3. Genome-Wide Analysis of Seed Acid Detergent Lignin (ADL) and Hull Content in Rapeseed (Brassica napus L.)

    Science.gov (United States)

    Wei, Lijuan; Qu, Cunmin; Xu, Xinfu; Lu, Kun; Qian, Wei; Li, Jiana; Li, Maoteng; Liu, Liezhao

    2015-01-01

    A stable yellow-seeded variety is the breeding goal for obtaining the ideal rapeseed (Brassica napus L.) plant, and the amount of acid detergent lignin (ADL) in the seeds and the hull content (HC) are often used as yellow-seeded rapeseed screening indices. In this study, a genome-wide association analysis of 520 accessions was performed using the Q + K model with a total of 31,839 single-nucleotide polymorphism (SNP) sites. As a result, three significant associations on the B. napus chromosomes A05, A09, and C05 were detected for seed ADL content. The peak SNPs were within 9.27, 14.22, and 20.86 kb of the key genes BnaA.PAL4, BnaA.CAD2/BnaA.CAD3, and BnaC.CCR1, respectively. Further analyses were performed on the major locus of A05, which was also detected in the seed HC examination. A comparison of our genome-wide association study (GWAS) results and previous linkage mappings revealed a common chromosomal region on A09, which indicates that GWAS can be used as a powerful complementary strategy for dissecting complex traits in B. napus. Genomic selection (GS) utilizing the significant SNP markers based on the GWAS results exhibited increased predictive ability, indicating that the predictive ability of a given model can be substantially improved by using GWAS and GS. PMID:26673885

  4. Reduction in patient burdens with graphical computerized adaptive testing on the ADL scale: tool development and simulation

    Directory of Open Access Journals (Sweden)

    Wang Weng-Chung

    2009-05-01

    Full Text Available Abstract Background The aim of this study was to verify the effectiveness and efficacy of saving time and reducing burden for patients, nurses, and even occupational therapists through computer adaptive testing (CAT. Methods Based on an item bank of the Barthel Index (BI and the Frenchay Activities Index (FAI for assessing comprehensive activities of daily living (ADL function in stroke patients, we developed a visual basic application (VBA-Excel CAT module, and (1 investigated whether the averaged test length via CAT is shorter than that of the traditional all-item-answered non-adaptive testing (NAT approach through simulation, (2 illustrated the CAT multimedia on a tablet PC showing data collection and response errors of ADL clinical functional measures in stroke patients, and (3 demonstrated the quality control of endorsing scale with fit statistics to detect responding errors, which will be further immediately reconfirmed by technicians once patient ends the CAT assessment. Results The results show that endorsed items could be shorter on CAT (M = 13.42 than on NAT (M = 23 at 41.64% efficiency in test length. However, averaged ability estimations reveal insignificant differences between CAT and NAT. Conclusion This study found that mobile nursing services, placed at the bedsides of patients could, through the programmed VBA-Excel CAT module, reduce the burden to patients and save time, more so than the traditional NAT paper-and-pencil testing appraisals.

  5. Towards False Alarm Reduction using Fuzzy If-Then Rules for Medical Cyber Physical Systems

    DEFF Research Database (Denmark)

    Li, Wenjuan; Meng, Weizhi; Su, Chunhua

    2018-01-01

    Cyber-Physical Systems (CPS) are integrations of computation, networking and physical processes. Its process control is often referred to as embedded systems. Generally, CPS and Internet of Things (IoT) have the same basic architecture, whereas the former shows a higher combination and coordination...

  6. Development of a cross-polarization scattering system for the measurement of internal magnetic fluctuations in the DIII-D tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Rhodes, T. L., E-mail: trhodes@ucla.edu; Peebles, W. A.; Crocker, N. A.; Nguyen, X. [Physics and Astronomy Department, University of California, Los Angeles, California 90098 (United States)

    2014-11-15

    The design and performance of a new cross-polarization scattering (CPS) system for the localized measurement of internal magnetic fluctuations is presented. CPS is a process whereby magnetic fluctuations scatter incident electromagnetic radiation into a perpendicular polarization which is subsequently detected. A new CPS design that incorporates a unique scattering geometry was laboratory tested, optimized, and installed on the DIII-D tokamak. Plasma tests of signal-to-noise, polarization purity, and frequency response indicate proper functioning of the system. CPS data show interesting features related to internal MHD perturbations known as sawteeth that are not observed on density fluctuations.

  7. Positioning navigation and timing service applications in cyber physical systems

    Science.gov (United States)

    Qu, Yi; Wu, Xiaojing; Zeng, Lingchuan

    2017-10-01

    The positioning navigation and timing (PNT) architecture was discussed in detail, whose history, evolvement, current status and future plan were presented, main technologies were listed, advantages and limitations of most technologies were compared, novel approaches were introduced, and future capacities were sketched. The concept of cyber-physical system (CPS) was described and their primary features were interpreted. Then the three-layer architecture of CPS was illustrated. Next CPS requirements on PNT services were analyzed, including requirements on position reference and time reference, requirements on temporal-spatial error monitor, requirements on dynamic services, real-time services, autonomous services, security services and standard services. Finally challenges faced by PNT applications in CPS were concluded. The conclusion was expected to facilitate PNT applications in CPS, and furthermore to provide references to the design and implementation of both architectures.

  8. Review of the Potential for a Cyber-Physical System Approach to Temporary Structures Monitoring

    Directory of Open Access Journals (Sweden)

    Xiao Yuan

    2015-11-01

    Full Text Available Around three quarters of construction workers work on or near temporary structures, whose failures lead to more than 100 deaths, 4500 injuries, and damage costing $90 million each year in the United States. However, few of the temporary structural problems have been well addressed, especially when compared with the increasing improvements in permanent structures. Meanwhile, the review of leading causes of temporary structural failures identifies the need for improved methods, such as Cyber-Physical Systems (CPS, to prevent potential structural hazards. This paper makes the first effort to examine CPS applicability in temporary structures, and potential benefits brought by CPS to temporary structural monitoring. Key definitions and features of CPS, CPS applications in both other industry sectors and the built environment, and applications of CPS enabling technologies in temporary structures are reviewed. It is concluded that CPS provides opportunity to address safety and structural problems of temporary structures. For a clear understanding of how CPS works in structural monitoring, an application scenario of scaffolding system is presented. Finally, system requirements followed by a system architecture are identified.

  9. The Effects of the Classroom Performance System on Student Participation, Attendance, and Achievement

    Science.gov (United States)

    Termos, Mohamad Hani

    2013-01-01

    The Classroom Performance System (CPS) is an instructional technology that increases student performance and promotes active learning. This study assessed the effect of the CPS on student participation, attendance, and achievement in multicultural college-level anatomy and physiology classes, where students' first spoken language is not English.…

  10. Risk Factors for Nursing Home Placement in Alzheimer's Disease: A Longitudinal Study of Cognition, ADL, Service Utilization, and Cholinesterase Inhibitor Treatment

    Science.gov (United States)

    Wattmo, Carina; Wallin, Asa K.; Londos, Elisabet; Minthon, Lennart

    2011-01-01

    Purpose of the Study: To identify risk factors for early nursing home placement (NHP) in Alzheimer's disease (AD), focusing on the impact of longitudinal change in cognition, activities of daily living (ADL), service utilization, and cholinesterase inhibitor treatment (ChEI). Design and Methods: In an open, 3-year, prospective, multicenter study…

  11. A Type System for Certified Binaries

    National Research Council Canada - National Science Library

    Shao, Zhong; Trifonov, Valery; Saha, Bratin; Papaspyrou, Nikolaos

    2004-01-01

    ... (CPS and closure conversion) while preserving proofs represented in the type system. Our work provides a foundation for the process of automatically generating certified binaries in a type-theoretic framework.

  12. Improvements on computerized procedure system of advanced power reactor 1400 MWe

    International Nuclear Information System (INIS)

    Seong, Nokyu; Jung, Yeonsub; Sung, Chanho; Kang, Sungkon

    2017-01-01

    Plant procedures are instructions to help operator in monitoring, decision making, and controlling Nuclear Power Plants (NPPs). While plant procedures conventionally have been paper-based, computerized-based procedures are being implemented to reduce the drawbacks of paper-based procedures in many nuclear power plants. The Computerized Procedure System (CPS) designed by Korea Hydro and Nuclear Power Central Research Institute (KHNP CRI) is one of the human-system interfaces (HSIs) in digitalized Main Control Room (MCR) of APR1400 (Advanced Power Reactor 1400 MWe). Currently, CPS is being applied to constructing nuclear power plants of Korea and Barakah NPP 1, 2, 3 and 4 units of United Arab Emirates. The CPS has many advantages to perform the procedure in fully digitalized MCR. First, CPS provides the procedure flow with logic diagram to operators. The operator easily can be aware of the procedure flow from a previous instruction to the next instruction and also can find out the relation between parent instruction and child instructions such as AND, OR and SEQUENCE logics. Second, CPS has three logic-based functions such as procedure entry condition monitoring logic, continuously applied step (CAS) re-execution monitoring logic and auto evaluation logic on instructions. E.g. CPS provides the standard post trip actions procedure open popup message when the reactor trips by calculating the entry condition logic that procedure writer had made in the writing process. Third, CPS can directly display the task information related to instructions such as valves, pumps, process parameters, etc. and also the operator can call the system display related to procedure execution. If an operator clicks the system display link, the related system display popups on the right side monitor of CPS display. Lastly, CPS supports the synchronization of procedure among the operators. This synchronization function helps operators to succeed the goal of procedure and improve the situation

  13. Security and Privacy in Cyber-Physical Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fink, Glenn A.; Edgar, Thomas W.; Rice, Theora R.; MacDonald, Douglas G.; Crawford, Cary E.

    2016-08-30

    As you have seen from the previous chapters, cyber-physical systems (CPS) are broadly used across technology and industrial domains. While these systems enable process optimization and efficiency and allow previously impossible functionality, security and privacy are key concerns for their design, development, and operation. CPS have been key components utilized in some of the highest publicized security breaches over the last decade. In this chapter, we will look over the CPS described in the previous chapters from a security perspective. In this chapter, we explain classical information and physical security fundamentals in the context of CPS and contextualize them across application domains. We give examples where the interplay of functionality and diverse communication can introduce unexpected vulnerabilities and produce larger impacts. We will discuss how CPS security and privacy is inherently different from that of pure cyber or physical systems and what may be done to secure these systems, considering their emergent cyber-physical properties. Finally, we will discuss security and privacy implications of merging infrastructural and personal CPS. Our hope is to impart the knowledge of what CPS security and privacy are, why they are important, and explain existing processes and challenges.

  14. Sharing more than friendship--nasal colonization with coagulase-positive staphylococci (CPS and co-habitation aspects of dogs and their owners.

    Directory of Open Access Journals (Sweden)

    Birgit Walther

    Full Text Available BACKGROUND: Since the relationship between dogs and their owners has changed, and dogs moved from being working dogs to family members in post-industrial countries, we hypothesized that zoonotic transmission of opportunistic pathogens like coagulase positive staphylococci (CPS is likely between dogs and their owners. METHODOLOGY/PRINCIPAL FINDINGS: CPS- nasal carriage, different aspects of human-to-dog relationship as well as potential interspecies transmission risk factors were investigated by offering nasal swabs and a questionnaire to dog owners (108 and their dogs (108 at a dog show in 2009. S. aureus was found in swabs of 20 (18.5% humans and two dogs (1.8%, and spa types which correspond to well known human S. aureus lineages dominated (e.g. CC45, CC30 and CC22. Multilocus sequence typing (MLST of the two canine strains revealed ST72 and ST2065 (single locus variant of ST34. Fifteen dogs (13.9% and six owners (5.6% harboured S. pseudintermedius, including one mecA-positive human isolate (MRSP. Pulsed field gel electrophoresis (PFGE revealed that one dog/owner pair harboured indistinguishable S. pseudintermedius- isolates of ST33. Ten (48% of the 21 S. pseudintermedius-isolates showed resistance towards more than one antimicrobial class. 88.9% of the dog owners reported to allow at least one dog into the house, 68.5% allow the dog(s to rest on the sofa, 39.8% allow their dogs to come onto the bed, 93.5% let them lick their hands and 52.8% let them lick their face. Bivariate analysis of putative risk factors revealed that dog owners who keep more than two dogs have a significantly higher chance of being colonized with S. pseudintermedius than those who keep 1-2 dogs (p<0.05. CONCLUSIONS/RECOMMENDATIONS: In conclusion, CPS transmission between dog owners and their dogs is possible. Further investigation regarding interspecies transmission and the diverse adaptive pathways influencing the epidemiology of CPS (including MRSA and MRSP in

  15. Sharing More than Friendship — Nasal Colonization with Coagulase-Positive Staphylococci (CPS) and Co-Habitation Aspects of Dogs and Their Owners

    Science.gov (United States)

    Walther, Birgit; Hermes, Julia; Cuny, Christiane; Wieler, Lothar H.; Vincze, Szilvia; Abou Elnaga, Yassmin; Stamm, Ivonne; Kopp, Peter A.; Kohn, Barbara; Witte, Wolfgang; Jansen, Andreas; Conraths, Franz J.; Semmler, Torsten; Eckmanns, Tim; Lübke-Becker, Antina

    2012-01-01

    Background Since the relationship between dogs and their owners has changed, and dogs moved from being working dogs to family members in post-industrial countries, we hypothesized that zoonotic transmission of opportunistic pathogens like coagulase positive staphylococci (CPS) is likely between dogs and their owners. Methodology/Principal Findings CPS- nasal carriage, different aspects of human-to-dog relationship as well as potential interspecies transmission risk factors were investigated by offering nasal swabs and a questionnaire to dog owners (108) and their dogs (108) at a dog show in 2009. S. aureus was found in swabs of 20 (18.5%) humans and two dogs (1.8%), and spa types which correspond to well known human S. aureus lineages dominated (e.g. CC45, CC30 and CC22). Multilocus sequence typing (MLST) of the two canine strains revealed ST72 and ST2065 (single locus variant of ST34). Fifteen dogs (13.9%) and six owners (5.6%) harboured S. pseudintermedius, including one mecA-positive human isolate (MRSP). Pulsed field gel electrophoresis (PFGE) revealed that one dog/owner pair harboured indistinguishable S. pseudintermedius- isolates of ST33. Ten (48%) of the 21 S. pseudintermedius-isolates showed resistance towards more than one antimicrobial class. 88.9% of the dog owners reported to allow at least one dog into the house, 68.5% allow the dog(s) to rest on the sofa, 39.8% allow their dogs to come onto the bed, 93.5% let them lick their hands and 52.8% let them lick their face. Bivariate analysis of putative risk factors revealed that dog owners who keep more than two dogs have a significantly higher chance of being colonized with S. pseudintermedius than those who keep 1–2 dogs (p<0.05). Conclusions/Recommendations In conclusion, CPS transmission between dog owners and their dogs is possible. Further investigation regarding interspecies transmission and the diverse adaptive pathways influencing the epidemiology of CPS (including MRSA and MRSP) in different

  16. Glittre-ADL Multiple Tasks Induce Similar Dynamic Hyperinflation With Different Metabolic and Ventilatory Demands in Patients With COPD.

    Science.gov (United States)

    Gulart, Aline Almeida; Munari, Anelise Bauer; Tressoldi, Caroline; Dos Santos, Karoliny; Karloh, Manuela; Mayer, Anamaria Fleig

    2017-11-01

    This cross-sectional study compared the physiological responses and dynamic hyperinflation (DH) of the Glittre-ADL test (TGlittre) and its specific tasks in patients with chronic obstructive pulmonary disease (COPD). Thirty patients with COPD performed the TGlittre. The individual tasks included stand up and sit down (TSS); climb up and down stairs (TSTAIRS); walk on a flat surface (TWALK); and move objects onto and off a shelf (TSHELF). While performing these tasks, the physiological responses were evaluated and inspiratory capacity measured before and immediately after the tests. All physiological variables and inspiratory capacity were different at the end of the TGlittre and its tasks compared with baseline (P .05), which were the tasks with the greatest physiological requirement, whereas the TSS represented the lowest metabolic, cardiovascular, and ventilatory demands among TGlittre's tasks. DH did not differ significantly among TGlittre's tasks. TWALK and TSHELF were the tasks that resulted in greater physiological overload, whereas TSS induced the lowest metabolic and ventilatory demands. Despite this, DH did not differ among the TGlittre's tasks in patients with COPD.

  17. Identification of the cpsA gene as a specific marker for the discrimination of Streptococcus pneumoniae from viridans group streptococci.

    Science.gov (United States)

    Park, Hee Kuk; Lee, Sang-Jae; Yoon, Jang Won; Shin, Jong Wook; Shin, Hyoung-Shik; Kook, Joong-Ki; Myung, Soon Chul; Kim, Wonyong

    2010-10-01

    Streptococcus pneumoniae, the aetiological agent of pneumonia and non-gonococcal urethritis, shares a high degree of DNA sequence identity with the viridans group of streptococci, particularly Streptococcus mitis and Streptococcus oralis. Although their clinical and pathological manifestations are different, discrimination between S. pneumoniae and its close viridans cocci relatives is still quite difficult. Suppression subtractive hybridization was performed to identify the genomic differences between S. pneumoniae and S. mitis. Thirty-four resulting S. pneumoniae-specific clones were examined by sequence determination and comparative DNA sequence analysis using blast. S. pneumoniae-specific primers were subsequently designed from one of the clonal DNA sequences containing the cps gene (coding for capsular polysaccharide biosynthesis). The primer specificities were evaluated using 49 viridans streptococci including 26 S. pneumoniae, 54 other streptococci, 14 Lactococcus species, 14 Enterococcus species and three Vagococcus species, and compared with the specificities of previously described autolysin (lytA), pneumolysin (ply), Spn9802 and Spn9828 primers. The newly designed cpsA-specific primer set was highly specific to S. pneumoniae and was even better than the existing primers. These findings may help improve the rapid identification and differentiation of S. pneumoniae from closely related members of the viridans group streptococci.

  18. [The effects of hand acupuncture therapy on pain, ROM, ADL and depression among elders with low back pain and knee joint pain].

    Science.gov (United States)

    Yang, Jin-Hyang

    2009-02-01

    The purpose of this study was to identify the effects of hand acupuncture therapy on pain, ROM, ADL, and depression among older people with low back pain and knee joint pain. The research was a quasi-experimental design using a non-equivalent control group pre-post test. The participants were 40 patients, 18 in the experimental group and 22 in the control group. A pretest and 2 posttest were conducted to measure the main variables. For the experimental group, hand acupuncture therapy, consisting of hand acupuncture and press-pellets based on corresponding points, was given. There were statistically significant differences in pain, ROM in knee joint, and ADL in the experimental group but not in depression compared to the control group over two different times. The hand acupuncture therapy was effective for low back pain, knee joint pain, ROM in knee joint and ADL among the elders in this study. Therefore, the hand acupuncture therapy can be utilized in the field of geriatric nursing as a nursing intervention for older people with low back pain and knee joint pain.

  19. Synergistic antidepressant-like effects between a kappa opioid antagonist (LY2444296) and a delta opioid agonist (ADL5859) in the mouse forced swim test.

    Science.gov (United States)

    Huang, Peng; Tunis, Julia; Parry, Christopher; Tallarida, Ronald; Liu-Chen, Lee-Yuan

    2016-06-15

    Kappa opioid (KOP) receptor antagonists and delta opioid (DOP) receptor agonists have antidepressant-like effects in animal tests and may be useful for treatment-resistant depression in humans. In this study, we examined whether the combination of a KOP receptor antagonist and a DOP receptor agonist would produce a better than additive effect (i.e. synergy). LY2444296 is a short-acting selective nonpeptide KOP receptor antagonist. ADL5859 is a selective nonpeptide DOP receptor agonist which does not produce seizures and EEG disturbances. Each compound and combinations of the two were examined in the forced swim test (FST) one h post injection, a screening test for antidepressant-like effect, in male adult C57BL/6J mice (Jackson Lab). LY2444296 [subcutaneous (s.c.) injection] at 10 and 30mg/kg, but not 3mg/kg, significantly decreased immobility time in a dose-dependent manner. Intraperitoneal (i.p.) injections of ADL5859 also reduced immobility time dose-dependently at doses of 3 and 10mg/kg, but not at 1mg/kg. An analysis was conducted using the method of Tallarida and Raffa (2010), which employed dose equivalence. The relative potency of the drugs was determined to be LY2444296: ADL5859=1:0.28, which was the dose ratio for combination studies. Six combinations of the two compounds were tested in mice at a fixed dose ratio. We found that LY2444296 and ADL5859 yielded significant synergistic effects for the antidepressant-like effect at the combined dose ranging from 3.84mg/kg to 9.0mg/kg. ADL5859 (10mg/kg), LY2444296 (30mg/kg) and their combined dose (3.84mg/kg) had no effects on locomotor activities. Since the two drugs have distinct pharmacological profiles, such a synergism will allow use of lower doses of both drugs to achieve desired antidepressant effects with fewer side effects. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. A Cyber Physical Model Based on a Hybrid System for Flexible Load Control in an Active Distribution Network

    Directory of Open Access Journals (Sweden)

    Yun Wang

    2017-02-01

    Full Text Available To strengthen the integration of the primary and secondary systems, a concept of Cyber Physical Systems (CPS is introduced to construct a CPS in Power Systems (Power CPS. The most basic work of the Power CPS is to build an integration model which combines both a continuous process and a discrete process. The advanced form of smart grid, the Active Distribution Network (ADN is a typical example of Power CPS. After designing the Power CPS model architecture and its application in ADN, a Hybrid System based model and control method of Power CPS is proposed in this paper. As an application example, ADN flexible load is modeled and controlled with ADN feeder power control by a control strategy which includes the normal condition and the underpowered condition. In this model and strategy, some factors like load power consumption and load functional demand are considered and optimized. In order to make up some of the deficiencies of centralized control, a distributed control method is presented to reduce model complexity and improve calculation speed. The effectiveness of all the models and methods are demonstrated in the case study.

  1. Network Location-Aware Service Recommendation with Random Walk in Cyber-Physical Systems

    Directory of Open Access Journals (Sweden)

    Yuyu Yin

    2017-09-01

    Full Text Available Cyber-physical systems (CPS have received much attention from both academia and industry. An increasing number of functions in CPS are provided in the way of services, which gives rise to an urgent task, that is, how to recommend the suitable services in a huge number of available services in CPS. In traditional service recommendation, collaborative filtering (CF has been studied in academia, and used in industry. However, there exist several defects that limit the application of CF-based methods in CPS. One is that under the case of high data sparsity, CF-based methods are likely to generate inaccurate prediction results. In this paper, we discover that mining the potential similarity relations among users or services in CPS is really helpful to improve the prediction accuracy. Besides, most of traditional CF-based methods are only capable of using the service invocation records, but ignore the context information, such as network location, which is a typical context in CPS. In this paper, we propose a novel service recommendation method for CPS, which utilizes network location as context information and contains three prediction models using random walking. We conduct sufficient experiments on two real-world datasets, and the results demonstrate the effectiveness of our proposed methods and verify that the network location is indeed useful in QoS prediction.

  2. Network Location-Aware Service Recommendation with Random Walk in Cyber-Physical Systems.

    Science.gov (United States)

    Yin, Yuyu; Yu, Fangzheng; Xu, Yueshen; Yu, Lifeng; Mu, Jinglong

    2017-09-08

    Cyber-physical systems (CPS) have received much attention from both academia and industry. An increasing number of functions in CPS are provided in the way of services, which gives rise to an urgent task, that is, how to recommend the suitable services in a huge number of available services in CPS. In traditional service recommendation, collaborative filtering (CF) has been studied in academia, and used in industry. However, there exist several defects that limit the application of CF-based methods in CPS. One is that under the case of high data sparsity, CF-based methods are likely to generate inaccurate prediction results. In this paper, we discover that mining the potential similarity relations among users or services in CPS is really helpful to improve the prediction accuracy. Besides, most of traditional CF-based methods are only capable of using the service invocation records, but ignore the context information, such as network location, which is a typical context in CPS. In this paper, we propose a novel service recommendation method for CPS, which utilizes network location as context information and contains three prediction models using random walking. We conduct sufficient experiments on two real-world datasets, and the results demonstrate the effectiveness of our proposed methods and verify that the network location is indeed useful in QoS prediction.

  3. High Assurance Control of Cyber-Physical Systems with Application to Unmanned Aircraft Systems

    Science.gov (United States)

    Kwon, Cheolhyeon

    With recent progress in the networked embedded control technology, cyber attacks have become one of the major threats to Cyber-Physical Systems (CPSs) due to their close integration of physical processes, computational resources, and communication capabilities. While CPSs have various applications in both military and civilian uses, their on-board automation and communication afford significant advantages over a system without such abilities, but these benefits come at the cost of possible vulnerability to cyber attacks. Traditionally, most cyber security studies in CPSs are mainly based on the computer security perspective, focusing on issues such as the trustworthiness of data flow, without rigorously considering the system's physical processes such as real-time dynamic behaviors. While computer security components are key elements in the hardware/software layer, these methods alone are not sufficient for diagnosing the healthiness of the CPSs' physical behavior. In seeking to address this problem, this research work proposes a control theoretic perspective approach which can accurately represent the interactions between the physical behavior and the logical behavior (computing resources) of the CPS. Then a controls domain aspect is explored extending beyond just the logical process of the CPS to include the underlying physical behavior. This approach will allow the CPS whose physical operations are robust/resilient to the damage caused by cyber attacks, successfully complementing the existing CPS security architecture. It is important to note that traditional fault-tolerant/robust control methods could not be directly applicable to achieve resiliency against malicious cyber attacks which can be designed sophisticatedly to spoof the security/safety monitoring system (note this is different from common faults). Thus, security issues at this layer require different risk management to detect cyber attacks and mitigate their impact within the context of a unified

  4. Middleware Challenges for Cyber-Physical Systems

    DEFF Research Database (Denmark)

    Mohamed, Nader; Al-Jaroodi, Jameela; Lazarova-Molnar, Sanja

    2017-01-01

    to provide advanced monitoring and control mechanisms geared towards enhancing the targeted physical system or environment. These components function seamlessly to offer specific functionalities that help enhance human lives, physical system operations and environments. While CPS can offer many smart......Cyber-Physical Systems (CPS) are being developed to provide useful interactions between physical systems and environments and cyber world for a variety of applications. CPS are designed with a set of software and interconnected distributed hardware components that are linked with physical elements...... enhancements for improving physical processes, the development of such complex systems composed of many distributed and heterogeneous components is extremely difficult. This is due to the many communication, computing, and networking challenges. Using an appropriate middleware that provides a framework...

  5. Temperature dependence of the rate constant of hydrogen isotope interactions with a lithium capillary-porous system under reactor irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Tazhibayeva, Irina, E-mail: tazhibayeva@ntsc.kz [Institute of Atomic Energy NNC RK, Kurchatov (Kazakhstan); Kulsartov, Timur; Gordienko, Yuri [Institute of Atomic Energy NNC RK, Kurchatov (Kazakhstan); Mukanova, Aliya [Al’ Farabi Kazakh National University, Almaty (Kazakhstan); Ponkratov, Yuri; Barsukov, Nikolay; Tulubaev, Evgeniy [Institute of Atomic Energy NNC RK, Kurchatov (Kazakhstan); Platacis, Erik [University of Latvia (IPUL), Riga (Latvia); Kenzhin, Ergazy [Shakarim Semey State University, Semey (Kazakhstan)

    2013-10-15

    Highlights: • The experiments with Li CPS sample were carried out at reactor IVG-1.M. • The gas absorption technique was used to study hydrogen isotope interaction with lithium CPS. • The temperature dependence of constants of interaction rate was obtained for various power rates of the reactor. • Determination of the activation energies, and pre-exponents of Arrhenius dependence. • The effect of increase of the rate constant under reaction irradiation. -- Abstract: Experiments with a sample of a lithium capillary-porous system (CPS) were performed at the reactor IVG-1.M of the Institute of Atomic Energy NNC RK to study the effects of neutron irradiation on the parameters of hydrogen isotope interactions with a lithium CPS. The absorption technique was used during the experiments, and this technique allowed the temperature dependences of the hydrogen isotope interaction rate constants with the lithium CPS to be obtained under various reactor powers. The obtained dependencies were used to determine the main interaction parameters: the activation energies and the pre-exponents of the Arrhenius dependence of the hydrogen interaction rate constants with lithium and the lithium CPS. An increase of the hydrogen isotope interaction rate with the lithium CPS was observed under reactor irradiation.

  6. Function generation and regulation libraries and their application to the control of the new main power converter (POPS) at the CERN CPS

    International Nuclear Information System (INIS)

    King, Q.; Page, S.T.; Thiesen, H.; Veenstra, M.

    2012-01-01

    Power converter control for the LHC is based on an embedded control computer called a Function Generator/Controller (FGC). Every converter includes an FGC with responsibility for the generation of the reference current as a function of time and the regulation of the circuit current, as well as control of the converter state. With many new converter controls software classes in development it was decided to generalize several key components of the FGC software in the form of C libraries: function generation in libfg, regulation, limits and simulation in libreg and DCCT, ADC and DAC calibration in libcal. These libraries were first used in the software class dedicated to controlling the new 60 MW main power converter (POPS) at the CERN Proton Synchrotron (CPS) where regulation of both magnetic field and circuit current is supported. This paper reports on the functionality provided by each library and in particular libfg and libreg. The libraries are already being used by software classes in development for the next generation FGC for Linac4 converters, as well as the CERN SPS converter controls (MUGEF) and MedAustron converter regulation board. (authors)

  7. Reliability of Cyber Physical Systems with Focus on Building Management Systems

    DEFF Research Database (Denmark)

    Lazarova-Molnar, Sanja; Shaker, Hamid Reza; Mohamed, Nader

    2016-01-01

    Cyber-physical systems are slowly emerging to dominate our world. Cyber-physical systems (CPS) are systems that tightly integrates users, devices and software. Whereas many of these systems are obviously safety-critical systems, some of them become so under special circumstances. This is the case...... with our focus CPS, i.e. building management systems (BMS), which are not always safety critical per se, but under special circumstances they can become such. This certainly depends on the purpose of the building. We can easily imagine BMS of hospital buildings as safety-critical, but also BMS of buildings...... that store sensitive materials and equipment that could be of biological nature or encompassing sensitive technology that would need special temperature, humidity and light settings. For this reason, in this paper we would like to emphasize on the importance of reliability of CPS in general, with a special...

  8. Characterizing Decision Support Telemedicine Systems

    NARCIS (Netherlands)

    Nannings, B.; Abu-Hanna, A.

    2006-01-01

    OBJECTIVES: Decision Support Telemedicine Systems (DSTS) are at the intersection of two disciplines: tele-medicine and clinical decision support systems (CDSS). The objective of this paper is to provide a set of characterizing properties for DSTSs. This characterizing property set (CPS) can be used

  9. ATR/OTR-SY Tank Camera Purge System and in Tank Color Video Imaging System

    International Nuclear Information System (INIS)

    Werry, S.M.

    1995-01-01

    This procedure will document the satisfactory operation of the 101-SY tank Camera Purge System (CPS) and 101-SY in tank Color Camera Video Imaging System (CCVIS). Included in the CPRS is the nitrogen purging system safety interlock which shuts down all the color video imaging system electronics within the 101-SY tank vapor space during loss of nitrogen purge pressure

  10. Tradução, validação e adaptação cultural da escala de atividade de vida diária Translation, validation and cultural adaptation of the 'activities of daily living' scale (ADLS

    Directory of Open Access Journals (Sweden)

    Priscila Zeitune Nigri

    2007-01-01

    Full Text Available OBJETIVO: Realizar a tradução, adaptação cultural e validação do "Knee Outcome Survey- Activities of Daily Living Scale" (ADLS para a língua portuguesa, bem como verificar suas propriedades de medida, reprodutibilidade e validade, para que o mesmo possa ser usado como um instrumento específico para avaliação de sintomas em pacientes brasileiros portadores de afecções no joelho durante as atividades de vida diária. MÉTODOS: Foram realizadas 2 entrevistas,na primeira o questionário foi aplicado em conjunto ao Lysholm, SF-36 e EAV (examinador 1. Após aproximadamente 30 minutos da primeira entrevista, os mesmos pacientes responderam apenas ao ADLS (examinador 2. Após um intervalo entre 7 a 10 dias, foi realizada a terceira entrevista constituída de nova aplicação do ADLS (examinador 2. RESULTADOS: A amostra consistiu de 53 entrevistados, sendo a média de idade de 33.0566 anos e patologia mais freqüente a lesão ligamentar (56,6%. O índice de Sperman obteve um valor de 0,986 (alfa=0,05, roOBJECTIVES: To perform the translation, cultural adaptation and validation of the "Knee Outcome Survey - Activities of Daily Living Scale" (ADLS into Portuguese, as well as to check its measurement, reproducibility and validity properties in order to make it useful as a specific instrument for evaluating symptoms in Brazilian patients with knee injuries during their daily living activities. METHODS: Two interviews were performed; in the first interview, the questionnaire was applied along with Lysholm's, SF-36 and VAS (investigator 1. Approximately 30 minutes after the first interview, the same patients answered only the ADLS (investigator 2. After a break of 7 to 10 days, a third additional interview with the ADLS was applied (investigator 2. RESULTS: The sample was constituted of 53 subjects, with mean age of 33.0566 years, with the most frequent pathology being ligamentar injury (56.6%. The Spearman's index used for inter

  11. Industrial Internet of Things cybermanufacturing systems

    CERN Document Server

    Brecher, Christian; Song, Houbing; Rawat, Danda

    2017-01-01

    Developing the core system science needed to enable the development of a complex industrial internet of things/manufacturing CPS (IIoT/M-CPS), this book will foster a research community committed to advancing research and education in IIoT/M-CPS and to transitioning applicable science and technology into engineering practice. Presenting the current state IIoT and the concept of cybermanufacturing, this book is at the nexus of research advances from the engineering and computer and information science domains. It features contributions from leading experts in the field with years of experience in advancing manufacturing. Readers will acquire the core system science needed to transform to cybermanufacturing that spans the full spectrum from ideation to physical realization.

  12. Randomized prospective study of olecranon fracture fixation: cable pin system versus tension band wiring.

    Science.gov (United States)

    Liu, Q-H; Fu, Z-G; Zhou, J-L; Lu, T; Liu, T; Shan, L; Liu, Y; Bai, L

    2012-01-01

    This prospective, randomized study compared the effectiveness of the cable pin system (CPS) versus tension band wiring (TBW) for olecranon fracture fixation. Patients with acute transverse or slight oblique olecranon fractures were randomly divided into two groups: one fixed by CPS and the other by TBW. Clinical outcome data were collected and analysed following a mean duration of 21 months. The mean ± SD fracture healing time was significantly shorter in the CPS group (n = 30; 9.73 ± 2.02 weeks) compared with the TBW group (n = 32; 11.13 ± 2.21 weeks). One patient in the CPS group and seven patients in the TBW group experienced postoperative complications; this difference was statistically significant. The mean ± SD Mayo Elbow Performance Score in the CPS group was significantly higher (88.67 ± 6.42) than that in the TBW group (80.78 ± 11.99). Logistic regression analysis showed an association between fixation method and fracture healing time, complications and elbow function. Internal fixation by CPS is an effective method for olecranon fracture and is associated with a shorter healing time, fewer complications and better function than TBW.

  13. Comparison of Tension-Band Wiring With the Cable Pin System in Patella Fractures: A Randomized Prospective Study.

    Science.gov (United States)

    Tian, Qing-xian; Hai, Yong; Du, Xin-ru; Xu, Zi-yu; Lu, Tie; Shan, Lei; Liu, Yang; Zhou, Jun-lin

    2015-12-01

    To compare the outcome of tension-band wiring (TBW) with the cable pin system (CPS) for transverse fractures of the patella. Randomized prospective study. Academic Level I trauma center. From February 2008 to December 2011, 73 consecutive patients with transverse fractures of the patella were prospectively enrolled in this study. The patients were randomly divided into 2 groups: one group was treated using the CPS, and the other group was treated using the modified TBW. The clinical outcome assessment included analyses of the radiographic images, the modified Hospital for Special Surgery scoring system, and complications. The follow-up time ranged from 12 to 29 months. All fractures healed, with a union rate of 100%. The fracture healing time was significantly shorter in the CPS group (8.51 ± 2.59 weeks, n = 34) compared with the TBW group (11.79 ± 3.04 weeks, n = 39). Postoperative complications in the CPS and TBW groups were observed in 1 and 9 patients, respectively, a difference that was statistically significant. The mean Hospital for Special Surgery score for the CPS group (90.53 ± 5.19 points) was significantly higher than that for the TBW group (81.36 ± 12.71 points). The CPS is a viable option for transverse fractures of the patella and is associated with a shorter healing time, fewer complications, and better function than TBW. Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.

  14. Towards a Semantic Web of Things: A Hybrid Semantic Annotation, Extraction, and Reasoning Framework for Cyber-Physical System

    Directory of Open Access Journals (Sweden)

    Zhenyu Wu

    2017-02-01

    Full Text Available Web of Things (WoT facilitates the discovery and interoperability of Internet of Things (IoT devices in a cyber-physical system (CPS. Moreover, a uniform knowledge representation of physical resources is quite necessary for further composition, collaboration, and decision-making process in CPS. Though several efforts have integrated semantics with WoT, such as knowledge engineering methods based on semantic sensor networks (SSN, it still could not represent the complex relationships between devices when dynamic composition and collaboration occur, and it totally depends on manual construction of a knowledge base with low scalability. In this paper, to addresses these limitations, we propose the semantic Web of Things (SWoT framework for CPS (SWoT4CPS. SWoT4CPS provides a hybrid solution with both ontological engineering methods by extending SSN and machine learning methods based on an entity linking (EL model. To testify to the feasibility and performance, we demonstrate the framework by implementing a temperature anomaly diagnosis and automatic control use case in a building automation system. Evaluation results on the EL method show that linking domain knowledge to DBpedia has a relative high accuracy and the time complexity is at a tolerant level. Advantages and disadvantages of SWoT4CPS with future work are also discussed.

  15. XCPS: A tool to eXplore cyber physical systems

    NARCIS (Netherlands)

    Adyanthaya, S.; Ara, H.A.; Bastos, J.; Behrouzian, A.; Sánchez, R.M.; Pinxten, J. van; Sanden, B. van der; Waqas, U.; Basten, T.; Corporaal, H.; Frijns, R.; Geilen, M.; Goswami, D.; Stuijk, S.; Reniers, M.; Voeten, J.

    2015-01-01

    Cyber-Physical Systems (CPS) play an important role in the modern high-tech industry. Designing such systems is a challenging task due to the multi-disciplinary nature of these systems, and the range of abstraction levels involved. To facilitate hands-on experience with such systems, we develop a

  16. Cyber physical systems approach to smart electric power grid

    CERN Document Server

    Khaitan, Siddhartha Kumar; Liu, Chen Ching

    2015-01-01

    This book documents recent advances in the field of modeling, simulation, control, security and reliability of Cyber- Physical Systems (CPS) in power grids. The aim of this book is to help the reader gain insights into working of CPSs and understand their potential in transforming the power grids of tomorrow. This book will be useful for all those who are interested in design of cyber-physical systems, be they students or researchers in power systems, CPS modeling software developers, technical marketing professionals and business policy-makers.

  17. Egocentric interaction as a tool for designing ambient ecologies – The case of the easy ADL ecology

    DEFF Research Database (Denmark)

    Surie, Dipak; Janlert, Lars-Erik; Pederson, Thomas

    2012-01-01

    ambient intelligence could be realised. This work describes such an ambient ecological system comprising of a set of smart everyday objects, a personal activity-centric middleware, a set of mock-up ubiquitous computing applications and a human agent within a living laboratory home environment...

  18. A study on Requirements of Data Base Translator for APR1400 Computerized Procedure System at Shin-Hanul unit 1 and 2

    International Nuclear Information System (INIS)

    Seong, Nokyu; Lee, Sungjin

    2015-01-01

    The CPS is one of the Man Machine Interface (MMI) resources and the CPS can directly display plant graphic objects which are in the Digital Control System (DCS). And the CPS can send a request to DCS to provide DCS screen which is called step support display through DCS link button on a computerized procedure. The procedure writers can insert DCS graphic information to computerized procedure through data base which is provided by CPS Editing System (CPSES). The data base which is provided by CPSES conforms to the naming rule of DCS graphic objects. The naming rule of DCS graphic objects is defined by vendor thus status of DCS graphic objects which are in computerized procedure at Shin-Kori plant cannot be displayed on CPS at Shin-Hanul plant. To use computerized procedure which is written by other plant procedure writer, DCS graphic objects shall be translated by its plant data base. This paper introduces requirements of data base translator to reduce translation and re-inserting graphic objects burden. This paper introduces the requirements of data base translator of CPSES for APR1400 CPS at Shin-Hanul unit 1 and 2. The translator algorithms shall be tested to update data base of CPSES effectively. The prototype of translator is implemented and is being tested using real plant DB. This translator can be applied to Shin- Hanul unit1 and 2 through software V and V

  19. Aiming for a fully integrated computerized procedure system

    International Nuclear Information System (INIS)

    Marron, J. E.

    2006-01-01

    A fully integrated Computerized Procedure System must provide, at a minimum, a) Specification: access to design basis procedures, b) Monitoring: incorporation of real-time plant status, c) Advise: highlighting likely decision paths, and d) Reporting: logging conditions and actions taken. The CPS plays a critical role in overcoming the human factors that lead to accidents. At the same time it can be an essential tool in providing the information and automation to augment what humans do best, identify patterns and make associative leaps in the presence of ambiguous data. Timeliner and TaskGuide are examples of CPS that have evolved from projects in the aerospace industry. They illustrate certain common characteristics of a CPS, namely the knowledge base, user interface, and traceability features. The complexity and number of procedures for a current nuclear project has led to the development of two tools, the Power Generation Control System (PGCS) and the Online Procedure System (OLPS). Together, these systems address the knowledge-base and user interface aspects of a CPS and go a long way in addressing other areas. PGCS and OLPS contain full configuration management capabilities for procedures and the operating recipe. They include administrative functions for online and offline management of documents and data. Some lessons learned from this pair of programs developed by Invensys is the need for more integrated recording mechanisms. The future of CPS is likely to see higher integration of the document access, system status, decision support and logging capabilities. The CPS may evolve into the standard operational interface. Internet technologies that are common-place today have made the possibility of the Active Document a reality. The OPC Foundation is pursuing standards that may accelerate such developments. (authors)

  20. The Glittre-ADL test reflects functional performance measured by physical activities of daily living in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Manuela Karloh

    2016-01-01

    Full Text Available ABSTRACT Background The Glittre-ADL test (TGlittre is a valid and reliable test for the evaluation of functional capacity and involves multiple physical activities of daily living (PADL, which are known to be troublesome to patients with Chronic Obstructive Pulmonary Disease (COPD. However, it is still unknown if this test is also able to reflect the functional performance of patients with COPD. Objective To investigate whether the TGlittre reflects the functional performance of COPD patients and whether the necessary time to complete the TGlittre and the PADL varies according to disease severity. Method Thirty-eight patients with COPD (age 65, SD=7 years; forced expiratory volume in the first second 41.3, SD=15.2% predicted underwent anthropometric and lung function assessments and were submitted to the TGlittre and PADL measurement. Results TGlittre performance correlated significantly (p<0.05 with PADL variables, such as time sitting (r=0.50, walking (r=-0.46, number of steps taken (r=–0.53, walking movement intensity (r=–0.66, walking energy expenditure (r=-0.50, and total energy expenditure (r=–0.33. TGlittre performance was not significantly different in patients among the Global Initiative for COPD (GOLD spirometric stages, but walking and sitting time were significantly lower and greater, respectively, in severe and very severe patients compared to those with moderate disease (p<0.05. Conclusion The performance on the TGlittre correlates with walking and sitting time and other real life PADL measurements. The severity of the disease is associated with the differences in the level of physical activity in daily life more than in functional capacity.

  1. Analysis of Public Datasets for Wearable Fall Detection Systems.

    Science.gov (United States)

    Casilari, Eduardo; Santoyo-Ramón, José-Antonio; Cano-García, José-Manuel

    2017-06-27

    Due to the boom of wireless handheld devices such as smartwatches and smartphones, wearable Fall Detection Systems (FDSs) have become a major focus of attention among the research community during the last years. The effectiveness of a wearable FDS must be contrasted against a wide variety of measurements obtained from inertial sensors during the occurrence of falls and Activities of Daily Living (ADLs). In this regard, the access to public databases constitutes the basis for an open and systematic assessment of fall detection techniques. This paper reviews and appraises twelve existing available data repositories containing measurements of ADLs and emulated falls envisaged for the evaluation of fall detection algorithms in wearable FDSs. The analysis of the found datasets is performed in a comprehensive way, taking into account the multiple factors involved in the definition of the testbeds deployed for the generation of the mobility samples. The study of the traces brings to light the lack of a common experimental benchmarking procedure and, consequently, the large heterogeneity of the datasets from a number of perspectives (length and number of samples, typology of the emulated falls and ADLs, characteristics of the test subjects, features and positions of the sensors, etc.). Concerning this, the statistical analysis of the samples reveals the impact of the sensor range on the reliability of the traces. In addition, the study evidences the importance of the selection of the ADLs and the need of categorizing the ADLs depending on the intensity of the movements in order to evaluate the capability of a certain detection algorithm to discriminate falls from ADLs.

  2. Analysis of Public Datasets for Wearable Fall Detection Systems

    Directory of Open Access Journals (Sweden)

    Eduardo Casilari

    2017-06-01

    Full Text Available Due to the boom of wireless handheld devices such as smartwatches and smartphones, wearable Fall Detection Systems (FDSs have become a major focus of attention among the research community during the last years. The effectiveness of a wearable FDS must be contrasted against a wide variety of measurements obtained from inertial sensors during the occurrence of falls and Activities of Daily Living (ADLs. In this regard, the access to public databases constitutes the basis for an open and systematic assessment of fall detection techniques. This paper reviews and appraises twelve existing available data repositories containing measurements of ADLs and emulated falls envisaged for the evaluation of fall detection algorithms in wearable FDSs. The analysis of the found datasets is performed in a comprehensive way, taking into account the multiple factors involved in the definition of the testbeds deployed for the generation of the mobility samples. The study of the traces brings to light the lack of a common experimental benchmarking procedure and, consequently, the large heterogeneity of the datasets from a number of perspectives (length and number of samples, typology of the emulated falls and ADLs, characteristics of the test subjects, features and positions of the sensors, etc.. Concerning this, the statistical analysis of the samples reveals the impact of the sensor range on the reliability of the traces. In addition, the study evidences the importance of the selection of the ADLs and the need of categorizing the ADLs depending on the intensity of the movements in order to evaluate the capability of a certain detection algorithm to discriminate falls from ADLs.

  3. COPMA-III: a tool for developing effective computerised procedure systems

    International Nuclear Information System (INIS)

    Bisio, R.; Hulsund, J.E.; NiIsen, S.

    2001-01-01

    The management of complicated work processes is often described in terms of procedures. Traditionally, the way to instruct operators has been through paper-based procedure manuals. However, the availability of powerful computer technology has led to development of Computerised Procedures Systems, CPS. Such systems offer assistance to the operators in procedure execution, providing services like automatic control of plant conditions, record of executed instructions, indication of next instructions to execute, automatic execution of actions, etc. CPS can provide very useful support to control room operators in their task and contribute, to safer operation of complex plants. Their design and implementation are, however, not trivial tasks. Many factors must be taken into account, not the least the great variance in the environment in which a CPS should be integrated. Other considerations are the requirements to operators in a distributed environment where operators may be located in different geographical areas. A special case of multi-user environment is when different operators cooperate in executing the same procedure. CPSs must also be able to support different Human Computer Interfaces (HCIs) for different operators. Further, they must permit different levels of automation support, and different strategies to execute procedure, like sequential or parallel execution of instructions. In this report requirements, which we consider crucial for design of powerful CPSs, are discussed. The Halden Project has developed a system, COPMA-III, which meets these requirements through providing a core of basic CPS functionalities that can be customised into a target CPS. (Author)

  4. Cross-layer design of reconfigurable cyber-physical systems

    NARCIS (Netherlands)

    Masin, M.; Palumbo, F.; Myrhaug, H.; De Oliveira Filho, J.A.; Pastena, M.; Pelcat, M.; Raffo, L.; Regazzoni, F.; Sanchez, A.A.; Toffetti, A.; Torre, E. de la; Zedda, K.

    2017-01-01

    In the last few years, besides the concepts of embedded and interconnected systems, also the notion of Cyber-Physical Systems (CPS) has emerged: embedded computational collaborating devices, capable of sensing and controlling physical elements and, often, responding to humans. The continuous

  5. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Volume 121 Issue 2 April 2012 pp 273-285. Development of multimodel ensemble based district level medium range rainfall forecast system for Indian region .... 123 Issue 7 October 2014 pp 1637-1652. Forecasting of cyclone Viyaru and Phailin by NWP-based cyclone prediction system (CPS) of IMD – an evaluation.

  6. DEVELOPMENT OF WEARABLE HUMAN FALL DETECTION SYSTEM USING MULTILAYER PERCEPTRON NEURAL NETWORK

    Directory of Open Access Journals (Sweden)

    Hamideh Kerdegari

    2013-02-01

    Full Text Available This paper presents an accurate wearable fall detection system which can identify the occurrence of falls among elderly population. A waist worn tri-axial accelerometer was used to capture the movement signals of human body. A set of laboratory-based falls and activities of daily living (ADL were performed by volunteers with different physical characteristics. The collected acceleration patterns were classified precisely to fall and ADL using multilayer perceptron (MLP neural network. This work was resulted to a high accuracy wearable fall-detection system with the accuracy of 91.6%.

  7. A federation of simulations based on cellular automata in cyber-physical systems

    Directory of Open Access Journals (Sweden)

    Hoang Van Tran

    2016-02-01

    Full Text Available In cyber-physical system (CPS, cooperation between a variety of computational and physical elements usually poses difficulties to current modelling and simulation tools. Although much research has proposed to address those challenges, most solutions do not completely cover uncertain interactions in CPS. In this paper, we present a new approach to federate simulations for CPS. A federation is a combination of, and coordination between simulations upon a standard of communication. In addition, a mixed simulation is defined as several parallel simulations federated in a common time progress. Such simulations run on the models of physical systems, which are built based on cellular automata theory. The experimental results are performed on a federation of three simulations of forest fire spread, river pollution diffusion and wireless sensor network. The obtained results can be utilized to observe and predict the behaviours of physical systems in their interactions.

  8. Functionality of exopolysaccharides produced by lactic acid bacteria in an in vitro gastric system.

    Science.gov (United States)

    Mozzi, F; Gerbino, E; Font de Valdez, G; Torino, M I

    2009-07-01

    To evaluate whether slime-exopolysaccharides (EPS) or capsular-polysaccharide (CPS) production could protect the polymer-producing strains Streptococcus thermophilus CRL 1190 and Lactobacillus casei CRL 87 against the harsh conditions of an in vitro gastric system (GS). EPS stability on the GS was studied. An in vitro GS model containing human saliva and gastric juice was standardized. Polymer functionality on the cell viability and metabolic activity of the EPS-producing strains in the GS acidic conditions was evaluated. Two isogenic EPS/CPS deficient mutants were used for comparison. EPS or CPS conferred no significant protection on the cell viability of the studied strains after passage through the GS conditions. However, the phospho- and beta-galactosidase activities of the EPS(+) strains were higher than those of the EPS(-). Cytoplasmic alterations in the wild-type and mutant strains and partial degradation of both EPS were detected. The presence of EPS/CPS protected the metabolic activity of the assayed LAB strains, but had no effect on survival at low pH. The presence of EPS/CPS as well as polymer resistance to the harsh conditions of the human GS could impact positively in probiotic strains to exert their properties in the host.

  9. Corporate portal system at PAKS NPP, Hungary

    International Nuclear Information System (INIS)

    2016-01-01

    The new Corporate Portal System (CPS) of Paks NPP was launched in November 2006. The portal is based on one of the latest technologies, Plumtree Enterprise WEB 5.0. The main purpose of the installation of the new technology was to serve the working culture change, to give a platform to access all information and applications including the integrated process model used at the NPP. The new technology also supports those goals which were defined in the organization development programme: e.g. to improve internal communication with the establishment of communities of practice. Installation of the CPS has provided a powerful tool for knowledge management; it is possible to share and find all information through a controlled access in documents from various sources, to have links to people, portlets and different communities. Document management of the Paks NPP is supported by the integration of the Document 5 application, as the new Electronic Data Management System (EDMS) and the CPS. Depending on their access rights, all users of the CPS, through Microsoft Internet Explorer, can access technical, economic and human resources documents which are stored anywhere on the internal network (file servers, EDMS, old INRANET). The CPS is also accessible from the internet through a secure connection. The main concept is the integration of all applications to one platform and to help users to find all information they need. An access control list specifies which users and groups have access to an object (and what kind of access privileges they have such as read, select, edit, admin)

  10. Helene ve Güzel Helena Adlı Oyunların Konu Bakımından Karşılaştırılması

    OpenAIRE

    ZERENLER, Dilek

    2005-01-01

    Mitoloji her dönemde tiyatronun başvurduğu bir malzeme olmuştur. Esere kazandırdığı zenginlik,yarattığı düş gücüyle okura farklı bir dünya sunulmasını sağlar. Her yazar bu malzemeyi kendi çağının gereğine göre veya benimsediği dünya görüşü doğrultusunda yorumlar.Bu çalışmada MÖ 5. yüzyılda yaşayan Euripidesin Helene adlı oyunu ile 20. yüzyılın önemli yazarlarından Selahattin Batunun Güzel Helena adlı oyunu konu bakımından karşılaştırılarak her iki yazarın aynı efsaneyi ele alış biçimleri ve d...

  11. The impact of buprenorphine transdermal delivery system on activities of daily living among patients with chronic low back pain: an application of the international classification of functioning, disability and health.

    Science.gov (United States)

    Miller, Kate; Yarlas, Aaron; Wen, Warren; Dain, Bradley; Lynch, Shau Yu; Ripa, Steven R; Pergolizzi, Joseph V; Raffa, Robert

    2014-12-01

    The buprenorphine transdermal delivery system (BTDS) is indicated for reduction of pain in moderate to severe chronic low back pain (CLBP), which can affect patients' ability to perform routine activities of daily living (ADLs). This post hoc analysis of clinical trial data examines the impact of BTDS treatment on CLBP patients' ability to perform ADLs that relate to functioning with low back pain. Data are drawn from a multicenter, enriched enrollment, randomized, placebo-controlled, double-blind 12-week trial of BTDS for pain control among opioid-naive patients with moderate to severe CLBP. The 23 selected ADLs are those that (1) appear in the Low Back Pain Core Set of the International Classification of Functioning, Disability and Health and (2) link to the content of 3 patient-reported outcome instruments administered during the trial. Logistic regression models estimated the odds ratios (ORs) of BTDS patients' ability to perform each ADL at 12 weeks, controlling for baseline ability, relative to placebo. The ORs for 10 ADLs related to sleeping, lifting, bending, and working reached multiplicity-adjusted statistical significance and indicated a greater ability to perform ADLs among BTDS users than among the placebo group. These 10 ORs ranged from 1.9 (no physical health-related restrictions on the kind of work performed) to 2.4 (being able to sleep undisturbed by pain). These results suggest that for patients with moderate to severe CLBP, 12 weeks use of BTDS improves the ability to carry out certain ADLs related to sleeping, lifting, bending, and working.

  12. Efficient Large-Scale 2D Culture System for Human Induced Pluripotent Stem Cells and Differentiated Cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Shugo Tohyama

    2017-11-01

    Full Text Available Cardiac regenerative therapies utilizing human induced pluripotent stem cells (hiPSCs are hampered by ineffective large-scale culture. hiPSCs were cultured in multilayer culture plates (CPs with active gas ventilation (AGV, resulting in stable proliferation and pluripotency. Seeding of 1 × 106 hiPSCs per layer yielded 7.2 × 108 hiPSCs in 4-layer CPs and 1.7 × 109 hiPSCs in 10-layer CPs with pluripotency. hiPSCs were sequentially differentiated into cardiomyocytes (CMs in a two-dimensional (2D differentiation protocol. The efficiency of cardiac differentiation using 10-layer CPs with AGV was 66%–87%. Approximately 6.2–7.0 × 108 cells (4-layer and 1.5–2.8 × 109 cells (10-layer were obtained with AGV. After metabolic purification with glucose- and glutamine-depleted and lactate-supplemented media, a massive amount of purified CMs was prepared. Here, we present a scalable 2D culture system using multilayer CPs with AGV for hiPSC-derived CMs, which will facilitate clinical applications for severe heart failure in the near future.

  13. Interdisciplinary semantic model for managing the design of a steam-assisted gravity drainage tooling system

    Directory of Open Access Journals (Sweden)

    Michael Leitch

    2018-01-01

    Full Text Available Complex engineering systems often require extensive coordination between different expert areas in order to avoid costly design iterations and rework. Cyber-physics system (CPS engineering methods could provide valuable insights to help model these interactions and optimize the design of such systems. In this work, steam assisted gravity drainage (SAGD, a complex oil extraction process that requires deep understanding of several physical-chemical phenomena, is examined whereby the complexities and interdependencies of the system are explored. Based on an established unified feature modeling scheme, a software modeling framework is proposed to manage the design process of the production tools used for SAGD oil extraction. Applying CPS methods to unify complex phenomenon and engineering models, the proposed CPS model combines effective simulation with embedded knowledge of completion tooling design in order to optimize reservoir performance. The system design is expressed using graphical diagrams of the unified modelling language (UML convention. To demonstrate the capability of this system, a distributed research group is described, and their activities coordinated using the described CPS model.

  14. Towards a Resilience Metric Framework for Cyber-Physical Systems

    OpenAIRE

    Friedberg, Ivo; McLaughlin, Kieran; Smith, Paul; Wurzenberger, Markus

    2016-01-01

    Resilience is widely accepted as a desirable system property for cyber-physical systems. However, there are no metrics that can be used to measure the resilience of cyber-physical systems (CPS) while the multi-dimensional nature of performance in these systems is considered. In this work, we present first results towards a resilience metric framework. The key contributions of this framework are threefold: First, it allows to evaluate resilience with respect to different performance indicators...

  15. Medical cyber-physical systems: A survey.

    Science.gov (United States)

    Dey, Nilanjan; Ashour, Amira S; Shi, Fuqian; Fong, Simon James; Tavares, João Manuel R S

    2018-03-10

    Medical cyber-physical systems (MCPS) are healthcare critical integration of a network of medical devices. These systems are progressively used in hospitals to achieve a continuous high-quality healthcare. The MCPS design faces numerous challenges, including inoperability, security/privacy, and high assurance in the system software. In the current work, the infrastructure of the cyber-physical systems (CPS) are reviewed and discussed. This article enriched the researches of the networked Medical Device (MD) systems to increase the efficiency and safety of the healthcare. It also can assist the specialists of medical device to overcome crucial issues related to medical devices, and the challenges facing the design of the medical device's network. The concept of the social networking and its security along with the concept of the wireless sensor networks (WSNs) are addressed. Afterward, the CPS systems and platforms have been established, where more focus was directed toward CPS-based healthcare. The big data framework of CPSs is also included.

  16. Cyber physical system based on resilient ICT

    Science.gov (United States)

    Iwatsuki, Katsumi

    2016-02-01

    While development of science and technology has built up the sophisticated civilized society, it has also resulted in quite a few disadvantages in global environment and human society. The common recognition has been increasingly shared worldwide on sustainable development society attaching greater importance to the symbiotic relationship with nature and social ethics. After the East Japan Great Earthquake, it is indispensable for sustainable social development to enhance capacity of resistance and restoration of society against natural disaster, so called "resilient society". Our society consists of various Cyber Physical Systems (CPSs) that make up the physical systems by fusing with an Information Communication Technology (ICT). We describe the proposed structure of CPS in order to realize resilient society. The configuration of resilient CPS consisting of ICT and physical system is discussed to introduce "autonomous, distributed, and cooperative" structure, where subsystems of ICT and physical system are simultaneously coordinated and cooperated with Business Continuity Planning (BCP) engine, respectively. We show the disaster response information system and energy network as examples of BCP engine and resilient CPS, respectively. We also propose the structure and key technology of resilient ICT.

  17. Toward Co-Design of Autonomous Aerospace Cyber-Physical Systems

    Science.gov (United States)

    Bradley, Justin M.

    Modern vehicles are equipped with a complex suite of computing (cyber) and electromechanical (physical) systems. Holistic design, modeling, and optimization of such Cyber-Physical Systems (CPS) requires new techniques capable of integrated analysis across the full CPS. This dissertations introduces two methods for balancing cyber and physical resources in a step toward holistic co-design of CPS. First, an ordinary differential equation model abstraction of controller sampling rate is developed and added to the equations of motion of a physical system to form a holistic discrete-time-varying linear system representing the CPS controller. Using feedback control, this cyber effector, sampling rate, is then co-regulated alongside physical effectors in response to physical system tracking error. This technique is applied to a spring-mass-damper, inverted pendulum, and finally to attitude control of a small satellite (CubeSat). Additionally, two new controllers for discrete-time-varying systems are introduced; a gain-scheduled discrete-time linear regulator (DLQR) in which DLQR gains are scheduled over time-varying sampling rates, and a forward-propagation Riccati-based (FPRB) controller. The FPRB CPS controller shows promise in balancing cyber and physical resources. Second, we propose a cost function of cyber and physical parameters to optimize an Unmanned Aircraft System (UAS) trajectory for a pipeline surveillance mission. Optimization parameters are UAV velocity and mission-critical surveillance task execution rate. Metrics for pipeline image information, energy, cyber utilization, and time comprise the cost function and Pareto fronts are analyzed to gain insight into cyber and physical tradeoffs for mission success. Finally, the cost function is optimized using numerical methods, and results from several cost weightings and Pareto front analyses are tabulated. We show that increased mission success can be achieved by considering both cyber and physical parameters

  18. The Development of Enterprise Systems based on Cyber- Physical Systems Principles

    Directory of Open Access Journals (Sweden)

    Ioan Ştefan Sacală

    2014-12-01

    Full Text Available Research in the area of Cyber-Physical Systems (CPS and Internet of Things (IoT become, in the last 3 years a priority for both research entities and companies. Implementing Enterprise Systems based on the two paradigms is focused on merging real and virtual objects and thus deals with an increased degree of complexity. The aim of the present paper is to discuss an Enterprise Architecture and a Framework based on the integration of CPS and IoT technologies within Enterprise Systems. An important aspect is related to process mining implemented in two focus areas: the ability to generate business processes from data acquired from sensors and the ability to integrate sensor acquired data with existing business processes.

  19. CPS Trawl Life History Length Frequency Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Length distribution of a subset of individuals from a species (mainly non-target) caught during SWFSC-FRD fishery independent trawl surveys of coastal pelagic...

  20. CPS Trawl Life History Specimen Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Individual specimens measured (weight in grams and length in mm) and sexed from mainly targeted species caught during SWFSC-FRD fishery independent trawl surveys of...

  1. Evaluating IEEE 802.15.4 for Cyber-Physical Systems

    Directory of Open Access Journals (Sweden)

    Vinel Alexey

    2011-01-01

    Full Text Available With rapid advancements in sensing, networking, and computing technologies, recent years have witnessed the emergence of cyber-physical systems (CPS in a broad range of application domains. CPS is a new class of engineered systems that features the integration of computation, communications, and control. In contrast to general-purpose computing systems, many cyber-physical applications are safety critical. These applications impose considerable requirements on quality of service (QoS of the employed networking infrastruture. Since IEEE 802.15.4 has been widely considered as a suitable protocol for CPS over wireless sensor and actuator networks, it is of vital importance to evaluate its performance extensively. Serving for this purpose, this paper will analyze the performance of IEEE 802.15.4 standard operating in different modes respectively. Extensive simulations have been conducted to examine how network QoS will be impacted by some critical parameters. The results are presented and analyzed, which provide some useful insights for network parameter configuration and optimization for CPS design.

  2. The relationships between menthol cigarette preference and state tobacco control policies on smoking behaviors of young adult smokers in the 2006-07 Tobacco Use Supplements to the Current Population Surveys (TUS CPS).

    Science.gov (United States)

    Ahijevych, Karen; Ford, Jodi

    2010-12-01

    To examine relationships between the preference for menthol cigarettes and young adult smoking behaviors, including the extent to which state tobacco control policies moderate these relationships. Cross-sectional design using secondary data from the 2006-07 Tobacco Use Supplements to the Current Population Surveys (TUS CPS) surveys appended with 2006 state-policy data. United States nationally representative survey. A total of 2241 young adult daily smokers and 688 young adult non-daily smokers. The two dependent variables of smoking behaviors were smoking first cigarette within 30 minutes of waking (TTF) and number of cigarettes smoked per day (cpd). Primary independent variables included menthol brand preference and state tobacco control policies (youth access laws, clean indoor air laws and cigarette excise taxes), adjusting for controls. Among daily smokers, there were no significant associations between menthol brand preference and TTF or cpd. However, lower educational attainment, not being in the labor force and the lack of home smoking rules were associated positively with shorter TTF, being white and the lack of home smoking rules were associated positively with cpd. Among daily smokers, state excise taxes were associated negatively with higher cpd. Among non-daily smokers, menthol brand preference was associated positively with shorter TTF, but associations did not vary with state tobacco control policies. Menthol brand preference was not associated significantly with cpd, but male gender, unmarried status and the lack of home smoking rules were associated positively with greater cpd among non-daily smokers. Young adult non-daily smokers who preferred menthol cigarettes were significantly more dependent than those who preferred non-menthol cigarettes, as shown through the shorter TTF. Associations between menthol brand preference and smoking behaviors did not vary with state tobacco control policies. © 2010 The Authors, Addiction © 2010 Society for the

  3. Deficiency of RgpG Causes Major Defects in Cell Division and Biofilm Formation, and Deficiency of LytR-CpsA-Psr Family Proteins Leads to Accumulation of Cell Wall Antigens in Culture Medium by Streptococcus mutans.

    Science.gov (United States)

    De, Arpan; Liao, Sumei; Bitoun, Jacob P; Roth, Randy; Beatty, Wandy L; Wu, Hui; Wen, Zezhang T

    2017-09-01

    Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis pathway, were constructed by allelic exchange. The rgpG deficiency had no effect on growth rate but caused major defects in cell division and altered cell morphology. Unlike the coccoid wild type, the rgpG mutant existed primarily in chains of swollen, "squarish" dividing cells. Deficiency of rgpG also causes significant reduction in biofilm formation ( P mutans plays a critical role in cell division and biofilm formation and that BrpA and Psr may be responsible for attachment of cell wall antigens to the cell envelope. IMPORTANCE Streptococcus mutans , a major etiological agent of human dental caries, produces rhamnose-glucose polysaccharide (RGP) as the major cell wall antigen. This study provides direct evidence that deficiency of RgpG, the first enzyme of the RGP biosynthesis pathway, caused major defects in cell division and morphology and reduced biofilm formation by S. mutans , indicative of a significant role of RGP in cell division and biofilm formation in S. mutans These results are novel not only in S. mutans , but also other streptococci that produce RGP. This study also shows that the LytR-CpsA-Psr family proteins BrpA and Psr in S. mutans are involved in attachment of RGP and probably other cell wall glycopolymers to the peptidoglycan. In addition, the results also suggest that BrpA and Psr may play a direct role in cell division and biofilm formation in S. mutans This study reveals new potential targets to develop anticaries therapeutics. Copyright © 2017 American Society for Microbiology.

  4. Computational intelligence for decision support in cyber-physical systems

    CERN Document Server

    Ali, A; Riaz, Zahid

    2014-01-01

    This book is dedicated to applied computational intelligence and soft computing techniques with special reference to decision support in Cyber Physical Systems (CPS), where the physical as well as the communication segment of the networked entities interact with each other. The joint dynamics of such systems result in a complex combination of computers, software, networks and physical processes all combined to establish a process flow at system level. This volume provides the audience with an in-depth vision about how to ensure dependability, safety, security and efficiency in real time by making use of computational intelligence in various CPS applications ranging from the nano-world to large scale wide area systems of systems. Key application areas include healthcare, transportation, energy, process control and robotics where intelligent decision support has key significance in establishing dynamic, ever-changing and high confidence future technologies. A recommended text for graduate students and researche...

  5. Meaningful participation for children in the Dutch child protection system : A critical analysis of relevant provisions in policy documents

    NARCIS (Netherlands)

    Bouma, Helen; López López, Mónica; Knorth, Erik J.; Grietens, Hans

    2018-01-01

    Policymakers are increasingly focusing on the participation of children in the child protection system (CPS). However, research shows that actual practice still needs to be improved. Embedding children’s participation in legislation and policy documents is one important prerequisite for achieving

  6. Context- and Template-Based Compression for Efficient Management of Data Models in Resource-Constrained Systems.

    Science.gov (United States)

    Macho, Jorge Berzosa; Montón, Luis Gardeazabal; Rodriguez, Roberto Cortiñas

    2017-08-01

    The Cyber Physical Systems (CPS) paradigm is based on the deployment of interconnected heterogeneous devices and systems, so interoperability is at the heart of any CPS architecture design. In this sense, the adoption of standard and generic data formats for data representation and communication, e.g., XML or JSON, effectively addresses the interoperability problem among heterogeneous systems. Nevertheless, the verbosity of those standard data formats usually demands system resources that might suppose an overload for the resource-constrained devices that are typically deployed in CPS. In this work we present Context- and Template-based Compression (CTC), a data compression approach targeted to resource-constrained devices, which allows reducing the resources needed to transmit, store and process data models. Additionally, we provide a benchmark evaluation and comparison with current implementations of the Efficient XML Interchange (EXI) processor, which is promoted by the World Wide Web Consortium (W3C), and it is the most prominent XML compression mechanism nowadays. Interestingly, the results from the evaluation show that CTC outperforms EXI implementations in terms of memory usage and speed, keeping similar compression rates. As a conclusion, CTC is shown to be a good candidate for managing standard data model representation formats in CPS composed of resource-constrained devices.

  7. Towards Prescriptive Analytics in Cyber-Physical Systems

    DEFF Research Database (Denmark)

    Siksnys, Laurynas

    in an intelligent and well-coordinated manner to secure and optimize a physical process, e.g., electricity flow in the power grid. In today’s CPSs, the control is typically automated, but the planning is solely performed by humans. Unfortunately, it is intractable and infeasible for humans to plan every action...... agent software system. At the CPS level, the contributions include the definition of PrescriptiveCPS, according to which it is the system of interacting physical and cyber (sub-)systems. Here, the cyber system consists of hierarchically organized inter-connected agents, collectively managing instances...... solving capability allowing to formulate optimization problems using SQL-like queries and to solve them “inside a database”, (4) a real-time data management architecture for processing instances of flexibility and prescription models under (soft or hard) timing constraints, and (5) a graphical user...

  8. COMMUNITY BASED HOME ENERGY MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    Muhammad Adnan Aziz

    2017-05-01

    Full Text Available In a Smart Grid (SG scenario, domestic consumers can gain cost reduction benefit by scheduling their Appliance Activation Time (AAT towards the slots of low charge. Minimization in cost is essential in Home Energy Management Systems (HEMS to induce consumers acceptance for power scheduling to accommodate for a Demand Response (DR at peak hours. Despite the fact that many algorithms address the power scheduling for HEMS, community based optimization has not been the focus. This paper presents an algorithm that targets the minimization of energy costs of whole community while keeping a low Peak to Average Ratio (PAR and smooth Power Usage Pattern (PUP. Objective of cost reduction is accomplished by finding most favorable AAT by Particle Swarm Optimization (PSO in conjunction with Inclined Block Rate (IBR approach and Circular Price Shift (CPS. Simulated numerical results demonstrate the effectiveness of CPS to assist the merger of PSO & IBR to enhance the reduction/stability of PAR and cost reduction.

  9. Optimization and Control of Cyber-Physical Vehicle Systems.

    Science.gov (United States)

    Bradley, Justin M; Atkins, Ella M

    2015-09-11

    A cyber-physical system (CPS) is composed of tightly-integrated computation, communication and physical elements. Medical devices, buildings, mobile devices, robots, transportation and energy systems can benefit from CPS co-design and optimization techniques. Cyber-physical vehicle systems (CPVSs) are rapidly advancing due to progress in real-time computing, control and artificial intelligence. Multidisciplinary or multi-objective design optimization maximizes CPS efficiency, capability and safety, while online regulation enables the vehicle to be responsive to disturbances, modeling errors and uncertainties. CPVS optimization occurs at design-time and at run-time. This paper surveys the run-time cooperative optimization or co-optimization of cyber and physical systems, which have historically been considered separately. A run-time CPVS is also cooperatively regulated or co-regulated when cyber and physical resources are utilized in a manner that is responsive to both cyber and physical system requirements. This paper surveys research that considers both cyber and physical resources in co-optimization and co-regulation schemes with applications to mobile robotic and vehicle systems. Time-varying sampling patterns, sensor scheduling, anytime control, feedback scheduling, task and motion planning and resource sharing are examined.

  10. Optimization and Control of Cyber-Physical Vehicle Systems

    Directory of Open Access Journals (Sweden)

    Justin M. Bradley

    2015-09-01

    Full Text Available A cyber-physical system (CPS is composed of tightly-integrated computation, communication and physical elements. Medical devices, buildings, mobile devices, robots, transportation and energy systems can benefit from CPS co-design and optimization techniques. Cyber-physical vehicle systems (CPVSs are rapidly advancing due to progress in real-time computing, control and artificial intelligence. Multidisciplinary or multi-objective design optimization maximizes CPS efficiency, capability and safety, while online regulation enables the vehicle to be responsive to disturbances, modeling errors and uncertainties. CPVS optimization occurs at design-time and at run-time. This paper surveys the run-time cooperative optimization or co-optimization of cyber and physical systems, which have historically been considered separately. A run-time CPVS is also cooperatively regulated or co-regulated when cyber and physical resources are utilized in a manner that is responsive to both cyber and physical system requirements. This paper surveys research that considers both cyber and physical resources in co-optimization and co-regulation schemes with applications to mobile robotic and vehicle systems. Time-varying sampling patterns, sensor scheduling, anytime control, feedback scheduling, task and motion planning and resource sharing are examined.

  11. Meaningful participation for children in the Dutch child protection system: A critical analysis of relevant provisions in policy documents.

    Science.gov (United States)

    Bouma, Helen; López López, Mónica; Knorth, Erik J; Grietens, Hans

    2018-05-01

    Policymakers are increasingly focusing on the participation of children in the child protection system (CPS). However, research shows that actual practice still needs to be improved. Embedding children's participation in legislation and policy documents is one important prerequisite for achieving meaningful participation in child protection practice. In this study, the participation of children in the Dutch CPS under the new Youth Act 2015 is critically analyzed. National legislation and policy documents were studied using a model of "meaningful participation" based on article 12 of the UNCRC. Results show that the idea of children's participation is deeply embedded in the current Dutch CPS. However, Dutch policy documents do not fully cover the three dimensions of what is considered to be meaningful participation for children: informing, hearing, and involving. Furthermore, children's participation differs among the organizations included in the child protection chain. A clear overall policy concerning the participation of children in the Dutch CPS is lacking. The conclusions of this critical analysis of policy documents and the framework of meaningful participation presented may provide a basis for the embedding of meaningful participation for children in child protection systems of other countries. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Sustainable Development of Heritage Areas: Towards Cyber-Physical Systems Integration in Extant Heritage Buildings and Planning Conservation

    Directory of Open Access Journals (Sweden)

    Laila Mohamed Khodeir

    2017-03-01

    Full Text Available Although architectural heritage reflects the evolution of human civilization throughout history, nevertheless, civilized and social changes of heritage areas in many countries led to their degradation. Historical building management and planning conservation raise two important issues: the restoration and improvement of historical areas features and adopting a framework of sustainable development in heritage regions. Recently a number of processes have arose to aid in the aforementioned problems, namely the heritage building information modelling (HBIM and the  cyber-physical systems approach (CPS, where the latter is believed to  achieve great potentials hereby integrating virtual models and physical construction and  enabling bidirectional coordination. Since HBIM has recently been investigated through a number of recent research and application, the aim of this paper is to explore the potentials offered by the CPS, to move from 3D content model to bi-dimensional coordination for achieving efficient management of built heritage. To tackle the objective of this paper, firstly, a review of the BIM use in the field of cultural heritage  was undergone, Secondly, reporting the existing BIM/HBIM platforms, analyzing cyber-physical systems integration in extant heritage buildings and in planning conservation were performed. Results of this paper took the form of detailed comparative analysis between both CPS and HBIM, which could guide decision makers working in the field of heritage buildings management, in addition to shedding light on the main potentials of the emerging CPS.

  13. The Impact of Classroom Performance System-Based Instruction with Peer Instruction upon Student Achievement and Motivation in Eighth Grade Math Students

    Science.gov (United States)

    Allison, Tracy Michelle Hunter

    2012-01-01

    The researcher employed two designs to address the research question for this particular study. This quasi-experimental non-equivalent control group study compared the math achievement of 92 eighth grade students who received Classroom Performance System (CPS)-based instruction using Peer Instruction (PI) to 76 eighth grade students who received…

  14. Project to replace the control and protection system at the WWR-K research reactor

    International Nuclear Information System (INIS)

    Chakrov, P.; Arinkin, F.; Gizatulin, Sh.; Schultz, R.; Mote, N.; Alldred, K.

    2008-01-01

    The WWR-K is a tank-type, light water moderated and cooled multipurpose research reactor with a nominal power rating of 6 MW and a peak thermal neutron flux of over 1014 n/cm 2 s. The reactor is operated by the Institute of Nuclear Physics of the National Nuclear Center of the Republic of Kazakhstan (INP), and is located at Alatau, near Almaty, the largest city in Kazakhstan. The reactor was commissioned in 1967 with a power rating of 10 MW, then shut down between 1988 and 1998 while seismic safety upgrades were completed. Currently, INP is undertaking the planning and technical work to allow the reactor to be converted from HEU fuel with a U-235 content of 36% to LEU fuel with a U-235 content of 19.7%. The reactor has an important role in Kazakhstan, and is producing isotopes for medical and industrial uses, providing material testing services and neutron activation analysis. Replacement of reactor control and protection system (CPS) is a part of the wider program of the reactor modifications related to its conversion from HEU to LEU fuel, supported by the US Department of Energy, the Nuclear Threat Initiative and the Kazakhstan government. The program includes development of a new LEU fuel assembly design and re-configuration of the reactor core, with change in number and positions of the control rods, which requires modification of the CPS. Furthermore, replacement of the existing instrumentation, some of which is 40 years old, will improve reactor safety, bring the CPS up to current international standards, and provide an upgraded control interface. The existing CPS at the WWR-K relies to a large extent on old designs of detectors and electronic equipment that are no longer in production and the system as a whole does not meet the necessary standards for prolonged operation of the reactor. Consequently, the Kazakhstan Atomic Energy Committee (KAEC), the nuclear regulatory body of Kazakhstan has mandated that the project for conversion of the WWR-K to use LEU

  15. A Neural Networks Based Operation Guidance System for Procedure Presentation and Validation

    International Nuclear Information System (INIS)

    Seung, Kun Mo; Lee, Seung Jun; Seong, Poong Hyun

    2006-01-01

    In this paper, a neural network based operator support system is proposed to reduce operator's errors in abnormal situations in nuclear power plants (NPPs). There are many complicated situations, in which regular and suitable operations should be done by operators accordingly. In order to regulate and validate operators' operations, it is necessary to develop an operator support system which includes computer based procedures with the functions for operation validation. Many computerized procedures systems (CPS) have been recently developed. Focusing on the human machine interface (HMI) design and procedures' computerization, most of CPSs used various methodologies to enhance system's convenience, reliability and accessibility. Other than only showing procedures, the proposed system integrates a simple CPS and an operation validation system (OVS) by using artificial neural network (ANN) for operational permission and quantitative evaluation

  16. Integrated modelling of the glass-iron-clay system

    Energy Technology Data Exchange (ETDEWEB)

    Bildstein, O

    2007-01-15

    This report summarizes the results of integrated calculations on the near-field evolution in the VHLW/steel/bentonite/clay system. The calculations of the near-field evolution include different components: the vitrified waste packages, the steel container, the bentonite-based EBS (optional), the EDZ and the geological medium. Coupled reaction-transport (X-T) is used to simulate the corrosion of the steel canister and the glass alteration phase in presence of corrosion products (CPs), looking at mass transfer for chemical elements, especially iron and silica, pH, and porosity change. Calculations as performed give actual parameters for PA calculations: rate of glass alteration (through the calculated pH) as a function of time, extension of altered zone for iron-clay interactions with their own transport parameters, nature of CPs, effect on porosity distribution. According to the operational model currently used at the CEA and the calculations performed on the glass-iron-clay system, the alteration rate of glass and the evolution of the system strongly depend on the timing of CPs saturation with respect to silica sorption. The fate of silica which can be sorbed or precipitate is crucial to the lifetime of glass and to the overall evolution of the system. The other process that might influence the glass is the porosity decrease due to the precipitation of CPs and silica rich phases. However, it is difficult to assign a safety functions to clogging. It is scarcely observed in experiments, either because the conditions are not met for clogging or because the timescale of experiments does not allow for observable clogging. Moreover, the effect of mechanical stress in the NF has to be accounted for in the assessment of the effect of porosity changes. (author)

  17. Integrated modelling of the glass-iron-clay system

    International Nuclear Information System (INIS)

    Bildstein, O.

    2007-01-01

    This report summarizes the results of integrated calculations on the near-field evolution in the VHLW/steel/bentonite/clay system. The calculations of the near-field evolution include different components: the vitrified waste packages, the steel container, the bentonite-based EBS (optional), the EDZ and the geological medium. Coupled reaction-transport (X-T) is used to simulate the corrosion of the steel canister and the glass alteration phase in presence of corrosion products (CPs), looking at mass transfer for chemical elements, especially iron and silica, pH, and porosity change. Calculations as performed give actual parameters for PA calculations: rate of glass alteration (through the calculated pH) as a function of time, extension of altered zone for iron-clay interactions with their own transport parameters, nature of CPs, effect on porosity distribution. According to the operational model currently used at the CEA and the calculations performed on the glass-iron-clay system, the alteration rate of glass and the evolution of the system strongly depend on the timing of CPs saturation with respect to silica sorption. The fate of silica which can be sorbed or precipitate is crucial to the lifetime of glass and to the overall evolution of the system. The other process that might influence the glass is the porosity decrease due to the precipitation of CPs and silica rich phases. However, it is difficult to assign a safety functions to clogging. It is scarcely observed in experiments, either because the conditions are not met for clogging or because the timescale of experiments does not allow for observable clogging. Moreover, the effect of mechanical stress in the NF has to be accounted for in the assessment of the effect of porosity changes. (author)

  18. Kamel Daoud'un “Meursault Karşı Soruşturma” Adlı Romanında Yeniden Yazma ve Söyleşimcilik

    Directory of Open Access Journals (Sweden)

    Tülin KARTAL GÜNGÖR

    2017-09-01

    Full Text Available Kaynağını postmodernizm ve yapısökümcülükten alan ve Mikhail Bakhtin’in söyleşimcilik düşüncesinden hareketle, 1960 yılında Julia Kristeva tarafından kuramlaştırılan “metinlerarasılık, bütün metinlerin, öncekilerini yeniden ürettiği noktasında birleşir. Albert Camus’nun 1942 yılında yayımlanan Yabancı adlı romanını kendisine çıkış noktası olarak ele alan Kamel Daoud, 2014 yılında yayımlanan Meursault Karşı Soruşturma adlı romanında kültürel ve kimlik farklılıklarına dikkat çeker. Yazar, içinde bulunduğu dönemin tarihi ve kurgusal gerçeklikleriyle Camus'nün romandaki gerçeklikleri iç içe geçiren ve metinlerarası özellikler taşıyan bir yapıt ortaya koyar. Camus’nün romanında Meursault'un öldürdüğü Arab'ın kardeşi olduğunu anladığımız anlatıcı, Camus’nün yapıtını yeniden ele alma isteğinden, karşı öneriler sunmaktan ve bugünkü Cezayir'in günlük hayatından bahseder. Yapıtta sıklıkla Doğu-Batı imgesi, bu iki kültürün karşılaşması, sentezi, uyumu/ uyumsuzluğu, genellikle de çatışmasına rastlanır. Roman hem benzerlik bildiren ifadelerle, hem de sürekli farklılıklardan söz eden söylemlerle örülüdür. Bu çalışmada, yazarın, metinlerarası ilişkiler ve postmodernizmde dikkat çeken yeniden yazma ve söyleşimcilik yoluyla, yapıtına nasıl yeni bir varoluş kazandırdığını göstermeye çalışacağız. Ayrıca, romanında durum ve kahramanlar arasında var olan ortak noktaları dönüştürülerek yeniden yazan yazarın, günümüz toplumunun karmaşık ve çoksesli dünyasını nasıl yansıttığını, Doğu ve Batı kültürü arasında nasıl bir söyleşimsel dil geliştirdiğini vurgulamaya çalışacağız.

  19. Mechanical deployment system on aries an autonomous mobile robot

    International Nuclear Information System (INIS)

    Rocheleau, D.N.

    1995-01-01

    ARIES (Autonomous Robotic Inspection Experimental System) is under development for the Department of Energy (DOE) to survey and inspect drums containing low-level radioactive waste stored in warehouses at DOE facilities. This paper focuses on the mechanical deployment system-referred to as the camera positioning system (CPS)-used in the project. The CPS is used for positioning four identical but separate camera packages consisting of vision cameras and other required sensors such as bar-code readers and light stripe projectors. The CPS is attached to the top of a mobile robot and consists of two mechanisms. The first is a lift mechanism composed of 5 interlocking rail-elements which starts from a retracted position and extends upward to simultaneously position 3 separate camera packages to inspect the top three drums of a column of four drums. The second is a parallelogram special case Grashof four-bar mechanism which is used for positioning a camera package on drums on the floor. Both mechanisms are the subject of this paper, where the lift mechanism is discussed in detail

  20. The Past, Present and Future of Cyber-Physical Systems: A Focus on Models

    Directory of Open Access Journals (Sweden)

    Edward A. Lee

    2015-02-01

    Full Text Available This paper is about better engineering of cyber-physical systems (CPSs through better models. Deterministic models have historically proven extremely useful and arguably form the kingpin of the industrial revolution and the digital and information technology revolutions. Key deterministic models that have proven successful include differential equations, synchronous digital logic and single-threaded imperative programs. Cyber-physical systems, however, combine these models in such a way that determinism is not preserved. Two projects show that deterministic CPS models with faithful physical realizations are possible and practical. The first project is PRET, which shows that the timing precision of synchronous digital logic can be practically made available at the software level of abstraction. The second project is Ptides (programming temporally-integrated distributed embedded systems, which shows that deterministic models for distributed cyber-physical systems have practical faithful realizations. These projects are existence proofs that deterministic CPS models are possible and practical.

  1. The past, present and future of cyber-physical systems: a focus on models.

    Science.gov (United States)

    Lee, Edward A

    2015-02-26

    This paper is about better engineering of cyber-physical systems (CPSs) through better models. Deterministic models have historically proven extremely useful and arguably form the kingpin of the industrial revolution and the digital and information technology revolutions. Key deterministic models that have proven successful include differential equations, synchronous digital logic and single-threaded imperative programs. Cyber-physical systems, however, combine these models in such a way that determinism is not preserved. Two projects show that deterministic CPS models with faithful physical realizations are possible and practical. The first project is PRET, which shows that the timing precision of synchronous digital logic can be practically made available at the software level of abstraction. The second project is Ptides (programming temporally-integrated distributed embedded systems), which shows that deterministic models for distributed cyber-physical systems have practical faithful realizations. These projects are existence proofs that deterministic CPS models are possible and practical.

  2. Model-implementation fidelity in cyber physical system design

    CERN Document Server

    Fabre, Christian

    2017-01-01

    This book puts in focus various techniques for checking modeling fidelity of Cyber Physical Systems (CPS), with respect to the physical world they represent. The authors' present modeling and analysis techniques representing different communities, from very different angles, discuss their possible interactions, and discuss the commonalities and differences between their practices. Coverage includes model driven development, resource-driven development, statistical analysis, proofs of simulator implementation, compiler construction, power/temperature modeling of digital devices, high-level performance analysis, and code/device certification. Several industrial contexts are covered, including modeling of computing and communication, proof architectures models and statistical based validation techniques. Addresses CPS design problems such as cross-application interference, parsimonious modeling, and trustful code production Describes solutions, such as simulation for extra-functional properties, extension of cod...

  3. Future Interoperability of Camp Protection Systems (FICAPS)

    Science.gov (United States)

    Caron, Sylvie; Gündisch, Rainer; Marchand, Alain; Stahl, Karl-Hermann

    2013-05-01

    The FICAPS Project has been established as a Project of the European Defence Agency based on an initiative of Germany and France. Goal of this Project was to derive Guidelines, which by a proper implementation in future developments improve Camp Protection Systems (CPS) by enabling and improving interoperability between Camp Protection Systems and its Equipments of different Nations involved in multinational missions. These Guidelines shall allow for: • Real-time information exchange between equipments and systems of different suppliers and nations (even via SatCom), • Quick and easy replacement of equipments (even of different Nations) at run-time in the field by means of plug and play capability, thus lowering the operational and logistic costs and making the system highly available, • Enhancement of system capabilities (open and modular systems) by adding new equipment with new capabilities (just plug-in, automatic adjustment of the HMI Human Machine Interface) without costly and time consuming validation and test on system level (validation and test can be done on Equipment level), Four scenarios have been identified to summarize the interoperability requirements from an operational viewpoint. To prove the definitions given in the Guideline Document, a French and a German Demonstration System, based on existing national assets, were realized. Demonstrations, showing the capabilities given by the defined interoperability requirements with respect to the operational scenarios, were performed. Demonstrations included remote control of a CPS by another CPS, remote sensor control (Electro-Optic/InfraRed EO/IR) and remote effector control. This capability can be applied to extend the protection area or to protect distant infrastructural assets Demonstrations have been performed. The required interoperability functionality was shown successfully. Even if the focus of the FICAPS project was on camp protection, the solution found is also appropriate for other

  4. RAMI analysis for DEMO HCPB blanket concept cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Dongiovanni, Danilo N., E-mail: danilo.dongiovanni@enea.it [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati (Italy); Pinna, Tonio [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati (Italy); Carloni, Dario [KIT, Institute of Neutron Physics and Reactor Technology (INR) – KIT (Germany)

    2015-10-15

    Highlights: • RAMI (reliability, availability, maintainability and inspectability) preliminary assessment for HCPB blanket concept cooling system. • Reliability block diagram (RBD) modeling and analysis for HCPB primary heat transfer system (PHTS), coolant purification system (CPS), pressure control system (PCS), and secondary cooling system. • Sensitivity analysis on system availability performance. • Failure models and repair models estimated on the base of data from the ENEA fusion component failure rate database (FCFRDB). - Abstract: A preliminary RAMI (reliability, availability, maintainability and inspectability) assessment for the HCPB (helium cooled pebble bed) blanket cooling system based on currently available design for DEMO fusion power plant is presented. The following sub-systems were considered in the analysis: blanket modules, primary cooling loop including pipework and steam generators lines, pressure control system (PCS), coolant purification system (CPS) and secondary cooling system. For PCS and CPS systems an extrapolation from ITER Test Blanket Module corresponding systems was used as reference design in the analysis. Helium cooled pebble bed (HCPB) system reliability block diagrams (RBD) models were implemented taking into account: system reliability-wise configuration, operating schedule currently foreseen for DEMO, maintenance schedule and plant evolution schedule as well as failure and corrective maintenance models. A simulation of plant activity was then performed on implemented RBDs to estimate plant availability performance on a mission time of 30 calendar years. The resulting availability performance was finally compared to availability goals previously proposed for DEMO plant by a panel of experts. The study suggests that inherent availability goals proposed for DEMO PHTS system and Tokamak auxiliaries are potentially achievable for the primary loop of the HCPB concept cooling system, but not for the secondary loop. A

  5. The SafeCOP ECSEL Project: Safe Cooperating Cyber-Physical Systems Using Wireless Communication

    DEFF Research Database (Denmark)

    Pop, Paul; Scholle, Detlef; Hansson, Hans

    2016-01-01

    communication, multiple stakeholders, dynamic system definitions (openness), and unpredictable operating environments. SafeCOP will provide an approach to the safety assurance of CO-CPS, enabling thus their certification and development. The project will define a runtime manager architecture for runtime...... detection of abnormal behaviour, triggering if needed a safe degraded mode. SafeCOP will also develop methods and tools, which will be used to produce safety assurance evidence needed to certify cooperative functions. SafeCOP will extend current wireless technologies to ensure safe and secure cooperation......This paper presents an overview of the ECSEL project entitled "Safe Cooperating Cyber-Physical Systems using Wireless Communication" (SafeCOP), which runs during the period 2016 -- 2019. SafeCOP targets safety-related Cooperating Cyber-Physical Systems (CO-CPS) characterised by use of wireless...

  6. Operating The Central Process Systems At Glenn Research Center

    Science.gov (United States)

    Weiler, Carly P.

    2004-01-01

    As a research facility, the Glenn Research Center (GRC) trusts and expects all the systems, controlling their facilities to run properly and efficiently in order for their research and operations to occur proficiently and on time. While there are many systems necessary for the operations at GRC, one of those most vital systems is the Central Process Systems (CPS). The CPS controls operations used by GRC's wind tunnels, propulsion systems lab, engine components research lab, and compressor, turbine and combustor test cells. Used widely throughout the lab, it operates equipment such as exhausters, chillers, cooling towers, compressors, dehydrators, and other such equipment. Through parameters such as pressure, temperature, speed, flow, etc., it performs its primary operations on the major systems of Electrical Dispatch (ED), Central Air Dispatch (CAD), Central Air Equipment Building (CAEB), and Engine Research Building (ERB). In order for the CPS to continue its operations at Glenn, a new contract must be awarded. Consequently, one of my primary responsibilities was assisting the Source Evaluation Board (SEB) with the process of awarding the recertification contract of the CPS. The job of the SEB was to evaluate the proposals of the contract bidders and then to present their findings to the Source Selecting Official (SSO). Before the evaluations began, the Center Director established the level of the competition. For this contract, the competition was limited to those companies classified as a small, disadvantaged business. After an industry briefing that explained to qualified companies the CPS and type of work required, each of the interested companies then submitted proposals addressing three components: Mission Suitability, Cost, and Past Performance. These proposals were based off the Statement of Work (SOW) written by the SEB. After companies submitted their proposals, the SEB reviewed all three components and then presented their results to the SSO. While the

  7. Method for calculating the forces and deformations in the fast reactor fuel assembly accounting for the effects of reactor control system elements and shutdown

    International Nuclear Information System (INIS)

    Likhachev, Yu.I.; Vashlyaev, Yu.N.; Kravchenko, I.N.

    1980-01-01

    Methods for calculating deformations and interaction forces of heat-generating assemblies (HGA) of fast reactor core with account for the effect of control and protection system (CPS) elements at the reactor operation and change of interaction efforts between HGA at the reactor shutdown, are described. The results of testing the suggested methods on example of estimate of HGA behaviour of the BN-350 reactor are presented. For estimating the effect of CPS elements on HGA bending the sector model has been used. It is assumed that HGA deformation inside each sector is independent of HGA deformation of other sectors. A higher calculation accuracy is attained by means of laying out of sectors into regions of preferable influence of emergency protection elements and compensating packets. When determining deformation and interaction efforts between HGA caused by temperature change in the course of shutdown it is supposed that the HGA deformation is purely elastic. The methods described are realized in the form of ABRI-CPS and ABRI-HOL programs written in FORTRAN for the BESM-6 computer. The results of HGA calculations of the BN-350 reactor core show that CPS elements decrease contact efforts in the middle of the central packet, increase contact efforts in the peak of the central packet, increase contact efforts in the peaks of packets from the eight row to the periphery and increase contact efforts in the middles of packets from the 5th to 9th row [ru

  8. Self-Adaptive Strategy Based on Fuzzy Control Systems for Improving Performance in Wireless Sensors Networks

    Directory of Open Access Journals (Sweden)

    Vicente Hernández Díaz

    2015-09-01

    Full Text Available The solutions to cope with new challenges that societies have to face nowadays involve providing smarter daily systems. To achieve this, technology has to evolve and leverage physical systems automatic interactions, with less human intervention. Technological paradigms like Internet of Things (IoT and Cyber-Physical Systems (CPS are providing reference models, architectures, approaches and tools that are to support cross-domain solutions. Thus, CPS based solutions will be applied in different application domains like e-Health, Smart Grid, Smart Transportation and so on, to assure the expected response from a complex system that relies on the smooth interaction and cooperation of diverse networked physical systems. The Wireless Sensors Networks (WSN are a well-known wireless technology that are part of large CPS. The WSN aims at monitoring a physical system, object, (e.g., the environmental condition of a cargo container, and relaying data to the targeted processing element. The WSN communication reliability, as well as a restrained energy consumption, are expected features in a WSN. This paper shows the results obtained in a real WSN deployment, based on SunSPOT nodes, which carries out a fuzzy based control strategy to improve energy consumption while keeping communication reliability and computational resources usage among boundaries.

  9. Self-Adaptive Strategy Based on Fuzzy Control Systems for Improving Performance in Wireless Sensors Networks.

    Science.gov (United States)

    Hernández Díaz, Vicente; Martínez, José-Fernán; Lucas Martínez, Néstor; del Toro, Raúl M

    2015-09-18

    The solutions to cope with new challenges that societies have to face nowadays involve providing smarter daily systems. To achieve this, technology has to evolve and leverage physical systems automatic interactions, with less human intervention. Technological paradigms like Internet of Things (IoT) and Cyber-Physical Systems (CPS) are providing reference models, architectures, approaches and tools that are to support cross-domain solutions. Thus, CPS based solutions will be applied in different application domains like e-Health, Smart Grid, Smart Transportation and so on, to assure the expected response from a complex system that relies on the smooth interaction and cooperation of diverse networked physical systems. The Wireless Sensors Networks (WSN) are a well-known wireless technology that are part of large CPS. The WSN aims at monitoring a physical system, object, (e.g., the environmental condition of a cargo container), and relaying data to the targeted processing element. The WSN communication reliability, as well as a restrained energy consumption, are expected features in a WSN. This paper shows the results obtained in a real WSN deployment, based on SunSPOT nodes, which carries out a fuzzy based control strategy to improve energy consumption while keeping communication reliability and computational resources usage among boundaries.

  10. Assistive system for people with Apraxia using a Markov decision process.

    Science.gov (United States)

    Jean-Baptiste, Emilie M D; Russell, Martin; Rothstein, Pia

    2014-01-01

    CogWatch is an assistive system to re-train stroke survivors suffering from Apraxia or Action Disorganization Syndrome (AADS) to complete activities of daily living (ADLs). This paper describes the approach to real-time planning based on a Markov Decision Process (MDP), and demonstrates its ability to improve task's performance via user simulation. The paper concludes with a discussion of the remaining challenges and future enhancements.

  11. Airborne Collision Avoidance System as a Cyber-Physical System

    Directory of Open Access Journals (Sweden)

    Andrei C. NAE

    2015-12-01

    Full Text Available In this paper the key concepts of ITS - Intelligent Transport Systems, CPS - Cyber-Physical Systems and SM - Smart Mobility are defined and correlated with the need for ACAS – Airborne Collision Avoidance System, as the last resort safety net and indispensable ingredient in civil aviation. Smart Mobility is addressed from a Cyber Physical-Systems perspective, detailing some of the elements that this entails. Here we consider the Air Transportations System of the future as a Cyber-Physical System and analyze the implications of doing so from different perspectives. The objective is to introduce a 4D collision avoidance shield technology which forms a last resort safety net technology for the next generation air transport (2050 and beyond. The new system will represent a step change over the performance of current technology. As conclusions, the benefits of implementing Transport Cyber-Physical Systems are discussed, as well as what this would require for future deployment.

  12. Earthquake Forecasting System in Italy

    Science.gov (United States)

    Falcone, G.; Marzocchi, W.; Murru, M.; Taroni, M.; Faenza, L.

    2017-12-01

    In Italy, after the 2009 L'Aquila earthquake, a procedure was developed for gathering and disseminating authoritative information about the time dependence of seismic hazard to help communities prepare for a potentially destructive earthquake. The most striking time dependency of the earthquake occurrence process is the time clustering, which is particularly pronounced in time windows of days and weeks. The Operational Earthquake Forecasting (OEF) system that is developed at the Seismic Hazard Center (Centro di Pericolosità Sismica, CPS) of the Istituto Nazionale di Geofisica e Vulcanologia (INGV) is the authoritative source of seismic hazard information for Italian Civil Protection. The philosophy of the system rests on a few basic concepts: transparency, reproducibility, and testability. In particular, the transparent, reproducible, and testable earthquake forecasting system developed at CPS is based on ensemble modeling and on a rigorous testing phase. Such phase is carried out according to the guidance proposed by the Collaboratory for the Study of Earthquake Predictability (CSEP, international infrastructure aimed at evaluating quantitatively earthquake prediction and forecast models through purely prospective and reproducible experiments). In the OEF system, the two most popular short-term models were used: the Epidemic-Type Aftershock Sequences (ETAS) and the Short-Term Earthquake Probabilities (STEP). Here, we report the results from OEF's 24hour earthquake forecasting during the main phases of the 2016-2017 sequence occurred in Central Apennines (Italy).

  13. Modélisation et simulation haut-niveau de micro-systèmes électromécaniques pour le prototypage virtuel multi-physique en SystemC-AMS

    OpenAIRE

    Vernay, Benoit

    2016-01-01

    Embedded systems have evolved to more complex assemblies, called Cyber-Physical Systems (CPS), mostly operating through networks and tightly interacting with the environment. As actuators or sensors, micro-electromechanical systems (MEMS) are essential elements in these systems where they are integrated along with control and signal processing units. Designing such solutions requires a multi-domain approach like virtual prototyping. Based on system-level models, this technique allows to antic...

  14. Differential Haematobia irritans infestation levels in beef cattle raised in silvopastoral and conventional pasture systems.

    Science.gov (United States)

    de S Oliveira, Márcia Cristina; Nicodemo, Maria Luiza F; Gusmão, Marcos R; Pezzopane, José Ricardo M; Bilhassi, Talita B; Santana, Clarissa H; Gonçalves, Thuane C; Rabelo, Márcio D; Giglioti, Rodrigo

    2017-11-15

    The use of silvopastoral systems (SPS) can be a good alternative to reduce the environmental impacts of livestock breeding in Brazil. One of the reasons for its scarce adoption is the lack of information on health and productivity of cattle raised under these conditions. The experiment reported here was designed to compare the infestation by external parasites - the cattle tick (Rhipicephalus microplus), horn fly (Haematobia irritans), and larvae of the botfly (Dermatobia hominis) - in beef cattle raised in a SPS and a conventional pasture system (CPS), evaluated for 24 months. Data on air and soil temperature, solar radiation, wind incidence and water balance were used to characterize the SPS and CPS. R. microplus adult females and D. hominis larvae were counted on the body of each animal to determine the parasites burdens, but we did not find significant differences between the two systems. Horn flies counts on animals' body, and analysis of the horn fly and its pupal parasitoids associated with the dung pats were obtained in the two systems. Horn fly infestation was significantly lower (p=0.01) in the SPS (13.17±3.46) in comparison with the CPS (24.02±4.43). In SPS and CPS, respectively, the mean densities of pupae of H. irritansin dung pats were 9.8 and 10.7; the mean density of adults of H. irritans, 3.7 and 3.5; and the density of its pupal parasitoids were 20.5 and 5.4. The effect of production system was significant (p<0.05) only for the occurrence of pupal parasitoids of the horn fly, where the greatest occurrences of these natural enemies were in the SPS. These data indicate that natural enemies were able to control, at least partially, the horn fly populations in the cattle. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. “Konuşma” Adlı Küçürek Öyküde Kendilik Sorunsalları Selhood Problematics in the Minimal Story Named "Speech"

    Directory of Open Access Journals (Sweden)

    Yeliz AKAR

    2012-12-01

    vortex of selfhood problematics. Küçürek öykü, gözlemlenebilen şey’in insan ruhunda ve bilincinde içselleşen izdüşümleri sonrası yazınsallaşır. Sınırlı sayıda sözle düşünsel söylemleri aktaran küçürek öykü, insana ait değer dünyasının metinleşmesidir. Bu metinleri varoluşçu söylemle örüntüleyen Ferit Edgü, küçürek öykülerinde kendilik değerleriyle iletişime geçen insanın yaşadığı süreçlere gönderme yapar. Ferit Edgü anlatıları arasında önemli bir yere sahip olan küçürek öykü, az sayıda sözcükle toplumsal ve bireysel söylemleri metinleştirir. Bu metinleşmenin bir göstergesi olan “Konuşma” adlı küçürek öykü, kendilik değerleri yok olan bir insanın tükenişini imler. Öyküde varoluşsal bir sorgulamanın eşiğinde kalan insanın trajik sürecine yer verilir. Yaşam sürecindeki sorgulamalarıyla varlık sancısı yaşayan anlatı kişisi, kendi yaralarına sıkışarak içindeki yaşatıcı özü tamamıyla yok eder ve kendilik sorunsalı yaşar. Güçlü kendilik sorunsallarıyla yaşatıcı açılımlarını kaybeden anlatı kişisi, kendilik değerlerini çürütür. Bu sorunsallarla yaşam sürecinde yaşam refleksini yitiren anlatı kişisinin yaşadığı ruhsal ve bilinçsel yıkımı gösteren küçürek öykü, kendilik değerlerini yokluğa götüren süreçlere de gönderme yapar. Öyküde iki anlatı kişisine yer verilir. Birinci anlatı kişisi, öykünün birinci öznesidir ve yaralarıyla yaşamının soğuduğunu düşünür. İkinci anlatı kişisi ise, birinci anlatı kişisinin söylemlerini belirginleştirme amaçlı öyküde yer edinen yardımcı öznedir. Birinci özne ve ikinci özne arasındaki söylemler, birinci öznenin içinde bulunduğu ruh halini imler. Çalışmanın temel izleğini veren “Konuşma” adlı küçürek öyküde, kendilik sorunsallarının girdabında yaşamı soğuyan bir insanın söylemlerine yer verilir.

  16. Faruk Nafiz Çamlıbel’in Suda Halkalar Adlı Eserinde Su İmajları ve Benzetmeler Water Images and Metaphors in Suda Halkalar Which Faruk Nafiz Çamlıbel’s Work

    Directory of Open Access Journals (Sweden)

    Hüseyin DOĞRAMACIOĞLU

    2012-09-01

    Full Text Available Suda Halkalar (Circles in Water which the poetry book of Faruk Nafiz Çamlıbel, has not been translated into the Latin alphabet to the present day. The images of the water and metaphors which used in this work brought new connotations and approaches to the Turkish poetry. The images of the water in the poetry book are used instead of the poet's soul and dreams sometimes. These images are thought with poet’s darling and sometimes are used as a background. The poetformed the images of the water in his poem sadly. There are the poetand his darling in these tables. The images of the water and thedreams of the poet form the background of the poem. The backgroundsin this poem are repeated as a leitmotiv. Visuality and individualitybecomes important feature in these tables created by the poet. Themetaphors in the work created differently from classical Turkish poetry.These metaphors brought a new meaning to the poem. The poem basedon the intellectual grounds via metaphors. This can be considered asone of the significant achievements of Turkish poetry. We can see thatthe past remembered and desired both in poetry and metaphors bypessimistic feeling. In this respect the past affects the poet's dreamscombining with a sense of mourning, water images and metaphors inpoetry. The metaphors can be grouped as imaginary, visual andstrongly poetic ground. The feelings of pessimism and sadness arepredominant in these metaphors. The images and metaphors used bythe poet can be considered as an improvement for Turkish poetry. It isthe first research done on Suda Halkalar (Circles in Water will help tobetter understand and identify Çamlıbel’s aspect of poetry and literaryline. Faruk Nafiz Çamlıbel’in Suda Halkalar adlı şiir kitabı günümüze kadar Latin harflerine aktarılmamıştır. Bu eserde kullanılan su imajları ve benzetmeler Türk şiirine yeni yaklaşımlar ve çağrışımlar getirmiştir. Eserdeki su imajları bazen şairin ruhu ve hayalleri

  17. Extracting aerobic system dynamics during unsupervised activities of daily living using wearable sensor machine learning models.

    Science.gov (United States)

    Beltrame, Thomas; Amelard, Robert; Wong, Alexander; Hughson, Richard L

    2018-02-01

    Physical activity levels are related through algorithms to the energetic demand, with no information regarding the integrity of the multiple physiological systems involved in the energetic supply. Longitudinal analysis of the oxygen uptake (V̇o 2 ) by wearable sensors in realistic settings might permit development of a practical tool for the study of the longitudinal aerobic system dynamics (i.e., V̇o 2 kinetics). This study evaluated aerobic system dynamics based on predicted V̇o 2 data obtained from wearable sensors during unsupervised activities of daily living (μADL). Thirteen healthy men performed a laboratory-controlled moderate exercise protocol and were monitored for ≈6 h/day for 4 days (μADL data). Variables derived from hip accelerometer (ACC HIP ), heart rate monitor, and respiratory bands during μADL were extracted and processed by a validated random forest regression model to predict V̇o 2 . The aerobic system analysis was based on the frequency-domain analysis of ACC HIP and predicted V̇o 2 data obtained during μADL. Optimal samples for frequency domain analysis (constrained to ≤0.01 Hz) were selected when ACC HIP was higher than 0.05 g at a given frequency (i.e., participants were active). The temporal characteristics of predicted V̇o 2 data during μADL correlated with the temporal characteristics of measured V̇o 2 data during laboratory-controlled protocol ([Formula: see text] = 0.82, P system dynamics can be investigated during unsupervised activities of daily living by wearable sensors. Although speculative, these algorithms have the potential to be incorporated into wearable systems for early detection of changes in health status in realistic environments by detecting changes in aerobic response dynamics. NEW & NOTEWORTHY The early detection of subclinical aerobic system impairments might be indicative of impaired physiological reserves that impact the capacity for physical activity. This study is the first to use wearable

  18. A Promising Combo Gene Delivery System Developed from (3-Aminopropyl)triethoxysilane-Modified Iron Oxide Nanoparticles and Cationic Polymers

    International Nuclear Information System (INIS)

    Zhang Zubin; Song Lina; Dong Jinlai; Guo Dawei; Du Xiaolin; Cao Biyin; Zhang Yu; Gu Ning; Mao Xinliang

    2013-01-01

    (3-Aminopropyl)triethoxysilane-modified iron oxide nanoparticles (APTES-IONPs) have been evaluated for various biomedical applications, including medical imaging and drug delivery. Cationic polymers (CPs) such as Lipofectamine and TurboFect are widely used for research in gene delivery, but their toxicity and low in vivo efficiency limited their further application. In the present study, we synthesized water-soluble APTES-IONPs and developed a combo gene delivery system based on APTES-IONPs and CPs. This system significantly increased gene-binding capacity, protected genes from degradation, and improved gene transfection efficiency for DNA and siRNA in both adherent and suspension cells. Because of its great biocompatibility, high gene-carrying ability, and very low cytotoxicity, this combo gene delivery system will be expected for a wide application, and it might provide a new method for gene therapy.

  19. A Promising Combo Gene Delivery System Developed from (3-Aminopropyl)triethoxysilane-Modified Iron Oxide Nanoparticles and Cationic Polymers

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Zubin [Soochow University, Cyrus Tang Hematology Center (China); Song Lina; Dong Jinlai; Guo Dawei [School of Biological Science and Medical Engineering, Southeast University, State Key Laboratory of Bioelectronics and Jiangsu Key Laboratory for Biomaterials and Devices (China); Du Xiaolin; Cao Biyin [Soochow University, Cyrus Tang Hematology Center (China); Zhang Yu; Gu Ning [School of Biological Science and Medical Engineering, Southeast University, State Key Laboratory of Bioelectronics and Jiangsu Key Laboratory for Biomaterials and Devices (China); Mao Xinliang, E-mail: xinliangmao@suda.edu.cn [Soochow University, Cyrus Tang Hematology Center (China)

    2013-05-15

    (3-Aminopropyl)triethoxysilane-modified iron oxide nanoparticles (APTES-IONPs) have been evaluated for various biomedical applications, including medical imaging and drug delivery. Cationic polymers (CPs) such as Lipofectamine and TurboFect are widely used for research in gene delivery, but their toxicity and low in vivo efficiency limited their further application. In the present study, we synthesized water-soluble APTES-IONPs and developed a combo gene delivery system based on APTES-IONPs and CPs. This system significantly increased gene-binding capacity, protected genes from degradation, and improved gene transfection efficiency for DNA and siRNA in both adherent and suspension cells. Because of its great biocompatibility, high gene-carrying ability, and very low cytotoxicity, this combo gene delivery system will be expected for a wide application, and it might provide a new method for gene therapy.

  20. Distributed Dimensionality Reduction Fusion Estimation with Communication Delays in Cyber-Physical Systems

    OpenAIRE

    Chen, Bo; Ho, Daniel W. C.; Hu, Guoqiang; Yu, Li

    2018-01-01

    This paper studies the distributed dimensionality reduction fusion estimation problem with communication delays for a class of cyber-physical systems (CPSs). The raw measurements are preprocessed in each sink node to obtain the local optimal estimate (LOE) of a CPS, and the compressed LOE under dimensionality reduction encounters with communication delays during the transmission. Under this case, a mathematical model with compensation strategy is proposed to characterize the dimensionality re...

  1. Use of a dynamic in vitro attachment and invasion system (DIVAS) to determine influence of growth rate on invasion of respiratory epithelial cells by group B Streptococcus.

    Science.gov (United States)

    Malin, G; Paoletti, L C

    2001-11-06

    Expression of capsular polysaccharide (CPS) and some surface proteins by group B Streptococcus (GBS) is regulated by growth rate. We hypothesized that precise control of GBS growth, and thus surface-expressed components, could modulate the ability of GBS to invade eukaryotic cells. To test this hypothesis, a dynamic in vitro attachment and invasion system (DIVAS) was developed that combines the advantages of bacterial growth in continuous culture with tissue culture. Tissue culture flasks were modified with inlet and outlet ports to permit perfusion of GBS. Encapsulated type III GBS strains M781 and COH1 and strains COH1-11 and COH1-13 (transposon mutants of COH1 that express an asialo CPS or are acapsular, respectively) were grown in continuous culture in a chemically defined medium at fast mass doubling time (t(d) = 1.8 h) and slow (t(d) = 11 h) growth rates, conditions previously shown to induce and repress, respectively, type III CPS expression. Encapsulated GBS strains invaded A549 respiratory epithelial cells 20- to 700-fold better at the fast than at the slow growth rate, suggesting a role for CPS. However, unencapsulated GBS were also invasive but only when cultured at the fast growth rate, which indicates that GBS invasion is independent of CPS expression and can be regulated by growth rate. Growth rate-dependent invasion occurred when GBS was grown in continuous culture under glucose-defined, thiamine-defined, and undefined nutrient limitations. These results suggest a growth rate-dependent regulation of GBS pathogenesis and demonstrate the usefulness of DIVAS as a tool in studies of host-microbe interactions.

  2. A Decentralized Compositional Framework for Dependable Decision Process in Self-Managed Cyber Physical Systems

    Directory of Open Access Journals (Sweden)

    Peng Zhou

    2017-11-01

    Full Text Available Cyber Physical Systems (CPSs need to interact with the changeable environment under various interferences. To provide continuous and high quality services, a self-managed CPS should automatically reconstruct itself to adapt to these changes and recover from failures. Such dynamic adaptation behavior introduces systemic challenges for CPS design, advice evaluation and decision process arrangement. In this paper, a formal compositional framework is proposed to systematically improve the dependability of the decision process. To guarantee the consistent observation of event orders for causal reasoning, this work first proposes a relative time-based method to improve the composability and compositionality of the timing property of events. Based on the relative time solution, a formal reference framework is introduced for self-managed CPSs, which includes a compositional FSM-based actor model (subsystems of CPS, actor-based advice and runtime decomposable decisions. To simplify self-management, a self-similar recursive actor interface is proposed for decision (actor composition. We provide constraints and seven patterns for the composition of reliability and process time requirements. Further, two decentralized decision process strategies are proposed based on our framework, and we compare the reliability with the static strategy and the centralized processing strategy. The simulation results show that the one-order feedback strategy has high reliability, scalability and stability against the complexity of decision and random failure. This paper also shows a way to simplify the evaluation for dynamic system by improving the composability and compositionality of the subsystem.

  3. Halveti-Şâbânî Şeyhi Mustafa Kemâleddîn Bekrî ve Hediyyetü’l-Ahbâb Adlı Eseri

    Directory of Open Access Journals (Sweden)

    Halim Gül

    2013-03-01

    Full Text Available AbstractThis article studies the life and woks of Kemaleddin Bekrî, who affiliated himself to Khalvati-Shabani Sheikh Abdullatîf b. Hüsameddîn el-Halebî, and who was growed up under Abd al-Ghani al-Nabulsi’s control. His work “Hadiyyat al-Ahbab fi ma li’l-Khalveti min al-Şuruti va’l-Adab”, which explains the conditions and rules of “khalvet” was also studied. The work consists of preface, eight parts and an epilogue and all parts examined in detail.ÖzetBu makalede, Abdülganî Nablusî’nin (ö.1143/1730 gözetiminde yetişen, halvetî-Şabânî şeyhi Abdullatîf b. Hüsameddîn el-Halebî’ye intisap eden Mustafa Kemaleddin Bekrî’nin hayatı ve eserleri incelenmiştir. Bu çerçevede onun tasavvufi bir kavram olan halvetin âdab ve şartlarını izah eden “Hediyyetü’l ahbâb fî mâ li’l-halveti mine’ş-şurûti ve’l-âdâb” adlı risalesinin incelenmesi ve değerlendirmesi üzerinde durulmuştur. Söz konusu eser, mukaddime sekiz bölüm ve bir hatimeden oluşmaktadır.Le Shaykh Khalwatî-Sha‘bânî Mustafâ Kamâl al-Dîn Bakrî et son Traité qui s’intitule Hadiyya al-ahbâbRésuméDans cet article, on va étudier d’abord la vie et les œuvres du Shaykh Khalwatî-Sha‘bânî Mustafâ Kamâl al-Dîn Bakrî qui a été éduqué par le célèbre soufi ‘Abd al-Ghanî Nablûsî (m. 1143/1730 et a été initié par ‘Abd al-Latîf b. Husâm al-Dîn al-Halabî. Puis, plus particulièrement, on va analyser son traité qui s’intitule ‘Hadiyya al-ahbâb fî mâ li’l-khalwatî min al-shurût wa’l-âdâb’. Ce traité – qui a été composé de dix-huit chapitres et d’une conclusion – étudie les convenances et les conditions de la retraite spirituelle, khalwa, une des notions soufies importantes

  4. [Assessment of cognitive function, emotions and activities of daily living in patients with multiple system atrophy].

    Science.gov (United States)

    Song, Dong-dong; Yu, Ying-xin; Dong, Qing-wen; Zhang, Hai-ling; Liu, Jian-guo; Liu, Qi; Yu, Jian; Qi, Xiao-kun

    2013-07-02

    To explore the cognitive function, emotional status and activities of daily living in patients with multiple system atrophy (MSA). Thirty-two MSA patients and 38 healthy controls from October 2009 to November 2012 were recruited from our hospital. Their cognitive function, emotional status and activities of daily living were assessed. Cognitive function was assessed by Montreal cognitive assessment (MoCA) and mini-mental state examination (MMSE); emotional status by self-rating depression scale (SDS) and self-rating anxiety scale (SAS); daily living and activities by activities of daily living scale (ADL). Data analysis was performed with SPSS 19.0. And the results were presented as the mean ± standard deviation. Comparison of means was performed with independent sample t test. And Pearson's correlation test was used for correlation analysis. A P-value memory of the MSA group were significantly lower than those of the control group (P < 0.05). A negative correlation existed between the scores of MoCA and MMSE with disease duration (P < 0.01). There was a positive correlation between the scores of SDS and SAS with ADL and disease duration (P < 0.05). And the relationship was significant between the scores of SDS and SAS (P < 0.01). A positive correlation existed between scores of ADL with disease duration (P < 0.05). MSA patients have certain degrees of cognitive impairment, emotion disorders and impaired ADL. Cognitive impairment in MSA patients may be more common than previously. Furthermore, the clinical features of cognitive impairment in these patients may have some clinical values for references.

  5. Unsupervised machine-learning method for improving the performance of ambulatory fall-detection systems

    Directory of Open Access Journals (Sweden)

    Yuwono Mitchell

    2012-02-01

    Full Text Available Abstract Background Falls can cause trauma, disability and death among older people. Ambulatory accelerometer devices are currently capable of detecting falls in a controlled environment. However, research suggests that most current approaches can tend to have insufficient sensitivity and specificity in non-laboratory environments, in part because impacts can be experienced as part of ordinary daily living activities. Method We used a waist-worn wireless tri-axial accelerometer combined with digital signal processing, clustering and neural network classifiers. The method includes the application of Discrete Wavelet Transform, Regrouping Particle Swarm Optimization, Gaussian Distribution of Clustered Knowledge and an ensemble of classifiers including a multilayer perceptron and Augmented Radial Basis Function (ARBF neural networks. Results Preliminary testing with 8 healthy individuals in a home environment yields 98.6% sensitivity to falls and 99.6% specificity for routine Activities of Daily Living (ADL data. Single ARB and MLP classifiers were compared with a combined classifier. The combined classifier offers the greatest sensitivity, with a slight reduction in specificity for routine ADL and an increased specificity for exercise activities. In preliminary tests, the approach achieves 100% sensitivity on in-group falls, 97.65% on out-group falls, 99.33% specificity on routine ADL, and 96.59% specificity on exercise ADL. Conclusion The pre-processing and feature-extraction steps appear to simplify the signal while successfully extracting the essential features that are required to characterize a fall. The results suggest this combination of classifiers can perform better than MLP alone. Preliminary testing suggests these methods may be useful for researchers who are attempting to improve the performance of ambulatory fall-detection systems.

  6. Model documentation, Coal Market Module of the National Energy Modeling System

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the National Energy Modeling System`s (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 1998 (AEO98). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM`s two submodules. These are the Coal Production Submodule (CPS) and the Coal Distribution Submodule (CDS). CMM provides annual forecasts of prices, production, and consumption of coal for NEMS. In general, the CDS integrates the supply inputs from the CPS to satisfy demands for coal from exogenous demand models. The international area of the CDS forecasts annual world coal trade flows from major supply to major demand regions and provides annual forecasts of US coal exports for input to NEMS. Specifically, the CDS receives minemouth prices produced by the CPS, demand and other exogenous inputs from other NEMS components, and provides delivered coal prices and quantities to the NEMS economic sectors and regions.

  7. Micro view system (Toshiba)

    International Nuclear Information System (INIS)

    Tanaka, Takeshi; Kimata, Shinichi; Hirosawa, Koshichiro

    1981-01-01

    Digital processing of nuclear medical images consists of inputting the image, the process of adding adjustments, processing the image to meet diagnostic purposes, and storing this information. Discussion is made on the input of analog information transferred from a gamma camera, inputting the image in numeral matrix, number and size of image elements, modification processes, processing and display of the original data thus obtained, image processing of these data for medicine and storage of the information. The digital processing of nuclear medical images could be done satisfactorily with information of 10 kCPS in 64 x 64 (or 128 x 128) image elements in 16 bit frame mode. The personal computer M223 Mark II (SORD) was selected because it satisfied these requirements, and a system allowing image display was developed. (Kaihara, S.)

  8. The impact of a Classroom Performance System on learning gains in a biology course for science majors

    Science.gov (United States)

    Marin, Nilo Eric

    This study was conducted to determine if the use of the technology known as Classroom Performance System (CPS), specifically referred to as "Clickers", improves the learning gains of students enrolled in a biology course for science majors. CPS is one of a group of developing technologies adapted for providing feedback in the classroom using a learner-centered approach. It supports and facilitates discussion among students and between them and teachers, and provides for participation by passive students. Advocates, influenced by constructivist theories, claim increased academic achievement. In science teaching, the results have been mixed, but there is some evidence of improvements in conceptual understanding. The study employed a pretest-posttest, non-equivalent groups experimental design. The sample consisted of 226 participants in six sections of a college biology course at a large community college in South Florida with two instructors trained in the use of clickers. Each instructor randomly selected their sections into CPS (treatment) and non-CPS (control) groups. All participants filled out a survey that included demographic data at the beginning of the semester. The treatment group used clicker questions throughout, with discussions as necessary, whereas the control groups answered the same questions as quizzes, similarly engaging in discussion where necessary. The learning gains were assessed on a pre/post-test basis. The average learning gains, defined as the actual gain divided by the possible gain, were slightly better in the treatment group than in the control group, but the difference was statistically non-significant. An Analysis of Covariance (ANCOVA) statistic with pretest scores as the covariate was conducted to test for significant differences between the treatment and control groups on the posttest. A second ANCOVA was used to determine the significance of differences between the treatment and control groups on the posttest scores, after

  9. Modelo de gestão da tecnologia e do conhecimento para a integração de sistemas físico-cibernéticos (CPS aos processos logísticos das empresas

    Directory of Open Access Journals (Sweden)

    Diógenes Marcelo Cassiano Coriguazi

    2017-01-01

    Full Text Available The increasing needs for business efficiency improvement generates demands for new technologies. Such demands expand to logistics processes and the cyber-physical systems are the new trends to put these processes in a competitive level. For the implementation effectiveness of these new technologies it is need to develop a management model, for both technology and knowledge, looking for a lasting implementation, which can be disseminated through all corporation. The aim of this paper is to propose a technology and knowledge management model to support the integration of cyber-physical systems to the firms logistics processes. The proposed model aims to facilitate and speed up the cyber-physical systems integration to the firms logistics processes, such as material and information flows, by the technology and knowledge management, allowing the firms to monitor their performance improvement, sustaining a competitive advantage.

  10. Enforcing Availability in Failure-Aware Communicating Systems

    DEFF Research Database (Denmark)

    López-Acosta, Hugo-Andrés; Nielson, Flemming; Nielson, Hanne Riis

    2016-01-01

    Choreographic programming is a programming-language design approach that drives error-safe protocol development in distributed systems. Motivated by challenging scenarios in Cyber-Physical Systems (CPS), we study how choreographic programming can cater for dynamic infrastructures where...... the availability of components may change at runtime. We introduce the Global Quality Calculus (GCq), a process calculus featuring novel operators for multiparty, partial and collective communications; we provide a type discipline that controls how partial communications refer only to available components; and we...

  11. Safe Cooperating Cyber-Physical Systems using Wireless Communication

    DEFF Research Database (Denmark)

    Pop, Paul; Scholle, Detlef; Sljivo, Irfan

    2017-01-01

    detection of abnormal behaviour, triggering if needed a safe degraded mode. SafeCOP will also develop methods and tools, which will be used to produce safety assurance evidence needed to certify cooperative functions. SafeCOP will extend current wireless technologies to ensure safe and secure cooperation......This paper presents an overview of the ECSEL project entitled ―Safe Cooperating Cyber-Physical Systems using Wireless Communication‖ (SafeCOP), which runs during the period 2016–2019. SafeCOP targets safety-related Cooperating Cyber-Physical Systems (CO-CPS) characterised by use of wireless...

  12. Examining Child Welfare Decisions and Services for Asian-Canadian Versus White-Canadian Children and Families in the Child Welfare System.

    Science.gov (United States)

    Lee, Barbara; Fuller-Thomson, Esme; Fallon, Barbara; Black, Tara; Trocmé, Nico

    2017-05-01

    Using administrative child welfare data from the Ontario Child Abuse and Neglect Data System (OCANDS), this study compared the profiles of Asian-Canadian and White-Canadian children and families that experienced a case closure after an investigation instead of being transferred to ongoing child protection services (CPS). Child protection investigations involving Asian-Canadian and White-Canadian children and families that were transferred to ongoing CPS presented a different profile of case characteristics and caregiver and child clinical needs. Asian-Canadian children and families received ongoing CPS for over a month longer than White-Canadian children and families and were less likely (odds ratio [ OR] = 0.39) to be reinvestigated for any form of maltreatment-related concerns within 1 year after case closure. It appears that child protection investigations involving Asian-Canadian children and families are less likely to be closed prematurely than White-Canadian children and families, and the child protection system may be meeting the needs of Asian-Canadian communities. Alternatively, it is possible there is unaccounted biases that may be reflective of systemic problem of discriminative practices in the child protection system. Further research is needed to explore this phenomenon.

  13. Applied cyber-physical systems

    CERN Document Server

    Suh, Sang C; Carbone, John N

    2013-01-01

    From the reviews: "This book is an edited volume with contributions from the leading experts on the topic of CPS and presents diverse application examples and challenges in CPS. … Advanced-level undergraduate and graduate students and researchers in the fields of computer science and engineering will find this book very useful as a reference." (D. Subbaram Naidu, Amazon.com, January, 2014)

  14. Cyber Physical Systems Approach to Power Electronics Education

    Directory of Open Access Journals (Sweden)

    Marko Vekić

    2012-12-01

    Full Text Available This paper proposes a Cyber Physical Approach (CPS to power electronics (PE education where all aspects of PE technology from circuit topology to the implementation of real time control code on a microprocessor are dealt with as an inseparable whole, and only the system complexity is increased during the course of instruction. This approach is now made practical thanks to the affordable and unrestricted access to high-power PE laboratory infrastructure (PE laboratory in a box in the form of high-fidelity digital PE emulators with 1us calculation time step and latency.

  15. 1st International Conference on Machine Learning for Cyber Physical Systems and Industry 4.0

    CERN Document Server

    Beyerer, Jürgen

    2016-01-01

    The work presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains some selected papers from the international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Lemgo, October 1-2, 2015. Cyber Physical Systems are characterized by their ability to adapt and to learn: They analyze their environment and, based on observations, they learn patterns, correlations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnosis. Machine Learning is the key technology for these developments.

  16. Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare.

    Science.gov (United States)

    Zerbe, Philipp; Chiang, Angela; Dullat, Harpreet; O'Neil-Johnson, Mark; Starks, Courtney; Hamberger, Björn; Bohlmann, Jörg

    2014-09-01

    Marrubium vulgare (Lamiaceae) is a medicinal plant whose major bioactive compounds, marrubiin and other labdane-related furanoid diterpenoids, have potential applications as anti-diabetics, analgesics or vasorelaxants. Metabolite and transcriptome profiling of M. vulgare leaves identified five different candidate diterpene synthases (diTPSs) of the TPS-c and TPS-e/f clades. We describe the in vitro and in vivo functional characterization of the M. vulgare diTPS family. In addition to MvEKS ent-kaurene synthase of general metabolism, we identified three diTPSs of specialized metabolism: MvCPS3 (+)-copalyl diphosphate synthase, and the functional diTPS pair MvCPS1 and MvELS. In a sequential reaction, MvCPS1 and MvELS produce a unique oxygenated diterpene scaffold 9,13-epoxy-labd-14-ene en route to marrubiin and an array of related compounds. In contrast with previously known diTPSs that introduce a hydroxyl group at carbon C-8 of the labdane backbone, the MvCPS1-catalyzed reaction proceeds via oxygenation of an intermediate carbocation at C-9, yielding the bicyclic peregrinol diphosphate. MvELS belongs to a subgroup of the diTPS TPS-e/f clade with unusual βα-domain architecture. MvELS is active in vitro and in vivo with three different prenyl diphosphate substrates forming the marrubiin precursor 9,13-epoxy-labd-14-ene, as identified by nuclear magnetic resonance (NMR) analysis, manoyl oxide and miltiradiene. MvELS fills a central position in the biosynthetic system that forms the foundation for the diverse repertoire of Marrubium diterpenoids. Co-expression of MvCPS1 and MvELS in engineered E. coli and Nicotiana benthamiana offers opportunities for producing precursors for an array of biologically active diterpenoids. © 2014 The Authors The Plant Journal © 2014 John Wiley & Sons Ltd.

  17. Katilini Yaratan Annelik: Elif Şafak'ın "İskender" Adlı Romanından Yola Çıkarak Türkiye'de Kadınlık Ve Erkeklik Rollerine Dair Bir Sorgulama Motherhood Creating Its Killer: Based On Elif Shafak's Novel "Alexander" Questioning The Femininity And Masculinity In Turkey

    Directory of Open Access Journals (Sweden)

    İlknur MEŞE

    2013-03-01

    Full Text Available Elif Shafak‟s novel “Alexander” holds many references tofemininity and masculinity in the context of the „purity‟ of woman and„honor‟ of man, which still exist in Turkey. On the cover of the book, thewriter poses in man‟s suit which tells us that it is woman –especiallymothers- who prepares man to the appropriate masculinity. Theinequality between man and woman has been built culturally ratherthan a natural result created by biological differences. The concept ofmasculinity has been shaped by political, ideological, and marketorientedinterests. In this sense, masculinity gained hard meanings likemind, power, will, achievement, activity, committing violence, actingindependently, and knowing to rule the others. However, the concept offemininity - having the reverse situation- has soft meanings likecompassion, pity, conscience, peaceful, passivity, and sensuality.Woman has tried to negotiate her secondary position by aspiringthe power of man. In this sense, we can assess woman‟s wish for a malechild as a wish of legitimate power. Her wish of compensating herhelplessness with the power attributed to man has no benefit otherthan creating anothervictimhood. Femininity and its repercussionmotherhood are something produced down the generations. More orless each new generation has been affected by this legacy. Both menand women will be able to get over this power cycle by questioning thecultural system and using the capacity of their subjectivity. Elif Şafak‟ın “İskender” adlı romanı, Türkiye‟de halen varlığınısürdüren, kadının „namusu‟ ve erkeğin „şerefi‟ üzerinden kadınlık veerkeklik rolleri tanımlamalarına dair çok göndermeler bulabileceğimizbir eser. Yazarın, kitabın kapağında bir erkek takım elbisesi içindeverdiği pozun bize anlattığı şey, tıpkı romanın başkahramanı olanİskender gibi, erkekleri, kabullere uygun erkeklik rolüne hazırlayanlarınkadınlar -özellikle anneler

  18. Influence of ad libitum milk replacer feeding and butyrate supplementation on the systemic and hepatic insulin-like growth factor I and its binding proteins in Holstein calves.

    Science.gov (United States)

    Frieten, D; Gerbert, C; Koch, C; Dusel, G; Eder, K; Hoeflich, A; Mielenz, B; Hammon, H M

    2018-02-01

    Ad libitum milk feeding and butyrate (B) supplementation have the potential to stimulate postnatal growth and development in calves. The somatotropic axis is the main endocrine regulator of postnatal growth and may be affected by both ad libitum milk replacer (MR) feeding and B supplementation in calves. We hypothesized that ad libitum MR feeding and B supplementation stimulate systemic and hepatic insulin-like growth factor (IGF)-I and IGF binding proteins (IGFBP) in preweaning calves. Sixty-four (32 male, 32 female) Holstein calves were examined from birth until wk 11 of life. Calves received MR either ad libitum (Adl) or restrictively (6 L/d; Res). In each feeding group half of the calves received a MR with 0.24% butyrate and the other half received same MR without butyrate. Ad libitum MR feeding was performed from d 4 until wk 8 of age. From wk 9 to 10, Adl and Res calves were gradually weaned and were fed 2 L/d until the end of the trial. Concentrate, hay, and water were freely available. Feed intake was measured daily and body weight weekly. Blood samples for analyzing plasma concentrations of glucose, insulin, IGF-I, and IGFBP-2, -3, and -4 were taken on d 1, 2, 4, and 7, then weekly or every other week (IGFBP) until wk 11 of life. Liver samples were taken on d 50 and at the end of the study (d 80) to measure gene expression of the growth hormone receptor 1A (GHR1A), IGF1, IGFBP1 to 4, and of the IGF Type 1 and insulin receptor in the liver. Intake of MR and body weight were greater, but concentrate intake was lower in Adl than in Res. Plasma concentrations of IGF-I and IGFBP-3 were greater and plasma concentration of IGFBP-2 was lower in Adl than in Res during the ad libitum milk feeding period. After reduction of MR in both groups to 2 L/d plasma concentrations of IGF-I and IGFBP-4 were lower and plasma concentration of IGFBP-2 was higher in Adl than in Res. Supplementation of B depressed plasma IGF-I from wk 1 to 4 and in wk 9. On d 50, mRNA abundance of

  19. [Recording of ventricular pressure by conventional catheter manometer systems. Efficiency of several combinations of conventional catheters, modern transducers and catheter-flush systems (author's transl)].

    Science.gov (United States)

    Hellige, G

    1976-01-01

    The experimentally in vitro determined dynamic response characteristics of 38 catheter manometer systems were uniform in the worst case to 5 c.p.s. and optimally to 26 c.p.s. Accordingly, some systems are only satisfactory for ordinary pressure recording in cardiac rest, while better systems record dp/dt correct up to moderate inotropic stimulation of the heart. In the frequency range of uniform response (amplitude error less +/- 5%) the phase distortion is also negligible. In clinical application the investigator is often restricted to special type of cardiac catheter. In this case a low compliant transducer yields superior results. In all examined systems the combination with MSD 10 transducers is best, whereas the combination with P 23 Db transducers leads to minimal results. An inadequate system for recording ventricular pressure pulses leads in most cases to overestimations of dp/dtmax. The use of low frequency pass filters to attenuate higher frequency artefacts is, under clinical conditions, not suitable for extending the range of uniform frequency response. The dynamic response of 14 catheter manometer systems with two types of continuous self flush units was determined. The use of the P 37 flush unit in combination with small internal diameter catheters leads to serious error in ordinary pressure recording, due to amplitude distortion of the lower harmonics. The frequency response characteristics of the combination of an Intraflow flush system and MSD 10 transducer was similar to the non-flushing P 23 Db transducer feature.

  20. The Application of Cyber Physical System for Thermal Power Plants: Data-Driven Modeling

    Directory of Open Access Journals (Sweden)

    Yongping Yang

    2018-03-01

    Full Text Available Optimal operation of energy systems plays an important role to enhance their lifetime security and efficiency. The determination of optimal operating strategies requires intelligent utilization of massive data accumulated during operation or prediction. The investigation of these data solely without combining physical models may run the risk that the established relationships between inputs and outputs, the models which reproduce the behavior of the considered system/component in a wide range of boundary conditions, are invalid for certain boundary conditions, which never occur in the database employed. Therefore, combining big data with physical models via cyber physical systems (CPS is of great importance to derive highly-reliable and -accurate models and becomes more and more popular in practical applications. In this paper, we focus on the description of a systematic method to apply CPS to the performance analysis and decision making of thermal power plants. We proposed a general procedure of CPS with both offline and online phases for its application to thermal power plants and discussed the corresponding methods employed to support each sub-procedure. As an example, a data-driven model of turbine island of an existing air-cooling based thermal power plant is established with the proposed procedure and demonstrates its practicality, validity and flexibility. To establish such model, the historical operating data are employed in the cyber layer for modeling and linking each physical component. The decision-making procedure of optimal frequency of air-cooling condenser is also illustrated to show its applicability of online use. It is concluded that the cyber physical system with the data mining technique is effective and promising to facilitate the real-time analysis and control of thermal power plants.

  1. Performance analysis of multiple interference suppression over asynchronous/synchronous optical code-division multiple-access system based on complementary/prime/shifted coding scheme

    Science.gov (United States)

    Nieh, Ta-Chun; Yang, Chao-Chin; Huang, Jen-Fa

    2011-08-01

    A complete complementary/prime/shifted prime (CPS) code family for the optical code-division multiple-access (OCDMA) system is proposed. Based on the ability of complete complementary (CC) code, the multiple-access interference (MAI) can be suppressed and eliminated via spectral amplitude coding (SAC) OCDMA system under asynchronous/synchronous transmission. By utilizing the shifted prime (SP) code in the SAC scheme, the hardware implementation of encoder/decoder can be simplified with a reduced number of optical components, such as arrayed waveguide grating (AWG) and fiber Bragg grating (FBG). This system has a superior performance as compared to previous bipolar-bipolar coding OCDMA systems.

  2. An Unobtrusive Fall Detection and Alerting System Based on Kalman Filter and Bayes Network Classifier.

    Science.gov (United States)

    He, Jian; Bai, Shuang; Wang, Xiaoyi

    2017-06-16

    Falls are one of the main health risks among the elderly. A fall detection system based on inertial sensors can automatically detect fall event and alert a caregiver for immediate assistance, so as to reduce injuries causing by falls. Nevertheless, most inertial sensor-based fall detection technologies have focused on the accuracy of detection while neglecting quantization noise caused by inertial sensor. In this paper, an activity model based on tri-axial acceleration and gyroscope is proposed, and the difference between activities of daily living (ADLs) and falls is analyzed. Meanwhile, a Kalman filter is proposed to preprocess the raw data so as to reduce noise. A sliding window and Bayes network classifier are introduced to develop a wearable fall detection system, which is composed of a wearable motion sensor and a smart phone. The experiment shows that the proposed system distinguishes simulated falls from ADLs with a high accuracy of 95.67%, while sensitivity and specificity are 99.0% and 95.0%, respectively. Furthermore, the smart phone can issue an alarm to caregivers so as to provide timely and accurate help for the elderly, as soon as the system detects a fall.

  3. Formal methods for design and simulation of embedded systems

    DEFF Research Database (Denmark)

    Jakobsen, Mikkel Koefoed

    Cyper physical systems (CPSs) are present in many variants in our daily life. The complexity of developing a CPS is quickly increasing and the interaction between different CPSs is increasingly important. The interaction of the systems is becomming more and more fluent and seamless. This thesis...... presents the development of a formal systems modelling (ForSyDe) framework for modelling CPSs. The formalism of the framework makes computer aided design (CAD) a possibility for developing CPSs. The framework consists of four models of computation (MoCs): synchronous (SY), synchronous data flow (SDF...... different design challenges. With the ForSyDe framework, the use cases are expressed as homogeneous and heterogeneous models. The company use case illustrates that the ForSyDe framework handles systems with well defined interactions very well. The WSN use case illustrates that networked systems with complex...

  4. Smart manufacturing systems for Industry 4.0: Conceptual framework, scenarios, and future perspectives

    Science.gov (United States)

    Zheng, Pai; wang, Honghui; Sang, Zhiqian; Zhong, Ray Y.; Liu, Yongkui; Liu, Chao; Mubarok, Khamdi; Yu, Shiqiang; Xu, Xun

    2018-01-01

    Information and communication technology is undergoing rapid development, and many disruptive technologies, such as cloud computing, Internet of Things, big data, and artificial intelligence, have emerged. These technologies are permeating the manufacturing industry and enable the fusion of physical and virtual worlds through cyber-physical systems (CPS), which mark the advent of the fourth stage of industrial production (i.e., Industry 4.0). The widespread application of CPS in manufacturing environments renders manufacturing systems increasingly smart. To advance research on the implementation of Industry 4.0, this study examines smart manufacturing systems for Industry 4.0. First, a conceptual framework of smart manufacturing systems for Industry 4.0 is presented. Second, demonstrative scenarios that pertain to smart design, smart machining, smart control, smart monitoring, and smart scheduling, are presented. Key technologies and their possible applications to Industry 4.0 smart manufacturing systems are reviewed based on these demonstrative scenarios. Finally, challenges and future perspectives are identified and discussed.

  5. RELEVANT OBJECTIVES OF ASSURANCE OF RELIABILITY OF FACADE SYSTEMS SERVING THERMAL INSULATION AND FINISHING PURPOSES

    Directory of Open Access Journals (Sweden)

    Yavorskiy Andrey Andreevich

    2012-12-01

    Full Text Available The authors consider up-to-date methods of implementation of requirements stipulated by Federal Law no. 261-FZ that encompasses reduction of heat losses through installation of progressive heat-insulation systems, cement plaster system (CPS, and ventilated facades (VF. Unresolved problems of their efficient application caused by the absence of the all-Russian regulatory documents capable of controlling the processes of their installation and maintenance, as well as the projection of their behaviour, are also considered in the article. The authors argue that professional skills of designers and construction workers responsible for the design and installation of façade systems influence the quality and reliability of design and construction works. Unavailability of unified solutions or regulations serves as the objective reason for the unavailability of the respective database; therefore, there is an urgent need to perform a set of researches to have the unified database compiled. The authors use the example of thermal insulation cement plaster systems designated for facades as results of researches into the quantitative analysis of safety systems. Collected and systematized data that cover defects that have proven to be reasons for failures, as well as potential methods of their prevention are also studied. Data on pilot studies of major factors of influence onto reliability of glutinous adhesion of CPS to the base of a wall are provided.

  6. Prediction-based manufacturing center self-adaptive demand side energy optimization in cyber physical systems

    Science.gov (United States)

    Sun, Xinyao; Wang, Xue; Wu, Jiangwei; Liu, Youda

    2014-05-01

    Cyber physical systems(CPS) recently emerge as a new technology which can provide promising approaches to demand side management(DSM), an important capability in industrial power systems. Meanwhile, the manufacturing center is a typical industrial power subsystem with dozens of high energy consumption devices which have complex physical dynamics. DSM, integrated with CPS, is an effective methodology for solving energy optimization problems in manufacturing center. This paper presents a prediction-based manufacturing center self-adaptive energy optimization method for demand side management in cyber physical systems. To gain prior knowledge of DSM operating results, a sparse Bayesian learning based componential forecasting method is introduced to predict 24-hour electric load levels for specific industrial areas in China. From this data, a pricing strategy is designed based on short-term load forecasting results. To minimize total energy costs while guaranteeing manufacturing center service quality, an adaptive demand side energy optimization algorithm is presented. The proposed scheme is tested in a machining center energy optimization experiment. An AMI sensing system is then used to measure the demand side energy consumption of the manufacturing center. Based on the data collected from the sensing system, the load prediction-based energy optimization scheme is implemented. By employing both the PSO and the CPSO method, the problem of DSM in the manufacturing center is solved. The results of the experiment show the self-adaptive CPSO energy optimization method enhances optimization by 5% compared with the traditional PSO optimization method.

  7. TASK ALLOCATION IN GEO-DISTRIBUTATED CYBER-PHYSICAL SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Aggarwal, Rachel; Smidts, Carol

    2017-03-01

    This paper studies the task allocation algorithm for a distributed test facility (DTF), which aims to assemble geo-distributed cyber (software) and physical (hardware in the loop components into a prototype cyber-physical system (CPS). This allows low cost testing on an early conceptual prototype (ECP) of the ultimate CPS (UCPS) to be developed. The DTF provides an instrumentation interface for carrying out reliability experiments remotely such as fault propagation analysis and in-situ testing of hardware and software components in a simulated environment. Unfortunately, the geo-distribution introduces an overhead that is not inherent to the UCPS, i.e. a significant time delay in communication that threatens the stability of the ECP and is not an appropriate representation of the behavior of the UCPS. This can be mitigated by implementing a task allocation algorithm to find a suitable configuration and assign the software components to appropriate computational locations, dynamically. This would allow the ECP to operate more efficiently with less probability of being unstable due to the delays introduced by geo-distribution. The task allocation algorithm proposed in this work uses a Monte Carlo approach along with Dynamic Programming to identify the optimal network configuration to keep the time delays to a minimum.

  8. Cable pin system versus K-wire tension band fixation for patella fractures in Chinese Han population: A meta-analysis.

    Science.gov (United States)

    Zha, Kun; Liu, Guo-Hui; Yang, Shu-Hua; Zhou, Wu; Liu, Yi; Wu, Qi-Peng

    2017-10-01

    This meta-analysis compared the therapeutic effect of cable pin system (CPS) with K-wire tension band (KTB) in the treatment of patella fractures among Chinese Han population. The databases of PubMed, Cochrane library, China National Knowledge Infrastructure (CNKI), Chinese WanFang and Chinese VIP were searched for studies on CPS versus KTB in the treatment of patella fractures among Chinese Han population. Literatures were screened according to the inclusion and exclusion criteria. The quality of the studies was assessed, and meta-analysis was performed using the Cochrane Collaboration's REVMAN 5.3 software. A total of 932 patients from 15 studies were included in this meta-analysis (426 fractures treated with CPS and 506 fractures treated with KTB). There were significant differences in duration of hospital stay [mean difference (MD)=-1.07; 95% confidence interval (CI):-1.71 to-0.43], fracture healing time (MD=-1.23; 95% CI:-1.68 to-0.77), flexion degree of knee joint at 6th month after operation (MD=14.82; 95% CI: 10.93 to 18.71), incidence of postoperative complication [risk ratio (RR)=0.16; 95% CI: 0.09 to 0.27] and excellent-good rate of Böstman score (RR=1.09; 95% CI: 1.03 to 1.16) between the CPS group and KTB group, while no significant difference was found in operative time between the two groups (MD=-4.52; 95% CI:-11.70 to 2.67). For the treatment of patella fractures among Chinese Han population, limited evidence suggests that the CPS is more suitable than the KTB when considering the hospital stay, fracture healing time, flexion degree of knee at 6th month after operation, incidence of postoperative complication and excellent-good rate of Böstman joint score. Due to the limitation of high quality evidence and sample size, more large-scale randomized controlled trials are needed to validate the findings in the future.

  9. Molecular Structural Characteristics of Polysaccharide Fractions from Canarium album (Lour.) Raeusch and Their Antioxidant Activities.

    Science.gov (United States)

    Zeng, Hongliang; Miao, Song; Zheng, Baodong; Lin, Shan; Jian, Yeye; Chen, Shen; Zhang, Yi

    2015-11-01

    The objective of this study was to investigate the multiple relations between the preliminary molecular structural characteristics and antioxidant activities of polysaccharides from Canarium album (Lour.) Raeusch (CPS). Three polysaccharide fractions, CPS1, CPS2, and CPS3, were isolated from CPS by column chromatography. CPS1 and CPS3 were mainly composed of neutral polysaccharides linked by α- and β-glycosidic linkages while CPS2 was pectin polysaccharides mainly linked by β-glycosidic linkages. According to the SEC-MALLS-RI system, the molecular weight of CPS1 was greater compared to CPS2 and CPS3, and the molecular weight and radius of CPS did not display positive correlation. The chain conformation analysis indicated CPS1 and CPS2 were typical highly branched polysaccharides while CPS3 existed as a globular shape in aqueous. Furthermore, the antioxidant activity of CPS2 was better than that of CPS3, while that of CPS1 was the weakest. The antioxidant activities of polysaccharide fractions were affected by their monosaccharide composition, glycosidic linkage, molecular weight, and chain conformation. This functional property was a result of a combination of multiple molecular structural factors. CPS2 was the major antioxidant component of CPS and it could be exploited as a valued antioxidant product. The molecular structural characteristics, antioxidant activities, and structure-function relationships of polysaccharide fractions from Canarium album were first investigated in this study. The results provided background and practical knowledge for the deep-processed products of C. album with high added value. CPS2 was the major antioxidant component of CPS, which could be exploited as a valued antioxidant ingredient in food and pharmaceutical industries. © 2015 Institute of Food Technologists®

  10. Period selection for integrated controller tasks in cyber-physical systems

    Directory of Open Access Journals (Sweden)

    Du Chenglie

    2015-06-01

    Full Text Available Performance optimization of cyber-physical systems (CPS calls for co-design strategies that handle the issues in both computing domain and physical domain. Periods of controller tasks integrated into a uniprocessor system are related to both control performance and real-time schedulability analysis simultaneously. System performance improvement can be achieved by optimizing the periods of controller tasks. This paper extends an existing model to select task periods in real-time for CPS with fixed priority controller tasks scheduled by rate-monotonic algorithm. When all the tasks can be integrated, the analytic solution of the problem is derived by using the method of Lagrange multipliers and gradient descent method is evaluated to be suitable online. To further deal with the condition that the system is overloaded, an integrated method is proposed to select periods of tasks online by selecting a subset of tasks first and then optimizing the periods for them. Experimental results demonstrate that our method yields near-optimal result with a short running time.

  11. Systems

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    Papers in this session describe the concept of mined geologic disposal system and methods for ensuring that the system, when developed, will meet all technical requirements. Also presented in the session are analyses of system parameters, such as cost and nuclear criticality potential, as well as a technical analysis of a requirement that the system permit retrieval of the waste for some period of time. The final paper discusses studies under way to investigate technical alternatives or complements to the mined geologic disposal system. Titles of the presented papers are: (1) Waste Isolation System; (2) Waste Isolation Economics; (3) BWIP Technical Baseline; (4) Criticality Considerations in Geologic Disposal of High-Level Waste; (5) Retrieving Nuclear Wastes from Repository; (6) NWTS Programs for the Evaluation of Technical Alternatives or Complements to Mined Geologic Repositories - Purpose and Objectives

  12. systems

    Directory of Open Access Journals (Sweden)

    Alexander Leonessa

    2000-01-01

    Full Text Available A nonlinear robust control-system design framework predicated on a hierarchical switching controller architecture parameterized over a set of moving nominal system equilibria is developed. Specifically, using equilibria-dependent Lyapunov functions, a hierarchical nonlinear robust control strategy is developed that robustly stabilizes a given nonlinear system over a prescribed range of system uncertainty by robustly stabilizing a collection of nonlinear controlled uncertain subsystems. The robust switching nonlinear controller architecture is designed based on a generalized (lower semicontinuous Lyapunov function obtained by minimizing a potential function over a given switching set induced by the parameterized nominal system equilibria. The proposed framework robustly stabilizes a compact positively invariant set of a given nonlinear uncertain dynamical system with structured parametric uncertainty. Finally, the efficacy of the proposed approach is demonstrated on a jet engine propulsion control problem with uncertain pressure-flow map data.

  13. Conceptual design of tritium accountancy system for LLCB TBM

    International Nuclear Information System (INIS)

    Patel, Rudreksh; Sircar, Amit

    2017-01-01

    Lead Lithium Ceramic Breeder (LLCB) Test Blanket Module (TBM) will be tested in ITER for performance evaluation of high grade of heat extraction and tritium breeding. The bred tritium in the breeder materials is extracted and recovered by Tritium Extraction System (TES), whereas tritium permeated from breeder materials to helium coolants, viz., primary coolant and secondary coolant, is recovered by Coolant Purification System (CPS). This recovered tritium has to be accounted before transferring it to tritium plant (i.e., ITER inner fuel). This tritium accountancy is performed by Tritium Accountancy System (TAS). In addition to tritium accountancy, TAS also provides necessary data for the validation of design and modelling tools.In this work, we have presented conceptual design of TAS. It also describes operational philosophy, process parameters, process flow diagram, and interface details with ITER tritium plant. (author)

  14. Model-Based Development and Evaluation of Control for Complex Multi-Domain Systems

    DEFF Research Database (Denmark)

    Grujic, Ivan; Nilsson, Rene

    of such systems, caused by technological advances in all domains, new ways of approaching multi- domain system development are needed. One methodology, which excels in complexity management, is model-based development. Multidomain systems require collaborative modeling, where the physical system dynamics...... Unmanned Aerial Vehicle (UAV) has been constructed and used to develop an attitude controller based on Model Predictive Control (MPC). The MPC controller has been compared to an existing open source Proportional Integral Derivative (PID) attitude controller. This thesis contributes to the discipline......A Cyber-Physical System (CPS) incorporates sensing, actuating, computing and communicative capabilities, which are often combined to control the system. The development of CPSs poses a challenge, since the complexity of the physical system dynamics must be taken into account when designing...

  15. AMEM-ADL Polymer Migration Estimation Model User's Guide

    Science.gov (United States)

    The user's guide of the Arthur D. Little Polymer Migration Estimation Model (AMEM) provides the information on how the model estimates the fraction of a chemical additive that diffuses through polymeric matrices.

  16. Client-centred ADL intervention after stroke: Occupational therapists' experiences.

    Science.gov (United States)

    Ranner, Maria; von Koch, Lena; Guidetti, Susanne; Tham, Kerstin

    2016-01-01

    This study was conducted in the context of a randomized controlled trial evaluating the effect of a client-centred activities in daily living intervention (CADL). The aim of the CADL was to enable agency in daily activities and participation in everyday life among persons with stroke. This qualitative, longitudinal study aimed to describe how occupational therapists (OTs) applied the CADL in their clinical practice by studying their experiences and reflections concerning their interaction with the clients with stroke. Six OTs who conducted the CADL were followed through interviews and observations on four separate occasions over one year. Data were analysed using a grounded theory approach. Sharing was the core category showing how the OTs helped their clients to achieve agency in daily activities. Through sharing the situation the OTs strove to obtain an empathetic understanding of the clients' lived experience throughout the whole intervention process in order to enable the clients' ownership of their daily activities. The continuity of sharing seems to be the key for a gradual increase in agency. The approach of sharing should preferably be applied by all members of the interprofessional team, including the client and significant others.

  17. Substantiating Recommendations on the Choice of an Efficient Strategy of the State Regulation for System of Monitoring Economy Branches

    Directory of Open Access Journals (Sweden)

    Ashchaulov Vitalii V.

    2016-01-01

    Full Text Available The article is concerned with substantiating recommendations on the choice of an effective strategy of the State regulation for system of monitoring economy branches. To display the financial aspect of the enterprise's strategic positioning in the sectoral environment, a modified ADL matrix was used. A matrix of choosing an optimum variant (scenario of the enterprise's financial strategy has been considered taking into account possibilities of its use in the system of monitoring the development of economic sectors. Disadvantages in the use of modified ADL matrices and in choosing an optimum variant (scenario financial strategy of the enterprise's financial strategy have been identified. Factors of internal and external environment, which affect the strategic choice of enterprises, have been determined and analyzed. The SPACE matrix for building the model of choosing a strategy of financing the development of enterprises in the economy branches has been modified in the context of the system of monitoring the development of economy branches. A description of the strategies proposed by author for financing the development of enterprise has been provided, their advantages and disadvantages have been determined. Individual tools of the proposed models of actions can be accepted as a way of improving the strategic positions with a view to achieving a higher quantitative-qualitative situation as well as adjustment of the existing model of behavior.

  18. An Occupancy Based Cyber-Physical System Design for Intelligent Building Automation

    Directory of Open Access Journals (Sweden)

    Kottarathil Eashy Mary Reena

    2015-01-01

    Full Text Available Cyber-physical system (CPS includes the class of Intelligent Building Automation System (IBAS which increasingly utilizes advanced technologies for long term stability, economy, longevity, and user comfort. However, there are diverse issues associated with wireless interconnection of the sensors, controllers, and power consuming physical end devices. In this paper, a novel architecture of CPS for wireless networked IBAS with priority-based access mechanism is proposed for zones in a large building with dynamically varying occupancy. Priority status of zones based on occupancy is determined using fuzzy inference engine. Nondominated Sorting Genetic Algorithm-II (NSGA-II is used to solve the optimization problem involving conflicting demands of minimizing total energy consumption and maximizing occupant comfort levels in building. An algorithm is proposed for power scheduling in sensor nodes to reduce their energy consumption. Wi-Fi with Elimination-Yield Nonpreemptive Multiple Access (EY-NPMA scheme is used for assigning priority among nodes for wireless channel access. Controller design techniques are also proposed for ensuring the stability of the closed loop control of IBAS in the presence of packet dropouts due to unreliable network links.

  19. A polysaccharide-degrading marine bacterium Flammeovirga sp. MY04 and its extracellular agarase system

    Science.gov (United States)

    Han, Wenjun; Gu, Jingyan; Yan, Qiujie; Li, Jungang; Wu, Zhihong; Gu, Qianqun; Li, Yuezhong

    2012-09-01

    Bacteria of the genus Flammeovirga can digest complex polysaccharides (CPs), but no details have been reported regarding the CP depolymerases of these bacteria. MY04, an agarolytic marine bacterium isolated from coastal sediments, has been identified as a new member of the genus Flammeovirga. The MY04 strain is able to utilize multiple CPs as a sole carbon source and grows well on agarose, mannan, or xylan. This strain produces high concentrations of extracellular proteins (490 mg L-1 ± 18.2 mg L-1 liquid culture) that exhibit efficient and extensive degradation activities on various polysaccharides, especially agarose. These proteins have an activity of 310 U mg-1 ± 9.6 U mg-1 proteins. The extracellular agarase system (EAS) in the crude extracellular enzymes contains at least four agarose depolymerases, which are with molecular masses of approximately 30-70 kDa. The EAS is stable at a wide range of pH values (6.0-11.0), temperatures (0-50°C), and sodium chloride (NaCl) concentrations (0-0.9 mol L-1). Two major degradation products generated from agarose by the EAS are identified to be neoagarotetraose and neoagarohexaose, suggesting that β-agarases are the major constituents of the MY04 EAS. These results suggest that the Flammeovirga strain MY04 and its polysaccharide-degradation system hold great promise in industrial applications.

  20. Development of core technology for KNGR system design; detailed analysis and related issue evaluation for MMI testing data

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dhong Ha [Suwon University, Whasung (Korea)

    2002-03-01

    This study evaluated man-machine interface (MMI) features of the advanced control room of Korea Next Generation Reactor. Major issues to be evaluated included: (1) supportability of large display panel (LDP) during passive monitoring (2) supportability of work station display (WSD) for interpretation and planning (3) supportability of combination of alarm, WSD, LDP and computerized procedure system (CPS) for interpretation and planning during single and multiple fault event, (4) supportability of softcontrol (SC) during simple operator-paced control task, (5) supportability of softcontrol (SC) during conditional operator-paced control task, and (6) supportability of alarm system for emergent operation procedure. Four operator teams of RO, TO, and SRO participated the test scenarios consisting of AOP and EOP. Performance data measuring situation awareness, workload, operation errors, and team work and operators' opinions for MMI features of advanced control room were collected during the experiment. Operators showed positive responses for issues (1) supportability of LDP during passive monitoring (2) supportability of WSD for interpretation and planning (3) supportability of combination of alarm, WSD, LDP and CPS for interpretation and planning during single and multiple fault event, (4) supportability of alarm system for normal operation procedure, while they suggested some needs to improve for issues: (1) supportability of softcontrol (SC) during simple and conditional operator-paced control task, (2) supportability of alarm system for emergent situation. 7 refs., 36 figs., 83 tabs. (Author)

  1. Multi-Objective Optimal Design of a Building Envelope and Structural System Using Cyber-Physical Modeling in a Wind Tunnel

    Directory of Open Access Journals (Sweden)

    Michael L. Whiteman

    2018-03-01

    Full Text Available This paper explores the use of a cyber-physical systems (CPS “loop-in-the-model” approach to optimally design the envelope and structural system of low-rise buildings subject to wind loads. Both the components and cladding (C&C and the main wind force resisting system (MWFRS are considered through multi-objective optimization. The CPS approach combines the physical accuracy of wind tunnel testing and efficiency of numerical optimization algorithms to obtain an optimal design. The approach is autonomous: experiments are executed in a boundary layer wind tunnel (BLWT, sensor feedback is monitored and analyzed by a computer, and optimization algorithms dictate physical changes to the structural model in the BLWT through actuators. To explore a CPS approach to multi-objective optimization, a low-rise building with a parapet wall of variable height is considered. In the BLWT, servo-motors are used to adjust the parapet to a particular height. Parapet walls alter the location of the roof corner vortices, reducing suction loads on the windward facing roof corners and edges, a C&C design load. At the same time, parapet walls increase the surface area of the building, leading to an increase in demand on the MWFRS. A combination of non-stochastic and stochastic optimization algorithms were implemented to minimize the magnitude of suction and positive pressures on the roof of a low-rise building model, followed by stochastic multi-objective optimization to simultaneously minimize the magnitude of suction pressures and base shear. Experiments were conducted at the University of Florida Experimental Facility (UFEF of the National Science Foundation’s (NSF Natural Hazard Engineering Research Infrastructure (NHERI program.

  2. Resource-Parameterized Timing Analysis of Real-Time Systems

    DEFF Research Database (Denmark)

    Kim, Jin Hyun; Legay, Axel; Larsen, Kim Guldstrand

    2015-01-01

    on a specic platform. For the same reason, a configuration of platforms cannot be independent from applications in most cases. This paper proposes a new analysis framework of real-time systems where an application and a platform can be analyzed in a fully independent way such that not only the application......Cyber-Physical Systems (CPS) are subject to platform-given resource constraints upon such resources as CPU, memory, and bus, in executing their functionalities. This causes the behavior of a verified application to deviate from its intended timing behavior when the application is integrated...... but also the platform once verfiied can be exploited by various applications. The dependent behaviors of application and platform are also analyzed by exploiting their individual models transformed from their independent models. To the end, we provide a highly configurable platform model that can...

  3. Advances in Intelligent Control Systems and Computer Science

    CERN Document Server

    2013-01-01

    The conception of real-time control networks taking into account, as an integrating approach, both the specific aspects of information and knowledge processing and the dynamic and energetic particularities of physical processes and of communication networks is representing one of the newest scientific and technological challenges. The new paradigm of Cyber-Physical Systems (CPS) reflects this tendency and will certainly change the evolution of the technology, with major social and economic impact. This book presents significant results in the field of process control and advanced information and knowledge processing, with applications in the fields of robotics, biotechnology, environment, energy, transportation, et al.. It introduces intelligent control concepts and strategies as well as real-time implementation aspects for complex control approaches. One of the sections is dedicated to the complex problem of designing software systems for distributed information processing networks. Problems as complexity an...

  4. Necip Fazıl Kısakürek’in Yunus Emre Adlı Tiyatro Eseri Üzerine Bir İnceleme A Study About Yunus Emre, A Theatre Work Written By Necip Fazıl Kısakürek

    Directory of Open Access Journals (Sweden)

    Turan GÜLER

    2012-09-01

    ürler içinde tiyatroya büyük bir önem veren Necip Fazıl Kısakürek, Yunus Emre adlı oyununda Yunus Emre‟ye oyunun başkişisi olarak yer vermiştir. Bu çalışmada Necip Fazıl Kısakürek‟in Yunus Emre adlı tiyatrosu, oyunun kimlik çözümlemesi, konusu, olay dizisi, kişilik çözümlemesi, mekân ve dekor çözümlemeleri gibi yapısal unsurları bakımından incelenecektir. Eserde Türk-İslam tarihi içinde önemli bir yere sahip olan Yunus Emre‟nin menkıbelere dayalı hayatı tablolaştırılmıştır. Bu tablo içinde bir yandan Yunus Emre‟nin Anadolu‟ya gelmesi ile başlayan serüveni anlatılırken diğer yandan şiirleri aracılığı ile Yunus Emre‟nin yaşadığı tasavvufi yolculuk anlatılır. Oyunda, Yunus Emre devrinde Anadolu‟da vuku bulan bazı sosyal ve siyasal olaylara da göndermeler yapılır. Anadolu‟daki Moğol saldırıları ve hakimiyeti, Selçuklu Devleti‟nin son durumu, Beylikler arasındaki iç çekişmeler, halkın çaresizliği, bu karmaşa içinde tarikatların üstlendikleri çeşitli roller gibi meselelere oyunda yer verilmiştir. İncelememizde yapısal unsurların yanı sıra, bu gibi tematik hususlara da temas edilmiştir. Bu şekilde Yunus Emre‟nin çok fonksiyonlu kimliği ortaya konmaya çalışılmıştır. Son olarak yazar için önemli bir husus olan „Büyük Cihad‟ yani nefis terbiyesi gibi oyunun asıl tez konusuna dikkat çekilmiştir.

  5. systems

    Directory of Open Access Journals (Sweden)

    Patrick L. Brockett

    1978-01-01

    Full Text Available Suppose S={{Xnj,   j=1,2,…,kn}} is an infinitesimal system of random variables whose centered sums converge in law to a (necessarily infinitely divisible distribution with Levy representation determined by the triple (γ,σ2,M. If {Yj,   j=1,2,…} are independent indentically distributed random variables independent of S, then the system S′={{YjXnj,j=1,2,…,kn}} is obtained by randomizing the scale parameters in S according to the distribution of Y1. We give sufficient conditions on the distribution of Y in terms of an index of convergence of S, to insure that centered sums from S′ be convergent. If such sums converge to a distribution determined by (γ′,(σ′2,Λ, then the exact relationship between (γ,σ2,M and (γ′,(σ′2,Λ is established. Also investigated is when limit distributions from S and S′ are of the same type, and conditions insuring products of random variables belong to the domain of attraction of a stable law.

  6. Towards an Automated Requirements-driven Development of Smart Cyber-Physical Systems

    Directory of Open Access Journals (Sweden)

    Jiri Vinarek

    2016-03-01

    Full Text Available The Invariant Refinement Method for Self Adaptation (IRM-SA is a design method targeting development of smart Cyber-Physical Systems (sCPS. It allows for a systematic translation of the system requirements into the system architecture expressed as an ensemble-based component system (EBCS. However, since the requirements are captured using natural language, there exists the danger of their misinterpretation due to natural language requirements' ambiguity, which could eventually lead to design errors. Thus, automation and validation of the design process is desirable. In this paper, we (i analyze the translation process of natural language requirements into the IRM-SA model, (ii identify individual steps that can be automated and/or validated using natural language processing techniques, and (iii propose suitable methods.

  7. Analyzing SystemC Designs: SystemC Analysis Approaches for Varying Applications

    Directory of Open Access Journals (Sweden)

    Jannis Stoppe

    2015-05-01

    Full Text Available The complexity of hardware designs is still increasing according to Moore’s law. With embedded systems being more and more intertwined and working together not only with each other, but also with their environments as cyber physical systems (CPSs, more streamlined development workflows are employed to handle the increasing complexity during a system’s design phase. SystemC is a C++ library for the design of hardware/software systems, enabling the designer to quickly prototype, e.g., a distributed CPS without having to decide about particular implementation details (such as whether to implement a feature in hardware or in software early in the design process. Thereby, this approach reduces the initial implementation’s complexity by offering an abstract layer with which to build a working prototype. However, as SystemC is based on C++, analyzing designs becomes a difficult task due to the complex language features that are available to the designer. Several fundamentally different approaches for analyzing SystemC designs have been suggested. This work illustrates several different SystemC analysis approaches, including their specific advantages and shortcomings, allowing designers to pick the right tools to assist them with a specific problem during the design of a system using SystemC.

  8. SYSTEM

    Directory of Open Access Journals (Sweden)

    K. Swarnalatha

    2013-01-01

    Full Text Available Risk analysis of urban aquatic systems due to heavy metals turns significant due to their peculiar properties viz. persis tence, non-degradab ility, toxicity, and accumulation. Akkulam Veli (AV, an urba n tropical lake in south India is subjected to various environmental stresses due to multiple waste discharge, sand mining, developmental activities, tour ism related activitie s etc. Hence, a comprehensive approach is adopted for risk assessment using modified degree of contamination factor, toxicity units based on numerical sediment quality guidelines (SQGs, and potentialecological risk indices. The study revealed the presence of toxic metals such as Cr, C d, Pb and As and the lake is rated under ‘low ecological risk’ category.

  9. “Gülün Adı ve Benim Adım Kırmızı” Adlı Romanlara Karşılaştırmalı Bir Yaklaşım A Comparative Approach to the novels “Name of the Rose and My Name Is Red”

    Directory of Open Access Journals (Sweden)

    Elmas ŞAHİN

    2013-09-01

    Literature; Concepts of Criticism (1963, C:L: Wrenn'in The Idea of Comparative Literature (1973, Rey Chow'un In the Name of Comparative Literature (1995 gibi eserlerle, bizde ise İnci Enginün'ün Mukayeseli Edebiyat (1992, Gürsel Aytaç'ın Karşılaştırmalı Edebiyat Bilimi (1997, Emel Kefeli'nin Karşılaştırmalı Edebiyat İncelemeleri (2000 ve Kamil Aydın’ın Karşılaştırmalı Edebiyat: Günümüz Postmodern Bağlamda Algılanışı (2008 adlı çalışmalar karşılaştırmalı edebiyat bilimine katkı sağlayan ilk kuramsal yaklaşımlardandır.Karşılaştırmalı edebiyat, 1950’lerden sonra postmodern edebiyatın da gelişmesiyle birlikte metinlerarasılık kavramıyla da adını sıkça duyurmaya başlar. Gerek dil gerekse tema ve teknik açılardan eş ya da art zamanlı benzerlikler; metinlerarası göndermeler, alıntılar, montajlar; benzer söylemler ve kaynak metnin yeniden yorumlanışı gibi etkileşimler karşılaştırmalı edebiyat bilimini yakından ilgilendirir.Bu bağlamda çağımız yazarlarından İtalyan yazarı Umberto Eco'nun Gülün Adı (1980 ile Orhan Pamuk'un Benim Adım Kırmızı (1998 adlı eserleri farklı coğrafyalarda edebiyat sahasına girmelerine karşın, içerik ve biçim bağlamında benzer noktalara sahiptirler vekarşılaştırmalı edebiyat için eş zamanlı bir örnek teşkil etmektedirler.Bu çalışmada Gülün Adı ile Benim Adım Kırmızı adlı eserler, metneodaklı inceleme metodu kullanılarak öz ve biçim açısındankarşılaştırılacaktır. Her iki eser de, ortak tür, konu ve motifler dikkatealınarak; metinlerarası boyutta irdelenip; karşılaştırmalı edebiyatyönetimiyle benzer ve farklılıklarıyla çözümlenecektir.

  10. Measuring change in activities of daily living in nursing home residents with moderate to severe cognitive impairment

    Directory of Open Access Journals (Sweden)

    Fries Brant E

    2006-04-01

    Full Text Available Abstract Background The objective of this study was to assess the responsiveness of the Minimum Data Set Activities of Daily Living (MDS-ADL Scale to change over time by examining the change in physical function in adults with moderate to severe dementia with no comorbid illness who had been resident in a nursing home for over 90 days. Methods Longitudinal data were collected on nursing home residents with moderate (n = 7001 or severe (n = 4616 dementia in one US state from the US national Minimum Data Set (MDS. Severity of dementia was determined by the MDS Cognitive Performance Scale (CPS. Physical function was assessed by summing the seven items (bed mobility, transfer, locomotion, dressing, eating, toilet use, personal hygiene on the MDS activities of daily living (ADL Long Form scale. Mean change over time of MDS-ADL scores were estimated at three and six months for residents with moderate (CPS score of 3 and severe (CPS score of 4 or 5 dementia. Results Physical function in residents with moderate cognitive impairment deteriorated over six months by an average of 1.78 points on the MDS-ADL Long Form scale, while those with severe cognitive impairment declined by an average of 1.70 points. Approximately one quarter of residents in both groups showed some improvement in physical function over the six month period. Residents with moderate cognitive impairment experienced the greatest deterioration in early-loss and mid-loss ADL items (personal hygiene, dressing, toilet use and residents with severe cognitive impairment showed the greatest deterioration in activities related to eating, a late loss ADL. Conclusion The MDS-ADL Long Form scale detected clinically meaningful change in physical function in a large cohort of long-stay nursing home residents with moderate to severe dementia, supporting its use as a research tool in future studies.

  11. Measuring change in activities of daily living in nursing home residents with moderate to severe cognitive impairment

    Science.gov (United States)

    Carpenter, G Iain; Hastie, Charlotte L; Morris, John N; Fries, Brant E; Ankri, Joel

    2006-01-01

    Background The objective of this study was to assess the responsiveness of the Minimum Data Set Activities of Daily Living (MDS-ADL) Scale to change over time by examining the change in physical function in adults with moderate to severe dementia with no comorbid illness who had been resident in a nursing home for over 90 days. Methods Longitudinal data were collected on nursing home residents with moderate (n = 7001) or severe (n = 4616) dementia in one US state from the US national Minimum Data Set (MDS). Severity of dementia was determined by the MDS Cognitive Performance Scale (CPS). Physical function was assessed by summing the seven items (bed mobility, transfer, locomotion, dressing, eating, toilet use, personal hygiene) on the MDS activities of daily living (ADL) Long Form scale. Mean change over time of MDS-ADL scores were estimated at three and six months for residents with moderate (CPS score of 3) and severe (CPS score of 4 or 5) dementia. Results Physical function in residents with moderate cognitive impairment deteriorated over six months by an average of 1.78 points on the MDS-ADL Long Form scale, while those with severe cognitive impairment declined by an average of 1.70 points. Approximately one quarter of residents in both groups showed some improvement in physical function over the six month period. Residents with moderate cognitive impairment experienced the greatest deterioration in early-loss and mid-loss ADL items (personal hygiene, dressing, toilet use) and residents with severe cognitive impairment showed the greatest deterioration in activities related to eating, a late loss ADL. Conclusion The MDS-ADL Long Form scale detected clinically meaningful change in physical function in a large cohort of long-stay nursing home residents with moderate to severe dementia, supporting its use as a research tool in future studies. PMID:16584565

  12. Service differentiated and adaptive CSMA/CA over IEEE 802.15.4 for Cyber-Physical Systems.

    Science.gov (United States)

    Xia, Feng; Li, Jie; Hao, Ruonan; Kong, Xiangjie; Gao, Ruixia

    2013-01-01

    Cyber-Physical Systems (CPS) that collect, exchange, manage information, and coordinate actions are an integral part of the Smart Grid. In addition, Quality of Service (QoS) provisioning in CPS, especially in the wireless sensor/actuator networks, plays an essential role in Smart Grid applications. IEEE 802.15.4, which is one of the most widely used communication protocols in this area, still needs to be improved to meet multiple QoS requirements. This is because IEEE 802.15.4 slotted Carrier Sense Multiple Access/Collision Avoidance (CSMA/CA) employs static parameter configuration without supporting differentiated services and network self-adaptivity. To address this issue, this paper proposes a priority-based Service Differentiated and Adaptive CSMA/CA (SDA-CSMA/CA) algorithm to provide differentiated QoS for various Smart Grid applications as well as dynamically initialize backoff exponent according to traffic conditions. Simulation results demonstrate that the proposed SDA-CSMA/CA scheme significantly outperforms the IEEE 802.15.4 slotted CSMA/CA in terms of effective data rate, packet loss rate, and average delay.

  13. Cyber attack analysis on cyber-physical systems: Detectability, severity, and attenuation strategy

    Science.gov (United States)

    Kwon, Cheolhyeon

    Security of Cyber-Physical Systems (CPS) against malicious cyber attacks is an important yet challenging problem. Since most cyber attacks happen in erratic ways, it is usually intractable to describe and diagnose them systematically. Motivated by such difficulties, this thesis presents a set of theories and algorithms for a cyber-secure architecture of the CPS within the control theoretic perspective. Here, instead of identifying a specific cyber attack model, we are focused on analyzing the system's response during cyber attacks. Firstly, we investigate the detectability of the cyber attacks from the system's behavior under cyber attacks. Specifically, we conduct a study on the vulnerabilities in the CPS's monitoring system against the stealthy cyber attack that is carefully designed to avoid being detected by its detection scheme. After classifying three kinds of cyber attacks according to the attacker's ability to compromise the system, we derive the necessary and sufficient conditions under which such stealthy cyber attacks can be designed to cause the unbounded estimation error while not being detected. Then, the analytical design method of the optimal stealthy cyber attack that maximizes the estimation error is developed. The proposed stealthy cyber attack analysis is demonstrated with illustrative examples on Air Traffic Control (ATC) system and Unmanned Aerial Vehicle (UAV) navigation system applications. Secondly, in an attempt to study the CPSs' vulnerabilities in more detail, we further discuss a methodology to identify potential cyber threats inherent in the given CPSs and quantify the attack severity accordingly. We then develop an analytical algorithm to test the behavior of the CPS under various cyber attack combinations. Compared to a numerical approach, the analytical algorithm enables the prediction of the most effective cyber attack combinations without computing the severity of all possible attack combinations, thereby greatly reducing the

  14. Clinical analysis of the treatment of spinocerebellar ataxia and multiple system atrophy-cerebellar type with umbilical cord mesenchymal stromal cells.

    Science.gov (United States)

    Dongmei, Han; Jing, Liu; Mei, Xue; Ling, Zhu; Hongmin, Yan; Zhidong, Wang; Li, Ding; Zikuan, Guo; Hengxiang, Wang

    2011-09-01

    The aims of this study were to observe the safety and effectiveness of umbilical cord mesenchymal stromal cells (UC-MSC) in the treatment of spinocerebellar ataxia (SCA) and multiple system atrophy-cerebellar type (MSA-C). From October 2009 to September 2010, 14 cases of SCA and 10 cases of MSA-C were given UC-MSC by weekly intrathecal injection, at a dose of 1 × 10(6)/kg four times as one course. All the patients received one course of treatment, except three patients who received two courses. The movement ability and quality of daily life were evaluated with the International Cooperative Ataxia Rating Scale (ICARS) and Activity of Daily Living Scale (ADL) and the scores compared with those before cell therapy. A follow-up of 6-15 months was carried out for all of the patients. The results showed that the ICARS and ADL scores were significantly decreased 1 month after treatment (P pain (two cases) and headache (one case), which disappeared within 1-3 days. During the follow-up, 10 cases remained stable for half a year or longer, while 14 cases had regressed to the status prior to the treatment within 1-14 months (an average of 3 months). Intrathecal injection of UC-MSC is safe and can delay the progression of neurologic deficits for SCA and MSA-C patients.

  15. Physical Watermarking for Securing Cyber-Physical Systems via Packet Drop Injections

    Energy Technology Data Exchange (ETDEWEB)

    Ozel, Omur [Carnegie Mellon Univ., Pittsburgh, PA (United States); Weekrakkody, Sean [Carnegie Mellon Univ., Pittsburgh, PA (United States); Sinopoli, Bruno [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    2017-10-23

    Physical watermarking is a well known solution for detecting integrity attacks on Cyber-Physical Systems (CPSs) such as the smart grid. Here, a random control input is injected into the system in order to authenticate physical dynamics and sensors which may have been corrupted by adversaries. Packet drops may naturally occur in a CPS due to network imperfections. To our knowledge, previous work has not considered the role of packet drops in detecting integrity attacks. In this paper, we investigate the merit of injecting Bernoulli packet drops into the control inputs sent to actuators as a new physical watermarking scheme. With the classical linear quadratic objective function and an independent and identically distributed packet drop injection sequence, we study the effect of packet drops on meeting security and control objectives. Our results indicate that the packet drops could act as a potential physical watermark for attack detection in CPSs.

  16. A Formal Approach to Verify Parameterized Protocols in Mobile Cyber-Physical Systems

    Directory of Open Access Journals (Sweden)

    Long Zhang

    2017-01-01

    Full Text Available Mobile cyber-physical systems (CPSs are very hard to verify, because of asynchronous communication and the arbitrary number of components. Verification via model checking typically becomes impracticable due to the state space explosion caused by the system parameters and concurrency. In this paper, we propose a formal approach to verify the safety properties of parameterized protocols in mobile CPS. By using counter abstraction, the protocol is modeled as a Petri net. Then, a novel algorithm, which uses IC3 (the state-of-the-art model checking algorithm as the back-end engine, is presented to verify the Petri net model. The experimental results show that our new approach can greatly scale the verification capabilities compared favorably against several recently published approaches. In addition to solving the instances fast, our method is significant for its lower memory consumption.

  17. Upgrade of the Fast Beam Intensity Measurement System for the CERN PS Complex

    CERN Document Server

    Allica, JC; Andreazza, W; Belohrad, D; Favre, G; Favre, N; Jensen, L; Lenardon, F; Vollenberg, W

    2014-01-01

    The CERN Proton Synchrotron complex (CPS) has been operational for over 50 years. During this time the Fast Beam Current Transformers (FBCTs) have only been repaired when they ceased to function, or individually modified to cope with new requests. This strategy resulted in a large variation of designs, making their maintenance difficult and limiting the precision with which comparisons could be made between transformers for the measurement of beam intensity transmission. During the first long shutdown of the CERN LHC and its injectors (LS1) these systems have undergone a major consolidation, with detectors and acquisition electronics upgraded to provide a uniform measurement system throughout the PS complex. This paper discusses the solutions used and analyses the first beam measurement results.

  18. Yavuz Bülent Bâkiler’in “Seninle” Adlı Şiir Kitabının Söz Varlığı Vocabulary Of Yavuz Bülent Bakiler’s Poetry Book Called “ Seninle”

    Directory of Open Access Journals (Sweden)

    Gülşah PARLAK KALKAN

    2013-07-01

    ığı, bir dilde sadece bir takım seslerin bir araya gelmesiyle kurulmuş simgeler olarak değil, aynı zamanda o dili konuşan toplumun kavramlar dünyası, maddi ve manevi kültürünün yansıtıcısı, dünya görüşünün bir kesiti olarak da düşünülmelidir.Çalışmamıza konu olan Yavuz Bülent Bâkiler‟in “Seninle” adlı şiir kitabı içinde 30 adet şiir yer almaktadır. Bu şiirlerde toplam 3311 söz kullanılmıştır. Bu sözler öncelikle, “anlamlı kelimeler” ve “görevli kelimeler” olmaları bakımından asıl sözler ve yardımcı sözler şeklinde iki grupta incelenmiştir. Asıl sözler içerisinde isimler, sıfatlar, zamirler, zarflar, fiiller ve ikilemeler değerlendirilmiş; yardımcı sözler içerisinde ise çekim edatları, bağlama edatları, kuvvetlendirme edatları, soru edatları, ünlemler, karşılaştırma-denkleştirme edatları, cevap edatları vb. değerlendirilmiştir. Ayrıca her söz; asıl söz ya da yardımcı söz alma özelliliğine göre kategorize edildikten sonra bu sözlerin köken bilgileri ve somut-soyut olma durumları tespit edilmiştir. Diğer taraftan her grupta kullanım sıklığı en fazla olan sözler de belirtilmiştir.Bu çalışmada elde edilen verilerin yorumlanmasıyla şiirlerin kaleme alındığı dönemde kullanılan dilin özellikleri, dildeki yerli ve alıntı söz oranı, alıntıların en çok hangi dilden olduğu ve ayrıca şiirlerin vücuda geldiği toplumla ilgili ipuçları hakkında tespitlerde bulunulmuştur.

  19. Halit Fahri Ozansoy'un Gülistanlar ve Harabeler Adlı Eserinde Bahçe İmajları ve Renkler Garden Images and Colors in Halit Fahri Ozansoy’s Work of Gülistanlar ve Harabeler

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    Hüseyin DOĞRAMACIOĞLU

    2012-12-01

    Full Text Available Halit Fahri Ozansoy’s poetry books of Gülistanlar ve Harabeler printed with old letters but not transformed to the Latin alphabet until now. In his work, garden images and colors which loaded special meaning of poet was known as hidden pearls and no research have been made on this work till now. Garden images in poetry are sometimes colorful, light and sometimes dull and dark. These images change with the with the poet's spirit world. We can visualize the garden images like an oil painting. These images drawn by the poet's words, show poet’s mood like a mirror. The colors used in the poem vary with garden images. This change appears with the change of the mental status of the poet. Thus, the poet uses the colors in accordancewith the different tables and his mood. When there are a lively andwarm colors in optimistic tables, dark and dull colors chosen inpessimistic tables. The poet's choice of the colors is not a coincidence.This selectivity included to poetry with different sensations. In his work,Ozansoy has described variety of colors in different gardens.Imagination, imagery and various emotions had been made with oneaccord in his depictions. The colors and portraits of garden form thepoet’s imagination. Colorful memories in the garden which experiencedin a darling moves from poet's imagination to the verses of the poem.Imagination, colors and gardens are described with darling. Theseimageries compose the garden images and semantic change of thecolors. Halit Fahri Ozansoy’un Gülistanlar ve Harabeler adlı şiir kitabı eski harflerle basılmış ancak günümüze kadar Latin harflerine aktarılmamıştır. Bu eserde şairin bahçe imajları ve renklere yüklediği anlamlar saklı inciler gibi gizli kalmış ve günümüze kadar üzerinde inceleme yapılmamıştır. Şiirdeki bahçe imajları bazen renkli, ışıklı ve bazen de donuk ve karanlıktır. Şairin değişen ruh dünyası ile birlikte bu imajlar da değişir. Bah

  20. “Beyhude Ömrüm” Adlı Hikâyenin Greımas’ın Eyleyenler Modeline Göre İncelenmesi Analysıs Of Story “Beyhude Ömrüm” Accordıng To Greımas’ Actants Model

    Directory of Open Access Journals (Sweden)

    Hatice ALTUNKAYA

    2012-12-01

    önüştürmek, anlamsal bağlarını keşfetmek okurun işidir. Eski Yunancada gösterge anlamına gelen semeion ile bilim anlamına gelen logos sözcüğünün birleşmesiyle meydana gelen semology Türkçede gösterge bilimi terimiyle karşılanmaktadır.Göstergebilimin öncüleri olarak iki isimden söz etmek mümkündür. Bunlar Charles Sanders Peirce ve İsviçreli dilbilimci Ferdinand de Saussure’dür. Peirce, “Tüm evren, yalnızca göstergelerden oluşmamış olsa bile, göstergelerle dolup taşar” sözü ile bütün bilgi nesnelerinin göstergebilimin konusu olabileceğini ifade etmiştir.Bu çalışmada Mustafa Kutlu’nun “Beyhude Ömrüm” adlı hikâyesi göstergebilimsel bir çözümleme modeli olan Greimas’ın eyleyenler modeline göre incelenmeye çalışılmıştır. A.J. Greimas’a göre anlatının oluşabilmesi için öyküyü başlatacak bir olay ve bu başlangıç durumunu bozacak dönüştürücü ögeye ihtiyaç vardır. Çalışmada söz konusu olay ve dönüştürücü ögenin var olduğundan hareketle hikâye beş kesite ayrılmıştır. Bu kesitlerde eyleyenler modelinde bulunan altı eyleyenin bulunduğu, anlatı izlencesinden eyletim, edinç, edim ve yaptırım izlence evrelerinin yer aldığı tespit edilmiş ve eyleyenler modelindeki öznelerin yetilendirici, sonuçlandırıcı ve onurlandırıcı deneyimleri gerçekleştirdikleri görülmüştür. Ayrıca eserde ben anlatıcı olan yazarın “öldüm” ifadesini kullanmasının ben anlatıcının anlatımına uygun düşen bir anlatım olmadığı görülmüştür.

  1. 17. Yüzyıl Azerbaycan Sahasında Yazılan Hikayat Adlı Eserdeki Ünlü Uyumları Üzerine Bir İnceleme A Study On Vowel Harmony In Written Work Named Hikáyát In Azerbaijani Field In Seventeenth Century

    Directory of Open Access Journals (Sweden)

    Meltem GÜL

    2013-07-01

    rkçenin seslerini ifade etmedeki yetersizliğinden dolayı genellikle yabancı araştırmacıların yazmış olduğu transkripsiyon metinleri üzerinde araştırmalar yapılmıştır. Bu transkripsiyon metinleri kendi içlerinde bazı problemleri barındırmalarına rağmen Türkçe’nin tarihi için çok değerli kaynaklardır. Bu çalışmada 17. yüzyıl ünlü uyumları Hikāyāt adlı eser örneği üzerinde incelenerek dönemin özellikleriyle karşılaştırılmıştır. Öncelikle metinde hangi eklerin ünlü uyumunu bozduğu tespit edilmiştir. Uyuma aykırılıkların ne ölçüde olduğu belirtilip bu aykırılıklar sözcük kök ve gövdelerindeki aykırılıklar ve eklerde aykırılıklar olmak üzere ayrı başlıklar altında incelenmiştir.Bunun dışında büyük ünlü uyumunun tam olarak olup olmadığına bakılmıştır. Ayrıca 17. Yüzyılın en önemli ses olaylarından olan dudak uyumunun Hikāyāt metninde nasıl görüldüğü tespit edilmiştir. Uyuma aykırılıkların ne ölçüde olduğu belirlenmiştir. Düzleşme konusunda kurallı bir kullanımın olup olmadığı ortaya konulmuştur.17. yüzyıl Orta Osmanlıca dönemi bir geçiş dönemi olarak değerlendirilir. Eserde ünlü uyumlarında tam bir geçiş dönemi özelliklerinin görülüp görülmediği belirlenmiştir. Eklerin genel olarak nasıl kullanıldıkları belirlenmiştir.Ayrıca Azerbaycan sahasında yazılan bu eserle ünlü uyumu üzerinde Azerbaycan Türkçesinin etkilerini yansıtan ek kullanımları belirlenmeye çalışılarak Azerbaycan Türkçesiyle Türkiye Türkçesi arasındaki dil özelliklerinin farkları ortaya konulmuştur. Bu makale üzerinde çok sınırlı araştırmaların bulunduğu 17. yüzyıl Türkçesinin aydınlatılmasına katkı sağlayacaktır.

  2. Kirdeci Ali ve Dâstân-ı ‘Ömer İbni Hattâb Adlı Küçük Mesnevisi Kirdeci Ali and Kirdeci Ali’s Short Masnavi called Dâstân-ı Ömer İbni Hattâb

    Directory of Open Access Journals (Sweden)

    Halit BİLTEKİN

    2013-03-01

    olarak görmelerinde de dikkat çekici işlevler üstlenmiştir. Başlangıçta Kur’an ve surelerin çeviri ve tefsiri ile başlayan hizmet, daha sonra dinî, tasavvufî ve ahlakî manzum eserlerle devam etmiştir. Bu manzum eserlerin en çok görüldüğü dönemlerden biri XIV. yüzyıldır. Bu yüzyılda konuları dinî, ahlakî ve İslam kahramanlığı olan, küçük mesneviler şeklinde Geyik, Kesikbaş, G��vercin, Ejderha, gibi halkın dinî, ahlakî ve kahramanlık duygularına hitap eden eserler yazılmıştır. Bu eserlerin birçoğunun yazarı belli değildir. Bazılarının ise, eserin içinde geçen ismin yazar mı, yoksa söyleyen mi olduğu konusu belirsizdir. XIV. yüzyılda yaşadığı kabul edilen Kirdeci Alî de böyle şairlerden biridir. Kirdeci Alî’nin bugün elimizde edebiyat tarihinde yerini almış Kesikbaş Destanı, Güvercin Destanı ve Ejderha Destanı olmak üzere bilinen üç kısa mesnevisi vardır. Bunlar dışında Kirdeci Alî’ye izafe edilen Hikâye-i Delletü’l-muhtel, Geyik Destanı gibi mesneviler varsa da bunların ona aidiyeti şüphelidir. Kirdeci Alî’nin bugüne kadar kaynaklarda adı geçmeyen, bu çalışmada tanıtılacak olan Dâstân-ı Ömer İbni Hattâb adlı mesnevisi on beş beyitlik kısa bir mesnevidir. “fâ’ilâtün fâ’ilâtün fâ’ilün” kalıbıyla yazılan mesnevinin konusu Hz. Ömer ile bir “Yahudi” arasında geçen hikâyedir. Bu kısa mesnevide Hz. Ömer vasıtası ve Tanrı’nın takdiriyle bir Yahudi topluluğunun Müslümanlığı kabul etmesi olayı anlatılmaktadır.

  3. Injecting Formal Verification in FMI-based Co-Simulations of Cyber-Physical Systems

    DEFF Research Database (Denmark)

    Couto, Luis Diogo; Basagiannis, Stylianos; Ridouane, El Hassan

    2017-01-01

    This publication is part of the Horizon 2020 project: Integrated Tool chain for model-based design of CPSs (INTO-CPS), project/GA number 644047.......This publication is part of the Horizon 2020 project: Integrated Tool chain for model-based design of CPSs (INTO-CPS), project/GA number 644047....

  4. Model documentation coal market module of the National Energy Modeling System

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the Coal Production Submodule (CPS). It provides a description of the CPS for model analysts and the public. The Coal Market Module provides annual forecasts of prices, production, and consumption of coal.

  5. Model documentation coal market module of the National Energy Modeling System

    International Nuclear Information System (INIS)

    1997-02-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the Coal Production Submodule (CPS). It provides a description of the CPS for model analysts and the public. The Coal Market Module provides annual forecasts of prices, production, and consumption of coal

  6. [Governance in a project addressing care of disabled elderly persons within the regional healthcare system of Tuscany, Italy].

    Science.gov (United States)

    Pedace, Claudio; Rosa, Antonella; Francesconi, Paolo; Acampora, Anna; Ricciardi, Walter; Damiani, Gianfranco

    2017-01-01

    Population aging and the concurrent increase of age-related chronic degenerative diseases and disability are associated with an increased proportion of elderly persons who are dependent in activities of daily living (ADL). ADL-dependent persons need continuous and long-term health and social care according to the "taking charge" rationale, in order to warrant access and continuity of care. A healthcare system needs to respond to the long-term and complex needs, such as those of disabled elderly people, by providing appropriate health and social care services in Primary Care. A Primary Health Care system is organized according to two governance levels have distinct aims but are closely inter-dependent in their operational mechanisms. The system governance is accountable for the community and individual health protection while the delivery governance is accountable for the provision of services in accordance with appropriateness, safety and economic criteria. Delivery governance can be considered "integrated governance" as a synergy exists between two decision-making systems guiding provider choices, which are corporate governance and clinical governance. The aim of this study was to analyse the abovementioned governance levels within the healthcare system in Tuscany (Italy) referring to long-term residential care for disabled elderly people. The case of excessive accesses to emergency departments from different types of Nursing Homes (NH) is used as an example to analyse different levels of responsibility involved in the management of a critical phenomenon. Suggestions for improvement in the different levels of governance for disabled elderly people are provided, in order to support institutional programming activities.

  7. Design-related influencing factors of the computerized procedure system for inclusion into human reliability analysis of the advanced control room

    International Nuclear Information System (INIS)

    Kim, Jaewhan; Lee, Seung Jun; Jang, Seung Cheol; Ahn, Kwang-Il; Shin, Yeong Cheol

    2013-01-01

    This paper presents major design factors of the computerized procedure system (CPS) by task characteristics/requirements, with individual relative weight evaluated by the analytic hierarchy process (AHP) technique, for inclusion into human reliability analysis (HRA) of the advanced control rooms. Task characteristics/requirements of an individual procedural step are classified into four categories according to the dynamic characteristics of an emergency situation: (1) a single-static step, (2) a single-dynamic and single-checking step, (3) a single-dynamic and continuous-monitoring step, and (4) a multiple-dynamic and continuous-monitoring step. According to the importance ranking evaluation by the AHP technique, ‘clearness of the instruction for taking action’, ‘clearness of the instruction and its structure for rule interpretation’, and ‘adequate provision of requisite information’ were rated as of being higher importance for all the task classifications. Importance of ‘adequacy of the monitoring function’ and ‘adequacy of representation of the dynamic link or relationship between procedural steps’ is dependent upon task characteristics. The result of the present study gives a valuable insight on which design factors of the CPS should be incorporated, with relative importance or weight between design factors, into HRA of the advanced control rooms. (author)

  8. Far-IR transparency and dynamic infrared signature control with novel conducting polymer systems

    Science.gov (United States)

    Chandrasekhar, Prasanna; Dooley, T. J.

    1995-09-01

    Materials which possess transparency, coupled with active controllability of this transparency in the infrared (IR), are today an increasingly important requirement, for varied applications. These applications include windows for IR sensors, IR-region flat panel displays used in camouflage as well as in communication and sight through night-vision goggles, coatings with dynamically controllable IR-emissivity, and thermal conservation coatings. Among stringent requirements for these applications are large dynamic ranges (color contrast), 'multi-color' or broad-band characteristics, extended cyclability, long memory retention, matrix addressability, small area fabricability, low power consumption, and environmental stability. Among materials possessing the requirements for variation of IR signature, conducting polymers (CPs) appear to be the only materials with dynamic, actively controllable signature and acceptable dynamic range. Conventional CPs such as poly(alkyl thiophene), poly(pyrrole) or poly(aniline) show very limited dynamic range, especially in the far-IR, while also showing poor transparency. We have developed a number of novel CP systems ('system' implying the CP, the selected dopant, the synthesis method, and the electrolyte) with very wide dynamic range (up to 90% in both important IR regions, 3 - 5 (mu) and 8 - 12 (mu) ), high cyclability (to 105 cycles with less than 10% optical degradation), nearly indefinite optical memory retention, matrix addressability of multi-pixel displays, very wide operating temperature and excellent environmental stability, low charge capacity, and processability into areas from less than 1 mm2 to more than 100 cm2. The criteria used to design and arrive at these CP systems, together with representative IR signature data, are presented in this paper.

  9. A hydroxyl radical detection system using gas expansion and fast gating laser-induced fluorescence techniques.

    Science.gov (United States)

    Chen, Hao; Hu, Renzhi; Xie, Pinhua; Xing, Xingbiao; Ling, Liuyi; Li, Zhiyan; Wang, Fengyang; Wang, Yihui; Liu, Jianguo; Liu, Wenqing

    2018-03-01

    An OH radical measurement instrument based on Fluorescence Assay by Gas Expansion (FAGE) has been developed in our laboratory. Ambient air is introduced into a low-pressure fluorescence cell through a pinhole aperture and irradiated by a dye laser at a high repetition rate of 8.5kHz. The OH radical is both excited and detected at 308nm using A-X(0,0) band. To satisfy the high efficiency needs of fluorescence collection and detection, a 4-lens optical system and a self-designed gated photomultiplier (PMT) is used, and gating is actualized by switching the voltage applied on the PMT dynodes. A micro channel photomultiplier (MCP) is also prepared for fluorescence detection. Then the weak signal is accumulated by a photon counter in a specific timing. The OH radical excitation spectrum range in the wavelength of 307.82-308.2nm is detected and the excited line for OH detection is determined to be Q 1 (2) line. The calibration of the FAGE system is researched by using simultaneous photolysis of H 2 O and O 2 . The minimum detection limit of the instrument using gated PMT is determined to be 9.4×10 5 molecules/cm 3 , and the sensitivity is 9.5×10 -7 cps/(OH·cm -3 ), with a signal-to-noise ratio of 2 and an integration time of 60sec, while OH detection limit and the detection sensitivity using MCP is calculated to be 1.6×10 5 molecules/cm 3 and 2.3×10 -6 cps/(OH·cm -3 ). The laboratory OH radical measurement is carried out and results show that the proposed system can be used for atmospheric OH radical measurement. Copyright © 2017. Published by Elsevier B.V.

  10. Tahsin Ömer’in “Darb-I Mesellerimiz Hakkında Tahlili Tedkikat” Adlı Atasözleri Seçkisi A Selection of Proverbs from Tahsin Ömer’s “Darb-ı Mesellerimiz Hakkında Tahlili Tedkikat”

    Directory of Open Access Journals (Sweden)

    Abdulmuttalip İPEK

    2012-09-01

    foreword. Atasözleri ve deyimler, toplumların uzun süren gözlem, deneyim ve yaşantılarına dayandığından; ait oldukları toplumun yaşama biçiminden düşünce yapısına, değer yargılarından ahlâk anlayışına varıncaya kadar çok değişik konuları içerirler. Bu nedenle bir milletin bütün kültür ve değerler dünyasının özü mesabesinde olan kalıplaşmış sözlerdir. İletişim esnasında kısa, kestirme ve etkili bir anlatımı mümkün kılan atasözleri, aynı zamanda bir milletin felsefesini de yansıtır. Bu bakımdan bu söz varlıklarının bilinmesi ve yaşatılması hayatî önem arz etmektedir. Türk dilinin bilinen en eski sözlüğü olan Divânü Lügati’t-Türk’ten günümüze değin bu söz varlıklarını yaşatma ve kayıt altına alma amacına yönelik önemli sözlükler kaleme alınmıştır. Bunların her biri Türk dili ve kültürü açısından birbirinden değerli kaynaklardır. Bu makalede, yapılan taramalar ve araştırmalar neticesinde, bugüne kadar –bir iki yazı dışında– varlığından söz edilmemiş bir atasözü seçkisi üzerinde durulacaktır. 1337-1340 (M. 1921 yıllarında İstanbul Şehzâdebaşı’ndaki Evkâf Matbaası’nda basılan ve Tahsin Ömer tarafından kaleme alınmış olan “Darb-ı Mesellerimiz Hakkında Tahlîlî Tedkîkât” adlı risalenin, Toronto Üniversitesi Kütüphanesi’nde PN 6505 T8 035 numarada kayıtlı, eski harfli matbu nüshası kısa bir değerlendirme ilave edilerek yeni yazıya çevrilmiştir. Tahsin Ömer’in iki buçuk sayfalık mukaddimede belirttiği üzere bu eser, memleketimizde kullanılan beş bine yakın darbımeselin birer birer tetkiki neticesinde toplanan iki yüze yakın sözün, sahip olduğu manalar itibariyle ayrı ayrı kadrolar halinde tasnif edilip, halkın çeşitli dersler çıkarması ve ibret alması amacıyla kaleme alınmış 16 sayfalık bir risaledir. Pek hacimli olmayan bu risalenin en dikkate değer tarafı müellifinin darb

  11. Recent progress of China HCCB TBM tritium system

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Deli, E-mail: luodeli2005@hotmail.com; Huang, Guoqiang; Huang, Zhiyong; Qin, Cheng; Song, Jiangfeng; He, Kanghao; Chen, Chang’an; Zhang, Guikai; Fu, Jun; Yao, Yong; An, Yongtao

    2016-11-01

    Highlights: • Comparing with our previous design, improvements have been made according to the up-to-date experiments and simulations: (1) The palladium alloy tube in the previous design is now removed in the upgraded one and the cryogenic molecular sieve bed is replaced by the getter bed to reduce tritium inventory; (2) Hot metal reduction bed is relocated from T-Plant to Port Cell; (3) TAS is now integrated into TES. • The proposed coolant purification is based on catalytic oxidation and molecular sieve bed adsorption for tritium removal, as well as hot metal adsorption for the elimination of non-tritium gaseous impurities. Some operation parameters and functional components are improved. The interface with the high pressure HCS and other plant systems was incorporated taking into account of the requirement from the ITER port management group meetings. - Abstract: China tritium system including Tritium Extraction System (TES) with Tritium Accountancy System (TAS) integrated in and Coolant Purification System (CPS), which is subordinate to Helium Coolant System (HCS), is of great importance for China Helium Cooled Ceramic Breeder Test Blanket Module (CN HCCB TBM). The purge gas (99.9% He + 0.1% H{sub 2}) carrying Q{sub 2}O (Q = H, D, T) and Q{sub 2} from Li{sub 4}SiO{sub 4} ceramic breeder flows through the reduction bed where Q{sub 2}O is reduced into Q{sub 2} and then absorbed by the getter bed. The HT/HTO ratio and the total tritium are determined by TAS. Catalytic oxidation combines with molecular sieve absorption and hot metal purification are applied to remove tritium and other impurities in helium coolant. A loop including depressurization, helium-sweeping assisted thermal desorption, and cold trapping for the regeneration of saturated molecular sieve bed until the concentration of the desorbed Q{sub 2}O is reduced to an acceptable level. This paper introduces the recent progress of China tritium system including updated conceptual designs of TES and

  12. Performance evaluation of continuous blood sampling system for PET study. Comparison of three detector-systems

    CERN Document Server

    Matsumoto, K; Sakamoto, S; Senda, M; Yamamoto, S; Tarutani, K; Minato, K

    2002-01-01

    To measure cerebral blood flow with sup 1 sup 5 O PET, it is necessary to measure the time course of arterial blood radioactivity. We examined the performance of three different types of continuous blood sampling system. Three kinds of continuous blood sampling system were used: a plastic scintillator-based beta detector (conventional beta detector (BETA)), a bismuth germinate (BGO)-based coincidence gamma detector (Pico-count flow-through detector (COINC)) and a Phoswich detector (PD) composed by a combination of plastic scintillator and BGO scintillator. Performance of these systems was evaluated for absolute sensitivity, count rate characteristic, sensitivity to background gamnra photons, and reproducibility for nylon tube geometry. The absolute sensitivity of the PD was 0.21 cps/Bq for sup 6 sup 8 Ga positrons at the center of the detector. This was approximately three times higher than BETA, two times higher than COINC. The value measured with BETA was stable, even when background radioactivity was incre...

  13. Integrating Solar PV in Utility System Operations

    Energy Technology Data Exchange (ETDEWEB)

    Mills, A.; Botterud, A.; Wu, J.; Zhou, Z.; Hodge, B-M.; Heany, M.

    2013-10-31

    relative to DA forecasts, but still imperfect. Finally, we represent decisions within the operating hour by schedulers and transmission system operators as real-time (RT) balancing. We simulate the DA and HA scheduling processes with a detailed unit-commitment (UC) and economic dispatch (ED) optimization model. This model creates a least-cost dispatch and commitment plan for the conventional generating units using forecasts and reserve requirements as inputs. We consider only the generation units and load of the utility in this analysis; we do not consider opportunities to trade power with neighboring utilities. We also do not consider provision of reserves from renewables or from demand-side options. We estimate dynamic reserve requirements in order to meet reliability requirements in the RT operations, considering the uncertainty and variability in load, solar PV, and wind resources. Balancing reserve requirements are based on the 2.5th and 97.5th percentile of 1-min deviations from the HA schedule in a previous year. We then simulate RT deployment of balancing reserves using a separate minute-by-minute simulation of deviations from the HA schedules in the operating year. In the simulations we assume that balancing reserves can be fully deployed in 10 min. The minute-by-minute deviations account for HA forecasting errors and the actual variability of the load, wind, and solar generation. Using these minute-by-minute deviations and deployment of balancing reserves, we evaluate the impact of PV on system reliability through the calculation of the standard reliability metric called Control Performance Standard 2 (CPS2). Broadly speaking, the CPS2 score measures the percentage of 10-min periods in which a balancing area is able to balance supply and demand within a specific threshold. Compliance with the North American Electric Reliability Corporation (NERC) reliability standards requires that the CPS2 score must exceed 90% (i.e., the balancing area must maintain adequate

  14. Application of Monte Carlo techniques for standardless efficiency calibration of NaI(Tl) based gamma spectrometry system

    International Nuclear Information System (INIS)

    Verma, Amit K.; Anilkumar, S.; Narayani, K.; Babu, D.A.R.; Sharma, D.N.

    2012-01-01

    The gamma ray spectrometry technique is commonly used for the assessment of radioactivity in environmental matrices like water, soil, vegetation etc. The detector system used for gamma ray spectrometer should be calibrated for each geometry considered and for different gamma energies. It is very difficult to have radionuclide standards to cover all photon energies and also not feasible to make standard geometries for common applications. So there is a need to develop some computational techniques to determine absolute efficiencies of these detectors for practical geometries and for energies of common radioactive sources. A Monte Carlo based simulation method is proposed to study the response of the detector for various energies and geometries. From the simulated spectrum it is possible to calculate the efficiency of the gamma energy for the particular geometry modeled. The efficiency calculated by this method has to be validated experimentally using standard sources in laboratory conditions for selected geometries. For the present work simulation studies were under taken for the 3″ x 3″ NaI(Tl) detector based gamma spectrometry system set up in our laboratory. In order to see the effectiveness of the method for the low level radioactivity measurement it is planned to use low active standard source of 40 K in cylindrical container geometry for our work. Suitable detector and geometry model was developed using KCI standard of the same size, composition, density and radionuclide contents. Simulation data generated was compared with the experimental spectral data taken for a counting period of 20000 sec and 50000 sec. The peak areas obtained from the simulated spectra were compared with that of experimental spectral data. It was observed that the count rate (9.03 cps) in the simulated peak area is in agreement with that of the experimental peak area count rates (8.44 cps and 8.4 cps). The efficiency of the detector calculated by this method offers an alternative

  15. A digital autoradiography system based on the Medipix2 chip: images of {sup 3}H and {sup 14}C microscales

    Energy Technology Data Exchange (ETDEWEB)

    Mettivier, Giovanni; Montesi, Maria C. E-mail: montesi@na.infn.it; Russo, Paolo

    2004-02-01

    In the framework of the MAMA project, funded by INFN, we have assembled a digital imaging system for beta and gamma autoradiography based on the Medipix2 single photon counting read-out chip bump-bonded to a 300 {mu}m thick silicon pixel detector. This system has 256x256 square pixels of 55 {mu}m pitch for a total sensitive area of 14x14 mm{sup 2}. Each pixel contains two discriminators and a 13-bit counter. The detection threshold is about 6 keV and a noise is about 10{sup -3} cps/mm{sup 2}. Real time images have been obtained of {sup 3}H and {sup 14}C autoradiographic scales. The minimum detectable activity is 0.32 Bq in 14 h for {sup 3}H and 0.012 Bq in 10 h for {sup 14}C.

  16. MONICA: a compact, portable dual gamma camera system for mouse whole-body imaging

    International Nuclear Information System (INIS)

    Xi, Wenze; Seidel, Jurgen; Kakareka, John W.; Pohida, Thomas J.; Milenic, Diane E.; Proffitt, James; Majewski, Stan; Weisenberger, Andrew G.; Green, Michael V.; Choyke, Peter L.

    2010-01-01

    Introduction: We describe a compact, portable dual-gamma camera system (named 'MONICA' for MObile Nuclear Imaging CAmeras) for visualizing and analyzing the whole-body biodistribution of putative diagnostic and therapeutic single photon emitting radiotracers in animals the size of mice. Methods: Two identical, miniature pixelated NaI(Tl) gamma cameras were fabricated and installed 'looking up' through the tabletop of a compact portable cart. Mice are placed directly on the tabletop for imaging. Camera imaging performance was evaluated with phantoms and field performance was evaluated in a weeklong In-111 imaging study performed in a mouse tumor xenograft model. Results: Tc-99m performance measurements, using a photopeak energy window of 140 keV±10%, yielded the following results: spatial resolution (FWHM at 1 cm), 2.2 mm; sensitivity, 149 cps (counts per seconds)/MBq (5.5 cps/μCi); energy resolution (FWHM, full width at half maximum), 10.8%; count rate linearity (count rate vs. activity), r 2 =0.99 for 0-185 MBq (0-5 mCi) in the field of view (FOV); spatial uniformity, <3% count rate variation across the FOV. Tumor and whole-body distributions of the In-111 agent were well visualized in all animals in 5-min images acquired throughout the 168-h study period. Conclusion: Performance measurements indicate that MONICA is well suited to whole-body single photon mouse imaging. The field study suggests that inter-device communications and user-oriented interfaces included in the MONICA design facilitate use of the system in practice. We believe that MONICA may be particularly useful early in the (cancer) drug development cycle where basic whole-body biodistribution data can direct future development of the agent under study and where logistical factors, e.g., limited imaging space, portability and, potentially, cost are important.

  17. Segregation and Inequality in Chicago Public Schools, Transformed and Intensified under Corporate Education Reform

    Science.gov (United States)

    Jankov, Pavlyn; Caref, Carol

    2017-01-01

    During the period of 1981 to 2015, the total population of Black students in CPS plummeted from close to 240,000, 60% of all CPS students, to 156,000 or 39% of CPS. This paper documents how despite their decreasing numbers and percentage in the system, the vast majority of Black students remained isolated in predominantly low-income Black schools…

  18. Output Feedback Controller Design with Symbolic Observers for Cyber-physical Systems

    Directory of Open Access Journals (Sweden)

    Masashi Mizoguchi

    2016-12-01

    Full Text Available In this paper, we design a symbolic output feedback controller of a cyber-physical system (CPS. The physical plant is modeled by an infinite transition system. We consider the situation that a finite abstracted system of the physical plant, called a c-abstracted system, is given. There exists an approximate alternating simulation relation from the c-abstracted system to the physical plant. A desired behavior of the c-abstracted system is also given, and we have a symbolic state feedback controller of the physical plant. We consider the case where some states of the plant are not measured. Then, to estimate the states with abstracted outputs measured by sensors, we introduce a finite abstracted system of the physical plant, called an o-abstracted system, such that there exists an approximate simulation relation. The relation guarantees that an observer designed based on the state of the o-abstracted system estimates the current state of the plant. We construct a symbolic output feedback controller by composing these systems. By a relation-based approach, we proved that the controlled system approximately exhibits the desired behavior.

  19. Development and Operation of a High Resolution Positron Emission Tomography System to Perform Metabolic Studies on Small Animals.

    Science.gov (United States)

    Hogan, Matthew John

    A positron emission tomography system designed to perform high resolution imaging of small volumes has been characterized. Two large area planar detectors, used to detect the annihilation gamma rays, formed a large aperture stationary positron camera. The detectors were multiwire proportional chambers coupled to high density lead stack converters. Detector efficiency was 8%. The coincidence resolving time was 500 nsec. The maximum system sensitivity was 60 cps/(mu)Ci for a solid angle of acceptance of 0.74(pi) St. The maximum useful coincidence count rate was 1500 cps and was limited by electronic dead time. Image reconstruction was done by performing a 3-dimensional deconvolution using Fourier transform methods. Noise propagation during reconstruction was minimized by choosing a 'minimum norm' reconstructed image. In the stationary detector system (with a limited angle of acceptance for coincident events) statistical uncertainty in the data limited reconstruction in the direction normal to the detector surfaces. Data from a rotated phantom showed that detector rotation will correct this problem. Resolution was 4 mm in planes parallel to the detectors and (TURN)15 mm in the normal direction. Compton scattering of gamma rays within a source distribution was investigated using both simulated and measured data. Attenuation due to scatter was as high as 60%. For small volume imaging the Compton background was identified and an approximate correction was performed. A semiquantitative blood flow measurement to bone in the leg of a cat using the ('18)F('-) ion was performed. The results were comparable to investigations using more conventional techniques. Qualitative scans using ('18)F labelled deoxy -D-glucose to assess brain glucose metabolism in a rhesus monkey were also performed.

  20. Development of bremsstrahlung detection type tritium gas monitoring system, (1)

    International Nuclear Information System (INIS)

    Bingo, Kazuyoshi; Yoshida, Makoto; Chida, Tohru; Kawasaki, Katsuya

    1982-11-01

    A tritium monitoring system by means of bremsstrahlung detecting was developed. A prototype system consisted of a sampling cylinder, a gas circulating apparatus, an NaI(T1) detector, an amplifier and a multichannel analyzer. The sizes of sampling cylinders used 208 mm phi x 290; 170; 70 mmH, 133 mm phi x 292; 172; 72 mmH and 55 mm phi x 294; 174; 74 mmH, respectively. The sensitivity of prototype system was from 12 to 57 cps/μCi.cm - 3 , depending on the size of sampling cylinder and an efficiency of NaI(T1) detector. When pulses due to breamsstrahlungs with energy from 4 to 17 keV were counted, the minimum detectable concentration of the prototype tritium monitoring system was obtained to be 5.2 x 10 - 3 μCi/cm 3 . It was evaluated that the detectable range of concentration was from 1 x 10 - 2 to 1 x 10 3 μCi/cm 3 . (author)

  1. Crosslinked plastic scintillators: A new detection system for radioactivity measurement in organic and aggressive media

    International Nuclear Information System (INIS)

    Bagán, Héctor; Tarancón, Alex; Ye, Lei; García, José F.

    2014-01-01

    Highlights: • A crosslinked plastic scintillatior for radioactivity measurement was developed. • The effect of C-PS composition in the detection efficiency was evaluated. • C-PS permits the measurement of radioactivity in organic and aggressive media. • C-PS exhibits high detection efficiency in water and even higher in organic media. • C-PS exhibits good reproducibility under different polymerisations with elevated yield. - Abstract: The measurement of radioactive solutions containing organic or aggressive media may cause stability problems in liquid and plastic scintillation (PS) techniques. In the case of PS, this can be overcome by adding a crosslinker to the polymer structure. The objectives of this study are to synthesise a suitable crosslinked plastic scintillator (C-PS) for radioactivity determination in organic and aggressive media. The results indicated that an increase in the crosslinker content reduces the detection efficiency and a more flexible crosslinker yields higher detection efficiency. For the polymer composition studied, 2,5-diphenyloxazole (PPO) is the most adequate fluorescent solute and an increase in its concentration causes little change in the detection efficiency. The inclusion of a secondary fluorescent solute 1,4-bis-2-(5-phenyloxazolyl) benzene (POPOP) improves the C-PS radiometrical characteristics. For the final composition chosen, the synthesis of the C-PS exhibits good reproducibility with elevated yield. The obtained C-PS also displays high stability in different organic (toluene, hydrotreated vegetable oil (HVO) and methanol) and aggressive media (hydrochloric acid, nitric acid and hydrogen peroxide). Finally, the C-PS exhibits high detection efficiency both in water and in aggressive media and can also be applied in organic media showing similar or even higher detection efficiency values

  2. Title IV-E Child Welfare Training and University Partnerships: Transforming State Child Protection Services into a Trauma-Informed System

    Directory of Open Access Journals (Sweden)

    Robin Hernandez-Mekonnen

    2017-09-01

    Full Text Available Children who are involved in the child welfare system have experienced trauma, and research indicates that parents of those children also frequently grapple with their own unresolved trauma. In addition, child welfare workers face high rates of secondary traumatic stress. Federal legislation from 2011 requires states to conduct universal trauma screening on children in foster care. The Administration on Children and Families (ACF urges state Child Protection agencies (CPS to become trauma-informed, however, many states still struggle to integrate a trauma focused practice model. This article describes the outcomes of a national, empirically driven, Core Concepts in Child Trauma for Child Welfare curriculum utilized in a Title IV-E university partnership program to teach graduate level child welfare agency supervisors. Findings suggest that the graduate trauma course demonstrates statistically significant gains in confidence, and also has a profound impact on the agency’s transformation into a trauma-informed system

  3. George Orwell’in ‘Bin Dokuz Yüz Seksen Dört’ Adlı Romanı İle Cengiz Aytmatov’un ‘Gün Olur Asra Bedel’ Adlı Romanının ‘Düşüncesuçu’ Bağlamında Karşılaştırılması Comparison Of The Novel Of George Orwell Called ‘Bın Dokuz Yuz Seksen Dort’ And Novel Of Cengiz Aytmatov Called ‘Gun Olur Asra Bedel’ Within The Context Of ‘Thoughtcrime’

    Directory of Open Access Journals (Sweden)

    Feyza İSLAMOĞLU

    2013-09-01

    Full Text Available Gün Olur Asra Bedel, in which Cengiz Aytmatov told about past,present and future of life that are three separated period of timenarrated ironically vision of world in which unrighteously and monotonylife have been imposed on, dealing with mind evanescence that iscommon result for all mentioned period, different time and conditions.And Bin Dokuz Yüz Seksen Dört, novel of George Orwell who is one ofthe important writers of English literature, mentioned about struggle ofdemanding justice and rustiness of consciousness that is the result ofbeing subjected to sovereign and criticised that the pressure of themanagement on people and its regime tried to carry out. Oppressiveregime and injustice that are the common subject in both of the novels,impossed physical or mental rustiness of people as solution. In thenovels, the system defending that the people must struggle just to keepthe state alive and banning any autonomous thought and behaviourhas been criticized. Mentioned system abolished free thought andprivacy completely, put machine system that has been directed bysovereign to the centre of life and imposed standart mentality. BinDokuz Yüz Seksen Dört that is a dystopia stray from Gün Olur AsraBedel by virtue of its this structure.Both of the novels that attract attention in parallelism of historicalprocess, dealed with thoughtcrime and presented similar results indifferent conditions. In this study it has been tried to researchsimilarities and differentnesses in Bin Dokuz Yüz Seksen Dört that is adystopia and Gün Olur Asra Bedel that includes utopia in it within theframe of causation. Cengiz Aytmatov’un, hayatın dünü, bugünü ve yarını şeklindeki üç ayrı zaman dilimini kaleme aldığı eseri Gün Olur Asra Bedel, söz konusu her dönem için, değişik zaman ve şartlarda tezahür eden zihin buharlaşmasını ele alarak, adaletsizce ve tekdüze yaşam sürdürmenin empoze edildiği dünya görüşünü ironik bir dille anlatm

  4. Control server for the PS orbit acquisition system Status 2009

    CERN Document Server

    Bart-Pedersen, S; CERN. Geneva. BE Department

    2009-01-01

    CERN’s Proton Synchrotron (CPS) has been fitted with a new Trajectory Measurement System (TMS). Analogue signals from forty Beam Position Monitors (BPM) are digitized at 125 MS/s, and then further treated in the digital domain to derive positions of all individual particle bunches on the fly. Large FPGAs are used to handle the digital processing. The system fits in fourteen plug-in modules distributed over three half-width cPCI crates that store data in circular buffers. They are connected to a Linux computer by means of a private Gigabit Ethernet segment. Dedicated server software, running under Linux, knits the system into a coherent whole [1]. The corresponding low-level software using FESA (BPMOPS class) was implemented while respecting the standard interface for beam position measurements. The BPMOPS server publishes values on request after data extraction and conversion from the TMS server. This software is running on a VME Lynx-OS platform and through dedicated electronics it can therefore control th...

  5. 77 FR 58510 - Proposed Information Collection; Comment Request; Current Population Survey (CPS), Annual Social...

    Science.gov (United States)

    2012-09-21

    ... especially sensitive to economic fluctuations. Economists use ASEC data to determine the effects of various economic forces, such as inflation, recession, recovery, and so on, and their differential effects on...

  6. Tobacco Use Supplement to the Current Population Survey (TUS-CPS) Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — 1992-1993, 1995-1996, 1998-1999, 2001-2002, 2003, 2006-2007, 2010-2011, 2014-2015. Centers for Disease Control and Prevention (CDC). State Tobacco Activities...

  7. 78 FR 45910 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Email Address...

    Science.gov (United States)

    2013-07-30

    ..., keep up response rates while lowering costs of interviewing. Internet is not limited to just a survey... respondent to set up a time to meet with the interviewer at their convenience and save on travel costs... Cost: The only cost to the respondents is that of their time. Respondents Obligation: Voluntary. Legal...

  8. 2016 Summer California Current Ecosystem CPS Survey (RL1606, EK60)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The cruise sampled the California Current Ecosystem from San Diego, CA to Vancouver Island, BC, CA. Multi-frequency (18-, 38-, 70-, 120-, 200-, and 333-) General...

  9. 77 FR 21526 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) School...

    Science.gov (United States)

    2012-04-10

    ... The Census Bureau plans to request clearance for the collection of data concerning the School... progress in school. II. Method of Collection The school enrollment information will be collected by both... interviews are conducted using computer- assisted interviewing. III. Data OMB Control Number: 0607-0464. Form...

  10. 76 FR 3610 - Proposed Information Collection; Comment Request; Current Population Surveys (CPS)-Housing...

    Science.gov (United States)

    2011-01-20

    ... HVS data to analyze market trends and for economic forecasting. II. Method of Collection Field... questions) and BC-1428RV (Brochure--The U.S. Census Bureau Respects Your Privacy and Keeps Your Personal...

  11. Data Series Generation for CPS Plants Simulation; Generacion de Series para Simulacion de Centrales Termosolares

    Energy Technology Data Exchange (ETDEWEB)

    Ibanez, G.; Valenzuela, R. X.; Ramirez, L.; Polo, J.

    2014-02-01

    Due to the problems with the environment and other issues arising from the use of oil as the main source of energy, such as unstable politics and economics, there has been a growing interest in the development of alternative forms of energy over the last few years. In this field, the sun is a fundamental element, since any form of existing energy derives from it, directly or indirectly. Taking in to consideration all of these renewable energies, we have decided to focus on solar thermal energy, seeing as it will play a vital role in the future particularly in countries such as Spain that have great solar potential. Amid this form of renewable energy, the parabolic cylinder concentrator power plants are technologies with one of the most promising futures. Power plants with sufficient technological developments to compete with the other forms of energies and that have an extensive margin for improvement. These power plants are the subject of the investigations carried out in this project. This project will try to establish and standardize some of the necessary procedures for the process of data prior to the simulation of energy with these types of power plants. The final objective is to help create a regulation where all these procedures are gathered together, and one that can be used as a guide for future investigations on the viability of these power plants. To achieve this, this project is comprised of various phases where different necessary investigations will be carried out in order to define the different points of the regulation. Firstly, the different casuistries will be investigated when analyzing the behavior of the estimated input data. At this stage, the selected variable (global or direct radiation), as well as the procedure used for the generation of the Monthly Reference Value, will be taken in to account, differentiating it in to two different typologies. The best method for the adjustment of the estimated data obtained from the satellite images will also be investigated, proposing the incorporation of a new method for it, as well as trying to determine whether it is equivalent to the one already established. Lastly, a simulation will be completed with the estimated data already processed in order to evaluate the influence of different alternatives and methods set out in the results, allowing for the comparison of these results with other simulations carried out with the measured data. (Author)

  12. 2016 Summer California Current Ecosystem CPS Survey (RL1606, EK80)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The cruise sampled the California Current Ecosystem from San Diego, CA to Vancouver Island, BC, CA. Multi-frequency (18-, 38-, 70-, 120-, 200-, and 333-) General...

  13. Acceptance/operational test procedure 101-AW tank camera purge system and 101-AW video camera system

    International Nuclear Information System (INIS)

    Castleberry, J.L.

    1994-01-01

    This procedure will document the satisfactory operation of the 101-AW Tank Camera Purge System (CPS) and the 101-AW Video Camera System. The safety interlock which shuts down all the electronics inside the 101-AW vapor space, during loss of purge pressure, will be in place and tested to ensure reliable performance. This procedure is separated into four sections. Section 6.1 is performed in the 306 building prior to delivery to the 200 East Tank Farms and involves leak checking all fittings on the 101-AW Purge Panel for leakage using a Snoop solution and resolving the leakage. Section 7.1 verifies that PR-1, the regulator which maintains a positive pressure within the volume (cameras and pneumatic lines), is properly set. In addition the green light (PRESSURIZED) (located on the Purge Control Panel) is verified to turn on above 10 in. w.g. and after the time delay (TDR) has timed out. Section 7.2 verifies that the purge cycle functions properly, the red light (PURGE ON) comes on, and that the correct flowrate is obtained to meet the requirements of the National Fire Protection Association. Section 7.3 verifies that the pan and tilt, camera, associated controls and components operate correctly. This section also verifies that the safety interlock system operates correctly during loss of purge pressure. During the loss of purge operation the illumination of the amber light (PURGE FAILED) will be verified

  14. Finite Energy and Bounded Actuator Attacks on Cyber-Physical Systems

    Energy Technology Data Exchange (ETDEWEB)

    Djouadi, Seddik M [ORNL; Melin, Alexander M [ORNL; Ferragut, Erik M [ORNL; Laska, Jason A [ORNL; Dong, Jin [ORNL; Drira, Anis [ORNL

    2015-01-01

    As control system networks are being connected to enterprise level networks for remote monitoring, operation, and system-wide performance optimization, these same connections are providing vulnerabilities that can be exploited by malicious actors for attack, financial gain, and theft of intellectual property. Much effort in cyber-physical system (CPS) protection has focused on protecting the borders of the system through traditional information security techniques. Less effort has been applied to the protection of cyber-physical systems from intelligent attacks launched after an attacker has defeated the information security protections to gain access to the control system. In this paper, attacks on actuator signals are analyzed from a system theoretic context. The threat surface is classified into finite energy and bounded attacks. These two broad classes encompass a large range of potential attacks. The effect of theses attacks on a linear quadratic (LQ) control are analyzed, and the optimal actuator attacks for both finite and infinite horizon LQ control are derived, therefore the worst case attack signals are obtained. The closed-loop system under the optimal attack signals is given and a numerical example illustrating the effect of an optimal bounded attack is provided.

  15. Secure estimation, control and optimization of uncertain cyber-physical systems with applications to power networks

    Science.gov (United States)

    Taha, Ahmad Fayez

    Transportation networks, wearable devices, energy systems, and the book you are reading now are all ubiquitous cyber-physical systems (CPS). These inherently uncertain systems combine physical phenomena with communication, data processing, control and optimization. Many CPSs are controlled and monitored by real-time control systems that use communication networks to transmit and receive data from systems modeled by physical processes. Existing studies have addressed a breadth of challenges related to the design of CPSs. However, there is a lack of studies on uncertain CPSs subject to dynamic unknown inputs and cyber-attacks---an artifact of the insertion of communication networks and the growing complexity of CPSs. The objective of this dissertation is to create secure, computational foundations for uncertain CPSs by establishing a framework to control, estimate and optimize the operation of these systems. With major emphasis on power networks, the dissertation deals with the design of secure computational methods for uncertain CPSs, focusing on three crucial issues---(1) cyber-security and risk-mitigation, (2) network-induced time-delays and perturbations and (3) the encompassed extreme time-scales. The dissertation consists of four parts. In the first part, we investigate dynamic state estimation (DSE) methods and rigorously examine the strengths and weaknesses of the proposed routines under dynamic attack-vectors and unknown inputs. In the second part, and utilizing high-frequency measurements in smart grids and the developed DSE methods in the first part, we present a risk mitigation strategy that minimizes the encountered threat levels, while ensuring the continual observability of the system through available, safe measurements. The developed methods in the first two parts rely on the assumption that the uncertain CPS is not experiencing time-delays, an assumption that might fail under certain conditions. To overcome this challenge, networked unknown input

  16. Improved Skin Penetration Using In Situ Nanoparticulate Diclofenac Diethylamine in Hydrogel Systems: In Vitro and In Vivo Studies.

    Science.gov (United States)

    Sengupta, Soma; Banerjee, Sarita; Sinha, Biswadip; Mukherjee, Biswajit

    2016-04-01

    Delivering diclofenac diethylamine transdermally by means of a hydrogel is an approach to reduce or avoid systemic toxicity of the drug while providing local action for a prolonged period. In the present investigation, a process was developed to produce nanosize particles (about 10 nm) of diclofenac diethylamine in situ during the development of hydrogel, using simple mixing technique. Hydrogel was developed with polyvinyl alcohol (PVA) (5.8% w/w) and carbopol 71G (1.5% w/w). The formulations were evaluated on the basis of field emission scanning electron microscopy, texture analysis, and the assessment of various physiochemical properties. Viscosity (163-165 cps for hydrogel containing microsize drug particles and 171-173 cps for hydrogel containing nanosize drug particles, respectively) and swelling index (varied between 0.62 and 0.68) data favor the hydrogels for satisfactory topical applications. The measured hardness of the different hydrogels was uniform indicating a uniform spreadability. Data of in vitro skin (cadaver) permeation for 10 h showed that the enhancement ratios of the flux of the formulation containing nanosize drug (without the permeation enhancer) were 9.72 and 1.30 compared to the formulation containing microsized drug and the marketed formulations, respectively. In vivo plasma level of the drug increased predominantly for the hydrogel containing nanosize drug-clusters. The study depicts a simple technique for preparing hydrogel containing nanosize diclofenac diethylamine particles in situ, which can be commercially viable. The study also shows the advantage of the experimental transdermal hydrogel with nanosize drug particles over the hydrogel with microsize drug particles.

  17. Spatio-temporal patterns of energy consumption-related GHG emissions in China's crop production systems

    International Nuclear Information System (INIS)

    Zhen, Wei; Qin, Quande; Wei, Yi-Ming

    2017-01-01

    This paper aims to reveal the spatio-temporal patterns of energy consumption-related greenhouse gas (ECR-GHG) emissions in China's crop production systems (CPSs). The relevant crop production data from 31 provinces during 1997–2014 are utilized. In order to fully reflect the energy consumption and ECR-GHG emissions in CPSs, energy balance techniques are adopted from a consumption perspective. The driving factors behind ECR-GHG emissions are identified by means of a Logarithmic Mean Divisia Index analysis at both national and provincial levels. The results are as follows: (1) The yield of China's CPS is not positively correlated with energy consumption, and China's CPS has the relatively high potential to conserve energy and reduce ECR-GHG emissions; (2) Most of China's provinces have experienced enormous growth in ECR-GHG emissions; however there are relatively significant regional disparities; (3) ECR-GHG emissions from CPSs were mostly derived directly from the consumption of chemical fertilizers and diesel oil; (4) Areal productivity is the determining factor in the growth of ECR-GHG emissions, whereas the emission coefficient and energy mix are the main inhibiting factors; (5) Energy intensity has not achieved its full potential to decrease ECR-GHG emissions. This study provides insights into the potential for sustainable crop production in China. - Highlights: • We analyzed the spacial and temporal features of ECR-GHG emissions from CPSs. • We quantified the driving forces of ECR-GHG emissions from CPSs. • ECR-GHG emissions from CPSs are estimated from a consumption perspective. • Regional disparities exist in the level of ECR-GHG emissions from China's CPSs. • Optimizing chemical fertilizer consumption structure is urgent to reduce ECR-GHG.

  18. Design and Characterization of Microemulsion Systems for Naproxen

    Directory of Open Access Journals (Sweden)

    Soroosh Eftekhari

    2013-02-01

    Full Text Available Purpose: This research was aimed to formulate and characterize a microemolsion systems as a topical delivery system of naproxen for relief of symptoms of rheumatoid arthritis, osteoarthritis and treatment of dysmenorrheal. Methods: ME formulations prepared by mixing of appropriate amount of surfactant including Tween 80 and Span80, co-surfactant such as propylene glycol (PG and oil phase including Labrafac PG –transcutol P (10:1 ratio. The prepared microemolsions were evaluated regarding their particle size, zeta potential, conductivity, stability, viscosity, differential scanningcalorimetry (DSC, scanning electron microscopy (SEM, refractory index (RI and pH. Results: The mean droplets size of microemulsion formulation were in the range of 7.03 to 79.8 nm, and its refractory index (RI and pH were 1.45 and 6.75, respectively. Viscosity range was 253.73- 802.63cps. Drug release profile showed that 26.15% of thedrug released in the first 24 hours of experiment. Also, Hexagonal and bicontinuous structures were seen in the SEM photograph of the microemulsions. Conclusion: characterization, physicochemical properties and in vitro release were dependent upon the contents of S/C ratio, water and, oil phase percentage in formulations. Also, ME-6 may be preferable for topical naproxen formulation.

  19. Autonomous perception and decision making in cyber-physical systems

    Science.gov (United States)

    Sarkar, Soumik

    2011-07-01

    The cyber-physical system (CPS) is a relatively new interdisciplinary technology area that includes the general class of embedded and hybrid systems. CPSs require integration of computation and physical processes that involves the aspects of physical quantities such as time, energy and space during information processing and control. The physical space is the source of information and the cyber space makes use of the generated information to make decisions. This dissertation proposes an overall architecture of autonomous perception-based decision & control of complex cyber-physical systems. Perception involves the recently developed framework of Symbolic Dynamic Filtering for abstraction of physical world in the cyber space. For example, under this framework, sensor observations from a physical entity are discretized temporally and spatially to generate blocks of symbols, also called words that form a language. A grammar of a language is the set of rules that determine the relationships among words to build sentences. Subsequently, a physical system is conjectured to be a linguistic source that is capable of generating a specific language. The proposed technology is validated on various (experimental and simulated) case studies that include health monitoring of aircraft gas turbine engines, detection and estimation of fatigue damage in polycrystalline alloys, and parameter identification. Control of complex cyber-physical systems involve distributed sensing, computation, control as well as complexity analysis. A novel statistical mechanics-inspired complexity analysis approach is proposed in this dissertation. In such a scenario of networked physical systems, the distribution of physical entities determines the underlying network topology and the interaction among the entities forms the abstract cyber space. It is envisioned that the general contributions, made in this dissertation, will be useful for potential application areas such as smart power grids and

  20. Aseismic foundation system for nuclear power stations

    International Nuclear Information System (INIS)

    Jolivet, F.; Richli, M.

    1977-01-01

    The aseismic foundation system, as described in this paper, is a new development, which makes it possible to build standard nuclear power stations in areas exposed to strong earthquakes. The principle consists in interposing a device between the buildings of the nuclear island and the foundation soil which limits the value of the horizontal acceleration in the nuclear island buildings. The nuclear island foundations consists of a double raft with aseismic bearings interposed between the upper and lower raft. These bearings are placed on top of short concrete pedestals constructed on the lower raft. The space thus provided between the two rafts allows access to the bearings. The bearing consists of two parts: a block of reinforced elastomer, a set of friction plates such as stainless steel+bronze with lead. The reinforced neoprene pad acts as a soft horizontal spring imparting a first mode of translation to the structure with the frequency of about 1 c.p.s. depending only on the characteristics of the bearing. As this first mode is predominant, the value of horizontal accelerations at each level for all buildings are almost identical. The above mentioned frequency has been selected in order to be outside the range of natural frequencies of the buildings themselves and of the frequency of the equipment. The friction plates due to their nature and surface treatment permit to ensure a consistent value of the coefficient of friction 'f' so as to limit the maximum horizontal earthquake forces to values close to fxg. Under a low level earthquake (0.15 g-0.20 g) the structure vibrates and returns to its original position. The temporary relative displacement during such an earthquake can reach about 0.10 m. Under an earthquake of higher level (up to 0.60 g) the vibrating structure slides on the friction plates. The complete detailed design together with experimental evidence have shown that the system is operational