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Sample records for swift follow-up observations

  1. INTEGRAL and Swift follow-up observations of XMMSL1 J171900.4- 353217

    DEFF Research Database (Denmark)

    Pavan, L.; Terrier, R.; Bozzo, E.

    2010-01-01

    Following the detection of hard X-ray emission from XMMSL1 J171900.4-353217 (Atel #2607) with INTEGRAL (Atel #2803), a Swift/XRT follow-up observation (2 ks) was performed on 2010 August 20 from 13:03 to 14:53, simultaneously with the newly INTEGRAL observation of the same FOV (2010 August 19 at ...

  2. Afterglow Population Studies from Swift Follow-Up Observations of Fermi LAT GRBs

    Science.gov (United States)

    Racusin, Judith L.; Oates, S. R.; McEnery, J.; Vasileiou, V.; Troja, E.; Gehrels, N.

    2010-01-01

    The small population of Fermi LAT detected GRBs discovered over the last year has been providing interesting and unexpected clues into GRB prompt and afterglow emission mechanisms. Over the last 5 years, it has been Swift that has provided the robust data set of UV/optical and X-ray afterglow observations that opened many windows into other components of GRB emission structure. We explore the new ability to utilize both of these observatories to study the same GRBs over 10 orders of magnitude in energy, although not always concurrently. Almost all LAT GRBs that have been followed-up by Swift within 1-day have been clearly detected and carefully observed. We will present the context of the lower-energy afterglows of this special subset of GRBs that has > 100 MeV emission compared to the hundreds in the Swift database that may or may not have been observed by LAT, and theorize upon the relationship between these properties and the origin of the high energy gamma-ray emission.

  3. XMM FOLLOW-UP OBSERVATIONS OF THREE SWIFT BAT-SELECTED ACTIVE GALACTIC NUCLEI

    International Nuclear Information System (INIS)

    Trippe, M. L.; Reynolds, C. S.; Koss, M.; Mushotzky, R. F.; Winter, L. M.

    2011-01-01

    We present XMM-Newton observations of three active galactic nuclei (AGNs) taken as part of a hunt to find very heavily obscured Compton-thick AGNs. For obscuring columns greater than 10 25 cm -2 , AGNs are only visible at energies below 10 keV via reflected/scattered radiation, characterized by a flat power law. We therefore selected three objects (ESO 417-G006, IRAS 05218-1212, and MCG -01-05-047) from the Swift Burst Alert Telescope (BAT) hard X-ray survey catalog with Swift X-ray Telescope (XRT) 0.5-10 keV spectra with flat power-law indices as candidate Compton-thick sources for follow-up observations with the more sensitive instruments on XMM-Newton. The XMM spectra, however, rule out reflection-dominated models based on the weakness of the observed Fe Kα lines. Instead, the spectra are well fit by a model of a power-law continuum obscured by a Compton-thin absorber plus a soft excess. This result is consistent with previous follow-up observations of two other flat-spectrum BAT-detected AGNs. Thus, out of the six AGNs in the 22 month BAT catalog with apparently flat Swift XRT spectra, all five that have had follow-up observations are not likely Compton thick. We also present new optical spectra of two of these objects, IRAS 05218-1212 and MCG -01-05-047. Interestingly, though both the AGNs have similar X-ray spectra, their optical spectra are completely different, adding evidence against the simplest form of the geometric unified model of AGNs. IRAS 05218-1212 appears in the optical as a Seyfert 1, despite the ∼8.5 x 10 22 cm -2 line-of-sight absorbing column indicated by its X-ray spectrum. MCG -01-05-047's optical spectrum shows no sign of AGN activity; it appears as a normal galaxy.

  4. Chandra and NuSTAR Follow-up Observations of Swift-BAT-selected AGNs

    Science.gov (United States)

    Marchesi, S.; Tremblay, L.; Ajello, M.; Marcotulli, L.; Paggi, A.; Cusumano, G.; La Parola, V.; Segreto, A.

    2017-10-01

    Based on current models of the cosmic X-ray background (CXB), heavily obscured active galactic nuclei (AGNs) are expected to make up ˜10% of the peak emission of the CXB and ˜20% of the total population of AGNs, yet few of these sources have been recorded and characterized in current surveys. Here we present the Chandra follow-up observation of 14 AGNs detected by Swift-BAT. For five sources in the sample, NuSTAR observations in the 3-80 keV band are also available. The X-ray spectral fitting over the 0.3-150 keV energy range allows us to determine the main X-ray spectral parameters, such as the photon index and the intrinsic absorption, of these objects and to make hypotheses on the physical structures responsible for the observed spectra. We find that 13 of the 14 objects are absorbed AGNs, and one is a candidate Compton-thick AGN, having intrinsic absorption {N}{{H}}> {10}24 cm-2. Finally, we verified that the use of NuSTAR observations is strategic to strongly constrain the properties of obscured AGNs, since the best-fit values we obtained for parameters such as the power-law photon index Γ and the intrinsic absorption {N}{{H}} changed sometimes significantly fitting the spectra with and without the use of NuSTAR data.

  5. The Kepler follow-up observation program

    DEFF Research Database (Denmark)

    Gautier...[], T.N.; Batalha, N.M.; Borucki, W. J.

    2010-01-01

    The Kepler Mission was launched on March 6, 2009 to perform a photometric survey of more than 100,000 dwarf stars to search for terrestrial-size planets with the transit technique. Follow-up observations of planetary candidates identified by detection of transit-like events are needed both...... for identification of astrophysical phenomena that mimic planetary transits and for characterization of the true planets and planetary systems found by Kepler. We have developed techniques and protocols for detection of false planetary transits and are currently conducting observations on 177 Kepler targets...

  6. Swift follow-up of the newly discovered burster millisecond pulsar IGR J17511-3057

    DEFF Research Database (Denmark)

    Bozzo, E.; Ferrigno, C.; Kuulkers, E.

    2009-01-01

    Following the discovery of the new hard X-ray transient IGR J17511-3057 by INTEGRAL (Atel #2196) and its classification as a millisecond pulsar by RXTE (Atel #2197), a Swift ToO was performed. Swift/XRT observed IGR J17511-3057 on 2009-09-13 at 19:53:31 for a total exposure time of 4 ks. The firs...

  7. Goddard Robotic Telescope - Optical Follow-up of GRBs and Coordinated Observations of AGNs

    Science.gov (United States)

    Sakamoto, T.; Wallace, C. A.; Donato, D.; Gehrels, N.; Okajima, T.; Ukwatta, T. N.

    2010-01-01

    Since it is not possible to predict when a Gamma-Ray Burst (GRB) will occur or when Active Galactic Nucleus (AGN) flaring activity starts, follow-up/monitoring ground telescopes must be located as uniformly as possible all over the world in order to collect data simultaneously with Fermi and Swift detections. However, there is a distinct gap in follow-up coverage of telescopes in the eastern U.S. region based on the operations of Swift. Motivated by this fact, we have constructed a 14" fully automated optical robotic telescope, Goddard Robotic Telescope (GRT), at the Goddard Geophysical and Astronomical Observatory. The aims of our robotic telescope are 1) to follow-up Swift/Fermi GRBs and 2) to perform the coordinated optical observations of Fermi Large Area Telescope (LAT) AGN. Our telescope system consists of off-the-shelf hardware. With the focal reducer, we are able to match the field of view of Swift narrow instruments (20' x 20'). We started scientific observations in mid-November 2008 and GRT has been fully remotely operated since August 2009. The 3(sigma) upper limit in a 30-second exposure in the R filter is approx.15.4 mag; however, we can reach to approx.18 mag in a 600-second exposures. Due to the weather condition at the telescope site. our observing efficiency is 30-40%, on average.

  8. MASTER Prompt and Follow-Up GRB Observations

    Directory of Open Access Journals (Sweden)

    Nataly Tyurina

    2010-01-01

    Full Text Available We presented the results of last years GRB observations obtained on the MASTER robotic telescope, which is the only telescope of its kind in Russia. These results include 5 prompt observations of GRB in 2008 and 2009, follow-up observations of 15 other GRBs in 2008-2009, the first observations in different polarization angles of optical emission from the gamma-ray bursts GRB091020, and observations in different polarization angles for GRB091127 and GRB090820.

  9. Swift follow-up of gravitational wave triggers: results from the first aLIGO run and optimization for the future

    Science.gov (United States)

    Evans, P. A.; Kennea, J. A.; Palmer, D. M.; Bilicki, M.; Osborne, J. P.; O'Brien, P. T.; Tanvir, N. R.; Lien, A. Y.; Barthelmy, S. D.; Burrows, D. N.; Campana, S.; Cenko, S. B.; D'Elia, V.; Gehrels, N.; Marshall, F. E.; Page, K. L.; Perri, M.; Sbarufatti, B.; Siegel, M. H.; Tagliaferri, G.; Troja, E.

    2016-10-01

    During its first observing run, in late 2015, the advanced Laser Interferometer Gravitational-wave Observatory facility announced three gravitational wave (GW) triggers to electromagnetic follow-up partners. Two of these have since been confirmed as being of astrophysical origin: both are binary black hole mergers at ˜ 500 Mpc; the other trigger was later found not to be astrophysical. In this paper, we report on the Swift follow-up observations of the second and third triggers, including details of 21 X-ray sources detected; none of which can be associated with the GW event. We also consider the challenges that the next GW observing run will bring as the sensitivity and hence typical distance of GW events will increase. We discuss how to effectively use galaxy catalogues to prioritize areas for follow-up, especially in the presence of distance estimates from the GW data. We also consider two galaxy catalogues and suggest that the high completeness at larger distances of the 2MASS Photometric Redshift catalogue makes it very well suited to optimize Swift follow-up observations.

  10. Radio follow-up observations of stellar tidal disruption flares: Constraints on off-axis jets

    Directory of Open Access Journals (Sweden)

    Körding E.

    2012-12-01

    Full Text Available Observations of active galactic nuclei (AGN and X-ray binaries have shown that relativistic jets are ubiquitous when compact objects accrete. One could therefore anticipate the launch of a jet after a star is disrupted and accreted by a massive black hole. This birth of a relativistic jet may have been observed recently in two stellar tidal disruption flares (TDFs, which were discovered in gamma-rays by Swift. Yet no transient radio emission has been detected from the tens of TDF candidates that were discovered at optical to soft X-ray frequencies. Because the sample that was followed-up at radio frequencies is small, the non-detections can be explained by Doppler boosting, which reduces the jet flux for off-axis observers. Plus, the existing followup observation are mostly within ∼ 10 months of the discovery, so the non-detections can also be due to a delay of the radio emission with respect to the time of disruption. To test the conjecture that all TDFs launch jets, we obtained 5 GHz follow-up observations with the Jansky VLA of six known TDFs. To avoid missing delayed jet emission, our observations probe 1–8 years since the estimated time of disruption. None of the sources are detected, with very deep upper limits at the 10 micro Jansky level. These observations rule out the hypothesis that these TDFs launched jets similar to radio-loud quasars. We also constrain the possibility that the flares hosted a jet identical to Sw 1644+57.

  11. IceCube-171106A: Swift observations

    Science.gov (United States)

    Keivani, A.; Fox, D. B.; DeLaunay, J. J.; Kennea, J. A.; Evans, P. A.; Cowen, D. F.; Osborne, J. P.; Marshall, F. E.; Swift-IceCube Collaboration

    2017-11-01

    Swift has observed the field of IceCube-171106A (Rev 0; subsequently updated to Rev 1, GCN #22105), utilizing the on-board 19-point tiling pattern to cover a region centered on RA,Dec (J2000) = (340.0d,+7.4d), with a radius of 0.8 & deg;.

  12. Loss to follow-up in an international, multicentre observational study

    DEFF Research Database (Denmark)

    Mocroft, A; Kirk, O; Aldins, P

    2008-01-01

    OBJECTIVE: The aim of this work was to assess loss to follow-up (LTFU) in EuroSIDA, an international multicentre observational cohort study. METHODS: LTFU was defined as no follow-up visit, CD4 cell count measurement or viral load measurement after 1 January 2006. Poisson regression was used...

  13. SWIFT J1749.4-2807 : X-ray decay, refined position and optical observation

    NARCIS (Netherlands)

    Yang, Y.J.; Russell, D. M.; Wijnands, R.; van der Klis, M.; Altamirano, D.; Patruno, A.; Watts, A.; Armas Padilla, M.; Cavecchi, Y.; Degenaar, N.; Kalamkar, M.; Kaur, R.; Linares, M.; Casella, P.; Rea, N.; Soleri, P.; Lewis, F.; Kong, A. K. H.

    We analyzed seven, target ID 31686, Swift follow-up observations of the neutron-star X-ray transient Swfit J1749.4-2807 (Wijnands et al. 2009) currently in outburst and which was found to be an accreting millisecond X-ray pulsar (ATel #2565). The observations span from April 11 to April 20.

  14. Chandra and Swift Observations of Unidentified Fermi-LAT Objects

    Science.gov (United States)

    Donato, Davide; Cheung, T.; Gehrels, N.

    2010-03-01

    In the last year we targeted some of the unidentified Fermi-LAT objects (UFOs) at high Galactic latitude with Chandra and Swift in order to determine the basic properties (positions, fluxes, hardness ratios) of all X-ray sources within the Fermi-LAT localization circles. These satellites enable us to detect the X-ray conterparts with a flux limit that is at least an order of magnitude lower than achieved in extant RASS data and to further follow-up at other wavelengths, with the ultimate goal to reveal the nature of these enigmatic gamma-ray sources. Here we present the results obtained with 5 Chandra pointings of high Galactic latitude UFOs in the Fermi-LAT 3-months bright source list. The association of detected X-ray sources within the improved 11-months Fermi-LAT localization circles with available optical and radio observations is discussed.

  15. Swift observations of GS 1826-238

    Science.gov (United States)

    Ji, L.; Santangelo, A.; Zhang, S.; Ducci, L.; Suleimanov, V.

    2018-02-01

    GS 1826-238 is a well-studied low-mass X-ray binary neutron star. This source was in a persistent hard state since its discovery in 1988 and until 2014 June. After that, the source exhibited several softer periods of enhanced intensity in the energy range 2-20 keV. We studied the long-term light curves of MAXI (Monitor of All Sky X-ray Image) and Swift/BAT, and found clearly two branches in the MAXI-BAT and hardness-intensity diagrams, which correspond to the persistent state and softer periods, respectively. We analysed 21 Swift/XRT observations, of which four were located in the persistent state while the others were in softer periods or in a state between them. The XRT spectra could be generally fitted by using an absorbed Comptonization model with no other components required. We found a peculiar relationship between the luminosity and the hardness in the energy range of 0.6-10 keV: when the luminosity is larger (smaller) than 4 per cent-6 per cent Ledd, the hardness is anti-correlated (correlated) with luminosity. We also estimated the variability for each observation by using the fractional rms in the 0.1-10 Hz range. We found that the observations in the persistent state had a large fractional rms of ˜25 per cent, similar to other low-mass X-ray binaries. However, the variability is mainly found in the range of 5 per cent-20 per cent during softer periods. We suggest that GS 1826-238 did not evolve into the soft state of atoll sources, and all the observed XRT observations during the softer periods resemble a peculiar intermediate state of atoll sources.

  16. GCN CIRCULAR 21672, LIGO/Virgo G298048: INTEGRAL pointed follow-up observations

    DEFF Research Database (Denmark)

    Savchenko, V.; Ferrigno, C.; Kuulkers, E.

    2017-01-01

    INTEGRAL is an observatory with multiple instruments: a gamma-ray spectrometer (20 keV - 8 MeV, SPI), an imager (15 keV - 2 MeV, IBIS),an X-ray monitor (3 - 25 keV, JEM-X), and an optical monitor (V band,OMC). Our group requested and obtained follow-up observations of the LIGO/Virgo candidate NS...

  17. An Observational Study with Long-Term Follow-Up of Canine Cognitive Dysfunction

    DEFF Research Database (Denmark)

    Fast, R.; Schutt, T.; Toft, N.

    2013-01-01

    = .99). Conclusions and Clinical Importance: A few key questions addressing sleep-wake cycle, interaction, and signs of confusion and anxiety can be used as a clinical marker of CCD. Special attention should be paid to anxiety in dogs with CCD because it may be especially stressful to both dog and owner......Background: Canine cognitive dysfunction (CCD) is a neurodegenerative condition affecting geriatric dogs and sharing several characteristics with human Alzheimer's disease (AD). CCD manifests as alterations of behavioral patterns and daily routines. Clinical signs are associated...... questionnaire and allocated to CCD, borderline CCD (b-CCD) and non-CCD groups. The dogs were included in 2008-2009 and followed up in an observational study until follow-up in 2012. Results: Four key clinical signs dominated in dogs with CCD: sleeping during the day and restless at night, decreased interaction...

  18. VERITAS follow-up observations of IceCube neutrino event 170922A

    Science.gov (United States)

    Mukherjee, Reshmi

    2017-10-01

    The VERITAS gamma-ray telescope array was used to perform follow-up observations of the high-energy neutrino event detected by the IceCube collaboration on September 22nd, 2017 20:54:30 UTC (GCN Circular #21916). & nbsp; & nbsp; VERITAS observed the location around the initial position reported by IceCube in the GCN/AMON Notice dated Fri 22 Sep 17 20:55:13 UTC (RA = 77.29 deg, Dec = 5.75 deg in J2000 coordinates) under partial cloud coverage for one hour.

  19. THE DETECTION OF A SN IIn IN OPTICAL FOLLOW-UP OBSERVATIONS OF ICECUBE NEUTRINO EVENTS

    Energy Technology Data Exchange (ETDEWEB)

    Aartsen, M. G.; Abraham, K.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Altmann, D.; Anderson, T.; Archinger, M.; Arguelles, C.; Arlen, T. C.; Auffenberg, J.; Bai, X.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Becker Tjus, J.; Becker, K.-H. [Astrophysics Research Centre, School of Mathematics and Physics, Queen' s University Belfast, Belfast, BT7 1NN (United Kingdom); Collaboration: IceCube Collaboration; for the PTF Collaboration; for the Swift Collaboration; for the Pan-STARRS1 Science Consortium; and others

    2015-09-20

    The IceCube neutrino observatory pursues a follow-up program selecting interesting neutrino events in real-time and issuing alerts for electromagnetic follow-up observations. In 2012 March, the most significant neutrino alert during the first three years of operation was issued by IceCube. In the follow-up observations performed by the Palomar Transient Factory (PTF), a Type IIn supernova (SN IIn) PTF12csy was found 0.°2 away from the neutrino alert direction, with an error radius of 0.°54. It has a redshift of z = 0.0684, corresponding to a luminosity distance of about 300 Mpc and the Pan-STARRS1 survey shows that its explosion time was at least 158 days (in host galaxy rest frame) before the neutrino alert, so that a causal connection is unlikely. The a posteriori significance of the chance detection of both the neutrinos and the SN at any epoch is 2.2σ within IceCube's 2011/12 data acquisition season. Also, a complementary neutrino analysis reveals no long-term signal over the course of one year. Therefore, we consider the SN detection coincidental and the neutrinos uncorrelated to the SN. However, the SN is unusual and interesting by itself: it is luminous and energetic, bearing strong resemblance to the SN IIn 2010jl, and shows signs of interaction of the SN ejecta with a dense circumstellar medium. High-energy neutrino emission is expected in models of diffusive shock acceleration, but at a low, non-detectable level for this specific SN. In this paper, we describe the SN PTF12csy and present both the neutrino and electromagnetic data, as well as their analysis.

  20. Moyamoya disease accompanied by brain aneurysm follow-up observation by CT

    International Nuclear Information System (INIS)

    Yoshihara, Takashi; Kitaoka, Tamotsu; Nomura, Masayuki

    1982-01-01

    To date 30 cases of Moyamoya disease complicated with brain aneurysm have been reported in the literature. We experienced a case of Moyamoya disease who after developing ventricular hemorrhage received cerebral angiography which revealed aneurysm at the periphery of the Moyamoya vessels. This case is reported with a review of the literature. The case is a 31 year old male who devolped headache and vomiting while at work. CT revealed ventricular hemorrhage and cerebral angiography disclosed obstruction of the bilateral internal carotid artery and Moyamoya vessels at the base of the brain. At the periphery of the Moyamoya vessels, brain aneurysm 3 x 3 mm in size was observed. This aneurysm was followed by contrast enhanced CT, and CT on the 50th day after development of the symptoms suggested disappearance of the aneurysm. It can be said that CT is an effective procedure for the follow-up observation of aneurysm of this type. (author)

  1. Swift Observations of GAIA17dev and GAIA17dez

    Science.gov (United States)

    Grupe, Dirk; Schartel, Norbert; Komossa, S.

    2018-01-01

    We report of Swift observations of the Active Galactic Nuclei GAIA 17dev and GAIA 17dez which were detected by GAIA in an optically bright state (A. Delgado et al. TNS AT report 15273 and 15277, respectively).

  2. Follow Up of GW170817 and Its Electromagnetic Counterpart by Australian-Led Observing Programmes

    Science.gov (United States)

    Andreoni, I.; Ackley, K.; Cooke, J.; Acharyya, A.; Allison, J. R.; Anderson, G. E.; Ashley, M. C. B.; Baade, D.; Bailes, M.; Bannister, K.; Beardsley, A.; Bessell, M. S.; Bian, F.; Bland, P. A.; Boer, M.; Booler, T.; Brandeker, A.; Brown, I. S.; Buckley, D. A. H.; Chang, S.-W.; Coward, D. M.; Crawford, S.; Crisp, H.; Crosse, B.; Cucchiara, A.; Cupák, M.; de Gois, J. S.; Deller, A.; Devillepoix, H. A. R.; Dobie, D.; Elmer, E.; Emrich, D.; Farah, W.; Farrell, T. J.; Franzen, T.; Gaensler, B. M.; Galloway, D. K.; Gendre, B.; Giblin, T.; Goobar, A.; Green, J.; Hancock, P. J.; Hartig, B. A. D.; Howell, E. J.; Horsley, L.; Hotan, A.; Howie, R. M.; Hu, L.; Hu, Y.; James, C. W.; Johnston, S.; Johnston-Hollitt, M.; Kaplan, D. L.; Kasliwal, M.; Keane, E. F.; Kenney, D.; Klotz, A.; Lau, R.; Laugier, R.; Lenc, E.; Li, X.; Liang, E.; Lidman, C.; Luvaul, L. C.; Lynch, C.; Ma, B.; Macpherson, D.; Mao, J.; McClelland, D. E.; McCully, C.; Möller, A.; Morales, M. F.; Morris, D.; Murphy, T.; Noysena, K.; Onken, C. A.; Orange, N. B.; Osłowski, S.; Pallot, D.; Paxman, J.; Potter, S. B.; Pritchard, T.; Raja, W.; Ridden-Harper, R.; Romero-Colmenero, E.; Sadler, E. M.; Sansom, E. K.; Scalzo, R. A.; Schmidt, B. P.; Scott, S. M.; Seghouani, N.; Shang, Z.; Shannon, R. M.; Shao, L.; Shara, M. M.; Sharp, R.; Sokolowski, M.; Sollerman, J.; Staff, J.; Steele, K.; Sun, T.; Suntzeff, N. B.; Tao, C.; Tingay, S.; Towner, M. C.; Thierry, P.; Trott, C.; Tucker, B. E.; Väisänen, P.; Krishnan, V. Venkatraman; Walker, M.; Wang, L.; Wang, X.; Wayth, R.; Whiting, M.; Williams, A.; Williams, T.; Wolf, C.; Wu, C.; Wu, X.; Yang, J.; Yuan, X.; Zhang, H.; Zhou, J.; Zovaro, H.

    2017-12-01

    The discovery of the first electromagnetic counterpart to a gravitational wave signal has generated follow-up observations by over 50 facilities world-wide, ushering in the new era of multi-messenger astronomy. In this paper, we present follow-up observations of the gravitational wave event GW170817 and its electromagnetic counterpart SSS17a/DLT17ck (IAU label AT2017gfo) by 14 Australian telescopes and partner observatories as part of Australian-based and Australian-led research programs. We report early- to late-time multi-wavelength observations, including optical imaging and spectroscopy, mid-infrared imaging, radio imaging, and searches for fast radio bursts. Our optical spectra reveal that the transient source emission cooled from approximately 6 400 K to 2 100 K over a 7-d period and produced no significant optical emission lines. The spectral profiles, cooling rate, and photometric light curves are consistent with the expected outburst and subsequent processes of a binary neutron star merger. Star formation in the host galaxy probably ceased at least a Gyr ago, although there is evidence for a galaxy merger. Binary pulsars with short (100 Myr) decay times are therefore unlikely progenitors, but pulsars like PSR B1534+12 with its 2.7 Gyr coalescence time could produce such a merger. The displacement ( 2.2 kpc) of the binary star system from the centre of the main galaxy is not unusual for stars in the host galaxy or stars originating in the merging galaxy, and therefore any constraints on the kick velocity imparted to the progenitor are poor.

  3. Follow-up observations for the Asteroid Catalog using AKARI Spectroscopic Observations

    Science.gov (United States)

    Hasegawa, Sunao; Kuroda, Daisuke; Yanagisawa, Kenshi; Usui, Fumihiko

    2017-12-01

    In the 1-2.5 μm range, spectroscopic observations are made on the AcuA-spec asteroids, the spectra of which were obtained in a continuous covered mode between 2.5-5.0 μm by AKARI. Based on the Bus-DeMeo taxonomy (DeMeo et al. 2009, Icarus, 202, 160), all the AcuA-spec asteroids are classified, using both published and our observational data. Additionally, taking advantage of the Bus-DeMeo taxonomy characteristics, we constrain the characteristic of each spectral type by combining the taxonomy results with the other physical observational data from colorimetry, polarimetry, radar, and radiometry. As a result, it is suggested that certain C-, Cb-, B-type, dark X-, and D-complex asteroids have spectral properties compatible with those of anhydrous interplanetary dust particles with tiny bright material, such as water ice. This supports the proposal regarding the C-complex asteroids (Vernazza et al. 2015, ApJ, 806, 204; 2017, AJ, 153, 72). A combination of the Bus-DeMeo taxonomy for AcuA-spec asteroids with other physical clues, such as the polarimetric inversion angle, radar albedo, and mid-infrared spectroscopic spectra, will be beneficial for surface material constraints from the AcuA-spec asteroid observations.

  4. VizieR Online Data Catalog: 27 pulsating DA WDs follow-up observations (Hermes+, 2017)

    Science.gov (United States)

    Hermes, J. J.; Gansicke, B. T.; Kawaler, S. D.; Greiss, S.; Tremblay, P.-E.; Gentile Fusillo, N. P.; Raddi, R.; Fanale, S. M.; Bell, K. J.; Dennihy, E.; Fuchs, J. T.; Dunlap, B. H.; Clemens, J. C.; Montgomery, M. H.; Winget, D. E.; Chote, P.; Marsh, T. R.; Redfield, S.

    2017-11-01

    All observations analyzed here were collected by the Kepler spacecraft with short-cadence exposures from 2012 to 2016. Full details of the raw and processed Kepler and K2 observations are summarized in Table2. We complemented our space-based photometry of these 27 pulsating hydrogen-atmosphere white dwarfs (DAVs) by determining their atmospheric parameters based on model-atmosphere fits to follow-up spectroscopy obtained from two 4m class, ground-based facilities. Spectra taken with the 4.2m William Herschel Telescope (WHT) on the island of La Palma cover roughly 3800-5100Å at roughly 2.0Å resolution; spanning 2013 Jun 06 to 2014 Jul 25. Spectra taken with the 4.1m Southern Astrophysical Research (SOAR) telescope on Cerro Pachon in Chile cover roughly 3600-5200Å; spanning 2014 Oct 13 to 2017 Apr 21. We detail these spectroscopic observations and their resultant fits in Table 3. (4 data files).

  5. Radio follow-up observations of GW170608 with the Jansky VLA

    Science.gov (United States)

    Artkop, Kyle; Smith, Rachel; Corsi, Alessandra

    2018-01-01

    After the identification of a high-energy transient potentially related to the binary black hole merger GW150914 by the Fermi satellite, the question of whether binary black holes can be associated to electromagnetic counterparts remains highly debated. Here we present radio follow-up observations of GW170608, a binary black hole merger occurred during the second observing run (O2) of the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO). Our search focuses on a specific field in which a high-energy transient was detected by the Fermi/LAT, and makes use of data collected at 1.4 GHZ with the Karl G. Jansky Very Large Array. Our results show evidence for the presence of a few previously uncataloged radio sources in the field, likely unrelated to the gravitational wave event. We describe their properties, and provide an interpretation for the origin of their radio emission (AGN versus star formation). Finally, we put our findings in the context of future searches for electromagnetic counterparts to binary black hole mergers.

  6. Changes observed in diabetic retinopathy: eight-year follow-up of a Spanish population.

    Science.gov (United States)

    Romero-Aroca, Pedro; de la Riva-Fernandez, Sofia; Valls-Mateu, Aida; Sagarra-Alamo, Ramon; Moreno-Ribas, Antonio; Soler, Nuria

    2016-10-01

    To determine the changes in the incidence of diabetic retinopathy (DR), diabetic macular oedema (DMO) and their risk factors in a population-based study of patients with diabetes mellitus (DM) referred to our 16 Primary Health Care Areas (HCAs). Prospective population-based study of a total of 15 396 Caucasian patients with DM, who represent 86.53% of the total patients with DM in our HCAs, were studied over an 8-year follow-up period. All patients were screened with a mean follow-up of 3.18±1.11 times for each patient over the 8 years. The yearly mean value of any DR was 8.37±2.19% (8.09%-8.99%); of advanced DR yearly mean value of 0.46±0.22% (0.03-0.78); and of DMO a yearly mean value of 2.19±0.18% (2%-2.49%). A clear increase was observed in the last 3 years, any DR increased from 8.09% in 2007 to 8.99% in 2014, and DMO from 2% in 2007 to 2.49% in 2014. These increases were more evident in some age groups. For patients with any DR aged 41-50 and 51-60 and for patients with advanced DR aged 41-50, 51-60 and 61-70, the increase was more marked, related to an increase in HbA1c values or to patients treated with insulin. An increase in the incidence of DR and DMO was observed, especially in the younger patients aged between 31 and 70 years. This is linked to bad metabolic control of DM. Our results suggest a greater number of ocular complications in the near future, such as neovascular glaucoma, if these current findings are not addressed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  7. Prompt Emission Observations of Swift BAT Bursts

    Science.gov (United States)

    Barthelmy, Scott

    2009-01-01

    We review the prompt emission properties of Swift BAT gamma-ray bursts (GRBs). We present the global properties of BAT GRBs based on their spectral and temporal characteristics. The BAT T90 and T50 durations peak at 80 and 20 s, respectively. The peak energy (Epeak) of about 60% of BAT GRBs is very likely to be less than 1.00 keV. We also present the BAT characteristics of GRBs with soft spectra, so called Xray flashes (XRFs). We will compare the BAT GRBs and XRFs parameter distribution to the other missions.

  8. Near-Earth Asteroid Follow-up Observations from the Astronomical Research Institute

    Science.gov (United States)

    Linder, Tyler R.

    2017-10-01

    The Astronomical Research Institute (ARI) operates eight telescopes ranging in size from 0.41m to 1.3m. These telescopes are dedicated to the astrometric recovery and arc-extension of Near-Earth Asteroids (NEAs). Four telescopes are located outside Westfield, Illinois, USA (0.61, 0.76, 0.81, 1.3m) while the other four telescopes are at Cerro Tololo Inter-American Observatory (0.41, 0.61, 0.61, 1.0m).The increase in NEA discovery from PanSTARRS and Catalina Sky Survey continues to escalate the nightly demand for newly discovered NEA follow-up. ARI has developed a new protocol which allows the discovery rate to increase fivefold without the need for additional telescopes.ARI’s new secondary priority is to provide spectra and spectrophotometry observations of the brightest newly discovered NEAs. Proposed methods and procedures will be discussed so that other NEA researchers may have access to the results without a peer-reviewed delay.

  9. Optical follow-up observations of Locburst GRB locations with OMC test camera

    International Nuclear Information System (INIS)

    Rezek, Tomas; Hudec, Rene; Soldan, Jan; Hroch, Filip; Mas-Hesse, Miguel; Gimenez, Alvaro

    1999-01-01

    The test camera of the Optical Monitoring Camera (OMC) experiment for INTEGRAL spacecraft achieving the angular pixel size of 18 arcsec and the field of view 7.5 deg. x 5.1 deg. has been successfully developed and tested at the Astronomical Institute Ondrejov. The test camera is able to provide imaging down to 15 mag over the whole field of view within one exposure of 300 seconds. Although developed primarily to test the OMC performance and help with software development, this device is ideally suitable for the use as ground-based camera for the sites where Compton Gamma-Ray Observatory BATSE Locburst triggers are followed-up in optical waveband and also for wide-field sky monitoring in general. The low cost of this camera makes it possible to duplicate the system to a number of observing sites. A chart and a corresponding CCD-image for the BACODINE Locburst Position 6368 taken with OMC test camera at Ondrejov observatory are also presented. The image taken 18 hours after the trigger was computer-blinked with the frame taken 30 days later. No optical activity has been found down to 13.5 mag

  10. Prospective observation of CAD/CAM titanium ceramic single crowns: a three-year follow up.

    Science.gov (United States)

    Boeckler, Arne F; Lee, Heeje; Stadler, Anke; Setz, Jürgen M

    2009-11-01

    Computer-aided design/computer-aided manufacturing (CAD/CAM) titanium ceramic restorations were developed with the potential for replacing expensive, high noble metal ceramic restorations. However, there is a lack of information about the clinical performance of CAD/CAM titanium ceramic single crowns. The purpose of this study was to evaluate CAD/CAM titanium ceramic single crowns after 3 years in function. A total of 41 crowns were fabricated for 21 patients. The titanium copings were CAD/CAM milled (Everest CAD/CAM system) with an even thickness of 0.5 mm, and low-fusing veneering porcelain (Vita Titanium Porcelain) was added incrementally. The crowns were cemented using zinc phosphate cement after confirming that there were no mechanical and biological complications. The patients were recalled at 12, 24, and 36 months after cementation to examine the presence of any complications and measure periodontal parameters such as probing depth (PD), bleeding on probing (BOP), and plaque index (PI). The success and survival rates were estimated using the Kaplan-Meier analysis. The success rate of CAD/CAM titanium ceramic crowns with regard to mechanical complications was 82.3% (95% confidence interval: 71.2% to 95.1%). The cumulative survival rate of the crowns was 94.9% (95% confidence interval: 88.3% to 100%) after 3 years. No biological complications were observed. At the end of the follow up, PD was 2.93 mm, percentile of surface with BOP was 29.2, and PI was 0.31. The clinical performances of the CAD/CAM titanium ceramic crowns for 3 years were acceptable, with no biologic complications and a high cumulative survival rate.

  11. VizieR Online Data Catalog: Kepler follow-up observation program. I. Imaging (Furlan+, 2017)

    Science.gov (United States)

    Furlan, E.; Ciardi, D. R.; Everett, M. E.; Saylors, M.; Teske, J. K.; Horch, E. P.; Howell, S. B.; van Belle, G. T.; Hirsch, L. A.; Gautier, T. N.; Adams, E. R.; Barrado, D.; Cartier, K. M. S.; Dressing, C. D.; Dupree, A. K.; Gilliland, R. L.; Lillo-Box, J.; Lucas, P. W.; Wang, J.

    2017-07-01

    We present results from six years of follow-up imaging observations of KOI host stars, including work done by teams from the Kepler Community Follow-up Observation Program (CFOP; https://exofop.ipac.caltech.edu/cfop.php) and by other groups. Several observing facilities were used to obtain high-resolution images of KOI host stars. Table1 lists the various telescopes, instruments used, filter bandpasses, typical Point Spread Function (PSF) widths, number of targets observed, and main references for the published results. The four main observing techniques employed are adaptive optics (Keck, Palomar, Lick, MMT), speckle interferometry (Gemini North, WIYN, DCT), lucky imaging (Calar Alto), and imaging from space with HST. A total of 3557 KOI host stars were observed at 11 facilities with 9 different instruments, using filters from the optical to the near-infrared. In addition, 10 of these stars were also observed at the 8m Gemini North telescope by Ziegler et al. 2016 (AJ accepted, arXiv:1605.03584) using laser guide star adaptive optics. The largest number of KOI host stars (3320) were observed using Robo-AO at the Palomar 1.5m telescope (Baranec et al. 2014ApJ...790L...8B; Baranec et al. 2016, Cat. J/AJ/152/18; Law et al. 2014, Cat. J/ApJ/791/35; Ziegler et al. 2016, AJ accepted, arXiv:1605.03584). A total of 8332 observations were carried out from 2009 September to 2015 October covering 3557 stars. We carried out observations at the Keck, Palomar, and Lick Observatory using the facility adaptive optics systems and near-infrared cameras from 2009 to 2015. At Keck, we observed with the 10m Keck II telescope and Near-Infrared Camera, second generation (NIRC2). The pixel scale of NIRC2 was 0.01''/pixel, resulting in a field of view of about 10''*10''. We observed our targets in a narrow K-band filter, Brγ, which has a central wavelength of 2.1686μm. In most cases, when a companion was detected, we also observed the target in a narrow-band J filter, Jcont, which is

  12. [Follow-up observation of photoselective vaporization of prostate for treatment of benign prostatic hyperplasia within five years].

    Science.gov (United States)

    Liu, Cui-long; Ouyang, Yun; Guo, Jian-jun; Zhou, Mao-jun; Lu, Er-xun; Guan, Wei-min

    2013-02-01

    To evaluate the efficacy and safty of photoselective vaporization of prostate (PVP) in the treatment of benign prostatic hyperplasia with obstruction within 5 years. From December 2004 to December 2009, there were 782 cases have been except for neurogenic bladder dysfunction and prostate cancer, who received PVP surgical treatment of BPH. The surgical conditions and postoperative follow-up data were recorded and the follow-up cut-off time for surgery after 5 years. A total of 782 patients with BPH who underwent PVP were included in this retrospective study. The operation in 740 cases was successfully completed at one time. But in other 42 cases, the twice operation was performed. The mean operation time was (85 ± 38) minutes, and the mean energy delivery was (355 ± 124) kJ. The mean catheterization and postoperative hospitalization time was (2.3 ± 1.7) days and (5.2 ± 2.6) days, respectively. No severe intraoperative complications were observed. The mean follow-up was (44.1 ± 19.3) months. The shortest follow-up was 6 months. The longest follow-up was 5 years. Complete follow-up data were available for 398 of the 782 patients. Of the 398 patients followed up for 5 years, the mean international prostate symptom score after 5 years was 12.8 ± 6.9, quality of life score was 2.2 ± 1.6, maximal flow rate was (14.5 ± 2.4) ml/s, and residual urine volume was 58 ml (M50). The retreatment rate because of BPH was 2.3% (9/398). Urethral stricture and bladder neck contracture were observed in 1.5% and 0.5% of the patients, respectively. PVP has demonstrated remarkably consistent results for objective and subjective voiding parameters. Its late complication is rare and retreatment rate is low.

  13. Using the 2-MASS photometric redshift survey to optimize LIGO follow-up observations

    Science.gov (United States)

    Antolini, Elisa; Heyl, Jeremy S.

    2016-10-01

    The initial discovery of Laser Interferometer Gravitational-Wave Observatory (LIGO) on 2015 September 14 was the inspiral merger and ring-down of the black hole binary at a distance of about 500 Mpc or a redshift of about 0.1. The search for electromagnetic counterparts for the inspiral of binary black holes is impeded by coarse initial source localizations and a lack of a compelling model for the counterpart; therefore, rapid electromagnetic follow-up is required to understand the astrophysical context of these sources. Because astrophysical sources of gravitational radiation are likely to reside in galaxies, it would make sense to search first in regions where the LIGO-Virgo probability is large and where the density of galaxies is large as well. Under the assumption that the probability of a gravitational-wave event from a given region of space is proportional to the density of galaxies within the probed volume, one can calculate an improved localization of the position of the source simply by multiplying the LIGO-Virgo skymap by the density of galaxies in the range of redshifts. We propose using the 2-MASS photometric redshift galaxy catalogue for this purpose and demonstrate that using it can dramatically reduce the search region for electromagnetic counterparts.

  14. Optimization of the Swift X-Ray Follow-Up of Advanced LIGO and Virgo Gravitational Wave Triggers in 2015-16

    Science.gov (United States)

    Evans, P. A.; Osborne, J. P.; Kennea, J. A.; Campana, S.; O'Brien, P. T.; Tanvir, N. R.; Racusin, J. L.; Burrows, D. N.; Cenko, S. B.; Gehrels, N.

    2015-01-01

    One of the most exciting near-term prospects in physics is the potential discovery of gravitational waves by the Advanced LIGO and Virgo detectors. To maximize both the confidence of the detection and the science return, it is essential to identify an electromagnetic counterpart.This is not trivial, as the events are expected to be poorly localized, particularly in the near-term, with error regions covering hundreds or even thousands of square degrees. In this paper, we discuss the prospects for finding an X-ray counterpart to a gravitational wave trigger with the Swift X-ray Telescope, using the assumption that the trigger is caused by a binary neutron star merger which also produces a short gamma-ray burst. We show that it is beneficial to target galaxies within the GW error region, highlighting the need for substantially complete galaxy catalogues out to distances of 300 Mpc. We also show that nearby, on-axis short GRBs are either extremely rare, or are systematically less luminous than those detected to date. We consider the prospects for detecting afterglow emission from an off-axis GRB which triggered the GW facilities, finding that the detectability, and the best time to look,are strongly dependent on the characteristics of the burst such as circumburst density and our viewing angle.

  15. No efficacy of annual gynaecological screening in BRCA1/2 mutation carriers; an observational follow-up study

    NARCIS (Netherlands)

    Hermsen, B. B. J.; Olivier, R. I.; Verheijen, R. H. M.; van Beurden, M.; de Hullu, J. A.; Massuger, L. F.; Burger, C. W.; Brekelmans, C. T.; Mourits, M. J.; de Bock, G. H.; Gaarenstroom, K. N.; van Boven, H. H.; Mooij, T. M.; Rookus, M. A.

    2007-01-01

    BRCA1/ 2 mutation carriers are offered gynaecological screening with the intention to reduce mortality by detecting ovarian cancer at an early stage. We examined compliance and efficacy of gynaecological screening in BRCA1/ 2 mutation carriers. In this multicentre, observational, follow-up study we

  16. XTE J1701-407 INTEGRAL and Swift observations

    DEFF Research Database (Denmark)

    Soldi, S.; Beckmann, V.; Eckert, D.

    2008-01-01

    detected by IBIS/ISGRI in the 20-80 keV band. The source was always outside the field of view of the X-ray monitor JEM-X. In the latest observation, the source was also detected in the 40-80 keV band with 14 ± 2 mCrab. Simultaneous to this observation a Swift ToO was performed, starting at 2008-10-18T14......:27 with an on-source time of 1.7 ksec. The combined spectrum of Swift/XRT and IBIS/ISGRI (33 ksec) can be represented by an absorbed power law with intrinsic NH = 2.2e22 1/cm^2 and photon index 2.1 ± 0.1. The model flux in the 2-50 keV band is 3e-10 erg/cm^2/sec. Assuming a maximum distance of 6 kpc (Linares et...

  17. Swift observations of Nova Scuti 2017

    Science.gov (United States)

    Kuin, N. P. M.; Page, K. L.; Williams, S. C.; Darnley, M. J.; Nelson, T. J.; Osborne, J.

    2017-08-01

    Nova Sct 2017 (ASASSN-17hx/ASASSN-17ib) went into eruption on 2017-06-19.41 (hereafter taken as Day 0), as reported on the ASAS SN transient page (see also ATEL #10523,#10524) Spectroscopic confirmation (ATEL #10527,#10542) observed emission in H and He I, and in N II as well as Fe II. The ASASSN light curve data show a peak of V = 8.75 on 2017, July 30, day 40.867.

  18. Strumal carcinoid of the ovary: ultrastructural observations and long-term follow-up study.

    Science.gov (United States)

    Hart, W R; Regezi, J A

    1978-03-01

    Herein is reported an ovarian strumal carcinoid in a mature tetratoma from a 54-year-old women. Ultrastructural examination revealed numerous electron-dense intracellular granules, which were intrepreted as neurosecretory granules. They corresponded to argyrophil granules observed by light microscopy and were identified within neoplastic cells arranged in both follicular and trabecular patterns. These findings corroborate the contention that the strumal carcinoid itself is a pure neuroendocrine tumor devoid of thyroid follicular epithelium, but do not disprove its possible origin from parafollicular cells of adjacent teratomatous thyroid tissue. There was no recurrence of tumor during the 20 1/2 years the patient was followed.

  19. Results of optical follow-up observations of advanced LIGO triggers from O1 in the southern hemisphere

    Science.gov (United States)

    Beroiz, Martin; Colazo, Carlos; Diaz, Mario; Dominguez, Mariano; Garcia Lambas, Diego; Gurovich, Sebastian; Lares, Marcelo; Macri, Lucas; Penuela, Tania; Rodriguez, Horacio; Sanchez, Bruno; Toros Collaboration

    2016-03-01

    We report on observations related to the follow-up of LIGO VIRGO collaboration triggers released to participating astronomers during the First Observation Run 1 (O1) from September 18, 2015 to January 12, 2016, performed by the TOROS collaboration. The Transient Optical Robotic Observatory of the South (TOROS) collaboration operated telescopes located in two different sites in Argentina: one at the Estación Astrofísica Bosque Alegre in Cordoba, and the other one located in Cordón Macón, Salta. In this communication we describe the main characteristics of the campaign sustained during O1 and the plans for continuing observation in the future.

  20. The XXL Survey I. Scientific Motivations - Xmm-Newton Observing Plan - Follow-up Observations and Simulation Programme

    Science.gov (United States)

    Pierre, M.; Pacaud, F.; Adami, C.; Alis, S.; Altieri, B.; Baran, N.; Benoist, C.; Birkinshaw, M.; Bongiorno, A.; Bremer, M. N.; hide

    2016-01-01

    The quest for the cosmological parameters that describe our universe continues to motivate the scientific community to undertake very large survey initiatives across the electromagnetic spectrum. Over the past two decades, the Chandra and XMM-Newton observatories have supported numerous studies of X-ray-selected clusters of galaxies, active galactic nuclei (AGNs), and the X-ray background. The present paper is the first in a series reporting results of the XXL-XMM survey; it comes at a time when the Planck mission results are being finalized. Aims. We present the XXL Survey, the largest XMM programme totaling some 6.9 Ms to date and involving an international consortium of roughly 100 members. The XXL Survey covers two extragalactic areas of 25 deg2 each at a point-source sensitivity of approx. 5 x 10(exp 15) erg/s/sq cm in the [0.5-2] keV band (completeness limit). The surveys main goals are to provide constraints on the dark energy equation of state from the space-time-distribution of clusters of galaxies and to serve as a pathfinder for future, wide-area X-ray missions. We review science objectives, including cluster studies, AGN evolution, and large-scale structure, that are being conducted with the support of approximately 30 follow-up programs. Methods. We describe the 542 XMM observations along with the associated multi- and numerical simulation programmes. We give a detailed account of the X-ray processing steps and describe innovative tools being developed for the cosmological analysis. Results. The paper provides a thorough evaluation of the X-ray data, including quality controls, photon statistics, exposure and background maps, and sky coverage. Source catalogue construction and multi-associations are briefly described. This material will be the basis for the calculation of the cluster and AGN selection functions, critical elements of the cosmological and science analyses. Conclusions. The XXL multi- data set will have a unique lasting legacy value for

  1. Multiwavelength follow-up observations of the tidal disruption event candidate 2XMMi J184725.1-631724

    Science.gov (United States)

    Lin, Dacheng; Strader, Jay; Carrasco, Eleazar R.; Godet, Olivier; Grupe, Dirk; Webb, Natalie A.; Barret, Didier; Irwin, Jimmy A.

    2018-03-01

    The ultrasoft X-ray flare 2XMMi J184725.1-631724 was serendipitously detected in two XMM-Newton observations in 2006 and 2007, with a peak luminosity of 6 × 1043 erg s-1. It was suggested to be a tidal disruption event (TDE) because its position is consistent with the centre of an inactive galaxy. It is the only known X-ray TDE candidate whose X-ray spectra showed evidence of a weak steep power-law component besides a dominant supersoft thermal disc. We have carried out multiwavelength follow-up observations of the event. Multiple X-ray monitorings show that the X-ray luminosity has decayed significantly after 2011. Especially, in our deep Chandra observation in 2013, we detected a very faint counterpart that supports the nuclear origin of 2XMMi J184725.1-631724 but had an X-ray flux a factor of ˜1000 lower than in the peak of the event. Compared with follow-up ultraviolet (UV) observations, we found that there might be some enhanced UV emission associated with the TDE in the first XMM-Newton observation. We also obtained a high-quality UV-optical spectrum with the Southern Astrophysical Research (SOAR) Telescope and put a very tight constraint on the persistent nuclear activity, with a persistent X-ray luminosity expected to be lower than the peak of the flare by a factor of >2700. Therefore, our multiwavelength follow-up observations strongly support the TDE explanation of the event.

  2. The OmegaWhite survey for short-period variable stars - III: follow-up photometric and spectroscopic observations

    Science.gov (United States)

    Macfarlane, S. A.; Woudt, P. A.; Groot, P. J.; Ramsay, G.; Toma, R.; Motsoaledi, M.; Crause, L. A.; Gilbank, D. G.; O'Donoghue, D.; Potter, S. B.; Sickafoose, A. A.; van Gend, C.; Worters, H. L.

    2017-02-01

    We present photometric and spectroscopic follow-up observations of short-period variables discovered in the OmegaWhite survey, a wide-field high-cadence g-band synoptic survey targeting the Galactic Plane. We have used fast photometry on the SAAO 1.0- and 1.9-m telescopes to obtain light curves of 27 variables, and use these results to validate the period and amplitude estimates from the OmegaWhite processing pipeline. Furthermore, 57 sources (44 unique, 13 with new light curves) were selected for spectroscopic follow-up using either the SAAO 1.9-m telescope or the Southern African Large Telescope. We find that many of these variables have spectra which are consistent with being δ Scuti-type pulsating stars. At higher amplitudes, we detect four possible pulsating white dwarf/subdwarf sources and an eclipsing cataclysmic variable. Due to their rarity, these targets are ideal candidates for detailed follow-up studies. From spectroscopy, we confirm the symbiotic binary star nature of two variables identified as such in the SIMBAD database. We also report what could possibly be the first detection of the `Bump Cepheid' phenomena in a δ Scuti star, with OW J175848.21-271653.7 showing a pronounced 22 per cent amplitude dip lasting 3 min during each pulsational cycle peak. However, the precise nature of this target is still uncertain as it exhibits the spectral features of a B-type star.

  3. NIBLES - an HI census of stellar mass selected SDSS galaxies. II. Arecibo follow-up HI observations

    Science.gov (United States)

    Butcher, Z.; Schneider, S.; van Driel, W.; Lehnert, M. D.; Minchin, R.

    2016-11-01

    We obtained Arecibo Hi line follow-up observations of 154 of the 2600 galaxies in the Nançay Interstellar Baryons Legacy Extragalactic Survey (NIBLES) sample. These observations are on average four times more sensitive than the original observations at the Nançay Radio Telescope. The main goal of this survey is to characterize the underlying Hi properties of the NIBLES galaxies which were undetected or marginally detected at Nançay. Of the Nançay non-detections, 85% were either clearly or marginally detected at Arecibo, while 89% of the Nançay marginal detections were clearly detected. Based on the statistics of the detections relative to g-I color and r-band luminosity (Lr) distribution among our Arecibo observations, we anticipate 60% of our 867 Nançay non-detections and marginal detections could be detected at the sensitivity of our Arecibo observations. Follow-up observations of our low luminosity (Lr ALFALFA surveys respectively. Reduced spectra are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/596/A60

  4. The Sloan Digital Sky Survey-II Supernova Survey:Search Algorithm and Follow-up Observations

    Energy Technology Data Exchange (ETDEWEB)

    Sako, Masao; /Pennsylvania U. /KIPAC, Menlo Park; Bassett, Bruce; /Cape Town U. /South African Astron. Observ.; Becker, Andrew; /Washington U., Seattle, Astron. Dept.; Cinabro, David; /Wayne State U.; DeJongh, Don Frederic; /Fermilab; Depoy, D.L.; /Ohio State U.; Doi, Mamoru; /Tokyo U.; Garnavich, Peter M.; /Notre Dame U.; Craig, Hogan, J.; /Washington U., Seattle, Astron. Dept.; Holtzman, Jon; /New Mexico State U.; Jha, Saurabh; /Stanford U., Phys. Dept.; Konishi, Kohki; /Tokyo U.; Lampeitl, Hubert; /Baltimore, Space; Marriner, John; /Fermilab; Miknaitis, Gajus; /Fermilab; Nichol, Robert C.; /Portsmouth U.; Prieto, Jose Luis; /Ohio State U.; Richmond, Michael W.; /Rochester Inst.; Schneider, Donald P.; /Penn State U., Astron. Astrophys.; Smith, Mathew; /Portsmouth U.; SubbaRao, Mark; /Chicago U. /Tokyo U. /Tokyo U. /South African Astron. Observ. /Tokyo

    2007-09-14

    The Sloan Digital Sky Survey-II Supernova Survey has identified a large number of new transient sources in a 300 deg2 region along the celestial equator during its first two seasons of a three-season campaign. Multi-band (ugriz) light curves were measured for most of the sources, which include solar system objects, Galactic variable stars, active galactic nuclei, supernovae (SNe), and other astronomical transients. The imaging survey is augmented by an extensive spectroscopic follow-up program to identify SNe, measure their redshifts, and study the physical conditions of the explosions and their environment through spectroscopic diagnostics. During the survey, light curves are rapidly evaluated to provide an initial photometric type of the SNe, and a selected sample of sources are targeted for spectroscopic observations. In the first two seasons, 476 sources were selected for spectroscopic observations, of which 403 were identified as SNe. For the Type Ia SNe, the main driver for the Survey, our photometric typing and targeting efficiency is 90%. Only 6% of the photometric SN Ia candidates were spectroscopically classified as non-SN Ia instead, and the remaining 4% resulted in low signal-to-noise, unclassified spectra. This paper describes the search algorithm and the software, and the real-time processing of the SDSS imaging data. We also present the details of the supernova candidate selection procedures and strategies for follow-up spectroscopic and imaging observations of the discovered sources.

  5. The Detection of a Type IIn Supernova in Optical Follow-up Observations of IceCube Neutrino Events

    Science.gov (United States)

    Aartsen, M. G.; Abraham, K.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Altmann, D.; Anderson, T.; Archinger, M.; Arguelles, C.; Arlen, T. C.; Auffenberg, J.; Bai, X.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Becker Tjus, J.; Becker, K.-H.; Beiser, E.; BenZvi, S.; Berghaus, P.; Berley, D.; Bernardini, E.; Bernhard, A.; Besson, D. Z.; Binder, G.; Bindig, D.; Bissok, M.; Blaufuss, E.; Blumenthal, J.; Boersma, D. J.; Bohm, C.; Börner, M.; Bos, F.; Bose, D.; Böser, S.; Botner, O.; Braun, J.; Brayeur, L.; Bretz, H.-P.; Brown, A. M.; Buzinsky, N.; Casey, J.; Casier, M.; Cheung, E.; Chirkin, D.; Christov, A.; Christy, B.; Clark, K.; Classen, L.; Coenders, S.; Cowen, D. F.; Cruz Silva, A. H.; Daughhetee, J.; Davis, J. C.; Day, M.; de André, J. P. A. M.; De Clercq, C.; Dembinski, H.; De Ridder, S.; Desiati, P.; de Vries, K. D.; de Wasseige, G.; de With, M.; DeYoung, T.; Díaz-Vélez, J. C.; Dumm, J. P.; Dunkman, M.; Eagan, R.; Eberhardt, B.; Ehrhardt, T.; Eichmann, B.; Euler, S.; Evenson, P. A.; Fadiran, O.; Fahey, S.; Fazely, A. R.; Fedynitch, A.; Feintzeig, J.; Felde, J.; Filimonov, K.; Finley, C.; Fischer-Wasels, T.; Flis, S.; Fuchs, T.; Glagla, M.; Gaisser, T. K.; Gaior, R.; Gallagher, J.; Gerhardt, L.; Ghorbani, K.; Gier, D.; Gladstone, L.; Glüsenkamp, T.; Goldschmidt, A.; Golup, G.; Gonzalez, J. G.; Góra, D.; Grant, D.; Gretskov, P.; Groh, J. C.; Gross, A.; Ha, C.; Haack, C.; Haj Ismail, A.; Hallgren, A.; Halzen, F.; Hansmann, B.; Hanson, K.; Hebecker, D.; Heereman, D.; Helbing, K.; Hellauer, R.; Hellwig, D.; Hickford, S.; Hignight, J.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Holzapfe, K.; Homeier, A.; Hoshina, K.; Huang, F.; Huber, M.; Huelsnitz, W.; Hulth, P. O.; Hultqvist, K.; In, S.; Ishihara, A.; Jacobi, E.; Japaridze, G. S.; Jero, K.; Jurkovic, M.; Kaminsky, B.; Kappes, A.; Karg, T.; Karle, A.; Kauer, M.; Keivani, A.; Kelley, J. L.; Kemp, J.; Kheirandish, A.; Kiryluk, J.; Kläs, J.; Klein, S. R.; Kohnen, G.; Koirala, R.; Kolanoski, H.; Konietz, R.; Koob, A.; Köpke, L.; Kopper, C.; Kopper, S.; Koskinen, D. J.; Kowalski, M.; Krings, K.; Kroll, G.; Kroll, M.; Kunnen, J.; Kurahashi, N.; Kuwabara, T.; Labare, M.; Lanfranchi, J. L.; Larson, M. J.; Lesiak-Bzdak, M.; Leuermann, M.; Leuner, J.; Lünemann, J.; Madsen, J.; Maggi, G.; Mahn, K. B. M.; Maruyama, R.; Mase, K.; Matis, H. S.; Maunu, R.; McNally, F.; Meagher, K.; Medici, M.; Meli, A.; Menne, T.; Merino, G.; Meures, T.; Miarecki, S.; Middell, E.; Middlemas, E.; Miller, J.; Mohrmann, L.; Montaruli, T.; Morse, R.; Nahnhauer, R.; Naumann, U.; Niederhausen, H.; Nowicki, S. C.; Nygren, D. R.; Obertacke, A.; Olivas, A.; Omairat, A.; O'Murchadha, A.; Palczewski, T.; Pandya, H.; Paul, L.; Pepper, J. A.; Pérez de los Heros, C.; Pfendner, C.; Pieloth, D.; Pinat, E.; Posselt, J.; Price, P. B.; Przybylski, G. T.; Pütz, J.; Quinnan, M.; Rädel, L.; Rameez, M.; Rawlins, K.; Redl, P.; Reimann, R.; Relich, M.; Resconi, E.; Rhode, W.; Richman, M.; Richter, S.; Riedel, B.; Robertson, S.; Rongen, M.; Rott, C.; Ruhe, T.; Ryckbosch, D.; Saba, S. M.; Sabbatini, L.; Sander, H.-G.; Sandrock, A.; Sandroos, J.; Sarkar, S.; Schatto, K.; Scheriau, F.; Schimp, M.; Schmidt, T.; Schmitz, M.; Schoenen, S.; Schöneberg, S.; Schönwald, A.; Schukraft, A.; Schulte, L.; Seckel, D.; Seunarine, S.; Shanidze, R.; Smith, M. W. E.; Soldin, D.; Spiczak, G. M.; Spiering, C.; Stahlberg, M.; Stamatikos, M.; Stanev, T.; Stanisha, N. A.; Stasik, A.; Stezelberger, T.; Stokstad, R. G.; Stössl, A.; Strahler, E. A.; Ström, R.; Strotjohann, N. L.; Sullivan, G. W.; Sutherland, M.; Taavola, H.; Taboada, I.; Ter-Antonyan, S.; Terliuk, A.; Tešić, G.; Tilav, S.; Toale, P. A.; Tobin, M. N.; Tosi, D.; Tselengidou, M.; Turcati, A.; Unger, E.; Usner, M.; Vallecorsa, S.; van Eijndhoven, N.; Vandenbroucke, J.; van Santen, J.; Vanheule, S.; Veenkamp, J.; Vehring, M.; Voge, M.; Vraeghe, M.; Walck, C.; Wallraff, M.; Wandkowsky, N.; Weaver, Ch.; Wendt, C.; Westerhoff, S.; Whelan, B. J.; Whitehorn, N.; Wichary, C.; Wiebe, K.; Wiebusch, C. H.; Wille, L.; Williams, D. R.; Wissing, H.; Wolf, M.; Wood, T. R.; Woschnagg, K.; Xu, D. L.; Xu, X. W.; Xu, Y.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Zarzhitsky, P.; Zoll, M.; IceCube Collaboration; Ofek, Eran O.; Kasliwal, Mansi M.; Nugent, Peter E.; Arcavi, Iair; Bloom, Joshua S.; Kulkarni, Shrinivas R.; Perley, Daniel A.; Barlow, Tom; Horesh, Assaf; Gal-Yam, Avishay; Howell, D. A.; Dilday, Ben; PTF Collaboration; Evans, Phil A.; Kennea, Jamie A.; Swift Collaboration; Burgett, W. S.; Chambers, K. C.; Kaiser, N.; Waters, C.; Flewelling, H.; Tonry, J. L.; Rest, A.; Smartt, S. J.; Pan-STARRS1 Science Consortium

    2015-09-01

    The IceCube neutrino observatory pursues a follow-up program selecting interesting neutrino events in real-time and issuing alerts for electromagnetic follow-up observations. In 2012 March, the most significant neutrino alert during the first three years of operation was issued by IceCube. In the follow-up observations performed by the Palomar Transient Factory (PTF), a Type IIn supernova (SN IIn) PTF12csy was found 0.°2 away from the neutrino alert direction, with an error radius of 0.°54. It has a redshift of z = 0.0684, corresponding to a luminosity distance of about 300 Mpc and the Pan-STARRS1 survey shows that its explosion time was at least 158 days (in host galaxy rest frame) before the neutrino alert, so that a causal connection is unlikely. The a posteriori significance of the chance detection of both the neutrinos and the SN at any epoch is 2.2σ within IceCube's 2011/12 data acquisition season. Also, a complementary neutrino analysis reveals no long-term signal over the course of one year. Therefore, we consider the SN detection coincidental and the neutrinos uncorrelated to the SN. However, the SN is unusual and interesting by itself: it is luminous and energetic, bearing strong resemblance to the SN IIn 2010jl, and shows signs of interaction of the SN ejecta with a dense circumstellar medium. High-energy neutrino emission is expected in models of diffusive shock acceleration, but at a low, non-detectable level for this specific SN. In this paper, we describe the SN PTF12csy and present both the neutrino and electromagnetic data, as well as their analysis.

  6. Results of Long-Term Follow-Up Observations of Blepharoptosis Correction Using the Palmaris Longus Tendon

    Science.gov (United States)

    Shin, YongHo

    2008-01-01

    Background The frontalis sling procedure is a useful approach for correcting severe blepharoptosis. However, blepharoptosis often recurs after corrective surgery using the tensor fascia lata. Good results without recurrence after a modified Fox method were obtained using the palmaris longus tendon. This study examined the safety and validity of the surgical method using the palmaris longus tendon through long-term follow-up observations. Methods To reduce the rate of recurrence, the highest point on the pentagon of the Fox method was fixed to the frontalis fascia and frontalis muscle. It was fixed once again to the area 1 cm above the highest point. This approach remarkably reduces the incidence of recurrence by fixing the pentagon of the Fox method not only to the palmaris longus tendon but also to the frontalis fascia and again to the frontalis muscle. A modified Fox method using the palmaris longus tendon was used to treat 16 eyelids of 10 patients. A senior surgeon performed the procedure in all cases under local anesthesia. Results The mean follow-up period was 51 months (range = 18–86 months). There was no case of blepharoptosis recurrence and a good field of view was secured after surgery. Long-term follow-up revealed that the visual field had been well secured with a mean MRD1 of 3.1 mm. The eyelids were well maintained without any postoperative adverse reaction such as exposure keratitis. Conclusion The palmaris longus tendon as useful donor material does not lead to recurrence of blepharoptosis, which is often encountered when the tensor fascia lata is used. The modified Fox method using the palmaris longus tendon can be an effective and valid surgical approach that produces both immediate and long-term results. PMID:18446402

  7. Joint Swift XRT and NuSTAR Observations of TXS 0506+056

    Science.gov (United States)

    Fox, D. B.; DeLaunay, J. J.; Keivani, A.; Evans, P. A.; Turley, C. F.; Kennea, J. A.; Cowen, D. F.; Osborne, J. P.; Santander, M.; Marshall, F. E.

    2017-10-01

    We have carried out joint Swift and NuSTAR observations of the BL Lac-type blazar TXS 0506+056, identified in our previous Swift XRT observations (GCN #21930) as one of nine bright X-ray sources within the localization region of the likely-cosmic IceCube EHE neutrino IceCube-170922A (GCN #21916).

  8. An observational study with long-term follow-up of canine cognitive dysfunction: clinical characteristics, survival, and risk factors.

    Science.gov (United States)

    Fast, R; Schütt, T; Toft, N; Møller, A; Berendt, M

    2013-01-01

    Canine cognitive dysfunction (CCD) is a neurodegenerative condition affecting geriatric dogs and sharing several characteristics with human Alzheimer's disease (AD). CCD manifests as alterations of behavioral patterns and daily routines. Clinical signs are associated with neurodegenerative changes (eg, cortical atrophy and amyloid-beta deposits). To investigate clinical characteristics, survival, and risk factors with CCD. Vitamin E was investigated as a potential marker of CCD. Ninety-four dogs >8 years of age were investigated with a validated CCD questionnaire and allocated to CCD, borderline CCD (b-CCD) and non-CCD groups. The dogs were included in 2008-2009 and followed up in an observational study until follow-up in 2012. Four key clinical signs dominated in dogs with CCD: sleeping during the day and restless at night, decreased interaction, disorientation at home, and anxiety. A number of borderline CCD cases developed into CCD over time indicating that a prodromal stage of CCD may exist. CCD did not influence survival negatively. Small breeds did not show better survival than large breeds (P = .055) and there was no difference between sexes (P = .99). A few key questions addressing sleep-wake cycle, interaction, and signs of confusion and anxiety can be used as a clinical marker of CCD. Special attention should be paid to anxiety in dogs with CCD because it may be especially stressful to both dog and owner. Dogs with CCD seem to have a good chance of living a full lifespan if supported by the veterinarian and the owner. Copyright © 2013 by the American College of Veterinary Internal Medicine.

  9. Distant clusters of galaxies in the 2XMM/SDSS footprint: follow-up observations with the LBT

    Science.gov (United States)

    Rabitz, A.; Lamer, G.; Schwope, A.; Takey, A.

    2017-11-01

    Context. Galaxy clusters at high redshift are important to test cosmological models and models for the growth of structure. They are difficult to find in wide-angle optical surveys, however, leaving dedicated follow-up of X-ray selected candidates as one promising identification route. Aims: We aim to increase the number of galaxy clusters beyond the SDSS-limit, z 0.75. Methods: We compiled a list of extended X-ray sources from the 2XMMp catalogue within the footprint of the Sloan Digital Sky Survey. Fields without optical counterpart were selected for further investigation. Deep optical imaging and follow-up spectroscopy were obtained with the Large Binocular Telescope, Arizona (LBT), of those candidates not known to the literature. Results: From initially 19 candidates, selected by visually screening X-ray images of 478 XMM-Newton observations and the corresponding SDSS images, 6 clusters were found in the literature. Imaging data through r,z filters were obtained for the remaining candidates, and 7 were chosen for multi-object (MOS) spectroscopy. Spectroscopic redshifts, optical magnitudes, and X-ray parameters (flux, temperature, and luminosity) are presented for the clusters with spectroscopic redshifts. The distant clusters studied here constitute one additional redshift bin for studies of the LX-T relation, which does not seem to evolve from high to low redshifts. Conclusions: The selection method of distant galaxy clusters presented here was highly successful. It is based solely on archival optical (SDSS) and X-ray (XMM-Newton) data. Out of 19 selected candidates, 6 of the 7 candidates selected for spectroscopic follow-up were verified as distant clusters, a further candidate is most likely a group of galaxies at z 1.21. Out of the remaining 12 candidates, 6 were known previously as galaxy clusters, one object is a likely X-ray emission from an AGN radio jet, and for 5 we see no clear evidence for them to be high-redshift galaxy clusters. Based on

  10. Assessment of cataract surgical outcomes in settings where follow-up is poor: PRECOG, a multicentre observational study

    OpenAIRE

    Prof. Nathan Congdon, MD; Xixi Yan, MD; Van Lansingh, MD; Alemayehu Sisay, MD; Andreas Müller, PhD; Ving Chan, OD; Ling Jin, MS; Mirjam E Meltzer, PhD; Sasipriya M Karumanchi, MHM; Chunhong Guan, MSc; Quy Vuong, MD; Nelson Rivera, OD; Joan McCleod-Omawale, PhD; Prof. Mingguang He, MD

    2013-01-01

    Background: Poor follow-up after cataract surgery in developing countries makes assessment of operative quality uncertain. We aimed to assess two strategies to measure visual outcome: recording the visual acuity of all patients 3 or fewer days postoperatively (early postoperative assessment), and recording that of only those patients who returned for the final follow-up examination after 40 or more days without additional prompting. Methods: Each of 40 centres in ten countries in Asia, Afr...

  11. Multiband Diagnostics of Unidentified 1FGL Sources with Suzaku and Swift X-Ray Observations

    Science.gov (United States)

    Takeuchi, Y.; Kataoka, J.; Maeda, K.; Takahashi, Y.; Nakamori, T.; Tahara, M.

    2013-10-01

    We have analyzed all the archival X-ray data of 134 unidentified (unID) gamma-ray sources listed in the first Fermi/LAT (1FGL) catalog and subsequently followed up by the Swift/XRT. We constructed the spectral energy distributions (SEDs) from radio to gamma-rays for each X-ray source detected, and tried to pick up unique objects that display anomalous spectral signatures. In these analyses, we target all the 1FGL unID sources, using updated data from the second Fermi/LAT (2FGL) catalog on the Large Area Telescope (LAT) position and spectra. We found several potentially interesting objects, particularly three sources, 1FGL J0022.2-1850, 1FGL J0038.0+1236, and 1FGL J0157.0-5259, which were then more deeply observed with Suzaku as a part of an AO-7 program in 2012. We successfully detected an X-ray counterpart for each source whose X-ray spectra were well fitted by a single power-law function. The positional coincidence with a bright radio counterpart (currently identified as an active galactic nucleus, AGN) in the 2FGL error circles suggests these sources are definitely the X-ray emission from the same AGN, but their SEDs show a wide variety of behavior. In particular, the SED of 1FGL J0038.0+1236 is not easily explained by conventional emission models of blazars. The source 1FGL J0022.2-1850 may be in a transition state between a low-frequency peaked and a high-frequency peaked BL Lac object, and 1FGL J0157.0-5259 could be a rare kind of extreme blazar. We discuss the possible nature of these three sources observed with Suzaku, together with the X-ray identification results and SEDs of all 134 sources observed with the Swift/XRT.

  12. LOW FALSE POSITIVE RATE OF KEPLER CANDIDATES ESTIMATED FROM A COMBINATION OF SPITZER AND FOLLOW-UP OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Désert, Jean-Michel; Brown, Timothy M. [CASA, Department of Astrophysical and Planetary Sciences, University of Colorado, 389-UCB, Boulder, CO 80309 (United States); Charbonneau, David; Torres, Guillermo; Fressin, François; Ballard, Sarah; Latham, David W. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Bryson, Stephen T.; Borucki, William J. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Knutson, Heather A. [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125 (United States); Batalha, Natalie M. [San Jose State University, San Jose, CA 95192 (United States); Deming, Drake [Department of Astronomy, University of Maryland, College Park, MD 20742-2421 (United States); Ford, Eric B. [University of Florida, Gainesville, FL 32611 (United States); Fortney, Jonathan J. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Gilliland, Ronald L. [Center for Exoplanets and Habitable Worlds, The Pennsylvania State University, University Park, PA 16802 (United States); Seager, Sara, E-mail: desert@colorado.edu [Massachusetts Institute of Technology, Cambridge, MA 02159 (United States)

    2015-05-01

    NASA’s Kepler mission has provided several thousand transiting planet candidates during the 4 yr of its nominal mission, yet only a small subset of these candidates have been confirmed as true planets. Therefore, the most fundamental question about these candidates is the fraction of bona fide planets. Estimating the rate of false positives of the overall Kepler sample is necessary to derive the planet occurrence rate. We present the results from two large observational campaigns that were conducted with the Spitzer Space Telescope during the the Kepler mission. These observations are dedicated to estimating the false positive rate (FPR) among the Kepler candidates. We select a sub-sample of 51 candidates, spanning wide ranges in stellar, orbital, and planetary parameter space, and we observe their transits with Spitzer at 4.5 μm. We use these observations to measures the candidate’s transit depths and infrared magnitudes. An authentic planet produces an achromatic transit depth (neglecting the modest effect of limb darkening). Conversely a bandpass-dependent depth alerts us to the potential presence of a blending star that could be the source of the observed eclipse: a false positive scenario. For most of the candidates (85%), the transit depths measured with Kepler are consistent with the transit depths measured with Spitzer as expected for planetary objects, while we find that the most discrepant measurements are due to the presence of unresolved stars that dilute the photometry. The Spitzer constraints on their own yield FPRs between 5% and depending on the Kepler Objects of Interest. By considering the population of the Kepler field stars, and by combining follow-up observations (imaging) when available, we find that the overall FPR of our sample is low. The measured upper limit on the FPR of our sample is 8.8% at a confidence level of 3σ. This observational result, which uses the achromatic property of planetary transit signals that is not investigated

  13. Assessment of cataract surgical outcomes in settings where follow-up is poor: PRECOG, a multicentre observational study.

    Science.gov (United States)

    Congdon, Nathan; Yan, Xixi; Lansingh, Van; Sisay, Alemayehu; Müller, Andreas; Chan, Ving; Jin, Ling; Meltzer, Mirjam E; Karumanchi, Sasipriya M; Guan, Chunhong; Vuong, Quy; Rivera, Nelson; McCleod-Omawale, Joan; He, Mingguang

    2013-07-01

    Poor follow-up after cataract surgery in developing countries makes assessment of operative quality uncertain. We aimed to assess two strategies to measure visual outcome: recording the visual acuity of all patients 3 or fewer days postoperatively (early postoperative assessment), and recording that of only those patients who returned for the final follow-up examination after 40 or more days without additional prompting. Each of 40 centres in ten countries in Asia, Africa, and Latin America recruited 40-120 consecutive surgical cataract patients. Operative-eye best-corrected visual acuity and uncorrected visual acuity were recorded before surgery, 3 or fewer days postoperatively, and 40 or more days postoperatively. Clinics logged whether each patient had returned for the final follow-up examination without additional prompting, had to be actively encouraged to return, or had to be examined at home. Visual outcome for each centre was defined as the proportion of patients with uncorrected visual acuity of 6/18 or better minus the proportion with uncorrected visual acuity of 6/60 or worse, and was calculated for each participating hospital with results from the early assessment of all patients and the late assessment of only those returning unprompted, with results from the final follow-up assessment for all patients used as the standard. Of 3708 participants, 3441 (93%) had final follow-up vision data recorded 40 or more days after surgery, 1831 of whom (51% of the 3581 total participants for whom mode of follow-up was recorded) had returned to the clinic without additional prompting. Visual outcome by hospital from early postoperative and final follow-up assessment for all patients were highly correlated (Spearman's rs=0·74, pFred Hollows Foundation, Helen Keller International, International Association for the Prevention of Blindness Latin American Office, Aravind Eye Care System. Copyright © 2013 Congdon et al. Open Access article distributed under the terms of

  14. Treatment and follow-up results of children with electrical burn who observed in burn intensive care unit

    Directory of Open Access Journals (Sweden)

    Çiğdem Aliosmanoğlu

    2011-06-01

    Full Text Available Electrical burns are infrequent relative to other injuries, but they are associated with high morbidity and mortality. The aim of this study was to assess management and follow-up results of pediatric patients’ who observed in intensive care unit and also review the precautions for preventing electrical burns.Materials and methods: Totally 22 patients aged under 17 years who were observed in the burn intensive care unit of Şanlıurfa Education and Research Hospital during the period between July 2009-October 2010. Cases were investigated retrospectively. The patients’ age, gender, total burn surface area, length of stay in hospital, musculo-skeletal system complication, cardiovascular system complication, kidney damage and attempts were recorded.Results: Of the 22 cases, 19 (86.3% were male and 3 (13.7% were female. The mean age of the patients was 11.5 years. In 10 (45.4% children burns were occurred in workplace and working area and 12 (54.6% were occurred in the home environment. Depth of burns were third degree in 10 (45.4% children and second degree in 12 (54.6%. The mean percentage of burn surface area was 25.9%. The mean length of stay in hospital was 17 days. Debridement and grafting were performed to 12 (54.6% cases and 10 (45.4% children were treated with dressings. No patient had increased creatinine kinase levels, oliguria, myoglobuinuria and arrhythmia. The mean hospitalization time was 17 days.Conclusion: Nearly half of patients underwent debridement plus grafting. None of our patients developed renal failure other severe system dysfunction.

  15. Prompt Optical Observations of GRB 050319 with the Swift UVOT

    Science.gov (United States)

    Mason, K. O.; Blustin, A. J.; Boyd, P.; Holland, S. T.; Page, M. J.; Roming, P.; Still, M.; Zhang, B.; Breeveld, A.; de Pasquale, M.; Gehrels, N.; Gronwall, C.; Hunsberger, S.; Ivanushkina, M.; Landsman, W.; McGowan, K.; Nousek, J.; Poole, T.; Rhoads, J.; Rosen, S.; Schady, P.

    2006-03-01

    The UVOT telescope on the Swift observatory has detected optical afterglow emission from GRB 050319. The flux declined with a power-law slope of α=-0.57 between the start of observations some 230 s after the burst onset (90 s after the burst trigger) until it faded below the sensitivity threshold of the instrument after ~5×104 s. There is no evidence for the rapidly declining component in the early light curve that is seen at the same time in the X-ray band. The afterglow is not detected in UVOT shortward of the B band, suggesting a redshift of about 3.5. The optical V-band emission lies on the extension of the X-ray spectrum, with an optical-to-X-ray slope of β=-0.8. The relatively flat decay rate of the burst suggests that the central engine continues to inject energy into the fireball for as long as a few × 104 s after the burst.

  16. Does sarcopenia predict change in mobility after hip fracture? a multicenter observational study with one-year follow-up.

    Science.gov (United States)

    Steihaug, Ole Martin; Gjesdal, Clara Gram; Bogen, Bård; Kristoffersen, Målfrid Holen; Lien, Gunhild; Hufthammer, Karl Ove; Ranhoff, Anette Hylen

    2018-03-05

    Patients with hip fracture frequently have sarcopenia and are at great risk of loss of mobility. We have investigated if sarcopenia predicts change in mobility after hip fracture. This is a prospective, multicenter observational study with one-year follow-up. Patients with hip fracture who were community-living and capable of walking before the fracture were included at three hospitals in Norway (2011-2013). The primary outcome of the study was change in mobility, measured by the New Mobility Score (NMS). Sarcopenia was determined postoperatively by anthropometry, grip strength, and NMS. We included 282 participants and sarcopenia status was determined in 201, of whom 38% (77/201) had sarcopenia, 66% (128/194) had low muscle mass, 52% (116/222) had low grip strength and 8% (20/244) had low pre-fracture mobility (NMS mobility (effect 0.2 points; 95% CI -0.5 to 0.9, P = 0.6), but it was associated with having lower mobility at one-year (NMS 5.8 (SD 2.3) vs. 6.8 (SD 2.2), P = 0.003), becoming a resident of a nursing home (odds ratio 3.2, 95% CI 0.9 to 12.4, P = 0.048), and the combined endpoint of becoming a resident of a skilled nursing home or death (odds ratio 3.6, 95% CI 1.2 to 12.2, P = 0.02). Sarcopenia did not predict change in mobility in the year after hip fracture.

  17. Swift X-Ray Telescope Timing Observations of the Black Hole Binary SWIFT J1753.5-0127: Disk-diluted Fluctuations in the Outburst Peak

    NARCIS (Netherlands)

    Kalamkar, M.; van der Klis, M.; Uttley, P.; Altamirano, D.; Wijnands, R.

    2013-01-01

    After a careful analysis of the instrumental effects on the Poisson noise to demonstrate the feasibility of detailed stochastic variability studies with the Swift X-Ray Telescope (XRT), we analyze the variability of the black hole X-ray binary SWIFT J1753.5-0127 in all XRT observations during

  18. Search for neutrinos from transient sources with the ANTARES telescope and optical follow-up observations (TAToO)

    International Nuclear Information System (INIS)

    Dornic, Damien; Brunner, Jurgen; Basa, Stephane; Al Samarai, Imen; Bertin, Vincent; Boer, Michel; Busto, Jose; Escoffier, Stephanie; Klotz, Alain; Mazure, Alain; Vallage, Bertrand

    2011-01-01

    The ANTARES telescope has the opportunity to detect transient neutrino sources, such as gamma-ray bursts, core-collapse supernovae, flares of active galactic nuclei. In order to enhance the sensitivity to these sources, we have developed a new detection method based on the follow-up by optical telescopes of 'golden' neutrino events, such as neutrino doublets coincident in time and space or single neutrinos of very high energy. The ANTARES collaboration has therefore implemented a very fast on-line reconstruction with a good angular resolution. These characteristics allow us to trigger an optical telescope network. Since February 2009, ANTARES is sending alert triggers once or twice per month to the two 25 cm robotic telescope of TAROT. This optical follow-up of such special events would not only give access to the nature of the sources, but also would improve the sensitivity to transient neutrino sources.

  19. RXTE PCA and Swift BAT detects the millisecond pulsar Swift J1756.9-2508 in outburst

    NARCIS (Netherlands)

    Patruno, A.; Markwardt, C.B.; Strohmayer, T.E.; Swank, J.H.; Smith, S.E.; Pereira, D.

    2009-01-01

    We report a detection of increased activity of the accreting millisecond X-ray pulsar Swift J1756.9-2508 observed with the RXTE-PCA monitoring on July 8, 9hr UTC. Increased flux is detected simultaneously on the Swift-BAT camera. RXTE-PCA follow up observations starting on July 13, 23hr UTC,

  20. 'Real-world' atrial fibrillation management in Europe: observations from the 2-year follow-up of the EURObservational Research Programme-Atrial Fibrillation General Registry Pilot Phase.

    Science.gov (United States)

    Proietti, Marco; Laroche, Cécile; Opolski, Grzegorz; Maggioni, Aldo P; Boriani, Giuseppe; Lip, Gregory Y H

    2017-05-01

    Atrial fibrillation (AF) is commonly associated with a high risk of stroke, thromboembolism, and mortality. The 1-year follow-up of the EURObservational Research Programme-Atrial Fibrillation (EORP-AF) Pilot Registry demonstrated a high mortality but good outcomes with European Society of Cardiology guideline-adherent therapy. Whether these 'real-world' observations on patients managed by European cardiologists extend to 2 years remains uncertain. In this report from the EORP-AF General Registry Pilot Phase, we provide data on the 2-year follow-up outcomes. Consistent with the 1-year follow-up report, only a small proportion of patients were symptomatic (24.9%), with minor differences between the different AF subtypes. Persistence of oral anticoagulant (OAC) therapy remains high at 2-years, with ∼80% of patients treated with OAC. The prescribing rates of non-vitamin K antagonist oral anticoagulants are progressively increasing (13.7% at 2 years). Rate and rhythm control approaches remained consistent across the entire follow-up observation. Overall mortality rates remained high, with 5.0% of patients dead during the 2-year follow-up, mostly due to cardiovascular causes (61.8%). Atrial fibrillation readmissions were frequent, particularly related to arrhythmias and heart failure. On multivariate analyses, any cardiovascular reason for admission rather than AF was significantly associated with increased mortality during the 2-year follow-up. In this 2-year follow-up report from EORP-AF, mortality rates with AF remain high from cardiovascular causes, despite the high prevalent use of OAC. Improved management strategies to reduce major adverse outcomes in AF patients are needed. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  1. Swift and INTEGRAL observations of SAX J1747.0-2853

    DEFF Research Database (Denmark)

    Campana, S.; Chenevez, Jérôme; Kuulkers, E.

    2009-01-01

    #1945), even if the field is crowded and the source might be fainter. We observed SAX J1747.0-2853 with Swift XRT on Mar. 3, 2009 between 09:54 and 22:58 UT for 4.6 ks. The source is well detected with a 0.3-10 keV count rate of (2.2+/-0.1)E-1 c/s. The light curve is consistent with being constant. We...... the Swift team for the quick scheduling of this observation....

  2. OPTICAL SPECTROSCOPIC OBSERVATIONS OF GAMMA-RAY BLAZAR CANDIDATES. IV. RESULTS OF THE 2014 FOLLOW-UP CAMPAIGN

    International Nuclear Information System (INIS)

    Ricci, F.; Massaro, F.; Landoni, M.; D’Abrusco, R.; Milisavljevic, D.; Paggi, A.; Smith, Howard A.; Stern, D.; Masetti, N.; Tosti, G.

    2015-01-01

    The extragalactic γ-ray sky is dominated by the emission arising from blazars, one of the most peculiar classes of radio-loud active galaxies. Since the launch of Fermi several methods were developed to search for blazars as potential counterparts of unidentified γ-ray sources (UGSs). To confirm the nature of the selected candidates, optical spectroscopic observations are necessary. In 2013 we started a spectroscopic campaign to investigate γ-ray blazar candidates selected according to different procedures. The main goals of our campaign are: (1) to confirm the nature of these candidates, and (2) whenever possible, determine their redshifts. Optical spectroscopic observations will also permit us to verify the robustness of the proposed associations and check for the presence of possible source class contaminants to our counterpart selection. This paper reports the results of observations carried out in 2014 in the northern hemisphere with Kitt Peak National Observatory and in the southern hemisphere with the Southern Astrophysical Research telescopes. We also report three sources observed with the Magellan and Palomar telescopes. Our selection of blazar-like sources that could be potential counterparts of UGSs is based on their peculiar infrared colors and on their combination with radio observations both at high and low frequencies (i.e., above and below ∼1 GHz) in publicly available large radio surveys. We present the optical spectra of 27 objects. We confirm the blazar-like nature of nine sources that appear to be potential low-energy counterparts of UGSs. Then we present new spectroscopic observations of 10 active galaxies of uncertain type associated with Fermi sources, classifying all of them as blazars. In addition, we present the spectra for five known γ-ray blazars with uncertain redshift estimates and three BL Lac candidates that were observed during our campaign. We also report the case for WISE J173052.85−035247.2, candidate counterpart of the

  3. Hemodialysis Decreases the Etiologically-Related Early Vascular Aging Observed in End-Stage Renal Disease: A 5-Year Follow-Up Study.

    Science.gov (United States)

    Bia, Daniel; Galli, Cintia; Zócalo, Yanina; Valtuille, Rodolfo; Wray, Sandra; Armentano, Ricardo; Cabrera-Fischer, Edmundo

    2017-01-01

    To analyze the early vascular aging (EVA) in end-stage renal disease (ESRD) patients, attempting to determine a potential association between EVA and the etiology of ESRD, and to investigate the association of hemodialysis and EVA in ESRD patients during a 5-year follow-up period. Carotid-femoral pulse wave velocity (cfPWV) was obtained in 151 chronically hemodialyzed patients (CHP) and 283 control subjects, and in 25 CHP, who were followed-up after a 5-year lapse. cfPWV increased in ESRD patients compared to control subjects. The cfPWV-age relationship was found to have a steeper increase in ESRD patients. The highest cfPWV and EVA values were observed in patients with diabetic nephropathy. Regression analysis demonstrated a significant reduction of the EVA in HD patients on a 5-year follow-up. Patients in ESRD showed higher levels of EVA. cfPWV and EVA differed in ESRD patients depending on their renal failure etiology. CHP showed an EVA reduction after a 5-year follow-up period. © 2016 S. Karger AG, Basel.

  4. Ten-Year Follow-up on Tumor Growth and Hearing in Patients Observed With an Intracanalicular Vestibular Schwannoma

    DEFF Research Database (Denmark)

    Kirchmann, Malene; Karnov, Kirstine; Hansen, Søren

    2017-01-01

    . Serviceable hearing was preserved in 34% according to AAO-HNS (class A-B) and in 58% according to the word recognition score (class I-II). Rate of hearing loss was higher in patients with growing tumors.  CONCLUSION: Tumor growth occurred in only a minority of patients diagnosed with an intracanalicular VS...... during 10 years of observation. The risk of hearing loss is small in patients with normal discrimination at diagnosis. Serviceable hearing is preserved spontaneously in 34% according to AAO-HNS and in 58% according to the word recognition score. ...

  5. Long-term follow-up observation of patients with chronic radiation sickness due to external irradiation treated with thymopeptide

    International Nuclear Information System (INIS)

    Gao Shenyong; Sun Wenji; Zhang Aizhen; Ye Anfang

    1998-01-01

    Objective: To provide the clinical data and prognosis judgement, the authors observed the results and progression of 11 cases of chronic radiation sickness due to external irradiation treated with thymopeptide. Methods: The clinical symptoms, hematopoiesis, T lymphocyte percentage and chromosome aberration rate were used as the judgement indexes for recovery from the chronic radiation sickness. Results: Thymopeptide treatment greatly improved the neurasthenic syndrome and increased the T lymphocyte percentage (P 0.05), and improvement of neurasthenic syndrome occurred 3.5 years after they left radiation work or diminished the exposure level. 5 to 8 years after, bone marrow hematopoiesis also restored to the normal level. However, the chromosome aberration rate restored to the normal level 10 years after. Conclusion: According to the judgement criteria, the chronic radiation sickness due to external radiation exposure can recover and thymopeptide is a helpful and simple means to treat it

  6. Directly Observed Therapy Reduces Tuberculosis-Specific Mortality: A Population-Based Follow-Up Study in Taipei, Taiwan

    Science.gov (United States)

    Yen, Yung-Feng; Yen, Muh-Yong; Lin, Yi-Ping; Shih, Hsiu-Chen; Li, Lan-Huei; Chou, Pesus; Deng, Chung-Yeh

    2013-01-01

    Objectives To determine the effect of directly observed therapy (DOT) on tuberculosis-specific mortality and non-TB-specific mortality and identify prognostic factors associated with mortality among adults with culture-positive pulmonary TB (PTB). Methods All adult Taiwanese with PTB in Taipei, Taiwan were included in a retrospective cohort study in 2006–2010. Backward stepwise multinomial logistic regression was used to identify risk factors associated with each mortality outcome. Results Mean age of the 3,487 patients was 64.2 years and 70.4% were male. Among 2471 patients on DOT, 4.2% (105) died of TB-specific causes and 15.4% (381) died of non-TB-specific causes. Among 1016 patients on SAT, 4.4% (45) died of TB-specific causes and 11.8% (120) died of non-TB-specific causes. , After adjustment for potential confounders, the odds ratio for TB-specific mortality was 0.45 (95% CI: 0.30–0.69) among patients treated with DOT as compared with those on self-administered treatment. Independent predictors of TB-specific and non-TB-specific mortality included older age (ie, 65–79 and ≥80 years vs. 18–49 years), being unemployed, a positive sputum smear for acid-fast bacilli, and TB notification from a general ward or intensive care unit (reference: outpatient services). Male sex, end-stage renal disease requiring dialysis, malignancy, and pleural effusion on chest radiography were associated with increased risk of non-TB-specific mortality, while presence of lung cavities on chest radiography was associated with lower risk. Conclusions DOT reduced TB-specific mortality by 55% among patients with PTB, after controlling for confounders. DOT should be given to all TB patients to further reduce TB-specific mortality. PMID:24278152

  7. Follow-Up Testing

    Science.gov (United States)

    ... second should occur after 1 year on the gluten-free diet. After that, a celiac should receive follow-up ... test result is straightforward—a celiac on the gluten-free diet should have a negative test. The numerical value ...

  8. CONTRACT FOLLOW UP TRAINING

    CERN Multimedia

    Technical Training; Tel. 74460

    2001-01-01

    SPL is organizing Training Sessions on the Contract Follow Up application. CFU is a Web based tool, developped and supported by the Administrative Information Services. It allows the creation of Divisional Requests and the follow up of their processing, from the Market Survey to the Invitation to Tender or Price Enquiry, approval by the Finance Committee, up to the actual signature of a Contract, acccording to the CERN Purchasing procedures. It includes a document management component. It also provides link with other AIS applications such as BHT and EDH. The course is primarily intended for DPOs, Contract Technical responsibles in the division and their assistants, but is beneficial to anybody involved in the follow up of such Purchasing Procedures. This course is free of charge, but application is necessary. The details of the course may be found at http://training.web.cern.ch/Training/ENSTEC/P2001/Bureautique/cfu4_f.htm General information of CFU may be found at http://ais.cern.ch/apps/cfu/ The dates of t...

  9. Continuous evidence of fast HIV disease progression related to class-wide resistance to antiretroviral drugs: a 6 year follow-up analysis of a large observational database.

    Science.gov (United States)

    Mauro, Zaccarelli; Federica, Forbici; Patrizia, Lorenzini; Francesca, Ceccherini-Silberstein; Valerio, Tozzi; Paola, Trotta Maria; Patrizia, Marconi; Pasquale, Narciso; Federico, Perno Carlo; Andrea, Antinori

    2007-08-20

    Class-wide resistance (CWR) was increasingly associated with a higher risk of HIV progression after 72 months of follow-up among 1392 patients genotypic-tested after failure (AIDS risk 13% for no CWR to 34% for three CWR; AIDS/death risk 21-54%). At multivariate analysis, the detection of two and three CWR was significantly associated with a two and threefold increased risk, respectively, of death and AIDS/death, suggesting that extended resistance is a marker of disease progression in long-term observation.

  10. INTEGRAL observation of the Galactic transient Swift J174510.8-262411

    DEFF Research Database (Denmark)

    Vovk, I.; Ferrigno, C.; Bozzo, E.

    2012-01-01

    is consistent with the newly discovered transient Swift J174510.8-262411 (GCN #13774, GCN #13775, ATEL #4380). The average broad band 5-500 keV JEM-X (61.6 ks) plus IBIS/ISGRI (63.9 ks) spectrum can be well fit by a power-law with exponential cut-off at high energy: Γ=1.29±0.04, Ecut=(122±10) keV (χ2=0.9 for 19...... with time. On the base of the rapid flux increase, the high value of the energy cut-off and the absence of thermonuclear bursts, we argue that Swift J174510.8-262411 might be a new black-hole transient. Further observations at all wavelengths are encouraged to unveil the nature of this source. We thank...

  11. An observational study of autologous bone marrow-derived stem cells transplantation in seven patients with nervous system diseases: a 2-year follow-up.

    Science.gov (United States)

    Ren, Chao; Geng, Run-lu; Ge, Wei; Liu, Xiao-Yun; Chen, Hao; Wan, Mei-Rong; Geng, De-Qin

    2014-05-01

    Currently, autologous bone marrow-derived stem cell is one of the most innovative areas of stem cells research. Previous studies on animal models of nervous system diseases have shown that these cells have a good effect on nervous system disorders. The alternative treatment with stem cells for the nervous system diseases has also gradually reached to clinical application stage. The prospect is captivating, but the safety and efficacy of this procedure need further research. To observe the clinical efficacy and side effects of the treatment for autologous mesenchymal stem cells and neural stem/progenitor cells which are in differentiated form by inducing with cerebrospinal fluid in the patients with nervous system diseases, thirty patients were selected from our hospital (2009-10 to 2012-07) and were followed at 1 month, 3 months, 6 months, 1 year and 2 years after the treatment with autologous mesenchymal stem cells and neural stem/progenitor cells in differentiated form was introduced. In this paper, we will introduce the process to make cells accessible for the clinical application by the description of the changes observed in 7 cases were followed for 2 years. The time for bone marrow mesenchymal stem cells could be available for clinical needs is as early as 5 days, not later than 10 days, and the median time is 8 days, while neural stem/progenitor cells in differentiated form can be available for clinical needs in as early as 12 days, not later than 15 days, and the median time is 13.5 days (statistical explanation: Case 5 only uses autologous mesenchymal stem cells, and Case 7 has two times bone marrow punctures). The neurological function of the patients was improved in 1-month follow-up, and the patients have a better discontinuous trend (statistical explanation: sometimes the neurological function of the patients between two adjacent follow-ups does not change significantly). After transplantation, four patients appeared to have transient fever, but it was

  12. Deep NuSTAR and Swift monitoring observations of the magnetar 1E 1841-045

    DEFF Research Database (Denmark)

    An, Hongjun; Archibald, Robert F.; Hascoët, Romain

    2015-01-01

    We report on a 350 ks NuSTAR observation of the magnetar 1E 1841-045 taken in 2013 September. During the observation, NuSTAR detected six bursts of short duration, with T90 ≲ 1 s. An elevated level of emission tail is detected after the brightest burst, persisting for ~1 ks. The emission showed a...... consistent with the footprint of the twisted magnetic field lines on the star. We also report on the 3 yr Swift monitoring observations obtained since 2011 July. The soft-X-ray spectrum remained stable during this period, and the timing behavior was noisy, with large timing residuals....

  13. A one-year observational study of all hospitalized and fatal acute poisonings in Oslo: epidemiology, intention and follow-up.

    Science.gov (United States)

    Lund, Cathrine; Teige, Brita; Drottning, Per; Stiksrud, Birgitte; Rui, Tor Olav; Lyngra, Marianne; Ekeberg, Oivind; Jacobsen, Dag; Hovda, Knut Erik

    2012-10-09

    Up to date information on poisoning trends is important. This study reports the epidemiology of all hospitalized acute poisonings in Oslo, including mortality, follow-up referrals, and whether the introduction of over-the-counter sales of paracetamol outside pharmacies had an impact on the frequency of poisonings. All acute poisonings of adults (≥16 years) treated at the five hospitals in Oslo from April 2008 to April 2009 were included consecutively in an observational cross-sectional multicentre study. A standardized form was completed by the treating physician, which covered the study aims. All deaths by poisoning in and outside hospitals were registered at the Institute of Forensic Medicine. There were 1065 hospital admissions of 912 individuals; 460 (50%) were male, and the median age was 36 years. The annual incidence was 2.0 per 1000. The most frequent toxic agents were ethanol (18%), benzodiazepines (15%), paracetamol (11%), and opioids (11%). Physicians classified 46% as possible or definite suicide attempts, 37% as accidental overdoses with substances of abuse (AOSA), and 16% as other accidents. Twenty-four per cent were discharged without any follow-up and the no follow-up odds were highest for AOSA. There were 117 deaths (eight in hospital), of which 75% were males, and the median age was 41 years. Thus, the annual mortality rate was 25 per 100 000 and the in-hospital mortality was 0.8%. Opioids were the most frequent cause of death. The incidence of hospitalized acute poisonings in Oslo was similar to that in 2003 and there was an equal sex distribution. Compared with a study performed in Oslo in 2003, there has been an increase in poisonings with a suicidal intention. The in-hospital mortality was low and nine out of ten deaths occurred outside hospitals. Opioids were the leading cause of death, so preventive measures should be encouraged among substance abusers. The number of poisonings caused by paracetamol remained unchanged after the

  14. Newborn follow-up after discharge from a tertiary care hospital in the Western Cape region of South Africa: a prospective observational cohort study.

    Science.gov (United States)

    Milambo, Jean Paul Muambangu; Cho, KaWing; Okwundu, Charles; Olowoyeye, Abiola; Ndayisaba, Leonidas; Chand, Sanjay; Corden, Mark H

    2018-01-01

    Current practice in the Western Cape region of South Africa is to discharge newborns born in-hospital within 24 h following uncomplicated vaginal delivery and two days after caesarean section. Mothers are instructed to bring their newborn to a clinic after discharge for a health assessment. We sought to determine the rate of newborn follow-up visits and the potential barriers to timely follow-up. Mother-newborn dyads at Tygerberg Hospital in Cape Town, South Africa were enrolled from November 2014 to April 2015. Demographic data were obtained via questionnaire and medical records. Mothers were contacted one week after discharge to determine if they had brought their newborns for a follow-up visit, and if not, the barriers to follow-up. Factors associated with follow-up were analyzed using logistic regression. Of 972 newborns, 794 (82%) were seen at a clinic for a follow-up visit within one week of discharge. Mothers with a higher education level or whose newborns were less than 37 weeks were more likely to follow up. The follow-up rate did not differ based on hospital length of stay. Main reported barriers to follow-up included maternal illness, lack of money for transportation, and mother felt follow-up was unnecessary because newborn was healthy. Nearly 4 in 5 newborns were seen at a clinic within one week after hospital discharge, in keeping with local practice guidelines. Further research on the outcomes of this population and those who fail to follow up is needed to determine the impact of postnatal healthcare policy.

  15. Optical Follow-Up Observations of PTF10qts, a Luminous Broad-Lined Type Ic Supernova Found by the Palomar Transient Factory

    Science.gov (United States)

    Walker, E. S.; Mazzali, P. A.; Pian, E.; Hurley, K.; Arcavi, I.; Cenko, S. B.; Gal-Yam, A.; Horesh, A.; Kasliwal, M.; Poznanski, D.; hide

    2014-01-01

    We present optical photometry and spectroscopy of the broad-lined Type Ic supernova (SN Ic-BL) PTF10qts, which was discovered as part of the Palomar Transient Factory. The supernova was located in a dwarf galaxy of magnitude r = 21.1 at a redshift z = 0.0907.We find that the R-band light curve is a poor proxy for bolometric data and use photometric and spectroscopic data to construct and constrain the bolometric light curve. The derived bolometric magnitude at maximum light is Mbol = -18.51 +/- 0.2 mag, comparable to that of SN1998bw (Mbol = -18.7 mag) which was associated with a gamma-ray burst (GRB). PTF10qts is one of the most luminous SN Ic-BL observed without an accompanying GRB. We estimate the physical parameters of the explosion using data from our programme of follow-up observations, finding that it produced a larger mass of radioactive nickel compared to other SNeIc-BL with similar inferred ejecta masses and kinetic energies. The progenitor of the event was likely a approximately 20 solar mass star.

  16. Swift and Fermi Observations of X-Ray Flares: The Case of Late Internal Shock

    Science.gov (United States)

    Troja, E.; Piro, L.; Vasileiou, V.; Omodei, N.; Burgess, J. M.; Cutini, S.; Connaughton, V.; McEnery, J. E.

    2015-01-01

    Simultaneous Swift and Fermi observations of gamma-ray bursts (GRBs) offer a unique broadband view of their afterglow emission, spanning more than 10 decades in energy. We present the sample of X-ray flares observed by both Swift and Fermi during the first three years of Fermi operations. While bright in the X-ray band, X-ray flares are often undetected at lower (optical), and higher (MeV to GeV) energies. We show that this disfavors synchrotron self-Compton processes as the origin of the observed X-ray emission. We compare the broadband properties of X-ray flares with the standard late internal shock model, and find that in this scenario, X-ray flares can be produced by a late-time relativistic (gamma greater than 50) outflow at radii R approximately 10(exp 13) - 10(exp 14) cm. This conclusion holds only if the variability timescale is significantly shorter than the observed flare duration, and implies that X-ray flares can directly probe the activity of the GRB central engine.

  17. Influence of Anti-TNF and Disease Modifying Antirheumatic Drugs Therapy on Pulmonary Forced Vital Capacity Associated to Ankylosing Spondylitis: A 2-Year Follow-Up Observational Study

    Directory of Open Access Journals (Sweden)

    Alberto Daniel Rocha-Muñoz

    2015-01-01

    Full Text Available Objective. To evaluate the effect of anti-TNF agents plus synthetic disease modifying antirheumatic drugs (DMARDs versus DMARDs alone for ankylosing spondylitis (AS with reduced pulmonary function vital capacity (FVC%. Methods. In an observational study, we included AS who had FVC% <80% at baseline. Twenty patients were taking DMARDs and 16 received anti-TNF + DMARDs. Outcome measures: changes in FVC%, BASDAI, BASFI, 6-minute walk test (6MWT, Borg scale after 6MWT, and St. George’s Respiratory Questionnaire at 24 months. Results. Both DMARDs and anti-TNF + DMARDs groups had similar baseline values in FVC%. Significant improvement was achieved with anti-TNF + DMARDs in FVC%, at 24 months, when compared to DMARDs alone (P=0.04. Similarly, patients in anti-TNF + DMARDs group had greater improvement in BASDAI, BASFI, Borg scale, and 6MWT when compared to DMARDs alone. After 2 years of follow-up, 14/16 (87.5% in the anti-TNF + DMARDs group achieved the primary outcome: FVC% ≥80%, compared with 11/20 (55% in the DMARDs group (P=0.04. Conclusions. Patients with anti-TNF + DMARDs had a greater improvement in FVC% and cardiopulmonary scales at 24 months compared with DMARDs. This preliminary study supports the fact that anti-TNF agents may offer additional benefits compared to DMARDs in patients with AS who have reduced FVC%.

  18. GRBs in the Era of Swift and Fermi

    Science.gov (United States)

    Racusin, Judy

    2011-01-01

    Utilizing both Swift and Fermi to study GRBs provides us with a unique broad spectral and temporal window into both prompt emission and afterglow studies. Swift has provided key information from GRB follow-up of LAT detected bursts) that has led to ground-based redshift measurements and afterglow broadband light curves and SEDs. We study the X-ray and optical afterglows of Fermi-LAT detected bursts in the context of the hundreds of GRBs discovered by Swift over the last 7 years) in order to better understand the origin of the high-energy gamma-rays. We also briefly describe the efforts to best facilitate joint Swift-Fermi observations. These initial results demonstrate the synergy between Swift and Fermi) and hint at the many interesting discoveries to come.

  19. TESS Follow-up Observing Program (TFOP) Working Group:A Mission-led Effort to Coordinate Community Resources to Confirm TESS Planets

    Science.gov (United States)

    Collins, Karen; Quinn, Samuel N.; Latham, David W.; Christiansen, Jessie; Ciardi, David; Dragomir, Diana; Crossfield, Ian; Seager, Sara

    2018-01-01

    The Transiting Exoplanet Survey Satellite (TESS) will observe most of the sky over a period of two years. Observations will be conducted in 26 sectors of sky coverage and each sector will be observed for ~27 days. Data from each sector is expected to produce hundreds of transiting planet candidates (PCs) per month and thousands over the two year nominal mission. The TFOP Working Group (WG) is a mission-led effort organized to efficiently provide follow-up observations to confirm candidates as planets or reject them as false positives. The primary goal of the TFOP WG is to facilitate achievement of the Level One Science Requirement to measure masses for 50 transiting planets smaller than 4 Earth radii. Secondary goals are to serve any science coming out of TESS and to foster communication and coordination both within the TESS Science Team and with the community at large. The TFOP WG is organized as five Sub Groups (SGs). SG1 will provide seeing-limited imaging to measure blending within a candidate's aperture and time-series photometry to identify false positives and in some cases to improve ephemerides, light curves, and/or transit time variation (TTV) measurements. SG2 will provide reconnaissance spectroscopy to identify astrophysical false positives and to contribute to improved host star parameters. SG3 will provide high-resolution imaging with adaptive optics, speckle imaging, and lucky imaging to detect nearby objects. SG4 will provide precise radial velocities to derive orbits of planet(s) and measure their mass(es) relative to the host star. SG5 will provide space-based photometry to confirm and/or improve the TESS photometric ephemerides, and will also provide improved light curves for transit events or TTV measurements. We describe the TFOP WG observing and planet confirmation process, the five SGs that comprise the TFOP WG, ExoFOP-TESS and other web-based tools being developed to support TFOP WG observers, other advantages of joining the TFOP WG, the TFOP

  20. Ultraviolet, Optical, and X-Ray Observations of the Type Ia Supernova 2005am with Swift

    Science.gov (United States)

    Brown, P. J.; Holland, S. T.; James, C.; Milne, P.; Roming, P. W. A.; Mason, K. O.; Page, K. L.; Beardmore, A. P.; Burrows, D.; Morgan, A.; Gronwall, C.; Blustin, A. J.; Boyd, P.; Still, M.; Breeveld, A.; de Pasquale, M.; Hunsberger, S.; Ivanushkina, M.; Landsman, W.; McGowan, K.; Poole, T.; Rosen, S.; Schady, P.; Gehrels, N.

    2005-12-01

    We present ultraviolet and optical light curves in six broadband filters and grism spectra obtained by Swift's Ultraviolet/Optical Telescope for the Type Ia supernova SN 2005am. The data were collected beginning about 4 days before the B-band maximum, with excellent coverage of the rapid decline phase and later observations extending out to 69 days after the peak. The optical and near-UV light curve match well those of SN 1992A. The other UV observations constitute the first set of light curves shorter than 2500 Å and allow us to compare the light curve evolution in three UV bands. One interesting feature is that the decay in the intermediate UVM2 band is shallower than in the filters on either side and may result from the bump in the interstellar extinction curve. The UV behavior of this and other low-redshift supernovae can be used to constrain theories of progenitor evolution or to interpret optical light curves of high-redshift supernovae. Using Swift's X-Ray Telescope, we also report the upper limit to SN 2005am's X-ray luminosity to be 6×1039 ergs s-1 in the 0.3-10 keV. This result is derived from 58 ks of exposure time spread out over 7 weeks beginning 4 days before the B-band maximum.

  1. Multiwavelength follow-up of a rare IceCube neutrino multiplet

    Science.gov (United States)

    Icecube Collaboration; Aartsen, M. G.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Al Samarai, I.; Altmann, D.; Andeen, K.; Anderson, T.; Ansseau, I.; Anton, G.; Archinger, M.; Argüelles, C.; Auffenberg, J.; Axani, S.; Bai, X.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Tjus, J. Becker; Becker, K.-H.; Benzvi, S.; Berley, D.; Bernardini, E.; Bernhard, A.; Besson, D. Z.; Binder, G.; Bindig, D.; Blaufuss, E.; Blot, S.; Bohm, C.; Börner, M.; Bos, F.; Bose, D.; Böser, S.; Botner, O.; Braun, J.; Brayeur, L.; Bretz, H.-P.; Bron, S.; Burgman, A.; Carver, T.; Casier, M.; Cheung, E.; Chirkin, D.; Christov, A.; Clark, K.; Classen, L.; Coenders, S.; Collin, G. H.; Conrad, J. M.; Cowen, D. F.; Cross, R.; Day, M.; de André, J. P. A. M.; de Clercq, C.; Del Pino Rosendo, E.; Dembinski, H.; De Ridder, S.; Desiati, P.; de Vries, K. D.; de Wasseige, G.; de With, M.; Deyoung, T.; di Lorenzo, V.; Dujmovic, H.; Dumm, J. P.; Dunkman, M.; Eberhardt, B.; Ehrhardt, T.; Eichmann, B.; Eller, P.; Euler, S.; Evenson, P. A.; Fahey, S.; Fazely, A. R.; Feintzeig, J.; Felde, J.; Filimonov, K.; Finley, C.; Flis, S.; Fösig, C.-C.; Franckowiak, A.; Friedman, E.; Fuchs, T.; Gaisser, T. K.; Gallagher, J.; Gerhardt, L.; Ghorbani, K.; Giang, W.; Gladstone, L.; Glauch, T.; Glüsenkamp, T.; Goldschmidt, A.; Gonzalez, J. G.; Grant, D.; Griffith, Z.; Haack, C.; Hallgren, A.; Halzen, F.; Hansen, E.; Hansmann, T.; Hanson, K.; Hebecker, D.; Heereman, D.; Helbing, K.; Hellauer, R.; Hickford, S.; Hignight, J.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Hoshina, K.; Huang, F.; Huber, M.; Hultqvist, K.; in, S.; Ishihara, A.; Jacobi, E.; Japaridze, G. S.; Jeong, M.; Jero, K.; Jones, B. J. P.; Kang, W.; Kappes, A.; Karg, T.; Karle, A.; Katz, U.; Kauer, M.; Keivani, A.; Kelley, J. L.; Kheirandish, A.; Kim, J.; Kim, M.; Kintscher, T.; Kiryluk, J.; Kittler, T.; Klein, S. R.; Kohnen, G.; Koirala, R.; Kolanoski, H.; Konietz, R.; Köpke, L.; Kopper, C.; Kopper, S.; Koskinen, D. J.; Kowalski, M.; Krings, K.; Kroll, M.; Krückl, G.; Krüger, C.; Kunnen, J.; Kunwar, S.; Kurahashi, N.; Kuwabara, T.; Kyriacou, A.; Labare, M.; Lanfranchi, J. L.; Larson, M. J.; Lauber, F.; Lesiak-Bzdak, M.; Leuermann, M.; Lu, L.; Lünemann, J.; Madsen, J.; Maggi, G.; Mahn, K. B. M.; Mancina, S.; Mandelartz, M.; Maruyama, R.; Mase, K.; Maunu, R.; McNally, F.; Meagher, K.; Medici, M.; Meier, M.; Menne, T.; Merino, G.; Meures, T.; Miarecki, S.; Micallef, J.; Momenté, G.; Montaruli, T.; Moulai, M.; Nahnhauer, R.; Naumann, U.; Neer, G.; Niederhausen, H.; Nowicki, S. C.; Nygren, D. R.; Obertacke Pollmann, A.; Olivas, A.; O'Murchadha, A.; Palczewski, T.; Pandya, H.; Pankova, D. V.; Peiffer, P.; Penek, Ö.; Pepper, J. A.; Pérez de Los Heros, C.; Pieloth, D.; Pinat, E.; Price, P. B.; Przybylski, G. T.; Quinnan, M.; Raab, C.; Rädel, L.; Rameez, M.; Rawlins, K.; Reimann, R.; Relethford, B.; Relich, M.; Resconi, E.; Rhode, W.; Richman, M.; Riedel, B.; Robertson, S.; Rongen, M.; Rott, C.; Ruhe, T.; Ryckbosch, D.; Rysewyk, D.; Sabbatini, L.; Sanchez Herrera, S. E.; Sandrock, A.; Sandroos, J.; Sarkar, S.; Satalecka, K.; Schlunder, P.; Schmidt, T.; Schoenen, S.; Schöneberg, S.; Schumacher, L.; Seckel, D.; Seunarine, S.; Soldin, D.; Song, M.; Spiczak, G. M.; Spiering, C.; Stachurska, J.; Stanev, T.; Stasik, A.; Stettner, J.; Steuer, A.; Stezelberger, T.; Stokstad, R. G.; Stößl, A.; Ström, R.; Strotjohann, N. L.; Sullivan, G. W.; Sutherland, M.; Taavola, H.; Taboada, I.; Tatar, J.; Tenholt, F.; Ter-Antonyan, S.; Terliuk, A.; Tešić, G.; Tilav, S.; Toale, P. A.; Tobin, M. N.; Toscano, S.; Tosi, D.; Tselengidou, M.; Tung, C. F.; Turcati, A.; Unger, E.; Usner, M.; Vandenbroucke, J.; van Eijndhoven, N.; Vanheule, S.; van Rossem, M.; van Santen, J.; Vehring, M.; Voge, M.; Vogel, E.; Vraeghe, M.; Walck, C.; Wallace, A.; Wallraff, M.; Wandkowsky, N.; Waza, A.; Weaver, Ch.; Weiss, M. J.; Wendt, C.; Westerhoff, S.; Whelan, B. J.; Wickmann, S.; Wiebe, K.; Wiebusch, C. H.; Wille, L.; Williams, D. R.; Wills, L.; Wolf, M.; Wood, T. R.; Woolsey, E.; Woschnagg, K.; Xu, D. L.; Xu, X. W.; Xu, Y.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Zoll, M.; Asas-Sn Collaboration; Stanek, K. Z.; Shappee, B. J.; Kochanek, C. S.; Holoien, T. W.-S.; Prieto, J. L.; Astrophysical Multimessenger Observatory Network; Fox, D. B.; Delaunay, J. J.; Turley, C. F.; Barthelmy, S. D.; Lien, A. Y.; Mészáros, P.; Murase, K.; Fermi Collaboration; Kocevski, D.; Buehler, R.; Giomi, M.; Racusin, J. L.; Hawc Collaboration; Albert, A.; Alfaro, R.; Alvarez, C.; Álvarez, J. D.; Arceo, R.; Arteaga-Velázquez, J. C.; Ayala Solares, H. A.; Barber, A. S.; Baustista-Elivar, N.; Becerril, A.; Belmont-Moreno, E.; Bernal, A.; Brisbois, C.; Caballero-Mora, K. S.; Capistrán, T.; Carramiñana, A.; Casanova, S.

    2017-11-01

    On February 17, 2016, the IceCube real-time neutrino search identified, for the first time, three muon neutrino candidates arriving within 100 s of one another, consistent with coming from the same point in the sky. Such a triplet is expected once every 13.7 years as a random coincidence of background events. However, considering the lifetime of the follow-up program the probability of detecting at least one triplet from atmospheric background is 32%. Follow-up observatories were notified in order to search for an electromagnetic counterpart. Observations were obtained by Swift's X-ray telescope, by ASAS-SN, LCO and MASTER at optical wavelengths, and by VERITAS in the very-high-energy gamma-ray regime. Moreover, the Swift BAT serendipitously observed the location 100 s after the first neutrino was detected, and data from the Fermi LAT and HAWC observatory were analyzed. We present details of the neutrino triplet and the follow-up observations. No likely electromagnetic counterpart was detected, and we discuss the implications of these constraints on candidate neutrino sources such as gamma-ray bursts, core-collapse supernovae and active galactic nucleus flares. This study illustrates the potential of and challenges for future follow-up campaigns.

  2. An observational study on surgically treated adult idiopathic scoliosis patients' quality of life outcomes at 1- and 2-year follow-ups and comparison to controls.

    Science.gov (United States)

    Theis, Jennifer C; Grauers, Anna; Diarbakerli, Elias; Savvides, Panayiotis; Abbott, Allan; Gerdhem, Paul

    2017-01-01

    Prospective data on health-related quality of life in patients with idiopathic scoliosis treated surgically as adults is needed. We compared preoperative and 1- and 2-year follow-up data in surgically treated adults with idiopathic scoliosis with juvenile or adolescent onset. Results were compared to untreated adults with scoliosis and population normative data. A comparison of preoperative and 1- and 2-year follow-up data of 75 adults surgically treated for idiopathic scoliosis at a mean age of 28 years (range 18 to 69) from a prospective national register study, as well as a comparison with age- and sex-matched data from 75 untreated adults with less severe scoliosis and 75 adults without scoliosis, was made. Outcome measures were EuroQol-5 dimensions (EQ-5D) and Scoliosis Research Society (SRS)-22r questionnaire. In the surgically treated, EQ-5D and SRS-22r scores had statistically significant improvements at both 1- and 2-year follow-ups (all p   up was large ( r  = -0.54) and small-medium ( r  = -0.20) at 2-year follow-up. The effect size of surgery on SRS-22r outcomes was medium-large at 1- and 2-year follow-ups ( r  = -0.43 and r  = -0.42 respectively). At the 2-year follow-up, the EQ-5D score and the SRS-22r subscore were similar to the untreated scoliosis group ( p  = 0.56 and p  = 0.91 respectively), but lower than those in the adults without scoliosis ( p  up, approaching the health-related quality of life of untreated individuals with less severe scoliosis, but remain lower than normative population data.

  3. The 2005 outburst of GRO J1655-40: spectral evolution of the rise, as observed by Swift

    OpenAIRE

    Brocksopp, C.; McGowan, K. E.; Krimm, H.; Godet, O.; Roming, P.; Mason, K. O.; Gehrels, N.; Still, M.; Page, K.; Moretti, A.; Shrader, C. R.; Campana, S.; Kennea, J.

    2005-01-01

    We present Swift observations of the black hole X-ray transient, GRO J1655-40, during the recent outburst. With its multiwavelength capabilities and flexible scheduling, Swift is extremely well-suited for monitoring the spectral evolution of such an event. GRO J1655-40 was observed on 20 occasions and data were obtained by all instruments for the majority of epochs. X-ray spectroscopy revealed spectral shapes consistent with the ``canonical'' low/hard, high/soft and very high states at variou...

  4. Gamma Ray Burst Discoveries with the Swift Mission

    Science.gov (United States)

    Gehrels, Neil; Tueller, Jack

    2007-01-01

    There is a great synergy between the Swift and INTEGRAL missions. Swift provides wide-field hard x-ray monitoring and sensitive x-ray and UV/optical observations. INTEGRAL provides optical through gamma-ray coverage with emphasis on hard xray imaging and gamma-ray spectroscopy. For hard x-ray survey studies, the BAT and IBIS instruments are complementary with BAT covering the full sky every day and IBIS scanning the galactic plane. For GRBs, Swift follows up bursts detected by INTEGRAL. X-ray and optical observations give arcsecond positions and afterglow lightcurves. For IGR sources, X-ray observations identify counterparts. The joint BAT and IBIS survey data are giving the most complete picture of the hard x-ray sky ever obtained. This talk will review Swift capabilities and discuss joint observations that are taking place and planned

  5. NuSTAR and SWIFT Observations of the Black Hole Candidate XTE J1908+094 during its 2013 Outburst

    DEFF Research Database (Denmark)

    Tao, Lian; Tomsick, John A.; Walton, Dominic J.

    2015-01-01

    The black hole (BH) candidate XTE J1908+094 went into outburst for the first time since 2003 in 2013 October. We report on an observation with the Nuclear Spectroscopic Telescope Array (NuSTAR) and monitoring observations with Swift during the outburst. NuSTAR caught the source in the soft state...

  6. EFFICIENCY OF INFLUENZA VACCINATION IN PATIENTS WITH CIRCULATORY SYSTEM DISEASES UNDER DISPENSARY OBSERVATION IN OUTPATIENT CLINICS: PROSPECTIVE FOLLOW-UP MONITORING DATA

    Directory of Open Access Journals (Sweden)

    S. A. Boytsov

    2016-01-01

    Full Text Available Aim. To estimate an efficiency of influenza vaccination in patients with circulatory system diseases diseases (CSD under 3-year follow-up in outpatient clinics.Methods. The efficiency of influenza vaccination was investigated in CSD patients followed up at 2Ivanovo outpatient clinics and 2Saratov ones. The investigation enrolled 817 people, including 367 patients who consented to Grippol Plus influenza vaccination and 450 who refused.Results. During 36-month follow-up after being included in the study the vaccinated group showed a significantly fewer influenza and acute respiratory viral infections than the non-vaccinated group (28 and 442; р<0.0001. The vaccinated group had fewer CSD worsening cases per patient (p=0.04 and CSD-associated hospitalization rates (p=0.006 than the non-vaccinated group. In the vaccinated group, the total number of cases of cerebral stroke, myocardial infarction, deaths from cardiovascular diseases (CVD was significantly less (17 compared with non-vaccinated (38, р=0.03. The risk of infectious diseases and acute cardiovascular event (myocardial infarction, stroke, death from CVD was significantly lower in the group of vaccinated patients: by 36% (p=0.001 and by 59% (p=0.008, respectively.Conclusion. Influenza vaccination, as an essential component of complex medical prevention, leads to reduction in incidence of infectious diseases and of CSD worsening including myocardial infarction, stroke, and death from CVD in patients under 3-year monitoring in outpatient clinics

  7. Effect of bivalent human papillomavirus vaccination on pregnancy outcomes: long term observational follow-up in the Costa Rica HPV Vaccine Trial.

    Science.gov (United States)

    Panagiotou, Orestis A; Befano, Brian L; Gonzalez, Paula; Rodríguez, Ana Cecilia; Herrero, Rolando; Schiller, John T; Kreimer, Aimée R; Schiffman, Mark; Hildesheim, Allan; Wilcox, Allen J; Wacholder, Sholom

    2015-09-07

    To examine the effect of the bivalent human papillomavirus (HPV) vaccine on miscarriage. Observational long term follow-up of a randomized, double blinded trial combined with an independent unvaccinated population based cohort. Single center study in Costa Rica. 7466 women in the trial and 2836 women in the unvaccinated cohort enrolled at the end of the randomized trial and in parallel with the observational trial component. Women in the trial were assigned to receive three doses of bivalent HPV vaccine (n=3727) or the control hepatitis A vaccine (n=3739). Crossover bivalent HPV vaccination occurred in the hepatitis A vaccine arm at the end of the trial. Women in the unvaccinated cohort received (n=2836) no vaccination. Risk of miscarriage, defined by the US Centers for Disease Control and Prevention as fetal loss within 20 weeks of gestation, in pregnancies exposed to bivalent HPV vaccination in less than 90 days and any time from vaccination compared with pregnancies exposed to hepatitis A vaccine and pregnancies in the unvaccinated cohort. Of 3394 pregnancies conceived at any time since bivalent HPV vaccination, 381 pregnancies were conceived less than 90 days from vaccination. Unexposed pregnancies comprised 2507 pregnancies conceived after hepatitis A vaccination and 720 conceived in the unvaccinated cohort. Miscarriages occurred in 451 (13.3%) of all exposed pregnancies, in 50 (13.1%) of the pregnancies conceived less than 90 days from bivalent HPV vaccination, and in 414 (12.8%) of the unexposed pregnancies, of which 316 (12.6%) were in the hepatitis A vaccine group and 98 (13.6%) in the unvaccinated cohort. The relative risk of miscarriage for pregnancies conceived less than 90 days from vaccination compared with all unexposed pregnancies was 1.02 (95% confidence interval 0.78 to 1.34, one sided P=0.436) in unadjusted analyses. Results were similar after adjusting for age at vaccination (relative risk 1.15, one sided P=0.17), age at conception (1.03, P=0

  8. Long-term follow-up after epilepsy surgery in infancy and early childhood--a prospective population based observational study.

    Science.gov (United States)

    Reinholdson, Jesper; Olsson, Ingrid; Edelvik, Anna; Hallböök, Tove; Lundgren, Johan; Rydenhag, Bertil; Malmgren, Kristina

    2015-08-01

    To describe 2-year and long-term outcomes (five or ten years) after resective epilepsy surgery in children operated before the age of four years. This prospective, population based, longitudinal study is based on data from the Swedish National Epilepsy Surgery Register 1995-2010. The following variables were analysed: seizure frequency, antiepileptic drug treatment (AED), neurological deficits, type of operation, histopathological diagnosis and perioperative complications. During the study period 47 children under four years had resective surgery. A majority had seizure onset within the first year of life, and the median age at surgery was two years and one month. Two thirds had neurodevelopmental abnormalities. Temporal lobe resection, frontal lobe resection and hemispherotomy predominated. A majority had malformations of cortical development. There was one major perioperative complication. At the 2-year follow-up, 21/47 children (45%) were seizure free, eight of whom were off medication. At the long-term follow-up, 16/32 (50%) were seizure-free and 11 of them off medication. Another ten (31%) had ≥75% reduction in seizure frequency. Fourteen children (44%) had sustained seizure freedom from surgery to the long-term follow-up. This is the first prospective, population based, longitudinal study to show that a favourable seizure outcome is achievable in a majority of infants and young children undergoing resective epilepsy surgery and that the improvements are consistent over time. Many can also stop taking AEDs. The findings emphasise the importance of early referral to epilepsy surgery evaluation in cases of medically intractable epilepsy in infants and young children. Copyright © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  9. On the "canonical behaviour" of the X-ray afterglows of the Gamma Ray Bursts observed with Swift's XRT

    CERN Document Server

    Dado, S; De Rújula, Alvaro; Dado, Shlomo; Dar, Arnon

    2006-01-01

    The "canonical behaviour" of the early X-ray afterglows of long-duration Gamma-Ray Bursts (GRBs) --observed by the X-Ray Telescope of the SWIFT satellite-- is precisely the one predicted by the Cannonball model of GRBs.

  10. A Swift Look at SN 2011fe: The Earliest Ultraviolet Observations of a Type Ia Supernova

    Science.gov (United States)

    Oates, Samantha; Holland, Stephen; Immler, Stefan; Brown, Peter J.; Dawson, Kyle S.; DePasquale, Massimiliano; Gronwall, Caryl; Kuin, Paul; Mazzali, Paolo; Miline, Peter; hide

    2012-01-01

    We present the earliest ultraviolet (UV) observations of the bright Type Ia supernova SN 2011fe/PTF11kly in the nearby galaxy M101 at a distance of only 6.4 Mpc. It was discovered shortly after explosion by the Palomar Transient Factory and first observed by Swift/UVOT about a day after explosion. The early UV light is well-defined, with approx. 20 data points per filter in the 5 days after explosion. With these early UV observations, we extend the near-UV template of SNe Ia to earlier times for comparison with observations at low and high redshift and report fits from semiempirical models of the explosion. We find the early UV count rates to be well fit by the superposition of two parabolic curves. Finally, we use the early UV flux measurements to examine a possible shock interaction with a non-degenerate companion. We find that even a solar mass companion at a distance of a few solar radii is unlikely at more than 95% confidence.

  11. Global Properties of X-Ray Flashes and X-Ray-Rich GRBs Observed by Swift

    Science.gov (United States)

    Sakamoto, T.; Yamazaki, R.; Cummings, J.; Krimm, H.; Parsons, A.; Hullinger, D.; Barbier, L.; Fenimore, E.; Markwardt, C.; Tueller, J.; hide

    2007-01-01

    We describe and discuss the spectral and temporal characteristics of the prompt emission and X-ray afterglow emission of X-ray flashes (XRFs) detected and observed by Swift between December 2005 and September 2006. We compare these characteristics to a sample of X-ray rich gamma-ray bursts (XRRs) and conventional classical gamma-ray bursts (C-GRBs)observed during the same period. We confirm the correlation between Epeak and fluence noted by others and find further evidence that XRFs and C-GRBs form a continuum. We also confirmed that our known redshift samples are consistent with the correlation between the peak energy (Epeak) and the isotropic radiated energy (Eiso), so called the Epeak-Eiso relation. The spectral properties of X-ray afterglows are similar to those of gamma-ray burst afterglows, but the temporal properties of the two classes are quite different. We found that the light curves of C-GRBs afterglow show a break to steeper indices (shallow-to-steep break) at much earlier times than do XRF afterglows. Moreover, the overall luminosity of X-ray afterglows of XRFs are systematically smaller by a factor of two or more compared with that of C-GRBs. These distinct differences in the X-ray afterglow between XRFs and C-GRBs are key to understanding not only a mysterious shallow-to-steep phase in the X-ray afterglow but also the unique nature of XRFs.

  12. Rapid Response Astronomy Using the Swift GRB Explorer

    Science.gov (United States)

    Nousek, J. A.; Chester, M. M.; Gehrels, N.; Marshall, F. E.; Swift Team

    2001-12-01

    Swift is a multi-wavelength observatory designed for the autonomous detection and immediate follow-up of gamma-ray bursts and their afterglows. Its Burst Alert Telescope (BAT) will detect 100s of GRBs per year, and the observatory will autonomously train sensitive UV/optical and X-ray telescopes on the burst within 10 to 75 seconds. GRB and X-ray positions and a UV/optical finding chart will be rapidly distributed through the GCN to promote ground-based observations. Afterglows will be monitored by Swift for days to weeks. All data will be converted into standard FITS formats and rapidly made available to the community from data centers in the US, Italy, and the UK. Swift has two additional capabilities. A hard X-ray survey will be performed with the BAT, with daily pointings covering 80% of the sky and immediate follow-up of X-ray transients. Swift will also function as a Target of Opportunity observatory for sources requiring fast response and repeated short-term (days) or longer-term (months) monitoring. Swift will be operated so that its capabilities are available to the entire community. We believe that use of Swift as a rapid-response spacecraft will open a new window of discovery on the Universe. We encourage astronomers to consider how use of this capability may lead to significant discoveries. The Swift MOC (Mission Operations Center) at Penn State will accept strong proposals for rapid observations and make the ensuing data publicly available. Swift work at Penn State is supported by NASA contract NAS5-00136.

  13. What Contributes to the Regularity of Patients with Hypertension or Diabetes Seeking Health Services? A Pilot Follow-Up, Observational Study in Two Sites in Hubei Province, China.

    Science.gov (United States)

    Feng, Da; Serrano, Ray; Ye, Ting; Tang, Shangfeng; Duan, Lei; Xu, Yuan; Yang, Jian; Liang, Yuan; Chen, Shanquan; Feng, Zhanchun; Zhang, Liang

    2016-12-21

    Regular maintenance of non-communicable chronic diseases can constrain disease progression in diabetic and hypertensive patients. To identify the individual and social factors that are associated with positive health-seeking behaviors and regular maintenance of chronic diseases, we have conducted a follow up study in 2015 on diabetic and hypertensive patients in Hubei Province. We used binary logistic regression models to determine specific factors associated with diabetic and hypertensive patients that sought healthcare services for their conditions in accordance with current Chinese Centers for Disease Prevention and Control (CDC) guidelines. Our findings show that 42.16% of 510 people living with chronic conditions (PLCDs) sought health services in line with existing guidelines. Findings also show a higher probability (8.418 times) for PLCDs seeking healthcare services at higher-tiered hospitals (secondary and tertiary hospitals) than for PLCDs seeking care at primary hospitals (odds ratio (OR) = 8.418, 95% confidence interval (CI) = 4.82, 14.27, p importance of having patient advocates who can provide support, where necessary, and encourage positive health-seeking behavior. The study also shows a negative impact on regular maintenance for PLCDs in households with high financial constraints. In contrast, the study shows positive impacts for increased household income, age, and residency in rural locations. In sum, this study underscores the importance of primary hospitals as key points of care and critical players in care coordination for PLCDs. The study provides more evidence for Chinese policymakers seeking to contain costs and improve population health. The findings also underscore the need for community-based interventions, specifically interventions that link local primary hospitals, friends/family members, and PLCDs.

  14. What Contributes to the Regularity of Patients with Hypertension or Diabetes Seeking Health Services? A Pilot Follow-Up, Observational Study in Two Sites in Hubei Province, China

    Directory of Open Access Journals (Sweden)

    Da Feng

    2016-12-01

    Full Text Available Regular maintenance of non-communicable chronic diseases can constrain disease progression in diabetic and hypertensive patients. To identify the individual and social factors that are associated with positive health-seeking behaviors and regular maintenance of chronic diseases, we have conducted a follow up study in 2015 on diabetic and hypertensive patients in Hubei Province. We used binary logistic regression models to determine specific factors associated with diabetic and hypertensive patients that sought healthcare services for their conditions in accordance with current Chinese Centers for Disease Prevention and Control (CDC guidelines. Our findings show that 42.16% of 510 people living with chronic conditions (PLCDs sought health services in line with existing guidelines. Findings also show a higher probability (8.418 times for PLCDs seeking healthcare services at higher-tiered hospitals (secondary and tertiary hospitals than for PLCDs seeking care at primary hospitals (odds ratio (OR = 8.418, 95% confidence interval (CI = 4.82, 14.27, p < 0.001. These analyses underscore the importance of having patient advocates who can provide support, where necessary, and encourage positive health-seeking behavior. The study also shows a negative impact on regular maintenance for PLCDs in households with high financial constraints. In contrast, the study shows positive impacts for increased household income, age, and residency in rural locations. In sum, this study underscores the importance of primary hospitals as key points of care and critical players in care coordination for PLCDs. The study provides more evidence for Chinese policymakers seeking to contain costs and improve population health. The findings also underscore the need for community-based interventions, specifically interventions that link local primary hospitals, friends/family members, and PLCDs.

  15. NuSTAR AND SWIFT Observations of the Fast Rotating Magnetized White Dwarf AE Aquarii

    Science.gov (United States)

    Kitaguchi, Takao; An, Hongjun; Beloborodov, Andrei M.; Gotthelf, Eric V.; Hayashi, Takayuki; Kaspi, Victoria M.; Rana, Vikram R.; Boggs, Steven E.; Christensen, Finn E.; Craig, William W.; hide

    2014-01-01

    AE Aquarii is a cataclysmic variable with the fastest known rotating magnetized white dwarf (P(sub spin) = 33.08 s). Compared to many intermediate polars, AE Aquarii shows a soft X-ray spectrum with a very low luminosity (LX (is) approximately 10(exp 31) erg per second). We have analyzed overlapping observations of this system with the NuSTAR and the Swift X-ray observatories in 2012 September. We find the 0.5-30 keV spectra to be well fitted by either an optically thin thermal plasma model with three temperatures of 0.75(+0.18 / -0.45), 2.29(+0.96 / -0.82), and 9.33 (+6.07 / -2.18) keV, or an optically thin thermal plasma model with two temperatures of 1.00 (+0.34 / -0.23) and 4.64 (+1.58 / -0.84) keV plus a power-law component with photon index of 2.50 (+0.17 / -0.23). The pulse profile in the 3-20 keV band is broad and approximately sinusoidal, with a pulsed fraction of 16.6% +/- 2.3%. We do not find any evidence for a previously reported sharp feature in the pulse profile.

  16. Using Swift observations of prompt and afterglow emission to classify GRBs.

    Science.gov (United States)

    O'Brien, Paul T; Willingale, Richard

    2007-05-15

    We present an analysis of early Burst Alert Telescope and X-ray Telescope data for 107 gamma-ray bursts (GRBs) observed by the Swift satellite. We use these data to examine the behaviour of the X-ray light curve and propose a classification scheme for GRBs based on this behaviour. As found for previous smaller samples, the earliest X-ray light curve can be well described by an exponential, which relaxes into a power-law, often with flares superimposed. The later emission is well fit using a similar functional form and we find that these two functions provide a good description of the entire X-ray light curve. For the prompt emission, the transition time between the exponential and the power-law gives a well-defined time-scale, Tp, for the burst duration. We use Tp, the spectral index of the prompt emission, betap, and the prompt power-law decay index, alphap, to define four classes of burst: short, slow, fast and soft. Bursts with slowly declining emission have spectral and temporal properties similar to the short bursts despite having longer durations. Some of these GRBs may therefore arise from similar progenitors including several types of binary system. Short bursts tend to decline more gradually than longer duration bursts and hence emit a significant fraction of their total energy at times greater than Tp. This may be due to differences in the environment or the progenitor for long, fast bursts.

  17. Swift cookbook

    CERN Document Server

    Costa, Cecil

    2015-01-01

    If you are an experienced Objective-C programmer and are looking for quick solutions to many different coding tasks in Swift, then this book is for you. You are expected to have development experience, though not necessarily with Swift.

  18. ASASSN-15LH: A SUPERLUMINOUS ULTRAVIOLET REBRIGHTENING OBSERVED BY SWIFT AND HUBBLE

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Peter J.; Yang, Yi; Wang, Lifan [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Texas A. and M. University, Department of Physics and Astronomy, 4242 TAMU, College Station, TX 77843 (United States); Cooke, Jeff; Mould, Jeremy [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn VIC 3122 (Australia); Olaes, Melanie; Quimby, Robert M. [Department of Astronomy, San Diego State University, San Diego, CA 92182 (United States); Baade, Dietrich [European Organisation for Astronomical Research in the Southern Hemisphere (ESO), Karl-Schwarzschild-Str. 2, D-85748 Garching b. München (Germany); Gehrels, Neil [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Hoeflich, Peter [Department of Physics, Florida State University, Tallahassee, FL 32306 (United States); Maund, Justyn [Department of Physics and Astronomy F39 Hicks Building, Hounsfield Road Sheffield, S3 7RH (United Kingdom); Wheeler, J. Craig [Department of Astronomy, University of Texas at Austin, Austin, TX 78712 (United States)

    2016-09-01

    We present and discuss ultraviolet and optical photometry from the Ultraviolet/Optical Telescope, X-ray limits from the X-Ray Telescope on Swift, and imaging polarimetry and ultraviolet/optical spectroscopy with the Hubble Space Telescope , all from observations of ASASSN-15lh. It has been classified as a hydrogen-poor superluminous supernova (SLSN I), making it more luminous than any other supernova observed. ASASSN-15lh is not detected in the X-rays in individual or co-added observations. From the polarimetry we determine that the explosion was only mildly asymmetric. We find the flux of ASASSN-15lh to increase strongly into the ultraviolet, with an ultraviolet luminosity 100 times greater than the hydrogen-rich, ultraviolet-bright SLSN II SN 2008es. We find that objects as bright as ASASSN-15lh are easily detectable beyond redshifts of ∼4 with the single-visit depths planned for the Large Synoptic Survey Telescope. Deep near-infrared surveys could detect such objects past a redshift of ∼20, enabling a probe of the earliest star formation. A late rebrightening—most prominent at shorter wavelengths—is seen about two months after the peak brightness, which is itself as bright as an SLSN. The ultraviolet spectra during the rebrightening are dominated by the continuum without the broad absorption or emission lines seen in SLSNe or tidal disruption events (TDEs) and the early optical spectra of ASASSN-15lh. Our spectra show no strong hydrogen emission, showing only Ly α absorption near the redshift previously found by optical absorption lines of the presumed host. The properties of ASASSN-15lh are extreme when compared to either SLSNe or TDEs.

  19. Swift , XMM - Newton , and NuSTAR Observations of PSR J2032+4127/MT91 213

    Energy Technology Data Exchange (ETDEWEB)

    Li, K. L. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Kong, A. K. H. [Astrophysics, Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom); Tam, P. H. T. [School of Physics and Astronomy, Sun Yat-sen University, Zhuhai 519082 (China); Hou, X. [Yunnan Observatories, Chinese Academy of Sciences, 396 Yangfangwang, Guandu District, Kunming 650216 (China); Takata, J. [Institute of Particle Physics and Astronomy, Huazhong University of Science and Technology (China); Hui, C. Y., E-mail: liliray@pa.msu.edu [Department of Astronomy and Space Science, Chungnam National University, Daejeon (Korea, Republic of)

    2017-07-10

    We report our recent Swift , NuSTAR , and XMM - Newton X-ray and Lijiang optical observations on PSR J2032+4127/MT91 213, the γ -ray binary candidate with a period of 45–50 years. The coming periastron of the system was predicted to be in 2017 November, around which high-energy flares from keV to TeV are expected. Recent studies with Chandra and Swift X-ray observations taken in 2015/2016 showed that its X-ray emission has been brighter by a factors of ∼10 than that before 2013, probably revealing some ongoing activities between the pulsar wind and the stellar wind. Our new Swift /XRT lightcurve shows no strong evidence of a single vigorous brightening trend, but rather several strong X-ray flares on weekly to monthly timescales with a slowly brightening baseline, namely the low state. The NuSTAR and XMM - Newton observations taken during the flaring and the low states, respectively, show a denser environment and a softer power-law index during the flaring state, implying that the pulsar wind interacted with the stronger stellar winds of the companion to produce the flares. These precursors would be crucial in studying the predicted giant outburst from this extreme γ -ray binary during the periastron passage in late 2017.

  20. SWIFT ULTRAVIOLET OBSERVATIONS OF SUPERNOVA 2014J IN M82: LARGE EXTINCTION FROM INTERSTELLAR DUST

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Peter J.; Smitka, Michael T.; Wang, Lifan; Krisciunas, Kevin [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Texas A. and M. University, Department of Physics and Astronomy, 4242 TAMU, College Station, TX 77843 (United States); Breeveld, Alice; Kuin, N. Paul; Page, Mat [Mullard Space Science Laboratory, University College London, Holmbury St. Mary, Dorking Surrey, RH5 6NT (United Kingdom); De Pasquale, Massimiliano [Instituto di Astrofisica Spaziale e Fisica Cosmica di Palermo Via Ugo la Malfa 153 90146 Palermo (Italy); Hartmann, Dieter H. [Clemson University, Department of Physics and Astronomy, Kinard Lab of Physics, Clemson, SC 29634-0978 (United States); Milne, Peter A. [Steward Observatory, University of Arizona, Tucson, AZ 85719 (United States); Siegel, Michael [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States)

    2015-05-20

    We present optical and ultraviolet (UV) photometry and spectra of the very nearby and highly reddened supernova (SN) 2014J in M82 obtained with the Swift Ultra-Violet/Optical Telescope (UVOT). Comparison of the UVOT grism spectra of SN 2014J with Hubble Space Telescope observations of SN2011fe or UVOT grism spectra of SN 2012fr are consistent with an extinction law with a low value of R{sub V} ∼1.4. The high reddening causes the detected photon distribution in the broadband UV filters to have a much longer effective wavelength than for an unreddened SN. The light curve evolution is consistent with this shift and does not show a flattening due to photons being scattered back into the line of sight (LOS). The light curve shapes and color evolution are inconsistent with a contribution scattered into the LOS by circumstellar dust. We conclude that most or all of the high reddening must come from interstellar dust. We show that even for a single dust composition, there is not a unique reddening law caused by circumstellar scattering. Rather, when considering scattering from a time-variable source, we confirm earlier studies that the reddening law is a function of the dust geometry, column density, and epoch. We also show how an assumed geometry of dust as a foreground sheet in mixed stellar/dust systems will lead to a higher inferred R{sub V}. Rather than assuming the dust around SNe is peculiar, SNe may be useful probes of the interstellar reddening laws in other galaxies.

  1. Close-up of primary and secondary asteroseismic CoRoT targets and the ground-based follow-up observations

    Energy Technology Data Exchange (ETDEWEB)

    Uytterhoeven, K; Poretti, E; Rainer, M; Mantegazza, L [INAF-Brera Astronomical Observatory, Via E. Bianchi 46, 23807 Merate (Italy); Zima, W; Aerts, C; Morel, T; Lefever, K [Institute of Astronomy, KULeuven, Celestijnenlaan 200D, 3001 Leuven (Belgium); Miglio, A [Institut d' Astrophysique et de Geophysique de l' Universite de Liege, Allee du 6 Aout 17, 4000 Liege (Belgium); Amado, P J; MartIn-Ruiz, S [Instituto de AstrofIsica de AndalucIa (CSIC), Apartado 3004, 18080 Granada (Spain); Mathias, P; Valtier, J C [Observatoire de la Cote d' Azur, GEMINI, CNRS, Universite Nice Sophia-Antipolis, BP 4229, 06304 Nice Cedex 4 (France); Paparo, M; Benkoe, J M [Konkoly Observatory, PO Box 67, 1525 Budapest (Hungary)], E-mail: katrien.uytterhoeven@brera.inaf.it

    2008-10-15

    To optimise the science results of the asteroseismic part of the CoRoT satellite mission a complementary simultaneous ground-based observational campaign is organised for selected CoRoT targets. The observations include both high-resolution spectroscopic and multicolour photometric data. We present the preliminary results of the analysis of the ground-based observations of three targets. A line-profile analysis of 216 high-resolution FEROS spectra of the {delta} Sct star HD 50844 reveals more than ten pulsation frequencies in the frequency range 5-18 d{sup -1}, including possibly one radial fundamental mode (6.92 d{sup -1}). Based on more than 600 multi-colour photometric datapoints of the {beta} Cep star HD 180642, spanning about three years and obtained with different telescopes and different instruments, we confirm the presence of a dominant radial mode {nu}{sub 1} = 5.48695 d{sup -1}, and detect also its first two harmonics. We find evidence for a second mode {nu}{sub 2} = 0.3017 d{sup -1}, possibly a g-mode, and indications for two more frequencies in the 7-8 d{sup -1} domain. From Stromgren photometry we find evidence for the hybrid 5 Sct/{gamma} Dor character of the F0 star HD 44195, as frequencies near 3 d{sup -1} and 21 d{sup -1} are detected simultaneously in the different filters.

  2. [Spontaneous changes in carbohydrate tolerance and insulin secretion in persons with indications of disturbed carbohydrate tolerance. Preliminary results and follow-up observations for 7 years].

    Science.gov (United States)

    Ratzmann, K P; Schulz, B; Witt, S; Heinke, P; Michaelis, D

    1980-03-15

    115 patients with normal weight and 15 adipose persons with suspicion of a disturbance of the carbohydrate metabolism were characterized by means of a glucose infusion test lasting two hours concerning the carbohydrate tolerance and insulin secretion. Longitudinal analyses of the spontaneous behaviour of the carbohydrate tolerance and insulin secretion depending on the degree of the carbohydrate tolerance up to duration of the observation of 7 years. A deterioration of the carbohydrate tolerance was to be proved in 21% of 87 persons with normal carbohydrate tolerance within two years. With normal carbohydrate tolerance within two years. With an increase of the duration of the observation up to 7 years the frequency of disturbances of the carbohydrate tolerance increases to 30%. This development cannot be coordinated to a certain type of insulin secretion. In the individual case a deterioration of the carbohydrate tolerance may be associated with an increase or reduction of the glucose stimulated insuline secretion. An improvement of the carbohydrate tolerance was observed in 15 (54%) of 28 patients with disturbed carbohydrate tolerance within 2 years. In a group with pathological carbohydrate tolerance this development was associated with a significant reduction of the basic and glucose stimulated insulin secretion. In all patients with improved carbohydrate tolerance on the side of the insulin secretion primarily the type of "normal response" was present. The lacking relation between changes of the B-cell function and the carbohydrate tolerance emphasizes the importance of other factors, such as a peripheral insulin resistance, for the development of disturbances in the carbohydrate metabolism.

  3. Live Donors of the Initial Observational Study of Uterus Transplantation-Psychological and Medical Follow-Up Until 1 Year After Surgery in the 9 Cases.

    Science.gov (United States)

    Kvarnström, Niclas; Järvholm, Stina; Johannesson, Liza; Dahm-Kähler, Pernilla; Olausson, Michael; Brännström, Mats

    2017-03-01

    The first prospective observational study of uterus transplantation was initiated in 2013 with live donation to 9 women with absolute uterine factor infertility. We explored the medical complications and psychosocial wellbeing of the donors during the first postoperative year. Complications were registered and graded according to the Clavien-Dindo (C-D) classification. Symptoms related to the surgery were registered. Data on length of hospital stay, sick leave, socioeconomic parameters, and life events were obtained. Psychological evaluations (Psychological General Well-Being, Dyadic Adjustment Scale, Hospital Anxiety and Depression Scale [HADS], SF-36) questionnaires focusing on quality of life, mood, and relationship, were conducted at inclusion and at 3, 6, and 12 months after uterus donation. One major surgical complication (C-D IIIb) occurred. A ureteric-vaginal fistula developed 2 weeks after uterus procurement. The fistula was surgically repaired. Two self-reported and transient complications (C-D I) were noted (nocturia, meralgia paresthetica). Hospital stays of all donors were 6 days and median sick leave was 56 days (range, 14-132). At inclusion, median scores exceeded the normative values of the Swedish population in Psychological General Well-Being and Dyadic Adjustment Scale. HADS-Anxiety was detected preoperatively in 1 donor. Two donors exceeded 10-point declines in SF-36 summary scores and increased their HADS scores by 6 points during the observation period. All donors returned to their predonation levels of physical health. The results support that it is feasible to retrieve a uterus safely from a live donor. Further studies are needed to better evaluate the method.

  4. Respiratory physiotherapy and incidence of pulmonary complications in off-pump coronary artery bypass graft surgery: an observational follow-up study

    Directory of Open Access Journals (Sweden)

    Pértega-Díaz Sonia

    2009-07-01

    Full Text Available Abstract Background Heart surgery is associated with an occurrence of pulmonary complications. The aim of this study was to determine whether pre-surgery respiratory physiotherapy reduces the incidence of post-surgery pulmonary complications. Methods Observational study of 263 patients submitted to off-pump coronary artery bypass grafting (CABG surgery at the A Coruña University Hospital (Spain. 159 (60.5% patients received preoperative physiotherapy. The fact that patients received preoperative physiotherapy or not was related to whether they were admitted to the cardiac surgery unit or to an alternative unit due to a lack of beds. A physiotherapist provided a daily session involving incentive spirometry, deep breathing exercises, coughing and early ambulation. A logistic regression analysis was carried out in order to identify variables associated with pulmonary complications. Results Both groups of patients (those that received physiotherapy and those that did not were similar in age, sex, body mass index, creatinine, ejection fraction, number of affected vessels, O2 basal saturation, prevalence of diabetes, dyslipidemia, exposure to tobacco, age at smoking initiation, number of cigarettes/day and number of years as a smoker. The most frequent postoperative complications were hypoventilation (90.7%, pleural effusion (47.5% and atelectasis (24.7%. In the univariate analysis, prophylactic physiotherapy was associated with a lower incidence of atelectasis (17% compared to 36%, p = 0.01. After taking into account age, sex, ejection fraction and whether the patients received physiotherapy or not, we observed that receiving physiotherapy is the variable with an independent effect on predicting atelectasis. Conclusion Preoperative respiratory physiotherapy is related to a lower incidence of atelectasis.

  5. Respiratory physiotherapy and incidence of pulmonary complications in off-pump coronary artery bypass graft surgery: an observational follow-up study.

    Science.gov (United States)

    Yánez-Brage, Isabel; Pita-Fernández, Salvador; Juffé-Stein, Alberto; Martínez-González, Ursicino; Pértega-Díaz, Sonia; Mauleón-García, Angeles

    2009-07-28

    Heart surgery is associated with an occurrence of pulmonary complications. The aim of this study was to determine whether pre-surgery respiratory physiotherapy reduces the incidence of post-surgery pulmonary complications. Observational study of 263 patients submitted to off-pump coronary artery bypass grafting (CABG) surgery at the A Coruña University Hospital (Spain). 159 (60.5%) patients received preoperative physiotherapy. The fact that patients received preoperative physiotherapy or not was related to whether they were admitted to the cardiac surgery unit or to an alternative unit due to a lack of beds. A physiotherapist provided a daily session involving incentive spirometry, deep breathing exercises, coughing and early ambulation. A logistic regression analysis was carried out in order to identify variables associated with pulmonary complications. Both groups of patients (those that received physiotherapy and those that did not) were similar in age, sex, body mass index, creatinine, ejection fraction, number of affected vessels, O2 basal saturation, prevalence of diabetes, dyslipidemia, exposure to tobacco, age at smoking initiation, number of cigarettes/day and number of years as a smoker. The most frequent postoperative complications were hypoventilation (90.7%), pleural effusion (47.5%) and atelectasis (24.7%). In the univariate analysis, prophylactic physiotherapy was associated with a lower incidence of atelectasis (17% compared to 36%, p = 0.01). After taking into account age, sex, ejection fraction and whether the patients received physiotherapy or not, we observed that receiving physiotherapy is the variable with an independent effect on predicting atelectasis. Preoperative respiratory physiotherapy is related to a lower incidence of atelectasis.

  6. The Nature of the X-Ray Binary IGR J19294+1816 from INTEGRAL, RXTE, and Swift Observations

    Science.gov (United States)

    Rodriquez, J.; Tomsick, J. A.; Bodaghee, A.; ZuritaHeras, J.-A.; Chaty, S.; Paizis, A.; Corbel, S.

    2009-01-01

    We report the results of a high-energy multi-instrumental campaign with INTEGRAL, RXTE, and Swift of the recently discovered INTEGRAL source IGR J19294+ 1816. The Swift/XRT data allow us to refine the position of the source to R.A. (J2000) = 19h 29m 55.9s, Decl. (J2000) = +18 deg 18 feet 38 inches . 4 (+/- 3 inches .5), which in turn permits us to identify a candidate infrared counterpart. The Swift and RXTE spectra are well fitted with absorbed power laws with hard (Gamma approx 1) photon indices. During the longest Swift observation, we obtained evidence of absorption in true excess to the Galactic value, which may indicate some intrinsic absorption in this source. We detected a strong (P = 40%) pulsations at 12.43781 (+/- 0.00003) s that we interpret as the spin period of a pulsar. All these results, coupled with the possible 117 day orbital period, point to IGR J19294+ 1816 being an high-mass X-ray binary (HMXB) with a Be companion star. However, while the long-term INTEGRAL/IBIS/ISGRI 18-40 keV light curve shows that the source spends most of its time in an undetectable state, we detect occurrences of short (2000-3000 s) and intense flares that are more typical of supergiant fast X-ray transients. We therefore cannot make firm conclusions on the type of system, and we discuss the possible implication of IGR J19294+1816 being an Supergiant Fast X-ray Transient (SFXT).

  7. MALT-45: A 7 mm survey of the southern Galaxy - II. ATCA follow-up observations of 44 GHz class I methanol masers

    Science.gov (United States)

    Jordan, Christopher H.; Walsh, Andrew J.; Breen, Shari L.; Ellingsen, Simon P.; Voronkov, Maxim A.; Hyland, Lucas J.

    2017-11-01

    We detail interferometric observations of 44 GHz class I methanol masers detected by MALT-45 (a 7 mm unbiased auto-correlated spectral-line Galactic-plane survey) using the Australia Telescope Compact Array. We detect 238 maser spots across 77 maser sites. Using high-resolution positions, we compare the class I CH3OH masers to other star formation maser species, including CS (1-0), SiO v = 0 and the H53 α radio-recombination line. Comparison between the cross- and auto-correlated data has allowed us to also identify quasi-thermal emission in the 44 GHz class I methanol maser line. We find that the majority of class I methanol masers have small spatial and velocity ranges (<0.5 pc and <5 km s-1), and closely trace the systemic velocities of associated clouds. Using 870 μm dust continuum emission from the ATLASGAL survey, we determine clump masses associated with class I masers, and find that they are generally associated with clumps between 1000 and 3000 M⊙. For each class I methanol maser site, we use the presence of OH masers and radio recombination lines to identify relatively evolved regions of high-mass star formation; we find that maser sites without these associations have lower luminosities and preferentially appear towards dark infrared regions.

  8. Marrow signal changes observed in follow-up whole-body MRI studies in children and young adults with neurofibromatosis type 1 treated with imatinib mesylate (Gleevec) for plexiform neurofibromas

    Energy Technology Data Exchange (ETDEWEB)

    Karmazyn, Boaz; Cohen, Mervyn D. [Riley Hospital for Children, Indiana University Health, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN (United States); Jennings, Samuel Gregory [Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indianapolis, IN (United States); Robertson, Kent A. [Riley Hospital for Children, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN (United States)

    2012-10-15

    We observed bone marrow signal changes (BMSC) in patients with plexiform neurofibromas after treatment with imatinib mesylate (Gleevec). To evaluate the pattern and natural history of BMSC. The data were obtained from a pilot study of imatinib mesylate in patients with plexiform neurofibromas. All patients underwent baseline and sequential whole-body STIR 1.5-T MRI after treatment. The bone marrow signal on MRI was evaluated for abnormalities, location and pattern, and any change on follow-up studies. The study group included 16 patients (8 males) with a median age of 14 years (range 4 to 25 years). The mean whole-body MRI follow-up duration was 1.9 years. Of the 16 patients, 14 (88%) developed BMSC. The signal change was asymmetrical in 9 of the 14 patients (64%). The appendicular skeleton was involved in all 14 patients and the axial skeleton in 3 patients (21%). BMSC was followed in 13 patients and decreased signal was seen in 9 patients (69%) after a mean duration of 1.3 years of treatment (range 0.6 to 2.9 years); no complications were observed. BMSC appeared in most patients with neurofibromatosis type 1 following treatment with imatinib mesylate. BMSC was unusually asymmetrical and involved the lower extremities. On follow-up, BMSC often showed a decrease without complications. (orig.)

  9. Appraisal of elastic follow up

    International Nuclear Information System (INIS)

    Roche, R.L.

    1981-01-01

    Elastic computations are widely used in structural analysis, and their results are used when material behaviour is non elastic. The current practice is the partition of the computed stress between primary and secondary stress. The basic characteristic of primary stress is that it is not self limiting. On the contrary the basic characteristic of a secondary stress is that it is self limiting, and failure from one application of the stress is not to be expected. It must be emphasized that self limitation is not sufficient and that it is also necessary that strains are small enough to avoid any material disorder. Unfortunately, elastic computations do not give real strain distribution and computed strain in highly stressed areas can be magnified under conditions of plastic temperature is high enough, an undesirable amount of creep occurs in areas of reduced strength and failure can happen. In creep range, to avoid elastic follow up, the most important part of elastically computed stress is considered as primary. This practice is over conservative, and the aim of this paper is to provide indications to choise what fraction of a self limiting stress can be considered as secondary. (orig./GL)

  10. Changes in pain and concurrent pain medication use following compounded topical analgesic treatment for chronic pain: 3- and 6-month follow-up results from the prospective, observational Optimizing Patient Experience and Response to Topical Analgesics study.

    Science.gov (United States)

    Gudin, Jeffrey A; Brennan, Michael J; Harris, E Dennis; Hurwitz, Peter L; Dietze, Derek T; Strader, James D

    2017-01-01

    Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. This prospective, observational study evaluated changes from baseline in overall mean severity and interference scores on the Brief Pain Inventory scale and the use of concurrent pain medications at 3- and 6-month follow-up assessments in chronic pain patients treated with topical analgesics. Changes in pain severity and interference and medication usage were compared between treated patients and unmatched and matched controls. The unmatched intervention group (unmatched-IG) included 631 patients who completed baseline and 3-month follow-up surveys (3-month unmatched-IG) and 158 who completed baseline and 6-month follow-up assessments (6-month unmatched-IG). Baseline and 3-month follow-up data were provided by 76 unmatched controls and 76 matched controls (3-month unmatched-CG and matched-CG), and 51 unmatched and 36 matched patients completed baseline and 6-month follow-up surveys (6-month unmatched-CG and matched-CG). Baseline demographic characteristics and mean pain severity and interference scores were similar between groups. There were statistically significant decreases from baseline in mean pain severity and interference scores within the 3- and 6-month unmatched-IG (all P <0.001). Significantly greater decreases in the mean change from baseline in pain severity and interference scores were evident for the 3- and 6-month unmatched-IG versus unmatched-CG (all P <0.001), with similar results when the 3- and 6-month matched-IG and matched-CG were compared. A higher percentage of the 3- and 6-month unmatched-IG and matched-IG de-escalated use of concurrent pain medications (all P <0.001), while significantly higher percentages of the unmatched-CG and matched-CG escalated medication use. Side effects were reported by <1% of the

  11. Changes in pain and concurrent pain medication use following compounded topical analgesic treatment for chronic pain: 3- and 6-month follow-up results from the prospective, observational Optimizing Patient Experience and Response to Topical Analgesics study

    Directory of Open Access Journals (Sweden)

    Gudin JA

    2017-10-01

    Full Text Available Jeffrey A Gudin,1 Michael J Brennan,2 E Dennis Harris,3 Peter L Hurwitz,3 Derek T Dietze,4 James D Strader5 1Pain Medicine and Palliative Care, Englewood Hospital and Medical Center, Englewood, NJ, 2The Pain Center of Fairfield, Fairfield, CT, 3Clarity Science, Austin, TX, 4Metrics for Learning, LLC, Queen Creek, AZ, 5Safe Harbor Compliance and Clinical Services, LLC, Austin, TX, USA Background: Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics.Methods: This prospective, observational study evaluated changes from baseline in overall mean severity and interference scores on the Brief Pain Inventory scale and the use of concurrent pain medications at 3- and 6-month follow-up assessments in chronic pain patients treated with topical analgesics. Changes in pain severity and interference and medication usage were compared between treated patients and unmatched and matched controls.Results: The unmatched intervention group (unmatched-IG included 631 patients who completed baseline and 3-month follow-up surveys (3-month unmatched-IG and 158 who completed baseline and 6-month follow-up assessments (6-month unmatched-IG. Baseline and 3-month follow-up data were provided by 76 unmatched controls and 76 matched controls (3-month unmatched-CG and matched-CG, and 51 unmatched and 36 matched patients completed baseline and 6-month follow-up surveys (6-month unmatched-CG and matched-CG. Baseline demographic characteristics and mean pain severity and interference scores were similar between groups. There were statistically significant decreases from baseline in mean pain severity and interference scores within the 3- and 6-month unmatched-IG (all P<0.001. Significantly greater decreases in the mean change from baseline in pain severity and interference scores were evident for the

  12. The REDUCE Follow-Up Study: low rate of new prostate cancer diagnoses observed during a 2-year, observational, followup study of men who participated in the REDUCE trial.

    Science.gov (United States)

    Grubb, Robert L; Andriole, Gerald L; Somerville, Matthew C; Mahoney, Chrysa; Manyak, Michael J; Castro, Ramiro

    2013-03-01

    The primary objective of the REDUCE (REduction by DUtasteride of prostate Cancer Events) Follow-Up Study was to collect data on the occurrence of newly diagnosed prostate cancers for 2 years beyond the 4-year REDUCE study. The 4-year REDUCE study evaluated prostate cancer risk reduction in men taking dutasteride. This 2-year observational study followed men from REDUCE with a clinic visit shortly after study conclusion and with up to 2 annual telephone calls during which patient reported data were collected regarding prostate cancer events, chronic medication use, prostate specific antigen levels and serious adverse events. No study drug was provided and all biopsies during the 2-year followup were performed for cause. The primary objective was to collect data on the occurrence of new biopsy detectable prostate cancers. Secondary end points included assessment of Gleason score and serious adverse events. A total of 2,751 men enrolled in the followup study with numbers similar to those of the REDUCE former treatment groups (placebo and dutasteride). Few new prostate cancers were detected during the 2-year followup period in either former treatment group. A greater number of cancers were detected in the former dutasteride group than in the former placebo group (14 vs 7 cases). No Gleason score 8-10 prostate cancers were detected in either former treatment group based on central pathology review. No new safety issues were identified during the study. Two years of followup of the REDUCE study cohort demonstrated a low rate of new prostate cancer diagnoses in the former placebo and dutasteride treated groups. No new Gleason 8-10 cancers were detected. Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  13. Three years of Swift/BAT Survey of AGN: Reconciling Theory and Observations?

    Energy Technology Data Exchange (ETDEWEB)

    Burlon, D.; /Garching, Max Planck Inst., MPE; Ajello, M.; /SLAC /KIPAC, Menlo Park; Greiner, J.; /Garching, Max Planck Inst., MPE; Comastri, A.; /Muenchen, Tech. U. Universe; Merloni, A.; /Garching, Max Planck Inst., MPE /Muenchen, Tech. U. Universe; Gehrels, N.; /NASA, Goddard

    2011-02-07

    It is well accepted that unabsorbed as well as absorbed AGN are needed to explain the nature and the shape of the Cosmic X-ray background, even if the fraction of highly absorbed objects (dubbed Compton-thick sources) substantially still escapes detection. We derive and analyze the absorption distribution using a complete sample of AGN detected by Swift-BAT in the first three years of the survey. The fraction of Compton-thick AGN represents only 4.6% of the total AGN population detected by Swift-BAT. However, we show that once corrected for the bias against the detection of very absorbed sources the real intrinsic fraction of Compton-thick AGN is 20{sub -6}{sup +9}%. We proved for the first time (also in the BAT band) that the anti-correlation of the fraction of absorbed AGN and luminosity it tightly connected to the different behavior of the luminosity functions (XLFs) of absorbed and unabsorbed AGN. This points towards a difference between the two subsamples of objects with absorbed AGN being, on average, intrinsically less luminous than unobscured ones. Moreover the XLFs show that the fraction of obscured AGN might also decrease at very low luminosity. This can be successfully interpreted in the framework of a disk cloud outflow scenario as the disappearance of the obscuring region below a critical luminosity. Our results are discussed in the framework of population synthesis models and the origin of the Cosmic X-ray Background.

  14. THREE-YEAR SWIFT-BAT SURVEY OF ACTIVE GALACTIC NUCLEI: RECONCILING THEORY AND OBSERVATIONS?

    International Nuclear Information System (INIS)

    Burlon, D.; Greiner, J.; Merloni, A.; Ajello, M.; Comastri, A.; Gehrels, N.

    2011-01-01

    It is well accepted that unabsorbed as well as absorbed active galactic nuclei (AGNs) are needed to explain the nature and shape of the Cosmic X-ray background (CXB), even if the fraction of highly absorbed objects (dubbed Compton-thick sources) still substantially escapes detection. We derive and analyze the absorption distribution using a complete sample of AGNs detected by Swift-BAT in the first three years of the survey. The fraction of Compton-thick AGNs represents only 4.6% of the total AGN population detected by Swift-BAT. However, we show that once corrected for the bias against the detection of very absorbed sources the real intrinsic fraction of Compton-thick AGNs is 20 -6 +9 %. We proved for the first time (also in the Burst Alert Telescope (BAT) band) that the anti-correlation of the fraction of absorbed AGNs and luminosity is tightly connected to the different behavior of the X-ray luminosity functions (XLFs) of absorbed and unabsorbed AGNs. This points toward a difference between the two subsamples of objects with absorbed AGNs being, on average, intrinsically less luminous than unobscured ones. Moreover, the XLFs show that the fraction of obscured AGNs might also decrease at very low luminosity. This can be successfully interpreted in the framework of a disk cloud outflow scenario as the disappearance of the obscuring region below a critical luminosity. Our results are discussed in the framework of population synthesis models and the origin of the CXB.

  15. Follow-up of high energy neutrinos detected by the ANTARES telescope

    Directory of Open Access Journals (Sweden)

    Mathieu Aurore

    2016-01-01

    Full Text Available The ANTARES telescope is well-suited to detect high energy neutrinos produced in astrophysical transient sources as it can observe a full hemisphere of the sky with a high duty cycle. Potential neutrino sources are gamma-ray bursts, core-collapse supernovae and flaring active galactic nuclei. To enhance the sensitivity of ANTARES to such sources, a detection method based on follow-up observations from the neutrino direction has been developed. This program, denoted as TAToO, includes a network of robotic optical telescopes (TAROT, Zadko and MASTER and the Swift-XRT telescope, which are triggered when an “interesting” neutrino is detected by ANTARES. A follow-up of special events, such as neutrino doublets in time/space coincidence or a single neutrino having a very high energy or in the specific direction of a local galaxy, significantly improves the perspective for the detection of transient sources. The analysis of early and long term follow-up observations to search for fast and slowly varying transient sources, respectively, has been performed and the results covering optical and X-ray data are presented in this contribution.

  16. The LCOGT NEO Follow-up Network

    Science.gov (United States)

    Lister, Tim A.; Greenstreet, S.; Gomez, E.; Christensen, E.; Larson, S.

    2016-01-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) has deployed a homogeneous telescope network of nine 1-meter telescopes to four locations in the northern and southern hemispheres, with a planned network size of twelve 1-meter telescopes at 6 locations. This network is very versatile and is designed to respond rapidly to target of opportunity events and also to perform long term monitoring of slowly changing astronomical phenomena. The global coverage of the network and the apertures of telescope available make LCOGT ideal for follow-up and characterization of Solar System objects (e.g. asteroids, Kuiper Belt Objects, comets, Near-Earth Objects (NEOs)) and additionally for the discovery of new objects. We are using the LCOGT network to confirm newly detected NEO candidates produced by the major sky surveys such as Catalina Sky Survey (CSS) and PanSTARRS (PS1&2) and several hundred targets are now being followed per year. An increasing amount of time is being spent to obtain follow-up astrometry and photometry for radar-targeted objects and those on the Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) or Asteroid Retrieval Mission (ARM) lists in order to improve the orbits, determine the light curves and rotation periods and improve the characterization. This will be extended to obtain more light curves of other NEOs which could be targets. Recent results have included the first period determinations for several of the Goldstone-targeted NEOs. We are in the process of building a NEO follow-up portal which will allow professionals, amateurs and Citizen Scientists to plan, schedule and analyze NEO imaging and spectroscopy observations and data using the LCOGT Network and to act as a co-ordination hub for the NEO follow-up efforts.

  17. Observations of V0332+53 during the 2015 outburst using Fermi/GBM, MAXI, Swift and INTEGRAL

    Science.gov (United States)

    Baum, Zachary A.; Cherry, Michael L.; Rodi, James

    2017-06-01

    We present the light curves, spectra and hardness-intensity diagram (HID) of the high-mass X-ray binary V0332+53 using Fermi/GBM, MAXI, Swift/BAT and INTEGRAL through its 2015 Type II outburst. We observe characteristic features in the X-ray emission (2-50 keV) due to periastron passages, the dynamical time-scale of the accretion disc, and changes within the accretion column between a radiation-dominated flow and a flow dominated by Coulomb interactions. Based on the HID and the light curves, the critical luminosity is observed to decrease by ˜5 per cent to 7 per cent during the outburst, signalling a decrease in the magnetic field.

  18. The soft spectral state of the black hole candidate IGR J17091-3624 observed by INTEGRAL and Swift

    DEFF Research Database (Denmark)

    Del Santo, M.; Kuulkers, E.; Bozzo, E.

    2011-01-01

    The currently on-going outburst of the black hole candidate (BHC) IGR J17091-3624 (ATel #3144, #3159, #3167) has been recently observed simultaneously with INTEGRAL and Swift. The source was in the IBIS FOV on 2011 Feb. 28 from 17:45 to 21:23 (UTC; exposure time 7.7 ks) during the Galactic Bulge......, a better description of the spectrum (confirmed by the F-test) can be obtained adding a disk black-body component (red. chi^2=1.1 (302 d.o.f.)). The fit of the joint XRT+IBIS/ISGRI broad-band spectrum (0.8-200 keV) gives an absorption column density of N_H=1.00+/-0.06, a disc black-body temperature of 1...

  19. Swift Panchromatic Observations of the Bright Gamma-Ray Burst GRB 050525a

    Science.gov (United States)

    Blustin, A. J.; Band, D.; Barthelmy, S.; Boyd, P.; Capalbi, M.; Holland, S. T.; Marshall, F. E.; Mason, K. O.; Perri, M.; Poole, T.; Roming, P.; Rosen, S.; Schady, P.; Still, M.; Zhang, B.; Angelini, L.; Barbier, L.; Beardmore, A.; Breeveld, A.; Burrows, D. N.; Cummings, J. R.; Cannizzo, J.; Campana, S.; Chester, M. M.; Chincarini, G.; Cominsky, L. R.; Cucchiara, A.; de Pasquale, M.; Fenimore, E. E.; Gehrels, N.; Giommi, P.; Goad, M.; Gronwall, C.; Grupe, D.; Hill, J. E.; Hinshaw, D.; Hunsberger, S.; Hurley, K. C.; Ivanushkina, M.; Kennea, J. A.; Krimm, H. A.; Kumar, P.; Landsman, W.; La Parola, V.; Markwardt, C. B.; McGowan, K.; Mészáros, P.; Mineo, T.; Moretti, A.; Morgan, A.; Nousek, J.; O'Brien, P. T.; Osborne, J. P.; Page, K.; Page, M. J.; Palmer, D. M.; Parsons, A. M.; Rhoads, J.; Romano, P.; Sakamoto, T.; Sato, G.; Tagliaferri, G.; Tueller, J.; Wells, A. A.; White, N. E.

    2006-02-01

    The bright gamma-ray burst GRB 050525a has been detected with the Swift observatory, providing unique multiwavelength coverage from the very earliest phases of the burst. The X-ray and optical/UV afterglow decay light curves both exhibit a steeper slope ~0.15 days after the burst, indicative of a jet break. This jet break time combined with the total gamma-ray energy of the burst constrains the opening angle of the jet to be 3.2d. We derive an empirical ``time-lag'' redshift from the BAT data of ẑ=0.69+/-0.02, in good agreement with the spectroscopic redshift of 0.61. Prior to the jet break, the X-ray data can be modeled by a simple power law with index α=-1.2. However, after 300 s the X-ray flux brightens by about 30% compared to the power-law fit. The optical/UV data have a more complex decay, with evidence of a rapidly falling reverse shock component that dominates in the first minute or so, giving way to a flatter forward shock component at later times. The multiwavelength X-ray/UV/optical spectrum of the afterglow shows evidence for migration of the electron cooling frequency through the optical range within 25,000 s. The measured temporal decay and spectral indexes in the X-ray and optical/UV regimes compare favorably with the standard fireball model for gamma-ray bursts assuming expansion into a constant-density interstellar medium.

  20. Spectroscopic follow up of Kepler planet candidates

    DEFF Research Database (Denmark)

    Latham..[], D. W.; Cochran, W. D.; Marcy, G.W.

    2010-01-01

    and not planets, our strategy is to start with reconnaissance spectroscopy using smaller telescopes, to sort out and reject as many of the false positives as possible before going to Keck. During the first Kepler observing season in 2009, more than 100 nights of telescope time were allocated for this work, using......Spectroscopic follow-up observations play a crucial role in the confirmation and characterization of transiting planet candidates identified by Kepler. The most challenging part of this work is the determination of radial velocities with a precision approaching 1 m/s in order to derive masses from...... spectroscopic orbits. The most precious resource for this work is HIRES on Keck I, to be joined by HARPS-North on the William Herschel Telescope when that new spectrometer comes on line in two years. Because a large fraction of the planet candidates are in fact stellar systems involving eclipsing stars...

  1. Spectroscopic follow up of Kepler planet candidates

    DEFF Research Database (Denmark)

    Latham..[], D. W.; Cochran, W. D.; Marcy, G.W.

    2010-01-01

    Spectroscopic follow-up observations play a crucial role in the confirmation and characterization of transiting planet candidates identified by Kepler. The most challenging part of this work is the determination of radial velocities with a precision approaching 1 m/s in order to derive masses from...... spectroscopic orbits. The most precious resource for this work is HIRES on Keck I, to be joined by HARPS-North on the William Herschel Telescope when that new spectrometer comes on line in two years. Because a large fraction of the planet candidates are in fact stellar systems involving eclipsing stars...... and not planets, our strategy is to start with reconnaissance spectroscopy using smaller telescopes, to sort out and reject as many of the false positives as possible before going to Keck. During the first Kepler observing season in 2009, more than 100 nights of telescope time were allocated for this work, using...

  2. The First Simultaneous Microlensing Observations by Two Space Telescopes: Spitzer and Swift Reveal a Brown Dwarf in Event OGLE-2015-BLG-1319

    Science.gov (United States)

    Shvartzvald, Y.; Li, Z.; Udalski, A.; Gould, A.; Sumi, T.; Street, R. A.; Calchi Novati, S.; Hundertmark, M.; Bozza, V.; Beichman, C.; hide

    2016-01-01

    Simultaneous observations of microlensing events from multiple locations allow for the breaking of degeneracies between the physical properties of the lensing system, specifically by exploring different regions of the lens plane and by directly measuring the "microlens parallax". We report the discovery of a 30-65M J brown dwarf orbiting a K dwarf in the microlensing event OGLE-2015-BLG-1319. The system is located at a distance of approximately 5 kpc toward the Galactic Bulge. The event was observed by several ground-based groups as well as by Spitzer and Swift, allowing a measurement of the physical properties. However, the event is still subject to an eight-fold degeneracy, in particular the well-known close-wide degeneracy, and thus the projected separation between the two lens components is either approximately 0.25 au or approximately 45 au. This is the first microlensing event observed by Swift, with the UVOT camera. We study the region of microlensing parameter space to which Swift is sensitive, finding that though Swift could not measure the microlens parallax with respect to ground-based observations for this event, it can be important for other events. Specifically, it is important for detecting nearby brown dwarfs and free-floating planets in high magnification events.

  3. Fermi/LAT and Swift/XRT observations of XSS J12270-4859/2FGL J1227.7-4853

    Science.gov (United States)

    Tam, P. H. T.; Kong, A. K. H.; Li, K. L.

    2013-12-01

    Following an earlier report of decreased brightness in optical and X-rays, and possibly gamma-rays, of XSS J12270-4859 (ATel #5647), we provide further information based on Fermi/LAT and Swift/XRT observations of this gamma-ray emitting low-mass X-ray binary.

  4. Effectiveness and Persistence with Liraglutide Among Patients with Type 2 Diabetes in Routine Clinical Practice--EVIDENCE: A Prospective, 2-Year Follow-Up, Observational, Post-Marketing Study.

    Science.gov (United States)

    Gautier, Jean-Francois; Martinez, Luc; Penfornis, Alfred; Eschwège, Eveline; Charpentier, Guillaume; Huret, Benoît; Madani, Suliya; Gourdy, Pierre

    2015-09-01

    The aim of this study was to investigate whether the efficacy of liraglutide observed in randomized controlled trials translates into therapeutic benefits in the French population during routine clinical practice. This observational, prospective, multicenter study included 3152 adults with type 2 diabetes who had recently started or were about to start liraglutide treatment. During 2 years of follow-up, an evaluation of the reasons for prescribing liraglutide, maintenance dose of liraglutide, changes in combined antidiabetic treatments, level of glycemic control, change in body weight and body mass index (BMI), patient satisfaction with diabetes treatment and safety of liraglutide were investigated. The primary study endpoint was the proportion of patients still receiving liraglutide and presenting with HbA1c <7.0% after 2 years of follow-up. At the end of the study, 29.5% of patients maintained liraglutide treatment and reached the HbA(1c) target. Mean (±SD) HbA(1c), fasting plasma glucose concentration, body weight and BMI were significantly reduced from baseline [8.46% (±1.46) to 7.44% (±1.20); 180 (±60) to 146 (±44) mg/dL; 95.2 (±20.0) to 91.1 (±19.6) kg; 34.0 (±7.2) to 32.5 (±6.9) kg/m(2); respectively, all P < 0.0001]. Patient treatment satisfaction increased, with the mean diabetes treatment satisfaction questionnaire status version score increasing from 22.17 (±7.64) to 28.55 (±5.79), P < 0.0001. The main adverse event type was gastrointestinal, with a frequency of 10.9%, and the percentage of patients suffering ≥1 hypoglycemic episode decreased from 6.9% to 4.4%. The results of the EVIDENCE study suggest that the effectiveness of liraglutide in real-world clinical practice is similar to that observed in randomized controlled trials. Novo Nordisk A/S. ClinicalTrials.gov identifier, NCT01226966.

  5. Is the radiographic subsidence of stand-alone cages associated with adverse clinical outcomes after cervical spine fusion? An observational cohort study with 2-year follow-up outcome scoring.

    Science.gov (United States)

    Zajonz, Dirk; Franke, Anne-Catherine; von der Höh, Nicolas; Voelker, Anna; Moche, Michael; Gulow, Jens; Heyde, Christoph-Eckhard

    2014-01-01

    The stand-alone treatment of degenerative cervical spine pathologies is a proven method in clinical practice. However, its impact on subsidence, the resulting changes to the profile of the cervical spine and the possible influence of clinical results compared to treatment with additive plate osteosynthesis remain under discussion until present. This study was designed as a retrospective observational cohort study to test the hypothesis that radiographic subsidence of cervical cages is not associated with adverse clinical outcomes. 33 cervical segments were treated surgically by ACDF with stand-alone cage in 17 patients (11 female, 6 male), mean age 56 years (33-82 years), and re-examined after eight and twenty-six months (mean) by means of radiology and score assessment (Medical Outcomes Study Short Form (MOS-SF 36), Oswestry Neck Disability Index (ONDI), painDETECT questionnaire and the visual analogue scale (VAS)). Subsidence was observed in 50.5% of segments (18/33) and 70.6% of patients (12/17). 36.3% of cases of subsidence (12/33) were observed after eight months during mean time of follow-up 1. After 26 months during mean time of follow-up 2, full radiographic fusion was seen in 100%. MOS-SF 36, ONDI and VAS did not show any significant difference between cases with and without subsidence in the two-sample t-test. Only in one type of scoring (painDETECT questionnaire) did a statistically significant difference in t-Test emerge between the two groups (p = 0.03; α = 0.05). However, preoperative painDETECT score differ significantly between patients with subsidence (13.3 falling to 12.6) and patients without subsidence (7.8 dropped to 6.3). The radiological findings indicated 100% healing after stand-alone treatment with ACDF. Subsidence occurred in 50% of the segments treated. No impact on the clinical results was detected in the medium-term study period.

  6. Follow-Up Multicenter Alpha Counting Comparison

    Science.gov (United States)

    Wilkinson, J. D.; Clark, B. M.; Wong, R.; Slayman, C.; Gordon, M. S.; He, Y.; Marckmann, J.; McNally, B. D.; Wu, T.

    2014-08-01

    A follow-up alpha emissivity study was conducted to examine the wide variability observed in previous work that was hypothesized to be due to differences in the pulse height discrimination threshold among participant's equipment. Two samples, one mixed energy and one monoenergetic, were prepared and sequentially circulated to all participants for counting. Analysis of the data demonstrates that only a small portion of the variability is explained by this mechanism. The role of the sample to entrance window gap for some counters was analyzed post hoc using the same data set and may be responsible for a large amount of the variability. The results of this large-scale study demonstrate the continuing uncertainty for these measurements and the importance of interpreting their results appropriately when estimating soft error rates.

  7. Swift essentials

    CERN Document Server

    Blewitt, Alex

    2014-01-01

    Whether you are a seasoned Objective-C developer or new to the Xcode platform, Swift Essentials will provide you with all you need to know to get started with the language. Prior experience with iOS development is not necessary, but will be helpful to get the most out of the book.

  8. Follow-up interviews after eclampsia

    DEFF Research Database (Denmark)

    Andersgaard, Alice Beathe; Herbst, Andreas; Johansen, Marianne

    2008-01-01

    hundred and twenty-three women (59%) were followed up with a structured telephone interview, 6-24 months (median 11) after their eclamptic fit. Results: At the time of follow-up, 63 women (51%) had at least one persistent symptom; 2 patients had severe neurological sequels (hemiparesis and dysarthria), 11...

  9. Towards sustainability assessment follow-up

    International Nuclear Information System (INIS)

    Morrison-Saunders, Angus; Pope, Jenny; Bond, Alan; Retief, Francois

    2014-01-01

    This paper conceptualises what sustainability assessment follow-up might entail for three models of sustainability assessment: EIA-driven integrated assessment, objectives-led integrated assessment and the contribution to sustainability model. The first two are characterised by proponent monitoring and evaluation of individual impacts and indicators while the latter takes a holistic view based around focused sustainability criteria relevant to the context. The implications of three sustainability challenges on follow-up are also examined: contested time horizons and value changes, trade-offs, and interdisciplinarity. We conclude that in order to meet these challenges some form of adaptive follow-up is necessary and that the contribution to sustainability approach is the best approach. -- Highlights: • We explore sustainability follow-up for three different sustainability models. • Long-time frames require adaptive follow-up and are a key follow-up challenge. • Other key challenges include interdisciplinarity, and trade-offs. • Sustainability follow-up should be a direction of travel and not an outcome. • Only the follow-up for contribution to sustainability model addresses sustainability challenges sufficiently

  10. Follow-up in Childhood Functional Constipation

    DEFF Research Database (Denmark)

    Modin, Line; Walsted, Anne-Mette; Rittig, Charlotte Siggaard

    2016-01-01

    OBJECTIVES: Guidelines recommend close follow-up during treatment of childhood functional constipation. Only sparse evidence exists on how follow-up is best implemented. Our aim was to evaluate if follow-up by phone or self-management through web-based information improved treatment outcomes....... METHODS: In this randomized, controlled trial, conducted in secondary care, 235 children, aged 2-16 years, who fulfilled the Rome III criteria of childhood constipation, were assigned to one of three follow-up regimens: (I) control group (no scheduled contact), (II) phone group (2 scheduled phone contacts......: Improved self-management behavior caused by access to self-motivated web-based information induced faster short-term recovery during treatment of functional constipation. Patient empowerment rather than health care promoted follow-up might be a step towards more effective treatment for childhood...

  11. FERMI/LAT OBSERVATIONS OF SWIFT/BAT SEYFERT GALAXIES: ON THE CONTRIBUTION OF RADIO-QUIET ACTIVE GALACTIC NUCLEI TO THE EXTRAGALACTIC γ-RAY BACKGROUND

    International Nuclear Information System (INIS)

    Teng, Stacy H.; Mushotzky, Richard F.; Reynolds, Christopher S.; Sambruna, Rita M.; Davis, David S.

    2011-01-01

    We present the analysis of 2.1 years of Fermi Large Area Telescope (LAT) data on 491 Seyfert galaxies detected by the Swift Burst Alert Telescope (BAT) survey. Only the two nearest objects, NGC 1068 and NGC 4945, which were identified in the Fermi first year catalog, are detected. Using Swift/BAT and radio 20 cm fluxes, we define a new radio-loudness parameter R X,BAT where radio-loud objects have log R X,BAT > –4.7. Based on this parameter, only radio-loud sources are detected by Fermi/LAT. An upper limit to the flux of the undetected sources is derived to be ∼2 × 10 –11 photons cm –2 s –1 , approximately seven times lower than the observed flux of NGC 1068. Assuming a median redshift of 0.031, this implies an upper limit to the γ-ray (1-100 GeV) luminosity of ∼ 41 erg s –1 . In addition, we identified 120 new Fermi/LAT sources near the Swift/BAT Seyfert galaxies with significant Fermi/LAT detections. A majority of these objects do not have Swift/BAT counterparts, but their possible optical counterparts include blazars, flat-spectrum radio quasars, and quasars.

  12. Effectiveness and Persistence of Liraglutide Treatment Among Patients with Type 2 Diabetes Treated in Primary Care and Specialist Settings: A Subgroup Analysis from the EVIDENCE Study, a Prospective, 2-Year Follow-up, Observational, Post-Marketing Study.

    Science.gov (United States)

    Martinez, Luc; Penfornis, Alfred; Gautier, Jean-Francois; Eschwège, Eveline; Charpentier, Guillaume; Bouzidi, Amira; Gourdy, Pierre

    2017-03-01

    The objective of this subgroup analysis is to investigate the effectiveness of liraglutide in people with type 2 diabetes (T2D) treated within the primary care physician (PCP) and specialist care settings. EVIDENCE is a prospective, observational study of 3152 adults with T2D recently starting or about to start liraglutide treatment in France. We followed patients in the PCP and specialist settings for 2 years to evaluate the effectiveness of liraglutide in glycemic control and body weight reduction. Furthermore, we evaluated the changes in combined antihyperglycemic treatments, the reasons for prescribing liraglutide, patient satisfaction, and safety of liraglutide in these two treatment settings. After 2 years of follow-up, 477 out of 1209 (39.0%) of PCP and 297 out of 1398 (21.2%) of specialist-treated patients still used liraglutide and maintained the glycated hemoglobin (HbA 1c ) target of mass index (BMI) (-1.5 and -1.4 kg/m 2 ), all p < 0.0001. Reductions in HbA 1c and FPG were significantly greater among PCP- compared with specialist-treated patients, p < 0.0001 for both. Patient treatment satisfaction was also significantly increased in both cohorts. Reported gastrointestinal adverse events were less frequent among PCP-treated patients compared with specialist-treated patients (4.5% vs. 16.1%). Despite differences in demography and clinical characteristics of patients treated for T2D in PCP and specialty care, greater reduction in HbA 1c and increased glycemic control durability were observed with liraglutide in primary care, compared with specialist care. These data suggest that liraglutide treatment could benefit patients in primary care by delaying the need for further treatment intensification. ClinicalTrials.gov identifier, NCT01226966. Novo Nordisk A/S.

  13. Robotic Follow-Up for Human Exploration

    Science.gov (United States)

    Fong, Terrence; Bualat, Maria; Deans, Matthew C.; Adams, Byron; Allan, Mark; Altobelli, Martha; Bouyssounouse, Xavier; Cohen, Tamar; Flueckiger, Lorenzo; Garber, Joshua; hide

    2010-01-01

    We are studying how "robotic follow-up" can improve future planetary exploration. Robotic follow-up, which we define as augmenting human field work with subsequent robot activity, is a field exploration technique designed to increase human productivity and science return. To better understand the benefits, requirements, limitations and risks associated with this technique, we are conducting analog field tests with human and robot teams at the Haughton Crater impact structure on Devon Island, Canada. In this paper, we discuss the motivation for robotic follow-up, describe the scientific context and system design for our work, and present results and lessons learned from field testing.

  14. Audit Follow-up Tracking System (AFTS)

    Data.gov (United States)

    Office of Personnel Management — The Audit Follow-up Tracking System (AFTS) is used to track, monitor, and report on audits and open recommendations of the U.S. Office of Personnel Management (OPM)...

  15. Swift observations of V404 Cyg during the 2015 outburst: X-ray outflows from super-Eddington accretion

    Science.gov (United States)

    Motta, S. E.; Kajava, J. J. E.; Sánchez-Fernández, C.; Beardmore, A. P.; Sanna, A.; Page, K. L.; Fender, R.; Altamirano, D.; Charles, P.; Giustini, M.; Knigge, C.; Kuulkers, E.; Oates, S.; Osborne, J. P.

    2017-10-01

    The black hole (BH) binary V404 Cyg entered the outburst phase in 2015 June after 26 yr of X-ray quiescence, and with its behaviour broke the outburst evolution pattern typical of most BH binaries. We observed the entire outburst with the Swift satellite and performed time-resolved spectroscopy of its most active phase, obtaining over a thousand spectra with exposures from tens to hundreds of seconds. All the spectra can be fitted with an absorbed power-law model, which most of the time required the presence of a partial covering. A blueshifted iron-Kα line appears in 10 per cent of the spectra together with the signature of high column densities, and about 20 per cent of the spectra seem to show signatures of reflection. None of the spectra showed the unambiguous presence of soft disc-blackbody emission, while the observed bolometric flux exceeded the Eddington value in 3 per cent of the spectra. Our results can be explained assuming that the inner part of the accretion flow is inflated into a slim disc that both hides the innermost (and brightest) regions of the flow, and produces a cold, clumpy, high-density outflow that introduces the high absorption and fast spectral variability observed. We argue that the BH in V404 Cyg might have been accreting erratically or even continuously at Eddington/super-Eddington rates - thus sustaining a surrounding slim disc - while being partly or completely obscured by the inflated disc and its outflow. Hence, the largest flares produced by the source might not be accretion-driven events, but instead the effects of the unveiling of the extremely bright source hidden within the system.

  16. Seven years with the Swift Supergiant Fast X-ray Transients project

    Science.gov (United States)

    Romano, P.

    2015-09-01

    Supergiant Fast X-ray Transients (SFXTs) are HMXBs with OB supergiant companions. I review the results of the Swift SFXT project, which since 2007 has been exploiting Swift's capabilities in a systematic study of SFXTs and supergiant X-ray binaries (SGXBs) by combining follow-ups of outbursts, when detailed broad-band spectroscopy is possible, with long-term monitoring campaigns, when the out-of-outburst fainter states can be observed. This strategy has led us to measure their duty cycles as a function of luminosity, to extract their differential luminosity distributions in the soft X-ray domain, and to compare, with unprecedented detail, the X-ray variability in these different classes of sources. I also discuss the ;seventh year crisis;, the challenges that the recent Swift observations are making to the prevailing models attempting to explain the SFXT behavior.

  17. XMM-Newton and Swift Observations of WZ Sagittae: Spectral and Timing Analysis

    Science.gov (United States)

    Nucita, A. A.; Kuulkers, E.; De Paolis, F.; Mukai, K.; Ingrosso, G.; Maiolo, B. M. T.

    2014-01-01

    WZ Sagittae is the prototype object of a subclass of dwarf novae with rare and long (super)outbursts, in which a white dwarf primary accretes matter from a low mass companion. High-energy observations offer the possibility of a better understanding of the disk-accretion mechanism in WZ Sge-like binaries.

  18. Follow-up after rectal cancer

    DEFF Research Database (Denmark)

    Hovdenak Jakobsen, Ida; Juul, Therese; Bernstein, Inge

    2017-01-01

    BACKGROUND: The main treatment for non-metastatic rectal cancer (RC) is surgical resection. Late adverse effects that are highly prevalent and negatively impact patients' symptom burden and quality of life are: bowel-, urological and sexual dysfunctions; psychological distress; fear of recurrence....... As a consequence, the randomized controlled trial Follow-up after Rectal Cancer (FURCA) has been launched, testing the effect of a new patient-led, follow-up program. The aim of this paper is to describe the methodology used in the FURCA study and to report results from the development of the patient-led, follow......, or a control group following the current follow-up program with routine medicals. The primary outcomes are symptom burden and quality of life, measured by the Functional Assessment of Cancer Therapy - Colorectal (FACT-C) questionnaire. Other outcome and demographic data are collected as patient...

  19. The hard X-ray spectrum of MAXI J1820+070 observed by Swift/BAT

    Science.gov (United States)

    Del Santo, Melania; Segreto, Alberto

    2018-03-01

    We have analysed the Swift/BAT data of the new transient MAXI J1820+070 (Atel #11399,#11400, #11403, #11404, #11406, #11418, #11420, #11421, #11423,#11424, #11425, #11425) collected from 2018-03-07 00:41:07 until 2018-03-15 06:20:58.

  20. Fermi/LAT Observations of Swift/BAT Seyfert Galaxies: On the Contribution of Radio-Quiet Active Galactic Nuclei to the Extragalactic gamma-Ray Background

    Science.gov (United States)

    Teng, Stacy H.; Mushotzky, Richard F.; Sambruna, Rita M.; Davis, David S.; Reynolds, Christopher S.

    2011-01-01

    We present the analysis of 2.1 years of Fermi Large Area Telescope (LAT) data on 491 Seyfert galaxies detected by the Swift Burst Alert Telescope (BAT) survey. Only the two nearest objects, NGC 1068 and NGC 4945, which were identified in the Fermi first year catalog, are detected. Using Swift/BAT and radio 20 cm fluxes, we define a new radio-loudness parameter R(sub X,BAT) where radio-loud objects have logR(sub X,BAT) > -4.7. Based on this parameter, only radio-loud sources are detected by Fermi/LAT. An upper limit to the flux of the undetected sources is derived to be approx.2x10(exp -11) photons/sq cm/s, approximately seven times lower than the observed flux of NGC 1068. Assuming a median redshift of 0.031, this implies an upper limit to the gamma-ray (1-100 GeV) luminosity of BAT Seyfert galaxies with significant Fermi/LAT detections. A majority of these objects do not have Swift/BAT counterparts, but their possible optical counterparts include blazars, flat-spectrum radio quasars, and quasars.

  1. Internet of things and bariatric surgery follow-up: Comparative study of standard and IoT follow-up.

    Science.gov (United States)

    Vilallonga, Ramon; Lecube, Albert; Fort, José Manuel; Boleko, Maria Angeles; Hidalgo, Marta; Armengol, Manel

    2013-09-01

    Follow-up of obese patient is difficult. There is no literature related to patient follow-up that incorporates the concept of Internet of Things (IoT), use of WiFi, Internet, or portable devices for this purpose. This prospective observational study commenced in June 2011. Patients were prospectively offered to participate in the IoT study group, in which they received a WiFi scale (Withing®, Paris) that provides instant WiFi data to the patient and surgeon. Other patients were admitted to the standard follow-up group at the outpatient clinic. A total of 33 patients were included in our study (ten in the IoT group). Twelve patients did not have WiFi at home, ten lacked of computer knowledge, and seven preferred standard for follow-up. All patients underwent different surgical procedures. There were no complications. Excess weight loss (EWL) was similar in both groups. More than 90% of patients were satisfied. In the IoT group, patients considered it valuable in saving time, and considered seeing their evolution graphics extremely motivating. IoT technology can monitor medical parameters remotely and collect data. A WiFi scale can facilitate preoperative and follow-up. Standard follow-up in a classical outpatient clinic setting with the surgeon was preferred globally.

  2. Radiological follow-up of inverted papilloma

    Energy Technology Data Exchange (ETDEWEB)

    Petit, P.; Vivarrat-Perrin, L.; Champsaur, P.; Juhan, V.; Chagnaud, C.; Vidal, V.; Gaubert, J.Y.; Bartoli, J.M.; Moulin, G. [Department of Radiology, Groupe Hospitalier de la Timone, Centre Hospitalier et Universitaire de Marseille, F-13385 Marseille Cedex 5 (France); Dessi, P.; Zanaret, M. [Department of Head and Neck Surgery, Groupe Hospitalier de la Timone, Centre Hospitalier et Universitaire de Marseille, F-13385 Marseille Cedex 5 (France)

    2000-07-01

    The aim of this study was to describe cross-sectional imaging features of recurrent papilloma of the nasal fossa and paranasal sinuses and to evaluate the role of MR and CT in the postoperative follow-up of this lesion. Magnetic resonance imaging and CT of ten patients who presented recurrence of inverted papilloma were reviewed and correlated to initial imaging, endoscopy, and surgical reports. Imaging patterns of recurrent inverted papilloma are identical to those of initial tumors and recurrence location is closely related to the site of the former lesion. Magnetic resonance is more efficient than CT for the diagnosis and evaluation of extensions. Magnetic resonance supplies the deficiencies of endoscopy in case of extensions to the frontal sinus or the lateral recess of the antrum, especially if mucosal hyperplasia or sinusitis is associated. Magnetic resonance imaging is the first imaging modality to perform in the follow-up after removal of inverted papilloma. (orig.)

  3. [Follow-up after bariatric surgery].

    Science.gov (United States)

    Hofsø, Dag; Aasheim, Erlend T; Søvik, Torgeir T; Jakobsen, Gunn Signe; Johnson, Line Kristin; Sandbu, Rune; Aas, Alf Tore; Kristinsson, Jon; Hjelmesæth, Jøran

    2011-10-04

    The number of bariatric surgical procedures in Norway is increasing. Patients who undergo bariatric surgery may experience surgical, medical and nutritional complications. Follow-up of these patients is therefore important. The article is based on non-systematic literature searches in PubMed and on the clinical experience of the authors. Bariatric surgery induces significant and sustained weight loss and improves obesity-related disorders. Gastric bypass is the most commonly performed bariatric procedure in Norway. This procedure is associated with a 30-day mortality of below 0.5 %, while severe complications occur in approximately 5 % of patients. Late complications include internal herniation, intestinal ulcers and gallbladder disease. After surgery all patients are given iron, vitamin D/calcium and vitamin B12 supplements to prevent vitamin and mineral deficiencies. Gastrointestinal symptoms and postprandial hypoglycaemia after surgery can be improved by dietary modifications, and the need for anti-diabetic and blood pressure lowering medications is reduced. Dose adjustment of other medications may also be necessary. Pregnancy is not recommended during the first year after bariatric surgery. Many patients need plastic surgery after the operation. Complications after bariatric surgery may manifest in the long term. Regular follow-up is required. General practitioners should be responsible for follow-up in the long term, and should be familiar with common and serious complications as well as normal symptomatology after bariatric surgery.

  4. Follow-up of colorectal cancer patients: quality of life and attitudes towards follow-up

    NARCIS (Netherlands)

    Stiggelbout, A. M.; de Haes, J. C.; Vree, R.; van de Velde, C. J.; Bruijninckx, C. M.; van Groningen, K.; Kievit, J.

    1997-01-01

    The aims of our study were to assess the effect of follow-up on the quality of life of colorectal cancer patients and to assess the attitudes of patients towards follow-up as a function of patient characteristics. Patients who had been treated with curative intent were selected from four types of

  5. Loss of Follow-up in Orthopaedic Trauma: Who Is Getting Lost to Follow-up?

    Science.gov (United States)

    Zelle, Boris A; Buttacavoli, Frank A; Shroff, Jeffrey B; Stirton, Jacob B

    2015-11-01

    Noncompliance with postoperative follow-up visits remains a common problem in orthopaedic trauma. The aim of this study was to identify risk factors for loss of follow-up after orthopaedic trauma. Retrospective review. Urban level 1 academic trauma center. A total of 307 (226 men/81 women) patients undergoing surgical treatment of their orthopaedic injuries were included in this study. The average age was 40.4 ± 17 years. All patients were treated surgically for their orthopaedic injuries and were instructed to follow-up in the orthopaedic trauma clinic after hospital discharge. Noncompliance with follow-up appointment at 6 months after injury. Over a 6-month postoperative period, a total of 215 patients were noncompliant with at least one of their follow-up appointments between hospital discharge and the 6-month follow-up. A logistic regression showed male gender, uninsured or government insurance, and smoker to be statistically significant risk factors for noncompliance with the 6-month follow-up (P trauma. Our study suggests different risk factors for noncompliance, including male gender, smoker, lack of commercial health insurance, and illicit drug abuse. Health care providers may consider establishing protocols for facilitating follow-up appointments to patients who are at risk for noncompliance.

  6. MAGIC electromagnetic follow-up of gravitational wave alerts

    Science.gov (United States)

    de Lotto, Barbara; Ansoldi, Stefano; Antonelli, Angelo; Berti, Alessio; Carosi, Alessandro; Longo, Francesco; Stamerra, Antonio

    The year 2015 witnessed the first direct observations of a transient gravitational-wave (GW) signal from binary black hole mergers by the Advanced Laser Interferometer Gravitational-wave Observatory (aLIGO) Collaboration with the Virgo Collaboration. The MAGIC two 17m diameter Cherenkov telescopes system joined since 2014 the vast collaboration of electromagnetic facilities for follow-up of gravitational wave alerts. During the 2015 LIGO-Virgo science run we set up the procedure for GW alerts follow-up and took data following the last GW alert. MAGIC results on the data analysis and prospects for the forthcoming run are presented.

  7. Optical and X-ray early follow-up of ANTARES neutrino alerts

    Science.gov (United States)

    Adrián-Martínez, S.; Ageron, M.; Albert, A.; Samarai, I. Al; André, M.; Anton, G.; Ardid, M.; Aubert, J.-J.; Baret, B.; Barrios-Martí, J.; Basa, S.; Bertin, V.; Biagi, S.; Bogazzi, C.; Bormuth, R.; Bou-Cabo, M.; Bouwhuis, M. C.; Bruijn, R.; Brunner, J.; Busto, J.; Capone, A.; Caramete, L.; Carr, J.; Chiarusi, T.; Circella, M.; Coniglione, R.; Costantini, H.; Coyle, P.; Creusot, A.; Dekeyser, I.; Deschamps, A.; De Bonis, G.; Distefano, C.; Donzaud, C.; Dornic, D.; Drouhin, D.; Dumas, A.; Eberl, T.; Elsässer, D.; Enzenhöfer, A.; Fehn, K.; Felis, I.; Fermani, P.; Folger, F.; Fusco, L. A.; Galatà, S.; Gay, P.; Geißelsöder, S.; Geyer, K.; Giordano, V.; Gleixner, A.; Gracia-Ruiz, R.; Graf, K.; van Haren, H.; Heijboer, A. J.; Hello, Y.; Hernández-Rey, J. J.; Herrero, A.; Hößl, J.; Hofestädt, J.; Hugon, C.; James, C. W.; de Jong, M.; Kadler, M.; Kalekin, O.; Katz, U.; Kießling, D.; Kooijman, P.; Kouchner, A.; Kreykenbohm, I.; Kulikovskiy, V.; Lahmann, R.; Lambard, G.; Lattuada, D.; Lefèvre, D.; Leonora, E.; Loucatos, S.; Mangano, S.; Marcelin, M.; Margiotta, A.; Martínez-Mora, J. A.; Martini, S.; Mathieu, A.; Michael, T.; Migliozzi, P.; Moussa, A.; Mueller, C.; Neff, M.; Nezri, E.; Păvălaš, G. E.; Pellegrino, C.; Perrina, C.; Piattelli, P.; Popa, V.; Pradier, T.; Racca, C.; Riccobene, G.; Richter, R.; Roensch, K.; Rostovtsev, A.; Saldaña, M.; Samtleben, D. F. E.; Sanguineti, M.; Sapienza, P.; Schmid, J.; Schnabel, J.; Schulte, S.; Schüssler, F.; Seitz, T.; Sieger, C.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th.; Sánchez-Losa, A.; Taiuti, M.; Tamburini, C.; Trovato, A.; Tselengidou, M.; Tönnis, C.; Turpin, D.; Vallage, B.; Vallée, C.; Van Elewyck, V.; Vecchi, M.; Visser, E.; Vivolo, D.; Wagner, S.; Wilms, J.; Zornoza, J. D.; Zúñiga, J.; Klotz, A.; Boer, M.; Le Van Suu, A.; Akerlof, C.; Zheng, W.; Evans, P.; Gehrels, N.; Kennea, J.; Osborne, J. P.; Coward, D. M.

    2016-02-01

    High-energy neutrinos could be produced in the interaction of charged cosmic rays with matter or radiation surrounding astrophysical sources. Even with the recent detection of extraterrestrial high-energy neutrinos by the IceCube experiment, no astrophysical neutrino source has yet been discovered. Transient sources, such as gamma-ray bursts, core-collapse supernovae, or active galactic nuclei are promising candidates. Multi-messenger programs offer a unique opportunity to detect these transient sources. By combining the information provided by the ANTARES neutrino telescope with information coming from other observatories, the probability of detecting a source is enhanced, allowing the possibility of identifying a neutrino progenitor from a single detected event. A method based on optical and X-ray follow-ups of high-energy neutrino alerts has been developed within the ANTARES collaboration. This method does not require any assumptions on the relation between neutrino and photon spectra other than time-correlation. This program, denoted as TAToO, triggers a network of robotic optical telescopes (TAROT and ROTSE) and the Swift-XRT with a delay of only a few seconds after a neutrino detection, and is therefore well-suited to search for fast transient sources. To identify an optical or X-ray counterpart to a neutrino signal, the images provided by the follow-up observations are analysed with dedicated pipelines. A total of 42 alerts with optical and 7 alerts with X-ray images taken with a maximum delay of 24 hours after the neutrino trigger have been analysed. No optical or X-ray counterparts associated to the neutrino triggers have been found, and upper limits on transient source magnitudes have been derived. The probability to reject the gamma-ray burst origin hypothesis has been computed for each alert.

  8. Optical and X-ray early follow-up of ANTARES neutrino alerts

    International Nuclear Information System (INIS)

    Adrián-Martínez, S.; Ardid, M.; Ageron, M.; Al Samarai, I.; Aubert, J.-J.; Albert, A.; André, M.; Anton, G.; Baret, B.; Barrios-Martí, J.

    2016-01-01

    High-energy neutrinos could be produced in the interaction of charged cosmic rays with matter or radiation surrounding astrophysical sources. Even with the recent detection of extraterrestrial high-energy neutrinos by the IceCube experiment, no astrophysical neutrino source has yet been discovered. Transient sources, such as gamma-ray bursts, core-collapse supernovae, or active galactic nuclei are promising candidates. Multi-messenger programs offer a unique opportunity to detect these transient sources. By combining the information provided by the ANTARES neutrino telescope with information coming from other observatories, the probability of detecting a source is enhanced, allowing the possibility of identifying a neutrino progenitor from a single detected event. A method based on optical and X-ray follow-ups of high-energy neutrino alerts has been developed within the ANTARES collaboration. This method does not require any assumptions on the relation between neutrino and photon spectra other than time-correlation. This program, denoted as TAToO, triggers a network of robotic optical telescopes (TAROT and ROTSE) and the Swift-XRT with a delay of only a few seconds after a neutrino detection, and is therefore well-suited to search for fast transient sources. To identify an optical or X-ray counterpart to a neutrino signal, the images provided by the follow-up observations are analysed with dedicated pipelines. A total of 42 alerts with optical and 7 alerts with X-ray images taken with a maximum delay of 24 hours after the neutrino trigger have been analysed. No optical or X-ray counterparts associated to the neutrino triggers have been found, and upper limits on transient source magnitudes have been derived. The probability to reject the gamma-ray burst origin hypothesis has been computed for each alert

  9. Optical and X-Ray Early Follow-Up of ANTARES Neutrino Alerts

    Science.gov (United States)

    Adrian-Martinez, S.; Ageron, M.; Albert, A.; Samarai, I. Al; Andre, M.; Anton, G.; Ardid, M.; Aubert, J.-J.; Baret, B.; Barrios-Marti, J.; hide

    2016-01-01

    High-energy neutrinos could be produced in the interaction of charged cosmic rays with matter or radiation surrounding astrophysical sources. Even with the recent detection of extraterrestrial high-energy neutrinos by the IceCube experiment, no astrophysical neutrinosource has yet been discovered. Transient sources, such as gamma-ray bursts, core-collapse supernovae, or active galactic nuclei are promising candidates. Multi-messenger programs offer a unique opportunity to detect these transient sources. By combining the information provided by the ANTARES neutrino telescope with information coming from other observatories, the probability of detecting a source is enhanced, allowing the possibility of identifyinga neutrino progenitor from a single detected event. A method based on optical and X-ray follow-ups of high-energy neutrino alerts has been developed within the ANTARES collaboration. This method does not require any assumptions on the relation between neutrino and photon spectra other than time-correlation. This program, denoted as TAToO, triggers a network of robotic optical telescopes (TAROTand ROTSE) and the Swift-XRT with a delay of only a few seconds after a neutrino detection, and is therefore well-suited to search for fast transient sources. To identify an optical or Xraycounterpart to a neutrino signal, the images provided by the follow-up observations areanalysed with dedicated pipelines. A total of 42 alerts with optical and 7 alerts with X-ray images taken with a maximum delay of 24 hours after the neutrino trigger have been analyzed. No optical or X-ray counterparts associated to the neutrino triggers have been found, and upper limits on transient source magnitudes have been derived. The probability to reject the gamma-ray burst origin hypothesis has been computed for each alert.

  10. Diverse Long-term Variability of Five Candidate High-mass X-Ray Binaries from Swift Burst Alert Telescope Observations

    Energy Technology Data Exchange (ETDEWEB)

    Corbet, Robin H. D. [University of Maryland, Baltimore County, MD 21250 (United States); Coley, Joel B. [NASA Postdoctoral Program, and Astroparticle Physics Laboratory, Code 661 NASA Goddard Space Flight Center, Greenbelt Road, MD 20771 (United States); Krimm, Hans A., E-mail: corbet@umbc.edu [Universities Space Research Association, 10211 Wincopin Circle, Suite 500, Columbia, MD 21044 (United States)

    2017-09-10

    We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope. IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with the Swift X-ray Telescope show a hint of pulsations at 33.4 s. For AX J1700.2-4220, 54 s pulsations were previously found with XMM-Newton . Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090, which was previously proposed to be a Be star system with an orbital period of ∼30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although they might be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be star mass donors.

  11. Swift follow-up of 1RXS J194211.9+255552

    DEFF Research Database (Denmark)

    Sidoli, L.; Fiocchi, M.; Bird, A. J.

    2011-01-01

    there is only one pointlike source, at the following position (J2000): RA(hh mm ss.s) = 19h42m11.13s, Dec(dd mm ss.s) = +25:56:07.32 (3.6 arcsec error radius). The source light curve is variable on time scale of about 1000 s (similar to the Jem-X light curve). A fit to the XRT spectrum (1-10 keV) with a power...... law model resulted in a good fit (reduced chi_sq = 1.101 for 36 degrees of freedom) with an absorption of NH = 1.28E22 cm-2 (+0.57, -0.52) (consistent with the total Galactic value), a photon index of 0.64 (+0.30, -0.28) and an unabsorbed flux (1-10 keV) of 7.88E-11 ergs/cm2/s. A black body model...... resulted in a much worse fit (reduced chi_sq = 1.367 for 36 dof). The source is a factor of 2.5 fainter than during the Jem-X detection (ATel #3816), two days before. This is the first characterization of the source X-ray spectrum. A search at other wavelengths resulted in a possible counterpart in the 2...

  12. [Allogeneic parathyroid: 2-year follow-up].

    Science.gov (United States)

    Hermosillo-Sandoval, José Manuel; Leonher-Ruezga, Karla Lisseth; Jiménez-Gómez, José Alfredo; Fuentes-Orozco, Clotilde; González-Ojeda, Alejandro; Ramírez-González, Luis Ricardo

    2015-01-01

    Hypoparathyroidism is one of the most frequent complications of neck surgery. The treatment is currently medical; however this involves several complications secondary to high doses of calcium and vitamin D, thus making parathyroid allotransplantation a good management option. Patients with hypoparathyroidism were selected in the April-December period of 2011 in the general surgical clinic. They were between 16 and 65 years, and ingested high doses of calcium. The donors were patients with primary and secondary hyperparathyroidism, and the transplants were performed in relation to blood group and human leucocyte antigen. Five parathyroid allografts were performed. All the patients had iatrogenic hypoparathyroidism, all women with a mean age of 49.8 years. The graft was implanted under local anaesthesia in the non-dominant forearm. Four of the patients are so far considered functional due to the increase in paratohormone, and demonstrating its function by scintigraphy with sestamibi. One of the patients showed no increase in paratohormone or imaging studies that demonstrate its functionality. After a two year follow up the graft remains functional but with with oral calcium intake at a lower dose than before transplantation. None of the patients had immunosuppression side effects. In this study, allogeneic unrelated living parathyroid transplant with an immunosuppressive regimen of six months has proven to be a safe alternative treatment to improve quality of life by decreasing the excessive calcium intake and improving physical activity with adequate graft survival at 24 months follow up. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  13. Esophageal atresia: long-term interdisciplinary follow-up

    Directory of Open Access Journals (Sweden)

    Lidia B. Giúdici

    2016-07-01

    Full Text Available Background: We provide protocolized interdisciplinary follow-up to babies born with Esophageal Atresia (EA. There are few reports in Argentina about follow-up of EA patients.Objective: To describe outcomes in follow-up of EA patients at 1, 3 and 6 years old and to compare outcomes at age 1 with those at age 6.Methods: Prospective, longitudinal, analytic study of the cohort of babies born with EA, admitted to the follow-up program from 11/01/03 to 10/31/14. Follow-up includes: growth (weight > 10th centile, WHO, neurology-psychomotor development, audiology, vision, genetic, mental health, surgical reintervention, phonostomatology, language, pulmonology, re-hospitalization for clinical causes, lost to follow-up. Outcomes were described at age 1, 3 and 6. We included all EA patients who had reached age 1 at the start of this study.Results: 27 babies were admitted; 30% had long-gap EA; 18% presented VACTERL association; 23 children met inclusion criteria. Genetics  was assessed in 18 newborns (78%; a chromosomal map was performed in 11 babies; 3 had an abnormal karyotype. Mental health: 5/14 of the assessed children showed problems. Phonostomatology: 11 newborns checked (6 required treatment, 4 recovered at age 1. Pulmonologist evaluated 18 babies (7 with recurrent wheezing, 6 with moderate tracheomalacia. Gastroenterology and endoscopy: 80% presented gastroesophageal reflux (GER grade 3-4, and 50% showed a pathologic pHmetry. Lost to follow-up: age 1, 2 (8%; age 3, 3 (17%; age 6, 3 (23%. Normal outcomes observed are the following. Age 1 – growth: 81%; neurologic-psychomotor developmental index (NPDI: 76%; audiology: 95%; vision: 85%; language: 62%; re-hospitalization for clinical causes: 38%; surgical reinterventions: 47%. Age 3 – growth: 78%; NPDI: 50%; audiology: 93%; vision: 93%; language: 43%; re-hospitalization: 35%; surgical reinterventions: 14%. Age 6 – growth: 50%; NPDI: 30%; audiology: 90%; vision: 40%; language: 50%; re

  14. Suzaku  Observations of Heavily Obscured (Compton-thick) Active Galactic Nuclei Selected by the Swift/BAT Hard X-Ray Survey

    Science.gov (United States)

    Tanimoto, Atsushi; Ueda, Yoshihiro; Kawamuro, Taiki; Ricci, Claudio; Awaki, Hisamitsu; Terashima, Yuichi

    2018-02-01

    We present a uniform broadband X-ray (0.5–100.0 keV) spectral analysis of 12 Swift/Burst Alert Telescope selected Compton-thick ({log}{N}{{H}}/{{cm}}-2≥slant 24) active galactic nuclei (CTAGNs) observed with Suzaku. The Suzaku data of three objects are published here for the first time. We fit the Suzaku and Swift spectra with models utilizing an analytic reflection code and those utilizing the Monte-Carlo-based model from an AGN torus by Ikeda et al. The main results are as follows: (1) The estimated intrinsic luminosity of a CTAGN strongly depends on the model; applying Compton scattering to the transmitted component in an analytic model may largely overestimate the intrinsic luminosity at large column densities. (2) Unabsorbed reflection components are commonly observed, suggesting that the tori are clumpy. (3) Most of CTAGNs show small scattering fractions (<0.5%), implying a buried AGN nature. (4) Comparison with the results obtained for Compton-thin AGNs suggests that the properties of these CTAGNs can be understood as a smooth extension from Compton-thin AGNs with heavier obscuration; we find no evidence that the bulk of the population of hard-X-ray-selected CTAGNs are different from less obscured objects.

  15. Morbidity follow-up feasibility study

    International Nuclear Information System (INIS)

    Carpenter, M.

    1988-02-01

    The report reviews the available sources of data within Canada for undertaking morbidity follow-up studies to both supplement and complement studies using Canadian mortality data. Such studies would permit earlier detection and more sensitive measures of differences in risk for exposures to radiation and allow timely measures to be taken to minimize any occupational and environmental health risk to radiation workers. The technical feasibility of using these sources was reviewed using the criteria of adequate personal identifying information, automation of data records, file size and the accuracy of the morbidity diagnosis information. At the present time certain of the provincial cancer registry files meet these criteria best. A work plan was prepared suggesting a morbidity pilot study to clarify the role of occupational factors in the incidence of cancer among radiation workers using the Alberta Cancer Registry file and the National Dose Registry (NDR) file of radiation workers. For the longer term a full cohort study using the National Cancer Incidence Reporting System (NCIRS) and the NDR workers as the study population would provide information on all radiation workers on a national basis. A work plan was prepared and some initial format conversion of historical data was undertaken to begin developing the NCIRS into a data base suitable for long-term health studies

  16. Swift for dummies

    CERN Document Server

    Feiler, Jesse

    2015-01-01

    Get up and running with Swift-swiftly Brimming with expert advice and easy-to-follow instructions,Swift For Dummies shows new and existing programmers how toquickly port existing Objective-C applications into Swift and getinto the swing of the new language like a pro. Designed from theground up to be a simpler programming language, it's never beeneasier to get started creating apps for the iPhone or iPad, orapplications for Mac OS X. Inside the book, you'll find out how to set up Xcode for a newSwift application, use operators, objects, and data types, andcontrol program flow with conditiona

  17. Serial extraction: 20 years of follow-up

    OpenAIRE

    Almeida,Renato Rodrigues de; Almeida,Marcio Rodrigues de; Oltramari-Navarro,Paula Vanessa Pedron; Conti,Ana Cláudia de Castro Ferreira; Navarro,Ricardo de Lima; Souza,Karen Regina Siqueira de

    2012-01-01

    This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been re...

  18. THE SWIFT AGN AND CLUSTER SURVEY. II. CLUSTER CONFIRMATION WITH SDSS DATA

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, Rhiannon D.; Dai, Xinyu [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, Norman, OK 73019 (United States); Kochanek, Christopher S. [Department of Astronomy, Ohio State University, Columbus, OH 43210 (United States); Bregman, Joel N., E-mail: Rhiannon.D.Griffin-1@ou.edu, E-mail: xdai@ou.edu, E-mail: ckochanek@astronomy.ohio-state.edu, E-mail: jbregman@umich.edu [Department of Astronomy, University of Michigan, Ann Arbor, MI 48109 (United States)

    2016-01-15

    We study 203 (of 442) Swift AGN and Cluster Survey extended X-ray sources located in the SDSS DR8 footprint to search for galaxy over-densities in three-dimensional space using SDSS galaxy photometric redshifts and positions near the Swift cluster candidates. We find 104 Swift clusters with a >3σ galaxy over-density. The remaining targets are potentially located at higher redshifts and require deeper optical follow-up observations for confirmation as galaxy clusters. We present a series of cluster properties including the redshift, brightest cluster galaxy (BCG) magnitude, BCG-to-X-ray center offset, optical richness, and X-ray luminosity. We also detect red sequences in ∼85% of the 104 confirmed clusters. The X-ray luminosity and optical richness for the SDSS confirmed Swift clusters are correlated and follow previously established relations. The distribution of the separations between the X-ray centroids and the most likely BCG is also consistent with expectation. We compare the observed redshift distribution of the sample with a theoretical model, and find that our sample is complete for z ≲ 0.3 and is still 80% complete up to z ≃ 0.4, consistent with the SDSS survey depth. These analysis results suggest that our Swift cluster selection algorithm has yielded a statistically well-defined cluster sample for further study of cluster evolution and cosmology. We also match our SDSS confirmed Swift clusters to existing cluster catalogs, and find 42, 23, and 1 matches in optical, X-ray, and Sunyaev–Zel’dovich catalogs, respectively, and so the majority of these clusters are new detections.

  19. LATE TIME MULTI-WAVELENGTH OBSERVATIONS OF SWIFT J1644+5734: A LUMINOUS OPTICAL/IR BUMP AND QUIESCENT X-RAY EMISSION

    Energy Technology Data Exchange (ETDEWEB)

    Levan, A. J.; Brown, G. C.; Lyman, J. D.; Stanway, E. R. [Department of Physics, University of Warwick, Coventry, CV4 7AL (United Kingdom); Tanvir, N. R.; Page, K. L.; O’Brien, P. T.; Wiersema, K. [Department of Physics and Astronomy, University of Leicester, Leicester, LE1 7RH (United Kingdom); Metzger, B. D. [Columbia Astrophysics Laboratory, New York, NY 10027 (United States); Cenko, S. B. [Astrophysics Science Division, NASA Goddard Space Flight Center, Mail Code 661, Greenbelt, MD 20771 (United States); Fruchter, A. S. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Perley, D. A. [Department of Astronomy, California Institute of Technology, MC 249-17, 1200 East California Boulevard, Pasadena, CA 91125 (United States); Bloom, J. S., E-mail: A.J.Levan@warwick.ac.uk [Astronomy Department, University of California, Berkeley, CA 94720-7450 (United States)

    2016-03-01

    We present late time multi-wavelength observations of Swift J1644+57, suggested to be a relativistic tidal disruption flare (TDF). Our observations extend to >4 years from discovery and show that 1.4 years after outburst the relativistic jet switched off on a timescale less than tens of days, corresponding to a power-law decay faster than t{sup −70}. Beyond this point weak X-rays continue to be detected at an approximately constant luminosity of L{sub X} ∼ 5 × 10{sup 42} erg s{sup −1} and are marginally inconsistent with a continuing decay of t{sup −5/3}, similar to that seen prior to the switch-off. Host photometry enables us to infer a black hole mass of M{sub BH} = 3 × 10{sup 6} M{sub ⊙}, consistent with the late time X-ray luminosity arising from sub-Eddington accretion onto the black hole in the form of either an unusually optically faint active galactic nucleus or a slowly varying phase of the transient. Optical/IR observations show a clear bump in the light curve at timescales of 30–50 days, with a peak magnitude (corrected for host galaxy extinction) of M{sub R} ∼ −22 to −23. The luminosity of the bump is significantly higher than seen in other, non-relativistic TDFs and does not match any re-brightening seen at X-ray or radio wavelengths. Its luminosity, light curve shape, and spectrum are broadly similar to those seen in superluminous supervnovae, although subject to large uncertainties in the correction of the significant host extinction. We discuss these observations in the context of both TDF and massive star origins for Swift J1644+5734 and other candidate relativistic tidal flares.

  20. Trismus-pseudocamptodactyly syndrome: a 20 year follow-up.

    Science.gov (United States)

    Marianetti, T M; Dall'Asta, L; Torroni, A; Gasparini, G; Pelo, S

    2014-07-01

    Trismus-Pseudocamptodactyly Syndrome (TPS) is a rare autosomal syndrome characterised by the inability to open the mouth fully, pseudocamptodactyly, short stature and foot deformities. The maxillofacial feature entails hyperplasia of the coronoid processes which mechanically interfere with the zygomatic processes during mouth opening. A 22-year- old girl affected by a severe form of TPS was followed from the age of three years. Bone reossification was observed after two coronoidotomies of both hyperplasic coronoid processes. After the decision to perform a coronoidectomy, the four-year follow-up showed a favourable outcome. Meanwhile the patient developed an anterior open bite which was treated with a fourth orthognathic surgery. The follow-up underscores how the correction of malformation leads to the generation of EMG activity of the masticatory muscles after many years of passiveness.

  1. Radiographic follow-up study of Little Leaguer's shoulder.

    Science.gov (United States)

    Kanematsu, Yoshiji; Matsuura, Tetsuya; Kashiwaguchi, Shinji; Iwase, Takenobu; Suzue, Naoto; Iwame, Toshiyuki; Sairyo, Koichi

    2015-01-01

    Little Leaguer's shoulder is a syndrome involving the proximal humeral epiphyseal plate. Conservative treatment usually resolves the symptoms. However, there are no reports of a radiographic follow-up study of this disease. The purpose of this study was to show the radiographic healing process of Little Leaguer's shoulder. A total of 19 male baseball players diagnosed as having Little Leaguer's shoulder were retrospectively evaluated. The mean age at first presentation was 12.7 years. External rotation anteroposterior radiographs of the shoulder were taken. All patients were treated with rest from throwing, and no throwing was recommended until remodeling was confirmed. Follow-up radiographs were taken at 1-month intervals to assess healing. All patients were observed until healing was confirmed radiographically, after which they returned to baseball. The mean follow-up period was 8.5 months. In addition to radiography, patients were asked whether they had any symptoms and whether they had been able to return to baseball. At the first examination, radiographs showed a wider epiphyseal plate of the throwing side compared with the asymptomatic contralateral shoulder. Healing was observed in all cases. Healing occurred first along the medial side and was then extended laterally. The mean time required for healing was 4.7 months. All patients were able to return to playing baseball at their pre-injury level of play and were asymptomatic when examined at the final follow-up. The healing process of Little Leaguer's shoulder advanced from medial to lateral, and healing was achieved about 5 months after initial examination.

  2. Follow-Up Photometry of Kelt Transiting Planet Candidates

    Science.gov (United States)

    Stephens, Denise C.; Joner, Michael D.; Hintz, Eric G.; Martin, Trevor; Spencer, Alex; Kelt Follow-Up Network (FUN) Team

    2017-10-01

    We have three telescopes at BYU that we use to follow-up possible transiting planet canidates for the KELT team. These telescopes were used to collect data on Kelt-16b and Kelt-9b, which is the hottest known exoplanet. More recently we used the newest of these telescopes, a robotic 8-inch telescope on the roof of our building, to confirm the most recent Kelt planet that will be published soon. This research has been ideal for the teaching and training of undergraduate students in the art of photometric observing and data reduction. In this presentation I will highlight how we are using our membership in the Kelt team to further the educational objective of our undergraduate astronomy program, while contributing meaningful science to the ever growing field of exoplanet discovery. I will also highlight a few of the more interesting Kelt planets and the minimum telescope requirements for detecting these planets. I will then discuss the sensitivities required to follow-up future TESS candidates, which may be of interest to others interested in joining the TESS follow-up teams.

  3. A complete sample of long bright Swift gamma ray bursts.

    Science.gov (United States)

    Tagliaferri, Gianpiero; Salvaterra, Ruben; Campana, Sergio; Covino, Stefano; D'Avanzo, Paolo; Fugazza, Dino; Ghirlanda, Giancarlo; Ghisellini, Gabriele; Melandri, Andrea; Nava, Lara; Sbarufatti, Boris; Vergani, Susanna

    2013-06-13

    Complete samples are the basis of any population study. To this end, we selected a complete subsample of Swift long bright gamma ray bursts (GRBs). The sample, made up of 58 bursts, was selected by considering bursts with favourable observing conditions for ground-based follow-up observations and with the 15-150 keV 1 s peak flux above a flux threshold of 2.6 photons cm(-2) s(-1). This sample has a redshift completeness level higher than 90 per cent. Using this complete sample, we investigate the properties of long GRBs and their evolution with cosmic time, focusing in particular on the GRB luminosity function, the prompt emission spectral-energy correlations and the nature of dark bursts.

  4. Lord of the Rings - Return of the King: Swift-XRT observations of dust scattering rings around V404 Cygni

    Science.gov (United States)

    Beardmore, A. P.; Willingale, R.; Kuulkers, E.; Altamirano, D.; Motta, S. E.; Osborne, J. P.; Page, K. L.; Sivakoff, G. R.

    2016-10-01

    On 2015 June 15, the black hole X-ray binary V404 Cygni went into outburst, exhibiting extreme X-ray variability which culminated in a final flare on June 26. Over the following days, the Swift-X-ray Telescope detected a series of bright rings, comprising five main components that expanded and faded with time, caused by X-rays scattered from the otherwise unobservable dust layers in the interstellar medium in the direction of the source. Simple geometrical modelling of the rings' angular evolution reveals that they have a common temporal origin, coincident with the final, brightest flare seen by INTEGRAL's JEM X-1, which reached a 3-10 keV flux of ˜25 Crab. The high quality of the data allows the dust properties and density distribution along the line of sight to the source to be estimated. Using the Rayleigh-Gans approximation for the dust scattering cross-section and a power-law distribution of grain sizes a, ∝ a-q, the average dust emission is well modelled by q = 3.90^{+0.09}_{-0.08} and maximum grain size of a_+ = 0.147^{+0.024}_{-0.004} { μ m}, though significant variations in q are seen between the rings. The recovered dust density distribution shows five peaks associated with the dense sheets responsible for the rings at distances ranging from 1.19 to 2.13 kpc, with thicknesses of ˜40-80 pc and a maximum density occurring at the location of the nearest sheet. We find a dust column density of Ndust ≈ (2.0-2.5) × 1011 cm-2, consistent with the optical extinction to the source. Comparison of the inner rings' azimuthal X-ray evolution with archival Wide-field Infrared Survey Explorer mid-IR data suggests that the second most distant ring follows the general IR emission trend, which increases in brightness towards the Galactic north side of the source.

  5. Klenot Project - Near Earth Objects Follow-Up Program

    Science.gov (United States)

    Tichý, Miloš; Tichá, Jana; Kočer, Michal

    2016-01-01

    NEO research is a great challenge just now - for science, for exploration and for planetary defence. Therefore NEO discoveries, astrometric follow-up, orbit computations as well as physical studies are of high interest both to science community and humankind. The KLENOT Project of the Klet Observatory, South Bohemia, Czech Republic pursued the confirmation, early follow-up, long-arc follow-up and recovery of Near Earth Objects since 2002. Tens of thousands astrometric measurements helped to make inventory of NEOs as well as to understand the NEO population. It ranked among the world most prolific professional NEO follow-up programmes during its first phase from 2002 to 2008. The fundamental improvement of the 1.06-m KLENOT Telescope was started in autumn 2008. The new computer controlled paralactic mount was built to substantially increase telescope-time efficiency, the number of observations, their accuracy and limiting magnitude. The testing observations of the KLENOT Telescope Next Generation (NG) were started in October 2011. The new more efficient CCD camera FLI ProLine 230 was installed in summer 2013. The original Klet Software Package has been continually upgraded over the past two decades of operation. Along with huge hardware changes we have decided for essential changes in software and the whole KLENOT work-flow. Using the current higher computing power available, enhancing and updating our databases and astrometry program, the core of our software package, will prove highly beneficial. Moreover, the UCAC4 as the more precise astrometric star catalog was implemented. The modernized KLENOT System was put into full operation in September 2013. This step opens new possibilities for the KLENOT Project, the long-term European Contribution to Monitoring and Cataloging Near Earth Objects. KLENOT Project Goals are confirmatory observations of newly discovered fainter NEO candidates, early follow-up of newly discovered NEOs, long-arc follow-up astrometry of NEOs

  6. Meeting increased demand for total knee replacement and follow-up: determining optimal follow-up.

    Science.gov (United States)

    Meding, J B; Ritter, M A; Davis, K E; Farris, A

    2013-11-01

    The strain on clinic and surgeon resources resulting from a rise in demand for total knee replacement (TKR) requires reconsideration of when and how often patients need to be seen for follow-up. Surgeons will otherwise require increased paramedical staff or need to limit the number of TKRs they undertake. We reviewed the outcome data of 16 414 primary TKRs undertaken at our centre to determine the time to re-operation for any reason and for specific failure mechanisms. Peak risk years for failure were determined by comparing the conditional probability of failure, the number of failures divided by the total number of TKRs cases, for each year. The median times to failure for the most common failure mechanisms were 4.9 years (interquartile range (IQR) 1.7 to 10.7) for femoral and tibial loosening, 1.9 years (IQR 0.8 to 3.9) for infection, 3.1 years (IQR 1.6 to 5.5) for tibial collapse and 5.6 years (IQR 3.4 to 9.3) for instability. The median time to failure for all revisions was 3.3 years (IQR 1.2 to 8.5), with an overall revision rate of 1.7% (n = 282). Results from our patient population suggest that patients be seen for follow-up at six months, one year, three years, eight years, 12 years, and every five years thereafter. Patients with higher pain in the early post-operative period or high body mass index (≥ 41 kg/m(2)) should be monitored more closely.

  7. Serial extraction: 20 years of follow-up

    Directory of Open Access Journals (Sweden)

    Renato Rodrigues de Almeida

    2012-08-01

    Full Text Available This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program, and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment.

  8. Serial extraction: 20 years of follow-up.

    Science.gov (United States)

    Almeida, Renato Rodrigues de; Almeida, Marcio Rodrigues de; Oltramari-Navarro, Paula Vanessa Pedron; Conti, Ana Cláudia de Castro Ferreira; Navarro, Ricardo de Lima; Souza, Karen Regina Siqueira de

    2012-01-01

    This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment.

  9. Serial extraction: 20 years of follow-up

    Science.gov (United States)

    de ALMEIDA, Renato Rodrigues; de ALMEIDA, Marcio Rodrigues; OLTRAMARI-NAVARRO, Paula Vanessa Pedron; CONTI, Ana Cláudia de Castro Ferreira; NAVARRO, Ricardo de Lima; de SOUZA, Karen Regina Siqueira

    2012-01-01

    This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment. PMID:23032213

  10. Phase-resolved NuSTAR and SWIFT-XRT observations of magnetar 4U 0142+61

    DEFF Research Database (Denmark)

    Tendulkar, Shriharsh P.; Hascöet, Romain; Yang, Chengwei

    2015-01-01

    a value of ≈20%, similar to that observed in 1E 1841-045 and much lower than the ≈80% pulse fraction observed in 1E 2259+586. We do not detect the 55 ks phase modulation reported in previous Suzaku-HXD observations. The phase-averaged spectrum of 4U 0142+61 above 20 keV is dominated by a hard power law...

  11. Beginning Swift programming

    CERN Document Server

    Lee, Wei-Meng

    2014-01-01

    Enter the Swift future of iOS and OS X programming Beginning Swift Programming is your ideal starting point for creating Mac, iPhone, and iPad apps using Apple's new Swift programming language. Written by an experienced Apple developer and trainer, this comprehensive guide explains everything you need to know to jumpstart the creation of your app idea. Coverage includes data types, strings and characters, operators and functions, arrays and dictionaries, control flow, and looping, with expert guidance on classes, objects, class inheritance, closures, protocols, and generics. This succinct - ye

  12. SUBMILLIMETER FOLLOW-UP OF WISE-SELECTED HYPERLUMINOUS GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Wu Jingwen; Eisenhardt, Peter R. M.; Stern, Daniel; Assef, Roberto [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Tsai, Chao-Wei; Cutri, Roc; Griffith, Roger; Jarrett, Thomas [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Sayers, Jack; Bridge, Carrie [Division of Physics, Math and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Benford, Dominic [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Blain, Andrew [Department of Physics and Astronomy, University of Leicester, LE1 7RH Leicester (United Kingdom); Petty, Sara; Lake, Sean [Department of Physics and Astronomy, University of California Los Angeles, Los Angeles, CA 90095 (United States); Bussmann, Shane [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, MS78, Cambridge, MA 02138 (United States); Comerford, Julia M.; Evans, Neal J. II [Department of Astronomy, University of Texas, Austin, TX 78731 (United States); Lonsdale, Carol [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Rho, Jeonghee [SETI Institute, 189 BERNARDO Avenue, Mountain View, CA 94043 (United States); Stanford, S. Adam, E-mail: jingwen.wu@jpl.nasa.gov [Department of Physics, University of California Davis, One Shields Avenue, Davis, CA 95616 (United States); and others

    2012-09-01

    We have used the Caltech Submillimeter Observatory (CSO) to follow-up a sample of Wide-field Infrared Survey Explorer (WISE) selected, hyperluminous galaxies, the so-called W1W2-dropout galaxies. This is a rare ({approx}1000 all-sky) population of galaxies at high redshift (peaks at z = 2-3), which are faint or undetected by WISE at 3.4 and 4.6 {mu}m, yet are clearly detected at 12 and 22 {mu}m. The optical spectra of most of these galaxies show significant active galactic nucleus activity. We observed 14 high-redshift (z > 1.7) W1W2-dropout galaxies with SHARC-II at 350-850 {mu}m, with nine detections, and observed 18 with Bolocam at 1.1 mm, with five detections. Warm Spitzer follow-up of 25 targets at 3.6 and 4.5 {mu}m, as well as optical spectra of 12 targets, are also presented in the paper. Combining WISE data with observations from warm Spitzer and CSO, we constructed their mid-IR to millimeter spectral energy distributions (SEDs). These SEDs have a consistent shape, showing significantly higher mid-IR to submillimeter ratios than other galaxy templates, suggesting a hotter dust temperature. We estimate their dust temperatures to be 60-120 K using a single-temperature model. Their infrared luminosities are well over 10{sup 13} L{sub Sun }. These SEDs are not well fitted with existing galaxy templates, suggesting they are a new population with very high luminosity and hot dust. They are likely among the most luminous galaxies in the universe. We argue that they are extreme cases of luminous, hot dust-obscured galaxies (DOGs), possibly representing a short evolutionary phase during galaxy merging and evolution. A better understanding of their long-wavelength properties needs ALMA as well as Herschel data.

  13. Submillimeter Follow-Up of WISE-Selected Hyperluminous Galaxies

    Science.gov (United States)

    Wu, Jingwen; Tsai, Chao-Wei; Sayers, Jack; Benford, Dominic; Bridge, Carrie; Blain, Andrew; Eisenhardt, Peter R.; Stern, Daniel; Petty, Sara; Assef, Roberto; hide

    2012-01-01

    We have used the Caltech Submillimeter Observatory (CSO) to follow-up a sample of Wide-field Infrared Survey Explorer (WISE) selected, hyperluminous galaxies, the so-called W1W2-dropout galaxies. This is a rare (approx.1000 all-sky) population of galaxies at high redshift (peaks at z = 2-3), which are faint or undetected by WISE at 3.4 and 4.6 microns, yet are clearly detected at 12 and 22 microns. The optical spectra of most of these galaxies show significant active galactic nucleus activity. We observed 14 high-redshift (z > 1.7) W1W2-dropout galaxies with SHARC-II at 350-850 microns, with nine detections, and observed 18 with Bolocam at 1.1 mm, with five detections. Warm Spitzer follow-up of 25 targets at 3.6 and 4.5 microns, as well as optical spectra of 12 targets, are also presented in the paper. Combining WISE data with observations from warm Spitzer and CSO, we constructed their mid-IR to millimeter spectral energy distributions (SEDs). These SEDs have a consistent shape, showing significantly higher mid-IR to submillimeter ratios than other galaxy templates, suggesting a hotter dust temperature.We estimate their dust temperatures to be 60 C120 K using a single-temperature model. Their infrared luminosities are well over 10(exp 13) Stellar Luminosity. These SEDs are not well fitted with existing galaxy templates, suggesting they are a new population with very high luminosity and hot dust. They are likely among the most luminous galaxies in the universe.We argue that they are extreme cases of luminous, hot dust-obscured galaxies (DOGs), possibly representing a short evolutionary phase during galaxy merging and evolution. A better understanding of their long-wavelength properties needs ALMA as well as Herschel data.

  14. SUBMILLIMETER FOLLOW-UP OF WISE-SELECTED HYPERLUMINOUS GALAXIES

    International Nuclear Information System (INIS)

    Wu Jingwen; Eisenhardt, Peter R. M.; Stern, Daniel; Assef, Roberto; Tsai, Chao-Wei; Cutri, Roc; Griffith, Roger; Jarrett, Thomas; Sayers, Jack; Bridge, Carrie; Benford, Dominic; Blain, Andrew; Petty, Sara; Lake, Sean; Bussmann, Shane; Comerford, Julia M.; Evans, Neal J. II; Lonsdale, Carol; Rho, Jeonghee; Stanford, S. Adam

    2012-01-01

    We have used the Caltech Submillimeter Observatory (CSO) to follow-up a sample of Wide-field Infrared Survey Explorer (WISE) selected, hyperluminous galaxies, the so-called W1W2-dropout galaxies. This is a rare (∼1000 all-sky) population of galaxies at high redshift (peaks at z = 2-3), which are faint or undetected by WISE at 3.4 and 4.6 μm, yet are clearly detected at 12 and 22 μm. The optical spectra of most of these galaxies show significant active galactic nucleus activity. We observed 14 high-redshift (z > 1.7) W1W2-dropout galaxies with SHARC-II at 350-850 μm, with nine detections, and observed 18 with Bolocam at 1.1 mm, with five detections. Warm Spitzer follow-up of 25 targets at 3.6 and 4.5 μm, as well as optical spectra of 12 targets, are also presented in the paper. Combining WISE data with observations from warm Spitzer and CSO, we constructed their mid-IR to millimeter spectral energy distributions (SEDs). These SEDs have a consistent shape, showing significantly higher mid-IR to submillimeter ratios than other galaxy templates, suggesting a hotter dust temperature. We estimate their dust temperatures to be 60-120 K using a single-temperature model. Their infrared luminosities are well over 10 13 L ☉ . These SEDs are not well fitted with existing galaxy templates, suggesting they are a new population with very high luminosity and hot dust. They are likely among the most luminous galaxies in the universe. We argue that they are extreme cases of luminous, hot dust-obscured galaxies (DOGs), possibly representing a short evolutionary phase during galaxy merging and evolution. A better understanding of their long-wavelength properties needs ALMA as well as Herschel data.

  15. Epidemiological follow-up study of Japanese Thorotrast cases

    International Nuclear Information System (INIS)

    Mori, T.; Maruyama, T.; Kato, Y.; Takahashi, S.

    1979-01-01

    The authors conducted a follow-up study on 243 Thorotrast-administered war-wounded ex-servicemen in 1975, after a lapse of 30 to 38 years from Thorotrast injections, and found 18 cases of malignant hepatic tumor, 15 cases of other malignant tumors, 2 cases of blood diseases, and 9 cases of liver cirrhosis in 224 cases who had been given Thorotrast intravascularly. The incidence of hepatic and other malignant tumors, blood diseases, and liver cirrhosis was significantly higher than in the controls. The total number of deaths in the Thorotrast-administered cases was also significantly higher than in the controls. In the remaining 19 cases who had been given Thorotrast by a route other than intravascularly, no fatal case related to Thorotrast administration was discovered. In the living cases, however, one sarcoma was observed to have developed at the site of the Thorotrast injection

  16. GREEN BANK TELESCOPE AND SWIFT X-RAY TELESCOPE OBSERVATIONS OF THE GALACTIC CENTER RADIO MAGNETAR SGR J1745–2900

    Energy Technology Data Exchange (ETDEWEB)

    Lynch, Ryan S.; Archibald, Robert F.; Kaspi, Victoria M.; Scholz, Paul, E-mail: rlynch@physics.mcgill.ca [Department of Physics, McGill University, 3600 University Street, Montreal, Quebec, H3A 2T8 (Canada)

    2015-06-20

    We present results from eight months of Green Bank Telescope 8.7 GHz observations and nearly 18 months of Swift X-ray telescope observations of the radio magnetar SGR J1745–2900. We tracked the radio and X-ray flux density, polarization properties, profile evolution, rotation, and single-pulse behavior. We identified two main periods of activity. The first is characterized by approximately 5.5 months of relatively stable evolution in radio flux density, rotation, and profile shape, while in the second these properties varied substantially. Specifically, a third profile component emerged and the radio flux also became more variable. The single pulse properties also changed, most notably with a larger fraction of pulses with pulse widths ∼5–20 ms in the erratic state. Bright single pulses are well described by a log-normal energy distribution at low energies, but with an excess at high energies. The 2–10 keV flux decayed steadily since the initial X-ray outburst, while the radio flux remained stable to within ∼20% during the stable state. A joint pulsar timing analysis of the radio and X-ray data shows a level of timing noise unprecedented in a radio magnetar, though during the time covered by the radio data alone the timing noise was at a level similar to that observed in other radio magnetars. While SGR J1745–2900 is similar to other radio magnetars in many regards, it differs by having experienced a period of relative stability in the radio that now appears to have ended, while the X-ray properties evolved independently.

  17. Game development with Swift

    CERN Document Server

    Haney, Stephen

    2015-01-01

    If you wish to create and publish fun iOS games using Swift, then this book is for you. You should be familiar with basic programming concepts. However, no prior game development or Apple ecosystem experience is required.

  18. NuSTARand Swift observations of the very high state in GX 339-4: Weighing the black hole with X-rays

    DEFF Research Database (Denmark)

    Parker, M. L.; Tomsick, J. A.; Kennea, J. A.

    2016-01-01

    We present results from spectral fitting of the very high state of GX 339-4 with Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift. We use relativistic reflection modeling to measure the spin of the black hole and inclination of the inner disk and find a spin of a = 0.95(-0.08)(+0.02) and ......We present results from spectral fitting of the very high state of GX 339-4 with Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift. We use relativistic reflection modeling to measure the spin of the black hole and inclination of the inner disk and find a spin of a = 0...

  19. Mammographic follow-up after conservation therapy for breast cancer

    International Nuclear Information System (INIS)

    Gu Yajia; Xiao Qin; Zheng Xiaojing; Wu Jiong; Chen Jiayi; Gu Rongfeng; Feng Xiaoyuan

    2006-01-01

    Objective: To recognize the mammographic changes after conservation therapy for breast carcinoma. Methods: A total of 139 follow-up mammographic examinations in 85 cases were studied during the period between 1999 and 2004. Mammography was performed at intervals of 6 months for the first 2 years, then annually. Attention was paid to mammographic change patterns of conservation therapy for breast carcinoma, including breast edema, skin thickening, architectural disturbance, asymmetric density, architectural distortion retraction, and calcifications. SPSS version 11.0 for windows was used to perform all statistical tests. Kruskal-Wallis H test was used for calculating the overall statistical differences between difference periods. Categorical data were expressed as percentages and analyzed by using the X 2 test. The age of the patients ranged from 25 to 63 years (mediate, 44 years old). The time of follow-up observation ranged from 1 week to 72 months. Results: Two cases were normal on mammograms. High proportion of abnormal mammography was seen in the period of 12 month (40.3%, 56/139) and 24 month (21.6%, 30/139), respectively. Various findings appeared in various periods and the difference was statistically significant(X 2 =30.998, v=6, P=0.001). Mild edema appeared in the first 3 years. Moderately severe or marked breast edema may be present between 6 months to 12 months, then slowly resolved. The appearance and disappearance of skin thickening were similar to the process of breast edema. The changes of architectural disturbance did not correlate with time (X 2 =8.634, P>0.05), but on sequential mammograms for same patient, the extent of architectural disturbance relieved over time (17/19). Asymmetric density was found in only 5 patients, and disappeared in later period of follow-up in 3. Architectural distortion retraction got more and more obvious with time, and kept stable after certain period of time. Calcifications were shown in 2 patients, including 1

  20. [Follow-up of patients with inflammatory bowel disease].

    Science.gov (United States)

    García-López, Santiago

    2013-10-01

    Multiple data were presented on inflammatory bowel disease (IBD) in Digestive Disease Week (DDW). Of particular interest to gastroenterologists were those on novel treatments and information on safety. Other data, such as those relating to disease "follow-up", were possibly of lesser interest. However, the information reported this year was, in my opinion, highly important, because it could lead to significant changes in clinical practice. Thus, results presented strongly suggest that patients with asymptomatic IBD, specifically Crohn's disease (CD), often develop complications during their clinical course. Moreover, this is especially true in patients with CD and biological signs of inflammation, despite being asymptomatic. In addition, it seems clear that the absence of symptoms does not imply an absence of inflammation. These observations indicate a dual practical message: patients should be followed-up and objectively evaluated. Multiple data were presented on how to objectively evaluate disease activity in IBD. The prognostic value and objectivity of endoscopy has been reaffirmed, specifically with new data on the only validated index, the UCEIS, in ulcerative colitis. Together with endoscopy, the role of less invasive techniques such as imaging tests (magnetic resonance enterography, computed tomography enterography and even echography, with and without contrast agent) and fecal markers has been reaffirmed in several conditions and these techniques have a certain predictive value. Finally, many studies were reported that confirm the therapeutic activity of levels of anti-TNF and its antibodies in certain conditions and with some limitations. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  1. Carcinoembryonic Antigen (CEA) in colorectal cancer follow-up

    NARCIS (Netherlands)

    Verberne, Charlotte

    2016-01-01

    Colorectal cancer follow-up aims to detect recurrent disease as soon as possible, since earlier detection of recurrent disease is associated with greater chances for cure. A part of follow-up is the measurement of Carcinoembryonic Antigen (CEA) in the blood of the patient. This tumor marker is

  2. National screening program vs. standardized neurodevelopmental follow-up

    NARCIS (Netherlands)

    Maschke, Cornelia; Ellenrieder, Birte; Hecher, Kurt; Bartmann, Peter

    Background: Long-term follow-up is urgently needed to decide on the consequences of new therapies. Objective: This study assesses the use of a national child development screening program for a follow-up examination of a defined patient group. Patients and methods: Neurodevelopmental outcome of 139

  3. Incontinentia pigmenti: case report and 5-year follow-up

    Directory of Open Access Journals (Sweden)

    Ayşegül Sarı

    2017-09-01

    Full Text Available Introduction: Incontinentia Pigmenti (Bloch-Sulzberger Syndrome is a disease of organ involvement with ectodermic and mesodermic origin, showing dominant transition based on the X-chromosome. It affects the skin, eyes, teeth, and central nervous system. Case Report: The patient diagnosed with Incontinentia Pigmenti was referred from the Department of Dermatology, Faculty of Medicine, Mustafa Kemal University to the Department of Periodontology, Faculty of Dentistry, Mustafa Kemal University to consult whether there was anomaly in tooth germs and crests in the mouth. The patient was followed in our clinic for 5 years (examinations at 42 days, 6 months and 5 years. In the extraoral examinations, second-grade hyperkeratotic erythematous papules and plaques on the arms and legs, and linearly-arranged hyperpigmented and hypopigmented macular lesions at various grades were seen. In the intraoral examinations, no anomalies were observed in the crests and the palate during the toothless period. However, during the dentition period, wedge-shaped teeth and oligodontia were observed. In the 5-year follow-up period, no deficiency was observed in the patient's body and mental development compared with the peers. Conclusion: Early diagnosis of Incontinentia Pigmenti can be made through observation of the dental anomalies. There is no specific treatment of this disease. As it affects multiple systems of the human body, it requires monitoring and treatment with interdisciplinary approaches.

  4. New methods for estimating follow-up rates in cohort studies

    Directory of Open Access Journals (Sweden)

    Xiaonan Xue

    2017-12-01

    Full Text Available Abstract Background The follow-up rate, a standard index of the completeness of follow-up, is important for assessing the validity of a cohort study. A common method for estimating the follow-up rate, the “Percentage Method”, defined as the fraction of all enrollees who developed the event of interest or had complete follow-up, can severely underestimate the degree of follow-up. Alternatively, the median follow-up time does not indicate the completeness of follow-up, and the reverse Kaplan-Meier based method and Clark’s Completeness Index (CCI also have limitations. Methods We propose a new definition for the follow-up rate, the Person-Time Follow-up Rate (PTFR, which is the observed person-time divided by total person-time assuming no dropouts. The PTFR cannot be calculated directly since the event times for dropouts are not observed. Therefore, two estimation methods are proposed: a formal person-time method (FPT in which the expected total follow-up time is calculated using the event rate estimated from the observed data, and a simplified person-time method (SPT that avoids estimation of the event rate by assigning full follow-up time to all events. Simulations were conducted to measure the accuracy of each method, and each method was applied to a prostate cancer recurrence study dataset. Results Simulation results showed that the FPT has the highest accuracy overall. In most situations, the computationally simpler SPT and CCI methods are only slightly biased. When applied to a retrospective cohort study of cancer recurrence, the FPT, CCI and SPT showed substantially greater 5-year follow-up than the Percentage Method (92%, 92% and 93% vs 68%. Conclusions The Person-time methods correct a systematic error in the standard Percentage Method for calculating follow-up rates. The easy to use SPT and CCI methods can be used in tandem to obtain an accurate and tight interval for PTFR. However, the FPT is recommended when event rates and

  5. Bilateral sacrospinous fixation without hysterectomy: 18-month follow-up

    Science.gov (United States)

    Şentürk, Mehmet Baki; Güraslan, Hakan; Çakmak, Yusuf; Ekin, Murat

    2015-01-01

    Objective The aim of this study was to evaluate the results of bilateral sacrospinous fixation (SSF), which was performed with surgical mesh interposition and bilateral vaginal repair. Material and Methods Twenty-two patients underwent SSF between 2010 and 2012, and the results were evaluated retrospectively. The results at preoperative and postoperative 6th, 12th, and 18th months of the pelvic organ prolapse quantification system (POP-Q) and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12 (PISQ-12) were compared using Friedman and Wilcoxon Signed Ranks tests. Values of p<0.05 and <0.01 were considered statistically significant. Results According to the POP-Q, significant healing was observed on all vaginal vault points (p=0.001), and no prolapse was observed until the 18-month follow-up stage. There were also prominent patients who felt satisfactory with respect to their sexual life according to PISQ-12 (p=0.001). Conclusion This technique appears to provide an adequate clinical resolution, and it may be the primary surgical option for women with pelvic organ prolapse. PMID:26097393

  6. Low-Density Lipoprotein Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men With Primary Elevations of Low-Density Lipoprotein Cholesterol Levels of 190 mg/dL or Above: Analyses From the WOSCOPS (West of Scotland Coronary Prevention Study) 5-Year Randomized Trial and 20-Year Observational Follow-Up.

    Science.gov (United States)

    Vallejo-Vaz, Antonio J; Robertson, Michele; Catapano, Alberico L; Watts, Gerald F; Kastelein, John J; Packard, Chris J; Ford, Ian; Ray, Kausik K

    2017-11-14

    Patients with primary elevations of low-density lipoprotein cholesterol (LDL-C) ≥190 mg/dL are at a higher risk of atherosclerotic cardiovascular disease as a result of long-term exposure to markedly elevated LDL-C levels. Therefore, initiation of statin therapy is recommended for these individuals. However, there is a lack of randomized trial evidence supporting these recommendations in primary prevention. In the present analysis, we provide hitherto unpublished data on the cardiovascular effects of LDL-C lowering among a primary prevention population with LDL-C ≥190 mg/dL. We aimed to assess the benefits of LDL-C lowering on cardiovascular outcomes among individuals with primary elevations of LDL-C ≥190 mg/dL without preexisting vascular disease at baseline. We performed post hoc analyses from the WOSCOPS (West of Scotland Coronary Prevention Study) randomized, placebo-controlled trial, and observational posttrial long-term follow-up, after excluding individuals with evidence of vascular disease at baseline. WOSCOPS enrolled 6595 men aged 45 to 64 years, who were randomly assigned to pravastatin 40 mg/d or placebo. In the present analyses, 5529 participants without evidence of vascular disease were included, stratified by LDL-C levels into those with LDL-C coronary heart disease and major adverse cardiovascular events were assessed over the 4.9-year randomized controlled trial phase and on mortality outcomes over a total of 20 years of follow-up. Among 5529 individuals without vascular disease, pravastatin reduced the risk of coronary heart disease by 27% ( P =0.002) and major adverse cardiovascular events by 25% ( P =0.004) consistently among those with and without LDL-C ≥190 mg/dL ( P -interaction >0.9). Among individuals with LDL-C ≥190 mg/dL, pravastatin reduced the risk of coronary heart disease by 27% ( P =0.033) and major adverse cardiovascular events by 25% ( P =0.037) during the initial trial phase and the risk of coronary heart disease death

  7. Treatment, follow-up and microbiota in acute diverticulitis

    NARCIS (Netherlands)

    Daniels, L.

    2015-01-01

    Er bestaat veel controverse rondom diverticulitis. Er is tegenstrijdigheid omtrent de beste behandeling van de verschillende stadia. Voor acute ongecompliceerde diverticulitis is het onzeker of antibiotica nodig zijn. De waarde van routine follow-up colonoscopie wordt betwijfeld. Er bestaat

  8. Post-Discharge Follow-Up Visits and Hospital Utilization

    Data.gov (United States)

    U.S. Department of Health & Human Services — Analysis reported in Post-Discharge Follow-Up Visits and Hospital Utilization by Medicare Patients, 2007-2010, published in Volume 4, Issue 2 of Medicare and...

  9. Management of follow-up of neuroendocrine neoplasias.

    Science.gov (United States)

    Pape, Ulrich-Frank; Maasberg, Sebastian; Jann, Henning; Pschowski, René; Krüger, Sandrine; Prasad, Vikas; Denecke, Timm; Wiedenmann, Bertram; Pascher, Andreas

    2016-01-01

    Neuroendocrine neoplasias (NEN) comprise heterogeneous epithelial neoplasms with a large variety of clinical presentations, treatment options and outcomes. Since potentially all NEN bear malignant potential it is important for long-term clinical management and improvement of outcome to decide on successful and oncologically and economically meaningful follow-up strategies. Evidence-based outcome data validating specific follow-up strategies are, however, not available to date and thus outcome data, known prognostic factors and clinical experience guide the decisions on follow-up regimens. The review summarizes general recommendations as well as specific considerations based on tumor entities, clinicopathological tumor characteristics and clinical experience. Follow-up shall serve the patient to improve outcome, benefit from more effective therapies and suffer less from unnecessary and/or toxic therapeutic interventions and finally preserve or gain a good quality of life. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Pediatric Celiac Disease: Follow-Up in the Spotlight.

    Science.gov (United States)

    Valitutti, Francesco; Trovato, Chiara Maria; Montuori, Monica; Cucchiara, Salvatore

    2017-03-01

    The follow-up of celiac disease (CD) is challenging due to the scarcity of published data and the lack of standardized evidence-based protocols. The worldwide frequency and methods of CD follow-up appear to be heavily influenced by expert opinions of the individual physicians who assess children with CD. The aim of this review was to summarize the available studies on CD follow-up in children. We conducted a literature search with the use of PubMed, Medline, and Embase (from 1900 to 15 December 2016) for terms relevant to this review, including CD, follow-up, dietary adherence or dietary compliance, nutrition, comorbidities, complications, and quality of life. The aims of follow-up are as follows: to ensure strict adherence to a gluten-free diet, to ensure nutritional adequacy, to improve quality of life, and to prevent disease complications. For the correct evaluation of children with CD at follow-up, a clinical and biochemical evaluation is necessary on a regular basis. It is advisable to assess compliance, nutrition, comorbidities, or possible complications once a year at the referral center. Laboratory tests might be useful for a thorough evaluation of any patient with CD to rule out a micronutrient deficiency (full blood count, ferritin, folic acid, vitamin B-6, and vitamin B-12) and possible cardiovascular risk factors (glucose, LDL cholesterol, triglycerides). Biochemical evaluation is essential when there are clinical problems and should be customized on the basis of the specific clinical suspicion. Associated autoimmune thyroiditis should also be screened for yearly by measuring thyroid-stimulating hormone and thyroid autoantibody concentrations, regardless of symptoms, because hypothyroidism is often subtle and methods for early treatment are available and desirable. Although evidence-based recommendations for follow-up of pediatric patients with CD have not yet been established, we advise a yearly follow-up visit as the safest approach. © 2017 American

  11. Use of mobile phones to improve follow-up rates

    African Journals Online (AJOL)

    Dear editor: I read with interest your article titled, “Assessing the feasibility of mobile phones for follow-up of acutely unwell children presenting to village clinics in rural northern. Malawi,” by Hardy et al.1 It is indeed enlightening to know that concrete efforts are being made to ensure follow-up for acutely unwell kids below the ...

  12. Diagnosis, treatment and follow up of neonatal arrhythmias.

    Science.gov (United States)

    Binnetoğlu, Fatih Köksal; Babaoğlu, Kadir; Türker, Gülcan; Altun, Gürkan

    2014-01-01

    This study aimed to evaluate the aetiology, spectrum, course and outcomes of neonates with arrhythmias observed in a tertiary neonatal intensive care unit from 2007 to 2012. Neonates with rhythm problems were included. The results of electrocardiography (ECG), Holter ECG, echocardiography and biochemical analysis were evaluated. The long-term results of follow up were reviewed. Forty-five patients were male (68%) and 21 (32%) were female. Fifty-five patients (83.3%) were term, 11 (16.6%) were preterm, and 34% were diagnosed in the prenatal period. Twenty cases (30.3%) had congenital heart disease. Twenty-three patients (34.8%) were diagnosed during the foetal period. The most common arrhythmias were supraventricular ectopic beats and supraventricular tachycardia (SVT) at 39.3 and 22.7%, respectively. SVT recurred in five patients after the neonatal period. Supraventricular ectopic beats and SVT were the most common arrhythmias during the neonatal period. Although the prognosis of arrhythmias in the neonatal period is relatively good, regular monitoring is required.

  13. WFIRST Microlensing Exoplanet Characterization with HST Follow up

    Science.gov (United States)

    Bhattacharya, Aparna; David Bennett, Jay Anderson, J.P. Beaulieu.

    2018-01-01

    More than 50 planets are discovered with the different ground based telescopes available for microlensing. But the analysis of ground based data fails to provide a complete solution. To fulfill that gap, space based telescopes, like Hubble space telescope and Spitzer are used. My research work focuses on extracting the planet mass, host star mass, their separation and their distance in physical units from HST Follow-up observations. I will present the challenges faced in developing this method.This is the primary method to be used for NASA's top priority project (according to 2010 decadal survey) Wide Field InfraRed Survey Telescope (WFIRST) Exoplanet microlensing space observatory, to be launched in 2025. The unique ability of microlensing is that with WFIRST it can detect sub-earth- mass planets beyond the reach of Kepler at separation 1 AU to infinity. This will provide us the necessary statistics to study the formation and evolution of planetary systems. This will also provide us with necessary initial conditions to model the formation of planets and the habitable zones around M dwarf stars.

  14. The Swift Turbidity Marker

    Science.gov (United States)

    Omar, Ahmad Fairuz; MatJafri, Mohd Zubir

    2011-01-01

    The Swift Turbidity Marker is an optical instrument developed to measure the level of water turbidity. The components and configuration selected for the system are based on common turbidity meter design concepts but use a simplified methodology to produce rapid turbidity measurements. This work is aimed at high school physics students and is the…

  15. Follow up of Graves' Opthalmopathy after radioiodine therapy

    International Nuclear Information System (INIS)

    Miah, M.S.R.; Paul, A. K.; Rahman, H.A.

    2002-01-01

    Graves' ophthalmopathy may first appear or worsen during or after treatment for hyperthyroidism. We followed up 158 Graves' hyperthyroid patients treated with radioiodine of which 49 had Grave's' ophthalmopathy during presentation in Nuclear Medicine Centre, Khulna during the period from 1995 to 2000. The aim of our study is to see the effect of radioiodine in Graves' ophthalmopathy. All the patients received radioiodine at fixed dose regime ranged from 7 mCi to 12 mCi. The duration of follow up was at least 12 months Graves' ophthalmopathy patients, 4 (4/49 i.e., 8.2%) showed exaggeration of ophthalmopathy and the rest (45/49 i.e., 91.8%) remained unchanged. None of ophthalmopathy developed among any of Graves' hyperthyroid or disappeared after radioiodine treatment during follow up period. From the study we concluded that eye changes in Graves' hyperthyroidism remain unchanged or exaggerated after radioiodine therapy and needs ophthalmologist care.(author)

  16. Course of disease and follow-up in breast cancer

    International Nuclear Information System (INIS)

    Ebner, F.; Hackl, H.; Hoermann, M.; Schneider, G.

    1986-01-01

    Besides individual care, regular follow-up studies in breast cancer patients have different aims, relative to different tumor stages at presentation. In early stages emphasis has to be laid on detection of loco-regional recurrences, which will not reduce overall survival if diagnosed and treated early. In addition, treatment effects and changes in the activity of disease are evaluated. Radiographic studies for detection of distant metastases are justified if followed by proper treatment. Early diagnosis of cancer of the opposite breast and of such cancers that are associated with breast cancer (colon, ovaries, endometrium) is imperative. The aim of a regular follow-up in more advanced tumor stages is to monitor the extent of disease and to prevent complications (e.g. fractures, spinal cord compression). In familial breast cancer first degree relatives should be included in the follow-up plan. The patient's psychosocial needs, even if not verbalized, should not be neglected. (Author)

  17. [Post-ART follow-up for women].

    Science.gov (United States)

    Epelboin, S

    2008-08-01

    The follow-up of women after ART is for the most part related, over the short and long term, to the follow-up of the child born through ART. What is important to know is the possible repercussions of treatment on women's health over the short and long term. To date, no study has proven that menopause comes on earlier after ART treatments. Similarly, none of the international studies has demonstrated a significant increase in breast, ovary, uterus, or colon cancer related to ovulation-inducing treatment. However, for reasons of safety, vigilance is required. Large-scale follow-up of this nature essentially involves crossing registries (cancers, ART), but must respect the desires of women not to be indefinitely reminded of their past infertility. In addition, a study is reported on pursuing the parental project in a cohort of 1200 women who delivered at least one child conceived through MAP more than 3 years before.

  18. Acromegalic patients lost to follow-up: a pilot study.

    Science.gov (United States)

    Kasuki, Leandro; Marques, Nelma Verônica; Nuez, Maria José Braga La; Leal, Vera Lucia Gomes; Chinen, Renata N; Gadelha, Mônica R

    2013-06-01

    Approximately 50 % of all acromegalic patients will require lifelong medical treatment to normalize mortality rates and reduce morbidity. Thus, adherence to therapy is essential to achieve treatment goals. To date, no study has evaluated the frequency and reasons for loss to follow-up in the acromegalic population. The current study aimed at evaluating the frequency of acromegalic patient loss to follow-up in three reference centers and the reasons responsible for their low compliance with treatment. All of the files for the acromegalic patients in the three centers were reviewed. Those patients, who had not followed up with the hospital for more than a year, were contacted via phone and/or mail and invited to participate. Patients who agreed to participate were interviewed, and blood samples were collected. A total of 239 files were reviewed; from these 42 patients (17.6 %) were identified who were lost to follow-up. It was possible to contact 27 of these patients, 10 of whom did not attend the appointments for more than one time and 17 of whom agreed to participate in the study. Fifteen of these 17 patients had active disease (88.2 %), and all of the patients restarted treatment in the original centers. The main reason for loss to follow-up was an absence of symptoms. High-quality follow-up is important in acromegaly to successfully achieve the aims of the treatment. An active search for patients may allow the resumption of treatment in a significant proportion of these cases, contributing to reduced morbidity and mortality in this patient population.

  19. Exercise-Induced Ventricular Fibrillation: Seven Years Follow-Up

    Directory of Open Access Journals (Sweden)

    Gökmen Gemici

    2011-11-01

    Full Text Available We present a 7-year follow-up of a 55-year-old male who experienced ventricular fibrillation during the recovery period of exercise testing and refused implantation of an ICD. Normal left ventricular systolic function was found on echocardiographic examination, and coronary angiography revealed only a side branch disease with a vessel diameter of less than 2 millimeters. The patient was discharged on metoprolol and ASA in addition to his previous treatment with lisinopril and simvastatin. Outpatient cardiac evaluation by repeated 24-hour ECG monitorizations (Holter revealed normal findings. On follow up visits every six months for the past seven years, the patient was found to be asymptomatic.

  20. Danish offshore wind. Key environmental issues - a follow-up

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-02-15

    This follow-up to the Danish environmental monitoring programme on large-scale offshore wind power builds on the result of the former programme of 2006 and focuses on updated knowledge on harbour porpoises, water birds and fish communities, and on the cumulative effects of wind farms. The scientific quality of the projects in this follow-up has been assessed by experts from the International Advisory Panel of Experts on Marine Ecology (IAPEME), who have commented on the results in an independent evaluation which is reproduced in this publication. (LN)

  1. Group anxiety management: effectiveness, perceived helpfulness and follow-up.

    Science.gov (United States)

    Cadbury, S; Childs-Clark, A; Sandhu, S

    1990-05-01

    An evaluation was conducted on out-patient cognitive-behavioural anxiety management groups. Twenty-nine clients assessed before and after the group and at three-month follow-up showed significant improvement on self-report measures. A further follow-up on 21 clients, conducted by an independent assessor at an average of 11 months, showed greater improvement with time. Clients also rated how helpful they had found non-specific therapeutic factors, and specific anxiety management techniques. 'Universality' was the most helpful non-specific factor, and 'the explanation of anxiety' was the most helpful technique.

  2. Clinical 3-year follow-up of uterine fibroid embolization

    International Nuclear Information System (INIS)

    Radeleff, B.A.; Satzl, S.; Eiers, M.; Fechtner, K.; Hakim, A.; Kauffmann, G.W.; Richter, G.M.; Rimbach, S.

    2007-01-01

    Purpose: The purpose of this study was to evaluate the clinical long-term success of uterine artery embolization (UAE) in patients with symptomatic fibroids using spherical particles (Embosphere). Materials and Methods: 34 consecutive patients treated with UAE were initially enrolled in the study which had the following study goals (1) 1-year follow-up MRI evaluation of the fibroid behavior and (2) clinical long-term success due to standardized assessment of the main fibroid-related symptoms (hypermenorrhoea, dysmenorrhoea and dysuria) of the patients' individual overall health status and their therapy satisfaction at 1-year, 2- year and 3-year intervals after UAE. Results: Technical success was achieved in all procedures. Four patients had to be excluded from the long-term evaluation schedule: one because of a hysterectomy due to bleeding after 6 weeks, 3 patients were not available for the designated minimum follow-up interval. The preinterventional severe hypermenorrhoea (n = 27) with a score of 4.4 ± 0.7 (5 = extreme menstrual bleeding) decreased after one year to 2.1 ± 0.5 (p = 0.0001), after two years to 1.7 ± 0.5 (p = 0.0042) and after three years to 1.3 ± 0.6 (p = 0.0001). The preinterventional dysmenorrhoea (n = 15) with a score of 3.1 ± 1.5 (3 = distinctly increased dysmenorrhoea) decreased after one year to 1.1 ± 0.3 (p = 0.0001), after two years to 1.2 ± 0.2 and after three years to 1.2 ± 0.4 (p = 0.148). The pretreatment dysuria (n = 12) with a preinterventional score of 3.1 ± 1.5 (3 = distinctly increased dysuria) decreased after one year to 1.1 ± 0.3 (p 0.0069) and remained after two years at 1.1 ± 0.2 and after three years at 1.2 ± 0.4 (p = 0.905). The initial overall health status was 54.7 ± 20.1 (maximal value 100). After one year it rose to 90.5 ± 15.4 (p = 0.0001), was 91.8 ± 5.6 after two years and was 91.3 ± 8.5 (p = 0.8578) after three years. The satisfaction with the therapy was 2.9 ± 0.2 after one year, 2.6 ± 0.3 after two

  3. Lord of the Rings – Return of the King: Swift-XRT observations of dust scattering rings around V404 Cygni

    OpenAIRE

    Beardmore, A.P.; Willingale, R.; Kuulkers, E.; Altamirano, D.; Motta, S.E.; Osborne, J.P.; Page, K.L.; Sivakoff, G.R.

    2016-01-01

    On 2015 June 15, the black hole X-ray binary V404 Cygni went into outburst, exhibiting extreme X-ray variability which culminated in a final flare on June 26. Over the following days, the Swift-X-ray Telescope detected a series of bright rings, comprising five main components that expanded and faded with time, caused by X-rays scattered from the otherwise unobservable dust layers in the interstellar medium in the direction of the source. Simple geometrical modelling of the rings’ angular evol...

  4. Challenges of loss to follow-up in tuberculosis research

    DEFF Research Database (Denmark)

    Nissen, Thomas N; Rose, Michala V; Kimaro, Godfather

    2012-01-01

    In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results. In a study assessing the diagnostic performance of the QuantiFERON®-TB Gold In-Tube test...

  5. the optimum radiographic follow-up of a giant vertebrobasiler ...

    African Journals Online (AJOL)

    BEYINCERRSEM

    Key Words: Endovascular coil embolization, long term follow up, vertebro basilar junction aneurysm. ... angiography, a giant vertebrobasilar junction saccular .... Seruga T, Klein GE .Endovascular treatment of intracranial artery aneurysms in the posterior cerebral circulation. Wien Klin Wochenschr. 2004;116 Suppl 2:13-8. 2.

  6. Loss to Follow-Up: Issues and Recommendations

    Science.gov (United States)

    Hoffman, Jeff; Munoz, Karen F.; Bradham, Tamala S.; Nelson, Lauri

    2011-01-01

    State coordinators of early hearing detection and intervention (EHDI) programs completed a strengths, weaknesses, opportunities, and threats, or SWOT, analysis that examined 12 areas within state EHDI programs. Related to how EHDI programs address loss to follow-up, 47 coordinators responded with 277 items, and themes were identified in each…

  7. [Follow-up and treatment outcome of early anorexia nervosa].

    Science.gov (United States)

    Schulze, U; Neudörfl, A; Krill, A; Warnke, A; Remschmidt, H; Herpertz-Dahlmann, B

    1997-03-01

    In a two-center follow-up study on the early-onset form of anorexia nervosa, we reexamined 43 (74%) of 58 former patients who had developed anorexia nervosa at the age of 13 years or younger. In addition to make a standardized assessment of the eating disorder at follow-up we assessed psychiatric comorbidity with a structured interview based on the criteria of DSM-III-R and ICD-10. After an average follow-up period of 6.8 years, 8 (18%) of our former patients had an eating disorder not otherwise specified (EDNOS) and 4 (9%) still suffered from anorexia nervosa. 5 (11%) of the subjects had developed bulimia nervosa. In 3 cases (7%) we found both syndromes. 12 (28%) of our former patients had an additional psychiatric disorder. The results of our study indicate that the quality of outcome in patients with an early-onset form of anorexia nervosa does not differ from that in individuals with a later manifestation of the eating disorder. Factors of prognostic relevance were the existence of an eating disorder during the first year of life and the duration of the follow-up period.

  8. Immediate Follow-Up in Orientation Program Evaluation

    Science.gov (United States)

    Smith, Thomas T.; Hurst, James C.

    1974-01-01

    The purpose of this study is to investigate whether differing time intervals between the conclusion of the Summer Orienation Program at Colorado State University and the follow-up assessment of the program yield different results. Such differentiation was not found. (Author/RP)

  9. A formula for continued improvement: Audit follow-up

    International Nuclear Information System (INIS)

    Maday, J.H. Jr.

    1989-10-01

    In his book Management Audits, Allan J. Sayle states, ''QA standards stipulate that corrective action, required as a result of performing an audit, be followed up and closed out. There would, indeed, be little point in performing audits, requiring corrective action, or having a QA system at all if the auditee knows that the auditor will never verify that the corrective action has been efficaciously implemented.'' The QA auditor has an obligation to include follow-up in the overall audit planning. All too often the auditor will go to great lengths to plan and perform an audit only to have a recurring finding in the next audit. The proposed corrective action was only promissory and was not designed to stop the problem from recurring or to identify its root cause. Auditors do a disservice to the overall QA program and particularly to the customer when they fail to follow up and verify that an audit corrective action has been effectively implemented. In this paper, the techniques used by the quality assurance auditors at the Pacific Northwest Laboratory (PNL) will be presented. Although PNL is a research and development laboratory, the techniques outlined in this paper could be applied to any industry conducting quality assurance audits. Most important, they provide a formula for continued improvement by assuring that audit follow-up is timely, meaningful, and permanent

  10. The Danish Cerebral Palsy follow-up Program

    DEFF Research Database (Denmark)

    Rasmussen, Helle Mätzke; Nordbye-Nielsen, Kirsten; Møller-Madsen, Bjarne

    2016-01-01

    -15 years and children with symptoms of CP aged 0-5 years. MAIN VARIABLES: In the follow-up program, the children are offered examinations throughout their childhood by orthopedic surgeons, physiotherapists, occupational therapists, and pediatricians. Examinations of gross and fine motor function, manual...

  11. Eight to ten years follow-up after carotid endarterectomy

    DEFF Research Database (Denmark)

    Knudsen Rathenborg, Lisbet; Sillesen, H; Schroeder, T

    1990-01-01

    Follow-up information was obtained on 185 patients who consecutively underwent carotid endarterectomy eight to ten years previously. Doppler ultrasound examination was performed in 59 patients who were still alive and living within 100 miles of the hospital. Using lifetable analysis, the annual r...

  12. Women's experiences of a follow up childbearing journey with ...

    African Journals Online (AJOL)

    The purpose of this study was to describe and analyse the lived experiences of the follow up journey of a pregnant woman by listening to the voices of women as they reflect on their journey. A qualitative, descriptive and contextual design was used to examine into each woman's experience of her world from pregnancy to ...

  13. Advances in diagnosis and follow-up in kidney cancer

    NARCIS (Netherlands)

    Rioja, Jorge; de La Rosette, Jean J. M. C. H.; Wijkstra, Hessel; Laguna, M. Pilar

    2008-01-01

    PURPOSE OF REVIEW: To review the most recent data on preoperative diagnostic methods in kidney cancer and in follow-up and monitoring after ablation therapy. RECENT FINDINGS: Although the role of the percutaneous biopsy in the diagnostics of renal masses has been limited, new data suggest a high

  14. MRI of penile fracture: diagnosis and therapeutic follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Uder, Michael; Gohl, Dietrich; Takahashi, Masahide; Kramann, Bernhard; Schneider, Guenther [Universitaet des Saarlandes, Homburg/Saar (Germany). Radiologische Klinik; Derouet, Harry [Universitaet des Saarlandes, Homburg/Saar (Germany). Urologische Klinik; Defreyne, Luc [Department of Radiology and Medical Imaging, University Hospital of Gent (Belgium)

    2002-01-01

    A rupture of corpus cavernosum (CC) is a rare injury of the erect penis. The present study describes the role of MRI for diagnosis and follow-up of this injury. Four patients with clinically suspected acute penile fractures underwent MRI. Imaging findings were confirmed at surgery. In three patients, follow-up MRI was also available at 1, 6 and 16 weeks after surgical repair. In all patients pre-contrast T1-weighted images (T1WI) clearly disclosed ruptures of CC, which depicted as discontinuity of low signal intensity of the tunica albuginea (TA). Concomitant subcutaneous haematoma were well visualised both on T1-weighted (T1WI) and T2-weighted images, whereas haematoma in CC were optimally demonstrated on contrast-enhanced T1WI. On follow-up MRI all fractures presented similar healing process. Shortly after the repair, the tunical suture showed an increase in signal intensity on pre-contrast T1WI and was strongly enhanced with the administration of contrast material. Then the tear site gradually recovered low signal intensity on all spin-echo sequences by 4 months after surgery. These serial findings may suggest the formation of vascularised granulation tissue during cicatrisation. Magnetic resonance imaging is of great value for the diagnosis and follow-up in patients with penile fracture. (orig.)

  15. Long-Term Follow Up of Superficial Bladder Tumors | Shelbaia ...

    African Journals Online (AJOL)

    Conclusion: The treatment of superficial TCC may be done by relatively minor endoscopic procedures, but the disease itself is a serious condition that merits close long-term follow-up. Key words: bladder tumors, transitional cell carcinoma (TCC), ND: YAG lasers, transurethral resection (TURT) Suivi à long terme des ...

  16. 38 CFR 41.315 - Audit findings follow-up.

    Science.gov (United States)

    2010-07-01

    ... include audit findings from multiple years, it shall include the fiscal year in which the finding... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Audit findings follow-up... (CONTINUED) AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 41.315 Audit...

  17. 7 CFR 3052.315 - Audit findings follow-up.

    Science.gov (United States)

    2010-01-01

    ... schedule may include audit findings from multiple years, it shall include the fiscal year in which the... 7 Agriculture 15 2010-01-01 2010-01-01 false Audit findings follow-up. 3052.315 Section 3052.315..., DEPARTMENT OF AGRICULTURE AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 3052...

  18. 29 CFR 99.315 - Audit findings follow-up.

    Science.gov (United States)

    2010-07-01

    ... schedule may include audit findings from multiple years, it shall include the fiscal year in which the... 29 Labor 1 2010-07-01 2010-07-01 true Audit findings follow-up. 99.315 Section 99.315 Labor Office of the Secretary of Labor AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees...

  19. Developmental screening: predictors of follow-up adherence in ...

    African Journals Online (AJOL)

    Abstract. Background: The importance of early identification for infants and young children with developmental delays is well estab- lished. Poor follow-up on referrals, however, undermines the effectiveness of early intervention programmes. Objectives: To identify factors, including text message reminders, that influence ...

  20. Solitary Functioning Kidney in Children - A Follow-Up Study

    Directory of Open Access Journals (Sweden)

    Gabriel Kolvek

    2014-08-01

    Full Text Available Background/Aims: This study aims to assess the cumulative incidence of elevated albuminuria, hypertension and decreased estimated glomerular filtration rate (eGFR to identify possible renal injury in children with SFK. Methods: Forty-two children with SFK (23 boys; 27 congenital were included in a prospective follow-up study. Blood pressure, albuminuria and eGFR were assessed repeatedly and the cumulative incidence rate of various forms of renal injury, overall and by type of etiology, were evaluated. Finally, renal injury-free survival was analyzed. Results: Mean follow-up was until age 11.3 years (SD 6.3 years. During follow-up, 16 (38.1% patients met the criteria for renal injury, defined as hypertension (10; 23.8%, severely increased albuminuria (3; 7.1% and a significantly impaired eGFR (2 (5; 11.9% and/or use of antihypertensive or antiproteinuric medication (11; 26.2%. Children with CAKUT in SFK had a significantly higher incidence of renal injury. The median time to develop renal injury was 12.8 years. Conclusion: A substantial proportion of children with SFK develop renal injury during childhood, especially those with CAKUT in the SFK. Therefore, close follow-up of albuminuria, blood pressure and eGFR are warranted to identify chronic kidney disease in its early stages.

  1. Immunological follow-up of hydatid cyst cases

    Directory of Open Access Journals (Sweden)

    Bulut Vedat

    2001-01-01

    Full Text Available Hydatid disease is caused by Echinococcus granulosus. In this study, we aimed to investigate the benefit of monitoring cases with hydatid cyst by means of immune components in patients in a long-term follow-up after surgery. Eighty-four preoperative and postoperative serum samples from 14 cases undergoing surgery for hydatid disease were evaluated in terms of immune parameters, such as total and specific IgE, IgG, IgM, IgA and complement. Total and specific IgE were determined by ELISA. Specific IgG levels were measured by indirect hemaglutination.Total IgG, IgM, IgA and complement (C3 and C4 were detected by nephelometry. Imaging studies were also carried out during the follow-up. In none of the patients hydatid cysts were detected during the follow-up. Total IgE levels in the sera of the patients decreased to normal six months after surgery. Although specific IgE against echinococcal antigens decreased one year after operation, levels were still significantly high. There were no changes in the levels of anti-Echinococcus IgG and total IgG in follow-up period. Additionally, other parameters, such as IgA, IgM, C3 and C4, were not affected.

  2. A Follow-Up Study of the Deaf.

    Science.gov (United States)

    Reich, P. A.; Reich, C. M.

    Followed up through interviews and questionnaires were 278 former students, average age 28 years, of two residential schools and one day school for the deaf in Ontario. Data was collected on the degree of hearing loss, use of a hearing aid, educational and occupational history, social integration, methods of communication, and attitudes toward…

  3. A Follow-Up Study of Former Student Health Advocates

    Science.gov (United States)

    Streng, Nancy J.

    2007-01-01

    Student health advocates (SHAs) are high school students who, under the supervision of the school nurse, provide health education and health promotion activities to other students via a peer education model. This 3-year follow-up study explored how the SHA experience influences career choice and attitudes of the participants. It also examined what…

  4. Student Perceptions of Educator Effectiveness: A Follow-Up Study

    Science.gov (United States)

    Sprinkle, Julie E.

    2009-01-01

    The current study investigates graduate student perceptions of educator effectiveness. This study is the follow-up to a pilot and instrument validation study conducted by the researcher. The findings of the previous study indicated student biases in areas such as gender, age, teaching style, learning style, grade awarded, and educator personality…

  5. Nimh Treatment Study of ADHD Follow-Up

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2004-04-01

    Full Text Available The effects of changes in medication use between 14 and 24 months follow-up on effectiveness (symptom ratings and growth (height and weight measures were analyzed, comparing 4 groups of patients, in the Multimodal Treatment Study of ADHD (MTA reported by the MTA Cooperative Group.

  6. Applicability of structured telephone monitoring to follow up heart ...

    African Journals Online (AJOL)

    Background: Studies from developed countries have shown that home monitoring and follow up of heart failure (HF) patients by use of phone calls is cost-effective as it reduces re-admission and improves patients' clinical status. This intervention has however not been tested in resource poor countries including Tanzania, ...

  7. Long-term follow-up of obstetric studies

    NARCIS (Netherlands)

    Teune, M.J.

    2013-01-01

    This thesis focuses on long-term child follow-up after obstetric studies. Obstetric randomized controlled clinical trials (RCTs) are performed to evaluate the effectiveness of perinatal interventions. However, most often only short-term outcomes are reported, while long-term outcomes are just as

  8. MFP-REA Follow-Up 2002-2005

    Science.gov (United States)

    2007-03-01

    ontwikkeld en volgt. Verwacbt kan worden dat dergellike 4/26 MVFIP-REA follow-up 2002-2005 systemnen binnen tien jaar op de markt verschijnen, waarmee de...prof. dr. P. Werkhoven 1 ex. TNO Defensie en Veiligheid, Directie Directeur Markt , G.D. Klein Baltink 1 ex. TNO Defensie en Veiligheid, vestiging Den

  9. Unruptured intracranial aneurysms: initial and follow-up screening

    NARCIS (Netherlands)

    Bor, A.S.E.

    2014-01-01

    Unruptured intracranial aneurysms may rupture, causing subarachnoid haemorrhage (SAH). SAH is a devastating subtype of stroke, resulting in death or severe disability in half the patients. This thesis has a focus on initial and follow-up screening for unruptured intracranial aneurysms, and consists

  10. Analytical framework and tool kit for SEA follow-up

    International Nuclear Information System (INIS)

    Nilsson, Mans; Wiklund, Hans; Finnveden, Goeran; Jonsson, Daniel K.; Lundberg, Kristina; Tyskeng, Sara; Wallgren, Oskar

    2009-01-01

    Most Strategic Environmental Assessment (SEA) research and applications have so far neglected the ex post stages of the process, also called SEA follow-up. Tool kits and methodological frameworks for engaging effectively with SEA follow-up have been conspicuously missing. In particular, little has so far been learned from the much more mature evaluation literature although many aspects are similar. This paper provides an analytical framework and tool kit for SEA follow-up. It is based on insights and tools developed within programme evaluation and environmental systems analysis. It is also grounded in empirical studies into real planning and programming practices at the regional level, but should have relevance for SEA processes at all levels. The purpose of the framework is to promote a learning-oriented and integrated use of SEA follow-up in strategic decision making. It helps to identify appropriate tools and their use in the process, and to systematise the use of available data and knowledge across the planning organization and process. It distinguishes three stages in follow-up: scoping, analysis and learning, identifies the key functions and demonstrates the informational linkages to the strategic decision-making process. The associated tool kit includes specific analytical and deliberative tools. Many of these are applicable also ex ante, but are then used in a predictive mode rather than on the basis of real data. The analytical element of the framework is organized on the basis of programme theory and 'DPSIR' tools. The paper discusses three issues in the application of the framework: understanding the integration of organizations and knowledge; understanding planners' questions and analytical requirements; and understanding interests, incentives and reluctance to evaluate

  11. Development of dual-beam system using an electrostatic accelerator for in-situ observation of swift heavy ion irradiation effects on materials

    Science.gov (United States)

    Matsuda, M.; Asozu, T.; Sataka, M.; Iwase, A.

    2013-11-01

    We have developed the dual beam system which accelerates two kinds of ion beams simultaneously especially for real-time ion beam analysis. We have also developed the alternating beam system which can efficiently change beam species in a short time in order to realize efficient ion beam analysis in a limited beam time. The acceleration of the dual beam is performed by the 20 UR Pelletron™ tandem accelerator in which an ECR ion source is mounted at the high voltage terminal [1,2]. The multi-charged ions of two or more elements can be simultaneously generated from the ECR ion source, so dual-beam irradiation is achieved by accelerating ions with the same charge to mass ratio (for example, 132Xe11+ and 12C+). It enables us to make a real-time beam analysis such as Rutherford Back Scattering (RBS) method, while a target is irradiated with swift heavy ions. For the quick change of the accelerating ion beam, the program of automatic setting of the optical parameter of the accelerator has been developed. The switchover time for changing the ion beam is about 5 min. These developments have been applied to the study on the ion beam mixing caused by high-density electronic excitation induced by swift heavy ions.

  12. Development of dual-beam system using an electrostatic accelerator for in-situ observation of swift heavy ion irradiation effects on materials

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, M., E-mail: matsuda.makoto@jaea.go.jp [Japan Atomic Energy Agency (JAEA-Tokai), Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan); Asozu, T.; Sataka, M. [Japan Atomic Energy Agency (JAEA-Tokai), Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan); Iwase, A. [Department of Materials Science, Osaka Prefecture University, 1-1 Gakuen-cho, Sakai, Osaka 599-8531 (Japan)

    2013-11-01

    We have developed the dual beam system which accelerates two kinds of ion beams simultaneously especially for real-time ion beam analysis. We have also developed the alternating beam system which can efficiently change beam species in a short time in order to realize efficient ion beam analysis in a limited beam time. The acceleration of the dual beam is performed by the 20 UR Pelletron™ tandem accelerator in which an ECR ion source is mounted at the high voltage terminal [1,2]. The multi-charged ions of two or more elements can be simultaneously generated from the ECR ion source, so dual-beam irradiation is achieved by accelerating ions with the same charge to mass ratio (for example, {sup 132}Xe{sup 11+} and {sup 12}C{sup +}). It enables us to make a real-time beam analysis such as Rutherford Back Scattering (RBS) method, while a target is irradiated with swift heavy ions. For the quick change of the accelerating ion beam, the program of automatic setting of the optical parameter of the accelerator has been developed. The switchover time for changing the ion beam is about 5 min. These developments have been applied to the study on the ion beam mixing caused by high-density electronic excitation induced by swift heavy ions.

  13. Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up.

    Science.gov (United States)

    Fici, F; Seravalle, G; Koylan, N; Nalbantgil, I; Cagla, N; Korkut, Y; Quarti-Trevano, F; Makel, W; Grassi, G

    2017-09-01

    Although improved during the past few years, blood pressure control remains sub optimal. The impact of follow-up assessment on blood pressure control was evaluated in a group of patients of the HYT (HYperTension survey), treated with a combination of different dihydropyridine calcium-channel blockers (CCBs regimen) and inhibitors of renin-angiotensin-aldosterone system (RAAS) and with uncontrolled blood pressure. This was obtained assessing (a) the rate of blood pressure control at 3 and 6 months of follow-up in the whole group of patients, (b) the rate of blood pressure control and the average blood pressure values in subjects treated with different DHP-CCBs regimen. From the 4993 patients with uncontrolled blood pressure, (BP ≥ 140/90 or ≥140/85 in patients with diabetes), 3729 (mean age 61.2 ± 11.5 years), maintained CCBs regimen combined wih RAAS blockers and were evaluated at 3 and 6 months follow-up. At each visit BP (semiautomatic device, Omron-M6, 3 measurements), heart rate, adverse events and treatment persistence were collected. At 1st and 2nd follow-up the rate of controlled BP was 63.5 and 72.8% respectively (p blood pressure control; (b) there is no significant difference in the antihypertensive effect between different CCBs regimen; (c) lipophilic CCBs induce less ankle edema.

  14. Curiosity and Exploratory Behavior in Disadvantaged Children: A Follow-Up Study.

    Science.gov (United States)

    Minuchin, Patricia P.

    In a follow-up study of curiosity and exploratory behavior, subjects were 18 disadvantaged inner-city black children who had been observed at age four in their first year of a Head Start program, and who were now finishing first grade. Data were obtained from teachers, observations in the classrooms, and an individual session with each child. Each…

  15. A Comparison of the Variability of the Symbiotic X-ray Binaries GX 1+4, 4U 1954+31, and 4U 1700+24 from Swift/BAT and RXTE/ASM Observations

    Science.gov (United States)

    Corbet, R. H. D.; Sokoloski, J. L.; Mukai, K.; Markwardt, C. B.; Tueller, J.

    2007-01-01

    We present an analysis of the X-ray variability of three symbiotic X-ray binaries, GX 1+4, 4U 1700+24, and 4U 1954+31, using observations made with the Swift Burst Alert Telescope (BAT) and the Rossi X-ray Timing Explorer (RXTE) All-Sky Monitor (ASM). Observations of 4U 1954+31 with the Swift BAT show modulation at a period near 5 hours. Models to explain this modulation are discussed including the presence of an exceptionally slow X-ray pulsar in the system and accretion instabilities. We conclude that the most likely interpretation is that 4U 1954+31 contains one of the slowest known X-ray pulsars. Unlike 4U 1954+31, neither GX 1+4 nor 4U 1700+24 show any evidence for modulation on a timescale of hours. An analysis of the RXTE ASM light curves of GX l+4, 4U 1700+24, and 4U 1954+31 does not show the presence of periodic modulation in any source, although there is considerable variability on long timescales for all three sources. There is no modulation in GX 1+4 on either the optical 1161 day orbital period or a previously reported 304 day X-ray period. For 4U 1700+24 we do not confirm the 404 day period previously proposed for this source from a shorter duration ASM light curve.

  16. [Normocalcemic primary hyperparathyroidism: recommendations for management and follow-up].

    Science.gov (United States)

    Martínez Díaz-Guerra, Guillermo; Jódar Gimeno, Esteban; Reyes García, Rebeca; Gómez Sáez, José Manuel; Muñoz-Torres, Manuel

    2013-10-01

    To provide practical recommendations for evaluation and follow-up of patients with normocalcemic primary hyperparathyroidism. Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology. A systematic search was made in MEDLINE (PubMed), using the terms normocalcemic primary hyperparathyroidism and primary hyperparathyroidism, for articles in English published before 22 November 2012. Literature was reviewed by 2 members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology, and after development of recommendations, the manuscript was reviewed by all other members of the Group, and their suggestions were incorporated. The document provides practical recommendations for evaluation and follow-up of patients with normocalcemic primary hyperparathyroidism. There is however little evidence available about different aspects of this disease, mainly progression rate and clinical impact. More data are therefore needed before definite recommendations may be made. Copyright © 2012 SEEN. Published by Elsevier Espana. All rights reserved.

  17. Nut consumption and incidence of metabolic syndrome after 6-year follow-up: the SUN (Seguimiento Universidad de Navarra, University of Navarra Follow-up) cohort.

    Science.gov (United States)

    Fernández-Montero, Alejandro; Bes-Rastrollo, Maira; Beunza, Juan J; Barrio-Lopez, Maria Teresa; de la Fuente-Arrillaga, Carmen; Moreno-Galarraga, Laura; Martínez-González, Miguel Angel

    2013-11-01

    To assess the long-term relationship between tree nut consumption and the risk of developing metabolic syndrome (MetS). Nut consumption was collected using a validated 136-item FFQ. The MetS was defined according to the International Diabetes Federation and American Heart Association/National Heart, Lung, and Blood Institute harmonizing definition. The association between nut consumption and MetS was assessed with logistic regression models adjusting for potential confounders. We compared the incidence of MetS between extreme categories of nut intake (> or = 2 servings/week v. never/almost never) after 6 years of follow-up. The SUN Project (Seguimiento Universidad de Navarra, University of Navarra Follow-up) is a prospective cohort study, formed of Spanish university graduates. Information is gathered by mailed questionnaires collected biennially. Nut consumption and MetS information was collected by self-reported data. Participants (n 9887) initially free of MetS or diabetes and followed up for a minimum of 6 years were included. We observed 567 new cases of MetS during follow-up. Participants who consumed nuts > or = 2 servings/week presented a 32% lower risk of developing MetS than those who never/almost never consumed (adjusted OR = 0.68, 95% CI 0.50, 0.92). The inverse association was stronger among participants who were health professionals. Nut consumption was significantly associated with lower risk of developing MetS after a 6-year follow-up period in a cohort of Spanish graduates.

  18. Ute Unit: Study Guide and Follow Up Activities.

    Science.gov (United States)

    North Conejos School District, Capulin, CO.

    The study guide and follow-up activities were designed primarily to give students a feeling of Ute life in the San Luis Valley in Colorado. The unit begins with six Southern Ute stories about the wolf and coyote, the race between the skunk and the coyote, the frog and the eagle, why the frog croaks, the bear (Que Ye Qat), and the two Indian…

  19. Follow-up of permanent hearing impairment in childhood.

    Science.gov (United States)

    Della Volpe, A; De Lucia, A; Pastore, V; Bracci Laudiero, L; Buonissimo, I; Ricci, G

    2016-02-01

    Programmes for early childhood childhood hearing impairment identification allows to quickly start the appropriate hearing aid fitting and rehabilitation process; nevertheless, a large number of patients do not join the treatment program. The goal of this article is to present the results of a strategic review of the strengths, weaknesses, opportunities and threats connected with the audiologic/prosthetic/language follow-up process of children with bilateral permanent hearing impairment. Involving small children, the follow-up includes the involvement of specialised professionals of a multidisciplinary team and a complex and prolonged multi-faced management. Within the framework of the Italian Ministry of Health project CCM 2013 "Preventing Communication Disorders: a Regional Program for Early Identification, Intervention and Care of Hearing Impaired Children", the purpose of this analysis was to propose recommendations that can harmonise criteria for outcome evaluation and provide guidance on the most appropriate assessment methods to be used in the follow-up course of children with permanent hearing impairment. © Copyright by Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale.

  20. Cherubism - A case report with long term follow up

    Directory of Open Access Journals (Sweden)

    Lakshmi V Chavali

    2011-01-01

    Full Text Available Cherubism is a rare non-neoplastic disease of the bone characterized by bilateral painless enlargement of the jaws giving a cherubic appearance to the patient. It is an autosomal dominant disorder but may occur sporadically. In this paper, we have tried to explain about the clinical, radiological and histopathologic features of cherubism by presenting a case study. A case study of a 7 year old male patient, who first presented with mandibular bilateral swellings to our department in 1998, has been presented. In-depth clinical, radiological and histopathologic examination was done. An extensive long-term follow-up till 11 years was maintained. When presented for the first time, radiological investigation showed characteristic multilocular lytic lesions of the mandible bilaterally. Histopathological examination of the biopsy specimen showed proliferating fibrous connective tissue interspersed by multinucleated giant cells. It was diagnosed as a case nonfamilial cherubism. Follow-up after 5 years showed involvement of the maxilla as well, which was then corrected by surgical methods. Upon follow up 11 years after the first presentation, it was seen that the lesion was regressing by itself and there was improvement in facial contour. The natural course of Cherubism through its progression, stabilization and involution of the disease after puberty, has been highlighted in this case. More, in-depth studies to understand the nature and the pathogenesis of this condition better are required.

  1. Baseline and follow-up laboratory monitoring of cardiovascular medications.

    Science.gov (United States)

    Tjia, Jennifer; Fischer, Shira H; Raebel, Marsha A; Peterson, Daniel; Zhao, Yanfang; Gagne, Shawn J; Gurwitz, Jerry H; Field, Terry S

    2011-09-01

    Laboratory monitoring of medications is typically used to establish safety prior to drug initiation and to detect drug-related injury following initiation. It is unclear whether black box warnings (BBWs) as well as evidence- and consensus-based clinical guidelines increase the likelihood of appropriate monitoring. To determine the proportion of patients newly initiated on selected cardiovascular medications with baseline assessment and follow-up laboratory monitoring and compare the prevalence of laboratory testing for drugs with and without BBWs and guidelines. This cross-sectional study included patients aged 18 years or older from a large multispecialty group practice who were prescribed a cardiovascular medication (angiotensin converting enzyme inhibitors, angiotensin II receptor blockers, amiodarone, digoxin, lipid-lowering agents, diuretics, and potassium supplements) between January 1 and July 31, 2008. The primary outcome measure was laboratory test ordering for baseline assessment and follow-up monitoring of newly initiated cardiovascular medications. The number of new users of each study drug ranged from 49 to 1757 during the study period. Baseline laboratory test ordering across study drugs ranged from 37.4% to 94.8%, and follow-up laboratory test ordering ranged from 20.0% to 77.2%. Laboratory tests for drugs with baseline laboratory assessment recommendations in BBWs were more commonly ordered than for drugs without BBWs (86.4% vs 78.0%, p BBW recommendations may improve monitoring.

  2. Recommendations for Follow-up Care for Gynecologic Cancer Survivors.

    Science.gov (United States)

    Elit, Laurie; Reade, Clare J

    2015-12-01

    Gynecologic cancer survivors are expected to increase in number over the coming years. This is attributable in part to an increased incidence of gynecologic malignancies as the population ages. Earlier detection and improved treatments will lead to improved survival. Women who have completed their cancer treatment and are disease-free enter a phase of follow-up care. This care can be provided by gynecologic oncologists, general gynecologists, or primary care practitioners, depending on local practices and geographic area. The key components of follow-up include complete history and physical examination. There should be judicious use of appropriate testing to detect disease recurrence, assessment, and management of therapy-related symptoms and provision of psychosocial support. Well-woman care and ongoing screening for other malignancies remain an important component of care that should not be overlooked. This review provides recommendations regarding follow-up care for women with gynecologic malignancies. There is very little high-quality evidence available to guide such care.

  3. Complications and Follow-up after Unprotected Carotid Artery Stenting

    International Nuclear Information System (INIS)

    Hauth, Elke A.M.; Drescher, Robert; Jansen, Christian; Gissler, H. Martin; Schwarz, Michael; Forsting, Michael; Jaeger, Horst J.; Mathias, Klaus D.

    2006-01-01

    Purpose. This prospective study was undertaken to determine the success rate, complications, and outcome of carotid artery stenting (CAS) without the use of cerebral protection devices. Methods. During 12 months, 94 high-grade stenoses of the carotid artery in 91 consecutive patients were treated. Sixty-six (70%) of the stenoses were symptomatic and 28 (30%) were asymptomatic. Results. In all 94 carotid stenoses CAS was successfully performed. During the procedure and within the 30 days afterwards, there were 2 deaths and 3 major strokes in the 66 symptomatic patients, resulting in a combined death and stroke rate of 5 of 66 (7%). Only one of these complications, a major stroke, occurred during the procedure. In the 6-month follow-up, one additional major stroke occurred in a originally symptomatic patient resulting in a combined death and stroke rate of 6 of 66 (10%) for symptomatic patients at 6 months. No major complications occurred in asymptomatic patients during the procedure or in the 6-month follow-up period. At 6 months angiographic follow-up the restenosis rate with a degree of >50% was 3 of 49 (6%) and the rate with a degree of ≥70% was 1 of 49 (2%). Conclusions. Cerebral embolization during CAS is not the only cause of the stroke and death rate associated with the procedure. The use of cerebral protection devices during the procedure may therefore not prevent all major complications following CAS

  4. Appraising the value of independent EIA follow-up verifiers

    Energy Technology Data Exchange (ETDEWEB)

    Wessels, Jan-Albert, E-mail: janalbert.wessels@nwu.ac.za [School of Geo and Spatial Sciences, Department of Geography and Environmental Management, North-West University, C/O Hoffman and Borcherd Street, Potchefstroom, 2520 (South Africa); Retief, Francois, E-mail: francois.retief@nwu.ac.za [School of Geo and Spatial Sciences, Department of Geography and Environmental Management, North-West University, C/O Hoffman and Borcherd Street, Potchefstroom, 2520 (South Africa); Morrison-Saunders, Angus, E-mail: A.Morrison-Saunders@murdoch.edu.au [School of Geo and Spatial Sciences, Department of Geography and Environmental Management, North-West University, C/O Hoffman and Borcherd Street, Potchefstroom, 2520 (South Africa); Environmental Assessment, School of Environmental Science, Murdoch University, Australia. (Australia)

    2015-01-15

    Independent Environmental Impact Assessment (EIA) follow-up verifiers such as monitoring agencies, checkers, supervisors and control officers are active on various construction sites across the world. There are, however, differing views on the value that these verifiers add and very limited learning in EIA has been drawn from independent verifiers. This paper aims to appraise how and to what extent independent EIA follow-up verifiers add value in major construction projects in the developing country context of South Africa. A framework for appraising the role of independent verifiers was established and four South African case studies were examined through a mixture of site visits, project document analysis, and interviews. Appraisal results were documented in the performance areas of: planning, doing, checking, acting, public participating and integration with other programs. The results indicate that independent verifiers add most value to major construction projects when involved with screening EIA requirements of new projects, allocation of financial and human resources, checking legal compliance, influencing implementation, reporting conformance results, community and stakeholder engagement, integration with self-responsibility programs such as environmental management systems (EMS), and controlling records. It was apparent that verifiers could be more creatively utilized in pre-construction preparation, providing feedback of knowledge into assessment of new projects, giving input to the planning and design phase of projects, and performance evaluation. The study confirms the benefits of proponent and regulator follow-up, specifically in having independent verifiers that disclose information, facilitate discussion among stakeholders, are adaptable and proactive, aid in the integration of EIA with other programs, and instill trust in EIA enforcement by conformance evaluation. Overall, the study provides insight on how to harness the learning opportunities

  5. Appraising the value of independent EIA follow-up verifiers

    International Nuclear Information System (INIS)

    Wessels, Jan-Albert; Retief, Francois; Morrison-Saunders, Angus

    2015-01-01

    Independent Environmental Impact Assessment (EIA) follow-up verifiers such as monitoring agencies, checkers, supervisors and control officers are active on various construction sites across the world. There are, however, differing views on the value that these verifiers add and very limited learning in EIA has been drawn from independent verifiers. This paper aims to appraise how and to what extent independent EIA follow-up verifiers add value in major construction projects in the developing country context of South Africa. A framework for appraising the role of independent verifiers was established and four South African case studies were examined through a mixture of site visits, project document analysis, and interviews. Appraisal results were documented in the performance areas of: planning, doing, checking, acting, public participating and integration with other programs. The results indicate that independent verifiers add most value to major construction projects when involved with screening EIA requirements of new projects, allocation of financial and human resources, checking legal compliance, influencing implementation, reporting conformance results, community and stakeholder engagement, integration with self-responsibility programs such as environmental management systems (EMS), and controlling records. It was apparent that verifiers could be more creatively utilized in pre-construction preparation, providing feedback of knowledge into assessment of new projects, giving input to the planning and design phase of projects, and performance evaluation. The study confirms the benefits of proponent and regulator follow-up, specifically in having independent verifiers that disclose information, facilitate discussion among stakeholders, are adaptable and proactive, aid in the integration of EIA with other programs, and instill trust in EIA enforcement by conformance evaluation. Overall, the study provides insight on how to harness the learning opportunities

  6. Automated telecommunication to obtain longitudinal follow-up in a multicenter cross-sectional COPD study.

    Science.gov (United States)

    Stewart, Jeffrey I; Moyle, Sarah; Criner, Gerard J; Wilson, Carla; Tanner, Ron; Bowler, Russell P; Crapo, James D; Zeldin, Robert K; Make, Barry J; Regan, Elizabeth A; For The Copdgene Investigators

    2012-08-01

    It can be challenging to maintain longitudinal follow-up of subjects in clinical studies. COPDGene is a multicenter, observational study designed to identify genetic factors associated with COPD and to characterize COPD-related phenotypes. To obtain follow-up data on patient's vital status and outcomes, the COPDGene Longitudinal Follow-up (LFU) Program was developed to supplement its parent study. We used a telecommunication system that employed automated telephone contact or web-based questions to obtain longitudinal follow-up data in our subjects. A branching questionnaire asked about exacerbations, new therapies, smoking status, development of co-morbid conditions, and general health status. Study coordinators contacted subjects who did not respond to one of the automated methods. We enrolled 10,383 subjects in the COPDGene study. As of August 29, 2011, 7,959 subjects completed 19,955 surveys. On the first survey, 68.8% of subjects who completed their survey did so by electronic means, while 31.3% required coordinator phone follow-up. On each subsequent survey the number of subjects who completed their survey by electronic means increased, while the number of subjects who required coordinator follow-up decreased. Despite many of the patients in the cohort being chronically ill and elderly, there was broad acceptance of the system with over half the cohort using electronic response methods. The COPDGene LFU Study demonstrated that telecommunications was an effective way to obtain longitudinal follow-up of subjects in a large multicenter study. Web-based and automated phone contacts are accepted by research subjects and could serve as a model for LFU in future studies.

  7. Radio afterglow of the jetted tidal disruption event Swift J1644+57

    Directory of Open Access Journals (Sweden)

    Mimica P.

    2012-12-01

    Full Text Available The recent transient event Swift J1644+57 has been interpreted as resulting from a relativistic outflow, powered by the accretion of a tidally disrupted star onto a supermassive black hole. This discovery of a new class of relativistic transients opens new windows into the study of tidal disruption events (TDEs and offers a unique probe of the physics of relativistic jet formation and the conditions in the centers of distant quiescent galaxies. Unlike the rapidly-varying γ/X-ray emission from Swift J1644+57, the radio emission varies more slowly and is well modeled as synchrotron radiation from the shock interaction between the jet and the gaseous circumnuclear medium (CNM. Early after the onset of the jet, a reverse shock propagates through and decelerates the ejecta released during the first few days of activity, while at much later times the outflow approaches the self-similar evolution of Blandford and McKee. The point at which the reverse shock entirely crosses the earliest ejecta is clearly observed as an achromatic break in the radio light curve at t ≈ 10 days. The flux and break frequencies of the afterglow constrain the properties of the jet and the CNM, including providing robust evidence for a narrowly collimated jet. I briefly discuss the implications of Swift J1644+57 for the fraction of TDEs accompanied by relativistic jets; the physics of jet formation more broadly; and the prospects for detecting off-axis TDE radio emission, either via follow-up observations of TDE candidates discovered at other wavelengths or blindly with upcoming wide-field radio surveys. The radio rebrightening observed months after the onset of the jet remains a major unsolved mystery, the resolution of which may require considering a jet with more complex (temporal or angular structure.

  8. MRI of cerebral rheumatoid pachymeningitis: report of two cases with follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Cellerini, M.; Gabbrielli, S. [Florence Univ. (Italy). Dept. of Clinical Pathophysiology; Maddali Bongi, S.; Cammelli, D. [Section of Rheumatology, Department of Internal Medicine, School of Medicine, Univ. of Florence (Italy)

    2001-02-01

    We report the clinical and neuroradiological features of cerebral rheumatoid pachymeningitis with 1 year follow-up in two patients. MRI of the head enabled noninvasive diagnosis of both the meningeal abnormality and its complications, consisting of hypertensive hydrocephalus and superior sagittal sinus thrombosis, respectively. Dural sinus thrombosis, very uncommon in rheumatoid arthritis, was confirmed by phase-contrast MRA. Worsening of the pachymeningitis at follow-up was observed in both patients despite regression or stability of the clinical picture and long-term therapy. (orig.)

  9. Sleep During Menopausal Transition: A 6-Year Follow-Up.

    Science.gov (United States)

    Lampio, Laura; Polo-Kantola, Päivi; Himanen, Sari-Leena; Kurki, Samu; Huupponen, Eero; Engblom, Janne; Heinonen, Olli J; Polo, Olli; Saaresranta, Tarja

    2017-07-01

    Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective 6-year follow-up study was designed to evaluate the changes in sleep stages and sleep continuity that occur in women during menopausal transition. Sixty women (mean age 46.0 years, SD 0.9) participated. All women were premenopausal at baseline, and at the 6-year follow-up, women were in different stages of menopausal transition. Polysomnography was used to study sleep architecture at baseline and follow-up. The effects of aging and menopause (assessed as change in serum follicle-stimulating hormone [S-FSH]) on sleep architecture were evaluated using linear regression models. After controlling for body mass index, vasomotor, and depressive symptoms, aging of 6 years resulted in shorter total sleep time (B -37.4, 95% confidence interval [CI] -71.5 to (-3.3)), lower sleep efficiency (B -6.5, 95%CI -12.7 to (-0.2)), as well as in increased transitions from slow-wave sleep (SWS) to wakefulness (B 1.0, 95%CI 0.1 to 1.9), wake after sleep onset (B 37.7, 95%CI 12.5 to 63.0), awakenings per hour (B 1.8, 95%CI 0.8 to 2.8), and arousal index (B 2.3, 95%CI 0.1 to 4.4). Higher S-FSH concentration in menopausal transition was associated with increased SWS (B 0.09, 95%CI 0.01 to 0.16) after controlling for confounding factors. A significant deterioration in sleep continuity occurs when women age from 46 to 52 years, but change from premenopausal to menopausal state restores some SWS. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  10. Long-Term Follow-Up of Lateral Canthal Resuspension.

    Science.gov (United States)

    Ramesh, Sathyadeepak; Gupta, Adit; Rootman, Daniel Benson; Goldberg, Robert Alan

    2018-01-01

    To evaluate the long-term results of lateral canthal resuspension over time. A cohort study of adults (n = 25, 45 eyelids) undergoing lateral canthal resuspension. Marginal reflex distance 2 (MRD2), inferior scleral show, lateral canthal height, lateral canthal angle, horizontal palpebral aperture, and lateral scleral triangle area were measured preoperatively and at postoperative week 1, month 3, and the final follow-up visit. Minimum follow-up time was 6 months (mean, 15.1 months). At the final follow-up visit, MRD2 decreased by 0.41 ± 0.14 mm, inferior scleral show decreased by 0.27 ± 0.05 mm, and lateral canthal height increased by 0.81 ± 0.15 mm. The overall function of time was found to be significant for change in MRD2 (P < 0.01). In multiple comparisons, all time point values were significantly different from one another (Bonferroni corrected, P < 0.05), except for 3 months and the final position, which were not. Similarly, the overall effect of time on lateral canthus position was also significant (P < 0.01). All time points were significantly different from one another (Bonferroni corrected, P < 0.05). The overall effect of time on inferior scleral show was also significant (P < 0.01). Differences were significant from preoperative to final postoperative position, although the other time points were not significant (Bonferroni corrected, P < 0.05). No complications were noted. Minimally invasive lateral canthal resuspension provides durable, albeit modest, improvements in MRD2, inferior scleral show, and lateral canthal height without significantly changing lateral canthal angle, horizontal palpebral aperture, or lateral scleral triangle area. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

  11. Cervicomedullary astrocytomas of childhood: clinical and imaging follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Young Poussaint, T.; Yousuf, N.; Barnes, P.D. [Division of Neuroradiology, Department of Radiology, Children`s Hospital, Boston, MA (United States); Anthony, D.C. [Department of Pathology, Children`s Hospital, Boston, MA (United States); Zurakowski, D. [Department of Research Computing and Biostatistics, Children`s Hospital, Boston, MA (United States); Scott, R.M. [Department of Neurosurgery, Children`s Hospital, Boston, MA (United States); Tarbell, N.J. [Head, Radiation Oncology Unit, Massachusetts General Hospital, Boston, MA (United States)

    1999-09-01

    Background. Cervicomedullary astrocytomas are a unique subset of brainstem tumors in children because they have a good prognosis when compared to the pontine subset of brainstem gliomas. Objective. To review the clinical and imaging findings in a series of children with cervicomedullary astrocytomas as to diagnosis and management. Materials and methods. A retrospective review of eleven children (six females, five males, age range: 10 days-18 years; mean = 7 years) with cervicomedullary tumors was done including the clinical presentation, imaging studies (MR: eleven, CT and MR: four), surgical findings, pathological results, and follow-up clinical and imaging findings (range: 0.2-11 years; mean = 5.2 years). Results. Symptoms and signs were delayed and protracted, often occurring over months to years (mean = 2.3 years, range 0.5-7 years). The tumors expanded the dorsal medulla and involved the upper cervical spinal cord (mean maximum tumor diameter = 4.4 cm). Only three patients had hydrocephalus. In three of four cases the tumor was not seen on CT. On MR, the majority of the tumors were T1 hypointense and T2 hyperintense. Treatment consisted of surgery only in six patients, surgery and radiation therapy in four, and surgery, chemotherapy, and radiation in one. There was recurrent local disease in four patients and on follow-up metastatic disease in the brain in one. On follow-up the majority of the patients are alive and stable (mean = 5.2 years, range 0.2-11 years). There has been one death. The majority of tumors were pilocytic astrocytomas. Conclusion. Cervicomedullary tumors are a unique subset of brainstem gliomas in childhood that present with a long duration of symptoms and a greater long-term survival than pontine gliomas. (orig.) With 4 figs., 2 tabs., 21 refs.

  12. Latex allergy in children: a follow-up study.

    Science.gov (United States)

    Diéguez Pastor, M C; Antón Girones, M; Blanco, R; Pulido, Z; Muriel, A; de la Hoz Caballer, B

    2006-01-01

    Natural rubber latex allergy is an important health problem. Multiple contacts with latex in childhood are a risk factor. Many aspects of this disease are still unknown, one of which is the clinical outcome of these children. The aim of this study was to evaluate the clinical and epidemiological features of latex allergy and compliance with latex avoidance instructions in allergic children. Seventeen consecutive patients with a history of latex allergy, fruit allergy or chronic urticaria were selected. The patients underwent a skin prick test and determination of specific-IgE to latex at the start and at end of the study (median follow-up: 3 years). At diagnosis, patients with a positive result to one of the tests and a clinical history of latex allergy were considered allergic; patients with a positive test but without a clinical history suggestive of allergy were considered sensitized. These children were given latex avoidance instructions. Eleven children (64.7 %) were classified as allergic and 6 (35.3 %) as sensitized. Five patients had undergone latex-free surgery after diagnosis without incident. During follow-up, 11 patients (8 allergic and 3 sensitized) had contact with latex. Contact occurred in the home in 10 children, and all were symptomatic. Specific-IgE levels to latex at the end of the study were significantly higher in patients who had contact with latex during the follow-up period than in those without latex contact. Strict compliance with latex avoidance instructions is essential both inside and outside the hospital. Greater emphasis should be placed on reducing latex exposure in the home and school environments, as such contact could maintain positive IgE-antibody levels.

  13. DESGW: Optical Follow-up of BBH LIGO-Virgo Events with DECam

    Energy Technology Data Exchange (ETDEWEB)

    Butler, Robert E. [Indiana U.; Soares-Santos, M. [Brandeis U.; Annis, j. [Fermilab; Herner, K. [Fermilab

    2017-12-14

    The DESGW program is a collaboration between members of the Dark Energy Survey, the wider astronomical community, and the LIGO-Virgo Collaboration to search for optical counterparts of gravitational wave events, such as those expected from binary neutron star mergers or neutron star-black hole mergers. While binary black hole (BBH) events are not expected to produce an electromagnetic (EM) signature, emission is certainly not impossible. The DESGW program has performed follow-up observations of four BBH events detected by LIGO in order to search for any possible EM counterpart. Failure to nd such counterparts is still relevant in that it produces limits on optical emission from such events. This is a review of follow-up results from O1 BBH events and a discussion of the status of ongoing uniform re-analysis of all BBH events that DESGW has followed up to date.

  14. Laparoscopic Hill repair: 25-year follow-up.

    Science.gov (United States)

    Park, Yeseul; Aye, Ralph W; Watkins, Jeffrey R; Farivar, Alex S; Louie, Brian E

    2018-03-30

    The open Hill repair for gastroesophageal reflux disease and hiatal hernia is remarkably durable, with a median 10-year reoperation rate of only 3% and satisfaction of 93%. No long-term data exist for the laparoscopic Hill repair (LHR). Patients who underwent primary LHR at Swedish Medical Center for reflux and/or hiatal hernia at least 5 years earlier (1992-2010) were identified from an IRB-approved database. There were 727 patients who met inclusion criteria, including 648 undergoing repair for reflux and 79 for paraesophageal hernia. Two questionnaires were administered via mail to evaluate long-term quality of life using validated GERD-HRQL, Swallowing score, and global satisfaction score. Outcomes were defined by GERD-HRQL score, Swallowing score, resumption of proton pump inhibitor (PPI) therapy, need for reoperation, and global satisfaction with overall results. Two hundred forty-two patients completed and returned the survey (226 lost to follow-up, 90 deceased, 3 denied undergoing LHR, 166 non-responders), of which 52% were male. The average age at the time of surgery was 49.5 years. Median follow-up was 18.5 years (range 6.2-24.7). The average GERD-HRQL score (7.1) and the average Swallowing score (39.9) both indicated excellent symptomatic outcomes. 30% of patients are using daily PPIs. 24 patients (9.9%) required reoperation for failure during the follow-up period, 21 in the reflux group and 3 in the paraesophageal hernia group. Overall, 85% reported good to excellent results, and 76% would recommend the operation. LHR shows excellent long-term durability and quality of life similar to the open Hill repair, with 85% good to excellent results at a median follow-up of 19 years and a reoperation rate under 10%. It is surmised that Hill suture fixation of the gastroesophageal junction to the preaortic fascia may confer unique structural integrity compared to other repairs.

  15. Urological outcome after myelomeningocele: 20 years of follow-up

    DEFF Research Database (Denmark)

    Thorup, Jørgen Mogens; Biering-Sorensen, Fin; Cortes, Dina

    2011-01-01

    at follow-up; seven (14%) had normal total renal function but unilateral deteriorated kidney, and eight individuals (15%) had deteriorated kidney function. Adult individuals with bilateral kidney deterioration had a significant higher frequency of diagnosed detrusor overactivity at childhood urodynamics (63...... intermittent catheterization. CONCLUSIONS: Overall, 15% of patients had impairment of kidney function and 48% were urinary continent. Considering the present age distribution of the present study population, this figure appears to be comparable to the data in the literature. Urodynamic findings in childhood...

  16. Primary cemented total hip arthroplasty: 10 years follow-up

    Directory of Open Access Journals (Sweden)

    Nath Rajendra

    2010-01-01

    Full Text Available Background: Primary cemented total hip arthroplasty is a procedure for non-traumatic and traumatic affections of the hip. Long term follow-up is required to assess the longevity of the implant and establish the procedure. Indo-Asian literature on long term result of total hip arthroplasty is sparse. We present a 10-year follow-up of our patients of primary cemented total hip arthroplasty. Materials and Methods: We operated 31 hips in 30 patients with primary cemented total hip arthroplasty. We followed the cases for a minimum period of 10 years with a mean follow-up period of 12.7 years. The mean age of the patients was 60.7 years (range 37-82 yrs male to female ratio was 2:1. The clinical diagnoses included - avascular necrosis of femoral head (n=15, sero positive rheumatoid arthritis (n=5, seronegative spondylo-arthropathy (n=4, neglected femoral neck fractures (n=3, healed tubercular arthritis (n=2 and post traumatic osteoarthritis of hip (n=2. The prostheses used were cemented Charnley′s total hip (n=12 and cemented modular prosthesis (n=19. The results were assessed according to Harris hip score and radiographs taken at yearly intervals. Results: The mean follow-up is 12.7 yrs (range 11-16 yrs Results in all operated patients showed marked improvement in Harris hip score from preoperative mean 29.2 to 79.9 at 10 years or more followup. However, the non-inflammatory group showed more sustained long term improvement as compared to the inflammatory group, as revealed by the Harris hip score. Mean blood loss was 450ml (±3.7 ml, mean transfusion rate was 1.2 units (±.3. The complications were hypotension (n=7, shortening> 1.5 cm (n=9, superficial infection (n=2 and malposition of prosthesis (n=1. Conclusion: The needs of Indian Asian patients, vary from what is discussed in literature. The pain tolerance is greater than western population and financial constraints are high. Thus revision surgery among Indian-Asian patients is less compared

  17. Shillapoo Wildlife Area 2007 Follow-up HEP Report.

    Energy Technology Data Exchange (ETDEWEB)

    Ashley, Paul R.

    2008-03-01

    In April and May 2007 the Regional HEP Team (RHT) conducted a follow-up HEP analysis on the Egger (612 acres) and Herzog (210 acres) parcels located at the north end of the Shillapoo Wildlife Area. The Egger and Herzog parcels have been managed with Bonneville Power Administration funds since acquired in 1998 and 2001 respectively. Slightly more than 936 habitat units (936.47) or 1.14 HUs per acre was generated as an outcome of the 2007 follow-up HEP surveys. Results included 1.65 black-capped chickadee HUs, 280.57 great blue heron HUs, 581.45 Canada goose HUs, 40 mallard HUs, and 32.80 mink HUs. Introduction A follow-up Habitat Evaluation Procedures (HEP) (USFWS 1980) analysis was conducted by the Columbia Basin Fish and Wildlife Authority's (CBFWA) Regional HEP Team (RHT) during April and May 2007 to document changes in habitat quality and to determine the number of habitat units (HUs) to credit Bonneville Power Administration (BPA) for providing operation and maintenance (O&M) funds since WDFW acquired the parcels. The 2007 follow-up HEP evaluation was limited to Shillapoo Wildlife Area (SWA) parcels purchased with Bonneville Power Administration funds. D. Budd (pers. comm.) reported WDFW purchased the 612 acre Egger Farms parcel on November 2, 1998 for $1,737,0001 and the 210 acre Herzog acquisition on June 21, 2001 for $500,000 with Memorandum of Agreement funds (BPA and WDFW 1996) as partial fulfillment of BPA's wildlife mitigation obligation for construction of Bonneville and John Day Dams (Rasmussen and Wright 1989). Anticipating the eventual acquisition of the Egger and Herzog properties, WDFW conducted HEP surveys on these lands in 1994 to determine the potential number of habitat units to be credited to BPA. As a result, HEP surveys and habitat unit calculations were completed as much as seven years prior to acquiring the sites. The term 'Shillapoo Wildlife Area' will be used to describe only the Herzog and Egger parcels in this

  18. Follow-up study of memory deficits after ECT.

    Science.gov (United States)

    Shellenberger, W; Miller, M J; Small, I F; Milstein, V; Stout, J R

    1982-06-01

    Twenty-four patients received ECT induced by either alternating sine wave or brief pulsed-square wave stimulus and were evaluated at follow-up for clinical functioning and subjective memory loss. The hypothesis of less memory loss in the group receiving a weaker stimulus (pulsed-square wave) was not supported. The two treatment groups and a group of controls showed no significant differences on the memory test. On measures of clinical functioning the sine wave group scored better on every measure than the square wave group, although not significantly better.

  19. Follow-up of young road accident victims.

    Science.gov (United States)

    Gillies, Marjorie L; Barton, Joanne; Di Gallo, Alain

    2003-10-01

    The aim of this study was to follow-up a group of children and young people previously examined for psychological sequelae following road traffic accidents. The group was assessed 18-month postaccident to assess the severity of continuing symptoms and examine any emergence of delayed onset of posttraumatic stress reactions. Participants (N = 31) completed the Revised Impact of Event Scale and the Child Posttraumatic Stress Reaction Index. Parents completed the Child Behavior Check-List and participated in a semistructured interview. Symptoms of PTSD were noted in a quarter of participants as was delayed onset of symptoms. The role of avoidance in symptom reporting and continuing disorder is discussed.

  20. Automated medical follow-up and delayed industrial risks

    International Nuclear Information System (INIS)

    Smith, M.E.

    In response to increasing demand for human data to identify social, environmental, and occupational influences upon health, Statistics Canada has been organizing existing files of vital and health records to facilitate such studies on a national scale. In particular, the development of a Canadian Mortality Data Base file, the initiation of the National Cancer Incidence system, and the development of new computer techniques have helped reduce the cost and increase the scale and efficiency of automated medical follow-up to produce statistics of sickness or death attributable to environmental factors. Specific occupational studies now in progress serve to illustrate the methods, practical difficulties, potential size, and products from such investigations

  1. Radio Follow-up of Gravitational-wave Triggers during Advanced LIGO O1

    Science.gov (United States)

    Palliyaguru, N. T.; Corsi, A.; Kasliwal, M. M.; Cenko, S. B.; Frail, D. A.; Perley, D. A.; Mishra, N.; Singer, L. P.; Gal-Yam, A.; Nugent, P. E.; Surace, J. A.

    2016-10-01

    We present radio follow-up observations carried out with the Karl G. Jansky Very Large Array during the first observing run (O1) of the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO). A total of three gravitational-wave triggers were followed-up during the ≈ 4 months of O1, from 2015 September to 2016 January. Two of these triggers, GW150914 and GW151226, are binary black hole (BH) merger events of high significance. A third trigger, G194575, was subsequently declared as an event of no interest (I.e., a false alarm). Our observations targeted selected optical transients identified by the intermediate Palomar Transient Factory in the Advanced LIGO error regions of the three triggers, and a limited region of the gravitational-wave localization area of G194575 not accessible to optical telescopes due to Sun constraints, where a possible high-energy transient was identified. No plausible radio counterparts to GW150914 and GW151226 were found, in agreement with expectations for binary BH mergers. We show that combining optical and radio observations is key to identifying contaminating radio sources that may be found in the follow-up of gravitational-wave triggers, such as emission associated with star formation and active galactic nuclei. We discuss our results in the context of the theoretical predictions for radio counterparts to gravitational-wave transients, and describe our future plans for the radio follow-up of Advanced LIGO (and Virgo) triggers.

  2. Assessment of diabetics' follow-up in a primary care setting, Riyadh, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Thamer A. Alsulaiman

    2015-01-01

    Conclusion: Deficiencies were observed regarding the diabetics' annual follow-up at our clinic during the year 2013. A more consistent approach is needed in requesting the lab investigations and referrals for diabetics in order to meet the clinic's target. Repeat auditing in a year's time is recommended to monitor improvement.

  3. Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up

    NARCIS (Netherlands)

    van der Valk, Mirthe E.; Mangen, Marie-Josée J.; Severs, Mirjam; van der Have, Mike; Dijkstra, Gerard; van Bodegraven, Ad A.; Fidder, Herma H.; de Jong, Dirk J.; van der Woude, C. Janneke; Romberg-Camps, Mariëlle J. L.; Clemens, Cees H. M.; Jansen, Jeroen M.; van de Meeberg, Paul C.; Mahmmod, Nofel; van der Meulen-de Jong, Andrea E.; Ponsioen, Cyriel Y.; Bolwerk, Clemens; Vermeijden, J. Reinoud; Siersema, Peter D.; Leenders, Max; Oldenburg, Bas

    2016-01-01

    With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver. We aimed to explore the evolution of IBD-related costs over two years of follow-up. In total 1,307

  4. [Colonoscopy in the long-term follow-up of surgical anastomoses of the large intestine].

    Science.gov (United States)

    Rossini, F P; Ferrari, A; Roatta, L; Presti, F; Boido, C

    1976-10-15

    On the bases of personal experience the importance of endoscopic examination of the colon in the follow-up of patients who have been subjected to resection of the large intestine is emphasized. Fibercoloscopy permits direct observation of "high" surgical anastomoses, which are inaccessible for examination with rigid rectosigmoidoscope, and thus opens the way to precise diagnosis and a correct therapeutic approach.

  5. 12-month follow-up study of drug treatment in pathological gamblers: a primary outcome study.

    Science.gov (United States)

    Dannon, Pinhas N; Lowengrub, Katherine; Musin, Ernest; Gonopolsky, Yehudit; Kotler, Moshe

    2007-12-01

    Pathological gambling (PG) is a relatively common and highly disabling impulse control disorder. A range of psychotherapeutic agents including selective serotonin reuptake inhibitors, antiepileptic drugs, and opioid antagonists are shown to be effective in the short-term treatment of PG. The use of a wide range of pharmacological treatments for PG is consistent with the observation that PG shares features of obsessive-compulsive spectrum disorders, impulse control disorders, and addictive disorders. The aim of the study is to assess the rate of relapse in treatment-responder pathological gamblers after discontinuation of the active treatment. Our study sample was composed of 43 male pathological gamblers who had been full responders to 1 of 4 drug treatment regimens (fluvoxamine, topiramate, bupropion SR, or naltrexone) from several previous acute open-label (12-week) comparison studies. Full response was defined as the absence of gambling for a 1-month duration together with improvement on the Clinical Global Improvement scale. The 43 full responders were then followed prospectively for an additional 9 months, which included a 3-month open-label continuation phase and a 6-month medication-free follow-up phase. Follow-up visits were performed on a monthly basis throughout the duration of study. At every follow-up visit, a comprehensive psychiatric diagnostic evaluation was performed on all patients, and patients were assessed for symptoms of gambling using a self-report instrument and collateral family reports. The Clinical Global Impression Improvement scale was also administered at every follow-up visit. Raters were blind to the previous drug treatment. Most patients did not relapse during the 6-month medication-free follow-up phase. Three of 6 patients with fluvoxamine, 3 of 9 with topiramate, 7 of 18 with bupropion SR, and 4 of 10 with naltrexone relapsed. Relapse was strictly defined as gambling behavior at any time during the 6-month medication-free follow-up

  6. Follow up study of Alzheimer's type dementia with computed tomography

    International Nuclear Information System (INIS)

    Hirata, Nobuhide

    1987-01-01

    In 54 patients who were diagnosed as having Alzheimer's type dementia based on the Diagnostic and Statistical Manual of Mental Disorders, III, cranial computed tomography (CT) scans were obtained before and after their follow-up study ranging from 6 to 24 months (mean 15.4 +- 4.7 months). Cerebrospinal percentage and CT density in various regions of interest were examined. Six patients died during the study. Comparison of the group of the deceased (Group I) with the group of survivors (Group II) revealed: (1) there was no difference in average age and the degree of mental disorder at first presentation; (2) Group I had decreased activities of daily living; and (3) CT density was significantly decreased in the bilateral lateral and frontal lobes in Group I. As for Group II, decreased CT numbers were noticeable during the follow-up period in the frontal lobe, parietal lobe, and caudate nucleus in the group evaluated as aggravated, as compared with the group evaluated as unchanged. (Namekawa, K.)

  7. CT follow-up after radiation therapy for pituitary adenomas

    International Nuclear Information System (INIS)

    Rush, S.C.; Newall, J.

    1988-01-01

    Between 1973 and 1985, 105 patients received radiation therapy as all or part of their treatment for pituitary tumor at the New York University Medical Center. Of these, 48 patients underwent computed tomography (CT) at a minimum of 2 years following treatment, with detailed reports available for analysis of tumor regression. There were 28 men with a median age of 46 years (range, 18-71 years) and 20 women with a median age of 53 years (range, 28-80 years). Tumors were classified as secretory in 23 patients, nonsecretory in 21, and undetermined in four. Sixteen patients were treated with radiation therapy alone, 23 patients with surgery and radiation therapy, and the other with bromocriptine and radiation therapy, with or without surgery. With a median follow-up of 5 years (range, 2-14 years), 16 patients developed an empty sella, 25 patients had residual sellar mass, and seven patients had persistent extrasellar components or no change in their intrasellar mass. Among patients who did not have hypopituitarism at the inception of radiation therapy, five of 13 with empty sellas and 12 of 22 with residual mass subsequently required therapy. The authors conclude that residual mass is commonly found in long-term follow-up after radiation therapy, that isolated imaging studies revealing such findings after treatment in no way herald a diagnosis of recurrence, and that hypopituitarism following pituitary radiation therapy does not correlate with the ablation or persistence of tissue within the sella

  8. ESUR guidelines: ovarian cancer staging and follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Forstner, Rosemarie [Paracelsus Medical University, Department of Radiology, Landeskliniken Salzburg, Salzburg (Austria); Sala, Evis [University of Cambridge, Cambridge University Hospitals, NHS Foundation Trust, Cambridge (United Kingdom); Kinkel, Karen [Geneva University Hospital, Clinique des Grangettes, Geneva (Switzerland); Spencer, John A. [St James' s University Hospital, Leeds (United Kingdom)

    2010-12-15

    To design clear guidelines for the staging and follow-up of patients with ovarian cancer, and to provide the radiologist with a framework for use in multidisciplinary conferences. Guidelines for ovarian cancer staging and follow-up were defined by the female imaging subcommittee of the ESUR (European Society of Urogenital Radiology) based on the expert consensus of imaging protocols of 12 leading institutions and a critical review of the literature. Computed tomography (CT) with coverage of the base of the lungs to the inguinal region is regarded as the imaging technique of choice for preoperative staging. Critical diagnostic criteria are presented and the basis for a structured report for preoperative staging is outlined. Following primary treatment for ovarian cancer, clinical assessment and CA-125 are routinely used to monitor patients. For suspected recurrence, CT remains the imaging modality of choice, with positron emission tomography (PET)/CT emerging as the optimal imaging technique for suspected recurrence, particularly in patients with negative CT or magnetic resonance imaging (MRI). CT is the imaging modality of choice for preoperative staging and detection of recurrence in patients with ovarian cancer. (orig.)

  9. Gastric and Duodenal Stents: Follow-Up and Complications

    International Nuclear Information System (INIS)

    Pinto Pabon, Isabel Teresa; Paul Diaz, Laura; Ruiz de Adana, Juan Carlos; Lopez Herrero, Julio

    2001-01-01

    Purpose: To assess the efficacy of self-expanding metallic stents in treating inoperable gastric and duodenal stenoses during follow-up and to evaluate the complications encountered.Methods: A total of 31 patients suffering from gastroduodenal obstruction (29 malignant, 2 benign) were treated with a self-expanding metallic stent (Wallstent). In 24 cases insertion was by the peroral route, in seven cases via gastrostomy.Results: All the strictures were successfully negotiated under fluoroscopic guidance without having to resort to endoscopy. A total of 27 patients (87%) were able to resume a regular diet, a soft diet, or a liquid diet orally. Complications included one case of stent malpositioning, one case of leakage of ascitic fluid through the gastrostomy orifice, one case of perforation and fistula to the biliary tree, and two cases of hematemesis. In two patients (6%) additional stents were implanted to improve patency. In all patients follow-up was maintained until death. Recurrence of symptoms immediately before death occurred in seven cases (23%). Mean survival time of patients was 13.3 weeks (SE ± 4.6).Conclusions: The deployment of gastroduodenal stents resulted in good palliation of inoperable gastric and duodenal stenoses. Certain technical aspects, e.g., adaptation of stents to bowel morphology, is critical to proper stent function and avoidance of complications

  10. A predictive scoring instrument for tuberculosis lost to follow-up outcome

    Science.gov (United States)

    2012-01-01

    Background Adherence to tuberculosis (TB) treatment is troublesome, due to long therapy duration, quick therapeutic response which allows the patient to disregard about the rest of their treatment and the lack of motivation on behalf of the patient for improved. The objective of this study was to develop and validate a scoring system to predict the probability of lost to follow-up outcome in TB patients as a way to identify patients suitable for directly observed treatments (DOT) and other interventions to improve adherence. Methods Two prospective cohorts, were used to develop and validate a logistic regression model. A scoring system was constructed, based on the coefficients of factors associated with a lost to follow-up outcome. The probability of lost to follow-up outcome associated with each score was calculated. Predictions in both cohorts were tested using receiver operating characteristic curves (ROC). Results The best model to predict lost to follow-up outcome included the following characteristics: immigration (1 point value), living alone (1 point) or in an institution (2 points), previous anti-TB treatment (2 points), poor patient understanding (2 points), intravenous drugs use (IDU) (4 points) or unknown IDU status (1 point). Scores of 0, 1, 2, 3, 4 and 5 points were associated with a lost to follow-up probability of 2,2% 5,4% 9,9%, 16,4%, 15%, and 28%, respectively. The ROC curve for the validation group demonstrated a good fit (AUC: 0,67 [95% CI; 0,65-0,70]). Conclusion This model has a good capacity to predict a lost to follow-up outcome. Its use could help TB Programs to determine which patients are good candidates for DOT and other strategies to improve TB treatment adherence. PMID:22938040

  11. Results of remote follow-up and monitoring in young patients with cardiac implantable electronic devices.

    Science.gov (United States)

    Silvetti, Massimo S; Saputo, Fabio A; Palmieri, Rosalinda; Placidi, Silvia; Santucci, Lorenzo; Di Mambro, Corrado; Righi, Daniela; Drago, Fabrizio

    2016-01-01

    Remote monitoring is increasingly used in the follow-up of patients with cardiac implantable electronic devices. Data on paediatric populations are still lacking. The aim of our study was to follow-up young patients both in-hospital and remotely to enhance device surveillance. This is an observational registry collecting data on consecutive patients followed-up with the CareLink system. Inclusion criteria were a Medtronic device implanted and patient's willingness to receive CareLink. Patients were stratified according to age and presence of congenital/structural heart defects (CHD). A total of 221 patients with a device - 200 pacemakers, 19 implantable cardioverter defibrillators, and two loop recorders--were enrolled (median age of 17 years, range 1-40); 58% of patients were younger than 18 years of age and 73% had CHD. During a follow-up of 12 months (range 4-18), 1361 transmissions (8.9% unscheduled) were reviewed by technicians. Time for review was 6 ± 2 minutes (mean ± standard deviation). Missed transmissions were 10.1%. Events were documented in 45% of transmissions, with 2.7% yellow alerts and 0.6% red alerts sent by wireless devices. No significant differences were found in transmission results according to age or presence of CHD. Physicians reviewed 6.3% of transmissions, 29 patients were contacted by phone, and 12 patients underwent unscheduled in-hospital visits. The event recognition with remote monitoring occurred 76 days (range 16-150) earlier than the next scheduled in-office follow-up. Remote follow-up/monitoring with the CareLink system is useful to enhance device surveillance in young patients. The majority of events were not clinically relevant, and the remaining led to timely management of problems.

  12. Factors Associated With Follow-Up Attendance Among Rape Victims Seen in Acute Medical Care.

    Science.gov (United States)

    Darnell, Doyanne; Peterson, Roselyn; Berliner, Lucy; Stewart, Terri; Russo, Joan; Whiteside, Lauren; Zatzick, Douglas

    2015-01-01

    Rape is associated with posttraumatic stress disorder (PTSD) and related comorbidities. Most victims do not obtain treatment for these conditions. Acute care medical settings are well positioned to link patients to services; however, difficulty engaging victims and low attendance at provided follow-up appointments is well documented. Identifying factors associated with follow-up can inform engagement and linkage strategies. Administrative, patient self-report, and provider observational data from Harborview Medical Center were combined for the analysis. Using logistic regression, we examined factors associated with follow-up health service utilization after seeking services for rape in the emergency department. Of the 521 diverse female (n = 476) and male (n = 45) rape victims, 28% attended the recommended medical/counseling follow-up appointment. In the final (adjusted) logistic regression model, having a developmental or other disability (OR = 0.40, 95% CI = 0.21-0.77), having a current mental illness (OR = 0.25, 95% CI = 0.13-0.49), and being assaulted in public (OR = 0.50, 95% CI = 0.28-0.87) were uniquely associated with reduced odds of attending the follow-up. Having a prior mental health condition (OR = 3.02, 95% CI = 1.86-4.91), a completed Sexual Assault Nurse Examiner's (SANE) examination (OR = 2.97, 95% CI = 1.84-4.81), and social support available to help cope with the assault (OR = 3.54, 95% CI = 1.76-7.11) were associated with an increased odds of attending the follow-up. Findings point to relevant characteristics ascertained at the acute care medical visit for rape that may be used to identify victims less likely to obtain posttraumatic medical and mental health services. Efforts to improve service linkage for these patients is warranted and may require alternative service delivery models that engage rape survivors and support posttraumatic recovery.

  13. Vaginismus Treatment: Clinical Trials Follow Up 241 Patients.

    Science.gov (United States)

    Pacik, Peter T; Geletta, Simon

    2017-06-01

    Vaginismus is mostly unknown among clinicians and women. Vaginismus causes women to have fear, anxiety, and pain with penetration attempts. To present a large cohort of patients based on prior published studies approved by an institutional review board and the Food and Drug Administration using a comprehensive multimodal vaginismus treatment program to treat the physical and psychologic manifestations of women with vaginismus and to record successes, failures, and untoward effects of this treatment approach. Assessment of vaginismus included a comprehensive pretreatment questionnaire, the Female Sexual Function Index (FSFI), and consultation. All patients signed a detailed informed consent. Treatment consisted of a multimodal approach including intravaginal injections of onabotulinumtoxinA (Botox) and bupivacaine, progressive dilation under conscious sedation, indwelling dilator, follow-up and support with office visits, phone calls, e-mails, dilation logs, and FSFI reports. Logs noting dilation progression, pain and anxiety scores, time to achieve intercourse, setbacks, and untoward effects. Post-treatment FSFI scores were compared with preprocedure scores. One hundred seventy-one patients (71%) reported having pain-free intercourse at a mean of 5.1 weeks (median = 2.5). Six patients (2.5%) were unable to achieve intercourse within a 1-year period after treatment and 64 patients (26.6%) were lost to follow-up. The change in the overall FSFI score measured at baseline, 3 months, 6 months, and 1 year was statistically significant at the 0.05 level. Three patients developed mild temporary stress incontinence, two patients developed a short period of temporary blurred vision, and one patient developed temporary excessive vaginal dryness. All adverse events resolved by approximately 4 months. One patient required retreatment followed by successful coitus. A multimodal program that treated the physical and psychologic aspects of vaginismus enabled women to achieve

  14. NuSTAR AND Swift Observations of the Very High State in GX 339-4: Weighing the Black Hole With X-Rays

    Science.gov (United States)

    Parker, M. L.; Tomsick, J. A.; Kennea, J. A.; Miller, J. M.; Harrison, F. A.; Barret, D.; Boggs, S. E.; Christensen, F. E.; Craig, W. W.; Fabian, A. C.; hide

    2016-01-01

    We present results from spectral fitting of the very high state of GX339-4 with Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift. We use relativistic reflection modeling to measure the spin of the black hole and inclination of the inner disk and find a spin of a = 0.95+0.08/-0.02 and inclination of 30deg +/- 1deg (statistical errors). These values agree well with previous results from reflection modeling. With the exceptional sensitivity of NuSTAR at the high-energy side of the disk spectrum, we are able to constrain multiple physical parameters simultaneously using continuum fitting. By using the constraints from reflection as input for the continuum fitting method, we invert the conventional fitting procedure to estimate the mass and distance of GX 339-4 using just the X-ray spectrum, finding a mass of 9.0+1.6/-1.2 Stellar Mass and distance of 8.4 +/- 0.9 kpc (statistical errors).

  15. Hydrotherapy after total knee arthroplasty. A follow-up study.

    Science.gov (United States)

    Giaquinto, S; Ciotola, E; Dall'Armi, V; Margutti, F

    2010-01-01

    The study evaluated the subjective functional outcome following total knee arthroplasty (TKA) in participants who underwent hydrotherapy (HT) six months after discharge from a rehabilitation unit. A total of 70 subjects, 12 of which were lost at follow-up, were randomly assigned to either a conventional gym treatment (N=30) or HT (N=28). A prospective design was performed. Participants were interviewed with Western-Ontario McMasters Universities Osteoarthritis Index (WOMAC) at admission, at discharge and six months later. Kruskal-Wallis and Wilcoxon tests were applied for statistical analysis. Both groups improved. The WOMAC subscales, namely pain, stiffness and function, were all positively affected. Statistical analysis indicates that scores on all subscales were significantly lower for the HT group. The benefits gained by the time of discharge were still found after six months. HT is recommended after TKA in a geriatric population. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

  16. Vertebral sarcoidosis: long-term follow-up with MRI

    Energy Technology Data Exchange (ETDEWEB)

    Lefere, M. [University Hospitals Gasthuisberg, Department of Radiology, Leuven (Belgium); Larbi, A.; Malghem, J.; Vande Berg, B.; Dallaudiere, B. [University Hospitals St Luc, Department of Radiology, Brussels (Belgium)

    2014-08-15

    Vertebral involvement in sarcoidosis is rare and its clinical and imaging features are non-specific. Indeed, because the lesions are hard to differentiate from metastatic disease based on imaging alone, a histological confirmation is advised. Fatty replacement is a well-known finding indicating stabilization and healing in both benign and malignant conditions. It can be used as an indicator of a favorable disease course and response to treatment. We report the case of a 43-year-old woman with multifocal vertebral sarcoidosis lesions and long-term follow-up showing progressive and gradual fatty involution on magnetic resonance imaging (MRI) during 4 years of steroid treatment with a final favorable outcome. (orig.)

  17. [Neuromuscular disease: respiratory clinical assessment and follow-up].

    Science.gov (United States)

    Martínez Carrasco, C; Villa Asensi, J R; Luna Paredes, M C; Osona Rodríguez de Torres, F B; Peña Zarza, J A; Larramona Carrera, H; Costa Colomer, J

    2014-10-01

    Patients with neuromuscular disease are an important group at risk of frequently suffering acute or chronic respiratory failure, which is their main cause of death. They require follow-up by a pediatric respiratory medicine specialist from birth or diagnosis in order to confirm the diagnosis and treat any respiratory complications within a multidisciplinary context. The ventilatory support and the cough assistance have improved the quality of life and long-term survival for many of these patients. In this paper, the authors review the pathophysiology, respiratory function evaluation, sleep disorders, and the most frequent respiratory complications in neuromuscular diseases. The various treatments used, from a respiratory medicine point of view, will be analyzed in a next paper. Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  18. Role of imaging in glaucoma diagnosis and follow-up

    Directory of Open Access Journals (Sweden)

    Vizzeri Gianmarco

    2011-12-01

    Full Text Available The purpose of the review is to provide an update on the role of imaging devices in the diagnosis and follow-up of glaucoma with an emphasis on techniques for detecting glaucomatous progression and the newer spectral domain optical coherence tomography instruments. Imaging instruments provide objective quantitative measures of the optic disc and the retinal nerve fiber layer and are increasingly utilized in clinical practice. This review will summarize the recent enhancements in confocal scanning laser ophthalmoscopy, scanning laser polarimetry, and optical coherence tomography with an emphasis on how to utilize these techniques to manage glaucoma patients and highlight the strengths and limitations of each technology. In addition, this review will briefly describe the sophisticated data analysis strategies that are now available to detect glaucomatous change overtime.

  19. Patients’ Vulnerability in Follow-up After Colorectal Cancer

    DEFF Research Database (Denmark)

    Thomsen, Thora Grothe; Hølge-Hazelton, Bibi

    2017-01-01

    and reorganizing follow-up after cancer treatment. OBJECTIVE:: The aim of this study was to identify the perspectives of fast-track colorectal cancer surgery patients on challenges experienced in the transition from being a hospitalized patient with cancer to being a cancer survivor. METHODS:: The current article...... represents phase 1 in an ongoing action research project. Data were analyzed by using the “interpretive description” method. RESULTS:: Twelve patients (6 male and 6 female patients; mean age, 72.4 years) participated in the study. The analyses show that the patients physically experienced readiness to leave......BACKGROUND:: In the transition between being a hospitalized patient with cancer and resuming “normal” life, many patients experience physical, mental, and social challenges. Scientifically, as well as politically, it is therefore recommended to undertake research with a focus on rethinking...

  20. GWASeq: targeted re-sequencing follow up to GWAS.

    Science.gov (United States)

    Salomon, Matthew P; Li, Wai Lok Sibon; Edlund, Christopher K; Morrison, John; Fortini, Barbara K; Win, Aung Ko; Conti, David V; Thomas, Duncan C; Duggan, David; Buchanan, Daniel D; Jenkins, Mark A; Hopper, John L; Gallinger, Steven; Le Marchand, Loïc; Newcomb, Polly A; Casey, Graham; Marjoram, Paul

    2016-03-03

    For the last decade the conceptual framework of the Genome-Wide Association Study (GWAS) has dominated the investigation of human disease and other complex traits. While GWAS have been successful in identifying a large number of variants associated with various phenotypes, the overall amount of heritability explained by these variants remains small. This raises the question of how best to follow up on a GWAS, localize causal variants accounting for GWAS hits, and as a consequence explain more of the so-called "missing" heritability. Advances in high throughput sequencing technologies now allow for the efficient and cost-effective collection of vast amounts of fine-scale genomic data to complement GWAS. We investigate these issues using a colon cancer dataset. After QC, our data consisted of 1993 cases, 899 controls. Using marginal tests of associations, we identify 10 variants distributed among six targeted regions that are significantly associated with colorectal cancer, with eight of the variants being novel to this study. Additionally, we perform so-called 'SNP-set' tests of association and identify two sets of variants that implicate both common and rare variants in the etiology of colorectal cancer. Here we present a large-scale targeted re-sequencing resource focusing on genomic regions implicated in colorectal cancer susceptibility previously identified in several GWAS, which aims to 1) provide fine-scale targeted sequencing data for fine-mapping and 2) provide data resources to address methodological questions regarding the design of sequencing-based follow-up studies to GWAS. Additionally, we show that this strategy successfully identifies novel variants associated with colorectal cancer susceptibility and can implicate both common and rare variants.

  1. Bariatric versus diabetes surgery after five years of follow up.

    Science.gov (United States)

    Lee, Wei-Jei; Almulaifi, Abdullah; Chong, Keong; Yao, Wei-Cheng; Tsou, Ju Juin; Ser, Kong-Han; Lee, Yi-Chih; Chen, Shu-Chun; Chen, Jung-Chien

    2016-04-01

    Bariatric surgery (BS) is totally different from diabetes surgery (DS) in the patient characters, goals of surgery, and management although similar in surgical procedure. Comparison of BS and DS with long-term data is lacking. A retrospective review of patients who received BS and patients who received DS at Min-Sheng General Hospital from 2007 to 2013 was designed. All inpatient and outpatient follow-up data were analyzed. Patients undergoing BS for the treatment of morbid obesity were compared with patients undergoing metabolic surgery for the treatment of type 2 diabetes mellitus (T2DM). Patients who received revision surgeries were excluded. The main outcome measures were: (1) operation risk; (2) weight loss; and (3) diabetes remission. Between 2007 and 2013, 2073 patients who received BS and 741 patients who received DS were recruited from both centers. DS patients were older (41.1 ± 10.9 years vs. 33.1 ± 9.3 years, p surgeries were gastric bypass procedure, whereas this procedure made up only 47.1% of BS surgeries). Although the major complication rates were similar (2.0% vs. 2.4%), the DS program had a significant higher mortality rate than the BS program (0.54% vs. 0.1%; p successful results (weight loss > 30%) and 80% of the DS patients had complete remission of their diabetes [hemoglobin A1c (HbA1c) < 6.0%]. Both the DS and the BS group had good results in up to 85% of the patients at the 5-year follow-up time point. The clinical profiles were very different between the BS and the DS programs. Both programs achieved the desired outcomes equally well, however, the DS program had a higher risk than the BS program. Copyright © 2015. Published by Elsevier Taiwan.

  2. Long-term follow-up of stentless prosthesis.

    Science.gov (United States)

    Sansone, Fabrizio; Dato, Guglielmo Mario Actis; Zingarelli, Edoardo; Ferrero, Emanuele; Prot, Sara; Ceresa, Fabrizio; Patanè, Francesco; Casabona, Riccardo

    2014-05-01

    Stentless prostheses have an interesting hemodynamic performance when compared to stented prostheses and are recommended in cases of small aortic annulus. From January 1996 to January 2004, 138 patients suffering from aortic disease, underwent aortic valve replacement. • Group A: 93 patients underwent stentless aortic valve implantation [stentless Biocor (Biocor Industria e Pesguisa Ltda, Belo Horizonte, Brazil) and stentless Sorin (Sorin Group, Saluggia, Italy)]. • Group B: 45 patients underwent stented aortic valve implantation (stented Biocor). Patients were assessed by clinical evaluation and echocardiography after a mean follow up of 124.5 ± 58.2 months. There was a significant difference in terms of time of extracorporeal circulation and aortic cross clamp. The actuarial survival at 4, 8, 12, and 15 years is 77%, 50%, 21%, and 18%, respectively. Freedom from reoperation at 4, 8, 12, and 14 years was 92%, 83%, 73%, and 63%, respectively. Freedom from all events, death, and reoperation at 4, 8, 12, and 14 years was 70%, 39%, 13%, and 8%, respectively. There is no statistical difference among the two groups in terms of actuarial survival, freedom from reoperation, and freedom from re-hospitalization for prosthesis-related causes. There was a significantly higher incidence of pacemaker implantation in Group A and the causes are not known. The rate of freedom from reoperation is high in both groups for the patients who remained alive. There was no statistical difference about prosthesis dysfunction between the two groups. The higher incidence of death in Group A cannot be explained by causes related to the prosthesis because there is no difference in terms of causes of death. Rates of reoperation did not differ between the two groups. The results obtained with stentless prostheses are encouraging even in long-term follow-up. Copyright © 2013 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  3. Magnetic resonance imaging in follow-up assessment of sciatica.

    Science.gov (United States)

    el Barzouhi, Abdelilah; Vleggeert-Lankamp, Carmen L A M; Lycklama à Nijeholt, Geert J; Van der Kallen, Bas F; van den Hout, Wilbert B; Jacobs, Wilco C H; Koes, Bart W; Peul, Wilco C

    2013-03-14

    Magnetic resonance imaging (MRI) is frequently performed during follow-up in patients with known lumbar-disk herniation and persistent symptoms of sciatica. The association between findings on MRI and clinical outcome is controversial. We studied 283 patients in a randomized trial comparing surgery and prolonged conservative care for sciatica and lumbar-disk herniation. Patients underwent MRI at baseline and after 1 year. We used a 4-point scale to assess disk herniation on MRI, ranging from 1 for "definitely present" to 4 for "definitely absent." A favorable clinical outcome was defined as complete or nearly complete disappearance of symptoms at 1 year. We compared proportions of patients with a favorable outcome among those with a definite absence of disk herniation and those with a definite, probable, or possible presence of disk herniation at 1 year. The area under the receiver-operating-characteristic (ROC) curve was used to assess the prognostic accuracy of the 4-point scores regarding a favorable or unfavorable outcome, with 1 indicating perfect discriminatory value and 0.5 or less indicating no discriminatory value. At 1 year, 84% of the patients reported having a favorable outcome. Disk herniation was visible in 35% with a favorable outcome and in 33% with an unfavorable outcome (P=0.70). A favorable outcome was reported in 85% of patients with disk herniation and 83% without disk herniation (P=0.70). MRI assessment of disk herniation did not distinguish between patients with a favorable outcome and those with an unfavorable outcome (area under ROC curve, 0.48). MRI performed at 1-year follow-up in patients who had been treated for sciatica and lumbar-disk herniation did not distinguish between those with a favorable outcome and those with an unfavorable outcome. (Funded by the Netherlands Organization for Health Research and Development and the Hoelen Foundation; Controlled Clinical Trials number, ISRCTN26872154.).

  4. One-Year Follow-Up of Patients Undergoing Transvenous Extraction of Pacemaker and Defibrillator Leads.

    Directory of Open Access Journals (Sweden)

    Maciej Kempa

    Full Text Available The number of pacemaker and ICD implantations has increased substantially in the recent years. Therefore, complications are also observed in a greater number. In many cases, transvenous extraction of the previously implanted device (pacemaker or ICD is the only solution. One may find in the literature information about the efficacy and safety of that procedure, but data concerning the results of long-term follow up are still limited.The aim of the study was to assess the one-year mortality in the cohort of patients undergoing transvenous lead extraction procedures in our centre.Records of the patients undergoing transvenous lead removal in the Department of Cardiology and Electrotherapy of the Medical University of Gdańsk were analyzed. We collected detailed information about 192 patients that had undergone the procedure from January 2003 until June 2012. Data were collected from medical and surgical records. We analyzed concomitant diseases, indications, and possible complications. Long-term follow-up data were gathered in the follow-up ambulatory records and over-the-phone interviews with patients or families. In several cases, we consulted the database of the Polish National Health Fund.During the early post-operative period 5 patients died, although none of those deaths was associated with the procedure itself. No other major complications were observed. During one-year follow-up other 5 patients died, which gave the overall one-year survival rate of 92.7%. Heart failure, renal failure and an infective indication showed significant association with increased mortality.Results of transvenous lead extraction, a relatively safe procedure, should be assessed over time extending beyond the sole perioperative period. Some complications may be delayed in their nature, and may be observed only during the long-term follow up.

  5. VizieR Online Data Catalog: UVEX sources spectroscopic follow-up (Verbeek+, 2012)

    Science.gov (United States)

    Verbeek, K.; Groot, P. J.; Scaringi, S.; Napiwotzki, R.; Spikings, B.; Ostensen, R. H.; Drew, J. E.; Steeghs, D.; Casares, J.; Corral-Santana, J. M.; Corradi, R. L. M.; Deacon, N.; Drake, J. J.; Gansicke, B. T.; Gonzalez-Solares, E.; Greimel, R.; Heber, U.; Irwin, M. J.; Knigge, C.; Nelemans, G.

    2013-04-01

    Spectroscopic follow-up was obtained by three different telescopes for a total of 132 UV-excess candidates during a number of observing runs. For 100 UV-excess candidates spectroscopic observations were obtained, during two runs in 2009 September and 2010 December, with the Intermediate dispersion Spectrograph and Imaging System (ISIS) mounted at the 4.2m William Herschel Telescope (WHT) at Roque de los Muchachos Observatory on the island of La Palma. (3 data files).

  6. Correlative Spectral Analysis of Gamma-Ray Bursts using Swift-BAT and GLAST-GBM

    International Nuclear Information System (INIS)

    Stamatikos, Michael; Sakamoto, Taka; Band, David L.

    2008-01-01

    We discuss the preliminary results of spectral analysis simulations involving anticipated correlated multi-wavelength observations of gamma-ray bursts (GRBs) using Swift's Burst Alert Telescope (BAT) and the Gamma-Ray Large Area Space Telescope's (GLAST) Burst Monitor (GLAST-GBM), resulting in joint spectral fits, including characteristic photon energy (E peak ) values, for a conservative annual estimate of ∼30 GRBs. The addition of BAT's spectral response will (i) complement in-orbit calibration efforts of GBM's detector response matrices, (ii) augment GLAST's low energy sensitivity by increasing the ∼20-100 keV effective area, (iii) facilitate ground-based follow-up efforts of GLAST GRBs by increasing GBM's source localization precision, and (iv) help identify a subset of non-triggered GRBs discovered via off-line GBM data analysis. Such multi-wavelength correlative analyses, which have been demonstrated by successful joint-spectral fits of Swift-BAT GRBs with other higher energy detectors such as Konus-WIND and Suzaku-WAM, would enable the study of broad-band spectral and temporal evolution of prompt GRB emission over three energy decades, thus potentially increasing science return without placing additional demands upon mission resources throughout their contemporaneous orbital tenure over the next decade.

  7. SWIFT J2058.4+0516: DISCOVERY OF A POSSIBLE SECOND RELATIVISTIC TIDAL DISRUPTION FLARE?

    Energy Technology Data Exchange (ETDEWEB)

    Bradley Cenko, S.; Butler, Nathaniel R.; Bloom, Joshua S.; Filippenko, Alexei V.; Silverman, Jeffrey M. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Krimm, Hans A. [CRESST and NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Horesh, Assaf; Quimby, Robert M.; Kulkarni, S. R.; Ofek, Eran O. [Division of Physics, Mathematics, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Rau, Arne; Greiner, Jochen; Olivares E, Felipe; Schady, Patricia [Max-Planck Institute for Extraterrestrial Physics, Giessenbachstrasse 1, Garching 85748 (Germany); Frail, Dale A. [National Radio Astronomy Observatory, P.O. Box 0, Socorro, NM 87801 (United States); Kennea, Jamie A. [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States); Levan, Andrew J. [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom); Holland, Stephen T. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Gal-Yam, Avishay [Department of Particle Physics and Astrophysics, Faculty of Physics, The Weizmann Institute of Science, Rehovot 76100 (Israel); Tanvir, Nial R., E-mail: cenko@astro.berkeley.edu [Department of Physics and Astronomy, University of Leicester, University Road, Leicester LE1 7RH (United Kingdom); and others

    2012-07-01

    We report the discovery by the Swift hard X-ray monitor of the transient source Swift J2058.4+0516 (Sw J2058+05). Our multi-wavelength follow-up campaign uncovered a long-lived (duration {approx}> months), luminous X-ray (L{sub X,iso} Almost-Equal-To 3 Multiplication-Sign 10{sup 47} erg s{sup -1}) and radio ({nu}L{sub {nu},iso} Almost-Equal-To 10{sup 42} erg s{sup -1}) counterpart. The associated optical emission, however, from which we measure a redshift of 1.1853, is relatively faint, and this is not due to a large amount of dust extinction in the host galaxy. Based on numerous similarities with the recently discovered GRB 110328A/Swift J164449.3+573451 (Sw J1644+57), we suggest that Sw J2058+05 may be the second member of a new class of relativistic outbursts resulting from the tidal disruption of a star by a supermassive black hole. If so, the relative rarity of these sources (compared with the expected rate of tidal disruptions) implies that either these outflows are extremely narrowly collimated ({theta} < 1 Degree-Sign ) or only a small fraction of tidal disruptions generate relativistic ejecta. Analogous to the case of long-duration gamma-ray bursts and core-collapse supernovae, we speculate that rapid spin of the black hole may be a necessary condition to generate the relativistic component. Alternatively, if powered by gas accretion (i.e., an active galactic nucleus (AGN)), Sw J2058+05 would seem to represent a new mode of variability in these sources, as the observed properties appear largely inconsistent with known classes of AGNs capable of generating relativistic jets (blazars, narrow-line Seyfert 1 galaxies).

  8. Follow-up studies on children and adolescents with Graves' disease after 131I treatment

    International Nuclear Information System (INIS)

    Chen Danyun; Chen Tanghua

    2006-01-01

    Objective: To observe relative long-term radioactive therapy effects, clinical follow-up after 131 I treatment was conducted in children and adolescent patients with Graves' disease (GD). Methods: In 161 GD patients, aged from 8 to 17 years, m I was given at a dosage of 1.85 to 3.70 MBq per gram of thyroid tissue and a maximum dose ranging from 74 to 1221 MBq per patient. The patients were then followed up for 24 to 104 months [averagely (62±22) months]. Results: After 131 I treatment, ninety-eight (60.87%) patients were found to be euthyroid. Nine (5.59%) patients remained hyperthyroid and another three (1.86%) had recurrence of hyperthyroidism. Thirty-seven (22.98%) patients turned to be hypothyroid. Fourteen patients lost in follow-up. During the follow-up period, no thyroid cancer or genetic abnormalities were ever found in the group of patients, neither in their offsprings. Conclusion: 131 I may well be considered as an effective and safe method for treating children and adolescents with GD. . (authors)

  9. Diagnosis, surgical treatment and follow-up of thyroid cancers

    International Nuclear Information System (INIS)

    Pacini, F.; Pinchera, A.; Vorontsova, T.; Demidchik, E.P.; Delange, F.; Reiners, C.; Schlumberger, M.

    1996-01-01

    This paper reports the activities and the results of the research carried out by the Centers participating to the JSP4 project, within the framework of the EU program on the consequences of the Chernobyl disaster. The project was aimed to develop and to control the application of basic principles for the diagnosis, treatment and follow-up of thyroid carcinoma, with special attention to the peculiar requirement of children and adolescents. To this purpose, training in Western European Centers was offered to a number of scientists from Belarus, Ukraine and Russia. Several official meetings were organized to share views and to discuss the progress of the project. A basic protocol for the diagnosis, treatment and follow-up of thyroid carcinoma has been developed and approved by all participating Centers. Hopefully, it will be applied to the new cases and to those already under monitoring. A large part of the protocol is dedicated to the post-surgical treatment with thyroid hormones for the suppression of TSH and with calcitriol for the management of surgical hypoparathyroidism. A detailed protocol to asses iodine deficiency and, eventually, to introduce a program of iodine supplementation has been proposed. The collection of control cases of childhood thyroid carcinoma in non-radiation exposed European countries has been initiated in Italy, France and Germany. This data will be used as control for the post-Chernobyl childhood thyroid carcinomas. Here is reported a preliminary comparison of the clinical and epidemiological features of almost all (n=368) radiation-exposed Belarus children who developed thyroid carcinoma (age at diagnosis < 16 years), with respect to 90 children of the same age group, who, in the past 20 years, have received treatment for thyroid carcinoma in two centers in Italy (Pisa and Rome). Finally, by molecular biology, genetic mutations of the RET proto-oncogene have been found in several samples of thyroid carcinomas provided by the Belarus

  10. The LCO Follow-up and Characterization Network and AgentNEO Citizen Science Project

    Science.gov (United States)

    Lister, Tim; Greenstreet, Sarah; Gomez, Edward; Christensen, Eric J.; Larson, Stephen M.

    2017-10-01

    The LCO NEO Follow-up Network is using the telescopes of the Las Cumbres Observatory (LCO) and a web-based target selection, scheduling and data reduction system to confirm NEO candidates and characterize radar-targeted known NEOs. Starting in July 2014, the LCO NEO Follow-up Network has observed over 4,500 targets and reported more than 25,000 astrometric and photometric measurements to the Minor Planet Center.The LCO NEO Follow-up Network's main aims are to perform confirming follow-up of the large number of NEO candidates and to perform characterization measurements of radar targets to obtain light curves and rotation rates. The NEO candidates come from the NEO surveys such as Catalina, PanSTARRS, ATLAS, NEOWISE and others. In particular, we are targeting objects in the Southern Hemisphere, where the LCO NEO Follow-up Network is the largest resource for NEO observations.The first phase of the LCO Network comprises nine 1-meter and seven 0.4-meter telescopes at site at McDonald Observatory (Texas), Cerro Tololo (Chile), SAAO (South Africa) and Siding Spring Observatory (Australia). The network has been fully operational since 2014 May, and observations are being executed remotely and robotically. Additional 0.4-meter telescopes will be deployed in 2017 and 2x1-meter telescopes for a site at Ali Observatory, Tibet are planned for 2018-2019.We have developed web-based software called NEOexchange which automatically downloads and aggregates NEO candidates from the Minor Planet Center's NEO Confirmation Page, the Arecibo and Goldstone radar target lists and the NASA lists. NEOexchange allows the planning and scheduling of observations on the LCO Telescope Network and the tracking of the resulting blocks and generated data. We have extended the NEOexchange software to include automated scheduling and moving object detection, with the results presented to the user via the website.We will present results from the LCO NEO Follow-up Network and from the development of the

  11. Update of the Polar SWIFT model for polar stratospheric ozone loss (Polar SWIFT version 2)

    Science.gov (United States)

    Wohltmann, Ingo; Lehmann, Ralph; Rex, Markus

    2017-07-01

    The Polar SWIFT model is a fast scheme for calculating the chemistry of stratospheric ozone depletion in polar winter. It is intended for use in global climate models (GCMs) and Earth system models (ESMs) to enable the simulation of mutual interactions between the ozone layer and climate. To date, climate models often use prescribed ozone fields, since a full stratospheric chemistry scheme is computationally very expensive. Polar SWIFT is based on a set of coupled differential equations, which simulate the polar vortex-averaged mixing ratios of the key species involved in polar ozone depletion on a given vertical level. These species are O3, chemically active chlorine (ClOx), HCl, ClONO2 and HNO3. The only external input parameters that drive the model are the fraction of the polar vortex in sunlight and the fraction of the polar vortex below the temperatures necessary for the formation of polar stratospheric clouds. Here, we present an update of the Polar SWIFT model introducing several improvements over the original model formulation. In particular, the model is now trained on vortex-averaged reaction rates of the ATLAS Chemistry and Transport Model, which enables a detailed look at individual processes and an independent validation of the different parameterizations contained in the differential equations. The training of the original Polar SWIFT model was based on fitting complete model runs to satellite observations and did not allow for this. A revised formulation of the system of differential equations is developed, which closely fits vortex-averaged reaction rates from ATLAS that represent the main chemical processes influencing ozone. In addition, a parameterization for the HNO3 change by denitrification is included. The rates of change of the concentrations of the chemical species of the Polar SWIFT model are purely chemical rates of change in the new version, whereas in the original Polar SWIFT model, they included a transport effect caused by the

  12. Long term follow up in hemodialysis patients with parathyroidectomy

    International Nuclear Information System (INIS)

    Alvarez, A.; Petraglia, A.; Caorsi, H.; Mazzuchi, N.; Olaizola, I.; Acuna, G.; Fajardo, L.; Ambrosoni, P.; Morelli, R.

    1998-01-01

    A retrospective study was performed in 41 patients, in chronic hemodialysis with severe hyperparathyroidism (HPT), who underwent surgery during time period from 1985 to 1997. 22 females, 19 males, aged 50 and 14 years, with PTHI 1345 and 604 pg/ml were followed up 32 and 22 months. Three surgical methods we evaluated: group I) total para thyroidectomy(PTX) with Implants(n=24); group II) subtotal PTX(n=14) and group III) total PTX(n=3). It considered recurrence of HPT when PTH levels were higher than upper range of normal, after 6 months post surgery. persistence was defined when there was no standardization of PTH levels. In group I, 9 patients had normal parathyroid function, 7 had persistent hypoparathyroidism and had hyperparathyroidism (7 recurrences). Group II patients had parathyroid over function in 5 cases (4 persistence s), 5 were normal and 4 hypoparathyroidism. All patients of the third group had hypoparathyroidism. Long term normalization of parathyroid gland activity was achieved in one third of troduccion patients (34,1%) whereas 34,1% permanent hypoparathyroidism and 31,8% hyperparathyroidism. It found no differences in recurrence and histological subtype of parathyroid gland in the different groups. In conclusion, similar long term clinical results were obtained with the different groups. The surgical ideal treatment is controversial. We think that in the long run, the evolution of parathyroid status is mostly influenced by the persistence of uremic state rather than the type of surgery performed [es

  13. Spectroscopic follow-up of the Hercules-Aquila Cloud

    Science.gov (United States)

    Simion, Iulia T.; Belokurov, Vasily; Koposov, Sergey E.; Sheffield, Allyson; Johnston, Kathryn V.

    2018-05-01

    We designed a follow-up program to find the spectroscopic properties of the Hercules-Aquila Cloud (HAC) and test scenarios for its formation. We measured the radial velocities (RVs) of 45 RR Lyrae in the southern portion of the HAC using the facilities at the MDM observatory, producing the first large sample of velocities in the HAC. We found a double-peaked distribution in RVs, skewed slightly to negative velocities. We compared both the morphology of HAC projected on to the plane of the sky and the distribution of velocities in this structure outlined by RR Lyrae and other tracer populations at different distances to N-body simulations. We found that the behaviour is characteristic of an old, well-mixed accretion event with small apo-galactic radius. We cannot yet rule out other formation mechanisms for the HAC. However, if our interpretation is correct, HAC represents just a small portion of a much larger debris structure spread throughout the inner Galaxy whose distinct kinematic structure should be apparent in RV studies along many lines of sight.

  14. Bradykinesia in Huntington's disease. A prospective, follow-up study.

    Science.gov (United States)

    García Ruiz, Pedro J; Hernández, Jaime; Cantarero, Susana; Bartolomé, Manuel; Sánchez Bernardos, Vicenta; García de Yébenez, Justo

    2002-04-01

    Bradykinesia is a frequent finding in Huntington's disease (HD), but some aspects are presently unknown; including the natural evolution of bradykinesia over time and the correlation between bradykinesia and functional capacity. We studied the motor performance of 20 genetically confirmed patients with HD (age: 40+/-10.8 years; age at onset 33.6+/-11 years; total functional capacity (TFC): 9.57+/-3; UHDRS total motor scale: 31.4+/-13, triplet length (CAG)n: 46.7+/-4 triplets). These patients were studied in baseline conditions and after 18.7+/-6 months of follow-up. In addition, HD patients were compared with 20 age-matched normal controls. Motor study included the four CAPIT timed tests commonly used for Parkinson's disease: pronation-supination (PS), finger dexterity (FD), movement between two points (MTP) and walking test (WT). HD patients were significantly slower than controls in all motor tasks. A significant deterioration occurred over time in three of the four motor tasks (especially FD and WT). A significant correlation between timed tests and TFC score was found (for MTP, r: -0.845; p < 0,0001). In addition a significant correlation between timed tests and the UHDRDS total motor scale was also found (for MTP, r: 0.864; p < 0.0001). In conclusion, simple timed motor tests can detect a deterioration of motor activity over time in HD. Timed tests might be useful to follow the natural evolution of HD and to assess the efficacy of new therapies.

  15. [Diagnosis, treatment, and follow-up of cesarean scar pregnancy].

    Science.gov (United States)

    Nguyen-Xuan, H-T; Lousquy, R; Barranger, E

    2014-01-01

    Cesarean scar pregnancy is a rare entity. This situation may induce uterine rupture and/or a massive life-threatening hemorrhage. The standard treatment is laparotomy surgery, but in situ injections to replace invasive surgery. The objective of this study was to focus on the diagnosis, optimal management and long-term follow-up of the patients. Data from 6 patients with diagnosis of cesarean scar pregnancy between 2007 and 2013 at Lariboisière hospital were retrospectively collected. Endovaginal ultrasound succeeded to diagnose all cases. Four patients were treated with in situ injection of methotrexate performing a vaginal way (n=2) or laparoscopy (n=2) and two others using systemic injection. One patient was complicated by hemorrhagic shock requiring iterative embolizations. Three patients achieved a new pregnancy, with one recurrent scar pregnancy complicated by massive hemorrhage. Diagnosis and treatment of cesarean scar pregnancies must be done precociously because of high hemorrhage risks. Endovaginal ultrasound is the gold standard exam. Treatment is non-consensual, but methotrexate in situ injection is effective and safer. Monitoring the decrease of HCG levels and ultrasonography supervision of gestational sac size and its vascularization must be performed. Due to the risk of recurrence, any subsequent pregnancy shows a high risk of complications. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  16. Thyroid carcinoma: A follow-up study of 11 years

    International Nuclear Information System (INIS)

    Ritzl, F.; Siebers, G.; Neumann, C.; Ritzl, E.K.

    1987-01-01

    During a follow-up of 11 years of thyroid carcinoma 136 patients were repeatedly examined. 43% papillary, 43% follicular, 11% anaplastic and 2% medullary carcinomas was found. The incidence of these types of carcinoma differed considerably; the frequency peak of papillary carcinomas was reached in 45-year-old humans, that of the follicular carcinomas in people aged 60, that of the anaplastic carcinomas in 70-year-old humans. 84% of the patients was female. Classification in pTNM-system: 8% in pT1, 27% in pT2, 12% in pT3 and 49% in pT4. Local and distant metastases were found at a low rate equally in pT1, pT2 and pT3; 26% of patients in pT4 had local metastases and 18% had distant ones in addition. There were 6 patients with metastases of a differentiated adenocarcinoma accumulating no 131-iodine and with no thyroglobulin in serum. 29% of patients had after thyroidectomy an unilateral paresis of the nervus recurrens and 4% a bilateral one. 26% of patients had a permanent hypoparathyroidism after thyroidectomy. (orig.)

  17. Thyroid carcinoma: A follow-up study of 11 years

    Energy Technology Data Exchange (ETDEWEB)

    Ritzl, F.; Siebers, G.; Neumann, C.; Ritzl, E.K.

    1987-09-01

    During a follow-up of 11 years of thyroid carcinoma 136 patients were repeatedly examined. 43% papillary, 43% follicular, 11% anaplastic and 2% medullary carcinomas was found. The incidence of these types of carcinoma differed considerably; the frequency peak of papillary carcinomas was reached in 45-year-old humans, that of the follicular carcinomas in people aged 60, that of the anaplastic carcinomas in 70-year-old humans. 84% of the patients was female. Classification in pTNM-system: 8% in pT1, 27% in pT2, 12% in pT3 and 49% in pT4. Local and distant metastases were found at a low rate equally in pT1, pT2 and pT3; 26% of patients in pT4 had local metastases and 18% had distant ones in addition. There were 6 patients with metastases of a differentiated adenocarcinoma accumulating no 131-iodine and with no thyroglobulin in serum. 29% of patients had after thyroidectomy an unilateral paresis of the nervus recurrens and 4% a bilateral one. 26% of patients had a permanent hypoparathyroidism after thyroidectomy.

  18. SDSS-III MARVELS Planet Candidate RV Follow-up

    Science.gov (United States)

    Ge, Jian; Thomas, Neil; Ma, Bo; Li, Rui; SIthajan, Sirinrat

    2014-02-01

    Planetary systems, discovered by the radial velocity (RV) surveys, reveal strong correlations between the planet frequency and stellar properties, such as metallicity and mass, and a greater diversity in planets than found in the solar system. However, due to the sample sizes of extant surveys (~100 to a few hundreds of stars) and their heterogeneity, many key questions remained to be addressed: Do metal poor stars obey the same trends for planet occurrence as metal rich stars? What is the distribution of giant planets around intermediate- mass stars and binaries? Is the ``planet desert'' within 0.6 AU in the planet orbital distribution of intermediate-mass stars real? The MARVELS survey has produced the largest homogeneous RV measurements of 3300 V=7.6-12 FGK stars. The latest data pipeline effort at UF has been able to remove long term systematic errors suffered in the earlier data pipeline. 18 high confident giant planet candidates have been identified among newly processed data. We propose to follow up these giant planet candidates with the KPNO EXPERT instrument to confirm the detection and also characterize their orbits. The confirmed planets will be used to measure occurrence rates, distributions and multiplicity of giants planets around F,G,K stars with a broad range of mass (~0.6-2.5 M_⊙) and metallicity ([Fe/H]~-1.5-0.5). The well defined MARVELS survey cadence allows robust determinations of completeness limits for rigorously testing giant planet formation theories and constraining models.

  19. Treatment and follow-up of obesity in adolescent girls.

    Science.gov (United States)

    Hoerr, S L; Nelson, R A; Essex-Sorlie, D

    1988-01-01

    An intervention program was conducted for 12 postmenarche, 12-15-year-old obese girls. Weight Winners, a multicomponent and multidisciplinary after-school intervention program, was developed in which behavior modification, aerobic exercise, and modeling appropriate behaviors for weight control were emphasized. Evaluation made before and immediately after the intervention and at a nine-month follow-up suggested that the after-school treatment program was successful in: 1) reducing the rate of gain and decreasing body weight by 11% while maintaining lean tissue and resting energy expenditure (REE), and 2) improving eating and exercise behaviors. Significant changes in eating behaviors (p less than 0.05) were: more low-calorie, nutritionally dense foods were consumed; the frequency and amount eaten decreased; and the speed of eating slowed. Implementing a fee contingent on attendance and on record keeping appeared to reduce attrition. Subjects cited the Weight Winners program, aerobic exercise, changes in eating behaviors, group and family support, and encouragement and praise from the group leaders as important contributions to their success in weight control. Barriers to change were reported by participants as boredom, hunger, lack of family and peer support, and having food in sight. An increase in lean tissue was associated with both improved self-esteem (p less than 0.05) and improved self-control (p less than 0.05). Subjects who had been obese the longest were the most responsive to hunger cues (p less than 0.05).

  20. Patients’ follow-up using biomechanical analysis of rehabilitation exercises

    Directory of Open Access Journals (Sweden)

    Bruno Bonnechère

    2017-03-01

    Full Text Available Thanks to the evolution of game controllers video games are becoming more and more popular in physical rehabilitation. The integration of serious games in rehabilitation has been tested for various pathologies. Parallel to this clinical research, a lot of studies have been done in order to validate the use of these game controllers for simple biomechanical evaluation. Currently, it is thus possible to record the motions performed by the patients during serious gaming exercises for later analysis. Therefore, data collected during the exercises could be used for monitoring the evolution of the patients during long term rehabilitation. Before using the parameters extracted from the games to assess patients’ evolution two important aspects must be verified: the reproducibility of measurement and a possible effect of learning of the task to be performed. Ten healthy adults played 9 sessions of specific games developed for rehabilitation over a 3-weeks period. Nineteen healthy children played 2 sessions to study the influence of age. Different parameters were extracted from the games: time, range of motion, reaching area. Results of this study indicates that it is possible to follow the evolution of the patients during the rehabilitation process. The majority of the learning effect occurred during the very first session. Therefore, in order to allow proper regular monitoring, the results of this first session should not be included in the follow-up of the patient.

  1. Spectroscopic Follow-Up of the Hercules Aquila Cloud

    Science.gov (United States)

    Simion, Iulia T.; Belokurov, Vasily; Koposov, Sergey E.; Sheffield, Allyson; Johnston, Kathryn V.

    2018-02-01

    We designed a follow-up program to find the spectroscopic properties of the Hercules-Aquila Cloud (HAC) and test scenarios for its formation. We measured the radial velocities (RVs) of 45 RR Lyrae in the southern portion of the HAC using the facilities at the MDM observatory, producing the first large sample of velocities in the HAC. We found a double-peaked distribution in RVs, skewed slightly to negative velocities. We compared both the morphology of HAC projected onto the plane of the sky and the distribution of velocities in this structure outlined by RR Lyrae and other tracer populations at different distances to N-body simulations. We found that the behaviour is characteristic of an old, well-mixed accretion event with small apo-galactic radius. We cannot yet rule out other formation mechanisms for the HAC. However, if our interpretation is correct, HAC represents just a small portion of a much larger debris structure spread throughout the inner Galaxy whose distinct kinematic structure should be apparent in RV studies along many lines of sight.

  2. Follow-up measles campaign in the Dominican Republic.

    Science.gov (United States)

    1998-12-01

    The Dominican Republic conducted a national follow-up measles vaccination campaign 6 weeks after sustaining heavy damage from Hurricane Georges, on November 6-12, targeting 830,517 children aged 9 months to 5 years in 29 provinces and the capital city. This campaign was the first mass vaccination effort in the country, following the beginning of the decentralized delivery of health services. Priority was given to vaccinating against diphtheria, whooping cough, and tetanus, especially in refugee camps. More than 500,000 vaccines were given to different age groups, with almost 100,000 of those immunized under 5 years old. Children aged 9 months to 5 years were targeted for immunization regardless of their vaccination status. At the same time, children aged 2 months through 2 years were immunized against poliomyelitis. Vaccination activities were continued until the entire target population was reached and no important side effects have thus far been reported. The government of Mexico donated 300,000 doses of measles vaccine, while other vaccines for the campaign were acquired through the PAHO Revolving Fund for Vaccine Procurement. The decentralized implementation of this campaign allowed the population to actively participate and the resulting high vaccination coverage rates.

  3. Measles vaccine: a 27-year follow-up.

    LENUS (Irish Health Repository)

    Ramsay, M E

    1994-04-01

    In 1964, the Medical Research Council undertook a trial of measles vaccine in over 36,000 United Kingdom children; 9577 of whom received live vaccine, 10,625 received inactivated followed by live vaccines, and 16,328 acted as unvaccinated controls. Participants in this study have been followed to determine the long term protection from measles vaccine and follow-up data were available on 4194, 4638 and 274 respectively. During the 5-year period 1986-90, the protective efficacy of live measles vaccine has remained high at 87%, but the 95% confidence interval was wide (-43 to 99%) due to the small numbers of cases. Between 1976 and 1990, however, the overall efficacy of the live vaccine was 92% (95% confidence interval 86 to 95%) and there was no evidence of a decline in efficacy (P = 0.13) over the 15-year period. This study suggests that the protection from live measles vaccine persists for up to 27 years after vaccination, and that no change in the current United Kingdom measles immunization policy should be made on the grounds of waning immunity.

  4. Primary testicular plasmocytoma: A five year follow-up

    Directory of Open Access Journals (Sweden)

    Milton Ghirelli Filho

    2013-01-01

    Full Text Available The testicular plasmocytoma represents only 5% of the non-germinative cell testicular tumors, and accounts for only 2% of all plasma cell neoplasms. Approximately, 50 cases of testicular plasmocytoma have been reported in medical literature; however, only 9 of these are isolated tumors without previous history or progression to multiple myeloma. A 47-year-old patient, presenting progressive and painless growth of the right testicle in the last four years, underwent surgical treatment in another hospital two years ago, to correct a hydrocele in the same testicle with no improvement at all. Sonography showed a tumor with the following measurements for the right testicle: 84 × 59 × 80 mm. The tumor marker values were all normal. An abdominal computed tomography found no evidence of retroperitoneal lymph nodes invasion. The patient underwent a right radical orchiectomy. Pathologic analysis revealed a malignant neoplasia described as a plasmocytoma (solitary myeloma that produces immunoglobulin′s kappa light chain. After five years of follow-up, there were no signs of metastasis or local recurrence in the exams. Case report and review of literature have been presented here.

  5. Diagnosis, Treatment, and Follow-Up of Borderline Ovarian Tumors

    Science.gov (United States)

    Zikan, Michal; Dundr, Pavel; Cibula, David

    2012-01-01

    Borderline ovarian tumors represent a heterogeneous group of noninvasive tumors of uncertain malignant potential with characteristic histology. They occur in younger women, are present at an early stage, and have a favorable prognosis, but symptomatic recurrence and death may be found as long as 20 years after therapy in some patients. The molecular changes in borderline ovarian tumors indicate linkage of this disease to type I ovarian tumors (low-grade ovarian carcinomas). The pathological stage of disease and subclassification of extraovarian disease into invasive and noninvasive implants, together with the presence of postoperative macroscopic residual disease, appear to be the major predictor of recurrence and survival. However, it should be emphasized that the most important negative prognostic factor for recurrence is just the use of conservative surgery, but without any impact on patient survival because most recurrent diseases are of the borderline type—easily curable and with an excellent prognosis. Borderline tumors are difficult masses to correctly preoperatively diagnose using imaging methods because their macroscopic features may overlap with invasive and benign ovarian tumors. Over the past several decades, surgical therapy has shifted from a radical approach to more conservative treatment; however, oncologic safety must always be balanced. Follow-up is essential using routine ultrasound imaging, with special attention paid to the remaining ovary in conservatively treated patients. Current literature on this topic leads to a number of controversies that will be discussed thoroughly in this article, with the aim to provide recommendations for the clinical management of these patients. PMID:23024155

  6. Swift UVOT Detection of GRB 050318

    Science.gov (United States)

    Still, M.; Roming, P. W. A.; Mason, K. O.; Blustin, A.; Boyd, P.; Breeveld, A.; Brown, P.; De Pasquale, M.; Gronwall, C.; Holland, S. T.; Hunsberger, S.; Ivanushkina, M.; James, C.; Landsman, W.; McGowan, K.; Morgan, A.; Poole, T.; Rosen, S.; Schady, P.; Zhang, B.; Krimm, H.; Sakamoto, T.; Giommi, P.; Goad, M. R.; Mangano, V.; Page, K.; Perri, M.; Burrows, D. N.; Gehrels, N.; Nousek, J.

    2005-12-01

    We present observations of GRB 050318 by the Ultraviolet/Optical Telescope (UVOT) on board the Swift observatory. The data are the first detections of a gamma-ray burst (GRB) afterglow decay by the UVOT instrument, launched specifically to open a new window on these transient sources. We showcase UVOT's ability to provide multicolor photometry and the advantages of combining UVOT data with simultaneous and contemporaneous observations from the high-energy detectors on the Swift spacecraft. Multiple filters covering 1800-6000 Å reveal a red source with a spectral slope steeper than the simultaneous X-ray continuum. Spectral fits indicate that the UVOT colors are consistent with dust extinction by systems at z=1.2037 and 1.4436, redshifts where absorption systems have been preidentified. However, the data can be most easily reproduced with models containing a foreground system of neutral gas redshifted by z=2.8+/-0.3. For both of the above scenarios, spectral and decay slopes are, for the most part, consistent with fireball expansion into a uniform medium, provided a cooling break occurs between the energy ranges of the UVOT and Swift's X-ray instrumentation.

  7. Metabolically healthy obesity and depressive symptoms: 16-year follow-up of the Gazel cohort study.

    Science.gov (United States)

    Hinnouho, Guy-Marino; Singh-Manoux, Archana; Gueguen, Alice; Matta, Joane; Lemogne, Cedric; Goldberg, Marcel; Zins, Marie; Czernichow, Sébastien

    2017-01-01

    The health correlates of the metabolically healthy obese (MHO) phenotype, particularly in relation to depressive symptoms remains unclear. Accordingly, we examined the risk of depressive symptoms in this phenotype using a 16-year follow-up prospective study. A sample of 14 475 participants (75% men), aged 44-59 years in 1996, was drawn from the Gazel cohort. Obesity was defined as body mass index (BMI) ≥ 30 kg/m2 and metabolic health as having none of the self-reported following cardiovascular risk factors: hypertension, type 2 diabetes and dyslipidemia. Depressive symptoms were assessed by the Center for Epidemiologic Studies Depression (CES-D) scale in 1996, 1999, 2002, 2005, 2008 and 2012. Generalized Estimating Equations (GEE) were used to estimate the risk of depressive symptoms during a follow-up of 16 years. In multivariate analyses, metabolically unhealthy normal weight [Odds Ratio (OR) = 1.37; 95% Confidence Interval (CI): 1.25-1.51], overweight [1.44 (1.31-1.59)] and obese [1.30 (1.10-1.54)] but not MHO participants [1.04 (0.81-1.32)] had higher risk of depressive symptoms at the start of follow-up compared to metabolically healthy normal weight individuals. Depressive symptoms decreased over time in metabolically healthy normal weight individuals [0.52 (0.50-0.55)], this decrease was less marked only in metabolically unhealthy obese participants [1.22 (1.07-1.40)]. Compared to MHO participants, metabolically unhealthy obese individuals were at increased risk of depression at the start of follow-up, but with a similar reduction of this risk over time. Poor metabolic health, irrespective of BMI was associated with greater depressive symptoms at the start of follow-up, whereas a poorer course of depressive symptoms over time was observed only in those with both obesity and poor metabolic health.

  8. Electrochemical sensors in breast cancer diagnostics and follow-up

    Directory of Open Access Journals (Sweden)

    Raquel Marques

    2015-12-01

    electrodes (SPCEs were used as the transducers. These SPCEs (working volume: ~40 μL are widely employed in the construction of electrochemical (biosensors because of several reasons: simplicity and low cost, versatility of design, small dimensions and possibility of incorporation in portable systems, as well as adequate electroanalytical characteristics. These SPCEs were modified with gold nanoparticles (nAu through the electrochemical deposition of ionic gold from a solution. The developed sensors were applied to the analysis of the selected biomarkers in spiked human serum samples.Besides these immunosensors, a molecularly imprinted polymer (MIP sensor was developed for the analysis of HER2-ECD. In this case a gold electrode was used as the transducer. The MIP was formed by surface imprinting and electrochemical impedance spectroscopy and voltammetry were used for detection purposes.Results: For the immunoassays the following parameters were optimized: capture and detection antibody concentration, surface blocking, reaction mixtures and incubation times. The best limits of detection obtained were below the established cut-off values (25 U/mL and 15 ng/mL for CA15-3 and HER2-ECD, respectively. For the MIP sensor the most adequate polymer was chosen and the electropolymerization, template removal, and incubation conditions were optimized. The lowest HER2-ECD concentration that was analyzed was 50 µg/mL.Conclusion: The obtained results indicate that the developed sensors could be promising tools in breast cancer diagnostics and follow-up. However, further studies should be conducted using patients' samples and the results of these assays should be validated with the established analysis procedures for these cancer biomarkers.-----------------------------------------Cite this article as:  Marques R, Pacheco J, Rama EC, Viswanathan S, Nouws H, Delerue-Matos C. Electrochemical sensors in breast cancer diagnostics and follow-up. Int J Cancer Ther Oncol 2015; 3(4:34012.[This

  9. Parenchymal neurocysticercosis: follow-up and staging by MRI

    Energy Technology Data Exchange (ETDEWEB)

    Dumas, J.L. [Dept. of Radiology, Hopital Avicenne, Bobigny (France)]|[Inst. of Tropical Neurology, Faculty of Medicine, Limoges (France); Visy, J.M. [Dept. of Neurology, Hopital Lariboisiere, Paris (France); Belin, C. [Dept. of Neurology, Hopital Avicenne, Bobigny (France); Gaston, A. [Dept. of Neuroradiology, Hopital Henri-Mondor, Creteil (France); Goldlust, D. [Dept. of Radiology, Hopital Avicenne, Bobigny (France); Dumas, M. [Inst. of Tropical Neurology, Faculty of Medicine, Limoges (France)

    1997-01-01

    We describe the evolution of parenchymal cerebral cysticerci on MRI, to assess signs of early cyst degeneration. We studied 15 lesions in four treated and one untreated patient. MRI was performed before therapy and repeated in the 1st month after each course of anticysticercus drugs, every 4 months during the 1st year and then annually; the follow-up period was 8-48 months. Lesions were classified according to changes in four features: cyst content and capsule signal, gadolinium enhancement and oedema signal. We were able to recognise each of the pathological phases; five MRI stages were identified. Stage 1 showed oedema and/or nodular gadolinium enhancement in the tissue invasion phase; stage 2 was cerebrospinal fluid-like signal within a cyst in the vesicular phase; stage 3 showed a thick capsule with an impure liquid content signal and surrounding oedema, in the cystic phase; stage 4 showed the disappearance of the cyst fluid content signal in the degenerative phase; stage 5 showed a calcified lesion in the residual phase. Stage 1 lesions disappeared after therapy; the other progressed from one stage to another. Stage 4 indicated the end of viability of the parasite and determined the point after which treatment was useless. On T2-weighted images changes in the cyst content differed according to the history of the lesion; nodular low intensity followed the natural degeneration of the parasite and a mixed fluid signal with punctate low signal seemed to represent the specific result of therapy. MRI staging can help in the evaluation of indications for treatment and facilitate clinical therapeutic trials. (orig.). With 4 figs., 1 tab.

  10. Clinical features and follow-up of congenital syphilis.

    Science.gov (United States)

    Lago, Eleonor G; Vaccari, Alessandra; Fiori, Renato M

    2013-02-01

    The aim of this study was to investigate clinical features and outcomes of children treated for congenital syphilis (CS). Infants born alive in the public sector of São Lucas Hospital, Porto Alegre, Brazil, 1997 to 2004, whose mothers had syphilis and neonates with CS born in other facilities and admitted during this period were included. Follow-up was performed from birth up to 5 years. Among 24,920 live births, 379 (1.5%) met the criteria for CS. A further 19 infants born in other hospitals were included, for a total of 398 with CS. We compared infants with CS with 120 infants whose mothers received adequate treatment of syphilis before delivery (total sample, 518 infants). Congenital syphilis was associated with delivery before 34 weeks, low birth weight, and small for gestational age. During the study period, 37 stillbirths with CS were detected. Result from the serum venereal disease research laboratory test was negative at birth in 17.5% of the neonates with CS, and in 4 infants, it became positive after the second day. Thirty percent of the infants with CS were reevaluated between 8 and 60 months, and most had a good outcome when managed according to standard guidelines. Sixteen infants (13.3%) had sequelae. Of these, 8 were symptomatic in the neonatal period, and 13 (81%) of 16 had laboratory/x-ray findings. All asymptomatic and 78% of symptomatic infants had nonreactive fluorescent treponemal antibody absorption test after 12 months of age. Congenital syphilis remains an impacting disease that causes fetal and neonatal deaths, prematurity, low birth weight, and severe and irreversible sequelae in some children. This study confirms the value of standard guidelines for its management.

  11. PNH revisited: Clinical profile, laboratory diagnosis and follow-up

    Directory of Open Access Journals (Sweden)

    Gupta P

    2009-01-01

    Full Text Available Background: Paroxysmal nocturnal hemoglobinuria (PNH is characterized by intravascular hemolysis, marrow failure, nocturnal hemoglobinuria and thrombophila. This acquired disease caused by a deficiency of glycosylphosphatidylinositol (GPI anchored proteins on the hematopoietic cells is uncommon in the Indian population. Materials and Methods: Data of patients diagnosed with PNH in the past 1 year were collected. Clinical data (age, gender, various presenting symptoms, treatment information and follow-up data were collected from medical records. Results of relevant diagnostic tests were documented i.e., urine analysis, Ham′s test, sucrose lysis test and sephacryl gel card test (GCT for CD55 and CD59. Results: A total of 5 patients were diagnosed with PNH in the past 1 year. Presenting symptoms were hemolytic anemia (n=4 and bone marrow failure (n=1. A GCT detected CD59 deficiency in all erythrocytes in 4 patients and CD55 deficiency in 2 patients. A weak positive PNH test for CD59 was seen in 1 patient and a weak positive PNH test for CD55 was seen in 3 patients. All patients were negative by sucrose lysis test. Ham′s test was positive in two cases. Patients were treated with prednisolone and/or androgen and 1 patient with aplastic anemia was also given antithymocyte globulin. A total of 4 patients responded with a partial recovery of hematopoiesis and 1 patient showed no recovery. None of the patients received a bone marrow transplant. Conclusion: The study highlights the diagnostic methods and treatment protocols undertaken to evaluate the PNH clone in a developing country where advanced methods like flowcytometry immunophenotyping (FCMI and bone marrow transplants are not routinely available.

  12. Parenchymal neurocysticercosis: follow-up and staging by MRI

    International Nuclear Information System (INIS)

    Dumas, J.L.; Visy, J.M.; Belin, C.; Gaston, A.; Goldlust, D.; Dumas, M.

    1997-01-01

    We describe the evolution of parenchymal cerebral cysticerci on MRI, to assess signs of early cyst degeneration. We studied 15 lesions in four treated and one untreated patient. MRI was performed before therapy and repeated in the 1st month after each course of anticysticercus drugs, every 4 months during the 1st year and then annually; the follow-up period was 8-48 months. Lesions were classified according to changes in four features: cyst content and capsule signal, gadolinium enhancement and oedema signal. We were able to recognise each of the pathological phases; five MRI stages were identified. Stage 1 showed oedema and/or nodular gadolinium enhancement in the tissue invasion phase; stage 2 was cerebrospinal fluid-like signal within a cyst in the vesicular phase; stage 3 showed a thick capsule with an impure liquid content signal and surrounding oedema, in the cystic phase; stage 4 showed the disappearance of the cyst fluid content signal in the degenerative phase; stage 5 showed a calcified lesion in the residual phase. Stage 1 lesions disappeared after therapy; the other progressed from one stage to another. Stage 4 indicated the end of viability of the parasite and determined the point after which treatment was useless. On T2-weighted images changes in the cyst content differed according to the history of the lesion; nodular low intensity followed the natural degeneration of the parasite and a mixed fluid signal with punctate low signal seemed to represent the specific result of therapy. MRI staging can help in the evaluation of indications for treatment and facilitate clinical therapeutic trials. (orig.). With 4 figs., 1 tab

  13. Descemet stripping endothelial keratoplasty: One-year follow-up

    Directory of Open Access Journals (Sweden)

    Nikolić Ljubiša

    2010-01-01

    Full Text Available Introduction. Sutureless transplantation of endothelium on a thin stromal carrier was introduced under the name of Descemet stripping endothelial keratoplasty (DSEK in 2004. It has become the treatment of choice of corneal oedema due to endothelial dysfunction. Objective. To investigate posterior lamellar graft attachment, central corneal thickness (CCT, astigmatism, and best corrected visual acuity (BCVA during one-year follow-up. Methods. Surgery was performed on one eye of 11 patients with pseudophakic bullous keratopathy and Fuchs’ dystrophy. The graft thick 150-200 μm and 8.0 mm in diameter was detached manually. The carrier of the recipient cornea was created by DSEK. The graft was folded in half, introduced into the anterior orbital chamber through a 5.0 mm cut on the limbus and attached by air bubble along the internal side of the recipient cornea. CCT and astigmatism were evaluated by corneal topography, and graft attachment by biomicroscopy. Results. One year after surgery, all grafts remained attached. Primary graft failure occurred in three eyes, probably due to the crushing effect of the forceps. BCVA was 20/30 (2 eyes, and 20/40 (6 eyes, CCT 643-728 μm, and astigmatism 1.1 D to 2.9 D. The peak values were reached three months after surgery, and did not change much afterwards. Conclusion. This is the first report on the long-term results of DSEK in our literature. The results are similar to those obtained by more experienced DSEK surgeons, and suggest that this procedure is safe and successful.

  14. Recent Progress on GRBs with Swift

    Science.gov (United States)

    Gehrels, Neil

    2012-01-01

    Gamma-ray bursts (GRBs) are powerful explosions, visible to high red shift, and thought to be the signature of black hole formation. The Swift Observatory has been detecting 100 bursts per year for 7 years and has greatly stimulated the field with new findings. Observations are made of the X-ray and optical afterglow from 1 minute after the burst, continuing for days. Evidence is building that the long and short duration subcategories of GRBs have very different origins: massive star core collapse to a black hole for long bursts and binary neutron star coalescence to a black hole for short bursts. The similarity to Type. II and Ia supernovae originating from young and old stellar progenitors is striking. Bursts are providing a new tool to study the high redshift universe. Swift has detected several events at z>S and one at z=9.4 giving metallicity measurements and other data on galaxies at previously inaccessible distances. The talk will present the latest results from Swift in GRB astronomy .

  15. Updated mortality follow-up among French AREVA NC workers: 1977-2004

    International Nuclear Information System (INIS)

    Metz-Flamant, C.; Rogel, A.; Samson, E.; Laurier, D.; Tirmarche, M.; Caer, S.; Quesne, B.; Acker, A.

    2008-01-01

    Full text: Introduction: This study has been established in order to evaluate the mortality of nuclear workers employed at the French company specialized in nuclear fuel cycle (AREVA NC ex COGEMA) and exposed to low level of ionizing radiation. The follow-up of the cohort has been extended recently. We present here a new analysis of the mortality based on an extended follow-up of the cohort by 10 years. Methods: Administrative data, vital status and causes of death were reconstructed for each worker. Standardized Mortality ratios (SMR) were computed using national mortality rates as external reference adjusted for sex, age and calendar year. Trend tests were computed to assess the association between different causes of death and radiation exposure considering adjustment on socioeconomic status (SES). Results: 93% of the 9,285 workers were male workers. They were followed for an average of 22 years, with a total number of person-years of 206,603. The % of subjects lost to follow-up was less than 1%. 1,052 deaths occurred during the total follow-up period. 98% of the causes of death were identified. Mean age at end of follow-up was 56 years. As excepted, a strong deficit was observed for all causes of death (SMR=0.64; 90% confidence interval CI : 0.60-0.67) and all cancer mortality (SMR=0.77; 90% confidence interval CI : 0.71-0.83). No significant excess was found for any of the considered causes of death. The all-causes and all cancers SMRs increased significantly with cumulative dose, but after adjusting on SES, these positive trends were no longer statistically significant. Among the 30 causes of deaths studied, significant trends were observed for colon, liver cancer and for non-cancer respiratory diseases. Conclusion: AREVA NC workers exposed to ionizing radiation have a lower mortality than the French national population, partly due to the Healthy Worker Effect. It is important to adjust on SES in the dose-effect relationship analysis. Although follow-up has

  16. Changes in occupational class differences in leisure-time physical activity: a follow-up study

    Directory of Open Access Journals (Sweden)

    Lahelma Eero

    2011-03-01

    Full Text Available Abstract Background Physical activity is known to have health benefits across population groups. However, less is known about changes over time in socioeconomic differences in leisure-time physical activity and the reasons for the changes. We hypothesised that class differences in leisure-time physical activity would widen over time due to declining physical activity among the lower occupational classes. We examined whether occupational class differences in leisure-time physical activity change over time in a cohort of Finnish middle-aged women and men. We also examined whether a set of selected covariates could account for the observed changes. Methods The data were derived from the Helsinki Health Study cohort mail surveys; the respondents were 40-60-year-old employees of the City of Helsinki at baseline in 2000-2002 (n = 8960, response rate 67%. Follow-up questionnaires were sent to the baseline respondents in 2007 (n = 7332, response rate 83%. The outcome measure was leisure-time physical activity, including commuting, converted to metabolic equivalent tasks (MET. Socioeconomic position was measured by occupational class (professionals, semi-professionals, routine non-manual employees and manual workers. The covariates included baseline age, marital status, limiting long-lasting illness, common mental disorders, job strain, physical and mental health functioning, smoking, body mass index, and employment status at follow-up. Firstly the analyses focused on changes over time in age adjusted prevalence of leisure-time physical activity. Secondly, logistic regression analysis was used to adjust for covariates of changes in occupational class differences in leisure-time physical activity. Results At baseline there were no occupational class differences in leisure-time physical activity. Over the follow-up leisure-time physical activity increased among those in the higher classes and decreased among manual workers, suggesting the emergence of

  17. Follow up of acute gonococcal urethritis in males treated with norfloxacin

    Directory of Open Access Journals (Sweden)

    Chari KVR

    1994-01-01

    Full Text Available This subject was undertaken to confirm the efficacy of norfloxacin in acute gonorrhoea and to note the relapse if any during the follow up period of 3 months. 27 male patients suffering from acute gonorrhoea were treated with 800 mgs of norfloxacin as single oral dose. In all cases, gonococci disappeared from urethral smears by 8 hours, urethral discharge subsided by 72 hrs, urine on naked eye examination cleared in 4 days except in 1 case and burning micturition subsided by 7 days. Cure rate was 100% in the study. No relapse was found at the end of follow up of 3 months. No adverse reactions were observed to norfloxacin except headache in 2 cases. Norfloxacin was safe and effective in the treatment of acute gonorrhoea.

  18. Association between subjective memory complaints and nursing home placement: a four-year follow-up

    DEFF Research Database (Denmark)

    Waldorff, Frans Boch; Siersma, Volkert; Waldemar, Gunhild

    2009-01-01

    OBJECTIVE: In order to evaluate whether elderly persons with subjective memory complaints may be regarded as a group of potentially vulnerable patients who need close follow-up, we investigated the risk of nursing home placement during a 4-year follow-up period. METHODS: Prospective cohort survey...... nursing home placements were observed. Subjective memory complaints were associated with an adjusted Hazard Ratio (HR) of 2.59 for nursing home placement. Other statistical significant covariates were MMSE .../depression (HR = 4.74). The effect of subjective memory complaints is seen to moderate when subjects are older. CONCLUSION: The data of this study indicated that in an elderly primary care population the presence of subjective memory complaints was a significant independent predictor for nursing home placement...

  19. Long-term follow-up and outcome in patients with recurrent respiratory laryngeal papillomatosis

    DEFF Research Database (Denmark)

    Rasmussen, Eva Rye; Schnack, Didde T; Jørkov, Andreas Schjellerup

    2017-01-01

    adult and four juvenile patients were identified. The male-to-female ratio was 2.4. In the adult population, the mean age at onset was 45 years. The median number of surgeries was four (interquartile range: 2.8). The mean follow-up time was 8.7 years (range: 7 days-30 years). Three cases of malignant...... transformation were observed. In the juvenile population, the mean age of onset was 8.5 years (range: 3-12 years). The mean follow-up time was 11.5 years (range: 2-23 years), and the number of surgeries per year at risk was one/year. CO2-laser and microdebrider were the surgical techniques usually employed. 43...

  20. Marked point process framework for living probabilistic safety assessment and risk follow-up

    International Nuclear Information System (INIS)

    Arjas, Elja; Holmberg, Jan

    1995-01-01

    We construct a model for living probabilistic safety assessment (PSA) by applying the general framework of marked point processes. The framework provides a theoretically rigorous approach for considering risk follow-up of posterior hazards. In risk follow-up, the hazard of core damage is evaluated synthetically at time points in the past, by using some observed events as logged history and combining it with re-evaluated potential hazards. There are several alternatives for doing this, of which we consider three here, calling them initiating event approach, hazard rate approach, and safety system approach. In addition, for a comparison, we consider a core damage hazard arising in risk monitoring. Each of these four definitions draws attention to a particular aspect in risk assessment, and this is reflected in the behaviour of the consequent risk importance measures. Several alternative measures are again considered. The concepts and definitions are illustrated by a numerical example

  1. Therapeutic follow-up in hospitalization: social inclusion, recovery of citizenship and respect for individuality

    Directory of Open Access Journals (Sweden)

    Regina Célia Fiorati

    2008-01-01

    Full Text Available This study was carried out in a psychiatric crisis hospitalization unit, with the aim of drawing up a proposal for implementing therapeutic follow-up as part of the therapeutic program at this unit. The concept of therapeutic follow-up was envisaged as an important resource to be included in psychosocial rehabilitation projects, with the following goals: linking users with extra-hospital services, avoiding re-hospitalization and achieving inclusion in social networks. The study consisted of an exploratory-descriptive case study with a qualitative approach to data. Participant observation and a field diary were the techniques used for gathering and recording data. The difficulties experienced were correlated with the spheres of social networks, family, institutional relationships and society. The results included heeding the patient's and the family's suffering and including users in social networks, extra-hospital services and community organizations.

  2. Follow-up of aortic intramural hematoma by electron beam CT

    International Nuclear Information System (INIS)

    Zhi Aihua; Dai Ruping; Jiang Shiliang; Jin Jinglin; Chao Cehng; Bao Hua; Wu Haiying; Sun Lizhong

    2006-01-01

    Objective: To evaluate the dynamic changing and prognosis of aortic intramural hematoma (IMH) by electron beam CT(EBCT). Methods: A retrospective study was performed during a period of time from January. 2002 to September 2004. Twenty-three patients with aortic IMH were scanned by EBCT more than 2 times. The patients were followed-up for 4-405 days (mean 105.8 days). Mean follow-up was 105.84 days. In this group 23 patients (19 men and 4 women, aged from 30 to 81 years, mean 57.78 years) who had been undergone EBCT were diagnosed with IMH. EBCT scanner was used with a model of Imatron C-150XP. Contrast-enhanced continuous volume scanning (CVS) was performed. The slice thickness was 6 mm or 3 mm with an acquisition time of 100 milliseconds. A total amount of contrast media (Ultravist 300 or 320, or Ominpaque 300 or 320 mg/ml) of 80-100 ml was used with the rate of 3.5- 4.5 ml/s. The scan delayed time was 18-30 s. Results: Four patients with Standford A IMH were diagnosed. Among them, 3 patients were observed in complete regression, 1 patient was observed without changing. Nineteen patients with Standford B IMH were diagnosed. Among them, 9 patients were observed in complete regression, 4 patients were observed in incomplete regression, 4 patients were observed without changing, 2 patients were observed in progression on EBCT. From 4 days to 15 days, IMH was observed without change or worse. From 16 days to 30 days IMH was observed in regression. Conclusion: EBCT was a very useful tool for detecting and following up of IMH. The different features of the involved aortic walls shown on EBCT were used for planning surgery. (authors)

  3. A New Era of Submillimeter GRB Afterglow Follow-Ups with the Greenland Telescope

    Directory of Open Access Journals (Sweden)

    Yuji Urata

    2015-01-01

    Full Text Available Planned rapid submillimeter (submm gamma-ray-bursts (GRBs follow-up observations conducted using the Greenland Telescope (GLT are presented. The GLT is a 12-m submm telescope to be located at the top of the Greenland ice sheet, where the high altitude and dry weather porvide excellent conditions for observations at submm wavelengths. With its combination of wavelength window and rapid responding system, the GLT will explore new insights on GRBs. Summarizing the current achievements of submm GRB follow-ups, we identify the following three scientific goals regarding GRBs: (1 systematic detection of bright submm emissions originating from reverse shock (RS in the early afterglow phase, (2 characterization of forward shock and RS emissions by capturing their peak flux and frequencies and performing continuous monitoring, and (3 detections of GRBs at a high redshift as a result of the explosion of first generation stars through systematic rapid follow-ups. The light curves and spectra calculated by available theoretical models clearly show that the GLT could play a crucial role in these studies.

  4. Paraquat induced lung injury: long-term follow-up of HRCT

    International Nuclear Information System (INIS)

    Kim, Young Tong; Kim, Hyun Cheol; Bae, Won Kyung; Kim, Il Young; Im, Han Hyek

    2004-01-01

    To determine the long-term follow-up CT findings of paraquat-induced lung injury. Six patients who ingested paraquat underwent sequential follow-up CT scanning during a period of at least six months, and the results were analysed. Scans were obtained 1-6 (mean, 3.3) time during a 7-84 (mean, 25.7) months period, and the findings at 1-2 months, 3-12 months, 1-2 years, 2-3 years and more than above 7 years after poisoning were analyzed. We observed irregular-shaped areas of consolidation with traction bronchiectasis at 1-2 months (5/5), irregular-shaped consolidation and ground-glass opacity (5/5) at 3-12 months, and irregular-shaped consolidations/ground-glass opacity (4/5) and focal honeycombing (1/5) one year later. In the same patients, follow-up CT scans showed that some areas of focal consolidation could not be visualized and the radio-opacity of the lesions had decreased. The HRCT findings of paraquat-induced lung injury were irregular shaped areas of consolidation 1-2 months after ingestion, and irregular-shaped consolidation and ground-glass opacity or focal honeycombing 3-12 months later. At this thim slight improvement was observed

  5. Paraquat induced lung injury: long-term follow-up of HRCT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Tong; Kim, Hyun Cheol; Bae, Won Kyung; Kim, Il Young; Im, Han Hyek [Soonchunhyang Univ., Chunan (Korea, Republic of)

    2004-03-01

    To determine the long-term follow-up CT findings of paraquat-induced lung injury. Six patients who ingested paraquat underwent sequential follow-up CT scanning during a period of at least six months, and the results were analysed. Scans were obtained 1-6 (mean, 3.3) time during a 7-84 (mean, 25.7) months period, and the findings at 1-2 months, 3-12 months, 1-2 years, 2-3 years and more than above 7 years after poisoning were analyzed. We observed irregular-shaped areas of consolidation with traction bronchiectasis at 1-2 months (5/5), irregular-shaped consolidation and ground-glass opacity (5/5) at 3-12 months, and irregular-shaped consolidations/ground-glass opacity (4/5) and focal honeycombing (1/5) one year later. In the same patients, follow-up CT scans showed that some areas of focal consolidation could not be visualized and the radio-opacity of the lesions had decreased. The HRCT findings of paraquat-induced lung injury were irregular shaped areas of consolidation 1-2 months after ingestion, and irregular-shaped consolidation and ground-glass opacity or focal honeycombing 3-12 months later. At this thim slight improvement was observed.

  6. [Obstetrical follow-up and perinatal prognosis in drug addict pregnant women].

    Science.gov (United States)

    Fanjeaux, B; Braconnier, A; Clerc-Urmès, I; Morel, O; Gauchotte, E

    2018-02-01

    To identify the factors associated with a good obstetric follow-up and a good perinatal prognosis, in order to adapt the management of pregnant women with addiction to opiates. A retrospective study was carried out in our maternity between January 2012 and December 2014, including 104 women who were addicted to opiates, whether or not they were substituted, with or without associated consumptions, regardless of the term of delivery beyond 22 weeks of amenorrhea. A good obstetrical follow-up was observed by 32.7% of women. The father's presence (OR=3.9; P=0.0113) and investment in pregnancy (OR=4.4; P=0.0029), as well as the desired character of the pregnancy (OR=4.5; P=0.0008) appeared to be associated with the quality of the observed follow-up. Preterm deliveries (11.8 versus 35.8%; P=0.0103), and social measures taken at the discharge of the newborn from the maternity (2.9 versus 24.3%, P=0.0057) were less frequent. A good perinatal prognosis was found for 29.8% of the cases. Associated consumptions <3 (OR=2.6 [1.1-6.2]; P=0.0281) confirmed by negative urine drug screening (OR=2.9 [1.1-7.8]; P=0.0307) were more numerous. Although the follow-up and the perinatal prognosis of these pregnancies have improved considerably in recent years, it seems necessary to further optimize their management. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  7. Fifteen-year follow-up of quality of life in type 1 diabetes mellitus.

    Science.gov (United States)

    van Dijk, Peter R; Logtenberg, Susan Jj; Groenier, Klaas H; Keers, Joost C; Bilo, Henk Jg; Kleefstra, Nanne

    2014-08-15

    To evaluate metabolic control and health-related quality of life (HRQOL) in a type 1 diabetes mellitus (T1DM) population. As part of a prospective cohort study, 283 T1DM patients treated with various insulin treatment modalities including multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) were examined annually. HRQOL was measured using the SF-36 and EuroQol questionnaires. Data regarding HRQOL, glycaemic and metabolic control from baseline and follow-up measures in 2002 and 2010 were analysed. Linear mixed models were used to calculate estimated values and differences between the three moments in time and the three treatment modalities. Significant changes [mean Δ (95%CI)] in body mass index [2.4 kg/m(2) (1.0, 3.8)], systolic blood pressure [-6.4 mmHg (-11.4, -1.3)] and EuroQol-VAS [-7.3 (-11.4, -3.3)] were observed over time. In 2010, 168 patients were lost to follow-up. Regarding mode of therapy, 52 patients remained on MDI, 28 remained on CSII, and 33 patients switched from MDI to CSII during follow-up. Among patients on MDI, HRQOL decreased significantly over time: mental component summary [-9.8 (-16.3, -3.2)], physical component summary [-8.6 (-15.3, -1.8)] and EuroQol-VAS [-8.1 (-14.0, -2.3)], P VAS decreased [-9.6 (-17.5, -1.7)]. None of the changes over time in HRQOL differed significantly with the changes over time within the other treatment groups. No differences with respect to metabolic and HRQOL parameters between the various insulin treatment modalities were observed after 15 years of follow-up in T1DM patients.

  8. Radiographic follow-up study of Little Leaguer's shoulder

    Energy Technology Data Exchange (ETDEWEB)

    Kanematsu, Yoshiji; Iwase, Takenobu [Tokushima National Hospital, Department of Orthopaedic Surgery, Tokushima (Japan); Matsuura, Tetsuya; Suzue, Naoto; Sairyo, Koichi [University of Tokushima Graduate School, Department of Orthopedics, Institute of Health Bioscience, Tokushima (Japan); Kashiwaguchi, Shinji [Japan Community Health Care Organization, Tokyo Shinjuku Medical Center, Department of Orthopaedic Surgery, Tokyo (Japan); Iwame, Toshiyuki [Tokushima Prefectural Central Hospital, Department of Orthopaedic Surgery, Tokushima (Japan)

    2015-01-15

    Little Leaguer's shoulder is a syndrome involving the proximal humeral epiphyseal plate. Conservative treatment usually resolves the symptoms. However, there are no reports of a radiographic follow-up study of this disease. The purpose of this study was to show the radiographic healing process of Little Leaguer's shoulder. A total of 19 male baseball players diagnosed as having Little Leaguer's shoulder were retrospectively evaluated. The mean age at first presentation was 12.7 years. External rotation anteroposterior radiographs of the shoulder were taken. All patients were treated with rest from throwing, and no throwing was recommended until remodeling was confirmed. Follow-up radiographs were taken at 1-month intervals to assess healing. All patients were observed until healing was confirmed radiographically, after which they returned to baseball. The mean follow-up period was 8.5 months. In addition to radiography, patients were asked whether they had any symptoms and whether they had been able to return to baseball. At the first examination, radiographs showed a wider epiphyseal plate of the throwing side compared with the asymptomatic contralateral shoulder. Healing was observed in all cases. Healing occurred first along the medial side and was then extended laterally. The mean time required for healing was 4.7 months. All patients were able to return to playing baseball at their pre-injury level of play and were asymptomatic when examined at the final follow-up. The healing process of Little Leaguer's shoulder advanced from medial to lateral, and healing was achieved about 5 months after initial examination. (orig.)

  9. Nurse-led follow-up at home vs. conventional medical outpatient clinic follow-up in patients with incurable upper gastrointestinal cancer: a randomized study.

    Science.gov (United States)

    Uitdehaag, Madeleen J; van Putten, Paul G; van Eijck, Casper H J; Verschuur, Els M L; van der Gaast, Ate; Pek, Chulja J; van der Rijt, Carin C D; de Man, Rob A; Steyerberg, Ewout W; Laheij, Robert J F; Siersema, Peter D; Spaander, Manon C W; Kuipers, Ernst J

    2014-03-01

    Upper gastrointestinal cancer is associated with a poor prognosis. The multidimensional problems of incurable patients require close monitoring and frequent support, which cannot sufficiently be provided during conventional one to two month follow-up visits to the outpatient clinic. To compare nurse-led follow-up at home with conventional medical follow-up in the outpatient clinic for patients with incurable primary or recurrent esophageal, pancreatic, or hepatobiliary cancer. Patients were randomized to nurse-led follow-up at home or conventional medical follow-up in the outpatient clinic. Outcome parameters were quality of life (QoL), patient satisfaction, and health care consumption, measured by different questionnaires at one and a half and four months after randomization. As well, cost analyses were done for both follow-up strategies in the first four months. In total, 138 patients were randomized, of which 66 (48%) were evaluable. At baseline, both groups were similar with respect to clinical and sociodemographic characteristics and health-related QoL. Patients in the nurse-led follow-up group were significantly more satisfied with the visits, whereas QoL and health care consumption within the first four months were comparable between the two groups. Nurse-led follow-up was less expensive than conventional medical follow-up. However, the total costs for the first four months of follow-up in this study were higher in the nurse-led follow-up group because of a higher frequency of visits. The results suggest that conventional medical follow-up is interchangeable with nurse-led follow-up. A cost utility study is necessary to determine the preferred frequency and duration of the home visits. Copyright © 2014 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

  10. Klenot near-Earth-object follow-up program --- next generation

    Science.gov (United States)

    Ticha, J.; Tichy, M.; Kocer, M.; Honkova, M.

    2014-07-01

    NEO research is a great challenge just now --- for science, for exploration, and for planetary defence. Therefore NEO discoveries, astrometric follow-up, orbit computations as well as physical studies are of high interest both to science community and humankind. The KLENOT Project of the Klet Observatory, South Bohemia, Czech Republic, has pursued the confirmation, early follow-up, long-arc follow-up and recovery of Near Earth Objects since 2002. Tens of thousands astrometric measurements has helped to improve the inventory of NEOs as well as to understand the NEO population. It was ranked among the world most prolific professional NEO follow-up programmes during its first phase from 2002 to 2008. A fundamental improvement of the 1.06-m KLENOT Telescope was started in autumn 2008. A new computer controlled paralactic mount was built to substantially increase telescope-time efficiency, the number of observations, their accuracy and limiting magnitude. The testing observations of the KLENOT Telescope Next Generation were started in October 2011. The new more efficient CCD camera FLI ProLine 230 was installed in summer 2013. The original Klet Software Package has been continually upgraded over the past two decades of operation. Along with huge hardware changes we have decided for essential changes in software and the whole KLENOT work-flow. Using the current higher computing power available, enhancing and updating our databases and astrometry program, the core of our software package, will prove highly beneficial. Moreover, the UCAC4 as the more precise astrometric star catalog was implemented. Both the system and strategy for the NEO follow-up observation used in the framework of the KLENOT Project are described here, including methods for selecting useful and important targets for NEO follow-up astrometry. Methods and techniques used for the KLENOT Project are also discussed. Sources of particular inaccuracies of astrometric measurements as input data for orbit

  11. Going the Distance: Mapping Host Galaxies of LIGO and VIRGO Sources in Three Dimensions using Local Cosmography and Targeted Follow-Up

    Science.gov (United States)

    Singer, Leo P.; Chen, Hsin-Yu; Holz, Daniel E.; Farr, Will M.; Price, Larry R.; Raymond, Vivien; Cenko, S. Bradley; Gehrels, Neil; Cannizzo, John K.; Kasliwal, Mansi M.; hide

    2016-01-01

    The Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) discovered gravitational waves (GWs) from a binary black hole merger in 2015 September and may soon observe signals from neutron star mergers. There is considerable interest in searching for their faint and rapidly fading electromagnetic (EM) counterparts, though GW position uncertainties are as coarse as hundreds of square degrees. Because LIGO's sensitivity to binary neutron stars is limited to the local universe, the area on the sky that must be searched could be reduced by weighting positions by mass, luminosity, or star formation in nearby galaxies. Since GW observations provide information about luminosity distance, combining the reconstructed volume with positions and redshifts of galaxies could reduce the area even more dramatically. A key missing ingredient has been a rapid GW parameter estimation algorithm that reconstructs the full distribution of sky location and distance. We demonstrate the first such algorithm, which takes under a minute, fast enough to enable immediate EM follow-up. By combining the three-dimensional posterior with a galaxy catalog, we can reduce the number of galaxies that could conceivably host the event by a factor of 1.4, the total exposure time for the Swift X-ray Telescope by a factor of 2, the total exposure time for a synoptic optical survey by a factor of 2, and the total exposure time for a narrow-field optical telescope by a factor of 3. This encourages us to suggest a new role for small field of view optical instruments in performing targeted searches of the most massive galaxies within the reconstructed volumes.

  12. GOING THE DISTANCE: MAPPING HOST GALAXIES OF LIGO AND VIRGO SOURCES IN THREE DIMENSIONS USING LOCAL COSMOGRAPHY AND TARGETED FOLLOW-UP

    International Nuclear Information System (INIS)

    Singer, Leo P.; Cenko, S. Bradley; Gehrels, Neil; Cannizzo, John; Chen, Hsin-Yu; Holz, Daniel E.; Farr, Ben; Farr, Will M.; Veitch, John; Berry, Christopher P. L.; Mandel, Ilya; Price, Larry R.; Raymond, Vivien; Kasliwal, Mansi M.; Nissanke, Samaya; Coughlin, Michael; Urban, Alex L.; Vitale, Salvatore; Mohapatra, Satya; Graff, Philip

    2016-01-01

    The Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) discovered gravitational waves (GWs) from a binary black hole merger in 2015 September and may soon observe signals from neutron star mergers. There is considerable interest in searching for their faint and rapidly fading electromagnetic (EM) counterparts, though GW position uncertainties are as coarse as hundreds of square degrees. Because LIGO’s sensitivity to binary neutron stars is limited to the local universe, the area on the sky that must be searched could be reduced by weighting positions by mass, luminosity, or star formation in nearby galaxies. Since GW observations provide information about luminosity distance, combining the reconstructed volume with positions and redshifts of galaxies could reduce the area even more dramatically. A key missing ingredient has been a rapid GW parameter estimation algorithm that reconstructs the full distribution of sky location and distance. We demonstrate the first such algorithm, which takes under a minute, fast enough to enable immediate EM follow-up. By combining the three-dimensional posterior with a galaxy catalog, we can reduce the number of galaxies that could conceivably host the event by a factor of 1.4, the total exposure time for the Swift X-ray Telescope by a factor of 2, the total exposure time for a synoptic optical survey by a factor of 2, and the total exposure time for a narrow-field optical telescope by a factor of 3. This encourages us to suggest a new role for small field of view optical instruments in performing targeted searches of the most massive galaxies within the reconstructed volumes.

  13. GOING THE DISTANCE: MAPPING HOST GALAXIES OF LIGO AND VIRGO SOURCES IN THREE DIMENSIONS USING LOCAL COSMOGRAPHY AND TARGETED FOLLOW-UP

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Leo P.; Cenko, S. Bradley; Gehrels, Neil; Cannizzo, John [Astroparticle Physics Laboratory, NASA Goddard Space Flight Center, Mail Code 661, Greenbelt, MD 20771 (United States); Chen, Hsin-Yu; Holz, Daniel E.; Farr, Ben [Department of Physics, Enrico Fermi Institute, and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States); Farr, Will M.; Veitch, John; Berry, Christopher P. L.; Mandel, Ilya [School of Physics and Astronomy, University of Birmingham, Birmingham, B15 2TT (United Kingdom); Price, Larry R.; Raymond, Vivien [LIGO Laboratory, California Institute of Technology, Pasadena, CA 91125 (United States); Kasliwal, Mansi M. [Cahill Center for Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Nissanke, Samaya [Institute of Mathematics, Astrophysics and Particle Physics, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen (Netherlands); Coughlin, Michael [Department of Physics and Astronomy, Harvard University, Cambridge, MA 02138 (United States); Urban, Alex L. [Leonard E. Parker Center for Gravitation, Cosmology, and Astrophysics, University of Wisconsin–Milwaukee, Milwaukee, WI 53201 (United States); Vitale, Salvatore; Mohapatra, Satya [LIGO Laboratory, Massachusetts Institute of Technology, 185 Albany Street, Cambridge, MA 02139 (United States); Graff, Philip [Department of Physics, University of Maryland, College Park, MD 20742 (United States)

    2016-09-20

    The Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) discovered gravitational waves (GWs) from a binary black hole merger in 2015 September and may soon observe signals from neutron star mergers. There is considerable interest in searching for their faint and rapidly fading electromagnetic (EM) counterparts, though GW position uncertainties are as coarse as hundreds of square degrees. Because LIGO’s sensitivity to binary neutron stars is limited to the local universe, the area on the sky that must be searched could be reduced by weighting positions by mass, luminosity, or star formation in nearby galaxies. Since GW observations provide information about luminosity distance, combining the reconstructed volume with positions and redshifts of galaxies could reduce the area even more dramatically. A key missing ingredient has been a rapid GW parameter estimation algorithm that reconstructs the full distribution of sky location and distance. We demonstrate the first such algorithm, which takes under a minute, fast enough to enable immediate EM follow-up. By combining the three-dimensional posterior with a galaxy catalog, we can reduce the number of galaxies that could conceivably host the event by a factor of 1.4, the total exposure time for the Swift X-ray Telescope by a factor of 2, the total exposure time for a synoptic optical survey by a factor of 2, and the total exposure time for a narrow-field optical telescope by a factor of 3. This encourages us to suggest a new role for small field of view optical instruments in performing targeted searches of the most massive galaxies within the reconstructed volumes.

  14. Rapid variability of blazar 3C 279 during flaring states in 2013-2014 with joint FERMI-LAT, NuSTAR, swift, and ground-based multi-wavelength observations

    DEFF Research Database (Denmark)

    Hayashida, M.; Nalewajko, K.; Madejski, G. M.

    2015-01-01

    reaching the highest flux level measured in this object since the beginning of the Fermi mission, with F (E> 100 MeV) of 10-5 photons cm-2 s-1, and with a flux-doubling time scale as short as 2 hr. The y-ray spectrum during one of the flares was very hard, with an index of Γγ = 1.7 ± 0.1, which is rarely...... seen in flat-spectrum radio quasars. The lack of concurrent optical variability implies a very high Compton dominance parameter Lγ/Lsyn > 300. Two 1 day NuSTAR observations with accompanying Swift pointings were separated by 2 weeks, probing different levels of source activity. While the 0.5-70 keV X-ray......) extremely low jet magnetization with LB/Lj 10-4. ≲ - We also find that single-zone models that match the observed γ-ray and optical spectra cannot satisfactorily explain the production of X-ray emission....

  15. Ergonomic Training Reduces Musculoskeletal Disorders among Office Workers: Results from the 6-Month Follow-Up

    Science.gov (United States)

    Mahmud, Norashikin; Kenny, Dianna Theadora; Md Zein, Raemy; Hassan, Siti Nurani

    2011-01-01

    Background: Musculoskeletal disorders are commonly reported among computer users. This study explored whether these disorders can be reduced by the provision of ergonomics education. Methods: A cluster randomised controlled trial was conducted in which 3 units were randomised for intervention and received training, and 3 units were given a leaflet. The effect of intervention on workstation habits, musculoskeletal disorders, days and episodes of sick leave, and psychological well-being were assessed. Results: A significant improvement in workstation habits was found, and the differences remained significant at the follow-up time point for keyboard, mouse, chair, and desk use. The largest reduction in the percentage of musculoskeletal disorders was in the neck region (−42.2%, 95% CI −60.0 to −24.4). After adjusting for baseline values, significant differences were found at the follow-up time point in the neck, right shoulder, right and left upper limbs, lower back, and right and left lower limbs. No significant differences were found for the days and episodes of sick leave or the psychological well-being among workers after the intervention. Conclusion: Consistent reductions were observed for all musculoskeletal disorders at the follow-up time point, although the difference was not statistically significant for the upper back. The improvements in the musculoskeletal disorders did not translate into fewer days lost from work or improved psychological well-being. PMID:22135582

  16. Adolescent Kawasaki disease: usefulness of 64-slice CT coronary angiography for follow-up investigation

    Energy Technology Data Exchange (ETDEWEB)

    Carbone, Iacopo; Cannata, David; Algeri, Emanuela; Galea, Nicola; Napoli, Alessandro; Catalano, Carlo; Passariello, Roberto; Francone, Marco [Sapienza University of Rome, Department of Radiological, Onchological and Anatomopathological Sciences, Policlinico Umberto I, Rome (Italy); De Zorzi, Andrea [Bambino Gesu Hospital, Cardiology Division, Rome (Italy); Bosco, Giovanna; D' Agostino, Rita [Sapienza University of Rome, Unit of Paediatric Cardiology, Policlinico Umberto I, Rome (Italy); Menezes, Leon [University College of London, Institute of Nuclear Medicine, London (United Kingdom)

    2011-09-15

    Kawasaki disease (KD) is a systemic vasculitis that mainly affects coronary arteries in children, and requires regular follow-up from the time of diagnosis. To evaluate the feasibility of 64-slice CT angiography (CTA) for follow-up of patients with KD using previously performed invasive catheter coronary angiography (CCA) as reference standard. The study group comprised 12 patients (age 17.6 {+-} 2.9 years, mean{+-}SD) with a diagnosis of KD and a previously performed CCA (interval, 32.6 {+-} 13.5 months) who underwent 64-slice cardiac CTA. The quality of the images for establishing the presence of coronary abnormalities was determined by two observers. The CTA findings were compared with those from the prior CCA. Adequate image quality was obtained in all patients. Mean effective dose for CTA was 6.56 {+-} 0.95 mSv. CTA allowed accurate identification, characterization and measurement of all coronary aneurysms (n = 32), stenoses (n = 3) and occlusions (n = 9) previously demonstrated by CCA. One patient with disease progression went on to have percutaneous coronary intervention. Coronary lesions were reliably evaluated by 64-slice CTA in the follow-up of compliant patients with KD, reducing the need for repeated diagnostic invasive CCA. Hence, in an adequately selected patient population, the role of CCA could be limited almost only to therapeutic procedures. (orig.)

  17. Aneurysm treatment response prediction in follow up black blood magnetic resonance imaging. A case series study

    Science.gov (United States)

    Petridis, Athanasios K.; Suresh, Marian; Cornelius, Jan F.; Tortora, Angelo; Steiger, Hans Jakob; Turowski, Bernd; May, Rebecca

    2018-01-01

    Black blood magnetic resonance imaging (MRI)is a promising imaging tool in predicting aneurysm rupture. Could it be also valuable in evaluating the treatment effect of endovascular and conservative treated aneurysms? Two patients were treated with stent and coil and one with Aspirine (ASS). Correlation of treatment response and contrast enhancement of the aneurysm wall is examined. In the first case stenting failed to treat the aneurysm and contrast enhancement in the wall did never subside during follow up black blood MRI. In the second case the aneurysm responded well to stenting and decreased in size, which was correlating significantly with attenuation of contrast enhancement in black blood MRI. In the third case the aneurysm responded to ASS treatment by decreasing in size as shown in follow up MR-angiography and the contrast enhancement in its wall decreased after 8 months of therapy. Black blood MRI seems to be a promising tool not only in predicting aneurysms at risk of rupture, but also in observing treatment responses after endovascular procedures or even Aspirine administration. When contrast enhancement decreases, aneurysm treatment seems to be successful as can be shown in decreasing size in the follow up angiography. PMID:29619161

  18. Aneurysm treatment response prediction in follow up black blood magnetic resonance imaging. A case series study

    Directory of Open Access Journals (Sweden)

    Athanasios K. Petridis

    2018-03-01

    Full Text Available Black blood magnetic resonance imaging (MRIis a promising imaging tool in predicting aneurysm rupture. Could it be also valuable in evaluating the treatment effect of endovascular and conservative treated aneurysms? Two patients were treated with stent and coil and one with Aspirine (ASS. Correlation of treatment response and contrast enhancement of the aneurysm wall is examined. In the first case stenting failed to treat the aneurysm and contrast enhancement in the wall did never subside during follow up black blood MRI. In the second case the aneurysm responded well to stenting and decreased in size, which was correlating significantly with attenuation of contrast enhancement in black blood MRI. In the third case the aneurysm responded to ASS treatment by decreasing in size as shown in follow up MR-angiography and the contrast enhancement in its wall decreased after 8 months of therapy. Black blood MRI seems to be a promising tool not only in predicting aneurysms at risk of rupture, but also in observing treatment responses after endovascular procedures or even Aspirine administration. When contrast enhancement decreases, aneurysm treatment seems to be successful as can be shown in decreasing size in the follow up angiography.

  19. Planck early results. IX. XMM-Newton follow-up for validation of Planck cluster candidates

    DEFF Research Database (Denmark)

    Poutanen, T.; Natoli, P.; Polenta, G.

    2011-01-01

    We present the XMM-Newton follow-up for confirmation of Planck cluster candidates. Twenty-five candidates have been observed to date using snapshot (∼10 ks) exposures, ten as part of a pilot programme to sample a low range of signal-to-noise ratios (4 ... programme has helped to optimise the Planck candidate selection process. It has also provided a preview of the X-ray properties of these newly-discovered clusters, allowing comparison with their SZ properties, and to the X-ray and SZ properties of known clusters observed in the Planck survey. Our results...

  20. Comparing the effects of education using telephone follow-up and smartphone-based social networking follow-up on self-management behaviors among patients with hypertension.

    Science.gov (United States)

    Najafi Ghezeljeh, Tahereh; Sharifian, Sanaz; Nasr Isfahani, Mehdi; Haghani, Hamid

    2018-03-05

    Little is known about the benefits of social networks in the management of patients. The aim of this study was to compare the effects of self-management (SM) education using telephone follow-up and mobile phone-based social networking on SM behaviors among patients with hypertension. This randomized clinical trial was conducted with 100 patients. They were randomly allocated to four groups: (i) control, (ii) SM training without follow-up, (iii) telephone follow-up and (iv) smartphone-based social networking follow-up. The hypertension SM behavior questionnaire was used for data collection before and six weeks after the study. Those patients who underwent SM education training (with and without follow-up) had statistically significant differences from those in the control group in terms of SM behaviors (p networking follow-up influenced SM behaviors among patients with hypertension.

  1. Newly diagnosed incident dizziness of older patients: a follow-up study in primary care

    Directory of Open Access Journals (Sweden)

    Hummers-Pradier Eva

    2011-06-01

    Full Text Available Abstract Background Dizziness is a common complaint of older patients in primary care, yet not much is known about the course of incident dizziness. The aim of the study was to follow-up symptoms, subjective impairments and needs of older patients (≥65 with incident dizziness and to determine predictors of chronic dizziness. Furthermore, we analysed general practitioners' (GPs' initial diagnoses, referrals and revised diagnoses after six months. Methods An observational study was performed in 21 primary care practices in Germany, including a four-week and six-month follow-up. A questionnaire comprising characteristic matters of dizziness and a series of validated instruments was completed by 66 participants during enrolment and follow-up (after 1 month and 6 months. After six months, chart reviews and face-to-face interviews were also performed with the GPs. Results Mean scores of dizziness handicap, depression and quality of life were not or only slightly affected, and did not deteriorate during follow-up; however, 24 patients (34.8% showed a moderate or severe dizziness handicap, and 43 (62.3% showed a certain disability in terms of quality of life at the time of enrolment. In multivariate analysis, n = 44 patients suffering from chronic dizziness (dependent variable, i.e. relapsing or persistent at six months initially had a greater dizziness handicap (OR 1.42, 95%CI 1.05-1.47 than patients with transient dizziness. GPs referred 47.8% of the patients to specialists who detected two additional cases of benign paroxysmal positional vertigo (BPPV. Conclusions New-onset dizziness relapsed or persisted in a considerable number of patients within six months. This was difficult to predict due to the patients' heterogeneous complaints and characteristics. Symptom persistence does not seem to be associated with deterioration of the psychological status in older primary care patients. Management strategies should routinely consider BPPV as

  2. Predictors of residual flow in embolized intracranial ruptured aneurysms at early follow-up.

    Science.gov (United States)

    Serafin, Zbigniew; Strześniewski, Piotr; Beuth, Wojciech

    2014-01-01

    The possibility of recanalization and the need for retreatment are the most important drawbacks of intracranial aneurysm embolization. The purpose of the study was to prospectively analyze the results of early follow-up angiography of embolized ruptured aneurysms in an attempt to determine factors predicting the presence of residual flow. Evaluation included 72 patients with 72 aneurysms, which were followed-up 3 months after the treatment. Analysis of residual flow predictors included: age and gender, clinical state in Hunt-Hess scale, aneurysm localization, aneurysm three dimensions and volume, neck width, sac-to-neck ratio, initial result of embolization, number of coils used and the use of hydrogel coils and stents. Mean sac diameter was 6.5±3.9 mm, and mean neck width was 2.9±1.4 mm. Follow-up angiography presented residual flow in 26 aneurysms (36.1%): class 2 in 8 aneurysms (11.1%), and class 3 in 18 cases (25.0%). Stable aneurysm filling was observed in 45 cases (62.5%), progression of residual flow in 25 cases (34.7%), and regression in 2 cases (2.8%). According to ROC analysis independent predictors of residual flow were aneurysm neck diameter (AUC 0.857, 95% CI: 0.755-0.928, p<0.0001) and sac-to-neck ratio (AUC 0.817, 95% CI: 0.708-0.898, p<0.0001). Cut-off point of the ROC curve was established at 2.8 mm for neck diameter, and 1.73 for sac-to-neck ratio. Aneurysm neck diameter and sac-to-neck ratio are independently related to the residual flow in embolized ruptured aneurysms at early follow-up.

  3. Sacral nerve stimulation for faecal incontinence: medium-term follow-up from a single institution.

    Science.gov (United States)

    Patton, Vicki; Abraham, Earl; Lubowski, David Z

    2017-06-01

    Most studies on sacral nerve stimulation (SNS) are either single-centre with small numbers of patients or multi-centre studies. We present the medium-term follow-up results from a single centre for 127 patients undergoing SNS. Consecutive patients treated with SNS for faecal incontinence had preoperative baseline St Mark's continence scores, faecal incontinence quality of life (FIQL) measures and anorectal physiology studies. Follow-up was a postal questionnaire concerning continence, FIQL, patient-perceived change in bowel control (-5 to +5 where 0 is no change), overall satisfaction (0-10 visual analogue scale) and use of medications. A total of 166 patients underwent temporary nerve stimulation testing, of which 112 progressed to a permanent implantable pulse generator (IPG). Fifteen received an IPG without the testing phase, hence 127 patients in total. Fourteen had the IPG removed, four were deceased, leaving 109 for assessment; 91 (83%) responded to the survey. Mean follow-up was 2.7 years (range: 2 months-8.5 years). Mean baseline St Mark's continence score was 14.4, and mean follow-up score was 10.3 (P < 0.01). FIQL improved in all domains (P < 0.001). Patient-reported improved bowel control mean score was +3.2 (95% CI: 2.9, 3.55). Median satisfaction score was 8.0 (range: 0-10). Complications included 17 lead dislodgements, seven superficial infections, five infections requiring surgery and five repositioning of a rotated IPG. Thirty-two patients used loperamide and 34 used fibre supplements. In this observational study, limited by the absence of a placebo control group, SNS significantly improved continence and quality of life, and patient satisfaction was high. © 2016 Royal Australasian College of Surgeons.

  4. The stochastic Swift-Hohenberg equation

    Science.gov (United States)

    Gao, Peng

    2017-09-01

    In this paper, we will study the stochastic Swift-Hohenberg equation. The weak martingale solution, stationary martingale solution, invariant measures, mild solution, large deviation principle and random attractors for the stochastic Swift-Hohenberg equation will be considered.

  5. Treatment of rheumatoid arthritis with 90yttrium. Follow up studies

    International Nuclear Information System (INIS)

    Teuber, J.; Baenkler, H.W.; Regler, G.; Erlangen-Nuernberg Univ., Erlangen

    1978-01-01

    90 Yttrium-silicate was injected into 131 knee-joints from patients with rheumatoid arthritis with stadium II-IV according to Steinbrocker. The observation period lasted until two years. After three months about 80% and after 24 months still more than 50% of the patients treated showed complete or partial remission. Side-effects as formerly observed with 198 -goldpreparations did not occur. Therefore the treatment with 90 Yttrium-silicate offers an alternative to surgical synovectomy. (orig.) [de

  6. Barriers to follow-up for pediatric cataract surgery in Maharashtra, India: How regular follow-up is important for good outcome. The Miraj Pediatric Cataract Study II

    Directory of Open Access Journals (Sweden)

    Parikshit Gogate

    2014-01-01

    Full Text Available Background: Regular follow up and amblyopia treatment are essential for good outcomes after pediatric cataract surgery. Aim: To study the regularity of follow-up after cataract surgery in children and to gauge the causes of poor compliance to follow up. Subjects: 262 children (393 cataracts who underwent cataract surgery in 2004-8. Materials and Methods: The children were identified and examined in their homes and a "barriers to follow-up" questionnaire completed. Demographic data collected, visual acuity estimated, and ocular examination performed. Statistical Analysis: SPSS version 19. Results: Of the 262 children, only 53 (20.6% had been regularly following up with any hospital, 209 (79.4% had not. A total of 150 (57.3% were boys and the average age was 13.23 years (Std Dev 5 yrs. Poor follow up was associated with the older age group ( P 1 line with regular follow-up. Conclusion: Regular follow-up is important and improves vision; eye care practitioners need to take special efforts to ensure better follow-up.

  7. LOCALIZATION AND BROADBAND FOLLOW-UP OF THE GRAVITATIONAL-WAVE TRANSIENT GW150914

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, B. P.; Abbott, R.; Abernathy, M. R.; Adhikari, R. X. [LIGO, California Institute of Technology, Pasadena, CA 91125 (United States); Abbott, T. D. [Louisiana State University, Baton Rouge, LA 70803 (United States); Acernese, F.; Addesso, P. [Università di Salerno, Fisciano, I-84084 Salerno (Italy); Ackley, K. [University of Florida, Gainesville, FL 32611 (United States); Adams, C. [LIGO Livingston Observatory, Livingston, LA 70754 (United States); Adams, T. [Laboratoire d’Annecy-le-Vieux de Physique des Particules (LAPP), Université Savoie Mont Blanc, CNRS/IN2P3, F-74941 Annecy-le-Vieux (France); Adya, V. B.; Affeldt, C.; Allen, B. [Albert-Einstein-Institut, Max-Planck-Institut für Gravitationsphysik, D-30167 Hannover (Germany); Agathos, M.; Agatsuma, K. [Nikhef, Science Park, 1098 XG Amsterdam (Netherlands); Aggarwal, N. [LIGO, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Aguiar, O. D. [Instituto Nacional de Pesquisas Espaciais, 12227-010 São José dos Campos, SP (Brazil); Aiello, L. [INFN, Gran Sasso Science Institute, I-67100 L’Aquila (Italy); Ain, A. [Inter-University Centre for Astronomy and Astrophysics, Pune 411007 (India); Ajith, P., E-mail: lsc-spokesperson@ligo.org, E-mail: virgo-spokesperson@ego-gw.eu, E-mail: Julie.E.McEnery@nasa.gov [International Centre for Theoretical Sciences, Tata Institute of Fundamental Research, Bangalore 560012 (India); Collaboration: LIGO Scientific Collaboration and the Virgo Collaboration; Australian Square Kilometer Array Pathfinder (ASKAP) Collaboration; BOOTES Collaboration; Dark Energy Survey and the Dark Energy Camera GW-EM Collaborations; Fermi GBM Collaboration; Fermi LAT Collaboration; GRAvitational Wave Inaf TeAm (GRAWITA); INTEGRAL Collaboration; Intermediate Palomar Transient Factory (iPTF) Collaboration; InterPlanetary Network; J-GEM Collaboration; La Silla–QUEST Survey; Liverpool Telescope Collaboration; Low Frequency Array (LOFAR) Collaboration; MASTER Collaboration; MAXI Collaboration; Murchison Wide-field Array (MWA) Collaboration; Pan-STARRS Collaboration; PESSTO Collaboration; Pi of the Sky Collaboration; SkyMapper Collaboration; Swift Collaboration; TAROT, Zadko, Algerian National Observatory, and C2PU Collaboration; TOROS Collaboration; VISTA Collaboration; and others

    2016-07-20

    A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams.

  8. Optical follow-up of gravitational wave triggers with DECam

    Energy Technology Data Exchange (ETDEWEB)

    Herner, K.; Annis, J.; Berger, E.; Brout, D.; Butler, R.; Chen, H.; Cowperthwaite, P.; Diehl, H.; Doctor, Z.; Drlica-Wagner, A.; Farr, B.; Finley, D.; Frieman, J.; Holz, D.; Kessler, R.; Lin, H.; Marriner, J.; Nielsen, E.; Palmese, A.; Sako, M.; Soares-Santos, M.; Sobreira, F.; Yanny, B.

    2017-10-01

    Gravitational wave (GW) events have several possible progenitors, including black hole mergers, cosmic string cusps, supernovae, neutron star mergers, and black hole{neutron star mergers. A subset of GW events are expected to produce electromagnetic (EM) emission that, once detected, will provide complementary information about their astrophysical context. To that end, the LIGO-Virgo Collaboration has partnered with other teams to send GW candidate alerts so that searches for their EM counterparts can be pursued. One such partner is the Dark Energy Survey (DES) and Dark Energy Camera (DECam) Gravitational Waves Program (DES- GW). Situated on the 4m Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile, DECam is an ideal instrument for optical followup observations of GW triggers in the southern sky. The DES-GW program performs subtraction of new search images with respect to preexisting overlapping images to select candidate sources. Due to the short decay timescale of the expected EM counterparts and the need to quickly eliminate survey areas with no counterpart candidates, it is critical to complete the initial analysis of each night's images within 24 hours. The computational challenges in achieving this goal include maintaining robust I/O pipelines during the processing, being able to quickly acquire template images of new sky regions outside of the typical DES observing regions, and being able to rapidly provision additional batch computing resources with little advance notice. We will discuss the search area determination, imaging pipeline, general data transfer strategy, and methods to quickly increase the available amount of batch computing. We will present results from the rst season of observations from September 2015 to January 2016 and conclude by presenting improvements planned for the second observing season.

  9. Optical follow-up of gravitational wave triggers with DECam

    Science.gov (United States)

    Herner, K.; Annis, J.; Berger, E.; Brout, D.; Butler, R.; Chen, H.; Cowperthwaite, P.; Diehl, H.; Doctor, Z.; Drlica-Wagner, A.; Farr, B.; Finley, D.; Frieman, J.; Holz, D.; Kessler, R.; Lin, H.; Marriner, J.; Nielsen, E.; Palmese, A.; Sako, M.; Soares-Santos, M.; Sobreira, F.; Yanny, B.

    2017-10-01

    Gravitational wave (GW) events have several possible progenitors, including black hole mergers, cosmic string cusps, supernovae, neutron star mergers, and black hole–neutron star mergers. A subset of GW events are expected to produce electromagnetic (EM) emission that, once detected, will provide complementary information about their astrophysical context. To that end, the LIGO-Virgo Collaboration has partnered with other teams to send GW candidate alerts so that searches for their EM counterparts can be pursued. One such partner is the Dark Energy Survey (DES) and Dark Energy Camera (DECam) Gravitational Waves Program (DES-GW). Situated on the 4m Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile, DECam is an ideal instrument for optical followup observations of GW triggers in the southern sky. The DES-GW program performs subtraction of new search images with respect to preexisting overlapping images to select candidate sources. Due to the short decay timescale of the expected EM counterparts and the need to quickly eliminate survey areas with no counterpart candidates, it is critical to complete the initial analysis of each night’s images within 24 hours. The computational challenges in achieving this goal include maintaining robust I/O pipelines during the processing, being able to quickly acquire template images of new sky regions outside of the typical DES observing regions, and being able to rapidly provision additional batch computing resources with little advance notice. We will discuss the search area determination, imaging pipeline, general data transfer strategy, and methods to quickly increase the available amount of batch computing. We will present results from the first season of observations from September 2015 to January 2016 and conclude by presenting improvements planned for the second observing season.

  10. Control of Blood Pressure and Risk Attenuation: Post Trial Follow-Up of Randomized Groups.

    Directory of Open Access Journals (Sweden)

    Tazeen H Jafar

    Full Text Available Evidence on long term effectiveness of public health strategies for lowering blood pressure (BP is scarce. In the Control of Blood Pressure and Risk Attenuation (COBRA Trial, a 2 x 2 factorial, cluster randomized controlled trial, the combined home health education (HHE and trained general practitioner (GP intervention delivered over 2 years was more effective than no intervention (usual care in lowering systolic BP among adults with hypertension in urban Pakistan. However, it was not clear whether the effect would be sustained after the cessation of intervention. We conducted 7 years follow-up inclusive of 5 years of post intervention period of COBRA trial participants to assess the effectiveness of the interventions on BP during extended follow-up.A total of 1341 individuals 40 years or older with hypertension (systolic BP 140 mm Hg or greater, diastolic BP 90 mm Hg or greater, or already receiving treatment were followed by trained research staff masked to randomization status. BP was measured thrice with a calibrated automated device (Omron HEM-737 IntelliSense in the sitting position after 5 minutes of rest. BP measurements were repeated after two weeks. Generalized estimating equations (GEE were used to analyze the primary outcome of change in systolic BP from baseline to 7- year follow-up. The multivariable model was adjusted for clustering, age at baseline, sex, baseline systolic and diastolic BP, and presence of diabetes.After 7 years of follow-up, systolic BP levels among those randomised to combined HHE plus trained GP intervention were significantly lower (2.1 [4.1-0.1] mm Hg compared to those randomised to usual care, (P = 0.04. Participants receiving the combined intervention compared to usual care had a greater reduction in LDL-cholesterol (2.7 [4.8 to 0.6] mg/dl.The benefit in systolic BP reduction observed in the original cohort assigned to the combined intervention was attenuated but still evident at 7- year follow-up. These

  11. Availability of mobile phones for discharge follow-up of pediatric Emergency Department patients in western Kenya.

    Science.gov (United States)

    House, Darlene R; Cheptinga, Philip; Rusyniak, Daniel E

    2015-01-01

    Objective. Mobile phones have been successfully used for Emergency Department (ED) patient follow-up in developed countries. Mobile phones are widely available in developing countries and may offer a similar potential for follow-up and continued care of ED patients in low and middle-income countries. The goal of this study was to determine the percentage of families with mobile phones presenting to a pediatric ED in western Kenya and rate of response to a follow-up phone call after discharge. Methods. A prospective, cross-sectional observational study of children presenting to the emergency department of a government referral hospital in Eldoret, Kenya was performed. Documentation of mobile phone access, including phone number, was recorded. If families had access, consent was obtained and families were contacted 7 days after discharge for follow-up. Results. Of 788 families, 704 (89.3%) had mobile phone access. Of those families discharged from the ED, successful follow-up was made in 83.6% of cases. Conclusions. Mobile phones are an available technology for follow-up of patients discharged from a pediatric emergency department in resource-limited western Kenya.

  12. Long term follow-up of irradiated persons: rehabilitation process

    International Nuclear Information System (INIS)

    Bebeshko, V.; Kovalenko, A.; Belyi, D.

    1996-01-01

    In patients after acute radiation syndrome as result of Chernobyl accident a gradually forming of late radiation pathology was observed in following years. It is connected with destructive changes in the tissues with low proliferative activity. Among some of these patients a deviation of biochemical data and different clinical variants of dysplasia of haemopoiesis have been found. Taking in account the specialities of development and evolution of nonstochastic effects the system of rehabilitation and prophylactics has been developed and improved. This system was directed on the reduce of the late radiation pathology development and it's clinical manifestation. This system is characterized by the complex of different medical and rehabilitation measures

  13. Research and development of environment measuring laser radar. 6. Follow-up; Kankyo keisokuyo laser radar no kenkyu kaihatsu. 6. Follow up

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    In an effort to extend cooperation for reducing pollution in urban areas in the Asia-Pacific Region, a laser radar system was constructed in the city of Djakarta, Indonesia, in 1996, and a follow-up started in fiscal 1997. The aim is to collect information necessary for atmospheric environment improvement through observing pollutant distribution and movement in the upper atmospheric layers over the city. Mie-scattering lidar (laser infrared radar) observation has uninterruptedly been on since the summer of 1997, the system collecting data about Djakarta's atmospheric boundary structure throughout the year. The data indicate great changes in the atmospheric boundary structure between the dry and rainy seasons. The result of intensified observation conducted in the dry season shows that the altitude that the mixed layer reaches in the inland region is higher in the daytime and lower in the nighttime. It is necessary to compare the result with atmospheric pollution data collected on the ground surface and determine the relationship between the behavior of pollutants and the circulation of land-and-sea breeze. The data of September, 1997, reveal an aerosol layer at altitudes of 2km and higher, and this is attributed to forest fires. The result of intensified observation conducted in the dry season of 1998 is also stated. (NEDO)

  14. A follow-up investigation into the mechanisms that underlie improved recognition of dysarthric speech.

    Science.gov (United States)

    Borrie, Stephanie A; McAuliffe, Megan J; Liss, Julie M; O'Beirne, Greg A; Anderson, Tim J

    2012-08-01

    Differences in perceptual strategies for lexical segmentation of moderate hypokinetic dysarthric speech, apparently related to the conditions of the familiarization procedure, have been previously reported [Borrie et al., Language and Cognitive Processes (2012)]. The current follow-up investigation examined whether this difference was also observed when familiarization stimuli highlighted syllabic strength contrast cues. Forty listeners completed an identical transcription task following familiarization with dysarthric phrases presented under either passive or explicit learning conditions. Lexical boundary error patterns revealed that syllabic strength cues were exploited in both familiarization conditions. Comparisons with data previously reported afford further insight into perceptual learning of dysarthric speech.

  15. Presumed capillary telangiectasia of the pons: MRI and follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Kueker, W.; Thron, A. [Dept. of Neuroradiology, University Hospital of the Technical University, Aachen (Germany); Nacimiento, W.; Block, F. [Department of Neurology, University Hospital of the Technical University, Aachen (Germany)

    2000-06-01

    Capillary telangiectasia is a vascular abnormality primarily of the brainstem. The clinical relevance is unclear as is the association with clearly pathologic findings such as cavernous haemangioma. We report on four cases with capillary telangiectasia proven by follow-up und describe the imaging characteristics. T2 abnormality was only observed in half of the patients as was the presence of a discernable collecting vein. Whereas two cases were incidental findings in neurologically normal persons and one had symptoms clearly attributable to lacunar stroke, one patient may have had symptoms due to the vascular abnormality in the pons. (orig.)

  16. Olivary degeneration after intracranial haemorrhage or trauma: follow-up MRI

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, M.; Takashima, T.; Ueda, F.; Fujinaga, Y.; Horichi, Y. [Kanazawa Univ. (Japan). School of Medicine; Yamashita, J. [Department of Neurosurgery, Kanazawa Univ. (Japan)

    1999-01-01

    We studied serial MRI appearances of transneuronal degeneration in the inferior olives, retrospectively analysing follow-up images of five patients, three with head injury and two with brain stem haemorrhage. We performed 13 MRI studies 4 days to 2 years 7 months after the accident. All but one of the patients exhibited bilateral olivary high signal on T2-weighted images. The interval between causal event and appearance of olivary changes was 2-4 months, images 4 days to 1.5 months after the accidents revealing no changes. Olivary enlargement was observed in four patients 2-4 months after ictus. (orig.) (orig.) With 2 figs., 1 tab., 10 refs.

  17. Chernobyl disaster - promotion of the follow-up studies

    International Nuclear Information System (INIS)

    Romanenko, Anatoly; Bebeshko, Vladimir

    1997-01-01

    This paper analyses the problem of clinically observed effects of irradiation and other damaging agents of Chernobyl accident, in connection with previous data. Various international and national scientific programs were performed during the 10 years after the accident, and the obtained data are extremely useful for the elaboration of the system of radiation emergency medical preparedness and assistance network in Europe. Difficulties in diagnostic, therapeutical and statistical evaluation measures were characteristic for the first year after the accident. The paper recommends that future perspectives must include scientific investigation and practical help for the main groups of the irradiated population, on the international basis with the wide access to obtained data for the international community

  18. SWiFT Software Quality Assurance Plan.

    Energy Technology Data Exchange (ETDEWEB)

    Berg, Jonathan Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-01-01

    This document describes the software development practice areas and processes which contribute to the ability of SWiFT software developers to provide quality software. These processes are designed to satisfy the requirements set forth by the Sandia Software Quality Assurance Program (SSQAP). APPROVALS SWiFT Software Quality Assurance Plan (SAND2016-0765) approved by: Department Manager SWiFT Site Lead Dave Minster (6121) Date Jonathan White (6121) Date SWiFT Controls Engineer Jonathan Berg (6121) Date CHANGE HISTORY Issue Date Originator(s) Description A 2016/01/27 Jon Berg (06121) Initial release of the SWiFT Software Quality Assurance Plan

  19. Follow-up of hearing thresholds among forge hammering workers

    Energy Technology Data Exchange (ETDEWEB)

    Kamal, A.A.; Mikael, R.A.; Faris, R. (Ain Shams Univ., Abbasia, Cairo (Egypt))

    1989-01-01

    Hearing threshold was reexamined in a group of forge hammering workers investigated 8 years ago with consideration of the age effect and of auditory symptoms. Workers were exposed to impact noise that ranged from 112 to 139 dB(A)--at an irregular rate of 20 to 50 drop/minute--and a continuous background noise that ranged from 90 to 94 dB(A). Similar to what was observed 8 years ago, the present permanent threshold shift (PTS) showed a maximum notch at the frequency of 6 kHz and considerable elevations at the frequencies of 0.25-1 kHz. The age-corrected PTS and the postexposure hearing threshold were significantly higher than the corresponding previous values at the frequencies 0.25, 0.5, 1, and 8 kHz only. The rise was more evident at the low than at the high frequencies. Temporary threshold shift (TTS) values were significantly less than those 8 years ago. Contrary to the previous TTS, the present TTS were higher at low than at high frequencies. Although progression of PTS at the frequencies 0.25 and 0.5 kHz was continuous throughout the observed durations of exposure, progression at higher frequencies occurred essentially in the first 10 to 15 years of exposure. Thereafter, it followed a much slower rate. Tinnitus was significantly associated with difficulty in hearing the human voice and with elevation of PTS at all the tested frequencies, while acoustic after-image was significantly associated with increment of PTS at the frequencies 0.25-2 kHz. No relation between PTS and smoking was found. PTS at low frequencies may provide an indication of progression of hearing damage when the sensitivity at 6 and 4 kHz diminishes after prolonged years of exposure. Tinnitus and acoustic after-image are related to the auditory effect of forge hammering noise.

  20. Evaluating adherence to the Dutch guideline for diagnosis, treatment and follow-up of laryngeal carcinomas

    International Nuclear Information System (INIS)

    Agthoven, Michel van; Heule-Dieleman, Helene A.G.; Boer, Maarten F. de; Kaanders, Johannes H.A.M.; Baatenburg de Jong, Robert J.; Kremer, Bernd; Rene Leemans, C.; Marres, Henri A.M.; Manni, Johannes J.; Langendijk, Johannes A.; Levendag, Peter C.; Tjho-Heslinga, Reina E.; Jong, Joseph M.A. de; Uyl-de Groot, Carin A.; Knegt, Paul P.

    2005-01-01

    Background and purpose: An evidence-based clinical practice guideline for laryngeal carcinomas was introduced in the Netherlands late 1999. The objective of this guideline was to ensure uniformity in the diagnosis, treatment, and follow-up. We retrospectively evaluated whether clinical practice changed according to the recommendations of this guideline and whether it succeeded in its aim. Material and methods: In five out of eight Dutch university hospitals, chart data of 459 patients treated before the guideline introduction were compared to data of 363 patients treated after the guideline introduction. Results: Patient and tumour characteristics were comparable among both groups. In general, the guideline recommendations were properly complied with. The patients treated before the guideline introduction were actually also for a large part already treated according to the guideline's recommendations. After its introduction, several changes according to the guideline were observed: increased rates of reassessment of biopsy samples taken in local hospitals, psychological screening (although still only performed in 10.5% of patients), application of accelerated radiotherapy schedules, clinical trial treatments, function-preserving treatments, and decreased rates of total laryngectomy, and annual chest X-rays during follow-up. Conclusions: Although a causal relationship cannot be established in this kind of observational studies, several positive changes were observed after the introduction of the guideline, and therefore the guideline seems to have contributed to more uniformity. The largest changes were seen for the guideline recommendations based on the highest levels of evidence

  1. Prospects for Ground-Based Detection and Follow-up of TESS-Discovered Exoplanets

    Science.gov (United States)

    Varakian, Matthew; Deming, Drake

    2018-01-01

    The Transiting Exoplanet Survey Satellite (TESS) will monitor over 200,000 main sequence dwarf stars for exoplanetary transits, with the goal of discovering small planets orbiting stars that are bright enough for follow-up observations. We here evaluate the prospects for ground-based transit detection and follow-up of the TESS-discovered planets. We focus particularly on the TESS planets that only transit once during each 27.4 day TESS observing window per region, and we calculate to what extent ground-based recovery of additional transits will be possible. Using simulated exoplanet systems from Sullivan et al. and assuming the use of a 60-cm telescope at a high quality observing site, we project the S/N ratios for transits of such planets. We use Phoenix stellar models for stars with surface temperatures from 2500K to 12000K, and we account for limb darkening, red atmospheric noise, and missed transits due to the day-night cycle and poor weather.

  2. [The incidence of Frey syndrome following parotidectomy: results of a survey and follow-up].

    Science.gov (United States)

    Neumann, A; Rosenberger, D; Vorsprach, O; Dazert, S

    2011-02-01

    Frey's syndrome (FS) is defined as facial sweating due to gustatory stimuli following surgery or trauma of the parotid gland. Concomitant symptoms may occur in the area of the auriculotemporal nerve: swelling, facial flushing, and paresthesia. A misguided re-innervation of perspiratory glands by secretory parasympathetic fibres is likely responsible in the pathogenesis. The reported incidence in the literature varies considerably from 1.7% to 97.6%. The present study aims to clarify the incidence of FS. A questionnaire was sent to 221 consecutive patients who underwent parotidectomy between 07/2005 and 07/2008. No selection for type of parotidectomy or histological result was made. Patients were invited to undergo a follow-up examination including Minor's iodine starch test. A total of 135 of 221 (61%) questionnaires were available for evaluation. In all, 82 patients took part in the follow-up, with a follow-up period of 2.8 years (15-51 months). According to the questionnaire, 54% of patients claimed to be free of symptoms. Sweating following gustatory stimuli was reported by 23% of patients. Of the 82 Minor's tests performed, 62.2% were positive. All patients with subjective presence of FS had a positive Minor's test. In 27%, Minor's test was positive although patients did not suffer from facial sweating subjectively ("subclinical FS"). In all, 39% had no subjective complaints and Minor's test was also negative. Cases with a positive Minor's test showed no statistically significant relation to the patients' age, gender or to the histological diagnosis or type of parotidectomy. The clinical incidence of FS in our study is 23%, although a positive Minor's iodine starch test was observed in 62% of cases. Therefore, it seems justifiable to differentiate between a symptomatic or clinical FS and a merely asymptomatic or subclinical FS. No correlation was observed between epidemiological factors and the occurrence of FS. © Springer-Verlag 2010

  3. Long-term follow-up using testicle-sparing surgery for Leydig cell tumor.

    Science.gov (United States)

    Bozzini, Giorgio; Picozzi, Stefano; Gadda, Franco; Colombo, Renzo; Decobelli, Ottavio; Palou, Jean; Colpi, Giovannimaria; Carmignani, Luca

    2013-09-01

    Our objective was to perform a long-term evaluation of conservative surgical treatment of Leydig cell tumors. A multicenter retrospective clinical study was performed at 6 European centers. Case files of all patients diagnosed with Leydig cell tumor and treated with conservative surgery were examined. Patients underwent physical examination, hormone and tumor marker assays, scrotal and abdominal ultrasonography, chest radiography, and endocrinologic examination. From 1987 to 2006, 22 patients with Leydig cell tumor underwent conservative surgery. Mean patient age was 35 years (range, 5-61 years). Mean follow-up was 180 months (range, 77-290 months). No local recurrence or metastasis was observed. Patients presented with a palpable testicular nodule (3 patients [13.7%]), a nodule diagnosed by ultrasonography (15 patients [68.2%]), gynecomastia (2 patients [9.1%]), precocious pseudopuberty (1 patient [4.5%]), or scrotal pain (1 patient [4.5%]). Diagnosis after frozen section examination was Leydig cell tumor in 20 of 22 patients (91%). Mean histologic size of the nodule was 1.11 cm. Follow-up was conducted for all patients every 3 to 6 months, with physical examination, tumor marker assays, scrotal and abdominal ultrasonography, chest radiography, and computed tomography (CT). No local recurrences or metastases were observed. One hundred percent of patients are still alive with a 100% disease-free survival. When diagnosed and treated early, long-term favorable outcomes are seen at follow-up in Leydig cell tumors, even with its potential metastatic behavior. In these patients, testicle-sparing surgery proved to be a feasible and safe choice and could be regarded as the first line of therapy. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. Primary care follow-up of radical prostatectomy patients: A regional New Zealand experience

    Directory of Open Access Journals (Sweden)

    Omid Yassaie

    2016-12-01

    Conclusion: Our study identified that follow-up by GPs after RP is insufficient. Accordingly, there is a requirement for formal educational programs if primary care is to take a greater role in follow-up of these patients.

  5. Long-Term Follow-Up of Patients with Hypoparathyroidism

    Science.gov (United States)

    Mitchell, Deborah M.; Regan, Susan; Cooley, Michael R.; Lauter, Kelly B.; Vrla, Michael C.; Becker, Carolyn B.; Burnett-Bowie, Sherri-Ann M.

    2012-01-01

    Context: Despite tremendous interest in hypoparathyroidism, large cohort studies describing typical treatment patterns, laboratory parameters, and rates of complications are lacking. Objective: Our objective was to characterize the course of disease in a large cohort of hypoparathyroid patients. Design and Setting: We conducted a chart review of patients with permanent hypoparathyroidism identified via a clinical patient data registry. Patients were seen at a Boston tertiary-care hospital system between 1988 and 2009. Patients: We identified 120 patients. Diagnosis was confirmed by documented hypocalcemia with a simultaneous low or inappropriately normal PTH level for at least 1 yr. Mean age at the end of the observation period was 52 ± 19 (range 2–87) yr, and the cohort was 73% female. Main Outcome Measure: We evaluated serum and urine laboratory results and renal and brain imaging. Results: We calculated time-weighted average serum calcium measurements for all patients. The time-weighted average for calcium was between 7.5 and 9.5 mg/dl for the majority (88%) of patients. Using linear interpolation, we estimated the proportion of time within the target calcium range for each patient with a median of 86% (interquartile range 67–98%). Of those with a 24-h urine collection for calcium (n = 53), 38% had at least one measurement over 300 mg/d. Of those with renal imaging (n = 54), 31% had renal calcifications, and 52% of those with head imaging (n = 31) had basal ganglia calcifications. Rates of chronic kidney disease stage 3 or higher were 2- to 17-fold greater than age-appropriate norms. Conclusions: Hypoparathyroidism and its treatment carry a large burden of disease. Renal abnormalities are particularly common. PMID:23043192

  6. High-energy neutrino follow-up search of gravitational wave event GW150914 with ANTARES and IceCube

    NARCIS (Netherlands)

    Adrian-Martinez, S.; Albert, M.A.; Andre, M.; Anghinolfi, M.; Anton, G.; Ardid, M.; Aubert, J-J.; Avgitas, T.; Baret, B.; Barrios-Marti, J.; Basa, S.; Bertin, V.; Biagi, S.; Bormuth, R.; Bouwhuis, M. C.; Bruijn, J.R.; Brunner, J; Busto, J.A.A.; Capone, A.; Caramete, L.; Carr, J.; Celli, S.; Chiarusi, T.; Circella, M.; Coleiro, A.; Coniglione, R.; Costantini, H.; Coyle, P.K.; Creusot, A.; Deschamps, A.; De Bonis, G.; Distefano, C.; Donzaud, C.; Dornic, D.; Drouhin, D.; Eberl, T.; El Bojaddaini, I.; Elsaesser, D.; Enzenhoefer, A.; Fehn, K.; Felis, I.; Fusco, L. A.; Galata, S.; Gay, P.; Geisselsoeder, S.; Geyer, K.; Giordano, V.; Gleixner, A.; Glotin, H.; Gracia-Ruiz, R.; Graf, K.; Hallmann, S.; van Haren, H.; Heijboer, A. J.; Hello, Y.; Hernandez-Rey, J. J.; Hoessl, J.; Hofestaedt, J.; Hugon, C.; Illuminati, G.; James, C. W.; de Jong, M.; Jongen, E.M.M.; Kadler, M.; Kalekin, O.; Katz, U.; Kiessling, D.; Kouchner, A.; Kreter, M.; Kreykenbohm, I.; Kulikovskiy, V.; Lachaud, C.; Lahmann, R.; Lefevre, D.; Leonora, E.; Loucatos, S.; Marcelin, M.; Margiotta, A.; Marinelli, AW; Martinez-Mora, J. A.; Mathieu, A.; Melis, K.; Michael, T.; Migliozzi, P.; Moussa, A.; Mueller, C. L.; Nezri, E.; Pavalas, G. E.; Pellegrino, A.C.; Perrina, C.; Piattelli, P.; Popa, V.; Pradier, T.; Racca, C.; Riccobene, G.; Roensch, K.; Saldana, M.; Samtleben, D. F. E.; Sanchez-Losa, A.; Sanguineti, M.; Sapienza, P.; Schnabel, J.A.; Schuessler, F.; Seitz, T.; Sieger, C.; Spurio, M.; Stolarczyk, Th; Taiuti, M.; Trovato, A.; Tselengidou, M.; Turpin, D.; Toennis, C.; Vallage, B.; Vallee, C.; Van Elewyck, V.; Vivolo, D.; Wagner, S.; Wilms-Schopman, F.J.; Zornoza, J. D.; Zuniga, J.; Aartsen, M. G.; Abraham, K.; Ackermann, M; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Altmann, D.; Anderson, T.; Ansseau, I.; Anton, G.; Archinger, M.; Arguelles, C.; Arlen, T. C.; Auffenberg, J.; Bai, X.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Tjus, J. Becker; Becker, K-H.; Beiser, E.; BenZvi, S.; Berghaus, P.; Berley, D.; Bernardini, E.; Bernhard, A.; Besson, D. Z.; Binder, G.; Bindig, D.; Bissok, M.; Blaufuss, E.; Blumenthal, J.; Boersma, D.J.; Bohm, C.K.; Boerner, M.; Bos, M.F.; Bose, D.; Boeser, S.; Botner, O.; Braun, J.; Brayeur, L.; Bretz, H-P.; Buzinsky, N.; Casey, B.J.; Casier, M.; Cheung, E.; Chirkin, D.; Christov, A.; Clark, K.; Classen, L.; Coenders, S.; Collin, G. H.; Conrad, J. M.; Cowen, D. F.; Silva, A. H. Cruz; Daughhetee, J.; Davis, J.C.; Day, B.M.; de Andre, J. P. A. M.; le Clercq, C.M.C.; Rosendo, E. del Pino; Dembinski, H.; De Ridder, S.; Desiati, P.; de Vries, K. D.; de Wasseige, G.; de With, L.M.; DeYoung, T.; Diaz-Velez, J. C.; De Lorenzo, V.; Dujmovic, H.; Dumm, J. P.; Dunkman, M.; Eberhardt, B.; Ehrhardt, T.; Eichmann, B.; Euler, S.; Evenson, P. A.; Fahey, S.; Fazely, A. R.; Feintzeig, J.; Felde, J.; Filimonov, K.; Finley, C.; Flis, S.; Foesig, C-C.; Fuchs, T.; Gaisser, T. K.; Gaior, R.; Gallagher, J.; Gerhardt, L.M.S.; Ghorbani, K.; de Gier, L.; Gladstone, L.; Glagla, M.; Gluesenkamp, T.; Goldschmidt, A.; Golup, G.; Gonzalez-Macias, J.; Gora, D.; Grant, D.; Griffith, Z.; Ha, C.; Haack, C.; Ismail, A. Haj; Hallgren, A.; Halzen, F.; Hansen, B.E.; Hansmann, B.; Hansmann, T.; Hanson, K.; Hebecker, D.; Heereman, D.; Helbing, K.; Hellauer, R.; Hickford, S.; Hignight, J.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Holzapfel, K.; Homeier, A.; Hoshina, K.; Huang, F.; Huber, M.; Huelsnitz, W.; Hulth, P. O.; Hultqvist, K.; Schulte in den Baumen, T.; Ishihara, A.; Jacobi, C.E.; Japaridze, G. S.; Jeong, M.H.; Jero, K.; Jones, B. J. P.; Jurkovic, M.; Kappes, A.; Karg, T.; Karle, A.; Katz, U.; Kauer, M.; Keivani, A.; Kelley, J. L.; Kemp, J.; Kheirandish, A.; Kim, M.; Kintscher, T.; Kiryluk, J.; Klein, S. R.; Kohnen, G.; Koirala, R.; Kolanoski, H.; Konietz, R.; Koepke, L.; Kopper, C.; Kopper, S.; Koskinen, D. J.; Kowalski, M.L.; Krings, K.; Kroll, G.; Kroll, M.; Krueckl, G.; Kunnen, S.J.; Kunwar, S.; Kurahashi, N.; Kuwabara, T.; Labare, M.; Lanfranchi, J. L.; Larson, M. J.; Lennarz, D.; Lesiak-Bzdak, M.; Leuermann, M.; Leuner, J.; Lu, L.; Luenemann, J.D.; Madsen, J.; Maggi, G.; Mahn, K. B. M.; Mandelartz, M.; Maruyama, R.; Mase, K.; Matis, H. S.; Maunu, R.; McNally, F.; Meagher-Villemure, K.; Medici, M.; Meier, M.; Meli, A.; Menne, T.; Merino, G.; Meures, T.; Miarecki, S.; Middell, E.; Mohrmann, L.; Montaruli, T.; Morse, R.; Nahnhauer, R.; Naumann, U.; Neer, G.; Niederhausen, H.; Nowicki, S. C.; Nygren, D. R.; Pollmann, A. Obertacke; Olivas, A.; Omairat, A.; O'Murchadha, A.; Palczewski, T.; Pandya, H.; Pankova, D. V.; Paul, L.; Pepper, J. A.; de los Heros, C. Perez; Pfendner, C.; Pieloth, D.; Pinat, E.; Posselt, J.; Price, P. B.; Przybylski, G. T.; Quinnan, M.; Raab, C.; Raedel, L.; Rameez, M.; Rawlins, K.; Reimann, R.; Relich, M.; Resconi, E.; Rhode, W.; Richman, M.; Richter, S.; Riedel, B.; Robertson, S.; Rongen, M.; Rott, C.; Ruhe, T.; Ryckbosch, D.; Sabbatini, L.; Sander, H-G.; Sandrock, A.W.; Sandroos, J.; Sarkar, S.; Schatto, K.; Schimp, M.; Schlunder, P.; Schmidt, T.; Schoenen, S.; Schoeneberg, S.; Schoenwald, A.; Schumacher, L.; Seckel, D.; Seunarine, S.; Soldin, D.; Song, Michael; Spiczak, G. M.; Spiering, C.; Stahlberg, M.; Stamatikos, M.; Stanev, T.; Stasik, A.; Steuer, A.; Stezelberger, T.; Stokstad, R. G.; Stoessl, A.; Stroem, R.; Strotjohann, N. L.; Sullivan, G. W.; Sutherland, M.; Taavola, H.; Taboada, I.; Tatar, J.; Ter-Antonyan, S.; Terliuk, A.; Tesic, G.; Tilav, S.; Toale, P. A.; Tobin, M. N.; Toscano, S.; Tosi, D.; Tselengidou, M.; Turcati, A.; Unger, E.; Usner, M.; Vallecorsa, S.; Vandenbroucke, J.P.; van Eijndhoven, N.; Vanheule, S.; van Santen, J.; Veenkamp, J.; Vehring, M.; Voge, M.; Vraeghe, M.; Walck, C.; Wallace, A.M.; Wallraff, M.; Wandkowsky, N.; Weaver, Ch; Wendt, C.; Westerhoff, S.; Whelan, B. J.; Wiebe, K.; Wiebusch, C. H.; Wille, L.; Williams, D. R.; Wills, L.; Wissing, H.; Wolf, M.; Wood, T. R.; Woschnagg, K.; Xu, D. L.; Xu, X. W.; Xu, Y.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Zoll, M.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Phythian-Adams, A.T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.T.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, R.D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Belczynski, C.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, M.J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, A.L.S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, J.G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, T.C; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, A.D.; Brown, D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderon Bustillo, J.; Callister, T. A.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglia, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, D. S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Qian; Chua, S. E.; Chung, E.S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P. -F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M., Jr.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, A.C.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J. -P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, A.L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; Debra, D.; Debreczeni, G.; Degallaix, J.; De laurentis, M.; Deleglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.A.; DeRosa, R. T.; Rosa, R.; DeSalvo, R.; Dhurandhar, S.; Diaz, M. C.; Di Fiore, L.; Giovanni, M.G.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H. -B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, T. M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.M.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M; Fournier, J. -D.; Franco, S; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gatto, A.; Gaur, G.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.P.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; Gonzalez, Idelmis G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Lee-Gosselin, M.; Gouaty, R.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.M.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Buffoni-Hall, R.; Hall, E. D.; Hammond, G.L.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, P.J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C. -J.; Haughian, K.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J. -M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, D.H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jimenez-Forteza, F.; Johnson, W.; Jones, I.D.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, K.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.H.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kefelian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.E.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan., S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, C.; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Krishnan, B.; Krolak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C.H.; Lee, K.H.; Lee, M.H.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lueck, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magana-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandel, I.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Marka, S.; Marka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R.M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B.C.; Moore, J.C.; Moraru, D.; Gutierrez Moreno, M.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, S.D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P.G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Gutierrez-Neri, M.; Neunzert, A.; Newton-Howes, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J.; Oh, S. H.; Ohme, F.; Oliver, M. B.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ott, C. D.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.S; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perreca, A.; Phelps, M.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prix, R.; Prodi, G. A.; Prokhorov, L. G.; Puncken, O.; Punturo, M.; Puppo, P.; Puerrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, J. D.; Romano, R.; Romanov, G.; Romie, J. H.; Rosinska, D.; Rowan, S.; Ruediger, A.; Ruggi, P.; Ryan, K.A.; Sachdev, P.S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J; Schmidt, P.; Schnabel, R.B.; Schofield, R. M. S.; Schoenbeck, A.; Schreiber, K.E.C.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, M.S.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shah, S.; Shahriar, M. S.; Shaltev, M.; Shao, Z.M.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sigg, D.; Silva, António Dias da; Simakov, D.; Singer, A; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, R. J. E.; Smith, N.D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stone, J.R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S. E.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepanczyk, M. J.; Tacca, M.D.; Talukder, D.; Tanner, D. B.; Tapai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, W.R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Toeyrae, D.; Travasso, F.; Traylor, G.; Trifiro, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; Van Beuzekom, Martin; van den Brand, J. F. J.; Van Den Broeck, C.F.F.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasuth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P.J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Vicere, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J. -Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D. V.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, MT; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L. -W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.M.; Wessels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D. J.; Whiting, B. F.; Williams, D.R.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J.L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; Zadrozny, A.; Zangrando, L.; Zanolin, M.; Zendri, J. -P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.

    2016-01-01

    We present the high-energy-neutrino follow-up observations of the first gravitational wave transient GW150914 observed by the Advanced LIGO detectors on September 14, 2015. We search for coincident neutrino candidates within the data recorded by the IceCube and Antares neutrino detectors. A possible

  7. High-energy Neutrino follow-up search of Gravitational Wave Event GW150914 with ANTARES and IceCube

    NARCIS (Netherlands)

    Adrian-Martinez, S.; van Haren, H.; ANTARES Collaboration; IceCube Collaboration; Ligo Scientific Collaboration; Virgo Collaboration

    2016-01-01

    We present the high-energy-neutrino follow-up observations of the ?rst gravitational wave tran-sient GW150914 observed by the Advanced LIGO detectors on Sept. 14th, 2015. We search forcoincident neutrino candidates within the data recorded by the IceCube and Antares neutrino de-tectors. A possible

  8. Adherence to follow-up CT scans in patients with small pulmonary nodules, a retrospective study

    DEFF Research Database (Denmark)

    Johansson, Sofie Lock; Gerner Hansen, Niels-Christian

    2010-01-01

    was referred to another hospital and we have insufficient data on the follow-up. Another patient – also from 2008 -never came to the suggested first follow-up. Fifty eight patients have completed the first follow-up, while 10 are waiting for the first scheduled control CT. In twelve of the 19 patients (63...

  9. The impact of phone calls on follow-up rates in an online depression prevention study

    Directory of Open Access Journals (Sweden)

    R.F. Muñoz

    2017-06-01

    Conclusions: Adding phone call contacts to email reminders and monetary incentives did increase follow-up rates. However, the rate of response to follow-up was low and the number of phone calls required to achieve one completed follow-up raises concerns about the utility of adding phone calls. We also discuss difficulties with using financial incentives and their implications.

  10. 20 CFR 664.450 - What are follow-up services for youth?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What are follow-up services for youth? 664... YOUTH ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Youth Program Design, Elements, and Parameters § 664.450 What are follow-up services for youth? (a) Follow-up services for youth may include: (1...

  11. What is the value of the lateral chest radiograph in the follow-up thoracic lymphoma?

    International Nuclear Information System (INIS)

    Dobson, M.J.; Carrington, B.M.; Parsons, V.J.; Lo, F.; Coffey, J.; Ryder, W.D.J.; Collins, C.D.

    1997-01-01

    Lateral chest radiography in the investigation of thoracic lymphoma remains a feature of the current literature. This study assessed what information the lateral chest radiograph (CXR) adds in the follow-up of such patients. Eighty-eight patients with known lymphoma who had a CXR and thoracic CT within the same 4-week period were assessed. Five radiologists scored eight mediastinal and hilar nodal groups and eight extramediastinal regions on the frontal CXR as normal, equivocal or definitely abnormal (denoted 0, 1 and 2, respectively). This was repeated 1 week later with a combination of frontal and lateral films. Results were compared with the findings on CT which were scored similarly using accepted criteria for the presence of lymphadenopathy. Where the lateral CXR caused a change in score at any site, this change was compared with CT to determine the effect on diagnostic accuracy. For four of the five observers, the lateral film made no significant difference in diagnostic accuracy in the assessment of mediastinal lymph nodes. A fifth observer derived a small benefit from the addition of the lateral film, although almost 30 % of this was accounted for by changing from a wrong to an equivocal diagnosis. The lateral film did cause a small increase in the detection of pleuro-parenchymal lung lesions, although none of these were clinically significant. We conclude that routine lateral chest radiography is unhelpful in the follow-up of patients with lymphoma. (orig.). With 4 tabs

  12. Overweight and musculoskeletal morbidity: a ten-year follow-up.

    Science.gov (United States)

    Aro, S; Leino, P

    1985-01-01

    The association of relative weight with various indices of musculoskeletal morbidity was studied in 902 Finnish white-collar and blue-collar workers. Data were collected in the years 1973 and 1983 through a postal questionnaire, by medical examination, and clinical assessment of the condition of the musculoskeletal system. In the overweight group (relative weight greater than or equal to 120 percent), higher mean levels in all musculoskeletal scores (the Musculoskeletal Symptoms Score, the Upper/Lower Extremities Score, the Low Back Score and the Musculoskeletal Findings Score) were observed, compared with the normal weight group. There was no evidence, however of rheumatic complaints in weight-bearing joints being more common in overweight individuals, contrary to the 'wear and tear' hypothesis. In a 10-year follow-up the changes in the musculoskeletal scores were analysed by stepwise multiple regression. Baseline relative weight explained 6.3 percent of the variation in the score based on clinical assessment. Neither baseline weight nor weight change were significant predictors of change in the other scores. No association was observed between overweight and lumbosacral disorders either in the cross-sectional study or in the 10-year follow-up.

  13. Surgical Treatment of Peri-Implantitis: A 17-Year Follow-Up Clinical Case Report

    Directory of Open Access Journals (Sweden)

    Fabrizio Bassi

    2015-01-01

    Full Text Available The purpose of the present case report was to describe the surgical treatment of a peri-implantitis lesion associated with a regenerative approach. A 48-year-old patient came to authors’ attention 36 months after the placement of a dental implant (ITI-Bonefit Straumann, Waldenburg, Switzerland in position 46. A swelling of the peri-implant soft tissues was observed, associated with bleeding on probing and probing depth > 10 mm. A significant peri-implant bone loss was clearly visible on the periapical radiograph. A nonsurgical periodontal supportive therapy was firstly conducted to reduce the inflammation, followed by the surgical treatment of the defect. After mechanical and chemical decontamination with tetracycline solution, a regenerative approach consisting in the application of deproteinized bovine bone mineral (Bio-Oss, Geistlich Pharma AG, Wolhusen, Switzerland and a collagen membrane (Bio-Gide, Geistlich Pharma AG, Wolhusen, Switzerland was performed. An antibiotic therapy was associated with the treatment. The 17-year follow-up showed a physiological probing depth with no clinical signs of peri-implant inflammation and bleeding on probing. No further radiographic bone loss was observed. The treatment described in the present case report seemed to show improved clinical results up to a relevant follow-up period.

  14. Learning, Memory, and Executive Function in New MDMA Users: A 2-Year Follow-Up Study.

    Science.gov (United States)

    Wagner, Daniel; Tkotz, Simon; Koester, Philip; Becker, Benjamin; Gouzoulis-Mayfrank, Euphrosyne; Daumann, Joerg

    2015-01-01

    3,4-Methylenedioxymethamphetamine (MDMA) is associated with changes in neurocognitive performance. Recent studies in laboratory animals have provided additional support for the neurodegeneration hypothesis. However, results from animal research need to be applied to humans with caution. Moreover, several of the studies that examine MDMA users suffer from methodological shortcomings. Therefore, a prospective cohort study was designed in order to overcome these previous methodological shortcomings and to assess the relationship between the continuing use of MDMA and cognitive performance in incipient MDMA users. It was hypothesized that, depending on the amount of MDMA taken, the continued use of MDMA over a 2-year period would lead to further decreases in cognitive performance, especially in visual paired association learning tasks. Ninety-six subjects were assessed, at the second follow-up assessment: 31 of these were non-users, 55 moderate-users, and 10 heavy-users. Separate repeated measures analyses of variance were conducted for each cognitive domain, including attention and information processing speed, episodic memory, and executive functioning. Furthermore, possible confounders including age, general intelligence, cannabis use, alcohol use, use of other concomitant substances, recent medical treatment, participation in sports, level of nutrition, sleep patterns, and subjective well-being were assessed. The Repeated measures analysis of variance (rANOVA) revealed that a marginally significant change in immediate and delayed recall test performances of visual paired associates learning had taken place within the follow-up period of 2 years. No further deterioration in continuing MDMA-users was observed in the second follow-up period. No significant differences with the other neuropsychological tests were noted. It seems that MDMA use can impair visual paired associates learning in new users. However, the groups differed in their use of concomitant use of

  15. Granulomatous colitis: findings on double contrast barium enema and follow-up studies

    International Nuclear Information System (INIS)

    Song, Jong Gi; Han, Joon Koo; Kim, Seung Hoon; Choo, Sung Wook; Kim, Seung Cheol; Choi, Byung Ihn

    1995-01-01

    To evaluate the radiologic findings of granulomatous colitis on double contrast barium enema and changes on follow-up studies. Serial double contrast barium enema of six patients with granulomatous colitis confirmed by endoscopic biopsy were reviewed. We analyzed the radiologic findings and their follow-up changes, including aphthous ulcers, lymphoid hyperplasia, deep ulcers, cobble stone appearance, geographic ulcers, asymmetric involvement of ulcers, skip lesions, sinus tract, fistula formation, pseudosacculation, focal stricture, and small bowel involvement. Pretreatment double contrast barium enema findings were aphthous ulcers in five patients, deep ulcer in six, cobble stone appearance in five, longitudinal geographic ulcers in two, fistulas in one, pseudosacculations in two, focal stricture in one, and pseudopolyps in six. Also, anal ulcers were observed in two patients, asymmetric involvement of ulcers in three, skip lesions in four, and small bowel involvement in five in five patients proved to have inactive disease after treatment, aphthous ulcers and deep ulcers disappeared. Geographic ulcers of two patients and anal ulcer of one patients decreased in size or depth. Pseudosacculation in one patient disappeared. Pseudopolyps decreased in two patients, increased in one, and decreased after increase in two. One patient whose disease remained active after treatment showed maintenance or increase of ulcers or fistula. And their pseudosacculation or focal stricture unchanged and pseudopolyps decreased. The major radiologic findings of chronic granulomatous colitis on double contrast barium enema are aphthous ulcer, deep ulcer, cobble stone appearance, discontinuity of the lesion and coexistence of ulcers and pseudopolyps. And, double contrast barium enema is good follow-up modality because its findings correlate with clinical course of the granulomatous colitis after treatment

  16. Longterm follow-up of small pancreatic cystic lesions in liver transplant recipients.

    Science.gov (United States)

    Vidhyarkorn, Sirachat; Siripongsakun, Surachate; Yu, Jennifer; Sayre, James; Agopian, Vatche G; Durazo, Francisco; Lu, David S

    2017-03-01

    Incidental small pancreatic cystic lesions (PCLs) are often found on preoperative imaging in patients undergoing orthotopic liver transplantation (OLT). Although these are considered benign or of low malignant potential, the influence of immunosuppression after OLT may be of concern. The aim of this study was to observe the longterm outcome of these small PCLs in post-OLT patients. An institutional OLT database of 1778 consecutive OLT patients from January 2000 to December 2010 was analyzed. Computed tomography, magnetic resonance imaging, or endoscopic ultrasound at the time of OLT and all subsequent imaging, cytology, fluid analysis of PCLs, and patient status were evaluated. A total of 70 patients with 182 PCLs, of benign or low malignant potential, were identified with a mean follow-up time of 64 months. At initial diagnosis of PCLs in 48 patients, 7 branch duct-type intraductal papillary mucinous neoplasms (B-IPMNs), 1 serous cystadenoma (SCA), and 40 nonspecific benign cysts were identified. Final diagnosis at the end of the follow-up revealed 16 B-IPMNs, 3 SCAs, and a mixed acinar-neuroendocrine carcinoma, in which the latter developed 9 years after initial diagnosis of B-IPMN. During the follow-up time, average increase in size and number of PCLs were 4.5 mm and 1.4, respectively (P < 0.001 for both). The majority of incidental PCLs in OLT patients showed an indolent behavior despite immunosuppression. Risk of malignancy development was very low and comparable with normal population. Liver Transplantation 23 324-329 2017 AASLD. © 2016 by the American Association for the Study of Liver Diseases.

  17. The efficacy and safety of bronchial thermoplasty in severe persistent asthma on extended follow-up.

    Science.gov (United States)

    O'Reilly, A; Browne, I; Watchorn, D; Egan, J J; Lane, S

    2018-03-01

    Asthma is a common condition and there remains a subset of patients who are poorly controlled on maximal therapy. Bronchial thermoplasty (BT) is a bronchoscopic therapy using radiofrequency energy to reduce airway smooth muscle, which has been shown to improve asthma control although further evidence regarding long-term efficacy and safety is required. We aimed to demonstrate safety and efficacy of BT on extended follow-up. Our initial experience with this group was previously reported in 2016, where patients were shown to have a significant improvement in asthma control test (ACT) scores 1-year post-treatment. We carried out a retrospective observational study of seven patients who underwent BT between 2012 and 2013 in an Irish severe asthma centre. The primary endpoint was change in ACT scores from baseline to present. Seven patients underwent BT at a tertiary referral centre in Ireland. ACT scores and data on hospital admissions, exacerbations, maintenance corticosteroid requirements, rescue bronchodilator use and forced expiratory volume for 1 s (FEV1) prior to the procedure and on extended follow-up were collected. Mean follow-up was 49.42 months. A trend towards improvement was seen in median hospitalisations (respective values for median over 12 months 3, 1 P = 0.059) and ACT scores, from 9 to 13 (P = 0.249). Mean FEV1 was 1.68 l prior to treatment and 1.46 l 4 years post-treatment (P = 0.237). There was no mortality among the group. These data support the safety of BT and suggest extended efficacy. © The Author 2017. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  18. Sacral-Alar-Iliac Fixation in Children with Neuromuscular Scoliosis: Minimum 5-Year Follow-Up.

    Science.gov (United States)

    Jain, Amit; Sullivan, Brian T; Kuwabara, Anne; Kebaish, Khaled M; Sponseller, Paul D

    2017-12-01

    To investigate the 5-year outcomes of children with neuromuscular scoliosis treated with sacral-alar-iliac screws. We reviewed clinical and radiographic records of patients aged ≤18 years treated by 1 pediatric orthopedic surgeon for neuromuscular scoliosis with spinal fusion using sacral-alar-iliac pelvic anchors. Thirty-eight patients with a minimum 5-year radiographic follow-up (mean, 6.0 ± 1.2 years) were studied. The mean patient age was 13 ± 2.0 years, and 47% were female. The mean number of levels fused was 18 ± 0.7. Two-thirds (66%) of the patients were diagnosed with cerebral palsy. Between the preoperative period and final follow-up, the patients exhibited a mean correction of the major coronal curve of 79% (preoperative, 85° to final, 18°) and a mean 57% correction of the pelvic obliquity (preoperative, 16° to final, 7°). Patients maintained the correction of mean pelvic obliquity from the early postoperative period (6°) to final follow-up (7°). Preoperatively, 76% of the patients had a pelvic obliquity of >10°, compared with 26% of patients postoperatively. There were no cases of neurologic or vascular complications or pseudarthrosis. Radiographs revealed bilateral sacral-alar-iliac screw lucency in 8 patients; 4 of these patients had deep wound infections, and the other 4 were asymptomatic. Unilateral screw fracture was found in 1 patient with an 8-mm-diameter screw (1.3%; 1 of 76 screws); the patient was observed and remained asymptomatic. There were no cases of set screw displacement, screw back-out, or rod dislodgement. Sacral-alar-iliac screws are safe and effective pelvic anchors for use in children with neuromuscular scoliosis. Copyright © 2017. Published by Elsevier Inc.

  19. [Transpedicular dynamics stabilization in the treatment of lumbar stenosis. Fourth years follow-up].

    Science.gov (United States)

    Reyes-Sánchez, Alejandro; Sánchez-Bringas, Guadalupe; Zarate-Kalfopulos, Barón; Alpizar-Aguirre, Armando; Lara-Padilla, Eleazar; Rosales-Olivares, Luis Miguel

    2013-01-01

    We need to evaluate the efficacy and safety of the use of dynamic fixation in patients with narrow lumbar through comparing the assessment of two years with 4 years of follow-up. Prospective, longitudinal, autocontrol deliberately and sequential intervention, in lumbar stenosis patients who made treatment with dynamic stabilization posterior type Acuflex. An evaluation of four of final follow-up. 18 patients who completed follow-up two years results as a basis for comparison: 18 patients, 14 female and 4 male, average age 44.05 years. Pain evaluated with numerical visual scale was found in the lower back at 24 months in an average of 2.84 and 48 months in 3.26. We measured the functional level of Oswestry at two years to be 24% and at four years 22.44%, with a p = 0.373. In the magnetic resonance for classification of patients 15 Pfirrmann without changes and three with increase of a degree. According to patients 2 Modic changes one of type 0 to type III and another to type I. We have observed that five patients have required second surgery for removal of material findings. There is no change between 2 and 4 years in the scale of Oswestry and pain with visual numerical scale functionality. The average height in discs had change with statistical significance, in the comparative period. The intervertebral discs had changes in 3 patients with direct relationship between scale of Pfirrmann and Modic. The rest of patients keep rehydration and normal disc height.

  20. Antipsychotic use in children and adolescents: a 1-year follow-up study.

    Science.gov (United States)

    Baeza, Inmaculada; de la Serna, Elena; Calvo-Escalona, Rosa; Morer, Astrid; Merchán-Naranjo, Jessica; Tapia, Cecilia; Martínez-Cantarero, Ma Carmen; Andrés, Patrícia; Alda, José A; Sánchez, Bernardo; Arango, Celso; Castro-Fornieles, Josefina

    2014-10-01

    The objective of this study was to analyze the initial treatment with antipsychotics (APs) and its changes during the first year of treatment in patients visited in specialized child and adolescent psychiatry departments. Participants were 265 patients, aged 4 to 17 years, who attended consecutively at 4 different centers and were naive of AP or quasi-naive (less than 30 days since the beginning of AP treatment). Type of AP, dosage, and concomitant medication were registered at baseline, 1, 3, 6, and 12 months after beginning the treatment with AP. At baseline, the patients' mean age was 14.4 (2.9) years, and 145 (54.7%) patients were males. Antipsychotics were more prescribed in the following: schizophrenia spectrum disorders (30.2%), disruptive behavior disorders (DBDs) (18.9%), bipolar disorders (14.3%), depressive disorders (12.8%), and eating disorders (11.7%). A total of 93.2% of the patients were on an off-label indication of AP. Risperidone was the AP most prescribed in all the assessments, but differences were observed in the type of AP according to diagnosis. Thus, risperidone was significantly most prescribed in patients with DBD and olanzapine was most prescribed in patients with eating disorders. Olanzapine and quetiapine were the second-generation APs (SGAs) most prescribed after risperidone, and haloperidol was the most prescribed first-generation AP. Up to 8.3% of patients during the follow-up were on AP polypharmacy. Almost 16% patients had a change in its AP treatment during the follow-up, and the main switch was from one SGA to another. Second-generation APs were the APs most prescribed in our sample and approximately 93% of the patients used AP off-label. Risperidone was the most common AP used above all in patients with DBD, whereas olanzapine was most prescribed in patients with eating disorders. Antipsychotic polypharmacy and switch rates were low during the follow-up.

  1. Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Anselmetti, Giovanni Carlo, E-mail: gc.anselmetti@fastwebnet.it [Villa Maria Hospital, Interventional Radiology Unit (Italy); Manca, Antonio, E-mail: anto.manca@gmail.com [Institute for Cancer Research and Treatment (IRCC), Interventional Radiology Unit (Italy); Marcia, Stefano, E-mail: stemarcia@gmail.com [Institute of Radiology, University of Cagliari (Italy); Chiara, Gabriele, E-mail: gabriele.chiara@ircc.it [Institute for Cancer Research and Treatment (IRCC), Interventional Radiology Unit (Italy); Marini, Stefano, E-mail: stemarini@gmail.com [Institute of Radiology, University of Cagliari (Italy); Baroud, Gamal, E-mail: gamalbaroud@gmail.com [University of Sherbrooke, Departement de Genie Mecanique (Canada); Regge, Daniele, E-mail: daniele.regge@ircc.it [Institute for Cancer Research and Treatment (IRCC), Radiology Unit (Italy); Montemurro, Filippo, E-mail: filippo.montemurro@ircc.it [Institute for Cancer Research and Treatment (IRCC), Internal Medicine Unit (Italy)

    2013-05-08

    PurposeThis study was designed to assess the clinical outcomes of patients treated by vertebral augmentation with nitinol endoprosthesis (VNE) to treat painful vertebral compression fractures.MethodsForty patients with one or more painful osteoporotic VCF, confirmed by MRI and accompanied by back-pain unresponsive to a minimum 2 months of conservative medical treatment, underwent VNE at 42 levels. Preoperative and postoperative pain measured with Visual Analog Scale (VAS), disability measured by Oswestry Disability Index (ODI), and vertebral height restoration (measured with 2-dimensional reconstruction CT) were compared at last follow-up (average follow-up 15 months). Cement extravasation, subsequent fractures, and implant migration were recorded.ResultsLong-term follow-up was obtained in 38 of 40 patients. Both VAS and ODI significantly improved from a median of 8.0 (range 5–10) and 66 % (range 44–88 %) to 0.5 (range 0–8) and 6 % (range 6–66 %), respectively, at 1 year (p < 0.0001). Vertebral height measurements comparing time points increased in a statistically significant manner (ANOVA, p < 0.001). Overall cement extravasation rate was 9.5 %. Discal and venous leakage rates were 7.1 and 0 % respectively. No symptomatic extravasations occurred. Five of 38 (13.1 %) patients experienced new spontaneous, osteoporotic fractures. No device change or migration was observed.ConclusionsVNE is a safe and effective procedure that is able to provide long-lasting pain relief and durable vertebral height gain with a low rate of new fractures and cement leakages.

  2. Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up

    International Nuclear Information System (INIS)

    Anselmetti, Giovanni Carlo; Manca, Antonio; Marcia, Stefano; Chiara, Gabriele; Marini, Stefano; Baroud, Gamal; Regge, Daniele; Montemurro, Filippo

    2014-01-01

    PurposeThis study was designed to assess the clinical outcomes of patients treated by vertebral augmentation with nitinol endoprosthesis (VNE) to treat painful vertebral compression fractures.MethodsForty patients with one or more painful osteoporotic VCF, confirmed by MRI and accompanied by back-pain unresponsive to a minimum 2 months of conservative medical treatment, underwent VNE at 42 levels. Preoperative and postoperative pain measured with Visual Analog Scale (VAS), disability measured by Oswestry Disability Index (ODI), and vertebral height restoration (measured with 2-dimensional reconstruction CT) were compared at last follow-up (average follow-up 15 months). Cement extravasation, subsequent fractures, and implant migration were recorded.ResultsLong-term follow-up was obtained in 38 of 40 patients. Both VAS and ODI significantly improved from a median of 8.0 (range 5–10) and 66 % (range 44–88 %) to 0.5 (range 0–8) and 6 % (range 6–66 %), respectively, at 1 year (p < 0.0001). Vertebral height measurements comparing time points increased in a statistically significant manner (ANOVA, p < 0.001). Overall cement extravasation rate was 9.5 %. Discal and venous leakage rates were 7.1 and 0 % respectively. No symptomatic extravasations occurred. Five of 38 (13.1 %) patients experienced new spontaneous, osteoporotic fractures. No device change or migration was observed.ConclusionsVNE is a safe and effective procedure that is able to provide long-lasting pain relief and durable vertebral height gain with a low rate of new fractures and cement leakages

  3. Interstitial lung disease in anti-synthetase syndrome: Initial and follow-up CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Debray, Marie-Pierre, E-mail: marie-pierre.debray@bch.aphp.fr [AP-HP, Bichat-Claude Bernard Hospital, Department of Radiology, 46, rue Henri Huchard, 75877 Paris Cedex 18 (France); Borie, Raphael, E-mail: raphael.borie@bch.aphp.fr [AP-HP, Bichat-Claude Bernard Hospital, Department of Pneumology A and Centre de Compétence Maladies Pulmonaires rares, DHU Fire 46, rue Henri Huchard, 75877 Paris Cedex 18 (France); Inserm, U1152, Paris (France); Revel, Marie-Pierre, E-mail: marie-pierre.revel@htd.aphp.fr [AP-HP, Cochin Hospital, Department of Radiology, 27, Rue du Fg Saint Jacques, 75679 Paris Cedex 14 (France); Naccache, Jean-Marc, E-mail: jean-marc.naccache@tnn.aphp.fr [AP-HP, Avicenne Hospital, Department of Pneumology and Centre de Compétence Maladies Pulmonaires rares, Bobigny (France); AP-HP, Tenon Hospital, Department of Pneumology and Centre de Compétence Maladies Pulmonaires rares, 4, rue de la Chine, 75020 Paris (France); Khalil, Antoine, E-mail: antoine.khalil@tnn.aphp.fr [AP-HP, Tenon Hospital, Department of Radiology, 4, rue de la Chine, 75020 Paris (France); Toper, Cécile, E-mail: cecile.toper@gmail.com [AP-HP, Tenon Hospital, Department of Pneumology and Centre de Compétence Maladies Pulmonaires rares, 4, rue de la Chine, 75020 Paris (France); Israel-Biet, Dominique, E-mail: dominique.israel-biet@egp.aphp.fr [Université Paris Descartes and AP-HP, Department of Pneumology, Georges Pompidou European Hospital, 20, rue Leblanc, 75015 Paris (France); and others

    2015-03-15

    Purpose: To describe the initial and follow-up CT features of interstitial lung disease associated with anti-synthetase syndrome (AS-ILD). Materials and methods: Two independent thoracic radiologists retrospectively analysed thin-section CT images obtained at diagnosis of AS-ILD in 33 patients (17 positive for anti-Jo1, 13 for anti-PL12, and three for anti-PL7 antibodies). They evaluated the pattern, distribution and extent of the CT abnormalities. They also evaluated the change in findings during follow-up (median 27 months; range 13–167 months) in 26 patients. Results: At diagnosis, ground-glass opacities (100%), reticulations (87%) and traction bronchiectasis (76%) were the most common CT findings. Consolidations were present in 45% of patients. A non-specific interstitial pneumonia (NSIP), organizing pneumonia (OP) or mixed NSIP-OP CT pattern were observed in 15 out of 33 (45%), seven out of 33 (21%) and eight out of 33 (24%) patients, respectively, whereas the CT pattern was indeterminate in three patients. During follow-up, consolidations decreased or disappeared in 11 out of 12 patients (92%), among which seven within the first 6 months, but honeycombing progressed or appeared in ten out of 26 patients (38%) and overall disease extent increased in nine out of 26 patients (35%). Conclusion: CT features at diagnosis of AS-ILD mainly suggest NSIP and OP, isolated or in combination. Consolidations decrease or disappear in most cases but the disease may progress to fibrosis in more than one third of patients.

  4. Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up

    Directory of Open Access Journals (Sweden)

    Reza Mohammadian

    2013-01-01

    Full Text Available Background. Intracranial artery dissections are rare and many controversies exist about treatment options. The aim of this study was to evaluate the efficacy and safety of the endovascular approach in patients with an intracranial dissection presenting with different symptoms. Methods. We prospectively evaluated the clinical features and treatment outcomes of 30 patients who had angiographically confirmed nontraumatic intracranial dissections over 4 years. Patients were followed up for 17 months, and their final outcomes were assessed by the modified Rankin Score (mRS and angiography. Results. Sixteen (53.3% patients had a dissection of the anterior circulation, whereas 14 (46.7% had a posterior circulation dissection. Overall, 83.3% of the patients suffered a subarachnoid hemorrhage (SAH. Grade IV Hunt and Hess score was seen in 32% of the SAH presenting cases. Parent artery occlusion (PAO with coil embolization was used in 70% of the cases. The prevalence of overall procedural complications was 23.3%, and all were completely resolved at the end of follow-up. No evidence of in-stent occlusion/stenosis or rebleeding was observed in our cases during follow-up. Angiography results improved more frequently in the PAO with coil embolization group (100% than in the stent-only-treated group (88.9% (P=0.310 and the unruptured dissection group (5/5, 100% in comparison with the group that presented with SAH (95.8% (P=0.833. Conclusion. Favorable outcomes were achieved following an endovascular approach for symptomatic ruptured or unruptured dissecting aneurysms. However, the long-term efficacy and durability of these procedures remain to be determined in a larger series.

  5. Discovery, Follow-up, and Implications of the Optical/Infrared Counterpart to GW170817

    Science.gov (United States)

    Drout, Maria

    2018-01-01

    On August 17th, 2017, the field of multi-messenger, gravitational-wave, astronomy was born. On this date, Advanced LIGO and Advanced Virgo observed gravitational waves from the coalescence of a neutron star binary with a false alarm probability of 1 per 10000 years and electromagnetic counterparts were subsequently identified across the entire electromagnetic spectrum. In this talk, I will give a broad review of the optical and infrared emission associated with the binary neutron star merger, GW170817. I will describe the process of the discovery and localization of the optical counterpart, and review the extensive follow-up observations obtained over the following three weeks. Finally, I will place these results in context. I will discuss the implications of these observations on our understanding of the ejecta from neutron star mergers, the origin of r-process elements, and the prospects for the identification of similar transients in upcoming surveys.

  6. Patient responses to research recruitment and follow-up surveys: findings from a diverse multicultural health care setting in Qatar

    Directory of Open Access Journals (Sweden)

    Amal Khidir

    2016-01-01

    often from the persons’ own culture—recruited face-to-face, and our questionnaire contained no health care-related content, many persons were reluctant to participate. This occurrence was observed especially at follow-up, particularly among participants who had agreed to follow-up by post.

  7. Correcting Mortality for Loss to Follow-Up: A Nomogram Applied to Antiretroviral Treatment Programmes in Sub-Saharan Africa

    Science.gov (United States)

    Egger, Matthias; Spycher, Ben D.; Sidle, John; Weigel, Ralf; Geng, Elvin H.; Fox, Matthew P.; MacPhail, Patrick; van Cutsem, Gilles; Messou, Eugène; Wood, Robin; Nash, Denis; Pascoe, Margaret; Dickinson, Diana; Etard, Jean-François; McIntyre, James A.; Brinkhof, Martin W. G.

    2011-01-01

    Background The World Health Organization estimates that in sub-Saharan Africa about 4 million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008. Loss of patients to follow-up and care is an important problem for treatment programmes in this region. As mortality is high in these patients compared to patients remaining in care, ART programmes with high rates of loss to follow-up may substantially underestimate mortality of all patients starting ART. Methods and Findings We developed a nomogram to correct mortality estimates for loss to follow-up, based on the fact that mortality of all patients starting ART in a treatment programme is a weighted average of mortality among patients lost to follow-up and patients remaining in care. The nomogram gives a correction factor based on the percentage of patients lost to follow-up at a given point in time, and the estimated ratio of mortality between patients lost and not lost to follow-up. The mortality observed among patients retained in care is then multiplied by the correction factor to obtain an estimate of programme-level mortality that takes all deaths into account. A web calculator directly calculates the corrected, programme-level mortality with 95% confidence intervals (CIs). We applied the method to 11 ART programmes in sub-Saharan Africa. Patients retained in care had a mortality at 1 year of 1.4% to 12.0%; loss to follow-up ranged from 2.8% to 28.7%; and the correction factor from 1.2 to 8.0. The absolute difference between uncorrected and corrected mortality at 1 year ranged from 1.6% to 9.8%, and was above 5% in four programmes. The largest difference in mortality was in a programme with 28.7% of patients lost to follow-up at 1 year. Conclusions The amount of bias in mortality estimates can be large in ART programmes with substantial loss to follow-up. Programmes should routinely report mortality among patients retained in care and the proportion of patients lost. A simple

  8. Patients highly value routine follow-up of skin cancer and cutaneous melanoma

    DEFF Research Database (Denmark)

    Themstrup, Lotte; Jemec, Gregor E; Lock-Andersen, Jørgen

    2013-01-01

    : This study included an open sample of patients attending routine follow-up at the outpatient Departments of Plastic Surgery and Dermatology, Roskilde Hospital. A total of 218 follow-up patients diagnosed with cutaneous malignant melanoma (MM), non-melanoma skin cancer (NMSC) or actinic keratosis (AK......INTRODUCTION: Skin cancer follow-up is a substantial burden to outpatient clinics. Few studies have investigated patients' views on skin cancer follow-up and cutaneous melanoma. The objective was to investigate patients' perceived benefits and the impact of follow-up. MATERIAL AND METHODS...

  9. Hip-Hop to Health Jr. Randomized Effectiveness Trial: 1-Year Follow-up Results.

    Science.gov (United States)

    Kong, Angela; Buscemi, Joanna; Stolley, Melinda R; Schiffer, Linda A; Kim, Yoonsang; Braunschweig, Carol L; Gomez-Perez, Sandra L; Blumstein, Lara B; Van Horn, Linda; Dyer, Alan R; Fitzgibbon, Marian L

    2016-02-01

    The preschool years provide a unique window of opportunity to intervene on obesity-related lifestyle risk factors during the formative years of a child's life. The purpose of this study was to assess the impact of a preschool-based obesity prevention effectiveness trial at 1-year follow-up. RCT. Primarily African American children (aged 3-5 years, N=618) attending Head Start preschool programs administered by Chicago Public Schools. Eighteen preschools were randomly assigned in 2007-2008 to receive either (1) a 14-week teacher-delivered intervention focused on healthy lifestyle behaviors or (2) a 14-week teacher-delivered general health curriculum (control group). The primary outcome, BMI, was measured at baseline, postintervention, and 1-year follow-up. Diet and screen time behaviors were also assessed at these time points. Multilevel mixed effects models were used to test for between-group differences. Data were analyzed in 2014. Significant between-group differences were observed in diet, but not in BMI z-score or screen time at 1-year follow-up. Diet differences favored the intervention arm over controls in overall diet quality (p=0.02) and in subcomponents of diet quality, as measured by the Healthy Eating Index-2005, and in fruit intake (servings/day, excludes juice) (p=0.02). Diet quality worsened more among controls than the intervention group at 1-year follow-up. The adaptation of Hip-Hop to Health Jr. produced modest benefits in diet quality but did not significantly impact weight gain trajectory. Not unlike other effectiveness trials, this real-world version delivered by Head Start teachers produced fewer benefits than the more rigorous efficacy trial. It is important to understand and build upon the lessons learned from these types of trials so that we can design, implement, and disseminate successful evidence-based programs more widely and effectively. This study is registered at www.clinicaltrials.gov NCT00241878. Copyright © 2016 American Journal of

  10. Long-term results of the Ross procedure in a population-based follow-up.

    Science.gov (United States)

    Kallio, Merja; Pihkala, Jaana; Sairanen, Heikki; Mattila, Ilkka

    2015-05-01

    The purpose of this study was to evaluate the long-term outcomes of the Ross procedure in a nationwide follow-up. This retrospective study involved all children treated with the Ross procedure in Finland between 1994 and 2009. The clinical records were reviewed for demographic and anatomical characteristics, Ross operation data, surgical history and status at the latest follow-up. The median follow-up time was 11.5 (range 2.4-19.2) years. Fifty-one patients underwent either the Ross (n = 37) or the Ross-Konno (n = 14) procedure at a median age of 4.8 (range 0.02-16.3) years, including 13 infants (Ross procedure was aortic valve stenosis, regurgitation or both, which was observed in 29, 24 and 47% of patients, respectively. The early mortality (before hospital discharge) rate was 10% (31% in infants) and the late mortality rate 6% (15% in infants). Higher mortality was discovered in patients treated with the Ross-Konno procedure (P = 0.001). The most common cause for reintervention was pulmonary homograft stenosis. The rate of freedom from right ventricular outflow tract reintervention was 98% at 5 years, 83% at 10 years and 59% at 15 years. The rate of freedom from autograft reintervention was 98% at 5 and 10 years, and 81% at 15 years. At the latest follow-up visit, mild-to-moderate aortic root dilatation was reported in 52% of patients, and 4 patients had undergone autograft-related reinterventions. Trivial autograft valve regurgitation was commonly seen, but only 1 patient developed severe autograft regurgitation requiring mechanical valve replacement 15.9 years after the Ross operation. The most common reason for reintervention after the Ross procedure in children is homograft stenosis. Aortic root dilatation and autograft valve regurgitation are relatively common but rarely lead to reinterventions before adulthood. Intraoperative complications and complex cardiac anatomy are associated with high mortality in infants undergoing the Ross-Konno procedure. In our

  11. The importance of adequate follow-up in defining treatment success after external beam irradiation for prostate cancer

    International Nuclear Information System (INIS)

    Vicini, Frank A.; Kestin, Larry L.; Martinez, Alvaro A.

    1999-01-01

    median follow-up of 3 years for this cohort (range: 1 to 5 years). This process was repeated five times for five random samples of seven cohorts each. Biochemical failure was calculated according to the Consensus Panel definition. Results: In the first analysis, significantly different rates of biochemical control (varying by 6-21%) were calculated for the same actuarial year chosen for analysis depending only upon the length of follow-up used. For example, the 3-year actuarial rate of biochemical control (BC) varied from 71% when calculated with 3 years of follow-up versus 50.4% with 7 years (p < 0.01). These differences in actuarial rates of BC were observed in all subsets of patients analyzed (e.g., PSA < 10, Gleason ≤ 6, n = 132, p < 0.001; PSA < 10, Gleason ≥ 7, n = 33, p = 0.03; PSA ≥ 10, Gleason ≤ 6, n = 109, p < 0.001; and PSA ≥ 10, Gleason ≥ 7, n = 72, p = 0.002). The absolute magnitude of the difference in actuarial rates of BC was greatest during years 2 (range 18-30%), 3 (range 16-25%), and 4 (range 15-24%) after treatment. In the second analysis using median PSA follow-ups (as defined above), statistically significant differences in actuarial rates of BC were again observed. For example, the 3-year actuarial rate of BC varied from 74.8% with a median follow-up of 2 years versus 49.2% with a median follow-up of 6 years. These dramatic differences in BC were still observed beyond 5 years. Conclusion: When the ASTRO Consensus Panel definition of BF is used to calculate treatment success with external beam RT for prostate cancer, adequate follow-up is critical. Depending upon the length of time after treatment, significantly different rates of BC (varying by 15% to 30%) can be calculated for the same time interval chosen for analysis. These results suggest that data should only be reported if the length of follow-up extends at least beyond the time point at which actuarial results are examined for the majority of patients

  12. One-year follow-up study of psychotic patients treated with blonanserin: a case series.

    Science.gov (United States)

    Takahashi, Sakae; Suzuki, Masahiro; Uchiyama, Makoto

    2013-09-01

    Blonanserin is a relatively new atypical antipsychotic drug, and has been used in Korea and Japan for 1 and 3 years, respectively. Therefore, the clinical characteristics of blonanserin remain unclear. In this study, to clarify the features of blonanserin, we performed prospective and long-term comparative investigations of patients treated with blonanserin. We followed 10 psychiatric patients who were switched to blonanserin from other antipsychotics for 1 year (schizophrenia: 8; mental retardation: 2). In the light of quality of life, we focused on adverse effects of patients during the follow-up. In the long-term follow-up, (i) hyperprolactinemia is more frequently in risperidone than in blonanserin; however, it is more often in blonanserin than in olanzapine; and (ii) weight gain is more common in olanzapine than in blonanserin. We switched to blonanserin from other antipsychotic drugs within the same case, and then followed the case for 1 year. We consider that long-term observations within the same case lead to obvious comparisons among drugs. On the basis of our findings, we conclude that blonanserin may be useful for the maintenance treatment of schizophrenia without inducing hyperprolactinemia and weight gain. Copyright © 2012 Wiley Publishing Asia Pty Ltd.

  13. Induction of Maturogenesis by Partial Pulpotomy: 1 Year Follow-Up

    Directory of Open Access Journals (Sweden)

    A. Bacaksiz

    2013-01-01

    Full Text Available In cariously exposed immature permanent teeth, the treatment choice is controversial in pediatric dentistry. Radical root canal treatment usually appears to be the solution for these teeth. Even partial pulpotomy is a vital treatment for traumatically exposed immature permanent teeth; extending the borders of indication towards cariously exposed immature permanent teeth with reversible pulpitis may abolish the necessity of pulpectomy. This article describes the partial pulpotomy of a cariously affected immature permanent teeth and the follow-up for 1 year. A healthy 11-year-old male patient was referred to Gazi University Faculty of Dentistry Department of Pediatric Dentistry. The patient had reversible pulpitis symptoms on teeth numbered 45. At radiographic examination, immature apex and deep caries lesion were observed and partial pulpotomy was performed by using calcium hydroxide to maintain vitality of the pulp and allow continued development of root dentin expecting the root will attain full maturity. Clinical and radiographic follow-up demonstrated a vital pulp besides not only closure of the apex (apexogenesis, but also physiologic root development (maturogenesis after 1 year. Partial pulpotomy is an optional treatment for cariously exposed immature permanent teeth for preserving vitality and physiological root development.

  14. Semi-automated volumetric analysis of lymph node metastases during follow-up--initial results.

    Science.gov (United States)

    Fabel, Michael; Bolte, H; von Tengg-Kobligk, H; Bornemann, L; Dicken, V; Delorme, S; Kauczor, H-U; Heller, M; Biederer, J

    2011-04-01

    Quantification of tumour burden in oncology requires accurate and reproducible evaluation. The current standard is RECIST measurement with its inherent disadvantages. Volumetric analysis is an alternative for therapy monitoring. The aim of this study was to evaluate the feasibility of volumetric analysis of lymph node metastases using a software prototype in a follow-up setting. MSCT was performed in 50 patients covering the chest, abdomen and pelvis. A total of 174 suspicious lymph nodes were evaluated by two radiologists regarding short axis diameters and volumetric analysis using semi-automated software. Quality of segmentation, time, maximum diameter and volume were documented. Variability of the derived change rates was computed as the standard deviation of the difference of the obtained respective change rates. The software performance provides robust volumetric analysis. Quality of segmentation was rated acceptable to excellent in 76-79% by each reader. Mean time spent per lesion was 38 s. The variability of change in effective diameters was 10.6%; for change rates of RECIST maximum diameter variability was 27.5%. Semi-automated volumetric analysis allows fast and convenient segmentation of most lymph node metastases. Compared with RECIST the inter-observer-variability in baseline and follow-up is reduced. This should principally allow subtle changes to be subclassified within the RECIST stable range as minor response [-15% to +10%].

  15. Heart resynchronization therapy: experience, clinical Follow-up and optimization of the device with echocardiography

    International Nuclear Information System (INIS)

    Munera, Ana G; Restrepo, Gustavo; Duque, Mauricio; Cubides, Carlos; Uribe, William; Medina, Eduardo; Marin, Jorge; Gil, Efrain; Aristizabal, Dagnovar

    2007-01-01

    In patients with advanced heart failure, functional class lll-IV, mortality reaches 50% at one year and 80% at two years. Some remain asymptomatic and have a poor functional state, regardless of the pharmacologic treatment. Heart resynchronization therapy is a therapeutic alternative that improves hemodynamic and symptoms in these patients. The objective is to analyze the experience in the management of heart failure with heart resynchronization therapy devices with or without cardio defibrillator. Methodological design: an intervention study without aleatory patients assignment, with evaluation before and after the intervention. Results: the cohort was constituted by 82 patients. 73% were men. Mean age was 65.4+/- 11.9 years. The etiology was non-ischemic in 50 patients and ischemic in 32. Mean initial ejection fraction was 19.4% +/- 11.7%. Initial functional class was class lll - IV in 85% of cases and all patients received optimal medical treatment. During the follow-up, it was observed improvement of functional class, diastolic function, diastolic diameter of left ventricle, ejection fraction, mitral insufficiency, left atrial area, systolic lung pressure, synchrony parameters and myocardial function index with statistical significant difference in relation to the initial value (p<0.05). Survival at 44 months was 72%. Conclusion: the experience with heart resynchronization therapy and clinical and echocardiographic follow-up of the studied patients is similar to that found in other studies described in the literature

  16. The follow-up of progressive hypertrophic cardiomyopathy using magnetic resonance rotating frame relaxation times.

    Science.gov (United States)

    Khan, Muhammad Arsalan; Laakso, Hanne; Laidinen, Svetlana; Kettunen, Sanna; Heikura, Tommi; Ylä-Herttuala, Seppo; Liimatainen, Timo

    2018-02-01

    Magnetic resonance rotating frame relaxation times are an alternative non-contrast agent choice for the diagnosis of chronic myocardial infarct. Fibrosis typically occurs in progressive hypertrophic cardiomyopathy. Fibrosis has been imaged in myocardial infarcted tissue using rotating frame relaxation times, which provides the possibility to follow up progressive cardiomyopathy without contrast agents. Mild and severe left ventricular hypertrophy were induced in mice by transverse aortic constriction, and the longitudinal rotating frame relaxation times (T 1ρ ) and relaxation along the fictitious field (T RAFF2 , T RAFF3 ) were measured at 5, 10, 24, 62 and 89 days after transverse aortic constriction in vivo. Myocardial fibrosis was verified using Masson's trichrome staining. Increases in the relative relaxation time differences of T 1ρ , together with T RAFF2 and T RAFF3 , between fibrotic and remote tissues over time were observed. Furthermore, T RAFF2 and T RAFF3 showed higher relaxation times overall in fibrotic tissue than T 1ρ . Relaxation time differences were highly correlated with an excess of histologically verified fibrosis. We found that T RAFF2 and T RAFF3 are more sensitive than T 1ρ to hypertrophic cardiomyopathy-related tissue changes and can serve as non-invasive diagnostic magnetic resonance imaging markers to follow up the mouse model of progressive hypertrophic cardiomyopathy. Copyright © 2017 John Wiley & Sons, Ltd.

  17. Lupus nephritis. Remissions and relapses. Long-term follow up of 84 patients

    Directory of Open Access Journals (Sweden)

    Gerardo Oscar Mogni

    2014-06-01

    Full Text Available Introduction: Nephritis is the most common of all serious manifestations of SLE. The proliferative forms require immunosuppressive treatment, but responses are not consistent and exacerbations are frequent during or after the treatment has been completed. Methods: We retrospectively analyzed the evolution of a cohort of 84 patients with proliferative lupus nephritis with immunosuppressive treatment, in a long-term (up to 203 months follow up. Were taken as basal: sex, age, latency between onset and diagnosis of SLE nephritis, serum complement, plasmatic creatinine and proteinuria. We evaluated: initial response to therapy, occurrence of relapse or recurrence and score at the end of the observation period. Results: Remission of initial nephritis was seen in 73% of the cases, although at the end of monitoring only 54% of patients were in remission. 45 patients had one episode of nephritis, 32 patients had two, and 7 patients had three. Most of the remissions took place during the maintenance period. Complete remission had better evolution than partial remission. High serum creatinine levels and proteinuria at baseline were indicators of bad prognosis. Oral Azathioprine was more effective than quarterly IV Cylophosphamide as maintenance therapy, despite of a high incidence of relapses. Mycophenolate was not more effective than Cyclophosphamide/azathioprine for the treatment of relapses or recurrences. Conclusions: Our results are similar to the literature. Extended follow up enables the evaluation of the long term result of the initial symptoms, any possible future outbreaks, the effectiveness of the treatment and its evolution after its interruption.

  18. Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up.

    Science.gov (United States)

    van der Valk, Mirthe E; Mangen, Marie-Josée J; Severs, Mirjam; van der Have, Mike; Dijkstra, Gerard; van Bodegraven, Ad A; Fidder, Herma H; de Jong, Dirk J; van der Woude, C Janneke; Romberg-Camps, Mariëlle J L; Clemens, Cees H M; Jansen, Jeroen M; van de Meeberg, Paul C; Mahmmod, Nofel; van der Meulen-de Jong, Andrea E; Ponsioen, Cyriel Y; Bolwerk, Clemens; Vermeijden, J Reinoud; Siersema, Peter D; Leenders, Max; Oldenburg, Bas

    2016-01-01

    With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver. We aimed to explore the evolution of IBD-related costs over two years of follow-up. In total 1,307 Crohn's disease (CD) patients and 915 ulcerative colitis (UC) patients were prospectively followed for two years by three-monthly web-based questionnaires. Changes of healthcare costs, productivity costs and out-of-pocket costs over time were assessed using mixed model analysis. Multivariable logistic regression analysis was used to identify costs drivers. In total 737 CD patients and 566 UC were included. Total costs were stable over two years of follow-up, with annual total costs of €7,835 in CD and €3,600 in UC. However, within healthcare costs, the proportion of anti-TNF therapy-related costs increased from 64% to 72% in CD (pyears in UC (adj. OR 4.72 (95% CI 1.61-13.86)). BD-related costs remained stable over two years. However, the proportion of anti-TNF-related healthcare costs increased, while hospitalization costs decreased. Factors associated with increased costs were penetrating disease course in CD and age <40 in UC.

  19. Strategies for the Follow-up of Gravitational Wave Transients with the Cherenkov Telescope Array

    Science.gov (United States)

    Bartos, I.; Girolamo, T. Di; Gair, J. R.; Hendry, M.; Heng, I. S.; Humensky, T. B.; Márka, S.; Márka, Z.; Messenger, C.; Mukherjee, R.; Nieto, D.; O'Brien, P.; Santander, M.

    2018-03-01

    The observation of the electromagnetic counterpart of gravitational-wave (GW) transient GW170817 demonstrated the potential in extracting astrophysical information from multimessenger discoveries. The forthcoming deployment of the first telescopes of the Cherenkov Telescope Array (CTA) observatory will coincide with Advanced LIGO/Virgo's next observing run, O3, enabling the monitoring of gamma-ray emission at E > 20 GeV, and thus particle acceleration, from GW sources. CTA will not be greatly limited by the precision of GW localization as it will be be capable of rapidly covering the GW error region with sufficient sensitivity. We examine the current status of GW searches and their follow-up effort, as well as the status of CTA, in order to identify some of the general strategies that will enhance CTA's contribution to multimessenger discoveries.

  20. The Fermi GBM and LAT follow-up of GW150914

    Directory of Open Access Journals (Sweden)

    Bissaldi E.

    2017-01-01

    Here we present observations by the Fermi Gamma-Ray BurstMonitor (GBM [1] and by the Large Area Telescope (LAT [2] of the LIGO Gravitational Wave event GW150914, which has been associated to the merger of two stellar-mass BHs. We report the presence of a weak transient event in GBM data, close in time to the LIGO one. We discuss the characteristics of this GBM transient, which are consistent with a weak short GRB arriving at a large angle to the direction in which Fermi was pointing. Furthermore, we report LAT upper limits (ULs for GW150914, and we present the strategy for follow-up observations of GW events with the LAT.

  1. Swift Heavy Ions in Matter

    International Nuclear Information System (INIS)

    1989-01-01

    The 1989 Symposium on Swift Heavy Ions in Matter is reported. The aim of the symposium is to evidence another aspect of heavy ions research at the interplay between atomic and solid state physics. The scope of the Symposium includes the fundamental aspects of heavy ion excitation, ionization, charge exchange, energy loss, energy dissipation and relaxation in solids, channeling and coherent effects in crystals and ion induced modifications of materials

  2. Nanopatterning by Swift Heavy Ions

    OpenAIRE

    Skupinski, Marek

    2006-01-01

    Today, the dominating way of patterning nanosystems is by irradiation-based lithography (e-beam, DUV, EUV, and ions). Compared to the other irradiations, ion tracks created by swift heavy ions in matter give the highest contrast, and its inelastic scattering facilitate minute widening and high aspect ratios (up to several thousands). Combining this with high resolution masks it may have potential as lithography technology for nanotechnology. Even if this ‘ion track lithography’ would not give...

  3. Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study.

    Science.gov (United States)

    Demmo, Christine; Lagerberg, Trine Vik; Aminoff, Sofie R; Hellvin, Tone; Kvitland, Levi R; Simonsen, Carmen; Haatveit, Beathe; Andreassen, Ole A; Melle, Ingrid; Ueland, Torill

    2017-03-01

    Neurocognitive impairment has been found to be a marked feature in bipolar disorder (BD), also in the early phase of the illness. The longitudinal course of neurocognitive functioning, however, remains sparsely investigated. The aims of the study were to investigate the course of neurocognitive function in BD I, and to what degree neurocognitive change or stability is observed also on the individual level. Forty-two patients and 153 comparable healthy controls were assessed at baseline and one-year follow-up. Compared to the healthy control (HC) group BD I patients perform significantly poorer at both baseline and follow-up across all neurocognitive domains and on most neurocognitive subtests. Neurocognitive impairment remained stable for most patients from baseline to follow-up, both on a group level and when investigating individual trajectories, indicative of a relatively stable course of neurocognitive functioning in the early phase of BD I. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  4. Cost implications of human and automated follow-up in ambulatory care.

    Science.gov (United States)

    Berner, Eta S; Burkhardt, Jeffrey H; Panjamapirom, Anantachai; Ray, Midge N

    2014-11-01

    To compare the costs of human and automated follow-up processes in ambulatory care. Analysis of costs of nurse-initiated and interactive voice response (IVR) system follow-up interventions. Using national cost data and data on follow-up processes and outcomes from a previous study, we examined the costs to the healthcare system and providers of developing a follow-up process using nurse-initiated telephone calls compared with calls made by an IVR. Whether using nurse-initiated telephone calls or IVR calls, costs over the first 2 years of follow-up for a practice assumed to have 4800 acute care patient visits per year are approximately the same. After 2 years, IVR follow-up is approximately $9000 per year less expensive than nurse follow-up. In addition, overall cost savings are greater with IVR. Follow-up of ambulatory care patients is a way to assess risks of future problems and associated costs and to improve quality of care. An automated follow-up process using IVR is more efficient than one based on nurse-initiated follow-up calls.

  5. Follow-up skeletal surveys for nonaccidental trauma: can a more limited survey be performed?

    International Nuclear Information System (INIS)

    Harlan, Susan R.; Nixon, G.W.; Prince, Jeffrey S.; Campbell, Kristine A.; Hansen, Karen

    2009-01-01

    Studies have demonstrated the value of the follow-up skeletal survey in identifying additional fractures, clarifying indeterminate findings, and improving dating of skeletal injuries in victims of physical abuse. To determine whether a more limited follow-up survey could yield the same radiologic data as a full follow-up survey. The study cohort comprised 101 children who had follow-up surveys that met our inclusion criteria. Consensus readings of both original and follow-up surveys were performed by two pediatric radiologists. These results were compared to determine additional findings from the follow-up surveys. Limited skeletal survey protocols were evaluated to determine whether they would detect the same fractures seen with a complete osseous survey. In the 101 children 244 fractures were identified on the initial osseous survey. Follow-up surveys demonstrated new information in 38 children (37.6%). A 15-view limited follow-up survey identified all additional information seen on the complete follow-up survey. Our data demonstrate that a 15-view limited follow-up skeletal survey could be performed without missing clinically significant new fractures and still allow proper identification of confirmed fractures or normal findings. A limited survey would decrease radiation dose in children. (orig.)

  6. Follow-up skeletal surveys for nonaccidental trauma: can a more limited survey be performed?

    Energy Technology Data Exchange (ETDEWEB)

    Harlan, Susan R. [University of Utah School of Medicine, Department of Radiology, Salt Lake City, UT (United States); Nixon, G.W.; Prince, Jeffrey S. [Primary Children' s Medical Center, Department of Medical Imaging, Salt Lake City, UT (United States); Campbell, Kristine A.; Hansen, Karen [University of Utah School of Medicine, Department of Pediatrics, Salt Lake City, UT (United States)

    2009-09-15

    Studies have demonstrated the value of the follow-up skeletal survey in identifying additional fractures, clarifying indeterminate findings, and improving dating of skeletal injuries in victims of physical abuse. To determine whether a more limited follow-up survey could yield the same radiologic data as a full follow-up survey. The study cohort comprised 101 children who had follow-up surveys that met our inclusion criteria. Consensus readings of both original and follow-up surveys were performed by two pediatric radiologists. These results were compared to determine additional findings from the follow-up surveys. Limited skeletal survey protocols were evaluated to determine whether they would detect the same fractures seen with a complete osseous survey. In the 101 children 244 fractures were identified on the initial osseous survey. Follow-up surveys demonstrated new information in 38 children (37.6%). A 15-view limited follow-up survey identified all additional information seen on the complete follow-up survey. Our data demonstrate that a 15-view limited follow-up skeletal survey could be performed without missing clinically significant new fractures and still allow proper identification of confirmed fractures or normal findings. A limited survey would decrease radiation dose in children. (orig.)

  7. INT WFC follow-up photometry of the M31 nova M31N 2017-10a

    Science.gov (United States)

    Hermosa-Munoz, L.; Garcia-Rivas, M.; Gonzalez-Cuesta, L.; Jimenez-Gallardo, A.; Mantero-Castaneda, E. A.; Arce-Tord, C.; Prendin, M. G.; Rodriguez-Sanchez, M.; Esteban-Gutierrez, A.; Garcia-Broock, E.; Hernandez-Sanchez, M.; Lopez-Navas, E.; Otero-Santos, J.; Perez-Fournon, I.

    2017-12-01

    We report follow-up photometry in the Sloan g, r, and i bands, 240s per band, of the nova M31N 2017-10a ( = PNV J00423905+4123006) from observations on the night of 29 October 2017 with the Wide Field Camera of the Isaac Newton Telescope*.

  8. Right and left cardiac function in HIV-infected patients investigated using radionuclide ventriculography and brain natriuretic peptide: a 5-year follow-up study

    DEFF Research Database (Denmark)

    Kristoffersen, U.S.; Lebech, A.M.; Gerstoft, J.

    2008-01-01

    LVEF at both examinations. A minimal increase in mean LVEF of 0.02 was observed at follow-up (P=0.01). At the initial visit, four patients [6%; 95% confidence interval (CI) 2-15%] had a reduced RVEF, and at follow-up two patients (3%; 95% CI 0-11%) had slightly reduced RVEF. No significant change...

  9. Breast cancer after multiple chest fluoroscopies: second follow-up of Massachusetts women with tuberculosis

    International Nuclear Information System (INIS)

    Hrubec, Z.; Boice, J.D. Jr.; Monson, R.R.; Rosenstein, M.

    1989-01-01

    A second follow-up was conducted of 1742 women with tuberculosis who were treated in one of two sanatoria in Massachusetts between 1930 and 1956. One hospital treated only children under the age of 17. Patient follow-up was extended from 1975 through 1980, and an additional 18 breast cancers were identified from hospital records, death certificates, and responses to a mailed questionnaire. Vital status was established for 97% of the subjects. Among 1044 women who were examined an average of 101 times with X-ray fluoroscopies during lung collapse therapy, 55 breast cancers were observed in contrast to 35.8 expected, based on incidence rates from the general population. No excess was found for 698 women treated by other means (19 observed versus 22.8 expected). Excess breast cancer risk did not appear until 15 years after initial exposure and was present at the end of 50 years of observation. Risk appeared to decrease with increasing age at exposure. Estimates of radiation dose to the breast for individuals (mean = 96 rad) were based on the most current information for the numbers of fluoroscopies, reconstruction of exposure conditions, and absorbed dose calculations. The relation between dose and breast cancer risk was consistent with linearity up to 400 rads (4 Gy). For 10-year survivors, the absolute excess risk was 5.5/1 million woman-year-rad, the excess relative risk per rad was 0.73%, and the relative risk at 100 rad was 1.7. These data indicate that a woman's lifetime risk of breast cancer is influenced by events occurring in early reproductive life, that low-dose fractionated exposures are as effective as single exposures of the same total dose in inducing breast cancer, and that risk of radiogenic breast cancer persists for many years, and perhaps for life

  10. Nurse-led telephone follow-up after total knee arthroplasty

    DEFF Research Database (Denmark)

    Szöts, Kirsten; Konradsen, Hanne; Solgaard, Søren

    2015-01-01

    follow-up consultations and individual interviews with 10 patients formed the data material. Content analysis was used for the analysis. RESULTS: The content of the telephone follow-ups included dialogues relating to all key subjects for nursing status except 'culture/spirituality'. The structured......AIM AND OBJECTIVES: To generate information on how telephone follow-up consultations, structured by nursing status according to the VIPS-model, functioned after total knee arthroplasty. The objectives were to unfold the content of the telephone follow-ups according to the structure for nursing...... of health problems. A clinical trial was conducted to evaluate the effect of telephone follow-up, and information on how the telephone follow-ups functioned is relevant for implementation into clinical practice. DESIGN: A qualitative design was used. METHOD: One hundred and four case reports from telephone...

  11. Food of the Little Swift Apus affinis and African Black Swift Apus ...

    African Journals Online (AJOL)

    The food habits of the Little Swift Apus affinis and African Black Swift Apus barbatus were quantified at Kimberley, Northern Cape province and Makapansgat, Limpopo province, South Africa. As previously documented for other species, both of these swifts took a wide variety of aerial arthropods including spiders as well as ...

  12. Ischemic heart disease after mantlefield irradiation for Hodgkin's disease in long-term follow-up

    International Nuclear Information System (INIS)

    Reinders, J.G.; Heijmen, B.J.M.; Olofsen-van Acht, M.J.J.; Putten, W.L.J. van; Levendag, P.C.

    1999-01-01

    Background and purpose: In patients with Hodgkin's disease treated by radiotherapy with a moderate total dose and a low (mean) fraction dose to the heart, the risk of ischemic heart disease was investigated during long-term follow-up.Materials and methods: The medical records of 258 patients treated in the period 1965-1980 with radiotherapy alone as the primary treatment were reviewed. The median follow-up was 14.2 years (range 0.7-26.2). The mean total dose and fraction dose to the heart were 37.2 Gy (SD 2.9) and 1.64 Gy (SD 0.09), respectively. The impact on the development of ischemic heart disease of treatment-related parameters, such as the applied (fraction) dose, irradiation technique (one or two fields per day), and chemotherapy in case of a relapse, was investigated. The incidence of ischemic heart disease in this patient population was compared with the expected incidence based on gender, age and calendar period-specific data for the Dutch population.Results: Thirty-one patients (12%) experienced ischemic heart disease (actuarial risk at 20-25 years: 21.2% (95% C.I. 15-30). Twenty-five of them were hospitalized. When compared with the expected incidence, the relative risk (RR) of hospital admission for ischemic heart disease was 2.7 (95% C.I. 1.7-4.0). There were 12 deaths (4.7%) due to ischemic myocardial or sudden death (actuarial risk at 25 years: 10.2% (95% C.I. 5.3-19), compared to 2.3 cases that were expected to have died from these causes, yielding a standardized mortality ratio (SMR) of 5.3 (95% C.I. 2.7-9.3). Gender (male), pretreatment cardiac medical history and increasing age appeared to be the only significant factors for the development of ischemic heart disease.Conclusions: Despite the moderate total dose and the low (mean) fraction dose to the heart, the observed incidence of ischemic heart disease is high, especially after long follow-up periods. Treatment related cardiac disease in patients treated for Hodgkin's disease has only been

  13. Cognitive evolution in hypertensive patients: a six-year follow-up

    Directory of Open Access Journals (Sweden)

    Vicario A

    2011-05-01

    Full Text Available Augusto Vicario1,2,3, Mildren A del Sueldo2,3, Judith M Zilberman2,3, Gustavo H Cerezo2,31Department of Internal Medicine, Cardiovascular Division, Hospital Español de Buenos Aires, Argentina; 2Argentine Federation of Cardiology, (AFC, Buenos Aires, Argentina; 3Research Group, Human Health Commission, CERTUS Foundation, Buenos Aires, Argentina Background: Several studies have examined the links between hypertension, vascular damage, and cognitive impairment. The functions most commonly involved seem to be those associated with memory and executive function.Aims: 1 to report the cognitive evolution in a cohort of hypertensive patients, 2 to identify the affected domains, and 3 to correlate the results obtained with blood pressure measurements.Materials and Methods: Observational 6-year follow-up cohort study including both males and females aged ≥65 and ≤80 years, and hypertensive patients under treatment. Patients with a history of any of the following conditions were excluded: stroke, transient ischemic attack, diabetes mellitus, atrial fibrillation, cardiac surgery, dementia, or depression. Four neurocognitive evaluations were performed (at baseline and every 2 years. The tests used evaluated memory and executive function domain. Blood pressure was measured on every cognitive evaluation.Results: Sixty patients were followed for 76.4 ± 2.8 months. The average age at baseline was 72.5 ± 4.2 and 77.9 ± 4.6 at 6 years (65% were women. Two patients were lost to follow up (3.3% and 8 patients died (13.3%.The density incidence for dementia was 0.6% patients per year (pt/y (n = 3 and for depression was 1.6% pt/y (n = 12. No changes were observed in either memory impairment or the Mini Mental State Examination (MMSE results (p = ns during follow-up. A progressive impairment of the executive function was shown regardless of the blood pressure measurements.Conclusion: 1 the incidence of dementia doubled to general population, 2 the initial memory

  14. Results from the LCOGT Near-Earth Object Follow-up Network

    Science.gov (United States)

    Greenstreet, Sarah; Lister, Tim; Gomez, Edward; Christensen, Eric; Larson, Steve

    2015-11-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) has deployed a homogeneous telescope network of nine 1-meter and two 2-meter telescopes to five locations in the northern and southern hemispheres, with plans to extend to twelve 1-meter telescopes at 6 locations. The versitility and design of this network allows for rapid response to target of opportunity events as well as the long-term monitoring of slowly changing astronomical phenomena. The network's global coverage and the apertures of telescopes available make LCOGT ideal for follow-up and characterization of Solar System objects (e.g. asteroids, Kuiper Belt Objects, comets, Near-Earth Objects (NEOs)) and ultimately for the discovery of new objects.LCOGT has completed the first phase of the deployment with the installation and commissioning of the nine 1-meter telescopes at McDonald Observatory (Texas), Cerro Tololo (Chile), SAAO (South Africa) and Siding Spring Observatory (Australia). This is complimented by the two 2-meter telescopes at Haleakala (Hawaii) and Siding Spring Observatory. The telescope network has been fully operational since May 2014, and observations are being executed remotely and robotically. Future expansion to sites in the Canary Islands and Tibet are planned for 2016.The LCOGT near-Earth object group is using the network to confirm newly detected NEO candidates produced by the major sky surveys such as Catalina Sky Survey (CSS), PanSTARRS (PS1) and NEOWISE, with several hundred targets being followed per year. Follow-up astrometry and photometry of radar-targeted objects and those on the Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) or Asteroid Retrieval Mission (ARM) lists are improving orbits, producing light curves and rotation periods, and better characterizing these NEOs. Recent results include the first period determinations for several of the Goldstone-targeted NEOs. In addition, we are in the process of building a NEO portal that will allow

  15. A Decade of GRB Follow-Up by BOOTES in Spain (2003–2013

    Directory of Open Access Journals (Sweden)

    Martin Jelínek

    2016-01-01

    Full Text Available This article covers ten years of GRB follow-ups by the Spanish BOOTES stations: 71 follow-ups providing 23 detections. Follow-ups by BOOTES-1B from 2005 to 2008 were given in a previous article and are here reviewed and updated, and additional detection data points are included as the former article merely stated their existence. The all-sky cameras CASSANDRA have not yet detected any GRB optical afterglows, but limits are reported where available.

  16. Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up

    OpenAIRE

    Korfage, I J; Essink-Bot, M-L; Janssens, A C J W; Schr?der, F H; de Koning, H J

    2006-01-01

    To document anxiety and depression from pretreatment till 5-year follow-up in 299 men with localized prostate cancer. To assess, if baseline scores were predictive for anxiety and depression at 1-year follow-up. Respondents completed four assessments (pretreatment, at 6 and 12 months, and at 5-year follow-up) on anxiety, depression and mental health. Respondents were subdivided according to therapy (prostatectomy or radiotherapy) and high vs low-anxiety. Pretreatment 28% of all patients were ...

  17. Follow-up of Indigenous-specific health assessments - a socioecological analysis.

    Science.gov (United States)

    Bailie, Jodie; Schierhout, Gill H; Kelaher, Margaret A; Laycock, Alison F; Percival, Nikki A; O'Donoghue, Lynette R; McNeair, Tracy L; Chakraborty, Amal; Beacham, Barbara D; Bailie, Ross S

    2014-06-16

    To describe patterns of uptake of Indigenous-specific health assessments and associated follow-up items, and examine the barriers and enablers to delivery and billing of follow-up over the first 3 years of implementation of the Indigenous Chronic Disease Package (ICDP). We used a socioecological approach to analyse data derived from the Sentinel Sites Evaluation of the ICDP - with data from 24 sites across Australia. Administrative data (1 May 2009 to 30 May 2012) and program data (1 March 2010 to 30 May 2012) were provided by the Department of Health. Data on barriers and enablers to follow-up of health assessments were obtained from community focus groups, in-depth interviews and discussions with key informants (1 November 2010 to 30 December 2012). Monthly number of Medicare Benefits Schedule items claimed for Indigenous-specific health services and follow-up; qualitative data on enablers and barriers categorised according to patient, patient-health service relationship, health service or organisation, community and policy environment levels or influence. There was an increase in the uptake of health assessments, but relatively limited delivery of follow-up care and billing for Indigenous-specific follow-up items. Follow-up was constrained by factors that operated at various levels: patient, interpersonal, health service, community and policy. Constraints included practitioners' lack of awareness of item numbers, staffing, poor state of clinical information systems, billing against non-Indigenous-specific items or more general follow-up items, emphasis on health assessments with less attention to requirements for follow-up, limited capacity to arrange and facilitate follow-up, and communication and transport challenges for patients. Work is required across various levels of the system to address barriers to follow-up care. Enhancing follow-up care is vital to achieving health benefits from the large financial and human resource investment in health assessments.

  18. Mortality in parents after death of a child in Denmark: A nationwide follow-up study

    DEFF Research Database (Denmark)

    Li, Jiong; Precht, Dorthe Hansen; Mortensen, Preben Bo

    2003-01-01

    a child who had died (exposed cohort), and 293745 controls--ie, parents whose children were alive, and whose family structure matched that of the exposed cohort. Natural deaths were defined with ICD8 codes 0000-7969 and ICD10 codes A00-R99, and unnatural deaths with codes 8000-9999 and V01-Y98. We used......BACKGROUND: Little is known about the effect of parental bereavement on physical health. We investigated whether the death of a child increased mortality in parents. METHODS: We undertook a follow-up study based on national registers. From 1980 to 1996, we enrolled 21062 parents in Denmark who had...... Cox's proportional-hazards regression models to assess the mortality rate of parents up to 18 years after bereavement. FINDINGS: We observed an increased overall mortality rate in mothers whose child had died (hazards ratio 1.43, 95% CI 1.24-1.64; p

  19. Primary Progressive Orofacial Apraxia: A Ten-Year Long Follow-Up Case Report.

    Science.gov (United States)

    Trebbastoni, Alessandro; D'Antonio, Fabrizia; de Lena, Carlo; Onesti, Emanuela; John, Bev; Inghilleri, Maurizio

    2016-10-04

    Orofacial apraxia (OA) as the main symptom in neurodegenerative disorders has not been yet reported. We present the case of a woman with a 22-month long history of isolated OA, studied with cerebrospinal fluid biomarkers and repeated clinical, neuropsychological, and morpho-functional evaluations. Baseline morpho-functional neuroimages revealed a left frontal operculum hypoperfusion with a widespread fronto-temporal involvement at follow-up. Cerebrospinal fluid concentrations of tau and amyloid-β were normal. The ten-year long clinical observation disclosed progressive OA worsening and the late onset of frontal functions impairment and extrapyramidal signs. The early and late stages of a neurodegenerative syndrome with OA as the main clinical feature were characterized.

  20. L-Band Wide Follow-up Survey: Interesting Candidates and IDL Routines

    Science.gov (United States)

    Nichols, Nathan; Grzeskowiak, S.; Murray, K.; Troischt, P.; ALFALFA Team

    2014-01-01

    ALFALFA-U is a collaborative undertaking of faculty and students at 19 institutions, performing research using the ALFALFA blind HI survey and the L-Band Wide (LBW) follow-up survey. The primary goal of the LBW survey is to conduct targeted L-band Wide observations of the most interesting ALFALFA sources. This included the following four categories: 1. dark galaxy candidates, 2. OH Megamaser candidates, 3. extreme gas-dominated dwarf galaxy candidates, and 4. statistical samples of low signal to noise sources associated with optical counterparts. An IDL (Interactive Data Language) routine was developed to reduce the LBW data, provide integrated fluxes of the signals and calculate RMS noise. There were 312 definite detections and 328 possible detections of 1256 possible sources. This work has been supported by NSF grants AST-1211005 and AST-0725267.

  1. A follow-up study by CT and MRI in 3 cases of Japanese encephalitis

    International Nuclear Information System (INIS)

    Shoji, H.; Murakami, T.; Murai, I.; Kida, H.; Sato, Y.; Kojima, K.; Abe, T.; Okudera, T.

    1990-01-01

    A follow-up study by CT and MRI in 3 cases of Japanese encephalitis (JE) was performed. Neurologically dementia, forced laughing, tetraplegia and parkinsonism were observed as sequelae. In the CT and MR scans about 3 years after the onset of JE, low-density areas (LDAs) or abnormal signal intensities had remained in the thalamus and basal ganglia. The abnormalities were also found in the brain stem. When the main lesions shown by CT and MRI were compared with those of the acute stage, T2-weighted MRI clearly revealed multiple small areas with high signal intensities, although the ones at the acute stage had showed diffuse abnormal signals. These findings may be useful in helping to identity a long time after the onset. (orig.)

  2. Randomized controlled clinical trial on proximal caries infiltration: three-year follow-up.

    Science.gov (United States)

    Meyer-Lueckel, H; Bitter, K; Paris, S

    2012-01-01

    We report the 3-year efficacy of resin infiltration (Icon, pre-product; DMG, Hamburg) to arrest progression of proximal non-cavitated caries lesions as compared with placebo treatment. In 22 young adults, 29 lesion pairs with radiographic extensions into the inner half of enamel up to the outer third of dentin were included (split-mouth design). All subjects received risk-related instructions for diet, flossing and fluoridation. No unwanted effects could be observed. Radiographically 1/26 test lesions (4%) and 11/26 control lesions (42%) had progressed (p = 0.002, McNemar). After 3-year follow-up, infiltration of proximal caries lesions can be said to be efficacious to reduce lesion progression. Copyright © 2012 S. Karger AG, Basel.

  3. Recent results of the follow-up of radium-224-treated ankylosing spondylitis patients

    International Nuclear Information System (INIS)

    Wick, R.R.; Goessner, W.

    1989-01-01

    In this study 1473 ankylosing spondylitis patients were followed after treatment with 10-12 weekly injections of radium 224 of about 1MBq each injections( skeletal dose 0.56-0.67 Gy for a 70 kg man). 495 in the exposure group and 602 in the controls have died. By June 1988 (mean follow-up time 17 years), 3 cases of skeletal malignancies were observed in the exposure group versus one in the controls. Haematopoietic tissue disease among living and dead included bone marrow failure (10 in the exposed, seven in controls), and leukemias (7 versus 4). In the exposure group 3 of the leukemias were chronic myeloid and one acute lymphoblastic, and in the controls no chronic myeloid cases were found but 3 cases of lymphoblastic leukemia. Incidence of myeloproliferative disease is discussed compared with patients treated with other doses and dose rates. (author)

  4. Long term follow up study of survival associated with cleft lip and palate at birth

    DEFF Research Database (Denmark)

    Christensen, Kaare; Juel, K.; Herskind, Anne Maria

    2004-01-01

    OBJECTIVE: To assess the overall and cause specific mortality of people from birth to 55 years with cleft lip and palate. DESIGN: Long term follow up study. SETTING: Danish register of deaths. PARTICIPANTS: People born with cleft lip and palate between 1943 and 1987, followed to 1998. MAIN OUTCOME...... MEASURES: Observed and expected numbers of deaths, summarised as overall and cause specific standardised mortality ratios. RESULTS: 5331 people with cleft lip and palate were followed for 170 421 person years. The expected number of deaths was 259, but 402 occurred, corresponding to a standardised...... of death. CONCLUSIONS: People with cleft lip and palate have increased mortality up to age 55. Children born with cleft lip and palate and possibly other congenital malformations may benefit from specific preventive health measures into and throughout adulthood....

  5. Retrospective analysis of follow-up results in patients with skin lymphomas of low degree malignancy

    Directory of Open Access Journals (Sweden)

    Tarasov V.V.

    2011-03-01

    Full Text Available Administration of specific chemotherapy (cytostatics has great significance in the treatment of skin lymphomas of low degree malignancy. The research goal is to study follow-up results of cytostatic therapy of skin lymphomas. Retrospective observation of survival of patients with T-cell epidermothropic skin lymphomas using special therapy and without its use has been studied. Comparative analysis of survival rate in two groups of patients has been done. 40 patients received cytostatics and 32 patents were not treated by chemotherapy. The first group of patients showed the reduction of survival level and increase of mortality level from skin lymphomas of low degree malignancy. The research findings proved the influence of cytostatic therapy on the survival of patients with skin lymphomas of low degree malignancy

  6. Patients highly value routine follow-up of skin cancer and cutaneous melanoma.

    Science.gov (United States)

    Themstrup, Lotte; Jemec, Gregor E; Lock-Andersen, Jørgen

    2013-10-01

    Skin cancer follow-up is a substantial burden to outpatient clinics. Few studies have investigated patients' views on skin cancer follow-up and cutaneous melanoma. The objective was to investigate patients' perceived benefits and the impact of follow-up. This study included an open sample of patients attending routine follow-up at the outpatient Departments of Plastic Surgery and Dermatology, Roskilde Hospital. A total of 218 follow-up patients diagnosed with cutaneous malignant melanoma (MM), non-melanoma skin cancer (NMSC) or actinic keratosis (AK) completed a structured interview. A total of 97% patients found follow-up useful. Continuity and consistency were important. One third of patients felt some degree of pre follow-up anxiety. The number of anxious MM patients was significantly greater than that of NMSC patients. No significant difference was found between the number of anxious MM and AK patients. Female gender, cohabitation and age younger than 50 years were associated with increased levels of anxiety. No relation was found between the number of anxious patients or the level of anxiety and the duration of the follow-up period. The majority of patients who attended found that the follow-up had been useful. Certain demographic characteristics were associated with higher levels of anxiety and may be addressed by supportive efforts targeting these groups.

  7. Optical Follow-Up of Gamma-Ray Bursts Observed by WATCH

    DEFF Research Database (Denmark)

    Castro-Tirado, A.; Brandt, Søren; Lund, Niels

    1994-01-01

    44 Gamma‐Ray Bursts have been localized by the WATCH experiments on GRANAT and EURECA. For some of them, Schmidt plates were taken within days after the burst. In other cases, time‐correlated plates were found in some of the main astronomical archives. No obvious optical counterpart has been found...

  8. Body mass and fat mass in refractory asthma: an observational 1 year follow-up study.

    Science.gov (United States)

    Bafadhel, Mona; Singapuri, Amisha; Terry, Sarah; Hargadon, Beverley; Monteiro, William; Green, Ruth H; Bradding, Peter H; Wardlaw, Andrew J; Pavord, Ian D; Brightling, Christopher E

    2010-01-01

    Background. Asthma and obesity are common; however the impact of obesity upon asthma remains uncertain. Objectives. To assess relationships between obesity and fat mass with airway inflammation, lung function, and disease control in patients with refractory asthma. Methods. 151 refractory asthma patients were characterised for measures of airway inflammation, lung function, Juniper asthma control questionnaire (JACQ), body mass index (BMI), and fat mass index (FMI) derived from dual energy X-ray absorptiometry. Patients were reassessed over 12 months. Results. 74% of patients had an elevated BMI. BMI and FMI correlated (r = 0.9, P < .001). FMI and JACQ correlated in men (r = 0.3, P = .01). After 12 months 23% lost weight. Weight change over 12 months correlated with FEV(1) change (r = -0.3, P = .03), but not with change in JACQ or exacerbations. Conclusion. Increased fat mass is common in refractory asthma and is associated with asthma symptom control in men. Loss of weight is associated with improvement in lung function in refractory asthma.

  9. Body Mass and Fat Mass in Refractory Asthma: An Observational 1 Year Follow-Up Study

    Directory of Open Access Journals (Sweden)

    Mona Bafadhel

    2010-01-01

    Full Text Available Background. Asthma and obesity are common; however the impact of obesity upon asthma remains uncertain. Objectives. To assess relationships between obesity and fat mass with airway inflammation, lung function, and disease control in patients with refractory asthma. Methods. 151 refractory asthma patients were characterised for measures of airway inflammation, lung function, Juniper asthma control questionnaire (JACQ, body mass index (BMI, and fat mass index (FMI derived from dual energy X-ray absorptiometry. Patients were reassessed over 12 months. Results. 74% of patients had an elevated BMI. BMI and FMI correlated (r=0.9, P<.001. FMI and JACQ correlated in men (r=0.3, P=.01. After 12 months 23% lost weight. Weight change over 12 months correlated with FEV1 change (r=−0.3, P=.03, but not with change in JACQ or exacerbations. Conclusion. Increased fat mass is common in refractory asthma and is associated with asthma symptom control in men. Loss of weight is associated with improvement in lung function in refractory asthma.

  10. Relevant traumatic injury of the knee joint-MRI follow-up after 7-10 years

    International Nuclear Information System (INIS)

    Crema, Michel D.; Marra, Monica D.; Guermazi, A.; Bohndorf, Klaus; Roemer, Frank W.

    2009-01-01

    Objective: To evaluate prospectively the history of relevant traumatic knee injuries at least 7 years after trauma by MRI focusing on the development of degenerative changes. Materials and methods: Seventeen patients without baseline degenerative changes had a follow-up knee MRI several years after relevant knee injury (interval baseline-follow-up was 9.1 years, S.D. ±1.3 years). Relevant knee injury was defined as complete cruciate or collateral ligament rupture, traumatic meniscal tear or osteochondral injury. Baseline MRI examinations were evaluated for traumatic ligamentous, chondral, meniscal and osseous lesions. Follow-up MRIs were evaluated for ligamentous and meniscal status, articular surface and incidence of degenerative changes such as cartilage loss, osteophytes and bone marrow lesions. Results: Among the 11 patients who had a complete rupture of the ACL at baseline, 3 (27.3%) presented with cartilage loss. Among the eight patients who had suffered a post-traumatic meniscal tear at baseline, four (50%) presented with cartilage loss at follow-up. Among the five patients who had an osteochondral fracture at baseline, two (40%) presented with cartilage loss at follow-up imaging. Cartilage loss in all cases was observed adjacent to the subregions where meniscal damage and/or osteochondral incongruence was/were present at follow-up imaging. Conclusion: We hypothesize that the post-traumatic or postsurgical meniscal damage and the persistence of an irregular articular surface may have played a role in the subsequent loss of cartilage in our patient population.

  11. Long-Term Electroclinical and Employment Follow up in Temporal Lobe Epilepsy Surgery. A Cuban Comprehensive Epilepsy Surgery Program

    Directory of Open Access Journals (Sweden)

    Lilia Maria Morales Chacón

    2018-02-01

    Full Text Available The purpose of this paper is to present a long- term electroclinical and employment follow up in temporal lobe epilepsy (TLE patients in a comprehensive epilepsy surgery program. Forty adult patients with pharmacoresistant TLE underwent detailed presurgical evaluation. Electroencephalogram (EEG and clinical follow up assessment for each patient were carried out. The occurrence of interictal epileptiform activity (IEA and absolute spike frequency (ASF were tabulated before and after 1, 6, 12, 24 and 72 months surgical treatment. Employment status pre- to post-surgery at the last evaluated period was also examined. Engel scores follow-up was described as follows: at 12 months 70% (28 class I, 10% (4 class II and 19% (8 class III-IV; at 24 months after surgery 55.2% (21 of the patients were class I, 28.9% (11 class II and 15.1% (6 class III-IV. After one- year follow up 23 (57.7% patients were seizure and aura-free (Engel class IA. These figures changed to 47.3%, and 48.6% respectively two and five years following surgery whereas 50% maintained this condition in the last follow up period. A decline in the ASF was observed from the first year until the sixth year after surgery in relation to the preoperative EEG. The ASF one year after surgery allowed to distinguish “satisfactory” from “unsatisfactory” seizure relief outcome at the last follow up. An adequate social functioning in terms of education and employment in more than 50% of the patients was also found. Results revealed the feasibility of conducting a successful epilepsy surgery program with favorable long term electroclinical and psychosocial functioning outcomes in a developing country as well.

  12. Primary psychosis with comorbid drug abuse and drug-induced psychosis: Diagnostic and clinical evolution at follow up.

    Science.gov (United States)

    Mauri, M C; Di Pace, C; Reggiori, A; Paletta, S; Colasanti, A

    2017-10-01

    The study reports a follow-up assessment of 48 patients with concomitant drug abuse at the first admission for psychosis. We focused on the diagnostic distinction between primary psychosis with concomitant drug abuse and drug induced psychosis, to observe whether the diagnoses are stable over time and whether the clinical course significantly differs. The study examined 25 primary psychotic disorder with comorbid drug abuse and 23 drug-induced psychotic disorder patients. Diagnostic and psychopathological assessments were made at baseline and at follow-up. Mean follow-up period was 4.96 years. Patients with comorbid Drug Abuse exhibited higher scores in the item Unusual Content of Thought at baseline than drug-induced psychotic disorder patients: 5.48 vs 4.39 while the two patients groups did not differ in any of the BPRS items evaluated at follow-up. The primary psychosis with comorbid drug abuse and the substance induced psychosis groups were similar regarding diagnostic stability, and a diagnosis of schizophrenia at follow-up occurred similarly. There was no evidence that Drug Induced psychotic patients' symptoms tend to improve more after cessation of drug abuse. An earlier age of onset was found in primary psychotic patients, particularly for patients diagnosed as affected by schizophrenia at follow up. These results might reflect the uncertainty of the distinction between Primary and Drug Induced Psychosis and the difficulties in applying the DSM IV-TR criteria for diagnosing comorbid drug use disorders and psychotic disorders. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. The Micra Leadless Transcatheter Pacemaker. Implantation and Mid-term Follow-up Results in a Single Center.

    Science.gov (United States)

    Martínez-Sande, José Luis; García-Seara, Javier; Rodríguez-Mañero, Moisés; Fernández-López, Xesús Alberte; González-Melchor, Laila; Redondo-Diéguez, Alfredo; González-Ferreiro, Rocío; González-Juanatey, José Ramón

    2017-04-01

    Currently, studies on the leadless pacemaker (Micra) have mostly been limited to clinical trials with less than 6 months' follow-up and they often fail to reflect real population outcomes. We sought to evaluate electrical parameters at implantation and chronologically during follow-up, as well as the safety of this new technique. This prospective, observational study included 30 consecutive patients, all ≥ 65 years, with an indication for single-chamber pacemaker implantation. Successful implantation was accomplished in all patients referred for leadless implantation. The mean age was 79.4±6.4 years (range, 66-89 years); 20 (66.6%) were men and 28 had permanent atrial fibrillation (93.3%); 1 had atrial tachycardia and 1 had sinus rhythm. Concomitant atrioventricular node ablation was performed immediately after implantation in 5 patients (16.6%), and implantation was performed after transcatheter aortic valve implantation in 2. The procedure was performed under an uninterrupted anticoagulation regimen (maximum INR 2.4) in 23 patients (76.6%). With the exception of 1 moderate pericardial effusion without tamponade, there were no severe complications. The mean follow-up was 5.3±3.3 months and 4 patients had more than 1 year of follow-up. Sensing and pacing parameters were stable both at implantation and during the short- to mid-term follow-up. Implantation of leadless pacemakers is feasible, safe and provides advantages over the conventional system. Further studies with longer follow-up periods will be needed before these devices become widely used in routine clinical practice. Copyright © 2016 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  14. Establishment of an inferior vena cava filter database and interventional radiology led follow-up - retrieval rates and patients lost to follow-up.

    Science.gov (United States)

    Klinken, Sven; Humphries, Charlotte; Ferguson, John

    2017-10-01

    To evaluate the rates of inferior vena cava (IVC) filter retrieval and the number of patient's lost to follow-up, before and after the establishment of an IVC filter database and interventional radiology (inserting physician) led follow-up. On the 1st of June 2012, an electronic interventional radiology database was established at our Institution. In addition, the interventional radiology team took responsibility for follow-up of IVC filters. Data were prospectively collected from the database for all patients who had an IVC filter inserted between the 1st June 2012 and the 31st May 2014. Data on patients who had an IVC filter inserted between the 1st of June 2009 to the 31st of May 2012 were retrospectively reviewed. Patient demographics, insertion indications, filter types, retrieval status, documented retrieval decisions, time in situ, trackable events and complications were obtained in the pre-database (n = 136) and post-database (n = 118) cohorts. Attempted IVC filter retrieval rates were improved from 52.9% to 72.9% (P = 0.001) following the establishment of the database. The number of patients with no documented decision (lost to follow-up) regarding their IVC filter reduced from 31 of 136 (23%) to 0 of 118 patients (P = database group (113 as compared to 137 days, P = 0.129). Following the establishment of an IVC filter database and interventional radiology led follow-up, we demonstrate a significant improvement in the attempted retrieval rates of IVC filters and the number of patient's lost to follow-up. © 2017 The Royal Australian and New Zealand College of Radiologists.

  15. The 105 month Swift-BAT data release

    Science.gov (United States)

    Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; Ricci, Claudio; Lien, Amy; Trakhtenbrot, Benny; NASA GSFC Swift BAT team, BAT AGN Spectroscopic Survey (BASS)

    2018-01-01

    We present a new catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) on board the Swift observatory. The 105 month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40×10-12 erg s-1 cm-2 over 90% of the sky and 7.24×10-12 erg s-1 cm-2 over 50% of the sky in the 14‑195 keV band. The Swift-BAT 105 month catalog provides 1632 (422 new detections) hard X-ray sources in the 14 ‑ 195 keV band above the 4.8σ significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert AGN in nearby galaxies (z BAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105 month Web site.

  16. [Follow up of total hip prothesis: storage phosphor versus screen-film radiography].

    Science.gov (United States)

    Polet, K; de La Selle, H; Leroux, J; Ludig, T; Girard, F; Coudane, H; Blum, A

    2003-03-01

    Digital radiography may lead to interpretation difficulties in patients with hip prosthesis, especially when initial evaluation was performed using screen film radiography. The purpose of this study was to evaluate inter-observer and inter-technique reproducibility comparing digital and screen-film radiography. Twenty-eight patients with unilateral (n=24) or bilateral (n=4) hip prosthesis (total=32 prostheses) underwent screen-film and digital (storage phosphor) radiography. The bone-cement and metal-cement interfaces were evaluated for the presence of a lucent line in 14 different sectors reclassified into 3 regions. This evaluation was performed by two independent readers. Inter-observer and inter-technique reproducibility were calculated using kappa values. The inter-observer reproducibility was negligible, poor or average with Kappa values ranging from 0.07 to 0.47. The degree of agreement between the two methods was poor, average or good for both observers with Kappa values ranging from 0.10 to 0.66. Although inter-technique agreement is not high, it is better than inter-observer agreement. Therefore, storage phosphor technique should not be rejected for total hip prosthesis follow-up, even though previous films were screen-film radiographs.

  17. IAEA Concludes Follow-up Review of Malaysia Rare Earth Plant IAEA Concludes Follow-up Review of Malaysia Rare Earth Plant

    International Nuclear Information System (INIS)

    2014-01-01

    In its preliminary observations, the follow-up mission found that good progress had been made in implementing the recommendations of the 2011 mission, and noted that the radiological risks of the Lynas plant are low because of the very low level of radioactivity of the materials handled. The team also noted that Malaysia is actively updating its regulations in accordance with the most recent IAEA safety standards. The IAEA team gave some advice for further progress in specific areas. For example: The waste management plan should be based on realistic scenarios including, if considered appropriate, the identification of a final disposal site. Environmental monitoring activities should be optimised to ensure resources are focused on the most important areas, including enhancing monitoring of liquid discharges. The basis of the financial fund to be paid by Lynas for long-term waste management and decommissioning should be communicated more clearly. The AELB and Lynas are encouraged to maintain a proactive approach to relations with the media, public and other stakeholders, on an ongoing basis, to address continuing widespread misconceptions about the plant and radiation issues in general. Rare earths are elements used in many high-technology applications, from mobile phones to wind turbines. Since the ore from which they are refined also usually contains naturally occurring radioactive materials such as thorium or uranium, the process results in very low-level radioactive waste that must be managed safely. The IAEA mission's final report will be submitted to the Malaysian government at the end of October, and will be made public

  18. A 10-year follow-up study of psychosocial factors affecting couples after infertility treatment.

    Science.gov (United States)

    Wischmann, T; Korge, K; Scherg, H; Strowitzki, T; Verres, R

    2012-11-01

    childless couples and in post-MAR parents. A decline of sexual satisfaction in childless couples (often reported in the literature) was not observed in this large sample. Quality of life in the long-term can safely be said to be high, both in the definitively childless couples and the post-MAR parents. These findings should be integrated into the information and counselling for would-be parents prior to infertility treatment. A major limitation of this study is that the majority of women and men from the initial study did not respond in our follow-up study.

  19. Effect of safe water on arsenicosis: A follow-up study

    Directory of Open Access Journals (Sweden)

    Kunal K Majumdar

    2014-01-01

    Full Text Available Background: Arsenic pollution in groundwater, used for drinking purposes, has been envisaged as a problem of global concern. Treatment options for the management symptoms of chronic arsenicosis are limited. Mitigation option available for dealing with the health problem of ground water arsenic contamination rests mainly on supply of arsenic safe water in arsenic-endemic region of Indo-Bangladesh subcontinent. Limited information is available regarding the long-term effect of chronic arsenic toxicity after stoppage of consumption of arsenic-containing water. Objective: The current study was, therefore, done to assess, objectively, the effect of drinking arsenic safe water (<50 μg/L on disease manifestation of arsenicosis. Results: Manifestations of various skin lesions and systemic diseases associated with chronic arsenic exposure were ascertained initially by carrying on baseline study on 208 participants in Nadia (Cohort-I, with skin lesion and Cohort-II, without skin lesion using a scoring system, as developed by us, and compared objectively at the end of each year for 3 year follow-up period. All the participants who had arsenic contaminated drinking water source in their houses were supplied with arsenic removal filters for getting arsenic-free water during the follow-up period. In participants belonging to Cohort-I, the skin score was found to improve significantly at the end of each year, and it was found to be reduced significantly from 2.17 ± 1.09 to 1.23 ± 1.17; P < 0.001 at the end of 3 year′s intervention study indicating beneficial effect of safe water on skin lesions. The systemic disease symptom score was also found to improve, but less significantly, at the end of 3 years in both the cohorts. Most important observation during the follow-up study was persistence of severe symptoms of chronic lung disease and severe skin lesion including Bowen′s disease in spite of taking arsenic-safe water. Further, death could not be

  20. Profile and pattern of follow-ups of psychiatry outpatients at Christian Medical College, Ludhiana

    Directory of Open Access Journals (Sweden)

    Mamta Singla

    2015-01-01

    Full Text Available Context: As psychiatric illness requires long-term treatment, some patients are lost to follow-up. Aims: The present study aimed to find the follow-up pattern of psychiatric patients attending psychiatry outpatient department (OPD and to determine the correlation of follow-up with socio-demographic profile and diagnosis, if any. Settings and Design: This study was a retrospective data analysis study carried out at the OPD of Psychiatry, Christian Medical College and Hospital, Ludhiana. Subjects and Methods: New cases attending the OPD from April 2010 to March 2011 were included in this study. The data were scrutinized 1 year after the initial assessment. Socio-demographic data, diagnosis and follow-up information were obtained from the files. The collected data were statistically analyzed. Statistical Analysis Used: Chi-square and P value. Results: 53.1% of the patients dropped out after first visit, 29.4% patients had 1-3 follow-up, 14.9% had 4-10 follow-ups and only 2.6% had more than 10 follow-ups. Correlation between follow-up and various socio-demographic variables such as age, gender, place of living or distance from hospital, occupation, religion and marital status was not statistically significant. It was, however, seen that cognitive disorders, conversion disorder, mental retardation, and patients in which diagnosis was deferred, had more dropout rate after first visit. Conclusions: In our study 53.1% of the patients did not attend follow-up at all and only 2.6% had more than 10 follow ups. Correlation between follow-up and various socio-demographic variables was not statistically significant. Patients in which diagnosis was deferred had more drop out rate than patients who had a diagnosis and the difference was statistically significant.

  1. Structured nursing follow-up: does it help in diabetes care?

    Science.gov (United States)

    Shani, Michal; Nakar, Sasson; Lustman, Alex; Lahad, Amnon; Vinker, Shlomo

    2014-01-01

    In 1995 Clalit Health Services introduced a structured follow-up schedule, by primary care nurses, of diabetic patients. This was supplementary care, given in addition to the family physician's follow-up care. This article aims to describe the performance of diabetes follow-up and diabetes control in patients with additional structured nursing follow-up care, compared to those patients followed only by their family physician. We randomly selected 2,024 type 2 diabetic subjects aged 40-76 years. For each calendar year, from 2005-2007, patients who were "under physician follow-up only" were compared to those who received additional structured nursing follow-up care. Complete diabetes follow-up parameters including: HbA1c, LDL cholesterol, microalbumin, blood pressure measurements and fundus examination. The average age of study participants was 60.7 years, 52% were females and 38% were from low socioeconomic status (SES). In 2005, 39.5% of the diabetic patients received structured nursing follow-up, and the comparable figures for 2006 and 2007 were 42.1% 49.6%, respectively. The intervention subjects tended to be older, from lower SES, suffered from more chronic diseases and visited their family physician more frequently than the control patients. Patients in the study group were more likely to perform a complete diabetes follow-up plan: 52.8% vs. 21.5% (2005; p nursing follow-up care were more likely to perform complete diabetes follow-up protocol. Our results reinforce the importance of teamwork in diabetic care. Further study is required to identify strategies for channeling the use of the limited resources to the patients who stand to benefit the most.

  2. Physicians' experience with follow-up care of childhood cancer survivors - challenges and needs.

    Science.gov (United States)

    Michel, Gisela; Gianinazzi, Micol Eva; Vetsch, Janine; Mader, Luzius; Lupatsch, Judith E; von der Weid, Nicolas X; Rueegg, Corina Silvia

    2017-07-19

    Regular follow-up care is essential for childhood cancer survivors, but we know little about physicians' experience with it. We aimed to describe: (1) involvement of Swiss physicians in follow-up care; (2) content of follow-up care provided; (3) problems encountered; and (4) additional resources needed. Within this cross-sectional survey we sent adapted questionnaires via professional associations to a sample of medical oncologists (MOs), paediatric oncologists (POs), general practitioners (GPs) and paediatricians (P) in Switzerland. Only oncologists involved in follow-up care were asked to report problems. GPs and Ps not involved in follow-up could indicate why. All physicians were asked about the content of follow-up care provided and additional resources needed. A total of 183 physicians responded (27 MO, 13 PO, 122 GP, 21 P). Involved in follow-up were 81% of MOs, 85% of POs, 39% of GPs and 81% of Ps. Follow-up content differed between oncologists (MO and PO) and generalists (GP and P), with generalists examining or informing less in regard to the former cancer. POs reported more problems than MOs: many POs reported problems with transition of survivors to adult care (91%), and because of financial resources (73%) and time restraints (73%). MOs reported most problems during transition (23%). Not being aware of a survivor was the most common reason for GPs and Ps not participating in follow-up (74%). All groups reported a need for standardised protocols (85-91%) and specialised training (55-73%). GPs (94%) and Ps (100%) additionally desired more support from oncologists. To improve quality and efficiency of follow-up care a national follow-up care model including standardised protocols and guidelines needs to be developed.

  3. Loss to follow-up in a cohort of HIV-negative men who have sex with men: Project Horizonte.

    Science.gov (United States)

    Silva, Ana Paula; Greco, Marília; Fausto, Maria Arlene; Carneiro, Mariângela

    2017-06-26

    The objective of this study is to estimate the attrition rates and evaluate factors associated with loss to follow-up between 1994 and 2011 in an open cohort of HIV-negative men who have sex with men. The Project Horizonte is an open cohort study that aimed to assess the incidence of HIV infection, evaluate the impact of educational interventions, and identify potential volunteers for HIV vaccine trials. The rates of losses to follow-up were estimated for three periods (1994-1999, 2000-2005, and 2006-2011). The variables analyzed were collected in a psychosocial questionnaire. Volunteers who dropped out were compared with the ones who remained in the study using a Cox regression model. A total of 1,197 volunteers were recruited. The median follow-up time in the study (n = 626) was 4.2 years. The median follow-up time for the volunteers who dropped out of the study (n = 571) was 1.46 years. The overall rate of loss to follow-up was 11.6/100 person-years. Attrition rates by period were: 12.60 (1994-1999), 11.80 (2000-2005), and 9.00 (2006-2011) per 100 person-years. Factors associated with losses to follow-up were: age group of 21-30 years old, monthly per capita income of more than six or less than one Brazilian minimum wage, having more than two dependents, report of bisexual practice, and inconsistent use of condoms for receptive anal sex. A slight decrease of the loss to follow-up was observed over time. Higher attrition rates happened in the first three years of follow-up. It is possible that the link of the volunteers were not yet well established. Those who reported inconsistent condom use in receptive anal sex were more likely to leave the study, suggesting an underestimation of the incidence of HIV infection in a cohort population. For greater effectiveness, retention strategies must be reassessed considering the connection between the characteristics of homosexual and bisexual behavior and the motivations to engage in health research.

  4. Loss to follow-up in a cohort of HIV-negative men who have sex with men: Project Horizonte

    Directory of Open Access Journals (Sweden)

    Ana Paula Silva

    Full Text Available ABSTRACT OBJECTIVE The objective of this study is to estimate the attrition rates and evaluate factors associated with loss to follow-up between 1994 and 2011 in an open cohort of HIV-negative men who have sex with men. METHODS The Project Horizonte is an open cohort study that aimed to assess the incidence of HIV infection, evaluate the impact of educational interventions, and identify potential volunteers for HIV vaccine trials. The rates of losses to follow-up were estimated for three periods (1994–1999, 2000–2005, and 2006–2011. The variables analyzed were collected in a psychosocial questionnaire. Volunteers who dropped out were compared with the ones who remained in the study using a Cox regression model. RESULTS A total of 1,197 volunteers were recruited. The median follow-up time in the study (n = 626 was 4.2 years. The median follow-up time for the volunteers who dropped out of the study (n = 571 was 1.46 years. The overall rate of loss to follow-up was 11.6/100 person-years. Attrition rates by period were: 12.60 (1994–1999, 11.80 (2000–2005, and 9.00 (2006–2011 per 100 person-years. Factors associated with losses to follow-up were: age group of 21–30 years old, monthly per capita income of more than six or less than one Brazilian minimum wage, having more than two dependents, report of bisexual practice, and inconsistent use of condoms for receptive anal sex. CONCLUSIONS A slight decrease of the loss to follow-up was observed over time. Higher attrition rates happened in the first three years of follow-up. It is possible that the link of the volunteers were not yet well established. Those who reported inconsistent condom use in receptive anal sex were more likely to leave the study, suggesting an underestimation of the incidence of HIV infection in a cohort population. For greater effectiveness, retention strategies must be reassessed considering the connection between the characteristics of homosexual and bisexual

  5. Supernova Classification Using Swift UVOT Photometry

    Science.gov (United States)

    Smith, Madison; Brown, Peter J.

    2017-01-01

    With the great influx of supernova discoveries over the past few years, the observation time needed to acquire the spectroscopic data needed to classify supernova by type has become unobtainable. Instead, using the photometry of supernovae could greatly reduce the amount of time between discovery and classification. For this project we looked at the relationship between colors and supernova types through machine learning packages in Python. Using data from the Swift Ultraviolet/Optical Telescope (UVOT), each photometric point was assigned values corresponding to colors, absolute magnitudes, and the relative times from the peak brightness in several filters. These values were fed into three classifying methods, the nearest neighbors, decision tree, and random forest methods. We will discuss the success of these classification systems, the optimal filters for photometric classification, and ways to improve the classification.

  6. Diagnosis, treatment and follow-up of patients with tetrahydrobiopterin deficiency in Shandong province, China.

    Science.gov (United States)

    Han, Bingjuan; Zou, Hui; Han, Bingchao; Zhu, Weiwei; Cao, Zhiyang; Liu, Yingxia

    2015-06-01

    To summarize the clinical and biochemical data, mutation analysis, treatment, outcome and the follow-up data of patients with BH4 deficiency from 2004 to 2012 in Shandong province, China. We analyzed the clinical, biochemical and treatment data of 40 patients with BH4 deficiency. Urinary neopterin and biopterin were analyzed. Further BH4 loading tests were performed in suspected patients with abnormal urinary pterin profiles. The patients with BH4 deficiency were treated with BH4 and neurotransmitter after diagnosis. Blood phenylalanine level, clinical symptoms and mental development were followed up. 40 cases with BH4 deficiency were identified and all classified as PTPS deficiency between 2004 and 2012 in Shandong province, China. They were diagnosed at the age of 20d - 41m and most patients received treatment with BH4, l-dopa and 5-HTP after diagnosis. Seven different mutations (P87S, K91R, T106M, D96N, N52S, S21R, and L127F) were detected in 11 patients. But outcome assessments were not always available. We obtained 19 records of DQ/IQ assessment. In 9 patients (7 early and 2 late diagnosed) no development delay is observed, while in 10 patients (8 early and 2 late diagnosed) development was delayed. Our study emphasized that screening for BH4 deficiency should be carried out in all patients with HPA in order to minimize misdiagnosis. Although the outcomes of BH4 deficiency are highly variable, early diagnosis and treatment is essential for good outcomes. Copyright © 2014 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  7. Longitudinal Follow-up of Impedance Drift in Deep Brain Stimulation Cases.

    Science.gov (United States)

    Wong, Joshua; Gunduz, Aysegul; Shute, Jonathan; Eisinger, Robert; Cernera, Stephanie; Ho, Kwo Wei David; Martinez-Ramirez, Daniel; Almeida, Leonardo; Wilson, Christina A; Okun, Michael S; Hess, Christopher W

    2018-01-01

    Impedance is an integral property of neuromodulation devices that determines the current delivered to brain tissue. Long-term variability in therapeutic impedance following deep brain stimulation (DBS) has not been extensively investigated across different brain targets. The aim was to evaluate DBS impedance drift and variability over an extended postoperative period across common DBS targets. Retrospective data from 1,764 electrode leads were included and drawn from 866 DBS patients enrolled in the University of Florida Institutional Review Board-approved INFORM database and analyzed up to 84 months post implantation. An exploratory analysis was conducted to identify trends in impedances using a Mann-Kendall test of trend. There were 866 patients and 1,764 leads available for analysis. The majority of subjects had Parkinson's disease (60.7%). The mean age at implantation was 58.7 years old and the mean follow-up time was 36.8 months. There were significant fluctuations in the mean impedance of all electrodes analyzed that largely stabilized by 6 months except for the subthalamic nucleus (STN) target, in which fluctuations persisted throughout the duration of follow-up with a continued downward trend (p < 0.001). The drift in impedance observed primarily within the first 6 months is in keeping with prior studies and is likely due to surgical micro-lesioning effects and brain parenchyma remodeling at the electrode-tissue interface, typically at values approximating 1,000 Ω . The differences in impedance trends over time in the various DBS targets may be due to underlying differences in structure and tissue composition.

  8. Long term follow-up of a tobacco prevention and cessation program in cystic fibrosis patients.

    Science.gov (United States)

    Ortega-García, Juan Antonio; Perales, Joseph E; Cárceles-Álvarez, Alberto; Sánchez-Sauco, Miguel Felipe; Villalona, Seiichi; Mondejar-López, Pedro; Pastor-Vivero, María Dolores; Mira Escolano, Pilar; James-Vega, Diana Carolina; Sánchez-Solís, Manuel

    2016-03-02

    This study evaluates the impact over time of a telephone-based intervention in tobacco cessation and prevention targeting patients with cystic fibrosis (CF) in the Mediterranean region of Murcia, Spain. We conducted an experimental prospective study with a cohort of CF patients using an integrative smoking cessation programme, between 2008 and 2013. The target population included family members and patients from the Regional CF unit. The study included an initial tobacco exposure questionnaire, measurement of lung function, urinary cotinine levels, anthropomorphic measures and the administered intervention at specific time intervals. Of the 88 patients tracked through follow-up, active smoking rates were reduced from 10.23% to 4.55% (p = 0.06). Environmental tobacco exposure was reduced in non-smoker patients from 62.03% to 36.90% (p < 0.01) during the five year follow-up. Significant reductions in the gradient of household tobacco smoke exposure were also observed with a decrease of 12.60%, from 31.65% (n = 25/79) to 19.05% (n = 16/84) in 2013 (p = <0.01). Cotinine was significantly correlated with both active and passive exposure (p<0.01) with a significant reduction of cotinine levels from 63.13 (28.58-97.69) to 20.56 (0.86-40.27) ng/ml (p<0.01). The intervention to significantly increase the likelihood of family quitting (smoke-free home) was 1.26 (1.05-1.54). Telephone based interventions for tobacco cessation and prevention is a useful tool when applied over time. Trained intervention professionals in this area are needed in the environmental health approach for the treatment of CF.

  9. [The Octabaix study. Baseline assessment and 5 years of follow-up].

    Science.gov (United States)

    Ferrer, Assumpta; Formiga, Francesc; Padrós, Gloria; Badia, Teresa; Almeda, Jesús; Octabaix, Grupo Estudio

    This is a review of a prospective, community-based study with a follow-up period of 5years. It is a study of 328 participants aged 85 at baseline, of which 62% were female, 53% widows, and a third of them living alone. High blood pressure was observed in 75.9%, dyslipidaemia in 51.2%, and diabetes in 17.7%. At baseline the median Barthel Index was 95, the Spanish version of the Mini-Mental State Examination was 28, the Charlson index 1, the Mini Nutritional Assessment 25, the Gijón test 10, the visual analogue scale of the Quality of Life Test was 60, and with a mean of 6.1 prescription drugs. A lower quality of life was also associated with female gender, a phenotype of frailty, heart failure, and a high level of social risk. At 5years of follow-up, the mortality rate was high, with 138 (42.1%) of the population sample dying at the end of the period. It represents an annual mortality rate of 8.4%. Thus, a common denominator of this review has been the high importance of functionality and overall comorbidity factors associated with mortality in this very old age group, compared to other more traditional factors in younger populations. Several studies of frailty have also been assessed in this group, as well as falls, nutritional risk, diabetes and successful aging, including important aspects to better understand this population group. Copyright © 2016 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. One-year follow-up period after transumbilical thoracic sympathectomy for hyperhidrosis: outcomes and consequences.

    Science.gov (United States)

    Zhu, Li-Huan; Du, Quan; Chen, Long; Yang, Shengsheng; Tu, Yuanrong; Chen, Shengping; Chen, Weisheng

    2014-01-01

    Thoracic sympathectomy is considered the most effective method to treat palmar hyperhidrosis. We developed a novel approach for thoracic sympathectomy in patients with palmar hyperhidrosis through the umbilicus, using an ultrathin gastroscope. The aim of this study was to evaluate the continuing efficacy and patient satisfaction of this innovative surgery. All procedures were performed under general anesthesia and the patients were intubated with a dual-lumen endotracheal tube. After a 5-mm umbilical incision, the muscular parts of the diaphragmatic dome were incised with a needle-knife and the nasal gastroscope was advanced into the thoracic cavity. The sympathetic chain was identified at the desired thoracic level and ablated with hot biopsy forceps. All patients were followed up for at least 1 year after the procedure through clinic visits or telephone/e-mail interviews. From April 2010 to August 2011, a total of 35 patients underwent a transumbilical thoracic sympathectomy. Fifty-seven percent were male patients, with a mean age of 21.2 years (range, 16-33 years). The success rate after 12 months was 97.1% (34 of 35) for isolated palmar hyperhidrosis and 72.2% (13 of 18) for axillary hyperhidrosis. Compensatory sweating was reported in 28.6% of patients at the 1-year follow-up evaluation. There was no mortality, no diaphragmatic hernia, and no Horner syndrome was observed. Quality of life related to hyperhidrosis improved substantially in 27 (77.1%) patients, and improved in 4 (11.4%) patients at 12 months after surgery. A total of 94.3% of patients were satisfied with the excellent cosmetic results of the surgical incision. Transumbilical thoracic sympathectomy is an efficacious alternative to the conventional approach. This technique avoided the chronic pain and chest wall paresthesia associated with the chest incision. In addition, this novel procedure afforded maximum cosmetic benefits. Copyright © 2014 The American Association for Thoracic Surgery

  11. Positive Change in Feedback Perceptions and Behavior: A 10-Year Follow-up Study.

    Science.gov (United States)

    Balmer, Dorene F; Tenney-Soeiro, Rebecca; Mejia, Erika; Rezet, Beth

    2018-01-01

    Providing and learning from feedback are essential components of medical education, and typically described as resistant to change. But given a decade of change in the clinical context in which feedback occurs, the authors asked if, and how, perceptions of feedback and feedback behaviors might have changed in response to contextual affordances. In 2017, the authors conducted a follow-up, ethnographic study on 2 general pediatric floors at the same children's hospital where another ethnographic study on a general pediatric floor was conducted in 2007. Data sources included (1) 21 and 34 hours of observation in 2007 and 2017, respectively, (2) 35 and 25 interviews with general pediatric attending physicians and residents in 2007 and 2017, respectively, and (3) a review of 120 program documents spanning 2007 to 2017. Data were coded and organized around 3 recommendations for feedback that were derived from 2007 data and served as standards for assessing change in 2017. Data revealed progress in achieving each recommendation. Compared with 2007, participants in 2017 more clearly distinguished between feedback and evaluation; residents were more aware of in-the-moment feedback, and they had shifted their orientation from evaluation and grades to feedback and learning. Explanations for progress in achieving recommendations, which were derived from the data, pointed to institutional and national influences, namely, the pediatric milestones. On the basis of follow-up, ethnographic data, changes in the clinical context of pediatric education may afford positive change in perceptions of feedback and feedback behavior and point to influences within and beyond the institution. Copyright © 2018 by the American Academy of Pediatrics.

  12. Newborn follow-up after discharge from the maternity unit: Compliance with national guidelines.

    Science.gov (United States)

    Roisné, J; Delattre, M; Rousseau, S; Bourlet, A; Charkaluk, M-L

    2018-02-01

    In the context of shorter hospital stays in maternity units, in 2014 the French health authorities issued guidelines for newborn follow-up after discharge from maternity units. A medical visit is recommended between the 6th and 10th day of life, as are home visits from midwives. This study was designed to evaluate compliance with these guidelines. The study was observational, prospective, multicenter, and was conducted in March and April 2015 in three maternity units in northern France that participate in the Baby Friendly Hospital Initiative (BFHI). Follow-up practices (medical visit between the 6th and 10th day, home visits from a midwife) and demographic, social, and medical data were recorded during the stay in the maternity unit, and through a phone interview 1 month later, in singleton term-born infants. The study population included 108 mother-infant pairs. The recommended medical visit was effectively performed by a physician between the 6th and 10th day of life for 20 newborns (19%) (95% CI: [11; 26]). During the 1st month, at least one home visit from a midwife was recorded for 96 mother-infant pairs (89%). The only factor positively correlated with a medical visit between the 6th and 10th day was the mother's choice, made early during the hospital stay and independently of the real length of stay, for early discharge from the maternity unit. Compliance with national guidelines was poor for the recommended medical visit between the 6th and 10th day of life. Information needs to be improved. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  13. Site-level progression of periodontal disease during a follow-up period

    Science.gov (United States)

    Morozumi, Toshiya; Nakagawa, Taneaki; Sugaya, Tsutomu; Kawanami, Masamitsu; Suzuki, Fumihiko; Takahashi, Keiso; Abe, Yuzo; Sato, Soh; Makino-Oi, Asako; Saito, Atsushi; Takano, Satomi; Minabe, Masato; Nakayama, Yohei; Ogata, Yorimasa; Kobayashi, Hiroaki; Izumi, Yuichi; Sugano, Naoyuki; Ito, Koichi; Sekino, Satoshi; Numabe, Yukihiro; Fukaya, Chie; Yoshinari, Nobuo; Fukuda, Mitsuo; Noguchi, Toshihide; Kono, Tomoo; Umeda, Makoto; Fujise, Osamu; Nishimura, Fusanori; Yoshimura, Atsutoshi; Hara, Yoshitaka; Nakamura, Toshiaki; Noguchi, Kazuyuki; Kakuta, Erika; Hanada, Nobuhiro; Takashiba, Shogo; Amitani, Yasuharu; Yoshie, Hiromasa

    2017-01-01

    Periodontal disease is assessed and its progression is determined via observations on a site-by-site basis. Periodontal data are complex and structured in multiple levels; thus, applying a summary statistical approach (i.e., the mean) for site-level evaluations results in loss of information. Previous studies have shown the availability of mixed effects modeling. However, clinically beneficial information on the progression of periodontal disease during the follow-up period is not available. We conducted a multicenter prospective cohort study. Using mixed effects modeling, we analyzed 18,834 sites distributed on 3,139 teeth in 124 patients, and data were collected 5 times over a 24-month follow-up period. The change in the clinical attachment level (CAL) was used as the outcome variable. The CAL at baseline was an important determinant of the CAL changes, which varied widely according to the tooth surface. The salivary levels of periodontal pathogens, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, were affected by CAL progression. “Linear”- and “burst”-type patterns of CAL progression occurred simultaneously within the same patient. More than half of the teeth that presented burst-type progression sites also presented linear-type progression sites, and most of the progressions were of the linear type. Maxillary premolars and anterior teeth tended to show burst-type progression. The parameters identified in this study may guide practitioners in determining the type and extent of treatment needed at the site and patient levels. In addition, these results show that prior hypotheses concerning "burst" and "linear" theories are not valid. PMID:29206238

  14. Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: A study from Eastern India

    Directory of Open Access Journals (Sweden)

    Shakya Bhattacharjee

    2013-01-01

    Full Text Available Introduction: Our present observational study attempted to evaluate the clinical profiles, diagnosis, treatment and follow-up results of 51 pediatric neurocysticercosis patients over a mean duration of five years (from January 2006 to December 2010. Materials and Methods: Diagnosis was mainly based on clinical features, computed tomography (CT/magnetic resonance imaging scan and exclusion of other causes. Patients with active, transitional cysts and seizure were treated with albendazole for 28 days, steroids and anticonvulsants. Results: A total of 38 patients completed this study. Mean age of the presentation was 8.47 ± 3.19 years 52.6% of the patients were female. Overall patients presented with generalized seizure in 55.3%, focal in 31.6%, headache ± vomiting in 63.2%, focal neurodeficit in 10.5% and combination of symptoms in 60.5% cases. Contrast CT brain showed a solitary lesion in 27 (71.1% and multiple in the rest. At presentation lesions were transitional in 58.2%, inactive in 20% and mixed in 14.6%. After a mean of 2 years, seizure persisted in 9 (23.7% and headache in 8 (21.1% of whom six had normal electroencephalography (EEG while one each showed focal slowing, generalized slowing and epileptiform discharges. During the follow-up, CT scan brain 44.7% lesions calcified, 31.6% disappeared, 10.5% regressed and the rest persisted. Conclusion: Solitary ring enhancing lesions (transitional stage involving the parietal lobe was the commonest CT picture at presentation. Generalized tonic-clonic seizure was the most common type of seizure. Number of lesions, persistence of lesion, number of seizures, EEG abnormality at presentation were not found to be prognostically significant (P > 0.05.

  15. Relationships in couples treated with sperm donation - a national prospective follow-up study.

    Science.gov (United States)

    Sydsjö, Gunilla; Svanberg, Agneta Skoog; Bladh, Marie; Lampic, Claudia

    2014-08-07

    Long-term follow-up on relationship quality in couples who use sperm donation is scarce. Therefore, this study aimed to analyse changes over time in satisfaction with relationship in heterosexual couples who were scheduled for treatment with sperm donation and IVF couples treated with their own gametes and to compare the two groups undergoing different treatment for infertility. A prospective follow-up study in which data were collected twice on two groups; couples receiving sperm donation and IVF couples using their own gametes. The ENRICH instrument was used to gain information about the individuals' subjective experience of their relationship at the time of acceptance for treatment and again 2-5 years later. At the time of acceptance for treatment the men and women in the two groups assessed their relationships as being very solid on all dimensions and that there were no differences between the two groups. At the second assessment there was a decline in the satisfaction scores on the dimensions "Children and parenting" and "Egalitarian", while an increase in scores was observed on "Conception of life" and "Conflict resolution" both for men and woman and also for the two groups. For the couples that had a successful treatment and gave birth to a child/children there was a decrease in satisfaction of the relation in the sperm donation group as well as in the group of couples having IVF with own gametes. In conclusion, the overall quality of relationship is stable in couples receiving donated sperm and does not differ from couples undergoing IVF-treatment with own gametes.

  16. Follow-up of pregnant woman 16 years after exposure in Xinzhou radiation accident

    International Nuclear Information System (INIS)

    Zhang Zhaohui; Zhang Shulan; Jia Tingzhen; Liu Qingjie; Liang Li; Su Xu; Ma Liwen; Qin Bin; Chen Sen; Wang Wenxue

    2010-01-01

    Objective: To investigate the late effect of radiation on child-bearing women, through observing 'Fang', a 19-week-pregnant woman at age of 23, who was exposed to 60 Co radiation in Shanxi Xinzhou radiation accident in November, 1992 and diagnosed as moderate bone marrow type acute radiation sickness and recovered after 16 year of follow-up treatment. Methods: Clinical data including medical history, physical examination, laboratory data, imaging findings and consulting relevant departments were reviewed. Results: The followed-up woman 'Fang' often felt weak and caught cold after recovery. When she was 32 years old (9 years after radiation), her hair turned grey, but without hair loss. Her menstrual quantitiy was lessened since 31 years old (8 years after radiation). She was remarried and pregnant twice in the same year. At the first time she underwent artificial abortion and the second child suffered from intrauterine death after 6 months of pregnancy. The physical examination found bilateral degree I thyroid enlargement and sparse armpit hair. The laboratory test showed the increased levels of triiodothyronine, thyroxine and anti-thyroid peroxidase antibody (TMAb) and the decreased thyroid stimulating hormone (TSH). Unstable chromosome aberrations were totally lost and stable aberrations in chromosomes were detected by fluorescence in situ hybridization (FISH). The dose estimated with the residue chromosome aberration was 0.76 Gy. Other laboratory results were normal. Ultrasonic test showed diffuse lesion in bilateral thyroid and multiple cystic nodules in right lobe of thyroid, which was considered to be nodular goiter. The examination of bone mineral density (BMD) showed osteoporosis from the second to the fourth lumber vertebra. There were no diseases associated with radiation based on the consultation from related departments. Conclusions: Intrauterine death after 6 months of pregnancy might be associated with the previous exposure. There is no evidence of

  17. [CLINICAL EFFICACY OF SUBLINGUAL IMMUNOTHERAPY FOR JAPANESE CEDAR POLLINOSIS IN THE FIRST FOLLOW-UP YEAR].

    Science.gov (United States)

    Yuta, Atsushi; Ogawa, Yukiko; Suzuki, Yusuke; Arikata, Masahiko; Kozaki, Hideaki; Shimizu, Takeshi; Ohta, Nobuo

    2015-12-01

    The first drug of sublingual immunotherapy (SLIT) for Japanese Cedar pollinosis (JCP) was purchased in 2014.   The purpose of this study is to clear the clinical efficacy of SLIT by comparing with other therapies, such as subcutaneous immunotherapy (SCIT), or other pharmacotherapy.   We started SLIT at our clinic in October-December, 2014. We compared the clinical efficacy of 191 SLIT with 48 SCIT, 191 primary pharmacotherapy that started therapies before pollen dispersal, 141 pharmacotherapy that started therapies after pollen disposal, or 169 non-treatment in the first follow-up year. The clinical efficacy was evaluated with quality of life (QOL) scores by Japanese rhino-conjunctivitis QOL questionnaire (JRQLQ No1), symptoms of nose and eye by visual analog scale (VAS), symptom scores and combined symptom-medication scores (SMS).   Mild adverse events (AEs) were observed in many cases, but no patient was discontinued by AEs in SLIT patients. Five cases by unknown reasons and 3 cases by inevitable reasons were dropped out before pollen. Adherence of SLIT was 89±12%. SCIT was better than SLIT in most assessments, but not significant. Both SCIT and SLIT were significantly better than other pharmacotherapy. Patients, whose symptom scores of nose and eye were 0 or 1 point without any rescue drugs, accounted for 16.8% of total SLIT in the first follow-up year.   SCIT was slightly better than SLIT in reducing symptoms and SMS of JCP, and in improving QOL. However, the differences were not significant. SLIT was significantly effective than other pharmacotherapies.

  18. Patient's needs and preferences in routine follow-up after treatment for breast cancer

    NARCIS (Netherlands)

    de Bock, GH; Bonnema, J; Zwaan, RE; de Velde, CJH; Kievit, J; Stiggelbout, AM

    2004-01-01

    The purpose of the study was to analyse the needs of women who participated in a routine follow-up programme after treatment for primary breast cancer. A cross-sectional survey was conducted using a postal questionnaire among women without any sign of relapse during the routine follow-up period. The

  19. Patient preference regarding assessment of clinical follow-up after percutaneous coronary intervention: the PAPAYA study

    NARCIS (Netherlands)

    Kok, Marlies M.; von Birgelen, Clemens; Lam, Ming Kai; Löwik, Marije M.; van Houwelingen, K. Gert; Stoel, Martin G.; Louwerenburg, J. (Hans) W.; de Man, Frits H.A.F.; Hartmann, Marc; Doggen, Catharina Jacoba Maria; van Til, Janine Astrid; IJzerman, Maarten Joost

    2016-01-01

    Aims: To keep patients in long-term clinical follow-up programmes after percutaneous coronary intervention (PCI), knowledge of the patient-preferred mode for follow-up assessment is crucial. We systematically assessed patient preference, and explored potential relationships with age and

  20. Psychologic impact of follow-up after low-risk gestational trophoblastic disease

    NARCIS (Netherlands)

    Lok, Christine A. R.; Donker, Mariëlle; Calff, Mart M.; Massuger, Leon F. A. G.; Ansink, Anca C.

    2011-01-01

    To investigate the psychological consequences of hCG measurements during follow-up in patients with low-risk gestational trophoblastic disease. The length of follow-up of patients with molar pregnancy and spontaneous normalization of the hCG level is currently discussed, in consideration of the low

  1. Radiation exposure during follow-up of adults with congenital heart disease

    NARCIS (Netherlands)

    Hoffmann, Andreas; Engelfriet, Peter; Mulder, Barbara

    2007-01-01

    Adult patients with congenital heart disease under follow-up often need to undergo diagnostic procedures which expose them to radiation. To evaluate radiation doses in adult patients with congenital heart disease during follow-up. Data on diagnostic procedures were used from the European Heart

  2. Variation in Follow-Up Visit Practices Across Clinicians and Conditions

    Directory of Open Access Journals (Sweden)

    Caterina Yuan Liu

    2015-12-01

    Full Text Available Background: Specialty care access is increasingly constrained due to increasing demand for specialty care. Although much attention has been placed on the initial referral decision, much less is known about follow-up visit patterns. We examined the patterns of follow-up visits for new patients to a university-based cardiology practice and identified independent predictors of follow-up visits. Methods: This is a retrospective cohort study of new patient visits using electronic medical record data. The primary outcome was a follow-up visit. Results: Substantial variation in practice patterns by provider persisted after accounting for patient and disease factors. Most follow-up care was concentrated in a small population of patients. Conclusion: Specialty care follow-up visits may represent a significant opportunity for standardization and quality improvement, and further studies are warranted to understand follow-up visits in specialty care. Implications: Better understanding of between-provider differences could identify ways to reduce unnecessary follow-up visits. Level of Evidence: Single-institution study.

  3. A Research on Students' Needs for Follow-Up Curriculum of College English

    Science.gov (United States)

    Jin, Jie; Liu, Hengying; Zhang, Yan

    2015-01-01

    Increased universities and colleges offer the undergraduates with more follow-up courses with the further reform in college English education in China. An investigation on self-evaluation, difficulty, and willingness of undergraduates in learning English further was made in order to design more appropriate and adaptable follow-up courses. This…

  4. Utility of Follow-Up Skeletal Surveys in Suspected Child Physical Abuse Evaluations

    Science.gov (United States)

    Zimmerman, Stephanie; Makoroff, Kathi; Care, Marguerite; Thomas, Amy; Shapiro, Robert

    2005-01-01

    Objective: To evaluate the utility of a follow-up skeletal survey in suspected child physical abuse evaluations. Methods: In this prospective study, follow-up skeletal surveys were recommended for 74 children who, after an initial skeletal survey and evaluation by the Child Abuse Team, were suspected victims of physical abuse. The number and…

  5. Breast cancer follow-up: from the perspective of health professionals and patients

    NARCIS (Netherlands)

    Kwast, A.B.G.; Drossaert, Constance H.C.; Siesling, Sabine

    2013-01-01

    Increased breast cancer incidence and better survival have raised the number of patients requiring follow-up care. Despite guidelines, there is controversy about appropriate breast cancer follow-up. Therefore, semi-structured interviews were conducted in two hospitals with 23 patients and 18 health

  6. Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up

    NARCIS (Netherlands)

    Korfage, I. J.; Essink-Bot, M.-L.; Janssens, A. C. J. W.; Schröder, F. H.; de Koning, H. J.

    2006-01-01

    To document anxiety and depression from pretreatment till 5-year follow-up in 299 men with localized prostate cancer. To assess, if baseline scores were predictive for anxiety and depression at 1-year follow-up. Respondents completed four assessments (pretreatment, at 6 and 12 months, and at 5-year

  7. Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols

    DEFF Research Database (Denmark)

    Seppälä, Toni; Pylvänäinen, Kirsi; Evans, Dafydd Gareth

    2017-01-01

    We have previously reported a high incidence of colorectal cancer (CRC) in carriers of pathogenic MLH1 variants (path_MLH1) despite follow-up with colonoscopy including polypectomy.......We have previously reported a high incidence of colorectal cancer (CRC) in carriers of pathogenic MLH1 variants (path_MLH1) despite follow-up with colonoscopy including polypectomy....

  8. Effective follow-up consultations : the importance of patient-centered communication and shared decision making

    NARCIS (Netherlands)

    Brand, Paul L. P.; Stiggelbout, Anne M.

    2013-01-01

    Paediatricians spend a considerable proportion of their time performing follow-up visits for children with chronic conditions, but they rarely receive specific training on how best to perform such consultations. The traditional method of running a follow-up consultation is based on the doctor's

  9. Irritable bowel syndrome--prognosis and diagnostic safety. A 5-year follow-up study

    DEFF Research Database (Denmark)

    Svendsen, J H; Munck, Lars K; Andersen, J R

    1985-01-01

    with irritable bowel syndrome as the final and only abdominal diagnosis in the period 1977-79 were followed up in 1984. Seventeen patients died during the follow-up period; two of these were considered diagnostic failures (chronic pancreatitis and pancreatic cancer). Of the remaining 95 patients, 93 were...

  10. Strategies for follow-up care of non-compliant HIV-positive pregnant ...

    African Journals Online (AJOL)

    NM Jama, N Tshotsho. Abstract. In an effort to prevent mother-to-child transmission of HIV, this study was designed to explore and describe the strategies used by nurses as a follow-up with newly-diagnosed ... The strategies for following up non-compliant women are recommended as guidelines to promote compliance.

  11. Extended heart failure clinic follow-up in low-risk patients

    DEFF Research Database (Denmark)

    Schou, Morten; Gustafsson, Finn; Videbaek, Lars

    2013-01-01

    by NT-proBNP, might benefit from an extended HFC follow-up.Methods and resultsIn a multi-centre setting, we randomly assigned 921 clinically stable systolic heart failure (HF) outpatients on optimal medical therapy to undergo either an extended follow-up in the HFC (n = 461) or referral back...

  12. Infantile Amnesia across the Years: A 2-Year Follow-Up of Children's Earliest Memories

    Science.gov (United States)

    Peterson, Carole; Warren, Kelly L.; Short, Megan M.

    2011-01-01

    Although infantile amnesia has been investigated for many years in adults, only recently has it been investigated in children. This study was a 2-year follow-up and extension of an earlier study. Children (4-13 years old) were asked initially and 2 years later for their earliest 3 memories. At follow-up, their age at the time of these memories…

  13. Laparoscopy or clinical follow-up to detect occult diaphragm injuries ...

    African Journals Online (AJOL)

    The mean follow-up time was 24 months (median: 24; interquartile range: 1–40). There was no morbidity or mortality in Group B. Conclusions: Clinical and radiological follow-up are feasible and appear to be safe, in the short term, in patients who harbour occult diaphragm injuries after left TA stab wounds. Until studies ...

  14. Anxiety and depression after prostate cancer diagnosis and treatment: 5-Year follow-up

    NARCIS (Netherlands)

    I.J. Korfage (Ida); M.L.E. Essink-Bot (Marie-Louise); A.C.J.W. Janssens (Cécile); F.H. Schröder (Fritz); H.J. de Koning (Harry)

    2006-01-01

    textabstractTo document anxiety and depression from pretreatmenttill 5-year follow-up in 299 men with localized prostate cancer. To assess, if baseline scores were predictive for anxiety and depression at 1-year follow-up. Respondents completed four assessments (pretreatment, at 6 and 12 months, and

  15. Hearing screening follow-up return rate in a very low birth weight ...

    African Journals Online (AJOL)

    These may involve parental education and counselling, as well as involvement of nursing staff and medical professionals in implementation of EHDI programmes. It may be possible to improve followup by aligning follow-up screening with the day of neonatal follow-up clinics in provincial hospitals where such services are ...

  16. Follow-up of treated coeliac patients: Sugar absorption test and intestinal biopsies compared

    NARCIS (Netherlands)

    Uil, J. J.; van Elburg, R. M.; van Overbeek, F. M.; Meyer, J. W.; Mulder, C. J.; Heymans, H. S.

    1996-01-01

    Objective: To determine whether the sugar absorption test (SAT) during follow-up of patients with coeliac disease on a gluten-free diet (GFD) correlates with improvement of the villous architecture of the small intestine. Methods: The SAT was performed in coeliacs at diagnosis and during follow-up

  17. Initial non-participation and loss to follow-up in a Danish youth cohort

    DEFF Research Database (Denmark)

    Winding, Trine N; Andersen, Niels Johan; Labriola, Merete

    2014-01-01

    Initial non-participation and loss to follow-up in the Danish youth cohort Vestliv could introduce selection bias of the measured risk estimates......Initial non-participation and loss to follow-up in the Danish youth cohort Vestliv could introduce selection bias of the measured risk estimates...